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<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGP7</accession>
    <name>A0ABR3YGP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF32">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="476"/>
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    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
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            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="55483" checksum="BC5C58A4989D04C0" modified="2025-10-08" version="1">MAESELIAGTVSVTDEEKTAQAAISSSPGSDSDVGHTQTWTEEEEKAVVRKVDRTVMPILMLVFFALQLDRSNAGNALTDKFLVNVGITQNQFNIGTQLLNAGIVLLEIPSNLVLYRVGPKAWIGTQIFLWGLVATFQAFQKGLGGYLSTRLLLGLCESGFIPGSLFTISQWYRAHELSRRYAFFFLGNGVATAAGGLIAYGVLHMRGIAGLAGWQWLFILEGIFTILTGVVFVTLFPGLPSNPISFAGVSYFNDRELFILRQRKALDDPTAGPLHRRVSWEDIKVTLSSGKVWLHVLLTTVGLAPSTALWSYAPTIVASFGYNTLASNAMTSVGQWVSVTLVIIGGFIADRWGRRGFFVFIAVFIEFVFTVAYKCLPDHAGRSTKFALLTLASATCSWWHAAHGSWLAINARTPAERSIRMALFIMAANCAGIVGGQLFRSDDLPYYHRGWTIAVAFMAFSVAVTLALLVLYALANKRIKKEVDHNGTIVDKDGQPAASVAVKLYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHI9</accession>
    <name>A0ABR3YHI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="116" mass="12915" checksum="33CA2AC22F34A3F1" modified="2025-10-08" version="1">MDRNQGYLSETKILKVFGILDHIIATQDLLMSVAPIRIMVTGGVVSVMHFHVRSTTEDVDFILDPNVDAAVEYRTEFLQAVRTAEIAAGIHSGRFNDHNVVIYEGHNVVAYASKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI44</accession>
    <name>A0ABR3YI44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">CMW 5346</strain>
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    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000149">
        <property type="protein sequence ID" value="KAL1887089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP001583186">
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        <property type="entry name" value="MFS_dom"/>
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    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF81">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        <location>
            <begin position="554"/>
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        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="60622" checksum="740AC2A7AB66B188" modified="2025-10-08" version="1">MARHDIPSRNGDASSSDSDTVTQHDETSPLLLPNKPDDQPTSTRIRGLFWIEAALFTNVFLAGFDGTVTASTYAVITSEFQSANLASWISTSYLVTTTALQPLYGRLSDIVGRRACLLAATTLFGLGCLGCALSPDLGMLIAMRALAGAGGGGLMTMATIINTDLIAPEQRGMYQATQNILHGVGSILGASLGGTIAGILGWRFSFLVQVPICMAALVVARVVVPANITPRRQVAIKVIDSSYTEESGDGTPVVKRPMSTWEQVDFLGAILLIAGLSLFLAALSAGSNNGGDGGLAWTNPSVLGCLGGSIILLAAFLSVEARTTAVPLLPLSMLHGVERVSLLVANVCLGISGYGFLFLMPLFFQAVLLDSASVAGLRLVASSLATPLGGLTTGLAMKFLAKGYEDNSLTLLTTLARTGAIILFIGGIFNLALGMNDPSWMYATYLTVGGFGQGMSYPASLFRFIGACDFGEHAVATYLVYLVRSVGSVCGVAAISTIVQTHLVAQLTDVFAGTPGGADLIDTLTHSVEALRDLPVETRTIVQGIYYEACRRGLYFLLGVSSATVFCTLLLSTKKVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIH7</accession>
    <name>A0ABR3YIH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000101">
        <property type="protein sequence ID" value="KAL1888076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF6">
        <property type="entry name" value="PROLINE UTILIZATION TRANS-ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="744"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="750"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="761"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="878" mass="95254" checksum="91EBA9C3C84F4374" modified="2025-10-08" version="1">MAPKSRRVPQELRQRTEKSCDRCKSRKQKCGMVPGQAKCAHCVKYGYECLVTKPRKQRLYGSVEAHAERLMLLEGLVKHFVPEADLANTDGMKELARSLGVSLLPTAGATSTVTAGSRDNGGSPDDHDGLHDDSIADHPTSTSSSLVKAKKDNEMLVRDLQGQGQYIGQASSFFFQVRLRDALETWIGRDGGGGNGSGGSAGSPSSAGTPGRMLLFGPNPADNRRNSFDNTNNLGYPDLDALMMYFPLSLADLLPSHPASERWAVTQLLVRTFFDRVNNDFPVLHEATFLEQLGAWSRRPQEADQAWICTLLCVLMLAWRLVAPASVVTSMPTDTTATSSTTPAPASMPTANAAPLPPTIELHDLQEARWWHQAQALLPKVLFTSSMASVQALMLTALHLHNNNSRDVCWTLTGAAVRIGFAIGLHRDDVIEPAEGASAVTTPVARELRKRVWWTLYAFEQLQVSSHDRPSAIDSTKHLLAGAPRETILDMGAHNPPEYVVWSNRLVALLGAACRSLPETAATAVDAEGADGKQNKNQALLVSPLSPPAGLLRDLARWHATLPRHLSADLIEAMPPSFQRPLLLLHVQYNYVSALVSRYALLSRFTAVSKRVPLSEPVRAMADVCIQAGVLSCTLLLKLDAVGGFNALTWMDAYYLYSSVLIVVLAFVCEANSQTQDTAKEQAKELATADELRQLLGRCKILAAKHLANPVVPGTMRRWLTVVGELDAMACHFAKRRAAGEASEAAAASTTDNMDTTGHAQMLPTPQTQSQTQPPLMTPSPDGGNASDNENDNDNDVEEVPRTVYFDNNNNDYSKSTASFFPTDGSTTTLLDAPTATTDDYGPFQAAADAAEAGMWHEMHWEGISDLLLGVDSRSWGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIU2</accession>
    <name>A0ABR3YIU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000097">
        <property type="protein sequence ID" value="KAL1888234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="1">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="127" mass="13097" checksum="A043DDE6F826E61F" modified="2025-10-08" version="1">MAEDRQPSNVHEGATTAAADVDLVEDDVAAKAKSAEDRKAAVALASLDSVGGGNDAGKHVDQEAMNKAMKNLKLGASGTAAKKVKVDAADVALLVDQLEMTKVKATDLLKQHEGDAVKALRAYVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIU4</accession>
    <name>A0ABR3YIU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000098">
        <property type="protein sequence ID" value="KAL1888181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="230"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="382" mass="41020" checksum="1D375698A8139BF4" modified="2025-10-08" version="1">MLSVVHRPPANLAFGLSSNEMDASHHMAAIMEVDLRACQPNTLVDRINAVPAFKTSAAFFSFLRANLVLPHSEMSSNANTPVLGPVAHASKGSSTATTTTTTAAKPATNGAAVTLDDIPPLTLGVLSERADKVDALQLVADSIAQQRQTASRSMVFHPLSLAGLAVGLGVAYKLNPRSDLGMTMTVMSGVIMTYLMSIRYFSAQYIPMAESLKWDWIVPKNDDGEVVPDAEEDTVIGARYGEEMIGALVLRLVPFAGGEQGSSTSAAVTSASTTSSRKKNSKTSQAASNAHLKGGHGVVRAWTTRLRYRRRGIGGDLLQEAIQVTRERCGKDANIVFAENHANSVMVVPEMFNSPFRRVEQWAVGFLEKALAKPEPEPVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJN4</accession>
    <name>A0ABR3YJN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ndufs8, ubiquinone oxidoreductase 23 kd subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NdufS8</name>
        <name evidence="9" type="ORF">Sste5346_009601</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004538">
        <property type="entry name" value="PRK05888.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004539">
        <property type="entry name" value="PRK05888.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849:SF20">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="243" mass="27321" checksum="5BE4958C8658FEDE" modified="2025-10-08" version="1">MLSTQVARRAMSARVIGSPIAAAVAAANTTSTATSSMTVRIAASTLLTANNTPRRRTYATPVKSLPKGFRITPRPEWDQEKEGTMDKIGKYFLLLEMARGMYVLMEQFFRPPYTIFYPFEKGPISPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEERADGSRRTSRYDIDMTKCIYCGFCQESCPVDAIVESPNAEYSTETREELLYNKEKLLSNGDKWEPELAAAIRADSPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJP9</accession>
    <name>A0ABR3YJP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_010054</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000112">
        <property type="protein sequence ID" value="KAL1887659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF77">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="19"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="56029" checksum="8206E51D5814FC6F" modified="2025-10-08" version="1">MTSNFSAAWAKTTPLLIFSCFCLLTGDVLFGYDTGSYGGILANPGFLARFAPYHEATKTHAFDSLHTSLLSSLPFIGKFIGCLAAGPAIERVGHRMVFFALSLSSVVGVIIEITSTKYVQFLIGRIIVYISVGLVEVNVTTYQAEIVPAAFRGLVVVSLQLFLAIGTTIATGVNKAFSTSKTNVGWQVVTGIQFVFPLLICLFTFFIPNSPRWLLSKDRDDEAVNSLRRLRSKADVDTGHCEAEIAAIRDSLQENVHKASWFDLIRGTNLRRTLLVVAYYFFQQTTGQAFVSTYQTTFYKTNGFAAQAFTFPIITSCLGFLAVVPAMYLVDSVGRRITLLQSYLFQAFWLFLLAGLGSKTVRSTTEDNTVVASFMLYAISYNMGSASIPYLLGAEIPNSALREKTQALGSAWNVIWAFVTNFVIPYMINSIHFKVGWVFGGVSLVALVFTFFFLPETKGRALEEIDAIFSVPFNPCKPNVVPLTEQQHRIARLEGDDTDTKSGAEVTCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK09</accession>
    <name>A0ABR3YK09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">mRNA cleavage and polyadenylation factor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CFT1</name>
        <name evidence="7" type="ORF">Sste5346_009523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000091">
        <property type="protein sequence ID" value="KAL1888479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="98"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="603"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="469"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1325"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="521"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1327"/>
            <end position="1339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1485" mass="159121" checksum="1948AB61A6FB633A" modified="2025-10-08" version="1">MQCYTELTPPTGVTHSLTLALTSAKSNNLVVAKSSLLQVFATKAVATDLDAQADASSTAQAPYAPAAAYDNRINNDDGDGLEASFLGGDSALLRSDKGILTKLVLVAEFTLAGTVTGLARIKIAGTKSGGDALLLSFKDARLSLVEWDPESNDLSTISIHYYEQDELQGAPWAVPLGDYANFLVADPGSRCAALRFGARNLAILPFRQPDEEEDIDMDDDWDEELDGPRPAKDAASAVVTGAGAPIEDTPFAPSFVLRLSNLDPNLLHPVHLSFLHEYREPTFGILSSSTRPSTVLGRRDCLSYMVFTLDLQQKASTTILSVGNLPQDLFHVFPVPSPIGGALLIGTNELIHIDQSGRANGVAVNPFTKQSTSFGLADQSDLDMRLEGCNIEVLSPESGELLLVLNDGKIAVVKLAVDGRVVSGVSIKPVTQEAGGELLLSGVACLSRVGRQALFAGSEDADSIVLSWSRKQSETTRRKQKASDEFRDDDDQEDGEEMEDEEDDDDLYGDGPSTIQLSSTSGGGGGGGSGKNSGDLSFRVHDRLISIAPIRDMTFGTPPLLGEAGKTDSEKKIRSDLRLVCAVGRGRAGALALLNREINPEPIGIFDFSEAQALWTVCASKPIPKTLQGEKGGATVGDDYESPAQYDKFMIVATEEDDGFERSHVYAVTDSGFEKLTGTEFEPEAGTTLHAGTMGKHKRIIQVLKSEVRCYDGDLGLSQILPMVDEDTGAEPKILSASMTDKYLLVIRDDASAFVAEMNKDFELEEIEKEDETLTSTKWATGCLYNDTTGAFSDASNATNNILMFLLSEAGQFHIYSLPSLKQIYVADGLGYVPPLLSADYTARRGTTKEELTELLVADLGDTISKSPYIILRHSNDDLTIYQPIRANTTATPDNQLAKSLRFLKVPNSTFAKASAAPPQDDDTPAPRGMPLRAFSNIGGYSTVFLPGASPSFVLKSAKSSPKVLNLQGSAVRSLSSFHTQSSERGFIYIDDQGSSRVCSLPATTNFAELGVCVRKVPLNVDANTVAYHPPSEVYAVGASTLVGFELPKDESHRAEWAKESITFKPQVEQGQLQLVSSVNWTVIDTAEMEQYEVIMCVKTLNLEVSESTNERKQLVTVGTAISRGEDLAIRGRIYVYDVVTVIPEPGRPETNRKLKLVAKEDIPRGAVTALSEIGTQGLMLVAQGQKCLVRGLKEDGTLLPVAFMDMNCYVTSAKELPGTGLCVMADAFKGVWFTGYTEEPYKMILFGKSNTRLGAINVDLLPDGKELFIVATDGEGNIHVLQFDPEHPKSLQGHLLLHRATFCTGAHFATSSLLLPSTSVNDDEATANGATNGNGHANENGDDDANGMNVDADDEHQAGHPPPQHLLLASPTGMLASLAPLSESEYRRLSSLAGQLATSLTHTAGLNPKGYRMAAGADADPAIDAPGVDAAVGRSVVDGALLARWVELGSGRKSEIAGRVGFASADDVRAALEGVLGWSRMSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLK5</accession>
    <name>A0ABR3YLK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1889004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="751"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="751"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="789"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="810"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="931" mass="101829" checksum="155991BC2ACE9401" modified="2025-10-08" version="1">MSPRHLNRSMSSSSAAAAAAAANPYTNNPGFSGATTPLPSPFSPDAGMHNNYYANAANSGSGSVNNGSNNGGPGNSSNANNNNANNGGSPGSVAGGSAAGGSGGTPSGKRKQDDDESNAKQQRSKRNRYISIACNECKRRKIKCNGETPCLRCGNLNLACLYSPNCCSSSFKDSEEFKSMSEKIHSLEEQLENIVQSVNSLRQETQRLAPLQDRILPIPSSTVSPSPSSSIPSLHKPELAPIRQSHIFRGGPTSMAFTVDVAKNTLHNMGYSGEPQEDGGNGPAIEETPRTSPVLPPASMQTSSSIQPMSSRNQSPNDPLWEFDKDEMVRLCRLHEDEVGIMYPVVKIETVIEHAQNLFSWMESARKNGYMPPLNYDEAMTDIRTLTLKIIMCCGLAVEEHGHSEKAIRLYDSIQPITDGKLMSEPSDLANLPFLALVAGYRFLSNDEVLAWRVMGQVARHCLEQGLHRREGISKIADEQERRNAVNTFWTAYVLDRRWSFGTGLPYVLHDDKIDPNLPFPDEYPYLVAMITYSRLGAKIWSLVDFFEPAIIRDLKREEFETLDAEILQWYDSVPDAVKINNLDRDLPLPSTPSYNLQRLQIWTRLRLNQIRIWLNTPVLHSASSINDNMEQAQKVVDLAKDTIRYLSRLNNSSNLYRRIQVFYHQFLTSAIAVLFLASTHQPVQFSANCREEFYMAMNLVKDMSAKSWVSQRLWRTIRSLKAYAPRLGLQHQEEDQHYSSASGGVSGFSASARRGGSIASSSGSGYPTSSIGNNSTSNTWRPHPPHTYPSNSSNTTSPITTPAGAATNGPQTTPSTGAPQPQQQQPPTTQPQQQPTTAGASTTSSPDQQTANGVQIQTEMTRIFEGYMGMSGIPLPPAGTVLEGSKGAMAGASRSNPNNGNVPIDPKLAAANAEGLPYGEAMYEHLKNMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA9</accession>
    <name>A0ABR3YMA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009207</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF163">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="526"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="70"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="565" mass="59676" checksum="9757732298062A25" modified="2025-10-08" version="1">MADPLIADETRPLLAGTVYKTPSATTVAVNSHSDTDVEAVKHGSHSDDLTAFADDPDNPRNWPSAFRWTIAFLLAFMAFTVTFTCISVVPFASHIVDELEGHPKDGSGGGVGSASVLLVTIWELGEAAGPLAIAPLSETISWGRAKVLTATSVLFALATAMAAIAPSTTLFIAARGLTGLAVATNVLNPAIVGDMFPPDQRGSAMSLVQLTPLMGGAIGPAIGGALADTWGWRSVLWLSTGLAVACNVLVWAAFRETYPPAILSARRQRLRKERQALQAAKLAGAASVPFSPSSSSLSSSSDVPVTSDDPSSSSAPPILTTSPTPSGLRRIRDAVLRPAILLADSFVLASMAIYGAILFSYFYVMSVSLPDILEYRYGFSSAATGSSFLVFSLGAFCSVIICNHYLDPIYRHLTNTRGRISPEDGVTRIGRPEFKLPLTLSCGLLLPMAVAAYGWSAELILPLPCVLLSVGAMGASMMLTFIPLAAYVVDAFGLYAASAMTGVIVTRCLCGTFLPLTVAPLVAAYGYGWGFMVLAGICFVITPVPFAVYFYGEQWRQLSKYTRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMK7</accession>
    <name>A0ABR3YMK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">COMPASS (Complex proteins associated with Set1p) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SDC1</name>
        <name evidence="2" type="ORF">Sste5346_008801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="107" mass="10980" checksum="C3F73ADF80C11523" modified="2025-10-08" version="1">MADHDIEGRPSSDGADIAPEGSVDASMTDGAASPAPFHTHAGVGRTGTPVRGGERLESSSRAASAHPEASFTIPSEAPLNGAPVRQYINSKLTGPLLEGMKMIAKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP17</accession>
    <name>A0ABR3YP17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-methanol-choline (Gmc) oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008796</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="11"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="6">
        <location>
            <begin position="430"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65375" checksum="39B5BA94AEBA651B" modified="2025-10-08" version="1">MAFVANGNAYHFIVVGGGTAGNAIAGRLAENPQVRVLVIEAGAPNPDQLAEITTPSNAFNLRGSKHDWAYKSTMIKRDDYERIEKPNTRGKVLGGSSCANYYTWIPGSKPTFDDWEEFGGSEWKWDGCVDYLRKCATYHDEEKLYPSDLKKIGTGGPIQIAHADLVPEMKGFREALTQAWVSKGERLTEDIYEGEMRGLTHCVDTIHDGSRQGSFLYLKNKPNVSILYGVQSKELIVDPATNTCSGVTVIHPETKTELSVYATREVIVSQGVFETPKLLMLSGIGPQAELAKMGIDVKVESPHVGQHLLDHPIVPFVLQVKDGYGLDDYILRPGPKKDSALAQYATDKTGPASSGFLELVGFPRIDERLEKHEEYRAAKAANGGLDPFGPAGQPHFELDFVSIFSSAFQWHYPVPESGNYMTVIVDLLRPLSEGEVKLNSTDPLVQPNINLNFFGNDLDILAMREGVRWTYDLLTTGTGFKDIVVGEYPWKMPLNDDAQMKRAVLDRSQTGFHPCGTARLSQNIQQGVVDPKLRVHGVKNLRIADASVIPVIPDCRIQNSVYMIGEKGADIIKAAHTDLYESKGIPYFSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP61</accession>
    <name>A0ABR3YP61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28463" checksum="E2E870B29F37E4AE" modified="2025-10-08" version="1">MDGRLQGKTILITGASSGIGKSTAYEFAQSVPSGVKLVLTARRIDTLKGIAADLEKQFPKTKVLPVQLDVSDPAATQKFVDGLPAEYQEIDVLINNAGLVRGVDKAPAIQEDDLNVMFATNVHGLIHMTQAVLPRMLKRNNGAGAGDIVNIGSIAGREPYVGGGIYCATKAAVRSFTESLRKELIATRVRVIGVDPGQVETEFSIVRFYGDKSKADAVYAGCEPLTPNDVAESIVFAVGRRENVVVADTLLFPNHQASATIMHRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG8</accession>
    <name>A0ABR3YPG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="56"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="374" mass="40045" checksum="9F80D8BC261E9EAC" modified="2025-10-08" version="1">MSSSIVSSNATTVVTSATTMIEHTANLVLPSGDLGPSLRMATWVLVVLSGAFLVTRLYCKWRRHRALHLDDGFLVASWFMLIAAIVCTTVEISYGFGKHAATLAAESHNGSASDFVDRLNSISLTGQLAITFGICAQAWSKTSWAITLLRIASGRRLRGFMWFALVSMNIFFAGPAFGYWLQCTPVAKAWQPLLPGTCWNPKILLVVGIVASCYSGLMDLSFAIVPWLLLRHLQVSPAEKIGIAVAMSMGVFAAISAFIKASAMPSLASPDFSFDGVTLTLWSTAEPAVTIMAASVPMMRVLVQSVRKPASWGSSEEDPMPGATTEQTSTDNSATQLQQAAAAAGLPVREPVRSDLEQGIPLQTRPQQATQAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR84</accession>
    <name>A0ABR3YR84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">carbamoyl-phosphate synthase (ammonia)</fullName>
            <ecNumber evidence="7">6.3.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CPA2</name>
        <name evidence="16" type="ORF">Sste5346_008238</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="237"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="770"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="15">
        <location>
            <begin position="1035"/>
            <end position="1184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1890411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1184" mass="129840" checksum="BE3A4F18F1E46419" modified="2025-10-08" version="1">MMSAVSLAGRAPSRLLRHGRCLPTAVPSTRVAAFSVSAQAQLQQAISAQRPTTTQPKTLKTLNSYLTTRRTLTQSTKRAATAVDSAVTESVHNPKAYMQSGVVKPREHVDVKKVLVIGSGGLAIGQAGEFDYSGGQALKALKEAGVASVLINPNIATIQTNHSLADEVYYLPVTPEYVSYVIEREKPDGIFLSFGGQTALNLGVEMERRGLFKKYGVRVLGTSVRTLELSEDRDLFARALDEINIPIAKSIAVSTVDEALDAANKIGYPIIVRAAYALGGLGSGFANNEEELRNMSARSLTLSPQILVEKSLKGWKELEYEVVRDANNNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEEYHMLRSAAIKIVRHLGVVGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYTAAKIGLGHSLPELPNAVTKTTTANFEPSLDYIVTKIPRWDLSKFQHVKRDIGSAMKSVGEVMAIGRTFEESFQKAIRQVDPRFVGFQGDKFEDLDFELQNPTDRRWLAVGQAMLHENYSVQKVHDLTKIDKWFLYKLQNIVDTTRELQAVGSLGGLKRELLTKAKKMGFSDRQIASALGSTEDEVRAVRLQFGIRPWVKKIDTLAAEFPANTNYLYTTYNASTHDITFEDKGTIVLGSGVYRIGSSVEFDWCSVSAARALRAMGKKTVMINTVSTDSDEADRLYFDESSYERVMDIYELENASDVVVSVGGQLPQNIALRLQETGGAKVLGTDPKNIDKAEDRQKFSNILDNIGVDQPAWNELTSVADAAKFAEDVGYPVLVRPSYVLSGAAMTVIHSQEDLKDKLEAASNVSPDHPVVISKFIEGAQEIDVDGVASQGELILHAVSEHIEQAGVHSGDASMILPPVSLDDTTMDRVKEIAQKVAAALEITGPFNMQIIKAADPEGGLPMLKVIECNLRASRSFPFVSKVLGTNFIDAATHALVGQDVPAPVDLMKVKRDYVATKVPQFSWTRLAGADPFLGVEMSSTGEMACFGKDLIEAYWASVQSAMNFRVPEIGEGLLFGGETSKDWLAKVINFVGPMGYKLYAAEQHVKEFLEAESKTPIDVQVIEFPTEDKRQLREVFKKYDIRGVFNLAKARGKTVQDVDYVMRRNAVDFGVPLFMEPKTAILFAQCLSEKLPRAEGTPSEVRRWSDFIGGKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRN7</accession>
    <name>A0ABR3YRN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007955</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="60138" checksum="8ECEACAE8BD3D0E6" modified="2025-10-08" version="1">MDFDFPVAEILERLKLAGAALGIVTVAYLFIVSVYRLWFHPLARFPGPIANRISWIPGVIWTLKGRMPMETRRLHDRYGPVVRLSPNELAFNSVQAWTDVYGHKIGRLDLEKDPIHVGAVDPVPGVSTISMADRENHARQRKALSYGFSKKALWEQESLIQHFIDLLMVRLHGFAEKPNEGFDIVKWYNFMTFDVIGDLSFGESFGCLERGDFHFWIHLIFDAVKAGAIEQASRRFAAPGSWLQRRIQKACQGGLSKQRADHLSFSREKVMRRLQDTKSDRRDFIYYILKQGEHYDLSQNEVIVNAALFIVAGSETTASSLAAVTNFLLKNPSTYEKCKNEVRSVFDSEDQITVAMMDKLPYMNACLEEGLRMFPPAPIGFLRTIQAQGDVIDGHHIPGGTAVSVSTWCASHSAANFRDPDSFIPERWIDPAYDSDNKLASRPFSLGPRGCIGKDLSYMEQRVTLARILFNFELSLADDAHEWNTDNNMQNMKAYSTWQKPPLHVKLVDRKVPTSKYWQQKAEEAKAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRZ7</accession>
    <name>A0ABR3YRZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="338"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="607" mass="67836" checksum="C32C488BE49DDBFF" modified="2025-10-08" version="1">MATATKMMSVARQFKGINIAQVDIKPITAESHFSPPTSPAGSRVIPKGTVVKEGHQPLPVDILVEEDVAIVVRDGVTICADIYRPAKTSEPVPAILAAGPFGKNGGPNKNNFNKWPWRFGCPRIATSGLEKFEGPDPGYWCLHGYAIVHTDCRGTWNSTGNVILPSKKEGEDNYDIIEFVGQQPWCNGKVSMSGNSYLSMTQWFAGAENPPHLACLAPWEGVSDLYNDMLRIGGSPDPGFTAGLITGDIASSTGSRGDDLETMCYKYPTWNKYWEEHRPEFDKIKVPLYIVASWTNALHTYGTFRAWQKVSSTDKWLRIHNTHEWPDLYQKQSVEDLRKFYDYYMKYAVNDWPQTPKIRLSVLDAGGRDIVNKPEAEFPLVRTQPLKLYLDATHNTTSATAPTESVSSYDAATGESIFRITFPTKTKLIGYSKLRLWAEAEGSNDMDIFVILEKIDTATGNLLESCVTDVGYLRDNPDAERKELADKHAADPSFGASYFNSGPTGRLRASHRELDPAQATDLNPVYTHRQEQLLQPGEVVQLDIGFWPYGWIIHPHQELRLRISGVNPKPHLRPNDKPAVLRNKGRHIFYTGGDRASFLLLPLIPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT53</accession>
    <name>A0ABR3YT53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007853</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="45"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="307" mass="33162" checksum="7C4AC2B9FE39B8F0" modified="2025-10-08" version="1">MLAVDDPLIPQFHKDDAHSGVTITEHSHHDTYEAINPRKLNLAGKSVFITGASRGIGRSIAVSYTQAGVAFLALAARGSMDDTVKAIEKAAAEVKKPAPTLLRLTVDASDPKSVEAAAAKAKEALAGKPLDILVNNAGVLEPNAVVHESDPSDWWRTFEINLKGVYLASRALIPLLLEGQGDRTIVNLTSIGGILVMDGMSAYNTSKLSVCRLTEFLAQEYRDSKLVTMAVHPGGVVSDMSLSLPENLHGAITDTAELVADSIVYLTREPQHWLTGRYVSVQWDLTELEAKKDEVVSKDLLKNKLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTB5</accession>
    <name>A0ABR3YTB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007574</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="474" mass="50547" checksum="405EBC7725A0E6E5" modified="2025-10-08" version="1">MSAEAAQLETGEKAEAGHIDNLRSRDSEAPAARGVQFDNIPPNYWRSFRFLGSAFSVVLLASALFTNFNLPASALTVINADLGYSPAYIWISDASVVVSCVGMLIVGRLGDILGRRNFLIGGQVFGVVGSAICAKATSINMLVAGATIYGVATTTQLTFPFVIHELVPNKHRGVAQAIITVLVLPFAGFGSIIARNLIEYSALGWRWVYMINVIFNTVTLVLLAVCYFPPALNHLHTAWTWKTELRKLDYGGILIFTFMAVLILLGLNWGGSTYVWTDPHVLAPLIIGCVLIFVFGLYGFFSGWLDIVASVANGLVTEPGDLGLANGFLGSMKQLIGTISTSIYIAILSNRYAINYPKAVTAAALGAGLPESSINATFAAITNGTAAAYAAVPGMNSTIETAIAGGIKSAWASTFSTVYYASLAFAGLGIVAAFFSTDIDVHLNDYVNRRITGTEAMNVPDELTIKNAHLTDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTD4</accession>
    <name>A0ABR3YTD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">VPS37 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="9">
        <location>
            <begin position="147"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="26069" checksum="9B6405E043550826" modified="2025-10-08" version="1">MYATTAPIPPPKPGSHDASRRSTPATTQSPRQPPLPATPTSLPEAAAYTQAPTPPSIADPGDTWLPKALQDKSKQDLADVLASPELLSALTHSASTIHPSLSASYGTLQSALDENSELAKHLQELEARLAHQRSAIQAQLLGAHALERSWRAKQAAMDAALTPFAPASLYQQLAAGVNEQEQVCQALEESFLEGEGDGGLASEREASEWVRRYRDARKLYYLRQERKERWDEGRVGGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTD8</accession>
    <name>A0ABR3YTD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="708" mass="78192" checksum="9484D977D0B0FE24" modified="2025-10-08" version="1">MTADGLVSRGAVSSAWRTTTALATGALLFLAHPATALFNNGTIIAPCNSTLYCYGEILKGIELAAPFSDSKTFVDMPTVRPLDEVVAAFNNLTKPLSNNTELNDFLSTYFAPAGGELESVPTDQLTTNATFLNQINDTVIHQFVQKVIGIWPDLTRQYTGKTGNTSCTGCQSSFVPVNRTFVVAGGRFREPYYWDSYWIVEGLLRTGGSFVNISLNTIENFLDLVDLYGFVPNGARVYYLNRSQPPLLSQMIRIYIEHTNDTSILKRAVPLLIKEHDFWTTNRSVSVTAANNKTYTLNRYSVLNNQPRPESYLEDYISANNESYYAANGSVYKETQPLNSSQQAALYAQLASGAESGWDYGTRWLARPNDSATDTYFPLRSLNINNLLPVDLNSILYWNEITIGSFLNTTGNKTAAKKWAAAATNRSEAMFNLMWNETLFSYFDYNMSSNAQNIYVPRDNTTTVSAEETAPPGYQVLFDVAQLYPFWTGAAPAQLKNDPLAVKLAFKRVEAYLDTTDGGIPATNLETGQQWDQPNVWPPLQHVLMQGLLNTPATFGVNDTDYQDLQDLALRLGQRYLDSAFCTWYATGGSTTLTPQLNGFDSSANGTMFEKYTYNSTNGAGGGGEYTVVEGFGWSNGVLLWTADIFGNKLVRPNCGNITAAQITPGKRKRAVSEVHEGSGLNRRARPPSAVQIDPYDAKWIKMFGNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU2</accession>
    <name>A0ABR3YTU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PSF1</name>
        <name evidence="11" type="ORF">Sste5346_007727</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="9">
        <location>
            <begin position="61"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="10">
        <location>
            <begin position="182"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="231" mass="25379" checksum="42146A606B7D41A7" modified="2025-10-08" version="1">MYGDLGNKLVQHAKRTQNLAHLPPYQTEIVRAVTREVRDLDKDVALLLEPFQGNFDPSVEQATACALLVDHLAMRRNKRCLLAYHRTRTDKLEELVWKGSDVVDLSVQQVRDASGAPSAGGQSGGPGAAGGGDGLSSEASNQSSSLSPQEEDYVRQYSDLLAAYKGQWTDIDLTGSLEPPRDLFIDVRVLKDAGEIQTEYGSITLSRNSQFYVRQGDVERLIAQGYLQKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUK5</accession>
    <name>A0ABR3YUK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007459</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="141"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="796" mass="87035" checksum="60BA74DE1DE8D46F" modified="2025-10-08" version="1">MSEINSDWLLYTGCEPKKNRAKLVCIFCHSKKIKCDLQPRIDRGRNKCSKCDASGRECRPRTSKRTKRPTGPATATTASGNANSTAAKPTSSASSTTAVQHSGTTSYASSPDATHAAAASSPTAPTVATIATSVEVDVPVSQVNNSNSNNNSRNHRHSFSHHPTQQQQPSHTSHMASSSSSGLTPLPPPPPHHHHPSHTGQQQPPIMNAAMHSAVAAMGLAPGGPQTTASPTEGAGRSHVGDVDTGFLQLYGPENEYDAERQEIEAQLGAKSNLSDPRQQELLQSFAETYFEYCYPWCPVLERDTLSEALHRSPLLANALATAASHIQPPLVPHEGPGTYYKRASSLFYQDEEPDILTQIKAVSLFYWWAPRPPSTVHRHSSWWWTSVVIRHAQQMNFHREPRVDHPLRHRLDLSARRRIWWTAFARERLTALCQSKPCIIDPADCSISEPTLADFPPEPELQKKGEIFIQWVKLCAIIGKVAKVLMRPPADCVTEGVMGGGGSTPSGASYQPMHLRRELARWAQSLPAHLRLPIEGSRTQGFDRDVHQLHLPYLTTIIILNMKRSPHALPEALPPAILAASCIARILRDILSRGNVRYLMAITCWYSGMAFAALLQGAQIPELAAEANEALDVIAQAVSQLQAMWASANIIRQGFDRLRGSAAVAPTASIRYREVQLPVPAGGLNSVPVDGVGITRPGDFPAITTTPGAAPGIADTQDLDFDWVDFFPFVTPATNKIAEVLLNGKGHGPATRLPSPEDLLFQDAIFSNYQDIVEPFHDIFMSELIRQSWTENPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWF8</accession>
    <name>A0ABR3YWF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007198</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF315">
        <property type="entry name" value="TRANSPORTER MCH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="16571" checksum="602CEFFB1A7F255A" modified="2025-10-08" version="1">MSYCICMYTIASYATGGLGLSQTQAAALQSLLAAGFLVGRPLTGLLLDVGGRINVAILLNVAAGISCWAIWLPARSFAPMAVFALVQGCTGGAVWVAAAPVTVEMVGTARSGSALAMFWLAVSPSAAFSSPSAIGLLTYARDHLHETGPEAYAISIGVCGGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWU7</accession>
    <name>A0ABR3YWU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADE1</name>
        <name evidence="11" type="ORF">Sste5346_006742</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010568">
        <property type="entry name" value="PRK13961.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="35869" checksum="1DBA86BD8A5FD1F0" modified="2025-10-08" version="1">MTAVTTVDLPGLTKIATGKVREMFVDEADKSSLLFVATDRISAYDVVLENGVPNKANVLTQLTAYWFSVLTKPGVLPNQSAPLATHLISLAPGPTAKISDAERAILRGRCMRVRRLRMFPVEAIVRGYLAGSAFAEYSSKGTVHGEPVGVADSGSSSSAVRFPEGMVRCQKLPAPVYTPSTKAELGAHDENISRAQAAELIGNPAHAARIEELALAVYTAAAEHALKRGVIIADTKFEFGLDEETGEVVLADEVLTPDSSRFWVADQYEAGREQDSLDKQYLRNWLVSEGLKGKEGVTMPPEIVEQTSKRYTDVYERLTGQTLESALANLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX69</accession>
    <name>A0ABR3YX69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I Iterative PKS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006739</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05274">
        <property type="entry name" value="KR_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="1"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="796"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="796"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="938"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="828"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2253" mass="244573" checksum="24B02C77CC74F374" modified="2025-10-08" version="1">MLLEVVYEALDSAGIPVGSLSNTATSVFCGSFVRDYEQPCMRDPDTTPPYSATGNGIAILANRISHAFDFAGTSQTIDTGCSASMIAVHQACKSLLSGESNVGVAAGVGLIFSPNTLVPMANLNILGSDGRCYTFDERANGYGRGEGTGVLILKRLKDAIAANDTIRAVIRATASNQDGHTQGITLPSQARQVQNMSDIYRNSGLDITRTAYMECHGTGTQVGDVKETQAAAELFCKHRTSENPLIIGSVKTNIGHLEGSAGVAGLIKGILVVERGFIPKHLNFNSPNPNIDFDRMKLKIATDLTPWPVSGLRRASVNSFGFGGTNAHVVLDDTPHFLSERKIAGGHHNTFLFPGDELESRTRTNAQSPRRHLFVFSGHDEAGLTRVIESQAKYVAKNTSTVGFETNYAYTLLSRRSRLSWRTFIVASTATELYQKLETNCTPKPLRTRCTPKELAFVFCGQGAQWYAMGRELLKYQTFYSSISTASWYMSSILGSSLCFWDELHRGKELSQISDPQISQPATTAIQVALVDLLFSAGIVPTSVVGHSSGEIAAAYAAGAITREDAWKIAYFRGQAVSQISNLKPEIQGGMLAVALSEEGARNGIAEANVSSVDVACINGPSSVTLSGDANGIFVLHDFFRSRGHRATKVNVSTAYHSRHMQVIEGIYRDSLKDLGPPLATSRPVAFFSSVFGRQVSLSELGPEYWVKNLVQPVQFYQAAAVLMETTIPDSLLEALGNLWAQGFSFELNWPLTNPNTEDKPCHLVDVPSYPFDHSKKYWHESHLSSANRFRSHGREDIIGAPLENSTPQDPRWRGFFRVQENPWLEDHVIQRSIIYPAGGMIAMAVEAAKQLADHSRKILGYEVTNFKIVKPMLIPTSTQGLEHMLSAHILDEDDEDFQKSNSTYKFSILSKPTDELEQRLGTNAQRQACRYVQKLCHTPLNPRQFYETLDVIGMTYGPQFRNLVEIQRGDASAHAVIQIPDTKAQMPFKFEFDYIIHPATLDTMLQTVIPLGEDRGAMLPCSAGRIFVSATPPKGAGSRFRGFTTARKTASRGAMADITMFDEELRAPAVVFEDLLFKSASNQITPGSGGFLPSHRNLCSEIVWKQDASSIASLGFDFPSSIQGIVDLASHKNPALSILYHVPHDPNSRHHDGMNFSNAGIEHLDAVAEALKITRLILNNLTAGYETPRFSRCIVSGANSEKVLQHIRMLKETGPGFDRIQHTGTVSDNDKHGLVFCSVDEQMSVDSLTPCFQRVDDSGWLIVLSKMGGMIDSAQYEALQLVMQAAGFQVDNASAKTGSSLSAQKMPRQSHLEVTPAMKRDKLTVLLPHPMSTFVAKLKSTLRPILEQQLALDVHEININSVTNFKEQSDGFVLSLVEVDIPLITTLGPQLFKLLHGLLTGSRGVFWLTQGGQVDCTDPERSAFLGLARTLRSEQCKRKIVTLDIGSDLHGPSGNNSSRVPETLINSIVHIVKSNFKTTAVNKGLLSSPEDAEFAYSNGRLLIPRLMPLETLNRIIEQGPLVKQTPLLAKGRAMKLDMASLQAADGPRFVEDVEAFHSGLLPNEIRIAVVGTNLLPEDIIHATSGIPTQLVGTDVFGHVVETGIGAVGFQKGNYVVARTRGTLKTHVIVDASKVRRVESPGDWQGSCPTAFATAMYALNTSRRIMKGDFVLVYGVSSAYGQAAIQVALALGGNVLAACLAEDEKTMAREQFKIPSSHILDARSTSDEFETRVLDITQRFGVDAVFDPTSCHIEQAFVCVAECGRVIRVAQKGCRTPSPPLADKNVSFETVDINLLEARRPNEAQRLALDIDKILKLISGLDAMRCTIEHNMCGLQKALSEASTNPFVGPHLVFTESDAGANLVNTVVQSTSEAALSPSGTYLLIGGFGGLGRSIAEHLVKCGAKHIAFFSRSGASSKVAKAFITKLHASGVHARAFATDICNGEQLAVSIKKVQAVMPPIRGAIQCAGVVDDVAFPSMDYDRWQNAFEPKAVGSSNLHQQLPKDMDFFVFLSSSSGIIGNRGQANYSAGNCYQDALARHRSSLGMHSVSIDLGLVLGAGMVAENEGLLDAMKASGFIGIRIQDALSILDRAMALPGSETSLNVPAQIVTTVGTGGLTIQNQPSDPFWTRTALFRYLNQVDAPPHGLNSAARQAAGQDLRSAIRIAPTPEEAAQAVCTALIATVARRKGMVSDDFDRHQSLGSYGIDSLDSIFVLGWIARETGVTVQTVEGVTIAELSQDIARRAVTAEEETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYD4</accession>
    <name>A0ABR3YYD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SER2</name>
        <name evidence="12" type="ORF">Sste5346_006810</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07500">
        <property type="entry name" value="HAD_PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF2">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01137">
        <property type="entry name" value="C1.6.1:_Phosphoserine_Phosphat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01136">
        <property type="entry name" value="C1.6:_Phosphoserine_Phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="542" mass="57755" checksum="3A8FC28CF97C4B09" modified="2025-10-08" version="1">MATPSKAPISSPGSFSLELPQRGRRINHGQANRPATHYGIDEIVESGSEDTSSPSAPSLRPTPPVGVSRNDAYAAKPGLPRRFSGVPDPKSPPVVVDSGVAHDLIHVNCTPMPGVAPSGERLIATIFYRGHGSDRIGHVATSPAQSNAAGNGATGPNVPRGAVEASDAIAVDELPANLAPTAQPASFPMELPATDSEPPRDGIYGAYVSPICIAAFLHLMSTFPLRRAVGDESQGISGGTGAQHTEANPSNTAYSNGYGSDLNASYRYLDNTKQPRVVELILGPAPSLPLADLRRHEQLYRFEREWGVEVALQGDTPWRRHPRLVVFDMDSTLITQEVIDMLAEAMPPAVATKVADITHRAMQGELQFDDAFRERVRLLAGLPSTLFTDLRARLDVTNGVPALLVALRRLGVRTAVLSGGFQPLTGWLAGELGINHAHANNVVIDQEGRLTGEVTGAIVGRERKCELLKQIAIDEGVDLKQAIAVGDGANDLLMLEAAGLGVAWHAKPVVQLEADVRLNQPSLLDLLYLLGFTSTEIRELSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ23</accession>
    <name>A0ABR3YZ23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="12"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="503" mass="54916" checksum="F4C0F8F648B31B53" modified="2025-10-08" version="1">MPMNPKLYQWLIGCFAAVGSFTFGYDLGVIAEILPALQGVKGFSPSSNEQGLITSLLSVGAFCGAFFASWLADAIGRRGTILAATILFCFGAALQAGSQNNGFLMGGRFVTGGGIGIYCMIVPLYQAEIAHPSVRGYLTALQQLFLGLGGLISSWVGYGCYVHLTGEVRFRLPLALQIAPAAVLGCFIYMFPESPRYLMQKDRQEDALQTLANLHAHGDITNPLVLGQIAEIREHMDAARSIGNPWKEMVGSASNRRRLTIGITIQAATQLTGGSAISYFLPEIYDLMGFSTSRSLLINSISSIIALVGEISCMLLVDRLGRRWPLIIGSIVMSITFIIGAILLVKYPADQLNNSAHWGFTVVTWVFSFTYASTAGTISWVYPSEIFSNSSRSKSVAVCTMTSFAFSTFVSQVTPIALENIGWRYYILYVVCNLSNAFVFWAFFPETSGIPIEEMDNLFSEASLFIPLSKWTPTNDSGRTELEIRAEKQEVYVTNQENTANVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZB9</accession>
    <name>A0ABR3YZB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoplasmic reticulum lectin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Protein OS-9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Protein OS-9 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YOS9</name>
        <name evidence="11" type="ORF">Sste5346_006448</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
            <orientation evidence="1 7">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the OS-9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0430">Lectin</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045516839" description="Endoplasmic reticulum lectin" evidence="9">
        <location>
            <begin position="18"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="10">
        <location>
            <begin position="176"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="543"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="562"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="599"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="637" mass="68209" checksum="E23E40CFC3D6AFC9" modified="2025-10-08" version="1">MRSKTLLLLAALQLAAARQPGFSIHEDILAYPQFEVVFSDSYILEGDAQRLLDGAADPSAYQSNAAAASATPSSQSDVAHPGDESTAVKEHGAGSTSGATGKNGDDSDAADDGSEQVSETFEIMNVPPSRYLCSVPVLAPPAPPNQTATELARAEEARELARMSDRGIEIISTLEGECMYYVSGWWSYSFCYGKEIVQFHATTTKTGKPVKDPHSQEYILGRMQGQQNDNTAAGEAAAAAAAATAGNKMKQAKKDLDVQKPLGGNANSAGSTTTQPTGEVSDPYNTELVVKGDQRYMVQRLGMGTVCDLTGRDRTIEIQYHCNPGGTSDRISWIKEVTTCSYLMEVRTPRLCEEGAFLPPKPARAHPISCRQIVSSEEEVAKWHHQKTIEAYAAMQGIKAKEKATAAEEAQEGIEDIPGQGQAKNQDGIVVGGVVIGARKALGRGEDGQPPLKLELPKHFGRDGAELVKGQPRVVKVLVRAASKANGGEVSILSTDELKELNIRHDVIQELVGKLTKIAGGKAWRLEAVENPGESALEIRAVLEPEDGEEPEWGTGSGTPAKKAEKVDKDEKTEDAKEEAVEKPEKKKKKGTKVTVTVEKVDKKGKETEAPKAQDGGDAVDDGGEEGSEETFKKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZH2</accession>
    <name>A0ABR3YZH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-dependent ATPase fun30</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FUN30</name>
        <name evidence="7" type="ORF">Sste5346_006271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="720"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="1102"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="216"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="655"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1272"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1272"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1299"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1321" mass="146678" checksum="7465C93F504A52EE" modified="2025-10-08" version="1">MDSSPLPNRSRPAGSFASSSVSRRNPFTIAKAASLARSNSSNLSNKSSTAPSITAKPTQKTQRVQKTQTRGRLRRDEYSDGDDDVEDDDADGDFNVDESEEEEEEEEDDIEDSDKDDEDELAGVGGFANSPYFTQPTQAITQPVTQPTQLLKKPPLTLGSAKPLDTVPINIPSSSPARSIIEVPASSPFQSPKPKTATPAASSIVARGRLANLMAPVGTTYRSPAAQAPPKPAARHAADDEDDDRALDNIISIDDSSDDDNDRRRRGDIRPSSFRSPDKVQRPAAIATTLETEQEQNEDDAEYISSPPAPEHEEEGDVAKPMGRRMLDDRKIQTLVGKMLKTLRSKGYMDVPAEVCRTTLIDHKFNVEEAVMDVFDDLLAKEQEKKSRPASAAPVRPSPIAKNKVPEMIRSFSYQGGNGIGSNSKTTTANTSRDSTPATPSSQVSLKRSALSPDPRPKRRRLVQGRKYRDPTSSQVGSPIADKEESNLVDLDRSVSDDDDNASTPAIEISDDEPMEINDDDDGDVIDVDAEEEDDDENSGEIEKRVLEYFNTCTVDDLVAMLGAKARGKAETILSHRPFRSRASVTRIQTEPTGGGRNKKKAANIGEDIFDAVEEYVIALRAIDVVVSQCEQKGLQIRSTLHRWNVDFRGSNKLKPAGDGSGANGLLTPASEPEGPNGLLSAASGKSSNYEPLPIPQEPELMRGHCTMKGYQLYGMNWLWELYNRNFGCILADDMGLGKTCQVISFLSHLVESYTGDVNDESSRPWPNLVIVPPSTLANWKTEFKKFAPKVRVTTYNGTTAERDSIFHRIQARRDKHHVVLASYSQVVAKQDVDAVRKISPNVAIFDEGHKMKNSNTNVYKSLRRIDANWRLILTGTPVQNNLMEMINLLNFIQPTLFERHLDKLGALFSQRFTLQDVSNGALLFTDRVMRARQILEPFILQRRKEQVLSSMPIKTSRILLCELDDTQRPIYEAYERQFREGRERRAAGLKSAAPASSTGESARQAAVLGLSNDQNNVWVQLRKSAIHAQLFRRYYDDKKVQKMAQTLMKYVPQSELRQPNLGHLVNELCDCSDFELHTWCRDYSCIREFDTPDGLFLKSGKVRELLSLVRQFQKNGDRALVFTRFARVLNILRECLEHEKIQYVSLEGATRVDERQDIIDEFNQNADIPVFLLTTGSGGTGINLTAANKVVIFDQSDNPQDDVQAENRAHRLGQTRDVEVIKMVTKGTIEELVYKACQTKLELAERVTAGSASRAEELEVAEWGDGDRMAKAVEEQVRQMLMAKKDGGNEGATTTPPKSEDGDGEAKAEQPASRSRNARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZJ7</accession>
    <name>A0ABR3YZJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_006286</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013716">
        <property type="entry name" value="Adenylate_cyclase_G-a-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052595">
        <property type="entry name" value="LRRC69/RLP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48057">
        <property type="entry name" value="LEUCINE-RICH REPEAT SERINE/THREONINE-PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08509">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00789">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="14">
        <location>
            <begin position="659"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="15">
        <location>
            <begin position="1458"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="13">
        <location>
            <begin position="1812"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="137"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="272"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="348"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="600"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1135"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1976"/>
            <end position="2016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2287"/>
            <end position="2322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="600"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1152"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1223"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1981"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="2001"/>
            <end position="2016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="2291"/>
            <end position="2322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1893783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2322" mass="252578" checksum="A20626E2A89393A9" modified="2025-10-08" version="1">MHPSSSGRDHREHREHHQHRADFGNYRRDLAVLDADTRSGSGSGSGDNTGQHHGGRSGSAPQIPQLNSLGSPGLSQIAPWMSAGGAGSSNNNAAGVSTPSATGGGGGMATSFYNDSSENVSIASQLSPAFRTNSLSLSRHHSAQTPASASNESPDAAYFNDDRRPSVASIATTASSQGSKASDRRGGGFRKLQGFFGEEFPGRDNSDASLSTQGKETRSHSYSHGRPHRDRNHSNATDRDASPSSSRPRTPLPAPEVVPFLYQEADDIARYGEAPVRDTLSGPDRDRYVNDASGQNPPKTSSSSRSGHSLPHLPHHHHRHNKSNDDPRTIRQTISREDSIASMRERAAPAMYTSTRSRAQSPTPSGNSGSGSASFGGPKNSYTDGQVSPPGAHPKKGLLGRLRRNKDKDDGNSTGGGNNGNNGSNNGGASHTAHSIAAQLKKMPHHAHNLSSRPSRQELSRAEPGGHFFGSDMSLSQRFHGDFEGTQQPRHGSTSRQATFNNKFPFSKKSRTHRHVDEHDEMIGPTDRADNGTQFFLDTDLNNMDGILSRPLPLTPMDADAHRGADSDRGTNTPRINHYFQKHIPHLGTNHNSPAASTTAIAGPGIGPNANGGPNGPNGAWNAPDSWAVRRTGDDAASHHLPDSDDFGSPPRNPEEKVQNYCIRVFKSDGTFATLQMALTASVQDVVAQLAKRVFTESQNYQIVLKRHDIVRILSPAERPLMIQKRLLQQVGYEQRDHLEDLGREDNSYLCRFLFLAAHESDFQSRSHDLGFSRMPKLNHVDLSSRNLITIPITLYSKAADITSLNLSRNLSLDVPRDFIQSCLNLRDIKYSNNEARKIPHSLGRASRLTFLDVSNNRIETMEHAELEDITGVLKLNLANNRLKQLPTYFCAYHALRTLNISSNFLDKFPGFLCELESLIDLDLSFNLISSLPDAIGNLRNLEKFVITNNRLSGTFPPGFQDLQSLRELDIKYNTITSIDVISELSKLEILTADHNAISQFVGGFERLRSLKLNANPITRFEIINPLPTLKLLNLSNAQLASIDDSFNNMRNLERLHLDKNYFVSLPNQIGNLGRLETFSIANNSVGELPPEIGCLTELRVLDVRGNNIRKLPMEIWWANKLETLNASSNVLDNFPKPASRAPQVPGESNKDSMSSAAQGRMNSTVGTLSSTPSSEELNSDGSRRPSQASSTLLSVGPSPVPSGPDRKSSVVSVYGKGGRKTSIVSRSTAQGSGMATPTASSRKDSGLSSRITNTFAGSLRNLYLADNQLDDEVFEQLALLGEIRVLNVSYNDLTDMPQRSMTSWPQLVELYLSGNELTTLPADDLGEYSMLQVLHINGNKFTNLPADISRAKKLAVLDCGNNSLKYNISNVPYDWNWNLNRNLRYLNLSGNRRLEIKQTAYNAGAALRSAEQYADFNRLLKLRVLGLMDVTLTQPSVPDQSEDRRVRTSGSMAGFLPYGMADTLGKNEHLSTIDLVVPRFTSNANEGNEQDTLLCLFDGQALSSGGSKIAKFLHENFSRVFAAELKTLKVDQSETIEDGLRRAFLTLNKDLVTSSIQAEDRMPLSSSAPQPTAHRGSIAPMVLTKEDLNSGGVATVVYLQGQELYVANVGDAQAMLIQSDGSHKVLTRKHDPAEPSERSRIRDAGGWVSRNGRLNDVLDVSRAFGYSDLMPSVMAAPHVVHHTVREQDETVLLATKELWEYLSPGLVVDIARQERGDLMRASQKLRDLAMAYGASGKIMVMMLSLSDLKRKTERSRLHRGQSMSLYPSGVPEEAAQQFLPTRRGKRTKGDVLDSTLQRLDAEVPAPTGLIAIVFTDIKSSTTLWETYPAAMRSAIKLHNDVMRRQLRYIGGFEVKTEGDAFMVSFPTATSALLWAFAVQLQLLDAPWPTEMLNSVSCQPVLDKDNNVIFRGLSVRMGIHWGEPLCEPDPITRRMDYYGPMVNKAARINSIADGGQITVSSDFISEIQRCLETYQESPIGAGPGGSGEDGVGRGNAGGNGSISAAGSSVGGSSTAGTGFDDDTFAQTIRKELKALSSQGFAVKELGEIKLKGLENPEVVYSLYPHALAGRMEAHSHHMSVTAAVAAAASGVEGAALVNGASGGYHSGSTAGSTAAAAAAAVAAAGSANGGDASTIPAGGRVLPGSKLPAPTSAIILGDPDTDDLRVIPEVIWALWRVSLRLEMLCSSLEAVGGHGLQPPETELLERMKQRGANVTERFLMNFLEHQISRIETCISTLTLRHMAMGGGPIHHLDDLRASMTDIFAAFTHQMSELQAYRAKFGPLNAVHRAEDEMEVEEIDDDEEEDEEEDEDEEDEGSDTEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZU9</accession>
    <name>A0ABR3YZU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="129" mass="14570" checksum="E4A55B301226F532" modified="2025-10-08" version="1">MSRDPPTPDPKAILHERLNRSILMGVDPPVFPFLVANFLGRRDSMWVAGKKCLLATAACVHMNNILYCLLGHTKVRADIVESTMFAVAMNGNEVQLYVTWADTIGLDEEGNEIDEDNREEDDKEIYDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0T9</accession>
    <name>A0ABR3Z0T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sidoreflexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fsf1</name>
        <name evidence="10" type="ORF">Sste5346_006019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF6">
        <property type="entry name" value="SIDEROFLEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="167"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="200"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="34893" checksum="59E5CF30A6DECA08" modified="2025-10-08" version="1">MSASLPGSRELPASQYDLNTYWGRVKHTAGITDPRTLLVGSTGLEQAKKAIVAYKQGEVKEMTTELWTAKKIVDSTLHPDTGEPVMLPFRMSAFVLSNLVVTAGMLTPGLGTTGTILWQVANQSLNVAINNANANKSTPLSYGKLAQSYFLAVGASCSVAVGLNSLVPRLTKLSPSTRLVLGRLVPFAAVASAGALNVFLMRGEEMRTGIDVYPVGSGGEKAESLGRSKKAATIAVGETALSRVLNSSPIMVIPPLVLVRLQRTNWLKQRPQLTTPVNLGLILVTSYAVLPLALAAFPQRQKIAADSLEPEFHGRGGVNGMVEFNRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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    <name>A0ABR3Z0U7_9PEZI</name>
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        </recommendedName>
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    </gene>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Ophiostomataceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009465">
        <property type="entry name" value="Spondin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF15">
        <property type="entry name" value="TRANSPORTER SEO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51020">
        <property type="entry name" value="SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="269"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="332"/>
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            <end position="406"/>
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            <end position="501"/>
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    </feature>
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            <end position="41"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="515" mass="58606" checksum="D26177E3885CD66F" modified="2025-10-08" version="1">MAHSPVDAGTDADASISNPDLKGAHVVSSQEVSQHGSPESPTDHYNDAESSRANYIAGRGRVQRKWYAWFADTDTPAERKLIIKMDLLIMSFAFLAYWAKYIDQGNLTNAYISGMQEDLGFYGNQLVQLQTIFNVSYTVFMIPLTLLAAEYPRTIPACEFFWGLFTLLQYRAASFGELAAYRFMTGLFESGFYTSIHYVLGSWYRTDELGRRAGLFYVATCLGTMTTGFLASGIIKHLDGVHGLVSWRWLYIVCSVLTFPIGIFGLVFFPGTPDTTKSFWLTEEEKELARDRMRRIGGKPAIGFGAGWKVVRRFFFRWHIYVLGFILVPWIMTTQPSGNGAYTLWIKSLDKYSTSRINELTAINPGVGMALILLYSFLSDHLQTKIYIIVFQSLLQFSLQLAFPLWHHSSTAYKWSAVATGYGQNALSPILYAWANEICREDAEERAFVVSVMCAMSNVFATWVPLLVWQTVDAPEYHKGYTFTQVFIIVFMFCAIGLWWFDKRDQKRLYRKALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0V1</accession>
    <name>A0ABR3Z0V1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="23"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="12"/>
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        <location>
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        </location>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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        </location>
    </feature>
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        </location>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="700" mass="76228" checksum="77A28AA086D8CF76" modified="2025-10-08" version="1">MALKTTTANQLQHGHRRRVNKPVLVRGSQLSARYITERRIKHERKIRKQQQKQQEQRIQQEQSAASSATATPEPSTPPSESTSFQGMTAEKKEALQHILGRTLDEKDRSAADILATLYMTGMLDRKTPAASEASGASTPIHESDAEPSKVILPSMQQTEVMLEVWRAERSGVKSSAAPSTEAANAEPTTALSSSLMTPGLSASSSSSAMASAQSSFSLGSPVSQYARMPSPSGPPPPPYDAWRKSIGVAHGEAAPAPSASAPLPAPIPTTSKVTQSPFSTYAQNYFCSSRNSSSNNQAASGPNGMPSPPQSPTDAGRPREYSHKPAAPTNTLPTLPSIANLPTPPQSFSASMQPASYHQQAYHPHNAYQPRYNPQYELPAPMPTHRRSIHGGAEDIATTVVTLPPPGIGSSREPLTPVSPLTLPSAFGRRSTMPTMPSVATMINGPYHHNSPRMAAKMDARRDRMSSASSPSTSTTKKAMPKPHCNVKYETAELDFIMYQRTTKNRAWDDVTSSFNAALPRLRQYADMDCARLGGVGLAGSNSPGGADKMDRYRARPERTTPGLQASYYRQRLALPLLDEAGQLVFDDASNKQLFTEVMVRDDKSRKKLRRITTGPTAVAPTAAPSSSSKVNPDDARVHLVLYFPERVTYYDYWFVSEEDKALARQRTYERNMQRHQRGLPSWHPGNDDPDSGILTLGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z104</accession>
    <name>A0ABR3Z104_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Endonuclease</fullName>
            <ecNumber evidence="8">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NUC1</name>
        <name evidence="11" type="ORF">Sste5346_005999</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="10">
        <location>
            <begin position="105"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="9">
        <location>
            <begin position="106"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="38674" checksum="8CE3CF050FD2D9DE" modified="2025-10-08" version="1">MSKSTIAVIAAASAGVGAAATAAMFSLRSKPAERATPVPTATTTATTTSVSTAAVPATKVFSAPPPAPAPVPAPLPPVPATAAALVDPAGLFQYGFPGPVNDLAARSALVSSYDRRTRNPHWVAEHITPASLAVRDGDRQHSNFVEDTAVPEIFRAKLKDYFRSGFDRGHQVPAADCKWSQDAMNETFFLTNMCPQVGEGFNRDYWAHFEDFCRRLTTRYPSVRVVTGPLYLPKKDPVDNKWYVKYEMIGNPPNVAVPTHFYKVIYAETVPSTGPGGGNPGTGAPVALGAFVLPNAPIPNDKPLSDFEVPLEAVERASGLEFAAKLPPQRRRRLCAEASCSLVIKEYGDRQKQVAKQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Y3</accession>
    <name>A0ABR3Z1Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="63457" checksum="8E156AB4BC40D706" modified="2025-10-08" version="1">MATNGQHFDFVIVGGGTAGNVVAGRLAENPNVKILIVEAGYGQPEEVADIMTPAKAMDLRGTQYDWAYKTTMVKRDDYERIEKPNTRGKALGGSSSLNYFTWIPGSKGTFDLWEKFGGKEWTWDELVPYLRKSATYHDDEKLYPKDLHKIGGGGPLPIAHAELLPEMAGFRKAIEEAWISMGQPLTENIYDGEMIGLTHCVDSIYQGKRSNSVLFVRGKPNITILAQTNSKQLIVDPATKKVSGVTVIDASGKELTFYADREVILSQGVFESPKLLMLSGIGPAAELAKHNIPVIVDSPQVGQQLVDHPAVPFVLRVKDGFGMDDHLLHKGPLQEASVTAYNASRTGPLSSGNLEVVGFPRIDSYLEKDPVYVAAKKANGGLDPFCAQGQPHFELDFVSVFGSAFQWHYPTPKVGNYTSVVVDLVRPVSKPGSVTLNSANPLEQPNINLNFFESELDIIAMREGIRFSYDMLTRGAGFKDLVVAEFPWEMPLDDDKAMRHAVLDRCQTAFHPCGSNRLSQNIQQGVVDPALRVHGVTGLRVIDASIIPEIPDCRIQNSVYMIGEKGADLIKAAHKDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C3</accession>
    <name>A0ABR3Z2C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30059" checksum="596957B3C365491E" modified="2025-10-08" version="1">MVGSRLVHVAKDEIAKKHKVRILNPDRPGFGGTDGIEVEQVMETWRETIVALLKHLRISYVSVGCHSGGTIFALDLLLHHPEVMDPNKKAFLAIGAPWILPSHTSSTMMAAVQSLPSGILKHTDKVARLINNHIGPTVGFCFWLGSAVVAKVTPKTSRERLTKADSKESNPAEMEREGAKLEDDLWPKIIQRIYAEGVQGISSDALLFLQKPKGTNAQSNSGWGDWGDYDALVPRLAETLRASGRRLLVEVFYAEDDALIGGGGTKGPQVSCFLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3R4</accession>
    <name>A0ABR3Z3R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005695</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045988780" description="beta-glucosidase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="12">
        <location>
            <begin position="783"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="880" mass="93325" checksum="0236273DC64D4F8E" modified="2025-10-08" version="1">MVNSACVALVAAAAWARTAYGATVQRRDSVPAGYVAAPYYPSPLGGWTSDWTSAYDKAETLVSSMTLAEKTNITAGTGFFMGDPCVGNTGSALRVGFPQFCLQDSALGVRSTDHVTAFPAGITTGATWDKDLILARAQAIGEEFRGKGVNIYLGPTIGPLGRKPRGGRNWESFGADPVLQAVGGALTVQGVQSQGVIATVKHLIGYEQEMYRMYNVIMPGYSSNIDDRTLHELYLWPFAESVRAGAGSIMAAYNGVNGSACSQNSYLLNNLLKDELGFQGFVMSDWLGQMSGVASALAGLDMGMPGDEQIPLIGTSYFMYDLTRAALNGSVPMDRINDMATRVVAAWYQMGQDADYPPPNFSSNTEDATGLLYPGALFSPSGVVNQFVDVQGDHATVARQVATDAITLLQNNGSLLPLDLSRPLVVFGTDAAVNPSGANACADRACDTGTLGMGWGSGTANYPYFDDPITALKNRSTGGVTYHNYDSWPWFFPPSQSGDQVAVVFITSDSGENQDTVEGNHGDRDSAGLSAWHGGDALVQSVAKAYDNVIVVVHTVGPIVMDSWINLPSVKSVLVAHLPGQEAGESLADVLYGDVTPSGHLPYTIPKQESDYPSSLGLRGFALGQIQDTYSEGLYIDYRYLMKNNIAPRFAFGHGMSYTSFSLSSASIAVSTKLTTTLPAARPSKLPTPSYSNAIPPASEATMPAGFSTIWRYLYSWVSLSDAEADIAASTSSTYPYPAGYSTTQKQGPPAGGAQGGNPALFDVAYTLSVKVANTGKSASGKSVVQAYLQFPSSTSYDTPVVQLRDFAKTDTLAPGGSGTVSLQLTRKDLSVWDVVQQNWVLPGLPSADRYTIWLGEASDQLYTACYTDTLTCQGGLTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z8</accession>
    <name>A0ABR3Z3Z8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TIM9</name>
        <name evidence="14" type="ORF">Sste5346_005624</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="13">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="87" mass="10114" checksum="20DADE6BE28A243C" modified="2025-10-08" version="1">MDGLTASETRELEQRMQKRQVKEFIGVFSNLVDHCFASCIDDFTSKSVSTRESGCVTRCVQKYLATQQRLSERFQENTAEMNQQQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z497</accession>
    <name>A0ABR3Z497_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="150" mass="13903" checksum="4C415FE468E21512" modified="2025-10-08" version="1">MPGVPVDALDNLKAKFKSIFKKKGKAETAAPAAAAPAAPAEAAKPAEETKPADAAPAAKEAAPAAAPAAAEAPAAAEAAPAAEPAAAPAAAEPVVAAAEPAPVAEAAAPVAEAAPAAEAAPAAAAVEEAKPAEETKPAEAAPATGAISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z507</accession>
    <name>A0ABR3Z507_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22476" checksum="EF4C79C3A41E290E" modified="2025-10-08" version="1">MPAFPWEALHTDVAPPFADAQLNAALDFDLLGNASDMTSYPFFLSFDSENEASLNDFQASPWIFQNICTDGVSMQHASLVLPVSYTRQSRTRKELPPWLHKVPSTVHPHDPHIVRAFLEEFLVNMSYSFPTFQNFKVHGDTLPDLILAMAAVGGLFSKIDGSFRVAMSMYTDARRLASGRIWSQQCTSNTQYLDLVRALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z565</accession>
    <name>A0ABR3Z565_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Endocytosis and vacuole integrity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MON2</name>
        <name evidence="9" type="ORF">Sste5346_005202</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="8">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="6">
        <location>
            <begin position="200"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="7">
        <location>
            <begin position="1028"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="482"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="777"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1583"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="488"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="791"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1789" mass="193345" checksum="BDCD24F4246B917F" modified="2025-10-08" version="1">MTAQVLTAELGNLIQESKRKHNDLRQASEKSLEELKNLSDSSEANIGAELAQHANFVNPFIIACGTRTVKFTSIAIVCLQRLIAAKGVPRSRLDQVLQALREASSGGLDVQLRILQSLPSLLQLYAGDISGDLLITSLNICFVLQASKNVVVNNTASATLQQLLIAVFDKVAAEDKAHPSTPLVGEAPVQNGTVALHQAALDAYHAFNDICLLTEAGRPEHLRFSSLSITFGLELIESVLTNHPAIFSSHPEQTHVLRTRLMPFLTRSIVSKPNFPTAVRLVRVLYTLLKRHMALLADESGEALAALSHVLDHDSVLWKRVLCLEAFKGIFSDPALVRQLYILYDAKEGEKDILQELLATFVRVSTEKPSVIGLGYTSTIPVAGYSNNGAGSAEQAVMEANGMSGIVTSNSTTESASTGISSQWSAIRTPCIDQLDKAEPLSIPESYIFSLILACITSLSEGLAKFILPLTVPRENRNQKRMLKQDGRSNSPAPTDQPGTPTSAPGLERSASARKNPVPKNPLLLKDHPLHAEVKAYAEMIDRCWPAILATCSTFLYSALDSEYYHSLVRAFQRFTHVAGLLQLNTPRDAFLTTLGKAAVPPNVLTACHNAGARPMTPTSAGADTPNSLFGNARGLLSVDSLVSQSSAPEKPRQPSADLSAASINTRNLLCLRALLNLGIALGPTLESSWQIVLETLQQADFVLFTSGKAAGRTLAVVRSADPQAEAEATMLLQNFGSEIKAVETAASRLFESTIDFPNAAFVEFVVAICSLLEKRPESPTTADDNDSAIDDQTQSPQATPRKSSGAGVSFATEGGRLKTPVVKHKRVMSITTAPASTRTQEDQFVLAKLGDIASINLERLLYSAPEVSGWIPLTYELTATLGSAFTTPTVRMRAAETLVRFVLEATNAVAGEKEVTRSRMQLRLLEALRDSLLPLQSPDRSGSITTQATDIDIHKVILDGLKGLLEDSGEALISGWNVVFEIIDSLFTEGRPSSVEGNLSTSEGVLTTRSVRLIKPSFASLQLICSDFLSSLPNTCYLNLVNTLYKFCSQGDDLNVALTTVTFYWAISDFLHGRSSSMSIAAAMEGGSSDAALVKLANDTAHPGSGAALWMLLLLRLTAVTTDQRLELRNSAVQTLLRIIHAYGNNLTAEAWAVCIRSVIFRLLSSTEGRLRSASEKATTNKSTTTVAEWNETAVVIVNGVSELLANYLDVLASHAVFSSLWEDLLQHFAAMLNFKALNVSTAVFGSLAGILSKNDGRTRWSFDKKAVDLAWRLWSRGIPAPPDALSAEKERDRSSTRAEDNQKCLVSWVNAFLEIERLMRAEMDLEKTEQAMALLHDAVRGASPGGYANDIEYMTALQAQVLEVFKVVRTDIPGAASAVIIQLSKFVSMAFDMTDPTPQRKRTFVAMSKESMGILHHLVTQHADGQEIYASGAFATALAALAKPIALKYQFPITTKSLQPWKAAVNATLAILETTLPHLKEKSVPRAAFQEAWDTITEIANGIIGADLQHEQAPQDDRVVAADQQFDIDAFHRLRELVIPSLGSGAVAEKTRKAYVEGLFRVSIVHPPAPADAALIYRSDSQHTNGDSGTAADLGSLYKPGQGRTIDPPPTKRADMSFVCLDELFSLVAAHDDSHNKPSIVVLPPTPRLPPPMTVGPPPGTTSYGAGDNSEHALHVRLAQTTAPFLILRCALTIRSYVSDQPLRGHMPQPMSQRRELSRILRCLVDLKSEPGAIPDLDGVDSEALKHLLRLYPLLIKASQVAGTAGDDKTLALVGEALDAIGTELGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z589</accession>
    <name>A0ABR3Z589_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_005298</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF5">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045090997" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="10">
        <location>
            <begin position="22"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="11">
        <location>
            <begin position="29"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="282" mass="28913" checksum="867353DC816CA4A4" modified="2025-10-08" version="1">MKSFFSSALVIAGLAARTTRAEDIDSNLGAAGFLFPTEREYSASADTTAPCGSVAQVGNRTNFPITGGFVGLVDQEEAYSVSVSISYSSNPTSLDEFETLIASTRIKDLYEGHTCVTIPNPPSNISVGDVATLQVSFEAVWDGSTTNETYYACADIVYILDADFTENDYCFNATIGGPSTTAAAATSTATSTSASSSGSSGSSGSTSGSTSSSSSKISKGAIAGAVVGSVVGAALIAGALMFTYRLGKKHQREAMMRVHMNTMALGDMNKPAAAAGSQASNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Q9</accession>
    <name>A0ABR3Z5Q9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Beta-mannosidase B</fullName>
            <ecNumber evidence="5">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Mannanase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_005531</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="18">
        <location>
            <begin position="30"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="15">
        <location>
            <begin position="202"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="17">
        <location>
            <begin position="702"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="16">
        <location>
            <begin position="814"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1894844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="887" mass="99969" checksum="73160A285616D8AD" modified="2025-10-08" version="1">MTRTRTDVTKWQWRLASTNDHDEAVTVAKEHSSLSQWKDVASFPSVMQMELQTAKIIPDVNIGENERLTQWAGHADWEYQATFPASTSTEGEVDLVFDGLDTFATVTLNGTTLLTSDNMFVPQRISVKDKLKDGDNVLRILFESPYKKGTELEDQYGVRPALFRDARRNHIRKAQYHWGWDWGPIVVTAGPYLPVYLDSYKARIDNVYVRTTKLADNHKSATVAAAVNIVGSGDQSADVRILDPAGKELAKSTVAFTDSTATATFDLTDPQLWWPNGQGEQHLHSLEVTLSESQDTHNSRFGVRTIGVVQEPLADGEPGSTFMFRVNGRDIFAQGGNWIPADTLLPTVSRQRYYDWVQNARDAHMNMLRVWGGGIYEHDDFFDACDELGLLVWHDYGFACTNLPVHGSFLRSFEKEAAAQTVRLRSRASLAILCGGNEDFMLLDWEKVEYDHGNTKGPFPAGGAFPQRAIYLEILPKLAARLASETFYWANSPWSPGGLEANNLTRGDVHQWSVWHGEQKPYQEYKQLAGRFVSEFGMHGFPVQRTIDYFAPPTGKKGEGRHPQSRLIDCHNKGHGAHTRIARYLAENFRYDMASLTNFAYSSQLMQSEAYAYALRDWKRMFGGRSESGVSKARCAGSIIWQLNDDYPCTSWSLVDYFVRPKPSWYTVRRLYAPISVASERSPLSRFVDEDDPRAASQPPSFAIFAHNTTPKSAEYTLSLQAYDFWADKWTSLSDSDANRKVTLLPGQNTELGTLAAQSSWNKDSLIVLELSLKDDAGKVIARYVDWPEPYRYLEWPDDTKLEVKVKHASDSKDGVDAHVTVVANQPLKGVWLEPVYDGTEADDSFEPRWEDNMFDLMPGQAVTVGVSGLNGRDIKARFLADWEVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z756</accession>
    <name>A0ABR3Z756_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053949">
        <property type="entry name" value="SBE2/SBE22_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF15">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 12 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22874">
        <property type="entry name" value="SBE2_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="492"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="766" mass="84109" checksum="260A2CDE8FEE68CA" modified="2025-10-08" version="1">MMVYEHAIVDSVVPSPGSPPGMTASKSSKSSSFHSISSDDNSVLSDANHFEDIGLDDDAASIAAHHDRDQSDFKSRPNRFSPSFSADLRAASLQSASTHSLALTNKPRVFSSTRELARTRPHVAPPNNRDITPPVRPSFPSLQSQVRGANVRSTSTSALMPDALAPKSKRSLGSRSATSLSFRHRSPSPNLVNVPHGLKDQAAIVKPRRSSWQSTRERKTAIQLEMECDEDEGDDIPEGLILDNVPISPRPPSERSHSINPSPASSKPGSPDRSAKEHKHRSVGNGTPAIAAAQGSLRSPDWKNEHSKSYSEVSSPIKMRAKSWTTALSELSLEAKTLTEKLEEHADEVDLKTQQRSSTGSMPARRSSTGPALESKPRHKSALPELPPLRRSNIMIDPLPVSKEKEAVLSRTRPSWLPPKDPAEEKRHLKEYQKMMAYSLEAEKRREANKQAKSDCRDTAVSSLMQIWEHDIIPRWTVAIRERRTRDLWWRGVAPRSRGAVWSRAIGNELGLTEASFHAALSRAYEVEVRAKAENSIEGDEHYLACFKAIRKDVQDHTWKDLKIFQAGAPLHQGLMDVLMAYSMYRSDIGYVTGCNTIAALLLLNLPGPASAFVALANLLNRPLPLSFYAADPGAKSSAYNLMLQTLSQKSPVLFDHITNMPDHDPDFYLNSVFTSLFTGNLALDQAARLFDVYVFEGDTVLVRAGVALLVEREAALLGAQDMVAVVNAIAPGGDGAEDKQVVVAQHGEEDRWMLAVREAGKVSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z851</accession>
    <name>A0ABR3Z851_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Sste5346_004463</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 18" id="KW-0732">Signal</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106711" description="CFEM domain-containing protein" evidence="18">
        <location>
            <begin position="19"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="19">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="101"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="123"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="190"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1896830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="311" mass="26075" checksum="EE0D0E09E16F7DBB" modified="2025-10-08" version="1">MVSRTLISALAAAAVVNAQFPANFPACGTTCINNMAGQSSQLGCTSSSDYKCLCANQDFIFGIRDCSYESCGNDANAAEVVKYGVSLCSSAGVVVPTTTTTGGAGGAGGAGGSATTAGSGATNTGGAGSAGGSGSGSGSTTTGGSGAGGAGGAGGSGGSATSGASGAGAGNGGSGSATATGSGASATGTGASGSGAGGAGGASGTGASGSGAGASGTGASGSGAGGAGASGTGASGSGAGSSATGSGAGGAGGASGTGATSTKTGGAGGASGTTAAGGAGTTSSSTAFAPIVTAGPVGVIAAAAGIAAILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z977</accession>
    <name>A0ABR3Z977_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32980" checksum="913AD6A65D94004B" modified="2025-10-08" version="1">MTYESNGRPSTLTTCPPWIAAESKDRIAILRMLLAHGARSEAPDKGFERVGQTPLVDRPGGVGNALIQALTWPQGADVALVRVLVNEAGIDAHEGYFAATACFEGTGTNGLGEDAEADDEGWQDETELEAAQKAREAREADIPGTDFSTDLVAPSIPASFPTINTTYPYVSPQTGKRYHYTPLHLGARFDRLPILCVLLNRGANPSILVLYTGRSVFFSGFTSLLRLYSYTGRLVETNYGGAFNGPLYRNRVREIDVMGFGLSYAGPALLALGARPGARNNAGEIPTDGTSPTTTRRVKGYREFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9V2</accession>
    <name>A0ABR3Z9V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="15"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="609"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="611"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="661"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="748" mass="81125" checksum="3EED88637D52BFA6" modified="2025-10-08" version="1">MAREKKRGPKLPVQQLVILAMVRFAEPLALTSVFPYLPEMIKSFGVPKEEVAKWAGMTSAVFSVAQSLTAVPWGWTSDTIGRKPTIIIGLICTMICFIFWGSSTSLYMAITVRGIQGASNGNVGTIRTMVAEMVPQKALQPRAFSIMPMVWSIGSVFGPSFGGFFARPAEQFPGLFGNVTLLKKFPFLLPNLIACIFFIFSAVNAFLFLEETLEARKHKTDWGIELGERLIRVFRGGKPSKRSVMRARARARAEARAEARGRRLSFIDDEASAPLLSSAALQSESDLTLGASKPPTAFDDSNQLAKVAAAAVSSGATEVLGESCVKSTPVTARNPSIFTYQTSMALLCYTILALHSVAYDQVLPVFLNYPYESHDSSNTKLPFKFSGGFGLSSGTIGTIFTVNALVSGFAQFAAFPPLCTRFGPLRCFRYSCILLPFVYVLTPYSTLIENEHLRYAAFMTTFILKGVFSMVTFPCVTIILTNSAPSVKVLGTLNGYATLVSGMGRAVGPAMTGAAFSWGVQKGYIITGWFFLAIMAFFGAVSTFFLQEGDGIEVPTEVAGGEEELEEDQYDSESGGPSYSYATDDEDDDEYDYEESLLRDVAQDDDDYYINNISSRPHSSGTAVRGHHSRANSRHWSASNNDSPLPAPTTSRFSDNLLDSPASTVTASQTGLPQPKLSDLREPEDPESDDPDGSNATSLGLVDESAPPSPVRTRRFRSASTLSRPNRDGNGAAVPMSPVVPSTSERDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9W4</accession>
    <name>A0ABR3Z9W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-methylacyl-CoA racemase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050509">
        <property type="entry name" value="CoA-transferase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228:SF5">
        <property type="entry name" value="ALPHA-METHYLACYL-COA RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228">
        <property type="entry name" value="SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41524" checksum="A1D1B39F375B8173" modified="2025-10-08" version="1">MPSEPPLTGLKVIELAGLSPGPYCGQLLSSYGASVLRVDRPSAVPSHDILTSYKTSMVTDLKSPESLALLKTIIAKADVLLDPYRPGVMERLGLDPATVLLPLNPRLIIVRLTGFRRDGKYKDRAGHDINYLAVSGVLNMLGAKGQPPAPPANILADYAGGGLVAFVGVLLALLHRSVSGRGQVVEANMVDGAGYLGTLPRLRIKEPVWGGERGTNILDGGCPYYQCYECKDDGQYMSVGPIEPEFYKAFLHGLGCRYEDVVPSGLKREDKRAWPYMREKLTRRFRTKTRKEWEAIFDGLDACVMPVLGHKELESAGFEQRPLVGLVSSPAKPVDARWVGKTLPAGTGGEATLRDWMGWEHGRDYSISGNGAFMTPKKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9W7</accession>
    <name>A0ABR3Z9W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_004257</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342763" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="17"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="14"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="712"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="825"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="922"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1066"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="712"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="795"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="968"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="984"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1085"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1136"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1162"/>
            <end position="1171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1215" mass="129599" checksum="D029ED8128683975" modified="2025-10-08" version="1">MLVVLLACIGIQPASAVSVQFENCMPDDYVNNKDPVLLQWIPLYVEASFDTTTGDNRNLIVTMYGNVTGTRSSNPLPSWDSPLWNDTSDTDGKILREPDTTVATPKLTTLHSKIEVLTYEPWNNDTDFCATSLTNGVCPLGPVFNTSVIPYTDLPSVSMSNVFTTSYAFTSFSATFIIRYGDAASTTIGCVSATVTPSLGNLAWVIKFLPLLVLLAVGFATVFAGMYSPWGTADIFHWTSNYGRDPDLLRLVTPGFGDCLQYLQFIVLTGGLTLSYPGFYQPIVSQASWSTLMFNTTFVSKQTGIPNIVDGIYSTNGSYGLQNLGQLAGMGQVEDIWAGMMVWLLVIIAGVVILSQLGFAIQWIYRSVRRIPEEDLRSKNWPFSVGNLIRIVFNYFLLPLVSLSTFQFVVAPSSPDYTVALAAVTLAAILGFAAWLLYLIISTKPRAVLFDDLPTLLLYGPLYNTYSDEAAAYALSPFMVTLIRGIAIGAVQPAGIAQIILLAICEVVQIVTLQAIMPFHKQSSMNMYHTLFATLRFVTIMLMIAFIPALGVTEGPKGWIGYVILVIHAGILVLGFFLNAIQTLLEVIARMAGAGGDDVTGQTRGGLSKIFGMRQLSRRMPRRTAGAASRQSQMSSAGMLDSEEASKAGYVMPGGRLRSESAGSIGVLMNGKPGQRSSSALDNFSVEGGMAQAGRNLESGAGSYTPTTAGEMSNFSFLPSPNPNRLSGATGLFAGANTTPVEASDPYYRQPRRTRRPTVSQDNAPSPADRTRGSWASGDWGQGAVTPGGGPAPPAAAATGPNSNSAANAAAAAAIVAGGVPAITGDGDIEGQPSRGATPAPYGQPAFSPRTDYSTREVDFYYGVRGQRLNSDAPGRRLGTGPADPTGPMASAAGWFRTFIGGKTKEKGKGFEVVRSSRMPPAMVARGGDFEDEGPPPGIPVAMDVIRNGPIESDDEDEATAKNRRNIRSRDRPPGSEPKPAESDLLDEDGNPGDESETADEPGFLRVSDAPPLLPSIDGGDSIHMPSRLPSRNQSKASRYTAAGDGYNTGVFPPNPVPILAEVPNLPRKSSKRPISHDGKAQPVSHYTPSETGRTASVSSSHGGPYQQQPYLAPAIRVESTGSGGGLTTTRLPFDRNNSLQGRLSEGSSNAHTAEEFAQVDLNDNSSNNTGPGRGSHEDRPTSYGYVQQGSVNRIDPERQPDLLGASAEVVDERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCA1</accession>
    <name>A0ABR3ZCA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRISE-like Rossmann-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF8">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="1">
        <location>
            <begin position="7"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="397" mass="45292" checksum="EDEB080D7288EFF4" modified="2025-10-08" version="1">MASPKYALVFGASGVTGWAFVNEVLNDYPKKGTFGGVIALTNRPLTLEQSRWPKDDRLTIVSGIDLLQGSQKDLEKTMKERIPNLDKVTDHLFFAYKANTDDKVQNEENTNMFKRAVLATDHLCPNLETVVLQTGAKHYGCHLLGNRPARFVPPFAETEPFLEPPASEGLFYLPQMDFIREYSKDKKWGWIDTRPDIIIGFVPNQNFFSLGSSIGFFLSLYREINGAGAECPFPGTAKSWVAKSIDSSAEMIARQTLHVQLSDKYRFAKGESFNVADERTPRTWETRWPDLCAYFGLKGVKKAEDNPIEVRTYIRQNIDTWNAMEAKYGLQSGHADSPRIHPGFEYFLITQFDQDRQYDMTKMYDVAGFQEERDTTKAWGRVFDHMRAAKILPSEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCS6</accession>
    <name>A0ABR3ZCS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003718</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_bL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein L9" evidence="4">
        <location>
            <begin position="56"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="274" mass="29625" checksum="9F364668081897C7" modified="2025-10-08" version="1">MASLRTSTASCFGCIASRPLLASARPAATLSNVGISINTNQYRGKKTKQDGQGVVVRLLKDVTQFGRRDTILRVDRGRMRNFWYPRGMAEYMTAARIAELGPAAKIADLISFRDSSFVAEEDGVAGEEKIDTEAPSVSAAAHIETIIPASIIFYRKPISSETSAIFGSVSADDVANMVREVLLASQDEEAMLVRVEPRDVHFIVPESQKTEEGDSASTVDRIKALGRWEVDIVVRGSQGSNEPARRTRAAQEAAAAASSSVTVRKIVEVIAAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD24</accession>
    <name>A0ABR3ZD24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase ROK1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase rok1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ROK1</name>
        <name evidence="17" type="ORF">Sste5346_003452</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="281"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="560"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="378"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="732"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="180"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="788"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="809"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1898548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="826" mass="88732" checksum="3AED0F4DD2D42831" modified="2025-10-08" version="1">MDILKVLSRGLKQPNGSKQAKGNNNFLPAGAATLPSAGSSINPQLYHDRMASLIAGNNGSKKNRKRKRNGDSTNDSDDSQSGSDSDESDGSDDLNELDFFGERSAVATTTADNASSDAKDAKDTKKAKKAKKQKRDPADDLLDEDECRQILRSHRLKLTLLTDRRAAAEAAAEAAAAAVVEKLEKKKKKKSEKKAKRAEEEAAAAASKAAKDEAKKQFFSQPLTAFAQLRQTYNLSARLADNLERLLYRIPTEVQMASLPLLLDPALALSKTTLPGDAAAVATSTTAVDFMAVAPTGSGKTLSFLVPAINGILKRRAEEKEKAGGDKTEDEASGGHQKHDHVLDTIVVAPTRELAHQIANEGKKLTVGTGVRVVAMSKGMRVQADDGEEEGEEASDSEEEKDEEEDGEDDKSKPSKKATVTRADILVTTPLMLLNSLSRRALPTVRSLILDEADVLLDPLFREQTLGIWTACTHSNLRATFWSATMASNIEELVVEQLAARQTEEEQKRLLVRLVVGLKDTAVPNVTHRLVYTATEQGKLLAMRQLLHPSTSTSVTGTSGGESEALRPPFLVFTQTAERATALHDELKYDIPAAAGGADRLGVLHAALADTARSAVVRKFRAGQVWVLITTDVLARGIDFAGVNGVVNYDVPGSAAAYVHRAGRTGRAGRQGGLSVTLYTKEDIPFVKSVANVIAASEKQAAKSGGSSAATEGKGIQQWLLDALPEVTKADKKRLKTRGVESRRSTTTAGAAEKAKGKGKNHKGKSAGSRDSKETIPNAKARITSKSAWERRRDNNRRDAIASSKQRKQQGEKDGGSDDGEWRGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEH2</accession>
    <name>A0ABR3ZEH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003589</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF26">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="335"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1056" mass="110624" checksum="E5ACB63360824F1D" modified="2025-10-08" version="1">MDKPGADEALAQQYPTPSADGQAGSSSFYHGTGADVGLDQIDPQLEGMQTDESRGGGQLDDSVATTEANVQALVAAVSGSDDVDVNMGGGPDESYPESHLRALKTEDPGQHDDGSGGSGGADAYVDTTQSGHNSDENNMYAAAALEHVQQAAAAQQAESQQEGVAHHDHQQHQQPHEQDHNTGHDQHQQSVRPPVSVEELQLAAQLSQGLAPMMREANARREGEFHDVSSGVNNDVGSSADAAPGLHDGQDDAEALRVAAAAAAAAADNAYGSPDVTSAYHHTLQHPADVQGHANYGDASQGVSHLPASLQMAQIAQQYNVDHIPPRKRSKVSRACDACRRKKIKCDSVSETEQCTNCRRARTECLFSRVPQKRGPSKGYIKELADRINSIEGKLGNQSPSSAADALELLGRSGGDFSLNENAKRPFGSMSADTPEGSPATSNRHAAWATTTPRTTNLFQTPAGSAAAASRTSYSAVSLAPQPQIDAETPNALSRSLTDMERLLPLADHESQELDDAVFGSYLTAVHPCLPFLPSDRSRVLDNLAQCPQFLQDAFVVALRAVSDALGSAPTTGLARVASALLAQWETEGSPRTSLHDLVHLQTLLLLAVEADTHGPAALKGHHGGLSKTALLSRAVAVSYEMDLPKEQLGATAAAISAAAAEDPSQSEAVDTDSEARLGLRAWWSLVVLDRWNAVALGKPLLIPLRTVVLSPGLRPLLGESAFQFTKLSYLLGSSIAPALVSTDPLRQLQTSLSTPSSSAFLGPLGQQLDLGLEMWRADLPDAVTESAAPLVHLGYWQYRLLAYLLQPSTLSSDVSWATKKVVELTLVATDAKAVSRRGPSPPITPFHHYFICLSGLILAELSKVANERQGALRTLNDLLEVVAPKPIPIEGGAEGATEVPNSSVWNGPLRETLARRLKSSPSNASTNNSNNSAANATAVAAAAVAAAAAAAVEAVVTASEGNGADEASTELAQPAATPVLTPAPAPAPIVDDSVLRNATNFENLGFNPLALLRGGFLNTVHKTAVATPVVPATATPVAPEAHLEGTPVQQEAVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZES8</accession>
    <name>A0ABR3ZES8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Ef hand domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_003291</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="14">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="14">
        <location>
            <begin position="165"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="352"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="14">
        <location>
            <begin position="353"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="13">
        <location>
            <begin position="1405"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="113"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="425"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="507"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="872"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1012"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1066"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1332"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="750"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="509"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="570"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="872"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="883"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="920"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1012"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1085"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1125"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1147"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1211"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1231"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1265"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1366"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1399"/>
            <end position="1408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1898880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1447" mass="147382" checksum="C4AB3E3E16F92643" modified="2025-10-08" version="1">MASEGSDEVAANLNLTNEEKQVYGQLFRQADPESVGIVMGEVAVKFFEKTRLDSRILGEIWQIADRENRGFLTPAGFGVALRLIGHAQANREPSPNIALQQGPLPRFEGIATSAGALPSQGPLSATATGPLSAQGTGAGAQQLAAQGTGSGAGTASRVPPLAPERAAQYARVFQDQTHGEPVMSGETARRIFEKSGLGIDILGRIWTLADTEQRGALVQTEFIIAMHLLTSTKAGSLRALPNMLPAGLYEAATRGVAAAASGAGGNIGVAVGSPASPVARQQSPLGGGFGAGGIAPPPPTASISRQLTGQMTGHMRPAPPNFSNSPLGRAAAPAAPAAAPAATGSDWLITPQEKARMDPVFQNLDKTRKGYITGEEAVPFLTRSGLDEDTLAQIWDLADVNSEGHLTSDTFAVALYLIQQQRQRTDGSSALPAKLPANLVPPSLRSKTTTSPPPAAVAPTPPPPQPKSAMDDLFGLDSGASSTPSLPALAATPAGVSAAPAGLSDPFATASSPVQPSSPTRSPTVTNSFKPFVPSSSFGRSLTAQVTGDSNSSAPSAAARAAPAPPLPQQPTGMSTSSAAQNDLLGGDDGEASRGLSNDTAELANLSNQIGSLSKHTQETSAHRTTLQSELSQVNTQKKNFEQRLAQLRTMYEKEARDVRALEEQLKTSRSDTKTLQTQLATLEASYTDLQTQHQTISTQLQADQQENTNLKERIKVVSAEVNQLKPQIEKLKSEARQQKGIVAINRKQLSLGESERDKLKTEAEDLTRQNQDLARQIHNASVVSNASSASPSVASASGKNPFFRRTGSSDIMGVFSSPAQGSPSLPSASVAKPIGEQSFDDVFGPGPAAAPALVPAAPAAVAAIKPQFTGASTGSSSFSAVTAPTSETTTPGISRQGTDITQTAAPEPASQTSFLPFHSATTSPAPAAEAAVAAPPAPASVSSPAASVTSPAERASATASPVPVAPKEVPTSSPPAPEASSSNSAFGGFGATAAAATAVTAATADIAAASSTSDAASPAADADKGKSVWSQGHAAADSLSDPFTALDQQQDKAKEDFESAFASFKAARAAEPSGDDDAFEVKSPAGAAAATAPAAAKEEDPVNTDTSKAFANFHSEFPPISELNNDESDSDSDGGGFDDDFAPASPKNNQSQKAPETTPATLPEAANGKPEISKAASPELAKSTPAAESDIFSSPADVTPDVFSTPAPIPAAAPAAAPASSTNMDDIFSAPAASAPEPTPATAAAAAAPATIAPAAAPAATTASDDDFDGLDDDFDGLEEAREGSADDEFANANRSTLDDFQSAFTASPAGKQSSFGVDNSFDFSTLGASTASAGTAAAPSQGVNGTKAADPGDWFSFAADEAKPAATEAAPAAAAATESAGPSATTEDAARPATLSRLDTQNSTNDDPILRQLTAMGYSRSVALSALEKYDYNLDRAANFLASES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZET3</accession>
    <name>A0ABR3ZET3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="308" mass="32241" checksum="19D88F5818EC10DD" modified="2025-10-08" version="1">MATATAPDLSSLKDTTVIITGGASGMGLATTLEWAAAGAYVTIADVLEDAGQQTAADLTAKGQHVTFVRCDVSDWSSATAAFKHAIAFGVNGGLDVAALFAGVVGDAGNLTDQVIAAKKATNSGDDPVCPRHVALEVNFRGLYETAWLALYYMQGAQSEGDNLSPTKSLILVGSLGSYTDSPPYSDYNAAKFGVRGLFRGLRHSTPSIGVSLSLLAPWWVDTPMVRSQMALYEKDGVEPGKGMTFTPMHHVVNAASRCAVDPVGMSGKAILVEPEGYMDFQDDEGGKWGGDVLAAAWQRSRAAGDRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF11</accession>
    <name>A0ABR3ZF11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pro-apoptotic serine protease NMA111</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pro-apoptotic serine protease nma111</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclear serine protease which mediates apoptosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ-like" evidence="8">
        <location>
            <begin position="463"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ-like" evidence="8">
        <location>
            <begin position="946"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1100" mass="119963" checksum="F6B7890202DE03A9" modified="2025-10-08" version="1">MNGSTAAASRPKRKTSYTVDQDRPSKLPRSANGGSGSGGVVPVADTPEDDAMLDDGVEGDDVDEAGSWASDEDGYRDDDSTAAADVAEDGASSNPSSSNENSGAANGRHRRHSKAATLQKQLSSAAVPPAVLLASGNAETAEWQETIQRVVRNVVSIRFCQTCSFDTDPALTSEATGFVVDAERGYILTNRHVVGSGPFWGYCIFDNHEEVDAYPVYRDPVHDFGILKFDPSAIKYMPIESLPLSPDLAKVGVEIRVVGNDAGEKLSILSGVISRLDRNAPEYGEGYSDFNTSYYQASAAASGGSSGSPVVNIDGKAVALQAGGRADGASTDYFLPLDRPLRALRCLQEGKPITRGDIQCQFLLKPFDECRRLGLTPTCEAQMRAAFPSETNMLVAEIVLPQGPSAGKIEEGDVLVKVNDELLTQFIRLDDILDSSVGQNVKLELQRGGETVIVNVPVGDLHSITPDRFVSVAGASFHNLSYQQARLYGVACKGVYVCEASGSFRFDTSDSGWIVQSIDQKKTPDLDTFTKAVQTIPDKSRVVVTYQHLRDLHTLHTAIIYVDRHWSSKMRLAVRNDVSGLWDFTDIGDPLPATPPVPRTASFIQMKHMPHPAVADLVRSFVHVNCYMPLKLDGFPKNRKWGMGLVIDAEKGLVVISRAIVPYDLCDITITIADSIVVEGKVVFLHPLQNYAIIQYDPSLVDAPVMSARLSSEELSQGAPTNFIGYNRISRVVHAATTVTEVFAVAIPANPGAPRYRAVNVDAITVDTNLSGQCGSGVLASDDGTVRALWLTYLGERSPSTHRDEEYHLGLATPTLLPVIEQIQRGVVPKLRMLPVEFRAIQMSQARLMGVSEDWIKKVSVANTAQHQLFMVTKRTFERNQDKNGHNGNKGLKEGDILLTLNDRLITRISELDIMYNHEVLDATIVRDCNEIILNLPTVAADDHETDRAVSFCGAVLHRPHHGVRQQISKLFSEVYVSARTRGSPSYQYGLAPTNFITHVNGKPTPDLDAFLAAVKEIPDNTYFRLKAVTFDSVPWVVTMKKNEHYFPTVEWIKDKEVPCGWRRVTYEGGGKVVDGEPAEGVVVPAVEDNGDIEVAALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFD2</accession>
    <name>A0ABR3ZFD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GDI1</name>
        <name evidence="3" type="ORF">Sste5346_003012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="464" mass="51160" checksum="452D220779C0110E" modified="2025-10-08" version="1">MDEIAKEYDVIVLGTGLTECILSGVLSVKGKKVLHIDRNDHYGGEAASLNLQALYKKYGNFASGEEPWTKYGRVNDWNIDLVPKFLISSGELTNILVSTDVTRYLEFRQIAGSYVQQSNGPKATVAKVPADAAEALRSPLMGIFEKRRMKSFIEWVGSFDINDPATHKGLDINSCTMKEVYDKFGLEATTKDFIGHAMALYLTDSYINTPGAAPEAIERIRLYGNSVARYGKSPYIYPLYGLGELPQGFARLSAIYGGTYMLNTNIDEIEYDNGRAVGIKATMANGDDKVEFATKAKFIIGDPSYFPDKVKVVGHVLRAICILKHPLSNTNDSDSAQLIIPQSQVGRKNDIYVACVSSAHSVCPKGYWIAIVSTIAETSANHHLELQPGLDRLGKIEEQFMGAPIPLYEPIENGTADGIFISKSYDATSHFETTTDDVKDIYRRCMGEELVVEGLREGIQVAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG62</accession>
    <name>A0ABR3ZG62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="401"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="49402" checksum="9DAF678D9512D409" modified="2025-10-08" version="1">MRRIAIVRILLAHGANMQVPNKSFERVGQTVQGAFDTSIEHGEREGNLRPLVYRPGGIGNALIQALARPEGGDVRLTRMLIDEVGIDIHKGYFFATAAFDSRGCNGVADDVDDENVKLDMDAEFKKYKAMYEVDPVAVHAANKAAVNAAAAAERLLKGPGQGPDTYLTPLAAAALFRNAAGIPETMLNAKNGVDGNDGNDGADATTTAVLAETTAMRPLYAVMIGRRYEFKRAPFFREPELYRDGILYREAGANDDRAAVRKRDGLPDELLEKQLEIQADKEIADEDTLHPWARAAHQTEAAQKAYLDDCVATVQLLTADRAVCAATINATHPYNGLLYIPLTGRCDCGGGGLSPPSYRPEIVAIDASIGAGGMTLLQRDLLGPDTDDVERLARIHEVDADGNTALHWAIGYNLPHAQAALLELGARSDARNNVGEVPRQGTPPTTTRLDKYARHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGQ0</accession>
    <name>A0ABR3ZGQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit H</fullName>
            <shortName evidence="4">eIF3h</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EIF3H</name>
        <name evidence="6" type="ORF">Sste5346_002987</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08065">
        <property type="entry name" value="MPN_eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03007">
        <property type="entry name" value="eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027524">
        <property type="entry name" value="eIF3h"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="372" mass="40992" checksum="A3F890FE9BBC7EDF" modified="2025-10-08" version="1">MVTATDASKDLPFQAVQVEALVVMKITKHCSSAFPTTATGAIVGMENNGTLEITNTFAFPSVADAAVDSGANDRGHQNDASAIASAAPRAKSNITYQAEMIRHLKEVNVDANSVGFYTSATMGNFINMSFIENLYHYQRDAQTGAATVALVYDVSRSSQGALNLRAFRLSNTFVAAYKEGKFTTETLQKSKLSFKDILVELPVSVHNSHLLTTFMHQLPSPPAEAEVELPASLSDIHRAPMAIPAYPSLDALDLSIDPFLEKTCDLLLDSVESHYTDLNNHQYYQRQLTREQQKITAWQTKRKAENAARAAAKQAPLPEDEWQRLFKLPQEPSRLEGMLNARQVDQYSRQVDGFTSSVSAKMFAVRGNLLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH96</accession>
    <name>A0ABR3ZH96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF27">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35094" checksum="6AEDD98039AC7129" modified="2025-10-08" version="1">MAKLLPLAGGDYYAWKYLPSLPASIVFCVLFGILTIAHSYRLYVNRLWFCIPFVVGGILEIIGYAARAVCYYNTDKLGAYIVQNLCLLLPPALFSASIYMVLKRTILAVRGSHYSIIPVKWLTRLFVIGDVFTFWVQGGGGGLMASNSLANTGEKIVVGGLVLQVILFGLFCATAITFHYRFKTHSVGAVSSSGAAIPWERILYMLYGSSVLIMVRSIFRVVEFAMGQNGYPLSHEWTLYVFDTVPMFIVMVIFFVWYPGSLDPSASDSTHGRDAENGNIRDVNGDNWHGSGGTETDASQDNRYVQMEALKPNERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHP7</accession>
    <name>A0ABR3ZHP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002506</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="288"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="54709" checksum="62C85F5441C476D0" modified="2025-10-08" version="1">MARPHHGWSQDPYAPRQSSDHRAYFSQQDAGRERVQLPGPSSLFSAAAAAATSSPSSISSPHMSSHPPPPHASAGRDSPPYSSSGRPSSYYGGDYATPSPVGQTPPQLPAPNMDSQSLPGPLALRTTVRGPDSRFSPTQSPVSSVRSDDFDLGPRYQQQAFSHLPTTPRYRSRDPPAYHHQPPAPTSSPPNVSLHHSKAAAAAAYPTPNSRSIYPPMHPASPPSGPGRLPAASTSPRTEAKQISITSLLSEESAPRAAVPQPQTPYHHSASTASTTSKTPMLSPAQSVITSEYRIHVRQQPVAARSCGFGERDRRVIDPPPIVQLTIDDPEATPEEISMRLRFQFTVLHCSIWNETGEQDNSAMPEDYRQQRRLMGTLVSSPFVGQDENGVEGCFFCFPDLSCRTPGSFRLKFALVVLDPLGMRAGGSSPIMATAMSDVFTVYNAKDFPGMQASTPLTKRLKEQGCLISIKKGNDKTSAAHGREESEEDDEGGDGAPAGKSRKRAKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIN2</accession>
    <name>A0ABR3ZIN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208324" evidence="2">
        <location>
            <begin position="21"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="174" mass="16112" checksum="9C75E806C3025E75" modified="2025-10-08" version="1">MRASNTFALVLAAAASGVAADFLSDVTSVFGDVTSGAVSVATDVASHARSAGTDLASHATSVFGDVTSGAASVATDVASNGKSFGSEVASDARSRASDARSVISTGLHGTGGGSSGTTVSGSDTSLATATQTDGTTGATGTGTGAAATGTNGAGRAVPLSGAAALVVVLAAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIQ8</accession>
    <name>A0ABR3ZIQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitinase 2</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CHT2_1</name>
        <name evidence="3" type="ORF">Sste5346_002264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045791650" evidence="2">
        <location>
            <begin position="20"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="369" mass="31605" checksum="67C99CACE582760A" modified="2025-10-08" version="1">MLCQHFGQLFGALVAELHALPTGPSTGPSSSPTGPSTGPSTGPSTGPSTSPSTGPTGPSTGPTGPSTGPTGPTGPTGPTGPTGPTGPTGPTGPTGPTGPSQTTGPSGSTTLSTVTTTITTPCSTDIITTFLSTSTVYTTTCYVVTSCPHNGGHCTLGHTTTQTISYTTTVCPITTTIPAGGSGGGGHGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSGGSSGSGGSGGSHGGSSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSNSGGSGSTTTSSGPATVVTAAAGRVVSPEMFALIPALVAAVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIT2</accession>
    <name>A0ABR3ZIT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="46"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="233"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="353" mass="37771" checksum="2F1EB923748EF953" modified="2025-10-08" version="1">MSAPADNKVSDAAVNDVTAALASTAISGKPDEKANEAYLASAAEGRRLYIGNLAYATTEGELKEFFKGYLVESVSIPKNPRTERPVGYAFVDLSTPTEADRAVTELSGKEILERKVSVQLARKPEAAGEKEATNGEGEEGTRRRQSTRGRGRANRGRGNRGRGGVNEDGTPAEGEAASTEAAADAAPKDVTNKPAATEETGKKARQPREPREPREPRERRERGPPADGVPSKTKVMVANLPYDLKEDALKDLFAAYEPSSAKIALRPIPRFMIKKLQARGEARKGRGFGFVTLASEELQQKAVAEMNGKEIDGREIAVKVAIDSPDKTDEEANAPEGEANGENVEAETPAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIW9</accession>
    <name>A0ABR3ZIW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002378</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="499" mass="53292" checksum="231597686DB6367D" modified="2025-10-08" version="1">MAPACVKALKAWVEPRLPRRLRAIPLPALALITLLILINLIVWAVVGVILRFYPALTGTAVLAYTLGLRHALDADHISAIDLMTRRLIASGQRPVAVGTFFSLGHSTIVIITCIVVAATSGALRERFNGFERVGNIIGTSVSAAVLLILCAGNAWVLWRLVRGLRAELKKETLRARHAQDGDEEGAPAGDRSSSGEHLEPYRDNVENDADAVAEADIHENDNNSAYGQPGAEQRQTGPHAVAEATAGDAMNNSAAHLKLEGGGFLVRIFRRLFVLIDRPWKMYPLGVLFGLGFDTSSEVALIGIASIQGAKGTSLWLILIFPALFTAGMCMIDTADGALMMALYTSKTFSRDTVAILYYSIVLTGITIVVAAFIGFIQLFTLIDNVATPTPTGPFWDGVGAISDNFEIVGGSICGLFVVAGLGSVLVYKPWRRRMDRRLAARAACLSLEEAQAATVVSVQPEPPAEEPPKVIAEPAGKSGSKAQQTVTAVEVVGESSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ40</accession>
    <name>A0ABR3ZJ40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF102">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29212" checksum="F1AEC81AB44955EA" modified="2025-10-08" version="1">MDTQEQNRLDLQHHLATRLLEGKLYLAPIGNVNRVLDFGTGTGIWAVEFAEQHPEADVLGTDLSPIQPEYVPPNLRFEVDDVEDEWVYSAPFDFIHGRYILPSLKNPRATLQRIYDFLRPGGYVEIMETLMVIEAIDDSLRNTVLPRWHTLILDGVRKMGRGDPMVPLKTKQWLTEIGFVNVTEKKFAVPANGWARGDEQKIRGHLMMTNLLEAAQGITMSICMKVWGWSKEEVELFLVDVRAALKDRAVHGYVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB9</accession>
    <name>A0ABR3ZJB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="3 13">2.7.7.79</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">THG1</name>
        <name evidence="16" type="ORF">Sste5346_002471</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="3 13"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF6">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028980">
        <property type="entry name" value="tRNAHis_guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="14">
        <location>
            <begin position="6"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1 C-terminal" evidence="15">
        <location>
            <begin position="150"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR028980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1900161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="302" mass="34343" checksum="B5A4B3125E93336B" modified="2025-10-08" version="1">MANSKYEYVRLFEQPDTLLPNTWIVVRIDGRGFTKLCAKYGFEKPNDKRALDLMNAAAKAVMADLPDVVLAYGVSDEYSFVFHKTCQLFERRASKLVSTVVSTFTAFYLHLWPTVFSAAPEGTGLVDDVPLTAPLLPTFDGRAVCYPSVQNLRDYLSWRQVDCHINNLYNTTFWALVQKGGMDSVEATELLKGTFSADKNEILFSRFQINYNNEPEMYKKGSVVFRDYELVDPTSTNVAKTTEVADNQAEPPTLSKSKVESEKKRRAKARITVEHIDIIKDEFWDRRPWLLTGQPGTLPKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJX8</accession>
    <name>A0ABR3ZJX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF5">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="46"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="454" mass="49005" checksum="EF8B2628DF76551C" modified="2025-10-08" version="1">MSDTLRFVGFLAAYLPGFAGAALVRKIRAIIHRWTYKGPTDTPKIVLVVGGSFAGYQLMARLTETLPTGWQAVLVEKNSHFNWSFAFPRFAVVPGHERTAFMAYAKILAKGAEQGIARFVQGQAVSVTADKKVLLASGEAVAYDILVVATGSQQRPPAKLLGSTEKDTACSELQLLQDRIRRARTVAVVGGGAVGLELVTDIKTYASVVAERHRAKLVGDGKEGDEDDSVADKDVTLVHSRTQLLNRFGKRLHEHVAGVLEKQGITVELGQRAKITYKEGEDSEGGAGTLTFPDGRTKEYDCILLCTGQTPNSALLQDVYSSTITETGEVRVTPGMQVVSTDGKTNTTLEDIYAFGDVAATGGPKMARAGFFQADIIADNIMDSVKNKPASHKYVPSIVEPSLKLTLGKDATVVYMDLNAEGTKSILMPKGGDAEDMYVKQSWGFMGVKYEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK13</accession>
    <name>A0ABR3ZK13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 10">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_002127</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="12">
        <location>
            <begin position="16"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="11">
        <location>
            <begin position="142"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="332" mass="36803" checksum="9ED898CFD8EF4C34" modified="2025-10-08" version="1">MASWVDVPEGCDFSLANLPYGIFSLKNTSSNKNSDLRRICTAIGDCVLDLKGLAREGLLVSLGFDVTTLEAETLNAYAALGRAVHRRVREFLQDLLRADTVLGEHLRDHGDRRQRLLVPLADVTLHLPMDVRNYTDFFVGIHHARACGRIFRLSSALTPNYEHIPLAYTGRASSVVVSGTSFHRPNGQYLVDGKPVFGPSQRVDFEVEFGALIAQGNALGEPVSIQEAEDHIFGFVMLNDWSSRDIQRWESQPLGPLNGKNFCSTISPWVVTPEALEPYKTEPVLTHNSVLPYLEENSDKTVYDIPIDASIISMSLHLPLSLGFQHSSGILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK1</accession>
    <name>A0ABR3ZKK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetraspanin tsp3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36190" checksum="BFDB7A2DE8213010" modified="2025-10-08" version="1">MATWSWIYVYPVLLVILFGVAIYEHVFTTSLSLPLSPVLTVLAIVLPVLSFANTIALPAALTATDNNDSLTLVLTRRRPLLVASLLQGFHLIQLLLAIILAVFFFERTAPSSIRSCLLGTAWQHLFATKNAAALRRIQDALDCCGFNSVRDRAWPFAEHVGRGGGVACAERFGRTQACAAPWTAALQRTAGIEGGIAAAVFLLQVALYFAAPWVNAQQQRRQQNRPQQQRESGWARLFLPFVAGGVRGEETDGSQRPLLGSGNDNNGRGYVYEENDNADEQPNGQEGNTEGNENAQNGDIVDEEQARPGEQEGQQSTGQYGTIAPHDAWRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLC5</accession>
    <name>A0ABR3ZLC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Jun-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SRP40</name>
        <name evidence="3" type="ORF">Sste5346_001930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007718">
        <property type="entry name" value="Srp40_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05022">
        <property type="entry name" value="SRP40_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Srp40 C-terminal" evidence="2">
        <location>
            <begin position="457"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="528" mass="54921" checksum="242C65538EA31995" modified="2025-10-08" version="1">MPGAPPAWLFSSKPAAASASTTITNPTTTTNTTDTMAKTDKKADKVSKKDSKKDSKKESKKSKDVATPKKGGAAAAAASATSPAPQLLDLVESFLTQHDFSQARDAFKEQREKNGWPASPAVGATGASLEGVFEKFQSTTVKKEDSSSSDSDSDSDSSSDSGSESDDEKEEGDVDMKDAESDDESSSSSSSSSSSDSDSGDEKKTKTKKTKAKAAPVPVIVAKPNPLKRKASSSDSSSSSSSSSDSSSDSDSDSDSSSSSSSDDGKHKLKKAKLTKKEESSSSSSENSSSSDESSSESTSDSSSDSSSESESEEEESSSDSDSSSSSSSSSSSSSSDSSSDSDSDSESEDEKAAKVPLPESGSDSSSSSSDSDSSDDDKKKSKKEKKDKKTKKEETAENGSDSSATVVGQSSPAPTGTEPKFPPFPPDPALTLKQNNRNRAASKAAAASGGPKQGERFSRIASNTYVDPKFSSNAFELNGHHWGQKAHEDLIVTRGKGFTKEKNKKKKGSYRGGFIDTNARGGIKFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLI6</accession>
    <name>A0ABR3ZLI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF7">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="173" mass="18809" checksum="625D05E32300F860" modified="2025-10-08" version="1">MVAEDTKKTNAKPTKLLDLIQSSFSASNLMPTKLHIDGLAISKDGETVLEEYFGDMAADALHIISSCTKSITVLLARIAIEQGLFGLGDKIVDYFAGVKSKWSSDDDKLPMLTTDVEQLVLGWQLVASLGAPYNYDNGMPSLIGCLIERTSGIPLVEFANQHLFAPMDITRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMH1</accession>
    <name>A0ABR3ZMH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi membrane exchange factor (Ric1p-Rgp1p) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RGP1</name>
        <name evidence="2" type="ORF">Sste5346_001812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08737">
        <property type="entry name" value="Rgp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="971"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1119" mass="118645" checksum="7EAD59C116060AF0" modified="2025-10-08" version="1">MARDMGFGQGNGGSGPGSSSNIRVSVRWYENTIFGGDDVRCRITFSNVAPKPQPMQPQQSSSQQHHLQPASSLSSASSSRHPSNSYHPERARLPSSSSSGTLAPPAPMGRGHHRASHSISGPATGVITSVSSTSASAAAAASRRRADSIPWAPNGSAGNSNGHGSGNGNGNGNNGAGNGGSSGGHGHSHRRSLSIVSISSAGASDGPSGSPTGSPQLLNGPASSQHRPVRGHSRASSLQIGPRGSSYYGGPRSATNPPRPYSNQPSPLFNSSFPPSASDRSGNITGLRGGRLTGSATMPNTPSVGGMSRSPRSPSDGFSDFKFPMAPPPTTPSNPQGPIDGPVLASPTPMTPEDKPLPALPIRSRDGPSNNINHNNAGGAQSAQVPTIYEGPVTPSEARVLSTTSIAGTPRSSGEFYSLSNHSTETLASEYMSQQPLRSQPGRPPHTRQKSSSNLLSPPMHSQQQLSHQGHHLSRSLSQRARTSAASAAAAIAPETLMMGYAQIEGSFTLDGSLVDLSPFEQVKRKGVVGGQGGGVVGLKQNKRDSGLLRGFGWGSLATSIGDLLGGGELSTIKEMRDKASSKSVPLLATQQSVLFADLQLAPGESKTYEYVFQLPKGLPPSHRGKVMKISYSLVIGTQRPGTAKEQRVNSIDFPFRVLGSVNGHGEILGHNLMSPYSPETSSNTATVRTVSEKELSRPWTLTPPGAQKQQQLPPQQLATRRRRSSTAATITGPTMNGFMMYVDELLKQREAESQADAASANGFFGAASAGSGDGNPRSGLLSPTAILPGSRRMSTASSIFLPDDNGRPLLSLSCREAIELAIMRSNLTDRNPYGGGGGSNVSANRFDISRNKLKVATVMLARPAYRLGETITMVVDFANAKIRCHAVHAALETIEKIVDPKLALRSEASVQRASRKVYASLSEATLYSRRFVFTATIPSNATPEFETTGVVLEWKIRVEFVVPAEDETDLHNHFANGNNDNEDYYERDDHEDDIQEEDDEDDDGEDDGSNAYGEEENDVTDDGSSSLSSRRPRRLLRQRSSHSAHNRQLRQNQNQNRATPPPPPMLEEISRDDRGGLVLAAVEALRCESFEAAVPIRVYGWSGDFGGSGEHDTREKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN21</accession>
    <name>A0ABR3ZN21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gag1-like clamp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053274">
        <property type="entry name" value="Fluconazole_resistance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065:SF1">
        <property type="entry name" value="DUF4050 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065">
        <property type="entry name" value="FREQUENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gag1-like clamp" evidence="2">
        <location>
            <begin position="277"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="700" mass="75073" checksum="AF9F25B53C9AAEA8" modified="2025-10-08" version="1" fragment="single">PAHQQDEQNQQIQQDLQNPQNPQKPSLKYLDQPAPARAPLLAPAPDAIQNFTHQHQRNPAQALASSELASMPKMVFSDLIKSPKSPFAKFRHLHTGSQQHNTTQVEGQQSSELLDYGDPDLLSRDKTKQKEAVRRYLADKIRNDWDFSWPSPDLSTAHTDAAQARALTVRKRLVRAEQVGLLEPSETFASPLPTVGDSATVSLAAVSAAVAADAAAEATAGDEPNFDDDFESDAESVYSTVSEDAIHFRPRAEWMSDLSEDEKPGTYYSRMPTYVHSPFRFDSPDAVGTAVNVPVDVRKANARRDMRAEIVWNEGLACFIARRDAWTGARTVHLKPAKPLAPTSPVSPRRGLFRFHSHTKSEPAPAVSVPIAIATGGKAGTHDSHSASTTPTAPTQTSPTGRTSTTLPLSPVTSNSRHSQHSQQSHHSQQSQQSAGLDTVATTPMTSDCGGGGGVDGGMLQQSVSHASAKSPKLGLTRSHASRASQPHPDYAVETIIPVAPPLLPPGNPMRASITPAIYLSLYDKLVSSSLQPSCPINLSDMIRSCVSGWKRDNEWPPRTVEMSAPAVAAMSIALRKKRRDERREVQKDKRDTTNHPADGGSSGLPSPGLTRRMSSFLGGRPSPGNIVLPTTTTAVAGATGPASPPIDEKDSSDGINGQRGIRRSLQRVLGLGYAAHGGNTGGHGHSMSVGTVGQYTKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP04</accession>
    <name>A0ABR3ZP04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001414</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="112"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="597"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="633" mass="67830" checksum="EDE68369A87481F9" modified="2025-10-08" version="1">MEPPEPSGRASWKARDYHQSLRETSLVGDTFYGPGDLQKKQKQRPDTPDSEDLSVVSTETRREVLGSTELYENGQLRFIPMPTPDPKDPLNLPNWKKWVAIIVMCLFGSLGLAAEVVIGSLLPVFLLEYSGVDPVAILSDPALAARVAGGDPLSVLPPGVTSKVSLAQVSLLATVPQIANGIAGYFLIPLSATIGRRPVLLITAVAAWAGGFWAASSQSLASHIAARVVHGLGAGAVEALLPLIVQDMVFIHQRARATAAVIASQGIFIVILGIVGPYLAAHFTWRWVYWITSALGVIVWLLIFVFVPETLWTRSPEELSGQKVYPLAHGEMRPRLDPENYGGPRTRWTDYGVLQKSVIPKDWKRSGLVALLDPLRVSYYPAVLLIVIINVAFMLAISTTQQAISFALLAAGIPFQWTGISGLPSVVGIGFIYLLGGVVADKIGLAITRLNGGRREPEHLLPNMALSFILGIAGCFVFGSAAQGAGPSSPSSVSSVALLLFGNFLLLLGSLTLLTTTNVFLIESYPQRANSVIVSASSLKIIATFFLATNATTWLQAMGAMKLYAAFAEMLLLVSLGLPLLFVFGKRLRQWTSGTVEDRSLKSKNGRGKGVSKRSRPSSDASGDDSMSGGGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ7</accession>
    <name>A0ABR3ZPJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Accessory factor associated with RNA polymerase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC73</name>
        <name evidence="6" type="ORF">Sste5346_001062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="5">
        <location>
            <begin position="246"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="423" mass="46188" checksum="AEEAED93AA2DAAF2" modified="2025-10-08" version="1">MTTVDIDPLLFLRQAIAAGSPVVPTATDVADAPETPLPQARFLQFASAASDRTAVPIDAPTRFVSNDAAVDLRSIYFAWLNREVAIHEYNAAATRLNEELASVGSTATVHKFAFVERLDLITWLEGASEESEYIKAVGGAGVADAAGAAAGARTDAGAAAQVSRAGRGALIDPRLAEIYSGERRTGDHNTVLRGIKPTDFSHVRKLAVPFMSRKQGGSAPAGALDPAKKLPGAALPLNQKGGPNRRPDPIILLSPSASSLLRMSNIKSFLESGRYTPADNSSTATMLHITRTVKDIDPQRPIRFILVEGPEHFKPEYWNRVVAVFTTGQAWQFKSYKWNTPAELFKHVQGVYVGWRGEPVPQGVRDWGHRVLNLNIDKYTDPSLPGADVNRWRDREVAENIWKAIEHNMRQKGWKRDSGATLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPT7</accession>
    <name>A0ABR3ZPT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L9B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL9B</name>
        <name evidence="5" type="ORF">Sste5346_001561</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="98"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="193" mass="21880" checksum="BB7849EE24DB469F" modified="2025-10-08" version="1">MKYIHSEEILEIPEGVKVHIKSRLVTVEGPRGKLTKDLSHVAVNFSLPKKNVIQIEIHHGNRKNVATLRTVRTLINNLIIGVTKGYKYKMRYVYAHFPINVNLDKNAETGLHEVEIRNFIGEKIVRRVVMQAGVEVEISKAQKDELILSGNSLEAVSQSAADIQQICKVRNKDIRKFLDGLYVSEKGNIVEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQC5</accession>
    <name>A0ABR3ZQC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol-3,5-bisphosphate 5-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FIG4</name>
        <name evidence="6" type="ORF">Sste5346_001256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="424"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="934"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1030"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1180"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="934"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="957"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1180"/>
            <end position="1205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1422" mass="153524" checksum="FF6DE5796C915E85" modified="2025-10-08" version="1">MAVLNSTVDSPADAASLASSQSTTTLPATSSGDATTTNTSTNTTTHHSSNNIPSNQPFPQLRNNAGADADSDVDPETLGEGVASLTKTLRMTKVAEAVTGTGDDNDDDEDPAVARPFLRTASPDNGKGRTGGGDEDDEDDDYEEEGDEDENGEGDEAYTDEDEDDNDDEETLATEETATQSRASLNGADPDNTEGDASRKAGTSSRAGGDRARRRATAQAARAAKAARTARQAAAHERMGHKMHKFTLYETASRYYIVGEDVTGRRFRVLKIDRTTTTADDAELGVTDDKIVYSQKEMVQLLDTIDDGNRGTGGIKLRCTTWGLLGFIKFTGPYYMMLITKKSTVAVIGGHVVYQVAGTELIPLTPGRGASVGMSVGSGGGSGGGSGSAAGSGGGGGGGNDGSHSTSGHHTATHADEVRFLNILNHINLAQSFYFSYSYDITHTLQHNITQERAALAAGRRWSCDEAHNTMFVWNSHLLQPAVDALSSPFDWCRPITHGYIDQASISIYGRTAYVAIIARRSRYFAGARFLKRGANDLGYVANDVETEQIVSEASTTSFHSPGRRLFANPQYTSYVQHRGSIPLYWTQENTGVTPKPPIELNLVDPFYSAAALHFDNLFARYGGPIYVLDLVKSRESTPRESKLLVEFTRAIHYLNQFLPADKRIIHHAWDMSRANKSHDVNVIRVLEEIAETVVATTGFFRNGEGEGTGAVTPPAGTTEPTEEDVTLLNFSQQARVQNGVARTNCIDCLDRTNAAQFVIGKCALGHQLHALGILDESKVDWETDAVNLFTHMYHDHGDTIAVQYGGSQLVNTMETYRKINQWTSHSRDMLETFKRYYNNSFLDGQRQEAYNLFLGNYIYTPGQPMLWDLPTDYHLHHADPRRRQPGAGRGGRDYIHWFTPENLVQRTLPPLPALRAPINAHAYHTAMASAARRHKGTQLKFKRKRNGQPKFRRNISSRSANSSLLTTSSSLNSPLSTDDYWLEFYRPYFLSSFAKMFTYKIKSTMKYIPFKSTSAGQYDLSPFKVRSEIGSHHSSSGGGGGGGGEKGDTDSIASSRTTANSRRRGNGHRKEVSFATPHDVASARLSGGGADDAASIASVASGGTASGLRNWLSPSLGHDRGSDAAFIAGSAHVPSIQNQNHHQQQQGVHTLMKEGARPGSSAAVGGSMAAATTATTAAHIVSSPSRGSAASLASGGNGNANQGSTQGGRGHVRNNSSIATTLDTTMVANGGLLFEADPRQKAKQSAVDKARQAQLTFAKMVQDSLNPSVQETEDYERYISHPQNLQIVVSTDEAVNANVSDAISLSGGRSPATGISAASNEEYQEYVNGTWKTDGLGMTFPEPTTATSTSTNFPSAALASSIPSLPGLDHLDDELAVYGELLRVPENPLTVTEGDAQKKRYKAYRKWLRGKSLFKQQMVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR37</accession>
    <name>A0ABR3ZR37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="376"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="569" mass="60080" checksum="AE36EAB0DD26D345" modified="2025-10-08" version="1">MALRLGGQTMYGYSQTGFDTSTTDAFMSSSQTLSVPSHFTYTTSPTSSDSSYLAGMLDNSSRASGGSPLLSLSSAGDTSPLTAFGGLPQTGTLFRSTSLSGSNFGDYLEVGDVATVAGSAQPSPSTSPSAHDFSGFNGLLWPSSADGSGTNDGIYGSYNGGSGSRGFDDISPLTDRSQYASPQESWFSGSLSNADDDSHNTSLSPHIAYQSEDLTLDIPGTHGLSADTFSFPAVSQSIASWSSMPTLDSTTTGGFQLPPAMKDSSKPARFSNAGLPQVVTTSYNDTDIGSSIIGIGGSSSSVRKAGKNDGSTGGHKRGSLGSRRSSNVGSRSTNRSSSPYDTTSATSPNRKTQPSPKHGRGSGSKGGSDGSSKNKFVCTRPDCNGPVFTRMADLERHIRHIHTDADKKERFLCDYNSCSRSATPFHRKDHYREHLREYHLEDLLKRGSNANHHTAASSSSAGASGPDSLSPSTAASSTADLKRNKKLLQETQLQNCKTENEWWRCARCLQRVDIAGRGWTCPGCKGSIEEPRKSIRMSRAAAAMAQTSTQSMGMPAGWGTYSDMSLEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR44</accession>
    <name>A0ABR3ZR44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-K/MCM22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020993">
        <property type="entry name" value="Centromere_CenpK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401:SF6">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="348" mass="37893" checksum="5D1867A432D4DB21" modified="2025-10-08" version="1">MEDAPRPITQDSLHAIYVERSIRELQRAVQEEEDVLAELRRGVAGAAPLTSATASLSIMATAYEAAARSDPFLPFADSVLPALLAMRKTHGVMAESETYLGGEGSKSSPALGEVQKWLAMDKARLEDQRSLQVALEERIVALQSGLEARGTMTAEEKRQEALDKLRTKKSDYDRDTAALLKSLKQFIQGRLGPMLAAEELGGPVVGGMVDVQTDDLASGFSSQGKLRKPPSGDKAGKNGKDRNEDRRQRRIDEIWGPRASAGEDGEDDEEEDRSNWDEATAAAVEMQELTEELLNAQAGAGGDSSAAYVTIARESAAARFLVRSKVAHFHPRDATKLRLIDFGRELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRC0</accession>
    <name>A0ABR3ZRC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-patch DNA repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="332"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="406"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="53112" checksum="11333B02EBAB2DDC" modified="2025-10-08" version="1">MAAPPPQPPRGTMSLYADLLGGGSTEAVPAPAAAAKPDAAKNPALRFQPIIRRPQQNAKGKAKPKTGGMPPSTRPLPQTTTTSVSAPLVKAATTTTTASTTQPPAPPRTSLADWTSGGADDGDDDYYEGNDGGGGYDDARKWTQRGGRKRKKKRMEDRQRMAERDAYVVDWDELYDPARPTNIEAYLHSDEHIDAVHAWKSVLYAHRREKQSARRRSSNSSSSGDERPQLNNAFAPPPLAAFAPPASYDLPAAATSTTPPPQRSSVAPPSQPAGLVVSKAPIRFAPAATEDHDMKDEDEDEDDYRPTLSGRADAEEEEEREDPELRTNRPGQAGFAARLMSKYGWTRGSGLGADESGIVNPLRHKKVGKSGAIGRIVGGGGGSGNNKSVQKAEESPENKISPVIVLRNMVTGLPDLDAEVADGQLVQDIGEECGAQYGRIERVYIDVPGELVFIQFTEAVSALRAANALDGRIFNGNAIVPSFYDADKFEEGIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRF0</accession>
    <name>A0ABR3ZRF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WKF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019327">
        <property type="entry name" value="WKF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306:SF2">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10180">
        <property type="entry name" value="WKF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WKF" evidence="2">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="466" mass="49157" checksum="ABBDA5515D6E2AFF" modified="2025-10-08" version="1">MPYPTTAPAQRVPAWKRLGLKLKGASDDNPASPASAAAPPTRPPAPTPGASSFSSANRQPYQSSPSSYSHNQNQSYTNTPNKRKEPPASALASSAVKRQKSVSFAEGKDGEAPKKAKKAKKPRKKKAEPNPANKEPSNLDRELEYLQQWKTSRGSWKFNKNYQTLLIKYVFAGGSNNEGIPASHIDIFYDYIRSLQGAVRTRLREEATNICKMDDEDKTAEAASSTTVTAAKAATPKKTKTETEVAAEAEYKKIVAGFRDQEGSGAVNGNGKRLRRLSEVDYVLRFADPVLQKRLLRRIRAENVANELSSDEDGEAASAAAAPKAAPATPKSTQSGSASDATSTAYLSSSSATTSGGDDKRVKLNDGSAKKPKRSRKQRTAVDPDSSDSDSSDSDSDSDSDSESGDEGAKVNAGADSSSDSSDSSDDSDDDMPSAPAANGAQTSSSSSSSSSPASASDSDSDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRQ6</accession>
    <name>A0ABR3ZRQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="123" mass="13626" checksum="34C0A6AE2DB9FA5A" modified="2025-10-08" version="1">MSTEREFQIEPLVQESILHNSRTLINVQSLTASLFGVGAGILGLESYNGFLFYIAFSLITTAFFFVFRVMSASLELRSAGKSVNTLDTSAFFRSPFDFWTGGLVNGLAGYILTWTLFFGLVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRT1</accession>
    <name>A0ABR3ZRT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000803</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="322"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="8">
        <location>
            <begin position="600"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="636"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="293"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="703" mass="75854" checksum="9855B935EC23928E" modified="2025-10-08" version="1">MEAASPALTTVRGFHGTPVTSGDEDSDYGVALRNNNRNTNNNGGNTPTGGKNSRRGRKKPIAVLNDVVSANCSPVLRPSGSGSPAMSGIAKLRMQLEPLSLDNSAASSRASSPGAKGRSSQLQPLAPVTTATVTVAPSVVTAARIASPLSPTKTRTLHKHQASQTSQTSQTSQTGRADFTIRNYDERPDSSSSTKATNSDGSGAQTGQSSRSTSHDGISSNTSGDETGPETNGETSGTSYVIQLEHDFISESVRDTHAFPVKETSNKATENSEMEASIFAGSLETDDLPPTFTSTSTALAPVPETTTATDDGKPKKMTADDFEPMRCLGKGSYGTVLLVKQNSTGRLYAQKQFKKASLVVHKKLVEQTKTERQILESVNRHPFVVKLFYAFQDREKLYLILEYGQGGELFTHLSSERMFSEATAAFYMAEMALALSHLHDTLGVVYRDLKPENCLLDAEGHLLLTDFGLSKVALPGPGGRSRAGSTATETSDDACCNSILGTVEYMAPEVVQGNKYGRAVDWWSFGALGFDLMTGNPPFRGRNNAKIQENIVKQKLVLPYFLSPDAKDLLTRLLRKEPRKRLGANMPKDLDILKKHRFFRKIDWVRLAAREVEPPIQPVITDPELAENFATEFTDLPLSPMMSPTTGPGGGRDPSPYETRPRGRSIAGGGPSAMSFRDDPFGGFSFVASSSLLNESNFPSFME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS52</accession>
    <name>A0ABR3ZS52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal membrane protein PEX13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PEX13</name>
        <name evidence="17" type="ORF">Sste5346_000108</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007223">
        <property type="entry name" value="Peroxin-13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04088">
        <property type="entry name" value="Peroxin-13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SH3" evidence="16">
        <location>
            <begin position="283"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="375"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1903481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="448" mass="46577" checksum="BDD86F378DE2DDB3" modified="2025-10-08" version="1">MASSDSPAAAATADSSAAPAIPPMPASLTSSVNQNAAAYSRLGTATTMGSPYGGGYGSSYSSPYRYGGYGGYGAGAMGGGMYGGGMYGGGYGGGMYGGGMYGGGMGVRDPNDPNSLTNRFNTNTQATFQMLEGIVGAFGGFAQMLESTYMATHSSFFAMVSVAEQFGNLRDTLGSILGIFTLMRWIRTLIAKVTGRPPPADAMALTPAAFARFEGRAAPPGADGVPGAPKPSRKPLFFFVLAAFGLPYLMSKMIKSLAASHEEEERRQMALQQQQQQALNDPSKLDFCRVLYDYTPDPALVAQQQQLNMQQQQQGGAVSGMPSLDLAVKRDDLVVVLGRTDPLGNPSDWWQCRTRDGRVGYLPSTYLRVMPNPAKEKAAAAQPQQQLLPAPPSAPSVAGSVATSNSGATTVAGGPASATGPDPVMAEKAAAQKAAGADTFMKSAFYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS99</accession>
    <name>A0ABR3ZS99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF14">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="375" mass="40843" checksum="AAFAFA2E568D6E1F" modified="2025-10-08" version="1">MSFGFRSLIDSAKKLAINGTHSTSAPITELFAKADPAVDGDDCSHDCSTCNIHYPRSFKIDHDDRLYGFVKGWSTHLIVATGKSDWVRDVADEKGSVMEAVNGASSPSNGRMMLSASNIPTPNHSSNYADPTRVVLLPAFVVVDNVTPALVPSVLEHLVNKSPTNTTPISTSPSLPPSLPTPLTYHQSPHSVLVLLCSQKTRDARCGQSAPLIRKELERHLRPLGLFRDLDDERPGGVGIYFISHVGGHKYSANMMIYRRPDAFGIDDLKRGSLTDAERDALPARIKSAIPAVLRGKKEETKEDAEKNGDEKEGEDGDAALNTSAAGASQCIWLARVMPEDCENLVKYTILQGKVVKPESQLRGGFDREKGLLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSA1</accession>
    <name>A0ABR3ZSA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="746"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1078" mass="117821" checksum="BE4C6D9236203ED4" modified="2025-10-08" version="1">MSIICLNVALSETPQTESGRRMALLYHLAPKLQDWFTHSGLPEDLKTFVSARREVIRISPMIPDLDQKLLCNYLIDLAVALALQYDERNQPQDLDEALKSAQKAKSVAETDFETLETLNVLPQIYARYFDKTGDKSDIDMAIKHTKDALDNIDKSKHLSSLRVELMGNLSNFLVKRFEFFCDPDNIKEAVECARAAVESQGDSPQGQHLESLARALSFLYDVTGDINNINEAVELVRRSTKLTNEHEDHDTAEALVSLAALLALRFHCDAEMADLEEAIQHAEAAAGLCPEGSSTWRAAEKVRLGCLISMIKWKGDGYSEAATAIGSVLNRTPKGDPLRVFGHIHLSEALQGRYEHTDDVSFLIKAVEAAETAVSETEGGPNHNAALHTLGSRLISRHETDPKETVDLKRAIETLEAAVTQKDHRHAGLSQYRRSLAVAYRTLRTPESNSQAYDLFTKVHGDSNAFPLARIGSAREAIAIAVKGEEWDDAAKLAADALELVPMACRRHMSRGDQQHAVKEIFGLAAEAASLSLRAGDAEKALQQLENGRVLILGYAMDNGADMSSLRKVDEKLASRFAGLMYKANADELEEYRTGESSLSQYTGQVGQLVKEWRASIAQQRSDERRNALQDIEACVADIRAVPGFETFWTAPKTAELQKQASAGPIVVVNMSRIRFDAILITTDTIKAFHLSGISLKQLPMEVSERLGASAAVRRWNAPARYRDGDFESDDDESDDEIHVPIDLYSWLWTAIVKPVLDELDAIGSLRLDGRSSAGRLPRVWWIGSGLASGLPFHAAGVDFADDATENTLARIVPSYVPTIKALASSREKESTLRVGRTAPGPGGGQDKKKSLLLVTMPTTPGQVELPGIEAERAAIVEACGDVCHVDEAQHHTAKAVLEKLAELSPSIVHFACHGHADPADPFQSCLLLYKPGDADADADDDNRRKPSVDRLTALAISQNAPEEGPAWVAFLSACDTARTKTLRLADEGLHLVSAFQLAGFAHSVGTLWRAEDATCARLSHGFYTELLRQPSTTEGVGDATAAHGGVAEALRLAVLSIRSDIRCRNPLLWAPFVHFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSP5</accession>
    <name>A0ABR3ZSP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000097</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07106">
        <property type="entry name" value="ALDH_AldA-AAD23400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="LUC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="36"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="506" mass="54027" checksum="881A58B37B9BA502" modified="2025-10-08" version="1">MPTATATTTEAGPTSVLLDFTTFFNIIDGQKMTTEATRHSTNPSTLEANPEVPVSTEADVDCAVQAARTAFGTWRNVHHAQRRAALEAYADALGANLEGFATMLTREQGRPLALTRMEVATTVERLKQTAALELKDEVVADDKASRGQTVLKRFTPIGVACGIVPWNFPVGLAALKLSSAVITGNTFIMKPSPFTPCANLKMVELAQQFFPPGVVQCLSGDDRLGPWLTEHPGIDKVSFTGSVATGKRVMESCSRTLKRVTLELGGNDAAIVFPDVDDVAKTAATLAQSCFFNTGQICISIKRVYVHADIYDAFRAAFVATASALPYGDGFNGADADGKTAPFMGPLTTELQYRHVQTLLADVRDTKLDVVGGDATLNSATDTAAAGKGFFVRPVVVDNPPDTARVVVEEAFGPIVPLLKWSDEADVLRRANDTRLGLGASVWSGDLRHAGEVARQLEAGNVWVNTHMMSHPSAPFGGHKWSGLGAEGGIEGLKQYCNVQALYLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSW8</accession>
    <name>A0ABR3ZSW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF4">
        <property type="entry name" value="DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045128503" description="DOMON domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="4">
        <location>
            <begin position="65"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="54885" checksum="1756ADE80E7B394B" modified="2025-10-08" version="1">MTSQTRSRPSTALAAVLSVGAQAVTTYCPSGATNVCYGIGIPESTASKGTGNIYFSISAPTSYQWVALGTGSMMSGSNMFVMYQDGKGNVTISPRAGTFHTPPSQDTSSNAAKLTLLAGSGVSGNTMTANVMCSNCESWGSSGKLSVTSTSAPWIGAWHAGSSLATTNKNAALTVHDNTAQYRLDMTKATISSDSNPFVSTSSTGSGSGSGTDSGSGSGSGSGSGSGSGSDTGSGSGSGSGSGSSGDDSDGGVAIVSLSAPNAAILTAHAVIMALVMVVLYPLGSALMPLLGKWLVHGIWQGLAYLLMWAGFALGVITAQQRGLLYVSQGKTHTILGTVVIAAMAFQPALGLLHHRHFVKHQGRGAVSHFHIWWGRILMILGIINGGLGLQLSMASKSVMIGYSVASAVLFLIYVAAKVIGSFMLAPARNKKNLDRGLVSANGQQGPAGGPDMAYRPSAEYQQPPAQQNGRRYKGPSAAVNDNGAYYANGNGANGNNGASVSPSLPPMRAQRPYQDDNDRRRNRMRREEQRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT47</accession>
    <name>A0ABR3ZT47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF158">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14490)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="64"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="576" mass="60979" checksum="332C14DC366B8437" modified="2025-10-08" version="1">MADTVPIKSVAVELSTNEPTVLETTPAGLSGPAVVPAPADQAVIDPMEVTNGEDERTGWRMYAILASLFLSLFIAALDQTIVATCIPTIAASLHSATGYVWIGGAYLLATAAAGPIWARGSDIWGRKPALLAAIVLFAVASTIAALSKDMTTMIAGRALQGVAGGGVFPLVTITISDLFSVRRRSLYLGALAIVWAVAGSSGPLLGGALTQLASWRWCFWINLPICGISFILVVLFLDVHNPRTPLKEGLLAVDWLGTITILAVTLLILLGLDFGGATFPWNSPKVIALIASGGAMIGVFVYTEARLATFPIMPLGMFSHWHNIAICIMSFGHNMVAIGCEFYLPLYFQSAKQASPLRSGLMLVPMTAAEAAVDILSGVLIHYTGRYREMMWVGTSLMALGTGLFLIFTPDTPIGTIIGIEIIGGVGTALLFQSPMLAVQNTVRQSETATATATMGFIRNVATALSVVLGGVVLQNGMNSEQHNLEAAGLNSTTLAAFAGNQAAANVDLVGDIVDPGQRRAVQDAFSDSMHNIFLMYTVIASISVLASLFVKQRKLQTEHSETKTGISNLERRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT99</accession>
    <name>A0ABR3ZT99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="297" mass="33672" checksum="93DF4AF8A8B7F2C2" modified="2025-10-08" version="1">MDLMICGMCGAQHDTRAIKSCKVCDDPRQYVPPEGQTWTTLREMQRSKKYQNLLVPDKYDSGVVSIYTTPQVAIGQRALLLCTEKGNLLWDCITYLDDDTVRAVNDLGGIAAIVISHPHYYSTALHWAAAFDCKVYLSAEDSDWIMRRGDAHVLWDGPRMDFLDGQFTAAKVGGHFPGSSVLLWKDRKKLFVADSITVIPSGVYHVNRPPNTASFTFMWSYPNMEAVLLKLTSKIPLPPEEVYQIWKSVEDLDFEDTHGAFITRDTRGESKQRMLDSAKLFIKFMGYIDHPIHKVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTF4</accession>
    <name>A0ABR3ZTF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">mRNA binding protein puf3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PUF3</name>
        <name evidence="6" type="ORF">Sste5346_000129</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="515"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="536"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="572"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="608"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="644"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="680"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="716"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="788"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="372"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="869"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="889"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="947" mass="101739" checksum="321242DADADA723B" modified="2025-10-08" version="1">MANQSNRFPYGGANSREPSSQPISTWQPNSVWGNVPSSVNNREPSKLRGQDEPFTNGHQTSNTFPTSSAAPGGVWTAQSGPWNNAESNAAIRRTSSSPSPARQRDTVGDLSNGLASNSSLYPIGQTSAYPNNRSKATNGTASETNAGTFRYSSPLRDSVGEDDNDSNTISNALSNLGFDSEALPSRTRAAHGSSNVFPASSAAASVAGSTSSTSAAPGPANGTAYNTNGSNGSGLPSFGSFGPIANSSHGHSHRTSLQASTSYSSPAAPAHALPYHRNSQPEDANTLAMAQMFRQSQALDERSGANSSMNGLGSNYNAMAAFAQAQAQAQAQASFQFNPISEPWDAGVRGFDMYGQVRDPAAASAFSSARGHFGSAERGNTPIGGVFQQGGSPRGFGTPANGAGPWSRPQSRDPRTSGLSEGSINGGASNQLQRQPLQNFLHDQQLSAAAAAAASFNGNPNFIPGNLASYPFLNSFRAPMQMSPLGIPMGSPMGNGLLPNPQLQAPRDRDLVRSMRSPVLDEFRTSRTNRRFELKDIYGYIVEFSGDQHGSRFIQSKLETANSDDKEHIFREISANALVLMRDVFGNYVVQKFFEHGSQVQKKYLAEQMRGKMVELSTQPYACRVVQKALEHILVDQQVYLVKELEVDVTRVVKDPSGNHVVQKVIEVVPREHIDFVMDAFRGKVKELSSHNYGCRVVQRMLEHGTADDKAVILAELHENARDLIMDQYGNYVTQHVIEFGDPEDRAKIIKLVLNEFVPMSRHKFASNVVEKCMQHGTLDDRIRARKELEKVGSDGVPVLHQMIKDQYGNYVIQKLLKLLEGEERRLFIENMEAQLAVLKRTSTGRHNAAVDRLFDELAKSGLISLGSPPATKSYAASTAPVSPRLNANAESTPPLTNAPNTPESSNPPSVSAGPTGASMVAKADGKMTATATKVAVSSDADTQTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTF8</accession>
    <name>A0ABR3ZTF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydantoinase/oxoprolinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048350">
        <property type="entry name" value="S-Me-THD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="S-Me-THD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="3">
        <location>
            <begin position="11"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="210"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="4">
        <location>
            <begin position="603"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="5">
        <location>
            <begin position="768"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1005" mass="106589" checksum="2A9B6597C70D3419" modified="2025-10-08" version="1">MAVDPSTKLIIGVDVGGTNTDAVLLNPAKSGAEAVIASYKATTGADVTTGIEEAIRVLLKDASVQPSQVASLMIGTTHLINAVVERDASRLSKVAVLRLTSQGYLQYTPPFIDFPTDLKNIMNGYQGTLSGGVQIDGTLIAPVNEEEVLKEAEAIKARGLRSVAVLGVYSPMDKKFAQEEHVRRVLQKALGDDVDIVCSKEIAGVGVLARENATILNASIMRFAKRTIRGFKRAMRGLNLTCPLYLTSSSGQLLSADEAARFPIQIFSSGPTNSIRGASFLSSNNSASESRFVVDIGGTTSDVGVLLPNGFPRLAGSVAEIGGVKVNFALPQVESIGLGGGSMIHVTDNNRITIGPESVGQALRQKALCFGGDTLTTTDIMVAAGKAKMSGTDVKVPEVAEATVAAARLKMKHMLEDHVDRMKTSPEACHILLVGGGAFLCPEELEGVATIEVPSFANVANAVGAAVAEIGAASEAVVDMVDREKALEDVKADVIEQAVARGAREGYVRVIEEEVAGLPYMEGKFKVAVKVAGPVDYERFLEGFAAGSDDSALGKDEDDEAYIEKKQWEVTDAVDSKPVIDVDHVNYRPNIGDDRVWNLSETDAYYLSIGCYILGCAGGGTPYGVYLQARQMLRDGGKIRIVDVDDLPDDMLAVPVAAMGSPVLAIERLGGNMVLDAVKDLQEHMNTTFAAVLTAEIGGANGLSPMMLSSSHALNNVTVDADLMGRAFPAFQMSSLYIGANGDINHLLPACISSGEGTTMTISKAKDSNAVDQLLRSAVMTMGFGAGIAARPAGKKELKEYGCLRSVSLAWRLGRAVCQARARGAITTVHEDLIREFGGPQTARKVFEGKITGIEQRLYGGRSQGTLVIEKLKDHEKENEEVGGASGSGTDDEEGPEKLWIPFVNENLVVEATYPSGEKKTLATVPDLIMVLDLLTGEAVGVPEYRYGLKVFVMVAAAHPLWTSTSNALAIAGPRAFGYDIDFKPCGTYTGVKSVIDEFGPARKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTH2</accession>
    <name>A0ABR3ZTH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein SOSEKI 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SOK1_1</name>
        <name evidence="3" type="ORF">Sste5346_000018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="567"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="816" mass="90594" checksum="3575147B91AE80D8" modified="2025-10-08" version="1">MSEQGAGGGVDSTLTSGHSRGQPSDETTSTEQTSEVRGQPAPQRSVNSNFAAAIIPSEQDPRSSEAGASTGTRSPPVTDSPSPSMAYEASQQQQPLQQVKAQDGRASHQPTLLQRAQETMAQNKQRRLQLKEQQQLRQQQQQLLEQQNKAQQLEQQQRQEEQQQHSSSSTQSPERRRHRHSSHHDQSLSHKQQASKIELPVTKATLSELDVNKIIHNPKLRHDINYDPELHFRPNLDGEKGRRKQDKAQQFWDNLRDELAQFVTDRDAFLKAHGPDDNDWTLPALLNAVKDIIQTLVPARDRDLLNEGLNVPLLMQQFARGVVDLEKLAAWLSSVLKLHCAPMRDDWVDEMYNELSRGNRDNDVAELVKGMCSLLSVLEAMKLDVANHQIRCLRPLLIEDTVHFEQRFFHKKIQNRRMSVSAARNWYEQAKSDFASPSVRHRQAFGNMAVFFSGLVHLLLPSVEASQVPNTFLFDEDRIVKLRSDMFDAIHLEVCMKVYEMAEMHEIAESQAAAAQATEASMSHASRHLAPNGVPSYLGTQSQAQSPNGDAWASYASSSLDEFDFNTPPQSATSGSPTSSRPTSLDFSACGSATSSPRNSGLPLGGDGAGAPPQLPEDFAEARQRSQNLYSSLVALLQSVPATARPSERWEDLWPLMAVEIYRTLSNVDRAQHVSLEQIEQRLKAAMSPDADIKKVVEHTFRERLLSALARRVKDYKTMPNVGLFVVAAGGRIHPTPARAPEGTSAAAAAATAAAAAATALMERNTRPIDPREDGCVEDMATRLAHLGILHWRVWGRLVYDPQPEMPADAPIPVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU11</accession>
    <name>A0ABR3ZU11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNAse1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047483466" description="DNAse1 protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="19718" checksum="E5C2B99256982FD1" modified="2025-10-08" version="1">MFSFRNIAAALALAATAQAQNTLTFVSTDNVDRTIYITPSEGVEGMDPVTVAAGATVAVNFATGFIGNAYAVQEGKENVPGMLAEVNFQGWGGSTYFDVSAIVNSADTDNVMLMYPAEAPSTPISGCNPFPCNNAYYLPDDVQTKVTEQTNIIVTLGGGNTNATAKRDVNTAANGKNMPRNLVELKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUE6</accession>
    <name>A0ABR3ZUE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C6 finger domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="29819" checksum="A69A173DF37A03C3" modified="2025-10-08" version="1">MALSPNNSMEVPAMTGSATTAGVSGVGSSSAALTTCLSLARICDATLAGSTRPTTEAAAAVLKREMNRIYTEIQQQAQTNVSVDHLASLAAFQAYLLYALVLFFQLGHQGDPFLRQAIMALQEIACTSSRHGLVCAAEQASACPRWAAWVVAEAKRRTLYVVYLFDSVLSAHDGLPTYLGSELRGLPAPGSKALWQATSLADWNRAYRLYLDEWTRTEDSAGGYAGLRIDELWPYPDPADVPGLSRRRQRVDQWLESVDEYGTMMYAVTSSTHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUH1</accession>
    <name>A0ABR3ZUH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clustered mitochondria protein homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Protein TIF31 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">CLU1</name>
        <name evidence="2" type="synonym">TIF31</name>
        <name evidence="6" type="ORF">Sste5346_000198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15466">
        <property type="entry name" value="CLU-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2280.10">
        <property type="entry name" value="Hypothetical protein (hspc210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03013">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033646">
        <property type="entry name" value="CLU-central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025697">
        <property type="entry name" value="CLU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028275">
        <property type="entry name" value="CLU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027523">
        <property type="entry name" value="CLU_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023231">
        <property type="entry name" value="GSKIP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601:SF6">
        <property type="entry name" value="CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13236">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15044">
        <property type="entry name" value="CLU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12807">
        <property type="entry name" value="eIF3_p135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103107">
        <property type="entry name" value="Hypothetical protein c14orf129, hspc210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51823">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Clu" evidence="5">
        <location>
            <begin position="320"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1027"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="624"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="907"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1244"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="629"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="907"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1244"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1296"/>
            <end position="1308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1308" mass="142943" checksum="0AC79F0B2E0536F4" modified="2025-10-08" version="1">MATSEDQGNAPTVAPVEENAVAENAAAEQVEVDEAEQAAEESLYNLTIVLPHSSEKLTIMIYAHEQVSEVRQAIIESPAAQQYSCFHLEYKGARINEFGQVSDIADLGLEAEIHVVEDPYTEKEARLHVIRIRDLIGAAGGHPDTVHGVLPGLSLFDSVTTEATAASEATPLEFDFTAPADQNTLLPRPSAEEVAPKTIKALQISPWNPPPAHLRQKGHLMYLIVTTNEGEQFQVTSHVAGFYVNKSSNSKFDPAPRPSPKAHSAHSLLSLIEELSPSFNASFTKLQEFNSRRDPLSTFQITNALPAAPWLVPAVSSASRTHSSDITRTQEAYLIAGTENVDNLRDWNEEIQSARELPRDTVQDRIFRERLVAKVFADYIDAATRGALLVACGEVGPLNPTEGRDAQIFVYNNIFFSFGADGVGTFTSEGGDEAARVATGKDVAGVRRINQLDLDGLYSPGTVVVDYLGKRIVGQSLVPGIFKQREPGENQIDYGAVDGKDVVAADERFVAPFSKMSQALNVKRHAVWDKDAKRHELEASVETKGLMGTDGRKYVLDLYRITPLDISWQEEGEAAEKEGAAAYPHRMTVLRPELIDIYSRVKMREWLDGELAKRNKAKEEAEAAAAATKKIEGETEAEAEKTEEKAEEKAEEKTEEGAEEGEAKAQDNRIDVSDFKFALNPDVFSGQVPQTEEEKEEMANDEKDVRAVSKYLQEVAIPSLISDLSESEISFPMDGRSLTQLLHKRGINIRYLGRVAKLSESEERLKCLHDVSLREMISRAFKHVSAKYLRYLPLPLSSACISHLLNCLLGASLNAKPTADIDRSIRSLYSDADLAFESVTPESLRADVEAETVRRFRFTLPDNWHIEMRNHLQLLREVSLKLGIQVLSSKFVFTAEQAAAATAAATTENGQNGATNGAHATNGGAANGEGSKNKKKKKAARDGSPSSIDSEARAAAARPAHTFSADDIVNVVPVVKDSAPRGSLAEEALEAGKISLSQGQKKIGQELLLESLSLHEQIYGILHPEVAHAYHTLSMLYYQMDEKDAAVELARKAIIVSERVVGVDSQETLLDYLNLALFLHQQGKSALALEYAKHALRLWRVMYGSDHPDVITTMNNAAVMLQSMKAYHESRRWFEESLRVSEQVFGRASLNSATLLFQLAQALALDHDSKAAVNRMRESYNVFLNKLGPEDKNTKEAESWLEQLTQNAVSLAKHAKDQEARRLRAGIKFTTRGAAAGSVVPGAGAGAKAGATPSNVAAGSPASVGGGKPSMDSRSIDELIKFIEGTEGTKKTSGGNKKRSNPKRRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGE9</accession>
    <name>A0ABR3YGE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000121">
        <property type="protein sequence ID" value="KAL1887410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="51"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="59194" checksum="340D66C67023B5C8" modified="2025-10-08" version="1">MASGKSEIQTIEMQEHQDQPAHNTGGPLMRSKEDDMGIWRTVLRHKRIGLIAMAAAFCASLDGYQINLNGNIVANKGFIRQMANPGTTIIAGKYVSAWGGIQSTGQAVGQILLQYATEGYGRKPALLIIWVVLTASIFTESFASRWDHWLVAKLLSGMGVGMLQSTMPLYLSEITPSQIRGFYINAYSFWFVIGQLFASVALNSLNKSDPYNFRTPIYTQWAMIGVIGIVFALLPETPWWLVSKDRMDKARKSLEICNGDVKDYDYDEQLEVMRATVAAERQEAEINNELGQWSVFQGRNLIRFLIAGWPKIAQQFVGLSVFNTYAAYFFQKAGSTNTFMVTIILSCVQLISMLVTAVTTDRFGRRPLTVYPYGVTVVSVLCLGIIGCFNYSTKQLSSLLIFFACLATFSTTGASAIGYAYATEIPQQRLRARTAAWSLAFSNMISIMFSFCTPLMINGTAAWGVKTGFFFAGTGTIATIIAWFILPEVTRRTPAEIDEMFNKHVPLRKFKGHVTEVQMRADQIHDKQDTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGZ8</accession>
    <name>A0ABR3YGZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010191</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="8">
        <location>
            <begin position="151"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="347" mass="37225" checksum="4E8EE60DF50C944D" modified="2025-10-08" version="1">MQHTLVLIVYSSASGDNVTLSPRLSPKHGEPVYDPSVKFTTLEGTGINNGTLSYYGVCHNCRSWSGGSVDITSTSQAAIFANGPSGSITNDAGDAPIKYHAEYGAFIMDMTAAAGSAAAPVLGKLSNNTTLSGSKLDGDVKTGKSDTVALIHAVLMIVTFFFLMPLGVLILRVGQSVRWHGINQGLSLLGAVGGSVMGFTTSSSYVRVCPPLHILTSSSNATNMPQSASFSTGHQIIGIAIFAFVLVQFGLGYYHHKIYKRTQQTTKFAPIHVWLGRVILPGAIVDAFLGFPLALDPKFDFILVALVVVLAPTFFVIMYTGSFYCHRQQPGFKLDENPVRSYNMDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHB0</accession>
    <name>A0ABR3YHB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_010066</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000112">
        <property type="protein sequence ID" value="KAL1887671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="10">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="37756" checksum="3560EEEB7D8699F5" modified="2025-10-08" version="1">MLDQRRKRIFWIAYMLERSVARTVGRPCAVADWEIDVELPANINDSLETDDEIRDALVAAEANPHQITSLTAAIHIIKMQQLESRMSRTVCRVDKPLSSIGDPKIAKLRQALEEWKANIPQVHGQDASPYTSTIYHMAQYHKALLLLFLPFLPSLTPAYPEFRLVIYSAGQICQLYKRHHENQSYISYSLLALHATFVAGLVMVYCFCQDPSVFDVQFSSDIRACSTLLYTISERWTAARKVRSAFESLVAATIETYDPAAPRNNNASNINSIDTTSQTAAGPVPPPSMGANLDTDVWDSFESVLEDYQINSETWMQDSIFLAMDAFPPDSFYVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJL1</accession>
    <name>A0ABR3YJL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitrilase</fullName>
            <ecNumber evidence="4">3.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009848</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a nitrile + 2 H2O = a carboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21724"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18379"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="EC" id="3.5.5.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.5.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF14">
        <property type="entry name" value="ARYLACETONITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00920">
        <property type="entry name" value="NITRIL_CHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="6">
        <location>
            <begin position="10"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00036406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="323" mass="36247" checksum="EC6DCAC7332FB00F" modified="2025-10-08" version="1">MSAAEKNTKVKIAAVQAEPAWNDLQAGVNKTIAIIKEAGENGANVVGFPEVFIPGYPWSIWGNSIADNAEFMNEYFRNSLEKESPEMDRIRAAVREAGVFIVLGYSERLRGTLYIAQSFIDPTGTIVHHRRKIKPTHVERGYWGDGQAESLKATVETPFGKVSGLNCWEHTQTLLRYYQYSQDTDIHVASWPLIWPQNSDEWVYHITGEASNRFSQVMAMEGGCFVMTCTQVLSEKGKVRCMLQDFDYAKANSGGFTMIYGPDGRELSKPIDPGLETIVYADVDLNDRIKAKQNLDIVGHYSRPDLLSLRVTTEPATVVHFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJQ8</accession>
    <name>A0ABR3YJQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc fyve domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000091">
        <property type="protein sequence ID" value="KAL1888481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="49337" checksum="D4B7DB20B1BDA3BC" modified="2025-10-08" version="1">MSKPDRSLLDRLNALKRSSVSLGDKTISAQASTADAPSVVPSAPPPTREDRLAARLKTLREARDGGDDNDGDESGAPEKEKPVTSPSPSGDTPTSERKTSNKDASSEEVSDDPLFYVDDEAVNDLLLELAAEGGLEDEELGDGEDEADRLAHGDDGDGDGDDLIPLPSVPKNLGDESSGDEGEDADNSKMVEDLLKSLAGTTVKDDVGTQGNSDKNKDGKKDGKKDDSDDSDGEDMEREVRRVLEQAQDEADLAKERSEGEVSEGEEDIVTKPRRRDTGKEDDILPGDKPSAEDDNFLGLPTVPTKLVDPPPSPPSLPSLSNDLPSVPTQTLPKRGDDDDISARLAALRGLQGKAAGLGQTDAFGLPSAPTFRPGEEEGGVLKRGHYGHGRRNYTDADQKAWCVVCLEDATVRCLGCADNNASDDEEDQNNAYCNRCWRDMHVGPAAGFDERGHKRVPLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK27</accession>
    <name>A0ABR3YK27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">beta-glucosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_009711</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000097">
        <property type="protein sequence ID" value="KAL1888237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF3">
        <property type="entry name" value="BETA-GLUCOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="410"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="856" mass="92470" checksum="D9BF73D755EE9040" modified="2025-10-08" version="1">MAAQYGPAGPSEDELKALLAQCTVEEKIQLLSLKNFWETSNIDRLDIPSLKVSDGPNGARGGEFFDGVTAACFPACVSLAATFDRSLCERIGAAIGQEAQTKGAYVLLGPTVCCHRSPVGGRNFEAFSEDPYVSGALASSYVKGLQSERVAATVKHFVANEQDTRRFTVNETISERALREIYLRPFEMVIKQADPWCIMTSYPKINGAHMDAQPTFLKDILREQWGYQGLLMSDWGATSNCDGSLTYGLDLETPGPPKHRTVEAVQSSLAASRVTEQDVDDRVLALLKLLKKVGKFTDRRATPEEQAVDRPEHRALIREAGAAGIVLLKNDSSVLPMNKTACKKIALVGPLVDIAAAHGGGSASLNCHYKVSPYEAFQKGLGTDVEVTTSKGANIYRAYPDLEAGSVNRNGNPGFIADFFKSNDLSGEPFYSEEYPRAAFTTLMNVSATGAQSVRFTSTYTAPVSGTHYLSFSGLGPSKFFINGELVSHQAEQMRDSMAFLLGVQDELRFQHTFVAGTAYEFVIESVPSPVSNSDLHLLDNQVAAHLGYVAQADMEKDLLAEAVGLAAEADFVVCFVGNTAQWETEGQDMSEMALPAQGSQDQLVSAVAKANPNTIVVVTTGIPVAMPWLSQVPAVLQAWYAGQETGNAIFDVLFGAVNPSGKLPVSWPKRYEDSPCFGNFGLDSYDSLQVEYVEGVNVGYRHFDQKYGNNDEVLFPFGFGLSYTSFSFADATIEGTFNKKATESDVVTVSVTVTNTGSTAGSETVQVYLALPTEGAGAGRPPKALVSFEKLYLQPGESKRTQLTFARDGAAYWIEGQAWRVDGGNHSVTVATSSSPRDVQATLELEIKEAFDFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKL1</accession>
    <name>A0ABR3YKL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="710"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="860"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1108"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1210"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1234"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1263"/>
            <end position="1294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1323" mass="150947" checksum="EF2491FCDF0E10BE" modified="2025-10-08" version="1">MSPDPANSSSLQSQSTPPALITTESQSDLAGEDANGSTEEIVEVVEASEDNSDGLPGPDACDDDDADKDGDKDGDADGDSVKSGDDGDNNSDYSRRRGGRRKRRSSTPEEPPRAPVIPKVRRTNYEGFKNYFNDEDSMYAIEVLDAGYNIKDEVARERLKRGAKTFRKPAIISNKSRQGTITDEIWIQRVRIQSTFILAHLRTVMSSAIKYDKTRTFFRPFHAFIHYQPKVKDVLEELKATVAERKANPKSPIEKPDDADKDKGSPVTFRRRRPKKGRRRSSANRDKRASSVSVTSSSGSDSNSDSGSESDDAADANMPDELLYSDEAIEHLQCYVDFVDKNIMHLSDLYKGTSKQRIRYSDLAYLFHPGDVVYSPTQSEFTGSTNAPPATNATAAVYQPIWKIQYTNPPSISDTCSEEYDKNHRFYISCFYIDYDGKNYGPVKYRFDVQPYEGEWDIKTLPVYPIRYHNSSNKGTSSQGPDRLRPAGKDFQTYVQARHLYYRGWTLTTSPNGDTLTDNNGDLMKHPEHIDSSVIVDFKAALQALPSWKPTFKEPSRMDEEWTTAFEDDMTVIQWSDSKRTRVVHRTAETTQMRDGAHAVETNDYADKDPFLVAYMAGNTDTRYELSEENLQLLPGRVMAYVLRDRKFVQLDVHYLSKIEQQSNVFENLKIAEHHKEMVMALVDSHFRKKEIKSPRHFSLGQDLIQGKGEGLVILLHGVPGVGKTATAEAVAQSKQQPLFVITCGDLGFTPKEVERSLEEIFRLAHLWDCILLLDEADIFLAERTRDDLKRNALVSVFLRVLEYYSGILFLTTNRVGTLDEAFKSRIHMSLYYPPLDRQQTLQIFEMNINRIEEIDRKRHEIRKREQSERRKEGGGSTSRASEYGDDDDDRVGRREETDELAHHLIVNRDKVMEFAEDHYDRNKQGRWNGRQIRNAFQIASSLAFYDKRQAWIQRSQQGKDNSKVPPDIGAAVLSDEQFQKVASATLRFERYMTDARGADDKHLAKIDRIRADEHVANEDPDFASQRERERERERDRERERDRERDMQLQVRRPADDDYRGTSSSRRFGGPMSPAPRTPQSTRRGGDDYDRRRDDRDRGYDTGSRYSGGDRDRDRDIRDRDRYDDRDRRGDHDYNGGGSVRGGAGLQDFRRRNGGDYEGGYSPRSTAGYDRDRPYDERDRDRDRGYDDRDRDRDDGYHYDRAPPSSARSRGGGGGGGGSDFDKRVNRNRTPTRSGRDHDGRDRPGSSYHDDTPTPADTVSTPRDTRDSRDVRDSRDAASPDHERERGRKSDYDPPSRYAGPGPSSYQSPPPSTGTPRGGSRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKZ4</accession>
    <name>A0ABR3YKZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Salicylate hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="111"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="47412" checksum="A19D722D6A092BD0" modified="2025-10-08" version="1">MPPSGIDVIVVGAGFAGLAAAIECDRKGHSVVLLEKVDDIDEIMRIGDIISFDPNGSKAFERWPGVIAAMEPIIRQTTWLDLYHYKGEFVTRQSFADEKSWGRRINGHRGQLHSIIYKHAQSRGIDIRLGQRVTDYFEDDNKAGVVANGQRLTADVVIAAEGVRSRGRKIVLGSEDNPKSSGYAVYRAWFPATDLAKNPQTKHLVQNGDTHQGFIGPDIHFLASSLKNGTEFNWVFTHIDDGNIEESWQFPGKVDEALAYLKDWSPLVHEIVKATPPGRLIDHKLVYRTPLPTFISPKARIALIGDAAHPFLPTSIQGASQSIEDGVVLATTLELSGKDKVPLGVRAFEKIRYDRVHRAQAMGPATRERWHRANWEEVWKRPELIHLAREPWLLHFDAEADAYEKYNKVTSNIKPAKETKAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM10</accession>
    <name>A0ABR3YM10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WD repeat protein mio zinc-ribbon like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008941</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16691">
        <property type="entry name" value="mRING-H2-C3H3C2_Mio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="5">
        <location>
            <begin position="587"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="4">
        <location>
            <begin position="1021"/>
            <end position="1099"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1108" mass="122718" checksum="30F09D9E99CB4DF2" modified="2025-10-08" version="1">MDGPETGLVRWSPNAAIDSFMHVNLNHRVVQLYKPTGYAKTGLFEFQSVSKHEDFPTLTSFDWSPTIPGVVAIGTPSGVVNLLKIDDDSNAYVELNLKMSRTCQAVSFSTSNLLAVGLDRVRSDRSLYIWDVNRLSSSARPVDAASLSSSATAAAGGFPKDMESFGEPIEVREASVSVSSMRFFEDNPNTLVVGIKGQGLRIHDLRDPGLHPLQFQTRCNNNLAIDYADPNYFASSALDHPGIMVWDKRATSRSMASPLYLDAVDVDELPWGGALRLDRAVTSESEQAINESKASVIRSLRYCRDHRGMLGVLSGSGQLKVYETKHEYCPPEMVADHSPELLEVRRSNEMDNQYSDPRHKNERIVSFDWVTIGSPALRPRVLVLRANGNYDILEKPSFTTTYPFKLIPWTAPYRGLEEGASYHSMMQLETNQATEVLYPVAFEEALADIPIFASDATEINGAIQQAQKDRAAQIDADALEQAKKSRLPPEYFSAKTVAKKLKILRQYEKQHLRQQAKKGAQAGTITGSTILSSSRTDLTDSTASLASLSGRPLTSQELHESLLTSTLARQGFPSEAQAVLDHVMLLRAKERYLFNCALNQEIVADDPWLRDVWGWVGDAEAAVNSGDMTAHFLDLSYMGVAGIWFEDLGANKDARIFGVEPATSPSFPDSSNWQRTISSICRKRGVRRYEGVETRKPHHRQLCLEICGWGRPPASSLVNNNNSGDANGNSNEKDTATERTTSYHTMAAAQALFRGDNRQAVQILKSASTEHPELLFVSLALQLMGRRDEEGIKNGAAGGGTILGAKGDHDQLDFDEAVASKTDPYLRAISSLIATGDWTTIAHQTSLPLRERVFVAVRMFDDDQLTVWLRDTLAEAVRTGDVEGLVLTGLTEPAVDIWARYVDKFHDVQTATLVMSMAAPRFVDDYRCTAWRTAYRAYLQRHRAFFQRAKFEVESTKRSKGADGRPKVAPPARQIALRCVYCDAQTRLAVPPGSSNSAQGAVTIPLDNHNQLPAKLAMAGVSCPNCKRHLPRCVVCLEIVGTPRSDRPEASADADTRLAARFPTFCLKCDHVLHLDHARQWFSRHSECPVPECRCRCNFKANPELNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM92</accession>
    <name>A0ABR3YM92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cell agglutination protein Mam3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MAM3</name>
        <name evidence="12" type="ORF">Sste5346_008894</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF97">
        <property type="entry name" value="METAL TRANSPORTER CNNM-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="80"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="341"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="528"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="593"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="763"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="689"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="785"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="795"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="825"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="837"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="850" mass="91011" checksum="435D30DD69EB7F0D" modified="2025-10-08" version="1">MASSLHHHQLGHNARPSPGHAFNGFGTARTLVLGLSRIIFASLPAVAVSAAPLSAFDAVSKRSGGFWPSEHLDSDDPNEGGANVWVLYIASAVLVLLGGAFAGLTIALMGQDSIYLQVLSRDDTDPQQKNAKRVDDLLKRGKHWVLVTLLLSNVIVNETLPVVLDRCLGGGVAAVVGIVFGEVLPQSICVRYGLQIGGIMAKPVLALMWLMAPIAWPTAKVLDHALGEDHGTVYKKSGLKTLVTLHRSLGEVSERLNQDEVTIISAVLDLKEKPVSSVMTPMEDVFTMSEDTILDEKMMDMILSAGYSRIPIHEPFNPTNFVGMLLVKILITYDPDDKIRVSEFPLATLPETRPETSCLDIVNFFQEGKSHMVLVSQYPGEDHGALGVVTLEDVIEELIGEEIIDESDVYIDVHKAIRRLQPAPRARPTRHRSLASDFGATASTAATRVADEEEIDDEGAEPSLQQQAIPVLRALSRSNTAARALSTSPKTTTVMMRRCSAGADGRLTKSTVPVRANIDEMWQHLRHLGPSNRANNPKNTRSTTVKIKQGHSHAGHQALLEPVVIADDLGSPRIDDETDDELEAGETTLLLAPKAYNGNDTQSSSHSPAPDYGTTRGVPQELDAETNGDEVLIDVVETPIVEIAAQSHESVASRDSGKQKFPASLGLGGRSISIDVNAGKTSIPGESAVRSSSENSPDQTSVLTTTVDISTPVSRRTIVRSGSITENVIETRGIRKVVLETTSSAEDDEDAVGVMTSSFVQQRSPLSGIHSPVAPRTPASGAEDETVKNKDLEAKLLAAQSAAASASTIPPSSSSQLDGTEVDNSETATAASGSGPSKKKNRRKKRKNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMW8</accession>
    <name>A0ABR3YMW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkaline phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045795656" description="Alkaline phosphatase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="52202" checksum="8B0C8FEAE0E7B300" modified="2025-10-08" version="1">MRLPSFFLAVAGLLPAVTAQSALNFTAFTHLNSSYTVGNGSFSVGVGKIDITPEPNPQWLPLNEYAFERIYVRAIVWESAGVYGAIINCEAATAADQVYTYGNKYVADLLNTSTSNVLFGFTHAHGAGPAGNVSALSYGGGGINGYENIGLAGLAAAKIALTNMKPAKVGYNNGTALFGVNSCHINQLTGRWTQATNTSGPVDHSVQVLSFVGRDDGIPIATYTSYAMHPVNSYLSGYTNGDWPGAMMRWIEQSFDDRDDFVAVMSLSASADVNPLARRTSANSLAAQQDIPINGLERTQEPVEEPLRDGYVRMKIPQVKYSRQLLDVLQAMGILLGEETIRLMSTTQEWHSNPTVYSRQALTTCPGRVRLDDAREGVPGVYTTGGTENLIRTGILAFDDIILACVGSGIYTDIGYAIKGNSTMPKTMVVAMINGQTASGYLVAANSWEQETFQALNAKIAPGPCGQQNVSLPLGAMIAHYKQTYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN41</accession>
    <name>A0ABR3YN41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.20">
        <property type="entry name" value="Gas2-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003108">
        <property type="entry name" value="GAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036534">
        <property type="entry name" value="GAR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02187">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143575">
        <property type="entry name" value="GAS2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51460">
        <property type="entry name" value="GAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAR" evidence="5">
        <location>
            <begin position="696"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="393"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="521"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="659"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="800"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="946"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="685"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="801"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="837"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="873"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="965" mass="104892" checksum="0B06F031893AEDD9" modified="2025-10-08" version="1">MSGFPILTAPTPRLSVPSRQYYRSASGSPTRQHFQQHVDDLISQLTPATAVSALRFPTGPLKACLDTATATEQSFAMRAALAASSIQEWLDELIEWQWPEGGGSGGFEEPVHRRGKLFASTSPTSSRPVPRTFSPPSPITPERQVLRTSSRTSDAGGERSWMGSLRAEDVALYGERIIEIGHEIDDLEVEDMKQHVLHHHILPFSPPGTPSLGGRPRSSSVSTANFTKMDDLSAVVTAIVLQALPLLSKLVRLLDVWRIRLLVLKKIPSYLASLAAAEVAIQSAWNAVYPGSKDGSPSQLMNLSNGPTLRREEFAIMKSVVEGKVSKAARTTDFLLDTLDGWEDTIPEQWIDRIDAAERDYGEWVVLCERKIRESDWKKVTVNRPSLSPPLPIHDAASVAPPAVPGSPTAKGKREAPEKLYNMAPLDSRPTTPDIDVPKTRNMFPILPRTPPRALSAASSLESLRSEPELPSFHIANHDDDDTELDSPSASVIHVSDALLPSDTDLASDDLVARSYSDDVVDDIPDLGETSGITETEDLEDCQAADASPSSSPPDFRASIRSTVTFNDMPTVAEIPGEESPTGPEMPVDSSFMFDDMVNDDSELPLPQEMPSYMDSPGSPASPASINSRRMSVGSEDDQLQQQISEILESIPAKIHLASQPSPSFSHLNPPDFKLPRKPKAPTDSTRSLSSMSSRSMTPSFLLAPAYSRNPRPRQQKGNQEIKLYHLSRSTGEAPIKLFIRLVGENGERVMVRVGGGWADLTEYLKEYASHHSRRSKSGGESKIEIRDLPLSSSVAASLNSRFGSSPPSRPGSALDSPAAAMTPLNIRKTRRPTSAMGDTSIGSINNDSSVLGKNPRTPLASMTKPSTDTPPSDNSTRSRSSSRLSWTEEDSSLGMSGPRAKNIEMSEESKAWVESVKERVRIASGERRVSDQLEGKFGEIGKVGGTKRLFRKGPSTGKGIGEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNA5</accession>
    <name>A0ABR3YNA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RLR1</name>
        <name evidence="9" type="ORF">Sste5346_008971</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
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        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="8">
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            <begin position="148"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="7">
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            <begin position="948"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="6">
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            <begin position="1317"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="649"/>
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    </feature>
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            <begin position="1555"/>
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            <begin position="46"/>
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    </feature>
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        <location>
            <begin position="67"/>
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    </feature>
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            <begin position="100"/>
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            <begin position="127"/>
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            <begin position="652"/>
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            <begin position="1749"/>
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            <begin position="1766"/>
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            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2741" mass="295926" checksum="AAE971EC5E46B40B" modified="2025-10-08" version="1">MPPKRKRGGAADSGGVRPSPHRPEQTNLGQHDRGYNNDGVGNDGSTRGGRGSGGGRGGGIVGSGRMGGDRADRARRGERFGSQGPSHDGSPVPPSNTNGAASATPSVTASPVTVARPLPRNSTPATPAEPPAPLAPPRPSFPQVYTILTDDRISTWTTGTGRQEIIKLGEKARTDEDEVELSTLFQEILRSVVDRRLAPAEPGAVVKQILGDDSAQTPAATAAAAFSPSIIFLDTVSVFVEVDDSASQPASIPLLRAFMSATAVPPALMRQILDHEFLMRLGLLRDTFHRMTIRFSTNLLYRQQSYNLLREETEGFSKLVTELYNNAVAQQDPSFDSARATFEKVKGLIGTFDLDVGRVLDTTLDVFAATIIKQFKFFVKFLRISSWWPRDHPGHPRSSFFGGLPRWAQPELAAHLAAINSAAAADDDDSEESALVAEERRKRDIAFWDIARKVHLHAFYQLGGREIADPRLQKLIEGATSNGKAEDSLDDMLLGDDDDDIKVDDNTKMDLTTANDNTETTDISNFSENELQWIKTTKTMPPPGNRVAAQILGFKLRFYSSNARNADDILPANLLYLAALLIKIGFISFCDLYPHLWPADDDMDGVRKRREDELAKKEESERFGSADAALLATVLEDDDPPAAPALELSKQAAPTSTDAAAAGGAAATETPADAAPALPAPTDMKIQILDQLLLIGAIPEALFILGRYPWIMELYGENLLPLIHRILLQSLHKVAAEARPAPASGAESSSADAPAKKIAEYDQSGTLKGYVKRGEQGIRRPFRWPFADKLDVADGQPYRYYFDEWLDNVPVCQTVDDVFALCDSFLGVSGPSIGQEPELVISLASIGAKDLHENPSPENRQRWYDLLQRLLVPALSLVPANPAAVDAVWQLLRTYPLKQRYELYAEWFEGSVSRQPVMQKAFARTKREALRIMRRISRENSSLMGRSLAKAALTSPAIVFKVALGELEAYDNLIDVFVTCARYFTDLGYDVLVWSLMGSIGGRRRSRHNASSVLVASKWLQALSRFAGLVFAAYPNMDVKPVVQYVTRRLSAAGDPGDLIILRDLIVNMGGLVADSDWTEAKIQGMTGGPALRRLTLLAMGDVRDDADSSAKGAAQRRSAQRLVKTLVDAGLVGRLLINIAQHRQAAIYAPAAKQAHIKYLATLVDDSQEILTQYLDLLRNTLSPAQFDALIPTIPELMKEFGLDANLAFLIGRPGLDFHAAMAALPTPTMPSTTDDTTVAKTDVPVTEDVAMKNGDDSQKTETDEMTIVAKAETNGAEMEVDAPAETETATPAPSMGALQPLVDFISETLPERVLKRISPEFFVTFWTLQQGDIVVPRARYDTEIDRLRKESSALKNSRAVQGTENPRVAMMRRNEEAETRLKERQIIAEEMLALGTRNRDTKRHLLVQAQTWFTNNGSSTVTQASASALADILLEQCLMPRILLSVADAEYAFRFVRFLHENRVPHFQLATFYQRLFSTNRLRDLIFTSTVREAERVGRFLKLILADLARWHSDKNAYEREGLGQTKNGRRNYLGFIKNTKAAKPVVALVAEGDDEDKDSKDKDAKDKDTTAAPSGPTYIEHTEFRDLLYSWHKNLNMALKDCLENLEWTHIRNAISVLKAVMDAFPAVDFMGRQFADQLKRIAAREAASNNTTPEASQRVDLSVTALAIYSELLRRKSKWVMVQAFRSNVSSKSVSGDDKSKDSSSNGETGLRPDAPEFRPQRLGGADAEDGELRDAGVNGGNKRASSTAPSTSSATGGGLNSKPSTPRSGAAHLSNSSRGGDAHSQLPKQPSALTSLPHSHSLPNRPDFSVGGGRFAQGDRFGQVRNQDRRDAGSPRGSSDSNSNNNNSAGNASNAQQQSQAQKGAAPPTDPRGPRDPRDHGRDPRDLRGGAQDNNSSNSSGGRPDRPPGGRDFAGNMPGERGGGGGRNSRMDNTPTRRGDHARDGRDGRDSRDSRDPRDTRDGGRGPRDSREPRDGPATGNNAPPTGPASLIPQKRPDVAVQEVAINPERARLLQDDGKDIRSSRTSGGSAGGPSTPGGGGGRTQSPRVSDRRSQPSVNETTPANDRGGRGGRDGDRDGRDSRDSRDNRDGRDGRDSRDNRDRDRDRERDDRHGRLAPAAAPSQPAADSSSRDGRPERSERSDRGERSSRGGDRGERNDRTERSDRGDRGERGERGERGERGDRGERGERGERSERGDRDRDRDRSDRGERTERSERSERGDRNRPAPPQDLSYGRLNAIPSVVDTNSTPLGPRGSRGRDGRDPRDQPQDGSRDGPRDGGRSSQQQQQQQTSQNSTADSQNQPPSGPSRSSRRGRGGQLDGASGGGGGGGGGGGRNSQGGSGLPPTPSGPSTSVNATPVSGDRVRQFNNPSNSRGTPPPLPPPPPPGGPSSAAPTHSGTPDRSGQQQQQQQRGGGGGHNLPHTPAPNNNSGGRDIRGGHDGGSNAATPSSSSRDQNNNSNNALRSRGGSDRERFLKGIQDTISGGPSSGSRRSSNRGHIAGSDAQVLTGGLPTPSPIFERNDPLRNAGGDNNNNNSGRSSRQSNGGGGGGGNDRRDRGDRGDRGDRRSSRRGSRERSPGGGRGGQQNQQNQQQQQQHRGLPPPPPPPPPGPPPGLPPMPQQQQQHQNSNNSFGGSNRRSSNRGGDSFGGGGGNNGPLRSGGGDPNREPMGPGRDSRRSGGGGGNDFRGGGGGNDGGNNGGNGGGGRGGRDDHRGRKRRSDEGVGMLSNDREKKQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNE4</accession>
    <name>A0ABR3YNE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonineeeee-protein kinase ppk6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42084:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PPK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42084">
        <property type="entry name" value="YALI0E26631P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="560"/>
        </location>
    </feature>
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        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
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            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
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            <begin position="241"/>
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    </feature>
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            <begin position="541"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889380.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="782" mass="82860" checksum="6926BB8164B3F18B" modified="2025-10-08" version="1">MSADLFAQFGPFSGSNSSGNQQQGQGQGQAHAQAQPSRAAQQSDDPFAFLSTAFSQPSASPVAQQHSPFSTSQSNTPQPQQWSFGTPSQPAQPAQSQFPASQSSPPQPQQWSFGAPPQPSQPAQPAQPSLNWGSSGGGGWGATAAPAAALAEDDEDDDTWGDFEEASTGVQAQPPPVAAPPAYQANQASQPAAPPSQPQEPSRTRIVRASTMDLISNTLVNFGDAPASVNALVSVAEPAHSPNPPQRDPWRNPVPEPAPAAKPKPKKPADPNVLFDADDFDVNETFGSDDDDDEDDDEFGDFETGHTSPPRPAVASTNHFSSFQPASSRPAAAKPAPTPAAATALVDLLSLDDSEPSPITASYPMSQPQETSGIGRPAANLLSPLSFGSTSMTAQSNSQAPKSPSFQERNPFPGLAVTTPISTEFPTEKVKNRTPSPVTTWPSFDESATSIITSKTKVPPPSDDADWDAWGMEDSAPPKLAPTQTKRAPSPVKAKSKPKTQPKKAAPVAKPAPETSDWDWDAEEPSQGPDTTASSTPLPPAIANASAPNSISDKAPPPTNVPPPAVLLSLFPTLMALPEQALFKPTATQPVEVRNRVIGNPKTIAFLRNYLQIIVVAGRVVAGRKQRWHRDKFLSQSMSISAAGSSKGGGMKLAGLDKAQGQREDREAADVVAAWLRHVGKLRSTVATANAALLAAEATEHKHYPPLRIPELQSATIPITVAKNVPTSTKACVICGLKRDERVRGIDGDDVDDIFSEWWVEHWGHRVCKNFWAEHEAALRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNI8</accession>
    <name>A0ABR3YNI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ski complex subunit Rec14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rec14_2</name>
        <name evidence="5" type="ORF">Sste5346_009232</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="214"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="354" mass="37488" checksum="7640ED730525432A" modified="2025-10-08" version="1">MSKQYYIAKAVDNAHETDIFSITVTPTSVISGSGASTLRVHSMTTAEYPIAQSIDGAHKLGCHHVTTAKGSPGQVACSAGFGGEVNVWRRIEAGDWALDTTLRPSDLVKGGTTAPAEGEDGAAEAKTEKTTDAWALALSKNEQYLAYTTHDGRVGVWDLQAKAQLLVYSAHNRATSSFAMAVDLSQDGKYTAAGYQSGSVNVFNNDQSKLVYTLPGLAKPVRAVAFSPLGKRLAAGGDSGVISLYDMKHGEPVGNLTPPGSTTSSSAVWVMSLDFSASGEYLLAGYMDGKVRVWNVELGTCVATNGETEMSAIWSVKWLPPKSERPGADTESFCTAGADRRLTFYREAGSNPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNV1</accession>
    <name>A0ABR3YNV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Yippee domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008469</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="195"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="238"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="395"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="457" mass="49529" checksum="9482D7307843F792" modified="2025-10-08" version="1">MFGRTRVYESRPRPYATFLLPSFPSLNWSRKVSAATSDHPESSQQETIAVQSTLPPNTYHEYVETDSHRFSVASAASSGSTATVTSTGSQATAPSLSTSLSTSPSSDIVTTPQSLFGSPITAPFPIFDSIDYQQPTFAEFENGSETVETGVTSPSTYKSGPQVGTSPKRHQPASPLATTPTAAGSSRRLERLFPTTLRCRRCSADLAFASQIVSKGFTGRHGRAYLVSAPSTSPDHLFAPEVKEVKDEDIPWEDSDDDDEDDDYSRQKFRPGGARDLPNITIGKAENRRLVTGAHVVADISCAVCTTKLGWKYVDASDPAQRYKVGKFILEIARLATHHVWEDVPTGAHAREAGVDESEGGSSSAGEVDGPSPVSDPMGAVRQLMARYQRLRAGNKEINFDEEEGDDDGSHSPADPIEFDSEDDDECEDIFMGTWDADVVARRRAAKRAESLASSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQH0</accession>
    <name>A0ABR3YQH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008419</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF13">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32643" checksum="AB99A0037360A87C" modified="2025-10-08" version="1">MPSDYRPIRHSDDDAEAQDAGESTRFIRSSDSNTSLSEKPSSTGSARWKRACIVIAVLAVTNVSSLIMGALAGRFSAYGPRHLDTQCAAHTTQYSPLLDDVNIHYAPVKFNGSFLEETVYRRPGAPDVDAAWEALGVDYRAGVIPAETGPRSGLSENHVQRADQYGGGYLVNVEGMHHLHCLNLVRKALYYNVDYYKAMGTHAFLNDDNILQKHVSHCVDILRQVLMCNVDTGVLGQVWYDQDHPAAFPDFHTTHMCKNYDAVRAWAEQLQAPPNDELPADYLKTANPGAVLPATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQT0</accession>
    <name>A0ABR3YQT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lysine 2,3-aminomutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00238">
        <property type="entry name" value="KamA family radical SAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538:SF0">
        <property type="entry name" value="L-LYSINE 2,3-AMINOMUTASE AQ_1632-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="LYSINE 2,3-AMINOMUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57585" checksum="0D89B752ABAC5D8E" modified="2025-10-08" version="1">MRYAFSQRRIFLHGGMPGLMERLSITTTRGVATMPPRMAPVAAAVEQAQQQEVTVVQDTSVVQDAAQAPPPRPLFIDTIPPQDEFWRKIPVWKDVPMQTFLSYAWGIKNTVQGEGKLAHFLEQVLPDEVPMTDVAHGISCKQTQTREELVTDVLDGIKAATMSTRMTPYILSRINWSDPRNDPIFRQFIPVKSRMMPDHPKLTLDSLHEHADSPVSGLVHRYTDKALFLPTSVCPTYCMFCTRSYAVGGDTDSVKKASMKPTKRRWEDVLAYIESTPQLQDIVVSGGDAYYLQPDQLVYIGKRLLAMPNIKRFRFASKGLAVAPARILDDRDAWFEALMLVATQARKAGKAMALHTHFNHPNEISWVSKMAARRLFEAGVMVRNQTVLMRGVNDDKETMLSLIRNLADNNIFPYYVYQCDMVEKVEHLRTPLQTILDLEAQIRGSIAGFMMPQFVVDLPGGGGKRLACSHLSYDRTTGVSRFVAPAVTGRDKENKVYEYYDPVDSVVKAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQU1</accession>
    <name>A0ABR3YQU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UNC93-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008732</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06178">
        <property type="entry name" value="MFS_unc93-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="56132" checksum="3D47B2A77A8584DB" modified="2025-10-08" version="1">MADEKNISAVPETEAVAPAPVHAPEEVAVLGPDGQVVRPPGWKYKGFRVFGKELWYASPEVQLVMVAFVCFLCPGMFNALTGMGAGGQVDSKAQDAASTALYSVFAVVGFLSGSFANTFGVKLTLSLGGIGYCIYSASFLCYSHTENDGFVIFAGAFLGLCAGLLWTGQGTIMMAYPPEDKKGRYISWFWVIFNLGGVVGALIPLGQNIHTTAAQTVSDGTYAGFIVLMFLGAVVAVLLVNATSVVREDGSKIILMKNPSIKTELIGLKDTLFDDPWILLLFPMFFASNTFTTYQTNDMNAAFFNTRTRALNNLLYWLAQMLGATVFGYALDYQGIRRSMRARIALLALGALTFAIWGGGYAWMKMQLPRELATPTNPNYVPVDWTDGGKLYIGPMFLYMAYGFYDACWQTCIYWFMGSLSNSGRKAANLAGFYKGIQSAGAAVFWRLDGVKKPFRTIFGATWGLLAGALIVAAPLIVLRIKDTVTIEEDLKFSDETIEDVIAPGALHEKAVHHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS93</accession>
    <name>A0ABR3YS93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF32">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="25166" checksum="1C87BEDD1C7F3977" modified="2025-10-08" version="1">MSTKTIVFITGTNGGIGYETVLVCAKTSPDFHILLGARDVAKGQKALKAIHVELAMTGRPVSSIEVVQIDITDIKSIEAAKNYIEQAHGKLDELINNLTEALEPLLKKSSKPYLIYISSGQGSITQRLDPNGPYVQLRGEPYRMSKAAIKMLSACHRFSFAEWGCKVLAFDPGFCVTNLSGEEGRKRRVKMGARTPEEPANTLVDIVLGKWDEAFTKSGLLDVDGNIVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSJ9</accession>
    <name>A0ABR3YSJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.282</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007976</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TYW3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.282" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA wybutosine-synthesizing protein" evidence="10">
        <location>
            <begin position="12"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="379" mass="40200" checksum="19FE3B0B98568F32" modified="2025-10-08" version="1">MLPPCPARFTTRKAAILELLARPDDDYTDASPKGAVDEGIRPLIDVINKLDGFVTTSSCAGRVAVFLEGRKGAAPPADERSVPASTTPVPVPASTIASAGGKGGGGKWLFVSHDPLVNGVASDSTSPPQHSSYSGTDWAPVFGLEKDEAATNIDEETVQDNVEQDEERLVHFKFEPMILHVLTASLEHAQLLLRCASAAGFRESGAVSIVPPPLPPAGRGAAATGEDEDDNPSMPIVAVRSMGLALASVVGICRADKAAKENTDSDSAHCIVTPNHLARLARVADERFAVNRTRTERFRVALVEAIEKEEREELAARTGTVVPKRRDENWEDAEARRARKKEEGLRRQAALKEKKAGAGPAQADGADLIAEGLEGASLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSK8</accession>
    <name>A0ABR3YSK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="566" mass="62951" checksum="612997FF1B5A3B11" modified="2025-10-08" version="1">MDIFRNARQNFLRRQAEAEQADLERQQAREQELQTQEQSQQPEMQQRDTAQPQTARPSPMSGILRRFADIPRPSMPSMPSFGRSQPRPTSSHYTTASNIGTTTAGAEDDEIVSPKTPQFGTLGMPPMPSTRLHLPNLQRTWTRGSSGPPSRPGTATNAVPMANIAEPVPAVPAQHVTSRHRSGSSLSEASFEGEDDRRQRGRRRRFEGADPAEMHLASMADDGRRRRRERRQASDGFNNTNTGNSSSGRSSRRHRYQRQYVVDMGVSPPYPGRGPSDPNAKPKKFLFCFPYIKSRRLRAQILRCCVSGTFTALMLGVFLALYMTNNIYNTEFAVLLILIMLFTAVFFVHGLIRVCVMALHPLSPAEEEAAEEMYRRRRRGGPAGLPDMYGPGGYAIPHQPIRVVLARDEEAAGLESVTTKIQPPAYGLWRESVRVDPNRIYWQRNEETSATGSTTETTRSRDASSSNSSNSSNSSRSSRRSRSATMRGGEASSYADSSSSSSRPSHDRSNDDSDRGRQSPRPPSYMSEDGVQYVVEAQPRSIAPTTEIPLPQHPSEAGRTAPRPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSY0</accession>
    <name>A0ABR3YSY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="664" mass="74732" checksum="695A153E1BB8C1CF" modified="2025-10-08" version="1">MSNNEDVSDYEQYFSTDSDGTLVGTSRAMTPPEQVMAHERSDPADLLIHHGDAATFIKYSHLNIWDNIMPRLDRAGIAFFTISFRGAQDRFFPLVAGQGGLHPMTTPSNQLDFLTKLARDLPDHYVCEQCLKLHKVDNETEGFAADIAFVENASHEKKPAPVCPAALEMPCQRKKAILFPAFGSSQSLEHTFTGGLSSVRRTPLAGLLHRDVELTLKRARLLKYIEDKEQEELAAELNEVVLEESRSEREVVGRTVTRPIVLDDGDATSEDEGETVTTVQEVANEESATEEATAEAASETEEMTTVHASTNEAAAELAEAGPSTAWARPSKAPNGKLSNGGEGTRRPFRKNGWMAIVADTVASTANAFIPERWRPQVPPTLRRMQRAARQARRYARQVREIREQELRERRKHLETTLHASLRPITADVSLEKIDRISRSRYPFRETTTAKYTFAPRIQQGHYLLKTTIKLHRQEARNVALSICPHQLLNYHPHSASTNGPNNIAAFRFQSAVYKVDDTMKKKALSLRERYELGACGVDEFDENEYESDNDVPERCKDNKGGMRQRGSCHRCATDFCVRGLSRKIQIIIVVWQDFGEETCMTDINWQSHIPGDMLEREDGLNPAQRANLWDQGPEMHHLTGGVRALYEDKPLWLEDFGDIYSAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT17</accession>
    <name>A0ABR3YT17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-specific protease doa4</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DOA4</name>
        <name evidence="4" type="ORF">Sste5346_007610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="471"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="810"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1204" mass="132827" checksum="E93515B610BBF308" modified="2025-10-08" version="1">MTNDYRPGPAAANGAGVGANGPTTSTGKIHNYVHFDDIKHATLGVDSVTPVETVLGYAESCIKQADFMKDFGRLDMALKEYILASIALLEVLPSNSAWMSVMTDQKGARTRYNALMARISASSAAYEEIKAQVKEDNARSGVQPMIKAPQTQPNGQSNNQSNGHGHGRNGHRATGSLGLLNGDGPAPPRPSGPPPAPPTTTTTTTTKVKPAIHPKPQALHGNAITPAAANGRGSKTAQELAERFANLRTASSPPTKEPVQDPRIRTQPINHPSFQHLQKLQTQQSSSPSPSPSQSQSSLQSLPQSQSLPQLQTQSQNQNQQNIYSQFQNFQLNMKGFESMPAPINRSNNPTMMHALPDLPKLPDAIYSPARGSVSSQATQMPVSTPRGSTATPRNGMYSRTNSLSSFSATNTGKSATSVTEDYFSSPYNHSRQSSRPSQDSARSKKPRVTIPDGDTIEAEELYKLIQAGSKDIQLLLVDIRSREEFDEGHIMSQATICVESDVLQREDISASQIADSMVLAPVSEKRQFDRRADADLVVFYDTDSETIIRNGKAVSEAGRAISSFHDALAFYDYQPDSDTNVHPKLLRGGIEAWISLLGPNSLQTSSTSAETAGVASRAAALRAARAAQRQRASTFTRPQSKYMAKPIQDANEAKRWEESLKDMDKSAGLVRTTDDFLRRFPPVSAIQESMTTPAATQDDSEIGFHTPTATDASFKIKPLHDRPSSRAAVGTTYSEHKGAPIQSSPAAAAAAAASLYSTLPAPPTRPPPTVPRQTHNDVAEADDEDHYMRTKLAKAGVTGGVGRIRRQKVGLYNPDNWCYGNSSFQSMFASGSFAEELTTGEWLSHWKVPMKTDEKISHPQLLAKILANSFHWMQYGKFEAMKAKTLMDYCYHIHSRDFDGSIKTDRSMIFGGPYQQDAQEFISFLLENLHDETNRLRDHTGEVQQPPLGPRSTALGNALLYWKEYRKYNDSLVDKYWRGVEVTDRRCRACGHPSLTYEHFDAIHLPIPPNEASTATTMADLLGQYCSADLLDEYKCDQCRRIDTTEKRVRLVRLPDLLCVSFRRFQGNEHYGFRKNNTAVVFPINGLDMTPYTMQGITTPEDQAADGIFIDDPTRTEQQFRAPFIYDCYAVIVHSGTLKSGHYRSFIKDEGAADTNQWHHFDDARIEPVIIGSNDSRDMARRLYRDNQHGGASAYMVFYKRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTW4</accession>
    <name>A0ABR3YTW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secretory lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045015249" description="Secretory lipase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="48582" checksum="CC44E2F712157F46" modified="2025-10-08" version="1">MKFQALVLSALAAVAWAVPAPAAPAIKHKRNSPPLPSEDPFYSIPDNIHSYAPGAIIDHRAPPAAIAAFGTDKINIAGSWQIRYRTTDNVGNATQTVLTVLIPNNADFNKVLSYQVAEDAASINCGPSYALQLQAATGGLLGTIVTEAELLLIEAALYQGWVVILPDHEGPSGAYLANRLAGQATLDGIRAALASTSFTGIQGDAKVTMWGYSGGSLASAWAAVLQPRYAPDLSDNIVGAAIGGTVPNINNVINTINDTPFAGIIPAGMMGLASQYPVVAQAIDEHVLPEDKDKFEKVTQQCFVPDILDFLLDSNVKAMVDNQSLWTQPDIQKILQDNSLAYESAPPSSIPLYVYKSVFDEISPIADTDNLVKAYCSAGSRVTYTRDLASEHASLAAIGAPMAIAWLIDRMDGKAAASSCSTTTKLSSLFDIATIEVLPSFLFDALEALLGGNIGPTFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU23</accession>
    <name>A0ABR3YU23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007424</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031632">
        <property type="entry name" value="SVIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15811">
        <property type="entry name" value="SVIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="134" mass="13531" checksum="9C35D4FD95970307" modified="2025-10-08" version="1">MGNLCGKVDKHDDAFDRPGRTLGGAGTGSGNARPVGGGNVQRAATAPLPPRVGGPARTLGGNSGGPGSSAAADARERAAAAAEARNAPKPTTGKLGAQLEAQKRENRNETLKKASEAEVRRREMDAQAAAAQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUM3</accession>
    <name>A0ABR3YUM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enolase</fullName>
            <ecNumber evidence="4">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_007857</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF6">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="11">
        <location>
            <begin position="156"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="457" mass="49006" checksum="0F00C339B8B8F20E" modified="2025-10-08" version="1">MTTIKKITAQQRLDSRGNPTVQVQVETKDGFFRALVPSGASTGAHEAVELRDGKARDAATKGIDTKAYFGKGVMTAVGNVNEILGPALVKSGLDVTTQLKDIDKAMIDLDGTPNKARLGANAILGVSMACARAGAAARGVPLYEYLRRECGTESDPYVLPVPFFNVLNGGVHAGNTLAFQEFMLAPTGASSFEEAIQIGSEAYHSLKNVIAKKHGMPATSIGDEGGFAPPLTRPEEAFDLLTEAVKEIGGSDRVQFGLDPASTEFFDAEKREYDLGFKDKQPSKLSPDGLAQLYHHLAKNYPLALLEDPFAEDDWASWTAFTESCRNIPLEIVGDDLLVTNVERVREAVSKKACNSMLLKINQIGSVTEAIAAAQLAFSNGWAVFASHRSGETTDDFLSDLTVALNTGHLKAGAPARGERVAKYNRLLDIEAELKAKGQRVVYAGANFGRRGKAANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV15</accession>
    <name>A0ABR3YV15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eisosome assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EIS1</name>
        <name evidence="2" type="ORF">Sste5346_007268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024527">
        <property type="entry name" value="Eisosome1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28298">
        <property type="entry name" value="EISOSOME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28298:SF1">
        <property type="entry name" value="EISOSOME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12757">
        <property type="entry name" value="Eisosome1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="908"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1289"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="758"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="805"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="908"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1297"/>
            <end position="1315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1363" mass="136419" checksum="12F58B08E8571959" modified="2025-10-08" version="1">MPSTGSTAAQRQPAPRDSGTSYSSRQQQQQAHIPPDHSGRLVYADPRSLPSFPTVGVKLDSTNSAALTASKVKSPPPILDTSGPVNPDSLKAATQAAAAASAALFAKPAAGKAASSPEVRSRNATQSSPINADSPELPSPTLAEDSAAAANNAAAANNANASSNMATKPSGHSTAGWGNSAATQAFRNSQILSAKRASAPPEKPIPEIAALGHQPSLRAAKGAMKQASNLSSNQQSGLASNAAAASLSGATSAAGGGSLSMRTRNRAQSSPLTMRQQKSLSSHYPDSTTSSVLASSPPDPKVSAANALSAATIAHNASARSRGTASNRASYVGDAGSVPYTNMGRQMYTSHPSIGPEAEDQKHTDGLHASAVAMAKKMYNPNAEGGASGSGADGHSVPNVQEQAYKLAQERLEKLHELHAKDREYRDHYVDPNLGASAGDETSRRLTMRGRLRRRRSSSDSDVAADRMRSQEIRNQMSLLSSRISEVEDKRRRDRQNVLLAAQRNVKSQLQDIDEQVYANSGRMPPSVIKSIEPQLTALAQARADAHIGSYPQSHQVDIGGGKFMDRSEVDKIATRRMQPMIDDMHEKQQAEFERQAKLRQEEEERKAEAAMLKARDKEMKDMYKQMKKDEKARRAEEKPEKRRSKILGIPIGFGLGAGAAAASGAGATVGSVTDKAGNIVNGKGKHEATREESTHEAAGKTAADEDMMTAPDTSSNAGDSHTNDISSLGSPGAGPSGAGVGAGAATGAAAGAGAGALAGKSASAEPAAATTTVAADITNASSLATAPVTQPIAGSSAAPTHDVSPTSAPTAAAAVQTPSAAAADNSSRADRNGAPLEKSGSSTSRRLSKLFVKMPKDGNNSNSNTAAVERGRSESISNGPTSKVSGSAVAGGAAGLVGAAGAVGAGVASQAKSVVPGTTNGASSSGAAPATGAQASSTPLSPLSPQSDDSASSPNSNKVKSWLKSRFSRDRSKSASSSGAPASSTSGGKAAATGGAAASTASSTAGGASGSAPSKALGTSAVAPNSEKSFVGGHALAASEVPPNRVGSGSLTMPLIAGGAVGAAGSAAAAGLASSSKGKDKDASGSAANQQRNSINSVNEGYYTPTGSQRQSFAEQGGRRGDSETLGDSGKALDSDATGITAAKDSSEKDAAALAQGQSGHATPIALPVKGFESLGPLTPVIMGPAEGTTTTGTSGGATTASGLGTAAGVAGAAGVAGAAGTAAAASTSHSGNASGLNAPNLDYTSPGNRTSYTSSHYSSEAGVPGHSGSGFGLVGHNIFAHFSGASPAGAKTETGETVSTTAAGATDKGSTFVTVPPPTTGDSGANAGELTPPKAIRDPAGKKSASPVRDSRFLENLEEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV94</accession>
    <name>A0ABR3YV94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007202</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF131">
        <property type="entry name" value="TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045090993" description="Tyrosinase copper-binding domain-containing protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="635" mass="68258" checksum="BAF86A8FA226834C" modified="2025-10-08" version="1">MHLTSSSSSSSGPLLVCAAVISSWLLSVATAQSTTPGIVVGVSTGIDNSTGARPSRININDLYNEAGPHWDLYIQALDMFQRDDMTEIESYYQIAGIHGLPFLPWNGVNQTAGGANSGYCPHGQTTFITWHRPYLALFEQVLARHVRKAAKQYPVETVDAYTAAAQTFRIPYWDWAQDASLPPAVVGPTVNFNGPAGPSTMRNPLFSFQFPNFPFRGGGFGGSLAQFNETKRCTTVSGAAAGVSDEDRASSVMIGDGGQLQDKVYAVFTKSATFEAMATMSNAGASFEEPHNVVHNDIACFSVAGHSGHMGDLNWSGFDPIFMLHHANVDRLYAMWQAINFNDPVFTTSQHGNALYGTPSGPMTADSPLKPFMSPGSVFYTSRSVESIGVFGYTYPEIDDWSLAPADLANTVRVAVNNLYGPGATTASATKKVKRAAKPSSWKLPHVRRATAAADNKKIDTTVVTSTVGSAVQHPDTIIPNAHALSSNDYSIEVGVDRSQLPLPCTIELHLKNSGVTTDLTTRRRTIRIGSTSILSMPQTGISYSTTPLRRALVGEATRRTSPAVFNSNDDVLACLRGVSVVIKTPDGQKVPVSSVPSLTMTVQQRTYTPVSADNQFPQYGPVVAYTVKPQDLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW51</accession>
    <name>A0ABR3YW51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007276</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="57"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="579" mass="63056" checksum="C4F2D0B86082D406" modified="2025-10-08" version="1">MENTHTTTSEHSNKDAAVGMEEVEHAVTLPSNNEAEKAVVEDNEAIHRPRLSDIRFILVLVGFGMAFIGSQFQPLIFAAIIPEIAASLNAHSLLVWFFCTPLVAIGVIAPFIGPLADLLGRKPISLAGVLSSMIGMIVAAATPTAAGFLAGMVLTGIGIAAQELMAITAIVEIVPRQYRGYYVAIMVACFLPFAPGSLYGVLIAQVSWRYCACFVAIWNFITAILIFLYYNPPPRTNAAGLTWGQKVKHIDFIGGILMSGGLVMFLVGFNWGGQMYPWHSARVISFLTIGSALIVIFFLYEAFLAPYPMFPRRLMQHTRTFMALMVVIMMAGINYIPVLFFWVLQAVAVYDSSKIELGIRTLPFGFCILGGALISAVIVSRFKMHLRLIMSAFCIIQVIAIGSLTAVDPYNLNTVWAPLVLGLMGVGGVLIPNQIIITVICPDDLIATATCLTVCLRAVGQVIGLSIFYTQFVSVLTAKTLKIVIPVALQVGIGDLPTLQNMMPTLVSQPYTEWALTIPALNTQEKIDTLHKVVIQAFGEAFPRVYYISIAFGVTAVIASFFIESLGKLMDDHIAVHYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA1</accession>
    <name>A0ABR3YWA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">APE2</name>
        <name evidence="12" type="ORF">Sste5346_007045</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="11">
        <location>
            <begin position="27"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="9">
        <location>
            <begin position="252"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="10">
        <location>
            <begin position="541"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="882" mass="98052" checksum="C0C4D6EA40FFFC5F" modified="2025-10-08" version="1">MCRHSGEDAGGATAVNLGRELLPADVVPTHYDITLEPDFDKFTFEGKVVIDLDVVKDTNSVSLHTLELDVHSVKVSGNGSVVSASPSVSYTEDTQTTKVDFDGSLIKGTKAQLELTFTGQLNDKMAGFYRSTFKKADGSNGIMAVSQMEPTDARRAFPCFDEPSLKAAFTVTLIADKHLTCLSNMDVASETDVESKISGGTKKAVKFNVSPQMSTYLVAFVIGELNYIETNDFRVPVRVYAPTGQNIENGRFSLDLAARTLAFYEKVFGIDFPLPKMDQIAIPDFAQGAMENWGLVTYRVVDLLLDEKTSGAATKERVAEVVQHELAHQWFGNLVTMDWWDGLWLNEGFATWASWYSCNVFFPEWKVWESYVTDTLQGALSLDSLRSSHPIEVPVKRADEINQIFDAISYSKGSCVLRMISTYIGEDAFLEGVRRYLKKHAYGNTQTGDLWMSLAEASGKPIDEVMTVWTKNVGYPVVTVTEKDDSIHLKQNRFLRTGDVKPEEDQVLYPVLLGIRTKEGVDEEPILNTREADFKVSSKDFFKLNANHTSLFRTSYSPERLAKLGEAARQGLLSVEDRAGMIADAGALAISGYQKTSGVLSLLKSFNEESDFVVWNEIISRLSVVQSAWIFEDAAIRESLEAFQRDLVSAKAHKLGWTFSDSDGHIEQQFKSMLFGCAGLNGDKTIIAAAKDMFNRFMAGDTLAIHPNIRGSVFGMALKYGGKDEYDAVLNFYRSSKNSDERNTALRSLGRAKDPELIKRTLELLSGKEVKDQDIYMPASGLRGHPAGIEALFTWMTENWDDLYKRLPPGLSMLGSMVSIMTASFSRPEQIAHVEAFFADKNTKGYDQALAQSLDSIRSKIAWVKRDGEDIAGWLRENGYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWG9</accession>
    <name>A0ABR3YWG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division cycle protein 123</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="52375" checksum="3280F5AF5A38FAC4" modified="2025-10-08" version="1">MPEFHSAPQPAPAAGNEAAEEIRFPPVSRDHILYCSYDYWFPKYRKVCIKSRIIPLPAEFIEYLREDSIILSDESHGAAKSGDDDDDDDWEPSNPTMRHYKTDDEKKYDVFLDEDDSDDEDDNAPPVVRLPPNKRFPELHQRIKDEIAALGGVVAPKLNWSAPKDAAELMEQKNTMKCRTPDDIYFMLKSSNFVSHDLEHAFDGTTPSTSEQTSAASTTAGLGFNPVLVLRAYFDIHTALEFRCFVKQRNLVAITPRDLKYYPYLEGLRSTIIERTKTLFHSKLQFTFPSGNFAFDIYIPETQGHVGDVGDNEADTPNPNGRLSYARLIDINPWAPRTDTLLFDWKELLDLKIPTPFLGIVGDSGVADENQDDDDSNNQTDGVDGEAAEDEDVDSDDDGNEDDYNTELRLVDKDDPAAMNFSSAPYSAHKLPKEVVDASMAGEGGLREFAQQWQEIVQSREQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWP7</accession>
    <name>A0ABR3YWP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Sste5346_007054</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF17">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303041" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="20"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="20"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1892316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="36602" checksum="78141B13EE1B8D91" modified="2025-10-08" version="1">MRLIATVAAAAASVSVVNAHCYIWGVFVNGVDQGTFRAIRTPAYNGPSPHGYANSPVKNLTSVDLKCNVLGDKQVDYTIQVRPGDNLTFDWHHDKRTDTDDVIASSHHGPALVYLSPDPPTEDSFVKIWEEGLYELSEVPFGAGKWATTSDIAANHGHMNVRVPAGLKPGQVSASYLVRAEMIALHEGDASYLKNQFRGAQFYPNCVQIEVVGDGTVELPKGVSFPGAYDYSDPGVVFDTSPLPTTPCATTYQIPGPTVWSGAWPTTTAIEVGPISGPTTATLWSSWIQKSIVTYASYDGSEANILSTSVYTAEWSTTYQTPAAMPTPTAQRDPPDPVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX82</accession>
    <name>A0ABR3YX82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Deoxyribonuclease NucA/NucB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029476">
        <property type="entry name" value="DNase_NucA_NucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14040">
        <property type="entry name" value="DNase_NucA_NucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Deoxyribonuclease NucA/NucB" evidence="2">
        <location>
            <begin position="299"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="647"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="737" mass="75432" checksum="F3A49C3B05BD6CC9" modified="2025-10-08" version="1">MPLKCELGCCTIEFPVCQPDNFCCPEDTTACGAVNPPYCHYPGTICCPEPADTSCPVDTTCCGTEACCEEGSICMDESVCCLPGQVACESWCCPFGSECSDFEGFCELDDGQTSSGFEPSQTKQSSFGQPSSSAPVSESSESTPSISLPSISIPSQSAPSQSPPPSSNPPSSNPPSSNPPSSNPPSSNPPSSAPPSSTPPSSTPPSSVPPSSTPPSSAPSSPASSPPVSSGPEQSSSSPSPTVCKRDESGSCAVSSSSSLTCSISGTPTLVMPYIPDKTDELIENICLGLRKLGFTDRQQLNYAGPGKASANRKLTDCGGGKCCSGQKKATGVNAGKALTCDEYPFASTTQSNKDSWVGCILGFQNTAGGFVYLKNFLRDELKYTPHCPYIMQIDPAFDCTTVLASSIPGCNKKTTKRQETAASSTNGVFYDSYNNSPGTLIIYLGDLPAGSYSVDVTFPAGAVVSRVMIGDVDGNEYNVQDTPTSGSTYRFTAVLDDLGYSAALIAETTSDDLSVVSWSVESSGDTPPFSSGGSTLPSSTTSQPSQTSSQSQVTSGSSTTTIVTVISGVTTTITTCPVSDLPPPPPPTETVSISISTITTCISGVTITTTTTCPVVTASESTLPSLPPHHSYSAPPPPPPPPPPGGFSSSVGSLSPPSEVESNTSPPPPVQPTTPTTEPTQGAPTTPTTPVTEPTSPASSSPSPSAVVTAAASKTDIFATKVVWIVFGASLLFLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z018</accession>
    <name>A0ABR3Z018_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="683" mass="74592" checksum="5C990403E9F8C818" modified="2025-10-08" version="1">MADYNHRRAASELVSYRQAADGTIYRQERNHVSQRPGSSGALFANSTPRMHNKVYVDGNKYANTNFHFRSQSYESPYSWDSYVGGEIPVSAPPTGHSRYGSLVPPEVRAQHMQLALPNSQRRGSESSTSSAISNCTATAGGPSAWSAATTPEAMSPTSPNNSLLLQSPPERTSSKAGPVIQAPPPSPSKTPNHAPQQAFIPCRSARARALSHSAPKRFQNTAIESPVPEEEEQTETRRNSGRLHQKHASHEVNMAKEPAAQPFVSLTEEEAKAVSNLRQRRQQRQLKMTGTPQKKQPVRLRLTPLPPLPLDQQSSRLSCAPSPRTLKSSRSSPQLRDAAGPPPTGPLPPLPGAPNLSQLPPPTPRTPSMPPTPSFANSNVRPPHPTVPPPPPPSRQSVESPGLLSPRRVSPSAEPTPVCEGPQEQGTPWEEELRRHKKLLEQFPTESEERRDLPKLSRSHRSLGNIRARSRSLSRATGVSFHDDAAIAENRLSHHASSFSLRGSKTMRPSTAKSSKDVDHRSREVQPSQSQVNAPHISVFEDDSDEEGDTVRKFVRNLFTRRTRSGEVPLASPNATEYTREVSSGSKHSVSSGKSTEGNGHNDRKKNHSSSSNFSIATTVGGSTVVSTTTSLDPSSAETYHDSCDVEYHAEGNNSTSPRTSSDHSRQHQKGPLLSRMFVRRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z181</accession>
    <name>A0ABR3Z181_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF30">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="20"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="500" mass="54046" checksum="965FB2F81F618D55" modified="2025-10-08" version="1">MEDTAAHAPKPHLTTGNIVSILVAGMGSFLFGYCNNAIAGTFAQTSFTSKFLSGPNAEAITGGILGGFLSGGFIGSIVQAPISQRFGRRAGTATAAVLTVLSAALQAGSVNIAMFLAARTLCGIGAGIVITNVPVYMSEIAPPHLRGLLVGNHATSIVYAYILSSVLALGFSFVDHPYAWRLQYVMLAFFGLLLLASLAFLPESPRWLVERERYDEAWTVLQQLHQSKGGNDTHLARAEMVQIRAQIAEEHAQPTGYWHILKTPNLRYRVYCSVLVWIVGQSTGILVIANLTPVLFGQLGYSTLLQLGLSIVWTVVALLGCFVNSLIMDKVGRVRLMVLGGYLCSIVLIVEAVLQKYFLNTSNTSGINAAVAMYFLFIFFYGSTIDCAAYVYISEIWPTHHRSRGSTIGLASFFLTSIAYTSPATKAFATIGWRYYFVMAAVCLVSSTVMMFVLPETAQLTLEEIAEKFGETVVVRLGEASEKGDALVVDHTEVAEARAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z195</accession>
    <name>A0ABR3Z195_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two-component response regulator SSK1p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MgSsk1</name>
        <name evidence="5" type="ORF">Sste5346_005902</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF28">
        <property type="entry name" value="PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="453"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="177"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="619"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="727"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="672"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="734"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="746" mass="77296" checksum="0DC79521BB80DF80" modified="2025-10-08" version="1">MATPAAQRKVWVRRPGASATLVAFNETDVVDDVREMLLRKYGNSLGRVYDAPDVILRLNPREAHQGERTLGPDELMTRTLDVYYPGGQTIEEALVIDVPIRRVTPNASPRGGPPHAYHLTAVHHHDRGSRHDHRGDYSSHSAMAAPDYFGPGVVPDYYNHGALTAESEYSQATLAPESALTGPGGARGGASASSQHLYPPSPSHLHPTHKTGTIRSATGGAGSGVSAASLQGVGGVGGGGGGAGSGGGGGSAGNSPLNHPHSISILATGQAPPLPNLPSPGGSSRRSHKERPKIHRQLSSVPDDGTGSGREGPSSQINGSGGSGVSGQKGLTASGLKMPIVAPIPGKGGSGRSSIADGLNQKIKGASDTNGVDKDGGKNGVNGTTNGSSGAASARSISSPPRPMSPMRGKRAKKSARNGSGLLNGSTNNADDSHNGGGNNIVQLGPLTVPPINVLIVEDNIINLKLLEAFVKRLKVRWQTAMNGRDAVAKWRTGGFHLVLMDIQLPLMSGLDATREIRRLERVNSIGVFASTPSDSIGVGRDPQSDKLANMALFKSPVIIVALTASSLQSDRNDALAAGCNDFLTKPVNFLWLEKKIMEWGCMQALIDFDGWRKWKEQKLPAQTSSSQTAHADGNSGNGNTGNNGSSDATSSKKSKKSSGHSKRPSMSLAAEGESSETTNTVSSTESPGPGHTRTNSGSVTAGSPGRSPLSKPSISERLAAATAAVEVDNAAMDSEKPEKKEKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1L6</accession>
    <name>A0ABR3Z1L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21638" checksum="DEE9508072AB3E05" modified="2025-10-08" version="1">MTLRICTIDPCTRPAERCAGSYMLCAQHLCTAHLQLEHHTCLTRDTEPYAFFKTYGAAKNKYLSALLAKVVVAALQRIASQARDGVSCTIPALAQDVDDETRLARVSEQFGGQNAHVDFCFEDGVTWLTRLRPDDSLLPPAAVRKRVIESGVATLEFLERTKMPALKVYAWSSSSSDIGTPYVLMEKLSGRPLDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z221</accession>
    <name>A0ABR3Z221_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc ion binding</fullName>
            <ecNumber evidence="3">1.3.1.105</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">YIM1</name>
        <name evidence="3" type="ORF">Sste5346_006037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.105" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102978">
        <property type="term" value="F:furaneol oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052733">
        <property type="entry name" value="Chloroplast_QOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013:SF1">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972438" evidence="1">
        <location>
            <begin position="19"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="65"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="414" mass="43951" checksum="7A942A64CB8BF8A4" modified="2025-10-08" version="1">MSFLSFSAFTSLLTACTAILIAQLYTRSPLAVRHRNTARSVKMKSWEVVKNSDKPSEALRLKDDGVETDHANPLATLPRPKGGDITIKVSHAGLNPADLAFMANIPSWVPFRRRPTPAIDFAGTIVAMGPQAASSKGHKGAAKPLAIGTRVAGCLTVPYVATGHGGLTEYLTVPADMVARQPDNHTSVASVGLLGCAGQTAHLCATDSHARDAFAAATKEGRRPRVLINGASGGVGSLLIQINKSKSRDAHVTAVCSGRNAKFVRALGADEVVDYTQHKSLPEYLATAYADNKFDLIYDCVGSQPLYLQSPSYLQPKGAVLCIVGGGQGSAPFVRNKLLPTFLGGTPRAYKLLALFPSGEQARAVAGMVEEGTIKEMPIDTVFPFEEAVAAYEKLATKRSRGKIIVQVDPTVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z259</accession>
    <name>A0ABR3Z259_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Terpene cyclase/mutase family member</fullName>
            <ecNumber evidence="5">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ERG7B</name>
        <name evidence="9" type="ORF">Sste5346_006430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000250">
        <property type="term" value="F:lanosterol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02892">
        <property type="entry name" value="SQCY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002365">
        <property type="entry name" value="Terpene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01787">
        <property type="entry name" value="squalene_cyclas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF20">
        <property type="entry name" value="LANOSTEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01016">
        <property type="entry name" value="Prenyltransferase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01074">
        <property type="entry name" value="TERPENE_SYNTHASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="domain" description="Squalene cyclase N-terminal" evidence="8">
        <location>
            <begin position="122"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="7">
        <location>
            <begin position="424"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="764" mass="87420" checksum="F05CEB368A34E83C" modified="2025-10-08" version="1">MVQTRSTGIDANGLDQTSTPSKKRGNENLNGPHHDSDADRSLKNPAKRQKLPERTDPLRWRLKDDAGCQTWHYLDDDAEAKKWPQSLADKYFLDLPLNLPSLPTPTNPTESVQNGLTFFEKLQLPPGNWACEYGGPMFLLPGIVIAWYVTKTPISLAYATEIKNYLFARAHPDDGGWGLHIEGESTVLGTALNYVTLRIVGVEADEPRMIKARATLHKLGGATHGPHWVKVWMSVLGVADWGIVNPIPPELWLLPDWVPIAPWHWWIHMRQVFLAMSYMYSKRWVCEETELVRELRQELHTEDYAHINWQGHRNSIAPMDNYHPKSWLLNSVNWALVHVWNPYLRPNFIKRRAEQWVSDLIDMEDKNTDYADLAPVNNPMNLVCCYIRDGADAYSVRRHRERLHEFLWMKGEGLLCNGTNGVQCWDTAFAIQAVMDAGLETDPRWRPMLLSALEFLDDQQIREETPHKEASYRQRRKGAWAFSTKTQGYAVSDCISEALKSVILLQKTPGFPQRIDDQRIFDAIDTVLTFQSPSGGCASYEPPRAGEWMEMLNAAEVFGRIMVEYDYPECTTAVVTALSLFRKHWPDYRAAEIKQFIQRSVGWIKTAQRADGSWYGSWGICFTYATMFALESLYSVGETCANSEHARKACAFLLSKQRDDGGWSESYKACERMEYIEHPSGSLVVQTAWAVIGLLKADYPDVAPIRKAIKFIMSRQQPNGEWLQEAIEGVFNKSCMISYPNYKFVFPMKALGQFHHKYPNETVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2I6</accession>
    <name>A0ABR3Z2I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DBF2</name>
        <name evidence="14" type="ORF">Sste5346_005918</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21776">
        <property type="entry name" value="MobB_Sid2p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05600">
        <property type="entry name" value="STKc_Sid2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF417">
        <property type="entry name" value="CELL CYCLE PROTEIN KINASE DBF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="332"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="636"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="706"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="928"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="726"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="756"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="928"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="979" mass="110213" checksum="5DDD537B10ED7142" modified="2025-10-08" version="1">MASFMANLLDRASTAVSRPETPTKNNFLTPTSTPQGSPSKKTLPPGAYEVGTAHDNSGLGSNGGPKQGNIIVPIPSLFDNAVRLGRPQTSGGGSNVNANSNNTNTNALAPSKGNSLQQPQQLLEDPFAVDDSVVHKKTSVSPANKENKAIGNNGETPVSTTSTAGGAVSGGVDASSAGLIKGKENLQPPTRLPVPTDAASSSQQQQYHGHGHGHAAVSRHELYQQPTRERPNTPNVKKFNTSRGLTPEELEILKRPNVRRLVNVTQLYFLDYYFDLLTYVGARQSRLNAFQSEIPAPPETDEATYNQMWSKYKGRERANLRKRRVRLRHGDFQILTQVGQGGYGQVFLAQKKDTREVCALKVMSKKLLFKLDEVRHVLTERDILTTAKSEWLVRLLYSFQDDASIYLAMEYVPGGDFRTLLNNTGVLSNRHARFYIAEMFCAVDALHQLGYIHRDLKPENFLVDSTGHVKLTDFGLAAGFLAPAKIESMRVRLEQASETSVPFGKPMEQRTMAERREGYRTMRDKDTNYAKSIVGSPDYMAPEVLRGEEYDFTVDYWSLGCMLFEALTGFPPFAGATPDETWRNLKHWRDVLKRPVWEDPNYFLSNRTWNFITTCINSRSKRFSRIDDIYQHQYFAEVEWETLRASKAPFVPELDSETDAGYFDDFTNEADMAKYKEVHDKQTALESMADRDESMGKGLFVGFTFRHRKTGPATNEDGEKTGPTGGSSSPRKPLTNDTFGVPLDRDGPETYGTMFQNQQQQEQHAQQQLRLRRHRGRNAFNNEARFGRTRIPQPQFQGCGHGHGHNQHQNLFTQHRVIHQQRYLQRHNPNPNLNPNMSQLNLHNQYSQNSQLTQHHAMSTMPTVPSMPSMPSMAHLQHRLPQLQQQVYLQNYIRSGDTSYVTSPGRFPSQLASPYDYRQQRQQLLEQQRLGQQPQQQQQMLSNSAMQDPWGVAKSDWSAIAKDVPSTMGKPPGAPRKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4F4</accession>
    <name>A0ABR3Z4F4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF13">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045752727" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="35"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="36844" checksum="57F6D6B027A6E5CA" modified="2025-10-08" version="1">MYWKSLLATAAAVSTVEAATTLRFSCSQLVVERLDPLVNPGTTPSPHLHQVVGGNAFNSTMDYTVHDMPTTATCTSCTPVEDFSNYWTAVLFFRARNGTFRRVSTFGNELGFNAATGGQTVYYLTTGNAKVTAFKPGFRMTVGDPSFRTAAQIRKYPMLTFTCLQSSMTRSGATTDFPKGACPAGIMASVRFPTCWNGKDLDSPDHQSHTAYPSGSACPSTHPVSVPQVFYETYWDTRPFNNKADWPADGTQPFVWSFGDKSGYGHHADYVFGWKGDALQRAMDANCNSDLFANKINCPTLKVQTIEQANKCTQKVQVKEDLDSWLTSLPGGMEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4N1</accession>
    <name>A0ABR3Z4N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_005322</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16207">
        <property type="entry name" value="EFh_ScPlc1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13360">
        <property type="entry name" value="PH_PLC_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037755">
        <property type="entry name" value="Plc1_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="869"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="992"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="796"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="838"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="796"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="811"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1208" mass="133960" checksum="669395B1E48AEF42" modified="2025-10-08" version="1">MALSRSSSRESSGRGHNTQNTPLAGPMMERFVQAQAQERALEQAQALARRSSESVNNGLVSNTSFSSMASSFHNSPTLMSDVPTPTYGSSMLPSPEPLRGRDLGPAPISSFQLPESMLSHKMSETSLLQHTPPPSIHPGNNVNASMSQEASKQNGNIIRRLSNRASKAITRRRPSSAHPNSRDVSVGPGILRRRSDSNNTAPASDIMDRPTFDTDSEYDVDERDDGDSIAASMFDGIANTDASATTNGTSSVNGSVATATAPTPAEVGPVIPLALLHGISIRKVSKKHKRIILTLDAEAGKVSWDKFRPSKSIYIDDIKEIRTGGDIRQYRLDCNIPESDESRFFSIMYTVPGTTNTKHKHFIADTDENFSDWTTTLDAIYKHRQDMIASLMAFNDKAVRSYWNREMARQSSDKLNAQSTTALAGEIDFAGVERVCRNLHIHVPQETLRASFAGADVHKLGRLNYAGFQDFVRLMKKRGDIHAIYRTLASNANLGITRDEFFDFLRNTQGENVDDELASWETVFSRFARRPKASSSSAKDVAVISDGESVISGSEEVPRMSEAGLANYLTSTYNLSMIKEPKEYTFDRPMNEYYISSSHNTYLVGRQIAGTSSVEGYISALTRGCRCVEIDCWDGADGQPIVNHGKTLTSSISFREAVSAINRYAFVKSPFPLWISLEVHCNPEQQRIMARIMREVFGSKLVTEPLSNATNRLPSPSELRGRILVKTKKTQQPTTATLPPLPLQTSSEVIAANTSEFSGRRRGNSLPTTYQKSITLDGNVPSVIYSPTNSQISPLSYSAGQSSPVLSPGYSTPTTPRKSSTPKARLTTVNTITEGEVAREIPSSSTSDCDSGSEKLPTKHKQSKIVPELGCLAVYCVGVHKATPFEDADCKLFNHILSWDETVYERGTKTRDYRQAVYFHNMRYLMRVYPKAYRIGSSNFNPLGHWRRGVQMSALNWQTYDLGMQLNAAMFTGGTDQSGYVLKPRECRQFQVLPNLPGESKPRELKRERKNVNFSIGVVSAQQLMRPVNFPDRRTLDPYIEVEVFMADDKRDRDESKQQPADNLPQTPLIYRTKIVPGNGFNPVFDQRFNFRFTTKYPDLVFVRMSVKLAENGKYTSANPTATFTAKLSNLKQGYRTIPLVDVNADRYMFSTLLCEIHKEPITSVFVPCATDAPEAGTSTNKLKSIRTVFNRTTNLSPKSSIDSGPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Z1</accession>
    <name>A0ABR3Z4Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07010">
        <property type="entry name" value="cupin_PMI_type_I_N_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051804">
        <property type="entry name" value="Carb_Metab_Reg_Kinase/Isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049071">
        <property type="entry name" value="MPI_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42742:SF3">
        <property type="entry name" value="FRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42742">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR MPRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21621">
        <property type="entry name" value="MPI_cupin_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Mannose-6-phosphate isomerase cupin" evidence="3">
        <location>
            <begin position="285"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="371" mass="40318" checksum="3BBED20A8B7208E1" modified="2025-10-08" version="1">MPIILPANQPPRRFYHGGERIRAFRGMAEYTVNGDGPLHEPEDWVASTTSCSGGGKCCNGIHPLGQTRLPDSAGPRGRDGGRLLSDAVIADPRYWLGDDHIHTHGIVANLLVKLLDAGQRLPVHAHPHDDWVRANMEGREHYGKAEAWYILTEGEVYLGLKEDASVDTLKGLTLSQDPSLLERLHRLEVKPGDAVYVPPGYLHAVGEGVLIVEVQEPADLSILLEWTGFNLDGLKDGHLGLGWDKALTAVDGKGRSHEEVQHLVVTKAMRAERERTAAGARSSVFPEASEEYFRLEEIELADNNKKELEAGFSLVIVLEGAVKLSTTGEDGQTLSLTKGNTVLLAYGEGAATLEGSGHVLVARPPKSQPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5G7</accession>
    <name>A0ABR3Z5G7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="277" mass="31573" checksum="64F76710A7A23651" modified="2025-10-08" version="1">MQTTHVQEMSTKNDQDQLSFDNISHPRAPAQSSPVQADGSTQTKNDENFDLKTDDDALCEVPVEAASASPGHTNNLTDLQGLDNSFPGEEYKYMGENEYADENEYVDENEYVDENEYVDENEYVEENGDGDRDEYDDDYNDEHDDEYDYEYNDDHDDEYDDDDEDDDEDEDEDEDEDEDEDEAPFDGRLLDLANWTVRASQDGSWPWSLHRGLIGSTLENVPPTRDVMNIAQNGQVNYIIYAATNDIASTSNCSTMISTKHPGLSRHVRFPSNHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5P7</accession>
    <name>A0ABR3Z5P7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="7"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="59228" checksum="D87F75EF3D730D29" modified="2025-10-08" version="1">MTLSSPIQIETGLVAGIASDQKPNVTIFRGIPFAASTAGENRWRAPQPAPSWDGIRDCSKFGDIAPQLPPGPLYWTEKPPSQSEDCLNLNIWTPATPYDVGAARYPVYVWIYGGKFLWGAGSDNNFDGTSLAAKGVIVVTFNYRLGILGWLAHPELSADCPGGHNASGNYGLQDQIACLQWIQRNIASFGGDPGQVTIGGQSAGSACVGLHLYGPQSKGLFHGVISQSGTRHPRDPLISCLAPSYRTKEQAEREGEEIFVEKGAACVQDMRSMSLDKLLEGNHRDDTTMWGPPPFYRACLDGWLFPRTYEETLLQGTMNDVPLLNGQNKDESGNYTHPDFNDDDLAAAAQAKYGAFAQRFFDLYGSEGSALEQWNAACQDNSRVGPHLHYNLWKKHAKSDIYIYHWTHAPPPRRGFRTDYPVPKAKGYVFFNGSRTGAYHAAEIPYVFDSLWTAPVDPFTDMDRKVADMASDLWANFIKTGNPNSGSNYIHWPSAAEDPDHVMRIGETLELIPNATNKDREEFWEDYFAEQKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z662</accession>
    <name>A0ABR3Z662_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="330" mass="35865" checksum="95D249E94C7935E6" modified="2025-10-08" version="1">MGISKLSRRLHVPSDYQSNSHEDMKVRTIWNGQLPQDLSCLVKEDLAKMTPAQKSICPNIADERFWTDENYYNNDRNLNDDDDNNGLGIEWQPGEPGPLCSSDTLVTPLKGSGHGSLPPDMQGRSPSIVLGPGQCGKGCNDDCTIPKIRSNKSNPYLGIIPLSGLPLPTPRPTSSSKPPSPSSSSTVRQCHFHLKEVFTNSNNKKASDKKAVQITMTGYDPDNGKQSNVDSVWNKDLGGVFAWFAVDSRLPADVGVSLLDCLASGTDAISGSDDSNGPMLYDCNIKFTASGHTWATTDTDKSKAAYCNVGKYDMGSKTPVNRQMDCFYTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6L2</accession>
    <name>A0ABR3Z6L2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004964</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF314">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="22"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="436" mass="48279" checksum="D7B6F16A1F9F5135" modified="2025-10-08" version="1">MGSKGETTNTASRSEANKPSRLNVVVCGGGIAGFATALLLREDHDVTVLESSSLNEELGAAITLSINASRLLRSSIERAGFDKVKAGYVEAEKFQELHWQDLSVILEWQISKVTEAYKEPWWYFSRKDIHAELKRAALSPDGLGTAPRLVLGAHVERVDLENQTVVLSSGERFHGDVIIGADGIRSASGNSVFGKLQTVPEGLSAYRCMIQSEKLKDNPATEILVDSTKVLMLIGPDRRIVAYPCSNWNWINFVCIFPDDEDRRLQWHDTVTVEEMVQKFQDFHPSIPAALSMASNTGMWRLRDRVPLSTLAKGCYAIIGDAAHAMGPHQGQGACQALEDAEALRIILKGSTPLDVPARLKIYDELRVERIAKVMEYTRAMAPSKTGSLEVNHKTTQTYSDYYWSYKITADAVALMRTHGHALKIVDEATGKIEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z757</accession>
    <name>A0ABR3Z757_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tmem1 family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055505">
        <property type="entry name" value="DUF7077"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022233">
        <property type="entry name" value="TRAPPC10/Trs130_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056913">
        <property type="entry name" value="TRAPPC10/Trs130_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23274">
        <property type="entry name" value="DUF7077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12584">
        <property type="entry name" value="TRAPPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23036">
        <property type="entry name" value="TRAPPC10_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24965">
        <property type="entry name" value="TRS130_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="6">
        <location>
            <begin position="119"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="6">
        <location>
            <begin position="301"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7077" evidence="7">
        <location>
            <begin position="1081"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 C-terminal" evidence="5">
        <location>
            <begin position="1437"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="201"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="626"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="735"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1596"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="510"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="744"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1665" mass="180033" checksum="94FF422BAE5C0E39" modified="2025-10-08" version="1">MEQPFSTSKVTVEYYDPHGLYRLLAPGLLKRLPLRHLHWQSHSGPLRSIDTLHVELVSAESNPPVAGGATARTVPKTTGSDAPPTDDGFQTATVGGRQGSLESTPTTTAAASTSTSRPPERRHQIPGLRRTPYLKLLLVRCDDTDTYKSQTRAEIKDWVKKNTHQGSSGSSNRKASIPPVENHDAFEWMIVHVVLPNSQAYNQPRTSKSSSGGDGTGSDSTTKTTSRWGKNSSTILERLRSDFNIAGDSKSSSSSASASTAAIDRVSQIRVGINDVPYELLPRVQSTGSGTTPPTGTGYVESEREAQAAWTDVVDKLKSRILASFDVRVSQYEDDIREKDVQRTLPGWNFCTFFILKEGLARGFESVGLVDDALVGYDELSVGLDTVIQEQHALTASTLLSFTDDLKTAALKAINGGDGDDSEDSEETVNLQAATATTGTSESAIPISATKKPYRDLILANNVSVFDFRCYIFARQIALLLRLGNAWATREELLTKLQEQQEATMHLTPAAAASHAAASTSTSSSSRLSDDPENLSMLAEICRRTLEFVPAVSQVMREDLLFSLTTDGETLPASSLQIIDNMVASFAFSIAQQILAQTSTRALPIPPSTMTLASDNTQELKVSIPEPKTMMHPARTSSLETRGQQAPTGRGAGGGRPPLSPGIFPGPGQPQSAHDAESSSRFLKAGLEDLAARRADLYMLSRNILQKGGEKLGWSNGWSTAPVLSAVDDDNDEMEEVSLDDDAPATSSPSPSSPSTSPSSPTAGIEDLLLRTALESNTGFYRLYEALTDKALRHYIVAGHAHAVNANRADLAVLKYHLKDYLTAAEHFYETTPFFGENSWGLLELSMLLMYARCLKEMGRNDEYAWRLLKFLTKAADAERQRLEERASFMRRAEKAEKKHPPPSAVQGCLADLLSASTSVSGEMRVPLINFFRLVAVDGPPVFTDGEDSFSITLHLDSLLVDPLPVDSVKVRLTQTSSRGQAREIWLETTDSETEAITLGPGTGRVQLHSRTIIPGIYSIDQVRITSKNLVIFHDRDGAHTVQRLSTGAAAAAPVSTVSTSTTSAANIFAEPHLVLYQRTDALDVQLSTSKDLQLDKNNFLELVLLTGWNDIQHCEMKIRAATGGLRLITTEAKVLGTSGYNFSKPVEGGIVCFDNVPANTSLPISFPFSIEQDVLELCLKVDVTYTTRSGATFHFSKAPSVSTSLALGVNVQDVFKHDALFSRFTVSTATASPLRVFRSELLESDLFTAQLGTEAPNASGDGSVDHSTNLPVVFPKQPVSLLYKIVRKPLSGPLNAPPGKDTKRTMYIKLHYSVFQDQLDAALKASLGEAFTKTASLAHFAKLASACVLRHVHASLSPYDLEKIALLNEMSTSVLAHVNWAREFPGLGPSAIDASKSKADDLAAVIYAWQKKHTVLAIPPADPSSLTTNVRTILIPVDIPSITIVHTADIQLQGPFGAAVSADRFPSDEEDDSEDEDDVSMPIFCVNQLLPATLHLRWTRIWDTGDAESSEAASSLHDDLEFSFEVSAPTDAWLIGGRRKGHFVIPAPDADGSTIGLSSTPALEAAIPLMLIPLREGRLPYPSVEIRQVADASGHHAESINGNGNVQEHPAGHHCETDYRNLGETVHVVADRTRLTLSLDASGPGGGPLVLESERAQVAGRVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7E4</accession>
    <name>A0ABR3Z7E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB7</name>
        <name evidence="8" type="ORF">Sste5346_004622</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04462">
        <property type="entry name" value="S1_RNAPII_Rpb7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="7">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="78"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="171" mass="19087" checksum="8A72599E60AD0B17" modified="2025-10-08" version="1">MFFLHNLERRVTLHPSYFGRNMHELVTTKLLKDVEGTCAGNYYIISIMDTFDISAGKILPGNGLAEFTVGYRAVVWRPFKGETVDAVVYSVNPHGFFAQAGPLRLFVSSHMIPSQVKYDPNATPPQFADNEDYKVEAGTHIRVKIMGTRSEVGEMWAIGTVNEDYLGPLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7V8</accession>
    <name>A0ABR3Z7V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF153">
        <property type="entry name" value="AFLATOXIN EFFLUX PUMP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="20"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="57173" checksum="E98593104FAE9BCF" modified="2025-10-08" version="1">MVAEATDTTVYPSGMKLALIMVSIYVAMFLVALDRLIISTVIPQITNDFQSAGDIGWYGTAYMLTLCAFQLVFGKIYQNFSVKTVFLSAILLFEVGSALCGAAPSSIAFIIGRALAGLGAGGIFAGALVIIVHSVPLHNRPKFQGLFGAVFGISSITGPLIGGAFTDHATWRWCFYLNLPLGGVVLVVIFFILDLPASPESHKRTLHEKFRQMNVPGVIALLPAIVCLCLGLQWGGTKYAWSNGRIIALLVLAGVLLIVFSVIQVVLPDQATVPPRIFVQRSILSGFLCSCCTGAHMTLMVYYLPLWFQAIQGVSPVSSAVHLLPMLLGMLVATVGTGFTVSRLGYYTPFLWVGSCLSVVGAGLLTTLKVDSPSSHWIGFQVVYGLGLGASTQAPNMAAQTVLPKADVAIGASLMFFGQQLFSAVFATVGTTALDNQLATRLQSLNVNISPEQIQTTGATDLLENLPSGMHAAALVAYNAALRVCFIIALGMAALSVLGALGMEWQSVKKDINKNEKVTDEEAVDIETSKPREGEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8L0</accession>
    <name>A0ABR3Z8L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18785">
        <property type="entry name" value="Inv-AAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="181" mass="19978" checksum="70CB76E48EFD9CAA" modified="2025-10-08" version="1">MDHHLEYMRQALDQARKSPPKPSNFRVGAVLVDAEDSQVLSTGYTLELPGNTHAEQCCFMKLAAENGMTEEELPSLDENVLPRRLALYTTMEPCSFRMSGNLPCVQRVLRLADSSPTTHREVTVYSGVMEPDTFVSKNMGRQTLEAAGIQFVHVAGLEDEILAVATAGHKTKSGEPKQETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8X7</accession>
    <name>A0ABR3Z8X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-ketoacyl-CoA thiolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_004237</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="31"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="10">
        <location>
            <begin position="290"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="44102" checksum="C10D5BEC59263020" modified="2025-10-08" version="1">MAAQRLQSIASHITGTREGVDRILEKHPDDVVVTLAFRTPLCKASKGGLKDTPVDTMLFKVLQHAKERMNMDASLVEEICLGNVHEGKAAYYCRAAALAAGFPTTTTASTVNRFCASGLQAVQAVANQITTGAIDVGMAIGAESLTFAGPRLTRPFAQAILDANQDAADCMNPMGQTSEVVGAEFHITREEQDAYAAISYQRAEQAQKAGWFDDEIVPITVTDKDGKDTTLTKDEGPRWGTTVESLSKVRPAFPEFGNRSTGGNSSQLTDGAAVVLLMRRSKAQELGQPILAKFCAATTVGLSPRIMGVGPSIAIPKLLQKLHLSMNDVDLIEINEAFASMAVYCKKELGIDPDKLNVRGGAIALGHPLGCTGIRQIVTGLSECRRRKARLLMTSMCVGTGQGMAGMFVNEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z961</accession>
    <name>A0ABR3Z961_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sam and ph domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="185"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="749"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="954" mass="103343" checksum="EE04BF7AE85BADC4" modified="2025-10-08" version="1">MQQRNTLLLHESFFSLKGVQDRPVSVATEFMESDFEEDDIVSDDESVDNGGNNSPRGSMNSSGQPSFTTISSYDEVPTPRSSRMPMDLPMPIDMAKPVEGPRGPHLFRISTLSAEFQNALSLSPLTPKAPSSAAMAFHLQQSHHNVPLPHGITPMPPTRQQQTQARSGPFRFSHEELETDSLASWSPEMVAQWMLNAGIELQVCERFIENDITGSILITLKFEDLKELGIPSFGVRTNVWNQINTMKNVKAVEPRPDTPIEDEPDREVRRELRREESVNHGNNNQNKPMRRCASSRRKKPIRTSPGLPSSGDDTITPMESVSIVGIEQMMPKPHQCSKGENCSKWRRNQRMMEAFKKDHPFVDMDKGGVIMVAGDPGNPVTARAMIPNDEVFRPVSDAIPSVVASSDVMGPGIIEAPLALEEGSLRAIQSRDPQDNVRQFLDFQHQHATSSEVPPTPPFELFPARAQQPHEGLRTLPKLAIPSQLRQTHTVPDNQAFLQFQQQQQQLQQQQAQQQRLSAGSEPGVVPIVVPSSYPLSAETASAAPTSTTSYTNTAIEESPGHTPTAPYRFGTPFSEVDVPVTAVPLGPVARDASQSVPPDMNYRAPLTRTMSRASARRPSFPVLPSLAENQVTAAPRVTPAGLPRAASAMGYRPTYRSVSPEGLGNDSGIAGARPMQPPPRVKYPWSPERATFEKAIAPLSLINTTLNNSSSSLASASTGTPGSAMSGASTALTSAGSSMHSATAAPGGITYQGEVKKRKTKMLRHEWNDRYVTLKGTRMAVHKDKASMHHSTLEYVDIDDYAIACSTMAASTSKLNAAFKAMNIRRGSADNAGSGSSKNDVAAFAFQLIPQDAKGGVRLKKRDSAMPGSGGNSILTSSSASTLSSGGAGSLVSSSSSGNPPPPPDAVNGTGKTHHFAVKNRDDRIEWMRELMLAKAMRQKGEGFEVSVNGNMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z986</accession>
    <name>A0ABR3Z986_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TAF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017246">
        <property type="entry name" value="TFIID_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="227" mass="22953" checksum="2EBFB4E85FA0F5AE" modified="2025-10-08" version="1">MATNPASERTGADQEATSNGTGLAATNGARPDTVGDDAAGGDAGGAGASADAASGPNPPPATVDARPITTAKDISLKDFLNKMDDYAPIIPDAVTNYYMTKAGLPPPPQTDPRLARLLALATQKFVADIAADAYQYSRVRASNSGGNSNNPMGNLGTAAGFPLPGQPNAPGTSAKDQAKNAALGIQRPGFGGGGQGGSQNRTVLTMEDLGMAVGEYGVNVKRGEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9U8</accession>
    <name>A0ABR3Z9U8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingolipid delta(4)-desaturase</fullName>
            <ecNumber evidence="8">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DES1</name>
        <name evidence="12" type="ORF">Sste5346_004173</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:46544"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:31488"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="1.14.19.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017228">
        <property type="entry name" value="Sphnglp_dlt4_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="11">
        <location>
            <begin position="59"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="405" mass="44981" checksum="1A31632DFD6A2601" modified="2025-10-08" version="1">MALTAPPATASAVQINGNGVKSRVKATAEAVEETKANGHANGSNSHSNGAAPSPIESQPKYRDFFWTYTEEPHRTRRLAIIKAHPEVTKLCGPEPLTKYVVVGVVSLQIFLGIALAQAGYTFFSWPFWAVAYVVGATANQNLFLAIHEISHNLAFRSPLANRLLAIVANLPIGIPYSASFRPYHLTHHKSLGVDGLDTDLPTAAEAIFLDSILGKAFFCTFQIFFYALRPMAVMRIPFTKIHALNVVVQGVFDYVLVKSFGVQPLLYLLLSSFLAGSLHPLAGHFIAEHYVYDTVTPDAKNPENNIPIPETYSYYGPLNIFAYNVGYHNEHHDFPAVPWTRLEKLRATAPEFYDSLPHHVSWTYVIWRFIWDDSVGLRCRVKRKTGGRLVGGAKVAEWTETEVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAJ2</accession>
    <name>A0ABR3ZAJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20152" checksum="20854B5B14AFC05E" modified="2025-10-08" version="1">MYQYPQPAMYVEPPKKKSFSWSTVFYTTFGLLALATNIPIAVVAAKLLHRWPAFFHKAGVPLAAAIIAIVADAMAILFFAKRYRAFWLVVPLDLLVAIMAAVGVFSLLGAGFSSSNMPLTDAQAQMMADWSLDQDLGVIFSGLVCGVRVLSLFVNSILSCLIFTRTRRHEPTTVQAIQTTELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBA7</accession>
    <name>A0ABR3ZBA7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps23</name>
        <name evidence="6" type="ORF">Sste5346_003755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="145" mass="15885" checksum="1066D643E6FD5155" modified="2025-10-08" version="1">MGKGKPRGLNAARKLRNNRREQRWSDLAYKKRALGTAFKSSPFGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVGLLALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBD7</accession>
    <name>A0ABR3ZBD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_003841</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046227848" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="24"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="382"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="464"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1897985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="536" mass="58036" checksum="F3AF9393BB88D535" modified="2025-10-08" version="1">MKIVTQVLALLLPALLMPQLAAAAVNGAVFGDLPSCALTCLISSLGDSACSVTNTTCMCLDTKLQDDSTTCILANCTTLEALSAKNITAIGCDQPVRDKSNTFRVTSTTLAIITGVFLVTRIAYRIFVAGSIGWDDWVAMISFFVGVPSSVINIQGLAANGLGHDIWTLPSAEIYRFIKFFYIIEIFYFTDVTLLKLTILFFYLRIFPTKGVRRIIWGTIGFVVVYGLTFIFVGIFQCHPISYYWTNWDGEHTGTCLSVNAIGWANAAISIALDLWMLAVPLYQLRKLRLHWKKKLSVGVMFTVGTFVTVVSILRLQSLLSFANSTNPTWDNYEVINWSTIEINVGIICACLPSTRLILVHFFPRVLGSSSLRYNSNNHYYDQDGNGNSQRHGGIGGSNNRGGGGTGGAGSRVRSIPLVSTASSRHQKGTNTTITTINAHDEEDDLGMMHEGRFGRSNSAAGIHGPLGGGGAQHGQKESIGGTGASGPGGILYQKSYAVEYGSEYNDEARLVYERGQQGNSSKSDLKSSRGSESSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCB5</accession>
    <name>A0ABR3ZCB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21121">
        <property type="entry name" value="Nup49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="324"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="47165" checksum="C4B863E288089F4D" modified="2025-10-08" version="1">MALARSASVPGGLSINTGAANLFGSPATTSQGPASGGLFGSATTQTTAKPAGSLFGAPATTTAAPAASTPSLFGASTAATTAAPATGGGLFGGGATAAAQPAKPALGGLFGGGSTATTTASPATGGGLFGGAGTATTTPAASAPATGGGLFGASTAAAATQPAASAGGLFGVSTATPAAAAPSTMSGGLFGASTAMQQSQQQQQQQQVVPGVRIDLSNLKGTTRFNDLQESLQKDIIAFDSMIQSFIEQKNQVEAFLPAHRESLEAIPGDVRFVARKYDGVSGAMASDLQSIQALRETVKEDADHAQLSFKALDNQKLPAQFHTSGLWSTTGGPKKNGRGRDGARGGDDGSDRKAGSDRGGDSGGRTDLINYFSHTGDEIGSQLRKLESNLGEIEVHMYSVQAGLLEQLQKVAASSNGTSASDANGEGSSASDKVAELAAVLRDFEESILTVASVVGTARESMTGLQLGGFLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCS9</accession>
    <name>A0ABR3ZCS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581">
        <property type="entry name" value="D-ALANYL-D-ALANINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="57318" checksum="2A1475A19F05D031" modified="2025-10-08" version="1">MDGSRPSDGKGHVRNKSSTKATRPRSSTKGPLDVDDPLSQSTLSIQPQAAPTSTSPSSQLSPLSPPPQTASVHGLTPSRYTSARRRSPGPGPGSPMSQTSQQSPPPSRGGGGAASGLGLSIDAAVSTKSQPPPTPRAKDFIYLLRPEIYHPLPATAAGANVPQPFRISNRQPNPDESVGFADSTDLSDLLAAGHFRAAAIVAARQLVAIPDPTDYARIFSLLYTRLACLLLIDATSLAAQEAKALEDLNSPFYRGELDPNDPSGLPPHLVPWELRVLHVRLQALGFGDPRRAVMSYYELAREARVRIAAALATHDNSARELWKARLSELGIQVAGALIEMDDMAGAAAHLSNMSSSSSSSSSSSPSSTTTLSSRRIDMAKALLWLQLGDVDEARAAMEQSSSSTKEDDSPFASNKSGESGDLAPRVVSTLCDMADGEYKTALEAWRALREDAPDDEMIGVNLAVCLLYVGQMQEGRTVLEGLVDAGYSSHTLLFNLSTMYELCTDRAKAMKLNLAQRVADQTPAEGQGWEKTNADFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD14</accession>
    <name>A0ABR3ZD14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003656</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF41">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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</entry>
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            <taxon>Pezizomycotina</taxon>
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            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
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                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
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                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
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            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
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                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
    <sequence length="1305" mass="144017" checksum="F27D867E1CD7DDBD" modified="2025-10-08" version="1">MADDIVPDHNIAEHEEEAPEIILDKSTVEEATESTESTVTEDKDTLQSSADAGNSNDVANVIEAIDAFLADPNDLGEESQTEVQVEQEENDTHNESHAESLEASICESYSDDHDDSHIEEEGVKVEDEPATDNLTTTNAEEEQADDTTEAHTEEAVEEVAEESIEEASEQDNTPLVEIRPRDLSATVEDETPEELAEELAEQASHESTEPQGEERNVEEEHDESHMAEPFEEENVESHEESFAQSVDNSDDQSEHEHEEKADEVHEDHSIVEHDEADVSITESASSHGDESQHEHHDEDQAHDHEHHDDDENGETHEETQNDDNTSRRTSASSSRSAVSNISNRRTSLRTEALIQAAARAVVAKINEKGSTDSHFDIMRAMSESHESIMEEATEAEHHSTTDEEGENDHEGEAELDDDDVFSDRSPRSSLGSFEHNSGASNNGVDEHQKMNIHSTSDDATEHQESEDEHDYLEDTGSVTYHRETSHYSPRMSGVSGISRMSQYEQHQEDDDEEYNDGDDYAHHTIRGTPRAAFRTPSSVRAIQMSSPSPSVIFGVSPRSAARRRRLGTGSGLDDGQSMGSVGTYSSLPGSPSKNHTPTRFKVFRKPEPAPLVLLHATLMPTRWVWSDVLRTLDESISRSSSDRPSSRSPSSMGSPRKSRGKNDVSLHDEDAAETASFEPSAALKRLHGAWCQLQDYSLGADTVAERGVLLPHPQNDYEVLEERLLEALELPVRRRARILECGHYLGPADDEDDEDYEDEDGYYNERAEEDESSKRHWCTTCRSDIRYESLGAERVFRVKVYASNGLMTVGAWAACWSEMERVDVEIEPIVADPALLRELNQLRTQQQQEALRKQEEEDAAAEAAMHEEEEEEELHEEELLHEHEEHDNHDQQAEHEEHQVHDETARSPPAVDHFHLEVPSVIPVSPPLRDSPVEPPFITTTDHASDADRRRREAEDRLREIYGRTPPQMPHSAAPASHSHHVESTRLSDVPETVETATTRDMNDMNDNHSPYGPSPPSPSAEAYERREERRSRQFSSADRGFSNEPDVSAPHAHHPQAPYESASLPELLLAAVKVFLRDSKHVAITVLSIIVIVLATLRAPGGAGDQGTTHSVQSQAHGVQPAMGYSYQPVKGVSNGHIDVAQKPVEASSVVMSESSVVAEIASSAVAASVDTLVETVVEKMTVKVYETVTETSTETATQTTVATIATEEPVIDVSSTVIAETATVEAIESAVSEEPTSASVLAEPIVEEQKNTFETEVEVESSSATSAVSLPALVDASSFFAATDASTSAAKPTALVVEEHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF45</accession>
    <name>A0ABR3ZF45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AAA ATPase cdc48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CDC48</name>
        <name evidence="8" type="ORF">Sste5346_003224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19519">
        <property type="entry name" value="RecA-like_CDC48_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19528">
        <property type="entry name" value="RecA-like_CDC48_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="7">
        <location>
            <begin position="47"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48" evidence="6">
        <location>
            <begin position="147"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="259"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="533"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="805"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="830" mass="90928" checksum="340055C00F2ECCDE" modified="2025-10-08" version="1">MSDQPETKPDVTPKKHKVNLNDASGAERRDDDDTATAILKKKKKPNQLLVTDSTNDDNSIIMLAPSTMDTLQLFRGDAVLVRGKKRKDTVLIVLSDDELDEGSVRLTRVARHNLRVKHGDVVTIHPCPDIKYAKRIAVLPIADTVEGLTGSLFDVFLAPYFREAYRPVRQGDLFTVRGGMRQVEFKVVEVDPPEYGIVAQDTVIHCEGDPIQRDEEENNLNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKSIGIKPPRGVLLYGPPGTGKTLMARAVANETGAFFFLINGPEIMSKMAGESESNLRKAFEEAEKNSPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVMAATNRPNSIDPALRRFGRFDREVDIGVPDPTGRLEILQIHTKNMKLGDDVDLEQIAAETHGYVGSDLAALCSEGAMQQIREKMDLIDLDEDTIDAEVLDSLGVTMENFRFALGVSNPSALREVAVVEVPNVRWDDIGGLETVKQELKESVQYPVDHPEKFLKFGMSPSRGVLFYGPPGTGKTLLAKAVANECAANFISVKGPELLSMWFGESESNIRDIFDKARAAAPCVVFLDELDSIAKARGGSVGDAGGASDRVVNQLLTEMDGMTSKKNVFVIGATNRPEQLDPALCRPGRLDSLIYVPLPDEAGRLGILKAQLRKTPVADDVDLQYIASKTHGFSGADLGFIAQRAVKLAIKESITADIERTKAAEAAGEDVEMDEDQEDAVPELAKRHFEEAMQMARRSVTDVEIRRYEAFSQQMKNAGPGSYFKFPEGGIDSAGATNPAGAAPEGFGDAGADDELYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFD7</accession>
    <name>A0ABR3ZFD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRO2</name>
        <name evidence="9" type="ORF">Sste5346_003192</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="453" mass="47494" checksum="CA314A80C95884FE" modified="2025-10-08" version="1">MSLTDAAPAEAARAAKAASHILATLSADERNDALLAMHDALSASRDAILAANAEDLAIAQREAAEGRLNPSLVSRLDLGRKGKWEDMLQGILDVRGLPDPVGRVTLRTKLDDGLTLERVTCPIGVLLVIFEARPEVLANIAALAVKSGNAALLKGGKESTQTMLAMATALAKSLEGNSRVPPAAVQLVTRRDVVKELLALDRDIDLVVPRGSNELVRSIKAGTRIPVLGHADGLCSTFIDEGVVDAAQAASLLLDAKTGYPAACNSLETLLVHEAALTEPAFAAASQALVGAGVTLRCDPTTKAALLEALKGEESAAVKIVDAVDDDFDTEFLSLDLAVKVVPSLDAAIAHINSHGSHHTDAILTPSEANAEKFMAAVDSAGVYWNASTRFADGMRYGFGTEVGISTNKIHSRGPVGLEGLTIYKYKLRGSGQAAGQYGDGKKQYKHESLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFG2</accession>
    <name>A0ABR3ZFG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002845</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="9">
        <location>
            <begin position="139"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="8">
        <location>
            <begin position="516"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="560"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="490"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="729" mass="80898" checksum="F0188815CC1E4BD7" modified="2025-10-08" version="1">MDARGPKRRRVSPTRNGGGDDTKNGIDKSYLKNAANWSLEENYAERSRKRSKKAAKAEKAIDRLPIRTADGMMRPLASEPTDNDAASDDEDPFADSGDDKEAEAAKTKPKNDGSGARKAAARIQEQNSRLPERQQIQNAKEELSKIALKLNENPEENGSAFKQLAQVSQQYTSITVQKMCLATQLSAYKDVIPGYRIRAFGEEGAVPTGEKLSSDVRRIRVYEQSLLAGYQGYLRELMRLSKLRPSEAAAKNGAGKRSKVAKNANSLADAALACACSLLNAVPHFNFREDLLKIIVGKLSTRRVDASFVKCRLALETLFREDDEGRPSMEAVAMLSKMMKARDYWIDESVPNTFLHLRLLSEFSGKGSQDSVERSSDEPKNKKKEFRTKRTRKLMKEQKALDRDMAQADALVAHEERERMQSETLKLVFATYFRILKLRTPHLMGAILEGLAKYAHLINQNFFGDLLEALKDLIRYSEEDATREARTADGEDDDEAANGADEEDDFAVSRNPSREALLCTVTAYALLAGQDAHNAASDLHLDLSFFTTNLFRSLYPLALSADIEKRANSLQQRLADAQEAANSEAAAATAAAALSQKNGVKVNLQTTTVLLIRCLTAVLLPHYNIRSVPPLRLAAFTKQLMSASLHVPEKSSQALLALLYDVAHAHSKKISALWNTEERKGDGSFNPLSETVEGSNPFATTVWEGELLRRHYCPKVREGVKALEKNLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP0</accession>
    <name>A0ABR3ZFP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB/POZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758:SF2">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="64273" checksum="7A744D6790F61AD3" modified="2025-10-08" version="1">MSNLSSGNQTPRAGSLSTGHPTPGSIATPGLPANNGINLSNNGNTGNNGHPQIAQLPNFPPTAATTAANTTAASSTTASRPSATPRNTVTAPRLTESAVQMAARIPNILPHERVFPIQIGCELFKLSGASLSSDAPSYFSQYFECQIKTAEAHGVEDVGSAIRTLYIDRDPATFRDISLHLQGYHVQPRDGTHFVRLFADAQFYSLPRLISQLYDESIFMSIGHREFQIPRDLFQDPGNLPNYFSLGFAIFFSSPDDLFPGLDREGLIRPPSILPPAVPGRSADTFEELLHLLRGYPVSIRDETHRQTLLRDCRYFNFKGLEQKLIPHSLTYNLARLRYEMALRVEDVLKSGISVANEPTLVDPLAGWVNYARPFVDDKPAELVLEIGSENTKLHFFPPASTTSVASPTPGSTGRHGTRAEFFRDTKIRIARLFEVISTKLNLPPTTQPLGLLMSKGGASSQPPSPGNTPLSDDLVRVVLEPETAITLDGRPFALPETLADDDSATDAVLSPSGGGEPGPSRKRRRVDYAALSGGGSAVPGGSAGTAWTIKTGLWRLRIQGVKNGKSAVECVLVGVKLDAMSSELARNQERGFLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFS4</accession>
    <name>A0ABR3ZFS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear polyadenylated RNA-binding protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NAB3</name>
        <name evidence="4" type="ORF">Sste5346_003163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052600">
        <property type="entry name" value="Nuc_rcpt_coact/corep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23295:SF6">
        <property type="entry name" value="NEOSIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23295">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="484"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="559"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="811"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="560"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="824"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="969" mass="100955" checksum="A162767F2D046AB3" modified="2025-10-08" version="1">MSSIPEAPPDEAAPSPDAAITAIPAAVNADVDAAIANGETLPGELPEDDDDDLYSEGEGEVVLNTAEHTVATVDGAEQQDEVNDATHEAEADARAGVKVGADADTDAEAEAVDNAVDASDEAYASNTQEAGNDPDADDVKAADAADENKAEVNEGSTEAQPSAADEAVPGTVPAESTPPTEPIAQAATKESQPDADQGSAVDAVDAVDAAAAAAADDEPSAPDASADAPSQAVAPEVETEAASYIPLVDDNDAEEDGEIVEEDADVDADVEDSASAAQNGASSSSPLPYIDDIAMMDTGELGDIQPSAPTESSFTSSIQAQATSATSASTTNDSGPGIDFDKMIDAISGNAAKDTAKPLITVTGSQVPIGAPKGPANPFPRPPTGPARMTGRFANNPNLPNAPKVSAAGTVPHGIPPQFPAAAGGRRAQAAARAAQGQGQPPTAPRQANNNRERAAVDRAYHAFLNEEKIHVAEGKWEAFPEGSRMFVGNLSQERVSKRDVFEHFHRYGRLAQIAIKSAYGFVQYHSAAEASAAMRELEGVEIKGRKIHLEISKLPQITKGRERESGLVGRENDRARGGKDRSPERAKNRGGRDRDGDRYDGRGQDNSRRSRDDHYAGSPNGHGMSPHHGHGRSDSYGRGRGGRDDYSRRSRDRSRSPSRHGSHGDGRGYRSRRSPSPYGRNRDSSGHGNADALKTRYGSDVPDVQLLVAQGLDREFIKWVQVPFHERGLKTDVILLTPHTPPRDSIIQVHVLEGVTAVVDLDTRSQANGTIPVQVFNRLGGVSNIRFDGYQDLTPSVAADVVVRAKSATAAQQAPRYPPHQPPYSQGYQAAPSFSQPYAPPPTTVAPGNGIDLASLVGQLDNATLAQLLSAIQAPQAPQATPTCGQPPAAPQYAVSGNASQEAQLAALLGTLGAAAGAPPAPAAAFAYGSAPAPYGAPPAPGYQTALPQGLDEQSIQALMAHFAQSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGJ9</accession>
    <name>A0ABR3ZGJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="203"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="465" mass="51177" checksum="1BEB6CA3F871D784" modified="2025-10-08" version="1">MPRHRGFSTSNLLFRPNGADNEGGGGKSTPGKDTKNTRDTKNGITPATPSAAALQAAKRKPRSAGAKHSLRRVAVIAQQPSGSPPKKIRAEEARATEVDEAATLDSPRSPSTRVPRSRREAREATEAEAEQEELDDGSTIISAVCMAESFDMEKVMTILEDQGYEIDPDGSGFESHEVVHARKWWPPPADENASEDEWREVDLFVFESGTLVGWGLPADAVDVLATSHLVAAAADPFLDLRETETLDFRRDAARENSAMRGDVVVLGTRHEAAEGDRLATTRAQIAFSSGLARSTKLAVLERSFTDYFESTRRIPEILAGRKSGGRDGGGLGHISQKFILQKTGELLSLRAQLNHYRELTDALPDIFWDARAELGLEGYYEQVGRALDVGVRIKTLNQKMDYAQEIATVLREISSERHGTRLEWIIIVLIAVEVVFELRRVYLDLKEGSGEIKESKKAEEAVSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGV1</accession>
    <name>A0ABR3ZGV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">MED8</name>
        <name evidence="11" type="ORF">Sste5346_002801</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074:SF9">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10232">
        <property type="entry name" value="Med8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="141"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="227"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="327" mass="36528" checksum="029C5D44BFBEEEAF" modified="2025-10-08" version="1">MDSDDTALGLTEKDLQAIDTVRARLYQLTNSVQRLKGDVLMGGGRGDGVDSSLLPTPESIQNSAFVLQQNLTSLNDAMGKHAELFRRIVVHPDPMYPGRTEEQILTSLLRKKLEPDVEQVAERARETAAARGIGPFSFAESLGRRNKGYDDNVNDDDDEEEEEEDNDNGEDPIENDDGPREPFGLGDVWYEAHQWCLDRLRIFIQEETSDVYTKEEREIGVENVRTGLRRSLEEDDEDDEDEDDEDEDEDEDEDNAKGADDDVIMIDDGAPKPAAAQTSQPAQPPVGPAVEPEVLLWLAARGDTDLPRYVDIEWQRAAAAAAAQRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH31</accession>
    <name>A0ABR3ZH31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_003244</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02878">
        <property type="entry name" value="GH18_zymocin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006970">
        <property type="entry name" value="PT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04886">
        <property type="entry name" value="PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="13 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="LysM" evidence="17">
        <location>
            <begin position="377"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="18">
        <location>
            <begin position="524"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="978"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1178"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1192"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1213"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1228"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1898834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1599" mass="171613" checksum="4F7BEE084D616813" modified="2025-10-08" version="1">MRPTSLHHTKPLFSGVAAASAGILLLSLTNQVHAEAAAADSSLASLDHLLDGLDTPPLNEGFTYLPDFHACPLPCSDFANVFSWVRYWSPDQLQRCDDPLLLQFSVEQPVASASASTSGAGVPLYACSLSSTSAANLTANPPPIDNPKTSNSLNKNRLSSALSCSAHSSSTLSPGGNTTALQKLTVATGASRSSGDGSDIAAMLQGLRSFFEAPDNCDETLVFARHRQTTVGMYMGANLGKTATADAVLKSLSDRLQSAGSASQPLTAQLCGGSGSRNRTAEHTLGIAMDATGDLSIVQQAVSAWSKGDCVSSLGSSLTPDASPVEAHVVDLAPVSGNTNSTLSVGRRYLPPLYRRSADTDAATPTPPAKNSDGTCASYVIQKTDTCSKLATQYGIKVTDLEKWNANKTWAWTDCAGMMYGNNICLSDGRAPLPPPQQGVECGPALPGTTLPKNASISMADLNPCPLNACCSNWGFCGVFPQHCDIHKPPGGGGPGAKDKNFQDTCISNCDRDIKQNSGPPATPMRVGYYEAFGMDRPCLNLKAKNANIGGVYTHIHWAFAAIDPTSLKPVINDTDKQWADFKGLQDVKRIVSFGGWSFSTDAATFEVMRKAILENRDTFAANVLKFVQDEGLDGVDFDWEYPAAPDIFAGGQPIGQKGDGLGYLKFLITMKQKLGKDKSLSIAAPASFWYLKPFPIDRIGDAIDYIVYMTYDLHGQWDYGNPNSFDSCPSGKCIRSHVNLTETKNSLSIITKAGVANNKVVVGEASYGRSFHMAQAGCWGPMCEFTGSRDKSDATPGRCTQTAGYISNAEINELIKQGAQSIYDGTSDTDIMLYNGDYVAYMTPTTKDRRRDAWKKLNFAGTVNWAVDLQAFTADDMDNASSDRGKAGSEGCIAGDDLTVDTGDLCEFTCDLGYCPESLCYCTERGILDPLPAVKNSSANDVVIAWNEQGIDINKMCKFACTYGYCPDDVCTTPLETMVDDDTDDTPPPPPPDDDPRAANANKCLIYENGDHDDSVAPCKIYCKPQLDAAAAAGRTSNYGCVGFWPLNQPIPWQTVSGLPCRVAGGTCNCDNYLVNEIANTVLEALPIIAEIGCYLLMSTLKLVVDIGSDIFTGGELSAGLNAVTTAAQIVNYVYPSDQDPQGAFDWWLSPCGNTDLVPDDIKKAFGILSDVTDAVTGFKGPKNIPKGSGRHGDDGNPKDQSKPRPTSNDPKPTDKPTGKPTDKPTGKPTGKPTGKPTDEPTACANPPKKVRRDGMGIGSVPQTTTHPNGAIETVWPRAEAGVMTADQYGEYENYDSEYYVDEVDSIDAAGAACKPKAKKCKIPKGKETQRLGAGKNTLRKLSCVNNVVKTQEMIVTSLVYAPAATKSQVAKKCEAAWTQACYHYSSVIRENPQYATLTCPQEAASTKHRQDAEATKVWSDQHKGKGWLDPQHRQWPKCDRDEYPPAYLLNDVDPAYVNSGHNRNGQLVRFVPGKQNQRAGQMWRGACFNGPVKELSNRDFQDKVARSPHTNVIHDTNLVQTEAAITVNQRPEFTISSWGPPPSADDGLSSNPCWPSAIAPNDPGFALLTYDKYYDTHPMPYNYLAAAPAPPAAPQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHI6</accession>
    <name>A0ABR3ZHI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_002919</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="66"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="161" mass="16245" checksum="5B6895FFB158F686" modified="2025-10-08" version="1">MSSSSFGTSSYSGTSTPTPTAVSSTASSSSSSPSSSFSPPSSSSSSSMPWTTSFSMSTIKSITTDFISTTTTTTSYNMDESTSACPVATSLPTCATACIHSAAIAIGCAQHYDMHHCQCVNFSALSNNAAPCIIGSCGLDKALEAKSVGVTICSACEGVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHS0</accession>
    <name>A0ABR3ZHS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor EF-1 gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TEF4</name>
        <name evidence="9" type="ORF">Sste5346_002569</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50040">
        <property type="entry name" value="EF1G_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="249"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="409" mass="45662" checksum="D9BBF0B8E33443AD" modified="2025-10-08" version="1">MSFGKLYGFLENPRTTGILAVAKANNLDIELVETVPATASADYKKINKLGKIPTFVGADGFTLSECIAIYVYVASQNEKTTLLGKTKQDYANILKWMSFFNAEVLPKFGDWYAPLLGRVPYNKKAVDDASKAALKALSVAEEHLLHNTFLVGERITVADIFGASIIARGLQLIFGKAWRAEFPNITRWFTTVYNQSIYSSVAPAAVFNDEPALTNVPPKKEAAPKKEAPKAAPKAAAAAEEEDAPAPKPKHPLEALPRATFALDEWKRQYSNSDTPAALKWFWENVKFDEYSIWKVEYKYNDELTMTFMSNNLIGGFNNRLEGSRKYLFGCASVYGVNNDSVIEGAFVIRGDDYLPVFDVAPDYESYSFTKLDPAKEEDRAYVDAQWSWEKPVTVNGKEYPHADGKVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIP8</accession>
    <name>A0ABR3ZIP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002254</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23160:SF19">
        <property type="entry name" value="MYOSIN HEAVY CHAIN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23160">
        <property type="entry name" value="SYNAPTONEMAL COMPLEX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="718"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="140"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="496"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="587"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="654"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="753"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="799" mass="85722" checksum="6D9B3D784D73880F" modified="2025-10-08" version="1">MADLPIALRRTRRSTSSLSTAFHGSPASAGMPTPPLTPSASSPSSAGSGPSTPSSRKTPSRRRVPQSRKRNTTSKRVRFSDPGQLAPSTPSTPTNCNCSSGLTPFIRRTSLQTGLPVSGDVSFLPLRQVLDGRVQRRLRRNGLSEEMNNAYAEKAEKTKRAKAAEEELARLRQEVAEKDDLISRLEGGDPDMTIMQDNDRVMALQREVNMLRRQLAAPTTDDPSTVEVDARTHNWTMAARDPFASTMSIDYGGGDYAGGDDDMTEAMTDVDDAADCGRPNTPDILDVDGNDLFGDATMAELQCSTPTRVRRYSSTTKTAGCGDSQMTVSFAQSSFPTPPATSPVAWADDADVGVVAPMTPSSTSPATPVTPSMHLFSTRRVAFSPVSSPPLPPPPPPPARMVDTEVQATLADPKTEELREQVTDLLRNLADKTAALEVLSKGLRGLSPQEESDTPVDASDIVARLASAFRTARLELEYLTPGEIELPLTAPAAAVLDLLLTRLRSLSQQVQQADAQVDEYHALEGDLRQQLGARVQAMDEMRAEGAAQAATIKEKEATITTHEATIASQSATISDLNIAADRFKGALASYARDVAELEALVGRLEADLKEKESVVERVTAEAADWKQTSDAVRKAARAAAATHGQALALRDARVHELRGEIEERDSALRAAQRRGHESARQLREDNAALQARLEAETQRATAAKAAVATLQVLLDGPTNSTDGEAASENNKKQKRLSLGRRIFGRRSGSLGVSSDGADATSASSTSSEGTSPSEPRSTKKRRRYDSGLGFLDEEEAETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJQ0</accession>
    <name>A0ABR3ZJQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein BIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046226412" description="Protein BIG1" evidence="2">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="28895" checksum="752E72DA864D6C30" modified="2025-10-08" version="1">MRSTTTLLSLLAAAASAPAVFAAPIPGSLSAEWERRLAAVASRTSLRLHTLSPEAAAALADETGPNAIVIDNRHYTPSGDIAPSAVLATPRPIVTTYLMDLGAAKPDAPKDAATAPVPIRIQNTHEGIEVVIIDADVEEALEAAKAIAGTPDSTPMISPVAVDPLEPAEHAALQHIDDAVPESVKMESQPAHHKSRPATDVPCHYAQLRRENDMMVIGLVAIFLLVIVAVELYDSSTEATAQDAPVGAIKLADDEISEKRPLSVQASPVTLASSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJZ3</accession>
    <name>A0ABR3ZJZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="53578" checksum="B9817E16D1FD1674" modified="2025-10-08" version="1">MEDPDIAWPAWKFGMKRDALFTTLHKQYNTFQSTIQDPDAFHHDVFEIASEASTTGEFHHLLAIRRDQRLRELNESLESASFEIIANPNLVGTTQWEFALQLFRTRSLDSLVRYFASYLPSSHPWHKPTSSGPVEAKCEQTVASTKPFFDDTIITHEPTMMSHSLSHTSLHHDLPPSPRSLTTYSDDMETSSHQLYCLNTLTPARTLSLDSYEGGRLHDDNNHTDDVIAVNDNEDDDEEFPSQFDDDTSQSSGPYTPVSMSDAEPDVAEDHEHHHHHNNPAVAYVATMQELVNAATPKPKTPPTTIAKNPIDTIKTITQHEAITNTTTPATNSLTTDVTIDTVESTATNTTSSPYRRPLQSGLVADTPRPASPLPVSMRVRHRSVSPSSRPWPVVHADTGRHHLATSSGITATRSSRQGRLHRLENLSSSSSSITRSASSCGRRRQGLGVEKTVLPRPMRTRLRERREAAASAAAEEQERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKB8</accession>
    <name>A0ABR3ZKB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NRPS-like protein biosynthetic cluster</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002357</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="46"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="569"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Thioester reductase (TE)" evidence="6">
        <location>
            <begin position="702"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1110" mass="120736" checksum="E7F50FEBBF12821E" modified="2025-10-08" version="1">MAPTPAERIEQFGKCYTIDDVVRLRARDEEQTPILGMPRGKDDPADYEYFTGAELDRMVDEACRILVTKGLVVNSKKTITLYAVSDLSFIVTFFALFRLGCKVLTMSARLGPPACLHLLKTAESDVVLHSSNARIDSTLAEVVVERPDIQLLPMLAREEFDKPDALAQPPFVREIADPEAEHVEVCLMAHSSGSTGLPKPLLLSHRSLQNSLLSGTGMRAFNALPWYHVHGLITSLQAMWMRRPAHLFNPLLPLTAANLVAALKFVKPEICHCVPYALSLIAEDQAGVDVLKECRIVTSAGAKTPDELGDRLIASGVNLGVIYGMTEVGHVGDSIYDRKPEDADSWAYVRPYPNLNMHMMFKHVEGNTYEAVFLQSHPALLMSNSNDPPGSYYAKDLFMPHPTIPNAWKYIARQDDRITLITGEKILPLGMEGAVREHPLVKDALMFGNDRAIPGMLVFRAQAAAALTEDEFIRAIWPSIEQANSIADEFARITRDMVASIAYGVEYPVTDKSNIIRAGATKLFSTQIEAIYARLDGGGDAGSGTNGTSNGTYSKKPASLDVAGLEAFIIDTFKTQTEIELPSADADFFASGVDSLRAIQARRLFQESLDFGSYRLPTNVVYDARNAANLAVVFYNLLNPNHATNGTNGTNGTNGVNGHTNGNGVHHETEQDPLAVMQSLVDKYSTFDTESQHADGGESVVLTGATGALGAHILHQLLYDSKVERVTCLVRGPHGLKRVHGSLRERGLDLGSSRTIARKLLVLEAPNLGDPLLGLDAFDYSGLVADTTTIIHAAWPVHFGLSASSFEPHIAGLRNLLQLSLQVPSRKPARILFASSISAAFNVPRPENGETAVVPEGPLASLSDASEGLGYAASKLIGERICEAAAREGANVAVLRIGQITGDTDRGIWNDREAVPLLVRSALELKALPRLDGQQGRCEWIPVDVVAAACIEIATAMKESGNITPRRNSADGPTRPSDVSDSPKARYYNINTPHIMSWNDEVLPAFKSAGLDFEAVSLEEWLGKLRARGEELMGDADAVAKRLPALKLAEYYERNYGGTPESANLRFDITKASRDSPTLAACPNMAEAQLAGKYLKAWLGKWESEINAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKC3</accession>
    <name>A0ABR3ZKC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF1">
        <property type="entry name" value="CONSERVED FUNGAL PROTEIN (AFU_ORTHOLOGUE AFUA_1G14230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045441582" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="28501" checksum="3D922D5720B49357" modified="2025-10-08" version="1">MHASSLLLASVAAVAVMASPTYPELTTENAMPGALDTVSSYFNLLAEKVQQTRQSAAAPVCDLSKAVFPANSATPALPPPSAGLVLKHVAIGRGTQNYTCDTTNATAVPVAVGALATLFNASCIAAAYPDVLDILPRVVLPFNLTDNEITAFATRLYPTNLAVSGHHFFETATTAFFNLDTPSGQIGQIPCAKNNTQSAPSNTVVGSDSDNRGQQGEAAVAWLKLLAKTGAGATGGLQEVYRLQTVGGSPPATCAGQPAAFTVQYAAQYWFYESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLJ9</accession>
    <name>A0ABR3ZLJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="73"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="549" mass="60725" checksum="2CFCDA99F8222C10" modified="2025-10-08" version="1">MDWQSIASKCQTAVIKAIPEKWHLPSPPDASVTDVTGIPRSCGLLTERQLELTEQTADALVKRLQAGELTSVELTEAFCARAAVAHQCVNCLTDYFYEEAMTRAAELDHFYKTTGKTVGPLHGLPVAIKDQLMMKDKAATFAAVAWHDNIADMDASLFRVLFNAGIVPFARTTMPQTGMMLQTVSNLWGRTVNPFHRGFSSGGSSGGDGALVGMHGSPFCPSTDIGGSIRAPATFNGLYAIRPSSERIPKGGLTTSAPGQVSIKVSCGPTCHSAVDLRLVTKILLQHYEYIGYDPTCVPFPWKENVFLPAKLCFGVLRDDGVVRPQPPIRRSLDETVHALKAAGHEVVEFAPPMDMWEVAQTTWKLYFQTGAKESRALVAAGNEPLTENFSFYTDLYEIKELTTPEVYALNTRQGAIRKQFNQAWMATRDKTGTGRPIDALLSPCAPSAGFPHEFPVWWGYFSMWNILDYPSTILPLNKFKIDPLTDPKDVRYTPRTNTPFDKMNHDIYDPDLWKNQPVCVQIVKQPYQDEDLLSVTEVVDDVINGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM90</accession>
    <name>A0ABR3ZM90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF5">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="523"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="399"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="879"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="321"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="447"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="998" mass="109604" checksum="918FC13DDA83E154" modified="2025-10-08" version="1">MSIHDSPGSLMGHDAIPSDDGSWNFLDHPGSGSQSDSPSVAFLPSPASRSLASYGVVAHMGQGLRGPSSSPGHHHSPEPLQMQLPPTSSPAQMGTGHQQARSSYSGPTAAQLAHTLSLQFANQGTDSINSGNSMDAGLNPTAFSESQFSAAAEQFLQFQDAMLFDQQLQDLSGFYSNAIPTATPAIQTPFISTQQQQQQFQQQQQLQEQLRQLQLQQQQQQRQNLFNPPNQHQSAADVPPWNATAVPEPQEASHIFVMDGPGLGSLSPESTTASLSAHASISQSASPRSPANIQMESEQPPQVQSQAQAAQWAAALQQFQLQQLQQMLQLQQAQVQQAQQAQQVQQAQELQQTTAAIALRQQRLQQLQQLQQLQQLQQLQQSEFPLITSPNLLSATQTSLQPTPVETKFTPVNPPASSKTTRPQQAQSKINKVRGSGTRVTKKKTASSSSSDKLQLSGSLDSSSGDDKFVIFTPKTISTHADSGSRFNPFECFEAMSATQKGRKGPLADEVKESALQVRRAGACFCCHSRKVKCDAQLPCKNCKKLATHLPHVICWRFDDFLGPLFPSLIREHFRKEVMAAFIAENIATFQDDVPHTVHLTAGRMFKSTLEIKNVRVFEAATTAIVLKHVHLTMGNDMVHLNAESSLPVALDLSENSVVGASLQQEKIKKTLRSYVDTIIKEEAYIDTVTGNLRHTELPKKILTIARNFYLKTSSPIVKQALQVYTMQYMMTHHLSFTEKSLHSLPLPSHYFTGSKFQTSRLLNRQVKSILDELMQEEVDALFRLFARELKPKARMAWATCLAAFLIFCLFMESTGLALDHYVITENQSNLDNHQPVNPAHARSEAVKLSRALENLPFRQFAYQFHNIYQTHQMAGNNSAAAGVSSSPTGSPPAAGAGTSAAPPSGSSIKAAFNPLFDNAPLDSGDLDKHATDFVLQLRALITGDSWNELDYLTFDSMIDSTIDAYPLPRDVSFNYTGRLCSKFLLSFEKPGYIFTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNJ3</accession>
    <name>A0ABR3ZNJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">CCA tRNA nucleotidyltransferase, mitochondrial</fullName>
            <ecNumber evidence="9">2.7.7.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CCA1</name>
        <name evidence="9" type="ORF">Sste5346_001247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:CCA tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="7">
        <location>
            <begin position="88"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="8">
        <location>
            <begin position="261"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="616" mass="68632" checksum="4FE174E9B8510CB4" modified="2025-10-08" version="1">MKRKLVDTDTGTDTVDQRASTSTLPPSLILSESTLKRRKQLAINMATPATTTIELTDQELRLKNFLLDVAATVDKDATDKGTEPLVLRWAGGWVRDKLLGIESHDIDTAINSMTGFNFAQQIKTFCDDPVNIGRHGMKERDLGNVHKVAANPDKSKHLETAMVRIFGMDIDFVNLRKETYTADSRNPQMEFGTAEEDAMRRDATVNALFYNLTTGLVEDFTGGLQDMADKRIQTPLEPLQTFTDDPLRVLRLVRFASRLQFTIDPAVEAVMADQQVLGALRQKISRERVGVEIEKMLKGQHPRDALALIDRLGLYNAIFTNVVGEQQDATATATAATPTEVPDLAGWPAVYEVLHTLAETKTPGSIYDTLVHTEEAEYLAWVIAAIVPWGQVAPPPTPPPPPPPVLTKGKNKGKPGNVSTKPPPPPIVATLRDGIRATNKFCDVVNGGYRHRDEILVLKQIVLDRKEPEMNERDRFGMAIRNWDNHGSNWRLQVLYALLWEVLVLAESTAPNRPAQEQIDSLLRGWQTFLEQIETLDLYDAPHIKRLLDGKQVAAALGIRPGPWMTTAMDICMAWQLRNPEETDPAGALEEVRQRKDEVGISSQLEKADKNKQEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNV4</accession>
    <name>A0ABR3ZNV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sm snRNP core protein Smd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smd1_2</name>
        <name evidence="3" type="ORF">Sste5346_001550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="208" mass="21554" checksum="89F7EB5E4E95C916" modified="2025-10-08" version="1">MASFFQELWESIFTPGPTPSLLIATNATFAVLQVVLFVLLIATYSIHFVILSVLAGGLWWAVNWFANELKVAKALQDEQDEEGKKKQRRRAAVAAATASPVSTDSETEVEGPEAPSGLATGKSTGRATRSGSARQRTVAAAAAQTEAETDGGAPALAAPAVAGAAIAGAAATLGSQDSNSASTSSQRLSSRSGVSTEDEWEKVSENEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP22</accession>
    <name>A0ABR3ZP22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001429</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF10">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045483598" description="mannan endo-1,4-beta-mannosidase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="50"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="426" mass="47387" checksum="BE7E36AA90B3A6C6" modified="2025-10-08" version="1">MRVLSTFTSLFGLAVSVRADGNTTQLGLIRKASDPQVPPTYPIGVPKEPFAKTAGQLFNINGTVGYFAGTNAWWLGHLTKNEDVDKAMQQIADTKYKIVRVWGFGDINSGFRPTADTADPLRVWFQQHPAPNDTEANQVALINYSPENGLPRLDYVVSTAERLGLKLVLPFVNNWADLGGMASYASAYGGADASVSFNFFENDRAQRVYRDYIRVLVERYRSSPAIFSWQLCNEPRCEGCDPAVIYNWAANISAYIKQPDMDPHHMVSLGDEGWFGANAGYREANNASSLAYESHGGVDFWGNLNISTLDYGTFHLYPSTWGYSFSWGNRWIEQHADAGNRAKKPVVLEEYGSPQRNDHSTVLLPWQQVVLNTSIAADQVWQFGPANLSFDVTKMGDEFSVYADAADFVTVSQKHAQAMLDKKVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPF8</accession>
    <name>A0ABR3ZPF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Suppressor of disruption of TFIIS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SDT1</name>
        <name evidence="1" type="ORF">Sste5346_001030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="257" mass="29108" checksum="54A4CD40A8075A1F" modified="2025-10-08" version="1">MGDAASLPGAAAASAEKTQKKVFFFDIDNCAKVHDRMAKLIDEYFVNHLSLPWDEAVRLHKEYYQNYGLAIEGLVRHHQIDPLEYNAKVDDALPLDEIIKPNPVLKQLLQDIDRDKVRLWLFTNAYVTHGKRVVRLLEVEDQFEGITFCDYGSTPLVCKPHKDMFAKAMREAGIERVEDCFFVGEYRPGIVPILAVINTTTDDSYINCKSARELGWTAAHLVEEGVTSPRTPASQFQISTLNELRTVYPQLFKSSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ37</accession>
    <name>A0ABR3ZQ37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="172" mass="18925" checksum="B205A01E4B801684" modified="2025-10-08" version="1">MSYHSTERRGRSSRRSADRYDDRYNDRYHYGHDTYYDDGYGYGRGDYTAVERYHSSRPVSSRRSKSSHRTSSSTHSGSSSHRSSSANRELKHVVTSALAAGAVEAFRLRKTPGPWASGAKGGRVATAAIGAAVADSAVERNNHNGKHSRRHVVEATVAGLLADRLLNGSRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ79</accession>
    <name>A0ABR3ZQ79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein smt3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="22386" checksum="17D10231708661C0" modified="2025-10-08" version="1">MAPKDRAADLDSSVGRLTIDSEKSNSGDTASKPAASKPKAPAAAPKKKKKQVVADSWEDEDVSSDDDDHDDDHDAKDVPASPPPTKTPPAGTTAPPPTPSTPSYHSSSSSNSTPFGGNTPLSANWNDTRASSGAGSSNDGPARRPEKTDAVARRLIAGALGIRAPRMTDEQRAYEKSLREAERKRREDSRAADKKQQEEADRAKKAIWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ96</accession>
    <name>A0ABR3ZQ96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exocyst complex component EXO84</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EXO84</name>
        <name evidence="10" type="ORF">Sste5346_001226</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Secretory vesicle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EXO84 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1220">
        <property type="entry name" value="Exo84p, C-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1210">
        <property type="entry name" value="Exo84p, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033961">
        <property type="entry name" value="Exo84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032403">
        <property type="entry name" value="Exo84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042561">
        <property type="entry name" value="Exo84_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042560">
        <property type="entry name" value="Exo84_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426:SF12">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16528">
        <property type="entry name" value="Exo84_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25345">
        <property type="entry name" value="PH_EXO84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst component Exo84 C-terminal" evidence="9">
        <location>
            <begin position="510"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="716"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="173"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="737" mass="81083" checksum="91BCCE6C3312D2AB" modified="2025-10-08" version="1">MSKALSSMSEDRLKISLRSGPKRNKNRPVISAPRQISGPVGPMTQNSLPMPRNDGGSRPAGGESQPLPRPQLSQQSGGKTSDYIKRRYSARFNDMPKNEFAPPVPSLPSFNQYESAARRPGAGGANMPIQRGDNRGGRGGSGGGGAGAPIPVDVKALRDPKLSADQYVASMLSDASEEDIVRYEEALRDLRSRAAADLQQNIYQNRAQFIKISKEAEKLKGEMRSLRNLMADLKANTTALRSASSTSMSNQSSSGGDGGRGGADASGLGAVGFSTGLSKRDKRSSVADRTALWNSQMQALYKNVEGSQRFLPMTLGRHVVQNAGQWIELDNATYKSRRAMQIFLLNDHLLVASRKKRKADGPNGGGGPLLKLVADRCWPLLDIEVIDMAGSGESVTSPSFGGSSGGPGSGRSKLTDAIMVRGVGQETVLYRTEKPDDPEKSALILNIRKVVEDLRRGIQSEMEANNKAKETINYFASRDPGLLQKTDLLETLSDIKDMLIEVDGKQQNLRWVESQMDELDIDIALQQFEPSVARVEKMQGLARGLKNNAVAQDFIEFKVEERSARLAALIIRDLIDTHNEQRKMRRNVSWLTRLGFEDRAREAYLEARSNMIQKRSRQCIFQGDLHLYIWELSFVYFSVIRNTVSCFQSCFPPAMMSACVKWAKEEVEAFNKILARQLSSTERGGEAWRQCMDQAHEHARMLSDVGLDFRNLVGHEPPTRTPAAPRVPSGPVGLGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQI9</accession>
    <name>A0ABR3ZQI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001493</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF63">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="47"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="59500" checksum="A4FF3F6C3346994E" modified="2025-10-08" version="1">MGVHLGAPTSTVAAPEKPQKGYFFFANREFPRATWYKRRNMRRLYIFIIVLIATNTANGFDGSMMNGLQTLSYWQNFFNHPQGSLLGLFNASMSLGSIVGQLPVPYIIDWYGRKVGLLVGCCIMILAIGLQSGAQNFGMFIAARLVLGFGNTIVMGSAPLLIAEIAHPQDRAILVTLSASSYQSGAFIASWVTYGTLQIKSDWSWRLPSLLQGICTIIILSTLYWIPESPRWLINRNRFDEARDILVKFHAEGDADDEFVQLEFSEIKIAIAMDKEANQTAWLDLVRTPGNRKRIGIITALAFFSQWSGNGLISYYLTYVMDAVGITNTQTQLGVNAGMNTLGLVVNIGLSFVADLFGRRPLYLASTIGTLVTFVPWTIISARDDISPNKGLAYGFILFTYLYTIAYGIKSGIITNYTTEILPYGLRAKGYTWLNFCICLALFFNQYINGIALDAIHWKYYIVYCVFITFEVWVIWAFVIETRYTPMEEIAKYFDGPDAVDIGEVAVAGVKESGIELAAPEIKTVPTAVVRSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQK8</accession>
    <name>A0ABR3ZQK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein NO VEIN C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052957">
        <property type="entry name" value="Auxin_embryo_med"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387:SF0">
        <property type="entry name" value="PROTEIN NO VEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387">
        <property type="entry name" value="WU:FJ29H11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1398" mass="156335" checksum="1966F8E170C472AD" modified="2025-10-08" version="1">MAGRAAARKVVERMGRQNGYIPPELLERMKEQFPDDYDKFVGPVESLKNLAAASVKTLAQNLYSSSAKFVFELLQNYDDNQYTSLSADRSPSVSFHIYSDRIIASCNEDGFTEANVTAICSVGQSSKKNGGHGSSGADGMGYTGEKGIGFKSVFMAAEDVHIQSGDYSFRFQYGKGDSGLGMTTPIWTDTDESLEDNESHITLTLRLKHYIMIKHVVPNLAPNDNRTDLDGTSRSDGVVVLGFPITAQSVPVLKNEYLFAFLPVKQMGFKFLIHADFVTQANREDIVTTSERNQGLADGIADAFIKAVLWFRDHQELQYTWMRYLPHDQEYPWGSFWQGVISNIRDRLAHPARPVYYPHVKTNNPNMDLDIPPMLDFDVIEASAVANSSWKHLFDKLGVKTASTAVVRDAIVTADYYISDQSPYGVGLLLPAEGGTLASDLPTPQSLSWKEWLYTFIGVRRHLRLVDKDGKSLSTICRYIAEHRPEKIEVLCRDGSKASLSSTYLPLDGLEKIARRFMADEFFPWLQLEVDINEFQTFPTEWLPLDEAFNLGHRCSPVTFLLDILQHIAKGNVDAASVNNPERIYSLYVRLQSEVGASASPEEELKLEKQIRDCFTSQKLIYLPARGTIEARWADPNGCVTESLVDFLHKASLFLICEKHFPKVYSRDGSSLKTFFAKTLDINPFSWSDVINEVIFLKEARADIDMLRSLYTSIQDRQKSNHKKDPVEAQKNYGRLRDKFTDNALILGFQNNNVAGSGGGDANWNTPAQCLWTTSETQIPGRLSLNNLYPDLYDFFVKGLGVETMTIKMVYDKLVGAPMTIEETKQTIRSFSAMLGGAKDDAPKKLDVTALLAKQIFPVRMPTNRGGGVKLCKGTDDFALVDRESLAEAFAGQAKLLNFDLETTRQLQPFLKWAGLRARGLSNLVEEISCVAGDDKQIISSRDRNIRYKARALLSIAHAFDSPRLGSSPEHLYCLILCADTYLTDRITSELRLQQDGQTIKVEQAAASFHFAESPNGLQIHVRRDEVSQEMCFNGTLAKRICKWLMTDQRKNICEEISSKMVQAVQAVLSSKKTAMKGILDLHGVRFLDVPDGQKADDFTDEEDEDVEGDEDDYEDEDVEGDEDDYEDDDTPNSEHDNTLDSIDVDAGEDLYITSMMARSSISGTRVAPLPENYVPGVFGSRVVSVAADTYATDYTDLLNLVVQAAQQASIPMYGATQRSAILENTDTSFRIRRWLQHAAALEKFQQIGAAGELFSTIRRYARGHASYADMPDWTGRETADITYADTDGVLTQLLIEKGYLSSEGWSGARPQYFIEVKATVSANIETPFFMSGGQYERMQNLSDNEGGGSHENVYMIVRVFGLGSGFVGYKILVDPEKMRRRGELAFTTPEKWSVVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQP2</accession>
    <name>A0ABR3ZQP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Long chronological lifespan protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LCL2</name>
        <name evidence="6" type="ORF">Sste5346_001380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LCL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23996">
        <property type="entry name" value="LCL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034543">
        <property type="entry name" value="LCL2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38425">
        <property type="entry name" value="LONG CHRONOLOGICAL LIFESPAN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38425:SF1">
        <property type="entry name" value="LONG CHRONOLOGICAL LIFESPAN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047365013" description="Long chronological lifespan protein 2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="122" mass="13508" checksum="A90133AFC7AD75CB" modified="2025-10-08" version="1">MTRTLFAWALALLYAHVAFAQFGFFDQMFGGGGGGGQHHNEPQNVPSDSAWYRGNVEKMHCDKYLCPDTLACVHFAHHCPCPFPSIEDKVELAEGHRLCVSRGGFKDGESARKIELARKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQR0</accession>
    <name>A0ABR3ZQR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF97">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="262"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="799" mass="85601" checksum="E4820C34A6962E15" modified="2025-10-08" version="1">MFSSLTETFMAPAGSKDAAAAGKAAGKTTGTGKETRPSPLRSNRTASKTDTRKSTSSSTSAAPTNSKQLPDKPTADPETQSDKFDTFGDVAGSDDNTPEIPRASVDMDELPIELIGLADSFIESLQAKVHPTPPNIDSLSQKFQDFYATASTHIATHIAALAMRQNRDRSPPPPITTRSSAASILRAKAASIGSKDKSGTPPPPPPKNESEQRMLSTEEISERKRARRALEQKKGLMEEAAERRLCEGIYDRIYRHRTTQDEAQDEKLRSKTAALDLVGISPADLGVDLGVPADASPEAVATRLKEVREWLEPARKQLVQMGQTHYPLGKLNRLKAAHKSIVDTLAHFHPSSSADEIMPMLIYTLITLPPEQLNVVSDLNFIQRFRWEQKMEGEAAYCLTNLEASISFLETVDLSTLRADEAPSGPVKTPSVETPKTETFPPAYFAQQGLTVPAAATPSAPEVNTGEVAITGIKPTPSPSAGLIAAVQLRNRRLSDLVNTPAHALSTASDAVMNTFNAADQGLKTIGNSLEGSYRLLFGRLGPQQQAASSSAADGATATADVVLPKTLDDARKLVTTPPSVSEDEASVNGDDQQHDKTPQTTPPPPKKTYRRISSLNMSTSVANKDKDKDNKDAKDAKDSKDDRMLSVLAGRKATSRDPSADSSRSSRKVLGDDDAASTTSAASNPALLDSVRNLGNSFNPMSRLSSIGNFRGFGRTASTPSAPLTTAAAEKPADGGDLATAFPDIAAALPPKPQVAPPIKRFMELHNPADLRISEVMELLRDYRRLATALKDLGAYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQT5</accession>
    <name>A0ABR3ZQT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="47685" checksum="8C6992EE5498C66A" modified="2025-10-08" version="1">MQGSSARPYGSDPHDRYSYPSYGRPEDQQYPQPAGHMAAAYPPPTHLQGPPAMSGYAPYLPPLPGPSSMQQGYPSSPRASAPAQIPSPVPGPPGSSDSVPPYASPKSQRKTKGHVAFIERGSASDANVYPPPLSISTRSLEPAVFLTTDLEMAKASNTFLDAIGRHTVKGLSLLDVISPMERERVISLQRQMHDERERKDPQYLPPIFVKRDEERVIQSLGLSADDLSRYAMDWHEYLTFSSADGQQRTFPVRMGLAKQDSIYFIVLLLHVAMRPFGGHPTPSPHSSYGYQPMQHAQPQHQIFSQPTPVSATFDVGRPRMPSDSGILPHRPTPSGGPSPMLSGLSPSISSAYGPSPGRSEYSTGPPSYQTPRSELVSGPLPHRQPQPAPGASFQLPPIRNRQDSTRQTETPATSRDDKSRVDIGGLIDSPEPPRRMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQX4</accession>
    <name>A0ABR3ZQX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283">
        <property type="entry name" value="EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283:SF5">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT LAGE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="107" mass="11463" checksum="B0CC9C33D7871E5B" modified="2025-10-08" version="1">MVVDPDFPCSLVIDIPFPTARLATVALQALSVDKELSPSVRRSFAVEDTPDDSSDSADSKTVLRTTYEASTNRMLRVSVNAFLDSVGLVVEVMGALDEDVLEAEAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR59</accession>
    <name>A0ABR3ZR59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl22</name>
        <name evidence="4" type="ORF">Sste5346_001109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="13919" checksum="BDBCB5AB438F2D3B" modified="2025-10-08" version="1">MAPQNKKSGKAAKTTKKFVINASQPASDKIFDVAAFEKYLTDRIKVDGRVGNLGETIAISQSGDGKIEIVAHNDLSGRYLKYLTKKFLKKMQLRDWLRVVSTSKGVYELKFFNVVNDDDAEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT17</accession>
    <name>A0ABR3ZT17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DYN2</name>
        <name evidence="11" type="ORF">Sste5346_000238</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="103" mass="11821" checksum="2CD7FA8E553C4A83" modified="2025-10-08" version="1">MSAEQHAAETTQLTREKLEAQVKSADMTDEMQTEAIEVAQEAMAKFTVEKDIAKHIKKTFDDRKGPTWHCIVGRNFGSFVTHETKHFVYFYLGHCAILLFKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT27</accession>
    <name>A0ABR3ZT27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphatidylinositol-3-phosphatase SAC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsd1</name>
        <name evidence="7" type="ORF">Sste5346_000038</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12283">
        <property type="entry name" value="RRM1_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12284">
        <property type="entry name" value="RRM2_RBM23_RBM39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="214"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="315"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="405"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="481"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="622" mass="68155" checksum="DAED33CF065A03CC" modified="2025-10-08" version="1">MASLDVEALLDAAATDKINGGTSTTANGDAPNGGAHTSNGHHSGRSSRSRSPRGDRERERDRADRERADRDRDRRRREPRSQSPRGSANGANGANGSSAIPNVHGADDRERTPARSEAGSHRSSRRRSRSPRRRRRNRGHGGGGGRSRSRSPNRYYRPRDSRRDRDDRYGGRSPRDRSRDRGGDRYGRDRSRDSRRGGGGRSASPPAIGERDRRTVFVQQLAARLRTRELKEFFEKAGPVAEAQIVKDRVSNRSKGVGYVEFKSEDTIAAALQLTGQKLLGIPVIVQVTEAEKNRQVRNTAETPSGGNATGVPFHRLYVGNIHFSITESDLRNVFEPFGELEFVQLQKDDSGRSRGYGFVQFRDSNQAREALEKMNGFDLAGRPIRVGLGNDKFTPESTAHLMQRFQGRDQPHNGNGRDSDRRGGDRSGGGSGNFDRAGARDNDKGSGAGALDDTDVAGVNFNNYSRDALMRKLARTDDAAVSSSSPATNGGGASDAVEQQRPIMKPRNDTKPLSVGVNVNLASRCVVLHNMFDPAEEEGDEWVKELEDDVRQEAEEKYGHVLHVALDANSGGDIYLKFDKVQGGENAIKGLNGRYFGGRMITAAPVVDAVYSSLFSRSKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTL5</accession>
    <name>A0ABR3ZTL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="348" mass="39451" checksum="F45F1D3513C10701" modified="2025-10-08" version="1">MFSFIETKWAKAFFLTVLLQAIICLAFEAYLFAEFESNVLQTKDNSQNNSFYRSIPTFLTLFIFAFLYELLLVWDALRMKNTIQVIGICIANLAFLIYTAIQTDQIDLAINSLSAIGAINPDIGSVALMDRVRPFLIAIPVIIGVTTIVMGFIAWKLYQEFAWDILKQIGADYRMKKRFLAYQIYIALLKFDFFFFLGFTVQFLVIVTGKTDVEFALTAAAIPITIAILLMAAFFTRHEIKVGMAISIVLYLCGLAWFFFKLVRIYEPGYKQNYTAVQKSLTAFAVLTILLIILTITNAFVCMHNFGSGLKAHILKRTDGEEKTAQYDQNSIGLNDMKAPLPSRMTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU47</accession>
    <name>A0ABR3ZU47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator of ribosomal biogenesis proteins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SFP1</name>
        <name evidence="8" type="ORF">Sste5346_000209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="736"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="797"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="607"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="865" mass="91410" checksum="A48B6B67F7BD2FA3" modified="2025-10-08" version="1">MKAAFKWLGAGTDDPANWVSTRATLTMDTKSQGKTAFSTAASTPSGASAAGACPRRGAPLAAATCSITPATATAALSSGTMRSHKPSSPSSPAPSSPSGSAVIPTGTTTAKVKRPSTPTSSRSSSPIPTPPSSTLQPSTIVRLDTSASRRLLSSSLARNSPPTKHRRLFADTHSRSGRYNETGDFSEGKRERPSVPTNKTKCPTTTSQTPQIAKPSDSTSSTSSSPKPIPKKRTFVGFDADLDKAIKEGNAIGTPSAFALDLDVDRRPSSRDNNSSSKNANMTSGHSFEAAMNRGRQDSFVSAGPKPISMINPNRGDAHRARRESLAGSLMGGGMSWGGLSVSSFIRDEMLGVSMGTSPNLAAHQSPSLHSTSYLPKMEANFMRDFMCCDRIWPTMHDLLQHYEESHTRQAPSTSRHAGGNALAIPGSQRNANGTSLGVPGQSNLQAIQQGQLSQAAGRPVGVPANANGSGLTMGLGVGGFQQMVRQQQLQQPVGGVGQQQQQAQQGQATPIAPKHQAIAINDDMDTVGDMEMDDAVGPMDMDDTSSSNQRTIQQTRQLFGQQRLQLNLNSGGLAHQALRTSTPTTPAAANFGFANNPTVSSVNTPTLSTQQGFPNQTQFSHESTPDLDDDEDVAGLGLKMDLGNMNLANNFGMGFANNLGGLDFSTINDPAKSLYSPNGAAGGDPPQLSQQQQALAQQLANFNLDQSQFPPGTDTAALLQQMSAAFLLPEEPKPFRCPVIGCEKAYKNQNGLKYHKAHGHATQQLHENGDGTFSIVNPETSAPYPGTMGMEKEKPFKCDYCGKRYKNLNGLKYHKQHSPACDPEVLAQQQNLLSTMAATLGQNPMGLNLGGIPTLPNIGEEPMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUC2</accession>
    <name>A0ABR3ZUC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_000288</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="144"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="536"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="582" mass="63065" checksum="74E6F0D2AC9E2D57" modified="2025-10-08" version="1">MPHATTTSTTVLRKPSPNNAPVPRRTLDAAAMGSQDEGLEKFPELDVHDTAGLDHGHNLNGKVNGTSTAQPSLPPVDQWRARKDSSVRWNAAATNSYSGGGGHGHSRQKSLGEALRTIRTRSGSTSQNVHEIADALKAPVSPMLIFLCILWYGSSALTNTSSKSILNAFEKPATLTIIQFAFVSIFCFLLSWLARVFPSMKRSMPALKHGIRYPDAETIRTTLPLAGFQIAGHLLSSTATTKIPVSLVHTIKGLSPLFTVFAYRIFLDIRYPTTTYLSLIPLTLGVALACSGSHSFSGGQLLGILYALVATGIFVTQNIVSKKLFNEASRAEAEGHGAQARKLDKLNLLCYSSGMAFVITGPIWLWSEGIGLLGDFLYDGSLDLSEGPNSFDHGRLFVEFVFNGFFHFAQNMLAFVLLSRVSPVTYSVASLIKRVFVITVAIVWFRSPTTWIQAVGIALTFLGLYFYDRTNQNKADRRARTMTNAKDGEPLLPLNAGPSANGIGLGLQNTGVIFENGSSSYAAGPHPYTEGYSASAREDYKKSDDFGREAVRGSSAGAANWMPPRTRQEDTWRVGDQVSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFY8</accession>
    <name>A0ABR3YFY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_010346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000134">
        <property type="protein sequence ID" value="KAL1887229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="151" mass="17141" checksum="B1619377262F737A" modified="2025-10-08" version="1">MPRLWSAAAGLISRISSPPPLPCPEPAYLDFSVIPDHLPTWLQTPSLIAAKIKHGNNISTSNPRSDGWDDFQNKAFWVQRCTIMMSFYCARLLILQKCIEHDRCAIVGMTNAPLPIQMKKIDMVLDFLRELEEIPFVYHQIKGEPSNEYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG00</accession>
    <name>A0ABR3YG00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000133">
        <property type="protein sequence ID" value="KAL1887241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF4">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="44"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="293" mass="32694" checksum="84997A2BE1875615" modified="2025-10-08" version="1">MSSQRQLPAASGTVEIVLLDGGGFRTTEDWRLHEGGHSRPFFLYDWCFFIQHKASGRKILWDLGISKDRSLYTPSVLANQWVGANPVGPRIPLTEQLKAIGHDPAEIDTVIFSHAHWDHCRPLRSEFPNASALFGPGTIPYCRPGHIQNLEPTMASQWDSRFFSDDENVRTESCSELDGHWAPWGPFDAAMDYFGDCSFWIIQAPGHMPGNLAACVRHPSGEHILLGSDCCHSRAIFDGRSQIAVSGPDSTKLCLHLDLDAALETIEKLREAVNSYGMHLALAHDPEFIREVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHF7</accession>
    <name>A0ABR3YHF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974:SF2">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="446" mass="49523" checksum="CE0C64E8D6DA2C43" modified="2025-10-08" version="1">MDTKDEKDSKLESTDAKMTPADEKTDIKSDEKTDLKDVKNEKNEKSAKADDDKIDADTNARILEAADERHRLVQQVTATQHAKPTLQQLAPQIADLKNKDYDAAQLFSTLKANLRERRDLLDKHQKHAESSLSKLFHRKGTDPKDLEIEEDAYFKAKAWADKAEVKMDRIDADLKALTAERDRLNALHEQNTAALVALDELYASVFDGPSPGLAEEDELENAVKNAQCVYDAIQARLTHAMTVAGHLNAARGKVTAALGFISAALTFSSQDVKNFNGIHHGSASSAAYLLTQGQPIFSSARADRKERANLARVPGLLAEAEHSLALAKEMDPEHLSKLVLLPKVEVAGQHHTLANVFDQIIDTPITDYFFHMEIEDTQDGVKECLAILDPEAAAAQMRADAIRQEREPAEAALNDGRKLLFDFRDELFKKALVGKWRPLRARATSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHP0</accession>
    <name>A0ABR3YHP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bactericidal permeability-increasing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="219"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="597"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="781"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="887" mass="98045" checksum="0473335DE422AC35" modified="2025-10-08" version="1">MASTGVNRPTNVRQRDEDIDRKLQLYGIVSAFQNGKMPSNDQIDATLNSFIASKALSSPSSRLSSEGRALVADFRDVVNQAKLLLLSKNNGNLLQDFIWKTSRHDYASIDVPGAPVSKDVAKQDGDRALEGLKTLGNLLITNGQFRKLLKDSSVLFRDILADSASKATSVVRPSDEALAQIDEPAPDDTWHDTPNLSKNDLKNRTKGLYKKNNQGDAGGASSVDAQRADELQGEATEAAQNKTAEYRDRAKAYLRSKVPQERRDQAVWRLKKMIIECQQHPEYQQAIQTLLDLAERYHGHAKTATANSSGVVQHTRGRLSEAEEDMKTLIERFANGTSTDNLWSSINEMYKLADNDQELHSWFSKVDSFLRRCLQEKGFVLEDASTEEWNRLYDHGNYLLREKYRPQTDNVADQVKFLADQFDKDAQNQAFAKSVNKLFYDLGNDENGKQTFKPHLVKDLTNVIIPAALESIAYIPIPRIEYSDSQVDAVIENLVLESDNFMPNVLEIYNDNYVSWGRKLGKVGKNRHSAQVNVSGIQMDLRNVSYYVKRKEGFPSLTDIGIFSVFLSGKGFSFKLGLSTAEPGNREHFFKVNKVDVDIDNLKITMHKSQHKLLFTVFKPILMRVMRPVLQKVLEKAIRDNFTEWDATLYAIKKDADRAAQELADQADAEDATNPNAYSRFFNAAKKRMDDTKERKKEEAKKKADKARKELDDKKLNIAYTKEDSIFPRINLPGGFSSKASHYRSMAREGDDWQSPVFTLGSAGTSKNIPKPPVVEKKEAPATNGNRVNGVNGAGRTNGATNGYHGTNGVNQANASGVSAAPLAVPVAVVAPAGSGALSSNAGSGYGDGIARTSGTVYDTPTALTGAAQDGVQRTTGVVSSVSGRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI63</accession>
    <name>A0ABR3YI63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="entry name" value="Alkyl sulfatase, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.30">
        <property type="entry name" value="Metallo-beta-lactamase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052195">
        <property type="entry name" value="Bact_Alkyl/Aryl-Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43223">
        <property type="entry name" value="ALKYL/ARYL-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43223:SF1">
        <property type="entry name" value="ALKYL_ARYL-SULFATASE BDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="84"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="854" mass="93662" checksum="E0BCE36006008BAA" modified="2025-10-08" version="1">MAEPSFEDTRDFRDADRGFIAALTPGVIKNDAGRVVWDIDAYDFMKGECPSTAHPHLWRQGQLNAKQGLFEVAPGIYQVRALDLSNMTIMEGKEGLLIIDPLISCECAAAGLALYREHRGKVDPSARTRRVTGMIYSHSHGDHYMGAGGVVTPEEIGSFPIIAPDGFIEAVMSESILAGPAMRRRGAMMYGNALPRGPTGQIGTGLGMGSSTGTTSLIPPDVLIKETGEELTVDGIRIVFQMVPGSEAPAEINFWFPDLRALCIPETATNCMHNIVTLRGAQVRDAKAWSGYLDEAIAMFGAGSDVMFGSHNWPTWTSDGLVTRLSEQRDLYGFLHDQTVRQMNLGKTGIEIAETMVLPPALSRAWHCRGFYGSLSHNVKGIYQKYMTWFDGNPAHLWQYPPKEEGARYVECFGGVEPLCTKAEEFMARGDHRFAVTLLAHATASLGEGKENPAVPLLADCFEKLGFGAENTTWRNFYLTASQRLRTGTASGMVAGGTTPLGPNLSVDQLLEILAVQLDGDRAGVREVPFAIDFAVTNATSTGAQAWRVLVSNGALTRRLLTASTSDKADLLMELTREQLLDVLRGKDVQVAKQEGNAAVLTELLDLVSETLSIIPHYQAIDTVPNPNSTDPMEVAVTQIKAERDTNLAAVKASLHEADTRRYSNDGKSAWWREEKMFASNAFSIQMNDFAYKALFPTASVKPNLVLSLDPKAMTIAFWARRDIRECEELTISYIEASNAGSFHARKALLHQRFGFACQCASCTNGHKTAIAVSDARRPSKLELALQRLLLTRDLYTEEGLCRQSTFRNEETGEVVADAFGPPSFNRQMGLALWRTESFVDALLYLRAAIAEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI71</accession>
    <name>A0ABR3YI71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">E3 SUMO-protein ligase pli1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pli1</name>
        <name evidence="12" type="ORF">Sste5346_009821</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16792">
        <property type="entry name" value="SP-RING_Siz-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031141">
        <property type="entry name" value="SIZ1/2_SP-RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PINIT" evidence="11">
        <location>
            <begin position="123"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="297"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="80"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="379"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="429"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="524"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="540"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="555" mass="59967" checksum="36C96E586DEFB64A" modified="2025-10-08" version="1">MASQQEEVNRMVATIQVLKNRDLISICQSNNLVKSGNKADLHKRIINYIDASVHDPNQRNYINMRNSILQVTNGSLAAANHRGGSYPIPSSPSSYNNTHQASNVSSPYNNGASGHNGAGSARSAIFSHQGLQFKPSPFYEIEMPLGDVRQCEAMAQHRNSITIVVRASQFPDLQRCLTDPNMRIMIFCAANNYGVQDIAFPYQCEIKVNTGEVKANLRGLKNKPGSTRPVDITDLIRLKPPTYGNSLEFTYALTNKRFYLALYLCKTFSATTLASRIERRSRITKDSVVREVTKQAQDPDIVATSLVLSLKCPLTYMRLSLPVRATTCKHIQCFDATSYLQLQEQGPQWLCPICSNPAPYDSLAVDEYVKDILENTSSELDQVTIDPDGTWHTGKDQGGGGGGTSTPPPASASASAATLLDDEFEILSTPVPSQRRNGYSNSQTNGNSNSNGVDLSSSNAATLINSRDTTATPNRSTATPIGGNGNGLNSNKKRPREVIDLTLDSDDEDDEPVQRRFKRQNTGSGYGSGTSGSGAGAGAGSSSALYDSALGNGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI86</accession>
    <name>A0ABR3YI86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1993 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="entry name" value="dinb family like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="BLL2446 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922:SF1">
        <property type="entry name" value="DUF1993 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="DinB/YfiT-like putative metalloenzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18616" checksum="82AF21CF31A832C2" modified="2025-10-08" version="1">MAPVTLYEVSITTFAKGLVTLKHILEKAAEHATAQGLGADAYVNASLCEDMRGLAFQIQVASNTAKKSVWRLTGTEVESWADDETTLAQLIARTQRTLDLVQAVDEASITGKDDNIVELQMGKAGTRNMPAKAYVLTYAVPNFFFHVQTAYAILRAQGVPLGKSDYLGGFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY6</accession>
    <name>A0ABR3YIY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009668</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="660"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="690"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="78762" checksum="6203A869FCD341B9" modified="2025-10-08" version="1">MGKYDPQVPVRPDQFPILCGPPYVQPDGSCTWDNIRELMEEVVVLEDIISLDDVLAMREMLRFVGPDLFWWHDDIGRGSPAMVNAARLGRIRILEVLLNYLDALTHEQRKDVKKDYDSEEKYVANTGNVWGTPLTAACLSAHVDVVRLLLARMPEVDINACDNYGYTPLQTVARHARRTIPSADRDRYGVSPAEVAAMDEESERRVEIVRLLLAHSAKKEAPDKSFTRVGQTAKEAFDACEGTWAEDGYPDLRVLVDRPRGIGNVLIQALVRPTGSDIRLTRMLIDDAGMDIHEGYFSPTATFDGRGENGVADDVDDEETKLFIEAKSKETASALDVGREAAFAINVASMGAISAAEKRVYGPGQGPDTYLTPLAAAALCRNAAGVAALLETPGADFYSDLVAPCIPADLGALDVETAAVLAETTAMRPLHAAMIGRVNEHVRVPYFREPEFHRKFVLRQEAYGVDSRNKIRTRNRLLGESDEPLEHPVDPDTIRVTFDCNITSGAARKAYLDDCVATVQMLTADPAVRAATINAMHPHEGMQYTPLQLGARFDRLPMLRVLLDAGADPRPPVPHTGHSVFFSVFASLLQLCSKTGCCSWHDDRMQHILYHLEVIAIDASIGTAGMTSLLRDLLWLDTGDEKDEKDEAIRLARINEADADGNTALHWAMGYDLQHAQTALLALGARPDARNAAGEVPAQGTPPTTTRRNERPRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK04</accession>
    <name>A0ABR3YK04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="62695" checksum="9A06147550D6D481" modified="2025-10-08" version="1">MQGIAGQLLAFLVDHWAPVLAVTFLAYLAKNRYGYGINKYPGPFLASLTDWWRFWDVYKRRPERTQRRLHDKHGPVVRLGPNTLTFSDPKALKTIYGLNKGFIKSDFYLPQQSVVNGHRLASLFSTVDNDFHAQFRRCVNGAFAMSQLVQYEPFVDNTTKLFLKQTEKLYVNNPEGCDFTRWLQFYAFDVIGEITYTKRHGFIEKNEDIDGIVAYLSWLFLYVAPIGQIPFLDLLFLKNPIYLKLSQWGLIDSTFPVAKFARARMAERLPDIAEGKGPILPTKAEKRPAADLLSKFMAAKEARPEFMTDTLVQTMAVSMAFAGSETTAISLSAVFYFLLRNPAALKSLYEELDNAARDGLFSDYETGLVTWHESQKLPYLDACVKEAFRLHPAAGLPMERIVPAGGTEIAGRFIPGGTIVGCSAWVLHHNKDVFGEDTDAFRPERWLVDEAKVAAAKKGQAQTEEREREEQRIKEMNGMMLQFGMGSRTCIGKNISLLEIYKVVPSLLRRFEIDFVDPKQEWKLINAWFVKQINFWTKFKVRELVQPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKD5</accession>
    <name>A0ABR3YKD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Co-chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AHA1</name>
        <name evidence="4" type="ORF">Sste5346_009425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08892">
        <property type="entry name" value="SRPBCC_Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="ASHA1/2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="327" mass="36359" checksum="4D00824F714D4E13" modified="2025-10-08" version="1">MVLHNPNNWHWVNKDAAPWAKQWFEDNLTKLSAEQGDVNARISKVISSEGDVDVSQRKGKVITIYDVKLVLEYTGAAPDEDDVSGSITIPEVAHDTEEDEFVFEIDIYSDSKGKQPVKDLVRSQLVPQLRKTLIKLAGALVAEHGKDIQHAPGSNPSSGFTTPKYHPPTGAAAKDASSATTSQTTGGHTVNTTTVTDQEEFRTTAEQLYQTFTDPQRIAAFTRAQPKLFEGAKVGGKFELFDGNVSGAYKELKEPTHIVQSWRLKQWPAGHYSTLRIDFDQNDVDSVTVMRVEWSGVPVGQEEVTKRNWSEYYVRSIKLTFGFGTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKN7</accession>
    <name>A0ABR3YKN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF2">
        <property type="entry name" value="DUF1446 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11420)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="518"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="69267" checksum="0CC76A140949D86F" modified="2025-10-08" version="1">MPSAKRGIRIAGCSGGFTDRQRAIGDIAKNCDVDCIIGDWLSECTMTLHGAQKIENEKLKAEGRLPENVEGLYDPSFMENLEPALPYLKSKNIKLAVNAGASDTELLAQVVLAEVKKQGLDLKVAWVAGDDVTDTVKRLYNDGKGEDFVGLMTRKPLREWGHDIVCAQCYLGGAGVAEALRQGADIVICGRVADAATTVGAAMWWHGWDREADLDPLAGSLIAGHLIECSSYVCGGYYSGFKNLMESCENIGFPIAEILQDGTSIITKEANTDGEISVGTVESQLLYEIQGPLYYGSDVTAHIEGIKMTQLEKDKVLVTGVKGLPAPSTTKVGITAFGGYQAEFHIFICGLDLEAKAEWTERQIRHSIGKNIDEFSCLSFQLNGYSMDNPRSIESSTVDFRIFAQTKNRKLMDKTSVDVPGLNRWCLENFLQSCPGATLGNDMRQSEGKPFYEYFVTLLQQKEVKHQARLLWSDSTIDIPVQKNVRTDYPRDQNSYETTNPVPLDSFGPTTRGPLGWIVGCRSGDKASDANVGFYVRHDDEWDWLRSVLTIDKIKQLLEKSDKGKKIERFELPGIRAVHFLLLDHLDRGYNSTSELDYLGKNLGEYLRAKHIDLPNKFLNRGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKN8</accession>
    <name>A0ABR3YKN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxypeptidase Y-deficient</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PEP7</name>
        <name evidence="3" type="ORF">Sste5346_009279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.20">
        <property type="entry name" value="Rabenosyn, Rab binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021565">
        <property type="entry name" value="Rbsn_Rab-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11464">
        <property type="entry name" value="Rbsn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rabenosyn Rab binding" evidence="2">
        <location>
            <begin position="217"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="201"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="278" mass="31543" checksum="546440F95EF183C7" modified="2025-10-08" version="1">MYQTKLSRSANYDPVRGYWARVCETCYKSRPGYNDHHAHKPADQRAYETLRQFEWGIRQMMPLFQRSLQSLQPDAPGSNRPPATRAQIQEAAKIRKRLMGSFTKYNLAAVRLRDLKTDSPAQQRLQKSVYSAASTFLHANMVPLKHVPKMLQSQQPSGSPFTHRRLLANLNGSSSNMSPLRNGENITDSGSVACSEASTAVSLLETEERELREKLVVLEEQRFLVQQMVDSARGSRRFEEVGALTRNVEELDNEINRVKQQVSGVEDRWEGVYAAGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKV1</accession>
    <name>A0ABR3YKV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PET9</name>
        <name evidence="17" type="ORF">Sste5346_009238</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="13"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="118"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="218"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1888970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="315" mass="34234" checksum="255CE9FA3BFC4958" modified="2025-10-08" version="1">MTSKEDIKIWGMPSFVVDFLMGGVSAAVSKTAAAPIERVKLLVQNQDEMIKAGRLDRRYDGIADCFRRTIADEGVMSLWRGNTANVIRYFPTQALNFAFRDKFKKMFGYKKDRDGYWMWMAGNLASGGAAGATSLMFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTLASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDSIKPVVLVGNLSNNFLASFALGWCVTTGAGIASYPLDTVRRRMMMTSGEAVKYSSSLDAFRQIVAKEGVKSLFKGAGANILRGVAGAGVLSIYDQLQVIVFGKAFKGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKZ8</accession>
    <name>A0ABR3YKZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">rRNA-processing protein utp21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UTP21</name>
        <name evidence="5" type="ORF">Sste5346_009348</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059157">
        <property type="entry name" value="WDR36-Utp21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25171">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR36/Utp21 N-terminal" evidence="4">
        <location>
            <begin position="66"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="698"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="3">
        <location>
            <begin position="944"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="889"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1007"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1177" mass="125605" checksum="CDD1D6ABE000972C" modified="2025-10-08" version="1">MPHSESGAPLVKRQKLATAPASSSKDQSSAIATGSNIFAPFRTVGLVSPTAVPFTSIPLGKTTFQITTSAGRCLQTYDLKRGLNLVFVTRPQTPRDITATYAWKHKVYAAWGGKQEGEQQDDEEDDEESSNDGYDSDSDSDSDAPPNTTQGVWVFQRGRKVGELPMPRDLTEPIRQITIFGAWIVGLARTRIEVWKSTTLEHYTTLNPTATTPGGNVLTGGMCTMPTFLNKLFVGRADGWVEIWNVSSGKLVYTILPPKTANPPGGVTCLEPTPALGLLAIAYSAGPLVIHDVLRDQPLIHVEAGTAGVTADGENDAPVTSISFRTDGKGAGQDGRLEGVMATATTASGDVTFWDLNKGGRIMGVLRSAHNPPSVGSGGVRGGISKIEFLVGQPVILTSGLDNSLRSWIFDETPFSPIPRTLHTRSGHAAPVNCLEFLPSDFDGADSGNKWLLSGGLDRSLWGWSLRRDGQSSELSQGNVRQKAKKMGILSTSALRHGPTTTLEDLKAPPITCIASSLNRDGGMGALPGKMPIWLKIGGPHGNGGHKNKAGRTGDGLRPGDTESSSMTGWESVVTAHREDAYARTWFWGRKRAGRWSLCTGDNKHVSTVAISPCGTFALVGSVGGSIDMYNLQSGIHRQRFPSRLTPAQARALKVQQQLRQADGVTQLQATATSGDGSGSDAASVLGGKFAGFRSPGAGRHTDAVTGVVIDNLNSVVVSCSLDGTVKFWDFLTGHLVDQINEWGGVPVTACRYHAANDLLAFACGDNTIRVVDLVTRKTIRVFRAGLPGQTHTPSNINDLCFSSDGRWIVAVTQDDARLRVWDLPTSHLIDSVPLDRPGRAVAFSGTGEYLAVAPDGALGVHLWTNKTLFKHVPTRPVVEAPTADRKALPALGSTSKKGRKKTVVAGPTVSGEGGAGLLEGAFADEGADGEGEGDDIVPAKILDQLSADMTTLSLVPKARWQTLLHLDLIKQRNRPREAPKVPEKAPFFLGTVGSAEAEKAGLGAAYTNGQNADQDNSKDGKDAGSNDARSRILTLDLTRAQQALTVKLHQGKTGDFAPFVDHLKSLPPAQADLELRSLAADEGELALFVRAMTSRLRARRDYELVQAWMTVFLRLHGSTAVEANVGGDDDDDTSDLDDFAAALAEWRVVQEQERSRLDALVGYCGGVVGFLRNPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLD3</accession>
    <name>A0ABR3YLD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="1">
        <location>
            <begin position="24"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="439" mass="46547" checksum="D88BEECA5F2E07A6" modified="2025-10-08" version="1">MADPGPTLPSICPSILTPSYSAPIVAPGWTAQLVVTGLLTPRSLLFDDAGALLVVESGTGIQRITFDDYGDTCLVVRNSNQVVDQPDLNHSLEFSAETGTLYASSSNNVYAWDYDSSTGTASLTPPQTLVTGMDGTDHVSRTLLLSRDDPGKLIVSRGSYSNNDQAAVFLLSGHSQIRAFDITSPAAGNFPYSFTSGNPIGFGLRNSVGIAEEPTTNALYSVENSIDDIVRNGVDVHDNNPGEELNYHGPISQIPSSPSPNFGYPSCFALWDPTNFPDLGTLTVGEQFSMTQSTSLNDQICASSYVAPRLTFQAHQAPLDIIFTPSGSAAYVSFHGSWDRSQPVGYKVSEIAFSGGQPVAASDSTTSTNDILSNADLSVCPGQCFRPVGLAMDSKGRIFVSSDTTGEIYVLQKTPATTGGGSACRPNKARKRRGVYVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLL7</accession>
    <name>A0ABR3YLL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000086">
        <property type="protein sequence ID" value="KAL1888733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="20091" checksum="6D1A61291E8F1611" modified="2025-10-08" version="1">MPLPAPTITTTEQPAATGSCFGDTHLDYCGVEGGSLCICDSVIQEPTSYIAQAGQCSQGCVGNSNVQCGGDTYANAYAAVNIAENGTQPAAYTPASLDRYSYLGCVSDSTKRLLTRRPSSASPSWTCRTAVPCTGNRAQACCGYYRLGLCKATGPNTASATQSLVSSANTANTVPPTKSALNTPSSTASTPPALHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLM9</accession>
    <name>A0ABR3YLM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="866" mass="96394" checksum="952FD30EE0E13008" modified="2025-10-08" version="1">MDALLAYSPAPITRLPNELIWSILQLLDLDDAFGLGRTCRFFRDIMRDNSICRMLVELTAKKQFPFSDECIRMRPAYKYAAALRAVAKRHQAIANLQPFAVAVVAEADVPIYGGRNGSVGGSGIGNGPTSPGNGGYSRGSYDPPPSAPPFVYAGQTLLYMSGRTLRILPLHGGVHKETTINVRQLLNDVVPASQDKRNFHFRPLHYSDGIVSCVYVHRVPSTGHQESWLILFNPTTNWRRSHRLALPHHRLFVRNNKEYLVFGTYTSRRLPEQDTDGEGLGGGGGSNTPTMTPIGHRRWVLRHYSILEEKWSTKAIFLDNSIGLADLGSSLCFEVLDGYFYALANQQRYLDEENNDVDHYDGLEEEEYDSEGDDMSIRSGTGEHSSNSSSTLSGRATGLFAPASYYTCERFPLSDPQQRQTPTRASLWRRRNNEGAVDDRWTTLRLEKSETTGQIMAVESRKEWLRVSGASSSRRTYYMQPLKFKGANRAAKQRRRSTANAFRLPEHVHPGDDAARMMPLTLSRCGARVYSMASQTFMDLYYQNPPASADPLAAPRLVLRAGTRRSRLSSDKKSEEGDSNPKDDNNDKGGDSLLYPLREINKHYVDNEVVTWPMEKSENGTANSSSNDNDSHSHSQAEALGDVLNPPGYCGTITATSWDDRVLIYATTSSDESDNGGRQAIVVVSFDPTLCLPGLEVWGKDKKGEEDKEEQGGSETEDEIEDEGLGYSEGALPLPAFSPSRKRKLSDLLEKDGEEEGEEHEDEGRRQRGRRGSSQASDIQAYDFQAIDFNSQATSIDEGRRGKGKETGTESILLSPPASSPIDMDEKTAAKPSWVTLVKPMYRAIGRGFDFSYHKRNRTGDYLGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMR1</accession>
    <name>A0ABR3YMR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Erg26, C-3 sterol dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.170</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ERG26_2</name>
        <name evidence="2" type="ORF">Sste5346_008760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.170" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000252">
        <property type="term" value="F:3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="369" mass="39853" checksum="A277615C0C2C6B37" modified="2025-10-08" version="1">MSTGGSLVIGGCGFLGYHVVRHLLQDGNESLQPVHIFDLNTSNNRVDGVASYTQGAVSDGAAVKTLLDKLQPRVVFHMASPPASLPSHRKSKFHATNVVGTATLLSAAAESPSVRAFVYTSTVDVYADPPHNDSTENQPLWTDVYSGEGRRPPKMSEYCYTKTVADGLVRAANSDQLKTVVLRPGHVYGERHTQGLYEMLEAAKGPLVQLGSGKGKKETVLMEVASADNVAAGHVLAAKALLGDSSEGVAGEAFNLSDGSPVPFWHHVRVIWGVAKGKEALDKIWVLPPWLMIGVVFIAEWSFWALSLGTREPPTELTSASLSYCIESHSYSIDKARRLLCFAPVANHDEVLAESVRWELNRRGQPVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPM3</accession>
    <name>A0ABR3YPM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="609"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="736" mass="82230" checksum="B2D8CE965269358F" modified="2025-10-08" version="1">MSAQTATPAQSPTTAGSSSKRCSMACTTCRQVKLRCDAAQRYPSPCSRCEKRRKTCVFDSEFKRRPVRGALERLLEEKEQLKQIVDSLGAGATVTTNAGTAPTTSHITPSQTQSEASPVVHTVDDTPGYDLDGVRLGFAVVDDLFEFYTSVFLPMLPILDITSKSPAAVCADSELLFWTILITAAQNHPEHRISVFVPLVTPYRRLLADALVRPARTVYMTQALLIVTAWPLSVEMQRNDPSWYYCGFAASSAIHLRLHEAEALWWYSSAGGREEVVAEGGDGHRGNSARYRTWLGAFVVSNTLSIDMGLPSPMGAVAPLAQNLLKQLGDDALPEVFAARIELQSILFRSDTILKDTASSSASFSSRNPLLDVLERELDSFEQKWTTVESTSERKKLPLTIHLDLLGARLRLRAPLLMPRSRPGPTETTSHMEPDIFAEAAWQKTVHYAGQIVQLMADYLLGGNEVDNTLTEDKRNGQPRHIIAAEKRCLPKHYYRVLLMAVFALLIYVMLHQKRRAEGSQDEVFTRALAYTRQAPDLIQALSRHPADEHGRCARFLRLVAHYVDDPSLANDFADDFARALAPPVNDIIEVGIKASWVIRQRVRQKYLEGPDRDLPRRQPAASTPSTTAARRTRVTRSSTAARFAHDPMPPTQETREEIMNEYNAVEMTQAQPLRQTPVYPEDAGQPFGYQVDNNRVPPAQDNLGLSDELFTDWNAWFDDADDFMSLFRAPTWNPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPW7</accession>
    <name>A0ABR3YPW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translocation protein S66</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sec66</name>
        <name evidence="3" type="ORF">Sste5346_008236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018624">
        <property type="entry name" value="Sec66"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229:SF1">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09802">
        <property type="entry name" value="Sec66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="28621" checksum="BBD52FB4D9BEC0FE" modified="2025-10-08" version="1">MVSLSVDWQGLILPVAYLLVLGGTFAAFSTIYRRRKAVQSANLSPWFPPHLQRNVYLSLLHMEPEAGSSSEKPTKVPDPILRAALLRRAVEDIHRIIQIRTGKQACQSLLQRGSVGDDLWQRFLRAEKEMEDELRDVVMEANALVPNWGQIIFQTANAIAANEMLRTKLDAVQDKAAAEKAWWEKRKATLGEVATTSAPVTEEKTAPSSPTATSKTSEDDTVLVDTPAAAPAAAPAAAAADAARPSTPAATTSTPSGKKKKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ23</accession>
    <name>A0ABR3YQ23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Multicopper oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13880">
        <property type="entry name" value="CuRO_2_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF502">
        <property type="entry name" value="MULTICOPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046503000" description="Multicopper oxidase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="79"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="204"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="431"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="63683" checksum="B3D3FBDBD89A5E06" modified="2025-10-08" version="1">MHFSRVVASAVWAATASAFPHFWTTRDSPSEVAARDAALSKRCTNSADDRACWGDYDISTNYYDTSPDTGVTREFWWDITNTTAAPDGIERIILAINGTVPGPTIYADWGDTVVVHVTNSLANNGSSIHFHGIRQNYTNQNDGVPSLTQCPIAPGESYTYTWKATQYGSSWYHSHYYVQAWDGVFGGIQINGPATANYDEDLGVLILNDWMHETADVEILSAEAHGPPTLNGGLLNGTNTYTDSTTGTTTGSRFQTTFVAGQRYRLRLVNAAADTQFRFSIDNHTLSVIAADFVPIVPYTAESVSISMGQRYDVVVTANATTTESVTDFWMRAIMVQSCSDNDSPNNVLGIVRYDSSSTSDPTSTAWSSATDDGTVACADEPMASLVPYLAVAATDDPTNTTTFAVDLYTSNGIGLWEMGATSFVSQWDYPTLLQVSEGNDTWGTAQNVYQYPDANTWAYMVIQTTNQQPHPMHLHGHDFWVIGQGTGTYDATTTELTLTNAPRRDVVLLPGDGFVVIAFYTDNPGAWLMHCHIAWHTTEGLAIQLLERESEIPALLDTALNTTCAAWDTYTAADAIVQDDSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQE0</accession>
    <name>A0ABR3YQE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="42970" checksum="D3E8B0643660F9B6" modified="2025-10-08" version="1">MSNANDARALREAQLSPNAAAAAAPANAETSNNETVMITSNDGETFYAGRGLAGHFHHQSNEHEDHSNIAAAAAAFPTAKATSWTDEDAYAAYRGNSNTATANDTNIAYSPYGTNLNGTQEPDAHLPANDDTSHGNSTGDDAPTYVAPADFSTAFYGPMGLDSEVTTDEDAAQQATSHMYSSTNFYGQDELQDRMTNDNNNDDADAGHYCGHDELADNFTADAMPSTYLAPPNFTGSFYGSDELEQASSTDFFSGYNQDHRADLWSDQPAPPSYETVEPHSEPTATPSFNPSVPIKSGETLLEIKLEPLPARHFESHEAEEAIHEDPARSSTSTKPKPKRTAKNELMLNAVRTRRRQTKSAMGARAAAEKATKKAAEQVADQAVDQTDDQATSAAAAADPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQL9</accession>
    <name>A0ABR3YQL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">DNA repair protein rad50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RAD50</name>
        <name evidence="17" type="ORF">Sste5346_008162</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004584">
        <property type="entry name" value="Rad50_eukaryotes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00606">
        <property type="entry name" value="rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="16">
        <location>
            <begin position="20"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="338"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="211"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="486"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="603"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="662"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="736"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="870"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1011"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="361"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1890646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1336" mass="153114" checksum="C256569797724161" modified="2025-10-08" version="1">MYPPRQLLTYTFRTTAKIEKLGIRGIRSFSPASQESMLFNTPLTLIVGYNGSGKTTIIETLKYATTGEQPPNSKGGAFIHDPKLCGEKEVLAQVRLSFQSTVGQKLVVTRSLQLTMKKTQRSMKTLDGSLVIYNNGERTGLSTKVGELDELVPNYLGVSPAILDAVIFCHQDESLWPMSEPAALKKKFDEIFEAMKYTKAIDNLKVVRKKQGEELQKLKMLEATNKEAKEKGQRAEKHLASLQTQIEDLREQGEDLTRQMDDVQLSAKERREQATSFFGIVQELKSKQDQFEVRSETIAELKESIVKMRIESDDWLDEHLQQYEETLARLQNDKEEKTAQFRKLQSGLTTSRNALGAKQAEQGKHQSDKEKYERQLQTRIEMIHEAAVRHEIRGYESDDLRDSHIRAFRERIQKVLQDKRRDLERLQRENAKELEKDTAVISGLETQKATRTQDRVSAKQRIAAIDKRMAVLQRDIQKLDVDEGAQAILESTFADLESRLKKATEEVQAAGIDGQIEQENNHIWQLENESEKLSREMVECMRRASDRAQLDLRRKEAVERKRRLDTLTSTWRDKLAAIVGQGWTAESVDADFQSALQGLVTTASAARKQVESSQQELKQVEYKLSTIRDRQKKTVAQSAKCECDVLEVLRAVKAGGEEGSASASDSVSIEEYQEELDNLESEILTAEKDISLFDHLKDYYSKSQKVLNRFNKCSHCDRSFADQPRERSKLMEKIAKNLDDKQKKELEQEKDMLEQNLGQLRAVRTQYETYTRLKSELPGLRDELKQVETQRDTLVRRLEDQDAAFKEADEKRMDVESMGKTVTSISQAVKDVAESDEQIEKLASQQQQLAGSSRSSEEIQELQATCADQLRAAKQRLTKLSDDRQRMRDAVSTLELERSELKNKIAHAARQVERKADLVSQVQAFKEESTQQREVIQQTDRDLEALEPEIAKARTIRQDTLQRGQEKERQGAQERDAVAHTVSELRMVEKDIEDYIDRGGPALLVANARTIETLEQAITGQEHEADELAAQVNKMKAEIDNSDREKKNISDNLSYRRNSRLLDDLRRDILDLESRNAEDDYERLVGEAKRFEVQHSKLLAERSAIWGSMKTKDEELLRLLDEYEQEYKEAEFRYRESHIRVETTKAAIDDLGRYSAALDKAIMEYHGLKMEEVNRIAGELWRATYQGTDIDTILIRSDNETATGKRNYNYRVCMVKQDTEMDMRGRCSAGQKVLASIIIRLALAESFGVNCGLIALDEPTTNLDSDNIRSLAVALHAIIKARQAQANFQLIVITHDEEFLRHMRCSDFCYTFYRVSRDDRQNSVVTREPITRLMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV0</accession>
    <name>A0ABR3YQV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="533"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="40"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="586" mass="61874" checksum="E6A210813F9BDE32" modified="2025-10-08" version="1">MAASDIDAAAKAADVEYDEYRQQPAAVAALGDIDEVPKNYYYSPRFIGTGFAIGINLLASTGGFAMIAPILGEIDASIGPGSIIWLSLVYTMMLAVGLTLVGQMSDVFGRRYFFIGGTLLGAVGATIASRAQTIPVAIGGEVLVGLSAATGYSYAFVIGELVPMKWRFLANAIIFWGSMPTAGFGSAISTAFVLYTEQGWRWAYYLLIIANVTAAALYSLFYFPPSFHQKHGADTIMRWVKNYDYIGMFLYVAGLLLFILGLSWGGSIYPWKSAGVIAPVIIGFFCLVGLMVYEAKAKIAEPLVPIHLFKNRGFLASAIVLSLGASVYYSQAIVWPSMAANVYSNGRAMWAGWAGTLVGIGITAGEIIGGTLAKHIGFFKYQLLVLITISTISLGAMTTCTPDTPKTAMGLVFLATTAVGWAEAIVLPACNICIEDQNEIGTATGIAGSMRSAISTVASTIYSVVLASRETTTLSTVVPKALTKAGLSAPSIEAYMAAVAAGETATDLGKISGVTADIIAIGSRAYQVAYADAYRTIFFTSIAFGVLALICATFVPNFDALLTDKVATQLNLSGKEVTTPANDEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR42</accession>
    <name>A0ABR3YR42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630:SF6">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="40799" checksum="5A8C68859C2424AA" modified="2025-10-08" version="1">MATAVITNTAPAALPAEAKRSTNDYLQNSHGTVHDYDTKVGGTHDILASQANQNIPFGDWRDDFFSKGYVVIKGAIPRERADQYRATAMDWFNKFPFGFDMNDKSTWVQEKLPMMMKGGMILNYCAAHEKWVWDARCEDGVIDAFAKLWGTHELLVSFDAVNVTLPGRTDVQWSPWPHVDQSPTRRGLACAQGIINFSNAGPKDGGLVLLQGSSELFERFFQEHPPAPKAAGAPGQFDWYGFKEEDVQWFISQGCSVVKVDAEPGDLIIWDSRTVHYARLPESETVRTILYATYTPASLASPEDVALKADIFHRYEATTHWPHCNIFGQGKAMRHGEVCSGERDEPLEKPVLTDKLLKLAGVKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS41</accession>
    <name>A0ABR3YS41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="32"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="518" mass="57086" checksum="A84D6DC987ACCA1D" modified="2025-10-08" version="1">MRKLGSPRGDAFWVNFVTNLSGERIGVLPYERMDVGVLDATPELIHNIPQPDFEAFVANELDGDPNVEIRKGLAYITSTQTDGGVSTTVEERATGVQWTVLSRYVLACDGAKSTVRKDLGIQSEGEDGYETMMTIHFQSDLRPVVKDRVGMLHWITDPACSGFIIAYDLGENQVLISNFDSKRHPVESWNESLCRDVVGAAIGQDIPFKVLSHRPWLLSRKVAKQYRQGGIFLVGDAAHSFPPTGGLGLNCGIADAHNITCKISAVLNGWARPDILDQYEAERRHIALICAAQSVKNGKKIFSFLKTLGTAGIDDVEEARANLHKSIHDPAKQEMIATEVAGQQEHFDNLELHIGYVYGDKSTPPHASHYTPKFVPGARLPHAWITPLEYDLFDYLEPHDVSYVKEFSLSDIAARRYSTLDLVKPQSFALIAGPGSGWKEKVEAIQQDLPGVRVLVRLYTVGVDFDFVFPEQERFFTEAALASSGALLVRPDQHIVAKLSSSTTADVAKTAILSELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS57</accession>
    <name>A0ABR3YS57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CoA-transferase family III</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050483">
        <property type="entry name" value="CoA-transferase_III_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207:SF3">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="50312" checksum="A05D732582224850" modified="2025-10-08" version="1">MLRPSLLRFLAAEQRSRFSTSRPRHNAIVTATPSGPAGALAGVKILDLTRVLAGPFCTQILADYGADVVKVEHPKGGDDTRLWRDAGEKDFWKDGEKTSLYFNTINRNKKSIAVNLKNAKGRQLVLDLARQADIVVENFIPGKLDQLGLGYAALKAVNPSVILASISGYGATGPYAHRAGYDVIGAAEGGLLHITGEPDGVPTKPGVGLMDMCTGLYLHGAILAALRQRDVTGGRNGGIGQHVDTSLFETTVSIMANVGMSWINLEKEAQRWGTGHPTIVPYESFPTKDTFFVIGAVNDRQFEILCRLVGQEARSKDAKQGSIEDTCALSDVDIASLPKSPLYSSNSARIQNRVTLKNLLAAQFRTRSTADWEKIFAGSGLPYGPVNTLQQVFAHPQAQARRMVETVPQEAAVSGTVKVLGMPVKFSETRPTVRTGPPGLGQHTDEVLSSSLGLSESQIAELRKEGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSI1</accession>
    <name>A0ABR3YSI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007983</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="151"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="151"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="277" mass="30566" checksum="2315C14ACA6FC120" modified="2025-10-08" version="1">MDATQMSPLMFSVDLNGSIIHTIIEPSILAQFWTSLAIQVMPGSDLIGIPGPTFRILDEGGKRYIAHNYASAIGEAMVKFVIDGSGTHPDRYFLGRAAFFRPENIATCTEDLDVWVPPGYPLQNSAPVPSVGAPVSASSARRNARGGAVKVPRPPNAYILYRKDHHKAVKQSNPRLSNNDISIILGRQWNEEVDEIRVHYYKMAVDIKRQVEALHPHYKYNPRKSSDIRRRNKGNNGVYNVHNATSETPQDAATSTLASMLTPPLDFETAASPSSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSI3</accession>
    <name>A0ABR3YSI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein tms1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TMS1</name>
        <name evidence="8" type="ORF">Sste5346_007769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="466" mass="51359" checksum="996C92911CA9B632" modified="2025-10-08" version="1">MVCSACGKCGNSVATRIGYALILLINSILAWIMETPWAINKLEHLMLDYVKINCPTGQCYGWLAVHRINFALGLFHLIFAGLLIGVTSSRQPRAALQNGYWGPKIIAWLALIVLSFLIPDEFYLFWGNYVSLICAMLFLILGLILLVDMAHSWAEYCLEQIENSESRVWRVVLIGSTLSMYLGSIAMTVLQYVFFGRGGCSMNQAVVTINLILLLIVSAVSVHPAVQEYNPKAGLAQAAMVAVYCTYLTMSAVSMKPDLTDDKHCNPLLLAQGTRTTSVVIGAIVTMLTVAWTTTRAATQTLGLGGNRTGGIRLPDDDEDDVHDSNSNYSAHGLVTTQPSRREMRAEALRRAVAEGSLPADAMLSDDEDDSDDEDSGRGGRSKSGDDERGATQYNYTTFHIIFFLATAWVATLLTMNYEDSTRDGDFATVGRTYWATWVKIVSSWVCYALYTWTLVAPVVLPDRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSQ8</accession>
    <name>A0ABR3YSQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41082" checksum="A79AC7B60745FE5F" modified="2025-10-08" version="1">MASDLLRVLVGPDHREFVVHRAMLCDSSPFFRDSIDAVPEGLTTPSSPSSSPSSSPESTPPPSSPSQPTTLIWLSGESADVFELFVVWLYRRHAFRSVVEDAVTILAREATSHEVITLHPQVHRDSHNNNNADSDTPPSASANLSDLHWHLVRLHLFAAIVDIPVLQDAVMDALQDLYLRFDWTATPALLRFLYIEADPLAACRLRKWAVALLGWTLANSGEDDHAELRSLLVLAPLAEEYDAHTRKMKASRADARIKNPQLRISSNQLRREDRHFGFRQCSFHSHRRSAGEGRCPHERARRRGTLDFVSSLALPLDMPSGRKSNLHSPSASLSSLSSTTSEPRLEDLPVWSPLSVTTPGYAPLGMESTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSW1</accession>
    <name>A0ABR3YSW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-lactate dehydrogenase (Cytochrome)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007654</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF148">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (CYTOCHROME)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="113"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="477"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="56261" checksum="473103FC22C31135" modified="2025-10-08" version="1">MALSAQEISKHNSTDSCWVIVRGNVYDVTEFLPEHPGGQKIILKYAGRDATAAFDPVHPPDTLDKYLDKSKHLGPVTDMAAVVEADKNRKKTPEEEAEAAEDAAVAEARALMPPVDSCYNLLDFEAVARRVMKKGAWAYYSSAADDEISVRENRAAFQRVWFRPRILVDVERVDLSTRMFGARVAAPFYVTATALGKLGHPEGETVLTKAASRHQVVQMIPTLASCSFDEIMDAAEGPGNPYQWLQLYVNKDREITRKIIQHAEKRGCRALFITVDAPQLGRREKDMRAKATALGDGGSSVQKKEGLASDTSQGAARAISSFIDPSLCWDDLPWFRSVTRLPIILKGVQRVEDVVRAAETGLVDGVVLSNHGGRQLDFARSSLEVLAETMPVLKARGLDRRIEVYVDGGLRRATDILKALCLGAKGVGIGRPFLYAMSAYGLEGVDRAMQLLKDELEMDMRLVGARTIDDLGPELVDTRSLTSHPNGVPDDVLSQRTYDPLQVPASRNSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSY1</accession>
    <name>A0ABR3YSY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="196"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="368" mass="39437" checksum="0D3BCDD23312871A" modified="2025-10-08" version="1">MFLRQCNQLTLDAFSDANPEVPPAGHKSSRESSAGRQEVRLPTSSSVCDVLDATWSDAAVSQGLRRTASPLRGTPLRQRTSIPQATVAASDNDAGEQRKRQKTRVPAEDIDAEAHLSPTPPAQATPDVLAKPVAAKVMGNGKCGIWTATMFSRSKALIQLTNKLATGYHASLPCSSRTPSATYSKTLILPVDSSNPGAGETVSGTGLSEATAGGRNIVAGWAFAHKPGPDGVVSGQLEPVGLDGEPYLASRNRADLRAALAALEYCDWAKEDGVDRLVISTASYYMAKGLTSWLREWKIRQWHTVSNHPVPNRDLWERISAVMGEYAAAGCETSVFYTARNRFGSKLEAAAQRATRQPSPFNTGPYPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTG5</accession>
    <name>A0ABR3YTG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="40261" checksum="DFFB130E629D2D15" modified="2025-10-08" version="1">MAGKIPLKLQVAIRDYWEKETSSVQVARENLKKVLGYPIRIDPEWLQLLGDLDKVYPDKQSLATAVAGCVELWCKVFTELLEGADNADAAQQEWAETLVDRLEPHIGLRLFVTVTGSDATLPIVTEPGTSWSEDRSSFLLYLPHKRAVTVPGEFAAVYRGGLLDCFKEKKPAPPSLAVRSAAATSAAAGGGDDWADVEMDAATGKAAVVEAPAPTSYAPATATASAPEATIPKLEYLPSLESLPRPDELFLRPPYHLIVADYGKKKIVIQGSHSPSLRLLGEYMKRWCRLNHQDSRNPPAVEVQYNQSCWGSSPMHDQVTLSSEKNNIFEFNPAMVLAFVEGVLGYDKVSTEQGIWTYRRMVPFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTH1</accession>
    <name>A0ABR3YTH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="15"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="504" mass="55656" checksum="B50FBEFA06D7ABA3" modified="2025-10-08" version="1">MFETFIQGNRLRWLARISCSVSFFLEGYQAGILGGVQDTSQYLDAIGNPTGTYVIPMIASSYTLAAAAMSVLAVVVGMPLGRRNSIMLGNILIIFGGIIQAASFSVAQIIVARVICGFGIGLITCNVAMYMSEMSIHARERGPEVAINCASLLAGVAISYWVDFGFTQMSTQFSWRFPIGLQSLWAMIPAVGMFFCPDSPRWYYAKGREVAGDTTLARLHGVYNPDTALGEEDERIIQQVKAEIMQSIQLEAEQENKLSWISLVWDNTPLRVGRRVRISFIILSIQQMMGIDIMVYYMTLTFRGVGLSVFLSSLLAAVCLTVQFGGALLCIPTIERMGRRNIMLITSSAQSVCMLIFVVLVGLPSSKITDATQWAAAAILFPYVFFYGWGWVTCPWLYGPEIAPLKYRHVGAAAGLFGEWLFTFVTVFAGGIGIQTVGWRIWIWPLVFNFVGVAFVYFMCPDPTGKTLEEVDALFVKDASLLNRLPHGVDEKTNTQEVEEAEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTV6</accession>
    <name>A0ABR3YTV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="32"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="450"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="544" mass="59260" checksum="7A782B4DE5311D48" modified="2025-10-08" version="1">MAPIISDVVVHLRTDRSVTHMMLENPSNTAPSDIVCEDTLTGKTATYGGLRTDAFAAAHSLRHHHNLKSGDTVTIIGRSQVDYIVAAHAIWAAGCVVNTINHSSTPKEMLHALQIVKPRLLIVDVAVLDKVRRAVDSLDSVDKPAIMTLIKRVPETPLFPDDLISPGQRVDPSAYVLDGRDARQVCAAIVLSSGTTGLPKAVMLSHHNLVCICEMLRGHNPDNWRGSSQREIFFPPLSHIYGLYVCALMSPWLGSYVCMVPSFDVETYCRLMHEKRATLARLVPPVALALSKSTAVKKYSYPSLEYFSCSAAPLTPVVANQLRRQFPGVSLCQTYGCTELASCVAQSGVRDEGKAPLIAAGSLLANMHVRFVDEDGKDVSPPTPGEICVSSPTIMMGYKDNAAATQEAMLEPGWFRTGDVGYLDANGYLVIVDRLKDVIKYKGFQVSPSELEEVLFQHSGVQDVGVTSVWDDAQATELPCAFVVPKTSGSEELAKDIMAMVASKVAGYKKLTGGVYFLDVLPRNPTGKLLRRELRKIAQTRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV10</accession>
    <name>A0ABR3YV10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051709">
        <property type="entry name" value="Ub-ligase/GTPase-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622:SF58">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="3">
        <location>
            <begin position="9"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="36"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="93"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="228" mass="24268" checksum="AE74DAD61F978B3D" modified="2025-10-08" version="1">MLMRSFTMTKTAPISIRNVVSITSGEYHSFAIDTRGHVWGWGFNGFGEAGDSKSPGRDSASVSLPIKIKALSGRGVVHLAGGAHHSAAVTSDGTCLVWGRRDDGQLGVDFTPEELADPTLIRHDDRGRLHICLQPVVVDTIGPAAHVACGTDHTIFVTRSGTVYSTGFNAQGQLGLGKEYEDIDEIHVATQVVGGKEIQNQKRHITWAGASGQFSIVAGPRIVLGVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVF0</accession>
    <name>A0ABR3YVF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CGR1_3</name>
        <name evidence="10" type="ORF">Sste5346_007411</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="48"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="123" mass="14125" checksum="C2FE58EDC6C7D08D" modified="2025-10-08" version="1">MSSETTAAAPAAALVAAASTKPLGMRKNGKQWHEPKKAFRPGSGLTSYEKRNKERIARATMKAKEKELKDEKEAARQARTKAIRDKKAAKEEKERYEKLAEKMHKKRVERLKRKEKRNKLLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVG8</accession>
    <name>A0ABR3YVG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L35, L29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl35</name>
        <name evidence="4" type="ORF">Sste5346_007427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_uL29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="14243" checksum="15B8DE7A729F2D0B" modified="2025-10-08" version="1">MSSSKVKAGALWPKSKDELVKQLAELKTELSQLRIQKITSSGSKLNRIGDVRKSIARVLTIINAKQRAQLRLFYKNKKYLPLDLRPKQTRAIRRRLSAEDAARTLTKTKKRQSHFPQRTFAVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVU4</accession>
    <name>A0ABR3YVU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="567" mass="62938" checksum="9E6612AE5C2EFA0F" modified="2025-10-08" version="1">MVSKKGSKKSSARSSQTPAQPGSNTSTGAYEKLINRMYEPLVLLHALDPIRGDHIATTNPPINNAQHIRRQFRDDLAFLCEYDKGGDACTALGIEDREDCLIYWVAANANPQKKIEPFLVNLLGDLAAVIREGGGTDTSTGTARLQTATEEVTAKCAAFALPKIKKICTLLRIRISDCEECLGGGSFSDEEKQLAVWLQQFKQSTKDISAAGAGLDLCRLAYDRRKSREMRQLKQLALEQGHHGVSRQCFAQAHHYIGRLADHVRVPPRLVSNLQYVEDLLLNPLSVQVPPMAHCAPCEPLRQEHGKRQSRLEGIISRMCKPHEKALLAELAAGLQDFSQNYDLDAIVHKKFADLTEKSKAPRVHAEVQILEHFHRNKLDWADNGDRYIGCSKPACFCCHLYFRHHPLRPVMPGTHNKVYPKWGPPLLDGGTANPGYIEQRDLLNRFIEDVRKDVVEQIRAKRGPSKRWQADTATAITQTVAGDFDGVVHVGDDSGFESSDFGDYTLDNSRSDDNSSSMNDADPTPVEDLSRDLVYLDLSSYPDADSDSDPEDGGVDVREWSSPGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW30</accession>
    <name>A0ABR3YW30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bis(5'-adenosyl)-triphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HNT2</name>
        <name evidence="7" type="ORF">Sste5346_007155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13893"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.29" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047710">
        <property type="term" value="F:bis(5'-adenosyl)-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051884">
        <property type="entry name" value="Bis(5'-adenosyl)-TPase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243:SF1">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="6">
        <location>
            <begin position="9"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="115"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="210" mass="23077" checksum="EE781C9DE0C7DC8A" modified="2025-10-08" version="1">MSSTTAPPEKIFFGPFDVSTQVFYSTKHSFALVNIKPLMPGHVLVCPKKAYRRLTDMGADEVLDLFASVQVVQRMLAAYYFGEVTAREDDANDCYKGSFNIAIQDGPEAGQTVPHVHVHILPRIRGATAKSALTEADELYEKMAEEPGNVGGQQWDAALAAAHTSQFGDRPQPGGKFPKIEDSTREPRTMVEMEAETAAFRETINKVLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX15</accession>
    <name>A0ABR3YX15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF16">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="123" mass="13668" checksum="2D4DFED29688C822" modified="2025-10-08" version="1">MNSEPVGGKFPYNDSLAAVNDFYRFYLVEGAGHCSPGECNTSFPQTNFPVMIDWVKNGIDPVTLNATGPSSCATNYLANDQLCSWLLRPVYENNGTKKVCEFPSEAAFNTWIYGLNAFPIYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXB2</accession>
    <name>A0ABR3YXB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP-1-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YAP3</name>
        <name evidence="6" type="ORF">Sste5346_006786</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF8">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="159"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="68"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="126"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="351" mass="37835" checksum="4F51FF4FFCFB214C" modified="2025-10-08" version="1">MDYTHQFFAGTQPFQQQFIGIPPLTPSHSNSATSDDYTTTSPPEGFHDFANDHFPAFDNYGVQFAPQHQQNIFPGPPTPPGQQLPLGAVHAGQQQPPQPQQHAPVTSVPAAPIAPTSAMVIDQDVLPATKPDPGMIEDLQQQQDQSRRGGSNSDDDEMTPAQSRRKAQNRAAQRAFRERKERHVKDLEAKLANLEASQNKTASENEKLKRDLQKVSTENEILRATSSLQAAAAAAGASPGSDGAGGPIMTTGPMTYNPTDFYTDLLSNHDIKTPSHRIATSDAGERLLGAGATWDLIIGHESFKRGLIDVADISNRLKTQAKCDGQGPVFEERAILNAIEQSVGSGSDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXT0</accession>
    <name>A0ABR3YXT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="621" mass="67441" checksum="32473672EE0AF8D3" modified="2025-10-08" version="1">MSYDIDVLIVGAGPTGLMLANELTAFGISLRIVDKAPIRSDKSRAIVVQSRGLELLNRHGLGQALMARGTVGQGIDIHVYGRHAASLNISDFDFKDTAFSDTLLASQADTEDLLESHLLNKLGPDHRGIERPATILSIVADADGVNVELIHGEDSETSTDIEKLRCRYVVGCDGAHSSVRHAANIAFEGDAYLQSFMLCDAHIKNWDDRPKGRTQMFWDKGFMTLLPYAESKGIVRLIACRPLPVDAAAETRAQQEQPTLETFQQFFADTAHFHGENMPELCDPVWVTAFRLHHRVAAAYQSGRLLLAGDAAHIHSPAGGQGMNTGLGDAANLGWKLAAAVRAAQSSKATTSTLGLTDTLLLSYNAERRPIGERLLKTTDKMFIAATTATPFFVWLRNNVLRFIAPLVVRVRRRREQIIGSMNQLRVRYRRSPVVGTAPGWKGVVRGGDRAPDGKVIAAGAGISDVSHLLEHLWQGGKGITSYHLLLFTGTPSTSWFASVASKAAVASATTKSIVAAAESASTTLAPVGFDATVAHIIAGSPEQAEAFVEQEQRSVFVDKDVYLHGRYGFGSKPGYALVRPDGHVEHVGWLTSLPQLTEWVDDRGAATAAAKASRPWWKWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXZ9</accession>
    <name>A0ABR3YXZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LYR motif-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20262">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045293">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF0">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="7">
        <location>
            <begin position="57"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="122" mass="13839" checksum="80CE86D7703C0FF3" modified="2025-10-08" version="1">MNRIAGLWLSLRSSSVPAHASFISRTYATAGSAGPIRTSRLGGKTALSLEHFLQRSRALALYRTIVRGTRQISDPTTRAETLRFAREEFERHREVTDLTHIRYLISTGKTEWENTERYIGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY35</accession>
    <name>A0ABR3YY35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006449</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="436"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="844" mass="91425" checksum="F7446D50C9D0C7B7" modified="2025-10-08" version="1">MKTEDGGIDDLLPSLPPPPPPPSPQAGAKATLYTNGSADSAQTGPSQQSKRTVCDHCRRRRIRCDGQLPCQPCVNASLACKRDHVPLKRGPKRGRGRVINELRERYSIDQSNPNASVNQNNKHSRESSIDLINGIDMSVPSTPAPPSDISWQKVSSDPRHAAEPRGAFSTEQYRPTSRSYMYLMPRLIDLYYEHIYPIMPLPYMPAVRDMVNRSPAGMAELTFSDRNYLYALCALTCFHMSGQNITADAPHPSWECAGRYFLDECISARQSYDFFNDSSLHAVISSFWLSTSFFEINQSRKSWLYLREALTLAQELALHDDASYAGLDAAETLCRQRTFWQLFVTERSFAILRSKPITLKKTPSLPTTRHPYEAPEIHTGFRQLISSYTPLDESFVNAWNEGSDPRVTAATYLALQAVLAMRPPFLAKARTEIKTVTHGLSTTSNTPEDRSPTGHEAPPPSPSSPAAFSAGLNAALGNAAGVNGDEEEIKQENEPETTDIQKADLLITQQWLRLIVWQSSFRQQLLSWTAPDESMRFAFPLTIAARTAAVIQSLPPQAIEVHGMGIFEKIFEIGTWSMNVLQACDMASASGTNVAGGGAAMGMDFAGASDMGVLGVGRMSYSVDPLEFFVRTLSASPNSRTQYAERLLMFANEQTGGGMRMALSPALSSPSSPELLPTGHWSKDEVTTTTTAGSQPPITDTNGTNIIGTVLGEVGDDFNSVSAVNHFASTGPNGEAVPFSFDANALTDAAFEIGPVAYDNGSLDGVVYDGTVSPTGVSVGGGSYGSIHGGSINEGISRNHSYGSFTEELQAGTDYPVFLPSAAQSPTEVNGFAGFDLSQTNLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z067</accession>
    <name>A0ABR3Z067_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006166</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="812"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="823"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="915" mass="98504" checksum="509951C7545F05BB" modified="2025-10-08" version="1">MNGNKRQRTNSDAVASSDRGSERPEKAAKPLLTRACAECKRQKIRCFFAAGQSACNKCSKSGIQCVPHNFAQKYMDDDAIWKAEATETISRLTAAVNYLLEQNNMPKLATFGKGDKALSANDHPTTRENGNATSPTATGDATTAVQSVSPAMSQASSTAVAATTAASGNFISEGPSAELQEDDSDLVPLPMNNLYNLTDPSKSYLIRVDPTCVNGPDFISRGVVSLEEAQFLFSHFITHINPLLWDGILCAHTTLEAARASSSLLVATVLTVAAMHLSGERKDTANAPDTDRQNGNQNDQQRQQHQQQQQQQRQNKPTLLHATYDAFVQLMRASCLLRSQNLDDIRGLCIGAFYLTSLSWALCSRAIRVATEMNVHKSSLQFAARGVARPTSSTSSPSMPGQPSSSSYGNDQFERVQLWYVLYVCDHQFALAYGRPPSMHDDASIRNADKLLAMSESLSFPSDVPGPIPPPVSRNARGNRWLVAQVKLFRILAGAYFLYGCDPDLALSGEDYQRLQSFNLSLDQWRLEEQQQHTRGGGGGGSGPMGVLPVGLTGDWPSRGYPTDDRQAVSNKVTTLYYHLARFQLNSLSLRGISARGNDGGMGAGQFGTTVGTAAISMSWERQEAANNAIAAAASTIRLIVEDADLRSLQIGMPIFVHAMIAVCASFLLKMAVVFNADSSNNGRAALPLSALPLPRDLSRHGLNFHTKNALADVESLVRVLGAVADSTSQQHVVRQVVTGLRELLQRFRPGSEPDTFVYLRSTIQGVVHNGAQNGNSVQSGVPGGTVPANSGAFDYANNEIPRTAPPAYSMTPHGNGGLPMHPNTSHAGHQQGHDQQTMSGSDGNMGGFNVGNGANANNGVPYAALPQGQMPSDSVMQPSAALAYQDDPFNLMGDLDWRFNDAFLWGIQAEPPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0G7</accession>
    <name>A0ABR3Z0G7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pin1</name>
        <name evidence="9" type="ORF">Sste5346_006710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051370">
        <property type="entry name" value="PPIase_Pin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657:SF4">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="81"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="192" mass="21486" checksum="F3B8DF9904CBCD70" modified="2025-10-08" version="1">MSGENREETGLPPNWEVRHSNSKNLPYYFNFVDKASRWEPPADTNTEQLKLYMAKYHSGNSAASGDAAAAAASQQQQLQQAGKIRAAHLLVKHRESRRPMSWREAEITRTKEEARQIIQGYEEQIQRGDITLGELALTESDCSSARKRGDLGYFGKGDMQKEFEESAFSLRPGETSGVVETASGLHLIQRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0M8</accession>
    <name>A0ABR3Z0M8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24732" checksum="E5B4901ADAFE11E9" modified="2025-10-08" version="1">MAAPASKNIHNLNGKWQMNKSLSGDFGAVLSLQGVGFIMRKTIGAASITLHTTQLEGPPAEPTEDPLDDAAKTESVTHINIDQTMTGGIKGTTERRCVDNRRREHTDWLFGHVSGRTLFYKGADAKAQIAKDFPDPFLLEGWPDDGEDLLVSYVLNLDKDRGWEATQVWGFQTAKDGTRRYVRNVVVTKGEGSKQQRVTVQLIYDFLGERDDEKSEDAELTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1T0</accession>
    <name>A0ABR3Z1T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribonuclease H</fullName>
            <shortName evidence="10">RNase H</shortName>
            <ecNumber evidence="4 10">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="12">
        <location>
            <begin position="198"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="144"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="351" mass="37749" checksum="A341DD7319F0F8AE" modified="2025-10-08" version="1">MPTPAATAAAGRKRKLDDKNVQKFYAVRAGARPGIYLTWNECQAQIAGFKGAQYKSFVTREHAAAFVAGLNPEGGAKDKGEPRFYAVAIGKFPGIYTDWAEASKAIVGAKGPKYKKFSTRAEAADYIRMYANDATRQALSGLGGNAAAGVNTQQAVEEDEDEEEEEDDEDEEEKDAAQILQPANKRAKQGSSATSASSTAVLDIYTDGSSLGNGKNGASAGVGVFFGPGDKRNISERLKGTLQTNQRAELTAILRALQSVPVTQPVRIFSDSTYSINCVSVWYKSWASNGWRTRGGDSVMNQDIIKAVRTFIDARDKSGTMTMFRWVKGHSSDSGNVAADMLAVQGARQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2A7</accession>
    <name>A0ABR3Z2A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RET3</name>
        <name evidence="14" type="ORF">Sste5346_005711</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="10"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="197" mass="21729" checksum="ABC57E80B71BAC01" modified="2025-10-08" version="1">MAPGLSLYSVKAVMILADDGSRVFAKYYTPPHQAATGAPGSTTNPFADVKAQKTFEKGLLEKTAKQNSDILLYDNHIVLYKAESDVTMYVVGSPDENEVLLYNVVLTIRDSLHLLLKQSIDKRTLVECYDILALAMDEIIDDGVILETDPSIVVTRVSKAPTNDVNIGRIDPFSEQGVNQLAQMGRNKLSDWLRQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K3</accession>
    <name>A0ABR3Z3K3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-taxilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="248"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="35321" checksum="7BB2D243A2207B56" modified="2025-10-08" version="1">MNGHAHDTRPAPPPPPPPPAASAASGSAQQAPAPAPVPSKAKAARRQPTVASNEASKLVAQKIAQLELDQAGEKDQEIEIEKEVRKANRELNSQTAKMDAAQKIDHLSRRCTELLHDMKRHERESLKNKKRADQLQKDRDQSRTDLSKATTLKEKLEKLCRELQKENNKLKNENRTLKANEVSNLNSWDQKYATLLQKLDDLQEEKDHPKKQIVDVEPELLFRERFKSMIDQYELRELHFHSLMRTKELEVQYNMARFERERKRAEAEVALSQRLQEQVAELSRSEAKMQAEMKLILEKIEQANLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4F1</accession>
    <name>A0ABR3Z4F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MYND-type zinc finger protein samB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Suppressor of anucleate metulae protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005335</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MUB1/samB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051664">
        <property type="entry name" value="MYND-type_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442:SF1">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="12">
        <location>
            <begin position="769"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="175"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="240"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="405"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="677"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="682"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="815" mass="86668" checksum="FD40D7C237E21F4E" modified="2025-10-08" version="1">MREVNFSIPNVNKASVGITTALYDRRALDCTSTLPLINSLNHLAYLTTSSARIRDILTVDGGIERLVCILKQGRSKDMMDMWKWNLAFQCVVNIGVRGTEAVRTRVVEADMVPVIATILDNYIKVIEKCREKAEEAKQRHAQEHQGRHRGNDLRVANKSSSFTYRTLNGSRFDLDQHRSFRRQAPPPSIDVSATFSGPTSVAGGEQTGASSAASSSSAAAAAATAAAAGTATGASSTALSAASSTDGSQSNTDNDATPTMSQFHITSPAGPQHSARSSISSPPPVPAHSSLPSSVAHTPASASTSASTSAASSARRFHHHHHHHHHHHVGAAGPSSSSSTAASSTATTPVPSSAAVAATSATPSRHALSTPGGAAIQPLSSAAPSATSVSGSEVNEANLLRAMRDLDQPPPYGLTRPLLGNSQPASPTTPLPPPQLRSPTVRPTSLLAPTGRSRRRPSIRHQNSTSGPAAEVDDLNAESVQSDETPDAEMSGTAEIQATVDIQDINMEESESMLGGESLELTTPTVSETQDTGAFNITHRGPLDGSITPAATTAPVPAMGLSPNRPAMVTTQQPVMPTASVPRYLLDRQLTPHPQVIASMPREEDVLMSLQLLAYVSKYCNLRSYFQKSHLVPRLKIGKELQLLDGDDLTGVDGIGGASGSGHGSGVAAGKMEEDVDADNDSNISGSIGTLSNSSTISGSSSSSTGSFDEGAEEEEEEYLLPNDLNIFPLVEKFTVRYHSTDMQYWAGVVMRNLCRKDESRGGIRQCAYYQCGKWEKFTRQFAKCRRCRRTKYCSKECQKSAWAFHRHWCVAATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P2</accession>
    <name>A0ABR3Z4P2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cholesterol esterase</fullName>
            <ecNumber evidence="5">3.1.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TGL1</name>
        <name evidence="5" type="ORF">Sste5346_005440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.13" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="100"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="540"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="588"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="652" mass="71020" checksum="01C1B95868B35F6F" modified="2025-10-08" version="1">MPVPFLGRLNVTEYTALISSFFLVAFEAIIRILTLALPISTSIRDASDFVELCRLFGYTAEEHVFQTKDGYLLGLHRLAWRPGEEDKKVNAGPRSLQKRVIYMHHGLLMNSEVWVCTTDAQRCLPFVLVERGFDVWFGNNRGNKYSKKSVKASSKSTDFWNFSIDEFAFHDIPNSISYILETTGQKSLSYIGFSQGTAQAFASLAIHPKLNDQVNVFIALAPAMSPAGLSNGIVDALVKASPQVLYLLFGRRSILSSATMWQSILYPPLFVRVIDLGLSFLFGWKTENIALSQKLAAYAHLYSYTSTKSVVHWFQIIRTKSFQMYDDDVHPLLATHSKHTKVAKYPTRNIKTPVVLVYGGSDSLVDIKVMMRELPAQTVATEIPHYEHLDFLWARDVDVQVFRHVFDALDSFTGAEHTKEEYARFRSARHTSLSANNSFHVPILNSADGNLALAPTQHTHRLSDVTSDSDSRSQTRATAVELIEEPRPQRSEDDLLLDDDATWSQPGTPPQSEPAIIVGASSGNKTATRALSTALEHAPAAPPLTDRSPNAAGPPSTSPVEASRSTSSSAVPSGTGTPLGGGADAGSRPSSSHSTTQTLCKTSSQKFRNVSGGSLSIDSKRGGKGGSIRIGSSKAVGGVSIDSASAVGSLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y9</accession>
    <name>A0ABR3Z5Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Multifunctional tryptophan biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Anthranilate synthase component 2</fullName>
                <shortName evidence="16">AS</shortName>
                <ecNumber evidence="16">4.1.3.27</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">Anthranilate synthase, glutamine amidotransferase component</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="16">IGPS</shortName>
                <ecNumber evidence="16">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="16">PRAI</shortName>
                <ecNumber evidence="16">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="primary">TRP3_1</name>
        <name evidence="21" type="ORF">Sste5346_005621</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="16"/>
    <dbReference type="EC" id="4.1.1.48" evidence="16"/>
    <dbReference type="EC" id="5.3.1.24" evidence="16"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016302">
        <property type="entry name" value="Anthranilate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001377">
        <property type="entry name" value="PRK00278.2-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001382">
        <property type="entry name" value="TrpG-trpC-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="18">
        <location>
            <begin position="29"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="19">
        <location>
            <begin position="248"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="20">
        <location>
            <begin position="605"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR001382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1894934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="769" mass="82780" checksum="47C1EAFD465F6673" modified="2025-10-08" version="1">MATSPDIIDHSPHHPQPAERIPTASNVILIDNYDSFTWNVYQYLVLEGATATVIRNDKITLDDLIALNPTQLVVSPGPGHPSTDSGVSRDAIRHFSGKIPIFGVCMGQQCIFDVYGGTVDSAGEILHGKTSPLAHDSKGVYAGLSQLLPVTRYHSLAGTYGSLPPSLEVTSWIAKEDGTKGVIMGVRHKEYTVEGVQFHPESILSADGRAMVRNFLLMQGGTWAENEALQAKTKAAGGAAPSKSNNILQRIYARRKECVAAQRVIPSQRFEDLQAAYDAGAAPPALSLVDRLRQSPFPVALMAEIKRASPSKGVFALDIRAPEQARAYAQAGASVISVLTEPDWFKGSIEDLRAVRQVLQSMPNRPAILRKEFIFDEYQILEARLAGADTVLLIVKMLDDETLARLYKYSQSLGMEPLVEVQNADEMTRAVQQLGAKVIGVNNRNLESFEVDLKTTSRLRSMVPEDTILCALSGINTRADVVENEKDGVNAVLVGEAIMRAADPAKFIRELCSGAILPPSTSTSPSSRTHPLLVKICGTRSAEAALEAARSGADLVGMILVPGTKRFVSDETALAISKALHEFEGEDDGAPTTVSETYIASDFFHSARTTLAHHHKRRPLLVGVFMNQPLDYVLAKQKLYDLDIVQLHGREPVEWAHQIPVPVVHKFGPGEPGVGQRGFHAASLLDSGGGSGAQLEVSAVQAELARDPSLTFLFAGGLTPANLAGVLTALGPEASSRILGVDTSSGVETDGKQDLAKIRAFVQAAKTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6X5</accession>
    <name>A0ABR3Z6X5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="32346" checksum="48929D3100F1B845" modified="2025-10-08" version="1">MARIFLRSSRVHEIKPDRKSLNLEVHFADPLVTVIEEIPKPPKKPSKHPSKYSSKHSEHSKHSSKSASKSSSITNASSSSINYFDVVERGRKLSAPADMATPNLPAPTIYLEESAIPVINNANTTVDGYYYVFDKYQFRRMMARYHRHREECERASEDHQTTIGVSHSLIPCLASAPDLEEIPEEEEPEEIVREPWVPPVFVRHDEEHEDEELEGLTPQLCLDPVINHQVYIVDAAAVSVSSIGSLVASSLHTIEGNYVGFYDCIVLFFRHGFRAIFGQHNQPLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z755</accession>
    <name>A0ABR3Z755_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CCR4-NOT core subunit cdc39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CDC39</name>
        <name evidence="12" type="ORF">Sste5346_004532</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="11">
        <location>
            <begin position="504"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="10">
        <location>
            <begin position="689"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="9">
        <location>
            <begin position="896"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="8">
        <location>
            <begin position="1187"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="7">
        <location>
            <begin position="1835"/>
            <end position="2217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="851"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1666"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1672"/>
            <end position="1685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2221" mass="246787" checksum="9D40D6065C84CB6D" modified="2025-10-08" version="1">MVPPPRAGTFSPSPAQSLHTGSSHSPHPNQSAALGGSPVTGSPTGTNTVSKIVIAQVYVLLSSIKEDDTNKWEQLQKLIDENGMEVFSKYFTRAVASSASQIFPGYSNRPGGTHGQYIAVQKEMSDIAHNPEKARKIAESIETGNEEIFRDFDLSTFMEHFKLDALEKTILALAFKLGSRSDLKTKADAILSTNFPSFLNILSRPGVGTHADMDDSFVSLTVDRYIQLHPPNFTSAAKTELSLKVIQRYENEELGPPPSVLAALDLMRVLADQPVNSLANLIHKTGADFTRDEDTAVSHLQKGHYTEVQVANALTYTTISQSYVYNPSVLVAALRRVVSPKFQWQEVIGAFDQPGARISTPQFLRLYNALVPIARDDETINIERLWGGNWVNPDSQLSFVYAYTSQSPDDLDAKTIPNIRSTFAIEEYAEAAPEIRERAAVAAKHPLVSLDAVSAIVKIALASQHASINVEARRLFQAVVIPNLDIFVVSAAMVPKPWPLTAAETFTSLFEGFLYKKTPNWDFVFDSLWRKDRQLVTEQLINAHALHPGDLPEIFEHCAKHGWLNDLVYLPNGFGLDLVAYAHGRGFVDLTEWAKNNAERNADIARPLMQFLVIKSELEAQRPDGQQIVPKVNVPLKVQTVSALLSILEDYYPTTSPNPDLVMLQRQCIAVYPRLINYGEGFDEIIEESEQAGHALPQEANTKMEEHFKKMYSNEIEVREVVRIMANYKTSRDRLEQDIFACMINSLFEEYSHFGDYPLEALATTAVLFGGLMSHKLISDLPLKVGLGMILEAVRDHTQEHPMFKFGMQALMQLYSRFREWPGFCRQLLQCKSLQSTEALKKASDVVHEAEEDARAAGGQLGGDEAMTNGNGDDGSTEQPPFISINVDPLPPNIPFEDPDPDAQGKIQFVLNNITASTLQAMFQEIRPMLDIQHQQWFASHLVEERAKMQPNYHKVYLQLVSHFEDRMLWASVLRETYVSVSRMLNSEATMQNSTERTHLKNLGGWLGLLTLARDKPIRQRNIAFKQLLIEAHDTKRLIVVIPFVCKVLSQGKHSNVFKPPNPWMMDIIHFLIDLYHNAELKLNLKFEIEVLCQNLSIDHKSIEPSGEILNRVAMEVPTDLHDGLDTFENLSLNGIGHAGVGAAAALAGHGMVPGVVANSMVSMIPERITKVHVPPVSDMVVSQTRLEEIVRNALVQALQDIIQQVVDRSVAIAAIATQQMIHKDFATEPDENRLRTSAVSMAKATAGSLALVTSKEPLRANFTNYMRSLSQDLGLNLPEGTIIMCVNSNLDYASGVIEKATEERAAYEIEDMIEPEIEARRRHRMQRPNEPYVDPGLSRWAMTIPSPYKLNPSVNGLNSDQMAIYDDFARHPRPAAASAASAAHNASASDTTRSLANDVLQDQYSSLASIPSAAETPSVASVGSQLQGYPQLHGANVAGGVNSGLMNGGRQAGPNVDVRALLERVSKLMHELQRAATDAPEEHFSELPRPHPVLDIIDAVIQTIIKAQQSVEDFAVYAADQICPMLFNPQLEDSLAYESVVHVLEQLRKIVGMPIFNRIAQFFQAQPGAAFLRLGLIQALLPTGLLDWSAIDNATSTMLKNRKEGSIAFFTRLLELTIIRDGPPALLFYAQFFHSLSEAWTWVQEQPDTPGGQEFKMAILTHGAPPPQPEGGANANTNANSGTLTQQRKDQIEYVFDEWVLVSQKPGIPDNILFIFMEQMREHGIVTNRDQLYEFVRVAIDRSVERFEVSAQAGETNSDSFAAIDAVATYVALFVQACVPENGDAVVPEGQSPRAVLLNSILALGTMILNHHYVQHRELYNQRVFFRFFSMLLVKINDLPSEKLSDTDRSEILLRFAMSFDQMGPARFHFFAFAWVELIKHRLFMPPLLRVAGNEGWGLFTKILKQFLSYTSELLKMPEGPQMQMARLMSRAALKLLLIIYHDHPDYLAANHVELCQSLSPYLVQPLNIVLFASPSSIPKPPDPTMPGLRLDQMDEASTVPDGRYQPKPLLESMGLTALLDRALESGPSEEVVAHVKYAMSSRTDAKSSSSSSNGSIGTNTTWHRVPISTSVSVVDAVVAYIGSHVAARVSSGGPVFSAGGPDVATLSMILHELSAEGRYYLICSIVNQLRFPSAHTNFFALALLDIFGHDMSDPEETDIRQQICRVLFERIVNYWPQPWGLLAVIAELVKNEKFFFFELPFIKIAPDVSERFAAVANRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7G2</accession>
    <name>A0ABR3Z7G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-1-phosphate guanyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MPG1</name>
        <name evidence="15" type="ORF">Sste5346_004910</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05824">
        <property type="entry name" value="LbH_M1P_guanylylT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="13">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="14">
        <location>
            <begin position="254"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1896167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="362" mass="39741" checksum="5ACF0ECDFBFB962B" modified="2025-10-08" version="1">MKALILVGGFGTRLRPLTLSMPKPLVEFGNKPMIVHQIEALAEAGVTDVVLAVNYRPEVMEGRLSEIGKQFNINITFSIETEPLGTAGPLKLAESVLRKDDSPFFVLNSDVTCEFPFKELVEFHNAHGDEGTIIVTKVEEPSKYGVIVHKPGHPSRIDRFVEKPVEFVGNRINAGLYILNTSVLDRIELRPTSIEQETFPAMVRDGQLHSFDLEGYWMDVGQPKDFLTGTCLYLSSLAKKDAKQLSTESYVHGGNVLIDPSAKIGKNCRIGPNVTIGPNVVVGDGVRLQRCVLLSGSKVRDHAWIKSTIVGWNSTVGRWARLENVTVLGDDVTIGDEIYVNGGSVLPHKSIKANVDSPQVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7I0</accession>
    <name>A0ABR3Z7I0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial intermediate peptidase</fullName>
            <ecNumber evidence="9">3.4.24.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">OCT1_2</name>
        <name evidence="9" type="ORF">Sste5346_004651</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.59" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046344939" evidence="7">
        <location>
            <begin position="25"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="74"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="207" mass="21076" checksum="4072836F6F8AE5D9" modified="2025-10-08" version="1">MRQPRLTTIAAAALLLYWVGAASALSTTASTSTTTTSASTTPNATQTTHTTPTVYIASLAPTTGAAAATGTARNYGYQGCYLDISGMNGTAPGARSLQGDTTDEVLPGDMTVAKCLSFCGGAGSGTAYAYAGLEYARECWCGQELSSLATKEAEAQCNLPCDGDNNTLCGGDLRLTLYMLKSPATRPDIAFGAMAAVAGLTAVVQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7U7</accession>
    <name>A0ABR3Z7U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">mns1B</name>
        <name evidence="13" type="ORF">Sste5346_004887</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123556" description="alpha-1,2-Mannosidase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="528" mass="57617" checksum="B1E4EC520032B57F" modified="2025-10-08" version="1">MHIPGGLLGAGTLAALATSASASPTTSRRNLKPKYVAHPDRVDAIKQAFQISWDGYYKHAFPHDSLKPVSNTYQDDRNGWGASAVDALSTALVMENEQAINQILAHVQNINFDTAIGDISLFETTIRYLGGLLSGYDLLTTPGALNGYSANKTQLAAVLSQAQHLADNLKVAFDTPSGVPDNDVLFDPPRRGNSSTNGLATIGTLVLEWTRLSDLTGEPLYGQLAQKGEDHLLDPQPKALAEPFPGLVGTNVNITTGEFVDGNGGWVGGDDSFYEYLLKMYVYDPVRFAHYKDRWILAVESSMKHLASHPLGRPDLTFFAMFSGTSPRFVSQHLACFDAGNVILGGLVLHEPRYVAYGLELAASCHDTYTSTVTHIGPESFSWQDDGRLAPVNSSNNTAPPAASADFFKEHGFWISDGQYILRPEVIESYYYAYRATGDTKYQDWAWDAFLAINSTCAAGSGYSSVNDVNAANGGSFQDFQESFWFAEVLKYAFLIQAEDAPYQVQVEGGEFVYNTECHPVRVAGKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8H8</accession>
    <name>A0ABR3Z8H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="379"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1194"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1329" mass="142035" checksum="A4E68A68F211D520" modified="2025-10-08" version="1">MSDSRRRSSRSSSTSHHRSSKDGSSSSSSSNNPYSSDSVSNGSSSSLSSRHRSSRHSSSSHSSAPSNRSSSSLHRISGSSSNRSRESLAPSTPSDRHERHSSSRKSGGSSSHSSSSHSSSSTLQPPATDPGPSTNTGGIYGNLAGRASESRFSLTDQFASTRSVLDFGFDDSASSIFDAQSIFSVGTARAPSLYGYDGYEAAAAAAASIGGGGSGLDPFAELGSMTPTASSVGGNGLQGSPWQPEEEYLGGAYSTVLEENEDEDDTATIGGGRDDGSGNNDDNDLTDDADTPGSTPTKPKRSRAASSADVTVIGADGGSQKSPSRDAELLDELQDPLRLPVPVLPPSQRGPRPGLGGATQSYATAVPPARIPVAPIHRTYYDIFCLSREQFPPPSGAQIRAAYFRLFRLLNSAISNGSAPSQSSSNPNKTNLMPTALRPFAAAYFLEVQNAFETLIDPIRRLEYDRYLDDLEDDQTANDLDDDSESEVEGGKIKKSEKAGTASTTPAAYPQTQGPAFVRKYDFQTTTDLGARYTVSGGLDRRPGQLLPTAPNVASFDYSLTQSVRIGLPTLRQYTEASLFQLQCRIQRVRRILHERYGVGSGAATQNSFKSRDGRTYYYTRRQSSAGGAAVDQPLWPIRCGIPIVSLSASTYSLSTAAAAAGAILPLGDRYQPLLPEVLGPARIAQLAHTRASGCVVLGYRQEFWTGSALANPPGSAPGPPPPSVVVDLETEVLPRVAVTARVAQTVQLPTAIQNLERSVFGCSHEPINAEVMMQTGESSLFSNPPSSPIVPRFGLGLSRRVGSGNLFLCADSGNSWWSSLTSSSAAASLFTPFIPPMVEVGYSMSPHQLGLHSGRPLTGPADRGLKGVDIDMDTLGSVATYSSDRRNPVPSHGTWTVSAATTGYGSAAAYLRYGRTVFLTPLWRTPPSTPATNFPRGRRQRQSPQRAVRVEAELCAADRYFSDGYIAVRALAPVRWWGLRNAWTSNATTSFRSSTPASTTPPKIGLEVALSAGSGNVHISLYWSRLGQRIKLPFLLLPSPLSLASSSSLPVSHTAAKLFAYVAIVPMAVMAVREVARIYWRAAAKQWKSSRAKARARKRALRGEVVETEDTDTGSDFVFDEEEEQAITRHRAEADELTMILASAVDAQRVLERQMRQRSDIRSLDDGDESNRRNELVIISAKYGVALADDPDDLEGGHARHDSATSGLGHGIAASPPVTAMASRNGWAPDYEVADVTAAVSALIVTGGSGTDATDSDYLYIPAGLQKGRLLGFWDPAPNYRTKQNDEEAAAMSSQRRSRGKKVLHVRYMWNGLERVAEVGDRTELRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8J4</accession>
    <name>A0ABR3Z8J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031833">
        <property type="entry name" value="DUF4748"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41800">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41800:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15932">
        <property type="entry name" value="DUF4748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="118" mass="12837" checksum="E0B4139E280E5D59" modified="2025-10-08" version="1">MNTVKSFWLGWGSLCVAGGAAYYFAKKSINADRQARLHEQRRKKSVLESLEHNDANASAIASQLAARTDAVGSPSQESSNTDPAPTRHAPATEAQRVLEKSKYEASAPFRSPKGDRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAJ7</accession>
    <name>A0ABR3ZAJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sister chromatid cohesion protein pds5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PDS5</name>
        <name evidence="7" type="ORF">Sste5346_003984</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1349"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1353"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1363"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1446"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1491"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1517"/>
            <end position="1529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1529" mass="167096" checksum="A3A31A95B84EF727" modified="2025-10-08" version="1">MAPARRRAPARNGASAKSPEVADTATPESNNEVSLPRRAAAPRKQQQAASRSRGKKAADPESEPEEEEEEADEEADEQDDEQPQTGRAATGAAQAEGPLVSLGFNEPLSWRPGKPIPTEELIRRLETLSHELSDLDQETFDTESLAKVAKELASHNLLNHKDKGVKAFAAACLVDILCLCAPNAPFTQTQLKDVFGLFITYILPALQDPSNTYDAQHKYVLHSLAEVRSIVLLNDLDNSDALQLQLFSSLFDAISAPKNVSGGRLPTDVEHDISDVLISLIEEGPNVPPKVVDVIMAQFLRAAAPGALRDKGVPDKDELDRYQSTLLLKEEPPAYQMAELICQTCADKMTRSVAQYFSDVIIDFSGVGNAAGNGKGPAGNKGGKGSDDEEDEDEGLNGPSESDLREMKKAHLLLRELWRAAPQVLSNVVPQLEAELSADNVYLRKLASETLGDMIAGIGAAGPPPLPTLDPAAYPPPRLSDEFATRATDSVLTTPTSPHSFAQTHPHVYQSFINRKNDKSALIRTAWVTAAGYILSTSAGGIGLSREEETVLVLGLGDKLTDSDEKVRLASVKAIEAFNFRDVITKLAPHGGVSKEGSVLSNLADRCRDRKSHVRIEAMALLGKLWAAATGELAAGDEAVIAALGGVPTRIFNTIYANDLELNLLVDRIAYEYLVPLSYPAIKKAQKASNGRGSQQQKSAMSTGGIDADAIRAERILLLVRSLDAGAKRAFFSLQSRQPQFSSIVDGFLKQCEAFNGGVGEEGKKATPGLEKSIQYLSQFFPDAAKVRADLQRFAKLNDRRSYQLVRFVIGPEHDFTTMYRAMKELVKKVQGTNSSTILDTLLPLLYRSGCIMFNRSHLTTIMEYSKAGHEDMAATANEMLKEVSQRNPGLFKTTIGELCKELATQAPTETRENDPIVIDSLKACSSYAAKYPQEVPRDRKFVQAWINFAVYGRPEKAAKYAVSILLATKDEKSMVSATELAQKVTKDFKFESPRFLNKLVTVSQLARFAPSVIADTEDELRKQTMDILRTVRSTSSASDPEWADDADLDDEIKAKVQCLKFLVQQLLGTKDIEEAKKDGKNIIRFLIKFITQDGEVTKSKDTPKHHRARLRLAAAQAILKISASRQFDELLSPADFNTLALVTQDPQPQVRRGFIEKLQKYLVLGKLRPRFYTIVFLAAFEPVTEFRNQIETWIRSRTRYFQEAKQNVLEGVIARLISLLAHHPDYSAEADDLVDHARYIIFFLSNVATESSLGLITKYAERVKQTLDGINPENSENLYVLSDLTQATIRKFQQRKGWIFESYADKVGVPQGLYSPLPSHDVAHEIARKQYIPEGVEDRLDDLLKAAERKKAAQHAAKRAKTSSSSRPSGPSRPASGSKPASSGGASSSRKAASAPKAKSSSAKRVAKPSAAKASKSSPSARIPDSERRRSGRSAVAQTSYMERDSDEDDEEMLDGVAEWQYLGSGDEEAGTSATRARDSGGRRRQSKSGAGGGRASSGGDSGIWGRSLRQASTDSEAEGGDDAEDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAJ9</accession>
    <name>A0ABR3ZAJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BUD14_1</name>
        <name evidence="2" type="ORF">Sste5346_003991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="149" mass="15856" checksum="66F1981D8DA532DA" modified="2025-10-08" version="1">MTRPGMIRAAETLRGVAAETAQDRRISWTGSNLSDLHIYGSDLATDIADTLNLSRNLQESALETRAPASHLNMTGNQQQDALAIAQNGGDVVEEDMEDVDDEELEDDMMDKISSSPSIEDGAYTKSPDLLPNLSAGAVVTSTACAASRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAT0</accession>
    <name>A0ABR3ZAT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin interaction motif protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055335">
        <property type="entry name" value="Ucp6/RUP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597:SF1">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1106" mass="122908" checksum="0C52FAAC3D6A4DC2" modified="2025-10-08" version="1">MEDPSEASIAEVCEFANLDPISDRQLVIAALRAKSGSIQDVVLAFYDDPSNFRKTYTWDESSFMGDRDGYNNSPLPSFNIQGPDDNNGSANVIHGISPSQYHSVPPSRPPSRTQSPLSRMADWTANDVTALTTMNQADEDLERALAMSAAEAFGTDAAAAMNMRPQQESGVTSSHDYAHDYSVPTNLPFFGPANREAYDPNQWAMVRASPENTEPPPSGRKREPGVPVFLRSRKSPSEASMLGAILTILHAIPGARNAMLQSGLQQATYGQNSEWWKGSRIEPLGVSKNDIHMASQAAAATTTITIVDSDEDENGVDSNMTDGGQIKTGPKMDTEFAREFVEEVHRLMAFLDSTDRAYGTADGLTETAALKECFGMETSQRFFEAARRLKIPEFLQHFFFSVQLTPLKAMGSPIRSETYAILEIKVDNTHLPFGLHDLYTAIDIIFWEDVYKFDLDPEKKQMALEDASMATLTKVAPVQIFRLSTPKVVPFQEPFDVPEFFYLDRYMDENSVRALEIQVHLHKVYANIRKIDAAIQEVTTYADYSDNNDKPVNRDRIILSEQAITFAFQKEWQFRAEMVWGRYRAAHNTPQQFDYSVAEIYAAEPITDEEKATLQVLRSEIAVHRQKLIDITNKSQRLQFQRESLIELARRLRRKFTAPSEEENWRPTNKYALRGIIVSPDKFYFCRREAPPSKTSQSVDEASNDLLIDLEESEIKGKEKETEGAEPKSSSSSSSSAPVDQWWMVSYNAKDASPITVQKTTMDVARGSVFQESSSPVLIYSTDASLEVDNLPLSDALRTFVRFDNRFFKQETLEESPRGDKKRQPAEDASPTSPLKRQQRANSIDSMASNMASLGEFSDRDMEDVPLLDVGTDSFKSNNGDRFPIDMDEGVFAATRGVDDGYNVHEWALNRTMEEALAKRAEADGSDWPDPSIIPQREVDLLPGYDETVAYNNSMVTKAPPPVIATGGLFNDHRGSIGTEMVQLAIHGGGSGSNDANGVNGATADADADKDTDNTTPRATTTTSPDHSHLEAGSGSGSQMQERSRSRSQSPGQMLPPPPPRPKKPQHLQGNKSPEKPPKNGEVQLLADWDNPEGRYVVHAEDASKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAW5</accession>
    <name>A0ABR3ZAW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="41"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="593" mass="63543" checksum="0FD440CAD85DAB0E" modified="2025-10-08" version="1">MAEPKPDIDHVEKDASHSVADSDDIRGADFTVDESDLPKGYFRSLPFLGSMLALGISFACGVGGFAFAAPILSYINADIGPDPNLTWVALTYTLTTGVCLILVGRLSDLFGRRWFMIGGACLGTLGTIVCATAQDIPALIAGETLVGLGASCQISFAFTLNELIPFKYRLLANGYIYIWGLFASGFAPVISYAFVFNTNVGWRGVYYLLLAMNATALVCWFFFYYPPTFGMKHARQRKIGFIKNFDYVGTFLVTLGLLLFFMGLSWGGQLHPWKSAYVIATIVIGAVLLIVFGFYEAFVPLREALLPTHVTTHRDFMFAVTIWSLGSAIYYAFAIIWPTMLVTLYGGSHADNPMWPGYAALALNGGISFGEVVGAVVTKKRIHNIIQATLFIGSALLAATASCTPDTPARAIVLMFLGSSFIGWLEVVSSTYSTLLVKDQRELGTAIGFAGSFRSTLSTICSTVYTVILSNRLTENISNMIPPAVENAGLPASSVAAFITALTSGDTTALQAVPGMSPAIIVAGTNAYQLASAASYRTVFLSTIAFGGIGIIFSIFLPNIDHLLTSEVSTTLHSGNAEEAVTVPKDDAEAQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBF4</accession>
    <name>A0ABR3ZBF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004096</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF63">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="168"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="473" mass="52770" checksum="30582C32B9393255" modified="2025-10-08" version="1">MTDTRPRWRRTVAAIVVACSVAYVLLFVPIYAPRVHRVPLSSPFPATSPFNNLHLTETECRSTFPGLMDPIDEQVRRGPFQLQPASDLGPLQARVRGGQLRIVSTEKHGLLPPELLDARVATLHQINRALLTAPFLSSLRSREESMSSLPSSSPASLSSPDGSDSLDDSLDTVFSINIQDQPYGSAFTYSLPAYAAPTAGNAPIGRAFLMPHFSFWAWRPPMVGSFARASAEIDRIEAEIPFSRKKPQAVWRGTTRFSSAHHPELRKALLTATHNQSWADVQALDWLPDGSNANAMQEASNSLMIEDFCQYKYVIHTEGITYSGRFQFHQLCGSVVLTAPLAWMQHTAHLVRPLYASDLPLEGTPWKPTADEEKAWPHSTPNEANIVFVSPDWSNLGATIQWLEKHPRVAEDIARRQRQLFASGPYDRGYHSPAAEVCYWRGLLAGWKKVVQYNDTDVGEGEPWESFSLDPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK4</accession>
    <name>A0ABR3ZBK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_003866</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1898008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="13"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="474"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="500" mass="54499" checksum="D2D33BCB07D4EBEE" modified="2025-10-08" version="1">MAVIKANKYNILVAFFVALGSFTYGYNSSVTAGVVGLPSFFAYMKIDTATSQGNALFGAINGVYLAGGAFGCWTLAWLADTVGRVRTIQAVTVICIVSAAIQCGSVHVGMFLAGRLVNGFGVGMINTLIPLYQSEISPPSQRGRLVGLHGAILVAGYSCGGWTSYGAYFATNKELQWRLPLAIQLLAPIVLLVGSPWLPESPRWLIGHGREEQGMTVLSSLHRTAEDPDATGACLEFREIQNQIHIEAEERIDTLWKCLCTSDVRRRMIYGFCLQWLLQSTGVLVVFNYQTVLYANLGVTGSTPLLLLSVYNVVAAIFNYICSLVLDRFGRINIITFGVAGCIADLILYTALVSEFANTTNRVGNGFAILALFLFAVFYGFLDSASYVYCSEIFPTSVRAHGMGFAVSGLFLSNILYTQVAPTAFDTIGWKFFLVFIIVPAAGLVPFRLFYPETKLLSLEEVSYLFGGTAPEAGDEKQQVQSDRDPRVSENEETIAVRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBY5</accession>
    <name>A0ABR3ZBY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_003948</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="74"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="367" mass="38902" checksum="1BBB657F7CF543A3" modified="2025-10-08" version="1">MGRPEDVEAQLNGGSNGSNVNWDKGRNGPLLPTSNVGSGIENKLNNLDSLNTKNAASSGAEAEYTVSAATKYAYLSAYFACNVALTLYNKSILGKFAYPWLLTAIHAGSASIGCYILELRGLVKRSELSRRDESVLLAFSVLFTINIAVSNVSLAMVSIPFHQIMRSTCPVFTVLIYRLRYNRTYSTKTYLSLIPVVCGVGLATYGDYYFTAAGFILTFLGVVLASVKTVATNRIMTGPLALSPLESLLRMSPLACGQALICALLTGEISSITSGFTNIPISPHMALALAGNGALAFALNISSFSTNRQTGALTMTVCGNVKQSITVLLGITMFGVKVGLANGLGMLVALIGAAWYSVVELGAKTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCP5</accession>
    <name>A0ABR3ZCP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylglyoxal reductase (NADPH-dependent) gre2</fullName>
            <ecNumber evidence="4">1.1.1.283</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GRE2_2</name>
        <name evidence="4" type="ORF">Sste5346_003904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.283" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043892">
        <property type="term" value="F:methylglyoxal reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05227">
        <property type="entry name" value="AR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="346" mass="36873" checksum="583F7320FA8D930A" modified="2025-10-08" version="1">MSKVLVTGGSGFLAGHILKQLLMADHSVVTTVRSEAKAQSTQATYAALGFPADRLSVAVVPDITCDGAFDNVAQTPGLSAVLHTQSPFHFNWTDPQTGLVDPAVQGTTSILKSVHKHAPGVRRVVVTSSFAAMLSGAHLEDPATTFNEESWNPVTINDIHAAPGAAYAASKKLAEKAAWDFVKENKPQFDLVTICPPNIFGPIVHHVDDVKGLNTSSQGLAALLQGEWSKEIPATDGVCLWVDVRDCATAHIKSLDTEAVKGGQRLFATAGYFSNKAIATAVRENFPEYAGKVPIADVAGGDEPALDKRFKFDNAATNKVLGIQWTTLEQSTVDAVKSLRFLLAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCW8</accession>
    <name>A0ABR3ZCW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="582" mass="64287" checksum="C8E69B78D280ED28" modified="2025-10-08" version="1">MAAENEPLLVVYQKGEVQPHIGDFDTAGLHESAQDVYRAAAEARRLRHRRKVRRCHHFLALTLLVVIGLYTRWFGLFHFFRSHSWGNDNNDFVGLGSTPLDGPLVLPDSSFCSAHRTPHAYPVSSYPLAFNGDHDLVIHQNTTRRWGHHHGNDDSDDHDHDDNDYRWRRVRVTGEVVVRQVVGDKKPSIDVEALSNDKRISTTYVFDKDGQRLQVIVDDRIWVEKGEWQSGHDACLVVRVTVWVPEAAKEKSKELHLKSLHIGAVHLGVQLIDNLDLIVDESARLASVVGSIVASRALPDAEAASKKDEKVDCMSIAFAPGYRFEAPETSVTTTASPIRGPWSLLDSLHIFSVSGSISVAVRPEGTADDHKDKDLADLRIETVSGSIGFEELKEEKDDKPAARPHRLSVVTRSGTAHGSGTFAQSARLHTTSGNIAFALAPHRLAENAKDGDDYVPAQLDTDTVSGKTVIYLLNETTDNTAVDFLESTHHAVSGSVELHYPASWVGDIHLKTVAGGSLVVEGKGVHVVPDDSPRWPPRIGRKVDAIKEGTREEDRDDDKSEEHRSTLNADTVSGRVKLSFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCZ8</accession>
    <name>A0ABR3ZCZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="886"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1414"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1520"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1917"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1527"/>
            <end position="1555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2261" mass="246640" checksum="819E202C4130061E" modified="2025-10-08" version="1">MSTSGTSVPVLVAAFVFGIVFNAASAALFLHVNSHGSTVFRDGQRLVLTTFLLGAALWAQTDFISIAIDPTATSSCQIGIIFSTFFDQLARFSIEQYLLWAINKGAKSGVQQMALQALVVTRFVVGCVFVGFSRPQLDSVCVPTSSMMPVAIVVVVLDVVLIVTLAVMAIMAGLMSDVREDNSNAGRSKSILLVIVAFTIWTATSVVMLLGMTSSDLLLRTLLPAIGLLILVFIITACNDPLTTGSTKSTRAPDSPGIRNITTGRSISTDASSDYPPSRFEDIKRSEIMAMSAFEQPREAPRPDVPPMPSNFSRPVVMLANVEAPPLVVQNEAFAPAASAFAIAAATSNMRKVDIRPLGKNKRSLLDLKGGPGAGRGGKMTISNPILEANGDQNPLNKIATISLEEAAKSERERRANDLQRESALIAKRPAPQPPSMSTKEAMKRSVSLKRKEVASVSSQPPIPSMSSLEPMPVATTSSAQLSPGVEELRRRSPRQSPVGREADRSMRTKSIAMPSAPSPTIPLPSPQQEMPRQINNMDQNNLPEQMNFTVEPNRADGAFIIQPAIFAPPMRPARPDADFPAAPIGVDTGVGRPEIRPSRQLPKTPTQAAPEAPKPPLLRRPTNGLPGNPRAMALKALNNEQNAGQQQTVMFMNNIVYDNPETVQDIIKDASTKETKRRSTQSIVHRPRPIPRHLEKDRAIFPAEPSPNLAGHRRSKSGGSIIGRKSILLSNPGSPTQLPPLPLPPKNMVYNMARPSADRPQPNNTKSMTFDEKMTLLFPTPPSGESLARRRSSVPEMPAMPLDYMPIILSPTEGYDRDNRMSQSTNRTGRTSIKTENILEVDELPRRSEDVSRLNDEVGSAWLPGLAGNSMVMSDATMHPSMGATSMTTGGRKRASSPVLPPTRDSTMTMSTDVRTHDDATTIWGSVHSPVVAVPIPTNRQVARTTYINGGERGEGHNLAPAAAALKDNSGPLLPLLPATTYNAGGKTTSQPASDLTLSREDNAQWQKKIEKRESQWHRRVGDDTLSFSDRKERVRSRKMPPPTPLLLNPSSTRNPVIVKAAEPSPLESPEQALAHIQEQLKRYEEPNLAVTAEETPTRRLALLDNLEREMDMQAGHWQEMQHDLRHDSLSSMQTLSPSAESRRQSVISSHNVAAAAAVPQLQQQQQKQQTSKESVTIHIGADRRAARRSRIQASTSAWSKSTIDESILPRISAPTAGSLQNGANKKSPFPNAVIDLGALGSPTPPDSDSDDLDLRLHRPYDTLDVAFSDSVTKALSQKTALTQIQKPSLWTPAAAKLATMTTTTLLWTPAPSVQSRQPTVLFASMSVSSTKKSQAGKKQLSGPLPIESVTLWTKHANQTSQTAHSGRGLWMSLSLAKPVPAVPAVRAVVASREPTEEEIMMQKMQDLESEMDAMEADREERIQSSQKAPRPVTQRPPRRNKRVTMLPDILESPKPLPDKRGTLGIFQFPWGERSDTAKLPTMPTRGGPFGAMPGTMASGGGQLNAALEARARELEASEYSSSFFDDYDDEEDYDDDDDNGFDEDASGSDDGFDETTLWEIASLLKTEQVPSTLSMFPPPLSSGSVMGDYIDDMPSDNEMDKINYVDVDEVLVGLANENTKRDSQLWNDRQDTTGKNTKDVSMAQPDEETWKSYDTVSQAATLRSKPRKSESASIETDQLWDTKANSKPSTIKTLPANPRSSLWAAAQQKKMEAEKKAAFLTETSQQQTDNNMWAPRTKKTKGLNTTKTTLFDKKAAEEAKMEAAVIRTTDLEPAALNMPRTPRTPNHAPLEKLMSTSLWTSANGKTSQMWAPKPVAKVRAKGHLFDRDVAAVEKLNKPTRTTDKEPAALHMTRTPRTLSHAPLEKLTSTTLWASASSGTSRMWTLKPVVKVRAKGPLFDRDVAAVEKLNKPTRTTDKEPAALNMPRTPRTPNHAPLERLTSTSLWTSTNGGASQMWVPMPVPKVAAKGPLFDRDVAAVQKMRLPIRTTAMEPAAVDMVRVPRSLSHLPQLRLESTKLWSVAETSTHHVQKKTDYNWILAKDPKTLPMVVDDTIPASSIGVKQKTWWEKMKAAAGVSSAVAASPVAPLAVVEAEIDSVRMALKTTPLLPVSQQQYLERPAASHSDWEEALQEAVAASYPWLQRRISATPNEWQAALNQAMARSYPFDASLQHPVLAGSSSPAPLFVSNDASKLHPVFFQSVKEPKAKEEVVVQLVQSETVAQTTAEADAAYHAHIMAMENNALARLQALESAGHGVVLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCZ9</accession>
    <name>A0ABR3ZCZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949443" evidence="1">
        <location>
            <begin position="24"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="188" mass="19710" checksum="A87FF57E3B7AEB0B" modified="2025-10-08" version="1">MKFISSYIFIALAALGSTAQAQALATTTPTAPGLEFLFSCNISMGLSLKVGTGVKNTTRAVFPISGGQAVGPRLQAKVLEVGADWASYGTLLNGVNVADDATASKDPKATTFFGTDARFQLLTLDGANILVETKGQTAPGTTTGAVHLRAHLETTSVAYDWINDILAIGVLRTNSDGYQIDLWQLTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD40</accession>
    <name>A0ABR3ZD40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003467</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="392" mass="40994" checksum="B07329E32C6E3180" modified="2025-10-08" version="1">MAPTVVILGGAYGGLQIAHSLLKNNKEAKVVLVSKNSHFYWNLASVRAIVPGSVEDKQMFVSLTEALSRYPKERYEVIVGSAEGVDTAAKTVKVAIPGTAEPRSISYDQLVLATGSRNTQPEKRAGAGADEAIPATPWKADGTYEEITALLQATREKVKAAKHIVVAGGGSTGVEAAAELGYAFGGKSEDKGGKQIVLLSSGAEILGSDIIASSARNELNKLHVDVRTGAGVTAARTLPDGRIELTVAGASEPLITDLYLAAVGLTPNTEYLDASLLNDRKNVEVDEFYHVKGVASNDVWAVGDVVSKPRAGFVITMKQAGGVAKNVDLVLKGKSPQVVKLLPVDVMVVATGPSRGAGRLNSWRLPSLAVWVAKGRTLGLNMVAGYLNGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDY3</accession>
    <name>A0ABR3ZDY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal transducing kinase of the PAK</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">STE20</name>
        <name evidence="10" type="ORF">Sste5346_003514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="723"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="216"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="282"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="473"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="580"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="625"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="662"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="752"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="991" mass="106946" checksum="89A74040D2C53626" modified="2025-10-08" version="1">MDSGGGQSLNTLSSNGTSHQQQQQQQQQHRRRLTKKPPPSSYHHSSSTSFDGRTIETQSLQSKRSSTSLRRAPSAPQTRTSFSAYASSSTSSSPRHQPSGGAPSFSNPSPILAGSDFLTADYQQYQHQKKQQHHQQQLFSSTPHPSYSYQNNASIAAAASAAASAPSNRMNHSAIPDAFARTPSHGSALTSPSEDFVGAPFDGAAILNRIEESATPTPIPYASHNLQPSRNAPAPPTGNNTTMQASGFSASASGGTTPSTGTANASNPAITAITTTTVASAPVTAAASPTPSNEMNEKTPSAQSGTSRPSGGSGSDSQFPGTKRYSDESREFRGAGMLRKKSGFSGFMTSLVGSPKKPLISAPENPGLPKEWQRLINESGITEKERTQNPEALMQVITFYKETTEKAQEDQVLEKFHDARPGMPSHANSSASLTTPSPSVPAGGVPAAYNPMSPLISPPASPRFPLVNYEGSFVNPRSPPPVPKGPGSSAMKDINLMPSRPAPRPPISLPSRTAPQAPFPPTKDSGIGMSHQQDDGSSQPPIAPPPKDNVPMLPEEHRSRSNSRVTAPYQPTGAGMSSTQANAAAQAAAYQQQLLQQQQDQAIAQAQAAMTGQLGRAASTRQQPHKQLQQQQPPLGHAQQPTPPQSQHHQFGRSPDVNGAGRSPQAQPYPAAATTTQQQQQQLQQLQAQARPRQRPRASTATGIDISTRLRQICSDGDPHRIYRGFNKIGQGASGGVYTGFERGNNRLVAIKQMNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLWEGELWVIMEFMEGGSLTDVVTYNIMTEGQIASVCRETLKGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATINEAQNKRTTMVGTPYWMAPEVVMRKEYGRKVDIWSLGIMAIEMIEGEPPYLTESPLRALWLIATNGTPVIKEEHNLSEVFRDFLYFALKVEPDKRASAHDLLRLSPLVRAAREAKAQEKARKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEI0</accession>
    <name>A0ABR3ZEI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myosin-1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Class I unconventional myosin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Type I myosin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">MYO1_1</name>
        <name evidence="22" type="ORF">Sste5346_003415</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01378">
        <property type="entry name" value="MYSc_Myo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11858">
        <property type="entry name" value="SH3_Myosin-I_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035535">
        <property type="entry name" value="Fungal_myosin-I_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010926">
        <property type="entry name" value="Myosin_TH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036072">
        <property type="entry name" value="MYSc_Myo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF837">
        <property type="entry name" value="MYOSIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06017">
        <property type="entry name" value="Myosin_TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51757">
        <property type="entry name" value="TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 17" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 17" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 17" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 16" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="Myosin motor" evidence="20">
        <location>
            <begin position="54"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="TH1" evidence="21">
        <location>
            <begin position="786"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="19">
        <location>
            <begin position="1106"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="17">
        <location>
            <begin position="601"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="966"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1166"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="976"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1032"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1063"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1095"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1166"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1182"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1213"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="147"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1898511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1254" mass="138464" checksum="AEB199B70BD23D07" modified="2025-10-08" version="1">MVGPQSLRDRLVDLGITRRPNKQDKPDRAGGGGRSGGAARPKKATFETTKKKEIGVSDLTLLSKVSNEAINENLKKRFEGAEIYTYIGHVLVSVNPFRDLGIYTDEVLDSYRGKNRLEMPPHVFAIAESAYYNMKAYKDNQCVIISGESGAGKTEAAKRIMQYIANVSGGTGTDIQQIKDMVLATNPLLESFGNAKTLRNNNSSRFGKYLQIHFNDAGEPVGADITNYLLEKTRVTGQITNERNFHIFYQFTKGASDAYRQNFGVQTPDTYIYTSRSKCFNVDGIDDLAEFRDTLNAMKIIGLSQAEQDSIFRMLAAVLWTGNLVFHEDDQGYAAVSDQSVVDFLAYLLEVEPKKLVSAITIRILTPRSGEVIESPANVAQAIATRDALAKAIYSNLFDWIVERINQSLKARQATSNSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKTEQEEYAREKIQWTPIKYFDNKVVCDLIEQVRPVGIFSALKDATKTAHADPAACDRTFMQSLSGMSNANLTPRQGNFIIKHYAGEVAYTVEGITDKNKDQLLKGLLNLFQVSQNQFVHELFPNQVDQDNRKQPPTAGDRIRSSANALVETLMRCQPSYIRTIKPNENKSPSEYNVPNVMHQIKYLGLQENVRIRRAGFAYRQSFEKFVERFFLLSPATSYAGEYTWTGSYEAATKEILKDTSIPPEEWQMGVTKAFIKSPETLFALEHMRDRYWHNMATRIQRMWRAYLAYRAESATRIQRFWRKKRVGAEYMVLRDQGQRVLGGRKERRRYSLLGSRRFLGDYLGINATTGPGSVIRSATGISPNEKAVFSCRGEILEAKFGRSSKPSPRTLVITNSKFYIISQALINHQPQITVERAIPLGAIKFVGASTARDDWFSLNVGSPQEPDPLLNCVFKTEMFVQMQRVMPGGFNLKIGDSIEYHKKPGKPQLVKVLKDSQVPVDFYKSGAVHTRAGEPPNSLPRPTPPAKPVPPRPITRGKLIKPGGPNGRPSRITAPNGRKPQPTPAARPAANTSRAVPPRPAVGRVSAAAAAPTLTPRPVPSRPNPAAVAAATAAASATSTLPSHTRTKSNTSAVRAPPPPPPPPATPAAMTAKVLYDFAGQKDNEMSIKAGQIIEIVQKENNGWWLAKINDKQAWVPAAYVEEVVAPPPASSRPAPPAPPRRPLGGAAASRSSAASSTLQPRDSGMSLNGGGSAYSSDGSRTNTPTPSASGSMSLADALLARQSAMSSRKEPDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZES3</accession>
    <name>A0ABR3ZES3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Very-long-chain enoyl-CoA reductase</fullName>
            <ecNumber evidence="11">1.3.1.93</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TSC13</name>
        <name evidence="11" type="ORF">Sste5346_003280</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.93" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102758">
        <property type="term" value="F:very-long-chain enoyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF28">
        <property type="entry name" value="VERY-LONG-CHAIN ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="167"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="37281" checksum="A6C790CFA9941075" modified="2025-10-08" version="1">MADKLTLAVSNRAKSGTIKKLPASIDVTTASTIEELQQKLAKASGVKDYNRIGVFDPVTRKIIRDRRAVLGAQENVVNQMAILVQDLGAQMGWRTVYIIEYAGPILFHLLFFYLRPIIPLPASLSLGQTASRSDAITDIQRLVYVLFQLHFLKRELETLFLHRFAANTMPARNVFRNSAFYWLLAGFACAWSLYAPLSPFRVSSNFPAASPPRSGFGTSPLDYVGITLFVFGEIANFSVHWHLAHLRSPGGTEKKIPNAFGSSLVTAPNYMFEVISWLGVILIARDIVVVIFISVGMLYMRMWSRDKERALRRLFPDKYKKKKYTMLPGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEV0</accession>
    <name>A0ABR3ZEV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC multidrug transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_003138</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="503"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="909"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="949"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1054"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1144"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="286"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="616"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="913"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1250"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="857"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1516" mass="165207" checksum="5F06234BC39B59FC" modified="2025-10-08" version="1">MDSSSCGFVADTRFGPGIVSCRREFDFTLLFEEAVLTIIPAGTFAILAGAIVLIAYLHKSPALVRTGRLYPLKLCSVAALAAAQIAVLILQARVPNKTVASIPSAVVSLIVTAIFLPLVSHVEHFTSRRPSALISLFLTLTCLFDAARTRTYFLVAKDSSSPERLAIALSATVAIRLVLLYLETKGKKELLILLDENEKVPAEVLAGPINRTVFHWLNSLLIIGYRNALQATDFGPIDDRLLSFRLRPMFQRVRAQYESAAKTATTTNRLIVLTFSSLGRLLAGPIIARLAVTAFSFTQPFLANAALTYLQSEADPEHPISRNYGYGLIGATALTYVGIAAATSWYWHQAYRCAIMIRGGLAGVVFDKLMKLPEGDDIVSKATTLVVNDVERIMRACARGHEVWAGTIETGLATWLLYRQLGPSCLVMLGVAAIAGLASTQSVKRMGARQQQWLAATQRRLKSTKHMLDSLKGIKMTSQDDVAYDMLSELRAAEIKDSAPFRWIIVISCFLSYCTMILSPPLILGVYVGVGTAGGGHQDFSISTIFTSLVIIALLSSPLVQLFQVLPGLGAAHGCFGRLNIFLQLEEKTDFRDFDVGNNSAFTEKTNAGNPDVPVVSLQNVSLGWNETDVPVLANINLEVKKGAKIAIVGPVGSGKTLLLKGIIGEVHKTHGRLSLSSSTSLSYCSQKPWLENISAKKNLTQYGNEAYDSEFYRQLASDCMLDDITQLPTFSSGAIGTGGVMLSGGQRQRLALARALSTKSGLLIIDDGFSALDRKTCRHVSEMLFNRTLNPANADRTIIYSTHDEKIARLADEIYRVDEAGHLSRISLDAIDDEDHVSRDGPSGSLDIVEAAEPEASSSAANTALKPHFTENSENTSEEEDEQPRVAMAHKLLGDGAVFKAYFKSVGWVHSAFFMIGAISWAVSFKFSDIWIQWWTDAVDTGDSSHPLGYWLGVYAGLGVIALFVLTAWLYHQQFNIVSKSGANLHSKLATTVFKAQFPVISRIDTGTTLNRFSQDLMLVDMQLPLDLFNTASEFFTALIQVALIASASSWPAFGVVPAMLALLYAVQHFYLRTSKQLRLHELEAKAALVTKISETGSGDGLSTIRAHGPVWVDKTRNTFDDKMDRSQEPLYLLYAVQRWLQLVLNLSVAGLVVVVLGTSVAMKSSTKSNISPGAVGVAFLNAVTFGETITQFVTAWTGLETSLGAIARISLFQRQTPKEDTDAVDNLLPSSSARQEPQAIQGPEFGTIRFENVWATYDDVVAGDVDPATVQEESARPRPGQHWSLRGITLDVRAGERVAICGKTGSGKSTMHLALLRMVNIPVGSVFVNGVSHTNMSLETLRKSFYIISQDTPHLSFDTLRQWIDPHVAFSDERLVQVLRECGVLDMVMNTPGRLAASKGDFKFSVGEEQLLSVARVILDVERREGAQGGENGGIVLLDEATSSVDKDTEEKIEKLIKTRLGGKTLIAINHRLEAVMDYDRALVLDNGMVVDCGTPAELVRRCELFAGLKANTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGF9</accession>
    <name>A0ABR3ZGF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6536 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046623">
        <property type="entry name" value="DUF6536"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395:SF1">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20163">
        <property type="entry name" value="DUF6536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="575"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="715"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="766"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="838"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="881"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6536" evidence="3">
        <location>
            <begin position="217"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1032" mass="110843" checksum="A2697F9C67B8C0CC" modified="2025-10-08" version="1">MEVTIPPRDHLDRDEKYSWDDDNFRPVPRNKPRLTRQTVQWPFQSISLEDNTYALPPIPQSPSSTITSPEEVHLPPRSRATWQPRRGVAHGYGYGDSDDEDDESDKKSTLRRSLIPDYVINYLRGETPETLAQRKIERQREEESQSQENLVGGAGGLRGGGSRNSHVDGLPMPSPGYRRSDEPMLIGNEYNEKRRSYGTTGQRRRPNKRRGLVAHGWRAGVALHGVLALIIFVVGLSGLVVALTVLHRDGGRMSMATLFTSHAVPVTDAGSASCSGAHPVAWLLRAILALFSVALLAGAQYVFQILSSPTRAELDAAHSARRWLDIGVPSLRNIVFLLGQRKARAVLALVAVAVAVASTVLYGALINVVLVAPLSAAATPSYSVLLVAPSFLDGSPFSNASSNNAGGLDRVTILQLQQLAANSKQQTLKNLTAAECLQAQSSASTMSTVQKELTLFNINDDSNNSSSSISTTDFSAVLIVLTDDAVDSLQIINSSVVQTAPAGSELLAADASLGSSSVFQITNDDSEGIDRSAFVIDESAVAFCLVQETAITTTAESADDNTATTTCNVTLNTTVLSAIVGLNVVTVLSFAYLLLPRKAHRHFRQAPLITLGDAVASFLRDPDPTTRGACLLSKTDVVQHGVWKSMVDVPQLPGFGPYQPRQSTESNGTGQSAQQPENVMQPMFLEAPADENSMGISGSGSSNYFWFQSVSLTRWFAGAATWWVVVGLALAAIVVTVSSNNSLGSFGQISPLSSAVYGTSSTSTSWMTPTALLGSLPQLSVAILYLFVDTHLSAYFLSHESAQYVAAHQHQRNEQLQQHCRRPLRVSYRPRGHQTTSLYLTLPQPWHWTLVVMITGLIFALGESVVTTGVTSTDNETQVALLGFSGVSLIVVLVLLAGLALLVVVLGARRTPPPNASLGRNPLILPGGSCSAVISARCHPIPEEMPAELTGLNGSNGGPLPLWLRPLAWGPVPAYHHPYQGYNRRRGLTREGVLRSDGTVGSVDEDNIDAIVGHCTFSSGPLMPLDTARSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGW8</accession>
    <name>A0ABR3ZGW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002959</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="573"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="597"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="746" mass="82189" checksum="A2E1B543BA1A6EAD" modified="2025-10-08" version="1">MVGVPGRSKGCNTCIQRKVKCDGGQPACGNCRKSNRLCTGYKRPVAFVMSSNVTMGPEPIEDTEGGTITTQGRWRKRVRKTPKALAQDPKPKQPQEPTSSLAAAAVAELAESSSIAASRSQGGMPRAIDAFDLSTTASRADIKRYWKQFIYHDTDDEEEGAQGENQQNFNTKLRQQQLVPTRRAPMTVETLSKVISMLESSANIAMLDFTSPLSLSNSAAAATSHDVSMTGMDGWPIGSPFIHHVSTEAAWREQLFPMFLSFHLPTELISGCKTTTKTLRSRNWLLNLSDTSLDNAPALESGMTALCMARVGRRSNNMALVQHSLRLYTKGLHQLQDAIHDPATQLADQTLAACMAFSMYEVAECPSRHLNGYYSHHTGGLALLKMRGPDAHITPLGHSLFVFMRLQQFIYALLMRKANFLCEPEWTNRPWQTAAKDPQDKFMDQMYCIPVLLEQTDKLSEAQKTIGVEAVIRGFWDIIGQYHTIYRCLMGWHKDLQAIVAGPLYWPELSTIECPVFDNTSRGRPFAVAFHFPAFAIGQSVVLFWVISMMINHQIHWLYGRITELQSSPGYMSTVPQAPKHGTDPLTGASFTANNWSEPTSPASSQSTAPDASPLGSSSSPGSADSPASAPAEEPSPHGEFPPSAAAMKAAADDALSILRTVSNNICQSIEYFLDDKMGDVGPLSMILPLTTLRFVMSRMPPTKPCPPSPFPNRPNEYSDEVMWADFLIKYIGARGQQLAYYLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHC1</accession>
    <name>A0ABR3ZHC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosylmethionine-dependent methyltransferase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="868"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="943" mass="102363" checksum="030599CC4EA31CCD" modified="2025-10-08" version="1">MQQQQQQQQQQYPPALAPGLAKSSSTKLPSNVASPGGNSSTLGFDGQQPHTPLLTKQTNLEYLEQVSRSQSQRYPTQTGPLQTHQHYSSSSLGAASVDDLSRTLPISSPLVGQPPQFPLKDQYQQQAQQAQQQQQQQRVQSPPQPPPPAQEPRRTTRKLFKNFLGGGSGSNRGSDSNGRSHQQQQQPPPPPLPQPGPPPASQNIHNNSAGLARRPSKRLSQQPISLRTGNSQVSPDPSQQGWPIQGQQQQHFIGTDPAGNPNNTQPSPLQGIGEFVDNQGGGYPVSDNDQPPSIRRVHTGELDQQQNSPYGPDDIGRQNAQLAQGGYIQQLPPGVSPSDQLLLQQQGGNAAYGQGQFDPQQQQQYPALQYQQQPQAISTNNPHHGFIGHLNTAGLQQQQHSLLQQHAPNPETISQVSHESPVADADQLTTQISSSAGNTYSPQEPQRQIPQGQPAALQDLAPTPPPPAQHPQQQPPTQLQVGQAPQQQGQEPQNTAQPGQDLLQEQDTMPPQPGGPPPNRRSQDTSDRAGQGPGQPPPYRHNQGAPSASGPPGSLSPLPPLPAGSSGTTGGPTQGGYRNAGDQRQYEGASTEGRNSPQPSTNERDAAVPDPEKALKELALKYKNVKRLYFEGKSQIDQLTGQIEHLQNAIANQRMSQSRTALDDSEYATRFNRLNGAINNLSFNIRKDWVGLPQWIEPYASPDALKTGKQEMTAVGRAIICRWVVEYIFNRCFHPGLDPELSQQLKEIERNIRGSSKKFSSQEEFDALTYKIISWRMATLEGLQETLSRPESNENRLKFTSQAIADLTKYLYQYMSDTPPGGVDGSASMIVELAVGIASNLPMESRDVVVTLPLPLEYVSPQWMDVEKGALPPLNTGPADDGGDEDEDDDLSDAGTAGNDDEPGGKTRSGHPSNDMPKVRFAGFVAVEVRGRQVLAKASVWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIJ5</accession>
    <name>A0ABR3ZIJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="747"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="865"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1302" mass="143907" checksum="955E4969ADCF9234" modified="2025-10-08" version="1">MRPPPATAPATAATDDGESPPSSRPSSSSHQLLFKKHKVLPHPRKDASYASLRGPRSLATSKKAGLALANSVASSAVGGQSDDASIISSQQSSPRTKKQYPKTLGNGPDLPPTPPAHSRNSSATYSALPSSATYVQSPERSAEDIQLKPALPTTPTKQLSPPTPDVTPPHVIQHDLRPKGPAVRPPLRDRNMSKSTADSRTASFKTARENPSSSSSDNEDSFASLRPAPISERTSESTVRHLVAEKDETPKKRQPKVVGLGLGLESSPEESITPKSKREFVSFDGEWGSSSEDVGQEWDDNLQRNVAVRHRRTSNRDATGPLPRNEVIEDVTVTPTNATKALRTMSLPQRILTFPSPNESIDQPKTQPQAQRSVQQQQPPTQQPQRQQRQHKRQQSQSQQQRLPVEQNREQPLASAAPIVAQMAPATSLSTNDRGARVSTASASSKSTVSAVVEAVLVGTPPQRQRTLRHVKKQVTLRDSGLDLSPATSSAATSLVDETTRQRRPNGGRFNSNGHDSIVSTTSMNSVSSRSARREIWKAGGIPVIVVPSRLSSVRSTSREPSLRSTSSRRSKRSQSLHSAPLSQFSKSREVSPYIDQRSRRSRAYSESEGSTRNSFARDGSAPGDQRTIDFPPTIPKRSSSLSAPTSRNVSRSGSLTAESVHAHSAILRARLKDQEKAQPGAEFNVRDPSPAAKPAQQVEHAVEPEQPTAKNEVFANQDAQRSESLLLRDTRIERNSATEQQTVLHRPADKREERHEDAQKNDLDNIHGDDNNYDHPNHLDPRSSLDRHVDRYSSRHLSPHNTPFSMVSVETTTTHHSHAEVSEALAVNIYPHQNTSVLVVDHSNRPSDCSDDSQPDRLTDDTGPSSSKQESSPASEFASALTPSSVSAPPPDRPRITKTDHDAAEDMPVTPSHQQLFSLDDVDSPLRNPRAPPVPPAINFIPATPSGLTPATEQERNMGNYFEEAGVTDGRPRRRRSVSVVLRNALGRGRSTARTDYGPSASRSGGLLTRTLSLTRDASRRAFAVRRSESVDRRRSIDFDMDRPAEEDKLHPFWRPASQQMDDYDDDDDYHHDYDEDETYRYPPIDNRPRAPRRSLSMRMKRTFAILPVNRADDFYPATGDETLDRRTVRRTPSGNLRVVKHHGSTESLGEYSAPGIQRPYTAPERHGSRKFKFWRSPSLSRKKRYELSDSNNYYSHTGADDYTNAAPTTNNNLAHEDEVTGAAAGEERRPMKILPNLGLGDKIGEYGPHTIPRRFIERRREKRSNELRQKISGPQEVRDGVGEVIRRTNYRDAFTQAQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIQ3</accession>
    <name>A0ABR3ZIQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="17"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="583" mass="63215" checksum="3AD4F7DF615CAF82" modified="2025-10-08" version="1">MTAASGVTHVHRGRSAPRSRNGCWTCRGKAAKKRCDEQRPVCGRCQRGGLVCDYTPRPKARTTSRTRQRAASTSPGASPSVSASPTSSAPDFFDLPLIATSNSSLALTSSDHEALRYFRTTFAQYHHTKHPQYGCISIMFGLARDSAMVMHMALALGFHEMDVRRQRRKGAAAPLRLEAIEAASSSNTTTAVNDSRPTQHYAAALHMLASVVGNSTSPSLTMGTPETNLEACLSTLWLMLLYEQQFGDPHGRGMAHHLRGAALLAQHKVVATSAPLSLYTVRMLIWIAHIDAAAAAVGLGGFFDRALISDLLAATQRVGETDEGGANVAQTEIETAAAAVPDFVGDDDNTVDLLVRMHRYSNPLYRVTWASAYPQVELLDDLANRSVFHLFTCCGPLRRMIANLSSLDPSGDDFDRERETIGRAITKVRSAFGEVLDVARALSIDSNGDGNAGQPRGLVANLRIVVPTFYAVEIEYARVAGNITTKVATALGEILRLAFQAHRQGGDAALTRIAWPLFVVALETTDLLHRKWVLERFAGMSVLGDHLQRAHRLLSDAVSLQERTGQRADVKAMMPSYGAIVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJC2</accession>
    <name>A0ABR3ZJC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Prenylcysteine lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036292">
        <property type="entry name" value="Prenylcysteine_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011818" description="Prenylcysteine lyase domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Prenylcysteine lyase" evidence="10">
        <location>
            <begin position="141"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="576" mass="62395" checksum="648BCFEBBF7240E8" modified="2025-10-08" version="1">MKLSTLFIAAAGLLTAAAASESYDSSDSSKPRRIAIIGAGAAGASTAYHLRQFADQDGVAVNITLFEKTDRIGGRTLTAHAYDDPNQPVELGASIFVEVNAILWNAASEFSLPLIPAGGNDDDGGLLGIWDGDRFVYTQDDRSYGWWNLVKLFWNYGSAPYRANKLMQATIRRFLSLYEAPYFPFRSLTTRAYELELTYVTSQTGAQFLEANKVSDAFSHDIVQASTRVNYASNLARIHGLDAMVALAPAGASQIRGGNWQIFDRMARASGADIHLNTSVASIDCVDGTEPPNSKYVLKTTNAAGVAEEDEYDNIVVATPYQFSKISTGDGVLQTAIDEIPYVQLHVTLFASPLRPSPAFFGLEPGTPVPTTVLTTLADDDDDQGSSGADGSGKAGFFSVSTLRRAINPDTLREEYLYKIFSPEKVTPEFLSKLFGVEVPESFTSTEPKAREENESETTSESEADASSSVPVISWYFPHVFHSYPKAYPRVTFQDPVVGDGLYYTSGIESFISTMETSALMGKNVARLIVDDIQGLTTGEAVPEGWEAAKESTTTKDGKKIAGLRPDHGQQVVGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKG6</accession>
    <name>A0ABR3ZKG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-mRNA-splicing factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PRP8_1</name>
        <name evidence="2" type="ORF">Sste5346_002369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012984">
        <property type="entry name" value="PROCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="1">
        <location>
            <begin position="514"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="749" mass="85321" checksum="8A6FD59C40CC79AA" modified="2025-10-08" version="1">MDLCQVFDQELESLGIESVQKETIHPRKSYKMNSSCADIQLFPNQRWNVTRPSLLFDSKDTLEATTTDKFWIDVQLRYGDYDSHDIERYVRAKYLDYTTDSMSLYPSPTGLMIGIDMAYNLYSAYGQYFPGLKILIQQAMAKIIKANPALYVLRERIRKGLQLYASESNQEFLNSQNYSELFSNQTQLFIDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQLIVTRKGLLDPLEVNLLDFPNISIRASELQLPFQAAMKVEKLGDMILRATEPQMVLFNLYDEWLKSGISSYTAFSRLVLILRALHVNQDKTKLVLRPDKTIITQDHHIWPTLTDEEWIKVETQLRDLILNDYGKKNNVNVSSLTNSEVRDIILGMEISAPSMQRQQAAEIEKQQQEQQQLMATTTKTHNIHGEEMIVTTTSQFETQTFASKTEWRTRAIATSNLRTRSNNIYVSPADSDSGAITFVMPNNILKKFITIADLRVQVAGYLYGSSPPETDQVKEIRCIVLVPQIGGLRGVQLPDQLPQHEYLKGLEPLGIIHTVSGNELPYMSSADVTEMARLQDQHESWSVNRDSNVSVSVSFTPGSVSLSAWGLSPQGFSWGVQNKDTQSDQPQGFTTSMGEKRKLLLSPKYKGFFLVPENGRWNYSFMGSDFAGLAKKSVHVKLDTPQPFYSDQHRPLHFQNFAELEDIWVDRDDSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKJ7</accession>
    <name>A0ABR3ZKJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32568" checksum="200EB46F8FD534C8" modified="2025-10-08" version="1">MDVAASIAGIVSLGIQVTQSLVDYYTAYNSREADVAYTAKKLNRLLDMLKNLCSLFGDRKFLPDEQDLLKTIESAIQDCKECIDELQSQWRKFKDNSTSGIRAKARTAARKLEYPFRRSTLEALDEAVNEIAFHLSLALQILQQDTIDRVQNDTEEIKTMLELVRANQISSDIHETYERMLFNISGESKEGADVNAQGGRYGNALQAASAGGHEKILQLLLGKGVDVNTQGGFYGNALQAASAGGHEKILQLLLGKGVDVNTQGGFYGNALQAASVEGHEKIVQLLLGKGADAKARSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKX1</accession>
    <name>A0ABR3ZKX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="144" mass="15671" checksum="580260E38AF3581D" modified="2025-10-08" version="1">MAADIPTDGISLRFKSGPVTTFLFVDRSATFTSIGNRLLDALRERYPHGLPETAMLPDTTPLPAAGEGDARVVFGVPRNPRDLSVGWKPLNTDNGETPTSLRLRENSVLAFTIQSGDSIGGTPSFHVEIPTFEEEQLGEEDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL01</accession>
    <name>A0ABR3ZL01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="56"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="468" mass="52925" checksum="F7252592236DC532" modified="2025-10-08" version="1">MSLAACMSPSRAAHGSSDGAFGKPGSMAGIGRLPPTSIPAGAVYETKTINFTTTTRTVLDRTPVEVLVEVFQHLDIASAFSLAATNKRFSNIFAANRTSIVLCIAQEEFSPFDGLLQVVKASPADLTIPWGTWLDKRIRRQNAVLCPGGTLPKHCPGHTAAMKISCVEARVEHSDIDRILSACRTVRGWERIFPQHRFNASPVMTRSLTERENFRLRRALYHWMRYAYYFHGDLTRPNLFVPSGRDIRINQLRALSNSELGELKDLWRTVEDIIELTMCPSIANVRIGAVRYSRNMLYLLGIAVSNIYQDFELSEKDAARIGWGEQRENRTVVSTMCKLSPEELLHYMENGHKFTKLRLIQDIRQRHPHFEFDTESLTLALNCVIHERWRRMQTEFPAITQPSSGVLCLPVYTRMMGQCHGGILDWDDPATEAECTRVGEMIGLGLDWRPEESFFRSKPEIPTGLLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLG5</accession>
    <name>A0ABR3ZLG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31261" checksum="D0AF7E9B703CF760" modified="2025-10-08" version="1">MHAIDIIPRGPVAAELLFYQPPKDGSAPYDYVGKAPDGDVQQNFSEAPKTVEIDDIRGREEGFNIDADGFQAISDDIHGDSPVVDFLDEESIKSKYYAEVKELIRQQIPCVTKVTIFDHTIRRSAPGAKRGPVTAVHVDQTARSGPWRVELHDHDDAQELLKGRVRIINVWRPLNGPVRGFHLAIASRKTVAIDDLVPVEHRYPDRIGETAAVRHNPNQQFYYWSGMANDERLFIKCYDSNDGEGPQGVPHAAFIDSRATEKERYRESIEVRTIVYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN73</accession>
    <name>A0ABR3ZN73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">COQ4</name>
        <name evidence="9" type="ORF">Sste5346_001933</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid into 2-methoxy-6-(all-trans-polyprenyl)phenol during ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H(+) = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:81179"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="4.1.1.130"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the COQ4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03111">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007715">
        <property type="entry name" value="Coq4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027540">
        <property type="entry name" value="Coq4_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05019">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1 7" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="265"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00081568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="301" mass="33604" checksum="28AE8166403CEAAA" modified="2025-10-08" version="1">MRSVRLISSRKLAQLARPSIFLPAGAEASVAQHIRAFSVLNRPPPQYDGHVPLTLIEKGAMTLGSAIGAFIDPRRADLIATLGEVSAGPVAQRLRDTMLSDPTGRQILRDRPRITSESWPLDELLAMPHNTVGYVYGHFRKRYHMSPDVRDEVRYVDDAECAYVIQRYRECHDLYHAVLGLPPQYVEGEIALKAFEFVNTGLPMAALSLVAVARLKPAERQRFFSIFLPWALRSARRAKPIINVYWEKELMTDAAELRERLGLEKPPNLHTLRKKPKKEKPVAAEASAATTATPAESAPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP64</accession>
    <name>A0ABR3ZP64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Sste5346_001235</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 16" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 16" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="931"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1204"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1603"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1628"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1653"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="20">
        <location>
            <begin position="1"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="19">
        <location>
            <begin position="955"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="21">
        <location>
            <begin position="1827"/>
            <end position="1882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="585"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="105"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1902259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1891" mass="208922" checksum="5E730755035E6758" modified="2025-10-08" version="1">MALNLPPLGGGAGGAHTQPSLPSLPAHLQSDTHLTAHLASRFHVSLPTARLSSHALISLNTYSSSSKGVDGGKEGSAHAEAEDMADRAFLRLGHRSENQAILFLGESGSGKTTIRAHLLAALLNKSSTPLSNKVSLAAYVFDSLTTTKTATTPTASKAGLFYELQYDTASSTAPLLLGAKLLDHRLERSRIADVPTGERNFHILYYLMAGTSAAEKTHLGFDEPHGGSQRRWKYLGHPTQLKVGINDAEGFQLFKTALRKLEFPRSEIAEICQVLASILHIGQLEFESTNDTTPTADDSGGFSHEGGQTVIGVKNKEVLSIIAAFLGVSAADLQTTLGYKTKMIHKERVTVMLDPAGARSNADELARTLYSLLVAYVIETINQKLCAAEDAIANTVSIIDFPGFSQQSSTGSALDQLLNNAATESLYNMTLQNFFDRKADLLESEEVSVAATSYFDNSDAVKGLLKPGNGLLSILDDQTRRHRTDMQLLESFRKRFEGKNPAIAISSATAKLPGSNFLSENMAASFTVKHFAGEVEYPVKGLVEENGEVISGDLLNLINSTKSEFVARLFGQEALQTIVHPQERSTVMQASVSSKPMRAPSVMSRKGGRAGAARRRQDTIQRKESLEDIASDAGGGTSAAGDARRSNTKASAEQGASGQFLTSLDNVTKSFNAPNTNAYFVFCLKPNDRRIANQFDSKCVRTQIQTFGIAEISQRLRSADFSLFLPFGEFLGLTDAETLLVGSEREKVESVVEEKRWPSNEIQIGATGVFVSERCWMEISHFGDAASHSARYGVPSDGGYGGMTPLDPFGASKERLVSNSNTPSAAGISDKARAGYFGSNDVDARSEAGVSAFGAGDMFQNLDTREQMAERGNEKALVEVEEYRDSSKRKRWVFIVYLLTFFVPDFMIRYIGRMPRKDVRMAWREKLAINFIIWFSCAFCAFFLVVFPRLICPTQHVYSAAELSSNDGKSGANSFVAIRGQVFDLGSFLPHHYPSYLPDKMLTQYAGEDITALFPVQVSALCQGTTDAGINPEVTLDFKSTNTSGSVTTISNTDLNAGYHDFRYFTNDSRPDWFSEMMIMMRSSYKKGNIGYTSSYVTKLASGGKSVAILNGRIYDMTNYIANGRQLIAPAGDDVSGTADDVNFMDQLVVDLFQQKAGDDVTKYWNALALTSTEKSRMMLCLDNLFYEGDVDTRNSPRCLFAEYFVLAVSILLASVIGFKFLAALQFGTKNMPENLDKFIMCQIPAYTEDEESLRRAIDSVARMRYDDKRKLLVIICDGMIIGQGNDRPTPRIVLDILGVSETVDPEPLSFESLGEGMKQHNMGKVYSGLYEVQGHIVPFLVIVKVGKPSEVSRPGNRGKRDSQMILMRFLNRVHYNLAMSPLELEMYHQIRNIIGVNPTFYEFLLQIDADTVVAPDSGTRFVSAFLDDTRLIAVCGETALTNAKASFVTMIQVYEYYISHNLSKAFESLFGSVTCLPGCFSMYRIRAAETGKPLFVSREIVDNYSTIRVDTLHMKNLLHLGEDRFLTTLLLKHHNKYKTKYINRAHAWTIAPDSWKVFLSQRRRWINSTVHNLMELMPMAQLCGFCCFSMRFIVLVDLLSTVIQPVTLAYIVYLIVLVATKGTVVPITAFILLGVIYGLQAIIFILHRKWEMIGWMLMYVLAIPIFSFGLPLYSFWHMDDFNWGNTRVVAGEKGKKVVISDEGKFDPSSIPRKKWEEYQGELWDAQTARDDAHSEISGYSYATKPNMGGPGGVNVAVSEYGYPSRPGSTTGYPMYDKSAPPMPNMANNMSRMSFMSEQPGGNRMSQFGGSQFLGGGEMEMANLVGMPSDDALLAEIREILRTADLMTVTKKGIKLELERRFNVNLDPRRAYINSGMYHLFLTMNLDKSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP72</accession>
    <name>A0ABR3ZP72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="65"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="730" mass="81457" checksum="6FD4501608606FD6" modified="2025-10-08" version="1">MAEPTSTPAETAPTTPVASGTGVYIPIKSDFEIRLLELLPSTADDDDDIVRVELHSARLDKLLSFEAISYCWGDPTDVMPILCNGEPLDITVSLYGALRRFRPRAGEPKRTLWADAICIQQTNLAEKASQVMHMPHVYSRADRVLVWLGEDNNDPWVAKVPDNLKEALGFLPDTPLDTEGVHKTTRHVYSEAQELQRQGKPNFLDHDWSPIVRLVERPWFRRKWIVQEVCLAQDILVACGRVTFPWAHLAEVAYNTMAAGILQVILGNTSLVQHLPLFQKPGILTDDDKEGSSMSNLTSLVFQNIQIMRMIRTFRHVGNLLDCIMATPLFECTDPRDHIYAVLSLPVYPTSHQLRPNYTLTTEQVLTAFAVATLVGEQNLKLLGLCPQLSRPRRIAIPRRSPALPPVPAEGLLPGQPIESEHFIEGAGSILDPTMDSVFTRADPLDLPSWVPNLTGMGIINPFTCYSVLPQLFHAGGPITPPVSVSGDNSLLYLQAKVVDTLATVLPRGIKYKLPSDDDIAPYLNRFDDNQGLARTQMWHRNWLLACKNFLLDVDINSPASLPMTPEQWLTFAKIMTCEQNNRRDSMPPAVYEAFDEYVLHILGVFEDDTKAVDEAAAANIELMMIQFGVMIESSVLTMSSMRLLGRTASGRLCQVPIDAEIGDSIVVVIGAETPFVMRQDEEPVDKLKNDSWQPGEKRFKLVGDCYVSGIMQGEILDDPQYETRQITVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPD3</accession>
    <name>A0ABR3ZPD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="315" mass="35255" checksum="9FC165B90E55A7C2" modified="2025-10-08" version="1">MNDEPSGCSNYDGPTGAKETFVDGRVVVLDVDHLSWARYLEKKDLKAQTNKKSSKRAAHNKPDVHTKAQIASFCSSLAVLKNEKTTAGDCPSRLEDGRRKALQEGLLDEENQKSAVIFTEYLPKSDDYKDTEYVADAYRTAATVFQRRLVPIYLTCSPEEHQRRIECRLRDELGLVKQARAGGAVFPKNQMTAMTPGEVEKAARSLDKQNRSGSELYTFSAPAKFSNGRFTYTEPDSIDGPALPKEHHGLCIDTTGLTPQETAVVIRDFIYDVLSGESNRITKIYPTTCEEGERLHEEEKESWIIVNEADWTGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPK7</accession>
    <name>A0ABR3ZPK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hamartin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="893"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="660"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="758"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="861"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="545"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="575"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="960"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="979"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1055" mass="117782" checksum="39760B5FD040EBDA" modified="2025-10-08" version="1">MASSGSTRDLHKAIQASLVAPKLPLSDGLIRILDAYLDKHAEHDQATSDRLQEDLLATFNQSVHNKQSIHYAVFLAILRQLRPAIRSTAHLLQWWEKLIEPVFDHLGDERGVSGEVLSDIGEFLFPDDEDDDNDEGNGGAQDTNKEAAPYALGLRLLQKWMDVYHVVLAGGYSSHWTKERPIQEVLVLFGKKKPKEFFPVLNDFFVQKFYRTRSISLLSEFIRSQPPHLYLIIKSPLFESLLRCLQMDTSTTVVSLALTCLTMLLPNMPGSIVPYLPTLFNIYARILFWDREQPITDDLGAAMASPSEQNSSFQAWEKCTFSPDIDSIAIPHLLGYFNILYGLYPLNFMDYIRKPQRYLRHANASDTDDIEIQPSEIRDRSEKYRQSHMLHPNFYSLTIESEKTDFGRWMKSATADVVAECVSLHISVSEIHALRNDSITQRNLLRDQFPSLSNRSSALPTASDSVEEETAPDRIPSSARLSASTGISLSVSSRDPATIMRRTSQSSQPSDILRRDSTTDSPTLGPLLSQTTSRTDVQDGDSSRAAKSSLYQSQANDSVQSLSLSHQESVPERLTSPSKVSLRQPSLSAPSPLHHLDTAADVDSDKAVESNENTMTEMRRQILLQKSDLTFERYMVQQHLAHIGALRRSNVRQAVTEAETQRLILANRTLKQRLEEAKKTEAQVKKEAEMSRNMSRNWGDSLANKLKKLREEHKAWTAEEETLRRDLKVSQEDGARLLALVCSAEVRELKAKQDMQMLESAAAETNKLKEEVKTLEAAKRESQKLETQLEQTREEASKLEGTLELLKMKLEAREADLARTRTYYQHQVVALNAKLNEALGEATSGNGVNLSETRSQVDNALAASRAKYLELQKKHARLMRRYTLLESKRLEFSTSPPYDEPNYTSPRGGDIQAAALSDPEMDNSGMCRSQPIAMRGSVSSVGSGTNRHRQRVASDAGSFDATSPGTWAVQMSTSIGSAVSSPSTVVRRPSTPSGPTPPGEAPGSTSPQAERYYGRGGVQNSLRKERKDSKKSEEPGDKGDKKPTGSGIRGIRGFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPM4</accession>
    <name>A0ABR3ZPM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC36</name>
        <name evidence="6" type="ORF">Sste5346_001085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="465"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="594" mass="60971" checksum="FDAAD73BEE3B9B1F" modified="2025-10-08" version="1">MAGGVPHSLRGVPNGFNAQQQQPPQQARSVSSRLPNGKMGGGNNSSSNNNNASGWAFGSGVPLAGSGGGGGGGAGLGGGAAGGNGLQQNQGRPQQQMGGNISFAQSLGGSQPATPLDLSEFPSLSSGSQLANAGQASLWSTAGSRSIGGGQAIQRGANTPQQQGGQQEDMFGASAARLQQQQQQQQQQQSNQGSFRFGSQTASIGQANIGQQSSIGQASIGQQQQQQQQAAQSSQPGSIDDFPPLNRSANAGEIGQDRTASLMSSLGYGSQASATSPAPPGIGGTAGAGGASAARGMGNGLLNALSANSGSRVASGGSSGAPGGEVRSPVGTRPAQETTRSLAVEEEAAAARQKQQESDAASAAAAASAAQSPIGEADGRSSIGAIGGGGDAAGNLREESEAAANASQDPLAGTAPIDRWGMKGLRTLLNNPEYSAMISGWGLDLNTLGVDLNSNDLLSTQTYSLFDGVAPRPAVPKFRLPECYKVSNVGPIESKISSFNEETLMWIFYSCPNDVKQQLAANELNNRNWRWHKRQQVWLTKDDLMMPQVLSMNHERGFYIVWDTTTWRKERTTREITLNYGDLDNSPVATGGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ76</accession>
    <name>A0ABR3ZQ76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="601"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="738"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="827"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="906"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="925"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1215"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1245"/>
            <end position="1264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1298" mass="136858" checksum="FB4C639FD8371371" modified="2025-10-08" version="1">MAAEINESTPVEAPAISEPEPQASKNNDLHNGGSNPPSVNGTATSGSPDELSNKHIADIVDDLVNSAEPSISGGSDTETSRVDGAKNKDGDDKGHVRTSSTARKPTTFKSVSVNKTFLAAKAAGTAGVAKPGDKASPTLAVASLTSASSASARPRLVAKTGLVKGSGANGRPAAAPDPNAVWNKNRPIAPPEPRKLTDEELKKYGIHISTRLQQDDDAKGQANWADIDDDDEDWAPEEITWTDGTKSTIPHHDEMQPSPQPQSLQPDMSRSQSVYHPPSHPHPQPLQPQQHSSALASHPSPIAHPSSLSKEVDTTEKPKSPAPTGVRAGGLPSGRGLILKGAPERPTLVAKPPAPPTPVKSPWASLPPVDKASPVTMDLPPAIGSSRLPYQHSQFHQYPPRDMYGGPPRGATPPPAPFKEIAADDFSRGGFRDSHPYANRELYNSQSGRMEPVTDRRGSMHRGDMHHRQHPSQLLQRGGPDQQPEPSAAFQTHHRSAQEGPYGRRRNSSNVSGGSGGFMQRLGRPHDQHVPPELLHAQQPSLAGRSDSPASPRNYSPSGTRSWQQRGSPAATFASMHSSNPQANAPAGSGPPSAGPPNAGPPVQQGVPPAAAPASIEDELEIQKKIMRERRELAKKRRLEEEEREEAAKRERIRLKLEAMGPAPERKSAKKEPSKDEPASTPTTTSAVPVTPVQANAQLSSPGGDATTDGGGQDNSRPPQPAATRADGSANPDAPHGQSQQQPQSWQSPAPPQTERIASWGSSNQSARNVWGSPNNRSLGNGTFTSDLGPIGPPSAQKNNAAAPSIAPIGPPKSTVVLPPPPPPPAAVQRPAPRSAVAQQATGGAGGSSAEVARSAWASAVKASDETHFAQQKAHRAEQQREAEARGLGLKDIRPTIKDTWLPTRMSEDGNRVEDRSNQSVVHRPGTTVGGSSSPGSTIHSSRPSRFFPTRDVRLEDAVAAAQESAPGGTSTIGRNSHERPGSPSPPPPDMDGHPAFDGDAAHPHVSLPRPQIVVRLPPKDGAASAAADHTTAAGSHAKNAQSRNATSHAHDSQPTPTDGASWQAKFNNLFDRKPAAAPPAKPAGRPDFQNRNNNSSSNTENVHPASSRAAPPRNVKPAPKEPFTTRLMAEDCFERQEMGSLPPVHLPNKVPELAWTPAAVPKPLARRFLIATATSGDHEGFLKDYFGVPHTVSIHFPGMAGSGKSVNLPTPRTNSNSRRSNNYGRSGSGRSHRGGGNKNRDASSTHSGSHGNNDKTTPPSTRQGSSSGRSRGGGGGSSSMRHRSENWSRGTPAPVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQJ3</accession>
    <name>A0ABR3ZQJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">CLP1</name>
        <name evidence="14" type="ORF">Sste5346_001425</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Polynucleotide 5'-kinase involved in rRNA processing.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Clp1 family. Clp1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051734">
        <property type="term" value="F:ATP-dependent polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1030">
        <property type="entry name" value="Clp1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.330">
        <property type="entry name" value="Pre-mRNA cleavage complex subunit Clp1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03035">
        <property type="entry name" value="Clp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028606">
        <property type="entry name" value="Clp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010655">
        <property type="entry name" value="Clp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038238">
        <property type="entry name" value="Clp1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032324">
        <property type="entry name" value="Clp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038239">
        <property type="entry name" value="Clp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF6">
        <property type="entry name" value="POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06807">
        <property type="entry name" value="Clp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16573">
        <property type="entry name" value="CLP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 N-terminal" evidence="12">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 P-loop" evidence="13">
        <location>
            <begin position="187"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 C-terminal" evidence="11">
        <location>
            <begin position="398"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="161"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="144"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="530" mass="56233" checksum="37993B329C6EDAD7" modified="2025-10-08" version="1">MSIPGLGQIPVQTTVATTRTYKLAPLSEWRFGVSQPAIKVRVLSGTAERDGTELATSQTYSFAGTQSKILTWHGCELEVEGACDHDEVVPGGVKGDAGSGALSPMISYMNLHLLLASQRATAASMRRGSPGAAGPRLLVCGPPHSGRTSLVRTLTAWATKMASFTPPPPPPPNPYQQQPPPPPPPQHQQPCVVNVDPREGMLSLPGTLSAAVFATLMDLETEGGSGWGGAPSSGPSAVPVKLPLVYNYGYAKPSDAPDLYRGLVTRLAGAVASRMSEDAAVENSGLLIDTPAVTADDSSTSNGNGKHSHLMSIDLLSYIIDEFSVNLVVVLGEGAASTAIQQALTNRFQGETTTLGEPIQIVQLDASDGVVDRSDMLEQQQREACIKEYFFGDTKRTLSPYTQQVDADTLTVLRLPPADNAVKVSDEVDGEDGEEPEEGAADEEDAIGEHNLEKVDAGPSLAHWTLAVMNAGLHDPPDVIQHATVLGFVYVAEVDAERRKVRILAPVSGRLGDRPLVFGRWPEPYINLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH7</accession>
    <name>A0ABR3ZSH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000391</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051775">
        <property type="entry name" value="Homeobox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24323">
        <property type="entry name" value="CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24323:SF7">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="57"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="59"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="254"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="378"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="463"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="539"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="677" mass="72214" checksum="82E76F90E8EB5891" modified="2025-10-08" version="1">MESELPATSPAMVARPDGDASNEPLISSPRSSDSSTIDKADESLALSSDAGDQSMLRHPKGKRKRTAAADKSILEAAYLSNPKPDKTARLDIVSRVSLNEKEVQIWFQNRRQNDRRKSRPLSPQEIAALRYGGMHALSSDPMTPFGHASLSQHSSFSSDGHGASSPPHYQQFTSASMPATMPSTTPASSPEIGPWNPDALAQHQQQELAHDRSAASESGAHGAVQTPSGPRSFSSSMSSVGYLANRWNMHSSFSTPSSLSGGNGPSPNGDNSRDESVRLELFVRPSSSAAVLPPPSHQQQLPTQQAQQRPFRLSLSLEGKAEVITGQSPSPPRRLPPPNPTVDIGRRTGSSSSSNGSDNMLPSLPAIRRSGLSRSQSALPSLGLTLPPISSLTNSLESGSAPPPMPQPSHPPRLLRGRSRDVHAWESVCDADTRVDDELSAHAEQEASGSAIAAISLLRSTSSVSNSSMTSNSSVLQPNGHKRNVSSRSGIPRPGMKRAKLGRALSSVARMQNVANTREESGKDKVWVDDEKKKKLKLSTLLSGNDSDKENWSPDEDGRPRHNQLSSSNLGNGSRRPLPSSRNGQQQRSVLGEGGKSNKNAQLATRMTGGKGAAFDAADIYEDGRSPPKRAQLSRAATVSAPDDVEHFMRGAQVSPSKKGDMDCIAGLLSLSQGNWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTC6</accession>
    <name>A0ABR3ZTC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="327"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="388"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="424"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="613"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="699" mass="76811" checksum="686803DF2AE92DA9" modified="2025-10-08" version="1">MDTLLAKLSEQQAAIREQNDGLKRAEESAAFARAMDQQKGSNSLPITPGIDGFQGSSALTVRSSSANQQENDEVLRLKLQLAHAQNKINILDTELANTRSTKPDPSQVLSLANTDPDFPPVPGSDQIAPPGSIGFPAPGAARPLFNRGNIWAQADESRLDTLENSVGSIGRARGMWRDDIKPGGFQQTFPTGPSAIPIGTLSQTSQPASLWPPSRPANQSPFDPNLLGFGDTQAALDDGRGRMTPDTDMLLRPQRPGNRAESRIPVNQDFSGYSNYSAGQMQFEANGGFMPGGGGPNMNSNGLGMFPQFQQPPIGTPLSPHATEFNTDPAPWKSEANTPDNQTFLPTTEPLNYRRLLDLSSNDQQASIFLQQKLKVGTSDQKYDIVEAIAAQAYPLMINRFGNFLVQRCFEHGSPEQIVKIAEAIRGNTLGLSMDPFGCHVVQKAFDSVPESYKAIMVHELLRRIPETVIHRYACHVWQKLFELRWNDSPPQIMKYVNDALSGMWHEVALGETGSLVVQNIFENCLEEDKRPCIEEVLKNIDVVAHGQFGNWCIQHVCEHGAPNDRGRAIDHVIRFAAEYSMDQFASKVVEKCLKIGGADFLGRYLDRVCEGRVDRPRIPLIDIASDQYGNYLIQYILTHASTQHREVVAAHIRKHMVSLRGSKFGSRVGMLCTNPAVATRPGPGVGPSVGRLPPRYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU48</accession>
    <name>A0ABR3ZU48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Poly(A) polymerase</fullName>
            <ecNumber evidence="12">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PAP1</name>
        <name evidence="17" type="ORF">Sste5346_000185</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="16">
        <location>
            <begin position="8"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="15">
        <location>
            <begin position="212"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="14">
        <location>
            <begin position="359"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="441"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="546"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="579"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1903557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="611" mass="68156" checksum="60D6356F64867283" modified="2025-10-08" version="1">MNSEKQYGVTPPLSTEMPTEDQRRSTDALLEELRDQGTFESTAETQKRFDVLSSLRIVADAFVKRVAKEYAPDNPTLSKDAVAKIFTYGSFRLGVYMPGSDIDTLVVAPKYVTRADYFRYFPEMLQTMSPPGAITDLTAVEDAFVPIIKFEYLGISIDLIFSRVLLTQLPADERWGLKDSNLLRGLDDPELRSVNGTRVTDEILSLVPEQRTFRDALRAIKLWAQRRAIYANIMGFPGGVAWAMMVARVCQLYPKATGAVIVSKFFGIILRWPWPNPVLLKPIEDGPLPVRVWNPKVYRGDQFHIMPIITPAYPSMCATYNISQSSLSIIKRELERASETAQRIMAGRQPWKDLFVKHTFFTSDFKYYISVISSSTDKESQNVWSGFVESKVRVLVQGLERHQSISLARAFNKGYERTHFCKTAEEAEAVRNGSLECLKKPEEEGGEAATAAASEANGEDRDGADAETNGDADAFKPTEVFTLTHYIGIELVEGAKALDLSYQVEEFKELCFVWDKYKEKLKNTCTLSIQHVRNFGLPDDVFEAGETKPVKAVRPPRPGARRNASGTSANGARKRNAQEENNAPPSKRQQSQAPVQPQSNGSSTVTAAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUA3</accession>
    <name>A0ABR3ZUA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DBP10</name>
        <name evidence="18" type="ORF">Sste5346_000153</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17959">
        <property type="entry name" value="DEADc_DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012541">
        <property type="entry name" value="DBP10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033517">
        <property type="entry name" value="DDX54/DBP10_DEAD-box_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF8">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08147">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01123">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="154"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="405"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="679"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="871"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="942"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1026"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="714"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="736"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="887"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="948"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1026"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="1043"/>
            <end position="1085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1903525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1085" mass="116112" checksum="629AB2933DC9B230" modified="2025-10-08" version="1">MSARFASPTPSENEVDIMGDLFTDDFGGFGSDPDSDDDNDNDKSSRKRKKAKAAPPPQDDDLDLGAILEGGGFTDASNGLPKKGVLTGANLEDGEDEAYIALQQAAAFRKTSNLKGASSVKGGGFQAMGLNPTLMRAITRKGFSVPTPIQRKTIPLIMGRRDVVGMARTGSGKTAAFVIPMIQRLRAHSVRVGARALIMSPSRELAMQTLKVVNELGRDTDLKTVLLVGGDSLEEQFGLLASNPDIVIATPGRFLHLKVEMNLDLSSIKYVVFDEADRLFEMGFAAQLTEILHALPLSRQTLLFSATLPSSLVEFARAGLQDPSLVRLDIETKISPKLKSAFFSVKGPEKEGALLHLLHDVIKIPLGLPEAAIKARDEIRKNGGDGDGDEDDSNPRKRKRLNSGYVSSKVAPTEHSTIVFASTKHHVEYLASILSEAGFAVSHVYGSLDQTARKIQVENFRHGRTNIMVVTDLAARGIDIPVLANVVNYDFPPQAKVFVHRVGRTARADQEGSSYSLVQDTDAPYLMDLQLFLGRKMLVGRDGVEQASAKGSSKGQYDLTRDIVVGSLARSSVEPHVEWVTTLLGDVHDIELLRQVASKAQKQYFRTRLSASSQSAKRAREMVRSRGWSQLHPIFADSADADGANEDGMDGASVGLAREDLLAKITGYKPQESIFEVHHQNKKAMKSKAAEVMRTMRKRAGPRRSSSGVPIATNDEEDDGADYEEGAAALANGGADSDDDDDENDDAKDAEDPWEDDSEDKDDGADVLENDDAWAINDGEGANGAGGPGASWVDSSVYMSYTPRAGPSMDARAVEERGYGVHGRGGDDDGEGSAYHSFAQAARDATMDLTNDDTAKAFGVPTRSKLRWDKKQGKYVARANDDDGSRAQGGKGGGKMVRGESGVKIAASFQSGRFDRWRKANRLGRLPQVGDAERSGLARQVQNPTAGAGPGGPGGRGGFNAGPGTGRFMHKKELAPKEADKFRDDYHVQKKRVAEARENRVGRFKDGEGSYREVKGMDDIRKARKVMEQKRLKNARPARDGGRGGGRSGGGGGRGGGGGGGGGRGRGGGRGGGGRGGRGGGRGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGX0</accession>
    <name>A0ABR3YGX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chalcone isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000132">
        <property type="protein sequence ID" value="KAL1887270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47284">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47284:SF3">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16035">
        <property type="entry name" value="Chalcone_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone isomerase" evidence="2">
        <location>
            <begin position="168"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="398" mass="43210" checksum="716B1F126355C27D" modified="2025-10-08" version="1">MATAGARPLPTTLSGGHFAKPIQTFQRRTFLRSRDGTVRGSTYDTLNVSKLARDRHDYDRTRLIFLATGSVAGLIAMCFTGWQIKKALEQNPKKLDATGTSSSDIAPRKIIVHDKDGREIVPTGNSTITEFPRTVDLPLKLTGETAQTPAPDAVVVVPPLDGRDGPATEYTLVGLGLRTVTFLKLEVYVVGFYVATADIAALQNRLIKRVNPIATALVSGEKTELRASLVDPTESQVIWDALLEEGIPARSLFRIIPVRDTDFPHLRDGLVRAIKGQSARILDKEKENIGATGNGTAPDFGESIKGFRHIFNRGKAKKGRELLILRGSDGALNVIFDDGRSMGRQLLGCVNDERVSRALWLNYLGGANVASEAARQSIANGMIEFVERPIGTVAAQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH78</accession>
    <name>A0ABR3YH78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARO80</name>
        <name evidence="4" type="ORF">Sste5346_010035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052780">
        <property type="entry name" value="AAA_Catabolism_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR ARO80-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR ARO80-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="64"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="865"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1030" mass="112765" checksum="0719AB431CFF8709" modified="2025-10-08" version="1">MSNFGLPRPSNASLDDSRSQPSQSDRSPSFASSALPARDRDGAATNQQQDPQGQQPAHKRVYQACIPCRRRKVRCDLGSVDNPHDPPCVRCRRESKECYFSATRRKRKTEDDPGIDNDDYIVRNGRRKLHADESSLLEGGAFEEAPIGAGLANVRSHPLRRPQPDDPSSRNGNSGSHKTDSISAADEPNTPLENFEAQTVMRREVYGPHDALDLLYKAATDSPHTKQDDTTNRTSTGSSQNKFAQQPGQGSLRNEYYSGSNAGYGPSRPSRAAPRNEQPVDPELGRRPHPSTLPGYADALKLWARFRFVRAGWFTAQEAIEYIDYYYTYLSPLTPISPPTFSNPATHVTLLTEEPILAVTLLTISSRYKSLVGAGATCRSHAVHEQLWTYLRGMIERVVWGQEAFGGGFCGSGADESQTSSTAPWRGLRKGSLRTLGTIESLMILTEWHPRALHFPPADVTDELLLSANDRDEIMGDDGDSRPTGGVGGKRIDSWLEPAWRSDRMCWMLLSTAMGLAYELGVFDDIDELLASGGITRPEYEEETYRLRAYRIKRLLLIYLSQLAGRLGWTNMVPESLRKKDPVGSRKRPNSSFEGQTPGTNLSSVSNAFNYIPDLELDDQIIHCWAGISNAMHIGNEKLFCSRQHTTEIIQSGKYTELLKDFQPLLRDWWKEFERFKLPTFIRHILSIEYEYVRIYINSLSLQAVVERCTTNATNAGNTAGGSNASGAVPPQLSPQTQNYYGKLPLGRLGGVTAVDQAYVKEVVDGCRNLLRTVVDGLLPGGYLKHAPVRTYFRIISGAMFLLKTFALGAPKADVEISITLMDRTVDALRNCVVDDVHLGTRFADLLETLTSRLRNRFIHAPSMPASANAPHSAGGGSPNAATDLASGTNGHSRGLAGLGQSLASAAMPTNGDQAWAKAGLSGIERVSTPANISATPFDSTAGNFPYPSGTASVLNPSTPAALIGLDNPLGDPVYTDTTDWTSNEMWYLPAGPAFFQNMGDSNVAMTAEGVSVAGMDLLDFMTMDPHAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHC0</accession>
    <name>A0ABR3YHC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat-containing domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000134">
        <property type="protein sequence ID" value="KAL1887233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="445"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="558"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="590"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="614" mass="67207" checksum="16700AD9E964BB5A" modified="2025-10-08" version="1">MTYESHGKYDRAVPLNPNDFPVLRKPEYEWDLVQYRHEETGAIREAVDSDDLPALREMLRLLGPDVLYMCDTDHARSPALHYAIELGRVAVLQMLLDYRDTLTPEERRVRESREEEEEEEKRESCTTRAWDTPLTEACMYARVDVVQLLLERMPDVDVNACDRFGYTPLQVVGRYAQGPPRWTGPDESASRVVIAKMLLAHGAHPDLGGKPHVDGRSGALGNALLQALSSLWGAGDVQLVRFLIDTAGIGVHEGFFHSTARLDGTGINGVADDEGADDYDKPPANERDVYLTPLATAALYRNAAGVKALLDTPGADFTADLTTPSIPPDFRKTGKTTEITQSTGRPPVTTPVPMLPIHAAMVGRPYSILPNAWNFREALEDKCVKATDPAVWEALEVARTAQDAAAHAAYVDACVATVELLTAVAPVCDATINATHTRRVGAHLYQYTPLHLGARFDRLPMLRVLLDRGADPSVPVPHTSHSAFASVFASIHRLCSPQSYMQLGHWASGFPAEETYSAVVQSIDKRIGEGMTALLWDLLGPQAGLADRVNEVNATDRDGNTALHWAMGYSLAYTTEALLALGAQEDAQNLASEVPTEGTLPTTTRGNGHQREYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIP8</accession>
    <name>A0ABR3YIP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="828"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1076" mass="115959" checksum="FDEC4A3D52E8181A" modified="2025-10-08" version="1">MPRFSFPVPGRRKDKQEPAAVQAPPLTKAQKLLGSSQINIDSTTSLTTSDAPRHWDTASNANSSISINVSESALTYDESHDGGLSSLTEDTVVDSPRGGRTAGFDEESGVLPRAFADGDINADFYGQDGRSITDASSLRRKQSSSTIISYYDKSKVPLGISQQTSNSAMAKGLPTKASSLLDIDGSISQASRRKKKPAKLDLSRMFTNRKSSSTMTLNAERGLVLGPDMVTRSPSFMSVSPMDYLNRPHSSHRTSGRMRPSTRGSNREDLSGMASPKQKVLRKKSLPNPRITSTEPVPPTPSTTQEATGLKNLYAHYEQMTFRDVFAEQDAESSSDAPATESEDDHAPPMSPKTVPQIYQEKLEEEARTSGGSYLPQVTREVPLYKDISAYLGGYGANVDVAQRGNDPLDLPTLNAPSGDCSDSISSRHTRTSKASKRTAPSLLEIDLQQTSVLSLSSDSEDDFVDSRPKTSSTSALPSPRSQRDTVISPGSGHRPTTSRSLSSGKKKDRSSGRSDNTVHFLPVPGPNEGPSSGRILPATAYSRASSASASTNSTTKPSIRDARSPSRESRVSMLSTQTTNSVSPANYTVHEARAITLIPAQGASYNTDMTRSHTSSSDQITPPLSPTSMDFMMRSNHTSVYDGDQGSVRSAAGSFSAESTANPRSPTTSQGRFMAVTRQEELLLAALRKKRLRMRESIIAEFEEEQEKEKAHGQEQDNIAAPQPAKPAHEIRRRSIDAVLELHAPQPRSISAASVSFNDFPMHFEDAAFPVPPSTGIRNSLRSSSAMSMPLSPRSKPPTAQLPPTPTAKSTPNADLDRVLMNLNKSTSTASGKASNSSGSGSGTGTASGSNSTPASDRSEDIFGGAARNRDSNSSPRLSDCLNFDNDEVDDEADEEDGAASESVESYDSFNFQTPADQSPIDPPAAATASHRHNRQLPFRAHQQQYLGVAKTIPSPTLPTVHDDFEFEEFGEYDDVDEVDVSDIDGDYPAHNVDAQADLQFNHFSASNSNRQSQNKNSHNSYYGQADDDDEQGIPRPDSPLESPLPFLHKRAVRISAVGGGTRVGMEAGWWGHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ94</accession>
    <name>A0ABR3YJ94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arginine metabolism regulation protein II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARG81</name>
        <name evidence="8" type="ORF">Sste5346_009912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="565" mass="63008" checksum="B4C87C1BFDDC261F" modified="2025-10-08" version="1">MSDDDIMKALATLDATPSPTRTETIGPFAIFKVEGFPEAEVVAETEADIDADAEGEADPQLDTAPTAHITTSTTTQPYDSASPAIDIDSDPDTYRLDDRFDELVDDIIDTSSPHLGLSMPLFRDSQTAYLLYHFTNHVAELLQPVHHPGNPWRTTYFSFALEGCPDLWLAQTSTNPASHASLSLFHSLLSSAAFHLRNATDGSVDYHRLALHHRIKALQALNAATPQPSNQQLYLIHLTAMLSLVTVDTMAGEDSDFPVHLKACYQLKKPPALLDQDGAEVEGSGSNSQIYSICRFLTLLARTTSPVIVARPWKVFPNDSDDIPARFSVPNFRDTERSVEYMYGITPALGNMLAQTCQMAEHLAYYQQQRNSREPLLKPLQQAIAALGDDIAGWSVDDEPFGLIQADNEAGEHTMREIARCQARAFHGAVLLYYCRTLLTYGLQDRRVAPVSVDVHAQVQVIWAQLTTAEDLKDAYYHRFSDGMKRSAPMSWPAFIAACEAAPADRPLWVAWWERVNGYRIGNFARQWQIIQDVWQLQDRTEEQGHGRIGWREALARTGKLVLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJZ2</accession>
    <name>A0ABR3YJZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein RAP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Chromosome</location>
            <location evidence="5">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the RAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11655">
        <property type="entry name" value="rap1_myb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039595">
        <property type="entry name" value="TE2IP/Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015010">
        <property type="entry name" value="TERF2IP_Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466">
        <property type="entry name" value="TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466:SF6">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08914">
        <property type="entry name" value="Myb_Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="495"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="573"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="645"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="724" mass="81990" checksum="20EF3ABDB1923083" modified="2025-10-08" version="1">MPFSFEGLKFYVSINAPNRTKKAIQDNGGIVTADERKANIRITDPSRPIPSYSSGDYYSYEWVLDSVRQQRQIDETPYKIDRPVAVPPPPQPASRPQARAPEPTARSDGLIYAPANSQRRHRNAFTYEDDRILRDWVMEEARIALRRDEKFLDRGNDMYKRLEKKYPHHTFHSWRNRWLTKLALTTNIPVAKRQEPRSRPPRVEPPQEESEEEIEDVPDVQPASQASPEQPREATPEAPREEPQGQQRDNAQEAAQEEPAHDENSGRPDELFFMNYTDYYILARAYSAWKREKRESGISPKPTETFFKKLHEQHPDVSVKDFRRRYHRLRNLYTKSNATPAGSPVKATATTAASPSVNHQNDVPNGEQEEGADDNADEMEVDGLDLDDDAILNGVGDHDSAQQEFQKCLDDYNDYLTLYVPPSFYIGGRFLDTYSLWTALQDSVDDNDRIDWGAVIETLGLDRAKHPQLASQLSAWYDLNLKEFRSFWNKYKEAVEEAEEEESEDDEEAEGEGGEEEEGEEAEDEPSGSARRSTGTGFVSSILGIFGGGGSSGSTQAPESPSKHVRFSGAQAAEEEEESAQEDEEDDDDDEEDDFETRRVTRSASQQLQTPKKQKQRQTPKKAALEPETQDFAFDPETQAPLDLAGDDEIEDMEEDEENEEEDWRPLSSSKKATPARQLRTEERVVAAVPQSLPPPGSAKRKRTAAAASSTATPAKRLQRKSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK68</accession>
    <name>A0ABR3YK68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NFS1</name>
        <name evidence="14" type="ORF">Sste5346_009405</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(sulfur carrier)-H + L-cysteine = (sulfur carrier)-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="13">
        <location>
            <begin position="133"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="57915" checksum="244B88CA78FF626D" modified="2025-10-08" version="1">MPAISSQALLLRQAARLASRPSAPAASASASALRRMHSGRSRLAPTAAVQSQSQSQSPAQSRRTYVSESKRDNAQVAEATKIETAIHLNKKDFQNALGEVPVPTAGSGADVLVSPMAEVLKQATVLEEGQRPIYLDMQATTPVDPRVLDAMMPFYVGIYGNPHSRTHSYGWESEKAVDEAREHVARLIGADPKEIIFTSGATESNNMSIKGVARFFGRSGKKKHIITTQTEHKCVLDSCRHLQDEGFEITYLPVLASGLVDLEALEAAIRPETALVSIMAVNNEIGVIQPLAEIGRLCRKNKVFFHTDGAQAVGKIALDVNAMNIDLMSISSHKIYGPMGIGACYVRRRPRVRLDPIITGGGQERGLRSGTLAPPLVVGFGEACRIAHEEFAYDSKRIKFLSGRLLNGLLAMEHTSQNGDRDHFYPGCVNVSFAYVEGESLLMALKDIALSSGSACTSASLEPSYVLRALGNSDESAHSSIRFGIGRFTTEQEIDYVLQAVRERVSFLRELSPLWEMVQDGIDLDSIQWTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKW3</accession>
    <name>A0ABR3YKW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Centromere protein X</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009237</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-X/MHF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22921">
        <property type="entry name" value="HFD_CENP-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018552">
        <property type="entry name" value="CENP-X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28680">
        <property type="entry name" value="CENTROMERE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28680:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09415">
        <property type="entry name" value="CENP-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22499" checksum="C8F6F7CF114CC320" modified="2025-10-08" version="1">MPPQISSARPGARGTPTGSSSGFRGTGAFKPPRPVAGAARSTTAATSTSKSSRSRAVDVEISDDDNDNSERQQGREQEEDDDVDELERSRISSANQRRRTIDQFQEGQEAEEGAATDVATDNDDDIPEALARKTLPPALLTRLLYHFFQNQGGTPTRMTQDAHASVNKYMEIFIREAVARSVAERGNGAFLDVDVLQKVAGQLIMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL65</accession>
    <name>A0ABR3YL65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009139</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF26">
        <property type="entry name" value="L-SACCHAROPINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="48572" checksum="49E0C4615FABE4C4" modified="2025-10-08" version="1">MADKDDRVLIVGGGAWGLSTALFLVEAGYTNVTILERANSIPSPYSAAYDLNKIVRAEYEDAFYTELALKAIQAWKTPLFAPHYHQTGYIVATSGSAPDKAIATLEKSLASVEKHPVFAPGIQRLDGPDAFRKHAWQLSGPLTGFRGYINPLGGYAHSANCLQAVWEHVSACGVRSILGNKAGCAVRLEYAEDAGQVKVTGVVTADGKTHPAHLVICALGAHGAALVPQLGANNANVARCWSVAHVQLTESECNLLRGLPTTNVRDLGFFFEPDPKTRLFKLCPLGAGYTNYDSRVNGVSLPPDNKRGFQPNAIPKADELKLRRLLQETFPWMAGRPFVDTKLCWFSDTADSNYCIDFVPNTNRSVVALSGDSGHGFKMMPIFGQWVVDLLTRGQQTEPRWQWRAHSKDCAQWGDSVSWRVGEAAEWKDILEEQEEAGVGRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLA9</accession>
    <name>A0ABR3YLA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="94"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="297" mass="33823" checksum="E08CCF8EC830C404" modified="2025-10-08" version="1">MPPKTESELADRRTRYEEDLPEDRDNKVAQLLQEYSHIPADEIEPHLRSVRDRAWAIFPYTCIGAWRFLDLYVTKLPVYASVLGRLRDGGDRLLDAGCCFGYVLRQLAADGAPTSSLAGSDLEQPFIDLGYELFRDKDTFKGSFVAANMLSPDGEGREELNALDGTFDIVHAASFFHLFSWDDQVKLGERVVRFFRPADSSKKTNSGQPRLLFGRQVANIAPLTREELAARGEYRFHHNPATLQQLWDEIGDKTKTKWRVEAELVPETGRGRREPAADGTGKEPHKFQLWFAIYQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLI3</accession>
    <name>A0ABR3YLI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1237 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000086">
        <property type="protein sequence ID" value="KAL1888747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028846">
        <property type="entry name" value="UCP028846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046582552" description="DUF1237 domain containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="65760" checksum="2AE83856456822EB" modified="2025-10-08" version="1">MVRLGRVVGAAAAAVVAVAPVSARPSPDESTSSENNDNNNVASCPDYTSFSTSRDHQPYSGGRLNLPYQRPPPECRRFKAPEVEETIDAMRKLVRDPDLFRLFENCFPNTLDTAIAWHGLGEGTTDEELTFVTTGDINAMWLRDSANQLQSYRSLLGKKRKAKKEDDDKGLSSIASLFRGTINLQARYIQNSPHCNAFRPPAESGLTVTGGFGGGDIVYPPVAHEVVFECKYELDSLAAFLQLSYDYYAATDDGAFFGKVFKKNGESGDGDDAEFRSTWVLAVEAIMATAEEMTKGTYGPDGRSQFSPYQFQRPTSVATETLPNAGAGPPVQGGTGMVRSAFRPSDDACTHQLFVPANMMLARYLAACAPIMAQLGRAHAPAKSDSLRESPLLDAAAVADDDYSNYRQGHRSRYYHELAIRMTDFAEAVRLGIERHGRVHHPVHGDVYAYEVDGFGSHNLMDDANIPSLLSAPLLGYVDRHDPVYLNTRRLVLSRSNPYYMTGPVINGTGGPHVGTGMAWPMSLVVQIMTTDDDYEITVALRQLLTSTDGLGLMHESVSSHDESVWTRQWFSWANGLFGQMLLDLRDRKPHLLATSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLR1</accession>
    <name>A0ABR3YLR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AN1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057358">
        <property type="entry name" value="UBL_ZFAND1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF40">
        <property type="entry name" value="CDC48-ASSOCIATED UBIQUITIN-LIKE_ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25327">
        <property type="entry name" value="UBL_ZFAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="6">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="6">
        <location>
            <begin position="120"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="36982" checksum="D15FB9405C63C919" modified="2025-10-08" version="1">MSSQRPNKQGASSSSSTPSSSSNTPTPTPSSSDTSYVNMTDVADNHATDVSLTGKHCQYEYCRQLDFLPFFCQSCRKTFCLDHRTETSHHCAHEGAWAERRRQAQLARPSAGADRTMRDLISQKPCASPACKTVVGTSLVPGVHCSNCNRDYCLKHRLREDHNCANLQPIGARPGGTAMADSAAKAKSALDKLRAWGAAKKEQANKAIPRPAAQQSAAARMAALTDLKKTAKGDAKIPAEKRLYLHVEAEAASTQAKLPKGKFYYQKDWVVGRVLDAAARNLQIDNINNKSSKEEDKLRIFHVEGGRLLEFNEQAGKALANGNTIVLLRGVGPPPELINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLY7</accession>
    <name>A0ABR3YLY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Leucine rich repeat domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008938</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="663"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="874"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="938"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="874"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="944"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="979" mass="106468" checksum="1E1E1426A490EC5E" modified="2025-10-08" version="1">MDSEDGELFIKQLAAFVRTHEKALANALQFRRQTAPRHGPSQSVSSLPTSSSTNTLPERPSTSSSTSSSLAAALSLGSLNFTSHSVKSAKLALTPHHLFYLLSRFEELGIPVGPMGIRIENIHDAAASTNYVSFLSQSQRSKTHGSDVGSIRSVSSIRSVMSGMSALWSSFSLGSSISAARTERQKAALQADLKYLYSAFTKIPCLRLAPDWRARLIRGYEEFPFDSAVPLYVFKNVQALEVCDMDFRQFFGWDRLADQLRSLTLKRASIEDPIEILVDIVLDDMEKRRRRTSKTQSSPTIGPFSGGSGGGSMGMSPRRSSPSIPHAELHKSMSMPGSPDPRTSALDMRIGSVISELTTDDQSEQHGSDFRPSLARSNSDEASPHSPGKPSRPRSHSPRRPSSSRNGTSYVRGSHKVHRSGSGSSHSSLSDSWHNRRGSTSNLLTVGVLPATKWRFLKHLSLADNSLTSIPAFSLSPLSNTLHSLDLSSNLFTQIPDSLATLTALRALNLSHCMIDSLHSLAHFPLPAISALNLRANRLQSIAGIEKLFPLERLDLRDNGLTDPTELARLTGIPDIREVWVGGNPFTRTHKDYRITIFNLFRKTPGFTEDIIIDATGPSYSERKYLVERAPLPPMVPVIKPQPVPTIPAIDVSKPAIVYDAPRDSRDTRETREPTVLRKERPTVRAVSGESNTNATRRKRAPKRRIVDLATNNVTSTRVPSSSSIAPVLPPPSAPSPLDTSFDRTTAAVPPPLAAVPETSYLTTNDDNYLMSRSPKDTRPLPALPHAAAREAPVPSAAAVPVLLEEKSAAPRKNISPLPVDSSATFTVAEVQVLTNGNSNGTDAPTSARLAQALPPLPPQSPLTVQPPVFNAPATPITPTRTPTKTNNTSSPSQAVPWNEPQDWDVGGELYRRKIEALRDQVGEGYLSVLSEETWDPVRHPSQYHDNPFSSANTSPLHPSPVAPRPTSVQAIHSGRTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMM2</accession>
    <name>A0ABR3YMM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6923 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054215">
        <property type="entry name" value="DUF6923"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21959">
        <property type="entry name" value="DUF6923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6923" evidence="1">
        <location>
            <begin position="321"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="544" mass="56327" checksum="BB3E74457C354A3B" modified="2025-10-08" version="1">MPFVGAMVASTALAGDNLCTPLAEAPYVTEALVILVELSTTITTTGVVTLGVDFPAASGLYCVAKTTTVTAAPTVCAVTALSTALTSSRCSVATTFTSCGEGDVCGTCSFPETYCWTPKPPPAATSTRIPSVSGTCPVLVETVTETATETITDAGATVKETVTDAGGDMVTETVTETVADVGETVTETMTTTDTMTVTDTVGRATVTLPPVTDVVTSYVTVAASRSYGYNHTISVVSQPANVTKTETLTVTEVSSTESVAYSTATVTITAVSSTASVAYSTATVTITEAPSLSSAAACSTVTASGGVSLSCDKYGYLIQSQALIQIDLASGDYTTITEDVGSSGLVNALGYNVLDNYLYGRDAGNNYIVRIGADGTSEKVTALTENVAGVVGDIDNEGNYWYATGEVTSWYQHDLLPGSPTYGAILNSGTLAATGRRIYDWVYIPVTGRYLWTIGTNSPSGGADLMQWSLETHTWTVVQNYPDITTDTFGALYGMNNGTIYASDNASGYIWAFDTSTTLAPYIASYGPVSSSNDGARCVLNLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMS5</accession>
    <name>A0ABR3YMS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949430" evidence="2">
        <location>
            <begin position="20"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="221" mass="21759" checksum="79AD3B35BD59507D" modified="2025-10-08" version="1">MPNMFTLGYLASIVTVAMAQHGPPSSPGGGPEGPGGGGFPGGGGVGGGAGWQHTTPPGGVPMTTPPGAPIPPSSSPLPPPPEPATSTPVVVAPPPPPVETLPPVPPPATVATTGTTSYTVGPDGLTTPVAFTTGPNGIATPVAYTTGVNGLATPVVYTTGPNGLATPVVYTTGPNGLETPVTQTYVSYTTGTDGLVTPVTNGVVFTPFISNGQRLEPFRFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMU3</accession>
    <name>A0ABR3YMU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hsp70 family chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF82">
        <property type="entry name" value="FAMILY CHAPERONE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G08575)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="853" mass="90887" checksum="61D3026F8893C1DB" modified="2025-10-08" version="1">MNNNGGPLRPPPPPAQRSRDARSNYFATYTSSPISTPTPPPPPPPPSLNAAAAAAAAAAGTAAATHTPTPPPPPPPPRIHASTSPSSSLLLTPTSLSAASLAANQAASKAGGARGPVYSPTSPTSLGPATNLIQGGTNSASSSTTSLFRSNSNSTNVAGGAIIGASVVSPAVPKLTSSGTPNPPSAAEAIHGPVREPVREFTPPTDRLIVGVDFGTTFSGVAAVYTPMPDDIEIIKTWPGGNGITSDKVPTEMTYDLPIDAPPGTEPTVRWGFQFKPEESRLRCIKLFLDRTQKLPFYVSPLETAAQLSRYKKTVVDAVADYLTQVYKHTMDTLSRRYGASFMASTRVDFVLTCPAVWSDAAKNTTLLAAERAGMGDRSSIQMISEPEAAAVYTLKAIQPNHLNVGDNFIVCDGGGGTVDLIAYKIISLKPLRVEESAVGTGGLCGSAFLNYRFEEHVCRRLGQSRFDEMKTKKSKTWQMGLRYFEEFVKRNFNEDEHQEVNIPFPGLPDDEEAGLDSGFLVMSAEQVLEIFEPIVKEVCDLVQGQVDKLRAKGGIVSGIILVGGFGQSDYLYRRLKHHFRGNLMDGLASHGTGSSQLPPPPYSERPTHAAAASLDIANLSLSDGGANGAAPIPPIEVMQPVYAWTAVVRGAVLRGLEGSMVLSRRARFHYGTSYATVYDEAKHSVSERYWSPLWERWMVSDRMQWHIAKGDSISPLSPIAFHYTRNFRPGQSLIVTDDLIACAADEPPESYARGGGGGALGLGKGGVQNGSSENVAGGDGADGNGNNLIHVCTLTTDLSAVPRSLFTRLTTTRGVEFDNLDFTLEMVVDSAGLGFELKVDGVRYGRVEADFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMV2</accession>
    <name>A0ABR3YMV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Saponin hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046578949" description="Saponin hydrolase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="68724" checksum="9448A9EAE735AABD" modified="2025-10-08" version="1">MRLHATATAACFIGLSASTVLASAAIPSPPSPEPVSITELPLPPIVSNNNTGACTTKINPRGTGCLANGVFNTFQSGDFLPDGKHVLAQVIFAGAPAAPDPASIYSGMHVILVKTDGTTFPNGDPWKCVTCGVPAENAVGIDNSQYDYAQAFRDGSRLLIGKNVLDCGPHQVASEACTPNNTFIYPLYWSVTADGSGSTGAFREQRLHPDNVHIEFNAFTFEDGALGELAYFARIRFNPSPTTGVPLAPRYDVVNVTGLYNTGAPSFFGTDDGNTLTINYSAIAVGESRGFNGDGTEVTYIGPSWESCNIDVFAVHLTTGAVRRLTDNPEYCDPVAFSPDNKWMAIMDTRGSGRQMFLAGMRGIPPLVDIVASVLPSSTRNNGVRRFFEPYLLDFYGDRGAYNGQRIIEDSVFGYEYVNDSNHGVRGSGRVSDPEWNGMADPRWSLDSTRVVFWQTLATAPDCGGANPLPCYPSQEPNGRDYRMYVATFTRRTPSLPAPVQEHADVIPWGTPYVPGSAGPASTRLASGVYTLHGQASGHATVNLTWGTTTIGTVSVVYENYSDDGQSYLNGCEGVTASVADLYVYSFTWYSDITQSGAVNGTKKTGSSGYQATINVETNILTSNGSLVTTINGVEWRSPLSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMW7</accession>
    <name>A0ABR3YMW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutaminase</fullName>
            <ecNumber evidence="3">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002134">
        <property type="entry name" value="PRK00971.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="GLUTAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544:SF29">
        <property type="entry name" value="GLUTAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="456" mass="49004" checksum="DBB919C579C294B9" modified="2025-10-08" version="1">MKSPIPDYLRNVLEKARPLEGGEPANYIDVLADADPSRMAVSLCTVDGSVYSVGDDEVEFSIQSISKPFVYALAIQDQGLEAVLEKVGVEPSGDAFNRLSLEAGTNRPMNPMINAGAVATHALIASPNGSVEKRVDRIVQALSRLAGRQLHVDQEVYEAELKDANRNMGIGYMLKAAGMIACDPQDAVRGYIAQCSINVNVRDLAVMAATLGNAGIHPVSGERIIPQESVRQVLSVMATCGMYNSSGEWISNVGIPAKSGVSGGIIGALPGQLGLAVFSPRLDERGNSVRGVAMCKKLSHDMGFHMMDMSQIGRASVRSWTTTIAGGSKMPHACEEQVAVFELRGAVRFAGAERLTRAIMREIRPDEKGREGRPCAVIFSFRHTYSLNDVARRLIHENIHRLAVDTNVVVIDPAGVLKLPEDDPMKPIVAVVQNEAEARDYVGGIGCKIVSTADDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNJ2</accession>
    <name>A0ABR3YNJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_008645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="613"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="654"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="715"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="776"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="396"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="208"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="805" mass="85548" checksum="6978FD42C740D7B8" modified="2025-10-08" version="1">MAPEGASNAPTGNTNDNSNSSNDRAAATFSTSAVTDSPFRTGSVSSAGFRSVQFAAPRRNRRGSGGDDDGDNDDNDASSRFLDDNDDDGERDPYDNRGAGDWPPLRRRRSSVGARLAALTDIGGVNSIRSFTRSFQRAAGFTEVIPQRPSFIFAADQEPIFGGPHGEAGPHDHYADGMDESVDPGSSSYRASPPAFLSLLRQHLEARDSSAIASSENASLNAPPSDPGSPIPGQSSVVVTDEPNSSHPGGPSEHKSLLDPSGQTRTFRAGSTSSIFAWPPHLAAAAAAASAGASVEGVGSPPVVGSYGSFHTYRSGSGGAASGYGSVIGSPAALSYGAMSGRLGPGSQAASMAQAGTLWRQQQEGGLEVVPDSERPAILVKEVEEDGKIILTVEGQSTLPQTIFNSINVLIGVGLLSLPMGIKYAGWICGMIILFLAAAVTAYTARLLAKCMDLDPVVITFSDLAFISFGPRARLVTSLLFTVELMAACVALIVLFADSLDLLFPGMLTLVEWKILCCFIMIPLNFLPMRLLSVTSIIGIVSCFSIVAIVVVDGFTKKTTPGSLIEPAVTYLFPANWLTLPLSFGLLMSPWGGHSVFPNIYRDMRHPYKYARAIKVTFSFTYLLDTVTAVAGLLMFGDDVKDEITANILTTSGYSQALTIFLCIFIAIIPLTKIPLNARPIITTVEILTGMHQQTAPDTQVLTGRSMYFRGIAKVAIRVVTIVMFLIISIVFPAFDSIMAFMGSALCFTICVTLPILFHLKLFGHEISKADKLFQYAILATSIVISIIGTVWSFLPKSLIGVEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNL3</accession>
    <name>A0ABR3YNL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12163">
        <property type="entry name" value="2-Hacid_dh_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="147"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="245"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="395" mass="43482" checksum="E13C820473AB3350" modified="2025-10-08" version="1">MASATAGIGPNDVLLVFLPDRTAPDADWITRIEGTYPGLKVRLVSQADPSTGQVRDVNSLPAEVWDGVTLLVSHWPPRTTDTKVFSYAVQTTIKPKTTLPNLRFVQVPSAGADRWIGHETFQRPGVTIATGNGTHAPQIAEWVIGTWLMARHHFLQFAAYMPTGNSWEHRFDYMGEDSTNTRIGILGYGAIGRQVAKLAAAFGMEVYAYTRSERSTPESRADPDTYCVPGTGDPDGLLPSKWFHGTETDDINKFLSQNLDLLVVATPLTASTTKLLGSDQFAVLDQSRTGNLRNGKPKPKTYVINIARGKVIDTDAILHALHNYQISGAALDVTDPEPLPADHALWKAPNVFIAPHVSWQSNHMRERLLGVLELNLERLHAGKPLVNVLHKELKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNZ2</accession>
    <name>A0ABR3YNZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="220" mass="23875" checksum="45C40F82A190E4EB" modified="2025-10-08" version="1">MAPTSISLRAPPSIWERAATIVARQTGNSVSTSTDGFDYDTSTPEGAHLAAIIVPSILGAILLAGGAYYTYRHFIRKRRTTKDYFERIRNGLFYTVMLTIGLPIFLGFMAFSGIKGWRDRRRDRIAFERAGTDTVTQPSSGTRAPETTVSADFAVTTVEMTDNNAKAATPATSSYNTATSYSTPGSYNAYMAARSNGPQPEEARVPTPPPSYEKSSSGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPH6</accession>
    <name>A0ABR3YPH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="641" mass="69240" checksum="31FC8377A686EF41" modified="2025-10-08" version="1">MDELALRQLNGVEDEDEALRQALALSMVDEAPEASETTQNDAHVGGHHSPESPDARSRAHVRSLSDATTASTASTASTASLAPAAPKPASSNDDTSLSNRASDPTKRDAPNALKEAVATVFVVSSSPSTTPAAATTTTAPAMSLLGLDRKAMEAERLARRQKALEAQQAPSASKIDAPGSYDGAQDSGSPSKQDSSHLVQSWKLHTSPQKKRKLEEEDVIVIDDDEDDESDETKKETHHADAPAVRRRKIESETAKGKGTEAPALALVRPSQSAAAASTSASATTSSSSSMTRLPYAKGVVKKTWVRGQPRRGDDITVDEIWQKDTLELAVLSSFQWDEDWMMSRLDIKKTRVMLIAYAVDDLQKEQMKTNSRGSNIRFCFPPMQTMGYMHSKLQLLKFPGHLRLVVPTGNLVPYDWGEAGTLENGVDVAMVQSLRSYDFSETAKYAFVHSIAGSHMDESWKRTGYSGLGRAVKAMGWESNSPIQLDYITASIGSISDDLLNALYYACQGDSGLKELGSRTSKPRGGKGKSIAALSAAPANPNSPKNRLRLYFPSEETVDSSLGGRNNAGTICFQKKWWDAPTFPQSILRDVQSVRKGVLLHTKLLLVRTGSSTQGNEPGQAARPQGWAYLGSANMSESAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPV7</accession>
    <name>A0ABR3YPV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="227" mass="25919" checksum="E491EC07484DDE30" modified="2025-10-08" version="1">MSSLAARRIARRPALESKLQHMSQKLEWLVNVDNLLPHPSFPGNILQFWLLTDDQLEAMASYYHQRTPSEYTGCYPCPVSWPRNGLTLEDKRRKFGRFIGLRGCQTPQRSTHSCRGHPKRSTKQTCRGECKMSWGDERICMPCSLRKIDEIFAEGDTLSSAPTVVETDTDMDVDMDGDTVMDDYDDSYYNAAEEKPLTVEDVVENAQRARLAATAGDEMMRRKTGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQL4</accession>
    <name>A0ABR3YQL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="72"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="292" mass="31496" checksum="F269C5FF54F8B384" modified="2025-10-08" version="1">MSLYTDFEVTQAYAAIFGKNAIGAALDDRVPEPGSSRPVAARRAGTDAFGTMWYAKQGAQISQDEATPTAAVIYIHGGGMILGSVANYDFLVERYASESGVPFLAVEYRLCPEVVYPAPIEDCYAAVKWLHEQAATLNVDSARIAVMGDSAGGLYAAWTNDCIAKQLLLCPVLDDRTQARDNLRGLTSLGFADVDTAWWAFLGNMYGTSNVPEEAAPGRLVDATGLPELDLFCVEDTAYAVKHMQAGIRTELHIHPGVPHGWEVVAPHAAISKRAFADRTRTIQAIGQKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQW2</accession>
    <name>A0ABR3YQW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008061</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="595" mass="64656" checksum="4469E83003233AD3" modified="2025-10-08" version="1">MTRVKPGERKRAKAPKMYVKLKLGKEQTVRKVKCDETRPACLRCKSTGRTCDGFDPLQSNGSTNGNSNGQPVALTHRPSGRMSMSSSSASLSPSLSMHRISPSSYGDPLEARSLLYFTERTIGQFQAFFPDDFWNSHVLQFALSQDCIRHALVSLSAHHERYSRPRAGVPAISSTTDVGNANIGRADAERAFAIKQHNLAIQSLLACGDPSKALHVHLVSCLIFICIEALQGELRSAIRLFKHGLSMIDELNRRTGILGETIGGSKGPTNPPPVTEVTTDTSANTSASTSASSSSTSSPLPSPSPPTPTTPSFSDSIVNAVVAFLNRFAVQVALLAGDIDPDVSIGVMAGASSKPTLSPQTRFHSLLEARESILNLAIHVISGSPGALFGDGFLESGVLMLSWWTAAFDRMVDERGPSLSKRGIALLELHKRYLAAHLKLPNPSNSDERWDNHVAEFLELVSWAERALEPDVPTPGAPNPAAKIGLPTFHMDLGVIPVMFSTVLRCRDPEVRRRALAVLRNHRLQEGIWDSSLTLRAAERIVMLEESSIAITAAAGANRKPQRVKSVMVHMDPNEKVATLQYGLEDHTFEEVLDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRN6</accession>
    <name>A0ABR3YRN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="469" mass="51375" checksum="200AA853B4FD4D16" modified="2025-10-08" version="1">MLPSRPYSSLKGMLPTIHHPLPLNEKSRKKLLDTLTTSFRKHLDREHGLGDEPEDAIVSATSAAKKTAANIHAKATKPVASTSTEMSTLTTTTATSSARHRPTDRHLGAILSNPLFTYDQLTRKPNLTPTITKTVPSAASTTLLTSTDGVAPATPSDQRDPMEIFDWAVARGLMTTKRAAGCLLAKRREAVQSSHALAKTFMADTSAGLRVLQWLRSSGLERDMSFVSDTQFTAVLIQFLAAEPGMDAVVWMWIDRLQQAQGPGTVTVRSRGSPEYHVSSASFVLDALVRAKAGGADTLDDAYRAMRQAADLTKDVSQATTASSTIYWPWLELSWMSTLKAYNLTNPTPSLYESFASIMDNDARPSVLIERAHLDLRHPTKPSPAPAQALLDNDKLLTRVLNHRMPAEPAIGRRPAHAARFVSMGLDTVRHLAFVGQSDEAQRILHRLRSKFGDNIEQRQVRAWGGLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRR6</accession>
    <name>A0ABR3YRR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="91"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="357" mass="39013" checksum="4EDF6FD24B298841" modified="2025-10-08" version="1">MEQALPSGAGLQSVLTHDDIPGLVVLLAVLSIGAGEGDTQDTTDDTESGLAYITAGFGLVAHLISRPYLRSVQAFLLLAIGLRLRARDGQSWYLLGQAVRVAHSIGLHRQIAGNASGNSDSSLQSRVWWSLYSLEKLMELETGRPSAISNDEPLPPPPPITDSSDIFPPWVALATILGQISRRLYVQKPASAHALLNEIGYLDQQLQSWMTSLPEQLKPSYDVVTSQSSPSTAVLTTFLALQYYHAQMAVLRAAIVFPTKTFAAEVERAFPNGMSTNNKHRLLQAESFCTAAARSTVHRVLDLADGMVLSSSSHLLSPTLTFQAAVIVSSWRLPLYIWKHNMQVLDSIQDSFEDWPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS55</accession>
    <name>A0ABR3YS55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018830">
        <property type="entry name" value="DUF2434"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10361">
        <property type="entry name" value="DUF2434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="574" mass="65299" checksum="4B79AF9974AA8A2D" modified="2025-10-08" version="1">MGNVFDAREILSFPGGANSSDTLVAGVHFNLTALEHWNYTLFSNGTLSNGSRCLLTFAPYTPTLLYPNGTFINSTSCYSPVNPIGARAKIGIAFAVMYAVALFFVLINLRKHGRLFLPSEKRFRPIGRRWQWYWGILLCVAAFISLFMNIDVDRYYLPELPIVLTSFFWYLMQMCAMALVWEAVRHWGSWMERQYIDPNPFVLGEDDRRYKFELLIPLVFYLFLWLNFFLVVPRSWGNIEKQRSPEQIVDIAAPNATDARFKTAAFLLLAAWIITVVSLRHSIKHYLPRNRGVFNRAVGVISSTPPRLAVLLFLSLAMIAYQALCAWEFQWSVLKVDGDRLPIYLGGYTPPLLILIVQNIYGLLVFNEDRQLIHQRRQRGAEQDRELGIVHKPAWWRRINGDYIPTNESMRDRIARNVREVGGGAATTRGIDNAMDQRALELEELERARQRARENGEPIEMGPISRTTTAASSVYGSSRPPVFENYGGKSDRRRGERTMAVVASMLFPGESSAPTPDERREELFQEGPPPYADNEPNRGRSRQQSTQHSTRTNSTGTLVSVSGPAQQVRSMLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT91</accession>
    <name>A0ABR3YT91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycoside hydrolase family 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008225</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050226">
        <property type="entry name" value="NagZ_Beta-hexosaminidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480">
        <property type="entry name" value="BETA-HEXOSAMINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="966"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="7">
        <location>
            <begin position="17"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="728"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="866"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="918"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="730"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="866"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="923"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1043" mass="110719" checksum="15FB8392E6172935" modified="2025-10-08" version="1">MSKKLDGDLDPLWEDLDWAIGQMLIMGWDGTEVTPQIRHLIEEHHLGSVLLTAKNLKSAHETAKLVQELQTIARNAGHPYPLLIALDQENGGVNSLFDEDYICQFPSAMGVAAAGSADLAYSIAKATATEVSACGVNMILGPVLDVLTNARYQPLGVRATSDDPQEVSQYGIAAMKGYKDAGLATCGKHFPSYGNLDFLGSSLDIPIITQTLEELSLSAIVPFRNAITSGRLDAMFVGGCGIANPSMNVSHACLSDQVVDDLLRNELGFRGVAFSECLEMEALSHEIGVKGGTVMAVEAGCDIVMLCRAYDVQLEAIAGLKLGYANGILTRDRIFTSLRRVLNLKNGCTSWAKALNPPGLSLLSKIHPSHLALSRKAYDDSITVMRDRDRLLPLSRSMHQHEELLLLTPLVKPLPASSATKTLENKQFGSSSASSQSIHDKWLHRDRGAIMSGEGVFRGLGRSLARARHGKLLHTSYTANGVRPVHENLIHRASTIIIVTADANRNLYQAGFTKHVSMMCSMLRANGQNKNLIVVAVSSPYDFAMDKTIGTYICTFDFTEMAMSALVRALFNEYNPSGTLPGTLRKSKKVLKSRRNWLVETYNRDRDGRGLDELLQAIARASGPHLQYLRSATASSFELNNPNIEESHLVVSNSSTQALYGFCATYFIKNSGIGIVGGLFVDPGKRNVSVGRSLHRTALRLLSQKPGVTKLQLGSCFPGVFPGIPVVDDSGSSTAGSTGNTPSGGSGGGASNAVAAGGPGSSGSAATSTASLRSWFARGGWEVAFPRRITNLVIPDLNRWSPPEGLTRHLANAGISFDLIQGPEIADGVLSHVASLAGPEVVELYRYALSQGNNKTCAVVRAKVAGGNNNNKKNGNGDSAEGNSGTEDAAEDTLLGTVIVCSPGSALANFFPPLQPLRSMHGSGSGGNGGGNGRSASLSTEDGGGLLSSGAPNSMAFDENTATGGIVAPVVVAGAGSASTLLLLQGLAMMAVRQNKNHRAVRSVLSWVADEAYEPLLAMQFEVLQAFDELTNTIENWSDLGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTB9</accession>
    <name>A0ABR3YTB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="7">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">QNS1</name>
        <name evidence="10" type="ORF">Sste5346_007633</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="4"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="700"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="700"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="721"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="730" mass="82117" checksum="5C0F50F320A2F972" modified="2025-10-08" version="1">MHLVTLSTCNLNQWALDFEGNTNRIIQSIHEAKKAGAKLRVGPELEVSGYDCLDHFLEGDLYLHCWQQMYRILTDKSCYGILLDIGMPVLHRGNRFNCRVLAIDGKIIMIRPKLFLASDGNYRENRYFIAWHGPRHVEEYYLPPMMQDLQGSIKVPIGDAVISTPDTCLGAETCEELFTPNSPHIGMGLSGCEIFTNSSGSHHSLRKLDIRISLILEATRKNGGVYLYSNCRGAGGERLYYDGCSMIIVNGNIVAQGSQFSLNDVEVITATVDLEEVRSYRFTPSRGMQAMQAPAYQRIEIPFSLSEDKLGLAPTKSQPPRYHLPEEEIALGPACYLYDYLRRSGASGFLLPLSGGIDSCSTAIIVFSMCRLAMAAVAEGNETVIADVKRLCRHAKAFPKTPEEFCNNIMHTIYMGMKTQSSKETRQRAETLARDIGSHHTDINIDDAFHSFKGLLTDATGFEPKFKVYGGGNTENLALQNIQARSRMVAAYEFAQLLPTVRFGEGAGGLLVLGSANVDECLRGYLTKYDCSSADINPIGSISKKDLKRFIAWGEKEFKLPILHEFLTAVPTAELEPITGDYVQSDEVDMGMTYDDLSTFGVLRKEMKLGPYYMFQKLVHDWKEERGLEPRQVAEKVKRFFAFYAINRHKMTTMTPSVHMETYSPDDNRFDHRPFLYPRMWDNWSFKMIDQDVERMEAAAAKEAENKERAAAEAQKVESKLGTTAQSDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU73</accession>
    <name>A0ABR3YU73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007706</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF165">
        <property type="entry name" value="DECARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="59082" checksum="963D2861E3FB963E" modified="2025-10-08" version="1">MSSITETDSNSDPRFLSDAYLRLRTAITRLVEQGADANDRNGKNDNTAPTLPAPARVQAALSALPKPGQADYLQPRGTRAALDHILDTVVPALNGQNLSGRYYGFVTGSVLPVAEAADNIVTALDQNLHAHLPAQTVSTSVEAAALQMLADVFGLGNGDWTGRIFTTGATASNVLGLAMGREAVISNRLQLRRGASGKTADSVAAAPNAVAELGLLRACQEAGVSDIRILTSMGHSSLYKAASIVGLGRAALVDLPYSDTEPWRLDISAVEKTLADASRFVGKEGKSGSSVAYIISVSAGEINTGRFATTGLADMQRLRVLADKYGAWIHVDAAFGLFTRALPDTPEFARIRQYTDGLELADSITSDGHKLLNVPYDAGIFFSRHARLQSEIFQNANAAYLTGGAAGSTSDRDGPSVPSPMNVGIENSRRFRALPVYAVLLSEGREGLAAILASMVRLARGIRQILRKLPEYETFGDEDTDDDTHIGVLFWAKDEAINADLATRINASRQMYVSPTAWRGRPACRVAVSSWRVAEGDLQVVETVLRNAVARGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUD1</accession>
    <name>A0ABR3YUD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purple acid phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007343</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044999047" description="Purple acid phosphatase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="8">
        <location>
            <begin position="82"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="279"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="7">
        <location>
            <begin position="538"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="715"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="763"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1126"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1201"/>
            <end position="1255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1278" mass="123420" checksum="4F3FC3AB37A5BE85" modified="2025-10-08" version="1">MKSSAQFSALAGAALLAVSGQAAPTVDTTYPYTGPDVPVGDWVDNGVNGNGKGFPRLVEPPAVTPGSANPTNNVNVISLAYVPGGINIHYQTPFGLGEAPAVAWGTSASALTNTATGASHSYDRTPPCSMVAAVTQCSQFFHEVQISGLKADTTYYYQIPAANGTTASDVLEFTTARAAGDDKPFTVAVLNDMGYTNAQGTYSQLKALTDDGTLAFAWHGGDISYADDWYSGILPCEDDWPVCYNGTSSSLPPGEDPDNAYDTPLPAGEIANQGGPNGGDMSVLYESNWDLWQQWLQAVAGKVPYMVMPGNHEAACAEFDGPNNELTAYLVDGETNSTASKTGLNYFSCPPSQRNYTAYQHRFRMPGAESGGVGNMWYSFDYGLAHFVSLDGETDYANSPEWPFIRDTAGVAEEPKESVTYITDSGPFGFIENNAYKTTSAYEQYQWLVNDLKSVNRTKTPWVFVMSHRPMYSSGYSSYQLYIREAFEAVLLEYGVDAYFAGHIHWYERLFPLGANGVIDSDSIINNNTYYANNGKSITHIVNGMAGNIESHSTLSSSETIEDMTAVLDTTHYGFTRLDIHNASVVTFDFVLGSGAGSGDSLTLIKKEASSSSSSSSSASSSHASTSAPASVASSAASTASSIESEDCSATSEEGSSSSASSAASVSSVPASASASASASASASASASASASAGSSSASASGSASNSVVIPPVSGSVSASASASGASSSAAPSSIADCETSSVSGASSASASASASASVPASISGSASASASPSSIADCETSSVSGSASASASGSASVPASVSGSASASPSSIADCETSSVSGSASASASASGSAIISASASSVSGSPSSIADCETSSVSGSSSASASASASVSGSAIVSAASSSVSPSSIADCETSSVSGSASSSASVGASGSVSASASVSASASISGSAIVSAASSSASVASSVGSSSIADCETSSVSGSASASASASGSAIVSASASSVVSGSASASKSAVSSASSSAIVSAASSSVSVASSAPASGSASASATGSASASNSGVVSASASKSAVSSNTVSASASASASASASSSNGAGTGAGSGATTTTEVVTAYTTYCPGATTFTQGSHTYTVSSATTLTITDCPCTLTHTISPASSSTPVVGGGSGSGSGSGSGSGSGSGSGSGSGSGSDSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSSAAGTTPAAGTTPAGTTPAGNTPAGSTPAAAATSTQGAASPSSSGSTVVTSSGMQNQASTLVASISALLVAVRLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUP6</accession>
    <name>A0ABR3YUP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="666" mass="73506" checksum="83C5E098E5EDDDFE" modified="2025-10-08" version="1">MDLTIMAPAASRLELLHPELVDLVVGELAFAPDISALRLTCRTLATRVAQSPGMRRFLARKTVELTVRELETFVAMTGPGCVVGHQLRHLTLKGIARNKTAVYMSKYSDLPPPSHPDEDPEQDQDTLLRNVPEEDPDDHWRLLTAAFSNLKKYGRHSSLASLALTIGPSTNPRAIYIVPRHKRGAGTFPEEVDAGIGSGGGGGEASGEASGDPDSDDDYVAPYELPYRPSWRSVWDASERTFDVVMDSLTIAQLPVTNELDIYQSVVACALPFDTFLKRMRDPALIPIFSSLKRLKVHMSLRHRTAADERKITAAEEARQDREAENDGVNEGLTISRLQAEFEAAYRAQVAAEQAATLRVLGAITAPTELTRVMPALEFVSVEWYHIGRNMVAPTEKDLALPPPLPPPTDREGTEDTDRRPLKRLQSISLHGMRLDGGEFLKFLDTARPEYLSLCYPQFTPGSFRPVLRYLTDPDLRSTTNIQEITNLDRRLAGLRPSPIRRFEIDDVMEGTVLVHYDVPGRPKFRYLDRPDLGPSTLVRPDPTIDRTAPMTQAVAAALAAAESESPEAESDTIPEEAPTAAAATSAAVLTETPEDPPGGVQMVLPTTRPMGSGSRWRWARHNGSVYGPPRARYDLPLLNPGMAQNPPPWRRLVGNIQKATEIPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUZ2</accession>
    <name>A0ABR3YUZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="490"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="592" mass="64925" checksum="316156A939485D2B" modified="2025-10-08" version="1">MVFESPASVPKLPIDPPDSIPIAEFMRNEAYGRYPIAQSRNPYTCGLTGTSYSWPEFFERSERIARALGAHKKLGWQPNAATPWDKVACLFSLNTIDYITVAYAVHRFSGIVTPANAAYSAPELQQQLTSANVKVLFTCLPLLEVALPAAKAAGIPDDQIFLLPVPNMDGSFPKNNTPFLTVEDLVKAGANAPTLPPLQWSQGQGARQPAFLCYSSGTSGLPKAVMISHRNVISNALQHATYESKARAKRGVKTQVVGAPLPFSHIFGLVAVCHSNPWRGDGVVVVPKFEFDMFLKVIQKHKANHLILVPPILVQMLNRLDVLKKYDLSSVNHIMSGAAPLAEEVVRGLQAAYPKWNIGQGWGMTETSTVVSWQDQDDVFLRGSGSLLPGARLKLMAPAPEDGSASVGREITEYDTPGEIFVQAPSVVLGYLHNERASDETFVHHDDGRWIRTGDEGLITKSPSGNEHLVVVDRIKELIKVKGFQVAPAELEAHILAHPQVSDVAVIQVPDERAGEVPKAFVVRAPSRKPEDDAELSKIVIQHVQDTMTHYKWLKGGVDVIEAIPKSPSGKILRRLLRDQEKEKRRKAGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWX6</accession>
    <name>A0ABR3YWX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224443" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="7">
        <location>
            <begin position="35"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="26"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="524" mass="57084" checksum="1DDEF0E8661F9A37" modified="2025-10-08" version="1">MLKKTPTGTWLPAWVPESSVTLSVLLILCSMVQSATNGYDGSMLNGLNILPSYYDYFELNAATTGLNTASVFIGGFFGPIISGIATDRLGRRPAIFWGSVITLIGIVLQTAAQNIAMFVVARIVLGFGAAISGIAGGVYLSETFASRYRAWGVGLLNDFYYVGALIAAGITLGTGEWQSTWAWRAPSLFQGIFSILCIAILPFIPESPRWLVHEGHFEAARAAVAQANSNGDILDPVSVAVYKEILDTLEWEKKDGRSMSPREIVRTPSARKRLLIGMSAGPFSCVAGNIIASYYLGPELDTAGITDTLQQLKANVVLNVWCLFCCLLGTHLVAKWGRKPTALLTQSLLVICLFIIGGLSKMYADDPDGASSSLVYGDVAVMFLFQGFYSIAWTPLLFLYPPEVMNYSIRANGLAFSSFMLNAFAVLFVFIMPIGLNNIGWKMYLVNGSWDIVIAVLIAVYWVETKGKTLEEIDAIFEGEKHSDVPDIEAVRRGEKTIDVAAIEMQLTAELSDLKQPHAQVEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXA2</accession>
    <name>A0ABR3YXA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="267"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="447" mass="49108" checksum="06FF9E439C5D0D6D" modified="2025-10-08" version="1">MSRPQYPPMSYHTQQSNSPASVASTSAHDQQRSLYGQPPPLHQQQMYYGQHQQYQPMPQSAAPSPYGQHTQAPHQSMGSQPGMMMSHGAPSPVPHQMAQHPSQHSPSALAGSPRHTKMEVQSLTPQLSRQTGPPNAPSPLSMGQVQAQNLQAQNMHAQNLQAHQAHQTQSLHSQQQQQHPQHVQHPQHAQHPQHPQHPQHPQHPQHPQQTAQHPQQHSAHTPQPNGTSPLPSGQAGNAGPSAVNPNAAPGPIPATTPLVVRQDQNGVQWIAFEYSRDRVKMEYTIRCDVESVSTDDLSPEFKQDNCVYPRACCPREQYRGNRLQYESECNTVGWSLAQLNPPLRGKRGLIQRAVDSWRNSNQDPRLRSRRVRRMAKMGTRKNAGSTPGSMTSGVGQQSPAHLGGPAQLPNIGAPMGKPMHGMPQQLSHHADTSAHAGGDEAGMFHQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXR4</accession>
    <name>A0ABR3YXR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006920</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="31897" checksum="CA6037A346053FF9" modified="2025-10-08" version="1">MASFAPPRADSTIAQKWFEESTSVDGEFRDLLENYSHVSSDSVVPHVVNTRNAAWQIHPYPCLGQFRFLELNLSHRDLYSRLLDDLKTQPDARFLDIGCCLGQDLRKLIYDGAPPERVAGAELNGAFIDLGYELFKDKKALAGKTPIVSANILEDPSSPSSPLYSLAGTFSAVQLGMLLHLFTWEEQITAFRYTLSLLRGNTGDRIFGQATGHLDGTPTASVSARATFKHNADTFTKLVTEFGQTTNTSWKIVTAELDNGLSVFDGKRTWDDPRTRRLVFEIERES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZE5</accession>
    <name>A0ABR3YZE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="9">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SMD2</name>
        <name evidence="11" type="ORF">Sste5346_006637</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="105" mass="12128" checksum="EB54027FC3967B9B" modified="2025-10-08" version="1">MADVNIQEYEIAQLEQWEFSNGPLSILQTAVRTHSQVLISIRSNRKLLARVKAFDRHCNMILENVKEMWTETPITNGKKGRPVNKDRFISKMFLRGDSVILVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z004</accession>
    <name>A0ABR3Z004_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Galactokinase</fullName>
            <ecNumber evidence="3">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">GAL1</name>
        <name evidence="17" type="ORF">Sste5346_006379</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13554"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF7">
        <property type="entry name" value="GALACTOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457">
        <property type="entry name" value="MEVALONATE KINASE/GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="9" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Galactokinase N-terminal" evidence="16">
        <location>
            <begin position="32"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="14">
        <location>
            <begin position="144"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="15">
        <location>
            <begin position="431"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1893549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="57521" checksum="62EBF9CE54782DB7" modified="2025-10-08" version="1">MTTVPVVDRLGQIYTDDAVPAQTTRWQHLLSVFKERHGKEADLVARSPGRVNVIGEHIDYSLYSVLPMAITGDCIIAVGVSDEAAIERSEDKKDKWTVEISNVLPKFAAHTFEFDADDEVSIDASVHEWTNYFKSGLRGALALLRKKRAAAGLSDLRPLSLQVVLDGTVPVGGGLSSSAAFTSCSALAVLAANDAEHRSQIDKTELTELAIVSERSVGVNSGGMDQSASVFSERGSALFVSFTPTLTARPVFFPTATSPETDNCFLIAQSFVAADKFVTGPIHYNLRVVECTLAAAYLNAALNPPTTKLPGDNGPLGISLHGFHETYFALQEQGGVANTPRTPKAQLQTLLELVDSTLSKEEGYTREEIASVLNVSVDSLNEQFMTTFPVRAERFKLRQRAQHVFGEALRVLEFMEVLDNAGHGDVATSEKLGALLNATQDSCRSLYECSCPELDELCAIARRAGSYGSRLTGAGWGGCSVHLVPANKVDAVRKAWDDEYYSKRPELTDEQRAAAVVLSRPGSGSAVFVGKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A4</accession>
    <name>A0ABR3Z0A4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclohexanone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="587" mass="66101" checksum="55C0899133F49BF0" modified="2025-10-08" version="1">MADASSTIIGPTTLSPDPATAGAPLNDDPHENEWYNQSFGDYVVTEQPLYTKRAIRIVCVGAGATGLQLAYKSEHLLENVTLQIYEKSADIGGTWLDNRYPGCTCDIPSHSYQFAWARNPSWSKYYASSPEIWQYFKDIASNFGLERYIKFEHKVVSAKWNEDDGVWELSISTPDGSFIADRCEILVNGTGVLNSWKYPDIPGLTTFKGKLMHTARWDEEYDLTGKTVAVIGGGSSAVQVVPSIQPKVKKLIPFLRSPTWISMGFGSKYAGPEGTNFEYSKEQIEGFKNDPAAYNKYCRELDGELNKRFTLNHFQSQDQKTARAGLETRMANQLHQDKRLTSHLVPDFALGCRRMTPGSGYLESLTRDNVEVVTDAVTRLTETGVVDGAGNEYPVDVVICATGFDSSFATPFQCVGRNGEELRSKFGDFPKGYLSVMVDNFPNLFLFIGPNGPASHSSLLPILEWHTRYLFQMVNKLQRENIKAFAPKAECVDEFGQHTHTLMKRLVWSAACRSWFKNGKSNGPVTAIWPGSRLHYFETLQVPRYEDFEIAYRSKNRFQFLGNGYTHEEIKPDGNPVWYFDDPFCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A8</accession>
    <name>A0ABR3Z0A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="271" mass="29544" checksum="A9DC50EA4214A244" modified="2025-10-08" version="1">MSGTNLGAGTGPVPDNGEGGNAAAIAPVTTGLLPPEHWTQLGQVRALKYHISSESQRYYLTCYMQVNVFDNDDTESARARANLSSTASISSSIVKYRTIQGRTYHSELGNASYCDFADQYPNATVIGTDISPIQPSDIDDYTREWSFPDNDFDFVHAYRVTAPGGYLESYEGSPNVRSDDDTLPSGTAMAQWGPLFINGGKLIGRSFSVVDDDIQKKAMAAAGFVDIQDRLIKVPSGPWTADPRVREIGVFSQRAVESDIEGFILFFTNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0P5</accession>
    <name>A0ABR3Z0P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43111">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43111:SF1">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="309" mass="33721" checksum="B9D0690640D2B8DF" modified="2025-10-08" version="1">MEGTSAASGKQLPYSRLRATVTDGRAANVFFRKNQLRRLNDELLGAKADLLKAITNDSGNTATEAWIEFYLTLSALKSYFDDLDPAQELQDEYRIAHGRDAADAREAVGIVYIQPDAHSYLYSVVVPIGAAIAAGNCVLVVIEQTLKVLPAVLQKLLQRSLDPDTLEIVQSQVEDTAFLSTCVQVIQTGTPRISNSTTLHSPRDAPVIGVVDRTADVEKAARDLVTARFSFGGRSPYAPDVVLVNEHVKTSFLNAAMRHSIRYLTEENVPLSGRMRKTEKKTSAASTQVDGIQVITSGSNGEILFVKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Q2</accession>
    <name>A0ABR3Z0Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RGR1</name>
        <name evidence="12" type="ORF">Sste5346_006274</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26204">
        <property type="entry name" value="Med14_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="11">
        <location>
            <begin position="72"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1118"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1169"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1239"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1124"/>
            <end position="1137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1266" mass="138128" checksum="699C693F392D494C" modified="2025-10-08" version="1">MAAAMENGTLNGGAVHTNHDRDAKPNGVNGDVSGGAGKMVNGDTSAAADTSATRSSRMNDLPDQIQHITTNYVPLGFLLQRLAQKTHNNLQDLIRELARKPVAGGPDGPPALPPGTDDGSLENLEKKKALLYFARNEHANWVKALVITEWSKKASQISKLIDLENHMFEEELVRYEQAVFTMLNLKRNLNAARVPSPDLKTALNVLSRGTAGWMPDLGFITPPPLNAQEQLKKLDDISTLLSLRLNLDDHDTIPYFFRDYSIASGRVTFKVPGEFEVDLTLASDDFTQQLWFLDLRFLFTPAPRDLTPSLRKALEDRVNGVLGLEGLPGCYRMLHEYVLTHKINEMRRQVRDLARGRWIDTVRVEQLNRAIAVQYWTSRHSGGNNSNTTGPTGNNNSEVRSWFIIGVHSGRDAASVDLPEEQITSRLTLRWFRDNKEVKDLGDDQINSILANILTDSEETTTVKSENEADDDSTTPSTTVTLCAETILQRIVALHVEHILTGIHTKLAAKPLFAKRLATMRLRISRTDASQSFLEIQLTNAGDRIWVRIDPVTGLFSLSPQQSRVVTHSEMRINAAAAGGSLSGGSAGTGGDPVEEGFVMLDNVRNLAAQEDLGRRAKSFGWQVVRNAGPGGGHLVKPDELRQVMNMRDSYQVLWLKRPDWAAPQWHVLASLSLSGDRWWLVKLAEQPPATAPTGPGQPPQAATSSARIVMQMLLPMGTSPSDLDDAFFSDLTIYATGVLAQYTDSQELSHRRKAAQATRVMNPYLPSRAKLPAMSIRLSDLLSTGGAAAVANTANSAASSTVNNGSMVPSNTRGSHARRWWASDFLQLLFRGVDMDGDEEGSGSGSAVNDRRRRINVLAEARLTVLDRSKFRLLGNSSRTDQDVAFNSRTGQFCLYLRAAVGESVIDTLVRRLRSIERLVGFLDAIRRESRVVHIQTVTLSRLVFSYSVGPGLPLSNEEKMSLTTEAVAAATAAANSCGRWDVSVDLSSSAQVHLQLERGCPHLRVADFLNNVANDPTTFSAVPFFLTATLSLHRALDRMEDAWEGLQMRNAGMLGIFPRSLDWFVVRFLIPPTPPTAGSAPTPPGSARPRVLVLDLRLKSRRSELLWQIRRLDHNSPESTGAPVPAALANAAPSPGDDDLSKVVKRVFDGSGPGWKGLLTAAVASPYPEKKPEELTSSSTPLGGSGGGNTSKPARNTGSTGIEDCLLQIDEGVRQLLAGSFAAAGNAQQRRAQALAQAQAQAQQQQQQQNNNSSIPQAQTARMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1T2</accession>
    <name>A0ABR3Z1T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA methyltransferase, has a role in tRNA modification</fullName>
            <ecNumber evidence="5">2.1.1.229</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TRM9</name>
        <name evidence="5" type="ORF">Sste5346_005791</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.229" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="95"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="290"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="384" mass="41607" checksum="2D1D77C31F21A155" modified="2025-10-08" version="1">MTADSRRPLNLVDSQTGLSQGDHHHDQGQDQGQDQGQGQSTSDDQVTVDDASHYEQTHVHEVYDAIADHFSATRYAPWPLVAQFLAAQPAGSIGLDVGCGNGKYLSGASGAPPSSSSPTGDPQLFILGSDRSPALAKFAYEKHAQHQVGADVLLADSLALPFRDQCADFIICIAVVHHLSTRERRQAAVEELLRCVRRPDVQQQRQPQLPFAANSSQTPPAPTTTTTGPPGPSFPPSCFTESSSPASSSPTSLSPLQSGRVLLYVWALEQASSRRGWAAGGEQDLLVPWVKTMRDKNKPKGKDKGGKKGKMQKQEGVDSSSNKIEEEGKKDPEAQQQPHVPPTFHRYYHLYKQGELEDDVAAVGGRVVASGYEKDNWWVVADPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1U2</accession>
    <name>A0ABR3Z1U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1721 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042332">
        <property type="entry name" value="Hsk3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013183">
        <property type="entry name" value="Hsk3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28289">
        <property type="entry name" value="DASH COMPLEX SUBUNIT HSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28289:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT HSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08227">
        <property type="entry name" value="DASH_Hsk3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="9901" checksum="59475F0895AE44A4" modified="2025-10-08" version="1">MNNQPTATFNTSRTTTATASGPAVKARQLAHLQSQLSMLSGHLADTDSLVRVTAAQAGYLRELGSWHAGLFMAASKVLGEEGGKEASREEERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W3</accession>
    <name>A0ABR3Z1W3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Unsaturated glucuronyl hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57780" checksum="D2C608C724533854" modified="2025-10-08" version="1">MGSIGNPTAVNGTTTNDITPSVLHLKAGNSATTLTDSIRTQLAELFSENITAKIARAAVEQLKDNVSIQSANINYPCVLISTFQNPPIQYPEIVSQSGVNKGHYQSREVEFWISGFFPGNIYAVLERVIRYPSSLGLSSKDATAILPVLRNTLEETGKTWSEPLRGQASRTNTHDLGFMIMPHMRPRWEFYHDKDAFDTILIAAESLASRYDERLSCIRSWDTMDWHDGVNITSMEDNFLVIIDSMCNMDLLYYAAAQAPEKRQMADIATTHALTLLTSHLRPETTASRMGYEGTLYSTVHLVNFDPKTGKIQTSRTAQGYAADSTWSRGQAWAILGYAQCFAWTGDAQFLDAACGLIEYFLYRLESAPSCVEIVLPKSGGRTAGRYVPLWDFDAPIEDPSQPLRDTSAGAAAANGMVILAQALLGHGSHVLAQRYLEAATTIVKDTMDLALAREKVQMQIGSDGALTFRDTEGERFDTILKHSTVNNNSASDDSKRHKDHGLVYADYYLLEFGTLLLRLGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z439</accession>
    <name>A0ABR3Z439_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Translocase of the inner membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TIM17</name>
        <name evidence="12" type="ORF">Sste5346_005209</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="154" mass="16115" checksum="25F7B63C7F86FF05" modified="2025-10-08" version="1">MDHGRDPCPYVILNDFGGAFCMGAIGGTIWHGIKGFRNSPYGERRIGALTAIKMRAPVLGGNFGVWGGLFSTFDCAVKGIRKKEDPYNAIIAGFFTGGSLAIRGGYKAARNGAIGCAVLLAVIEGVGIAFQKMMAGGTKLDLPAPPPQPEKIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4H1</accession>
    <name>A0ABR3Z4H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005632</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011814" description="Acid phosphatase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="50930" checksum="BE924805AC6CF89B" modified="2025-10-08" version="1">MPSTLRVASSAMLLALATAPVSVVADESVLGIYVFHRHGDRTTKSWPPTMLTALGADQVYASGNYFRERYVAANASSRISAVATDIAVLAQIAVTAPVDNVLQSSANVFTQSLYPPAGTAAQQTLANGTVTESPFSGYQYIPVNIVSSAASASGSEDSEWLQGGSGCNNAIISSNNYFSSSSYLETLNSTKDFYASLLPVINTTFTSAQDTFKNAYTIYDYVHVSEIHNATIPSSDLLTNDTLFQLQTRADQHEWGLAYNSSDPVRAISGAVLAGQILQSLNTTARAVPTAKSTARLNFQFGAYGTFMSFFGLANLTAANPEFYGIVDYASAIVFELVTNATLGDKAVDPSDISVRFLFSNGSAGVNGGLTAYPLFGQSEVTLPWNTFTSEMNKFAISNTISWCNACGNTTGVCDPSALGTGSGSSSGNASTTSSNNGGGGVSRAVAGVIGALVTLAVILGLEALVMLIGGLRVVKKNVAVAGKAASSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P1</accession>
    <name>A0ABR3Z4P1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Imidazoleglycerol-phosphate dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038882">
        <property type="entry name" value="Rcf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153:SF1">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11619" checksum="A50934F172990BDE" modified="2025-10-08" version="1">MRTSIHDEEANVAGWEAVRGAVYGATKYGVAFALLGGIGQAMSPLYRGLTIQFKVYIQMSGMVLGSMLEADSRLRLYEANMRQQRRIARHQAKIRALEEEDNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5U1</accession>
    <name>A0ABR3Z5U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="986" mass="108123" checksum="992D935A7A5AC267" modified="2025-10-08" version="1">MSNGVAPNGAAPHAGSAGGVGGVGGPAQNVGTGIGAGESSAIGVQPPRLPTDEDDEDYDWDTIEENWLQQIAEARQKEDREMVEEYNGEEELLRTELDAAVCEHNRLTEMLLQARVLVDEKKADLEWLVDEFTKRRKAVVDRRAADDFRVRAWINKGRRFIEARHRQATQATNGATPMQVDGHGSPVNGEANGSPFSFSASGSHPAKARTLPLRNGSNGVSHGATNGHSHDPASPSPLGVAASATQNAQNAHAHNVPSDYEPNADGSVSVVNTAGESVGTVMPIRPENHWIQTLLERRVQRPVEIRLGRKFTQAHMDSIYEGNDQKRSKWLSFMIQATGELQDRACQTCAKGQGLFSLCIIVGGPDFPRCGNCEWNKQGCHGASGPNRGPQASASASSKSAKQKKQPAHQDEQSHLNCGPVGTPTKQSANTLSNQGSPMALDKTDGRPSSKRGRTSQAHSQSPGTPQQFESFMVRELSPSAEASQEITADMIALRHDGMIFLEPDLMHGVPLRKISPDHAYWEPGWKPIEGAIQSKLEEWTDKLAKLKALPESSLTDKERTAVFQAGRQVNRGRATTRYLATCDFHPYQLVSKKWITPSLTHYDTLFRMVATLDELAKFRLDVTPLEWLRQRLYEIYLEKKGNFKLDRAIAKLYHDPKLAHLRSKNGFGNIGRPSAASKPRAGDAGIKPGSVDGSPEKKPAAGEKRKDPPLGDAAISTPAKRALVDTEKRPGKDSGSRQTKTKQSARSLGTAKPGTATPTTNPRVRKPASSKARDSKGPTPATESVSSATPSRAASHATDGVPASSAEAEDEDLEHDGYTTTDSLTRDTVVKKDWRVYQVKTKDLATNPQTTQYWHWVDRKQAYRSGPGGRRDFDPMFEHQVLKETEPTTGWGVFAEPVDFHLRLRELTEVAFSPESDIIVIGTREVKGIDRRGNVLAQFKRERTKRRFLAFLKKKGVPLKRTTREEIETEWNGIQAEVMAGNESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6K5</accession>
    <name>A0ABR3Z6K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARC19</name>
        <name evidence="6" type="ORF">Sste5346_004671</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="19528" checksum="0418CA6D09E4915F" modified="2025-10-08" version="1">MSQSLRPYLQAVRSSLTVALCLGDFASQTAERHNVPEIEAQSSPEVLLTPLVVSRNENERVLIEASVNSVRVSIKIKQADEIEHILVHKFTRFLTQRAENFFILRRKAVDGYNISFLITNFHTEQMLKHKLVDFIIQFMEEVDKEISEMKLFLNARARFVAESFLTPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6S2</accession>
    <name>A0ABR3Z6S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF50">
        <property type="entry name" value="MFS SIDEROCHROME IRON TRANSPORTER MIRB (AFU_ORTHOLOGUE AFUA_3G03640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="92"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="609" mass="66969" checksum="4471DC7481FFA1CE" modified="2025-10-08" version="1">MGLPKFRFNKSPITEPAAETAEATSTSVNMATVGDELKTAAPETVAPANVDLEADDLPRKDADDLPTENAQAGVQDVEAVTLTWSKPSLIAVFILMFLLYFVNAMQASILYNLTPYVTSDFESHSLLTVIGIVANAMTAAIYIPLAKMLDLWGRAEGFALMIFFATLGLILMATSHNLSTYCAAQVFYSIGFGGMTYSIDVITADASKLKSRALAYAFTSSPYIITAFAGPKVSDDYYYNISWRWGFGTFCIILPVVALPLFILLKLNLRKAKRQGMLIREPSGRTFTQNIWYYLVEFDFLGVFLFAGGLTVFLLPFTLADSAPNGWKTGYIIAMIVVGAVVLIIFGLHEWLLAPTPFLNIGLLVNRTVIGACLIDITYQISYYCWASYFTSFLQVVNNLTLAEAGYVGSTFDVLSGILLLGLGFLIRKTGYFKYLLFIAVPLYLLGMGLMIHFRSPNGYIGYIVMCQIFISFGGSIFIMIEQLAILAVVDHQHVAAVLALLYVAGNVGGAIGNTISGTIWTNTFEYALELYLPAEAMDSIEDIYNDLDFQLSFEVGSPTRLAIQEAYGYSQKRMLIAGTAIMATTLIWMFLIKNINVKKVPQVKGTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7X0</accession>
    <name>A0ABR3Z7X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Adenosine kinase</fullName>
            <shortName evidence="10">AK</shortName>
            <ecNumber evidence="4 10">2.7.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Adenosine 5'-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ADO1</name>
        <name evidence="12" type="ORF">Sste5346_004914</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>adenosine + ATP = AMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20824"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.20" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004001">
        <property type="term" value="F:adenosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001805">
        <property type="entry name" value="Adenokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769:SF3">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00989">
        <property type="entry name" value="ADENOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="11">
        <location>
            <begin position="31"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="360" mass="38337" checksum="7FE4881938559ECA" modified="2025-10-08" version="1">MATQKNFRLLCLENPLLDIIADGDQATLDTYKIKANDAILAEPQHLGIYEDFLNNRKAALSAGGAAQNTARGAQYILPADSVVFLGGVGKDKYADILTETAAKAGLRVEYRVDEKVGTGRCAVVVTPGNRSMITDLGAANHYDLEHLQSPAIWPLVQGAEAYYIGGYHLTVCPPAIMALAKEAAANDKAFVLSISAPFIPLAFKDALDATLPYLDYVLGNEAEAAAFGNVHGISNIDLADVDGTATTEDLKKIAQYMADLPKENGKRKRVAIVTHGSQPTLVAIQGETEVKEYSVRTIAKDDIVDPIGAGDAFAAGFVAGLIEGKPLDVSIDQGQWLASLSLKQLGASYPYPKQTFTPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z829</accession>
    <name>A0ABR3Z829_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004459</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF130">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTO (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="794"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="810"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1005" mass="112326" checksum="2E7D19A8E2689BE9" modified="2025-10-08" version="1">MSSQAADKKRPGSSAPSSRGSSPDSDRSHDDHDRDRSESQPGDEKGDHPPRKRQRVRLSCLECRRRKLSCDRGFPCERCIKSGTPERCTYETRPGLAPPAKNGLSQGALANFESRISALAGGLGGGPVGHGGSAGINSIGGGGVGGSYMSDAGIVPPYRRDSHRSGSGPSSMVDGDRMRRLELEVAQLKQLLASAAGVANNNNPLNKLLLAPSDGSATLRDDDSPQEKEGGRAPSPPTTFVETIYGSGGAAAMEVGDELRFFRGKEFKTRYFGPHNACMAFSELTGLCPFMKETAEEWLRPLHVHHHHSKDREKRKQDREERFSQPDPELEALLPDRTEMNVLINIYLDQFEQVYRIVHIPSFKRDYTAFWEPGAKRTPAFTALLLSMMSISSCLRGNPTGKFVGMISQSHHMAEKWINACDAWSQRQSQKHRKLVHYQIACLNYLAKRVNTMKKKRFWKASGALTQDAVSVGLHREPSHIHDSVSVYNQEMRRRIWATIQEFDMQASFDHGLPTLLSALRFDVHPPRNLADEDFDEDTTELPQSRPTDEYTFSSYQHLSRQSLPLRLQLSRVLTGPPDDLDYDQVIRYTNDITQEIDALPSWDVRAIAAAGEDGETNGNGSTAKLTPLLAYTLLHIQLRQYIIPLHQPYLKLRKTNSKYQYSEIIYYNAARDMVLLHDKLAEQGVRTLNFLREDALTLSINLCSVTMLQSRGSTNMIMVNSQHTKKLLEKCLAMKEDRVLRCGNNEPWGYSIMCAATGLLEAHLGDKTPEAAKASSAERFVNLHYKLLARQEQQTANGEGQKQTEEDQSQQQDLPQQQQLQVQQPPSQQRPLQSPQQQRRMLPPQMQQAMRQQQQMLQQQQQQQQQHNVNGNGVNGGVNGNGVNGVSDLTKVRLRPSYSPSTPALNRQQQQQNQQNSNMLSQHITPFLPMTQATSTPGVVDAAMPAPPAAWWMSNIANMSSIANPNADSTAIQAAQQVVNPDFNYELLGLNLGDLWADYSWEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB17</accession>
    <name>A0ABR3ZB17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Translocon subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SEC61</name>
        <name evidence="13" type="ORF">Sste5346_004063</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="12">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="475" mass="51979" checksum="1C383F51E4C1874F" modified="2025-10-08" version="1">MSSLRFLDLVKPFVPFLPEVQQPETKIPFNQKLMWTGLTLLVFLIMSQMPLYGIVSSDTSDPLYWLRMMMASNRGTLMELGITPIISSGMVFQLLAGTHMIDVNLDFKSDRELYQSAQKLFAVILSIGTATVYVFTGLYGPPSELGAGIVCLLILQLVTAGMIVILLDELLQKGYGLGSGISLFIATNICESIMWKAFSPTSINTGRGPEYEGAVIALFHLLLTWPNKQRALQEAFYRQNLPNVMNLLATLAIFAAVIYLQGFRVEIPVKSSRQRGARGSYPIRLFYTSNMPIMLQSALSSNIFLISQMLYSRFSENLLVQLFGVWEAKDGTAQLSATSGLVYYMSPPLNFKDALLDPIHTVVYIAYMLTACAIFSKTWIEVSGSSPRDVAKQLKDQGLVMAGHRDQSMYKELKRIIPTAAAFGGACIGALSVASDLMGALGSGTGTLLAVTIIYGYFEIAAKEGDLSGMGAVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB19</accession>
    <name>A0ABR3ZB19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="56124" checksum="E9790E1009EAEE6B" modified="2025-10-08" version="1">MALQRTVLRPLGGYEQYSSSRHSLGLYQNVITVCRYALPSSLGETETETGKVEAVKENIRHAVTTIVLEKLPALRVGIEGEDTKSPVFVALPSIDLGLHIELVNRSPGLSPKEEDDQLMRDLEKETARPFLDVATHSPWRLVVYLNTAENWADVGFAVHHALADGKSGLIFHTHLVETLNTISSEGNKTRDDTSDVLEFTEIPVLVPTQEELVKFTISWPFFLRTVWKELGPAWLKSTPVAGPYTGSRVTLEPKLKGNLRIFHLSSETVGALLAACRAHNTTLTALVHGLLLVLFARRFPADVASSFLCAMPMSMRPYIQAPPDMVHDVNRSMANLVSPHMFTYETELVEDGRAVGETDADDDDKVWRAAVAVGTSLKARQANVTDDNPMGLMGYVSDWHDWWRKHEGKVRDSTWAVSNTGSISPTGSVDAGTAGWRLLRNFYAQSSIGKDSLIGVNIGGVRGGEVSVVVGWHHGVTEDAFANLFTDDLHACLLRFGTTGYFSVPGRLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC79</accession>
    <name>A0ABR3ZC79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="33"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="316" mass="34175" checksum="3C1BCA948EF5D523" modified="2025-10-08" version="1">MAELQLISLATKPTAQISYSFRPAVSTTKPVLLVFLNGLGLPQASWVPAITQLKELRQENIPAILTYDRFGQGQTVDRDPKDEGAADPMHGHDCLSVVHDLRQLITQIIAEKLGVSETDSVPLVLVGNSIGCALARLYAQEYPGTVAGLLLLDSVLANSDFVSVFPDPDAEDFNPAILPPGIPPQALRATREGVRRVFHPDVGSREGLSRKNLRTLLPASDGPVLQGPGGSGPFVTVVGHDFEAFAEESAKMGPPKPITMAYVNPYWHRYNEGLVKITKREKSKGPLQAPNAGHFVQKDNPAFVAHELNELLSKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCV5</accession>
    <name>A0ABR3ZCV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="334"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="388"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="281"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="442" mass="47137" checksum="104D020A8F2F9E0B" modified="2025-10-08" version="1">MDGNSAADFDGTDDAEYMRNFQSIPKPAAATPNTFFANPVWGTETKLSTTTFTPGVYLHNRDTTYGYLDPHDTAGLTDWTKSVPGSLDPNNTSTMSMTPLHDQFLVTASPTEQQQSTWPIDTAGQPGACSSSSSSSSYMMATDATTIQPKILSGRVRMSAASHATSTVTGSVRQSRIAKPKSKPIGGSSSTRLPRTNSGNSASSSNSGHYLNTMDDKHLSVSSASSSASPPLEDSSSQRSRTASLFSSGGGITGLLTTGHGGNHNVTLRTASRKPKPQLAVPPAGASSSSAAGVSAGIPRTESPNSDLSGGPSSPSSPDGASGNAESLTSEERRARQNHNIVEKQYRNRLNSQFERLLSILPANQMEGAEMGRTVEFDERRMSKAEVLDLARRRIHALENEIQQLYTDRDNLRNNVATLNLAIQNGQQQKPQQQQQKMGITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCV8</accession>
    <name>A0ABR3ZCV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF8">
        <property type="entry name" value="PROTEIN ARTEMIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41289" checksum="3E3FB29F19848ACB" modified="2025-10-08" version="1">MSTFDGFIREFPDIQVDYFRNTQATASRRPLAGFLSHVHSDHLVGLDTLRSPFVYCSVATRAFVLGLEKYPCRINFAKGILEARKLTYKDLQHLLKPLPLETPTTIELSPGNSIRVTLFDANHCPGSTMFLFEDEHKAALYTGDTRLEPWFVNSLARHPCLVEYTAGMRTIDTVYLDTTFVERDVHFQTKAEGLRDLMQAVSRYPPDAIFYLRAWTFGYEDVWVALAKALRSKVHVDAYKMGLYRSLVTGGEAGRHQRVPGGSHYHLDPVAPGLVGFMCANSTHDGCLSTAEDGEHERVRIHSCEKGLGYCPAVTNAAKPIVWIRPVVCRLPHGRGEVPEVGAGGGGEDLNKEVELEVYGQDEASRLCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDP1</accession>
    <name>A0ABR3ZDP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clock-controlled protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038843">
        <property type="entry name" value="Sed1/Spi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523:SF1">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932984" description="Clock-controlled protein 6" evidence="1">
        <location>
            <begin position="19"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="12689" checksum="D0A66531BA983D4E" modified="2025-10-08" version="1">MKFSVASILALATAVSAGQNVTYTTEVVTALTTYCPEATTLTHNGKTYTISSATTLTITDCPCTLTKPVTTATTVSCTTPYNNATVSVTKGTASYTPTQSAVVTAGAGKVMLSGAAGVVALGAAILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE12</accession>
    <name>A0ABR3ZE12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="55"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="592" mass="63299" checksum="4BD0F9BA683A2FAF" modified="2025-10-08" version="1">MSGQTNSPSPSLEVKDKPLGTDNTLLQQDGVRYVEAAGNGNGEPEPRVTLRSWLALLAADLAYFAQLINLLGAGVQAKTIATHLGNPDQGAWFTATITIFTVVLAPIFAQGADYWGRKWLLTILLLFGVVGSIIVSRSTSVNMAIAGFSINGISNAGQPIFHTIASEVMPRKWRGYAQASSFSAVALGSVTGLLLGAGLNRTNNPLSNGFRTYFYIATGIYFVSAVLVVFTYYPSKTVKQRELKGQGEDSIMAKLAKLDWVGYILIAAGIVLFSLGLTWAKNPYPWSDPHVAVTFALGLFFLACLVVYETWFKKDGLFHHDLFTRNFAIACYCIFAEGLAFIASNSYFSYEVLTLYQHNALLVSTDYSIGFLTAMLAAILTGVYCSIVKDVKWITVAAFVIFTAFFAGMAALERTTAHSVVWGLPVLLGAGLGIILNVVVVLAQMSTPPHLIAAATGLIMSLRSLGGTVGLAIHQALLSDELGKLPVRVADVAIAKGLPESSVSAFVGAILGGNQTALASISGVTTDIITAGTNAKLDTYVLGFRYIWIAAAAFVALAAILSLFIRDLKSEFNMHIDAPVERKTSLTDGESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE31</accession>
    <name>A0ABR3ZE31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021582">
        <property type="entry name" value="Aim21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11489">
        <property type="entry name" value="Aim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="786"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="868"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="914" mass="97620" checksum="70B696846033BC61" modified="2025-10-08" version="1">MSAATQQPIVPPRPSKAQDTPKIPPRPARRAVDRSLSPSRDRFAPSPLDSLLSKSPNRATFNHGPSHLTSDPIDRSSSVDLPSVGQEGMEYAAVADELNASKSQAGGSRAASPEHTRTVGDDVKLHAPKPSLPAISAKQRVATVTRTDSEKAASFGIGQATGDDSTKKKGSTTSQELSSNEDALDEDEHGIPEIGRQVPMYPNAGDVQAPSPAPDAAANGGKRNHNRKKSARGFGDLPPGSYGLHGHGVIASDKLEKDYYSKHPELIEKEHTPHHSDRTQDYSMTSADLNKIVRETASRGSGIATHDVNGTPSEQVGWQAIEESTSRPASVAPKGKSNSFGSQSSATAKSGTPGISLSGPPDDNVIHVDDPNNRRKSVMFSEDESPDFDYESEAPILAEDEVARDPSAYDHEPAVEPAFERRLSSFDGEEGSSRPSSRPASIYRVSSIPQESAIAEDKAEDDYEPLFKDDNNKTGRAPSISSKSINEETAPRFPSRDIWEDAPSSVHYTAEVSTPDMPIKHEEEEGYVAHRPSSDLPREGETPAQAFARQQEELAEKELQGADAFAENRKPHKPTPTSWIKDKVLAPAGNTHAPTSSPAGSSASSLRRPQLGQRFPSRDVWEDAPESLQLQTVVSNPQEEEVPSPIESSSKPAVPQRPARKLTDPSDKAVPVVPSRPKPKTGLSEEDASKPAVSDKPKPVIPARPVRHQQPSADQEPESVPRSKPAVPARPFGGKIAQLQANFMSDLNKKLKIGPQAPKKEDPEPAEEAPEAEKAPLVDARKGRARGPQRSAPRAAAASPAAAPATSASTLAFSTTTTLYSIDPEDGGLVVTSGKIAEAEPEVEPVAAVAEPVEEKEAKQPVEEEAVKEEVAEPAEKTETIASNTAGEPLVEAKVEASSDSVEPKVVEEPVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEG0</accession>
    <name>A0ABR3ZEG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="9"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="28829" checksum="D1FEF89999FFA33A" modified="2025-10-08" version="1">MSHHVLVLGGHGKVARLLTPLLLQRAWTVTSVIRSQDQVPTIEALAPDANARKNLHVLVHSLEDLVQSQAAAQALLDQVRPDYVVWSAGAGGKGGPERTLAIDRDAATHIIDASAASSFVTRFLMVSYLSSRRAKPAWWDDENWAIAQHLNTKVLPTYYQAKVAADEALYRAAKRRGTSFAGINLRPGTLTDEPEGPFELGKLKLAKGNSSRASVARAADLLLAHPDVQTAWIDMLDGTEDPKKAVDRVVRDHVDAIEGEPVTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEX9</accession>
    <name>A0ABR3ZEX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phenol 2-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF20">
        <property type="entry name" value="2-MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="8">
        <location>
            <begin position="485"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="736" mass="81649" checksum="A50A13B364D77E6E" modified="2025-10-08" version="1">MTDTKSTSKTGVLIIGAGPAGLMLALWLARLGVDARLVDKRTDKVYSGQADGFQVRSLEILDSFGIADKIWNESNHMIEVCFWNPDETGTIRRDNRVVNGRAGLSRFHEVVLHQGRAETFFLDAIRDSYGPATSMDEDDVGAKTENATKTEKKSIRTHPRRRIAVERKVTPTSLAIDKQQVNDADDYPVTVTLRHLSESEATPTQVLSNVQDGLFRSNLDPPDEGVETQRKDPPVFVQEEVVQCKYVVGCDGAHSWTRKALGPEFDMVGEMTDYIWGVLDIVPITDFPDIRNRTMIHSAANGSLMVIPRENRLVRLYIQLTEVSVGSGRVDRSQIKPGMIMKAAKKIMSPYNIDYHYCDWWTAYQIGQRVGNHFSKLNRVFLAGDAVHTHSPKAGQGMNVSMQDTYNLGWKLGLVCKGILQPEVLSTYELERRAIAKQLIAFDHRFSRLFSGRPAKDILDETGVSMDEFASAFRQSHMFTTAVGIKYQPSILVAAAADSPPEQPADDKTETDDDVPQSTAHSTSALSTACIVGMRFPSHQVLRHADARPWHLHHKMPSDGRFRLVVFGGELTVSSPQLEKVNKLGAWLANTLLPKLPTMALMQGTTNLHGGGRPGYGLAPEKPPSIVDVLLVYASPSDSSGSAVEAPDLLDFHEVYHPFDSKLGHDYDKVFVDRPSHHDGDGRAYENYGIDRMRGVLVGVRPDGYIGLMTSLDADAGWNEVARWFQGILQPRTGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF10</accession>
    <name>A0ABR3ZF10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="54719" checksum="8EC835B470A32E4C" modified="2025-10-08" version="1">MDIQGLLSDKTYFCTTTINTHTTYSHNNNNPLWLLPHESAIVSSPAFYSSSTNAMSSDSATRQWTLVLVLTALFLSLVVVGQIIARYGAAYWAAPREITALLDSADSSLHENESYDRDVAKVARRDDKIRLGRLLGEIQRAGDDLREDLNNVLVIPREDNDSLDYSEKSEADIDIRLDLSGSRRRTTTASRQPPAHHISSSSPSPRLKTSARILWAAKRTHLEERLRRLDLLRMRFLVVYMSVVAATATAAAERVEKSAEKSAEIATTNAATAAATAARANAAAAVAASSTLTARNTSSSNANANRNASARRSSRSTSSGSSSSSDDSSCSSSSSSAANSPLMSATPSMPTSPSARSKTTADIVAASIAAAAAAAMAAGDTDDVYYPSSPTSMPGSPGFGHTHPFLRSIQQQSESQSKSTSKSQPTTPPQQQQPSPPATPHTGSTKTDDFDSLRRKPPSRRVTTLGIRPPDATPEHNHRAGWMGVVQELQRSPLLHKRHTSIEMSMTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFB9</accession>
    <name>A0ABR3ZFB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mucoidy inhibitor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02231">
        <property type="entry name" value="mucoidy inhibitor MuiA family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005:SF8">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4140" evidence="3">
        <location>
            <begin position="19"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="2">
        <location>
            <begin position="316"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="855" mass="92499" checksum="D105F95319A35F4B" modified="2025-10-08" version="1">MDAIHKQEFRVRDLPTRTVTLFPSRAQVVRDIKDVSLKPGANQITVVGFSPTVDENSIKVEGTGSAIISDIAIELLPNREIFQDIYPDSDDDDKSETEDEEDDSSDDDKDSAELKEVRKKLQALRDDVKRASEVVSSAESRLKILDAYGKMLDRKRGVEIDAGVETYRTERAKVFKDHMEGTVKVREVNEQITELGKEENKLLRVQIKAADKARRAREKAKEAKRKEKRKVLRRKAEAQKEKLRVQREREKYWPRKCYTVRITLDAPSYTPSSSRRTSISSVTELAKPVDGVAAAKDGSALADEEGGSASGPTCDLSISYVTSSAFWSPTYDLQLSTTNNTASLCFDAQLTNTTSEAWTSCKVILSTSQTTFSGLNDTIPTLVPWRVKLHKGYGYDAILHSREEVSHKSSWQAQQNALVTNQKPRRELFGVSPEEQMLGMGTHGVGNLMNDIRVAGQLKSRGNGDVDWYSMPQHQQMQQQQMMQQAPPPPGRATSGGLFGSSSATAASAFGSARAATTSFGAPAVPPPPPAPMVSRAAPSIAMGGGGAPAAMKKKMKSESARMRRRSVAGGGDDSSEDEEYNPVDDMTLGGELQPELEFQESSFEETGMTTTYDLPGLKTLAPSSTASKQRVARIAFRDVVFSHTIVAKYKPVAYLKAKLKNASKLTLLKGTAGLTLDGSFLGRTTLPRCSAGDTFPLSLGVDPAIRVAYPKPDVKRATTGIFSKEDSSVYRRAVTISNTRASAGKPVTLLVLDQVPVSEDEKLRVELQVPRGITVGGGSVAAGIGMVTATASGGSAKEAPSSSSSATRDWGTAAATLKKAGEVVWDVKLNAGRSVKLDLAYDVSAPTGEGVIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFK5</accession>
    <name>A0ABR3ZFK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP-binding domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002892</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859:SF4">
        <property type="entry name" value="BUTANOATE--COA LIGASE AAE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="45"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="522"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="68047" checksum="375C8AB0F518A622" modified="2025-10-08" version="1">MSGPQSRLGSVLRHLVGAPDPKAAQAAHEAPSPVFKHALTPTLFLERAAAIEPDAEAIVHITTNGRTLRRNYAEFADRARGLAWYFSHHGYRRIGILAPNTPAFLETIYASAAAGGVLVPANYRLIAADVAYIFDFADVDIIVADAQFASLLTEGTDCYASTHPTVPILIDDDIDTTQGELRGPFDAAVLEGLQFEAHRADIEDRGWAGLQAFVASQPGHKPLDEDDTIAIPFTSGTTAKPKGVEFTHRGAYLAALANVAEAGLNGQDDDHNNDGPDRCRYLWTLPMFHAVGWTFPWSVCAVRGTHVCLRKIDYPLIWKLLREEGVTHFNAAPTVNTLLCADPAAERLARPVKVTVAASPPTAHLFEQMTKLNLHPVHVYGMTETYGPITRGYILPSWNKLPGQQKFERMARQGHGFLTSLAARVIKTDDDAQPITAVNKKGVTTFVDVPRDARTIGEIVFRGNICAKGYYKDPAATEKLFAGGVLHSGDLAVMHPDGSVQILDRAKDIIISGGENISSVALESILVEHPDVLEAAVVAVPDSHWGERPKAYLTTKTRSGKPVSIEQQAFLDWVKHQSGISRFMVPREMEVVKELPKTSTGKLQKNVLRQWALKGTPDDVKVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG25</accession>
    <name>A0ABR3ZG25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl phosphatidyl inositol protein transamidase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GAA1</name>
        <name evidence="2" type="ORF">Sste5346_003049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304:SF0">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036762">
        <property type="entry name" value="GAA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="514"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="633" mass="69477" checksum="F266EFFE33221EC2" modified="2025-10-08" version="1">MPSLISSLVRFRRDPRLLKLPPYLSLLCILVGVASLLVLPLNSYSRRTYISENALLPGQVHTYFGGSDQHVFRAYKHEVNGLLDRSNTAINDHLEPILASAGLKVGRQNYTYRSAGETFAGQNLYAILQAPRGDATEALVLVSPWRSIHDVPNPHGVALALALARYFRRWSLWSKDIIFLFPPDSLTGPQAWVDAYHDAHDGRYVSPLPRKSGALQGAIAIDYTKADPADNDGNGSSRFTAVHIVYDGVNGQLPNLDLINSVVNIAGGQMGTGVSLQEMWRHDDGYADRLRTMLRGMLRQGLGAATGAHSAFMAYHVDAITLQPYTATALTPEGNLVIQGWQHDEMAMGRILEGTFRSLNNLLEHLHQSFFFYLLMGRERFVSIGTYLPSAMLLAANFTIMAIALWVRSGQAVPKPEAIKDVKEKKGKTAEKAVSPSSGNGAEERDLFLPLAVVTLCQALGMAPLYLFNHVSTWLLTPVFIGFAMANAVLPHFISRVLTTYYQATVQQYDLIKSFSLLLLGMFLSSLATLNFSLAFLVGLLASPLTFMRPAPRNAVLRWLATVLLNIVSPPGVLVVCCAVWKLDVGEALRLAAFGWDVWGMYTAVVLWCVWWPAWLAGSVLVLGRPAAASAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGG9</accession>
    <name>A0ABR3ZGG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation factor TFIID subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TAF12</name>
        <name evidence="8" type="ORF">Sste5346_003078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="7">
        <location>
            <begin position="731"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="195"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="591"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="846" mass="89261" checksum="FDAFBD387B3BD799" modified="2025-10-08" version="1">MNQGSPQQTAGTPGAAGVPMQQQLSQQPQQPQQPIMYRPEQMRNIKELTPQERGKYENGLRVLWTTVEESPEGSPERENARRKIQEFTPVLARKIRERRMAAVQRQQLLKQQMQQQQQGQQMPQGDAQAVAQQQLQQAQAAQGQLQNQAQAQAQAQAQAQAQAQAQAQAQAQHQQLQQQQQAQLRAANAAAAAAGNANAAARPGAAGSPPAGPQQQAQPGAAGPQQQPRPQQPPKFSDNVLQSLNLLTYLPPPAFADKPPEIKAKWQEDVRKKLGVSLTQIEMARNNINKLDANYKVRSTNNQITAEDAKAYKDRRDMMQKLLDDSSRFVAAYRKQQEQTKLFMQQKMLQQQQQQQAAGGAAGGQQQQQQRPPQQAGATAAQQPAGQQQKNVKTEPTNMQNSQANINGAIEAAKKESIAAGARQGAGNANMAINSPANNNAAGGPPNKPAPGIVQQTPIPPPVIPAAAMQGAAKQASKPPAVQTPVHPPPTPINTTLAAANKSGGPPTAGTPTPASAAAAAAAAAGRVPQTPHAATPVNAAPRALSHQKAIEEANKKRAASISNGAMPTPPSGHVASANGATPGSGAATPSGGNNAATAQQQQQAQNQSMQQQQAAMNQQQQQQQQVTAAAAAAAAANNNGAGGQNGAPTNATQEAARINTKMTEPRQMSKQLSEKAAQMPQPTALGGGLVPGRPTLTGGSGVVGGVLGQPAIAKVPAIQIDGEGERVLNKKRLDELVRQVCGGTAEGHEGNLLQPEVEESVLNLADSFVDSVLHSACRNAKERGSKVLEIRDLQLVLERTYNIRIPGYSSDELRTVRKVQPSMAWITKMSVIQAAKVTSATKNDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIF4</accession>
    <name>A0ABR3ZIF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Asteroid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asteroid family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026832">
        <property type="entry name" value="Asteroid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039436">
        <property type="entry name" value="Asteroid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15665">
        <property type="entry name" value="ASTEROID PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15665:SF1">
        <property type="entry name" value="PROTEIN ASTEROID HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12813">
        <property type="entry name" value="XPG_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asteroid" evidence="3">
        <location>
            <begin position="137"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="587"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="629" mass="69923" checksum="3616CBB32EB829DA" modified="2025-10-08" version="1">MGVPKLLTTLTPFGDRKPLDNANVIIDGPALAYHVVGLCMADPVMAATRSHPLEQPTYAQLGQAAMDWLDALCKHHNVEVQALYFDGYLPEAKRPVRLERSYRTSAQLKDVFSFYQRDNLPAFDVKGPRTGSLLPAPAFAVPAVLDALRKSRSYGTVTNIVPGEADTFCAWRAREDGHGTILTSDSDLLVQDLGPNAEVVLFRDIDLPKGEEAGDTKAAKKKLVVPTYKMATICQRLGLPVPEYHFLDSNETTCKRHMKSGKGLYGFAFELSMDPHLGTSELVDRTKQGLAMAKYPQEYIEFVEQYAFPEEFVAAVRFYHFNDLDPRVAEVAFQSVSSGTHPDSKKIEVKTLPILTFAPPLVDSCTRTNAWEISAPIRTLAYSLVQTLPAAQNMGETVREYSRMASMASRGLELELIPVEDLLKALDGFMFLVRLVRNAAPTTSGSNNELQWITLASYYDVLWSKENSKDSACLEVLRQETPSTGVLERVTWTAMHWLAQIQGTLYSLRILKQLVLFVQAEGECWVDSTSHKTQLAAKLESLEEILDTVTPLSAYPTLRTLRDLPSRLKTTDALELLATLAELPEPISFKPAPGSKKNKNRNRKRKRTGEAPPRVQTMTNPFAILDGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ29</accession>
    <name>A0ABR3ZJ29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002618</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="8">
        <location>
            <begin position="65"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="409" mass="45821" checksum="AC304B4842EB5CF9" modified="2025-10-08" version="1">MSPSAVDTVQSAEVAAVTKAAPAKAVRQPRLNDGTDPNTEKPALLTGHKDALKLSGALDQFKSFDVTPVIGREFGPEVDLAAWLRAPNSDELLRDLAITVSQRGVVFFRKQDNVTDELQKELVQRLGELSGKPSTSKLHIHPVNNAGVRQDATKEVADKGDHDDEISVISSAQAKKLYQDRFEKEFGKFSSRRQSASDQWHSDITFEPIPSDYALLRLKKLPKTGGDTLWASGYELYDRISPTLRGFLDTLTAYYAQPGFEESAVRNGFELYSAPRGAPENVGNILEAIHPVVRTNPVTGWKSVFAVGHHVKRIHGLSDDESQHFLEWFNQLIVHNHDLQVRLRWQDVNDLAIWDNRSVYHAATPDYIYEHDLGERSGSRAVSLGEKPYFDPQSSSRREALQKERQQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ66</accession>
    <name>A0ABR3ZJ66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">von willebrand and ring finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="456"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="663"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="592"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1040"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="611"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1213" mass="132994" checksum="7A4807A848E56698" modified="2025-10-08" version="1">MFFRSNKSSNGLSKEKRFRDGEISSTALRDLGLLSPTKLQPQSPSWRGDYDRPTYSSAGRSTTSFTGSSIYPEKSGNFGAPSYHSSASIASTISREAPSGRHLTTMTSDRSRTRRERTFVGSECAVCEEPLEHTLRGERILQFSCTHVSHEACFYEFIREFESQYCPTCNAPLHLDTSRGGNVLDIEKITNLVRSVSVADTRSITTGTPTPNWDEQTTRPPSRGSNQRPAVMSTSSAGMSTVHHNHNNHNNPRDSTRDSTRESGRDSSARGSYRDREREREREPSVDRYVGGANSRHGRSDSEATGVASSGGYPETTQSGGPRRAHDYDVQAMETTLASPRTITRNPIPAPTVTVRSEFPTISRSRQQQTLTCLITIEVPDCKWRADPEDLQSSSSGTPQLPPPSTSRNTNGDENFGRQSSPERPAPRFYPYESPEVLEEMTENLRNRVDNWHGLDFSRFGKLRLYGTLRVGKDKVSWQELECFLFAEMLICVKEKKNSGNATPASQQQHWEETNGAPVRKTTRCTLKGSILIKKHLNEVTETGTIDENVLTLSLSVAELPQFHLRFDNRNQLKLWQQALLDLNAIETSPVRSPAYDRGEFSETEEEDWQQRTPGSSRPQRVSSLASSWGGNKSITTAATEYTSYTKSPLTPAPTASIHVPIDVVVVVPISSSMQGVKINLVRDALRFMVHTLGERDRMGLVTFGSGGGGVPVVGMTTKSWPGWSGVLSSIKPVGQKSHRADVVEGANVAMDLLMQRKYNNPIATIMLISDASTSDADSVDFVVSRAEAAKITIHSFGLGMTHKPDTMIELSTRTKASYTYVKDWMMLRECLAGCLGSMQTLSHQNVKLKLKLPEGSPAKFHKISGALQITKRATGRDAEALMGDLRFGDKRDILVQLVILPDNSSQEQLPQDAWETIVSGLEALGGPVDQDEPRTVSVEEVPLIQADLSWGDILRDGTVVQMPRPSLLAITMLPPTSQHKSRSWQNTPPIPPHPSIVQRRMELLTSDMLTRALTLVSRGQHERAHTLLNETRSILKGLGKGGLPPVPPLPGTGKNGGTSVPTTPHPGSEGSPIMQIGTPDRKHTPSPTASATSVTASGFPLSNAMLPRTRSNDALGNGMGTTAGIDAKTVAALDAELEASLEWINHPAVFGRDSRKAVLQAIGVISSQRAFTFRTPIEGLWANRVTGVKKLTEKSREWREEGGGEGGIMEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ71</accession>
    <name>A0ABR3ZJ71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UFSP1/2/DUB catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="3">
        <location>
            <begin position="419"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="203"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="664" mass="73110" checksum="9D4596429803FF39" modified="2025-10-08" version="1">MKHVEDAHPEDNCPPQCSSGSNSRLGSSGPRSSHDYDIRVNSNSNGNGKAKAAYVKPRKKMGSSSSSRPASVGAGAAPITGAASGVATTSVVISGLPEDSDSMSDNDDLRNVYDDSQFADCTVEGCHESVLVSEMAYHVDLHAALEYPEVPVVDDNDMISKGKDNAKSLAAAAPRKSANPPRTRTRALNFDGGAQGMSSTRASSVPPVQRRSQRSSSRMSTDSAKSVSAVKLSGATESRRAPAPAPSPRDDSRERHRERREHQRNQERGRGRGRVHTGELGLSSLGQNSGSHQTYLSHKPSTTVRSFLAKFSGFDPRKHSSSDEKERARGDRDKEKDKAVIPLVHRHRHSSSTKNGTAKTMAPVSEVPKRLGKAELGKFAMEDRMPDALAVYLKKEWGVRHEGMIPFLQGLLEQNPTTEYAYLCDPCVQHVSRLPKEGGFCGYRNIQTMTSYIIGTKFPGHDAFLKDLPSVFDLQDMIENAWDQGINSRGRIETGGIRLTRKYIGTPEAVALFQSLNIPCSINAFKHKTPEKSRDSLLRDVEHYFSKGFYQPGAKVRATTLPPIYWQHPGHSLTIIGIEKTTTGEVNLLVFDPIFRNGSAMARFVSRQQRLPDQLLRPYRRGTRYLSRYRAFEILKLQPMAKDYDYELPVEKSPTAPPAAPPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJC8</accession>
    <name>A0ABR3ZJC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="749" mass="80410" checksum="E9E66055A103F416" modified="2025-10-08" version="1">MEANGDSLVDTKGGLDQHHDQDDGPSSPYRPVRNIPYQLRDHIRVFLEEKMYGEAIQLLTSLAAAGGSDGLNLLPTATTTSTPTTETPIWLPPPSHLAVLASLAIHPAYTTRTQDGTDLRVAGHAMQYLRHVLTVAGPVGAEMATAFAYRDARGRCPSAAATAAARARARAAGGVTNRNGNAPQTEDGRTGRPQRQLRASAGRASLKSGDYVDSQTMSWSDDDDGNWGAGGGGKKKTTRKSKSSSRRRGGDRDKDGMNMGSQDGWNDGASNGGINNYNGDDDDDDDDDFDAEDNDEDAVSGRMATRDGVWRRGQNFWRVVAWALGCSIQEPARWRCWQPWLTLMVDVVEADLAERLADDEDDLYDSLLFQYLSEDGGSGGSSSTTHLRRIAAAILADGSQSNLAREVFDKETVLTGAVAGNTSTSDAASNPTFDRQKRVLDLDNDKFGDYSDDDESAPSTPESSPSPSPSPSNKKKVKPAPTKTSKRGSRSGTHEASTDAVGTHPGFLESLPLRRRLFNLVALGSVHFASAFATTDAVYRSFAEVLREAEISVFAAFVAAPSPAVPSSHAGLPVSPSHINPPTPDDIFVGLLRHILFTYLPTSAPKPHIVDPITARATSAVAAVSPRVLERCFLPFAANTVLLSANVRMALTLESLFRLVWQPTAPSQSADDYPEDLWSPALQVAAETGVQARENRARSSASSTTKQKSALAVEAYGRDLMQRSGRRLLAMVQLARMDAGEPEMVIGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJI9</accession>
    <name>A0ABR3ZJI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uracil-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">URG1</name>
        <name evidence="3" type="ORF">Sste5346_002547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="2">
        <location>
            <begin position="100"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="1">
        <location>
            <begin position="330"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="460" mass="50385" checksum="E2C5354A1EE88B01" modified="2025-10-08" version="1">MTTANGDPAASSGPVGTEHIAGILEQMQKSQAELLAAVKSSIATPTPATASAPASALSPAALSAPVTIANPVSEPPVEADNALTSSPTLSSSPKSTFTSRIILTTYPNQIGINPFPMNWGAENPEERGPIVVSRAPSTIRRRNAHGGSYSIYYALAVASQQLNADHRPDFTNTEPAVNIGPFPQWYDKKKIVAMDPWGHLPQTLFKDVMDKDNVDIRPTIAVTKAHMRLPELEDSVRKGRLVPDGKVCLNDKGELAVTKFAVEPVWYLPGVAERFGIDEGTLRRSLFEHTGGSYPELITRGDIKIFLPPIGGLTVYCFGDPAKMSDASVRLALRIHDECNGSDVFGSDICTCRPYLIYGIEEAVKEAQNGGSGVVIYFRKEGRALGEVTKRGEDRASDYFKRTENIAGVKDMRFQALMPDILHWLGITKIDRMLSMSKYVYLKDPRQRGSFIRYLRNKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKE6</accession>
    <name>A0ABR3ZKE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="46701" checksum="E10287E729272FDF" modified="2025-10-08" version="1">MTDSTHPPPPHPATAATIAPLPLLPLPTPPTAVAVLPSPAPSLSKAVTTTTANMTSPPEAPAPAPAQEMVSTTKRKRDDDDEGDSQQLQQTHQHLQISPPPRPILPRTTTIALHTAPPRPTTSSPPTSSTPRFSFIAPRPAAASRNEIDGTPPYPPFVQTSGLAFTPFVAGATLEAQDGGANSPRTHVANRFNSLAIAPAGRTEPGAEGEGSFPSEPAAGDATDDAEIKLPLHKRMKRDDQEMTETATTEPSSSPDRIITDPLRASLTWQDDEITVYDPNDADDDGTGVNGIGFKPTPAMAHARALKRRQQLAAYRKREEREARARRSLQRTRGNQAARAARQEGSGTEGTGSDGPSSLSATELSSSQSQSEPSSSQPDAFGIVDPRTPRSLANAAAAAALSSPPATASPSVRRVRFLETGPVTIRFKEPDAVPSPSPTSIMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKW7</accession>
    <name>A0ABR3ZKW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="373" mass="41057" checksum="68610B666A321DB7" modified="2025-10-08" version="1">MNNNNFHQYPHSPPPSYSWQQSAPFASPTYGAIGTSFNSYGNGETGRNGHGSFASNEDNNTRHSTHQPLAGSPSGPTNSGGDATAASMPRQSSFSPIDPMDDFNDISPRLSDVSIDSNHDRSTPPSSLSASSAQDRVHNGFDSSSFRNGSIATNGTGSSGATIVPGMAGGLPLASRSDGRPRTSRRGVNRDEFDGPHQFLPRPTQQYIAMQERELPHLPTNLLVQEQDSVLSQVNDRLSQCAFDFVARYQFPVPLTQDMRPVARPQDREWTEWVQLLKRLATKRRIPARVLYNGQIKQFVTILENSLEMRHAARHQSRPLKDDRNILQLISAGIQVAKILKDAPAMSFLDQLYIATDQQIQDRSASAAARFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMF6</accession>
    <name>A0ABR3ZMF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeodomain superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CUP9</name>
        <name evidence="7" type="ORF">Sste5346_001757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="325"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="327"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="487" mass="52927" checksum="030296189E98CC52" modified="2025-10-08" version="1">MTVAVMRGFPTTHSAFESSSPSALRDGGNRLPQHQGLPTSRSTQEPVSLSLPPIREALSFFYAGPPDSTAGSSRATSVPSGPQRLSHSPRTANESLAGSRDNTYVLSNESEREREMRMSFDDAEREREERYGQNQIPRGYSSGMPYHHLDHHGESSGMTEGAATASVGSSPPSSSAYSTIADSEAWSSRRYTDSASHYPGSGRPSLPALPHMMDDHHAHHQQSRPSHASHHSHGSGPGPYQQHPSRAQSLSGGSIGSFDRAIFPPSASSSGAGPSSYDHRHSSRSSSFNRHPQDTYYSSNDYRARGVSSSHGGMMAGVNGRLGDSKQRKRRGNLPKETTDKLRAWFSDHLHHPYPSEDEKQDLMTQTGLQMNQISNWFINARRRHLPAMINNARAVNGAMTGGHSSGSGAMGSAMGGMGGSMDAGRSGASAKGYMPANERMYPSPERMYGSFERPLEPRPSSIYTGSEHHHHRVDPRRNSPSSDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMM8</accession>
    <name>A0ABR3ZMM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="38105" checksum="F8FA84C559CBDD50" modified="2025-10-08" version="1">MPSTQDPNALPWDPHNDIFPARGELPHITHSEVEKVPEGAAWVWGYDDQLGRLNLLTPERVATAAREQIQTGQSTRVDLPLDVPKHPSWQREPFVHHVKVIVGEGGIGHDDTYSLNTQSGTQWDGFRHVSSGDTGLFYNGTTANDIQQSTEPAGIHHWSTKALAGRGILLDYCAYADSQGIKYDSASSHAISYTDLVACGKHQGVDIRPAHQGGDIHPGDFLFVRSGFTQDYFNRTDAENEAIGNRSSPQWAGVLQEPDMIDWLHDCYFAAVAGDAPAFEVWPTTQSYKLHEYLLPLWGCPIGEMLDLEGVAALCREHKRWTFFFCTAPANCPGGVGSHVNGSAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMR1</accession>
    <name>A0ABR3ZMR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Integral membrane protein DUF92-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="38861" checksum="3611EF80DD8F9F6D" modified="2025-10-08" version="1">MKPVIAIPATLALVYRAYSKKSLTASGIFVATLTAIAHAAHPWNLPFVLLAVFFLAGSRVTHVKEKVKSQLTLPARGGTNAEGGEGPRTHVQVLANSLVASVLTLLHAYQLHQRKQVLLDLHAGGDTAIAAAANTDLETLGSLCYAWRGDLLVIGIIANYAAVAADTFSSELGILSRSTPRLITSLTLRKVPRGTNGGVTLGGLAAGLLGSIVVVTAAMLFLPLCTSDTTRNPLLFGTAAASVSAAWTAADRRALMGFLVLWGLLGSVLDSVLGGLLQRSVRDTRTGKIVEGEGGIRVLVSDEHHSSAAAATTKTEKEKERPASRVVENGWDLLDNNDVNFLMAVIMSVSAMAVAGWYWNVPLTSILKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNV1</accession>
    <name>A0ABR3ZNV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="12">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">TOR1</name>
        <name evidence="18" type="ORF">Sste5346_001360</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 12 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 12 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="16">
        <location>
            <begin position="1252"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="15">
        <location>
            <begin position="2161"/>
            <end position="2481"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="17">
        <location>
            <begin position="2587"/>
            <end position="2619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1574"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1841"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2511"/>
            <end position="2534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1316"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1574"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1841"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="2525"/>
            <end position="2534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1902380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2619" mass="293566" checksum="C86F74F82E087589" modified="2025-10-08" version="1">MSSPQVSAELNSDALIKELRSKPITDDARRRAAQQLRELVAVAQRDLSPEIFQGYWASVQAKISSLLQGDNTIDKLGGIYALDAFVDFEGVDATVKYTRFASALTRLMSGKDINCMQPAAIVIGKLCRPGGGSLVSSLVDTDVQLALEFLQDGSSEERRYSAALLLREIARNAPTLMYGKVNDILEWIWVGLRDQRHLIRVTSAEAVSACFKIISERDVEMKNNIMDKMYNEAHHGFKMNTVESIHGSMLVLKELLEQGGMFMQHRYTDSCEIVSRYKDHRDATIRKTAVLLIPDLAIYAPTQFSENHLHQFMIYLSAMLKREKERNDAFVAIGSVANAVKSAMAPYLDGILIYIREGLSVNARKKASVDPVFDCISRLAVAVGQTLTKYMEALLDPIFACDMTPKLTQALVDIAFYVPAVRTTIQERLLNMISLVLSGEPYKHLGAPMSQGAGVLSAPVTTTTSSKDAGKDAAAIEQHKSEVKLALNTLGCFDFSGHVLNEFVRDVAMRYVEDDDPDTREAASLTCCQLYLRDPIVNQDSYHAMQVVGDVVERLLTVGVSDPVPHIRYTVLNALDDRFDRHLGKADNIRTIFYALNDEYFPIREVAVRLIGRLTRENPAYIVPSLRKTLIQMLTELEFSDVPRNKEESAKLLSLLVQNAQMLIQPYVHPMMEVLLPKAADPTASVAATIIKAIGEICTVGGEEMLRYKDRLMPILVDALQDQASMMKREAALRTIGQLASNSGYVIDPYLDYPQLLDLLQNIIRGEPQHAMLRQETIKLMGILGALDPYRHQQVEERSPEVQRRVDSTQTTDISLMMTGLTPSNKEYYPTVVVNALLGILKDHSLVQYHQDVISAIMSIFRTLGLECVPFLDRIIPAFLQVIRSSSPSKAEAYFSQLATLVSIVRQHIRNYLPCLVEIMQEYWNSSPSLHSTILSLIESISRTLEGEFKIYLAGLLPLMLGLLEKDTSTRRQPSEKVLHAFLVFGSSSEEYMHLIVPVIVRTFEKPNQPTFLRKMAIETIGKISRQVNLNDFASKIIHPLNRVLASGEPSLRVSALDTLCALIHQLGKDYLHFMNMVNKTIQQQGIQHANYELLVAKLQKGDVLPQDLTSETRFADQLDEVSFAEQPTKKLEMNAIHLRAAWDTKGKSTKEDWQEWLRSFSTTLLNESPNHALRACAALGNVYPPLARELFNSAFVSCWSDLYENYQDELISSLENAFKSENIPPDLLGLLLNLAEFMEHDDKALPIDIRVLGREAGRCHAYAKALHYKELEFLQDQSSSSVEALISINNQLQQSDAAIGILRKAQLYSDGIQLRETWFEKLERWEEALDFYENRERELPENAITPIDIVMGKMRCLHALGQWDALATIAGNTWANSSQEVKRLISPLATAAAWGLNKWDLMDMYLQAMKRHSTDRAFFGAILALHRNQYREAAICVEQARQGLDVELSALVTESYTRAYQVIVRVQMLAELEELIVYKQCDAKKQESLRRTWDRRLLGCQRNAEVWQRMLRLRSLVVTPMENMQMWIKFANLCRKSSRMTMAETSLQNLIGNEDPLEYTIPYWMDADVLRERESKREREREREYHRRRAARESMAGNGLGDENGRDRRDFRNGRLLYENSGHNGNNSNGNNEMLLLGGNGGPNGMGGAMNSAPHDDYPRAPPPPPAQVIYAVLKYQWDRGQMAKQKSSGISEKSLDCLRKFTIDLSYRLEGARQQYQLQNNVMNNTGPMTALNSVGGGAGNAGNMANVVGGGNQLNSESQRMLQEQTTLLAKCYLRTGDWTVALNRNTWRRTHVHDVLTNYAHATQYNPKWYKAWHAWALANFEVVQYLTAANANANGSTNGVPNSQSANGAHPPVGGVPRTASVSQNGPPGPVDYATVLEHVVPAVHGFFQSIALSKGSTLQDTLRLLALWLTHGGHPDVNAAVTDGFALVNVDTWLEVIPQLIARINQPNKRVQQSVHNLLADVGRAHPQALVYPLTVAMKSAQNSRRSRSAAQIMDSMRQHSAKLVEQADLVSHELIRVAVLWHELWHEGLEEASRLYFGDHNIEGMLSVLQPLHDMLERGPETLREISFTQAFGRDLSEAREWCKQYEVSHDVSDLNQAWDVYYQVFRRITRQLPQITSLELAYCCPKLVTARDLDLSVPGKYKSGQPVIRIMSFETTFTVISSKQRPRKLNINGSDGASHTFLLKGHEDIRQDERVMQLFGLCNTLLSMDSESYKRHLNIERYPAIPLSQNSGLLGWVPNSDTIHVLIREYRDCRKILLNIEHRIMLQMAPDYDNLTLLQKVEVFGYALDNTTGQDLYRVLWLKSKNSEAWLERRTNYTRSLGVMSMVGYILGLGDRHPSNLMLDRGTGKIIHIDFGDCFEVAMKREKYPERVPFRLTRMLTYAMEVSNIEGSFRITSVHVMRVLRANKDSVMAVLEAFIHDPLLTWRLTNAQSPAGPNFQSERELALAGPQAGGAGGAGGGGRARRPSVLDSHVAPSELLAGGGADANGVGAAVGVVGGPPGARGRARTNSSLMPPNANGVNGANGTNGDTSIANTNGTMNGYGQMAAPDPVELQNARAVEVLDRVQQKLTGRDFKIDEELEVDMQVNKLIGEATRLENLCQHYIGWCSFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP01</accession>
    <name>A0ABR3ZP01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acetylserotonin methytransferase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="761" mass="81243" checksum="55796DA51899B220" modified="2025-10-08" version="1">MSGTTPSGGFSLFPSTGRPPSRTQASRPRAASPQQQQQRLSPEATGHFPQTIGEAVTAEVQIPAPVVVADISRRSPEHTSTEDDIARNSSVRSRSSIAKVRLSMYDDGPPIDDDPPPPMPSGAATLAELQLQQQSTQGSSSAQQQRHRPPALRSIFPQYNPDVSLDEQNYFPTQTSPTRIPRGVISRPLYSPTTQQPEQPNQHIDAAAAARTTSPAPVYAPSVNVASPARQRPTVQITPPNNPSPAPVQVPMHSGPVPVGAPRGDPPALPKPSTSDDLRNLWKVANGWKAGPSEGRVFCLRMSCDRDAPIYRLSSANHQPFYRLRLDPTSMSAYVTLSRHDPARPFKLESSKNNHNSSSDADVAGSGADGGGSSRNSVLDMGVSSGSIAGGSGIQSVESSAAAAAAAHNARFDGSKNWQVAMTTTLEEEARRHQPQDGLVALLYPSAATRMALERPNDAAMVATAERECARLVWDDDTSTYFLVHPTLALPFAVTIERSSTWSRTAYTLEHRESPQHLARLTRDGTGAGFLEVDTGIASKIDAVYLVDVVVTALLLVAHNDGQFAAVEQFAPPPDSRLAMHQHGLGQHNSAHNSLVNMVLNGAMGRGSTSRLSMRDGASGGGGKRTVEKKSSRLGFGFFGGGKKNKSSSKGRPRMDDFDLDLESQTSIDLSGKMFEMGPVGNGGGGRNIGMMDNGGTGGGMTTKSSKKRSRKEKDEDKMPGCLRLIAALFKCCFWCVAMVVRAILAIVGGCFKCVTNEKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPI6</accession>
    <name>A0ABR3ZPI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycerol channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FPS1</name>
        <name evidence="10" type="ORF">Sste5346_001374</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="36429" checksum="7E73FE8BCDDAAEF9" modified="2025-10-08" version="1">MSASDDTIEVRQKNTSVDHESKDGMNNHEAVNAEFAGEYASEDDQPLAWSRIREYSQDFFSEFLGTMILLLFGDGVVAQVVLSKDVKGDYQSISWGWGIGVMLGVYVAGKSGGHLNPAVTLANCVFRGHPWKKFPVYFLAQLTGAMTGAAIVYGNYRSAIDQFEGGNNIRTVSGDTATAGIFCTYPAAFMTRTGMAFSEFIASTILQFVIFALTDANNIGAGPLTPLCLFFLIFGIGACFGWETGYAINLARDFGPRLVSYMIGYGHEVWSFGGYYFWIPMVMPFLGCLFGGFLYDTFIYTGPSPMNTPWLGLKRLVHPRKTRSPWVVSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQB2</accession>
    <name>A0ABR3ZQB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cdc27</name>
        <name evidence="6" type="ORF">Sste5346_001267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="435"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="484" mass="51222" checksum="41E4E885BBE464E6" modified="2025-10-08" version="1">MSSPKEFLADEVLVEKKVITYRYLSRALKVHVNIAKKALFDFHTAQNAKQPGSLHATYLLYGTKAGEGTSPAQNGGAAEEDIDMEDGLLPDYLQSDKVPTTVITLVAEGNLESALAQYESLDAIHVYSVSPQPITDLQQLADTTRQLCELRGSAAPEDSPKTFGTIPNSHVRRRQRKGQAPIAAAAAAPAPAATPSSVFAKTTPKPAAADAPGPKSIWNKVNAAKENKDDNKSSAASSKPAVADSATPETKDAKKPIAAASSSAAAPPALKRAGSSGGGGIMQAFAKGANAPKPKKREPLPAVAKKPAEEDTTMGMSDSGDDDDNDEDVIPKAQQVVGGKSRQERQEELRKMMEEDDDDDDEKDEDEREDTPMEDVEEEKPAEPTAPAKDEGPSEVVTASSGDGRRRGKRRVMRKKMIEDKDGYLVTIQEAGWESFSEDEAPPKAAPVSAAPAASAASSSSSAKAKKPAPKTGQGSIMSFFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQM3</accession>
    <name>A0ABR3ZQM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">short-chain 2-methylacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="11">1.3.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_001455</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF1">
        <property type="entry name" value="SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="16">
        <location>
            <begin position="68"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="15">
        <location>
            <begin position="180"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="14">
        <location>
            <begin position="287"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1902474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="442" mass="48283" checksum="8D7FD41FDB38918C" modified="2025-10-08" version="1">MSSFLRALRPALRMGQASAISRLATAAPRRALPSRIVAAQASRSFSYTPARRDDDVPHLPIMSLNELESSMQEAVQKFANEVVLPKARDMDEAEAMEPEVIERLFEQGLMGIEIPEEFGGSGMNFTSSIIAIEELARVDPSVSVLVDVHNTLVNTLFTRYGSPAMQKRILPKLATESVGSFCLSEPVSGSDAFALATRATETESGYRISGSKMWITNSMEADIFIVFANLDPSKGYRGITAFLVEKGTPGFSIAKKEKKLGIRASSTCVINFDDVDIPKDNLIGEKGQGYKYAIGLLNEGRIGIAAQMTGLALGAWENAARYCWNDRKQFGQLIGEFQGMQHQMAQSYVEIAAARALVYNAARKKEAGEDFVKDAAMAKLYASQVAGRVSSLAVEWMGGMGFVREGLAEKFFRDSKIGAIYEGTSNIQLNTIAKLLQKEYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQQ6</accession>
    <name>A0ABR3ZQQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flavonol synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-haem dioxygenase N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="213"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="41506" checksum="8A627F4C24A339FB" modified="2025-10-08" version="1">MAAAVQAPPQATEAPSLAYKQVPETEYDLEWAQLATLDISTFDQPGGKEALAKQLEAAIQTIGFFYIVNFGLSQEEVDRQFAIGKEVFELPTDEKLKYRADLENGGYNGYKPLGLREVTPGVHDNTEIYNIPKFIPAHAERVHPSVINDNKPEIEHFARHIHDNIVGKLLVLFAIILELPEDALTSHHRYDQLSDCHLRYMKYHRRSAEDNAKLENVWVKGHTDFGSLTLLFRQPVAALQVRGADGGWRWVKPLAGSITVNVADALQFLTNGFLKSSIHRVVAPPPDQAHVDRLGVLYFVRPEDALELRPVQSAVLARLGYDVNEDEAAVGITAGEWVKARVKGNIGKDGKRLPLNGLEQEVIKGKSAKYYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR07</accession>
    <name>A0ABR3ZR07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GRF zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="335"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="7">
        <location>
            <begin position="464"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="60145" checksum="6EC2E45A9345F719" modified="2025-10-08" version="1">MDAFVTRQKKRKLGSPSPPPEKQSTTTTIRYDAPLKEPKLDTDFASFNDGEEEESTEVKLAMLASLIADEDTDIDQDMLLDLLMAHEGSVEAAVDAFHSRLDKWRNSKKKLKLEGGSVGSSVIGQQTSLRSLFPQTSSSSTSPEKKTTGYATTLLSRRGRTLNLYDPVDVEAHTPCTLVHNFLPPDLANDFLREMLAEAKTFGDPYTFKLFDQVVSSPHTSCFYLESATEAKEATARRSAGTSSGGGGGGGYHPAGRPPLPQDKPNDETFVLNTDTHEGYRYNGSRLSDIRTVTPHMARVRPLVEAAVNKAIQQRISTHYPSGRKLRYQNPRPWRPNAAFVNCYNGGQESVGWHSDHLTYLGPRAVIGSMSLGVAREFRVRRIVPRDPTKETRDAKDDDASGQISIHLPHNSLLIMHAEMQEEWKHCVTPAPSIDPHPIAGIKRINVTYRDYRADFHPNYTPRCRCGIACVLRVVQRKLENHGRYFWMCHAVNIPDREGCTFFQWAEFDDDGVPVWKTKEKEIESTTKAAQNDIVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR61</accession>
    <name>A0ABR3ZR61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uridine kinase</fullName>
            <ecNumber evidence="5">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">URK1</name>
        <name evidence="8" type="ORF">Sste5346_001269</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="7">
        <location>
            <begin position="254"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="450" mass="50513" checksum="C5BB0E0EC72BC2B0" modified="2025-10-08" version="1">MTSTPKQIVSQARYAPPWVDLSIIGIAGSSGSGKSSIARSIVSQLNLPWVVIVSMDSFYNSLDPESSRKAFLNEFDFDAPEAIDFDALLLVLEDLKAGRRAEIPQYSFTEHRRLEGTTSIYSPHVVILEGILALHDQRILDMLDMKIFCDEDADVCLSRRIIRDVNERGRDIQGIIKQWLTFVKPNFVKYVDPQRKVADIIVPRGIMNKVAISTVVQYIQQKLREKSKEHQATLTRLQREAKEMPLSNRIVFLPQTPQLRGMNTIIHDVETTSEDFIFYFDRLSGLLIELALNNAAFAPAVIQTPQGNTYHGLKSDGIVSAVVLERGGSALKTGLQRVIPDCRLGHILIETNVRTGEPELRYQKLARDIDTHATVLLLDAQMSSGGSALMAVQVLLDHGVAPERIVLATYSAGRMGLQRLTSCFPAISVVVCHLVEDIEERWIERRYFRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR89</accession>
    <name>A0ABR3ZR89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SEC23_1</name>
        <name evidence="21" type="ORF">Sste5346_001140</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Cytoplasmic vesicle</location>
            <location evidence="1 15">COPII-coated vesicle membrane</location>
            <topology evidence="1 15">Peripheral membrane protein</topology>
            <orientation evidence="1 15">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 15">Endoplasmic reticulum membrane</location>
            <topology evidence="2 15">Peripheral membrane protein</topology>
            <orientation evidence="2 15">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Golgi apparatus membrane</location>
            <topology evidence="15">Peripheral membrane protein</topology>
            <orientation evidence="15">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01478">
        <property type="entry name" value="Sec23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 15" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 15" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="11 15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="17">
        <location>
            <begin position="60"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="18">
        <location>
            <begin position="128"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="20">
        <location>
            <begin position="401"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="19">
        <location>
            <begin position="518"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="16">
        <location>
            <begin position="635"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1902697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="768" mass="85572" checksum="6010D39BF971437C" modified="2025-10-08" version="1">MDYEALKEQWSEVEDRDGVRLSWNVFPSTRMEASRLVVPIGALYTPLKEKPDTPLLQFEPVTCKQPCRSVLNPFCQVDVRARLWVCPFCLSRNPLPPHYKDITANAIPPELHPSNTTIEYRLSRPAQNPPIFLYVVDMCQEEDSLAALKESLVMSLSLLPENALVGLITFGTMTQVHEIGYAECAKSYVFRGSKEYTPKQVQEMLGLAQPVMRPGMQPGRPNMGPASRFLLPVQQGEFQLTKALEQLQKDPWPVANDRRSLRCSGVAISVAVSLLESSFQNSGARIMVFTGGPATEGPGMVVGPELREPIRSHHDIDRDSAKNYKKALKFYDNLAKRTAHNGHIIDIFAGCLDQVGLLEMKGLSNSTGGHMILTDSFTSAMFKQSFVRVFEKDGDDNLLMGFNAVMEVLTTKELKVTGLIGHGVSLNKKSTSVGETEIGMGNTCAWKMCGIDPSASYGIYFEIAQGGPSQIQQGPQKGMMQFLTYYQHSSGQFHLRVTTIARNLSGPAGDPTLAHSFDQEAAAVLMSRIAVFKAEVDDGPDVLRWVDRMLIRLCSRFADYRKDDPSSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNHEDVSNSLVMIQPTLDSYTFDQDGGLPVLLDSASIQPTHILLLDTFFHILIFHGETVAQWRKAGYQSQDGYENFAALLEQPKEDARDLITDRFPLPRFIVCDAGGSQARFLLSKLNPSTTHTTGAYGGVGAQTAQTIFTDDVSLQTFMDHLMKLAVSGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRE2</accession>
    <name>A0ABR3ZRE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lsb6</name>
        <name evidence="11" type="ORF">Sste5346_001347</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039756">
        <property type="entry name" value="Lsb6/PI4K2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="10">
        <location>
            <begin position="188"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="333"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="460"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="677"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="744"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="696"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="757"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="777"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="805"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="910" mass="100485" checksum="49407D016460B188" modified="2025-10-08" version="1">MPRPPTTGYERLAQADRFSDDSDDDEGAAAAGLASLQSSDAAAALSGATETTRSRYASITGNQPRPAVGMTTGGHDRRASYQHNNYRRRRANSGVDLKAINARLERWADEIANKFKRHQKKRGQEDEGRLEIHYSVFQAPEGVRPASAETLARTAAGAPDAVGVPDSVITEAEFESIVDSVRTAIREGTHPRMITQGSSGSYFARNPEGKVVGVFKPKDEEPYAAGNPKWNKWIHRNLFPCCFGRACLIPNLSYVSEAAAYVLDNQLRTYMVPYTDVVYLSSKSFHYPFWDRYSHSRNRKPLPAKPGSFQVFLKGFKDANIFLRENPWPDQYHSGFRTSDRHRNSRTGRWADNCRPSSRQVSKSANGSNRRSRSSGAVGGDQSDGADFSDYDENEDSSAASTPSPDNFVWTENLKQSFREELEKLVILDYIMRNTDRGLDNWMIKVDWPTQAVSITSEPMHLNMDGAGGSVNGSPGQSPGASNGPRPVDLSQRPERGNRARAPYRAQKPMDASTPPASNAPQPNIHIGAIDNSLSWPWKHPDAWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLLTSSAWWSQTQLALRRIFQMDPDFQERMFERQIAVMKGQAWNVVETLKTPDHGPLELTRRAKVCVWDDLVEVPIAVPMRATSSEIRRRNEFELTRAMEEEMDIGTTGGGAGEGRSGGKKAAKATTTSANANGSYFDSLDGNNDAEDLLINATSPLPNPGRFELTKELVAEEDESGEAAGESSKSPPATSPVSSQLLNAESPNARGGSRASASASASASASRQKVPQHQRRYSYTTAASRRNSNTIAQQLYGERHGGAGGGSGSNSMSNSYYLPNSQPPRHHRAASLDNYFYDDRADEDVEGDLGYAAAEGMENNRRRVIVERLEPVKSKNPVFTWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS04</accession>
    <name>A0ABR3ZS04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Regulator of gluconeogenesis Rmd5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16652">
        <property type="entry name" value="dRING_Rmd5p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037683">
        <property type="entry name" value="Rmd5_dRing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="8">
        <location>
            <begin position="182"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="385"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="7">
        <location>
            <begin position="385"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="49138" checksum="47467C66233CBB35" modified="2025-10-08" version="1">MADNMPTLRNDLSMVARKARLTSAVEDVDSIIARLLEAREKIAAAEQDPHAASLILTKLQNPIKEGFETVNNDLKAVSKTQKEFGKALDRSFPITPLPTEYDVMQKHPALINRAIAMHLLRQGHFDVSRVFMDEARDIAAIDGNDGEDDDDDRDDASMTNGEVEFDGHGNFTQTESIYLQQKFQRMYSILQEIKAHNLAPAIEWARENSEDLEERGSNLEFELCKLQFIWLAKSGMHEPPGEYDDSEDDEDGYGRNGANFANAFEYARTNFHRFSGRHLAQIQHLSAALVYSSNIDESPYAVAFATSTAFEDLATSFTREFCSLLGLSAESPLYVAATAGTIALPRLIKFIGATRSKRTEWTTANEMAFETPLPESMTYHSIFVCPVSKEQTTAANPPMILPCGHTLAHDSLRNITKGSKFKCPYCPIEGQIKDARQIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS08</accession>
    <name>A0ABR3ZS08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NAM7</name>
        <name evidence="15" type="ORF">Sste5346_000839</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="14">
        <location>
            <begin position="97"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="12">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="12">
        <location>
            <begin position="119"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="12">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="937"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1031"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1121"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="937"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="961"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1043"/>
            <end position="1055"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1153" mass="124491" checksum="AB915C268200671E" modified="2025-10-08" version="1">MEGAFNHVGNHLISDSAAAIKAGDNDDLSSIDADENLLYSKYGGRDGLGSATRRRHDDDDNGTEAAFDDADNDSVVSALADNVQYAKLGEPEEEEKEQELPAHACAYCGIHSPASVVKCMICNKWFCSARGNAMSSHIVNHLVRARHKEVQLHPDSSLGETVLECYNCGTRNVFILGFIPAKSDTVVVLLCRQSCAANTSAKDMSWDVGRWQPLIEDRQFLSWLVAQPSDAEQLRARHLTPPMIARLEELWKDNANATVQDLERAASVDDDPHPVLLKYDDPYHYQNIFGPLVKMESDYDKKLKEAQSEDNLVIRWDFGLNNKHMASFILPKIESGDVKLAVGDEMRLKYKGELRQAWDGVGYVVKIPNNQSDEVTLELRKTGNDKSVPTECTHNFSADYVWKATSYDRMQVAMKTFAVDEMSVSGYIFHKLLGHEVAVAPMKTSMPKKFTAPALPELNGSQISAIKAVLSTPLSLIQGPPGTGKTVTSATIIYHLAKLNNSQVLVCAPSNVAVDQLCERVHRTGLKVVRLTAKSREDVESSVNFLALHEQVRMNDTNVELARLQQLKNEIGELSSIDEKKFKQLTKAAEREILSNADVVCCTCVGAGDPRLSKMKFRNVLIDESTQSAEPECMIPLVLGCKQVVLVGDHKQLGPVIMNKKAAKAGLNQSLFERLVKLGFAPIRLNVQYRMHPHLAAFPSNMFYEGSLQNGVTIPERLRSDVDFPWPVVDTPMMFWSNLGNEEISASGTSYLNRTEASNVEKIVTRFFKAGVKPADIGVITPYEGQRSYIVTTMQNTGTFKKESYKEVEVASVDAFQGREKDYIVLSCVRSNENHGIGFLSDPRRLNVALTRAKYGLVIIGNPKVLAKHDLWYHLLVHFKDHKCLVEGPLSNLQPSLHQFSRPKHSYRPPRAFGNGIGNEVSNASLGAGSMGNGGGHGGAGVGGGPGGPGGPAGAGGNRYGSHHGGHHGGHHNGGSGGVRDFDTGSIMSYIPDDVSSIHSSAIGGGGGGGGGGANLSSAYPAMFSGFSPDQWPGLPGASAMGRSGGKGRNRGGGAESVAGESVANSEYTDITAGSSVIGGKGIGQGGVSLGAGLHDTVANGRMTSYSQSDRLKDYVESSGRLASGNGYRRYDDDQQSISTAGFASQIGGSGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS32</accession>
    <name>A0ABR3ZS32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ETF1</name>
        <name evidence="11" type="ORF">Sste5346_000927</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="10">
        <location>
            <begin position="28"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="341" mass="35166" checksum="6E7CED397290BC16" modified="2025-10-08" version="1">MLSTVRRAVAGPARQQLRSASLARLLSSLAILEQRNGQLSNGSLSAVTAAKKLGGSVHAFVAGSGVKAVAEEVAKIDGLEKVVIVDSAAYEKGLPENYAPLLVENIKKGGYTHVLAGHTAFGKNIIPRVAALLDVQPISDVTAVESESTFVRPIYAGNAIATVESTDPIKILTIRGTAFPAAESAAGSGSAAVEEGVDPKAEAQTEWLSEDLAKSDRPDLSTAGKVVSGGRGLKSKEEFDKIMLPLADSIGAAVGASRAAVDSGYADNSLQVGQTGKVVAPQLYMAVGISGAIQHLAGMKDSKVIAAINKDAEAPIFQVADVGLVGDLFKEVPELTEKLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSC4</accession>
    <name>A0ABR3ZSC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="5">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_000912</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045440062" description="Protein disulfide-isomerase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="358" mass="39227" checksum="1AE1F222A07BA4CF" modified="2025-10-08" version="1">MRLTNTALLALVASPAAAWKHASEANIRKALTDNERTLVAFVEPSLEPCKRLDIEWTQAAKEATDAAVLSIDCTQDTKLCAELDVASYPAIRLFHRDSSRGVQRYRGVREAPDLLAFLRRAARPVPSTVDEKNFTTLLKDDFVVFVARYGKTSNDDETLPARFEQLASTYADRYTFAVSTDLTTSPSVTCYRSHGELVRTAAELDASTTALNAFIETCAAPLVVDLTRRNELHHMGTGKSLVHYLYSSASERRTYIKEVQKLAQTYGEYLQFTTVNLREYGDDMLKALGLQKSAAQKKGPLLAVQNPSNGDVFPFPAAGINNGDGPPAAAVVEKFLLDIIQGAVPPWMPGAGDGHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH5</accession>
    <name>A0ABR3ZSH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="969"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1000" mass="107963" checksum="C752106591E0AAAC" modified="2025-10-08" version="1">MFRQPPGSGQPPPLPPDYYEGSGRGGDLDNRNIHRSIPINSDTDRSNNDPGAAIEAIDAIDAIEVDDAPSIPSSFALLSALRQQNLRTWPRQRRRDSKSPRPAVKSQQSQPQPQSQSQSQTHQQQQPLASSSSTPLHQPTPIPPDVVLPPPFHSPLSSLLALPPVSSAFLHHRSRDTKRPKQPRQRRRMPYPLNANAQERSPSHSPPLLPSPPPSAPSVSETPRDVEQLAGEFSRQQLERTTTSGIRSTGDSISISGSGSGSGFSSGPVSRNGSRHGSRYGDAFANFSPAMAEFRLRRGGNEPVMDLEVDMDQESRNDDGDCQIRPRSPLPPFASASQFGPSSSYADSIDIETGPAVPMGLQRMRMRQVTLADASVRHLDLGLKPFPRQLSPETDASQDPQPPPVAPVTETAQPPVSAPDTAPTIQAPTPAPAPAPAPVVASTGLAALAAAESIEVGDDELAPLPMESMAMMAPYPQRNFHLHSHSYSRSYHSQAMSYSRSLPHSRPHSRQLSISSRGGAPSSHCLPLSPEALAMPHLAPLHNDVPSSGYDMQGWLSSSSTVEAAASLTTGTIDNCSQACSTDGGVAKNDTSVTPHQTTGNVTEGVLPNTDNRSDRPSTEASSTKALSLASERRQQSKQFYTAYLQPHQFPCLHDNTGTVPNPPVDMLEADMEGPNTSGIDDRIATIPEEADAMATATATPTPASGSGSGSATASHATNQDSTETTTQYMIPSQRVRLIQMAMAREAERIRSESSAYGSSANGSAVIASEDQMDVEMADPTAIEASGALSALGSSVVDGSLIGSLPPLWGPDQPSDIRKYMGPFRYRLSSEVAMRCTNLVHSKPRMRRRRQPGEDSETATTNDGGSSLRSGSHKDGGSSRHSERRSERRRERHRERAREREERDSNRDPNQSRESRERPSRASRHREQHARLITVHAESQKHAISPTQPSPPPDPLMPPVPDPALMQVEYQQPTTTTEQQPLPEWRPPVPEPIDAATEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTS8</accession>
    <name>A0ABR3ZTS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048300">
        <property type="entry name" value="TACO1_YebC-like_2nd/3rd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049083">
        <property type="entry name" value="TACO1_YebC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532:SF0">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20772">
        <property type="entry name" value="TACO1_YebC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="YebC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TACO1/YebC-like N-terminal" evidence="3">
        <location>
            <begin position="41"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="TACO1/YebC-like second and third" evidence="2">
        <location>
            <begin position="120"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="317" mass="33805" checksum="5E496D31F75FF977" modified="2025-10-08" version="1">MPPATPSMASLRAAPFSWTRYACSQCRRTFVTSPAVASGHNRWSKIKHEKGAADAKKTLLRSNFTKAITLYSQMYGADINMNPQLASVVANAKKAAVPKAIIEAAIARGQGRSADGASLETATYEIMMPPSVALIVDIETESKARAMQELGAIIKRKGGTLAPTKFFFTRQGRVVIGVAEAEGEGESASENAEPVTADDILEDAIEAGAEDVETNEDGNIVVWTAPLKTGPVVAAIEEGRFKAKGLSVLSADTVWSANETQAPLGDGTGDSGVENRKLQELITAFRAYPDVKAVYSNVAQGEASDEVWQQLAQDIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTW5</accession>
    <name>A0ABR3ZTW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="457" mass="51334" checksum="526FE6011E9983F7" modified="2025-10-08" version="1">MVTGEPMRSRPQSSYDEKSRVRSHRDDYRTHAYRDNDLARRMDAFGGLDDGDDAMDAYGSAIQKERLDRYARRHAKDDMGVHSRHRKSFMGDDDDDDDDYPARAATDILPSVPQPPPAPPTPPQQQKQAQAQAQAQAQAAQHRYQHQQLPQPHQPHQPHPAHQQHQQHHPLQPMQSMQPMQPLQPQHDQYKQYEQYDQYEQHEQQHQRPPPPPPSQYPATAYERPTAPTDFYANGLSRTRAVHTDSQVGRLASRFNTDTRSVPMHRQKIPQALPGPPMAATMPLGLAPGHGGGMGVVPMGPISPNGPMPPMPPMVSMQGAPQPPPPIMAPMPMMSMAPAPPPMMMPEMPMMPEMPMMRRHPMEDDMFMGHEPVRRGRSSEQIPFANYPQEDEYVFGSGGGARRHRRRDEAASHPQEARQSEMAGLAGLGRGMDRVPDWINFVGNDPPGIDSESVLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTX6</accession>
    <name>A0ABR3ZTX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF7">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G10800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="231"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="342" mass="38212" checksum="D63F89E0C60F78BF" modified="2025-10-08" version="1">MSTHRALSVSLRPLLARQARFSSFLFQQQNQQRPWQQALRLGSVLAHSRGITPLILRTQSPAAIVLCNFRSYSSTTSPYPQQPLFQQPPPPEPQPKKRNIILRAFFFTVRAFFYTYVGLQIGQFIVKKTMLPDGLVYQPEYATEEDRVEAERIIQYLSDHPLVEKLNNDPELVQTNPHYNIPPAFRVGNLTADTLVGPGLMAIPPLTWQDEHGHKLVMIMHVGKGLCGHPNIVHGGFVATVLDEFMARCCFKAVPHNVAMTARLNIDYRAPTPAGEFIVLTAHTVSVDRRKAVVRGKLEVLGDPSDPENETKALLAEAEGLFVSPRQARTLQMMATISGTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU30</accession>
    <name>A0ABR3ZU30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046974216" evidence="1">
        <location>
            <begin position="19"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="181" mass="19924" checksum="692442E2DF9882A0" modified="2025-10-08" version="1">MLLSALIAAVAAATQAAAFTVPHGQPDGVYQVVIHPDGTEEHLLIDTIDNASINTRNEQIEARENLAEVPNYVGCYGTAGPLSIPDTDAANNALDAQCSHFNDLEPKTSFYSKSGCVVAYFCNWDAGWRCYPGTRQDWSRRITAQCGNYIGGWAEYDDWDNIHYSYGYQDFCQGGNNFCAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZYY9</accession>
    <name>A0ABR3ZYY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit beta</fullName>
            <ecNumber evidence="13">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ATP2</name>
        <name evidence="15" type="ORF">Sste5346_000293</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="13"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="186"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1903664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="517" mass="55535" checksum="4238EC3F35B901FD" modified="2025-10-08" version="1">MFKSANFARAARVARSSLATPRTVRPNFITPSLLHGSRFASTSGVGDGKIHQVIGAVVDVKFDTEKLPAILNALETQNNGQKLVLEVAQHLGEHTVRCISMDGTEGLVRGAKATDTGSPITIPVGPATLGRIINVTGDPIDERGPIKTDKFRPIHAEAPEFVDQSTTAEVLVTGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGYSVFTGVGERTREGNDLYHEMQETSVIQLDGESKVALVFGQMNEPPGARARVALTGLTVAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLAVDMGLMQERITTTRKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRMLDPRIVGDDHYETATRVQQILQEYKSLQDIIAILGMDELSEADKLTVERARKIQRFLSQPFTVAQVFTGIEGQLVDLKDTIASFKAILSGEGDALPEGAFYMVGNFASAQAKGEKILAELEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH36</accession>
    <name>A0ABR3YH36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein alcS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000139">
        <property type="protein sequence ID" value="KAL1887172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="27902" checksum="F254F4B7E6F587BF" modified="2025-10-08" version="1">MDALREVTTNRSVVMSAEMFEKLYLSPHNKVKGELRQTYGNPTPMALIGFLLCLSPLSCTLMGWRDASNFAASIIPAYFFLGGMLMFVSGLLEWVLGNSFPSIVFCSVGCFWFTFGGILCPSFGTYGFYAAPGEAATTGLSAPGFNSSLAFFLVSFSLFAVILFICSLRTNIVFVVIFLTLIPAFACLGAAFWYMAEDLEGTTALVAKLFQAGGAILFVTCACGWYILLSIMLAIVDFPIQLPVGDLSTVIKGRSARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH96</accession>
    <name>A0ABR3YH96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-xylanase</fullName>
            <ecNumber evidence="11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">XYL5</name>
        <name evidence="15" type="ORF">Sste5346_010357</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17 18">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000136">
        <property type="protein sequence ID" value="KAL1887203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF35">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046656192" description="Beta-xylanase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="14">
        <location>
            <begin position="61"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="466"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="466"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1887203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="52297" checksum="CD48BFA09DAE3E5A" modified="2025-10-08" version="1">MGRSTHLFLLGLLASASPFVSAQSYGSLSPASPGFSVGSGSGSGSGSSSGSSGSSVAASSSQSTIDLAAIGLHTLAKANGLLFFGTATDTNLFNDTAYMQIVNDRNMFGILVPENSQKWQPTEPTQNDFQFANPDRVHSVATANQQMLRCHTLTWFQQLPTFVTTTAWTRATLTAAIQAHIANVVGHFRGACYSWDVVNEALNDNGTFRNSVFFETLGTDFLPISFLAAAQADPNARLYYNDFNIEFDNNKTAAALSIVKLVRAAGGRVDGVGFQGHMTTGQTPSRAAMSAVFRKFTALNLEVAITELDVRQTSLPPTPAQEAQQATDYVSMVGGCLDVEGCVGVVTWEYTDRYSWIPSTFPGTGAACLFDENLVPKPAYTAVASVLAAKATGVPASATIAGIGAGLTGFVASSSSSSSSVANSNNNNGQNVGSTVSSGSNTKANIPAAEFIGNFGGSPGLIPASSVSATSTTNTGSGSSSATGSSSIGNSNGGNSNTGDSNGGGSYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHI1</accession>
    <name>A0ABR3YHI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000129">
        <property type="protein sequence ID" value="KAL1887302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF25">
        <property type="entry name" value="ABC-TRANSPORTER-REGULATING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="482" mass="52940" checksum="8C792398DEA3CD0D" modified="2025-10-08" version="1" fragment="single">MADAQHQTPAITKACDLCRKKKIRCQRTPGGGCVQCMRADVADCHFTPIATRKKTRRPPGHKQIAILEERLRRTEGLLHDAVGKLGTEPSYSSDSKGSTPSSASTTVQPPLAMMEENLALLSPPPPILSWKGMMALGPFSLPSFHSLPPYHVAMELVDEAFAGFYDFYPLFDKTDFLLQFRANYAHSSSSTDPAWWACINTVLSLAYRLRAMRPVRTSGDLSKETEGSCGHIHNAIAVLSELLLLHDSFPAVQALVGMAAVLQGTPNPHSASVLVTAALRMAQGMGFHRRTCRDDTANSTLSVEQKAQRRRVFWIAFCIDKDISLRTGQPFAQDDDDMDPALPPALKGVSTIAHGIFHARIGLAVIQGQIYKKLYSVQATRQSVIERAAVADELNLLLQFWKSSGAIEMDEASLTGDLCTTGLLHKLILRFTYVNCLAMVDPHATVPQSLQDESNCVSEAREALPLIQNVPQGDFFVIWQVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHY2</accession>
    <name>A0ABR3YHY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">37S ribosomal protein rsm22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028241">
        <property type="entry name" value="RAVE2/Rogdi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618">
        <property type="entry name" value="LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618:SF1">
        <property type="entry name" value="PROTEIN ROGDI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10259">
        <property type="entry name" value="Rogdi_lz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="44521" checksum="D86AF4FC512849E3" modified="2025-10-08" version="1">MSDWVIVCPLPLPTSAVRPSPSPAFDVGFLKEAPRPRQMVRSLDDHNPFKRLVDQEKIKTRLRREPPKAKVPAQKTVATTPNPPLIDTQSNELAWLLREMGDDLRGLKLSLQDCYQLLKPANQGNTLVVSTPRTEAVKGHITRLGTHITKGTIHLKMRTLPAQTLSINPNHPITITPLDDLSVLLTRSIELLDLTLAHAYPEEEPQTQKGKGKGHSAPMETFLAAQLRVLAQALQDASAILRGPPLTASDPAWSSRSAALAHFLPHLPPGISFYIGLQDSQLVLWLRALEPADVPVNLGMKFALALGTARRIEHDEADQVFSYCCEDGCAKGLHSPPPAGGSDSGRDSGEGTGTATPEGPARIYVREKIRVESADPSLLSLSAKLNALSHALVHIRRNLAAVMDDDIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIJ6</accession>
    <name>A0ABR3YIJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Viral a-type inclusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009952</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="763"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="915"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="412"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="790"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="917"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="949"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="979" mass="105160" checksum="73D9918F2B31E951" modified="2025-10-08" version="1">MDRDNPFGSSYLREGASRVQKPRLTYRQTDTTVPVNSNTGNGHINHPTGPVVTKRPSPHLRLQRRLSVTSDSSTKPAIADDESDSDVGFLPPAHSRNERRRNSASMSARSNGSTATHRNFSSNRGRVVRPADHARPTVHFSAGRSEVLLTLPAPAPAPNSSFVPSQTHNNMGGGRVPELPIAPTSTVLSRRPSNRSSAPVSAPVPVFGTNDHYARQPMYDSVYGSTAGSISTNQHGTGNSSKKTVTFDSSETEDSMSCLSNSTQATSVDDRDHYGYYDYLPEDKTKMTKTTKTAPAVQTRVTVDYSQRAPSPIMSSSSTTTTTMTPPTRSQPTRRRSQSFSGIADHEMSRTRTESDLVHVPARRSLRDSYSHIPAGAIEDTPAPASISTSSSTSSHDNGSDKNTQAQFEAHKVALEAQFEQRQQALEAERKKLAVELEETVAALGEAQAERNDLRREAAEHRQRAKSLAEEIDDLHESMDKSLQLKNVESLEMKELRADLESNKMALDETRAALIVANQTLADANTTLAQVRDSLRDEEATSALFREGKAAFEERCSDLEAKCKDLEGQVVAARDANKELHLLMAGQIEDLTATKDALQVRIGVLEEEEATRVAATAASVAAAASAEEKAATDAKTFAEEKASLEEKLAATEAKCTTLEGDQEAVNTEVKDLKDQIETLTAEVTSKTTELESLTAELEKAKEENTAHQETITGHEAAVDKARHDAQEAATAAATEAVDDLKETITKLEEAQAALTAECESLKTKAAANGDKSGEGEGGDSGEAAAPDAELQEKHLKLEASHNELQEKLTALESTLATEKTEKEAAAAALAAAQAAQTEAATALASAQEAATAAKSAKEEAAARAAQVPELTQQNANLATELAAHNDRVQELRAAYATSEAEGMALRDQLAKMRAKLAGVAGSVTSNGSSSSKKGSKKNEKDPLVIVRTPGDRGRFQVMRKSDLHRSPSRSSRKTDYDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIR6</accession>
    <name>A0ABR3YIR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="18746" checksum="FF3F08723F21A791" modified="2025-10-08" version="1">MLSIATLFDDEQRLLNRVWIVLLGLEALLVLFGTISAVVRGVVAIRRRRPGGLRRADSNHHHHHGRPRRVTIELPATGFEIYDDGRYDGQYSNRPVHVYPYSDVDHYDDKDYYDGHNGQMMTAEPGMYAEHDIFYTDEKFWPHTPTRAQTPTRILNSPSQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIV8</accession>
    <name>A0ABR3YIV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010269</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000125">
        <property type="protein sequence ID" value="KAL1887359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050375">
        <property type="entry name" value="MFS_TsgA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702">
        <property type="entry name" value="L-FUCOSE-PROTON SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702:SF13">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="642"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="677"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="718"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="763"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="892"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="918"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="954"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="982"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="5">
        <location>
            <begin position="33"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="353"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1017"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1050"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1077"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1131" mass="121631" checksum="5C34944608CB7240" modified="2025-10-08" version="1">MDATASKTFPDRGPAVLAVTTATLVLCSVFVLARMVCRLGIVRRVGWDDYFIILAWLLAFGLSLTINLGTRTGLGRYDANIPPEGRARLRIREYVFSILYNPALMATKTSILIFYLRLSKNTVWILRLGSYIVLIIVNVAGIVLTFINIFQCRPVAAAFKDVPGQCIPLLTEFICSAPVNIVTDLAILALPIPVLTGMRLPTRQKTILVLTFALGIFVAIVDVVRIYYLQQAINIVRPGSSSDPNSIFGDGTDFAWNASFSFMWSAVEVNVGITCACIPTLKPLIIKIFPALVIDPYASDYGSSYARGLDTSNASSRLGAAQPARPAMAPAPAAGGAAATNNEVARIATREGSGTPLILGGPESVSQGQGSSLDSGSPRPPDLATNQISAADHAQDARPAKPAAGENLDNAASPDAQASPRSPLARATFGARHAVSAVTHHLHHTHPHKSKSSSDDKDQSVYFGFVKLNTPKNMLEATASESWRYCTIVAILFFLWGFSYGLLNTLNNVVAAVANMTTTQTVGLTSAYFGGGYFFGPLVVGEWVLRHDEHHRRRASESQRRDSQPREKRRKRATGLATIPATAATVASHATSTIAKHSRFSESSDNQIGGFKATFMVGLCFYGIGTIMFWPSAVLTSFPGFLISSFVVGFGLSILETAANPFLVLCGPMEYAEMRLLLAQGTQGVGSVLSGLLAQNVFFVNVGTTGSTNSTTLLDVQWTYLAITLFCVVLILFFYYMPLPELHDAELELAASRMPVHGTKRSVFGLQLRTICLILAVFAQWTYVASQESMSIYFHDLITSWLPGGATTTSSLVNMNSGGKSNQTLTSTVVFFMATSSINPSADSDNPAGLSMSVPNYLSIARTAFSVSRFFAGFIVYLGVKHPKNRWLPTPRTILTISTVLMTVFALLIVVLHPSSNANLIMVPVTLFFLAEGPMWPLIFAIGLRGQGTRTKRAAAYITMGASGPLFWPFVMYAIMDRGGTIQIAFIIVVALMAACTIYPLYLTFVRDARELTKVAPYDSRPRSGQAPSGGRHPARGFVGELDMSILGNGPDGNGSGSGSGQGSSASKAQPNPEPRTQQAQQEEVTAEKSSSVPEEPEVVAGPSTEPSLVSKENELRQQSSSHQKTAPKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJA8</accession>
    <name>A0ABR3YJA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="64"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="170" mass="18967" checksum="7AC53B3B78FFE171" modified="2025-10-08" version="1">MEPLTKVDSAVQGLSSSPPKEKGHRKTGSTSYPGVRNIVDLEAEGIELKLAPETQKTGWKINTSPNSIDEKDILKKLLTEPPVKKIDLHFPLGLEVTARNMKGVTIKDAMDAIHKAFKKRVDDELELPYLKGFEWDKEESWTRLIVHLQRESSAPHSSGGGGKKKKNKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJP6</accession>
    <name>A0ABR3YJP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF39">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05010)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="514"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="103"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="613"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="679" mass="74353" checksum="D2544D6818A99D96" modified="2025-10-08" version="1">MYLAYKYIKRKRQEKRDRLEEEEEERQRQAAGASGLAGDINGVPVNRDGVVAGHGRGESLEPLQPGAIPSTTVAEKKAKAKKAEPTPEEKAEKKRRYIYRCKVIFGLMMPFTLQGLDTTIVASALPFIASDFNQIAQLNWIISAFNLTSAAFLPFWSQTADIFGRHATIHATLVVMLIGSAICTGAPTNAFGVLLLGRALQGVGASGINICVRTILADRVSLKEYALHWTLFALISAFSFSVGPVIGGYLTEANWRWCFAINLPVAVVAIIMVIVLLRNDLLGPQPLPELQRHDVSTHHGRFLARISTLDFGGQFLFLWGLGLIILALTWGGSAFGWNTAHVLAPLVIGFALTVAWVIYEYLMSPGRAMSRVFPTQRPMMPWELLSKRDIGLLFWINFSVGSAMFANLYFMDLYFALVEGNSSSKAGISLLYFLPGLAVGAYSAMFASNIWPRQTIHPLLLGGITSAVGVTVLAYAVHAQYTNLVYGMMALSGHGVGIRMNPGSLHGLAFFPKETAAISCIVSFALPFGGTVTLTLMSTVFNNKGGSSTDIATVRNAIMWAFIAIIPFMWVSVGLTTLLGNVWILKDDSHEVVNTPYLWSLLFRKPIVREKRTREADDHFSKQTRAGVTTNDEENVLAEATLPGQPETAGHELSEVAPKEDQNQNQHQPQYINGAQSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKF2</accession>
    <name>A0ABR3YKF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">D-arabinono-1,4-lactone oxidase</fullName>
            <shortName evidence="9">ALO</shortName>
            <ecNumber evidence="4 9">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ALO1</name>
        <name evidence="11" type="ORF">Sste5346_009638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23756"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16292"/>
            <dbReference type="ChEBI" id="CHEBI:58277"/>
            <dbReference type="EC" id="1.1.3.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="4 9"/>
    <dbReference type="EMBL" id="JAWCUI010000095">
        <property type="protein sequence ID" value="KAL1888313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030654">
        <property type="entry name" value="Sugar_lactone_oxidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01678">
        <property type="entry name" value="FAD_lactone_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="10">
        <location>
            <begin position="38"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="558" mass="62474" checksum="375F745806A86E94" modified="2025-10-08" version="1">MSDFDPSAYDGVDLAVAGAKQPFAARRGYVHATWARTFASRPELFVQPSTVEEVEQVIKLARHRRRRIATTGCGHSPSDMTCTSSWLVNLDRLNRIIDIDRESCVVIVEAGIRLYDLSAELAKHDLALPNLGSINEQSLAGACATGTHGSSLRHGLLSDDIVALKITLGDGTTRTCSRDTTDPEESDLFRAALLSLGTLGIVVEISLRTVPSFRLRWSQTVDKDSVAFEAWKRGDTDCTSRHSELWTQSHFVRVWWFPYTRRAVVWKAEDCVETPEEAPDFTPPTSYYDSTLGYLVYHNLLYLSRFVPRILPWIEWFVFGMQYGFQNGSTTSGLQPSDKALLMNCLYSQFVNEWAIPLARGPEALTRLGAWINRLKPGDEGYVDHRIPFSADGLYIHAPVEVRVADTAAKQDLRVKANPNSLSTRPFLDPTPSDGPTLYLNAIMYRPYFKDPPGVDRYYEAFEWLMRDLGGKPHWAKNFGSDHSELAAAYGTDLTKFNAVRNAADPDGVFVGPWHRRYLLGEGADAQPDLRLEEHEKRRALATDYTVFVSGAVGEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKX7</accession>
    <name>A0ABR3YKX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF4">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="882"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="649"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="851"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="859"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="912" mass="98865" checksum="6F0AA4FEBF8DECD6" modified="2025-10-08" version="1">MATPYSNGYTPSSSSSSAAAATRNRNLNFNPSSPFVSSSSSSNDDFVALTLNVLRLLWGYSIRKLLAAAASVGSVLLTGTRASTLLKDSRRRRPRPQPLAIVAAETLLRLVRHNLAPQRIFSVPHFLVVFWVLVLLWGERGNFHAKVMHCHWDHWEKWPAGAEPHHLVFVADPQIIDAHTYPGRPWPLSSLTVMLTDNYMRRSYRELQEQLRPDTVFFLGDLFDGGREWRPAHGTFQDPSWSSRPDREQGYAKTWRKKYDENYWLKEYARFGDIFLDPWTLGGTDPGPGQRGRRVITSLPGNHDLGFGSEVQLSVRDRFQSYFGEGNRVDVIGNHTFVSVDTVSLSADTSDRAGQSDVQKIYQPTEEFLKNVAWDKTRAVARELRFQRGAGEEVSYPHRVEDLNAAKFDTAALAKAQGAGDALQADLPTVLLTHVPLYRPPGTPCGPMREHWPPAKPSADEPNTPVFPDHRNAISVSRGYQYQNVLSESDSVKLIKSIGNVKHAFSGDDHDYCEVVHDDVQEKVKEITVKSFSMAMGVPTPGFLMLSLYNPIDAKGNPLATVGAPPGEIPPPTMQTHLCLLPNQLSTFARYGGMAVVSIVLLAIYAVLIQVLNLPVFAFDPLGLDSTSPSSNMPSSVLPMFNKAKVEDDEYGRGNGGGAGSYGADAVSTNSEKGGGGTSDSSGFVSFRPAPATYSRGRSYSNQYPPQSQSQHLGHGRGQKGRRNGQAAKTSSPANAYEMRGPKIQIARDTDDDSSDDSAYGGNDLLSDDYMVDVNLGGGGGGIGGGSSRWQPAARRGVFGVSMAAISGVRRFIMGTLGLRGGGAFGGRRRRGGGGGGGGLSGLLGLGGGSSGGLGRSGSGASSSSAAAARRRRSGRSSQRRLLQLAGWEFYAMAFRVAWMVVAYWAYLNHKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLA0</accession>
    <name>A0ABR3YLA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="313" mass="35319" checksum="E78515FD94715D71" modified="2025-10-08" version="1">MPRKNMTLRDALLRLKPFIPCTATDTKNSKYPPWPNVTARHWTEFNIQTLDDSYDNILDTELPSDVVDTLTPPVVLDGITKWAKLHLGLQEGCALYHQFTHADQTVVAKLPHTSTKLNIDHSILLQNVQRIQRDALVVDLGRTSTKWTSLPIVRKHTDIANETMWPLRQVANLCRIAGTRYRYIQTNVELVSDWKVAVQSVPWNTEVSSGSGRNILTTELALCDGHRELVPEKDLVPIDAWDTLVSNDERGKIRRHQYSQRELLANTPTPSSYETPEYGNAAAVAGIGGIDYPERGVDILNYNFGVSFLSHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLG3</accession>
    <name>A0ABR3YLG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000097">
        <property type="protein sequence ID" value="KAL1888229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase" evidence="2">
        <location>
            <begin position="223"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="306" mass="33349" checksum="403554A155BE8065" modified="2025-10-08" version="1">MPLSSAIADPLEDAFYRLAAFAHTRPTLFTTASVSAVSLCFIVPAAVRSYRGYLALGPGGIPYNVWGWLYQGLGQPFAVRDPRSTTDFEKPKSEVLARYGGSARAQKSYLDIDTTLPAREGSRPTVPGYTAPQRQTTDVASDPAKTRATQEEFLKAVAAANPTVLEIRPSQLEGTSTPALWAKDAVILGAKMFDRKPTDLPAKGSKKDKKSSTKAKPVRAPVEICHAHPEASSHMQFSFGDAYWVVKAGWGERHLLAGSLAAGVPPTYLIVYAPRNEKELKVWKELVMAAVRFSVDEDVDINDVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLZ0</accession>
    <name>A0ABR3YLZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ACP2</name>
        <name evidence="15" type="ORF">Sste5346_009602</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 13" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="14">
        <location>
            <begin position="62"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1888394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="141" mass="14994" checksum="BD7C34FF4679891F" modified="2025-10-08" version="1">MFRASVARAAAVAAPRAAVAVGRVAIRRAVPAIAPLRLASPMKAIAVTPVRFYSAAAGLNKDEVEGRIISLLQGFDKVNDASNIKATSHFANDLGLDSLDTVEVVMAIEEEFSIEIPDKDADSLHSVDKAVEYILNQPDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA3</accession>
    <name>A0ABR3YMA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="694" mass="75328" checksum="8F833655ADA2FB72" modified="2025-10-08" version="1">MASKHEVFDSDDDGDDLSPLSSPLASPKLSPLPLPPIETETETTTTKSTNLAHATSTSTDPSFFRDVYEEQQRAIGVQLAPFPPGFDDSHHDILAERSAVERSSRDPWEVPSSPIEVAGQQLRSYLKRKREEGQANRQNAAVVVQLEDLCNDNAPAQAKKQRTDANIGGVAALETISIPLEPFTPSRLHQYPRMLSSSINEEPLPRQSISLDESLEAAPPFQQPPYEEILPPNEDVTQSTIAFTTPSVYASSGRRALGSSNNNSNSAQKQLKISSNNMDIVKEEEVVMVAQDSTPTRRTRNAADMAQILSSPDIIAEPTSRESPRHQSPLPEEDEDPEEDEEGGVEWGSHRSREEMSTAEATRPQSAQWRSSIVDELSTSIDVPVQSEAVQEVYEPDASCDLLKEKRPSKPKKKSPKKQKKKAVFIAASDDEDEDIIVSAAPPVQSESDFSDVPVKSKPTAAKGKRGPKKKTAQEVLSVELSSETTLPTKAKRGRGRPKRQKTPPQVIDSDDEEVVLVQGAVEDDIEIKIEPSETKTDEYTAAPDSDADSEAEPDLPTPDKTKGKKGNKASAKDTEAGRGRKSTKVDAANAVPSQEAVEEKTVFSNTSGNASAASSFKVVAEDKQVAQKTAVVAKKEKPAPILEDSKPALSTTGPGRALLNTGLVATASQGKIPYRVGLSKKFRIAPLLKMIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA7</accession>
    <name>A0ABR3YMA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008869</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF123">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="395" mass="43594" checksum="127A2A0DB0321EB7" modified="2025-10-08" version="1">MTVDYPTRSSTVVVANAALLVITGIFILVRLWVRVFLLHQVGLDDVLIWASSVFGFTLSISEILMTKHGLGLHIDDVSDADFESFLVLQFVAALTYIWAFVLIKLSFAVFYLRVIPTSGFRRLNYIIIAILAAQGVEETFVVCFACRPIYKFWRPAVEGTCLNLLNFYYISFGIKLATDIVLFLEPIPTLLRLKLPWVKRIGLVLMFSLGLLTCVISIIRATYLNDTSNDVTWRLVDPIDWSTAEVCSLIICACIPYVRNLLAEIPFVNEALGLSSNHSKGYPSNYGARSGQDNSIALQTQRTYIQSRNLKGGHGTASNTATVTANPYGNGNGRDGNGNGNGNGRIRATESTEEIFPNYMDKQGGIVVSTDVKVAVEESSEPGRSQARSSYSDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMJ9</accession>
    <name>A0ABR3YMJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Centromeric DNA-binding histone H3-like protein cse4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CSE4</name>
        <name evidence="7" type="ORF">Sste5346_008931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810:SF1">
        <property type="entry name" value="HISTONE H3-LIKE CENTROMERIC PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="6">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="149" mass="16657" checksum="91AF1853F2DBC2F7" modified="2025-10-08" version="1">MAPKRAAAAPAAGKRPGRPSTGGVKKPARASNVQPGDPVPQRKQRRYRPGTLALREIRKYQSSTDLLLLKLPFARVVREIALSVRPVDEGMRWQSQAILALQEAAEAFLVHLFEDTNLCAIHARRVTIMRRDIWLARRIRGLWGAGGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMQ8</accession>
    <name>A0ABR3YMQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IME2</name>
        <name evidence="7" type="ORF">Sste5346_009040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07830">
        <property type="entry name" value="STKc_MAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="882" mass="95755" checksum="B9036E9B57705156" modified="2025-10-08" version="1">MAVTHDLTHRGSSSHHQAANTMALEERFEVLKEIGDGSFGSVVLARVRGAGSNVARRGTVIAIKTMKKTFQSFTPCLELREVVFLRTLPPHQHLVPALDIFLDPFSKKLHICMEYMEGNLYQLMKARDHKCLDNASVKSILFQIMQGLEHIHAHNFFHRDIKPENILVSSSGHQETSNSFRRYSSLVTPPSTPPSYTVKIADFGLARETHSKLPYTTYVSTRWYRAPEVLLRAGEYSAPVDIWAVGAMAVEVATLKPLFPGVNEVDQLWRVCEIMGSPGNWYNKAGQRVGGGEWREGSRLAGKLGFSFPKMAPHAMDTILQSPQWPASLSHFVTWCLMWDPKTRPTSTQALAHEYFVDAVDPLRPKSSASRILGRKQSDLGRASKDSGSSTPTSTKQPWYRKSLIGRSESTAEVNAVSKDPALSTMVTSPTAPSIALPPAAPVHAPAPAPAPVPSHAQVPARVPVPSQGPVAPAVAQAPSPAPAGPRPAPEQHLSAEAVLPKVRPPASKRTTWTNGPSNVAPMPILPTIRPISPMSDAVTAQANNRTPMYNDAYANAAGRADDKTPKKIGRQLSVASSTNHYADLHRQQAEQALNGNTGLVSPPSAHKESFFSHLRKRARRFSGRHQTPISPAYDEVEAQAGCGPWASNRSSMVIDQQAQASYMPMAVPVQNTSALPSSNTYDSLDKQSYAGETNSGYLPTIPAHSSTSNLTSSATMGNTVGVPLAGTTNLKRHHSLPHHHPRSVDNLLVAARSGGGPISSRTRRAQATQGVYQYDAPDEEDELLDEVLNSTHRAMKRLEKDGKPTLRQSVSNIAISNPYPTPSPSASGHNVLFGDGNEAVTPKPLDLNKKAADYKWPTPPYDENDWAASASASIWAASNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMR6</accession>
    <name>A0ABR3YMR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Clr6 histone deacetylase associated PHD protein-2 Cph2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CPH2</name>
        <name evidence="4" type="ORF">Sste5346_009102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11399">
        <property type="entry name" value="bHLHzip_scHMS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019006">
        <property type="entry name" value="Sre1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09427">
        <property type="entry name" value="DUF2014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="382"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1196" mass="128878" checksum="D595A4571322064B" modified="2025-10-08" version="1">MADQQEADPAFAGLESYDVSSVGTPTASANDTSSLGLFDLQQQQLQQQQQQQQLNSTTDIKTEANYSSRASNSGSSSAGSNSNSKSKSTSHRKKKTKKNSITSNGSDHSNNSLGGSSNNSVNLNDSPITSAPPNLTTSASIGPDSIPSNAATPSATSGVFFPQDPNNNNWGFYPNIPNAAGFDPSVLQSGFNPAAIPSGFYNPQFNFAAQQWGAPNIAPQFTGQLPQRPRVDSPQQGQQQPSDQGQDGDILLQQQQQQQQELLLRLQQQNFFLQQQQQLQLQQQAGSFSQQGPGQVRPQLAPEVLSSLTLAQQDALKNIAMPAHLQYHSPKSEPSPQSSAGGGIPSSPDGADPTRSNSRKRKSSADDDDDDDDEDDDGTQPVKKTAHNMIEKRYRTNLNDKIAALRDSVPSLRIMSKSARGEDTTEDREELHGLTPAHKLNKATVLSKATEYIRHLEKRNNRLLDENGQMQQRISAFEKLFMHGALSNANSMSPMAQPSPIAMQFGGGGQQDPMASFMGATPLATPRADPAGMIPVPEDMKRILQAQAAAGRPYPVPQQPFQATPAVIRQQQIQQQQQQMQQNRWQTAGPYLGKMMVGSLAGLMLLEAAREQEIDPESTQGRGLFALPLQLLRPLVASDAHVGFGGYYFSTAQIVSNLKFMVLLGMLLWAFVPSFFSAPATTKQEKSQQIRSSPQAAPSLASPIHIRRNAWLTAIQTVWVPRHNFFLEAAALILKMMKLSIRNMFGIQGYQMLTGLTQEQETARVKAWIIALDAQLAGGDIEINESRLTLTLLASHTLPDTPLRLMLNALHIRVLVRHLGKNALFDAIAAHWARGKWNAAREQNTLAMQLQRDGSSGKAVSGPSLQADDELPSHLATLLAEGCDDVLNDDVIQRAYNLAFNRPTTFAVPAGAVDMDGMNAVVEDPAVRSPLDAVAAWFSSLLVHRILTTSLAAETDEAQSDLASSISTELDLASKIAPIGSHAQVRALVARAVLIDEKRGASIAVALQALRPSLNPDKHPHYSHGLPPLIDAPLTPLVPDREALMALRCAMAIAHLQRFAVPPQDILASVDAVLPGAQNEVSLLACAAAFRLMLSLHSHKVAAETCAVSLEQLAGSLRVWIGGPAGDHGGLDAGVRHSMVRRCLAVTRSVVGMDHDTGYGSMSEGEGEGVHEYDDEDTIGEASVDTIDVAPEGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNY0</accession>
    <name>A0ABR3YNY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OGG1</name>
        <name evidence="12" type="ORF">Sste5346_008804</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="11">
        <location>
            <begin position="143"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="429" mass="48110" checksum="B1AC4D7A3108B532" modified="2025-10-08" version="1">MGRLAAQWQKLPVTLTELCIDTTLRCGQSFRWRKFDDEWRCTLHGRILSLKQDAESLYYKAAFPDEAAIAASSGTPRPRSDDAPGGDDTEALLRRYFRLQLDLRALYDQWSRDDANFRKKAPQFSGIRILNQDAWEALVCFICSSNNNISRISQMAHKLCIHYGPRLGTVDGEDYHDFPSPAALAKPSVETHLRQLGFGYRAKYIVQTAQKMLDEKPAGWLNQLRNPACPPPWGEELPPPAKTGPAVSNNDDCVPSYKTAHEQLLTLSGVGPKVADCVALMGLGWGEAVPVDTHVWQIAVRDYKFKKIASKTFSKAIHDAVGDHFRNLWGPYAGWAQSVLFTANLKSFSEQLKGGEGEDKDKTVSTKSSPKSPSKAVKKEILEEEEEKVSAKVTTTKRRRTTVVKTEEDVKVTVVEEVQTRSSKRRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP56</accession>
    <name>A0ABR3YP56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF12">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_6G13830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="28431" checksum="6747677D8BCCBDB7" modified="2025-10-08" version="1">MPLYQPPDVHRPVLSQFSLKGKVALVTGGSRGIGLQVVTGLAEAGADVAFVYKQSTDTAATCERLQKLTGQKIVAYQSDVTDRKRIAETINQVAADFGHLDVVVANAGVCQNVPSLEYDEEKWAFINSVNYDGVLWTAVAAGKIFKQQGRGNLIVTASVSATLVNVPQTQAAYNASKAGVLQLARGLAVEWTEFARVNCVSPGYVLTEILTKQPAELMNTWLGQIPGRRVCDPAELKALYVFLASDACCYMTGSNLVIDGGYTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPM2</accession>
    <name>A0ABR3YPM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Caib baif family enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025496">
        <property type="entry name" value="DUF4387"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14330">
        <property type="entry name" value="DUF4387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="2">
        <location>
            <begin position="183"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4387" evidence="3">
        <location>
            <begin position="584"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="687" mass="72703" checksum="6C3FDEA9FD5C81E7" modified="2025-10-08" version="1">MGSVPSSTPSSDVLCQIVTPVGMLGYGFEIDEVYRGLELARRDHPDAPTALILDSGSTDSGPSKLALGSMTCPESSYRRDLLSCLRIARQYGVPLLLSSAGGDGEDAHVKLFGKIVADVADRLNKEDDFGTETSLKVLSVFSTLDKDLVKNRLTAGNITGCGPCVPTLTAEALDATTVVVGQMGPEPFIQAMAAHPDFDIVLGGRAYDPSPYVAYCAYHHLGKTAATADVLSIDPLILGGFTHMGKIMECGGTCATPKSRGSMATVYKDGSFDIRPLAVGAVCLPLTTAAHTLYEKTRPDKLAGPGGDLNLTTAVYNQLDDGVSVHVKGATFTPSWNREGGAYTVKLEGARVTGYRSIFMGSFCDPILLSQLPSLLGQIKKYVGQQHTHLDASTWDLDFHVYDGKDHDGEDAGMPAIIPQGPPPGVVFIVGEALAPTQAEATSLASAARIGCVHGPYKGQKANSGNFGMGIGGQGEIEMGACAEFSVYHLMDLVKGEEGAKEVGTEGTSLFRWEMAWTGPKDGKRVVDLPFRPNSDRAALVNTTAKELKTNGQVNGHTNGTTSTEPTSTSAPSTSKSTTTTVGALAKMLRSKNSGPYEITLDVLFDDPAVYAKVKESGVLTPEKVAALYGLKVDQLVYCGFFDPALAFKATLPRMRHGKPVASGGYMENDVHGSQKYKPLMNVAIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPN5</accession>
    <name>A0ABR3YPN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBM21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="388"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="748"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="786"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="830"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="884" mass="94475" checksum="F9D3A8556F61E6F4" modified="2025-10-08" version="1">MPYTPPSHRSPASSAASSPDTSRRPSFNAASKPVNVSLSFSPAPPPALPRSSSYLTRHRRTPSAVSNASTNSSTISGQPTPQATSEDLKGMVPVVVPGHGYDEHSSVRQSPPPITGDRRGMPTGAIISPPDSPPTSDDEDRPKTRGRRLENTTELKQLHEAISQLPQQRRASSPNDEPADLGVLVVQPIPPVPVVSSISGINGASMSRSNSTESNGMRHSFSTSSLEHLRIGGGRSSSIGSNGRRVSHMRSATEPSVSVSPSAGSSIANSDEENDLEILAKPPMVRKKSGELVRPALRLGSGRRPSSMPGTPTFSKVVHFDSHLEHVRHFLQVDRPLAVSAGSSPVEVYDSETEYPFNSNVPGAIKKQQRGGPPFEWEIVFTKFPVETAERKALPVRLERVWLSPDQKSLHGSIACLNLAFSKSVVCRFTLDYWKTTSEIAAEYSAEIVPRIAPQGHDRFNFTIKLSDLANLESKTMYFCIRYTVDGKEFWDNNNGSNFQLDFKKKMLPINGKGGLQNGALPRSHHRRTNSSGSPRPVSMPVSLDDFDGDANGSKMFDQSVHEYLGESEHPALRLKSSQSATSLASDNLTTRLASPSGQAFANRYDFGASLSAAMQAAKDAMTTKTTTNKRDGGLYMKSGRKFTIVPAPSAAAAVNVAAASANTNQRVIAINTTQEPTTVALPVAALDRDSRTILTESALYGPGGIASKSYDEIVSKYCFYVPKPSLSTKDGSTQNGQTDSADKNANAASTASPASTITSDGSPVQTGRFYHQPARPRWHGDLPSSRDLSSSSIQSFGSAATALPLTSQPRRGTLYPAGSPPTLEDKTDSASTSSNNTASPASPASLVGAFPPFAGTPPPDFSYMKDRFPFTNTDGHSTPAIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK2</accession>
    <name>A0ABR3YQK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477:SF1">
        <property type="entry name" value="BETA-FLANKING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="110"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="278" mass="27634" checksum="F32E29957AE567FA" modified="2025-10-08" version="1">MWGGDDNNNERQQYGGGGQGGHHGGHQGNYGGQQQGGYGGNGGGNQEYGRQDQYGGQQQGGNYGGNGGSNYGGPQGGNYGGQQQSNYGGPQQGGGNYGGNGGYRHDDDDDLKGAAHAAAQHSGDGESANFFGDILNKIGGNKSSIANEDLDEGDAVQNHQQYYGNGNSGGGQATAGGMGSAAAMQALKMFTSGGSGSSSGSSGASSQSQFIGMAMSQASKLFDSQSSQGNVESGASKESAVQKAGEMALKMYMKSQGGSSGSSSGGMGSLLGLASKFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQM5</accession>
    <name>A0ABR3YQM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ADH1</name>
        <name evidence="10" type="ORF">Sste5346_008142</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="16"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="37236" checksum="19DC0634BEC865A9" modified="2025-10-08" version="1">MSIPTEQWAQVVEETGKMPTYKKIPVGKPGPNEVLINIKYSGVCHTDLHAVLGDWPLPTKLPLVGGHEGAGVVVARGELVKDVAIGDHVGVKWINGSCLSCSFCRQMDEPLCEKATLSGYTVDGSFQQYALANADHVARIPKDLDLEAISPVLCAGITVYKGLKESGARPGQHVAIVGAGGGLGNMAIQYAKAMGLHVIAIDGGDDKRDNTLALGAKTFVDFTKSKDIVAEVKAATPDGHGPQAVILLAVTEKPFQQATQYVRPHGTVICIGLPANAYIKAAVFETVIRMVTIKGSYVGNRQDTAEAIDFFARGLIKAPYKTVGLSELSKVYELMHAGKVVGRYVVDTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR09</accession>
    <name>A0ABR3YR09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylglycinamide formyltransferase 1</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">GAR transformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ade5</name>
        <name evidence="10" type="ORF">Sste5346_008190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369:SF2">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="24719" checksum="2065D3F713CC05DD" modified="2025-10-08" version="1">MADTCRILVMASGNGSNFQALVDGIAAGSITNARITRLIVNRGKAFATQRAEKAGIPWEYFNLVTHGFQAKGEKDQAALQAGREQYDAALAQKILSGPSEDRPQLIVLAGWMHVFTKAFLDPLDAAGIKVINLHPALPGKYDGAGAIQRAYDDFQAGTLENNTTGIMVHFVIDVVDRGAPILTREIVVQKGETLADLETRIHAEEHALIVTATQKVVQDVLATEKGSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRD9</accession>
    <name>A0ABR3YRD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="151" mass="17522" checksum="B2F6869CCEB5442A" modified="2025-10-08" version="1">MDSTNTTAGLPPSIEAGLLLIAEALQGKKRTRPRADDHNDVVSQSIEFCIMILLLFYLMKNCIDKKNEDKGKDKDKTKNDKDNKNSSSSSNNSKDITLRLHVYIKTECSCSRRYTNYDEQRRTEQRWGEQRWDQQPYDGRLWGEQPPSQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRR7</accession>
    <name>A0ABR3YRR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="211"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="263" mass="28059" checksum="70B3DDAC36FB6A2D" modified="2025-10-08" version="1">MADNVSPAHSHTHSQSSHSGTTMTESVASTAASTATSTAASATSTQTPGRPPKRIRLNLACNNCRRRKVKCDTEQPKCRNCWLRDEECLTTDPRYPPSASPDGRGRAEVRRWATPNGLMPGQNPAATHRNQAYVAKHAPSGASSAAEPSSAPPEHCQQHNQTQPAPSPPTPRRPSTIVVAENNTPSASGTTATTTEAPISWVTRSYHYSETAEQAREDEDGGNMDTENGPAGPTTVATTSSYDADVVVNTDDATPHRVKYMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS23</accession>
    <name>A0ABR3YS23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxiredoxin type-2</fullName>
            <ecNumber evidence="8">1.11.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AHP1</name>
        <name evidence="8" type="ORF">Sste5346_008069</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="166" mass="17669" checksum="FAE559740FA705C1" modified="2025-10-08" version="1">MSGLKVGDAFPEGVVFQYVPPTGELDIKACGIAVPYKASEEFKNKKAVIVSVPGAFTPTCQEQHIVSYLQNREALKAKGVDQVIVLASNDHWVMAAWGKANGVADDSILFVTDVDAEFSKSIGWANGPRTGRYAIIVDNGKVVYAEADTVPKSIANSGAEAVLARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS75</accession>
    <name>A0ABR3YS75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011802" evidence="1">
        <location>
            <begin position="17"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="67" mass="7138" checksum="53EF59B8FB968D76" modified="2025-10-08" version="1">MKYSLCIAALISVALAVSHEEHQAFIRRQSNVQNTVSANTPAMTDQDGNVVPFDASKVYMAGQAAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSV0</accession>
    <name>A0ABR3YSV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007677</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="224"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="60067" checksum="62E3CBD34C2C6B41" modified="2025-10-08" version="1">MQDLATLRAGGYRDAGLTKLKITEPLKSFPPEIFDAGLASTLQILDLSGTGLSALPADLGARLPHLRIAFFSGCNFTKFPSALAGCPKLEMVAFRKNGMEGFEGSEGESFDGVAFPPQLRWLILTDNKLAHIPASIGNCARLEKCMLAGNQLTGLPDSMANCKNLTLLRLAANRLTLLPPWLLTMPKLAFLSFAGNPCSSPAKISTDTRPSTTPSLPYVDWNQIEIHHVLGEGASGIISKGTIRSSNSGNISGNSSRGPSSTLNSRGPSGFNTPSLSGTSTPALSVSGASVFSNVSSLSALSAVSSTSNSISTPSSLSLSPSTPVAVKIFRGALTSDGTPYDEMAACLAAGQHVNLVQVHGQIRWNDDEAEAEAEAEAEKEAEKEAAPAFRGGLIMELIPPQYRVLGNPPSFDSCTRDSFDSDASAAGLPIPAALKILSGVASAAAHLHARGIAHGDLYAHNILVARGDAAKKEDKDATHAILSDFGAATLYGSAAGSQEGEANTLAGLEKLEVLAFAHLIEDVLGLMGRDDSTSSASAAVRVGLLSLHTRCIIPAVADRPVFSTIVEDLAAVQAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT96</accession>
    <name>A0ABR3YT96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enolase</fullName>
            <ecNumber evidence="4">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ENO1</name>
        <name evidence="14" type="ORF">Sste5346_007510</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="12">
        <location>
            <begin position="143"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1891595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="47615" checksum="17DD15F73A70FFA7" modified="2025-10-08" version="1">MAITKIHARYVYDSRGNPTVEVDVVTETGLHRAIVPSGASTGQHEACELRDGDKEKWAGKGVLTAVKNVNEVIGPAIIKEALDVKDQSKVDKFLIDLDGTPNKTKLGANAILGVSLAIAKAGAAEKGVPLYAHVSDLAGTKKPYVLPVPFMNVLNGGSHAGGRLAFQEFMIVPSDAPSFSEALRWGAEVYQQLKSLAKKKYGQSAGNVGDEGGVAPDIQTADEALELISEAIEKAGYTGRMNIAMDVASSEFYKEDVKKYDLDFKNPDSDPTKWITYEELAQIYSDLSKKYPIVSIEDPFAEDDWEAWSYFYKTQNIQIVGDDLTVTNPLRIKKAIELKACNALLLKVNQIGTLTESIQAAKDSYADGWGVMVSHRSGETEDVTIADIVVGIRSGEIKTGAPARSERLAKLNQLLRIEEELGENAIYAGKNFRTSVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI3</accession>
    <name>A0ABR3YTI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Translation elongation factor 1 beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EFB1</name>
        <name evidence="7" type="ORF">Sste5346_007726</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10308">
        <property type="entry name" value="GST_C_eEF1b_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018940">
        <property type="entry name" value="EF-1_beta_acid_region_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049720">
        <property type="entry name" value="EF1B_bsu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001326">
        <property type="entry name" value="Transl_elong_EF1B_B/D_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595">
        <property type="entry name" value="EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595:SF21">
        <property type="entry name" value="ELONGATION FACTOR 1-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10587">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01182">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00824">
        <property type="entry name" value="EF1BD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00825">
        <property type="entry name" value="EF1BD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Elongation factor 1 beta central acidic region eukaryote" evidence="6">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange" evidence="5">
        <location>
            <begin position="143"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="229" mass="25199" checksum="1A660633B1C191AA" modified="2025-10-08" version="1">MGFTDLLTDAGLAVLNSFLTTRSYIVGYSATQADVVVFKALKEAPAAAKYPNAARWYKHIATYEDEFATLSGDASKPYTAYGPEVAEVTINPAKAPAAEEDDDDVDLFGSDDEEEDAEAVRVREERLAEYRKKKEGKTKPAAKSVVTLDVKPWDDETDMKALEESVRSIDQEGLVWGLSKLVAVGFGIKKLQITLVVEDDKVSLDDLQDTIAEFEDYVQSSDVVAMQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTW2</accession>
    <name>A0ABR3YTW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PEX12</name>
        <name evidence="18" type="ORF">Sste5346_007650</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="17">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="301"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1891387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="469" mass="51214" checksum="C357807BFA90123A" modified="2025-10-08" version="1">MDANAAMVDEQKPSLFELLSEQQLHGLLPPTLRYLLTIATQRYPRYLLRALNSFDELYALAMVVVEHYYLKTMGGTFTEHFYGLKRERVLEGGTLAKNSEVPRAAAGTPAVIRTFLQLSRSGDLWRNLGVIVGVPYLKRKLDAAYELDAPRARLGAAYQRLPANPTLRDRIKHLARWFLRNVYPSVHAAYGFAVLAFNLAYLFDGSRYASPLLWLVSTRIRRMTGADYRAIDNLAEQRQAATNASGPRSVANRMLGGLSMVLPASIFALKFLEWWHASDFAKQLSLKAAANLDLPPPLSAGLPAGAPTKPSTAAISSNASNTGSIGRKGILKKEPSRRVEDAPVTPTNATTAAEGGEGETPADGPTEEEELARTAPIAKPSLLPIYTVPVPTDSALCPICTENITTPTACQTGAVYCYICIHKWVSGQHDKQEAFMADKAGRWESGEGRCAVTGRRVLGGTEGLRRLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUA2</accession>
    <name>A0ABR3YUA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ubiquitin carboxyl-terminal hydrolase 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ubp10</name>
        <name evidence="13" type="ORF">Sste5346_007631</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02669">
        <property type="entry name" value="Peptidase_C19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033809">
        <property type="entry name" value="USP39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="12">
        <location>
            <begin position="78"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="203"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="352"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="648"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="706"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="652"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="706"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="729" mass="79370" checksum="86D6B706FE73FEEB" modified="2025-10-08" version="1">MAKRRAAEDLDATEGVTSPAPKKQRNVDGRDGRDGREELLNGRTSLDEVTATEVNDGDDNDEEETAAPLRQAAPTAGYDDLYLDSIDRHVLDFDFEKLCSVSLSHINVYACLVCGRYYQGRGPKSHAYFHALDEGHHVYINMQTQRVYVLPEGYEVLSKSLDDIKFVADPRYTRSDVAQLDRRTATSKICYTLAGKPYTPGFVGMNNIKENDYLNVVVQALAHVPPLRNFFLLDEFSSSTASKTHTNAELVKRFGLLVRKIWNPRAFKAHVSPHELLQEVALRSNRRFTLTAQADPVDFLTWFLNHLHLGLGGSRTRPGSSIVQRVFQGKVRVESEKLEAVGASAAAAAAAKAAETNGGSQPSPQQSPDSMMIDAPLPVRPGGSMAPPPPPGMGSHPSHHQHQMPPPGLGGAPGQGPFAQMPPPPGVSSDSGMFNMPPPSLPPGVSSGMGQQQSSLPPSPSSLPPPPSFSQQLQSQQQQQQQETPSKTTTVAPVPTGPTVDISRFLLLTLDLPAAPLFQDEQERNIIPQVALTTLLGKYDGQSAHTARVDQSDVRRRFQLQGPLPPYLILHMKRFSVNKFITERNPTIVTFDPRGLNMRPYVDNATADDGDYTYDLVANVVHEAERARGDDVAVDSAEEKQTWKVQLRDRSGATAATTANGSTSSDSGDDKWVVAQDLFVEPVAGELLYLAESYIQIWERRRRPTNAAGAGANGKAKAKPTNGTGIAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV19</accession>
    <name>A0ABR3YV19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SEC4</name>
        <name evidence="6" type="ORF">Sste5346_007177</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="206" mass="22792" checksum="3FB3BFBF54D54E4B" modified="2025-10-08" version="1">MAGNRNYDFLIKLLLIGDSGVGKSCCLLRFSEDSFTPSFITTIGIDFKIRTIELDGKRVKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDERSFENIRTWFSNVEQHATEGVNKILIGNKCDWEEKRVISTEQGQQLANELGIPFLEVSAKSGINIDKAFYSLAADIKSRIIDTAKTEQTPTSGVNVSGQNGDNGGIGGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV25</accession>
    <name>A0ABR3YV25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-strand DNA deaminase toxin A-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057517">
        <property type="entry name" value="SsdA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24120">
        <property type="entry name" value="SsdA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Single-strand DNA deaminase toxin A-like C-terminal" evidence="2">
        <location>
            <begin position="88"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="741"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="866"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="894"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="915" mass="97843" checksum="4EA108DF96D6C0DA" modified="2025-10-08" version="1">MTSDKKSKLPKKKGNTGSTAKSRYKSDGDGNKKCKPKISFAWKDRGRKLVVMNELATAKTGLPGTSRIQATPACLIANGTSTPMKVCTSGWRKTPADGLNLDGEKWTKLVRDFCAVSNFTLRISVRDTPKSSERVPENEYRYDACHAEKKLGLYFFGKQMQFANMRIRDALDGQLLNAGLSDRRLGARIYLGHRPCKSCLDFLEHIRSMSGIYIKAVSCPVFAEHTRTRVFFNGTSTITGSFGGGGGPPDKNDKIKSLFGTDGHGSSSDEEDNDADDDDAAVKAIKARRSGDEADASSYEGDDDNEIVMSGDVESPDLLDAADEIIAGLPVGNIIRPRSPRSPCLSPTHRPRPLPNVMTPIRREPLIVPERQEEDSDSESRSPEPSVREQGVSAAVSVRSSVRSSPSPSFSLASVLNSSVIDPRDRFPEYTSPSRRGGSAAPPSIWGARHKPPTTPCLEPPDFGARQGNTTGGTNNGGVSSSWVAADNELSYFFGTPSAPSLLSDYAGPVEMSGAIAVAHGTFAAPLLVAESTLTPEASVMVPPPTPIPRVDNNGRRQMSEQPQTGNPIDLQLPPRTRLDILSEAAHAVSTGSVAQDLTGGSVSDIQTGEQNSAGEQEDSASSVVSVSAPSINVPAYLRQIARNQNANSSGNGATTTTNNDRPRQIVNGVGSANRSQFSGQAAAIIHAPRPRNPSGHSPVLATQTTFTVPVVDLTDDAEDRNDTASRLPFVRGQVENPWIRTAPVTQRQTTQTQPQNQTPAQTHPRPSRTQENQQPDVVLLSSHPALTRGVADIPRGGLNQNCNKNHGRREPSQTNLNRSPPRPTIINGSTPVNGNSRPRPGVAQPVRNRGGRGGRSGRGGGSVNRGGQPSSSSLSASRTRFPDLSEFVYYNGNNLSSGNDNSGYGTGRWGNGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVZ8</accession>
    <name>A0ABR3YVZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF4">
        <property type="entry name" value="S-ADENOSYL-METHIONINE-STEROL-C-METHYLTRANSFERAS (AFU_ORTHOLOGUE AFUA_4G09190)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="199"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="431" mass="47646" checksum="D99EA8A214FA5E7A" modified="2025-10-08" version="1">MSAAVISQAPAAAPATSTVRPGLLANDRSSTSSAQSSDTLYDAAEAKHLEPAAHKLRKQFFHLHHHHSSANSSKESVAVVEERSASTKRTKTFIKSFKYLNNLTPKQVDDFMASYVIYNLDWKDEPAMIAALGPDYKQRVGDSLRAYYGVMNHLCALGSVEKMYIPPLMDKHVSVLDNQLLYEESIARDLGLKPGDRVLDIGCGRGRVAAHMAKYSGAHITGINIDPNQLAQARAWNKEQGLSNTFVERDQNDLPLPFEDASFDAFYQIQAFSLCKDLPAMFREIYRVLKPGARFSMLDWVSLPAYDPTNEEHAELMRRVKPLIGAVGTPTPAGLEKALADAGFTVTKSDNASVGGLQAPLIDKVDIYFRAVRQMILGLVRVHVLPKHFKTLINRLCLDGQAFVKMDEMRLISTSYRIIAQKPLDAPATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW21</accession>
    <name>A0ABR3YW21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="522"/>
        </location>
    </feature>
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            <begin position="550"/>
            <end position="587"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
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        </location>
    </feature>
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        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
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        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
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            <end position="571"/>
        </location>
    </feature>
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            <begin position="645"/>
            <end position="666"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="697" mass="75753" checksum="AD2270BD06C69AE2" modified="2025-10-08" version="1">MAFHQPTRQAVQRPPREESQERVDTRVSTVLPAALEGSQTWVLFSPNADTETTSSVLDSLPESSQQTAGRSRLSDLGSLRSLEPSNYASSYAQSAIARPANLRLSLLTSAQSQSNNDEAIMSEDGRPDAEDDAELDSLDSHLPDFRFTAQQSQAQQVMAATATTTVNLPTHDGLGSFRLGNAIGMSSAVQEHLYAFEQFNPRRVTKRRRESLDLAQLQADDEFTEDIERTRRIEAWRWEHSRVLLEEIQKETRRRRGSELSARRSRASAAAANTKPAPCVVVSDGTAQAEASADWHDQEEDDRLMKLRKAAGEDGGEPNEGLWSRITRKFMLEVMGIDDRILSVLFGDDLAADEEQDDEMDLSSTPRASNPLLEAAAAGIESADVGDHEDSSSWQLRMLERIAKELGLFVHSHVNSHPGAFSTFKRVQQMPLPYAGLPVIPEAMTPAPRVLGSGREVGEASGEKTTDDITPTGTTASLPRFKPTIYQARPMDIPGQATESTNVPAPAASAAATSSSTTPTAPQAFTQDEWEQDLDIKLVFRYLRSRFFSGSGSASNHAHRHHLHHHAHHGHSSGGSGSINMNSQEAATKVARVRQHHPLVGRGASAARQTGERRPPMPAFRNMNTSGGVAAPSSPILGMRHGHGTATSCASQSTRRSARRSSISSRHSSRHYWDIGGSIGTGSMIASAGPMGSWGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW91</accession>
    <name>A0ABR3YW91_9PEZI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046696052" evidence="2">
        <location>
            <begin position="19"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="301" mass="30210" checksum="EF510B3E82A1A509" modified="2025-10-08" version="1">MKSSIALSTLLWAGPILAGPCRPSKPSSVSSVAAVSSSVSPVSSSLSVLHPPPSSSSVAPSFSDIVGTPASSSPVPSSFSSVVVVLPSSSPAPSSSAPAAPSSSAAPSSAPVAPSSSTPSSSSSAALPSSSGGLTTNPGQTCSTTNLFQDSDFSLGLSYWPSNILSGSPTCSLGANCGSSTSGAAYAACLELDLVTLGKAEGIAFHQEVTVVKGTYYTGYFHYRLPSLGASGSSMATLTCTMNGVTKYSIVLCDNDVSQTYKTVNFSYTADCKEATFQCKVTTSAVTAQLQFADFYLGAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX59</accession>
    <name>A0ABR3YX59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006654</name>
    </gene>
    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018287">
        <property type="entry name" value="Hap4_TF_heteromerisation"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF7">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10297">
        <property type="entry name" value="Hap4_Hap_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="533"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="710" mass="74809" checksum="153BE1104F4FA1C1" modified="2025-10-08" version="1">MKSPLPTAFSPAPLASAYSSKSSTPMSPASPMSSHDSPKPSTSTSISSTSSTSVAPKPQLAIKPVAPSPAGTTPAVRPLQMQIAANSPGGNVMSMTSVVSPMAAAQSPATAQSPISAAGKPPMSITSKEWVIPPRPKPGRKPATDTPPTKRKAQNRAAQRAFRERRAARVGELEDLLEDQKNEHDRAERESQDKIRTLETEVQVLRSRCQMLESLLEKEKATNQAWSTKERQASQSSARSNSMHRNNSIQPQQTQHQPHQLQQQHQHQQSLSHIHSPVPHKLLQHDQQRGSTSSSISSASGRRISAQPFSISQIISPPDDEELTCGNCNVNGTCACADEVMAATVSMDCGKCTLGTKCACLEASINALTGGGFSNVPSELKRSHSTSSPTPLAPEEKRARHFSDIDASTEIDFTHMFSRPKATPVRTPLPSMQPRHQPQPQQQIQQAAPGFEIPLKERCGFCSDGTYCVCADSMPGVTMTGSLAISAGTVVAQQKTPPPSETDLAPMPLEVTATGAIKLSSMAALRKQKQEASKLAAPTSAAAPSEAPRSKCGPGGPGTCAQCLSDPISGLFCRSLAANFDRQGAGGGGCCGGGGAGGGCCKDKKAAAAPANPPISTAPSSTFVGPNGSSLTADAAKKSISLSCADAYKTLSSHRHFEEATDEISTWLPKLRAAPRHDPNQPAARHPMEVEAASIMSVLKGFDIRFGKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY00</accession>
    <name>A0ABR3YY00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006903</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF30">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04702)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="550" mass="61014" checksum="E542571812F47B5C" modified="2025-10-08" version="1">MDVSIEHRESPGTVTLVDLAGTIDAKHSSSQKEIILSPTPSADPNDPLNWSKWRKWRTTLCTLLFTWCVCCSSSACFSVFVPIYEQSGISLDHLNQGTGYMYLLFGWSLLFWQPLALTFGRRGVFLLCLLGTCMMNVWAGYAVSNGTWIASRILIGFFGAPSEALAEVVMADLWFAHERGTYMGLYVMSLYGGQLAAVPAGYITNAMGWPWVLWWCAILNAVGFVICFFLLEETMYHREVLPTTNHVNHSNAVSAGSADAVNATEKDLSAKRTDAGVMDSSDGSLRGREMISAGTSYPVRSYWQKLALFRSLDGRRNTVWEQAYKPLLLVRFPGIVFGGFIYGCYLNWFSIVNATVSIFFSSEPYTWSSASVGLSYIAELLGTYLSGFVAGRLADRITIALAKRNRGVMEPEFRLWLFALLAVLAPLGLFLYGIGFAHSLSYWSMLFGMVMIGFVGPACGSLVVSYIVDCYREISGEALITVILIRNTMNFGFNYGVTPWVDNMGAQNTFLMAGVIAFATTLVFLIMIVWGKKMRMANAAAYWKFVEEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC6</accession>
    <name>A0ABR3YYC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPS2</name>
        <name evidence="10" type="ORF">Sste5346_006809</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="88"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="28756" checksum="B0E5F48A88DF0B27" modified="2025-10-08" version="1">MADRGTSAPRGGGFGSRGDRGGDRGRGGRGGRRGGRRGGGKNDEKEWQPVTKLGRLVKAGKIKSMEEIYLHSLPIKEYQIVDFFLPKLKDEVMKIKPVQKQTRAGQRTRFKAIVIIGDSEGHVGLGIKTSKEVATAIRAAIIIAKLSVIPVRRGYWGTNLGLPHSIPTKESGKCGSVTVRLIPAPRGTSLVASPAVKRLLQLAGIEDVYTSSSGSTKTLENTLKATFAAVSNTYGFLTPNLWKETKLIRSPLEEFADTLRDGKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z167</accession>
    <name>A0ABR3Z167_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">glucan endo-1,6-beta-glucosidase</fullName>
            <ecNumber evidence="13">3.2.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-1,6-glucanase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Endo-1,6-beta-D-glucanase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Endo-1,6-beta-glucanase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Sste5346_006073</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Random hydrolysis of (1-&gt;6)-linkages in (1-&gt;6)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.75"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.75" evidence="13"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF39">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046422335" description="glucan endo-1,6-beta-glucosidase" evidence="18">
        <location>
            <begin position="19"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="19">
        <location>
            <begin position="99"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00036633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00043257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1893932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="416" mass="46447" checksum="061B6C6490FBAC43" modified="2025-10-08" version="1">MSKVSTLAVAALLGSAHAWLPNENLHRMEARDGSNMFNVSSRRSVEGRWLTTDGAPLRGVNLGSQFVLEPWMASNSWSSMGCSGQNSEFDCVSLLGQDAANSAFQSHWGSWITEDDFNEMQSYGLNSVRIPLGYWLDESLVYSDSEHFPQGALSYLTQIVGWASDRGFYIILDLHGAPGAQVATNADTGQYASTPGFYVDYQYERALQFLEYLVTQVHTVNEYRNVGMIEIVNEPLQNTDDQTTSMRSSYYADAWNRVHAKEDDLGVHGNAQVHLAVMNDNWGSGNPVEYMNSWYVAYDDHRYLKWDSSVSVDQASYLAASCNDASQSDSPGIVGEFSLSPPDDVQWTDAWTPASNVDFYAKWFAAQMTSYESHNLGWFFWSWKTELGDYRWSYKDAVAAGVIPADLSTVNRASAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1A5</accession>
    <name>A0ABR3Z1A5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="199" mass="20219" checksum="6EF2E677ADD14F8B" modified="2025-10-08" version="1">MSSNNSPESKRRVSFSIQGGHPVVPVVPLALAPATSSAPTVTSSPVAAATTAVTLASSSPVLSSPVRTPASSPLDKDKGSGSSKTITPTKASPGAATPTKGTPTKGTPKETKVPVPAVPGTLQPPTPQKPTTEALRGALQEVLGNNSWGKNKECLKKSPPPRRVPNEISPISTAATVAPIPIRSPLPTKPKTPTKSPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1R0</accession>
    <name>A0ABR3Z1R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="355" mass="37343" checksum="705D9AAB945F3B65" modified="2025-10-08" version="1">MAHQHPNSNTGLPIRPSCQQENADFEGAVDSTSQFPALSDITNLTSTNAATIDAHGSDDEGGFMHMSDDQLARDSETTNLRGARNRLWGTEVDQHFDAAAFGQAIEKPCSKAASNTSDPSGTSVTFGPSTSSAAARAARRMARRVALSANIATTDILGRLINGSARAPGQICSWVSSGFSSPSSASDSTNVTAYFDINDDSVFQPSVSGTSPSTISTTRTMARPSLSPSMYQTPPTSCSGSANASSTNVASTTDESLDSTDYQAMVAGTLFERGPDGNIVPTSLIQGASGAVEHEEIDGFEMIFGRDEATARTAPTTHEHDHGHDDAHSLNRDNEVVDETFCVIGTTRPDNEPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1U4</accession>
    <name>A0ABR3Z1U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="123"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="396" mass="43523" checksum="42DEAF2730516697" modified="2025-10-08" version="1">MAASFFKYASVSVAAVVGLYAALLGLLTTSIFQSHAVYLHAIQMTWFKDLNVPESFGFLRNQVTPFSIKTPDGEQLYAWHVLPGELYRKHELSLVAEPAGHVSDITSRLAFQLLRDDPEARLVLHMHGAGGTVGSGYRVPNYRALSAGQPGKIHVLTFDYRGFGRSTGSPSESGLIFDALAVVDWAMNVAGIPPSRIVVFAQSMGTAVSIAVSKHLALQSPPVVFAGTVLVAPFSDVATLVSTYRVAGTVPILSPLARFPWLFKALHHFIVDKWPSKDRLAEYVRANERNEQDYRLTVIHAKDDYDIPWSHTPVVFWHAVNASVPAGISHDELELIKLDSRRDLGAAGTVMEWKTDHGVIREEILETGLHDVIMGYPVVTMAVMRSFEAADPSFKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W0</accession>
    <name>A0ABR3Z1W0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8131" checksum="8682AA672B8E7AA6" modified="2025-10-08" version="1">MSNSSNSEPKFSTQVEDPNKPDAPKHQHGLFEAAKDKFSAHQANPGPAIMNSGSVPQEGTKEERRAKAEALNKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Y5</accession>
    <name>A0ABR3Z1Y5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="361"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="656" mass="72486" checksum="D057792BA3F181E6" modified="2025-10-08" version="1">MEPAEQTPSLPTRRRKFRIKSKFGEPRQWRSRKKSDRDGGYDGDDTGPAFATPGPLSVPLPLQLPFPLPSPISVLVDAAMSRADADGTSPCFVEDHIETAPPITVISQLSAIAPLTSATPCARAQSSPGRFSATADRTAIYTLDDNEGLTAHSMGLSGEQDTELLASFRAAVMNEADSVDIDILQVYAGGDVDRDGESHPPVHFNMVRDEFLPLDNAAKQASSDRIETAVQGCADGLIRLYFKHVHPVFPVLSKTRFLKAYADNRQSIPASLRGAVYGIASNFWHRDPNHSQEQSQTCGRSASPKLCGASISHLDQHELFEQALASLQRELHGPNLWTLQACLLLIHENSAENATVETPRVWMLAAQAVACAQLLGLHRDPMAWQIEAWEMHLRRKLWWATFSTDVWSSVCHGNPPHIYPGSFTTSPLSMEDMAHDENVPASLRHMVDEDCVSSDTAVCARFTNAVSISRIVHELLLSSFLDIAYLESIKDQLSREVPLLQIRRQLQDWSMLLPRCISMESIPTANVYHSNAPLHLSYYAAVALNFRALMSPVTKAAKQDPGSSLRRHFCSAIKDFASFIDFMHGISPDCLHSFWGLHQVRDTFALLGKFHDSLQRLSAIADEFAIGVLRPVALRIDSFFTQAAQVMRTNGQSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z298</accession>
    <name>A0ABR3Z298_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sphingolipid long chain base-responsive protein LSP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028245">
        <property type="entry name" value="PIL1/LSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962:SF4">
        <property type="entry name" value="PRIMARY COMPONENT OF EISOSOMES (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13805">
        <property type="entry name" value="Pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32333" checksum="1FD4B4CC3D4BEA09" modified="2025-10-08" version="1">MMNRGLSIRSKGSSNKSRGGGGTSGGFSFSSLRGVSQPELSKKLYRLIKSENNLISAHETAGRERVSIATQLSEWGEQTNDDAVSDISDKVGVVLSEIGEQEDQYAHALDDSRAVLKAVRNTEKSVQPSRDNKAKIADQIALLKTKEPDSPRLVILEQELVRAEAENLVAEAQLTNITRQKLKESFEAEFAATIERAEKQIILARHGQRLLKLLDDTPVVPGDTRAAYQYSGQARQILNDAEDDLREWQPEIQDDDAEANGHEGSITGNGHTEEAGAEAEGASAEGVAVVERVDGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D7</accession>
    <name>A0ABR3Z2D7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U3 small nucleolar RNA-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">utp13</name>
        <name evidence="9" type="ORF">Sste5346_005741</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ASTRA complex involved in chromatin remodeling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013934">
        <property type="entry name" value="Utp13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF15">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08625">
        <property type="entry name" value="Utp13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="107"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="443"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="562"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="723"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 13 C-terminal" evidence="8">
        <location>
            <begin position="812"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="906"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1000" mass="107664" checksum="B3F78AB9A651779A" modified="2025-10-08" version="1">MATKLAYKTTFEVDQVIRPIYTGGSVALDNGSRILASTLGEDAVLTDLSTGKLFARIEGDGEPISTLTLTPSASHLVVCSRSLAMRIYALHVSEDLEAVEPTLLRTLKPHATPAVVLAVDRTSTLLATGAADGNIKVWDIRGGFVTHTFRGPSVLVSALHFFEVAATNAGAEVVQDGKKKKNKKAAQQQQIQETAAADETSTRFRLASGSQDGKVRVWDLHKRAVVANLDAHVSDVQAIDYSPAQNVFVTAARDKTMIWWDAKTWTQRRVVPTFELIEAAGFISSDSVDKNTDDDQESGAVTYSAGANGCIRLWETRTGREITAEQTAKSDEESIVAAIFRPAQSTLLCVQMDQTLALYPVPSSKDLLKAFASKSSTGLSPLEPSRRISGTHDDVIDLAFLLPDQSLLALGTNSEDVRIVSVADPATSSTPNSAYFGQDVALLKGHTDIVVTLDVDWSGHWIATGAKDNSARLWRVDQSAAAAGGNKEYSCYAVFAGHAESVGAVALPKAVPEPGTPAFEDPLSHPPQFLVTGSQDLTVKRWDIPRQAPTSSSAQQRALFTRKAHDKDINALDIDAAGQLFASSSQDRTVKIWSVREGEVQGILRGHRRGVWSVKFAPLHTPSLTSDTGTVAGGSRGFVLTGSGDKTVKLWSLADYACLRTFEGHTNSVLKVAWLGNGDNKEEETKEEEEEDAEDDEYMDLDDDEERPSRRNASANRGPAPVLFASAGGDGLVKVWDAASGEAACTLDNHEDRVWALAVRSPAPTAVTSTKKRLPRMFVSGGGDATISFWRDTTASTVAAAAEAAKERVEQEQQLANHMRRGAYREALTLALQLNQPGRLLSVLSQVGEYGANPGVDAALASLTDDQLYLLLLRVRDWNTNGRTATVAQRVLASIVRSYPATRLAGLSRRRHTKPSENGDGPVVDDISAGGVSSSIRGANIKDVLDALLAYTERHYRRMAELLDESYLVDYTLQEMDALQMPGGPTIAGEIEDVAMAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2G2</accession>
    <name>A0ABR3Z2G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SKY1</name>
        <name evidence="12" type="ORF">Sste5346_005888</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="116"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="272"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="291"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="601" mass="66104" checksum="CA9345F5F5027B99" modified="2025-10-08" version="1">MNGATSSAEPSAAQSKPQTDPTPAAATATPAAPASASNGDSAANSGSIKKRKKDALKPIITTEGSSHISGLNHSPTSSSSVDDAADNTADEEDSEDYCKGGYHPVQIGEKFKDGKYTVVRKLGWGHFSTVWLSRDNVTGKHVALKVVRSAAHYTETAVDEIKLLNKIVQANPDHPGRKHVISLLDSFEHKGPNGTHVCMVFEVLGETLLGLIKKWNHRGIPMYLVKQITKQVLLGLDYLHRECGIIHTDLKPENVLIEIGDVEQIVKKVVKTESSDKENNRNGRRRRRTLITGSQPLPSPLNASFGHNTPFATPGSHSSLGQMLHDSSSHSHKKDFSSSEHDMDHHKDEGIEEFQKKREKTEDILAKEVSSVSLGKSSSTHSSSSSPSSSGDKRKAEEHSLNIDIISVKIADLGNACWVNHHFTNDIQTRQYRSPEVILGAKWGASTDVWSMAAMVFELITGDYLFDPQSGTKYGKDDDHIAQIIELLGPFPKSLCLSGKWSQEIFNRKGDLRNIHRLRHWALPDVLREKYHFKDEEGRRIADFLLPLLELVPEKRANAGGMASHPWLEDTPGMHTVAIDGIPVGSRGEGIDGWATEVRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Q4</accession>
    <name>A0ABR3Z2Q4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="485" mass="53064" checksum="95ECE25A00E51B26" modified="2025-10-08" version="1">MRPSCMTEDQKYQGALYKDNNNKNNKNNNKKARINPPNGADEEHHFHPSTPAAPSASTNNSNNNNSNKNNNSKQQVASTPSVKKSNMAAVAQYQQSHHMSHAAYVEDVPEALESYLVADDDDHRSDDDAPPHAPTPPPAAEGPVNVFDFLVAGATPNASSLGLSQPAVKFQDNNDASRYGYDDANAYLAATTDDFSMAGHAKYQQHLAQYGNTGPVPTPAEPMSTALTPFKTPAPDRAERKKKEKESSGDKDKDASKKDKKRKRLYLDINDQVMTDAPPVLHSGLTGGLHRLTTKHAAFPPSPESAETPASPLKKSKSKHSKTRTEPVTNSLFSMLTAGGSKSSKSKKRKHRRSASPSSGKKHSSSKSHRKHRGDADKDGEPKAAPQKLLEYPGAEKKDDDKNDGSGQLIVYKPRADLFLSFVNKGPDSERGCSMNKALKRFHRERSSSGTSLAKPAEEKELFRSLRLRKNDRGEIVLFCVDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K5</accession>
    <name>A0ABR3Z3K5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone (DnaJ superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SIS1</name>
        <name evidence="4" type="ORF">Sste5346_005748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="384" mass="40874" checksum="402713221BD21C94" modified="2025-10-08" version="1">MVKETKLYDQLAIKPDASQDEIKKAYRKMALKWHPDKNKDNAAASEKFKECSQAYEILSDPEKRKTYDTYGLEFILRGGVPYEGDADGGAGGFGGAGMGGMPGGFSGMNFGGMPGGGGSTRTFNFSTGGGPGGANGFKFNAPNATFADFLRTTGAEGLEDLLGGGLGGGGFSGGGMPRSARSGGGASFGGVGGGDDPFGRSARHHTPEVTTVERPLPVTLEEMFNGTTKRMKIKRKMYDESGKRTTTDTVLEVPIKAGLKKGSKIRFKGVGDQEEGGQQDLVFIVEEKKHPMFTRDGDDVVANVDLDLKEALTGWKRTVSTIDGKQINLDKSGPTQPGSSDAYPSLGMPISKLPGQRGKFIVKYNVKFPTTLTPTQKQKLREIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4U8</accession>
    <name>A0ABR3Z4U8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="948"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="967" mass="106696" checksum="568C03A8E930464D" modified="2025-10-08" version="1">MAHRGKRGGRSHKKGKNKNANADRAASAPAEMQTNSVASDHQETLVNPVVSLPQQAQGSGDNGGEGPFSPPFVSILGGPIYASPVQMSDAQLARFPRGNDLNKDVSDLELTEPSSVDGVEKKNKGKGKATCGDSSDELATDPSSSDDDDDDDDDIPPSKSDKAKGKQLAYKTSANGQSSKSKAAKGKGKENCPPVTPLQQVDSDFGGGSSSTAVDDVWHPGHRTPPSPSPISIPYVISNGIAQENVFGPAAPCPRPRPRPHVQHQHRQQCGLPRLRHGPVRRVKYSTAMTAMPCAQTAQFEYAGPSSSSQNVNDNIHGSTSFNLPAGLEIDADGNLLIILVNGSMDNELARFLVDAHMFSTTSLVWMGVLKQWRAQVIPLQPQDMGPHTSVMHDFAQYGPAAQTMVRREIRQMLGRSVSNDIVKRITHSILYGERSYSGFPFPVVDSFCQRKRNDRIFCCNQGADNGFGFCDTHEFKQLLGTITIDIAPWLEQGVSPWDAIIAFLTTLTAARGNIDQIGELPFPLTISGTAALLDLTVRTQIGIPMRFVTDNRVATFGITERTSLYHVGPFAYHMHRHLVHFNQMGQHLRILYRETLLTHMFLHEASLSKMLIYWFTRERHAFELTLRHVAWQTYVTVADNNDDDINGNGKKIRLHHVHLTLMNTAHGPGNAEDGTNSLTVPPTHLMADFIATTRRGFLHQLYRIANASFAQLWYHVQSSPHGIATCPKSNIKMKRTANCTIPQFKCKSSTASDVDKAKCDHAHLNALIQQMHTLTTPGFVPIPFADSVGNAHPNANPPHFVLNTEVNKWLGTPYSLIGYIGETIRKVHEHAIAHLWEVLDMPWDARMHSDCTGSLESAVEDCEQFLYETRQFPESALYPFTVMSQQMEDQMRTNHTLLFNVRLSLFDKDDAVVPPGEDQRTATEVQNLLNRVFLGMIEEMGLRVVENEVESSDESASASDETDNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5W8</accession>
    <name>A0ABR3Z5W8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">vps35</name>
        <name evidence="8" type="ORF">Sste5346_005122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the VPS35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.660">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005378">
        <property type="entry name" value="Vps35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042491">
        <property type="entry name" value="Vps35_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03635">
        <property type="entry name" value="Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009375">
        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="909" mass="101284" checksum="650FE811714465BD" modified="2025-10-08" version="1">MAAPVVADDQARLLEDALIAVRQQTVLMRKCLDTPGKLMDALKCCSTLVSELRTSSLGPKQYYELYMAVFDALRYLSVHLRENHPVNHLADLYELVQYAGNIIPRLYLMITVGTAYMAVEGAPVKELMKDMMDMSRGIQHPIRGLFLRYYLSGQARDYLPTTDSEGPEGNLQDSISFILTNFVEMNKLWVRLQHQGHSREREQRTQERKELQLLVGTNIVRLSQLVDLETYKNTILAPLLEQVVQCRDVLAQEYLLEVITQVFPDEFHLHTLDQFLAAVSKLNPHVNVKAIVVGLMDRLSNYAEREAQNRPNENREKIEEDALVALLNKTKLGGDSGTDGAQAAETTSDGAAGGSRSASPAAADKDETNDDDAQSTTDTLATEATAETEATAVNGGDNNGTAEGDVPSTDGDAAASRGIGGDIHLYEVFFGQVKQLVYAQHLPIHDTIALLVSLTNLALNIYPSRLDYVDQILDFATQKVQENVKNPDFHGQAAQQSLLALLQAPIKHYVSIFTALALPTYVPLLQSQIYQTKRAVAGEVARSLLRNQTRISTPEQLTNVLDVLKVLIVEASPAPQGPQRGRSYETDETLEEQGWLARIVHLLNAEDNDTQYKLLQLARKAYADGNERIRITTPPLITASMKLARRFKAREHYDDNWKSQSSSLFKFMHSAVSTLYQRATNGNTAGGSSGGAELAFRLFCVCGQTADIVGFEEVAYEFFAQAFVVYEEAISDSKAQFQAVSAVASTLHQTRNFGRENFDTLITKCAQHASKLLRKPDQCRAVYLASHLWWATPIASNSETEENTESLYRDGKRVLECLQRALRVADSCMESATSIELFVEILDRYVYYFDQQNESVTTKYLNGLIELIHSNLASNQQESASVEASKKHFHHALELIRSKEYEGIVLTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z620</accession>
    <name>A0ABR3Z620_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase C13 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="44519" checksum="2D7A5B8EB2AC56A0" modified="2025-10-08" version="1">MSTPRASLTMNGHVVDEQLRTRQFTTKTPPRVTPGTRIVAATHPTFRIAGPGIDDWFLSDFYAFNYLLHGQGQSQIWLTAAKPETLLSKCGNYLHGNPFRDRKIVLSTELLQSGELTETTFVPASEMIGKFLAEVKTATEEAKRDGGAVLLLLFCHGNDDCSMILDAGESTKLTITRLQGVLEPYVPVCLLTTACYSGGWTVSKDINITTMTAATTQQQSLSWPRSPSIGRACGSVFIGSIIPAVGKAAKTFPEDDNQPLSAMALTTGSSEIPSPNPGKPQQVSTYNSLCRSVWQFCQDQHRLWTEHHFSFSAQGDEWEEPWSRMTGMALEEYEARWAKLVTVPYTGSAETKSHLDPSPDNSYFLGASMRTVATGGHRPSHDRTYDAFVGPFLESLHSNNVKAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6B8</accession>
    <name>A0ABR3Z6B8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="109" mass="12802" checksum="8D9036C4D11B6F4C" modified="2025-10-08" version="1">MAKKSKNKSLAFRRWEEYFNEDELDHWQRLMTILDIEGHFTSKTQCKKALRSVWVNIRDFLEAAAADKPVRQFRNRHAMSFYTETTGRYYARKKVVSGSPLAALLATID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6E2</accession>
    <name>A0ABR3Z6E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005506</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="261" mass="29372" checksum="B2D1F65CBA346C11" modified="2025-10-08" version="1">MSQVPVQSIPRDPQLLYWILFPITIVMILTGVLRHYANVLMATAPKKVEQRALREQRSMLHGVNVRTNHHVLSKRSFNTRRDNLVAAYESGAYLKAPENRGQAPPNPMTDPNAMDGMMGMMKGNMAMIIPNTLIMSWINAFFSGYVIMKLPFPLTIKFKSMLQAGVATRDMDARWMSSISWYFLCIFGLQSVFNFLLGNENAASQMAQQMGQMGPQMPQMGAPGQDPDKQFLAEVENLAVVEHYSVLDNVEQRLLSRASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z721</accession>
    <name>A0ABR3Z721_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS7</name>
        <name evidence="13" type="ORF">Sste5346_005087</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CHS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="332" mass="36867" checksum="17BB34D37EB5ABB0" modified="2025-10-08" version="1">MGFGDFTSLCRTAPIPLCASVGAITSISFGVGIEPDCYARNIELANTIIFQGAASAMHIVALLMTIIMIFHVRGKFTAVGRKEITTFFYIYLLLTFFSLIIDAGVVPPGSGPYPYFVAIQSGLASALVTSLFINGFVGFQLYEDGTPLSLWMLRLCSFAAFVISFLVSLATFKSWAGLGPTNTVGLFVVLYLLNGIQLLVYIVLQTILVLRTLQDRWPLGDIAFGVFFLIAGQVLLYAFSSRICVAISHYLDGLFFATTCNLLAVMMVYKYWDSITREDLEFSVGTRMNNWEVKELMPEEDRRNTIYTEDPYGQSSAYDHGYSPTGNRFSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7V0</accession>
    <name>A0ABR3Z7V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045280818" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="23335" checksum="45EFFD552BDE499A" modified="2025-10-08" version="1">MRTRSLFALGGIVLSGLPVTVASACRRGPHPSLSSSVSSTAPSASPSTSPSPPAACSNLVQNPDFSNGLTGWDQNSMSHGAYSVTPSTSCGTSAGDPASCAVFYAYTADIDPSFAATYQSNLPVTPGSIYTLYFRYRLVGNDAPSHMFTRINDVQSNGAVFNYNYPGGGPWAWFSTVWTAPTTPSTNFPDTTKAAITIILSTDGETTAWISDVKFDACVEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z827</accession>
    <name>A0ABR3Z827_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">acl1</name>
        <name evidence="13" type="ORF">Sste5346_004448</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="12">
        <location>
            <begin position="43"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="664" mass="72096" checksum="6563DC3A66C68E78" modified="2025-10-08" version="1">MTAASAPAGANGTKTPVGLSANDNITRFAAPSRPLSPLPAHALFNEKTRCFVYGLQPRAVQGMLDFDFICKRPTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQEVSKAMAKHPDVDVVVNFASSRSVYSSTLELMENPQIRTIAIIAEGVPERRAREIAHIAEKKGITIIGPATVGGIKPGCFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIISQNTDGVYEGVAIGGDRYPGTTFIDHLLRYQADPDCKILLLLGEVGGVEEYKVIEAVKKGVITKPIVAWAIGTCASMFKTEVQFGHAGAFANSQLETAATKNKMMREAGFFVPDTFEDMPALVKSVYEGLVKKGTITPSPEPIVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEDIGIGGVMSLLWFRRRLPDYASKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISALVSGLLTIGSRFGGALDGAAEEFTRAFDKGLSPREFVDSMRKANKLIPGIGHRVKSRNNPDLRVELVKQYVTEKFPNHKLLDYALAVESVTTSKKDNLILNVDGCVAVCFVDLMRNCGAFSAEEAEDYLKMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYLLPQLNAGPPGAEGRVEVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z885</accession>
    <name>A0ABR3Z885_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBC11</name>
        <name evidence="11" type="ORF">Sste5346_004509</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23791">
        <property type="entry name" value="UBCc_UBE2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="174" mass="19011" checksum="8FBA06F6DC52268B" modified="2025-10-08" version="1">MADAQSASDMQASVLGGAKKGPDSQSVTKRLQTELMMLMTSPAPGVSAFPSADGNLMSWRATIEGPDDTPYATLTFKLSFAFPANYPYAPPTVLFKTPIYHPNVDFSGRICLDILKDKWTPAYNTQTVLLSLQSLLGEPNNASPLNGEAAELWDTNAEEFKRKVLGRHRDVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9L6</accession>
    <name>A0ABR3Z9L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCH1</name>
        <name evidence="10" type="ORF">Sste5346_004224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="9">
        <location>
            <begin position="149"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="36118" checksum="776415BC6BB0E832" modified="2025-10-08" version="1">MADNEASDDVMALPHVNGDKANKSGAATPTNNNDDAKNANNNGNNGNNASGNGKRRRHKSSSAIRRAAKRRHSMSKAARDPRDEPESSTSAKAVTRTPSPDGGKQSAVATRSPSPFIDFDGLSRPSTGTRARLEENEEERAVRLEKMRGAVRTILECVGEDPNRAGLLGTPDRYAKALLDFTQGYQQNVREVVNGAIFHEGHNEMVIVKDIEVYSLCEHHMVPFTGKMHIGYIPFHSVIGISKLPRIAEMFSRRLQIQERLTKDVANAIMEILAPQGVAVVMESSHLCMVMRGVQKTSATTITSCVLGCFERKEKTRNEFLSLVGVNRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9M6</accession>
    <name>A0ABR3Z9M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyltransferase family 28 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="69"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="465"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="902" mass="96117" checksum="60B37FAB81522234" modified="2025-10-08" version="1">MSVQHLKLSSHSGFEADATVTDDGRVDIAVDETDPGKLAALLASKPLPTPPSTDEPSGTIDTKPPRLDIAIQVVGSRGDVQPFIALGHVLRRTYGHRVRLVTHSVFKDFVETPLTEGDGDGGHLEFFDIGGGDPAELMSFMVQNGKAGEKGDEKGEQGEEDNGGGGLIPPMESYTNGEIAGRRRFIEAVLHGCWRSMADNGGNDDDNDQNNENGTKEAPFVADAIIANPPSFAHIHIAESLGVPLHIMFTMPWTPTRSFPHPLANLKCMSSASSFPSSSHESSVYGFASVISYTIVECLAWQGLGDIINRFRSRNLGLEPLSPLLAVAPFHQGGLMGRLRVPTTYCWSPALLPKPKDWGSEITVAGYFFSALTSHKKDKTKAIESGYTPQPDMAKFLDAGPPPVYIGFGSIVVDDPAGLTKTIVDAVGRLKGVRAIVSKGWGGLGGDDADKTKSKDIFFLESDCPHEWLFPRMACVVHHGGAGTTAAGLRFGVPTVVVPFFGDQPFWGSLVAQAGAGPDPIPFSRLTSEQLATAIEQALKPETKTKAAALGDKIRDDKDGGGAVVGAKSFHEHLGGPDIHCEFLSDRLAVWQYKDKETKTTMKLSALAAAILVHSDKLAYSDLTLFRAQEYHIHTGDQPWEPITGAGSALLGDLSSIAMAVADFPLQLFKKAKKVEEEGKKTGEKLKEKLDETSTTIKVDTPSATVTLDTAVQAGQSVSRIVSTGLQTPLHFCLGLARGFHNAPRLYSDETVRNLPGTEDEPAVDGLGGGIKAASKAFGLGLYDGVTGLVTQPLKGAEEHGGKGLVKGFAKGIGGVVFKPAAGAWSVPAYTMQGFQAEVQKLTGGVGISHGASKKEMQARRVAARTRQSEAEWKAVESGEKDTVLKQWAETGIDVKKAESKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9X1</accession>
    <name>A0ABR3Z9X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-ornithine N(5)-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF2">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE AUSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="73334" checksum="2395F23FA7B9B027" modified="2025-10-08" version="1">MGSVTENGVNGAAPTSFVELSEKYKSEHDKRLRSDGLSQFTDLYSIPKFRRFKQDPWADRSTYDTLPRAFDGDRREILIMGTGIAALVFAVRLLEAGFKREDLQFIDVSAGFGGTWYWNRYPGLMCDVESYIYMPLLEETGYIPKHKYASGTELREHAERIAEKYDLTEQAWYRTRMVDSVWDDTAKEWVVRLAEQLSDGNEREPITVRSRFVILTTGLMLIPQVPQIKGIQTFAGDCFHAARWDYQVTGGSQQDPSLVNLKGKKVGIIGTGASSIQIVPELAKWADKLYVFQRTPSAVDRRDNRPTDAEWFKKEVSTGPGWQEKRSQNFYSFVSNASPKPEVNLVNDGWTTMPSYSALIGNTAHNPTTPEEIGKYYQYIKELDVERQSRVRDRVDVIIKDPATAAKLKPWYSGFCKRPCFHDDYLDSFNKPNVQLVDTDGKGIDEITEKGLVVQGQHYDVDVLILGTGYKSPFLFSPPGRVGVQILGRNGADLDKKWTNAVTTLHGVMSHDFPNMFWPGFIQAGGNPNYTYTINQGALQVAHLMGSGLKKTGSTTPASSGSGSSLYKYNFTVEATAEGEENWSMAVVSHAHMLGASSGCTPSYMNAEGELEGVSDPAKLAKMARSAPWGRGQADFDRVLDEWRAKGDFEGVEIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAT8</accession>
    <name>A0ABR3ZAT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004016</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="9"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="24042" checksum="811C1A73D080AACD" modified="2025-10-08" version="1">MPPTIAPLELTLVVAATARDMGIGANGGLPWTGLRKEMAYFARVTKRGEGNAVIMGRKTWDSIPPKFRPLRGRLNVVISRSFAPGLPKDPVGGPDAAPVEASSLEAALEYLRSRTAAAEATEAAASTPNRVFVIGGAQIYAAALGLAEARRVLLTRVQSDFACDTFFPLALGSGATTEITTDVPKWVQRSREEHAAWIGEEVPEGNQTENGTEYEFQMWERVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBA1</accession>
    <name>A0ABR3ZBA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17033" checksum="47500AAC47BC7927" modified="2025-10-08" version="1">MVDLTSPEILTAEIPATKISDDPDAEYAIDSTANSRDYYGNRVTVRKQREINEEDNRSFRDRRAKEDQRIASLRAIFPVAFSIPQEVYTKAAKDHKSLTEAECALLRSRDDLYGRALADPDSLTRGERYQILALLRLHPGHQGRKGLSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBH4</accession>
    <name>A0ABR3ZBH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase/reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF66">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="32487" checksum="6F66378180C67840" modified="2025-10-08" version="1">MVVNVEIDPAVLAAAAGQTAIITGAAGGIGAATAALFSQHGANVVIADLAGARAAANKLIPTLAHPDKAIFVPVDILNWADMQNLFREAVAKFGRVDVVVANAGIMETSPVLNMDAVDADGNLLESREAFKVLDVNIKGTLNTIRLGIHTMRQNEKKDGQLVAGSIVLVASTSGYFGGTSVAGYITSKHGVVGLLRSCRATATQYGIRINAVAPFFTPTHITASYADAWKAAGLESNTPTDVASVIAQQALNTEVTGTCVLACGKIRRELETTRAALVTQWMGEDVTTLMAEAGKLFAKLGGYPLPKKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBQ5</accession>
    <name>A0ABR3ZBQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SWI/SNF chromatin-remodeling complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SNF5</name>
        <name evidence="7" type="ORF">Sste5346_003985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="792"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="802"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="848"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="869" mass="94037" checksum="8ACA1EA68C5E8232" modified="2025-10-08" version="1">MSAPPAPSAPPSAAFSSGVASTPSQSGPVPSASTSPPHPSSQSAKDDTNASTGSGAAGAGDAGDAKPAAGATSSSSPVSGSNSGAPLAPKKAAGRDKDTYNQVMIERYLTHDGLHSAALQAAQVQMQKDFRNLHMYADDYRKLRTEYRQWFPSRHIYGEGYVGLGNGYTEVNGPPRILYPTQKMRPGKRTTPPLKYNRKDAAQQAEQHEELVPIRLDVEWDKVKLRDTFTWNLHDRLVPPELFTTQLMEDLGLKPPVSNQVYEQVFQQIQEQLGDFYPLVYSDEDALDPELPYSAYKNDEMRILVKLNITIGQHTLVDQFEWEINNPMNSPEEFAASMARDLSLSGEFTTAIAHCIREQTQLFTRGLYSVGHPFDGRPIEDPDLVSAFLPSPIPVVFRPQQQAKEYAPYLYELSEAELERNELTFSREQRRQKRSVNRRGGPILPDLKDRQRTIRTLIVSSVLPGAATDIDDSRLYKRAAHGPIGAGRRRGGRDGESDSDDSDDSSPDSPSMSQLAGTARTRGIRGAASAAQQRMANIGRSETPEAGTIHHHESRLGRRATRDPREDSVDDVQVPSRLVVTFKVNKDRLKKLLRDIKTRQTSGGSVPPPAAPSDAGSQTPSSSHQQLQPSAPGSQQQQPRSASNSMGPPPTTPSSKNALTPARPAVPHGHLGRLPAPPPPSSEADAPPAPPPPQWLLDALQRLRERSYPHDSFEGVMRYSVFNKDEQLVAHPGAGESLENYKFWYLPRIRCHDCPGKLYTPGPEMTVGNFEVHLKNRFHREKVDQRLAREAAAKGLPPPASSLPAGSASPSVPPATASTITAPQRPSPSAASVGSFNASDAAAKKSGEGAAAAGTSSGSASQTSTPGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC47</accession>
    <name>A0ABR3ZC47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxysterol-binding protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kes1</name>
        <name evidence="3" type="ORF">Sste5346_003729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF184">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="46878" checksum="F452E3774B67EC47" modified="2025-10-08" version="1">MDTSQQSPAAQASGSSWTSFVKSIASFNGDLSSLTAPPFIVSAKSLTEFSSYWAEHPALFSAPAHEPDPEKRAVLVLKWFLACLKQHYASRSEQYGNEKKPLNPFLGELFLGTWEDDVASPEAPKGSGTTELVSEQVSHHPPATAYSITNVPTGVHLEGYNAQKASFKSTIIIKQIGHAVLTVPVPSSDGKEAEPDKYLITLPGLHIEGLLFGSPFVELDGCSYITSSTGYTAKIDYSGKGWLSGKKNSVTAVLYPTGREKEVLYNASGQWTKSFSIHKGAAKHNSSSTLVTTYEPAQSPTLSLNVAPIEKQHPFESRRAWRNVAAAVAKGDLDTLSVEKTKIENAQREMRAKEKAEGRVWVCRYFSAVPEGEVDPVLSSLAANVGLSVNGDSDKTGGLWRFDRTKAEAAKKAVPPTNEEAAKIAQEFLGQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC89</accession>
    <name>A0ABR3ZC89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitogen-activated protein kinase adapter protein MST50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MTS50</name>
        <name evidence="5" type="ORF">Sste5346_003979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09533">
        <property type="entry name" value="SAM_Ste50-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051569">
        <property type="entry name" value="SHANK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24135:SF28">
        <property type="entry name" value="LD13733P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24135">
        <property type="entry name" value="SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="69"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="4">
        <location>
            <begin position="394"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="500" mass="54969" checksum="74AEB79314E1E087" modified="2025-10-08" version="1">MSFQQGTAYAESDADDEYERDIHDSSPIDATESELSPTETDIPSAEHTPTTYGYHSSADRLPETIITDWSAEECADFIATIGLQQYADGFIENEIVGEALVALLHDDLKQMGVNSVGHRLTILKSVYEVKKAQEVPIESDHYVPLTAETEAQATMATLKDIKNLVEQLRLRDERMSLFEQDYRRLTEDFRRLREDVLPALRLVKEQQPLPHVNSNGSSTAANNDQSYPFEAIISPPITTPQSGTHSINIKRQYSTRKMVPTGTTPKTTSPTHLQITHDRMIAEQTLDPANAAERAVLSSQHLAAANGNGQTASSPSYPSPNIPSPTSPPIAGTTLASRSYRSDQPTPSGRSTFAESDRDHMYNSSSRDKHSGTPRRMQTPAPDTPGSNAAVEIFKSFRVSMEDPCYKVLPAALRRYQINAPPDQYALYIVYGDQERCLALNEKPLILFKQLDKEGKKPMFMLRKTANAQMDGPTDVPGSAGLNAAARGASTGYDPPGGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCA2</accession>
    <name>A0ABR3ZCA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="170" mass="19134" checksum="CD9FA36B21058382" modified="2025-10-08" version="1">MAVLITVEPVPGYFTRRRVMSAVAALVIIIELINDLEGIVLANLQRWLHHLGVVITLTDGFAARVMARYRNLGSILRQLRPHNTAISRVVAAAAIILEKHSFTLTGDGHWENPFRYIIMGKYADDTAPRIEITPEDVEALADLNNTNQDVILYVHRAIIKDSDYYEREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCP1</accession>
    <name>A0ABR3ZCP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="119" mass="12970" checksum="8469AF7C92531358" modified="2025-10-08" version="1">MSTAPSGQPYRLLTVNNAPARAKLLIGRVTTNLADQYQIEHVGNCLSKDEVFEKVTELNPDIICCASMWTPEEAAEMHSIARSVKPEIKTHAIPQGLQVREGPDAIVAHLSEALPKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDN7</accession>
    <name>A0ABR3ZDN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003925</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF97">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="78"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="528" mass="58875" checksum="DFB8BE3EB1C7CC0A" modified="2025-10-08" version="1">MAAPEKTNTVLPIPSDQMSTQEGDHQMTGGVDNLPPPKTVTADQGHTDVALGVIVNETSVDLDPALRRRALRKIDTWVLPLLALTTMLQFLDKSTLNYAAIFGIVEDTNLRGSEYSWLASIFYFGYLVIQPVAANLLQKIPPAKCLAVTVFIWGFILFMHVVCTNWSGLMAVRFFLGMAEGVVTPAFMLISTAWYARRDQPLRMGIWFSFNGIAGIIGGILAYGLGHIQSSIDSWKWMYLVTGALSIIWSIALWFLLPDHQGKAWFLDEHEKMAAVEMVRSNHTGVHNSKFQKSQMVEAFCDPKVYILTLMALVWNIPNSIATFGSLVIENFSFTVLGTTLLGMPAGAVEFVLMIIITFVCLRVASLRIFCMITALTIALVGSIMVFALPYDNKNALLGGYYLLYAFPTGYILLLGMASANIAGHTKKVVANSLIMIGYSVGNIIGPQFFLTRQRPRYRLGIGSCLVSFAVLIALCIMLRFYLMWENKKRTAIREAADQQQQEDGQDHSQYDFRNLTDKENPLFVYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDQ0</accession>
    <name>A0ABR3ZDQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="159" mass="18246" checksum="80B5F0516B66F10D" modified="2025-10-08" version="1">MQQQHKQGHLLPPPPPPPQHNQQQQAPPQQLHTTAQGPYKCNVPGCTAAPFPTQYLLNSHANVHSSERPHYCPVRGCSRSEGGKGFKRKNEMIRHGLVHQSPGYVCPFCPDREHKYPRPDNLQRHVRVHHKDRNKDDPLLREVLAQRAEGPSRGRRRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE26</accession>
    <name>A0ABR3ZE26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27762" checksum="530CBB97FD14ECB7" modified="2025-10-08" version="1">MSYRASLKVYNGRFTDDSLIISILSPFSVYMLPAVAWAAYGYGCSIAFSASFSLSLSAIFGTAPYNFTTAQIGLTVLASFVGGSLGNILPGPILDWLVTYMARKNHGVYEPEFRNVLLVPAFVLGLGGFWGFGLSLHYKCHWMAPVFFYGLATFAGAIVSLVSNAYLLDCHRLAAQEGYAAVTFGRAVFSFIMTFVISDWIARDGILSVFFVVGALHGFACIFGLILYVYGKRIRLAVHKSPFIRRAIGTVKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEK3</accession>
    <name>A0ABR3ZEK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Spindle-pole body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003028</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="8">
        <location>
            <begin position="195"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="9">
        <location>
            <begin position="1294"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="710"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="982"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1044"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1162"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1432" mass="161661" checksum="2602CF7AF0A49E31" modified="2025-10-08" version="1">MVHPGLGGLDTPRTNAGDATYLERPPDFDVSQEMSFQSPTKDGNIFDQMRNGGKPNLRTPRGSSNNNGARAPFSNRQNLPEGIGGVEFTPLLKSATRNSARRGFRGKENGAAGAVPFSLGKIDEDDTTTPIPGAMDLSSFGVSRNMSYVDSTPLPHIDSSSIASTPIAIRPRGGGGGGDNNRDNGGPLQDGNQLSLREQENVIDRIEKENFGLKLKIHFLEEALRKAGPGFSDAALKENTELKVDKVTLQRELQRCKKLLISAEQNLENYRQEMLNMQDKMAQRQADEGLRAELERLRDELAAKDADIEELQRQVDEQNDKARDEIEDLEADLREKDRIITQKEDELEDLQVSMEARMEENRERIAELEEKANSSEKLDEAKETIDDLEADIRRLEQQIDDMKEKLDEAVTERKRAEEDLDELQEEMANKSVHTKGLSRQVEEKVARLQGEVDKSQRELEQLQEKHEEQLKEAEDLKLKLKESRQARDTAEREALAATSQLKEAHADLNMARDQKTLLQTRHDTLAAESAPLQRDVHRLEKAVAQLENDLDEERQHALEVEQDLGVQVKAEMERLNKHIIDLQTEISEKEHLYDIDSEKWDTDREHLEAERNRLQQTINRLRETEGALSGKEAQLQELMDSERMRHESEENVLRRQLESLQSQLDTRQGTLDGLRKELASVRDELRSSQLASQTAKNKCERLEDEVEALQRSRNRDAEQARQDKDLAQEERDSLRKQLATLRAGGANATSTAAAVTALQESAASTAQQHREQIDRMRTQITESASNVARITKEKQGLQDQLANINIELHSLRASLTETKVERDEIKEQLRRSQQHEGDTFRVDQERIDLRTAKMKLDSEVRRLRDENKSLADQCQTLETTLEEELEKAANEEERLGQEVRQLQSLRLRSSTTESQELQAARRTIRDLERRIEDFEVAAATAAVLPPSINTAGNDDTNTGELSMMRRDLSAARAKEREYLQREATHKEAVKTLRRQIADLERAAHEADMDRLMRSPEATVDVGSTTSPSSSAARKAEIVQLREQLLAAHQSVAEMKRTLREAERNAESSAASAEELEIRIGEVEEERAILEQALDEAQEAAAEAASTHEAALRRVQTKLERYRHERDELALALADVQNKAGSDSESVSSEMSREERSNLHAMLRKTQVEAEALEHDLRDHRTALDEAVRSEETLRAKLERARGERAAYRADAERLQRAVNDLQESASKTRAAMHYGTTTDAPNNTRELVLAAASVSQRNGNADTDALVRASEEQSIRHRKELRGLGMQIDWMQARWEREARLRCGAVLGKQLVSQDLEMRIACNKADLRMLQDILHQLGVKQPVLQSTSIEAASGKALVVKSASSARKTLRRAVLAVQFMVRIQQTAGTWAKHEATRQRLAAAAEGVRKAERMQQMRAAWRVQLATAASSRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEP7</accession>
    <name>A0ABR3ZEP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RCO3</name>
        <name evidence="11" type="ORF">Sste5346_003490</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="19"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="511"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="551"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="587"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="632" mass="67895" checksum="B48CEDD0959D2F7D" modified="2025-10-08" version="1">MGWRRPDNIAGSSAQAIMVGFFVATGGLLFGYDTGTINGILAMDSFLYQFAVGGSVERTPTSTPPPLPVSQQAIIIGMLSIGTVLGSLLAAPTGDYFGRRKSLIASVGVFVFGAIFQICSTNIPTLLVGRFFAGVGVGTISVLVPLYQSEMAPKWIRGTLVCAYQLFITIGLLAASIVNILTYKINGAAAYRIPMGLQLTWACVLSLGLLVLPETPRYLVKRGQKEAAALSLSRLRRLDITHPALLEELAEMIANHEYELALGPDTYRDAFFGSPHLGRRTLTGCILQILQQLTGVNFIMYYGTSFFRQAGIGNAFTVSLIISIVNSVSTIPGLFVVESWGRRNLLMIGAAGMGVSQLLIASFATAAPSDMAQTSMQILVIFVAIYIFFFAASWGPVAWVVTSEIYPLKVRAKSMSMSTAANWVLNFGIAYGSPFMAGEGKGSAQLGARVFFVWGSFCIVAIFFVYFMVYETSKISLEQIDEMYERVPKAWQSKSFEPSWSFQQMRDFGFSESGIPPEELSDDPNGSQTGNDSDDNSDVPPVYTPHAASGGATSTGMNTASISHNTPATPVAAYRQNNPRRPPPNTLTPTATARSDTISTSTSSTTAISSSSSSSDADNKMLASMAHVDLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGL9</accession>
    <name>A0ABR3ZGL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RasGAP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gap1</name>
        <name evidence="2" type="ORF">Sste5346_003127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="1">
        <location>
            <begin position="158"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="752" mass="86114" checksum="1A024109DD0517BA" modified="2025-10-08" version="1">MSSYDGTRSARQSKRISMSALYMSMSAQENDLEIEDDLAKAQKILRDLKAKISSQSKQNFVLEKDVRYLDSRIALLIQNRMALEEQNEVASRLEDANELQVGAFPNDDKTQKYGNLMFMLQSEPRHIAHLCRLVSMSEIDSLLQTVMFTIYGNQYESREEHLLLTMFQSVLTYQFDNTPEYSSLLRANTPVSRMMTTYTRRGPGQSFLKAVLADRINSLIELHDLDLEINPLKVYERMVEQIEEDTGSLPASLPKGITAEQAAENPQVQAIIEPRLTMLSEIANGFLTTIIDGLEEAPYGIRWICKQIRSLTKRKYPDANDQVICTLIGGFFFLRFINPAIVTPKSYMLIDGTPADRPRRTLTLIAKMLQNLANKPSYAKEPYMAKLQPFIHQNKDRVNKFMLDLCEVQDFYESLEMDNYVALSKKDLELSITLNEIYAMHGLLEKHQNELCKDNNSHLAIMMNELGGAPAQLPRKENRVINLPLFSRWEAALDDLTAALDITQEEVYFMEAKSIFVQIMRSIPNTSSVSRRPLRLERIADAAATSKNDVVMVRKGIRAMELLSQLQEMKVTDKSDGFAVLRDEVEQELQHLGSLKEGVLAETEKLSEVFSTITGHNTYLNGQLETYKSYLHNVRSQSEGTRRKPQKQQVLGPYKFTHQQLEKEGVIQKSNVPDNRRANIYFNFTSPLPGTFVISLHYKGRTRGLLELDLKLDDLLEMQKDNLDELDLEYVQFNVPKVLALLNKRFARKKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHL7</accession>
    <name>A0ABR3ZHL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome-interacting GTPase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RBG2</name>
        <name evidence="5" type="ORF">Sste5346_002513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="65"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="292"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="371" mass="41239" checksum="309938BD46E7C687" modified="2025-10-08" version="1">MVNITEKIKEIEEEMRKTQKNKATEYHLGLLKGKLARLRAQLLEPGPGSGGGPGAGFDVSKSGDARIALVGFPSVGKSTFLSKVTKTRSEVAAYAFTTLTAIPGVLEYGGAEIQLLDLPGIIEGAAEGKGRGRQVISAAKTSDLILMVLDATKKQEQRALLEAELEAVGIRLNCEPPNIYLKPKKAGGVKITFQAPPKNLDEKMIFNILREYKMLNAEVLVRDENATVDDFIDVIMKDHRKYIRCLYVYNKIDSVSLEFLDQLAREPYTAVMSCELDLGIQAVVERCWQELRLIRIYTKRKGTDPNFTEALIVRSNSTIEDVCDRIHRTLKETFKYALVWGASARHVPQRVGLGHLVSDEDVVYIVSGWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIN7</accession>
    <name>A0ABR3ZIN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase (Ubiquinone) 1 beta subcomplex 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008699">
        <property type="entry name" value="NDUFB8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05821">
        <property type="entry name" value="NDUF_B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18969" checksum="3D0CE18A56DBF60B" modified="2025-10-08" version="1">MRAAALAAARRSLVPLQQQRTFIPESINGRRVIDEKYPDTPHLTEAEDPLQNGGFVMPAPVKRQFRDPHGDWWDKQERRNYGEPVHEDYDQLGMFTPYEYTWTTTGKGLAQIGMFIAAFLTVVYTVKQTYPDRVTVPRTFEGGLERELGGPGAVRARSPEDEEAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKC2</accession>
    <name>A0ABR3ZKC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="250" mass="27033" checksum="AC69E16F1D68771B" modified="2025-10-08" version="1">MADFNARYVATNNRYGAPDYDETFIDGLRAELVKNAVEAEAIVDAVLASLAIGAHRADVVAKLFEKAIKPVAIDQVAVGRTMDTFRAVLMIVWPFVGIPWCVPAALGIVDVLKRHNIELPDTTARPFINESDRDIGHQLLKRTYQNVNNAEVQDMLRTFFPDFANLTWAVVFGYSLAGTTATGVFTESQTQLILATATVASGALRQARSHLRGAVGLGISVQAAAAVSRSAVKFNAWNGVDITGVTELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM9</accession>
    <name>A0ABR3ZKM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="36518" checksum="FC6A0346A82D584E" modified="2025-10-08" version="1">MSSTIDRPDLTQLQAESAAATATSDQLATQFHDNMVGKSVLITGVSPSGLGAEAARVVAAHSPKLLILASRSPAAIEEVIANLKADASFDATKTAIEPLKLDLASQESVRAAVASLTTSHPDLVLDVIINNAGIMMLPSYEGVPDASGKNIEKQFGTNHIGHFLLTNLLAPALLRSKAKGGARVVSVASRGYLGSPVKALDDASLLDDTEANRKAYDSFAAYAQSKTANLLFTVGLSQKLAGKGVVAYSVDPGAVGTTSLSRSVPMEVQKAMGWRLEDGSLNPVAPFISAAQSVASYIKAAYDPELLSQSGATITSAAVDTGILDYAKDPELAAKLWTLSEKLVGEKFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL29</accession>
    <name>A0ABR3ZL29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RHO4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rho4</name>
        <name evidence="5" type="ORF">Sste5346_001988</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04132">
        <property type="entry name" value="Rho4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="257"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="304" mass="33445" checksum="4F015F806658A198" modified="2025-10-08" version="1">MSSQYRNSYYQQSSHDNTYEYGIQRRPTTDRLESRPARTSDSNTISTTSSSSGRESSATAMTNMTEPPTYSKKIVVVGDGGCGKTCLLISYSQGYFPEKYVPTVFENYITYPTHPPSGKTVELALWDTAGQEEYDRLRPLSYPETDLIFVCFAIDCPNSLENVMDKWYPEVLHFCPYTPLVLVGLKSDLRFKKTCIDMLKTQGLTPVTTEQGLAVAKKMGAGYMECSSKEMKGVDEIFEQALLTVVANDRRNLEAQAAANSSGKNAAAGNSTTTGSGGVTFSSGNGNMPIGVPLKRKKRRCIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLM4</accession>
    <name>A0ABR3ZLM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002174</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044989062" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="40"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="577" mass="61205" checksum="492A5855EADD77B9" modified="2025-10-08" version="1">MTGFSARLALAALAVVGTVSAAPAPNPVIKERATSVTMVLPLGTVIGTSSNGVESYNSIPYAQSPAGVNRLKPPVKLTTSYGVLDGTGPAAACPQFVESTSGSFLAEVLGTLADSPFIQTVTGQTEDCLTIDVYRPAGTKTTDNLPVLFWIFGGGFELGWTSMYDGAGLVANSITLGKPMVFVAVNYRVGGFGFLPGAEVLAAGASNLGLLDQRLGLEWTADNIGYFGGDSSKVTIWGESAGAISVLDQMILYNGNITYNGKALFRGAIMDSGSIVPADPVDCPKGQAVYNQVVSKAGCSGSTDTLACLRAAPYTTFLNAVNSVPGILSYSSVALSYLPRPDGVVLADSPDVLVTSNKYAAVPMIIGDQEDEGTLFSLFQSNITNTNQLVTYLSDYFFHDATTAQMQALVATYPDNASSGSPFNTLILNEIYPEFKRLAAILGDLVFTLTRRAFLTATYKLNPSVPSWSYLASYDYGTPILGTFHGSDLLQVFYGILPNAASKNIHSYYFNFLYNQDPNNAAGGTSVTASKVSLNWPQWGVGNQLVQFWALTSNLITDNFRSSSFSWIQANIASLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMQ4</accession>
    <name>A0ABR3ZMQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="167" mass="17922" checksum="3FABD41A7E47D64D" modified="2025-10-08" version="1">MAQKAKKDRAKSNAATLNNLHLGSLIVNVAFLLFYLGFRSRSLVTYVVMSLPSFLCQFMLERTGRPHYDAQTGALRTSGEDLAAAGLTEYMFDVVWVTWGVSVLVILFGNKLWFLWAIVPAYGAYKGYGLLGSARQMAAMGGLGGGGGGDAGAGAAPPPNRRQRRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN75</accession>
    <name>A0ABR3ZN75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="114" mass="13102" checksum="22353B7A2B0A77CA" modified="2025-10-08" version="1">MFRKTTDFLDFLNDAALYLAVSDADPPTYPKHVWSPAGGWYAQPNNWKRNTAIAGLAVFGITAIVWKIDSELEYRHKMPEPGRFFPSRYWSRQIIEYEKEQKAKAEAAGTTESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNF6</accession>
    <name>A0ABR3ZNF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_001695</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="13">
        <location>
            <begin position="37"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="14">
        <location>
            <begin position="309"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="45492" checksum="99528F86469949D7" modified="2025-10-08" version="1">MTLQRIRPSVVRNLRTAAAARQFSVQSALRRETQDAYILSASRTPTAKFNGSFVTLPAPKLGAVAIKSAVEKSGVPVEKITNVYFGNVLQGNVGQSPARQAAIFAGLPTSTEATTVNKVCASGLKAVALAAQDIELGLSEVQVAGGMESMSQAPYYIPRSSSLPAFGNVTLEDSLIKDGLTDAYDHHHMGICAETTAKKHSITREDQDNYAISSYQRAKAAWDAKAFADEIAPVTITDKRKKKETIIDTDEGYLDVKIEKVPQLKPAFLRDGTGTVTAANASSLNDGASALVLGSAAIAREYANGGKSRVLAKICGYADAAVEPIDFPVAPAKAVPIALKRAGITQQDVAVWEFNEAFAAVIKANEKILNLSSEARVNPLGGAISLGHALGSSGSRILVTLLHQLKPGEYGVAAICNGGGAATAMVVQRVESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNW3</accession>
    <name>A0ABR3ZNW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">vps26</name>
        <name evidence="3" type="ORF">Sste5346_001562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="325" mass="37562" checksum="17EDD73C076FA0B7" modified="2025-10-08" version="1">MSYFFSTPVDIDVVLENSDDRSMVDVRLEKNRREKAPLYMDGESVKGAVTVRPKDGKRLEHTGIKVQFIGTIEMFFDRGNHYEFLSLVQELAAPGELQHPQTFDFNFKNVEKQYESYNGINVKLRYFVRVTVSRRMADVIREKDIWVYSYRIPPEMNSPIKMDVGIEDCLHIEFEYSKSKYHLKDVIVGRIYFLLVRLKIKHMELSIIRRETTGAAPNQYNESETLVRFEIMDGSPSRGETIPIRLFLGGFDLTPTFRDVNKKFSTRYYLSLVLIDEDARRYFKQSEIILYRQAPEIAEAAAAAPSAIHAPPPENKATMALPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP67</accession>
    <name>A0ABR3ZP67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 10">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PGI1</name>
        <name evidence="11" type="ORF">Sste5346_001481</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="562" mass="61619" checksum="146B9E3E3464B57B" modified="2025-10-08" version="1">MVQASSLPAWAELQKHRNTVGESFVLKDAFAKDPKRFDKFTRVFKLPADIASGGEETDILFDFSKNFLTEETQALLLKLASEAKVEDKRESMFKGEKINFTEDRAVYHTALRNVGPEPWTMTVDGVDVVKTPGGVNDVLEHMKEFSEEVRSGSWKGFSGKKLTNIVNVGIGGSDLGPVMVTEALKHYGASDMTLHFVSNIDGTHMAEALAASDPETTLFLIASKTFTTAETTTNANTAKSWFLEKTGGKGDIAKHFVALSTNEAEVTKFGIDKKNMFGFESWVGGRYSVWSAIGLSVALYVGYDNFHKFLAGAHEMDKHFRETALENNIPLLAGVLSVWYADFYNAQTHLVAPFDQYLHRFPAYLQQLSMESNGKTVTSDGSSAKYTTGSILFGEPCTNAQHSFFQLVHQGTKLIPTDFILAAQSHNPLSDNVHQKMLASNYLAQAEALMVGKTADQVRAEGGVSEELVPHKVFLGNRPTTSILVGGHIGPAELGALIAYYEHVTFVEGAIWDINSFDQWGVELGKVLAKKILKEIDEEGNGADHDSSTGGLLAAFKKYSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP77</accession>
    <name>A0ABR3ZP77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">H(+)-transporting V1 sector ATPase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VMA8</name>
        <name evidence="5" type="ORF">Sste5346_001250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="210"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="260" mass="28945" checksum="BECE17DCA5602917" modified="2025-10-08" version="1">MSGAADREAVFPTRQSLGIMKAKLKGAETGHSLLKRKSEALTKRFREITRRIDEAKRKMGRVMQIAAFSLAEVTYAVGGDIGYQVQESARSARFRIRAKQENVSGVLLPTFESYQTEGNNDFAMTGLGKGGQQVQRSRDTYARAVEALVELASLQTAFVILDEVIKVVNRRVNAIEHVIIPRTENTIKYINSELDELDREEFYRLKKVAGKKQRDTAAEDAELKARKEALEASRSSAKAGNEDESEPSDLLADGDDDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPQ6</accession>
    <name>A0ABR3ZPQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL20B</name>
        <name evidence="6" type="ORF">Sste5346_001118</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="174" mass="20381" checksum="0E142C4AC3F35B6A" modified="2025-10-08" version="1">MGRLQEYQVIGRHLPTETNPSPALYRMRIFAPNTVVAKSRYWYFLRGLKKVKKATGEIVAVNEISEKHPLKVKNFGIWLRYDSRSGTHNMYKEYRELSRTAAVEALYSDMAARHRARFRSIHILRVVEIEKNEDVKRPYIKQLITKNLSFPLPHRVPKIPTKKIFSAKRPATFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQH4</accession>
    <name>A0ABR3ZQH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="837" mass="89485" checksum="5E6BEC574EBD924D" modified="2025-10-08" version="1">MGPPTKESVLQAMRSDLGMTRVDDLELENGQRGHTVRTGKASAVLAKAIAPPRKILPVANKWKTAIESGAFDDDDAEAVKGLDRIGGGRLHAVGATPAIPAQYFSQQRMFPPGLPPPGFGRSPNTFQPSRPPPNMMPPSVPFNGFGQQAARFPPGPPPGLSQNRAPVSFEMPPMAAPASMGFGNIDNDVARRLAENSPMPQRTVQVPANTARRPPPPVPLASEVAKTPRPQDPIPAEFAYTVNIRVADRLAKGEGAIYLVAPSDSDPGTFHIYLEGSKYIEYPIVSMFNYMTTSTDLCPQFKEADGASITTTRLVFGSQDRIATFMKELRALKARKPDPVPKVAPAAAPEKQPADIPVSMPAFLKKPAAPKTSDKESAPPATPANKPAMDILSSPPPVPRPAGKDQDTYEIKSTFNILKDSANAISAPKSRPAVLVLDYGNDDYGKACDLVDLSHAVDANGSRPTTQSAMSSTYAMDLGSLQESHFVTPADAEPHVFVDSVQASVAPSEVVEVEVPDTEPVAELAPAPAVAAVAKPSAEPPIKSPTEHTTEPATSMKATPVTHNNEFGADDPVESMERLQASLIEILPKFEAMSRILDSVEEKKREATAKSVFTNLRSSLGDTRDTQLSSAEQLLRALLVKLSQEKPTATKVADTVCHLRYARDEITRLREQAAPPPEVLFKLDFLPLASKPRAPRKTPLASKPVPPKKAPVTPKHTPTSSCTNNKPQSTLSPTAKPFQPSPPHKPRPTQLATHVASPGTAPAVQSVTRPLASPSGVPNSSISTNLESLTERMSRLTLPDSNAKTPTKGLQGSRWATATKSIVRTENANRFKGIIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQL8</accession>
    <name>A0ABR3ZQL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="7">1.1.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2</text>
            <dbReference type="Rhea" id="RHEA:21252"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16782"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the L2HGDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.2" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF4">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="50"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="47477" checksum="86C977CE718C5C2A" modified="2025-10-08" version="1">MTSGSFKMLNSSRQRLFPAARRATVQTSVTSTSLRLFSVSAHRRADFTHAVIGGGVVGLAVARALAERAASVAPSSSSSSVLLLERHNTVGTETSARNSEVIHAGLYYGPDSLKTQLCIRGRQLLYGFCEEYGVAHRRTGKWIVAQTPGQREALEKIYAFGQNYHDRDAIPLQWVDTDEAKQREPAVRAEAGVLESLATGIIDSHGLMQTLLGLFEQAGGVLAPGSPVTKITPLGDSGTGSGGWQLCVKPTDADADVEETVVTAETIVNAAGLGAAAIHNMITQGHDSSHLERQEPMQLYYAKGNYFSYAHSQPRVSTLVYPAPEPGLAGLGTHLTLDLAGRIRFGPDVEWVTDPTDLAVNADQLPQAIEAIKTYLPGVDPTALQPDYAGMRPKLVKAGQGAADFVVRNEPGYQGWVNLLGIESPGLTSSLAIGEMVEKLVYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR53</accession>
    <name>A0ABR3ZR53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate--tRNA ligase msd1</fullName>
            <ecNumber evidence="8">6.1.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MSD1</name>
        <name evidence="8" type="ORF">Sste5346_000456</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="entry name" value="GAD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="212"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="732" mass="80631" checksum="EB93C216B387C078" modified="2025-10-08" version="1">MTTAAVSRRGVQTLMASRSQVCRRSMRAVPRQISCRQFSLSSKRLAKEGSKKSKVSPEDKAKLWDEYKQSFHFTPASPPDSLRVGGTVTVHGFLGKRRDISAKAAFVDVVHPGQSRPVQVRSAWEVEGSPEHELHLQLKAANSYSPVAVTGLVEEAPGEGTLEEKGNALLRLGSIQVLNAFPRDIIVSKGVQFPATARHLQMRFSEALQRRLAFRSDVASWSRKQLTSAGFREFETPVLFKSTPEGAREFIVPTRRRGFAYALPQSPQQFKQILMASGVAGGYFQFARCFRDEDLRADRQPEFTQLDLEMSFATGEDVMQAVERYTKELFAYLGETYRLAKNTAGDDNKTIPIPIEALSKGKGTLSTRPYATISDEPFQRMVYDEAMAKYGSDKPDLRIPGEIHRVDHILPSSFTSMITSLEDPVVDAWRLRLDGSPSESRKFVQRLFDSLPPAIGKNPDGMPAVMIYDSSKPLCGLAPLGHEAFGELTDADEHPELANLSDFEDGDVLLLQARKREPFFSGGSTALGLLRLEAYRAAIEEELLPYDDTFRFLWVVGFPMFTPTEADAADPGQGGHAGFSATHHPFTAPLTEQDFELLTTDPLRAKADHYDLVVNGVELGGGSRRIHVAAVQEAVMRDILKMDDAGVAQFGHLLEALRAGCPPHAGFALGFDRLVAVLSGTGSVRDVIAFPKSMKGEDQSVKSPGRLTPAQLETYHLALRSAKTSQGDDTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRH2</accession>
    <name>A0ABR3ZRH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF200">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="80"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="646" mass="69441" checksum="8CC4BEFFDEDD05D4" modified="2025-10-08" version="1">MAFEMEGRPEPAAMRAADISELAPADNKNVDEITSAPANNDTDAMSLKKGVVAEAQLGDVGAQRIEIIQKIWGKHGKILLYSVIGLAMVIYELDNTTFATYYVYALSDFQKVSSSSALAVATDLSFSLTKPIWAKMSDIFGRGEMYPVATLFVVIGYILAASANGFSAFAAGTILRAVGLTGINTLNTIIIADTTTARQRGFGVNFQFFPYLILPWVAAEIISSVVSPGGVGWKWGVGIIGIIFPFAMIPIIAVTFIFARRAKKIEASLTEGAIAGNSTAIDDEAVATVAAAGQVAAKPKVTPYSLASNIDLGGLLIMILSLAFILIPLSLAALQTKGYKTPWVIALIVVGGLGLLIAFPFYENYVAVHPIFPLRYVKHRAIGIAFLLYFTDYMAAAASHGYLYNWAIIAQNLTVVQATDLSYINGVFTFFSGMAFGFIMWKTRSFKWWLLLGLIIRIIGYGVMFRIRTQHPSLGELIVVQILQGLGDGIVQTGGYIAATINVPHKETAQAVALIVTIGMLGSSVGSAISGAIYTSTFPNELRKYLGDLATPELISNIINSIDTDIPAWGTPMRIGISNAYNQVTSYFFIAAMVIIAPSFILVYYLPNQKLNDNQNLLEDNGMLAAQQAAADLHPAAQPSTAETKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRT4</accession>
    <name>A0ABR3ZRT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="5 16">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">SDH2</name>
        <name evidence="20" type="ORF">Sste5346_000763</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="16">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="16">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="16">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Mitochondrion inner membrane</location>
            <topology evidence="1 16">Peripheral membrane protein</topology>
            <orientation evidence="1 16">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="5 16"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="14 16" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7 16" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="13 16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="18">
        <location>
            <begin position="77"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="19">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1902852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="293" mass="33075" checksum="C364E4BB0953ADC0" modified="2025-10-08" version="1">MAALRSSTMRLLASASSRPSMAARPMASAFNISSSSASSSQSSSRRSMATTSDAPVEAAPKLKKFQIYRWSPDTPSEKPRMDTFTLDLNKTGPMMLDALIRIKNEQDPTLTFRRSCREGICGSCAMNINGVNTLACLCRIPTDTTEAKIYPLPHTYVVKDLVPDLTQLYKQYKSIKPYLQRDTPAPDGREYRQSKEDRKKLDGLYECILCFCCSTSCPSYWWNSEEYLGPAVLLQSYRWLADSRDEKKAERKQAFENSMSLYRCHTILNCTRTCPKGLNPGRAIAEIKKEMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU28</accession>
    <name>A0ABR3ZU28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439152" evidence="2">
        <location>
            <begin position="20"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="702"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="757" mass="72215" checksum="0462C6D48415052F" modified="2025-10-08" version="1">MIFNNPIGWAALAASLCQAGPVAVAPALPPAHLARGNDLVARNALDKSVEVARGLQTRTAASYDLSHSWNNEMLFDGTYPNGLGGMVTMAVQCNTCYTKGSVSASLTDDTLVDPTLRLDFTGVEAYVDLAVQVSESAVYTINLFTSNTPIGMGVSGLSVGVVFAVDLVFSLSEKIDIDAGGFQVTLADGAYVEASLMQGTVTKSFFDGITAQSLPVSVKSGTATFKADLRVRTQCGAEGTSLVGIGAGLEVGVYANIIEFVSILETTEACGLQSREYWDCNVGAYALADVQVDYKTFGAVPTISTTLLSAPTATQCWGSIASAVTSALGGGGGAKYGGSTTATFVSSASSSKETGSYGSGKGSGSGSYSGSGSGSGSGSGSGSYSGSGSGSGSGSYSGSGSGSGSGSGSGSYSGGSGSSGSGSGSGSGSYSGGSGSSGSGSGKGSGSGSGSYSGGSGSSGSGSGKGSGSGSGSGYDNNKSTAKYSASASTSGSAAASASSPAVSSVHSSSPASSSPAVVSSSSSIPVVVSSSSAAAVSSSPSSSAAGVSSTPSAAAVSSTPANTISPPPTTSSAALSSSPSVTAATSASVGGGAVTSTVLSTTTYTITSCAASVVNCPASYQTSYVVTKTYTNKGHGKGSNTGSAAVVTTTNGAHLALTPTTTNIIVLVPCTSPIVETFTPPTALPTSGKGNGGSGSGSSGSSGSSGNSTLSGTFSPTASKTGSASGVVVTAGAVSGSIVSSSLAAVVGVFAAALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZVI4</accession>
    <name>A0ABR3ZVI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein ECM13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037738">
        <property type="entry name" value="Ecm13-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36826">
        <property type="entry name" value="PROTEIN ECM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36826:SF1">
        <property type="entry name" value="PROTEIN ECM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35106" checksum="298964624605F769" modified="2025-10-08" version="1">MSTTTITYSSTKTSSFAPSSFSAPQRKTMSITQTYFLAHKARAKLSSQAARPDHNLRLLVGHANLLDTLMLELADAEREQESWFNQSVRGANKAQQSQQSAPKADRHVQWADTVIEEPEEEWHADNDDDSDASSDASSDYSESDDDEFDDDFEQQSPASSIDDEDILMADAAPLRRVNSNKAIIETVDEDEYSTEEEEDEEDDEATHAHLTLTRSPSHSASSLSSSPSSSLSHISSPPELVIEEDSDISSEDDESSMPPSPPAVALQSFDKKTAAATTTAIKALASPQEDDHDAFDDDSTAHYYLPPRNPARLITALSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFW6</accession>
    <name>A0ABR3YFW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flavin-binding monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010421</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000144">
        <property type="protein sequence ID" value="KAL1887132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="67142" checksum="646B397D7969705C" modified="2025-10-08" version="1">MVYPNQPHYTDFEVPILNRPIDDPGRTLRVVCVGGGIAGITTAIRFRQHLGNQITFQIYEKNDDVGGVWLENRYPGVACDVPAPCFAFLFEDNVDWTSYYAGGVEIYDYIKHVATKYQVQRDIKFGHVVQGAVWHEDEGRWHLTVLDKATGTKLDDTADILILGWGQLNHWAFPDVPGLHSFQGPYMHSAAYDATFDATDKTVALVGGGSTGVQILPQLQPVARKVQQYMRSQNWIAPVGFGSEELEKRGALAQGNFDYSDDEKKAWKDDPSSYHSYRRHVEERMMALMTEEGFKYGTPEQQAMETQFREHMKTALRTRPDILKTLLPDFPPGCRRLVPGPGYLDAVVKDNVEWIPQGIDRVVENGIVTTDGQLHQCDAIIWATGFITDFDSRFPMVGRDGITWNQVCRPEPEAYLGVLTDKMPNCFLYLGPNAAPGAGNAYLCVELECAYAIKCIRKMLLEKIKSMCVKTERVKQYTAHAASYNKATIFGQNCRCWFKPKKDGGRNIAYYPGNSLSQMIAMESPRWEDFDYTYCDELNGNPMGWLASGFTRADYDGSSRTTYLDPANIDYPPVPTVNGNREQENGTKCNASTMSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGR5</accession>
    <name>A0ABR3YGR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nitronate monooxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000121">
        <property type="protein sequence ID" value="KAL1887417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="31770" checksum="BD43CDC2E978E507" modified="2025-10-08" version="1">MSGMAMSDLAVAVTRAGGLGFIGYNDFPVLEEQLQQSRELLLQDKGTTVTLAAAVAVDVLPLGVGIIVAFAGSTLAFSPLFAKHKPAVVWLSFGEATDFKTWTDAIRAASPQTKVWIQVGSVRAALEAAQACHPDALVLQGSDAGGHGHARGASIVALIPEVADALNDDHGGHGGLSDISLIATGGIMDGRGVAAALALGASGVVMGTRFLAAEEIKVSEGYRNEILSASDGGEATVRSHIFDQMGRYQWSALYDGRSLRNTWYDDWQRGISVEEIRSKRDLKVDGSRSGDGDANFRDTNTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHY6</accession>
    <name>A0ABR3YHY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF57">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="800"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="826"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="837"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="902" mass="99344" checksum="A0463343115DEC67" modified="2025-10-08" version="1">MASAPTDPATSAASTSAPQTAPSAQSAQTPSPARTSGTSPANRVQPRRAVPKRVVERSCIVCHRRKVRCDKTMPCANCVRSGVLCCYPSNKRAPRQPKTTIADIASRLVQLERTIVAVAGGDNGGDGHTDGGVDDNGYESDTPAPVQTHTQPRTNSNAHSSLGAALERRAANRAAPTSISTALHTNHGDETRSSGTPVGGAGEDDTSPSRDGTQSENGAAAQEILLQNAYASRYINELLLSKILEEEEEFRSALALPKEAETENDENVGHNASETAAPAITLFGMVTNSRHVPRPPSSRNVNMALHPPKRQAMQLWHEYLHSVEPMNKVLHVPTAEVGVFTAIHSPEKTEPAFESLLFSIYYATVTAYQPEEYRAAFGEDKAVALDRYRAGMERALVQARFLESPSLPTLQALTLFLRTSRAHSPGQSIWILYGMVLRLAQSIGLHRDGANFNLSPFESEIRRRVWGHMIKQDDRAAEDHGIDISLTDTDVDCQEASNLNDREIHPDMEVLPTPQMRWTEMTLPVCIRRLGNTMAYMMRLFTEMKASQQSGRVAARPSADLPLTEERRQDIMGARNAYVEDLMRQCNMVVPVQRATWKMVRLIQLKTDFVTRLQLAALLAANMRSEAERHRAIANEDHLVLACEVIELNVDILEDELIQDYRWTAEIYPQYHTLLYVLWHLCVQPIPITRPALRERAWAVAEGMYAMEDARQRRQNVRGRNSKWAVLMALREKALRVQSAMDVKGGAAGVPVPCPPVPAKVDGEQDVHMDDGESTKPATVNPVGTVPAYNAVLPTQAIPSEQPTQPVQPVDNAPPAVTSVRGPTTGLVNGQPSGFVQQQQQPQLPQQQPQQQPEFAEADMTEFLGDSALGLGLGMDMDWVRGFMDWNAVADDFRMRTYDAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI00</accession>
    <name>A0ABR3YI00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HTB1</name>
        <name evidence="13" type="ORF">Sste5346_010468</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000155">
        <property type="protein sequence ID" value="KAL1887044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="30"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="137" mass="14857" checksum="5AC738100B1D6545" modified="2025-10-08" version="1">MPPKAADKKPASKAPATASKAPEKKDAGKKTAASGDKKKRTKARKETYSSYIYRVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSTSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YID8</accession>
    <name>A0ABR3YID8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Agmatinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009913</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF26">
        <property type="entry name" value="GUANIDINO ACID HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045752840" description="Agmatinase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41342" checksum="56EDF9A54368B876" modified="2025-10-08" version="1">MRPTLLPFLLPSLAAATVNVGPDYEHHIEDLDVDLPFSQPVTFAHLEWQRCLAASHDKPLDIALLGFPYDTSTSYRPGARFGPRGIRAGSAREKKGRSYNTVWGVDPYEQGLEIIDCGDIPITPFDAAHAFKQMEQGYRQVLYHPTSDATEWKHPRIISMGGDHSIVLPILRSLKTVYGPISVIHLDSHLDTWDPYEGYTGIRSNQSALTHGTFFWHASREGCIAKGSSVHGGLRTKLFSPKDYEIDRDVVGFTIIEAHEIDDIGIEGVVRKTLDAVKDTPTYLSIDIDVLDPSIAPATGTPESGGWTMRELKRYIKGLEGVNLVGADVVEVSPPYDTIAEVTSIAAADLIVDILAAMVKGKDKAVVKKVRGKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIG9</accession>
    <name>A0ABR3YIG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010129</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="141" mass="16248" checksum="FCDA70FAF14590E2" modified="2025-10-08" version="1">MVKARLYTFSQETKDQLRKFRLGTSRARDPQAVIYLIDRATKEIRQDEEKTVYKSLDEIADDLPENSPRFVLLSYPMNLPSGRLSCPYVLLYYLPITCNSELRMLYAGAKELMRNTSEVGKVLDVESTDDFEELPERLGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YII6</accession>
    <name>A0ABR3YII6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dATP/dGTP diphosphohydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000133">
        <property type="protein sequence ID" value="KAL1887239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21594" checksum="B832181E003A021F" modified="2025-10-08" version="1">MGVRISDTGPSPVLSNLGDPDKDEVRIWRNQNGYLARCFEAGITDWDHYAMKALRAGLEGQEEGKELSTVSLECEILAATEWLIHASRKLHRWAEENDEDAANGVYDYSDGLPGGPLFSGRPGLSVARWNFWKERLDELSRKRPKKEPETTGSEVKGDLSTYELFSQEVYDAIENALKRMREVDDTKSNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIN4</accession>
    <name>A0ABR3YIN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009746</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044972910" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="49"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="611" mass="64456" checksum="67F6F6F7BD225B36" modified="2025-10-08" version="1">MARLLYSTALALAGLVSLACAVPATSPDTGFLGLPSFPTPPSQGSDPLTVNLGYGVYQGTHNATTNLNVWKGIGYAAPPVGSLRWQLPHVPKTNKTVVVADTYGPTCPVAPPSVPGTPFSPGDEDCLYLNVFAPSIISTTAKKPAAKLPVLVYIHGGGYGGGDNRYDMTGFINDNNNEFVVVAIQYRLGAFGWLSSADVHKNGVVNAGLLDQVQALLWVQNYIGLFGGDPNRVTISGESAGAGSVMYHAIGYGGNTPVTLFRNGIAASPYLVPQYNYDAAVPTQRYHDFATAAGCGTAKDIFACLVAADTWALQYASSNVSVEQTAFATWAFVPVTDGVYVCQRPSVQLATGPTNGVHLLVGNNADEGALFVPGGLSTQDALVSWIHSSFPGLSDTNVTALLAAYKPTPGYNASNGLLFETNGISPPTANDISQAGAGTQQLAYNIYAESTFVCPAYWLTGAFTPASGNKKSAFQYQYSVPFAFHTSDMAAYFGPATANQGPDFVVAFRQIWGGLVVRDDPSIVSTPSVTLSSPLPAFAFPSWTPTSHRLVVLNETGGVPVEVPEFWGGVSLQYNDPGLQNHFTIANATSWEGGREARCNFWKSVAPFLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT8</accession>
    <name>A0ABR3YIT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000097">
        <property type="protein sequence ID" value="KAL1888233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046619231" evidence="2">
        <location>
            <begin position="30"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="745" mass="82222" checksum="27C5F59230F66613" modified="2025-10-08" version="1">MVAVRLRKAARLLTLLAITFASLSNTANAAVRIPSNDEQLPIGDTIPHVDISSPQRYTPPLNFSSSAPHLFASAYGLLQQWANTVFPNGHAMVAATIPAYTLMYHGLRAEEANPDPDTLSPPSPEWLAFDLEMAYGIMGSARRSWLLTYQTTRPVRVLYVDGESAALMGLGQLDSQMLLLYGNVTGPSHDDRKGFGGLTDEYDRARGMCDWLERQGLRGRGWGYEGIVRMNAGFELIWCDFMSDSLRLLSRLNVTAPLDPVVVEEEEEEEVTDDEAKAAEQSYYTLPPVPTRSDRAIEPTNPPAPPNWRGGGGGRYGPGFPGDDDSAEKGEEPFLTSQGWGWFESATWHYGASRSGPGAGETRVQVDNCGILSYYAPRFEGGTLAQSRAEDEQKRLNLTAEGFWSSPCSSDANRTIALRQLGRRRRFHHLGNASVEDALLMRRSSEEALARTLSIHPQGGDVSSSACSGASWTLILSEIVQRMARHLKTVEAILLDGPSDTNQKNTTETRSWLHRLRSQNHMFMVGYLEYPTNKADTSAWQPGTVLFNRTLSLCRYRYTRLFAAGDERGQLPPEEDDLRWAIEETYGTLCAELLGIGFDVERAWAEKYLAKQEERDEDSLAMSTGYWLDQLTELIAWLGWENEWIGCDRVCGWNERCFIPMWPLMSSQWGRGGGPGGHPGGGEGGGPGGRPGGPGHRPPNNGSHGGGGRRSPPGFGFPRSPAMMGDDTDLWEPKCVEAWYIMGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ91</accession>
    <name>A0ABR3YJ91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycoside hydrolase family 94 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009591</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="entry name" value="Glycoside hydrolase, family 65, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="GH65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH94_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052047">
        <property type="entry name" value="GH94_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94_b-supersand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37469:SF2">
        <property type="entry name" value="CELLOBIONIC ACID PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37469">
        <property type="entry name" value="CELLOBIONIC ACID PHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="GH94_b-supersand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase 94 supersandwich" evidence="3">
        <location>
            <begin position="75"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase 94 catalytic" evidence="4">
        <location>
            <begin position="322"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="818" mass="92361" checksum="6E4799980B8B573A" modified="2025-10-08" version="1">MPFDVRRLVGPTSSGDRYDLTSPTAMPKAAGFLWNNKMMIQATCRGYATAQFMQPEPAKYSHAPNLEAKTFMQPEQSYYADHPGRFVYVQDLDSNELFSAPYEPVRKPLDKYVFSVGKSDLQWICELDDLKVEMTLSLPTNDVAELWTIRVSNMAPRKRRVAITPYFVIGCMSWMNQSADYRKDLNGIVASSITPYQKVDDYFKHKSLRLKDKTYFLCETAPDSWETVQEIFHGEGGIHAPSALFDNDKLGCNDARYETPAAVVQYRAELDEGEDREYRFIFGPAFDDTEIKSIRSKYLSRDGFARAARDYSQYIELGRGCLQVQTPDKELDNFINNWLPRQVYYHGGVNRLTTDPQTRNYLQDNMGMAYIRPDSLRVAFLKALSQQEANGSMPDGILLTEGAELKYINQVPHTDHCVWLPIALDSYLSETGDFSILDVPVKSDGDGKTMNVFERVSSAMRWLLSSRDERGLSYIAQGDWCDPMNMVGYKGKGVSGWLTLATGYALRLFAEVCDRRAGNADCMIGATKNEEAAKIAGELAIQFREGCKEVNNAANKHLWDGDWFARGITDNNVVFGIKDDKEGRIWLNPQTWAILSGAASPEQCDKILPEVDSQLGTPYGVTMFAPPFTAMREDVGRVTQKFAGSAENGAVYNHAAVFYAHALYTMGGRQVDRAYTVLRQMLPGPSDEDYKRRGQLPVYIPNYYRGAYHLYPRTAGRSSQLFNTGTVSWVYRCFVEGLCGLRGVPRGLRIAPQLPSKWNAITVTREFRGATFKVDIRRSRDVKTTRVKIAGRPDFLPEPIITDIEVGRTYNLTVLVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK15</accession>
    <name>A0ABR3YK15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Short chain dehydrogenase reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Putative oxidoreductase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32924" checksum="01FA46460C1D9289" modified="2025-10-08" version="1">MPPPPSPFTLRTGIYPEIDPARLGGALACQTALVTGSGRGIGREMALALAQAGANVVVTGRTPKEVDATTKEINALEGTHGTAYGIVANVLDRTDLQRLVDESLGKLGGAIDILVCNAGSNLFQPFHLTDATEWWDLMELNVRAPVELTRLVLPSMRARNKGTLIYTSSRAATADLPWTTAYNCAKTAITRFAGTLQAEVDQLPALEDKTPDVANAIRCYSIHPGEIETSLHDTAFPQRTKDKAPYVIEHMAKIGAHRPHYEGVLPAWTVVWLCVPSEAREALKGKYVDCTRDVVEQSKAVAGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKT3</accession>
    <name>A0ABR3YKT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056840">
        <property type="entry name" value="HEAT_IPO9_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF9">
        <property type="entry name" value="IMPORTIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25018">
        <property type="entry name" value="HEAT_IPO9_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="22"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1003"/>
            <end position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1092" mass="119702" checksum="C5BA1C175799B6C4" modified="2025-10-08" version="1">MDELVRLLSDTQRPEEEPRKRAELDLKAAQANPAFPSLLTAIAATPSYPTQIRQSALTVLRQFIQRNWTPGGIGGDDDDDDEDDATAAAGRIPISDEVKQQIRSQLLELATRNEDDRRVQAAVSFVVGKIAGVDYPDRWPDLLDSLLNVIRSGTDSQLHGALRVLGDLVDDGLTDTQFFAAARGIVEVLYQVAVSGDHKPLLRALAVSVFRSSFDLMDMVKDEHLKEVKAFAQEALQGWLPFFHDVMKLQLPLDQPATTNDGQQSESWNGLVALKLQCVKTLLKIKTVFSSLLLPQSPQFFQETWQELALLKGAYSSLYIEQDSQSRLEDADGLPYTLDFLVLEELDFLNQCIRAPPVQKQLNEELANSGVPAHDTPWLAELMSLLLHYARITREEEELWDIDVSLYLSEETSVTANYTARTACGDLLIKLNEWLSLRALEGLYARSRSLFAADQPGAGDWRAKEASLYLFTMLGGDMLDCGNPVPEDIGNAYLALVEPAIAADQEALLQARGYLAAGLISESNPQALRYLDNTILAVTKAESELVQVACIKALDGFLQAHPPQPGSGIVSPAERQVPILQALNDFLGARDPSDLDEADDLLATLCETLRRTIALEPRIILTNDAVPSIDLLFVIARLGARNFHVTLIVNDCFEEIVEALSQDPQWYVALCSKVIPTLNGFFSFSDLTQDEPLITMATELIAVLVQNGTEPLPAGFVAQVAPKLKKLLMESDEGEVLRPGAEALKYMLSHDHHQMFEWHDEQGNNGLVVCLQIIDRLLGPNIEDNSASEVGGLAAELVEKAGHQRLGDGMLQRLLQAVANRLSSAQAAPFIQSLILVFARLCLTAAGEVVAFLSQITVDQENGLAVVLGKWLENSANFAGYDEIRQNVIALSKLYDLNDPLINQTQVKGDLIVPTSDRIMTRSRAKQNPLPITDFFTVPVKDPDQYTIIPAPLKIVKLLIEELTSAQGKSGAASLEVGGSAAAAAAAEAMGKDATKEAGAGDENGDGEDDDDDDSGWEDETDDILDLSLGATKNDLFSYLDGGPANRRSRDDETQAYLTEFFLRAAREDAGGFKSWYDQLTPTEQQKLNELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLJ9</accession>
    <name>A0ABR3YLJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="30679" checksum="F5835A06D211C9DB" modified="2025-10-08" version="1">MVVGAFPLSGKIAVVTGAGSGINLAFAKQAVEQGARVVIADLNLTDNAKAFAAANEKSVVFAKTDVTKRADLENTVTVAEKTFGDVPDVYIAGAGIFEPDWSSFWDDTEDDGYKQVDVNVNHPMKLSRIAIKSLVKHNKPGVILVVASLAGYQGAFASPLYCATKHAVVGFVRSLADLDELQNIKVTLVAPGYVHTPMWYEDPAKMKQFDYKPSMAVMPEEVAQGMVELVTQAEYGGGACLQVAVGEKRTLGVWNIPAPDTDGARVSKETLEVNYKPVLEKMRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLV7</accession>
    <name>A0ABR3YLV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_009303</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044976651" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="301" mass="31665" checksum="5ECC4FFECBE88204" modified="2025-10-08" version="1">MVSSSSILCAVSTAALFASAWGGKTTSVSNWGDNPSKLPEILVYTPDKIAEKPPIIVALHPCGGTGRMYIGMTPLPSLADKLGFVILYPTSNAQQGMNCWDANTAKSLTHNGGGDSQGIAGMVAWALKTYNGDASKVFVVGDSSGAMESNVMAATYPELFAGAASYSGVPAACWAGSPISTPMSSDLSCPLGKKASTYTQKQWGDLARGCYPGYNGTRPKMMIVHGTADTAVVISLLKAQLDQWSDVFGVTFSKNVSDDPIKNWKKIVYGDGTKLVGYEVQGGGHMPAFQGEETLKFFGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YME6</accession>
    <name>A0ABR3YME6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bactericidal permeability-increasing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1889020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF4">
        <property type="entry name" value="DUF5923 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like N-terminal" evidence="2">
        <location>
            <begin position="235"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="1">
        <location>
            <begin position="648"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="809" mass="88470" checksum="C0CF0E47D4789D4B" modified="2025-10-08" version="1">MYLCGINCCGSASDYDDADAREDGERRPLLANGEEETQHQRTLHQKLHTYQMVRAIGDGYIPSTTQIAANLRRLHTEADRHRQSDLSPSGQRLSLLSEKWIDQLITLLERKNGGDQIQDFAWCVRNARLNVDVSVDADDLGRIGSQAMYRAGQAAGYTSATYQSLQTVTTLLLTNAPFRLFLADLTAVGRDVFADTARSLADASQQAADNVAEVPADNIVSAQEVDGAVPAKETVAAVTDEVVAGASKVAADAQQSVSAKLVDNDDGARERLLGRLKQAVGTLRQRPDYANSVSTLTLLLQKYAAGYVKAAEEVVDAVEEAVDEIRDGPGTSGTVTTNEEADVALRNFWSFLTAFGDPEAWKKLEAQFCALLDRTKGDSQQVDTFVRSVGQTLQDMLTDPAFFDEPEAHLGALKKQGAELEEQLSSSKTSSSTSIRQDLDALLGQVKMTLQSVADDKDVANLASTSTRIADILWPAEDGYVNTDLLSDAVSVYVPRLVQTIQYIPIPRLEIVSNDVDLLLEGLVLEPGRHHDVHAPALRGSPSEPSSFLPYRLQVQIRNDMDIHQTHVGARHGTGSSVSTSATIKIKGLSVAAEDFGYVLRVHSGLFWFNDEGIASFHLDERGVDVQLDVDVVRGTADRLLKLKRVRVHIHHLDFTLRKSKVSWLAWLFTPILRPLLRTTLERQIATSISDSLQTANQELVFARERLRAATIAAGGGSSLETIVPVIRAVFSRFQASVEENPDMDVSIGFQEGATGVFDGVYAPGSLVRVWREEAEEAQARIVEEAANGSYKRDGWRNGIFDVPVDFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMH2</accession>
    <name>A0ABR3YMH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052567">
        <property type="entry name" value="OP_Dioxygenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202:SF1">
        <property type="entry name" value="HD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="37"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="217" mass="23691" checksum="BBD6D7FBB1AFE510" modified="2025-10-08" version="1">MELPTERTPESVVEYIISVMTASETTPYIGEPISQLQHSLQCAAQAADAVPAVDEATQVAALLHDIGQFAPARDIRALVSKSGQQAEIQNLGGQPASQSVGRVGHETLGAQFVLALGFSSKVARLVESHVAAKRYLCAVDTSYMDRLSDASKRSLMYQGGPMSGDERDAFGAEAWCQEMCQLRKWDDEAKVENLVVRDIESWRPALLRQLRENVGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMP3</accession>
    <name>A0ABR3YMP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.230">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="359"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="42008" checksum="7951446CE516AFCF" modified="2025-10-08" version="1">MSDDLCGPSTALKSFSEHVNRDRSVHQDRAAPGRAGPSNFRSVPNGQNSNEAEARAFAAGGAAFQADPMMGPDMAMNGHMHHPPPPQFQQMGPRFVGPSHGHAVNANNWAAEFASTNNAGPAAAAPSLAGNAPAHASPYAPQQAVNRLQHFSSGMMAQSPSFLPSSYQPNFAAPQTFSSFTPQPSSAFAPTAAMSHIPAPQFATDNVPLANDVLANTPSGVAGLTEAELEARFAAFDTADDGFEDEMGAWMAQHGPAAEQQGQTATEQEDVDAIMERMADELDAQRLAEEEPVTDDAIAEEAAAEAEREAANLVKDQDDLARTAGQIVSTLDSNSRFQQSSFLRLMRRIQDREVTVQGDTLVDGAGQPIEPATTAAATTTNSADQDPAGQPQTNSENQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMQ1</accession>
    <name>A0ABR3YMQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HIR complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HIR1_2</name>
        <name evidence="2" type="ORF">Sste5346_009441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="112" mass="11402" checksum="6B67CD1C8BA7E305" modified="2025-10-08" version="1">MAREGTRSQTGHATPRVFATVDTAPVIARKKSTKTKPAAKPAVPAAAKPMGVTKKKAAPKKEKEGAVAKTKAAAKKVVKKAAGKTETNKNKAPSKAPPIAAPKKAEPVAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YND2</accession>
    <name>A0ABR3YND2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224438" description="Thioredoxin domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41049" checksum="5DD3DCF6E9BE6D06" modified="2025-10-08" version="1">MRFNTPTLMGLLAIVPFASAWKHVTDEHLRERLASAGFTLVAFIQPHEAASKALESEWLAIQSAPEGEHVVSFDCSEHASTCRELDTVSTFPAIRLYHRDGRIDRYRGPHSLTSIVPFLRRSFRPAVFEVTENSLVGFMTIDDLVIVAHVHPDDDHLYHRYRQLANHYRDRYSFGVAFTPPSSVSKEKKTSSVVRCYNNADDEQHELAGDTLHAHLGALEAFITETCAAPLIPELTRRNEADFVAATTASGAQSILHYLTEGGDADKDVFRESVRPLAKKYKEYVRFAVTDLGAYPEMMAAFGLDPKVSRGLALQNLVTGELFPYRSGAKKLTAVSAGTIVENFLEDIADGNVKPLTGGDQRFQGGHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ9</accession>
    <name>A0ABR3YPQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008318</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="57"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="500" mass="55249" checksum="BD33E6A5069DE175" modified="2025-10-08" version="1">MASTEKNDMHEVEEAIADQSSPEKAQTQSGINTCAWDNELGDPALDRRVKWKLDFFILPVISSVYFFAAMGRSDLGNAAVAGMPQELGLNAQAYSNAATMFLVSYIVFQLPGTLLVRAIGPPIQFFGAMVLWGLFTILSVVIHSAGALLALRFLIGMAEAFVQGAVFYLSFFYRYNEIATRGAIFFCTSTVAGAFNGLIAYGIEKNLNGKNGWLAWRWIFLIEGILPIAFAFVVLTFLPPSPYKIRFGFTPEEKAHIIARSAAAHNVSDSEYKLQWKRVPLILLSPHFWLMAVISSCGHFCVSSLSNFLPSIIKSFGYTSVDAQLFSVIVYACAGFGVLFWARISDMTNARSVTLGASIAVSIVGYAILIGVTNNKVRFFATCLVAFSVYPNINLQLSWATLSFAGYTRRGSSLAFFNIISQCVSIGANQAYNTPPYYRKGQASSLALCAVGLVFTILTRLYMQYENNRKRNMSEEERATLRVKGIEELGDRHPDFLYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPW6</accession>
    <name>A0ABR3YPW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="589"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="862"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="879"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="894"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="931"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1056" mass="113963" checksum="38AF906864943213" modified="2025-10-08" version="1">MDDMSSPNSSNLSVFDSGAGTDVGIHDDETSPFSSTNDKGITIGFANREGSIRSSMSSTASSRPVMLLPATERSNSISNSSANGSLSQANGENANGTIQQRKRRSKKTAGEKKDSTTSATSDGKEGTVTNAAGKVIKRRAARACVSCRNRKVRCDVVETFPCGNCRWDKIECVVQEGRRRRRGLFNAREAAAAGPLPGAEAFTGSHDHSGHNHSHGHNHGIVNGADINGFDSGFGMGGADATKVAAALNQVNGARSSFDFGGQQRIGGNPLLLPKGPTPQTASADPATAPIGLPGFPLLPINGLLGDPQQQVANLLPGFIRPLPGKMAPEDIVYLHSKGAFTLPDITLQKALLHAYVEFVHPYMPLLELHPLLETIHERDGKSGTVSLLLYHAVMFTAASFVPAKYLKAAGFSRRREARKSFFMKARALYDFDYETDRLTLVQALLLMTYWYETPDDQKDTWHWMGVAVSLAHTIGLHRDPRTTGEPIRRQRLRKLLWWCCFMRDRMIALGMRRPKRIRSEDADVPMLTPADFEKAILPEDIDVVPVECRLVRDVEMQEQLAELCVEKAKLCVLVGNMLQQQYTILPRGRQRGSDAGSSNSTMMLFPNRPVSDDGKGNGPSVVDKIDAKLRAWLLALPVSCRYAALTPADVQNGRATVAVQRTLLHLVYHTTMSALHRPRIQPVAVGAPMLPIEQQEFSRARVRDAADCVTRMGGEMLRLRLEPYLPTAGVTVFLPAMFAHLLDIKGGVPRERRQQAVLGFLTCMRIMESLRETYAAAEIAKGFVESLLKKAGIDLAAVANFSDDSTPSGMGIEGEGTGTSTPINGASASLLNATSNVGVPYTEDGIAHAVAMYAANTPKAMSARTTPPADNNIGGHRGSTSGSDSAGYSTSVNSNSHSNQNKNNNNNQNQNGNGVNNVNNNVHNGHNNNLMQGLQSHNNNNAASYMPTSVAAAAARLMAVGLQQPGNTSMPMSSTNGIATANTAVEQMWGLTPSGSAVSEDPFEWDVTAADPTTMKLDFDQWLDFPPEGMGSSTDHAFVGLFNSDFGNDMMNTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQD9</accession>
    <name>A0ABR3YQD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secondary alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038966">
        <property type="entry name" value="TMA17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422:SF1">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="24868" checksum="4F2E3DCA6D3AE982" modified="2025-10-08" version="1">MSSETLPISPVRFAEAIKDLSLASLHLKILEIRNDVAHLDYSNEQLLPYAKGDVAALGETEAAPDQDCVDAIKENLVVIERKLNQLKLVRAEVENRGVSWTEFQSKEEAEQQQAESDQRAERTSSALAAARQPVANGHTDAATNGSATTTSTTGNPWTDGTFQTGTIRNGELEMDSVAGQSFATRNGSGSNGAGGGGGSLTDEQLQRALEERLGLSTQNGNSNNDDDEEGLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRB5</accession>
    <name>A0ABR3YRB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008269</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF139">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="74"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="59515" checksum="4595560C3E2C3406" modified="2025-10-08" version="1">MEKPTIIDPSVEEKMPVSDSDKAGSTVGGIVTNNVDAINSLATRLDPAGNPLSPTPTSDLLDPLNWPLWRKYVCIAIACFSYFLMTYLTTAPIPSFFLLEDQFNATYNQTNWTFAISAFGLIFGPLLSGGLADIYGRRICMIVTTSITLLATGCTSIQSQSLGAYMFERFLQGLGAGSACNLGLSIINDVSFQHERGQRVGLWAIAANTGTFLGGVFGGFLVSINQYWVAYQVTIAYGVLWLLTVFFLPETLYPRRQMLNVEFGPAGSNSIEAPSPRTSKLPFFNVHKIAGLTYPKIYSPWVVVFRLWCYPTIVLSIMSYVFFQYWWIISLMTIEPLAYEDKSPQVQGLLFLGFVVGLIFAEVFCSGHASDKLVLYLVKRSPTGERTPEMRLWLGYPAAVISAIGCGLWGLSVDREWHWMLGQLTFFLYAVGLQVGNTVLTTYMVDNYPTYANELSIFYSCIINLSAFLVPWFIYAWVEFNGYTWCFAIQGILCILVIPAYIALQKYGAKWRKPANFGVYNEDEYDPTVAVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS37</accession>
    <name>A0ABR3YS37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="28"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="37226" checksum="19735ECF2CF778AF" modified="2025-10-08" version="1">MASIETDAPRIVVSLSIMTGVAFVFMVLRFFCKVRYHKKFGVDDHMLAAAWVCLVAYAALTITSTNYGIGLHINFISSQDLVTALRLLYVGRFIAIIALAISKTSFAVTLLHLAMTAWQRYVLWFIIVSLNVVMWFSALSLFIQCSPIQKAWDLNSTGTCWNPMVQVNIGISAGAYSALMDFSLALFPSVLIRNLQMKKAEKYAVIFAMSLGVFAGITAIIKTYFISGSQRSKDFTFTTANLLIWSGAETAVTIIAASLPFLRLLLKEATSKNKTVNGRPDTYYLEEMTRTDGARGASMTRASRPPQDDESEKSILGETKRGQLRIERGQAKIDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSD0</accession>
    <name>A0ABR3YSD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="117" mass="13060" checksum="46F3CB34DE9EF9E2" modified="2025-10-08" version="1">MAAERTQWRLVTVNTAPERAKRLIGRMVEALKDQYDIQHVDNCDNLDQVLPKVTQHKPNVLFCASMWTPEQSAQAFATARSVVPDIKTHAIPEGLQVKNGPDAVVDYLIVEVPKLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU4</accession>
    <name>A0ABR3YTU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38347" checksum="FB0C7EE49FAB28FB" modified="2025-10-08" version="1">MANRRQHPLSVFTETNYLHAFVSPNYVKHVFWAQWQTVPLPKPGHFAGQTVIVTGANVGLGLEAVRHFARLGAARVIVACRSVEKAEAAVADVRQSLTAEQAAAVKLEAWDMDLGSFASVAAFGKRAAKELDRLDAVVENAGVAAGTYCPLEGHESSITVNVLSTFYLAFLLLPLLRQTAAQHNVRPNISIVSSDAHFFARFDEQYKPSIFAALQDPASMTHDRYNVSKLLEILVVREMAKVLDDKKIGITVNTLNPGLCRTQLFRSLPFGVRHLVNGGLVLIGRTADMGARTLVSAAAAGPETHGEYLDTNEVWPVSTYVTSEAGAKAQGRVWTELLGILEGIHPGIIKNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTX7</accession>
    <name>A0ABR3YTX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">cAMP-dependent protein kinase pathway protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610:SF12">
        <property type="entry name" value="SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610">
        <property type="entry name" value="SINGLE STRANDED DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="500"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="608"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="515"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="640"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="674"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="687"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="710"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="756"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="785"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="817"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="902" mass="94247" checksum="4372B18A720D356A" modified="2025-10-08" version="1">MANMAAMTGAVGAPMGMMNNVGVPPGAANRPQPPQNPQQAQQQQQAQQQQLQQQQQQQQQAQQQQLQLQQQQAQQQQQQQQQQQGMPQGQPQQGQPQGPAQGLPMQEIGNRTLLNTYIYEYFLRYEMLDCARAILGQKVNLQKDGPDGRRDENGNLINGVGDDAMDTDSKDFADAKTVEDLPTPNLPMPSDSSFLFDWFCLFWEMFNAQKGKGLHSGVNQYTQHMQSRLRQAQQQDMLRQIRPDFQQQQQQALMMRNMQNGGMLAMKQGNNLPRTAMANSQNIPQGMNMLQAKQGQMQRDPSDLDGNRARPSSPGSGENAPSPSKRPRLDSVPFNPNQAALMQNGRPVAQGMPGQQVGAGPIHPHVQQMFLANGVNPASLSAEQLQQFSQQSPAAQAKNIQAYSQNLQQHHNAQLPNKAMPNVSGPPGQGSPMMPDGASLNAFYNAGELAGPAAMRAGPGAPPAGGGSNHALQDYQMQLMLLEQQNKKRLMMARQEQDGIVGMGRPDGTPVTAGTPGGPGQPGGPGGPGGPGAPNAGQPFQGSSPQGGRPGASPNPADQMKRGGQMAGNGMGSPLPDNPQSRGSPNPANFMNAHMDPNMAPNFFKVDGNMAGQQMNGGMRTPGAHPGMPFNGPMNPQMMAAARQHQQQQQQAAAAAGAGGQQGGPPIQWQQGGAPNGGGPMNGPQGGAPQQAPQPQGTPQQRAMPPPSAPGAAAANAAQRATASPQTSTAAPPTPQTAAKANPKKKDGKATKKKPQTAAQKKAAATPAGETSAADAEPPTPATPITPGNPASFNGGKPAGPAVSGPPAGAIVPNGQPTAVSAPGVSAVPPPAQADPNQNSAFGMDNTSMTFGLEFADPMASSDVLNDFDFDTFLHESNEDGGGFDFGSATFGIEGAGEIGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTZ5</accession>
    <name>A0ABR3YTZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methylenetetrahydrofolate reductase 1</fullName>
            <ecNumber evidence="9">1.5.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET12</name>
        <name evidence="9" type="ORF">Sste5346_007634</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="8">
        <location>
            <begin position="440"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="708" mass="77925" checksum="472AEF50CF8A7850" modified="2025-10-08" version="1">MEHKITDKIAALSPDSFYFSLEFFPPKTSMGFANLRDRLDRMARALRPLFVNVTWGAGGSTAQKSLELAEICQRELGLTTCLHLTCTNMSRELIDKALEDAKALGIRNILALRGDPPRPTEYSDDTDKDAAASGIASGSEELEFTFAVDLVKYIRKQHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLPYLVEKVQAGADFVMTQLFFDQAAYAHFEQLLLEHPSGAFQDIPLIPGLMPIQNYQMIKRTTKLSHARIPDALMDRLDAVKKDDEQVKSVGVDIISELVEQVKEIKDRTRADKPKGFHFYTLNLEKAVSFIIERTHLIPPGTPDEDEEAIAEVAVVDDVAVTTNARGVPSIRINGSTGTGSGAAVVLSPLDGHPARRQSSIGSDPRNRVIVSGRTASHPDYEATALEAGIPAEPVNTRSNTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMTVNQALRLWGRPTKTEDINAIFIRYLGGELAAIPWSEEEFNPETATIRDQLVKLNTKGWWTVASQPAVNGIPSTDATFGWGPPHGFVFQKAFVELFLPSADWATLHKRLTDDPAVRDNVCFYAINAAGDFVSSDASGRVTEGGSAAETVVEPSTNAVTWGVFPGKEIITPTIVEEVSFRAWSEEAFGIWKEWAALYPKGSPTDILLEKTRNDYWLVNIIHHNYIEKDSLWDLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUC0</accession>
    <name>A0ABR3YUC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="10">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IDP2_2</name>
        <name evidence="12" type="ORF">Sste5346_007310</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006156">
        <property type="entry name" value="PRK08299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="11">
        <location>
            <begin position="9"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="410" mass="45990" checksum="3769F57FA1611B09" modified="2025-10-08" version="1">MPKIKATNPVVELDGDEMARVLWATIKDVLLLPYLDVDIRYFDLGLQHRDVVDNAVVAEAAAAIKEHHVGIKCATITADEARLKEFGLKEMWPSPNIALRSALGGTIFREPIVIPRIPRLVPRWTKPIVIGRHAYGDKYRAVQRKFEGEGKLEMVFTPTDGGKPETIQVFDYPEGGGVGLAQHNTTKSITDFAHACFRYALLRKLPLFFSTKNTVLKVYDGHFKRIFETLYETQYRPQFEEAGLTYEHRLIDDMVAYMIKSDGGYVLALKNYDGDVQSDIVAQGFGSLGLMTSFLVTPDGRTMMTEAAHGTVTKHFREHQKGRETSTNPVASIFAWTRALMKRGELDETPRVVAFAQAVEQACIETVDLDGIMTKDLAAACGQTNRESWVTTTEYIKAVDTRLKKLVEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ3</accession>
    <name>A0ABR3YUQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="497"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="550" mass="59852" checksum="A3BF2AF02DE65F01" modified="2025-10-08" version="1">MATAALISPNTPYYSHHPPSSYSSGGYYQQQGQHQPAHAHSHSQSHGGHNHGQASPSTVAAGMISPVESRRTSDDHDMSGHRQSLPSLKEVIGKNASSSYHHPPPPSSTTPSGPGPQQSLPSPFSTTAPSRSFPAESPSDMQHSPRTLHHPASIPPPPSSSIYNHNQQRPESASSFPAPPRPPLSGRVHGSPPPNESHQGGPPPPSSVQSLIHSQQPPSQHAPSYPPHPSQHPPHPSQQQPRHPQDQPPQLPPYGHHQGPPPRDARSAHDDSPPPHHAYPNAPGQQPPPYPPQSSSQQPLPPPPPHQAHQGHMSASYPASPRHSGPPSLPSPFESHQQPSMQEPPVDYNRSRTRYDQAVSRHFESWSYAEYLARIGSNSRTIYNFAEAFGSIAREEHGPHPMPGRMPGDREVCEMISNAEWLKTMLESLRHMVQHTVSEGSSGAGPGSAGGASSSGAGRQKLANMDDMDMPMYNEPGTKPYGMEVKKRRGRAAPPGRCHSCNRIDTPEWRRGPDGARTLCNACGLHYAKLERKKQLESRQIRPKHPDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ5</accession>
    <name>A0ABR3YUQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="55667" checksum="006B443AA176C843" modified="2025-10-08" version="1">MKAALDAAAVHYMARRVLATDPSTSPGSSPEQSGPVGTVSTAIVVPQPISPPKAVTTGSTSSPEDMMADFNNVSISVPIMATPTTTPPNLSDDAIVASTPLIRQPRATWDDASMCYFLGEYRVAPQPGIIIGHMDFLSDMLFEAPLDSALRPATLATACLCFSRRRDSLELYAQSRDHYGKALKAVITSIEKGPDHWGDDTLASIMLLHMFEDIDSGHSHNATSHLKGIARLYDLRGQNLLSKIPGSPLYGWIFTHLQTLSLATNEFFECLSIPQPERAVTDPAGGLVYMVAKISRFITLSAERQSALDKANAPSEARRTALMTMMHLAMRTQSETDAWAESLPKTWKPRVVFALDESGNTRRLVTYSCRWLSVVSTMYHASLVKYYHTVLSCCQSILELHVSPTPAEKDLINATANMANKNLAHLIAMICDSLPYAFGEVDGDGELLPAPDYKGYSSYSLIWSLELVSTYPGSTKEQIALCKSSLTRIGSLYGIRLAQSPQNLAAFTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUR7</accession>
    <name>A0ABR3YUR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Potassium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">KCH1</name>
        <name evidence="4" type="ORF">Sste5346_007615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031606">
        <property type="entry name" value="Kch1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424:SF1">
        <property type="entry name" value="LOW AFFINITY K(+) TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16944">
        <property type="entry name" value="KCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="228"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="471"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="685"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="727" mass="78183" checksum="9B9F35E5A18A6983" modified="2025-10-08" version="1">MGFLSHGNKADVRPEQKWDYIGLQDFKSTSCFTPFAYTYLYFSLGLSIAVYAVDTFTAVNLLVFDRWSSEIAPTQLISFAVSKWIFSICIILSVVNLAYEHIRAMRIMRRGSVAECYLDNLAVRLESVRWGKGQGWKRFLVFAELTKSKKGAEYIALFTYFSFQSWIRVLLCSGPRQVVNALTLLSVYNAQLSASGDNVGNTLLDFFDKIRTLAEGNSREAVILSGMIFTLVIWVFSFLSLLLAVLFFLFFLWGYIPRSDGGLSGYCSRKINKRLMKIVATKVNTALAEEERRRKKAELKAAKKNGVLPPTELTATLPDVGDGDNKLPMMPQLQRNDTMTTLPPYTSRPGTAAGGPGGVGGGPNNGSTFELNAFDQKRPMMPPTRSGTMASMSTLAAPTPTNPTKFSARAPLLGYAAEPGRSSSPAPSLPEMGDGLPSGIPSGMPPYGQAPPGPGQLNRTNTGNSTMPYGNSNNMMRSNTNNTMNSRNDSFSSFSSNQYTPNQQGQPPMPRMPQPVRSPAGPYGNDGRPPTAGSYAGRNNSQGSQDFGYNNGVNANGRNNSLSSNGPRYAAYRPDEGRASPAPSARSYGPGAPGGPAGPGMMSPMRSATNPYPVSPRNNGGYNNGAGVGAPNGYGAPQRNMTAPMPQMGQGQNNTPLGHGRQISEESSYSSYFERPTTASSQRAPGPSGLSGPGSTVGSNVAPRRPSYGNNSNAWNNDVESQRGGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVF6</accession>
    <name>A0ABR3YVF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="126"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="405" mass="43736" checksum="9D36906D486E0429" modified="2025-10-08" version="1">MPPKKVPSTPGEGPAPVAAGSSQSSSSGAALSSSRRSSAYDGNFESHMDDFKILAVARSSRPSNLVEVVAALRAPREEARDAVTEDDFARLQAAYDRAFDEDDVVTIILPLVVGPSDWFEHNSSRNVLCNNLTPLTNNTIVSIKPNVYYGAPSSQFAPDVRATLAAHIIPTAAAPRPLLPNFFVEIKGPSGTEIVALRQVRYDGAVGARAMHSLQNYAAVRDGLPRSAHVYDGRVRALSVTLFSDRLRIFGHHITAPAPGESRPTYHMTRLGGWLLTEEFDQFRQGVYAYRNARDLARRFRDELIAEANNVARISGVGMATEEANEAATVFPDTTGQTGQTDQTDQTDQTNSQPSMAPPAEPASRVASKRPLDFTTADANDSGPASKTNRSSHRTNATDANNETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVP2</accession>
    <name>A0ABR3YVP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ALG7</name>
        <name evidence="21" type="ORF">Sste5346_007657</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1891394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="510" mass="55652" checksum="97AB51BF0C4125BF" modified="2025-10-08" version="1">MTSSASSTRAASPNGHGHAPTPPLPPTTLKQENAALAAGIPSVLSNSETYSLLALTVACATVLGNTVRRDDGAPLTASLALSGIAFAATYAMIRWLGPSFVRAGIKGADLNKVQRRTLPECMGAVCAVVYLLAIIVFIPMPFYKDIVAATSGGGNRDVVLPEIVPAAHVEQGRLLHRFPHSKLASFLSAIISLQSITLLGIGDDLFDIRWRHKFVIPAFAAIPLLVVYFVDFGVTSVVVPTPLQPYLGELVELGPLYYLYMTAVAIFSPNSINILAGINGIEVAQSVVVAALLVFNDALYLLAGPYPHPATDSHLFSLYFLLPFLGVSLALLVHNWFPARVFVGDTYCYFAGMVFVVVSILGHFSKTLVLLLLPQIANFIYSAPQIFGLIPCPRHRMPRFHARTGLLEPSVTAWLPDRQPKPPIVWALRLLARLHLLRMTTDPKNPEIIQETTNMTLLNLWLVWRGPLREDRLAIEIVVMQTLVGLFGLFVRHRLALLIFKEDNLGAVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWS6</accession>
    <name>A0ABR3YWS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20909" checksum="2A32918EFF19F17C" modified="2025-10-08" version="1">MFEALYPHPEDRLQLRLHRARSVILTSEELVEIRAAQRTFEGAYMRTALSQFSFALVVLKIFTAEFYAIGALFAVYGAAVMLVAIYRRYEGNRQFFSTQEEAKEEEDNGHGDYYDEAVDGEQPGDHASTTGAQPHITHSGQRSTAYTRMVTKKKFRTSGNSVAMLSLLSIAAYVSLIVLLWRLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWW9</accession>
    <name>A0ABR3YWW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="627"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="870"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="682"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="733"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="872"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="958" mass="103635" checksum="CDDB99A0D0B680E2" modified="2025-10-08" version="1">MDGGQPHAPKPAGSGSPVDYSTHQSPPPPASHAGTVGTAGSPAQYPNVESIDAKVSTSTDQSPQGGSPATQGNNANAQRIIKRRSPVACRRCRRMRSKCVHNGAKPPCEGCRAAGVSLDDCVFPARGAPDMDREYRHPRMKGDKARKEGNRANRAQLSGGVSASPGGRPPFDNGAMTTEGGVPLPADPWELLPPLEQVIDAVDMFMRQYFQLGFIPRHTFVQQLREQPQSVSVFLLLSLLSVSARMTPSLVEAYGGAGPTAELFMDRASAVALTELYQEPTLPRCQAFYLLSLAQQGSGYRNRSFVNLGIALRMAILMQLHREETYALENPTQAMIQKAESARRTLWMLYSQDNLHAGPLAPIALAACDITTLLPSNEEDFNDGVIPKTRAALEDTPPARAKPMLVNSPTRSLFASLMQSHQLWGTVLRRAVTNNRNVVPWDSNSEYSAIKQKLNDWESRLPTEHRWSRELLRHFKSQNLDLAYMAVTMVTRLCNIIIRKAYLPYMLAEKGPKQQQEYWRTMSGELFRNVKDLFTQIDCWIEEREPGDGTGAQLAIFCVYSCGLMAAYLCKYPKLCPDAATTREGKHMLDRTMGILSQSTSVWPLARRWMESVEKLLAADTKSLTVSNSHEGGMAEGKDPIPSALHPPLASLAPSGPSNTPFDDRRQLARQLGPDSPHARSASPSVGGNLSNGHGGANGTGHGPIHLPQLRTDASLINSPLRLPPPQPSPNLVTNATSSAPHYSTAPPALALPPPAPHNLQLGGGMRTPTSFSHGQNTPHVQHLPQSPSHQGAEHMSQNGMPGVSPAQQPHPPSMAQASQGHHPDGRINGMVMQRFDGGATNTTEEAEAAAVLASGMVSHGGVMGYGANQMHHQQPQPQPQHDNPYGAQHLPDHGHGMHTDPLTGNGIPMMGQMQATGFYDPAMLIDLPDDGFQGELQFFTQGTAQAGAPWASGVFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXG4</accession>
    <name>A0ABR3YXG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006897</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF18">
        <property type="entry name" value="NICOTINATE CATABOLISM CLUSTER-SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="357"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1084" mass="121384" checksum="94DAC4F575F21E37" modified="2025-10-08" version="1">MAAVSDDGSSSTGAGTGAGSSKPASTATPKNFVCTRAGCNKRFTRDEHLQRHALNHTAGDYTCSRCRAHFKRPDLLSRHLQRHRQRDLEVGAEGYGVLNTRKRAWKALDGTVVQKKPQLTTPATPPEVHEVHELHLLHDTATSIDTSTDTSTDTSTGPSSEWADRLILAAGHINTTYHNNNNNLNTDDNNNTTVDALYAAEATISPAQTQSSSAQLSSTHSSSSCQSDLADAEAEQYDVSQSQYEYDQSRLYLDPALEHQQQQHQQQQKVQFTSIPPFASVSIDSIAGVGTGAVDSTSYTQRPVAPELQQQQPPPPPLDFLFDDVFQPDTASSFNMPYTTAINYNWLFSMDDNTIDSTNIAEPSSRPVQSSQTMQTMHQQMSLQSLQEQQQEQRQTNADMSLDYLVISPASGSGSSQTLVFDDPRQNITSPPMMHPAPPSQSSQSHVEQDRPSGGIFQEKLVPPPSMHGTERLRLERPLSSIHPVHAQHFPVIDQETRERLLQVVDACHPALPDGQLSTWDHPLLALDSLQDFYHLFFSRFNTAYPLLHQATFHPSETEPLLLLAVVLLGTTYSSKEAHQLAVCIHDVMRPRIFAHTDFGAKPSLWMLQTILLVECFGKSRAGQKQHDMSHLFHGLLINLIRRSDCQSARPSVSVWSDHDHETLTSEKVEEAWKKWAVQEEMKRLALLCFMWDTQHAVLFCQSLCMSAFELRLTLPCSQVLWESRTAAEWKRITMAEQGTGQDFLFLTALKMYLTPPTADRPSTFQQLNLNALSRVLLLHGLLSISWDMERRDQTALGVVDGANALVSSQSGRDWRDRMADAYNRWKTDFDTYCADLYDCQQRQQHQHHQHELKGDQTAGDKTATPTTQHLEAAARECSTFATAYKAVYHAAHILLNSDFLDVQIYAGARHILGRPVQRGDFIRSERVIKRWAAAQVHHDGDATPAAKAAWHAACLVHDAARHLDDFDAMGLFHVPWCLYIATLTCWVFHHTRHRPTDNSSWSSRDDSSEIVWDARQEMDELVANMARAQPSNLMRTQGQQQTGGLVWVMANVLSNVRWGIVHAGVVVLRGLVPLRMISQYEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY32</accession>
    <name>A0ABR3YY32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="10">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="9">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="primary">PUT2</name>
        <name evidence="12" type="ORF">Sste5346_006838</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07123">
        <property type="entry name" value="ALDH_F4-17_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="11">
        <location>
            <begin position="106"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="598" mass="65226" checksum="AAEE638FA733BBB5" modified="2025-10-08" version="1">MASRRLSSAATARLLSPSLRRLQNQQCQHLPFSRQAPVFSSRPQLRMSSIATFKSPSVSNEPNHFYAKGSDQRAGLTAAVEKMKAAGPVDVPMVIGGKEVRNKFTAEQKNPADHKTTVATYSQASPADVKAAIEAALAVKEEWAAVPFADRAAIFLKAADLISTKYRYDIMAATMLGQGKNAWQAEIDAAAELCDFLRFNVHYAEQLYAQQPQHNSAGVWNRSEYRPLEGFVYAVSPFNFTAIAGNLSGAPALLGNVIVWKPSDFAIASNWLLYNIFIEAGLPKNVIQFVPGPPEEITRTVLEHRQFSALHYTGSTAVFRKLWGQIGEGTAEGRYIGYPRVVGETGGKNFHLIHASADVENAAVQTVRGAFEFQGQKCSATSRIYVPKSLWPQFRDRMVAETEKLQMGVPWEHRNFIGPVIHQASFDKLSGVIDAAKSDKELTLLTGGKYDGSKGFFVQPTIYETSNPAHPLLSRELFGPVLVAHVYDDKNGSTQAFADMCDTIDATSEYSLTGSVFAADRSAVRVAEERLRNAAGNFYINCKSTGAVVGQQPFGGARASGTNDKAGSPTLLNRFVSTRSIKEEFGATTTVAYPSNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYG6</accession>
    <name>A0ABR3YYG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CipC-like antibiotic response protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13596" checksum="C5547F92C40B3683" modified="2025-10-08" version="1">MGFFDFDESRNARDQVYNNDNHHESSLSHELLGAGASFAAMHEWENHQRAEGKTVSHGFAKEAIAALAGAEVDKLVETKGLDFIDREKAKHHAKQNAERLYDQQYGNQDHFDPNGPRPNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYH7</accession>
    <name>A0ABR3YYH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large subunit ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006652</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33512" checksum="0676FC137F2E225F" modified="2025-10-08" version="1">MASQRQCLVAMASTAMQATTRPRPHMALAAASSIPRFLLPSLSMSVQQTRHASQKNNKQPEKKTVYKAYRIRDKAKLQRYSLCDAMRYLRAYEVGRPPLSTCYELAVKIQTNKTGAVLRDRIRLPYPTSSDFRIAVVCKEGSKIATDARIDGAVAVGEESLFAAIKAGEINFNRLVCHIDSVPELMKAGLGPILGPKGLMPSAKTKTIASDVRAVMRDIAGTDNYKEHVGVVRMAIGMLSFSPQMLGDNIKVFMDQLKAEMRSVSHTSAKVIDEVVLSTTNGPGFSLNGNFNPTDESVTVAKLSSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYL9</accession>
    <name>A0ABR3YYL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006536</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="189"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="54607" checksum="82A9441B0B12A5ED" modified="2025-10-08" version="1">MASDLFTDGTRCIDTYPFVYAGPPRKRVFLVDTPGFDDSTRTDSELLRELAAWLSATYTRDIRLSGIIYLHCINQPRMQGSAKRNITLFKKLCGDDALRNVILATTMWDLVGEDVGAMREQELISTPAFWGYMHSKGSNTYRHHNTHASAMNLIGHFIKTERKLTLDIQAEMVHQRKDLDGTAAAATVAAQLELERARFTAELHNLKTELKDAVRKKDHDTIDMLQEARDKYESDLAQIKLAHENLRASMQTLHEERYANLERAMKEQQETYTAELSAADQRLARAQTSTNAAPLAADGVAETPQAYGAQGADASTAETFGGREEHPIIIWDNMTGRHVSSLYSHTDEVRSITLSSDGKRLISESLYITDLGSEKKVWDVTTGTCLLTTSDYITVSSDCTRFLKTAGNSIQIFDLATGRCKVTIELPPPYTIEQGVYFSADGTRAMCQSKEYIWTWDTETGQLVSKVYEYYSSYSYYEWSESMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYP4</accession>
    <name>A0ABR3YYP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-hydroxyacyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF3">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="4">
        <location>
            <begin position="7"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="3">
        <location>
            <begin position="192"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32310" checksum="4EDF60B4BC3ABFFF" modified="2025-10-08" version="1">MTSSRGVTLIGAGTQGTRLAYMWSRCGRPVHVVDKDPKQLERSAKEIERLRKEWPLSSLPGERGGNTDWGKATFIQPEKLESAIQQSWLAIECVPESRPLKKSIIQQLDGLAPPDVIIASNSSSYTISEILKGLTLRNADRFASIHSYWPPETTPVEIMGAETTRPEIIERLMKESTAHGFQPFHVRRSSTGYIYNRIWAAIKRETLLALDEQVATPAEVDALFKAVLKTPKGPCEQMDTVGLDVVLAIEEHYAEERPELPTAPRDLLKKMIADGKLGVKSGEGFFTQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYW9</accession>
    <name>A0ABR3YYW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="78" mass="8458" checksum="4E7B9CB964774837" modified="2025-10-08" version="1">MTLAATCHCGNVRITVPGPPEFLNECLCTVCYKLGGVWAYYKTDQVTIESPYRGFPRTFAPTSNAPTWLSAGVRTVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYY0</accession>
    <name>A0ABR3YYY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Delta 1-pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="6">1.5.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRO3</name>
        <name evidence="6" type="ORF">Sste5346_006591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="4">
        <location>
            <begin position="104"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="5">
        <location>
            <begin position="300"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="402" mass="40600" checksum="8FE92833D6BC7480" modified="2025-10-08" version="1">MPAAFNLPIVGGSNSSAAVMSSASSVTSSSTPEHLTLAVLGCGTMGIAILSGILTELAEMDAPRPLQVVTSSASVSSLSALYTASQPANGSSSSSTAAAAAADEMPERLPTHFLACVRRPEAAKRLRAALWAHSSVVKVVVDDNVAAVQQAGVVLLACQASEAHALLSTPGMARALQGKLLISICSGVTVEQIESYVYGETDASSSSALTTTSPTATSPKEARCRIVRAMPNAASLIGESMTVVDTSSAQGPLPADAAALVTWIFRRIGSVVHHPSRRATGVAGTRALATVDRVAASSAAACTALGTAGPAFFALVLEAAIDGAVAMGLPRAEAQLLAAQSMRGAAGLVLQNNEHPALLRDRVSTPGGCAIQGLLTLEEGGVRSTIARAVREATAVAVQEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z024</accession>
    <name>A0ABR3Z024_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="64"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="490" mass="54268" checksum="A93F4FBCAA126B58" modified="2025-10-08" version="1">MTTEPTSYLAQDVKPEGLQIEMTEEAQDSKDVKDFVDPTADYSGAVSKTDPREIALVRKIDFRVMPTLWCMYFMNYLDRNAVANAVLNGIKTDLGLKGTQYNTCISILFVGYIIAQVPSNMFISSANIRPAIYMGGWMAVWAVNSACTALVHNYKGLLLVRFFLGFTEAPFYPGALYLLSRFYTRKELALRISILYSGNIFATAFSGLIAAATFATLDGAHGIQGWRWLFIIEGVVTFTIALISVFLLPNSPMETRWLTPEERQMVVDRINRDTVGMETKTGVWSGLLQAVRDPRLYLFVFMQNMHLSSTSFSNFFPTVLSALGQSSIITLVLTAPPYIVAGVITWMVGISSGKFNERTWHITATMGVATVGFIISCTTLNHGARYFATFLFASGTYAVNSLVIGWIAATLGQTAEKKAVSLAIVNTFANLSYVYTSYLYPASNGPYYKIGMASSAAFSAAMILSAWALRFWLVSTNKKMGWQNGLRYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0E8</accession>
    <name>A0ABR3Z0E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006114</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="461"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="618"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="679"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="691"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="736"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="755"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="927" mass="101065" checksum="0290B4822D9ACE39" modified="2025-10-08" version="1">MADSPPAPTGPAPAYGSPSSLAITTVAPPRPQRTLYFAYGSDMQIAYMARTCPNSRYIGRAVLTDYKWHINGLGFANLTKVKTAHAPGLVFEVDDADKTALEKNKFPLYRSVTIDAELYPAPFCLYRRQATWITKHGGPEAVLEEAYATGRGNDRRASYTERGLLVFISLDVTTDGRPDARYAEAINAAAADAMALGIEPLFFEKIVQQFMPGRMLPYLRVVRRGRQGSVADTGAAATTTPTTDSKLSPVAARQQRAESSRTPSPSSPSPSQATAIIADAVPYAPTAKDRETLAGAAKVIDDAGDLDKFDISQVDIPVWPESERLAAAYAAKERERKEKEKEKEKEKGVKDSKPSGFGETIRTIFNRQRGRRKESNESGEGSGAAAREAREAAGGRRSPLLTGSESGNASGSDDGSTSPTVNTNTAARKRPEIIQTAKGSLYRLQKDPSYYAVAADFPARRNVSASSSATALQGNSATEGAKHSKSQSESSLVDTTTRPPAPKITISRPSRHNTIDRTKWNVDPDDGDEDSTDSEIESEKEKKEAASSSRKTEWRKSRQIVVSPPPRPSRPPPERANPVPSGYVPVYSVAAQKKTAGESVRQVDPAVVGREQTVVPTVGTIRRDTLGRDKTTTEGASGSSSRLAVERKPVKAPGKKRPSTDEVLRMRAAANRAFTAGIIVKNKPSPVEPSEAARKAREVAKEMVDAEREEKAETDTKEIEKTSAPPPPKREAPKGPRAPPTTPPRLPAEKPVKVEEEEDETTETAQENPEETVTEKAEPTQVSAPATRVSTTPLLPRPSPTPAVTVRLPFVPRRPVQRRFGVRQSAAATSTEKEHLLRRPKSFCGAARPLTRFDRFLLQAAEHPHFSEKAWLQVFRQRQQQHSHFAFHAQVHVHTHAHTPRHRMMFAASQTTVVGGAFGGRERRMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I4</accession>
    <name>A0ABR3Z0I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor, Arf Arf6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARF6</name>
        <name evidence="7" type="ORF">Sste5346_006145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="199" mass="22511" checksum="25DA1EB375199CD6" modified="2025-10-08" version="1">MGGQFSKMMGKIFGSKEMRLLMLGLDAAGKTTILYKLKLGQDVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYFSGRQPPSADRRERLRTQGLIFVVDSSDRVRMEEAKQELHRIINDREMKDSLLLVFANKQDLENSMKPQEVTEALQLAKLKDKIWYVVPSCATTGEGLLEGLAWLSNNVKAPPAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1I7</accession>
    <name>A0ABR3Z1I7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056584">
        <property type="entry name" value="EF-hand_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23617">
        <property type="entry name" value="EF-hand_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="4">
        <location>
            <begin position="452"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="378"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="623"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="810" mass="85583" checksum="5C8C03C1363C7BC0" modified="2025-10-08" version="1">MSQPPAAPTAPATAATAPTATVPAVAPTTAPAQAPVAPPPATTATPSTTTAPNTSPEVVLDAALLAHLSRIFASHANEKDNSWHADQVATFLSHVQGSEDDATAAAALDFHGFLRYITSPAADIVAPPAVEDIDSYPLSSYFINSSHNTYLTGNQLYSDASTAAYRHVLERDCRCIEIDVWDGDDSDHEGGSTSSSASSSDEGEAGAAIKSSRKDMVKKYKAKAKEALPASLTARFGRSTLGRRLEHYVEKKIEGKPAKPSAAASGAPGGAATPGEAPPLEPRVLHGHTLTREVSFRDVCATIREYGFKTTNTPLIVSLEVHCTPPQQDVMVQIMEQEWRGLLLERNREKEAQMKTLPSPGSLRNKILIKVKYVAPGGTGTSPEGSAKGVSTSPGTGSPHASDPGLSSKLANIATETSTVESPPSRTTAPGTPTPGGSGTTAKKPSKIIQALSQLGIYTQGVSFKSLSQPEAYMPTHVFSLSEKNVMEVHAKHGPALFSHNRKFLMRAYPSGLRIGSSNLDPVRFWRKGVQIVALNWQNCDEGMMLNDAMFLGTGGYVLKPEGYRGDKLGTPPAPTTAPAVNTTFQPPPTAPVAGSSGKLPFTPKLLNLSITVFAAQGLALPQKADSREGGLSGDADGSSAPQMSTSTRTLRPFVKVVLHVDDHPERPDAPDAGTTGDTEEDDDGEYKAKTHVYKETGSGGGRNPDFAQEELRFNNVPMAALLPAATTTEEAKKGHTTAEASAASAETLSFVRFLVKDTGGAMHRDVLLGWATVRLDRLRPGYRLVHLREPVHGRATGAVVLVKVEKGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1R8</accession>
    <name>A0ABR3Z1R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Armadillo repeat-containing protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="851"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="900"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="960"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1039"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="912"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="963"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1039"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1189" mass="126596" checksum="DC10667357BEC9B5" modified="2025-10-08" version="1">MVLLSQNVAILENLRTAQSYTAQTQALQALKNETVGHVMKKEKWVELGVLLPIVKVILPERPSNWLAGDGREADDLARLQALELLGIFASGGAAFLEPLHAAGALPAILSCIDPKTSHRRLVYAALRSIVTITKAARLISVPASSPSPVTLGTLADTIFNPTHLKAFYNIIVAAPRAWWNESITNAAVSLVSPLCRETHHQVALAKAGILDALAVKVASYVVAKGQVVPGADIAAEKEGLLDYIPEPATSRLDISAVLDAAAAIMGNSRLRACMLLCSPSILAIFPQLEFDSPMNDVHAAWKALSMGGLSNLNQQSLGALDFLLPAIPSQALRGHHHSSHNSPFPPLGSTFARESLSRQFPSSTSGAAKRGSGSRHPSSGEGSGAGAGPEGLALDSEEQESPMVPWLFSLVRSTSGLERLMAASVLTSLYKAGFANKTREAAMAYLVVPLLLRMLGEAVNSASGDGSGGWVGDDDSNKTEHQAITEAALTILARLVTNSDVLQKAAIDGKAIKILAKLLKESYEPVSTRSNPRPWNPTPTASANPSRTGTPVAGTQSQSVGGEWFVEDNETAAGGDADNWAMQIASSKLGPAGQSSQLAYRTRLREATLKALTALVAVKYDYQREFADLDAMVYVSASLNATPSKPRANKDRTRSIKDVEMNTNGNSDDDVDPEYGRNPVGVLVAACDCVRMLSRSIAILRTTLEDAGVAAPIFRLLRHPDVYVQIAATGVICNLLTETSPMRERFAEAGVMSILCTHAHSLNSALRVNALWALKHFVDGQEPGMKKACLEQLGSGWLMQLIDPDSEVDASPSSAIFTGRADNSYNQAGGMAAAVATPSWSFTTVANDEDVEMGQTGDDGDGGAGDYSSNNNEAGGGEDEALWTATATTNPPPAAGVGLGSPSFQRARFPRTSHERSRTGRLRQADDKLAALQEMEIASQRKKQNDEVMTQEQGLNFIRNLIGPGSSSNGTNSSLGLGQPTSAAPRDAISEASEMIDYLFNEIGQDRLFQILLSKLRPKVRPATASRVAVPAVRRRSIAGSSGSGANAGPSTSAAVPGSPSSEAASSSGSRVQQPKAKIVEAVVFILVHISASVSRHRQIVIAQTELLKALVSHFMNRDKAVRVALCHLVNNLAWRDDQADIQMANTRIIEIRRLGLLQQLEIMQFEDPELDVREQAKMAVHQMELTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z200</accession>
    <name>A0ABR3Z200_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168816" description="Small secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="13566" checksum="9CF1F93F0406094A" modified="2025-10-08" version="1">MKSFAVLAAATLALASPVAKRESGGLLLCTGANATGTCDYTVYPLDTCVNITAPFSGNTNTFAPDGEAFACYPYAMPCGGICTSPEGCTLGAIDFDYPNKFNLSAVQWAGVASFRCFTKTTTTTVETEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z322</accession>
    <name>A0ABR3Z322_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S11-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS11B</name>
        <name evidence="6" type="ORF">Sste5346_005652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_uS17_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF9">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS17 N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="161" mass="18471" checksum="DA02C4B3D0DA83D7" modified="2025-10-08" version="1">MATELTVQSERAFQKQPHIFLNSKTKVKTARPGKNGRRWYKNVGLGFRTPKTAIEGSYIDKKCPFTGLVSIRGRILTGTVVSTKMHRTIIIRREYLHYIPKYSRYEKRHTNLAAHCSPAFRVEEGDQVTVGQCRPLSKTVRFNVLRVLPRTSKAAKSFSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z384</accession>
    <name>A0ABR3Z384_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chitin biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAL1894525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
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        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031673">
        <property type="entry name" value="Chs5_N"/>
    </dbReference>
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        <property type="entry name" value="CHS_Export/Cell_Fusion_Reg"/>
    </dbReference>
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        <property type="entry name" value="Fn3_2"/>
    </dbReference>
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        <property type="entry name" value="FN3_dom"/>
    </dbReference>
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        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47351">
        <property type="entry name" value="CHITIN BIOSYNTHESIS PROTEIN CHS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47351:SF1">
        <property type="entry name" value="CHITIN BIOSYNTHESIS PROTEIN CHS5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PTCB-BRCT"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FN3"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="75"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="163"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
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            <begin position="290"/>
            <end position="328"/>
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            <end position="383"/>
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            <end position="400"/>
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    </feature>
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        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="44344" checksum="B03267D6F9D752DA" modified="2025-10-08" version="1">MLVSLTVGKVDAGVTVLLTQDKRLIEFPSILLPPNISSGSIVDIAVSRNRASEQAAKDSFAALQNRIYETFGVDPPTTPVLRCRNATQTSVVLEWDPIQLATADLTSLSLYRNGQKAGNIPRPLQMHSTKISGLAVDTEYTFHLVLRTSAGTFSSEKLVVRTHKMTDLSGVTITTGILPGAARERLVAAVERIGAKLVADPGAVRIDTTHFVTTEGRGTAWEKAVELNIPVVRPEWVEACEKNGRILGVTKYYLDAVRPTGPNDHEPVVPPPQQQQQQPPPQQNKELPQSPADEPSSSATPPAAPASNAAAGSSSSGVTSPAPGAAAANDEEPETRDDQKVWLGDQSGHEQKVALRTKNEVNREAEDEDDGDDGAEDDEDDSDDGHANGSGNGAAADSSSLNKPATPGDGNSFQDVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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    <name>A0ABR3Z389_9PEZI</name>
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        </submittedName>
    </protein>
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        <name evidence="8" type="ORF">Sste5346_005658</name>
    </gene>
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        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07387">
        <property type="entry name" value="MPP_PolD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
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        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
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        <property type="entry name" value="PolD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="7">
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            <end position="224"/>
        </location>
    </feature>
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            <end position="538"/>
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        </source>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="581" mass="62560" checksum="0A920FE037824B87" modified="2025-10-08" version="1">MVSLDAAKSLLAAPLCVAQFDSKISRSKIMGFFLLASFIVHTDLSPSSPDEPLPERVQTAYVPLHRFDLQNSRQYQQQFADMYFLRLAKIKPAVDAVASDVFDDVVVGGAKAKKVERVLDVRQGELCWVSGTVYMDMPFKPSILEDVSKDKLLSKPSTVKKYVPEDNDDILAEGRGSVAIMLEDDSGRIRLVGRPLRSVLLVTGCIIAVMGTENEDGELEVIDIMFPDLPPQPERWQLSKPVATNGAAGEGPPAKKAKIEGGGKNGASGDVVMDGTAERKSSGGGKKIAIVSGLNFSGPHGASAVETSLLLEYLLGEALAPGSQEEASHISRLIIAGNSITTPEDPEEKAAKEAATAAAAAAAGSDGGVLQPKKYGYDSASYNPVPSALLDEFLAELLPSMPVTLMPGVNDPANASIPQQPIHPAMFPNARLYTSPKPPSLAAPTDPPGWFDTVTNPWEGEVEGWRVLGVSGQTIDDIHKYVQGNDRLSMMEATCRWRCAAPTAPDTLWTYPYQEDDPFVLDTCPHVYFAGSQPEFGTRLITGPEDQTVRLIAVPAFSETREVVLLDTETLEVTRVKIGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3S9</accession>
    <name>A0ABR3Z3S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Involucrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="904"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="795"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="911"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1106"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1134"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1237"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1324"/>
            <end position="1336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1440" mass="153278" checksum="F9F7E935956468B9" modified="2025-10-08" version="1">MGIFSFKRGGDKKKKGRAKEEEVEIEKDMFNQAFLGDDPYLRGGVKGPATEIYAGDGFLPERAATPTLRTGKLTKKPSGGALNQPSRPWTSGNGAQRQRTGSFSSMSGGRGEGSGSGSGSHNGGDYFRSKGRSPLDSDVDVRPSTSHGPGSKPWSHGHSFSAQFGPAAGRRPQTPRGASGFGPSNAAAGPSSSSDPRSGTNSPTRSGMHNSQSLSDNNMSTSSSAPTETSESSIQNSSNDDQRAASPPSTVSNRSPPSMSPEPVWPLQNSKKLSADGKIGGGMLSQSSSFGDEALMAVNEAAGRAAQPLPAPQPEVMVPAPLNPRSRDATPTSPPGSSQDSRGRKARDAAKQRDLAIEVPKRRSWGAQIDQLEKSWMVEQQSPGGARAPQRPNGQHRQQQHPQSAPYYQQHHQIPDPSQKHSSQQPHPSQRPHRNDPRYDPRYDARNDPRYDPRYDPRYDNRHDPRYDPRRQQHQLQPQSPGYGPGPGPGPRSQSSHGHRPPPNSSADPRDHRHYGNMGGGPYAMARSDRQPSPGMPRPSNRPASAGRDGLRRMGSDFDLQQHRIPYGNPPQGQGQGQGLRTTKSMQQLPRSPRDYPSMNNIRGPASPQGPGQPSYGHQPRGSSMSPAQYRSPPPFVRSPPGNGVRSPPYTTPRSSSGGDGGQSRTRTPQPMPLNSGPGPSSYRDPSQYGPLRSPLGSPPHMSNGNGYPADRSGQHPVVDNNHPNNPIVYQPLDRPVSGGSSSGGGGGSGFQSFGPPLPDVAEVVEDKPTGAEGTEIKDFAIKEEPDAEEETEETTTTATTPTKTAPPRPTRSPPVSVALATTTKLELPESQSTGSLDKLTLNSFPLPSRNVSPIPPSSSLPQSPRSPRSPRSPRSPTADTKQEAGLAGLAVLNKTKDILAAAAASKEATPVKSSTPEPTSPVTVKTSSPVVEKAVVRQLASPEQKDTSPDTPTEESAEFEAKSVEEKQVSRVSTPVAIAEKQEEISRPQTPDSWKPDVVNAHDSREIVQKDVHEDTHDFQDAQEEFESEHHQEDGDNIVETELERTSFDSEPPLSPISLPSGDAEPSLTANWPLPAVFISPPVVEEQKTTEKESERIVEKVIEVPATITSPTPATPMTPSTPVTPTTPNPAIDLDDEDDDRGEADEDELFPNLKASPTKSKSAFTASVYARDIGLGPYAFDADNTENLPTEAHGLTAPTGAPWALPARLDSLEKAPQQKLVPRPESEPKPEVLAPSPSPEPPAVPPKDAPQVEVEEAVATEALPTPQVIGAFPETPDAVEKDNNDNQIDDALATQAASPESEYSWGGGDAGRGLVDDDSDAESDGHHHLDEEDKNFGPLSPDSIGLARGPSIIESEADSELLESPSKGGMKRWAIASHLAGGVDGDAVLHERIIGVGGGVGNGSSAIKGDGPPKLALGQLNFDRHTPTGMVDSFGTTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z455</accession>
    <name>A0ABR3Z455_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Transaldolase</fullName>
            <ecNumber evidence="3 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TAL1</name>
        <name evidence="8" type="ORF">Sste5346_005437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="324" mass="35063" checksum="14570917E871651A" modified="2025-10-08" version="1">MSSSLDQLKATGTVVVSDSGDFASIAKYKPQDATTNPSLILAASKKAEYAKLIDEAVAIGKKAEGSLDQKVDATLDAILVEFGREILKIVPGRVSTEVDARLSFDTKASVDKALHIIDLYKAQGISKDRVLIKIASTWEGIKAAEILQRDHGINTNLTLMFSLTQAIAAAEAGAFLISPFVGRILDWFKASTGKTYAKEEDPGVASVQAIFNYYKKYGYKTIVMGASFRNTGEITELAGCDYLTISPSLLEELLNSNEAVPQKLNASGAAALDIPKKTYISDEPTFRFDFNEDQMAVEKLREGISKFAADAETLKDIIKAKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P5</accession>
    <name>A0ABR3Z4P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Chitin deacetylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_005068</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="4"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="11">
        <location>
            <begin position="83"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="38062" checksum="649A3A99C6F67805" modified="2025-10-08" version="1">MPAGGACGTQANNAVCAAGLCCSDSGVCGTGGAFCTAPACQISAGPACDGNQTPKGADTSKVPRPLFGSIPYGVDISHCTVNGKVALTFDDGPYLYTAALLDILRSNNVTATFFVVGNNGAKGMINDPATGYPAVLQRMVADGHQIGSHTWSHQDLSALTSQQRHDQIVKNEIAIADVIGVIPTYLRPPYTRWNQDALNDLKALGYHVLNYDIDTRDWQGNYTVAESIYSSILSQHSPTSSAWISLEHDIYNTTVHVFAQYIIDQARKLGYQLVTVGECLADPVSNWYRNVTTGQPASPVVGAAVANAGGGQTTSASVTTSHTTTRSKTTTTIGSFPSAIAQQNQTVYSCLHKVARLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y4</accession>
    <name>A0ABR3Z5Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686:SF1">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="406" mass="43526" checksum="852A5A75A70AAE06" modified="2025-10-08" version="1">MALDEPPRPPHLAPLRQVLPPLLLGTATFNTQYVDDPTVMPYRGIVRRALVDLGINAFDTSPYYGPSESLLGEALEATGVERSRFFLETKAGRVHGTGFDYSAPAIQASVRRSLQRLRTPYVDLVFAHDAEFVSEGEVLAAVRALRALRADGILRYVGISGFPVDVLASLSELILRETGEPVDAVLSYGHCTVQNTRLLGDPVTRMHKAGVSVVLNASLLNMGLLTTRGVNNGPQAKWHPSPPALRDVCAVAAQVCKDEPEPASLGMKGIEQVALRYAMDVWAREGARSQVDTVSAGGSLGIGASVLGVTTEAELDETALEWWSVLDGLGLPHFALGGLQSRAGVGSAPDAASRQKNGLERTAAVKKFVEEKLVPVFGELKDFSWASPEEGWVNELNPEVAAKARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6F2</accession>
    <name>A0ABR3Z6F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-dehydropantoate 2-reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005521</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF26">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="20"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="244"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="41220" checksum="1430D9C70B96E78E" modified="2025-10-08" version="1">MAHHSPANVPAADPTKPVHIVFVGAGAVGCFYASRLHYPDHNIHVSLIGRSNYAALAKDGVQLQTRSFGNYVFHPHAVYPSANAAGGVPNSSTSSDVPPPPPGGWDYVVVTTKALPDRVDDSATIAPLVGPKSTIVLIQNGVGVEAPYRARFPDTTIISGVTIISAEQVKPGVIRQNRWTRLHIGPYTTSAESSSSSASPPSASVDPNSALTKRGTEATERLTDWWTRLGGIRDIDPLDEVGLQTVRWHKLCINAAFNPSAVLSGGRGNADMASDPEMRIHLRAIMDEIWAAAPRILGRPFPSELATPDKILASTDRNKGARPSMLLDWEAGRPLELEVIVGNPVRIARARGVELPRMQSLYALLRSAQSVREQKQKEAKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z803</accession>
    <name>A0ABR3Z803_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="159"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="220" mass="24746" checksum="8D53BC5082C27287" modified="2025-10-08" version="1">MSNFIVWRHLAPKPCNEEAVLKTLAAVVQHARTDREAVVGIWVWQQVADDSTGVLPWVYGETQHRPFTGELPAIMIQEIYRSEPDYRAFSESAAYVSNVVEFKTLLREPPKEQNLTPATGFSFRPNSPYSTTEDLYVVAARIQYNPGTVPAGVNCWKTVTSFVEQSEKEGTLGYNFVMDAADPSALYSLEVYRDLAAFDVHKIRTGLTIRVFKQVASSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG7</accession>
    <name>A0ABR3ZAG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003954</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="13"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="363"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="392" mass="42095" checksum="3620244B31442C04" modified="2025-10-08" version="1">MTADPVQFVTYCGSKANRVVPVKTTRSVGPNDCLVEVTHSGYCATDTYFTAVPMGLGHEGVGVIRRVGPAVKQHKVGDRVGWGFVHEACFNCKQCLSGGEIYCLKRKIYGFGNLDQGSLATHAIWDENFLFPIPDAMSSSVAAPLMCAGASVFGSLQQRGYKSTDRCGVVGIGGLGHLAIQFAHKMGMEVVAFSTTEAKRAEATAFGADEFVVIPREPGTRLSGIRRIDHLLICSTAQPDYHLFLDILEPRATIYPLTAFEKDVTYPHLDLIFSGVTIQGTMIATKQGFIDMLKFCVQHNIKPANQEYPMTVAGIEACNTDLKAGTMRYRGVLVAEGADRSSETAIEPEANTKAEAEAEPETVTEITVVVDGEKNGTNGTNGTNGANGKAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAJ8</accession>
    <name>A0ABR3ZAJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Borealin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_004265</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the borealin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018851">
        <property type="entry name" value="Borealin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018867">
        <property type="entry name" value="Cell_div_borealin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16040">
        <property type="entry name" value="AUSTRALIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16040:SF7">
        <property type="entry name" value="AUSTRALIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10444">
        <property type="entry name" value="Nbl1_Borealin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Borealin N-terminal" evidence="11">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="82"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="222"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="226"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="371" mass="38784" checksum="337DAE0DB96BB421" modified="2025-10-08" version="1">MATKTEESPSKRQKVGVTIAQKQALVDNLQLEVTERARKLRAQYNLQAQGLRTRIEIRVNRIPMALRKLKMGDLLLKHSTDQQMPVASKQATAAGRAPPPVPEKDFNQARSVVSRAESRAAQTAVNRPLKRLSDQLASGDKENQNSHLDNPKKRQRGAPGTSHGTQPGQILSPASSNSRMNPRDRERGAPPPSSPAKSFIARPMSPTKQASATNLISSMVEKARATRAATTRKPTTSSTASSAAGGATATAARTRGRGAASGTTAAPASRSAAAAAARNARRISGISESSDASTSTVVRKVGRPAASTTASTARKVTGTTAAATKKTVMSSIKKGVTSATTKRAAATKAAAPTAATASATTRSGRVLRKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK0</accession>
    <name>A0ABR3ZAK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF1">
        <property type="entry name" value="AROMATIC RING-OPENING DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G00640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="8"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="287" mass="32047" checksum="389B4C1295AAD5D7" modified="2025-10-08" version="1">MANLTPVHFFAHGSTMMLGEESESADYWKKCGDEALAHSIKGVIMMGAHWAAADDAIEVSMNPKPAKSPVAYVHPSKYQNYDLQPDLPTGQRCVKLLREAGFRARGNPTFDWIHDTYLILIRMFPGGCPPTTIVSMNPRFDPHYHMRVGLAFRRLRAEGYLLIGSGGTVHNLYRNVWYPMVNYCDNFAQPTPPCDWALGFRQSFEDVINYGGGPRLRLGITRLMKHPQFRDAHATDDHYMAACFVAGAVGAREDEGTRGELGAEDWELTNMCNSQFTLGAWDVAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAR8</accession>
    <name>A0ABR3ZAR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Leucyl aminopeptidase yscIV</fullName>
            <ecNumber evidence="11">3.3.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LAP2</name>
        <name evidence="11" type="ORF">Sste5346_004083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.6" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004463">
        <property type="term" value="F:leukotriene-A4 hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="10">
        <location>
            <begin position="482"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="628" mass="70001" checksum="96CD2488D9F1E00F" modified="2025-10-08" version="1">MGKRDASTAANYNVWRNDHTTASLKIDFDAQVLRGHLVQDFSRQPNTDGEDASEIILDTSFVDVKAVSVDGKAVPFEVKPRTGPLGEPLHIKLPAAAASAAVGTSVRVRIDVSTTAACTALQWLTPAQTSNKTAPFMFSQAQAIHARSLFPCQDTPDVKSTYSFRIASPHPVVASGLTVTDATAQQVAEDDDILESVGTKDTLYVFEQKVPIPSYLFALASGDIATASIGDRSIVATSPDQLKACQWELEQDMPKYLDVIEKLVFPYAWGEYNVLVLPPSFPYGGMENPIFTFATPTIISGDRQNVDVIAHELSHSWSGNLVTSGSWEHYWLNEGWTMYLERRIIAAIHGDAYFDFSAVIGWKALEDAIEGFGATHDYTKLLIKHDGIDPDDAFSTVPYEKGFHMVYYLERLVGRANFDKFIPYYFKKWSGKSLDSYEFRDTFLEFFDKPEFADLKDVVAGIDWEGRFHTPGLPPKPKFDTTLIDVCYKLAEQWKSKDFVPSPKDVEGWVANQKIVFLGEIQGFADPITVEQSEKMGAAYGLVDTQNVEVKSAYYVVALRAQDKSTYQGTADLLGTVGRMKFVRPLYRALNKVDRPLALATFEKNRDFYHPICKAMVEKDLGPDANRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB93</accession>
    <name>A0ABR3ZB93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="187" mass="20219" checksum="1E84200CE0A310F3" modified="2025-10-08" version="1">MCEFTQREYSCGHFKFIAARWCNLYKRTHRRCQPDIAHFEYRADEICGQCRPQEVPAWQHLIRSNAPVSITGITGINSLDDCCRNLHLVPWLGADRPGSCTRRSPTPGPGSMAPLSLSSLSSASRSGSGMGATSSHSSSSSSSHHSSSSSHHSSKSTTGTATTVGSNTVLSGKIRRHSSRASVTLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBF8</accession>
    <name>A0ABR3ZBF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="263" mass="28486" checksum="F45EF253037BD5AD" modified="2025-10-08" version="1">MPATTTQPDRPSAAAEVAAALNDGKTHLLLAASGSVATIKLPLIAAAFSRVRNLSIRVILTPNAAQFLQGQSTEQPPVDSAALRGLPNVDAVYVGDADEWHPPWTRGAPILHIELRRWAQLLVVAPMSANLLAKIANGLCDTLLTSVIRAWETDPALAKRILVAPSMNTAMWNHPLTSRQLSTLRETWGVKPARLSVTVTDEELSNAEEEEEETPGWYEILLPQSKALACGDVGQGGMADWRDIVLVIRDRLSLSPEYFTDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBX1</accession>
    <name>A0ABR3ZBX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="272" mass="29391" checksum="D959346615A83BCF" modified="2025-10-08" version="1">MPLAMPSKATLVALSLVPVVAPTAYLLLIRATTSRYIAVSATQKRVLTPKDKEDVAAAEAASTSTTTYSPDTTIADTIPPHSIPDEVFADSASYVVYCERVVSKPVPIKSLTVEGGDASSGALLTTYLRGTMGAFAWTPMGIIMHRIISDPALRATFSADHLESLNFAKDDIACGPHKVTYRSRDRAEMMTQRLADKPDLVVHAVIVAAVETTASGNEVVFVNETWFWRHAQEEPPSMLETAAGRWLHTLVGGWMIFKGTSKVTASVKAKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC21</accession>
    <name>A0ABR3ZC21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="494" mass="54218" checksum="BD9C26C8A0636DAD" modified="2025-10-08" version="1">MTATTAAAAVAAAVDSIPVSLTDQHRPIPNIRTRTFFIVKARLDADALKSGLDTLIREHYRKLGGRLVLNSATDMFEYRVPNTFPPADKYELFLWSTESKAQSIEAAAPDLMKTPPVETSEGGGGIAFLPAVTHYDEQFRPASWPYDFNEGPKDAPILFFHLTLYEDATVIAISLPHVVGDQLGTASLMRAWMNVVAGQAPPALMEEDPMPAGREFSSLTKEEARRKGKMRVRRTGEYAFVIMGFIPDLVFNSEEAHHIMFLPMTTVKSLRARITKALQANGGDPGISDNDVITAVLAKLSRAHKGPTTMTLSQSVNLRGRVPKLTGSAVDGFLHNGVAHASSRFHMDKNTSLAEIAKNNREAIREMMDPATTDIRLAVAREMVRRKQGMHICEPFEKSYSVTSWPAAWKDLDFSPAVAGHTNGSGDASSAQTPLQPPEVFVIGRGGERATPHRFHSTVMFRNDAGYWCDIGCTKKNLAAIKAYLAQDPKLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ1</accession>
    <name>A0ABR3ZCQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="254" mass="26532" checksum="563D934146F024DC" modified="2025-10-08" version="1">MSASLQGKLAIVTGAGKANGVGFATALTLAKQGADVVIHYNTSKDAALKNVAALEAVGIKAIAVQADASSTAFGTDIIAATTAAFPGRTIDILVNNAAMITAKPDLASFTPEDFDTIFNVNVRSIFLLIQAAEKYLTAPGARIVNISSVVARFGIAPGNFYGGSKAALHALTRGWSEYFAPKGINVNVALLGPIETDLVFPEDNPYTQRFRHDQHIKRNGTTQECADAILFLASPGSSFVTGQVLNIDGGLTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK0</accession>
    <name>A0ABR3ZDK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF24">
        <property type="entry name" value="NICOTINIC ACID PLASMA MEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="50"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="53462" checksum="7A61D2F77ADDF553" modified="2025-10-08" version="1">MSDPTSVDKDIKAADMPTAAVQDASSEEGTTIYISPEREAAALRKFDRWLVPVAFAFLVLSSLDRNNLGNAKTFGFSTDLKLTGNMFGNITTAFSVTFIVFEVPWVIAVRRFGANRALGLCLIMWSAITLATAFVKTYHQAVAVRVLLGIFEAGISPGFAYLFSTIYPQAEAGKRVMMGNLANCTSGAFGGLIAYGVQSMGTRRGLVPWRWLFIIEFCFTILIGGIGLAVLPKTPEDAWFLSEEEKETMRLRRQRDEAFRGADGFDWKWVRMCLTDSYILVCALAFFTSSVAINGFGVFLPTIIQGLGYAAIRVNYMTIPVYVLGAISLITNCYISDRMNRRAIVLLWCCIPVVTGYLICVGTANAHAGYAGMFVLVLGVYPISTLVVAWMGTNLSPDNKRAFGLPFFYSIGNLSLLISSQLYPSTQGPRYVQGNAVSAGLEVVAACLYASSWFILRRRNALKKRLIAEGATTNGKEGDRALDFTYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK8</accession>
    <name>A0ABR3ZDK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxidase</fullName>
            <ecNumber evidence="5">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045007527" description="Peroxidase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="6">
        <location>
            <begin position="159"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="361" mass="38126" checksum="4375C7A1A641B562" modified="2025-10-08" version="1">MLRALFLSLLFLALQSHSVNAYPGFHTLLWDLHGHIARQVAADSGPSTILLADLAEKGVTTPVGRTIHDILRGNTTAIVDPSVTYTRPDAVIKAGLGGLDHPACGTDTCCIWSYIVPAMVDAFSENGGTRCSALARSAIRIGFHDAARSENRGLANIADLILSWHSEFSQYSPNPPSVADLIQVGAIVATVTCPGGPRIRAFVGRPNFPKKGPAPPEGLIPKPTADPKTIIAMMAAKTFTTTDLVALLGAHSVSRQFFTDLEFAGFPQDTTDGVFDTKFYAETDAPSAPVGVYRIASDVALAGDPMTSALWKNYSGSDAATQSRWTGAYASAYVRLSLLGVANLNGLTDCSGVLPQSKALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDV0</accession>
    <name>A0ABR3ZDV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Superoxide dismutase</fullName>
            <ecNumber evidence="12">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SOD2_1</name>
        <name evidence="15" type="ORF">Sste5346_003679</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF29">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="13">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="14">
        <location>
            <begin position="102"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="215" mass="23522" checksum="4ADB6323FF8A27B3" modified="2025-10-08" version="1">MSAKIYSLPALPYAYNALEPSISAQIMELHHKRHHQAYVDNLNKALQSLTTAVAAGDAATQVSLQEAIRFNGGGHINHSLFWRNLAPAGNPESDPSGTAAPTLVKDINQTWGNVENFKKAFSTALLGIKGSGWGWLVLEPATGLRIVTTKDQDPPVGGEIPILGVDMWEHAYYLQYLNGKAAYVENIWKIINWKTAEERYLRGPADAAKMIAEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL9</accession>
    <name>A0ABR3ZEL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">White collar 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013654">
        <property type="entry name" value="PAS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF7">
        <property type="entry name" value="GATA-FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08446">
        <property type="entry name" value="PAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="649"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="786"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="1000"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1040"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="286"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1081"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1094"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1128"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1149"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1173"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1182" mass="126302" checksum="C2513621ABCCA10B" modified="2025-10-08" version="1">MDSFYNDQLPLGMDGVQQQQQQQNLQPGPIPNAGNNDGSMMNIDDSSFDANIFGQNSQSPSIVGRRHSLPHTQQNFPPHSTEQARMSMSAAAFRALGADGGMPMLDFTSGASGVSSSGDIHSAVENAFKTFSFSTSDSTIGFPMSTMPGHTAGLPQTTAEQQQSVAASQTTTGFSTSSGMLASASPDLNNFNSLSQGMIDSMMAYPGLNMSQMGANQPSSLDAASLAFFSTADPESGNTPVSSLGFTSGQSDSLSFAPAMDMDMSGGMSLINSGPSPTQPQPQQQPSPLDLFTAQSQSSHATPSSSTSLARSQISPLQQQQQQPVQFPSRFAQSMASTPSMNDIASNASGPRLSHSNSVGQASVPRASSTSASASSAPTPAQISSGGPPSTRLSTTSMGTMATGPHQPPITTKTIKNYYSSSGFDMIRALYYVSSRPNPEISIGPVDLSCAFVVCDATLNDCPIIYISDNFQHLTGYSNHEILGQNCRFLQAPDGRVEAGSRREFTDNKAVFNIKEKLMAGREVQQSLINYRKGGKPFLNLLTMIPIPWDDCKEVFKYFIGLQIDLVESPDAISGNSSDSMRIDYKHRTSIPQYIWDPPKTGHWNTNYGRTLGMDDVSALLQQFGNKGLMSSKGVGSDIVGSATSDLYRQSWDKMLLENVDDVIHVLSLKGVFLYLSPSCKDVLEYDSSDLLGNSLSSICHPSDIVPVTREMRDTQVGQPINFVYRIRRKRSGYTWFESHGSLLVEQGKGRKCIVLIGRKRPAFALHRSDVDINGGIGDSEIWTKMSTSGMILHVSSNVRSLLDIQPDSLVGTSMQDLMRKESRAGFNRSLEKVRRGVIASCRHEVQHRRGQVFQSSTILYPGDAERGQKPTFILGQTRLLKSSSSRSSLPSTVGTSSASGIAMTDVEEIGRAGAIGQLAEPDTQTGGFVSSAGGGAIPLGSQDAILAADDNIFDELKTTRCTSWQYELRQMEKANRLLAEELGQLLANRKKRKRRKGVGNVPRDCANCHTRNTPEWRRGPSGQRDLCNSCGLRWAKQVGRVSPRNSSRGGGSTTIAGGAMTDAVSKKSASPIHASPLQRDFPHDVHVNRDNSGGESSGSNHSPGTGPTSGNNGNSSGSSGNVTGNTSGSGGDTSGGTGTGSSSHDSSYLLQQSGLHLQQPQVPPSTGTEMTSIREEQETVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFM8</accession>
    <name>A0ABR3ZFM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium/calmodulin-dependent protein kinase type I</fullName>
            <ecNumber evidence="7">2.7.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cmk1</name>
        <name evidence="7" type="ORF">Sste5346_003117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.17" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="15"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="434" mass="47536" checksum="5402AD07CA4A776B" modified="2025-10-08" version="1">MAAKAPPPQVQPCRYKVGKTLGAGSYSVVKECVHIDTGRCYAAKVINKRLMAGREHMIRNEIAVLKKVSMGHKNILTLVDYFETMNNLYLVTDLALGGELFDRICRKGSYYESDAADLIRATLSAVAYLHDHGIVHRDLKPENLLFRTPEDNADLLIADFGLSRIMDEEQFHVLTTTCGTPGYMAPEIFKKIGHGKPVDIWALGVITYFLLCGYTPFDRDSDFEEMQAILQADYSFTPVDYWRGVSDAAKDFIRRCLTIDASKRMTAHAALQHPFLAGYDRRNAGASGLPAGQTDETNLLPTVKKNFNARRTLHAAIDTVRAINKLREGGLQGRMDGARSREPARNNGNANRAPAPQAPQAPSANGGNGVPAMRKDDSGYGTQIEKDGGLGNNDVDMSDAPPLHAVPMSLRPGMEVNKVVETTKGLWTGVGSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFQ6</accession>
    <name>A0ABR3ZFQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051631">
        <property type="entry name" value="Ankyrin-KH/SAM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206">
        <property type="entry name" value="MASK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206:SF7">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1182"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="93"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="491"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="663"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="909"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="942"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1033"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="391"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="535"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="550"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="909"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="952"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1285" mass="140465" checksum="FFE8076353A9F188" modified="2025-10-08" version="1">MAPANPTVRELDGGSSVGAGSGGSGSGGGSSGKAGGKGSSTVPGRIGRPPQWTSTRSRKLVRLYMYSTLSVDKILKVLEDDVFKPRKNSAQKTIHNMLDHDPRYLRPESREDMNQRVKLLAGSTQRKRRSWKKHGENQQQHQHQQQNQQHPHAQYQQPPPPPPMGHSSGYDDGMSHGIKPEMGHGSGLSHLPQHSQYQHVQHHQQHSQHTQHQQHSQHPAHSYQQQLQHPHHAQHQQPQHHQQAQHQLPPQPHDLSQQYPSQTSPTYLPPPQNLHQHHQQQQQSYSDFYHTQVQQQAPPPPPPPQHQQYPLSMQQMTTHNVPPFVGGGWGGVYDNQPQAADPASRLTMNSSFDLAQHQTGMAPLHAQQQHPGHSQQNLHHQHAQHAQQHQQHPHAAHGHPHHHYHPNEHGGIDGHGNLSTLAGGITSSHLPLFGEHQRQRRMSSAAHSTDSDASSDVSTETIQDLKNRLSGCSTHYANQIANLLRRFTISNGSDDPSSPSPSVVLSGPRSGSNDNGADPHRIRKLWRQKTQRIRSSSVSSNSSSGSFDVFDSDVDVYGEAGEDDDTTRRGQSSHGGSNPASVNGGASPDGRDDEHGRLRRPGGLRSGASKTTASTTANVTTILGASGNNAGNPRLVLPGDFFNAYQYRDDANCPFHNKEALMREEQEKRQRQAEEEQNDRRGGRGSANGANAKSPREKRCWCAIAEAVNAVAAEDGSFWVLADGRLTPDAQAMVHEPTQQRHQLARRDRFGHSMLHLFASREGLQMQLLAMVLNCDDATLLAANTAGQTFLHVLAPGWFVGLHEPYSPLVQLLAHLRSRTRQPPTISSGADAADDPNRPGSGDAIAHLIYATDVYGRSFFHRFGTFVSDPNVITNTIIQHYDRAALSRRDAFAHVPVAIMGAGGSVSSGTDEYGNWQQQSSPPTKMHMKRQSIPSLQFLGQTLSPRYDDDGQNQNQTLVGGSPSPTATPALGGGNVPTVFSSEDAFIRHHESLLRTVTASDNNPSVEDPEGRNGLHCLAEAIVDKRIMDDHRNALSAGRKPPKKKTLDKKDPNAVSTSSSSSFMNGLLLGGESGSVSDGISSGPTYSSTSPYMNNPALGGTQSLLHTSSDGAQMATRLRLVQGLLSPPIVVDVNHYDRRGQTVLTAFVVHIADDQEDKAKSLVAILETLLSAGARIEGRNRRGETALLVAARLGRKIALTTLLDHGANVHARDAAGRGVLDVLDMQCRRQGRNNVALYGRLEACRVLLTSIKQLPLGVKQRPTLMDEWTIVHRRGPEPRDITMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGG6</accession>
    <name>A0ABR3ZGG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002883</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF3">
        <property type="entry name" value="CLC CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0868">Chloride</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="273"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="898" mass="97473" checksum="1780CF0474DD8F4B" modified="2025-10-08" version="1">MAEAAFGATPAHGSSSHLSSGPPSPSLSRHHRLSRRGSIAADEPPDERTGLLQSQRSRTMRQPNLNRSHSYAGTATRHHSRAGSWSQRLINVLSDRQESMAESKASIAPDERVWYDQFTSTDWVHDSILDAYRVKALRNRKDFWGRVYVLFDGAQGWVLSALVGFVVAVLAYAIDVSEAVAFDYKYGYCTLGWYMTEKQCCPNGHCTDWREWAEVLGAQGPGEMWVEYGAYILGVIFFASAACLLTLTTKTVVPSAFRLSTLDENLAAEPVSLSNDDDVADDGDNGAGSSGRRRYGGVDDGNGGNSSGSTPPPPENKSSQSLPPMVYFSAAGSGVAEVRVILSGFVLHGFLGFKTIVVKSIGLVLSVASGLSLGKEGPYVHIATCVGNIACRLFTKYDRNDAKRREVLSAAAAAGVAVAFGAPLGGVLFCLEEVAYFFPAKTLFRTFFCCITAALTLKFLNPYGTNKIVMFQVQYPVDWEYFELGSFVAVGVIGGVAGAMFIKASRLWAKSFRGIPLIKKHPLLEVVLVALVTGLVGYWSDLTKLPVAELLYNLAAPCDITDNNLQNLGICPTEVNDIPPILLKLFGAFLIKGILTIVTFGIKVPAGIYVPSMVVGGLMGRMVGHVVQWVVLSTPTWSVWGTCPAVGEATCIQPGVYGLIAAGATMCGVTRLSVTLAVILFEITGSLDYVLPFSLAILVAKWTADAIEPLSIYDLLTEMNSYPFLNNKHKPVFTSDLADIVPRVRRNRVIDISSSPLVKATVLRQKLESLHRAGELDGGLPIVRHDILVGLIPAPDLEFALDNLRDEASSLCLMASVPSIDDSDDNEQGIDPTDFTPYIDPAPVALDIRSPMDLVYECFVKLGLRYICVLRDGRYAGMAHKKTFVKYVRDLEGHEHHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGQ2</accession>
    <name>A0ABR3ZGQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ureidoglycolate hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26340" checksum="1A8F503EAB544368" modified="2025-10-08" version="1">MRISDLIMTTKDADLDIDLGEIAYIPTTGVTKVFDVPVVDATSESIKGYGQIVDSDPKNFPIEIVQWPAQGTRPVDPNSGDQGGVTEGLFEFWWKGDTLYARNNAVGDSYLFAWSVLPEQAATTGPAKHPRDKVLVWRANYHPDGGQLFFPIDDKCNGFLVPLALPGDEVTPEKFVAFRCTGGKGLYIHPNIWHGAVVPLDDHSQILDRQGRVHARVSVDFVKEFGGYLSVPLEPTNGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGY0</accession>
    <name>A0ABR3ZGY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002782</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF18">
        <property type="entry name" value="NICOTINIC ACID TRANSPORTER TNA1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="74"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="530" mass="58821" checksum="C6381ABBEF18BB8C" modified="2025-10-08" version="1">MADNATRDVEHVDPDLPHEHDHDHDPIDEKTAAEAVKAAGGLRTVDAGLEADQVVLAMDKEREARILRKVDWRLVPLLSFLYLIGYVDRSNIGNAKIAGMADDLKLEGLMYNTALTLFFVPYGLFEVPSNIVLKLIRPSIWISVLLFSWGLVMTLMGIVKNAQGLYAARFFLGFAEAGFFPASTFLLTIWYKRYEVQRRMAVFYAAASLAGAFSGLLAFGIQHMKGVAGLDGWSWIFILEGIVPVLMSFVVWKILPDSPETASFLTNEEKEFIINRLALETGTGRGRVTNSDPIRWHHVVEGFSDWRIWCGVICFWVCTIGTYGFSSTAPTIILQMGYESADAQLMTVPIYVFALILVIVFAWFSDKMQQRTPFIMAGFALASVGLIAELAIPHPRMTGVSYFFLYLIAGGLFAPFMCVVCLIGNNLAPSSKRAVGMAVLISVGNLGGICGSNIFLAKQAPRYQVGYGTCLGICLAGIVAAYVLRVAYDRENKRRDALVESHTEEELRAQYTEQQLLDLGDQSVYFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHF2</accession>
    <name>A0ABR3ZHF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">LOS1</name>
        <name evidence="15" type="ORF">Sste5346_002889</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <text evidence="11">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045546">
        <property type="entry name" value="Exportin-T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19282">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6 11" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="13">
        <location>
            <begin position="108"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-T C-terminal" evidence="14">
        <location>
            <begin position="347"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="928"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="931"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF19282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1899490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1076" mass="120047" checksum="9033DB2A7FB76CF7" modified="2025-10-08" version="1">MDSQVSQQIEKAIEIAWSPTSDAALKGQAFDYLHQLRSDPQAWQMCAALFTRSPRTSEVVRLVSLEIVNNAVQTQALDGNSLSFLKNTLLEYIQRTYGSGDPDPQVDPPALQNKLTQTLTYLFVYSYQEGWETFIDDFLALTTSPNGGGQRDNIAGVILYLRMLGSVHDEIADVMLARQSADVKRNNNLKDLVRDRDMHKIARSWQELLMQYGNRNDHILEMTLKIMGKWVSWIDISLVINQEMLSLLFPLIGRSNPNSGEDKVRDAAIDTVTEVVAKKMKPSDKIEMISFLNLRDVVSQLVASPPLNDYQKTPKYDTDLAEAVAKLVNTVVSDIVRVLDDSSVESDARARAEPLLHEFLPLLLRFFSDEYDEVCSTVIPALTDLLTFLRKVPNLPPAYRDMLAPILNAVVGKMRYDETSNWGNKDEQTDEVEFQELRKWLQNLQKSVAAVDQDLYVDVLSNLIANAFQTLDQQGSNMDWRDLDLALHELDLFGELTLPNQGLTAKSKPSAAASERMVALMRKMMESGIADFQHPAVLLQYMEICNRYCSFFESHHEYIPRALENFVRLTHHEHPRIRIRSWYLFHRVVKQLRSQVGNVAETIIQSISDLLPIRAEVPNDEADDDMSSDESDHSADALFNGQLYLFEAIGCVSSTNATPVEKQALYARSVMDPLFSDMERNLPRAKSGDTQAILQIHHIIMALGTLAYGFSDYQVSPGAGSSSSNNNKPPPDEAISREFSRAAEAILIALGELNSNSEIRAACRSAFSRLLGVMGVAVLPQLPQWIEGLLSQTSSKDEMAFFLRLLEQVVYNFKGQIYNVLNMLLTPLLQRVLGGLSEPISGTDDEIQLAELRREYLTFLQIILTNQLEGVLISEANQGFFETMISSVTALAKLIGHSNLIGSRLAFSVLARMTSVWGGPDVAVIQAPPGSTNNANNNPSSKSATSTSNNSANNNNNNSNNSNNNGEHYPALGGPPAPSIPGFDSFVIDRFHSTCWDVLRDPQFRPGKDAQSRQVLNEIAGLEQTIYVKTGDVFIQHLQSTLLPQLGGGAEFVQNLTTATDRRTFALYLQNLRKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK94</accession>
    <name>A0ABR3ZK94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xanthan lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002196</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498:SF1">
        <property type="entry name" value="COB--COM HETERODISULFIDE REDUCTASE IRON-SULFUR SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="FERREDOXIN:COB-COM HETERODISULFIDE REDUCTASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12831">
        <property type="entry name" value="FAD_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="59558" checksum="4BB93E247708F531" modified="2025-10-08" version="1">MSTYDLVVYGSTSAAVAAAIQAARLGRSVALVAPHAHIGGIQIEGLGGSDIDNQAEFQNSTTLGGLNFELHERISAVYGGERPDRLKKTVAEKLRDPDVWRFESRVAEAVISAWLAEYPDHITIIYSALAEGAGAVQKNDAGVVESIRLVNGDVVNGRVFLEASYEGDLLAAAGVSTTHGREAQSVYGESLAGVRGTTPYRQIDVPVDPYVTPGKPESGLLYGISSEPFGNPGDGDNHLQSYSFRVPLTDDPANRFEALGGAPPPPGYVASRYELHRRFLRSGGFMYSPTCKVPRRKTDLIGSEAPLATDLLGLNDEWPVATYARRNEILEEATTFTQGLLWFFANDGSVPEAHRSKWAQFGYCRDEFPDNAHFPRQLYIRDARRMVSDYIITEETATEGGAPEVEDPVALAYWPTDTHSVRRILRDGQPHNEGFVFKDGHRWRPFGIAYRALVPRRAEASNILSATCPSASHVGYGAVRLEHQFYAIGQACANAADFALSQKVAVQDVPYSELRTRLEEQGVKVDVTTVGKPTFPELAAVRMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKV4</accession>
    <name>A0ABR3ZKV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34390" checksum="DE908BB37F6D318C" modified="2025-10-08" version="1">MSSTVRSLRRALPRLPFTSMVMRPTTTAALGPAPGELFRRRPQSMFAFVTQANNKQQQVLPEFSLKDKVVVVSGAARGLGLVQAEALLEAGAKVHALDRLPEPSPDFARVAEKAKGLGVSLTYHRIDVREEEKLNELIKSIADEHGCIDGLVAAAGIQQETPALEYTGADVDKMMATNVTGVFLTAQAVARQMVRLGQKKGSMALIASMSGTVANRGLICPAYNASKAAVIQLGRNLASEWGEHGIRVNTISPGYIVTAMTEALFDKYPERRSDWAKGNMLGRLSTPEEYRGAAVFLLSDASSFMTGSDLRIDGGHCAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL06</accession>
    <name>A0ABR3ZL06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466:SF1">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="62636" checksum="1D1B0607751D871F" modified="2025-10-08" version="1">MASPSHNRRRSKNHSREASLDISFENTVQNKSLQPCDLNGFMDYLYYVERRAENLQFFLWYCDYVERWSRLPSQQRQMAPVWGPAEAAEAAQEDAKAAASAANASTTETSIHPPPPTASINGKQHIPHSRGPSASSSRSHSRHNLSIDTSNTGYPYGANGQYKPRTNSVASTATAASVSSMASVSSQLSTSSRLAASIHQRSDNAKLTNILTILENLPEATEPISAVEAPKSKHTPSRYGEISPGMILPNGGSVASFDFQQQQPFHDELSRVVRHYVAANGERPLPDLFPPERLACLRAAKRTTHPSALLPAFLAAESALREQSFPMFVRDWCVGNIEKSSPRLVFVKIMALVMFLVGVALDIVLILLVGGKEKHAPPGMLNMANCLPRIACLAFWWPALAVLLAAWRKIDLLLHFRAQRLLRPWEIDDDDGDDEEAGSPMSAYSLDLEKGMAGKSGGKSYQRGHRHQASTSSTSSRIDPLRKVSLQALGPRNDPESEPWARRQRRTPFYRRLSAELWPASTGLGSRTVAVQHTGVRSMQNRAVWGAVLWAGLASATLTVISLFIPSPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL56</accession>
    <name>A0ABR3ZL56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="596" mass="68007" checksum="52C251B4A36A52D0" modified="2025-10-08" version="1">MPDITLLTVNGDEYEIDDAGDLDYSRLASLWEPEPDPFSPLGGVTDKIHTTAACEAAIRGEELPTWDLTEMSYALQICVLRGTRHHDGYATELHDYVADGLPSAGRVSVPEAAFHRAQNARAIMSNRIPDIDIETEFNNEYPYCIWYPDVASEETYRQLVQRYPTMRYHVGRACAVAGYDKLYMDLDLLPDISIAEEARDSIVRNTDPENTGSRIIFDHIVAQPVRWQVMNDYTRHVELDNPQVARYGLNGDTAVVSTLMMRRDYNVLRHETSRFTLNVKDVGSTLQSPYYHAGDEQAPSYFNITEDWTVCIKDVRRFEQHSWHSQSDMLHLLSSPLPHDLPWGSKDLLILMAAYNGDVDRYARLRRPYSLHVSQAETSCICRGIYHSTAFAAWWAGQEEGMRRYASSIHARFIMVNDLSRITEETVDADLPRQIWYPTFALPATYIELARRKPSIRYVAARALVMADYMEVWDEMVNNNWVEPYFELLDTARRSHNPHYLQSLEKIMAEKGLEESRLERKYGCEPLTWTGKAMHGQVAVPTVDSVLWMEPTPFYDGFGVDASEAELYMAAASSKGHTEKMDAEGVAHEIGIVFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE2</accession>
    <name>A0ABR3ZLE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11 12">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 11 12">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_002056</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11 12">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 12">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 11 12"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11 12" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342773" description="Endo-1,4-beta-xylanase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="14">
        <location>
            <begin position="32"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="231" mass="24788" checksum="7F925ED60CCA6B41" modified="2025-10-08" version="1">MAQPTVISLLLVALFAVPGVLAAAVFQPRDVATADSVDTTAESFYSSFWNDGTAKVKYNNGPNGQYTVNWSGNKGNFVAGKGWNPGGPRAVNYSGTFEPNGNAYLSIYGWTTSPLVEYYIVESYGTHKPCSSPTDDAEQKGNVTVDGSVYEIWTKMRKNKPSIQGTATFPQFWSIRTDKRVGGTVHTDEHFKAFTAGGLKMGRHSYMIVATEGQDSNGTASITVGVGPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLT6</accession>
    <name>A0ABR3ZLT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002112</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="660" mass="72312" checksum="354583F2D495EE07" modified="2025-10-08" version="1">MSTSQPSFLLPQNRKLRHLRGIYLRNLTFTQPRKYSIDDASVGPGGLASSADRGKKRASLRKALHHSRSSDDLLADSNGSAHTRNRSATLSGANALARQHILEQALDSSTADAFFSLHNDGADEPIYVSEVEERATNFNFRFFDLIDLDPFLSRSSQLTVKVWVRRAPSATTTSSTTSSTTSSPSSFPPSWSLLLEDDVDLRFLGCIGSLQNIHFPPNALVFHLLDGIYMAGVPQNRLVAPAGGARSNLIGVPPLPTSSYNALMRLANLENSLQDCLATQDKLAQQIEQVMADEASRVEDSQDESSAALLLPEAEARCRRALKGLAHRRRLTDAARKKRADLSESLDIRRAAIAAGRDLQQRAWADVEHANQKLASSRATAQRTRDDIRGQRRRVCEDLIRIYNISPARGVDEPLAFQICGMPLPNTVYSPMVEKSSGGRAEDTLSAALGFVAVLVNSLQTYLGVALPYRITAYGSRSSVRDDISKSIPDAQREFPLYMPRGGLNAQYRFDYAWFLLNKNIETLCHAQGLKVVDIRHTLPNLQYLLYVCSAGTEDLPERKKGGVRGLWQGHIQRHSVGGTDEEPNYKGERHDSRKDAAVVTTRGLLPTTTRTTTRATNNTNMATTTANNVPSVPAVAVAAPSSVASSPASTLHLPFDEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMH7</accession>
    <name>A0ABR3ZMH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipin Ned1</fullName>
            <ecNumber evidence="4">3.1.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ned1</name>
        <name evidence="4" type="ORF">Sste5346_001613</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.4" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057124">
        <property type="entry name" value="Ned1-like_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24565">
        <property type="entry name" value="Ned1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="3">
        <location>
            <begin position="452"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="659"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="691"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="756"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="834"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="883" mass="97565" checksum="402B346BAAD7A774" modified="2025-10-08" version="1">MQYVRNLSDSVSTAWNSINPATLSGAIDVIVVEQEDGTLMCSPFHVRFGKFSLLRPYEKKVEFKVNGARQDYSMKLGEGGEAFFVFETTDDIPQSMQTSPISSPASSPSLGPQTPPSGAAEVTAMPSLQEPSLLALDLESGKPRSATLTSHTVPKGIMHSSTTQQKNGLLTPLSASPEIYAGRPRSGDWSSFAQRSQSDDILRQAARQPSLTGNESVRAESVDREKDNGSPRLSDRSHSPPPLAPAEAIERAISLSKELESVNIPSRVTESGDLMLDMTGFKNSEEEALRAEVLARRVLSNELQGNYDVGALFGMDEQGNLWIYSSEEAKEAAMRRVMESSSMNRNPAVAIDAASDPGYHSDDSANSAPQLLPSHRRSESDAGQIGQTTPPSSPGPMTAVGDPNRNYAKTLRLTSDQLKALDLQSGENTMSFTVNRSTCSAKMYLWKCNVPVVISDIDGTITKSDALGHVLNMIGRDWTHAGVAKLYSDIAANGYNIMYLTSRSVGQADTTRTYLAGIVQNGYRLPRGPTILSPDRTMAALRREIYLRKPEVFKMATLRDIRNLYGTQTHPFYAGFGNRLTDQISYRTVDVPRNRIFTINANAEVSLDLLSLNMLKLTYVNITEVVDHYFPPISTLVKGGGEEFTDFRYWRDQPLEMDEFSDSESDDDINNHRHHRGRPQLNRLDSRMTYDEDDEEEDDEEYDDDEYDDDEDNGEMGDSYISRNSMDDYGEGSVLSGDFEGEGNDRMMHSVMTAGEGEEEDEEEFDDEEEEEEDDEEDEHIGGDQTVQKIPIASISPDQPLPTTETAEEEEEDDEEEEEPQPERASNTSKRHLSVASASDNNNNNNNNKLPSSSSSSAAEDVDAEVITGVRDLVIDRPTPKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMS7</accession>
    <name>A0ABR3ZMS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192:SF2">
        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="168" mass="18488" checksum="D6F10642877F4266" modified="2025-10-08" version="1">MSEDHRGTPEAPGRVATLIERSFWESLTDHHDSASDKVWGVAYRIDAAHAAEVREYLDIREINGYTIHYTPFYPAAKGAAAFRTMAYIGTPENPQFTGPQDVQKLAEHIFRSTGPSGPNRDYLWGLETALNELSPESGDEHVSDLSTRVRALAEAEANAETATAPSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPT5</accession>
    <name>A0ABR3ZPT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00322">
        <property type="entry name" value="FNR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052128">
        <property type="entry name" value="Oxidoreductase_NAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505:SF1">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="14"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="35243" checksum="91B84F43AFD9EC32" modified="2025-10-08" version="1">MAETKESHEERTAHEPREAALHSVILSEITLVGSLVRLLRLQVPDGAPDIHFLPGQWVDAFCPGIAKAGGFTITSSPSKAVTSTDDRYIELAIKKSPENPAAAWLWQDADEVLGQTLRIRVGGSFVFPPPGAPASFATDRSARVVFVAGGVGINPLISMASHLGELNAAANDESEEGTGGPEVVFLYSVQADPEAAVKENEDGNDDDNDGNNEADRIPFLQRLASLFSREAVRGQLKVFLTGRGSSNGGGNDVLSCNEEDVPCLRRRITTADLDKAVLGDGSRSSGQNLDNVYVYVCGVPTMTDVFVEYLTGKDGPGLSTQQVLCEKWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ84</accession>
    <name>A0ABR3ZQ84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine resistance protein</fullName>
            <ecNumber evidence="6">4.1.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPE2</name>
        <name evidence="6" type="ORF">Sste5346_001387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic AdoMetDC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048283">
        <property type="entry name" value="AdoMetDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018166">
        <property type="entry name" value="S-AdoMet_deCO2ase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01336">
        <property type="entry name" value="ADOMETDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="437"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="605" mass="65108" checksum="FE3EFF1CEDF45475" modified="2025-10-08" version="1">MVALDIPNGCTLSPSLATPHLVGTPHLHINHDVAADLDSSNAFEGPEKLLEVWFAPSPKALAPSVKENGLKSVPADVWVEMLDLVNCKILSVIHSETVDAYLLSESSMFVFPHKIILKTCGTTTLLLGLHRMLRIAATVAGFPFHNAASTNDIRVAATPYRVFYSRKNFLFPDRQQGPHRSWKQEVKYLDDMFEGGSAYMVGKMNGDHWYLYITSPTFNPTPPQTPVDDDGNAVPGSPAFRSNKIPTGILTAPAPVDSSASTTAADEKDATDETLEILMTDLDPENAKQFYLSNASAVAHDRLLSQTNSALLKAAAASKQQKNGHSHQQQDSHMSDSTYSVLDSEDLFDVDDIAQDGANGNKSGNGGASSGGSLTPLSEHLDSVDMEALTTEGHALGTVVSDSCGLSDVYPQSVYPDARIDAYMFSPCGFSANGVIPAPPADEQPAANGEVPETTETASVSTSDSSPASAQGNHYFTVHVTPEPNCSFASFETNVPGGQKGRQTADIVKHVVDIFRPGRFSVTLFEAKGKAASATGASSKDQYFLANDNAVKSNKVASPGKRLEQIPGYRRIDRIVHDFEDYDLVFRFYERDGFVSNGEARVGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQA7</accession>
    <name>A0ABR3ZQA7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="246" mass="26025" checksum="E4DD63B067C22DA8" modified="2025-10-08" version="1">MRMTTSTFPPSSSSPRRPQQASHRTPTRPPPVVISPSSSSVPSSSPPRSSRPRHPPSTTNSTTAASGRMRISPAAARAGMVMTSPSSSSSSSSSSSRSLRGSPSGSLSSRSLNPIGSTHINPPPTTSSSRPTISRPRPLILASTLVQSPNNNTSTPRRSINPNIAPRAAPKPPRTRPVPISTTTSSTSSPLRKKNPSTLNIPVRKQDKDKPTIANRMVAALRTPTTKKSIESFACVDSRRVEAEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQT0</accession>
    <name>A0ABR3ZQT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001488</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="50"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="452"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="531"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="454"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="967" mass="106553" checksum="28FEF701DADE4E46" modified="2025-10-08" version="1">MMALSPPLTPGRQPNLPSTTTPSQPSTQQGPTVLTFALNHRPRATRASVPKVRTGKRHVKCDEAKPSCSRCIKWQGFCEGYDQAAESASIEAAAAAASQLPATTTTAPTTAPARPRTTATPRTTPTTTPAGTPPGATKTPRNRNPATTCPNVNPNAAAKTARAPSTTSSSSATQGSRRTTPSSDVSASEYVHTTTAPPHTTPARTATPSIKREPDDDTPRAHYGDHPIFVGDDDSNASVIFMPREPIYVQTQEQRQFKREYDDEDDVEAEYYTHGEYAPDFVLAQRNTSTQPYFDLSLINGGTSSSFPLEPNYNSVMFASQWEKAYFDSWLTLAPNLGGGWFPSHLWTSTIPQLCRDEPAVRFAAIAIGAMAQAMSPALLGKSYHHMLGGNTTADDQSSQPGQPGQLGADGTIAAFPAAESVEASRVVPHYRNALTYYGHALRLLRLGGGGGTATSENNNGNQPQQAHTGNDPETPPSSEKERAAVLSCLLFVCFEALQGNREDALNHITHGLQIVDQFVARNLPPRALSEAQAYSPPDEASLLAGTDSDAEWQRRRQRQRQRDRQLGLLAAKQGEAPASTENPESHHRTTLSEDRPSDSLTRVLTRSPAPYVLEDEVMQVFRRLDFQAWSLGVFRLRRTRPADIKFQALDALNPATIPARFDSLDDARRWWDFVQHWILQFPRYMVAALQRYMDENPDAAERATAAGRMLDICDVPGAREIQREYLECLKRWYDAFYPLYEATHRQGGHPTYGHGGDPAAAAAAEAAYFRAASLKIPYILAWIGVSSLVYSDYEAMYQLTPQFRELNRLAALILPKQPRYAWSPFGGGASSIFGPPPGGATGGSVGSDGVRGDLFTMDNGPTMALFVVSCKCRVEAVRDESIRLLAAYPRRDGFWDSKILWAIADWNRVIEAENETEGSLYEQWLRLRQREAIFDETKPEVQMTAWVKNKESGKFEKLTQTVRWDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRR7</accession>
    <name>A0ABR3ZRR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17289" checksum="1A2E93A47C495956" modified="2025-10-08" version="1">MSATRATFTDQKETFEAAISGFFSGKPEETEAYLATICHPSFRLTADNEAMDFPGFVKHMTWLRENLPPNAISLTITQFLVDGNQRADRHSSTTKMPDGTVRGAETYLFAEVADDGRLLWVKEHVMRLGVQQPDGTFKKDDVVPSKTTGDAKEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRS4</accession>
    <name>A0ABR3ZRS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">8-oxo-dGTP diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PCD1</name>
        <name evidence="9" type="ORF">Sste5346_000685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF24">
        <property type="entry name" value="PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="128"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="474" mass="52095" checksum="AAC3DD5666693854" modified="2025-10-08" version="1">MTTSSAGRLAVAEDQATDSTPIDNANGTTSTAETNDTNPSLTPAEVDDIAASIHEATSEPITAPGPESDLDKNEEDDDDAPRASIGDDSYYWDPSTMAPLNARSATAIARLRAFRPPPFPLWDRLPVSRRAAVLVLLYADRRGDLRVVLTMRAASLRNYSGHAAFPGGKADSIEETAEQIARREAWEEIGLPLDDSKLPRPFRIEHLCDLPYNLAKTELVVRPCIALLHAGEGDADAADKKNGSVPNNNGEDEVTPDEALIPKLDAKEVAAVFSAPFHNFLLPVDEVSKDDGMPLALSQIKPKNDAPQRRPKLPPGPWYEGSWIHWHEEPWRMHFFYVPVVGQRVAKPRKRVRDAKDDADSKKKPTAAVVAADQAVGTPPAVITDKEDEQKDQDEPVIDEIEDSPGRYKVWGMTARIIVDAAKLAYGETPTFEHNSHFGDERIIEGLEKMGRLGEKKKVGSELTHEDLKEASKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSJ3</accession>
    <name>A0ABR3ZSJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
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                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
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    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <sequence length="75" mass="7931" checksum="4278D5E300AA7AF4" modified="2025-10-08" version="1">MSLQKMIPLGLAVVFGVVNGIYVFKPYLEGKDEVGKLDLPKTNSASASSASKTPEAPQQPKTATQPAAVESLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Sporothrix stenoceras</name>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <strain evidence="10 11">CMW 5346</strain>
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        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
    <sequence length="2356" mass="256061" checksum="B02C6290C261D986" modified="2025-10-08" version="1">MATRNSSEVIDLTKDDDMEAEQMEKLRNNHPPRIPPLSRTHNPVQLFATIYREGDAVSASTSFSSPTSMRGPSSADSQQPARPVQTSPMATALDFGLFFGRQASVNPPVNGVVSNSQQASSAAQSNSASPPARPGSQQASDQRARLDLRPEPLYGRSSPNFHRPPSGQASSPRSFAQPPQSAQPSASSPSGSRPAAPGSSDYMRAPTTQAQPARSTSGNTPTTTAGQSNQASPNLSSQSWMGRQSPVFGNQQASTASASARASPHQSFTARASFGHSTPPYQRQTSSSQSFMETQQHQHRLQQQRQQLEDQRQYDQHRQRILDQQRRQDQQRQLEMEEQRRQQAMQRKIEEEQKRQKESDQRQQDEQRQQRQEEQQRLQRQHLAQAHAQAQAHQAQTQQQHQHQQNQHQQNQQRNGLHHSASTGHLSSYSLNAGTRSPAQHSPQHSPHMHPSSTSAPLWSSTSTPLATAGGPPSSLQPSQTHPLPNPTAYRSASAGGHTWQTNLQQFHTPHRRNSPLIRNSPPSQTLPPVQTKSPPHPYGSTQVRQHLPNGRPSPGQESSSTMAARNTSGTQQQQQQTQTGSHQPLSAFSLRKSPPRDIQTQQAQSHPGRSPPDPSPPSKQGPSPGQPSTTAQTSQTHAPARPVEPLWSGRSMVANRPAPTGEALSSRQQPVALSSSTAGAGARTTWAPSPTLVASSSPVSISSGSSSPRPGSAAATTSTNPNSGDRNINNLNLLRPRFSAQIELLPDRLRLGTGGPYSSQPISNSASSGNSPMPLSPSSVSSFPDSGARRQDKTAPHGNSTRDKHAQSNLHSNVALHDETLPDAPATTLQDVTRQDAALQDKLLQAEARRATENLALTPQAREAEIRRAEAQQVEVLQAAALRADALQAEALLAEARRAEAMQAAEAQRVDAMKIDAIQAEVLRTGVASPNRTLSANTTPTKNGVSVTGSDVHPIPSPAHTPKAQQDWTVAKIMTSLETYLDALLVDHGRDVEYAIDVSKPQSQTVFSSFDDFADLPVQNIDASDATTDRVLLRGKLHRDNQKRPETRTIHARVLPLKTPGEAVPKYRFHHVEIAKNILSPNTPLKFIPHLRDFEDNSEEKRRHDQWIEELESMERKSGFDSSKLFQKGDTTRKSEFTKLLSDYLDHWIARLGIDNCSKTSLIRYMANESQNDQTITPQQKNSLLSSCGEDSATPRAAVVASMLTEAFNRVFASRDVTLYDVLKQDEAVENVFDPKKATKNKDQDKEPSLEQIQQYLGTYTSLKCMICNTHSCEHGEFDAENVRRCFSIDDLGGKLWKHVERRRDRQVRELGQLRAHQQKALGATSGNSNMGGSSNSGEFGGSSKFGASSITPSANSPPCRNKCYRSYDVGDAAFTTREWTENETNLLRSFHLTFANSTGKVPCALCPMMGRHCWEIYRRMKELGLPIALRPDTPSQAADPPTVTVKPVTWYDRHRKVLNGDWSDHTHTHMYALREQREPCNHDGPCTSARGCPCVEAKLLCERFCRCTAECCAFKFTGCACHGSGKTCYQRQKEGKPCICVQLNRECDPVLCGGCGARERADPENRDNDELHATGCQNVSLQRGKSKAVVLGQSQLQGCGYGLFTAEDIGADEFIIEYIGELITHDEGVRREARRGDFFDQGANASYLFTLLEQDGIWVDAAIYGNLSRYINHASESDKRGCNITPKILYVNGEFRIRFAAMRDIKAGEELFFNYGENFPNLTKKLLEDKASASDDEAAASTAKRSRGGAAQRSAGSNSNSNSNNRRKTSQQTMRSRAPTKSVQSGPSNSRNGSNANANASSSSKNNRGANSSSLPRRPRPKGGARKEAPPPHRADTDDLSADDDDGDVDNDDDDDVDHMDIDGGSGAPQRSSARSRSATKSTSLKRKRRPIIDDDDGDDESDGGLKDKIESDDEKPADRSRRAARSSRRRTTANAATTAPSTAAPAAPVTPSVTETADLPETPRRLRARLNAQQVSDAPQQANGLDSSSNDRGHSHDAHDAHDADEDDDVPIAMVKSDIRDSPRASKRRAATCLSNNAAATYADGDNDTDQQPLRKRPRIGSRRGDAAASASAADHHTDSDNMVVDSDDSIPTRSLRQRRSRQRQRVTELSAADLSDQHAGSDGGDGDSAAASAVVALGTTDDDQGSVFSSHQFCGRSQNSANGAVDGTTTTTSTTAPTKTTSSMTTRRRNIVPDSDDDLDASQNSTRASRSGGRNSSRPSSSSQPIPAAAATSRVGTPLSQPHTPKVGDKHSSIHDKVDATAGGGGSISRSSSSRRNLRRGDDSAAAARPGSSGSASVNPNSQAQQQQQQQHTTPVNSRVRSGGEDDSGGSSVDRSQRKRQMPARYRTEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT65</accession>
    <name>A0ABR3ZT65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Partial AB-hydrolase lipase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="3">
        <location>
            <begin position="311"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="804" mass="90503" checksum="7A488F7A33678284" modified="2025-10-08" version="1">MGSDNPRPDVEPPAQQRQYGPDNDDTYDAHSPLLSDETLAQTAVEFVKQSEKLSLQKPEDGPPDQPRDMAVEARFVTPQDPVIVTTAGNRLPPVPLSEAHKLNILKDELQGGAQVQDEKAAYDTAKTAEASSPKRSPDEPGPPLSSQKLLDIGKQERQKKKKKTKKLGSPMQKSAEGTLQRAMPPSHTNPLFPPLPLYGPPSILRNLQSATFRVSSFCLSLSFLGVIVLGSLFTSIPGAFRRIACHLTFRDPDAHRPLFAEEKRRNHLRRDMDRNWRRQRRDSSEDPAGAGVGDVTYTPTAGGPDPLIPDVAHYARRVGLDVEAFEVQTEDGFIIDLWHIIDPNEDTPRLAEARKNRGPGLLFDETTADERAATEREMLNESRPKKPKFPVLLVHGLLQSAGAYCVSDDDSLAFYLCKSGYDVWLGNNRCGFQPRHAVLHPSDPRMWCWNIRQMGVFDLPALASRVLRETRFARLGLVCHSQGTTEALVALAKEQRPALGEALTVFCALAPAAYAGRLIGKMYFKFMRVISPAMFRIMFGIHSFIPLMMQVHPLLPGTLYGWLGYRVFSFLFEWSDTRWDRGLRNRMFQFAPVYVSAESMRWWLGREGFARHKCILATKEEWRREEAEAEENEASAVEDDTEENEENEDAAVNRLPGSTAWYDERAPPFALWVCGRDDLVDGHRLLKRFLPKPVFSALDQGQGSRSTTSGTLRSVREPHVRVVHAKVIPEYEHLDVIWAMDAVDQVFSEVREVLWKTCTVRDLCRMPRGCENVEAWEDPALKWKQEKAGENETGEKGDAEKSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTQ6</accession>
    <name>A0ABR3ZTQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E3 ubiquitin ligase complex SCF subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SCON3</name>
        <name evidence="7" type="ORF">Sste5346_000121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="6">
        <location>
            <begin position="9"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="5">
        <location>
            <begin position="120"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00045385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="170" mass="19623" checksum="E435CE3BF237AFFE" modified="2025-10-08" version="1">MPEEKSFDKIPLQSNDGSIITVDYDVAIRSALLSTMLEDLKSMGVEDLGPVPLPNVNEAVLRKVIEYCEHHRNDPLGTNEEETESRKKTTDIEEWDQKFMQVDQEMLFEIILAANYMDIKALLDVGCKTVANMIKGKSPEEIRKTFNITNDFTPEEEEQIRRENEWAEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUH8</accession>
    <name>A0ABR3ZUH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosine/serine/threonine protein phosphatase pps1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PPS1</name>
        <name evidence="6" type="ORF">Sste5346_000315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14516">
        <property type="entry name" value="DSP_fungal_PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053239">
        <property type="entry name" value="Dual_spec_PTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047949">
        <property type="entry name" value="PPS1_DSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="535"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="603"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="722" mass="79747" checksum="BC79B9EF1C7D9D95" modified="2025-10-08" version="1">MATIALTRPMPPHRASSGMSSLNPSINIDIDVLNNQTAQPHPQSAGPVPNKHIPVCPPGPPVASATPSPSPPPDEPSDHQQSLLFPPDQYPRSEDGELSIYTIDPTGVAAAVDYIARQPLPDPSLVFPWFHGLHPGNHMQQAFFSQRRRVMRKTPCCLRGLTIVKADGQLQVARLKGAIAPDEFLQLGTTSEFLDADPKEGFSVRNFQIQAAKTAMTSDIIVYGDDNAAVQKLAWNIAAAQQNWRDRQDLEGTALPIYNTFVCTSDFSVFEESYPHIVSADSEGRITGNVVDFFHQERTEMYAMTVASEISHNVWLGPTPEPNSEDEDAYDILIECSDLGHLNPRALRALAETGTPAGLKTYLDFPSSGTILPPTWSQTEADAILESCKWIYHLAHGTAPPSPSTSTSPMDFGISSVDDDGDVAMVGETEGSQADADHQPKKILIHCADGYTESTMLGLAYFSYSTGSPIHDAWLNLHTTKKRNFFAYPTDVALLTSLSPRLLCESPLCVEKDLDSVTAMVQNQPRWFSSLDGSFPSRVLDYMYLGNLNHANNPDLLRALGITQILSVGEMAMWRDGDLEAWGEENVCVVQGVQDNGIDPLTDEFERCLEFIQQGRKKGTATLVHCRVGVSRSATICIAEVMRSMKLSLPRAYCFVRARRLNVIIQPHLRFAYELLKWEEMLRQNQATDTSFGRGSNACVKRELEWGEIAREVALMNQPYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUR0</accession>
    <name>A0ABR3ZUR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial</fullName>
            <ecNumber evidence="3">3.1.3.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PTC5</name>
        <name evidence="3" type="ORF">Sste5346_000259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.43" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="253"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="671" mass="70992" checksum="73CB44F040C43296" modified="2025-10-08" version="1">MRRAAVRAFRTTSQHTVRGLLQQRTTRRSAALFLQSASHHNPHNTQHYQALNSQRVRCLSSTSFALAPQHRLSRNSKSSSSSSLPLPPTASGEPLHSSMHIRRLSVAVVSGLVGYGAYYAYQGQGAAGQSSLFSTKAAAAAAGAITSTTGASLAGGGTSTTGSSDAAQTTRNVLVIGANELSTGTLVGDGPISKMTDGSGRRVLEMLAPDQVTQRLRKNEESYGINRGKGVLRYDLVQLASNDPIEDDHAEKIVEVPTKSAAGSVVSSDSSDWMFWGVFDGHSGWTTSAKLRQALINYVARELNETYKAAPNETGPPADAIEGAIKVGFTRLDDDIVNQSAEKVLSQKSKTVAAELLAPALSGSCALLSFYDSKSKLLRVACTGDSRAVLGRRSASGKWTATPLSVDQTGSNPDEVARMRGLHPGEEHVIRNGRVLGGLEPTRAFGDASYKWTRDVSDRLRNSFFGRSQSPFMRTPPYVTAEPVVTTTKIEPENGDFIVMATDGLWEMLTNEEAVGLVGKWIESQAKAVGAGGNAGGSSTMDSAWSKVFGGGKKAGGALPVEAAVEGSTGKNGERTPIRLRQWGISPDDSDRFVVKDKNAATHLVRNALGGSNEEQVSALLTLPAPFSRRYRDDLTVQVIFFGDGAGPAAGGDIVVNQEATGPGSSVKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZVX3</accession>
    <name>A0ABR3ZVX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1909-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8408" checksum="6DF54DF6BEFE01DC" modified="2025-10-08" version="1">MGGGNGAKAAQKRERNAKDKAGAAKSQLKANEKALNIQCTVCKATFLSTTRENALNEHATNKHSKTIADCFPDFKAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZWN2</accession>
    <name>A0ABR3ZWN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Protein arg-6, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ARG6</name>
        <name evidence="20" type="ORF">Sste5346_000081</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 17">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">In the C-terminal section; belongs to the NAGSA dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">In the N-terminal section; belongs to the acetylglutamate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04252">
        <property type="entry name" value="AAK_NAGK-fArgBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23936">
        <property type="entry name" value="AGPR_C_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24149">
        <property type="entry name" value="AGPR_N_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04263">
        <property type="entry name" value="DUF619-NAGK-FABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058924">
        <property type="entry name" value="AGPR_dimerisation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041734">
        <property type="entry name" value="NAGK-fArgBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011241">
        <property type="entry name" value="NAGK/NAGSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF0">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22698">
        <property type="entry name" value="Semialdhyde_dhC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036440">
        <property type="entry name" value="ARG5-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 17" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="15 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16 17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12 17" id="KW-0521">NADP</keyword>
    <keyword evidence="9 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="19">
        <location>
            <begin position="360"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR036440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1903454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="943" mass="102842" checksum="8FA73082B6956854" modified="2025-10-08" version="1">MLSTVSGALRAGARSCVRSRPSSVSTAALRSHSSLSTKRSSLSALKAATASVTSSSQRRALSTSSTRQTDLSTRGLMIQALSSIGSKREAQQYLSHFTSVSSQKFAVIKVGGAILTDYLDELCASLAFLYHVGLYPVIVHGAGPQLNKLLEDAGIEPQFEEGIRVTDGPTLAVARKLFMEENLKFTQRLEDYGIHARPITSGVFYADYLNQEKWGFVGKVNRVATDVVEAAINNRFLPVLTSLAWTESGQLLNVNADVAAAELARALEPLKVVYLSEKGGLFDGEGGKISAINLDEEFDWYMSQAWCKFGTRLKIKEIKDLLDTLPRESSVAIIRPQDLHKELFTDSGAGTLIRRGTKLVSASDVTAFSDVEQLKEVLLRDRDGPNARQTVDTYVEFLRENPFRAYYDEQMNALAIAFPPSADHPFATLATLTISKSGWLGNVAENIFTAIRKDFPKLIWTVNENDENLTWFFDKADGSVARNGNVLFWYGVEDGDEIVQVMKDFSEHGRSMLGDANLEARLQRAAERAGSDGGAAAAVKAATNAAFQQSSPLQQQQARSFSTAARRPLSASSSFSTFSSSRFFSRRTTVAAFSTTRANRIDEDTTNPNPPLGKKNATNTRAARVALIGARGYTGQALIALLNAHPHLDLTHVSSRELAGQELKGYDKSAITYENLSPEDIREMESRNEVDCWVMALPNGVCKPYVDAIQEARRDSAGADKSVIVDLSADYRFDKSWTYGLPELVKRGEIQNASLISNPGCYATAAQLGIAPLLENLGGTPVIFGVSGYSGAGTKPSPKNDVEHLTNNLIPYSLTDHIHEREISNQLGYNVAFTPHVAVWFQGIHHTIHIPLKAAMTSRDIRQIYQDRYAGEKLVKVVGEAPLVKAISGKHGVEIGGFAVHSSGRHVVVCVTIDNLLKGAATQCLQNMNLALGYNEFEGIPVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGD5</accession>
    <name>A0ABR3YGD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_010450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000149">
        <property type="protein sequence ID" value="KAL1887090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052965">
        <property type="entry name" value="Pigment-catalase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694">
        <property type="entry name" value="DESICCATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694:SF26">
        <property type="entry name" value="OS05G0151100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="296" mass="30797" checksum="C3C53EAD00C39A81" modified="2025-10-08" version="1">MKSYAVAALAATAAYAAPVQNAKRAVTDADILNYALTLEHLEATFYKEGLQNYTQADFVAAGFADPFYANLMEVAKDEATHVSFLTSALSAAGATPVAACTYGFPATDAKSFVALASVLEGVGVSAYLGAAASIADKDYLTAAGSILTVESRHNAYIRAALTESPFPQPFDDPLSLNEVYTLAAPFFVSCPSTNTALPVKAFPTLSVTTAGPLKTNETITLAVDTTTYMPPAGTPVFAAFVTVTGPIYVEVTSVYAGFSVMVPEGVEGQSYVVLTMSNTSVSDDNTLAGPAIIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH16</accession>
    <name>A0ABR3YH16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010212</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="45"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="540" mass="59035" checksum="954137CE79C968DC" modified="2025-10-08" version="1">MDEKKETVMMASPQNADDLEKVDSQANAEVNDIHGHLNRGLKERHVQFIAIGGTIGVGLFVGIGSALATGGPLSLFLGYLFTSIAIWAMMQGVGEMASLLPLPGMIAQSCTRFVDPALGFSVGWNQWYNCAIAIAAETAGAVLLVQFWTDINPAAWISIILVIVFALNFCAVAIYGEAEFFFASLKIITIIGLLILGLVLDLGGGPSHDRIGFRYWVHPGAMNEYIATGNTGRFLGLFSTLISAAYAFGGAEQVAVAAGETHNPTRAIPKAIRRVLWRLVMFYVLGAFFVGLLVPSTDPNLVNGSGVKASPWVIAIQSAGIPVLPHLINAVLITSAASSANANLYTGSRYLFAMAQQRQAPQFLLQCNRQGVPYYCVGITAVFGLLAYMTVSSTSSNVFHWLSGLVATSYLLTWTCLCYAYTRFRRALVAQGIERTSLPFKGTFQPYTAWFGFTFFVIVLLFNGFAVFTHGNWNAQNFVSAYVGIPIFTVFFLFWKFTKKTKMVPIEEMDLYTGRVAGDERDDPEHKTKTKLQKIFSKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHE3</accession>
    <name>A0ABR3YHE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Na+/H+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CNH1</name>
        <name evidence="15" type="ORF">Sste5346_010041</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fungal Na(+)/H(+) exchanger family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013928">
        <property type="entry name" value="Cation/H_antiporter_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF4">
        <property type="entry name" value="NA(+)_H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08619">
        <property type="entry name" value="Nha1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="404"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="13">
        <location>
            <begin position="26"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Alkali metal cation/H+ antiporter Nha1 C-terminal" evidence="14">
        <location>
            <begin position="458"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="453"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="763"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="854"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="696"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="766"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="909"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="972"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="987"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1887701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1041" mass="114937" checksum="606C3BD2F73E8C5F" modified="2025-10-08" version="1">MAWGHLSITKPHLVYIILGGFTSLFMLCSSIIKERIYIGEATVATLCGLIFGPHAADLIDPASWGSVDIVTIEFSRIVLVVQCFAVGVELPKFYMERHWKSVIFLLVPVMTFGWLITSLFVWWMIPPLDWLDSLVIAACVTATDPVLASSVVGKGKFAKRVPKHLRDLLSAESGCNDGMAFPFIYLSLYLIQDHRDAGEVSFHWIVYTILYECIFGAIYGFLIGYIARHGIKFAERHDLIDRESFLVFYFVLALFCAGSGSILGVDDLLVGFSCGVGFSNDGWFGHKTEESHVSNVIDLLLNLTYFVYLGTIIPWEMFNDTSIGLSAWRLTIIAIFVILFRRIPIMLALKPFIPDIKTWREALFAGHFGPIGVGAIFVAIMARAELESDSPVPLSELPPPDSPHYTLLTLVWPITTFLVVSSIIVHGSSIAVFTLGKRINTLTITMSYTTAPEDGPSWMNRLPRISSQSRSQARTMSDTDMDELKMPSVPPGTLLPVGIPGQFLRRIKDEEGTSKQGSRASSRASRRRRKKWDDGIGPGGPISQSAIFPRRPANDAPLSSPPLQSEVSGADDAEEQPSQGSGQTIVAEEEGRFEGGDEEKRGRHERRRSSDDADGSVSPTSAPRLNVYDEGDNIIIETDQGEVVAVEPTQSHNLPSEADVEKLKEKLTPEALKAEAGTSGWSYDSIKKKIGNWKNDEIQKRKEKQKDTRRHEPARAYQFGNTIIVEDEDGEVVKTYELPPQRGEGGTSDMVSQSLKYMGMGGLIRPTEKAKEQEEENAKGSDNDVDPISRVSSKPAMPSWINFGRTTAGEPSAQRQRKKSVAEVQQEEDDRHIRFTIGGVGQRMTKEGFIKQMQQLDQSTRREVVDKSSASHTVKTLAKQDLPPPEIVVSRPEGRGRAGSSAVAGPHRSGKEVDGNDGRGDDDDSSPRSSTSHLEIASSSRRGRTVAGPSDDTDDMPETAVERRRRLAVLETVDDGDDDEDSDDGNDETKETPAERRRREAALGMSSHQAEDSDSDDDDTPRVPPARRGIRFADTPARRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHG0</accession>
    <name>A0ABR3YHG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar sorting protein Vps3844 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053065">
        <property type="entry name" value="Archenteron_Induction-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024382">
        <property type="entry name" value="Vps3844_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853:SF1">
        <property type="entry name" value="DUF3844 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12955">
        <property type="entry name" value="Vps3844_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163621" description="Vacuolar sorting protein Vps3844 C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting protein Vps3844 C-terminal" evidence="3">
        <location>
            <begin position="315"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="45604" checksum="008FDD6ACDBEC6DA" modified="2025-10-08" version="1">MKFLAGLAVAASLASSAAAAAASAPVYLLRSKSTSSSSPSTPSTSPNLPRQIARQILLQRLDANDGSSFFDTLPRDFDPETALDLIEQFGNKATPALFVDGTDSSASSQPRELLIVVQGTKPEHVAALEAALPKENNKPAFSVADPPSEAANTRLFVDELAGEGIVAHTTTSVADAVADGAPATWANGVFVGLYDVKKDTKAVDTLVSALSQIVALAESGAADVALLLLPESSRFAQWKQWASNKGLKPANARILPPKARPANSELRVRKADSEMVIEEFGVQEKGEEGAEGTSSIVPPHTFIAAANPAANIPGCFQSFNACVAQTNNCSEHGKCIDKFAVNNGKGGGASSSKSQEGSCFVCHCFKSLNRPEDSPGGLSTTQWAGNMCQKQDVSVPFWLITGFTITIVGAVSFAIGLLFSVGEEKLPGVIGAGVSRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI23</accession>
    <name>A0ABR3YI23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pal1 cell morphology protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000106">
        <property type="protein sequence ID" value="KAL1887867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF2">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="58790" checksum="9B181BBFBBDC6110" modified="2025-10-08" version="1">MSDFLSDQSADVRTSHLSSNNPFRRTVSPSIPSPTSPFLDPTPSTTSNGRPVSRNPFLDPANDKPASPSNGDLLISLDDMATRPAARSSIDDIFTSLKVDDKAMSAISNPNTSVPTSSGEPLKKPTEGGRPPRPSGGPTGPPGSRPTRGGRGGPPPPRSKNAPPRPSPPGQHRPSQSQEEAAKSKAGAIGIAKGEPAGASSSSRRPSQSTRARRNSESSIAPDDKTLSRGEKVLRDLRKREQEQRERGTTKPHRRNDIIDQLDASSIFGNVFHHDGPFDALNPHRNRKGSRRAPMQAFPKDSLNNSIGGSGPLNKRPDHREFMGQGEDEAFREFSNNHQPPPSGKIAPIGVFDPLQRGTALHGDQSLGLGTSTFLEGTPAARTTIQRREAERAQDIQDNPLQRKKSLAQRFRSINRGPREPHPTRAFSTDGGPASAGATTGRYNNETNPFDEFDRKGGEDIITVRRKNSAALPSSPPPLSPPRGLGLERRSTTDGTTATASDSANPTTTVISSGPGEDAQPKPSGLLARVKSLKGGRRPAPPPPPPMVNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIE3</accession>
    <name>A0ABR3YIE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein SEC24</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein transport protein sec24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">SEC24</name>
        <name evidence="22" type="ORF">Sste5346_010085</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000113">
        <property type="protein sequence ID" value="KAL1887637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01479">
        <property type="entry name" value="Sec24-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041742">
        <property type="entry name" value="Sec24-like_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="18">
        <location>
            <begin position="277"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="19">
        <location>
            <begin position="351"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="21">
        <location>
            <begin position="619"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="20">
        <location>
            <begin position="713"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="17">
        <location>
            <begin position="841"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1887637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="977" mass="106154" checksum="0BC6FF6C3A41F474" modified="2025-10-08" version="1">MSAPYGQQYGGQPSPYGDQQSFQDQQQQQPEGQAPPPASAHVPETGKKKKRAYAADAFNVGSAGAGGQVPAPGQYGVPTQPAGAPAYGGYGAQPAPDAQDVQYGHPQQPVVGAPGRVPAAGGYGYPDYGYPGANAGAPGAGGVDAVTAGVANMGFTGTGQPAAPHQQPHQQVPAQPGQPPRTGPLNQLYPTDLMSQPFNVSELDLSPPPIMLPPNSSVTPSPDANCPPKYVRSTINAVPTNHSLLKKSKLPFALIIQPYASLHDLDDNVPVVQDQVISRCRRCRSYINPFVTFVDHGHRWRCNMCNLTNDVPQAFDWDAASQKSVDRWQRHELNHAVVEFVAPQEYMVRPPQPLVYLFLFDVSYAAVSTGLLATSARTILDSLNRIPNADGRTRLGFIAVDSSLHYFAIPRDSKPAPKEEGQEDDGANEDDDENNGAGETSMLVVSDLDEPFMPVPQELLVPLTSSRQSIELFLTKLPGMFANNQNNGSCMGSALRAGHKLISPLGGKMVVLSSSLPNMGTGKLEMREDKKVLGTSKEGALLQTANSFYKSFAVECSKNQVSVDMFLFSSQYQDVASLSNLPRYTGGQTWFYPGWNAGRPEDAIKFATEFSDYLSSEIGLEAVLRVRATTGLRMSSFYGNFFNRSSDLCAFPAFPRDQCYVVEVAIDETLQKNVVCLQTAVLHTTCNGERRIRVLTLALPTTLSLADVYGSADQAAITAYFSHKAVERALDGGLDAARDSLQNKLTELLQTFRKELAGGSMGGGLQFPANLRGLPALFLGLIKNVGLRKSAQIPSDLRSAALCQLSTLPVPMLLQFIYPRLYSLHDMPDNAGVPDPETSQIVLPPPLNLSSERFVPYGLYLIDDGQTQFLWVGRDTVPQLLVDVFGVTDRTQLHVGKTTLPELDNDFNERVRAVVQKSRDFKSRGVGSITVPHLYVVREDGEPSLKLWAQTLLVEDRADHSMSFQQWMGNLREKVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIW8</accession>
    <name>A0ABR3YIW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_009655</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="12">
        <location>
            <begin position="16"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="477" mass="52528" checksum="2D0CBD3B00469946" modified="2025-10-08" version="1">MTTTPAYESVLKSQKYPAKAHAKRVADYIRSKFPDNGDGAAQNAVLYLESRATKLLEDNDEAEPFRQRRPFFYLTGCPLADSYFVYDVATEKSTLFIPPIDPESVIWSGLPVSAEEALAQWDVDEVKYVADVNPTLAAKANAVRANKAGAKSVVFAMEGQVSDQTTFLEFDGKDFSLLKEAIEECRVVKSAYELALMAKANDVSSAGHRKVLANVGKVSNEQELEGVFLGHCVAHGCRNQAYHSIVASGRAAATLHYVKNDQPMANKLNLLLDAGAEYQCYAADITRTFPIAGKFSTESSAIYDIVLRMQLECIDLLKAGVVWDDVHVHAHKVAIDGLLSLGIFKGDKDAILRDRTSVAFFPHGLGHYLGMDTHDTGGHANYADKDTMFRYLRVRGQLPAGSVITVEPGIYFCEFIIRPYLQDPAHAQYIDEKVLDKYWDVGGVRIEDNIVITETGSENLTSAPKDPDEMLAIINGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ55</accession>
    <name>A0ABR3YJ55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ChrR-like cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_010213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15183" checksum="C7AA433F965C2B83" modified="2025-10-08" version="1">MAFTQKEFCTRPVHPPVGATPVSLEEAVAASKTGDGKPDQWYTIGPGIWELLLNGDPTSDYKAVLQWYEPNTKSVDPVSIITHTYIEEVSFIQGGLSDVTLGEGWGPGSYAYRLPGMKHGPYQASPAGCLQFVKLAPVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJD0</accession>
    <name>A0ABR3YJD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="35800" checksum="1D5012FBA16ECEF9" modified="2025-10-08" version="1">MTTTYTAKTTGEAVARDSQTRIAGRTVLVTGTSPGGLGATFATTIAPFGPAHIILASRNTAKAEHVAKDIAAAAPAVKTSVVKLDLSSQVQVREAAAEILKISTHIDILVNNAAVMATSYSTTVDGIERQFGTNHIGHFLLTNLLLPKLLEVRAEGEVSTKEPLRVVNVASDGFRFGWVRYEDINFGDGATYEGWLAYGQSKSANMLFSRSLAKKLGSRGVVSVSLHPGVIITTNLSRGLAMEDISELGVLDRKLGNRSYWDNVVNLKSTAEGVATHVFAAFDASLDAPEVNGSYLEDSHVEDVGNVKSWARDSVDAEKLWNLSEGLVSQKFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJF1</accession>
    <name>A0ABR3YJF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF58">
        <property type="entry name" value="LOW AFFINITY HEME TRANSPORTER STR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="76"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="639" mass="69631" checksum="F051AEADBEC1FB1C" modified="2025-10-08" version="1">MSALPTNDQPIGVDPKGTVPTDPTKDHELFSSSEEKKEADESVTEGHHEVGVSRVEAFNKVLYQSGRKGKILLWMLGISIFLTMFVYALDQGITSSIFSTLAASTFGVHSQIGTVSTASQIIRAISKPFIGKLADITSRPTTYCIILVFYVLGFIVAASASTFASYTVGICFTSIGKSGLDLLSDIIVADLTPLEWRGFFSACLSLPFIVTVPINGFISTGFYGNWRWGLGMFAIMIPVLLMPAIITLYTMQRRGKRAGMVTMADSKDVRTGRAESSASNIQYWAGLLYRGLVDIDIIGLVILGFAFSLILLPITLAADAKNGWHNPSMIAMIVLGFVFLFAFAAFEYYLAPKPLMTRNILKNRAFIAGVIIHTFNQLASAVRNTYFSSYILIIKQWTTYQWTIFLGITTMGLCIVGPFVGLIHRKTHRYKTVMVAGAAAKVLGYGLLIQGNGNMTQDTARLVAAQLIFCLSSLNVVGARVGVQASVPHDDVASLISIITLWSTLGSSVGSAVASAIWTNQMLDQMRVELPGVPESTIKTVYGSIRSLRTYAFDDPIRQGSIRAYAIVNGHITTASICLSVVTLFASICMPNFYLGKQQNAVDNKGLDGTPVDVPDNYGHDTATGPRPWYKKLVNLYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJT8</accession>
    <name>A0ABR3YJT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045798639" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="2">
        <location>
            <begin position="40"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="437" mass="46883" checksum="F8C9C475D29D64E8" modified="2025-10-08" version="1">MMRLTLVAAALAGLVSADIPKLPLPASCSGVSAPHFPAMTLADGWKVTKILGGLKQVRVVIWDPLGHMLVSQATKGISVHTFGDDGCVNSTTMLVSNIALNQGLALTPDGKTLYASSERAAFSWTYDPVTMKVSNQKTAIGGIDQGIHSTRNLLVVQSQPNLLLLQAGSNANFDYAAQDKATGRAIVKIFDMSKAPAAGYNYKTDGEVLGYGLRNEIGFTADPNGHIWGVENSGDDFTRTVSGRRTDIHKDNPAEKLNYLGDPLKTRDVWYGYPQCFAVWDPSSFSDNKALKTGSHFVLAPNSSYSDDTCNGKAQAPRLTFQAHSAPIMNTFDADAKNMYVTFHGSWDRQPATGFKVVQIPFTKLADGRYDPVAPADSMKGYNDIWAASNPGSCTANGLTQSNCIRLSAASWDPAGRGLFIGSDNAAEGEVFILSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJW1</accession>
    <name>A0ABR3YJW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cholestenol delta-isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28448" checksum="A669BD0884229E3B" modified="2025-10-08" version="1">MVQTRSTSGVDVPATPSGRPRSSGNAAPSTRKATGSVRSRKSSAGPNGRSARRPSSSSSSVSSSFASASWVYIPDTLTLIWLAISLPLVIWDTGYVLGRPWTMPGGSLHWPIWSPYALYGEVDHMYGFKQWNAQNGFTAAQGTLNLIETALYFVYLYIWQTHGQALVSGGRKGLVGRAAAWAVILILSSSIMTLSKTVLYWLNEYYSGFDNIAQNDIYSLIFLWIIPNGAWLVLPTWMIYKIGGETIDALASTADHVKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKA2</accession>
    <name>A0ABR3YKA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009439</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="6">
        <location>
            <begin position="11"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="183" mass="20364" checksum="CFD7CA2A694DBEFF" modified="2025-10-08" version="1">MANPAPSDAIHVDLKVSGTNIDTAEDLRTDSEPIPSVTTKSHSRFPPLTPDWNNLKILHRNFHHESTSSNTQTRPMPSPMTSLNRECFQALYSAQFGLKLGLAGVDKVKWSGRGPGESYRDKKLSQRFGNWTLPVDDLFVDYEYPQDNGNRTGVQWVEFLGDSSTSSSEGANNRLLRAQVDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLR4</accession>
    <name>A0ABR3YLR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="93"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="593" mass="62685" checksum="70C3297E525CAEE3" modified="2025-10-08" version="1">MSSPSALAVPAKAHNANEIASSQASYTSADADKTDVEQGDITDLEKRPESAEKVDRDGDVDIEATAETKEAAVAGDAEDDDDEYPKGAKLGFIVLALALTIFLMSLDFTIVATAIPKITDQFHGLGDVAWYGSAFFLTVGGFQSTWGKAYKYFSLKYTYLASIIIFELGSLICGVAPNSKALIVGRAIAGIGAAGIGSGSYTVIAVTAKPKDRPMFTGLIGGAYGIASVIGPLIGGAFTDKVTWRWCFYINLPIGGISGLIILFLFQTPKRAQPAVATMREKLLQMDPVGTVLVMGGVISYILALQYGGQTDPWNSGKVIGLLVAFGVIAILFGCWEYYNGERAMIVPRIFASRNVWPNAIFAFFFASSYFTIIYYLPIYFQSIDNVSPTASGVRNLPLIIAVTIGTIVSGGIISKTGIATAFLPPMTALAVIGTGLLYTLDIGTGSGKWIGYQVLAGLGYGFTFQIPVIYGQATSKPEDLAPTTALIIFFQTIGGAFMLSAAQSAFVNHMVLELPKYAPSVNPLVVIATGATELWTTFPEDVLPGVLKAYMSGLKVAFAIAIAGVGSAFAVSLFSSWKRINPEALKNAGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMQ6</accession>
    <name>A0ABR3YMQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008908</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR VIB-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="126"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="126"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="40"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="511"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="636"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="751" mass="81294" checksum="5692B3F73889B423" modified="2025-10-08" version="1">MAELKEPAHGMWTGYGSPVQMANGRFGHPGALDPILANAAAAAPPAPSPHSARPRTDATGYPYAPRYPQDDTDVYGRHHSTSSASGVPHPSLTTHQSYPNLKRTYSQTEQHQQHQQPPQSQVPPYGDMVQDMRNEDGSKVNVNQGHKLLSFRRAADKHTIVDRHGRIQQLDLSAQLHGMFFLSEMPTSSSDGSVLQPELTCYRRNLFQISGTLITPRGQLSVVNEGGETVAVSSTELTISAIESVDNHPIRLIVIPWKTPPPNSPEVAQNPDQEPVPLPLIPFQDDGSEAEGEYAVYPIGWRRLQFRIATANNGRRKELQQHFVLHLKAIATLANGSKVVLAESTTAPIVVRGRSPRNFQARKEIPLLGSSAGSRGQALVETGMGIVAGPLTVKTQDKARAMALELPRSSFTFTAAPKMPPSPMSMRSNSYPAWNTQQMPLPPASGGAYPTTSMANEPYQKLPVSGSPHYTAEPQEMPMQQASSMPSVQLSLVANDHQQPNIRTQYAYVQGTSAPPPQMSLPTAGDAGGLSVPRYVDNNARPAKSPRHGNHDSVHSATSLSTSNDTPGEYRYGPASYMGVGGTSELSPHSQHQQHGAQHSPSQPPPPQQQGRPQHQHSHPQSQQQSPSQPLPLPHPQQQQHQGTPQQHQGQGAYGAASHDASGNSNASNPPSASHPPPRDYYPSSTSWAQPPADSNQAPYANGESRHYSFPDQYKAGHQVKNGEALPQPHNYAARGSFDATTMNHYSWSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMT3</accession>
    <name>A0ABR3YMT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metalloprotease m41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="466"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="749"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="781"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="804" mass="86163" checksum="BFE3711FBF3AF84A" modified="2025-10-08" version="1">MPPPTVQDLLRQLEEVQARAQRAEARAEQGETRVRVLETRQSPSSFLDYVRWTEKVLFQTFHIKPALMPQSERRSQAADTGASSPSPAHTATRVKGKFYPRRLRPWDFESAHASIFPALVAAFGEDKVFPALTDVIGIGRDLSPGPADEQDLRPFIRAAIEKPAARVVTQYIQQKQNDKASIDNGRGFLKITIQNNAYGVDLVQEAAEETPPPPPGQPGAMAPPPKRRRSPVKAIGVPDRWCVGFDDSGSATHILVGEYKAAHKLPAQKLSAVLSKPPGEDFFIQAVKSRDVDPNAADATTPTSAAAAAATQQRAAPVTGADVEHPRLTSEDVYIAATLCQAYHYMITAGLEFGYVASGDGLVFLRVLEDDPQTLLYFWSVFPVQAPAPGQGAPPGAALTSDDIENSTAGMREPIQTALAYLTSLCMLALKSTVRPMSWIDARERDLARWPLPYEQALPLMTTTALLPAHPGPRRDDTGGGAGGTGGSGGSGSEPSRTSTKRPHSALTASRTNTGSGSGTGNGNTARTHFVVEPPTLPYCTQACLRGLCTGAPLDDLCPNAALHRAARPPQAATAHGDGHPLTAGGVCERIVAQLAQNMDKDCQCLDRWGFFGRYGALFKLAVTGYGYTFVAKGVQAPHRHLLKDEAAVYTALAAHQGRLIPVFLGIADLARPLPLQSLARVPHLLLLSYAGPLLPDNTYAAAERGRTVAELQAAGLYNDDVHAGNIAWNAEAGRVMLFDFDQARVYQRPQQPEQSEPPAIPPPSTPLLACLPQTTKRSFTAYSGGATEGGTIPSPKRLQLQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN16</accession>
    <name>A0ABR3YN16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009323</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="150"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="486"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="575" mass="63764" checksum="F7ED67D9B855FCCB" modified="2025-10-08" version="1">MESEAEHVPKRRTLQACRTCPSPRLERHAIATPTITRRALQRCTAIFCERHLTCTFCSFIHRPDLDALSASPSSFLALVIVCLCSRYLSTKEAEELFGPSLSSGWQVCRRFTPAAKALARSTMDDPSVLHIQANLVLAVSELLNNEGSSHWMYAGTAIRMAQVMRLNQDYHQQHSLPEQEIRRRTFWACFSVDKLLAFLLTKPGTLALGNVAVALPSTDAALAYGEATRGLTLGSSFEGAMPSQIGLLPYFLKTLTLWSNIVDRRVCHSRFVTKTLPTDPAGRFYQSHQALHDWDSQLPAGLQWTPENRANHHTALNQGRTFVAMHFLIRSAFCVAHEAYLPQLDGSSVLVNAVDAAGWSLLHREPSLLAQCVTSALAVGVMLAEVEAEKGGDGDDDGDTDMLQSVWVASALLSVSNTLLWLQYAHDPDYADDQTVDKARHYWSMVTRRMQSWAKSWKAARQWLKGLHGMQALYRAAYLGEVEDEEAATGDVSSGDEIDGDSETPSFRPRAGDGYPPLTAIPNLYASLRFLASDTSAEPKRLQSVWMSFVSGWSFVNLTNPDMNDNPFAQLAQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNN5</accession>
    <name>A0ABR3YNN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="126" mass="14477" checksum="5A9035E8BFCD2F30" modified="2025-10-08" version="1">MVVDTILEAYGLMDAMYAKEEEVEAAYGDESEESEDYKVLLHQCYGRLFEKVRTKGQDDDASDDERQQFSAQVDILAKSNMRDSIFAAIDALTGPTSTFYWMPMLNKRTEQFKSCFRGMSRLARKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNS6</accession>
    <name>A0ABR3YNS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial 2-oxoglutarate/malate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_008602</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="117"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="218"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32119" checksum="3F1CE994E458DD61" modified="2025-10-08" version="1">MAVDLSQPASSRANSLLRASIPFTVACGSSMVATVCIQPIDTVKVRMQLMDSGSGIRISPVMVVRDIVAGRGGIFNLYQGLSAGLLRQLVYGTARLGLFSTFERKLIQRAHDRGTTLTFGGRALAGLGAGAMAAFIGNPTEVALVRMQADTMKPPSLRRNYTSAFNALARITREEGVLGLWKGASPTIIRAMSTNFGQLAFFSESKHQIQKHFGDNVSAPLRTVCAAFIAGLAGAVVSLPFDFVKTRLQNQSMAAATQGGLPLYKGTFDCFSKVLRSEGPMQFYRGFWPYLMRIAPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPL4</accession>
    <name>A0ABR3YPL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Polyprenal reductase</fullName>
            <ecNumber evidence="5">1.3.1.94</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008673</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a di-trans,poly-cis-dolichal + NADP(+) = a di-trans,poly-cis-polyprenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:80727"/>
            <dbReference type="Rhea" id="RHEA-COMP:19536"/>
            <dbReference type="Rhea" id="RHEA-COMP:19537"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:231623"/>
            <dbReference type="ChEBI" id="CHEBI:231637"/>
            <dbReference type="EC" id="1.3.1.94"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:80729"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the steroid 5-alpha reductase family. Polyprenal reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.94" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="233"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="346" mass="38260" checksum="6C01BB121EE94851" modified="2025-10-08" version="1">MSSVSPANLCQASFAGLAAAIVALTLLPAATQKLLLDYGARDSKSTVAAEPKGKGTAKEDDKQAPESEPDLLTRIVAVVVSRLQVPHSWFISFYAFYLICTAYWAAQWWLWRQADVSGQKTTMPNNLFGRILESQQLSDLVGTPTPATSMALAQVAIAFVLEALQTGRRLYEYLYVFKPSKAMMNVAHFLLGFAYYAIMSVAVWVEGSQAILATRHLVATSPATALANSNEALMKIAIGTPLFLLAWVGQYRCHVHLASLKKYTLPEEGLFRYFVSPHYTCEFFLYVALSVVTAPEGKLFNRTVLSSLLFVLAGLGVTADRTKKWYAEKFGAERVAKKWRMVPFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ4</accession>
    <name>A0ABR3YPQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616:SF1">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047090363" evidence="1">
        <location>
            <begin position="24"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="558" mass="61787" checksum="97E5A6325E4870F0" modified="2025-10-08" version="1">MRPNTIFASLAGLAMGLVSTVEATKMTSHAHSMFHKEMKFLDNLYDPVAGYLYYFYYPLAAGPHETRSTVWYATGLLQRNEGNDTVNAVRIIKDVIANQEKNVSAQWYGDYTVYPEQPTVGSPSYAPVIYNSWDPNWRGFIGTTLIIIYEEFGSLIGQDVKSLILESLYNNTIGDSYRVGGVDGDNLYPSYSNPSLMRAVVTGWTGNHCNDSNMTAAGEMYAQEIIDLFNMNDTLAEFNVPTYYGVSLNALTLWSKYMPASSVMRQNGPRMVGDIWTAFGDFYNAKLRNLAGPWDRSYGYDMNRYVAIMSLYVWSLVGREHVFSGTGTESPWLLTHADDGEFIPVVATLSEYHRTLVPHAVLSQLTTFEGNASRTVHRQAYTPPFDLEVRNITTWLTPDLQIGGDSYNQTVVGGASQDSTSFSPAVVHWHRNATTFERESVGYLSLHPSEKSMQASVEANRLSLTYPAGNASSIFTFVVSSNPLGSSRRDVYGLADIDGINITVGEGSTVNPEPVVAFCGLVGGTCSLIHNFEFWNLTFTMPANSTALPQLNLNIELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQE1</accession>
    <name>A0ABR3YQE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-induced protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF4">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27213" checksum="63ACB4877EA2469E" modified="2025-10-08" version="1">MASSPKPEDLPYWQVNIPADQCTAACPDFLLNINDKDRGIISTREEDYQLMSWPEVRALIAANQLQLFQRTPLALRRYLDYGWGLKEKYGSAVNFVLQERLHWNPEELAARAEKDAGKVPDFSDPSDVKILCNDWPYGLDERIVHLVVWTKFPLPDDPTTGDLTDDARAAIEAYVQKTFRAPLPKDSVIWFKNWRSLKSVLLVEHFHIMLFDPLEEFIAKITNGDVPLSKRLAEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQE6</accession>
    <name>A0ABR3YQE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Slx4p interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SLX1</name>
        <name evidence="12" type="ORF">Sste5346_008506</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a heterodimer with SLX4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SLX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10455">
        <property type="entry name" value="GIY-YIG_SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03100">
        <property type="entry name" value="Endonuc_su_Slx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027520">
        <property type="entry name" value="Slx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048749">
        <property type="entry name" value="SLX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050381">
        <property type="entry name" value="SLX1_endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208:SF10">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21202">
        <property type="entry name" value="SLX1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="11">
        <location>
            <begin position="12"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="475" mass="50943" checksum="1AA5B8D3E9DE9C3E" modified="2025-10-08" version="1">MASTVSSRPIPALYAVYILRSTMRHASLYIGSTTDPPRRLKQHNGAIKGGAARTSRTSLRPWEMVGLVSGFPGAVAALKFEWALTNPHLSLHIPAESRLSVASQKKRNGHPKRPPASIHSILANLHLLLRVPSFARWPLRFHIFVPEVHAAYKKWSQTSASQQLGDDVREVEVLTDFPPAPESIYGGMTATTGDHDDDIEMSGPLWGIHALPLDYTPMRDYVDKARDIFAFEREGDCTVCHTELPAGKGLYAVCPNTECEAVGHLRCWSSHLLTGEKKTGTLGVGGSDDALVPVRGHCPDCGGPVVWGDMIKELTLRMRGPKEVEKLVKAKRRQEKAADKAAAEADKAAEKASKAAAATAAALAKLDDLSDSAEMTLSPRKKTTKKETTTKAKGKAKAVDKTAAAAATTMTKATKITKTTRVTKATASASTSKATKATTTKKGKTTAAAEAATAAISRASEDLLNRSESPEVIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQH2</accession>
    <name>A0ABR3YQH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="530"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="757" mass="84493" checksum="4BD22C0E9AE79940" modified="2025-10-08" version="1">MAPALTQDEEPVAVVAKTANGVESVDKAEKVEDKAEGKAEDTTTSEAKTDSETTTPDEKKTVVGMECAQKDLYQKWDKQNRFTWTDTYPKDLEEAAENEATEKFAILVRNKKSYDSRKSLEIDSIVIQSPLLKNVLRNVLDDYPGVAPGLQRLVFSAPFQPFVHRWDRLKAALTNTSEYDEATRDHVRLLYDLLHTELKDTIRAVDDYMAQGVVSYEHAWTVFHPGCTIVTSRYGHPVANRLKQGQYIKHARLGPCFELVAERLEYDGHRFGYDTAHVYVLPFVGTVPIATLDAFPLDYHPDPASVRASLLERGQRFAALAGWHYMAYKGTAIEQKENGPARIAIDSRIVVDAQTHARFNADYATSLAHLTKTNNAVRKAQVETADDEFNDPGTDNGMDDGQNLRMRIINGRVIYDFGDGSDGEAMLKFKKEGAEGEDEDESEAASAHRQAAALTEDQLLLASPMVKGYCLRTKKWLEFYVDSVRPIQFNEQAFDRLVLPAGHKQLVLAFTQSQIKNKHKFDDVIAGKGKGIIMLLSGGPGIGKTLTAESVAESMRVPLFVMSGGDLGMTSNEVEFNLGRVLDMVAKWNAVLLIDECDVFLEARTAADLDRNRIVSIFLRTLEYYEGILFLTTNRVNQIDEAFHSRIHISLAYPRLDAAARRQVWEGFLGENGKMGHGAEAAPTEGTAKPAEEEKVKPKPKVHMVTADDITRLSELDLNGRQIKNFVKTSHLLAFQLGQTLSFEHLQTVLQIEGHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR03</accession>
    <name>A0ABR3YR03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleolar complex protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NOP14</name>
        <name evidence="8" type="ORF">Sste5346_008247</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007276">
        <property type="entry name" value="Nop14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183">
        <property type="entry name" value="NOP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04147">
        <property type="entry name" value="Nop14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="353"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="476"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="353"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="988" mass="110435" checksum="BB8A48A48BA12D15" modified="2025-10-08" version="1">MAGSQLKRLKASLLDQGIIGPQKSKKQKKQAAEEARANQAAGRGGDKRLKKSAALETIREQFNPFQFKMNARGPKFPVTSLKASQVPESLRGIKGRPTVSLSKGEEKRRATLLLDMQRRNKVGGILDRRLGEGDPNMTPEERALERFTFEKQRMHNKKGAIFDLEEGDSNFLGDADDGGLTHMGKSLSFGDLRGRRKFDDDDEDGDVGEIKDDFDEEDLAGSDEDEDEDPERAYKKKQLKRMHDELFGDKEEGTGAATNGEDGAPERKKSKKEVMEEVIAKSKYYKYERQLAKETDDDVRAELDKMLPELQTLLSTKPVKPTPQGQDVAPIIGAPFDKDAFDKTYDVRLRQLIQDKKAEPSTRTKTEEEIANEQSEHLKKLEESRLRRMNGEIGYNEGGNGSDDESDEGGKGNKKSKDKKDKKDKEDGPALQILREDDEEDEFNLGQGIKVKHTAAELGFDDEDDFLIDDDLVFSGSEVDVDESDEDDSGDEGGEEGEDNEEEEDEFIRGLLTEDEKKNAVFANAGKLPSTAPKGLDDDGVPYTFPCPQTHAELLVVLEDVPVAKLPTVVQRIRALYHPKLDHGNKDRLGHFAAALVEHIAYLANGDEPPYATIESLVRHIHSLAKTVPIEVAVAFRTHLAAMEGIAIGDDSNKSKTKADSRAVALNSGDLAILTAAGSVFPTSDHFHQVITPAMLAMARYLEQAPPRSLAEYATGLYVCTLLCQYQRLSKRYVPEMVNYVLNTLLALAPVGSDALANPATGHFPVHTPVRGVRIEKAQSVKSVRKLRISDAKSSSETNELKAALFSTALALLNDAATNLWTGKASLYETLEPCRAVLHHLRNTKTCRSQLPPPLNKEVDRLAAQIDAAQRLAHLARRPLELHHHRPLAIRTFVPRFEDEFDPDKHYDPNRERAEAAKLQAEFKRERKGALRELRKDAHFMQREKLKIKKAKDAAYEKKYKRLVAEIQGSEGREANAYERERQARKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRG5</accession>
    <name>A0ABR3YRG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008273</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="671" mass="72619" checksum="EA4BFC30E171C0B5" modified="2025-10-08" version="1">MTAPQVCTRCRKRRIRCDLQLPACKNCRLADVECFFWDNALGQEMPCSYLYSLRQRVAGLKRDMEAIQARQKSSTATVPASVSTISLSTLDLEGAALSALADLSQGLQCGGAWSRPAREEKAGKRGDYHLLRSTPLVTDEGDSVGGDGLTATVPSQTAYLGPGSTARLAEATLNAAVDWHAAKGVQLPTSLQGTEEAEDPLQNVPLSLSSQTRKGILGMITSSEDSPPPLTILHDPRKEAELHTLVPLATQRVLLEHYSAVCGASSPCYDSLLPAEQEAALLQRAGSGSENPLKWASANRGTAGAYATTVVFAVATALAARDLKVGSDGGRMAALASRFRDDVQALVGVEVMKGSQDNAESTLSSLERTRWTATALATMVLCEMIQPTTSQMWDLLGAATSVLNDLREGYCLRHRTPESDADFVRLERTMLRMEARTSLHFRRPSPFCDRYLLGPGSFSGGSSELEWQQLLASSFTPASSVVIDDLVVLRSTLLIRQQLELQPTPPEHFLESLIPAPLQVLGVPPLTRASLADATAPLMSVQSASLYITLYPVAMSPDMIVKGDAAQPPSRLFQLSAAAACVLLNEFTRQNPRHRIVSLWMSAERIIEAGIIWVLYVLAQQNHQQLDIGTAMRPVLQASGLLASFASRWKMGKAHVEAWDTLVELMWGILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRW5</accession>
    <name>A0ABR3YRW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T1</fullName>
            <ecNumber evidence="2">4.6.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007856</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[RNA] containing guanosine + H2O = an [RNA fragment]-3'-guanosine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment].</text>
            <dbReference type="EC" id="4.6.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.24" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104:SF1">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="191" mass="20098" checksum="F9DFCA7FCF359A80" modified="2025-10-08" version="1">MAEHTIYYSPSFSEATHKATFTRDQINAAIGQALLLLKEGKQIGESKFPHAYKTYPLPASAGKHAQPPIFEFPILLDGSLYKGHHSPGPDRVVFGSVATDYASADYVGIAGVGPDGAGATAPSTPGGTGSGSYTPHIFRDTSVNRGSGDGSGHSHTGHHHDHEGKTATPPLTPPDERELISAEDVTIHFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSH7</accession>
    <name>A0ABR3YSH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019431">
        <property type="entry name" value="DUF2417"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10329">
        <property type="entry name" value="DUF2417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="62279" checksum="9C8C76E1B38BAA96" modified="2025-10-08" version="1">MKKFFTTADNSSARSQGRPELDESASRDSLDQPSSAGPPPDETTRLLPNRIDSNYNGYLSPDDPAVSPYNLFSVRAAHYFTGFLLILTSIWWILLLVSLFVTPPGFETRGSPFTAFSYATVAVTSLAVCLLFFAAPSKSVRIITGIVALFLFINTIITAAVERTRHEEGWVGITSVTWALAMAVWTIIADRTVQWGKREEEERLTGRPESRRTLLEWIEVSVSSIILIILCVVTALLTCTLILRSLDAGLAPLGKRYWVDGNKYEIHVYCHGSKSKEPLPTVLFEGGDDPVENGLWQFAQSAVQNGSINRYCFADRPGLGWSDTAPSPFSAGQATEALSEALAHAGETGPWVLVGAGVGSIYSRVFSSRHGTEIEGLLLLDPLHEDLLDRVGASGRGFWLWLRGVLSPLGVDRVPGALFKGRTREDRVWGRAAYQNSKTIFAKLQESLVANSLTKRDAITSRAIQYQDTPLALISSGNQIKKDKVWEDKQKDLSKLTHTLLSWDIVADAPHEIWRTLEGRELIEKRLKKLVRRPAKHPGTKEASEAVEAKEEVATDEENVGEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSK6</accession>
    <name>A0ABR3YSK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dipeptidyl peptidase 3</fullName>
            <ecNumber evidence="11">3.4.14.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl aminopeptidase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl peptidase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_007717</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.</text>
            <dbReference type="EC" id="3.4.14.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.4" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005317">
        <property type="entry name" value="Dipeptidyl-peptase3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007828">
        <property type="entry name" value="Dipeptidyl-peptidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR007828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="714" mass="78387" checksum="DB7F05C85D35EB47" modified="2025-10-08" version="1">MALTAQELSQYLADAPPSVVRLEIAKHFDALSDSQKRYAHYISRASFAGNRIVLRQVSPEAESIFDFILALNTAAAGDWKGLAAKAGVEEAHLTAFLQYAAQFLGNSGNYKSFGDSKFIPRAPESAFAALASTSPDAEKHYKATKGAIFSSDNVGLLHLGYTDDGHLTTYYPDSPDITKDEIAGVAKWMEKKGLLPENTRLRKQKGSNVFELLIASGQTSPPVDGRDIGSIETEFSLDESDSAGLKGATIRLVYGDYATEMAEIAKNIAQAAVNADNETETKMHEAYAKSFSEGSLLAFKDSQRYWIRDKGPMVETNIGFIETYRDPAGTRGEWEGFVAMVNLERTRAFGALVDAAPTLIPLLPWSADFEKDKFLSPDFTSLEVLTFAGSGIPAGINIPNYDDIRQTEGFKNVSLGNVLSAKAPNEKIPFIREEDLALYQKYRDGAFEVQVGLHELTGHGCGKLLQETSAGVYNFDHNNPPVSPLTGKPVTTWYKPGQTWGSVFGGLAGAYEECRAELVAMYLSCEFPVLKIFGFGDGSNDIDGEAGDVLYASYLSMARAGLTSVEFWDPKGQKWGQAHCQARFSILKCFLEAGDDFCRLEYKNDDLSDLTIKLDRSKILTTGRKAVGDYLQKLHIYKSTADKTNGVAFFADKMSAVGLEYWGTKVRDVVLKNKQPRKVFVQANTYLDEATGKVTLKEYDATPEGLIQSFADRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSQ7</accession>
    <name>A0ABR3YSQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057088">
        <property type="entry name" value="GLRG_09195_Thiored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF5">
        <property type="entry name" value="ISOCHORISMATASE FAMILY PROTEIN FAMILY (AFU_ORTHOLOGUE AFUA_3G14500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24470">
        <property type="entry name" value="Thiored_Isochorism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="742"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="789"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="516"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="538"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="580"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="790"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="809"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1192" mass="128003" checksum="66C6C447D3431266" modified="2025-10-08" version="1">MPPTLPIDLANFPALQTRKALLILDLQNEFLSPSGTLPVTTPNGYVERTLKIAKAFRESGSGDVFWIRSQFDSHRPTENAQIITSASSSIASPRQSTTCGRRRESEPTAEDPDADPEAFLSIGGATPQDKQKQQQQRSQCLLPGSHGSELAQQVASVVNARQDLVIAKSHYSAFESTQLLMRLRTRFVTELYICGALTNISIHATALDAARHGLTLTIIEDCCGYRDVARHSDAISSLVQLTGCDTLSADHVLEGLTSQSSDAKPAGNDFAAAIAAITAASNGPPRVRRPTKQASSGPVAVGAGGGTSGGIPVRTKTQTPEPRKDDKQSDVRTRSAPSSHENSGLSRLSPTATENVPKPEPETTRPLQPVVANDAATPTTTAASETTTKITATKSVATTITDIAATTTAPPVVTGSKSVVGAGAATVSTASSAPASIAAAKPTSTRQTTPAPIEPLTIDAGEISADEDAGNNDDSDDSFKLVIPSRHEKLLEYSRLRSTRNANALKKRLEEGTKESASAASGASAVPSRVEQTRVRRSPATSSSRATETRSSNSAPIASKTMSTSTSPKPAKEASPVSEADTSAKVSSSPVEETVKPKKDASAKTPAKPTEKDDKDVSKPDEQPETESDSEDADAKLVPVDVTKKPSATEPICAGDTIIYHDVLPQSLEKGIYERLKDEVQWLRMSHQGGEVPRLVCVQGQVDEDGSIPIYRHPADESPPLEAFTPTVVQIKSEVEKIVGHPLNHVLIQLYRTGNDYISEHSDKTLDIVPGSYVCNMSLGAERTMIFRTKRVDKDPSRKEESSSTTDPTDSKATDSKAADRKPAATPDSTKRQSCRVQLPHNSLCRMGLQTNMQWLHAIRQDKRIKREKTPAELAYGGGRISLTFRQIGTFLNRDQTLIWGQGAVGKTRKEARSVVNGQSDEAIRMLQAFGTENHSSVFDWNKHYGKGFDVLHMSSSPRFFASVDPVVNMTVQLLLAELGINYARGSMAAAVEKKDATATTSSDVAEMVTPVSSLDVPVRLVDNDRDRSTVHGVLAILLYLDSMYAPPPKGRSAHRHLEAARKFTRLQQALLLQDKWRSTPKTVQTDEASTSGATSAFSLRPLKCELAVWDGYVSVKTGPTDVSDEFIAGGTTPSVADFALWPVLHSMELAAGSQDALEAELKRLGVPGLAKYYTLFKARECVEKVLKAGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT70</accession>
    <name>A0ABR3YT70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secretory lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045017775" description="Secretory lipase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="47623" checksum="CDEFE111F84ACEF0" modified="2025-10-08" version="1">MRPGILVTVAFAALSWAAPVTEEKRATPPLPSTDSFYSVPDNIASYAPGAIINHRAPPSPISAFGIDPVNIAASWQILYRTTDNLGNATATILTVLVPVNADFDKLLSYQVAEDAPNINCAPSYALQLESATGGTLGTALTQAELLLAEAALYQGWVVVLPDHEGPNGAYLANRLAGYATLDGIRAALQSTSLTGISIDAKVGLWGYSGGALASAWATVLQPEYAPELTGTLVGAAFGGTVPNIYNVITTINKTPSAGIIAAGMVGLAKQYPVMATGLEDHVLPEYQADFEAVLNQCFVPDLSLFNNADVINMIDNPNLWNDPVVLEIFANNSLEYAPAPPAGLPLFVYKAVKDEVSPIADTDDLITAYCAAGTTVEYIRDQSSTHGGLSLIGAPMALAWLIDRMNGKAASTVCSTATKYSMLLDIATLEVLPTFLLDALKALLGGEVGPTFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTF4</accession>
    <name>A0ABR3YTF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin-repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NAS6</name>
        <name evidence="4" type="ORF">Sste5346_007552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="159" mass="16973" checksum="BE9502241E4D06BF" modified="2025-10-08" version="1">MIAASVKDSEPLVDLLLNRGASVDEKNNNGQTVLHFVASKSNLDLAKKLLEVSPPASARVRDKRGQYAIHRAAAVGSSPIVTLLLKHRSPLNATDNEGQTALHHAVAEGHGDTAIVLLKAGAETDKKDQSGFLALDLAPDREVHKYITQTAEKEGIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVU5</accession>
    <name>A0ABR3YVU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF414">
        <property type="entry name" value="CONTAINING AMINE OXIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="61"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="598" mass="65186" checksum="41EEF6F547E5D498" modified="2025-10-08" version="1">MKMDVYSVFSSSATRRDCSRLDLDLKSIRRSSSSAADRPPAERTPSPSQRSPHIGIVGAGIAGLRCADILLQHGFRVTILEGRQRLGGRLHQVRLQPTLAASSNGGNDDGPLVDMGPNWIHGTTDNPILDLVRATETVTSSHDVDEDGNDLGGAVFNVEGAILPLEEGEALSTIMWTIVEEAFVHSNANCSIIDPKESLYDFFVQRLDFHIPPAAEGATEAEKEAVSQKQKLVLQMADFWGAFVGSPVGRQSLKYYWLEECIEGENLFCAGTYKRVFDRLIEPVVEGATIHYSKTVSRIVSTLDDNKREVGKFPGSSVSVSTSSGETFSFDDVVCTMPLGWLKKNAATAFKPAIPSRVSEAISSIGYGSLEKVYVSFSEAFWQRPDPETGRSVRGFCQWLAPGVYAQQSNQEHWSLEAFDMAALPASVAHPTLLFYTYGEQSAHIMGTLASLRDKSDGQTSSTNEPSEMRCPNAKQTAFLLDYFRPYFATMPHYDPASPACQTTGIITTNWLHDDLAGNGSYSNFQVGLARGDEDIRVMREGLPGRGVWLAGEHTSPFVALGTATGAYWSGESVGRRIAEAYGLENEDDKGSAGNSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVY9</accession>
    <name>A0ABR3YVY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Urease accessory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="41342" checksum="F374A8F33A272D10" modified="2025-10-08" version="1">MVLSPFPPSTATPGDGRIVASLMPNGEPGLGVVSYQYPLKLIAPTTGAGLGTLGPTGAEVVSDDKNEANPARRTSALVFLLSYGGGLVAGDQVNLKIEVEAGARLSLVTQGTTKVFKATGDGRAAPVATPTRQNLTMDVAPGGGLCLLPDPVQPFAESVYEQVQIVRLDERGAKTSGTDTKVPSLCLLDWVTQGRAARGENWSFTSWKGRNEVWIETGDAGNGSGSVDKTTTDTASIPHRNRLLVRDSVMLAPGYLDTGVASLPPSSDTALRDSLQGLAVFGTLILRGPLVDAAGTFFLEEFAALPRLGGRDFRDTDTPSPSKDTESLDAWRAERLKLEAAQGVLWSAAAVRGCVVVKFGARSVEGGRLWIGSMLQREGSVAAAFGDEALMCVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW04</accession>
    <name>A0ABR3YW04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Karyogamy protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013889">
        <property type="entry name" value="Karyogamy_KAR9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37271">
        <property type="entry name" value="KARYOGAMY PROTEIN KAR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37271:SF1">
        <property type="entry name" value="KARYOGAMY PROTEIN KAR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08580">
        <property type="entry name" value="KAR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="942"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="783"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="942"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="999"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1194"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1257" mass="135296" checksum="2381207A9BB01D23" modified="2025-10-08" version="1">MTTTFLTSAPGVTVVAAASESSPLSPFVVADAYEYGPSCSTVPFQQPVSIPAAAATSAASATAVLPSPHSTPAALGGGGHLHLQTDIPGQSQPPRLSSAFPALAQSPSPSDRHNSTSNTSDGDATSSVLTFAEIPSDLARLNFNHQRMPDTDAHVVAPVDSSAPTSTTPLKPPTHSHIQPPYTQSQSPQLLTPSSSPLRPVRRVGFAATTPDDNRAGDFPDTGRPRVSSTASSTSSNTPVQHPQPRKPSPGLAARLKALGFGTTTRKESPPPPPASANQPERIGRLPEDQLRQIDQNHQAGSSQLVVERRGRPWKGAGAAVARFPASVANLATGRGKQTTDADDADPYTDSSTNATATTAIVVVTEPEENNIDTASISPASSFLPEIAPTQPLDMDTNKYRLPDHTNGNGTKVQLDTRQQHIERDSTATNQSSNSSLRIASPDIPPPPPAKDTPPLPQQQQAAAAPETPSQSDFNPDAASYFNPLGLQRPGSIYTLSRVSFANQLAQLTSLQLPDAESLSSRVSAIPTAQAASRALIGAAEQIRNWISKASEVIEGLDSDDDVEWAAAGGREGLEEVENAIIRFEELINIYVGAIESLQCRPDIASVTRDELQRAVYQMESIMEEWGRMRNALQAVKAQVEIAMEWEELWGMVLGDIQNEMDELSRLVFEMEERRHQSLADGPGVDIGDLETIVEENQHKQQLSPNAALSRTTSANNRNSIPIFPLTPVSPEARSATPTISQDDSSLLALFARMQPLRASLDFLPMRLSVFETRASNCFPTACEELEMRRSGLDGTYKKLEKDAESLRKELGEDRWVTVFRGAARQAQKMYESVERSVVKLKEGLDMGMHLTNQPVMVKKIESYETKKMHYGPAIERVLAIIDKGVKDRLTLNGEILRLHVELQTQWDELRDRMHDIDLAIEELHSDDQRNQQLRDSISSMLSNDRSTIGSGRDTPQSSPPSSVIMSTLGLDNSSSKRLAAKHADVNGTPTNNRRRSQLGGNSHLPQPATRRSVSSSVTLGAAQARKSLSRFSSSFGPGGSSLSSPGREGSVTPVSKRLSTQPARPPSTLDHRPRWNTSTTGIDTGHNFKPLSLTTPSPYAKTPPSATRRSTAGTPRSTSSLGTRLPMRSPLGRGVSSSPVPHADGSPSRDPPGFRDAPPYRPPRLAAHSSAPPAAANRRASMQPPQAHAPSSPYVTPQRPASSMATGRRSSLLPAPRTQEGSVSGRESPQAIAGARFAMRRKPVETKPNDKPKWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW65</accession>
    <name>A0ABR3YW65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1892003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018744">
        <property type="entry name" value="DUF2293"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113:SF2">
        <property type="entry name" value="DUF2293 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10056">
        <property type="entry name" value="DUF2293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2293" evidence="2">
        <location>
            <begin position="96"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="360" mass="40199" checksum="37D7565483E2ACBE" modified="2025-10-08" version="1">MLDGKEVAVHPRTPMPPFYTFVPKGNVYVTTNCRRKTHQAGQTVYVVTLHKKDLGLRCPTTIVQAVRAAEKATRAARHDATAKRDAALAATFKKALLARYPKVPADTVPEIVQHALKKRQRRVARTSTLDEDQRVQLAVRAHIRHRWTDYDKILREGDKIKGRKSEKKGKRGHDRTQRQRREARAAIMGRVDAIEREWAGGKAPQQSGRPSGNGPIEISDSEESMDESEESEEDEEEEGDDDEDDESEDEFTEHSASERRDRRIGKGASIASQSNEQLPGRKAGSGSGNKITGSRIQKTTTTPPAASRHPRSSKSRATVRIARCQQKIDRLQAAAAQSDRKDGDKKETAIVIDSDSEWEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA0</accession>
    <name>A0ABR3YWA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box protein: endocytic membrane traffic, recycling ReCYcling 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RCY1</name>
        <name evidence="3" type="ORF">Sste5346_007265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF1">
        <property type="entry name" value="RECYCLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="916"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1103" mass="121184" checksum="B0B58950170D0B1F" modified="2025-10-08" version="1">MSRAYNNGRPGAGPGTPNNKSILGVLKAAEIIESKTTLSAEILATILDYLPIPDQISFARTCRRMREMVYDDTRWVSRLQSMGAWNETEARRRFDEAMQKRRRDTAAAAAAANAATGVGGNGLVGGGSGVAHGASATPGSRQASGSTTLFDASLEEERRRQLRLQQQQQEQQQLVRARDGFETLTIGGDEAQSQPPGASAAEKSPLQDSEALLDVFKNVQSVRGHARQEFGRIYGALGPFYWDLQRSRTHADPAIFKVFRDPERQARMLANLRTFSQSDWAQGWRQREEKLTSMTSIFESAVLREFEQGYEFWDVDGRMRKYAHVLDVLGGSTAGVDLFIQKHPLFDDHELTSMNAMDCINLAPRATSSPDNLITLDPSRAFFELLTRKVNEQSSVIGRIFPRPGRVFWALVDKVREDMIMEYITPLLDETHERNLPAYLTAVSGLFEQALQFLKALEPPKSPDADKPKTGSATTPKKHTKNTPSTASDEFERPGKLKRRSTKTLPPGASVPGTIEEEEDEDDEDAWRPKARLRKVRELAFRTFEPHLDLYLQEELDYFTKHIEAEVREWDKKLSEQDADAESFYMANFNRQEVKKDFLSSFKKVVMMPVTVLPSLPGQLNPFAASSSTKTPGASDTNLSLPQQPQTTTASGRATPNPLSQLPEKAPDDELAAKAALMTSRLEGIKSLFSLEMALNLVHAAKTSLGRAAVFVQLGGQAAGEAREQCETIFVVLLRILGNGHVKQGFDKAVEHLSQYNPRTVVVRPTSTISTTGEGSNGGFGASEKDAAANSGGGHDGGVAPLMTFIELVNVGDLISQMIDVFYEQQLAGPKIADRNDFLDPAGLAKKRFEQMIDESVAAGLNKGIDVLMDEVEYICATTQKPTDYYPEAVEAVAESGLSFLNGTLSSVTGGGSSSGDGLSTPKSGGSAASPGAPGAPAASAFDPFAAADIGPTQTAMRVVDLVRGHTNMLKGSTEKTMLDVFNGEVGLRLFTAVCKHLKRQRISMAGAVHVIADMTLYFDYVRTLRNPDLLAYFRALRELSQLYLIDARHHAKEMAVIIADGDRFGGVFRAEEVYEFAERRADWYQVKRNVERAMYGLECSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWJ3</accession>
    <name>A0ABR3YWJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Histone deacetylase</fullName>
            <ecNumber evidence="2 8">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HOS2</name>
        <name evidence="11" type="ORF">Sste5346_006831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 8"/>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF36">
        <property type="entry name" value="HISTONE DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="10">
        <location>
            <begin position="83"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="497" mass="55731" checksum="E650E71B0C0860EF" modified="2025-10-08" version="1">MTDISSYRYRVPRPNYLPHNVDADPAVVEDYVPLGSASELENAAYLAKAKKAAQQYGLVRPKGYNVTFHTNPEMEKHHFGQTHPMKPWRLTLSKSLIMSYGMPFAMDNYIARAATFEELNSFHADDYLDYLGTVLPEPVPRDLDSTNPPDLKFNLGGSDCPLFEGLYDYCSMSAGGSLDAARKVCNREADIAISWGGGLHHAKKAEASGFCYINDIVLAILQLLRCYPRVLYIDIDVHHGDGVEEAFFSTDRVMTCSFHKYDPINFFPGTGALDDNGPKNEFNAGAHHAINVPLNDGITDEQYAWLFDSVISKIVETFRPSAIALQCGADSLAGDRLGRFNLQVQGHGQCVAFCKKLGLPMILFGGGGYTPRNVARAWSWETAIALQCEDKIDPMIPAHTPWRDHFRQEELLPTLEQIVGEPRQNKNPQKRMQEIVQHVHEQLRFVQHAPSVQMRDIPPDLGGIRQEVDEMLREEAETKDDALRKTKEEGLGVAMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWJ4</accession>
    <name>A0ABR3YWJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF2">
        <property type="entry name" value="WW DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06520)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="621"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1345" mass="143785" checksum="E776E959C05E71CF" modified="2025-10-08" version="1">MAERSRGVPDAELFLSRPSDDCDSPTVEPLRIFKPQSPNPYSATSAGSGDYSGSERFRYPPPPGATTSTGANNAAGAPAASRPSFPLPPGASSSANPLPYPVDDDQIIPPAASTVNKPRPPYPDERPQINTNITGSSYNDTSPRLGMSPVSGKKPGLAERRGNIPTSLSPSSPTDNDDFFAKPITQPAQQRPAQQQQKPAVASYPPKSYYHPPPVGSTASSTTSSSSGGAGVSASTAPPTHVNPYRPARADSDTLKPVQLSDSPSGGHSGGMNRFASTASTSTTRASRGSPPPPETPIVEPGSIPGSDIEARYAAAGISGTATLNSFQAPSAAAAQRLAQYGSPPPPAQQPAAAPRPWTPTEQPDNQPHGPPTVYQGINPVQSPSPPSAASASAQQQFPMHPAFAGAAGATAAAVSPPTPAASTAPSAASTQPASSGLQVSVLEQDFQRMQASTPPPAYTPSGAASGYPKEKQQQGAAANVPASGQAQAPAQAQPAQQNPGQHPALSGYSQPPAAASSSAAAAVAAATAASGFATVNHPAQPQQSQQQSTTAAAAIPNQPYGNEKASAYSAAASNPLASPVSINANHPAFANDQRPESVMSNGGKPPLSHSLSVQSPAEPPPLPEGWISHLDQNSGQYYYIHLATQATQWEFPKGPTPLNHDPTPLSPATSTYGNPLASPFMKQSMASPMYPPTPGYAESITSMANSTATGFMGPPPSAGVDMYKIAPTNGVYYGPYLRYMNMDVEKGIWLGSIMIVTDGPQPPTIHIHQSVDLSPNPRQLMPYTIYTHQRWSFYKYDIDLQMSEHGTERWTYAVTSHLGCTRYEFVVAGRHEQGWRFLAHSGNDFSPLTSQADRNKLGGVDFMWKDVLQKNVECGGFHVQLGLGDQIYADRLWREVPLLQQWLAISGRENRKNVQWTARHEEDTTHAYFHYYTSHFDQPFLREAFAQIPHVLQVNDHDIFDGFGSYPAYMQQTAIFKNIGRIAIEMYLLFQHHTTIEILRNVHTDQDLFTITGAGWHFVKYLGPAMVVVGPDCRSERTQTRVLAGPTYQGLFPKVALLPPSVQHCIWMISVPIVYPRMETVETLANTLQTGKKAVNTTYNLLGKVTSSVAGVVGGKEVVQQGFSSVKKAIGKSGLMGNYLNNFGDIGITEELRDLWTHESKDLERTYLIRTLQGIAQQKGIRMTFLSGDVHCSGAGLVHDPSHPSDHKTMYQLITSPVVGAPSSNYLLKMLHNNKLLYVPLNGHMSNNEVSDTKEDMMEIFQVDASGQPREYKKLMNRRNYLAVVAFDPEAIAGTTYAASIVNGQQGLSKLSLAVDYVVQGDGGSFSAPTKYGPVIVPHLEFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWL5</accession>
    <name>A0ABR3YWL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF27">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE FAMILY MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="5">
        <location>
            <begin position="458"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="673" mass="73864" checksum="264B9849C9B5D071" modified="2025-10-08" version="1">MAKTSAALLQDILDLVVPATVRVSPDGKHVAYSACPKLNHRKADLAVAAIWIAETATCKSARRFTDGLYYDYMPEWSLDGLSVAFLSNRGNGSGSDDTPKRTCAIHLQNRDSLVSRAVTPLDRFPSISKMTFSPDGKSIAFVAPRKSEQREKGNDATVWGQGEDFQHLWLLDVESGRLRVLFDGDAHVDDFVWCDGGDELVALTHRSRHADSKYQHGTTLTVLRVADRRQRQLCHVPSAVWSPVWLGSTLYFLTNNIPEQDTSGMAVYRVLGGGQEQPLFEKVAHGEVDCAVGLVRAGNDLLVHVEHGVEEKLRLLLGGQTLVAQKKHIVNYDVSGSVQDLCIVLSRGDVNHPTELFSLDSSTGGVLQLSDHGRTLADTTFGHCHFLACPTLDGEEVLDGLYLVPSQCAGGKRHADGRTRPSTAPAAKLPTLVLVHGGPYARATDAFDAYNPLYLLIQPLLTEGYGILLPNYRGGSSRGQHFAGYARGGMGVYDEPDIVAIVQHAIDRGYADPARLVVGGWSQGGYLSYLSAVRNGAHGLGWRFCGAIAGAGITDWDSMMLTSDVGARYEAQFAGSTPWNTDKTDVRTRSGSALWEFKEAARHGRIPPMLMLHGEKDDRVPISQAWGFQRALDEAGLPFEFVTYPREGHVPRERKHLEDLTERMLRFIRDRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWU0</accession>
    <name>A0ABR3YWU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Steryl acetyl hydrolase mug81</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mug81</name>
        <name evidence="8" type="ORF">Sste5346_007169</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18020">
        <property type="entry name" value="DEXHc_ASCC3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18022">
        <property type="entry name" value="DEXHc_ASCC3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="309"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="538"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1170"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="1378"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1934"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1940"/>
            <end position="1951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1959"/>
            <end position="1971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1972"/>
            <end position="1981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2036" mass="225436" checksum="F1A91A7C20DE20C4" modified="2025-10-08" version="1">MASISPSSDEEQWRQKLAAMTDAVAALKLPPTSDVSDLDEYDDSDDSDGYYSSASGGGAQDIWDFISDDELEELGLAPSDVGNYGRGGSGGAAGSSSSYTPAWLSTKCLAMASRSSQVAAPIPPDVLQVQIMDVLQSSRPEEELQSQLTDLVGFDDLDFVIELLSHRDEIVSAAMAEDEAPAASLDGPSVGGSRLLTKAQREEQLRQKDFEHKTAVLNAASAKEAEYPHVYKAYHAGNSLSVTGKRYALPTGSTVREKEKYTEYYIPAGSKGKLGPGQSLVKIADLDGLCRGTFKGYTALNRMQSLVYPVAYKTSENMLICAPTGAGKTDAAMLTILHTIGQYALPNPVDDATVNDFAVDGEDFKIVYVAPMKALAAEITEKLGKRLAWLGIQVREYTGDMHLTKSEIVRTQIIVTTPEKWDVVTRRGVGDTELVQKVRLLIIDEVHMLHDERGAVLESLVARTERQVESTQSLIRIVGLSATLPNYIDVADFLKVNRYAGLFYFDASFRPVPLQQHFIGVKGKAGSKEGKENLDIVAFEKARDMLEQGHQIMVFVHSRRDTLATAKMLHEKATDEMCLDLFDPSNHPRYEAAVASMKTSKARELRDLLPKGLGIHHAGMSRSDRNLMERLFGEGVLKVLCCTATLAWGVNLPAAAVIIKGTQVYSAQDGKFIDLGILDVLQIFGRAGRPQFEDTGIGMICTSHNKLTHYLTAVTEQLPIESRFSAKLVDNLNAEIALGTVTSIPEAVQWIGYSYLFVRMRRNPMAYGIDWAEFAQDPMLVQRRRQLAVQAARTLQQSQMIIYNETTDELRSKDVGRIASQFYILHSSIQIFNSMMRQHATEADVLQMIAKSSEFDNISSRDSENKELSKLKDTGTVCDVGATIDSPQAKTNILLQSYISKVQPDDFALGNDLNYVAQQAARICRALFMIALNRRWGHQCLVLLSLSKSIERRVWPFEHPLAQFDLPRPVMAQLDEKGTVASIESLRDMEPGEIGSLVRNHGAGNKIARILNNFPTLTVEAEIAPLNRDVLRIKLYLYPDFRWNDQTHGTSESYYIWVENSETSEIYHHEYFVLSRRKLHDDHEMNFTIPLSDPLPDQIYVRAVSDRWLGAETVTPVSFQHLIRPDTESVYTDLLNLQPLSIKALKNPVLEDIYAQRFQYFNPMQTQIFHTLYHTPANVLLGSPTGSGKTVAAELAMWWAFRERPGSKVVYIAPMKALVRERIKDWGGRLAGPAGLKMVELTGDNTPDTRTIQDADIIITTPEKWDGISRSWQTRNYVRKVSLVIIDEIHLLAGDRGPILEIIVSRMNYIAASTKVPVRLLGMSTACANATDLANWLGVKQSQGALFNFRHSVRPVPLELYIDGFPDMRGFCPLMQAMNRPSFLAIKNHSPDKPVIVFVPSRRQTRLTAKDLVNFCGMEDNPRRFLHMEEDDLQANLARVKDDALREAISFGIGLHHAGLVESDRQLSEELFLHNKIQILVATSTLAWGVNLPAHLVIVKGTQFFDAKIEGYKDMDLTDVLQMLGRAGRPQFDNSGVARIFTQDAKKDFYKHFLHTGFPVESSLHTVLDNHLCAEVSAETIVSKQDALDYLTWTFFFRRLHKNPSYYGLDILPEEQQENGSMTAQHLANEFMVDMVDKALNDLATSKCVEVYPNGDVDPTPLGKIMSYYYLSHKTIRHLVRHAKARASFLDVLSWMCHATEYDELPVRHNEDLVNTELSANLTFPGTSFGLPMWDPHVKSFLLLQAHMSRITLPITDYVGDQTSVLDQAIRIMQASIDVLAELNHLSSCLEMITLLQCIKSAAWPTDPPVTILPGVDGEAAEVYGKSKGASMTLLQTVSAMTEAQKKQLSKSLQVPASRVNQFNRAVSLLPNVQVSVSPVTSSSVTINLKRLNALVDREGRMYAPKFPKSQTEGFFAVVGDLARDEVYAIKRVGWSSGPNRGGGGGRGGRGGRNDRGGRGGGRGGGRGGAQASGSGASGSSQPTARAVVQLPESVAQSGKVDVFIVSDGYVGLEYRVLSVEVPKAPVVDGIDKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWX8</accession>
    <name>A0ABR3YWX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007088</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR ASQA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="904" mass="98303" checksum="21152A792210C973" modified="2025-10-08" version="1">MDPSSPSSSSHHPPGPSGASVTSPSEASGSQPPPAKRAKRRQVSRACDYCRQHRIKCDTSVPCTNCKTRGAHCSNKDVLSATSLPDAHRQIECLRRQVAQLEQELNATRLAANRQHVGTNGSSASAAGPVSEPSPYSEGPESSVATPTGTALLSLGAPPPPSNITSITSITSAPSVQPPPPPPPPQQPHPPAIAQWDVAETDTGTGIAHAFWGGVHVSTARSPHKTWYGPSSLFYFISRLATFLDDSLQFQQPDWSENNTGNRSNKESIDNMLDVNAAGILVDGQTSASSTTMSRNRPAHAQKQAQAHVHGSTSRPSVSIQDPLAGARFLTLTQEEYFLDLYWQSYHTALFPILDESDFRQHYRSLWGKSGQERAPSALVDIVMALCLQFSVSTMAPGMRQKLIVDNDDTTIAGRWYYRRCQALLEYELESPSLSTLQCHILCGVYLCNGTFQNMSDSACSLAVRAGCMLGLHLAPPADMPLKRRELRKRIWWALYVLDSKIGMKLGRPFLLHLAGATTPPPLDDSVAVASLSGSPFAPLGDDRSWLTFHLYHSALFQVARRAHNAFYSGTQIPIPLCPDHTLWDHPESLEVHARLALTHGEAFTQWARNVHPALTTARVGAGAGGDGRPFATDGSPLDIEPFAPLWVQRQRLLLELMYHNLVINLYRPLISFEPSAFSIQPARQCAATCAHHAITLTQIVHQVLSSTNILAGWHEVFQWQWNAAMTLVGFLLATQAQTQGNHRSRDACEVYIVRESRSAVALSITVFDMFGQNFAVASSAASVIRTLCSKVDYIMNQGSLARRQQAEAQTRAETEAQVQAPALVQAPPGVQANGTNGINMPPANGNGTLDSDMITGADKHLDLSYSGLDASALQDTMLMAFDVDQWLDLNALWPDSDGVLFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXB4</accession>
    <name>A0ABR3YXB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA interference and protein silencing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="375"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="670"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1040" mass="111038" checksum="A591412E09FE2A13" modified="2025-10-08" version="1">MSGRGQGYRGGRGGGGGGRGGGDTFAYRPRGGGGGGYRGGGGGGGRGGGAVSVVTGAPPPDPAVTNLENAILKAKPAGGKVDATRPFPMRPGYGTKGVPVTLWANYVVLTAASKPELVLHRYDVSVTPAVTGKKRAQVLRIFLEDKPELAGHRGDIVTDCKSTLVSRVRLPIDDSYTGSIAYRVEGEDAVEDDGGSGLPATRKEFVVKLKYTNALPVADLLAHLSSTSASTAAATDSTTAYTDGLPTLQALNIFFNHHAKTSRDLVAVGSSKTFSLKSGSNNEWDLGSGLTALRGVFSSVRMATARLLVNVNVTNGAFYQTGPLDQLMMARTGGQGATPGNVRRLEAFLKRVRVRTTHLKDKTNRKGEVIPRLKTVFGLATPNDGYGQEHPPKVARFGAGPKDVQFWLEGNGAGSASNAPKAPKKGKGKGVPAPAPAAAAGRYISVYDFFVQTYNRHLANPSLPVINVGNREHPTYLPAEVCVVLPGQPARAKLDPNQTQQMIRFAVRRPHENQNFITNEGLAMAGLTAASNPLLKGFGLDATSRLVTVPGRVLQGPRITYGQNKTANVKDGGWNMVPQGSLPLKFMAGSTLSSWSCLYLDVQAYSTRARGFQPDELNPLLQMFRGIMQASGVTVAPPAAAKRVRLMGDGLDDPALANFMQMAASSKIQLLLIILPAAPIPLYNRVKQLGDVRYGVHTVCVVGEKIANPNRQDQYLRNVALKCNLKMGGRNQLVEPTRLGLLAEGKTMVVGIDVTHPSPGSSSRAPSIAGMVANVDGAALGQWPGVLRVQTEARQEMVAHLQEMLVSRLRLWLAKQKKLPENILVYRDGVSEGHYPQVVSEELPRLRAACKDVYPPADQAKGLPKMTLVVVGKRHHTRFYPTTVDDADRTGNTKPGTIVDRGVTEARSWDFFLQAHAALQGTVRPGHYVVLLDEIFRPKYDPTGRGGPPPGGALGVADRLEDVTQSMCYIFGRATKAVSLCTPAYYADILCERARCYLSSVFDETPEASTVASQAGGGAGLPSDQDVQIHPHLKDTMFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXK7</accession>
    <name>A0ABR3YXK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006557</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="372"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="851" mass="95158" checksum="6ECFA45C0F42AE4C" modified="2025-10-08" version="1">MAGHKHRLSRAGRDVDANPDVEPVERPGKKPRKQRPCFSCEGGTDSPTSTPVRSARPARSHPTQEGTPQPAEPSVNGDSLNIDAGTSNSAPAFLDFQNAVLGRPAEPQAQAQAQAPAQAQAQAPRTTASPQSRVDQQQATAGHTNINVDETVDDEEKSNSYGTLVMSRGGRSKYLGPTAGSEWLKDSQLHDTTTTPSITRCPSPDVDIDEVHHEQLQPPIPQPLNTSPIAFPINATAAQIRTRDLLAHLPPADEAWALIESYYRYCAWHHDVAPKPRFQETFARVYSFVTPGTAPPTSAINFQEVALVFMMMSKGTVYNIEMPTDDPSAEEWQHLSEMALVKGNFLSNNTIAGHIMAHKNFQSDKGRHDDKAWLLWGLAMRMIQAMGLHRDGARWNLPPDIVEERRKVFWEVNAADIFQAHCFSRPSTVNPDHCDTEFPSEPRFVSSEKGYFELRFELSQISFEILNMAMKARRPHYSEVTMLDQKLRKYEQNLPYYIRCRAALVAMVSRYPSPEEAIAVTPEPARRNMPLSFQQSNLCLNLCETVINLHRPYYAKALYDDTDASNATDTHASIYAPSFYCVIERCAMILAIVSDIHARYPAISTRQWNFWYHVFGSALCLGTLVLKHPTHAMAHFVLLQIDTSIALFSSLVQNGANTPRYQRNLQWLQKLRSRAAAKMAKAQQQTANQDRNMDDQIAIQRDHPVPAMAPTNGQDDRDKDVDLIGWRTRLIRQADQQQTVVNNNGNGIMNGFNMSNNTSNNNSALDTGTATSNTTPKAISGDIAMMPGQMTLQSTDDVLREFWDPIMLQDLLEGPIDPNDQHLTSLMNSGPSWWEWEYGPSAPRTSMEMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXN2</accession>
    <name>A0ABR3YXN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006583</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12520">
        <property type="entry name" value="RRM1_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12523">
        <property type="entry name" value="RRM2_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12521">
        <property type="entry name" value="RRM3_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12522">
        <property type="entry name" value="RRM4_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034195">
        <property type="entry name" value="Mrn1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018835">
        <property type="entry name" value="RNA-binding_domain_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF8">
        <property type="entry name" value="RNA-BINDING PROTEIN MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10378">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="222"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="313"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="447"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="538"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="610"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="789"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="619"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="648"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="845" mass="89246" checksum="1F1D295388AF0920" modified="2025-10-08" version="1">MQDISAPVSQSGPNGGRFGHASKPSNSDTGFSHGAFTSNISGFGDRHPRRANIPSINTQPMNQPPPPTTTAAAPDMTTPGTAFDMQFTSLLPSQLLLGSPFQPGTPAAFATSQFQGQIGYQQAQQLQQLQAQQQQQQQQSNGQLNGQANGQQVGGQQSPDQQNMSPQAYQTIVSPSTYGAPQFYSPQSPNGAFNQLGGQIQVPMQATSPVALSPGVVSGTSRTVYLGNIPADTPADELLSHVRSGQIESVRMLPDKNCAFISFLDASSATHFHSDAILKKLCIKGQDVKVGWGKPSQVPTSVALAVQQSGASRNVYLGNLPDEITEDELREDLGKFGAIDTIKLVREKNIAFIHFLSISNAIKAVTQLPQEANWQSPRRVYYGKDRCAYVSKTQQQNAAQYLGIAPGYANMLTGADRDIISNALAQQSVAAAAVATTAGGISNLGNRTIYLGNIHPETTIEEICNVVRGGLLHHVRYIPDKHICFVTFIDPTAAASFYALSNLQGLMIHNRRLKIGWGKHSGALPPAIALAVSGGASRNVYIGNLDETWTEERLRQDFTDFGEIELVNTLREKSCAFVNFTNIANAIKAIEAIRSKDEYKKFKVNFGKDRCGNAPRQLQPGSGNSNGNADAQSPRNEGSRIASPPPNGSTSQNSGSPTNATSPGNNPNQPAVTLFSSTNNALTMYLSHVSQQAAQQQQQQHQVLVAQQAALFGTAASPSSELTLEVPQGPILSGHQQSASMSNGYANGAGAGGGAQTANGTTTIGGLLAPGNPRGQHNRAVSLPVLAPGFENGGTSPNSVPGGNGGQEGERRGHQYQASFGGMGAGFGLAIQSGLNGWVEEEVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXV0</accession>
    <name>A0ABR3YXV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="880" mass="95597" checksum="4AF97BA603441A15" modified="2025-10-08" version="1">MAPRSASRCCRAVRIHLASPSASTTSTTSGAQIDGIWITDLVLASAFAHYCRISALPASTTTTRRFASNVPGPLESRRRLGKRQMTDQLSSQLSLGPGGPLLPAWGLPNTPDLREWTWSPPRSVQELAGQDQNENVVLSRKVQDKSNLGRRRESSASILPAWLTGFGGEPPVAEATSPADSIEPKQRSIAAQLLFTKLQAWNESMPTLSERNFSRQLDDICRELQSHIGLAAMTVDESHEAVGLVWKGLSEKGKESRLAFENNAFKLYAAVLEGIRSCRLLNASDYGTAFWRDLYVYVSQLLPNSSSSISGSSPRVTAMALDTLLATPPQFLAAVADLLPPQLCAVFANQNVATRTGTNAENNAATAASHVLTRAQVQEIAEALEHIDLGQHDNVIDATTELLVAASGISAKNHTTTTVCGWLLTLAHMPSVRQDCLFKAMSQLQSSASQAPVETTQAATTAQTTQTTQTTQAEPVLAATDTELATAHTNHLELCELLLTQWISRGYVTQQVQRSFEQTMAAIDSFPQPVLDDVEKAHNKGDNGNHPGALAALALAVFWPKHSRGQCVALYVSLLKGLHETLGRDAPDVLVASLNALLAHMQAASQSGASNPGLPTFPPNTFYESLAWAADDLETAIHLHDMYASIIDLQTPPPAQPYWNISFWDKFAGQLAAALDAGKLTPGQVCHVLDLLPRSKATAGQQAMRSKSISKSKSKSKATYKPAKELGEDTVTLIEKLAVHFALAPNMAPRRALRGVELCRGILTSNAGRKARLALKESLPLPTTSLSGPLSSESLFSPTVLRALFHLVTRDLDDSMPGRTSRLKWFLAIVARERGIKAATECERALVRWRDAVKKHNKNEGIRIREEERELLEHMKKSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY11</accession>
    <name>A0ABR3YY11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006447</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="52"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="512" mass="56947" checksum="1A50048B25B899F5" modified="2025-10-08" version="1">MGVDEKPSATVVPDASMPQLTQDITHEEAALDKTDTVNDDQAYKYLASHNTAATPDEEKAVLRKIDWRIIPLLMATMSTAATYGLIQEANLVGQEYSLLITLFYIGYIAAEYPSLYLMQRFPTGKYITINFVAWGIVLACTGAATNFAGLAVCRILLGIFEAPLNAGMIMITAAWWKKEEQPRRLGLWYCSAGFINIAVVLMFYGVAHIHVGNMFAYQWVFIICGLCTVLLGISLWWLLPDSPMECTFLNEREKSVAVQRVKENHTGIKNAHQKKYQIVEALTDIKVWLLALAVFFQNMTNGLQGSFTGLIIKGFGYSTYKTILLQLPINAVVGISCLVVTWFLGSSWGQNKRIIMCIICYIPGVVSTALLYAIPVNQNTLAVHLFAVYFMNTITTCASILYSLLASNVGGYTKKSIANTMVFISYSVGNIVSPQAFLTREAPRYTTGVAVTLASFCAAIVILCILYVLYVAENKKRDREATNQPVLTEEERMHMAFADMTDKENSMMRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY29</accession>
    <name>A0ABR3YY29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="2">
        <location>
            <begin position="90"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="346" mass="39815" checksum="89C5153B13BFA162" modified="2025-10-08" version="1">MAGISKDGSGKLGRQWVWNRTLTDDIPSLPIVRGLFVTLRFYRVISHKFLASVIVKKLPNLWDIRIEQWTWLDLKGLMACLGQRNWPVWESIRSLSLYHEPNRWRGHRNQQDIHSSEHDSVLDNEFLPRFIKASRSLRELALTGTITAADFFMEAANCPREYSADDHKPPYYFPNLTKLALWEPELGGDGDENSSMTGTILSLAAGVALQMPKLRIMELWNAKKPYIFRYEVTPEQARIIVLAPFRARPEIESEWELASHHHDHLKNKPLVIKYENLDVVGVNELATRGADIFGHLRLADEILDPRSQFQLHCRNISRARFRELNGDNDEAGETDYDDDEADGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZA5</accession>
    <name>A0ABR3YZA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB5</name>
        <name evidence="8" type="ORF">Sste5346_006607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020608">
        <property type="entry name" value="RNA_pol_subH/Rpb5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007129">
        <property type="entry name" value="PRK09570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01110">
        <property type="entry name" value="RNA_POL_H_23KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="7">
        <location>
            <begin position="14"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="6">
        <location>
            <begin position="162"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="235" mass="27071" checksum="987AAF1564EE454F" modified="2025-10-08" version="1">MSFPTGEEDPAKQRELRKLWRAWRTVHEMCQDRGYELADEEVKMSFESFLNQYTLPDGTADRGKMQFSARPSDAMIKKYTPPPTAARPDPVQECGTVWVEFMTEPQIGVKEIKRFVQHCDEHSFRAGIMVTQGALSAQARKVINATMKYTQIECFMQDDLLVNITQHELVPTHVVLSKEEKTALLARYRLKETQLPRIQQKDPVARYLGLKRGQVVKIIRTSETAGRYASYRLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z088</accession>
    <name>A0ABR3Z088_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF33">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="304" mass="32080" checksum="F26D6F2EDEA74806" modified="2025-10-08" version="1">MSEITITDSMLGDVGGKVAIVTGGASGIGEAIVTALADRGARVVIGDVNTAAGQALEASLVASKREARFFEVDVTDWPSIRAFFSSAADAFGGRIDLVFANAGIGERNTVWTDLLDEGGELAAPDFSVIDVSLRGAVYTSKLALHYFRKAPSTDAFDRGLVITGSTSSYNERPNLPLYSAAKHGVIGLMRALRHVVAADPVEKIHVGAIAPGGTETALFPSRAADAFRAQGIPVNTASSVATAAIYLATNATTNGHALTILGDRFTEVEEAITRTQEQWYGQYNTDMARRAASVRLDMLSVIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0B3</accession>
    <name>A0ABR3Z0B3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pH-response regulator protein palC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006253</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037505">
        <property type="entry name" value="pH-resp_palC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463:SF1">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="455"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="518" mass="55502" checksum="2CF516520AEE77D8" modified="2025-10-08" version="1">MPYPFVLPTTSAFVFTAGLACPTHPSLLRTASTYRGVVRDTLKRHKRLPPESQSANLGLVVSSLQDYLPYLFAAADGLSGRNRDIQVTVLAQQKGDNAGKLKPSKPSSTGSSPAPAASGSGPRIEWRPVLAEARLPGKEPPRVHIPLSPTALDAEVAFTLAALGHAYTLQARAALQPLYVVTSVVPVGNQQRQAAINTATKHLLTAAGIFSYAATFTESSRFTPPVPEVSSSTLRSLAALALAEATLMAVLKDDPYPAVVAQDRNEHDREWMYKAPDLPKVRAHLFARLCLAAAEHAARAASGVSSSQGVSRSFVRYLQDLRHTSRAKACRFFAIDADLGGQTGTALAWVHAALQELGGAEGRASGAASSSSAAVSDKKGLFDRLKKDRAEKKEKKEDRRVERGLGWGGDAGRFEETRVLAMLDTKWTKQNDTINTQRIPPAAPLLAQMPSGREIHTVQPMNPPQLDPTDLEAMRVPPDPLDVLSDEVDNVALDSSEDEGEGPPTAGRQSASTPSPYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0S4</accession>
    <name>A0ABR3Z0S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF6">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045124150" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="45"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="39483" checksum="D7C0BF9D9D8BD3F7" modified="2025-10-08" version="1">MLRNAALLALAAFAEAAPQFGGGGGGGGTTMLRFGCTQTVIDRLDPLVNPGQLPSPHVHQVVGGNAFNATMPPTDISKIATCTSCQFSEDFSNYWTANLYFKARNGSLIRVKQGTAALQFNDKFSNQINGGVLVYYVSAAPGKITAFKPGFRMLVGDAGRKTPLPSNMKMQNCFRCYSGPNFGGDTAAPCQGGAMDTTEFPQKKCYGVRSNILFPTCWDGKNLDTPNHQDHVAYPTSGPATFLSLGGSCPSTHPVRIPQIMLEVVWKTDEFNDQSIWPADGKPFVFSDGDKMGYAQHADYVFGWKDDSLQKAMDTGGCMGARCGSLKYQTIDQARACTVKNMVKENVDGWIQELPGDDAAAMNMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W7</accession>
    <name>A0ABR3Z1W7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein Rho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RHO1</name>
        <name evidence="4" type="ORF">Sste5346_005763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="196" mass="21993" checksum="170804CCCB7F7988" modified="2025-10-08" version="1">MAEIRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRYDPKTIEELRKTSQKPVSPEEGEDIRKKIGAYKYLECSAKTNEGVREVFEHATRAALLSRSGKRGSKKSKCTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X6</accession>
    <name>A0ABR3Z1X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005778</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the velvet family. VeA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF14">
        <property type="entry name" value="DEVELOPMENTAL AND SECONDARY METABOLISM REGULATOR VEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0749">Sporulation</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="10">
        <location>
            <begin position="23"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="224"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="350"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="596" mass="65700" checksum="9A9B4EDABE957C8B" modified="2025-10-08" version="1">MVAPTITAGHPEPVIVDRVTRGGRRLWYHLEVIQQPERARACGAGPKSSADRRPVDPPPVVELRIFEGPSMEHAKDITFTYNANFFLFATLEHARVLAHGRLQPPSAATPPVLTGMPVSGMAYLDRPKEAGYFLFPDLSVRHEGRYRLTFNLFEQTKEFADLDKETHDGAAHTPESFDWRMEVKSNDFMVFSAKKFPGLTESTALSRTVAEQGCRVRIRRDVRMRRREGKSSTTAVAGSGDVRAEEEYARRHRTQTPEVVTDYRARSMSTESVNRTPYVPDANHAQRRPSMSDHYHSAAPSPQSGPSLPPAFGASSGGPHMSSSAHLRFGSNAPSSFAQPASVPPSPTTYSAPAHSYAQPSQPQPQQQPQQSPQHTQHHSTSSFSAPSPAPSHANTTSPPPNPSHSYYQDRPASQHYTTAPPPPPAAAPAPSPKHESFDYHRRVSNSYTPAPLAIEPANDRRDSRMISPAESKTLTLPSLSEMISFQDEKRQARPRRLATTTPPPPTATAQLLLPQPVLSHPSAPTSQSSSGPAPQKKRSYGQYNNMDPVAEAYATNTAVKNHARQTEAPRERDFEQLWWKRADGSVWTAHGEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z214</accession>
    <name>A0ABR3Z214_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046422902" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="40"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="282" mass="30087" checksum="4858D187C0F5773C" modified="2025-10-08" version="1">MNARSSLILILLLACHGHAAAVVATPVQSLPVLENAANIEAFEAAPTTTIIPNNSFSSQSAFDASWAYNYPWGTDHNGAARMDKSQSKLDPASNTLTMTAKRVADGSQKPAKQGGKTIAIHYLAGTINARQHITVGKGTTVELAGEFKAPVARGTWPAFWLTAVDGWPPEVDLAEWKGSGKISFNTFNTSSQVAAKDVAYPSPNEFHAIRTVLWDENGSDVGVKFYMDGKLVTTQVGRGFTGKAMYLILDLQMEGSSGSPGPTSDTEYAARGVSVISYKTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4A1</accession>
    <name>A0ABR3Z4A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="7">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_005270</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="11">
        <location>
            <begin position="82"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="270" mass="29798" checksum="C95800E4679930EB" modified="2025-10-08" version="1">MADSKPAPNGTALTTEQLIAELGVVPTPKIAGDWTVDKATDAIFGPESKPAPSTTSPLPYFHLLELLKTTKREGWRRFGITYGESIADHMYRMSLISMLAPPHLAATLDMNRCIKMCLVHDMAEALVGDITPVDGVPKPEKSRREASTMDYITGTLLGKVGDPSGAVGREIRAVWQEYEDSQTPESLFVHDVDKMELLLQMHEYEKRGEGRVDLGEFAYVATKMALPETRAWAVELLQEREALWRSRGLAKPAADDARDGGKEGKEGNRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4C8</accession>
    <name>A0ABR3Z4C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="2">
        <location>
            <begin position="832"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="925" mass="101393" checksum="439942802CE5A74F" modified="2025-10-08" version="1">MGYPPPGMSPAASSPPPGMGPGMGMAPPPGMHHPPSAQANRPSYGGPVGGPPGGGRGYGAPGGAPPGPSGPPGGAPPIRFAPAGPGASSLPARPNIPTGPSGYNNGIPTGPSGGRRGDDTPLSAHSNGTPIRPDFGRDRFGGGDRYGGERDRGDRYGGDRGDRYGDRNDRYDRERDNRDNRDRNDRGDRNDRGDRERNGLDQARAAMRDTMHSQAPPTNDEKLRTIFVHKVPSVGVGGEAGLQQLLGLVGRLRRFDAGTSHLEDSKVNGTGKGKDLLFAFAQYEDANALASAIALLKNVYVPVEKQEYKEDKKEGKTDKEEKDKDTEMNDGDDEKKEEEEDKEEKNDEDDAAPDSDSPYKGIKKTQLQVSVDPVSLQYIEAFEEKQGDDAKADANAKQEALRPIFEKAIHNLFFPPKIDPAAAAAAAAAASSSGVNANGDVIMKDIHGIPILTGSSLDLEALNIPLGGGGAATANQEDELADVPAEMREMVASEIASFRDRSTQRDLERLKREQEMEELERRRNGEDNPSASGPSRLGRLESSGASTPAGPRSGVHASRAGFVNGGRENGDRDDHDRDRDSRRRREPTPDTDASDDELYRREQRKTQADDDRAYSEAERKWATRERQRAAALEREKDRERAEAEREARYRTEALERDASWDDEREASRKNVLYYRDHAAWLRKRAHDRADEEARDAADRRAEQDETRKQAAAMEAVKGQADSFLDTMGGAAAKEEDKKKEEAAVAAKDEAVAKVTISFGAAAQRNQAQRGTATRRTVAEVEGLLDDGEHEGAVKRQLVPIKFEPMAASARMSDEEINEAVRSLVQEIPTTQEGLWAWPVEWKYMDDAVIKDKLRPFVEKKVVEYLGVQEQFLVEVVEEHLRKHGGPQELVEELQEALDEAAEDLVKKLWRMVIFFTESEKRGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z718</accession>
    <name>A0ABR3Z718_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045874197" evidence="2">
        <location>
            <begin position="24"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="279" mass="28838" checksum="31BFE50510373FCE" modified="2025-10-08" version="1">MGFSARFLAAGAAAASFIQLANAAAGCSSNNCLRAIIANAFTTRHGVADCNSYLATTIIYPTSTVDVTVTIVATTTTLPSVVGTSTDLSSTVSTETDTDYSSVTSTQTDLSTQTSHTTLTSTTLSTTSTTTSKTTTTTKTTTTIKIFGRDIPESTTTLIPSSIPAYATACTTSSPAWAYSSACLCAGGTATIITSQPVTTCTHTEYITETSYSPTTDVVKSTSTSATTTATTVVSTKTVVSTQTVPTIQTDHTTLTQFTRATTTVTVTKTVTSYTVKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z752</accession>
    <name>A0ABR3Z752_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="230"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="727" mass="80591" checksum="1729F587EE72A5C7" modified="2025-10-08" version="1">MRSGAIEHLNHRISTLEKMFLGQGVLWQQVANCLGQVQSKGSSVPKDFVQTSQNLHDYTAKLRTTLLSLADAPVADGESQDKNDDIPPNKRQKSDTNTNARTLNAATISTTTPSIDLPDDLQSDLVNIYFQRLHPWIPMLHEHQFRQKLASPDPKQRQRLVNILYAITSLCIRFSDDVRLGASPESRTHLAKTCRDTVILQSMQSFSVENLQALIICAFDTISSGQSPSAWSIIGSMTRTVEQLQLSVEDEDQPQARPQPRGKATVNVLIRRIAFLPPARDWVELEERRRVFWNVFLMDRFCSIATGWNLSLTSADVKRRLPCEGALWEEGRIEVPTPYFGVSEPSDGAGGEPPTNGDSLGAFAYCIEATESLSLVTSFFLQQGLDVTDTQSVQLWLMRFKQLDLRLVRWKLFLPERWRDANSRNADNNLDPNLVVAHITHNTAVVLLHQGIAYPSEEWRSVLLRLPSPSSAETCLAAATEVAAIATHVLREKTDLLTNPQIAFCLFICGRMVLAHSKYYRLPTLPAAFDSMTDSLWEIARRWRGTLASEDGNQENLASKFASRLAYAKQMGASLDIRQAAYSEDADTAVASTTTADHFSSTVNNNSMAYAAPISTQHQPRAFDSPDNDMSLAFPPLPLAFQSGPINANSGNVTMDNGTTSASAFDSIQGSMQSSVYGQPTAITDYSSSVSVGGIDRDKDMLEDLNSFLDYSFLPDQRVSIYTLPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z795</accession>
    <name>A0ABR3Z795_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Sste5346_005164</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF19">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046027983" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="20"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1895693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="268" mass="29633" checksum="A88D670D4684A893" modified="2025-10-08" version="1">MYSLTLGLLGLLAAPLVRAHGGLANYTVGDPPVWYRGYDPDENSTEQDGQPWMVQRKWASIDPIFSAADPYLACNKPGTPGPAYIPVVAGQNLTAVYWYWLHPVGPMSTWLAACPSLEKGGCVGVDVNQLDWFKIWEAGLIPGTGNLAEGIWYQKQFQNWDGSPDLWPVTIPSPLKSGLYVVRHEIVSIHIENKPQFYPECAHLNVTGQGTELPPTSFYKKFPGAYSVDDPSFKIDIYSDAMRKTYNYTIPGGPVWSGLPVDKYCLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7D6</accession>
    <name>A0ABR3Z7D6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor TFIIF complex subunit Tfg3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tfg3</name>
        <name evidence="4" type="ORF">Sste5346_004932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16905">
        <property type="entry name" value="YEATS_Taf14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016665">
        <property type="entry name" value="Sas5/TAF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23195">
        <property type="entry name" value="YEATS DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016551">
        <property type="entry name" value="SAS5/TFIID_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YEATS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="198" mass="23124" checksum="4245A0B251C365F3" modified="2025-10-08" version="1" fragment="single">MEGYPMKEWTVEVYILDEAGKEKPARCFQKVVYNLHPSFENPVQTFHEPPFKCTNEGWGEFEMTIDCYTTEKGGKQSILHDLNFANPTYENIHTIQFKNPSQALQAILRETGPLPTDEDRKARKVQDTTTKKKKTYDLEKMADVIPRLNEDDLLHIIQLIHDNKNDDTYIMNNPDAGEFSIDLYTMPDNLCRVMWEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7N9</accession>
    <name>A0ABR3Z7N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="25585" checksum="D46B09610FD941FB" modified="2025-10-08" version="1">MTITIHDGLHGDDDELGTIHYTWLANTTRDWAAFVRSFLHSCVLHREHHVRHAPAVRAQHGLREADTFFDDLRMRYLTIVQKAHGPYRRSPYTDIATLARRMPANEIAFDRAVYDIFFGGPRAADRPQQIIEQLQPHCDLLLSGTPVRPSWEETTEEKRYKASLLASIEIVAKAVGKVSQQLLLCCEKYRVNSTSLSVARDMVNLEEDDDDGKFSDLDYHFCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7U0</accession>
    <name>A0ABR3Z7U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclohexanone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="69047" checksum="7BA081A4D5BB4AEA" modified="2025-10-08" version="1">MASPPDPPIMLIAGMPDPGPIPASDAPHENQWYNARDFDGYRVTEAPVFPRGENRRRLRVVCIGAGAAGIQIAYKAERALQNVDLQIYEKNGDVGGTWLENRYPGCTCDIPSHAYQFTWARNPAWSAYYASAPEIWQYLKDVTTKFGLEKYMQFHTRVQSAVWDEEAGKWRLKLTRTGPKTSDLTTTSEARPQTSASEDQEEDFEDECDILVGASGILNSWKYPDIPGLDTFNGKLMHSAHWDGTFDLSGKTVAVIGGGSSAVQIIPSIQPTASKLVAFLRSPVWVTTGFGAKYAGPGGTNFQYSADQIREWQQDPAAYDRYCRDVEGELNKRFNLMHLYSKDQQSARVLIESIMREKLGSENQERGDKLAGHLVPPFAVGCRRMTPGSDYLESLTRDNVTVVNDSAVRLTETGVVDAQGNEYPVDVVVCATGFHTSFAPPYSVTGQNGTDLKAQFGDEPRGYLGITVENFPNLFLLTGPNSPASHSSLLPILDWYTRYLFQVIEKVQTDNIKAMAPKPAAVRDLYNHTHELMKRLVWSSACRSWFKNGRTHGPVTAIYPGSRLHFFEVLKNVRWEDYEIEYGGNGNCFQFMGNGFTEVEADPKGDPVWYFDDPFVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8K1</accession>
    <name>A0ABR3Z8K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA-binding transcriptional regulator ume6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UME6</name>
        <name evidence="9" type="ORF">Sste5346_004643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF12">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="752"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="797" mass="85949" checksum="BF014ADC5755BB67" modified="2025-10-08" version="1">MAVSSATKPKAASTKAKANAAAAAANADAKQKSSQMHRRSRTGCYTCRLRRKKCDEGAPLCTACKHLGLTCEYKRPHWWGNNEARRNQKDDIKMIIKRKKLSEKAASSIHTSVVASPPGLSLSSSSMPTSATFSDQLDRTRSASIDSHYAAAAFDFNSPPTSASEYGGVMTNGDSSAFSTPQMHPDFMFGSGFAPYEVDIKTERQMFVNDVPTLHESTTSTFSTYHTPPPPGTVLPSYPMAMDGSSLVVDPAIGLGMTGVPVDPQIQAGAMLGVGSEWMEQVYSERRESMTEETLAMNVFDFPHASSRQVAIEMDEGDQYLLDHFVQYVLPTLFPILEANQHGAVGSDLILPALQSNKCYLHCCLSVAAQHLKAVIGSAQAQVPAGQPGQLVPTSDLDDDIARHRYATIAAICDALPHAKNHQQVLESALALIFFQCGVGRFDDALPDIQWHQHLQAAASLVQQLDLPAQVTAATTAAPVTAVEDGSAGVSVDANTVNVATTGDATQSTPFNMTLMSWIDVLGATMQGRAPVFAHTYREKHLSPPHLSSLGLRELMGCEDRVMYLISEIACLEALKASGMDDIMLCHHVSVLGDQIGLTEIGEAPAKLPFNANGSLSPKQLSKNITAAFRLAARIYLCSLVPGFCSSQASCRGLVDKLTAVLQTIPCGPAGFDRCVVWPYLMAGFASMPGSTFRVFFADRITQMGEAAASVGSFGRCVSLLHETWLQQNVLIQQLLDDQEQRRQQRQQAKAVAAAAAGSSSPASSSSPDDDDTDILPPQYVHWREVMHMKGWDFLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8N9</accession>
    <name>A0ABR3Z8N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial peripheral inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CYC2</name>
        <name evidence="10" type="ORF">Sste5346_004601</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF189">
        <property type="entry name" value="CYTOCHROME C MITOCHONDRIAL IMPORT FACTOR CYC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="132"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="492" mass="52690" checksum="2DB25DCFDB94443B" modified="2025-10-08" version="1">MRHTVKPSLLGNVSTGTIQRWICSLQPRLQHHIKQPLTASEPTDIQSIRWQRTFSSSRPHRKLTPPQKGAPSPSPPPPPPPKTRRSPLLLLTLAVLAGSAVYWATAGSTSGSFDDNGQRRLAAGGGIGLNKETFVPFAVVAREEVSPTAFVLTLRLPEGVSDEGRTRTVDAIKAAWQHGLWSVEVKQPQLQIARDYTPLPNVDGVPNEDGTEMRLFVRVVHGGEVSRYLSRRTVGSTVDVRGPRLSFDVAARVGEAGGKETTTKGGEKQVVVLAGGTGISTALQAAHAVLGQGTSVSILWANRQADDSIGLNETGNGAAVNPVVRDIKALQSRYGSDRVHIHNFVDAQQTWITEASVRKSIEGTDGAASGGSWYWPWGKTQKKTAVVPQPDTTNPTCVYHSPRMLERMEADVLRGSPKAKKCSCGTTAESTTGQAGGKNLVLVSGPDGFIAAWAGPKTWAGGQERQGPMSGILGHMAAKDPQTFAKWQVLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8W2</accession>
    <name>A0ABR3Z8W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="28706" checksum="DC78A6294ABC1F12" modified="2025-10-08" version="1">MGREDQIEETEVLESIFADEFTKIADNEFRIAIKLDLPDDVIEATRPADASPEDEYELPVMILQVKYPDDYPDKEPSLELQPPPQQHEQHPLFSVADDKDELLAGLTETIEENMGMAMVFTIVSALKDAAEQMIVSRHEAAMKIKEEAALAAEREENKKFHGTPVTPETFTNWQTDFLKEMAEQRKRDEEQAAAELAKKSRGSGGTGGSGGTLNKDGSKLTGRQLWEQGLVGKIEDDEEADEDDSVPTGDVQKLKIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z992</accession>
    <name>A0ABR3Z992_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004828</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="95"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="494" mass="52725" checksum="F703C497613935DF" modified="2025-10-08" version="1">MANNHDQKDNFVSEAEQRSNSSRTASHSDKVQLDVVTVVDPEKALVQQTPQTENATGPLGPPVPGGGKPGGGRGGLPPNHPMHPSQFVGDTYDKRALATLLGSFCVMFSSFGWINCIGVFQQYYETHQLEGYSDSTVSWIISAELFLMFMGAPIVGKLFDNFGPRYLLLVGTFLHVLGLMMASLSSQYYQLFLSQGVCSPLGCSMLFFPAMNSCISWFLKRRALAFGVIASGASLGGVIFPVIVTRLVPRIGFAWTMRTCAFLILALLIVGNVCITCRLKPRKAGITLNEFLAPLSETPYRLLAAASFCGYLGLFVPISYIVVQSAAVGMSTNLQGYMVPILNAASLFGRTIPGHAADKLGRFNTMLIMCLFSVVCIFAVWVPATTGAGAKTPAVTIVFAVLYGFASGAFISVMPTLVAEITSDMSKLGVRNGTSFAILSIATLVGTPISGALLSACHGKFWGLQIFTGLSLMACAGFLLATRVSLAGFKMAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9J2</accession>
    <name>A0ABR3Z9J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Minor extracellular protease vpr</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_004072</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 8 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047129259" description="Minor extracellular protease vpr" evidence="11">
        <location>
            <begin position="18"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="12">
        <location>
            <begin position="163"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="384"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="14">
        <location>
            <begin position="635"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="957"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1897336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="976" mass="101849" checksum="8946BBA1EAFE932C" modified="2025-10-08" version="1">MHISLLTVPLLAGAVSAAVGGPGSQIINQAAAAKNAQIVPGNYIVEFEDGHDGQDFYNTIAANASKKMDLNFKLFRGASIQFHAPNETSTADATAQLQAMPAVKRMWPVRQYRIPEHTRHWVSDLATDDDTSSSAQLRRAADDTFSTHIMTQVDQLRAKGITGKGVRVAVVDTGVDYLHPALGGCFGPGCLVSFGYDLVGDKYTGTNKPVPSGNPPMDCNGHGTHVSGILAAQSGSNTFGITGAAPGVELGMFRVFGCEGNVNDDVLIAAFNRAYEAGADVITSSVGGPSGWVDEAWAVATARIVANGVPCTLSAGNEGSSGQFYASAAADGEGVVSVASVDNVVSPTLFSKATYIVKNAASPVANTSFGYTAGSPANWSSVTLPLWAATYDTNTTTDLCNPLPAKNVTNDLSGYIVLVRRGTCLFTIKAQNAARRGAKYVLVYNNEPGTLQVDVSSVPGIAGMAMVTADQGAGWIAALARNETVVVAMTDPQTAPKGLTNVNNTVSGGFVSSYSSWGPTFDVNVKPQFSAPGGQILSTFPRAQGSYAVLSGTSMACPLVAGIYALLIEARPDLRTNPAALQSLLSSTAQPNLYNDGTSRARLGLLAPVPQQGGGLVQVYDAAYATTLLSESSLSFNDSDHHALSRNFTITNRGHTSVVYTLAHVRAATSYTFLAGTDIQPAHYPLTLQVVDSPASLNFSTSDKPTASGDGTTITIPAGQRRVVTVSAAPPVGLDAARLPVYSGYIAINGSDGSGLSLPYLGVVGSMRSLTVLDSVQTYLGKVPVGAGTPAVGVGAQRIAPNSLFVLPMQKNLTAADGQQQLNLTDAQQAALIRANQSTSLVQANLNFVMGSPLIRADLVPVKLCSSPNTPAPALQDILGYKTLGSIQGFPVQWMSRDTFNSTWDGSMADGTYAPPGLYKIVFHALHIFGDPNQPSDYDIVETDPFRITYLQVPSAATSSGASTPKMLRRQAAACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9U1</accession>
    <name>A0ABR3Z9U1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006607">
        <property type="entry name" value="DM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21071">
        <property type="entry name" value="LARP1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00684">
        <property type="entry name" value="DM15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="695"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="849"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="930"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="424"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="563"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="580"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="936"/>
            <end position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1084" mass="115653" checksum="EBC39EA5376C59F0" modified="2025-10-08" version="1">MSGFSYAQAARGQSTPSSQASAAPTSNTMAAASQATSEKNGDSTAAVSQNGTTATSVLSSTTDSSKASARTLNHDVSASPLKVGSEAPSSPAASSTLAGNESTSNFSLDDATVHVPSSDKPSRVSTPGTRSPATDDAARKGGRKGKAAAKAAADKDGAQAAQAEDAEKEKEPVKIELAPAPLPSVNIWSQRMKEQAAKVKPSPPAATNGKSAVANASAATGSAKNKDARKQGSVSTGGDAASDANGTQSSGNAKSQARRPNESARVGGNDQPRRNAPRGARSTDKDEKLAAAARDSLPPVRDAVSWPTPETAAVSEDPKTKLPLGDNKTEAAVDNSQDDAGSAKSRKKGWLPLPFVPSVNFQTPIPNTRTSKPKAGNRANRETSKSGAATNGTAPSGNEKATTVASTSAPVDKTETDARETTKETNGSTLPTRPSTHAANSHKRFSTDASHAHPREPRKPSASTLPEKPKESAADQQTPAGKSEFVPKGAHHNTHANAANGDTNGQHHQPTHPSHTDRRPPYAGKNTNHFNSSGKDFSSQEHKDQHGPNHRERTEPRGERPGRGGFRSGRGGGASGVGSTQNNQHIGHSTYQPNGQRVPPNSYSSSTAVLPPTAAPFNPPAQQYSYGAQHNSVRVGGRNASRAQLAAQGPISYNNRLQNGMGNNNSRVQGHLSHGVMNGPAEFQMPQYTVSAFNPYMDAELVHGLTLQVEYYFSLDNLVKDVFLRKKMNDQGFVPLSVIAKFKRMSELAPSIDFIRAACEQSEQLDYVVDQEQNEWIRSRYLWNNFVMPHEDRDEEARKPGPDLRTVLFRSANRPHQTHYGHPIMNGAYPTMLQQPMFSPPAYPVNGNEMMYQSHDNGVHDYASPVSASGAEPNGRPNRSGESQLSATVPDFSPSGTTGAPTTLEDYQTYPDEQVEKLVVLVGSEADSAATGADWSDQSQVNGSGANGAKNSSDESSGQQAAGRKIGEEPYPELRARALEQRSSAKGGEVPATMKHLYRFWSHCLPDKFNVRMYEDFRTFALEDARRSSPNDFGLKQLLHYYNQVLFNSGNTRPYPAVFIPHHTEAKQLSESQSSKRVNGDSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAI9</accession>
    <name>A0ABR3ZAI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lysine decarboxylase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="31466" checksum="2C5D696D485B6EB9" modified="2025-10-08" version="1">MESGGASPMPSASRTSTPTTNATVHSNLSQVTSVDDFADPSVPKKTKICVYCGSSPGKNPVYMQAARDLARVMAENNIGLVYGGGTVGLMGELARSLVALAGPDAVHGIIPEALVRYERDPNYTSRTRAAAAQAKAEGGDTRQLVDNTNGEPATNGNVNSAPVTGNDDLAIPAEEIFGKTTVVKDMHTRKRIMAQEVLQAGPGSGFIALSGGYGTFEELLETSTWNQLGIHNKGVCVLNINGFYDGLFSWIRTSVDEGFISEGNSGIIAEAKTAEDAILALRNYQVAPSVLKLSWDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL5</accession>
    <name>A0ABR3ZAL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045399021" evidence="3">
        <location>
            <begin position="21"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="355" mass="36634" checksum="D920EA7F2C48034A" modified="2025-10-08" version="1">MLPTAHLGLALLAAIGAAVAQQDQHQQMQAHTPLAEASPHHRRQDPFAATVTSVSTSVSVSISVYTSTETSTSTATSTSTAVSTSTTTATDSTRVVPIFYLDERAFEGLPYTVLHRVCGSVAGVDADGGATTYVITTTRIDLVATTTATANGTGEATAMDEASTDSPTSTKSTSSSHHSHISPTASIITALSSWTNNATGPPSTITQGPSTFVFTGTRSGDPSRTVVNQCKLSGTSSARCNLTHVGPIWYTADANWNGTYSTYNYTWTSGDRYGFAPCTVTAGVSLLGPPTAIVAAPSSTNGVGGGGSASSWRGEPGTPRPMASLIAFLLYPELRNIVWPLLAMLGCLAGLFTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL9</accession>
    <name>A0ABR3ZAL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208315" evidence="2">
        <location>
            <begin position="33"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="333" mass="32915" checksum="8AEAEC711FD99704" modified="2025-10-08" version="1">MKTTSSPRRRQSDNRLTSLFLLALAAPHAVSALSLSNFQLITSTSVPINCILTYNQQLTGCTLSDFTLSNSRRRDSNTCSLSCQAGIALAQQTIQNVCGGSTLSGPVTTVLGVALSGDLVGLLCGGTESVSSDTTAGTTTAATTAAAALQTLTTDTTTSDTNNVNTPFVFSTLDPGAGLTTISSDGVAQAPAAGAATATAGLDSQSFIQNTNTVVASSSAGNGNGHGNTNAAPPSPPVATASLPNGAPGSPGAPGATRTSSTHSTTPTSSSQSSSNANNRNVFGGGGSPFDEAAANSGAERTAGQLAGPWTQPWMMLGAAAAAMAAGGALVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAM4</accession>
    <name>A0ABR3ZAM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="168" mass="16655" checksum="109E0A7EEEAE7FD3" modified="2025-10-08" version="1" fragment="single">MAPGQEGAPADNAPPSTIAAAAAAALAASTDDRSAQPPSSRTLGVHNILNPSEVTVHSPATVPRTSSTGNAGMDTGESRTLPRTRPSSASSPQIGSASSASSNHHGRPPQGHHAQPPPGYQIGGSNSTSRLHGPSGFASVNYGPGYGQPTSGESGQAPNTTRSPGMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBS9</accession>
    <name>A0ABR3ZBS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003887</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="78"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="572" mass="60635" checksum="C5D204A865BD4F0D" modified="2025-10-08" version="1">MKKSSVVTVKERTTSRHHQASERTPLLGDPTQDPNSGAAVVDQDQLEDDIDSEDTEAGGVASPPEDDDKVRPAGFAGILALLLVGVFAANADTSLVLATYGTISSEFHSLGSASWLLTAYMLAMCGSQPLYGKLSNLYGRKTLLLVAYVLFAAGCLLCGVADRMSTVIIGRLISGCGGSGMTSVVSFLIADMVPKREVAAYRSYVNLVTTLGRSCGGPLGGWLAGTVGWRWSFLAQVPVTVLAIILVGWRLTVPEKVFPAGDEEETTSTSRLRRIDFLGAALMCATIVTFLLPLSMGGSQLPWTHPLMLALFGASQVLAGFFCYVELRVAKEPIFPLPLLARRDVVLPYLILFLQNIAQTFMMYGVPLYVQVTHVPAASPAAAGLYLVPAVVGNTVGGLATGAYIQKFARYQRPTVVGTIVAGLCHLLTTIRWTGHTSWPESLYIFPGGMGTGIIHASTFMAITASTSDEELAIAGGGLFLSGNFGSLLGVTLASSVIHAVTSRVATANLPDRPDVVANALADVGYITSLTGRLRDGIVSAYVAGFRSNFALALLACVISLVLSLMIRERRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC41</accession>
    <name>A0ABR3ZC41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOP12</name>
        <name evidence="10" type="ORF">Sste5346_003742</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-25S rRNA processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRM RBM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF25">
        <property type="entry name" value="RNA-BINDING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="343"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="460"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="557"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="65291" checksum="6BF61A1756FC2BE4" modified="2025-10-08" version="1">MAKSKSVFSAPKKAVDPTLDALFASSVGPVETTAKPKYEPLVSAKPRKDPKPAPVKPLSKEEEEAAEESEDDDEDEEDEEDEDENEDEDEEAEDSAEEAPAPAAAGDLKKRKRKNRDENDDLESRYFDKLEKEIDDGPAEKKAKREAKADENSDVEMADDNDDEDEPIIHESLLKAAAATEGGAADSATANGQIDEQDKEKADRTVFLSNVSISAVTNKTAKKTLMAHLESILDDKAAKGKKEKKEKEGEDAEDDKEDKKDLPVLESLRFRSVPFASAALPKRASYITKNVMGATAQSTNAYAVYSTTAAARTAVRKLNGTVVLDRHLRADSVSHPSPVDHKRCVFVGNLGFVDDETVLSTNPEDDGGEMERKKRNKTPMDVEEGLWRTFGKHAGKVESVRVIRDAVTRVGKGFAYVQFYDATSVEAALLLNEKKYPPLLPRALRVSRCKAPYKTARAVERAQRKVNGKPEGAKFEGKREGGSGKREGGKRDRTSGAGTFGTTGYTPKLTAEQQTSAGRASKLLGKSAATTPLNGATGPDGKPMVFEGMRARVGGVNLFKKGKNAKKSPGARNGPPGVDASRKQVRQAARSAEWRAKKGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC76</accession>
    <name>A0ABR3ZC76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Endothelin-converting enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003964</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="11">
        <location>
            <begin position="109"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="10">
        <location>
            <begin position="573"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="785" mass="86986" checksum="E3386DB12A04F499" modified="2025-10-08" version="1">MSSSAANNGRSESSPLLGNPPGGHTADGDAEEGRIRRTYKSLTSRWTALGIQRVVIVILIISLVLLATLYPRHHKKEAAAAGLCLTQACIHAADGYLTNLSPNYKNIDPCEDFEEFVCGGWRGAHDMRADQGMTDALGLINDGVTSTIRNILEGDYPDSSDHSTFSPSNLGATVSSTDRKNFDELKAAYDACMDVDAITKEGIQPIVALIDELAKTFDTSYSASPVDYSESVLFLKKRGISSFFSFYVSDDDKDPETQIIGVSPIRSFGLPSKDYFKDKDVVSQYLSAMTKVLGAIKPSVAKIGAADKAAKALVEFESRLSLAAPDKEDMDDVTKTYNLMSVKDTSKLVPQFGFEKALKELVPSDYTLNVTVTAFPEVLANVSSIVADTPIEVVQNFLYWRLIVYYSSAVLGPEIRPWRQFQNILQGKDADADPERWRTCVNHAGGTLGWILSRFFVEASFSAAAKDFGNQIISDIKAAYLKNFDSLEWMDDETRKVAAEKVHNIDQKVGYPTESPNIMDPEDLKKYYEPVQISDSFFGNILSSDDFDNKRMWATLGKPTDMKEWGMIASTVNAYYNPPHNEIVFPAAIMQFPLFSVDLPSYVSYGSFGAVAGHELSHAFDNNGRHYDLHGRYNNWWTNATIEAFTSKAQCIIDEFDNFTVIGKDGPIHIKGRQTLGENIADSGGLTAARLAWDMRREAIKKSGKDSGVESLSLPGLDDFTHEQLFYISYGNAWCSKFRPAMLTNRVTTDEHSPDPIRIKGTVLNSRGFREAFQCPVKEPTCELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDU1</accession>
    <name>A0ABR3ZDU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_003395</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="61"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="60724" checksum="500E470B7FF813C0" modified="2025-10-08" version="1">MGSQKDVSVAENEHQEPTSVTPSHNEHNEAAAGVAALNESAIVHAVEDTTGMRDHWKCLAACTLMSMCPFQYGVDFGLISGLQAMPGFLKVFGYEIPSTDPSQAPTYGLQTERQQLISSLMILGAFISSGLAGPTAAYVSRRMCIWAAIVLCIVANVIMMTATNIGAMYAGRLLIGLANGMLMTYSQLYIQECAPAKYRGMMISAFQVWTSLGSLIGTIVDNFTAPIVGKNSYIIPLAIIFVIPGLLFFALFLIPESPRWLMDQGKYDQARKALRWLRPYSDDIVEAEATEIQDGLEAEKALNASVSLMDLIRNPIDRRRTLIAIGALSTQGASGAMYMIAYGTYFFAEAGIDAPFQNACILSGVGVVVILLNSAVITKIGRRRVFLTTGLTICAFSQLFTAIIYTVKPGSQSAGKGIVAFSVIYIVGYNGLVSSYAWLSGGELPSQRLRSLTFGVATAMGFFLAWLATFTAPYFINPGSLNWGPKYGYIWFPSCLIAAAWIYFFLPEVKGRTLEEIDEMFMAKLPARKFRQYECVGHQAHAEKSTEEKNTVEHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE63</accession>
    <name>A0ABR3ZE63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tetrahydrofolate synthase</fullName>
            <ecNumber evidence="3">6.3.2.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Folylpoly-gamma-glutamate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Tetrahydrofolylpolyglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_003471</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10580"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="Rhea" id="RHEA-COMP:14740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="574" mass="62050" checksum="5CD59FBBF1C11B8F" modified="2025-10-08" version="1">MASLSAGLHQGQGQDKSALSSLDFASLPRTYKSALHLLSLLSTNRDVTSLFETPPKDENGVPFDFNSLAIPEVVAWMARAGYKDLPKDLAPLKCIHIAGTKGKGSVSAFATAILVEAAKDNGAAVGRIGTYLSPHVVSVRERIWLDGKPIDRELFTKYVFELWARLSEAAVAADPSDPQPYGAHTKPFYFRFLTLLAFHVFLQEGVRSAVIECGIGGEYDATNILPASSVTAAVVTRLGIDHVAMLGRTLEEIAWHKSGIFKDGVAAFTLQQGPAESELDKKAAPPGESREDRDAALSVLRTRAAEKKAQALYEVPRDVVAQWPEVPDAGLPGAFQKYNMVLAAAAARYHLQKVGATDGHWVDTNDANLDPSRISENFVRALAKATLRGRCESISDTRAVPCPAEYLVDGAHTADSLGEVARFFISRQNCAGLLSTTSVLPPRSRRILLFSVRDRNPGDLLRALLAGTTSEATKTHPTFFDNAFFVFPPEAVPEREEALAVMQDISPGTVSQAFGNVTYAIGQIRALAAEPMKQTVGASADSKTAPLWPCQVLATGSFVLVREVLQELDFNFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE92</accession>
    <name>A0ABR3ZE92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Subunit of the glycosylphosphatidylinositol transamidase complex-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GPI16</name>
        <name evidence="4" type="ORF">Sste5346_003401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007245">
        <property type="entry name" value="PIG-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959:SF11">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04113">
        <property type="entry name" value="Gpi16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577688" evidence="3">
        <location>
            <begin position="22"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="637" mass="70180" checksum="E66E0B9C02ADE71B" modified="2025-10-08" version="1">MRRLISYLFCLLATYILPVAANDAANVEAAAAAASASAVTDDPDYYENLVLRPLPLSALLASFNFRSNTTVAAFEAHNFRFFPRSLGQILQYAGTRELHLRFSLGRWDAESWGARPWAGTREGGTGVELWAWLDAQTDEEADEKWLTLTNALSGLFCASLNFIDGTRTTRPVMSFQPEGDHPANTSMQLLYGTLPREVVCTENLTPFLKLLPCKGKTGIASLLDGHKLFDASWQSMAIDVRPICPADGADGECVLQIEQSIDMVLDIERSKRPRDNPIPRPLPGHELKCDTAKPYHHDDHVCFPANYSAHQDWTLNQIFGKPMRGTCTLADPETPPVCLEVPDARTVYLSEGVREVKNADGRSRCFFFGPETTFEVMLPNENANGVPEAPETAVLTPETPLLYAERSLTGHGAERGGVQTILTNPSTDTEVEFVYMESLPWFMRIYLHTLSARLVDADGGGDVIEEVYYRPALDRARGTQLEVRMRIPPGATVFLTYDFEKSILRYTEYPPDANRGFDVAAAVITILHPPSTARTAAWRSNLRTTTLLLSLPTPDFSMPYNVIIFTSTAIALAFGGMFNIIVRRFVAADEGPTVSLKAMLGKLAKKVQALAKKPKKGDAKVPEKASDAAASPSAKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFE7</accession>
    <name>A0ABR3ZFE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TOP3</name>
        <name evidence="11" type="ORF">Sste5346_002819</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="3"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="167"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="549"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="675" mass="74833" checksum="4E03829455E19F19" modified="2025-10-08" version="1">MTKILCVAEKPSISKAVAGHLSGGQYQTHNTQSKYIKNYVFSFNFGPPYGDCDVTMTCVSGHMTTLEFGPEVKDWKYPPPDHLFSAPVHTVVPDDKKVLADNIANQARYCRALIIWTDCDLEGEHIGSEIRDAARKGKPSIEVKRAHFSNIERAHILRAAHNLVGLDERQVNAVSARSELDLRIGFAFTRYLTNNLRPLGGPLASLTLSYGSCQFPTLGFVVDNYFRVKNFVPEPFWSINVKHAKGKLTANFSWVRGHLFDRACVIILYERCLAAKKAEVVKVQEKPTKRWRPLPLTTVTLQSMATRFLRMTGQQVMTIAEGLYNKGFISYPRTETDRFDKGMNLQALVQKQTQDSTGRWGPFAQDLLQNNKFVWPRAGTHDDKAHPPIHPITYAAPSVLNNEEGRLYELVVRRFLACCADDAKGMATDVEIAYGSERFRAKGVRVLERNFLDVYPYENWTDTAQLPAFSMGERFEPTEALMTQGKTSAPGYLTEADLIGLMDANGIGTDATMAEHIQKIQDREYARAVEQSGGSNNSAATGDDDDDGFGGGGRGGRGGGRGGRGGRGGGSARGGRGGGRGGQRVFVPTQLGVALIQGFDRMNFETSLGKPFLRKEMELKMKAICEGRTTRNAVLQESLNQYRQVYDQSTERLDVMRASCRQYIFNNGGTGTTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFZ1</accession>
    <name>A0ABR3ZFZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 5B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FUN12</name>
        <name evidence="10" type="ORF">Sste5346_003019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03703">
        <property type="entry name" value="aeIF5B_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003078">
        <property type="entry name" value="PRK04004.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="502"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="249"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="356"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="316"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="356"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="435"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1097" mass="120084" checksum="B20A18DD8F27250F" modified="2025-10-08" version="1">MPPKKKGGKKAQDDWESELGESIAPVNNAAPADGDVKNGDDDDEGAGGGGLMAVLRKNKEKRKKKGLSEEFEDPNAANGDAAAEEPAASLADKAPVEATMDDEFALPEKKGKGGKGGKQASAAKADAAADAVGDDDTGGRILTKAEKEKLKKEREKQRKKEQASKKKVEPVKAPAKAAPAAAAATPAAASAPVAAVPEPAAAAGGKKKKIPAHLLAIQKQQEEIRLRAEQEQRLLAEEKARLVELERQEAEEAKRKEEQRALKKQKEKERIEQLKKEGKYLTKAQKEAKARNEQKLQQMMAAGIKVGALDQPGDAEADKDKKKSKDADRKRNAGRKTKIDEEKALAEAAERARLNAEKLAKEAEEREKAAKKKAEEESAKAKAGGDSDIDDDWETAAGADTKDEDVKDSWDADSDEEAAGDKKTLPSRPKKKSGDEDDNEDEDDDEDDDSDEDSEDDSEEDSSEDEQESAAKAAEAQRKRELAELREKEHQAALAARSKDNLRSPICCIMGHVDTGKTKLLDKVRQTNVQEGEAGGITQQIGATYFPIEAIKQKTQVVNKDNAFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGLEPQTLESMRMLRDRKTPFIVALNKIDRLYGWKKVDNNGFEDSLALQNRGVQNEFAKRLEQTKVAFAEQGFNSELFYENKQKSRVVSLVPTSAHTGEGVPDMLKLLVQLTQERMADSLMYLSEVQATVLEVKAIEGFGMTIDIILSNGVLREGDRIILCGVEGVIKTNIRALLTPAPMRELRVRSAYVHNKEVKAAMGIKISAPGLEGAIAGSRLLVVGKYDDEDDLEEEVESDLASVFSRVEKSGRGVSVQASTLGSLEALLDFLKDCKIPVANVGIGPVYKRDVMQTGIMLEKAPDYAVMLCFDVKVDKEAAAYAEEQGVKIFTADIIYHLFDAFTKHMAILSEKKKEESKMLAVFPCVLNTVAVFNKTAPIVVGVDVVEGNLRLNTPLAVVKTNPNTNQKEIISIGRVTSIEREHKQIQICKKGQPSVAIKIEMGGHQPTYGRHLEESDALISMISRASIDTLKEFYRSDVTDEEWKLLIKLKPVFNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH04</accession>
    <name>A0ABR3ZH04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12191">
        <property type="entry name" value="gal11_coact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033789">
        <property type="entry name" value="Gal11_coact"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="599"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="655"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="757"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1300"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1514"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="896"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="957"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="453"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="762"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1026"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1313"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1402"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1515"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1529"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1547"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1566"/>
            <end position="1575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1752" mass="190420" checksum="018B74944B2D80C1" modified="2025-10-08" version="1">MAANLNMQQQMAMPLQQQAQQRRNGIPNHLMAIVYQQLVANTPVVNGWRSGVQLTERMGKTVNLVTNIILANPGIDWQKALQAGVDFERKAYLEMPDRAMYEKQMTTKIQEQFAKRQSNEQNIRNDMNNQQLQQQALFQQQAAQQQAAQQQQLQQQLLMNPQLRAFGQNPQSFQHLQHPMQASPIPQQTPQQMGAGGLMGQNGVGMQMAPNQQQQQQQQQQQNMQNMNQVRQTGMDLSKLTEQDRQKVNEFANRLYMSADDNTKRNLLASMQNRVSPQTIQNLQRSGKDVLMHMFQLQALSVLTQKATTLRGQPGVPNANMPGGQTPMQQLQQQALQQQQQQQNAMAAGVMNGNLMGVSGPAQGGGLVAGAAGPGAQVNGQYPFGANMESIMNEHKAALLAQEAGQVVVPASTQAGRNATPQPPMAGAQGGPNNTSGMAGNQGRPNTQQGASQPQRGGPQMQQGFNMQQMGLDPSGAANMQNQQQRAQQQQGNKQLQGQPGGVMGQSPAMGNMGTPMARQATTQGDAATLQQQQQQQQMVQGGPPFTGQLNPRFNQIPANLNPNFQNMINSMSAEQREKFSSLPPEKLNEFMARWAAQQQQRMNMAKNNPAAAGQMQQQQSRQGQMAPGQVNPQQQQQQQQQQQQQQQQQQQQQVQQQQQQQPGAPANQFGIPPQQVTGMPPQNMGQPGQGQRQMRPQHQAIMDSMDLPTQVSSQFSLPPEVKKWRDLKIWIAQNNLPDPVKAQLSNFQMMQFRQLVEKRTQQQQQQQQQGGQQQRPVPPGMQPPNAAAVAAAANANANPNANKPVGPGPNMQQMAGALPNIPASMLTITAAEVAQLRARDPKLANASEEIVRKFGARMKHDQIMKHYMQQQAKNGVPLNVLQQAQQAQQAQQAQQAQQAQQAQQAQQAQQQAQQAQQQAQQQPGAGQSLNLHQQQQLLQQQLQNPMQQQPQQQQLQLQQQQQLQQQQQQQQQLQQQQTKQQLQQQLQQQFQMQQQQHNLMMQQQGNQLDNPNAAAAAAAAAVTQPMANPATQQKTAGGAANQASAPPQTSPEQPAPAPVPATTAKTKAQQNRAAAANRKRANAAANNTADDSSNAASAPTAQVQPPQPPQVQQQAPQPQQQQQRPGMPAMTAEQFAKLTPEQQEMVRQRQQAVASALQPGSETMQHLMAIGTEVRQDIQKEQFPDIPMTPEEKDEVWKKIGETVEPLFKVGRALGRFYMATRDEVRTRKFFRTRYRLSQQFINSETLSGRKENFSITLDEIESHRNLLMDMAKEAMNFVRAHATQTQLQAGQAGQAGAQAMALQESQQGRNAPAATTAPQAQPAAAAAPAPAEETPRAPKHKRSNSKANHQPPAAPTTSQPPFPLHGASPHGQPAYIGKPSVTQETLHLPTTKRRKTNSQVTAPSPVTAQTPAATTPSTKGASPEVKRRQASEAKAAAAAAAAQSTSTAAAQQAAKALFYCTENDCDMKSTGFATEEARRTHVEEEHTKPAADPFKFVTDALSEALGLDAQGHAKTTANGASTGTNAPSMTSTASKQGLTPATPMSRVTSMNRQTSNAGAGGKAAAGKGAASNGLGTTPKASDVGLQGSAPSIDTDVLLASASLNDAWDFANVDPQDLASTFSFAADTAAQGAIADFSVYRSMITPNDTPESRTDSGWASEPTSDILESTNLDLNIDMWTTSEDGTIIPSMLDDMQKFSMQPIDETDTADLAQMFLNDGPSGFGDDETDMVSMFNKTNVELDPSLYSFGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHE4</accession>
    <name>A0ABR3ZHE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcofluor white hypersensitive protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="13466" checksum="EEC82DA631AB4ACA" modified="2025-10-08" version="1">MSRSRTPLILGIAAAGGVGYYLYSAGGNPKVAEKKFESDLQSARDRATGNTNQIRTDAQKYGAEAGAKIDSAVNKAQSEYNKAAADVQQKAEETRTNVNKSIDAFDKKVEDAAAKTKSGVSSWFGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHS1</accession>
    <name>A0ABR3ZHS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Complexed with cef1p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CWC15</name>
        <name evidence="6" type="ORF">Sste5346_002623</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="272" mass="30940" checksum="CAB2741BDB60D7C6" modified="2025-10-08" version="1">MTTAHRPTFDPARGKEAPKGPAYHQRLLPAHTQLKFRKAGQGGDADSQVRDLQAELLAAEAAHYAKIHGGPAPHSEDDAVSAAAAAKRRLITEDGTDDAEAKRRRILEETRDIDADDDSDEDDSDKDDDDEKDDDDDEDDDDDDSSSDDDSDDEDETAELQRELEKIKRERAEKREREEREKEAAEAEERERDIARGNPLLNKPDFTIKRRWDDDVVFKNQARGTDDKGKQKEFINVSPQYGAPLNSMQSTNNSKDLLRSDFHKRFMNKYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHU4</accession>
    <name>A0ABR3ZHU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SES1</name>
        <name evidence="11" type="ORF">Sste5346_002552</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="194"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="487" mass="54449" checksum="A8F63DD74CE38D60" modified="2025-10-08" version="1">MLDVLDLIVERGGNPAAVKESQRRRYADPEVVDKVIELWQDHRKTLYDATQLNAKINDIQKQIGAKKKAKENADDLLQQKIATEKQKKDMLDSAAVKEKAMNKALGSIGNLIHDSVPVDNNEDNNPIITTWVPADREVAVGEEDRSKLLSHHELLLRIDGYNPEAGVKVVGHRGYFLKNWGVFLNQAIINYGLEFLTQKHGYTALQSPFMMSKEIMAQTAQLDDFDEQLYKVVDGDSEKYLIASEQPISAYHAGQWLQANEMPIKYAGFSTCFRREAGSHGKDAWGTFRVHQFEKVEQFVLCDPEKSWEQFDAMIANSEEFCQSLGLPYRVVAIVSGAFNQAASKKYDLEAWFPFQAEYKELVSCSNCTDYQSRALDIRYGPKTQTDVKKKYVHCLNSTLTATSRTMCAILENFQTPEGVRVPEPLRKYLPGAPDFIPFTKELPKDSTSTKKAKAADKGAKPKVAAAAGAVAAKVGEAADALKNVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA8</accession>
    <name>A0ABR3ZJA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF6">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="94"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="416" mass="45694" checksum="A269F63410764258" modified="2025-10-08" version="1">MATLNVLMVGTGEYTTGFVGGGASGSDKKVGVVGLSLFDLRRRGKVGDLSMVGTTGSKFPAIRDHLQKNITEAYNGLDTSFVSYPAEGVRNPDAYKEAIDALKKGDAITIFTPDPTHFPIALYAIERGIHVMITKPAVMTLEHHVALIEAARKHGVYVYIEHHKRFDPAYADARHRATKLGDFNYFYSYMSQPKSQLETFKAWAGVESDISYYLNSHHIDICDSMVTQLGYAPVGVTASASTGVATDLGCAPQTEDTITLLVRWQHKSEPSRRATAVYTASWTAPQRAGVHSNQYFHYLAQNGELRIDQAKRGYDVADDSVGQLMWYNPFYMRYAPDEDGNFAGQSGYGYVSMEKFVDGCRAVNEGTLKAEDLDAKALPTLANTIATTAILEAGRRSIDERREIGISSEGGVWKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKY6</accession>
    <name>A0ABR3ZKY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRPL51</name>
        <name evidence="8" type="ORF">Sste5346_002494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="137" mass="15374" checksum="0CD70425E96F68E1" modified="2025-10-08" version="1">MTITAIPKVSVGRNGLGAFILQCRKLDFHYCDWAGSSRGMNQFIKQKLQQFAAENPQIEFTVSPRPSRHPVIVGHYITGRERSICVRNLDANQILNKAQLLRDATGEKNKKFSKPVSSINESVRGVWSPHHGNGFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLA5</accession>
    <name>A0ABR3ZLA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="83" mass="8987" checksum="15416EA1D8D8345B" modified="2025-10-08" version="1">MSATVASRAIGSVVSLGAASAVAAYVYGQLHTESKTMDRFFSAYHTPESEASRQRVFEGAIEDPRKNLLNFLSWNSFGANKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH5</accession>
    <name>A0ABR3ZLH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UmuC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001946</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46404">
        <property type="entry name" value="DNA POLYMERASE IOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46404:SF1">
        <property type="entry name" value="DNA POLYMERASE IOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="18"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="601"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="608"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="638"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="688" mass="74547" checksum="7B815BF0014761B9" modified="2025-10-08" version="1">MSSIQSPSAPRRNDGRIILHFDYDCFYAQVVQNRAPGGALIGRCVGVTQKSILATCNYKARRRGVKKLMRITEARRICPDIVLVDGEDLSPFRDVSKQLYRLMRDMVGPTAPVERLGLDEMFVDATALIDANLGRILAARSEKGRPRSDLFVMSDGNDGVQGFQFDSSSFTGHVIGNGTRDIQTHASSQDQHDATASEHTKTRMRLLMGSHLAAHLRLRLEHDAGYTSSSGISTSKLLSKLAGKVNKPANQTTLVSAGWSSDDVDADAEADSVVWQFMDPLPLRSVPGIGFKTSSLLSRYFYSAQDEARKEDVVEKADQEERRKGAPQKEDDEGEEEEGDEDDDYSDAPPVTVMDIRTLPGISPRLFDSILGGNNGIAGTAGAPAGNIPTGLRTWQLLHGVDDTPVKGGRDLPSQISIEDTYAGPRQGTLRPDAASAVAGELHKLATSLLRRMHVDLLDSPSTAKNANSGEAQPSWLARPRTLRLTLRPQMPRAIDNKEPSNYFARMSHSQPLPGFVLSLTMPPRQIVDRLVAGSLVPMFRKLAATVQMGRRASSESATSSTGGKAGPLWTVGLLNVCVANMAHVAGRGDDIAALFKRQDNGGVNRNETPKSSHDGLDDLNNKTEKECDKSTAASWDSGEDDDHEGDEDGWAAEEDESCGTLEACAQCGHLLPTFALAAHARFHLLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH6</accession>
    <name>A0ABR3ZLH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="287" mass="32494" checksum="1322E109E979C056" modified="2025-10-08" version="1">MTHLAEEFLNTLYKAYGEANSDGWITPPLSLHSLTFGMRYYPGADANLEALVDLHSLRAIHINNKLSRPGNTDIRFKLFGPDTCSNLRFYGIGDMTHQAFDFLTKTNPEWTRRLALVPICAHRNADRNLVELMRGSVAESRPPQRVRMMAIELPGYSSSRTESILADLVALDDGTLEGLRVLMGTGKNLEFDHLDKVLEALGKLKGLRQLILHQRWRSSTRNLLLGVIAQKAAMAIPTLQFIHIPDKSWQVHRTRVDDGERYDVQFEPLDKYEEAGIELFRVPVVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM73</accession>
    <name>A0ABR3ZM73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF18">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="652" mass="71195" checksum="BF637B6E4F5112D7" modified="2025-10-08" version="1">MPARRSVEAAPRGPSHSAPYGQACLHCFKAKCRCVSRPDGDGCERCHRLQKTCHSSEAIRKRSRPKAASPVLTSGTSDERVANIEEKLDGIMSMLQSVTQAPAPATAAALRDIFGGRMDEHLRGAIIDQLPLPPAQPTKNRPQCQHTPVSLSSPATADGSSSNEGASVTGNSAQQRPFLLRCIVAATTTLVRDKVAQGRAIKELLAKEMLLENKSNLDLLLGLLVYIAWGSDPMVSRSGTLSRLVMMAQSIVCDMRLNKPLPVDQHLLTTYTSSNEKCDEKGYDREDGAEGAVDTDQEKDTFLSEEEETLEKQRAVLGCFLITSSTSIYFAQIDGMRWTPQMDDCLRAVEAHTSCLGDFVLAYQVRLQQVVQRAIHSREHEAALPLYITQAFQTQLEELKGRRPQFPPTSPRNLDQDVQNQLWGTIFTAHEHYVELSLNEMTFSANYSPSPEAAAQTTATDGTEAAGAASDVDRVQCYWRSVHAIRALCDSLLEGVPATSFAGYSFMVWAQLSRAIVTLVRLSTLPPLAPLVEVSIDTRSVRATIDLLDVLDRFAERLKSAAAGLGRGLWLGPQRQIDDIFGRVAHLVRVLRAAVATRLEASEVGLIGDSHVGGIPGAGEGDRPPWAMVESVLAQTTVGWGDIWLEGMLPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN84</accession>
    <name>A0ABR3ZN84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="115" mass="12421" checksum="59104BE68C2DEE9C" modified="2025-10-08" version="1">MSAYNDAISAYAHAKSMADANKAAKSSSSYTTSSAASVYSDTSSYYPVKDNNMKNSYGCTPKSSKSSSLKNWTKNLVSDLGKSPTHRYDAAHSSSMHSTNAVGAPYWDNTRHTKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC2</accession>
    <name>A0ABR3ZNC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF63">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="307" mass="34037" checksum="773C6D3E018883CB" modified="2025-10-08" version="1">MSSFGPTCIVEPRDGHVHTHTAVLLHGRGSTGEEFAEELFETALSDPRKPSIADRLPSWRWVFPSSPRTWNATFVEWMPAWFEAHSLADPTERQDLQQAGLWASARYAKEIVEDEIQRLQKTQKTDGGGSDAHLRVILGGISLGGAVALWTLLGTDKPERPLGGFAVMSTWLPFAKEVRSYLMDMGTESVQSGETEIKTEPLEFVQNAMAPLLQHKQTQGTVTKAGVDTVGLSILTTPVFVGHGRDDAYVDVELGRGAHQLLVNVGFTKVEWQDYEGAEQEGHWIKEPEEMDDLVRFLEEAVGGQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ33</accession>
    <name>A0ABR3ZQ33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF2">
        <property type="entry name" value="CHY-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="122" mass="14421" checksum="B0BD671CE3E57C8A" modified="2025-10-08" version="1">MCKHVLNAQVSIRSPCCRKWFDCSECHQETEDHALMQRFEMIFACKKCKKCFRKDAREFEDSDEYCPHCDNHFVIDAVTPKQAITIESEDVRVDNRMIRDDRVKGQEMRTIFDPDLDADRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQB7</accession>
    <name>A0ABR3ZQB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123570" evidence="1">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="250" mass="26539" checksum="FDAF93C10111753E" modified="2025-10-08" version="1">MKWSSPLSALLASTASFVSANPVASRELKLFNLKILSPINANLNGRYLTINPDGSVGIFSDHPVVTGSIPPKVPVPPSVPSADTAAAKPPPGAKFYVTQAGPTGSPDASHYELHSYPIGIVDHALGLNGTAKDGIRYLVDVTNPSYNASAGSDGGNSPDWKSFTLDNYGSNNVDANGDDGRAEIDIEINLAKRIPPPMPLNGFYYGSNGHGKWVLIQRGSNTFVAAWYDGTSYVTQNYRLVDITYEPADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQC9</accession>
    <name>A0ABR3ZQC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="11">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GAL10</name>
        <name evidence="13" type="ORF">Sste5346_001433</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 11" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="12">
        <location>
            <begin position="6"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="374" mass="41018" checksum="7E9C5F693A42F24A" modified="2025-10-08" version="1">MVVGTVLVTGGTGYIGSFTSLTLLQNDYDVVIVDNLYNSSEVALDRIELISGRRPAFHKADVTDEAALDAVFKAHPAIDSVIHFAALKAVGESGEIPVEYYRVNVGGSITLLRVMERHGVSNIVFSSSATVYGDATRFPNMIPIPETCPTGATNTYGRTKSMIEDVITDQVNAQRNNAKKAGKPKEEEEKWNGALLRYFNPAGAHPTGLMGEDPQGVPYNLLPLLGKVATGDRDKLLVFGDDYASRDGTAIRDYIHILDLARGHLAALKYLKEEKPGLKTWNLGSGRGSTVFEIIKAFNTSVGRELPYEVVPRRAGDVLDLTANPALANKELNWKTELTMEDACNDLWRWVENNPKGYRQDPPAKLLEALKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQV5</accession>
    <name>A0ABR3ZQV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein mak11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MAK11</name>
        <name evidence="2" type="ORF">Sste5346_001006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="632" mass="65945" checksum="FA85C54C83CEE497" modified="2025-10-08" version="1">MQSHAPKSAMKRKREAKASAADPEAPAATRPKTKATPSSTTTSISTKPTSILKTKSALKNTSAPSAVADVAASKPKDKAARNRVKAAAATAAPTPAPAPAAAATTAAADSIVVLGDAPAAIQIVAGSYDRTLHGVVATVIPAGIKFTDTFLFNAHSSAIRCLALSPPSVPVPGQGQKIMLATGSTDERINIYNLSAHAPADASSTGLGASDEERAIMAAVTSRPVMPIAENAKNRELGTLLHHASSVTKLSFPTRSKLLSASEDSTIAVTRTRDWSLLSMIKAPVPKEGMGGGLRRPSGDTAPPGGAPSGVNDFAVHPSMKVMISVSRGERSMRLWNLVTGKKAGVLNFSKELLRDLGEGRFSTGEGRQVVWGRAFGAASDAEGEAGDAEENATDEYAIGFDRNVVVFGMDSLPRCKVLSDTRTKTHDFRYVEVDDDPEAAAADKAGLFSLLTVATEDGRILLCSTRAEDLVAPPASSTTTPTDDKKAPAAAPLPSARLIGQVGGSATGVTGRVKAFKILPVLEKAAGDKKKLQKAWYVVSATSTGMLRVWKITGQELRSAYKNSTAVSATGGPSSTSSNKPSKQLGTLLGAYQTPDRITCLESFVMIPRPDGVEDSDVEDDDDDEEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQX1</accession>
    <name>A0ABR3ZQX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="238"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="830"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="907"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="830"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="917"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="946" mass="104339" checksum="73B9686D79864E75" modified="2025-10-08" version="1">MAITEPDVGLLTSSAQIFSSNHTLPQIRAIHKTLHVQVDDKATRLRTQVGGSYRELLGTAETIVQMRTDMEGAQTTLAGMGGRCGRAVVGGKVTALASFVDHEQEQSSLSLAARARLLEACSRTVGRLLSRTNPDLSANAASKTTKASARQQRHQNRQQQQSWGERLMLASKVLVLSRLLLSGMNEKSGDVPSSKTRSKQSALQDAAVLSSIEASKRTLGSLRRRLRDIIEVVERSVPTTASEKAAAEAEEADDDDIDGANEDGGDDEDAREQRDRNRTLSAAATARDDLLRALCAHSLATTSGARDVLWQLLHVRSQAMALAFEMDDEEHQNHHQADLGQQLLDCRASWKADNVLRGLALYTKTLLDVQALLPHRLPEALLGLKRRALLDDDALRQIEGLRLDVYSRWCGEDVQYFKPYIRHNDLDATQAREMLSKWAERGSEVFVSGLQKALEQADESSTDKPRPGQPPAIRRYLDMHAIVDLRTRVLQLWIHDSSKARGFDPSELLDKMRAVFNQQMLQVLATKVGKLRLVGSEVAATLASWQDGVSDRHAQLWGNSNTDKDYKAIDTDLSEGAVSFVRDVVTRLHGRSDVVAKAVTSYITWRHVVDDVAAVVDQLRKQRWDNDMDDIVEDEDTIAQRQQLLSKDDPQTLHDRLEAALDTAFQDLNTQIAAEWAAVAKSDTISATTKGNIAMYLVRVLREIRSRRPATSSSTAVGQLGLQIIPELHAAIVRVVVVSPLEQFTSKTLTRKTVAGRGLWDVAGTSAALPSTPSPGVFRFLRDLSTAMDTAGMDLWSPAAVAQLKKQVSEQLGEQWTKLLETADYLQETAEKTNGSKDDDEKEDTSTSSTEALSADDRRDLLKQWLFDIAWLRCSVGSDSASSTTGKKDKSKKKGIAELEDAVFKRTGLSEDKEANGSGSRTPQQRISKAALDYWKKTSLLFGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH9</accession>
    <name>A0ABR3ZSH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052145">
        <property type="entry name" value="Mediator/Homeobox_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330">
        <property type="entry name" value="HOMEOBOX PROTEIN BARH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330:SF19">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="175" mass="19075" checksum="E16816143A70E972" modified="2025-10-08" version="1">MRRYFEQQQQIQQRQQQEQQHQHQNLQQQQQQHEQQHQVQQQHQQQQQQLPNGNPELHSLEDAAGEDEDVPGMTAGVGVAVGVGVGVAVNVGVSSTVGLGVADMGTPGIGAPGMSVDHSTVDNDADGENEVDEQADDEQQAKRQKMEPDAVDSTLEDQAVLTALAAHNRTAYSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTA6</accession>
    <name>A0ABR3ZTA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000657</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="34"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="443" mass="48521" checksum="F4D1AC09645B2B90" modified="2025-10-08" version="1">MLVEGVKDLKLDFAPTKKSKKLNVLDEFGKANLKRSTSFVVVGHVDAGKSTMMARLLLDLDYVEKRTINKYEKEAKIIGKSSFALAWVFDNNEDERTHGVTINVTARHFDTKRTAFTILDAPGHRDFVPNMIAGAARADFAVLVVDAKTGAFESGLRGQTHQHALILRSMGVMRIVVAVNKLDTVNWSEERYNQIVDQTKGFLRATGFYMSQVTFVPVSGKTGDNMAKRTTVSAASWYKGNSLVEELETCEPMPRPIDKPLRLPIFDTSKTAGSAITVSGLIEAGSLQVGDALLALPGNARAYIKSITRNGEPAEWAVAGQNVSLDLTNIDPLNVRPGVLLCDPAKPAQVIDSATMKVMAFEPLIPQPLEVHRGRLEKAAKIKELLSIIDLKTGKVLREHPFVVSACRVARIKVDLEKKIPLETGQRVVLRAEGKIIGAGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG67</accession>
    <name>A0ABR3YG67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_010293</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000128">
        <property type="protein sequence ID" value="KAL1887311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="11"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="523" mass="57385" checksum="F5DC6DE2A126F34A" modified="2025-10-08" version="1">MLEGYALEVTLTAANSAAQSWYGYDQGVVSGILISPDFIATFPQTKRSSIQGITASCFSLGNLLGCLLAALYGGRLGRKNTLRVGATISIIGAILQFTAFSFPQLIVGRVINGVGNGMTSSTCGIFQAESCASDRRGRLSVIVVLHNVVFYCLATWLTLATSFASGGWQWRLPLALQCVPFAFLMGLLPFVPESPRWLMMKDRTDEALEVIRRYRGKDLSSNDPAVQSEFRSIKGALLIEEQSKTSVMTVLRRQDRSGHLKRLLLGCGGQFMQQLSGINALNYYFTIILTTNVGLSDLLARILTGCNATSYMISSACCFWLIDRFGRRSLMLTGLSMQSLAYIVVAISLGLLVKAPHALGIVTVSFLFLYYAVFGCTWGMVPWVYQSEINSIALRTVGSAAATSTNWLFGFVCTQFTPTGIKNIGYRFYIIFAVFNLAFMFVVYFLYPETANRTLEDLDAYFDIDSGNSIIIPIGDKVAKSTQRPQEAIDAENTRVALAENADAKAQLKLSVHHEENVTTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGC7</accession>
    <name>A0ABR3YGC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xylose isomerase-like TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000124">
        <property type="protein sequence ID" value="KAL1887376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050312">
        <property type="entry name" value="IolE/XylAMocC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110:SF57">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110">
        <property type="entry name" value="HYDROXYPYRUVATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="1">
        <location>
            <begin position="27"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="351" mass="39266" checksum="7D98169473F01024" modified="2025-10-08" version="1">MASTTYKPAIMSASLGRAAQHDFDYKVEQASKAGFKAIEIFFEDLEKVGRDLVAKNGGDASNTAELTTEQLLAAASHCYDTCQRNGLEVLDLQPFLFYEGLLDRAQHARLIEKMKVWLQLAKRLHTTTIQIPANFLPADQLTGDFDVIAADLRLVADMGAAETPAVRYAYESLCWSTHVDTWDKGWDIVRRVDRPNFGTCLDTFNIAGRVWADPTSPTGKAPNADADLKDSLERLVRDVDLSKVFLVQVVDAERMTTPLVAGHPFHIEGNPPRMNWSRHARAFMYETDRGAYLPAEDVARAIISGLGYKGYVSMELFSRTMSELGQQVPVEHARRGIVAWKKLQERLCLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGP5</accession>
    <name>A0ABR3YGP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HpcH/HpaI aldolase/citrate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000137">
        <property type="protein sequence ID" value="KAL1887195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF9">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="268" mass="28616" checksum="33D4EC38CA7AFE5E" modified="2025-10-08" version="1">MAAIQTTAQTTQIVNPRLRLLNKLRAGEYPLLTFVALPSVRHAQIVALTGVDGIVIDCEHGHIGDDSMHNAVAAIAALGVSPIIRIRGTSHDIIKRALDTGAHGIMVPQINNADEARQVVQSSKFPPYGVRGQGSAFPAIAHGLTTPEYMLSANETIITMIQIETKAGVENVDEIAAVPGVDLVFVGPNDLAQSLLGYVPAKGDEPVFTGAIDKVIAAGRKAGKWVGRMVNNGTTAKQERSKYDMVAITGDTKAIQNWYIAEFEIAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGQ9</accession>
    <name>A0ABR3YGQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000126">
        <property type="protein sequence ID" value="KAL1887343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22386">
        <property type="entry name" value="KH-I_KHDC4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047889">
        <property type="entry name" value="KHDC4_KH-I_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031121">
        <property type="entry name" value="RIK/BLOM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055429">
        <property type="entry name" value="TRAPPC13_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055427">
        <property type="entry name" value="TRAPPC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744">
        <property type="entry name" value="BLOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744:SF0">
        <property type="entry name" value="KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23647">
        <property type="entry name" value="TRAPPC13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06159">
        <property type="entry name" value="TRAPPC13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="203"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="825" mass="88507" checksum="203A89FA99EBA5AC" modified="2025-10-08" version="1">MDSSERRSTKRSRFDQTEPEPKRVSRFDRRSRSPPVRRDDAARDRDHTSREPEASTSGDQETKRHDPAAAAAAIAARISEQLQTRKSSSRDIDESAAAPIATTSVKATASASAANINGEIYISDGDYIKDIEVNDQRNRYINPPLYLHITSTSKEGLQKAIDKVNELLHSELPPLVDERRFRRREREEQPAIERDEYGRKKWPDKQIPVNLEPIPGFNLRAQVVGHGGAYVKHIQQETGCRVQIKGRGSGFIESSTGRESDEPMYLHVTGPDPEMVEKAKELCEDLLENVKDQYESFKSRPQRSYGGQGGYGDRHSNGNHYGNYQGYSGGRGGYGGRGGRGGYNGYGGHGGHGGHDRDGNDHSGYNSPNSAAGNASSTISGHANRSPAPSATPATPAALPSGTPDAAVAAAASAGSADYAAQYAQYYGTNDPYAPYGGYAAYVQYYQKYYAAAQQAQQQQHATPTPPLGVAQSVTSPPPPPPPSDAPPPPPPPPSSDGPPPYPIAAPLSSKVPPPTASASLSFRGPPSDNLSSSTNPDPFLLSPILNLPPSFGSAYVGESFACTLCVNHDVVRETEADAGGGPRKTVRDVRIEAEMKTPSTAGVVKLDLATDENGAAAAGAGGGSGGVDLEAGQTLQNVVRFDLKEEGNHVLAVTVSYYEATETSGRTRTFRKLYQFICKSSLIVRTKAGPYAAAVPSSQLQKTGGSTPPQRWILEAQLENCGEDVLQLDLVMLQLEPSLTYEDCNDWDNEVKTPSSATGFGSRRPVLHPGEVEQVSFLIQETDPGLQEESNGRLVFGVLGIGWRGEMGGRGYLSTGKLGTRVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI40</accession>
    <name>A0ABR3YI40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NineTeen Complex (NTC) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ISY1</name>
        <name evidence="6" type="ORF">Sste5346_009941</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000106">
        <property type="protein sequence ID" value="KAL1887882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="267" mass="29624" checksum="26FB35987EBEEDED" modified="2025-10-08" version="1">MARNAEKAQSMLFRFRESQAADLGITDIGRQRRPKVISEQTNVSNCERWRGQVLKEISRKVSKIQDAALSDFQVRDLNDEINKLMREKHMWEVQIRNLGGPNYTLRTGPGGKSNKEYDENGREIPGAGKGYRYYGRARELPGVKELFEAARAKAGGGRRDDKGGAGGGADAPLEERDDLRKDVDAAYYGYGPDEEDNTLLSYEAAREAEAHARLAAAADAGGKPPPGWEPLPGDIGDGKGGWLLPTVEEVQQELLERRKQRILDQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIA4</accession>
    <name>A0ABR3YIA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228:SF2">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045557545" description="Kelch repeat protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="531"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="566"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="620"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="746"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="886"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="623"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="842"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="898"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="927"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="956"/>
            <end position="966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="966" mass="100616" checksum="C197FA2064A7EE77" modified="2025-10-08" version="1">MKSFTSLLFASSGLVASASAQAAGWVPGQINTTMCYWEQPRAAVVRDTLYIDGGTLWWIPGMNDSSYGGVIGDTNPSGIVYTLNFSVPFKTSDNLTADMGVLYKVSPGSNANNIAPNYFDGAMLANDDEWFLYGGLLRNTNLYSMPDSDSAQMYQIDQYGADKATFRPGFFNVDLPTDVTRYVAYGGAASAPSENKAWYFSGLRSPSWGPIYTVSGVDSMTAINVSNTLITVDMATQNQETWTNVTLPPTVSGRANPELVWVPVGAQGILVAIGGVVDPQWVSISGISENAAASAADSPAFVTTIDVYDVAGKTWYKQPTTGGGNVGQRARACAVVATAADASSFNIYYYGGFDGINVDDSFNDDVWVLSLPSFTWTQVYESDQASTHGRAGHKCAAPYPDQMFVVGGYTPKAGGAAGCLGGGVVQVFNLSSASWLQEYTPTKWSKYSVPDAVVKVIGGNGKGGATATAPAASGGWGATGLKAVFATAYPTSKLTSYYPYPLNANATAAPNNTHPDAPDSSTISGHHTPKFVAPLVGVIGGLIVVAAVAVAFVLYRRRRILMYGSAGTQSGAGGAGGRRSSRGTGPVGGSGMPGTESVATYDTGRNFVFSWLRAQPSVKHASTPATSSYDDPHSSTNGRIQSYGGQFSSSTPISPEMEQLQAANLAAQHPGQGQGYFYSHGQSPLATSGVTAAPSVEADNTYISEMIADTKYRAELPGSSDFTGSAITDANSSSRMVHGGNYYHSVPSSSAELESPLNHGGSNVANHGSNNSYGNLPQQTQQPPVIARADSPSLGQAPQFIAPPLQQQTAQPSVAHSVARESGVSDLSEQDRRHLRQGSEGGQSATSGVSSAVGTSGYQRNSLNLSGAVSPLGSQFPPSVTGIVAGGAQPYPTQPIPEAEAGAEAAAEAAAQPSAPLPMPTPPIHTDLQQNPLQSPSQTSLQGSGGDSPGQLRRSVFRESEADLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIR4</accession>
    <name>A0ABR3YIR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000128">
        <property type="protein sequence ID" value="KAL1887314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="730" mass="80702" checksum="DB2E66692CC6BB04" modified="2025-10-08" version="1">MRKFFACDECKRRKIRCSGGDRCANCDRDAKACRYSSPSQRLVALQRRLQESEHVRRRMEQAWAVYLPGVNLADGLRNLPKHKAAHDADETDFTDYVPQPHRHANSNHDHDKDRRSTTTITTVTAVDNDTTEPQTPLPPTEHLDADDLDFDESEDPERAIDGMAFLTAGPHKSGYTGPQSGIAALKFMQSLPPYLPVTYNPENTSPSNTSPLIDDDVPDVATHTAAARARYIDDYFELYHPAYPILHEGTFRARVAGALAKPRDGSWPLLYYAVLAIGAFVSGGGAAAAGADPNTHNTGKDDDLSFFREARRHLGMAVLEKGSLGYVQALTLLANYLQKRNKPNTGFILIGTAFSMAVAIGLHREFGMPRTSPFTMELRRRTWWTLYVFLSGAQLALGRPAVSYSEFEVSVRLPANLDDAELAVDMDQLPPEQVGRPTVASCLIEQVRLARLANAAHAELAVHRRPPAATVARLEERIRVWRSNCPAFFLEDEHSVLEPRLEYPKRVLVWRGLNLRIVLNRPFLFEAIASGAQLPLVNGNENPVYSCLMAADECAASICAFLRSCHVVYRGFAWYTTAWLMTASFVQATCLIYMPGHILATGWRSSLQEAVECFRRLGASVDIALRARDILQNVLNHASDTAMQPLSTSTSIDTSAPTDAHTLARLSFEGGFQSGFQGGFHTGFQDNFSWLAQSHAQSERHGQGHDHADGEFLGPSAVGGFVYGNGFDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY2</accession>
    <name>A0ABR3YIY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF289">
        <property type="entry name" value="GLYCINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="374" mass="40303" checksum="247BFB905360C3F5" modified="2025-10-08" version="1">MTVDKPHVIVVGAGIVGASIAWHLAAKHGHNVKVTIVAPDVGGTATPNSFAWLNANFNNARPYFDVRHRSMARWHELIKEVPGLLELARWNGNVQWQQDEEQLDFCIKQHASWGYKAEKISNEEVLKREPWLADTCLPSSGWVASLPEEGSIEPALAAKKMIEHAATAFGATLRQETVDRLLVRDDKVVGVVTSSGNITADHVVLAAGLGTVKLAATLGIDVPVNSRPGLIVHSKPVSTRLLNGLAISNGPHMRQTVQGRIIAGRHYSGGNPTTDPAAEADIFFKKVQAMFRSNLDSTPLPSLELDFYTVGIRPDPKDGLPILGDCGKKGLALAVMHSGVTLAAFVGQTLAELVATGTKDKALDQFSLSRFNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJQ5</accession>
    <name>A0ABR3YJQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U4/U6.U5 snRNP associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SNU23</name>
        <name evidence="7" type="ORF">Sste5346_009491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040107">
        <property type="entry name" value="Snu23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986:SF1">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="6">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="160"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="234" mass="26302" checksum="57B6224B7FBF0DF4" modified="2025-10-08" version="1">MSKQGSAYGTPAGDTEFRKTRDVAEYAVKAKEREAKEREEAKARYEAKLTGKKYYKPLEGNETLTAARTTMADLNALVGTTQMVAPGRRAGPLYCKYCDWTAKDSVALTEHENSMYHLRNVGQTGQVKRASAEDVLARIEAVWARLEAEKKDATINLKERLAIRQQEDDAERERKRIKKRDLAEKKKAAKEAEAAALAASRMDYGEDVRIEGEHDEEDMMKMMGITGFGSTKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKG8</accession>
    <name>A0ABR3YKG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_009567</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF38">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="11"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="48558" checksum="170446E860671C14" modified="2025-10-08" version="1">MAATTTYNLTIVLFVALSALTYGYAFSVFSTSIGQPAFYAYFKLDQEGPGAAHTASILGILNSLFSAGAAFGAISMAWLPDWIGRKCTIVIAAGISLVGGALVTGSVNIPMMIVMRFIHGVGVGQCITITPIYLSEVAPPNRRGFLTGQNAVALVFGYLLSAWVGYGTYFSNNGTFAWRFPLALSCLFPLILLAGSPWIPESPRWLIWRDRVDEAWKITAKLHHDTTDPTQRMAKAEFFQMRTQIDFDRTQDLSMMHMFKKPSLRRRILLGCGVLLGSQACGALVINNYSVVLYEGLGMKDSMPLLMYALYIVVGMIFNIVSSLIIDRVGRRTLFLLGWTGTAIALSCETALVARYAGTENHGGNAAAVLFLFLFVTIYGSCIDGTAYVYCAEVFPTMYRAKGMALGLFTYYSASLAFLTPAATALNNIGYGERLNVMLMLVWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLC2</accession>
    <name>A0ABR3YLC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1888993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF284">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="54576" checksum="87361FCF0F42610D" modified="2025-10-08" version="1">MDQHAAVPVTLPRARPTTPFWQDPPDADVADLRSTPELPVSVDVVIVGSGITGASIAHHLQKSGSSSLLMVEARQTSSGATGRNGGHTKAASYRSFQDHVSALGVEAAVQIARLELAAIRGVHRLAAGGENVDDSKGIACDSNPCDTLDVVYDPAQWTAAQEAVAAMKVVMPAGDPAAEYTLYTREESLSLFPCSDDVDETTGEVTAICGVVRYPAGSVSAYKFTVGILKRCLAKGLNLQTNTPVLSIDKNDSGRWEVTTDRGTVSARHVVLATNGYTAHLVPSLQGVAVPLRGQITMHRPGSRMPDVAGEGTGLQTTYSFIYNGGYEYMISRPPGSTCAGDIVIGGGLKFADTTEEGGAGTGGLCEYGTTDDTTINDTVSAYLRGAPVRYFGRGSTASGGGHSWGDDHPDGRIRKEWTGIMGYTPDGYPLVGEMPSPIDGEDNSGLWLCCAFQGHGMAYSWPCGQALARMILAKELDDTAKQQEQDAALRKWFPDCFRVSEARLKLRFAGRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLG0</accession>
    <name>A0ABR3YLG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flap structure-specific endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009053</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09906">
        <property type="entry name" value="H3TH_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09870">
        <property type="entry name" value="PIN_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041177">
        <property type="entry name" value="GEN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037316">
        <property type="entry name" value="Yen1_H3TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18380">
        <property type="entry name" value="GEN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="109"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="522"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="573"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="69675" checksum="846E91A1FFC9B29A" modified="2025-10-08" version="1">MGIKGIYKEIGAGARVAFLRLAVDSLEKRGRPLRLAIDISIWQFQVQVARGGSNPAIRTLFYRLVRLLGMPVQPVFVFDGLNKPLFKRNKRSSGPGDMVASSMAKRMIRMFGFYVHEAPGEAEAECALLQQHGVVDAVLSEDVDTLMFGCTRTLRNWSAATSTSTGKGSSTAAVTHVTMYETDAAAATSIAPESILKTHETGLDREGMVLVALMSGGDYLPEGVPGCGVKLACEAAKAGYGRTLCRIKRSDTAALVQWRSNLQHELRTNESKFFRTCHHKLVIPEDFPNLDILRYYTHPVVSPADVVERLRAELDSAVDSAPKAAMLQATEDIKPKPVDILALRDFVAETFDWTNRGGAIKFVRVIAAGLLTRMLFLKWSSDSGKDDVDEDLDNETGIMDRDLLPSLVEGISRQRTHASTDNTPELRVSFIPVNVVGLDLERELDDPETTFGRDGLALNSDDEFDEPPATLAPTVPGYTAGTLTVASSRKLTTGTPYDPTVSGVAWVPRTVVQIGAPAALGEWEKKQQRSKKGTADGTKTTTTRKPKDTTKAVKSKMPAGSLDRFVRVTKNTGGGALSASSQAAPAEKPASRLTATFKSRPDLLQRLDSDDDASFGTDSTQRDGTSSIAEVKVERKAKVVVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLH2</accession>
    <name>A0ABR3YLH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7892 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057214">
        <property type="entry name" value="DUF7892"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25422">
        <property type="entry name" value="DUF7892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7892" evidence="2">
        <location>
            <begin position="671"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="817"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="888"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1096"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1177" mass="129372" checksum="66DB1A7FD56E235D" modified="2025-10-08" version="1">MDTTDASKSNGSTDAPDVVMGDNASHQENDQEVDPLTKKRKATDGDASASASASADTNAVSDATVELPVQSKKAKLDPVPNVPADRSLLPAEEMDLLMSTAPTFLIPALPFVFVTSLSSVVPLHAIQRGQLPPSCTLTKIFWTSDVDTLREEFDSVKELGAPAVEEWQKGLSKRGSDQKADSSKWEKYDESGGVTNMRTLLHPEIKPQAAAVLEPPKISVPPKAAETPKTAIPADKPTVEPKEPASSEKSDLGAVVKPPPPPPPPPAKPKTAEEIDADWDFIQGPVRLKILRYAEEAIAGDWDDGDKVTKDNAPAFAADVLLHVRKRFYMEVDKEAQAARAAGRQPVVDPAEGPFTQKLTLENMKYVFDVKIKPITSKVRTELFACPLCDVSAKFFGFEGTIQHYAAKHTNVLSVGNIVVFWRAEWPEQPPFRPNPRVHKGTGTPVPLHPPSAVSVPNQRGPGPAAKRSGKDYQSFGPPPPGHFPAHQQPATYFPPPPPPPVQAPVSLPPPPPPLPLQQQPYQLVRPQILPFSTSNNGRDEPQYNGPSFAHGAQQAHTFGAPSYNHTGQPQTGPAVFQTPPFHPQPQHAAYQPFAGNNGRGGDRYAGAPSAAPQVPPRTAPPAAPVPSAPVPAQIANPFAASAPYQSQAPALAQPPAENKANNDPCAPKAPYQDRLDAVVRYAHEVWEGIMCLVNTTNEARAYALIYQTNKHFWGKFGEELPLALFKDRILNYKGMQLMGTARDFHCQACRLGLDDVPDNKKGDTSFRFRELVVHFLKEHVDGRTMKANPFNVNARKPERPIRDWLTQMAPAVAAAPQNARKVVPDTNDNQKLQGANVNKDAGGRATQPGVKIKEEEGTNDQPIASVRKAAAPREEPDLLGALEMHLDGEPVRRPSAVTRDPAPEARAPTRVVYVDEYGREVVPRYDNQRELHRDPRGCPRDADPYGYVVDERDESYQRRLPSPRGYPGGYGPPSRGPSGQYRERSPLPARRYVDERVYSGHLRNYEDEYERGAPPGPPRHYARAPPRQDFYSGYADGADRGGRPYRPVDYEPYEAYEVVRVAGPDGEYLTRRLVRREAPPADRRAQEHYYLREYVDDHRGPGPGYGARYDPLHAAAPEHEQRDVGEERSALPPQQQQRSVVRSDPSYYQEYDPHNPMSGGPMQGQEGSGLGHMQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLT8</accession>
    <name>A0ABR3YLT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF141">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163220" description="PEBP-like protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="18609" checksum="7FB989D567FA02F4" modified="2025-10-08" version="1">MKTSILTLVATAAGLVAAQTPDGFTPSVATHLDVSFGSKAVSPAGTSLAKEDTTKQPTISFAGANATETYLFVMIDLDVPSGTSRNTLLHAMIQDFKVSGSGPTLTSTATGPASYMGPAPPKENPAHPHHYVEVLFVQPAGFAVPAAQASVVKSRMGFKLADFAVAAQLGAPVAGNYFTVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLU8</accession>
    <name>A0ABR3YLU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20916">
        <property type="entry name" value="CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20916:SF18">
        <property type="entry name" value="IPT_TIG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="675"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="549"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="718"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="748"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="759"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="807"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="837"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="868"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="896" mass="94978" checksum="7E7DBB6C6893FCC6" modified="2025-10-08" version="1">MSDRVPEQDSFRNEPQCYNCGITGHQTIACPEPTRAVPAGLEAHRKRQASKDNNFNNHHNNNNGGGRRSFSNHNGPASSQSRHANGMVVTRYPPPPGSGGPQITHYPQPPQQQPPPPPMTQAPPPPPPTLPPPPPPPSSGNGGTPSYHHQSQQHHPHHSPYGGHHPQGHESWQYPQQQSPYNGGQYTPGGGPPSAPASAPPNFPSYDSYNNNNNNNSNNNNNHHHQHGPPSGPGSAGGPPPPNAPYYNQHYGPPQSDYFPNPPPGVIGPPVGPPPPPQYGGGHSYPSSLPPHPPQPQHAYPGTPGAYQPPGYMSHPGGDQGQYPPSASSAPPAAPMFNGGNGNNNSPWRNNGNNNNNSNKRGGGNVGNYNNQHNNNRGNHRGGGFVRGRGGRFPSGQLHSPGGTQHAGSPPTGPAIPTGPSVGTPNSNGANWADKSPPKLETNNKPATPATTTPMMHKLPERPPGMPPKPPTPISMKGGGRPGAAMGHNHKPRDDTNSHHHGQESPSVHPGGDHHDTSNLHQKRGRDDYFGKDEDRGDNKRTRPSPAFGSPHGHPGPTTPRGPSASLNSGGAATSPHAPAASSTESPNPTRTGDRFINNIPTGPRNGPKGHNNNNMPPSGPNGHGGLASKLPGGLPSSLPANPVWANRASRILSYGQQKPGVTVVNELVVPSTKIHSPANGTAGINIPTGPRLLSAGPVPSSLPSRPPPSVLKGADGRSTSRSLSQTGDALSHTYSRSRSRSRTVQATDDHSRGDRSCTRTHTRSRSRTPRSRSRSRSGSRTRSKSRSRSSSPLDDLELAMLGMAQSAGDRSSGRNGSRSNGRRARRGSADTDGSRSRSRSRSQTRSRSRSRSRSRSHNGEDSDASSSRKKRMRNVNGRIPKRRRPKESSVYSRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM55</accession>
    <name>A0ABR3YM55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-repressible protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020100">
        <property type="entry name" value="Glc-repressible_Grg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38789:SF1">
        <property type="entry name" value="GLUCOSE-REPRESSIBLE GENE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38789">
        <property type="entry name" value="REPRESSIBLE PROTEIN GRG1, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11034">
        <property type="entry name" value="Grg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7379" checksum="740C6CF5DF7F4DE0" modified="2025-10-08" version="1">MDTIKQAGNYVSDKINAATSDASHEANKSVAKDSNASIGDRLQGAGNAVKDKADQKGYDASAEANKQKATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN81</accession>
    <name>A0ABR3YN81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat-containing domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="35720" checksum="5E1E05181DDC2DCF" modified="2025-10-08" version="1">MNETELEAAQKAREADVARYAAYQADPVAARASEIAARDEKDRRNGPGQGPDTYLTPLAAAALFRNALGVQALLQIPDTDFSTDLMAPSIPASFRTFRSGENGETASIPAGTTAMRPLHAAMIGPVYKQLHAATYAVTDTATAHKGYLDDCLTTVQLLTTNTAVYAATINATHPYVSPQTGKRYHYTPLHLGARFDRLPMLRVLLNRGANPSIPVPHTGRSVFFSVFASLLRLCSYTGRLVETNYGGTFNGPLYRDRVRDIDASIGTAALVNEADADGNTALHWAMGFGLSYAGAALLALGARPGARNNAGEIPTDGTPPTTKMRVKGYREFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNG9</accession>
    <name>A0ABR3YNG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045791635" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="39267" checksum="3AFB08A2BBD429EC" modified="2025-10-08" version="1">MRVISVLALGLLGPGSVLASVCKPSPASSASPSLSSLSSPVSSSASSSSPVSSSASSSISILSSVPSSSSISSVSPVSSSASSSAAAQPTCGVNILSNGNFVSTYDWTFVDVTGAGSFTTETNGPAGYSTYLQYATTAAGTSYMYTTFITVPGTTYSLDYAYECTSDIGITGIHAQLSQGAIWVQSVTATNVWTSGLSGTFTATATTTTLTFTFSCNEYLTVGFTNIGVSAVCEAAPQDTGGSGSTRPQLATIGGTGANSSGFRSRNRGTNNDNDGLDYVELKSFGGSAGSNSHIGDSSSNSFNSSSDGAAYHTSRSPATTRQADPGNSSQEGLVDELRRANGGVVNVTVSSGRPNVAGNGSGSNTPGGIVVTNTHVLQRVEGNDYAGYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPD0</accession>
    <name>A0ABR3YPD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">FAD1</name>
        <name evidence="15" type="ORF">Sste5346_009003</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23948">
        <property type="entry name" value="FAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="14">
        <location>
            <begin position="207"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="291"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="37269" checksum="2DAB43593F5D597E" modified="2025-10-08" version="1">MTSDQHTGRSSALAGDIAPTNGTTVPYTNGDDALQSQAQSLSQPAAAGPHHFPDVCYKLRNKVLAFLDEEIPASEELLKNMQSQVRISVDVVEQALRRYTLEEISLSYNGGKDCLVLLILILACLPICNEAPKATADAPVPAPEANQAQATQPPAATASAAAPTSTTPYPLQSIYIVPPDPFPEVDEFVDESTAEYHLDLARYPLPMRAALDAYLADRPTVRAIFMGTRRTDPHGEFLTHFTPTDPGWPQFMRIHPVIDWHYAEIWAFIRHFDIPFCQLYNRGFTSLGGTTDTRPNPVLAKKAKGANADADNDSGSSTPTSFRPAYELMDDDEERLGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPV6</accession>
    <name>A0ABR3YPV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="88" mass="8134" checksum="302D7C3B4A578D9C" modified="2025-10-08" version="1">MFGHDGPREHHNGQPGPGGPGHNGPRHEGPGGPNGPRNDGPGGPGGPGGPGFGGPGPQGHGGSGPQHGHGGPGGPGHQGGPHGGPHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ65</accession>
    <name>A0ABR3YQ65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="277" mass="31264" checksum="324B560B25F42466" modified="2025-10-08" version="1">MRHIQAAPEILNIHLGRTGCDQKTRRKFKTNDTLEVPGFLDVSRYLEQHVFAPGSQVVYRLASVVSQRGDTAQSGHYVSYVRDGGATPSRAAEPIMEAEEVNCVMQESLDLKEHVARECRILSETIMNEDATLAADGQSHLLNEVRREANSQRFLTIERVKATTLGIPFTRIINTSLDPTYHPDNADWFDPVLLVYEKWIEKYHTDEETGKRIYQLPVNVPNRDYQGPARRGKDGTVQCHDDNNGDAVGVGAAERRYQENIKHDVHIPFPGYATPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ81</accession>
    <name>A0ABR3YQ81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PNS1</name>
        <name evidence="10" type="ORF">Sste5346_008428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="61382" checksum="16A219B6B0FDE67D" modified="2025-10-08" version="1">MSGEASSYYNAAGGGGQNGNGGYYNQDLEAGNRNNYNGAYPEANVNDQAPPPGYNEPAAHKGSVHEVPPNGQNGQGGQPGHPQQRMQMDGKQEYEQMFQVKKDNRYKDWWAGALFIAVFAGFTAVSGISLHGYATTRSSTGGGIYGSDSTFGLTTNTIICLIICIAVAVILSVLYMMVARTWTKMLIWVTGILNICMGLATAIYMLYQKYWSGGIVFLVFVVFTIICFISWIPRIPFSVVMLQGSMDVARRHGHVFTVSLIGGILAAAFGVWFSITMVAVYVKYEPGNNEACNASGGGCSQAKVIGLMVFITFAAYWITEWLKNTIHTTIAGIYGSWYFSRDDAHFPRGATRSSARRALTYSFGSISLGSLIVAIINFLRQLCSVAQQQAAGSGDTLASIFFCILGCFISILDWAVQFVNRYAFCHIALYGSSYFTAAKDTWTMIKNRGIDALVNQCLIGPVFSMGATFVAYATALSAYVFLRITDPAYNANGDYTPVILAYAFLVGLQVCNIFTTPISSGVDTIFVAMGWDPRVLMENHHELYQRMVDVYPRVQQAIQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQH9</accession>
    <name>A0ABR3YQH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NAG2</name>
        <name evidence="10" type="ORF">Sste5346_008224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate</text>
            <dbReference type="Rhea" id="RHEA:22936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="3.5.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="81"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="494" mass="52826" checksum="4A6593A72C91B0AB" modified="2025-10-08" version="1">MPSLITTSIPASPITTTPSSPTAPGTRGITKLTNCRLVRGNDLVWEDLWISSNTGKIVRSQAAFYDHHVLPDETVDLGGRIVAPGMIECQLNGAFGFNFSTLFGDEDNAAKGQPTTYETRLRELNRKLVQTGVTSYVPTVTSQTSELYHKVLPHLAPHRGEAKDGAESLGAHVEGPFLSPTKNGVHNPEVFREATAFADVEAMYGAKNLAGDVHSTGTDENSRKPAVRMITAAPEIGRMTDVVFPELRRRGIVCAIGHSEATYEQAAAAISHGATMITHLFNAMRPLHHRNPGIFGVLGETPLVRVDNPSSSLEGAVAPSPRPYFGVIADGNHLHPTTVKIAYNAYPAGFILVTDAMHMVGCPDGPYDWTNGGHHMRLVKDGKVLLLEGTDTIAGSTITLIECVENFINWTGATIPQALRTVTSTPAAMLGLQGVKGSLDAGADADLLVLSAEEVLELPSSPTTAAVTGGASVVTTRLHVDEVWKFGQRVHQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV1</accession>
    <name>A0ABR3YQV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008049</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045796474" description="Serine peptidase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="61203" checksum="FA05DDDE5FF46A2F" modified="2025-10-08" version="1">MHPASRWPSLFLSLLLVFTHSADAFFHRPLRPTLPPPPRQLLLFGQTPVKHVCDGSEPNTGVAYFDQLLDHSVKQSKCKLSLPRRTFKQRYFWSNESWGGPGYPVIVMSSGEGSLDGFCSFLHPPSLLAKIAERVRAAILVIEHRYYGESSPFQRLTTQTLQQLTLYNAIHDLTYFARNVKLPFDPTANTSKLSNAPNSPWILSGGSYPGALSAWTASLDPGTFWGYHASSAPVQAVYDFWQYFEPIRAGMPPNCSRGLADITAYIDHATMTLPPTELAALKDEWGLGVVTDPADFASVASFFKDKILPGLCYERYGYKEFAPNNNTDSPIATCLNSFNSSSIIYTDRAVNNSMNVQWSWMLCNEPFGWWQTGQTPPGLPAISSRLMTPEYFQRQCDVMFGPNSAEFKANGGGPFAGGDGIASASINSATSNTYGSATGKTAEMLNDWTSGWEFNTRRILWVNGEFDPWRPASVSSTFRPGGPLESTPDAPVIIIKGGRHCEDFFARSNNTYLANVVEQEVSYIAGFVDEFYDANTKPGQNRTLSRLLPMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRY9</accession>
    <name>A0ABR3YRY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Isopropylmalate dehydrogenase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007901</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050501">
        <property type="entry name" value="ICDH/IPMDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275:SF1">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="233" mass="25610" checksum="5E22DCD6341257F1" modified="2025-10-08" version="1">MEELFQTFTLDIDILYWSSNKFLETGNENHVGGTTHDDTPYTIANEVAVFTRVGIERTMRFAFDVTRSRTRKKLTMDKVFYELAREYPDIEIDKMLVDVMTVRMILKPKTLDTIVATNLHGDILSDLAAALAGSIGVMASSSLDPTRKNPSLFEPIHGSAPDIAGQGVANPVGTFWSAAEMLRWLGEDAAADLLMKAIETVTASGLEAKDLGDTCNLKQVTNAVISELKNSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU31</accession>
    <name>A0ABR3YU31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">V-type proton ATPase subunit F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA7</name>
        <name evidence="10" type="ORF">Sste5346_007660</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Vacuole membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="entry name" value="ATPase, V1 complex, subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005772">
        <property type="entry name" value="ATPase_V1-cplx_fsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01101">
        <property type="entry name" value="V_ATP_synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861:SF2">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015945">
        <property type="entry name" value="ATPase_V1_F_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="AtpF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="13863" checksum="E5F4D09FA25160D1" modified="2025-10-08" version="1">MTTTAADFKDRQFLAVIGDEDSVTGLLLAGIGHVTPGPDAQKNFLVVDNKTDNSAIEAAFDKFTTERKDIGIVLINQHIADRIRYRVDTYTAAFPTVLEIPSKDHPYDPEKDSVLRRVRRLFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUF6</accession>
    <name>A0ABR3YUF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein component of the small (40S) ribosomal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS19A</name>
        <name evidence="5" type="ORF">Sste5346_007305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_eS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="152" mass="16805" checksum="D2B298F67697E8A9" modified="2025-10-08" version="1">MGGVSVRDVDAQKFIVAYAAFLKRQGKLPIPGWVDTVKTGHAKELPPQDIDWFYVRAASVARHVYLRKTVGVGRLRKVHGTAKNRGCRPGKHVNASGSVDRKVLQSLAAIGIVEVDEEKGGRRITQAGQRDLDRIAQTTAEEEEEDEDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX4</accession>
    <name>A0ABR3YUX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="7">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="7">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">MDE1</name>
        <name evidence="9" type="ORF">Sste5346_007546</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="8">
        <location>
            <begin position="23"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="272" mass="30935" checksum="89173F648EC61F28" modified="2025-10-08" version="1">MSGEAANNNEQLVISDDPKHPANLVPSLCAKFWTLGWVTGTGGGASIRDGPSHSDLVYIAPSGVQKELMKNTDIYVMSLEAQAKLENEQKETGKYNAYRPDRTYLRSPASLKPSQCTPLFLAAFTKRRAGCCIHTHSQWAVLVTILLEHDQRHARNRREFCINNVEQIKGFRRGFRRTGNLGYHDTLRIPVIENTPQEEDLTPFLEEALEEYPDTYAVLVRRHGVYVWGDTPDKAKVYAECYDYLFQLAVEMHKLGLPWISDVKPVDLKRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVC7</accession>
    <name>A0ABR3YVC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoplasmic reticulum junction formation protein lunapark</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in determining ER morphology.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lunapark family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040115">
        <property type="entry name" value="Lnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019273">
        <property type="entry name" value="Lunapark_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166:SF12">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10058">
        <property type="entry name" value="Zn_ribbon_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Lunapark zinc ribbon" evidence="3">
        <location>
            <begin position="282"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="43871" checksum="6DEEFE9AD735552F" modified="2025-10-08" version="1">MVSLWPWKRSDDSPASFEKVLSALATKIANTQAKLDRTRATSRRARVLCTLYLTFGYLVYAIVLVLVVGWKNMGPWEWSGIAGGPVLIYATRKALAAVYNFRIDSLASKLKEQQGERAKTIQKLKDATKYDSTLQLLEKYGGAEPKAGKGKGAGGDNSGQEGKRGSKGGAAGGPGGNPSTPNRTRLPPPPTANIQHGGNINIQTPSSKQGTPRSAADDTSIVSAPGSPAGGVTDLSASAEFAPNAFGPDEVAAVPQVTGGQYAVSAPSAGGGAAAVYGESHWYDRILDALMGDDETAAKNRFVLICSSCRLVNGQAPPGTKSLAELGSWRCMGCGALNGEAAEAKKIVREMLQRNSSNSNKVTEVADSEAESDNGDSIEAEVDPETIEVKEEEDNQVATGKDSTNTRNLRKRGKKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVH8</accession>
    <name>A0ABR3YVH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="526" mass="57988" checksum="FB6C269914BC8A1D" modified="2025-10-08" version="1">MDNNQSLVGYDPSQVAQYGVAMQSQQQQQQQQQQPTPQHLHHHHRHHSLVGWTAHPVAAYQLVPMDGSGGCGGYQPMYAHQNQSQPQQYQQIPHQQMSQQQQPTLYAFPQNMAMQQMQNMPPMTPMSPITPMTPGSGLSPIRRQPSFGNGSFYHPSPTQYQQFPPPGHQQQQQFYQLQPQGHNQHNHQLQRSQSIPVMSSHVLSGSPEVTGAFGLSPLRRAHEPYSPSMVFATPQPQPLPQPATPARNQTQDNSGDVFMDSPAVQAPFPLMPTLHASFMNHRPNKPKPLALSQSNLHSHRVGDENDPDHFQSAAQLAAHRRKPVSSASTGALPFPPSVTPVGSDREYDAGGSSYSTSPLGSEAQARIRARMRIPFVPRNLRRTATSVRVGTTVNESMENTPTATAATVLSVQPESSLEQFLQDHIHSIEANYADEKDDIEANRKGSGGGADRLLSSSDEWYTTSGTDPIRSRHRHRVVETHPRDKDGASSSASGVGICDCGMQQCCQCGLFISRPETHMCMVKKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN1</accession>
    <name>A0ABR3YVN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Component of SWI/SNF global activator complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SWI1</name>
        <name evidence="6" type="ORF">Sste5346_007134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16871">
        <property type="entry name" value="ARID_Swi1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051232">
        <property type="entry name" value="ARID/SWI1_ChromRemod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964:SF27">
        <property type="entry name" value="HAT-TRICK, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964">
        <property type="entry name" value="RBP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="5">
        <location>
            <begin position="442"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="388"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="546"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="603"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="636"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="671"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="702"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="720"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1243" mass="135328" checksum="C9AB3DDFA66CD817" modified="2025-10-08" version="1">MSSWMNEAAVQNHNGNGFPHINNPNAPPVGVGNGMMDPAAFMAANQAQFNPVAGNPYASPQQLMMQQQQQVQQQAQQQGGARNASPSAFQNPMYQTNSVIPSKRPRPREDSMAASPRQNSGMLPTTRAETPGQQGQPGQPGGPQSTPQPPSFPHNLPPNGSANATPSPIMANQIRAGSAVPQRVATTSPHPFSPATQSFVPQASPAPSDPNTAPNQQQQQSPYGQPGGGNFPPGFNPNFTPTPPPGQQRPSPNPQQAGGQMMPQHMGQMPPQMGGMGQMNPQQMGQMGGPGGAMGQMNPMAAQMGQVPNANMFTPQMQQQLAQARNPLEQQKLMYQMQLQRQLQQGQMQGGGPQMPGQSITAQQRNMIARQQQQQQQAQQQAQQAQQQQQQQQQQHQQQPGQQPPQQQQQQPGGPNGQIAPNTPKTAQGPGGAPGQQPNGPQRSSDQFMNQLSMFMQRINMPLETNPVAGDRPMHLMQLFQTVQKFSGYRNVMQNNVWPQVSNALGFPPAQIPTVAGQIKAIYERNLLKFEDFVVNQSRAKANMQQQQQLQAQAQAQAQHQAQMKAQQGFPQQPGQQPPQPGQQPPGPPGPPGPPQQQQQQPPQQPPQAIQPPTPQQQQPPTPSLDQGGPVGMPSTPKSASRPNKRSASGQQPAALKHAASNGQMNGFSTPHPPGQQPAPPTTSRKGKGKNARSASSSHEAFPPPSPAQPGMPGMPGPPFMDGHGHPANGFVPMPGQFPPGQMPPGHMQGGFMPGHMQGPPFGDTDEYKPCSRDTHTYGGVDVNAPTNVVTDILRFRPEVPAPNELGNIDVHALTMSIQSGIHGEVRLALDTLATVTVTNMPGLEIDLDKCDDLLETLIEYADELLEVLAENTVEVSDEILIPPYEDIARACQIERLSIRDEPELGSEEGELDRAVEYLLCITTIFRNLSFNPRNQAGLADESAVKFLCQFIRYVGTRNMLLRTQLNMLDFMKDIITLLSNISGSIEIPDQQEAFCFLQFLLAFAPSPLPSLADEYIFFPTYHATLQPYLPSAVDALAKLLARDEPNRTHFRNVFAADPSGAMPFDLLTQTFALAISPIPDYIHLREMRPPRLPPVQEVRKPMLMQGLLAADIVASLAPGFETGVTRTWLTAQNGFVQNLHRTVRDLCRDYEMVEHQLRHFRGRDTRGLQKDAEIMYIVVLAVSMLRKLSEKAIDPADPKTSLPPSVLPSEQGLLEALEMLSGEWSRDGFLHNFVAFASLGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN5</accession>
    <name>A0ABR3YVN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_007286</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF228">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="7"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="361" mass="39590" checksum="6FFABF3D13286027" modified="2025-10-08" version="1">MDRPPPLVNAVYYPSWRVYKDIPPSSLRLDKISTIFYAFAIPQEGGDLGFLDEYADAQIDVDAEHGCLDALARVKRDNPHLRTLLSIGGGAGSGAFSGIAATEEGRAAFAKAASEWVHRYSFDGIDIDWEHPQTLEEGRNFLSLLQACRAVLPTPRYLLATALPVDPSVLGRLDLCGVASLVNHVNLMCYDFTGPWSDCAGHHTQLFSPGPHLPSAQTGVQYLLDRGVPPQRILLGIPAYARVFLGARHEGDGFRKDEAEEDDEEKEETEIDYRDIPSEWKQQGMLQVDTGRAAAWAVVPRKKGKRGTKFVSMDVPATVQAKAHFVRRTGLGGLFYWTGAGDCNEDGESLVAAGFDALHSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVR5</accession>
    <name>A0ABR3YVR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049803" evidence="2">
        <location>
            <begin position="19"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="547" mass="52262" checksum="F967C277C60B523A" modified="2025-10-08" version="1">MASLKALSLLALAVGSIASPLAVVPRDDIDDTTTTDTAVVTVTATATVTATATAVVTPPSVPSVDVVTVTSTIVRTRWTATAVVEATLNCTAYVYASAAATAPAAPPVVVTTSKAPAPPAPPVLPSAGGSKRQVAADPSTPPAVAPTPVAPTAPAVRTRTRTVYAVSTLTEATPYLRTRYGCSTTLAYAFTVDTTTTVAIPTTVYASTATATAQITCPGVGGFPYNAGGGGAGGFGGGFGGGFGGGFGGGGFGGGGFGGGGFGEGAGGAGGLAGGRGGAPGAGGAAPVPAPAPTAAPAPAPAAPHQDAISLVEAAQTLPAPQTVLVPADNSSSVAAPAPTPAPAAPTTITTTVHLTNTAYSAEVVNKTDALTVTAYACSQLPFDVTATRAVTVTKWASTTTVTSIVSCAQRAVPAGPPGARPTASTIAGPAGALHERQTDAGPAPAPTSATATVTATATATAAPAPPVVTPTTYHRTTTIVSTATIIPTGASTHVVYNCAPVSVTTVVPVAPTPAPAPAPAPTPAPAPAPAPAPAPAPAPAPAPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW13</accession>
    <name>A0ABR3YW13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PAK5</name>
        <name evidence="13" type="ORF">Sste5346_007302</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="48"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="392"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="446"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="510"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="663"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="751" mass="81184" checksum="40D52B5287A12F10" modified="2025-10-08" version="1">MDRRRSLAVPAVPAVPSQIRAKAIDEARRTQAAVLRDCTATNCEPPPYVLTELIGKGSFGRVFKATSTKTDSVVAVKIISIEEGDAAATDNGAVSTINAPTQTADKTARQPPTSVVDTFGDVLKEIRTLQLLGASGARNINTVLDSLLVGPTVWMVTEYCGGGSVATLMRPTGHLPEKWIVPILREVAEALCWVHGQGIIHRDIKCANVLVADLPETDVAIGGKAPPRVQLCDFGIAGFVETAVDKRRTVTGTLHWMAPELFRVDVEYGTEVDIWAFGSMAYEVATGLPPNATRTLAGAGGGFDMSSFGSYLEQNCPRLVGNQYSDGLKELVAACMVHDPTQRPSTEQVQRFRYIAGTTNSHPTSSLSTLLSAYRLWQARGGGRVSLFSAGGARGVGDTDNDLTASIPDWDFDDSDVDEDDDDSGDSFSLDYEANTLAVYEAYGISLDRSPPLPPTPKPLPRLPLESPPSLPPQSRLRRRPVNQDRALPEVPLQGAFNPNTLTSYHDKAKAAYGRHPPPPLVLDPKPSSSTTSQVSDLPLRGYSNEPDRESLIDLDLSMAMDVVSSKIDVDTVNQDTVRPIRGAGAVKSSLSAMRHRTQDWTFPVASKSPKRDQIQLVDSERGPVLRASIDQNSQKNRVSVVSLIDLDAVTGGRSDGGNKEDTNDDDAPFEFDTPETQNILHRKTLDGTDVLPRTLPPVPMIPTSRVLQGVAERDEARSELLRMLSSLGEHLHLATRTLESLPVHTAMAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW44</accession>
    <name>A0ABR3YW44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="294" mass="30351" checksum="F9D2C7D974DCFD90" modified="2025-10-08" version="1">MSTPVFFVTGASSGFGKAIVLDALSRGYHVVASARDASKLADLKTAGAAVVDLDVSAGDEVVAAAINKAVELYGSLTHVVNAAGYVLEGAVEEATQQEVAAQFATNVFGATATARAAAPHLRAATQAGRQAGLASFGSLASYIASPSAALYAATKGAVSLLMEGIAAELAPWDIDVTAIEPGYFRTELLNSGPGAGTSRMLTPKTRLSVYDNTPASAIRDMLVVTNDSQIGDVTKGARVIVDILTRTGVANGRKAPTHLVLGADCVDTARKTWADREVSLKEWEAVSRSTDHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXD1</accession>
    <name>A0ABR3YXD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_006813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="10">
        <location>
            <begin position="380"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="627" mass="69574" checksum="EE9B6684268FB5E1" modified="2025-10-08" version="1">MDAVTLADYQRGVLRNSFRSAVALGEARPLMLVACAVPAIIVPAVFLAVAGGHKALQPLRYAMAVALVVYNAHQVSPLWNDRSWVRTSSINFASAYGAGLVYGWSTLWSLVVLVWINPWDGERVARRRKTVQDKEKGTPTKGAETDADPQDMQKVEDAPDEDIAHSLRLGHEYYWQSFPARGSFFARFDWALDLCLAWRGIGWSWGKAVVPIFAPPTKPHTRELVRLKTMPERTKQGYRRQLTRAAFYRARLTTLVSSYLVLDVCAVIMTQDPYFVVGPGPSRYTPWSEQADKLPSPDIGAFQTRPPSPALLAMPAYLEYLYRHPYLLAMHRSALGLAGMIAALHIVLSLDQLVRVFLGNLFFGKDSIATASTAAQLWHYPSIFGSISQVLDHGLAGFWGSFWHQTFRYAFLAPTLWLVDKGILPKGQHVHEGKNVTNGAPKSNGVPKVNGVNGDAVKTGAPKKNPPLPTITRLAGIVIAFGQSALLHAAASTTTVATHTLWWSPALFFVMAGIGAGAQAIVLPPAFMNRLPRLIRRATNLLFTIVWLHFTVWLFLDDTSRCGLWLFEPVPFSPLRYIMSIMRGGEMPPIVSPGGSNRAGLSAWRWYSDDLVYWHTGRTWWETGIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXJ6</accession>
    <name>A0ABR3YXJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="625" mass="69608" checksum="CC34D283673EBCC6" modified="2025-10-08" version="1">MDIPRCAPRSQGGRGLPSIYIDDDMPPRSYHDANRSPFASPFSPAISSSIPMSIPNTSEDYRAPPPLPPPRVVPVNGPMSAAAEEYRRRELEPVEEQPNYKTRQDRDEGYHSMESRSRDSFTSARFGMHHDHYQFKSSADAYDNSLLKKLDVRRTFDNRSPPRLGRLSASARDALRPADRFPTLQPLSLPTRMKQPGLGQPLLDSPNRYTDTPMPSAVSPRSTPFSHHYGSDYRSPRSDMPDYDRSPGGARNRRTNSGSITDDASVHDAMDDDTSFTMEETRLRDFHIDTPTSRAGDYHAAGQKRRASSPPGGDEPPMPLYSMTSSEHLRWREGVSRGSPAPRLSANTQDSISSVSSSTRTGSYSSNLSVAATSVTSTAMSLAGGHGGRSPNGGVSPAGGMSPTETAASNSTSTCTSPFASTIPLQVSPRSAAAASRPQQQRIRETAHIVSSPTRRMPDMTKPTSLLKRSEFFIAHEMEKQYECNYCGNRFKNKNEAERHQNSLHVRRHSWSCAALSSYDRAFHESTFRPGEADTCGYCGEEFMRSGFVTGRSDARHTTEQDWDDRIRHLQDVHKFRECNASKKFFRADHFRQHLKHSHAGTSGKWTNMLENACMMEEEPPLPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYH2</accession>
    <name>A0ABR3YYH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="318" mass="33813" checksum="AEF5285EE067AE6E" modified="2025-10-08" version="1">MFLQTTSILAARAASATHLPKDFSLIQTPAMTSALTIDVVVIESAMMVHESVTATVTATTTAVSTTTAVSTYTPSPISYTTSSPHPISTLGSFSSPASDTASFRNHLLDGPRSQGNVSGATIAIIAVFLMILASAICFFFWSPPNKREQLFRYIFGRCKTNKDQNGDVECEGENGRAQSLSRGMEFPTKSPFSSRSISFKNIDLERGDVDVERGMSTIEEEHPSCSDASASTITEDLTLRWPFYPGMTAPPPQPTLPENQAVVDALVEAYSVNTARVAQIVGHSSSTTPPASVVNVNANSTRSTQSNQSNASTSSGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYM4</accession>
    <name>A0ABR3YYM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2264 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049237">
        <property type="entry name" value="DUF2264_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049349">
        <property type="entry name" value="DUF2264_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339:SF2">
        <property type="entry name" value="DUF2264 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20938">
        <property type="entry name" value="DUF2264_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014753">
        <property type="entry name" value="UCP014753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2264" evidence="1">
        <location>
            <begin position="14"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2264" evidence="2">
        <location>
            <begin position="414"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="713" mass="78821" checksum="DF84EDCDAF6422DB" modified="2025-10-08" version="1">MPPHPGFSDNPLRTRADVVKATLALLRPLQQTCFSPEKGRVRIPVATGAHFDEAAAQLEGFARPLWAVGALLEGGSNDDDVLGPWIKGIAVGTDPAHPEYWGNINDMDQRMVESEIVSYALLAAPNQLFYAQPLRVQANIVAWLRQMSGKEMPPTNWLWFRVMANLALLRLADNDKTVGGDKDQKKVLLDQMNADLAKLDSYYIGDGWSSDGSWLTEEQQAAEYEEARINGSRDTGIGRQVDYYSGSFAIQFSQLLYCRYGGADLDPERAERYRKMARQFGASFWRYFDAEGAAIPFGRSLTYRFACGGFFAALAVAQVEDMPAPLNTPGAIKGFLLRHLRWWAAHSDDVFSQDGTMTIGWQYPNMYMAEDYNSPQSVYWCLKTLIAVALRVDDAFWAAEEEPYPEFTGERPAVALVPTPQQILCNHPAGNHHFMLSPSQFVAWPMKASQAKYCKFAYSSAFPFSVPTGPLIQQIVPDNTLVLSRDGRETWALKWKHCEVAKFTEQGWATVRWYPWGDRAVQVDTTLVPPADGWPDWHVRVHRIRVNKAIPMLHAVEGGFAGPGRRSTDGGNIVPATEKPSKLVLGENEEVVLGDNEDSSVLVLSSAGALGVAINKPVLRSSSQSTPTVNARCAHLKPDSNTSLAFQRSLVPTAYHDILDKATGEIAAGTELVLTTKVFAVRAGKDKTDITARWSSKPKVVFDEAGSFNVVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZC3</accession>
    <name>A0ABR3YZC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046112314" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="21"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="246"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="452"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="255"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="477" mass="52267" checksum="C89519309D144677" modified="2025-10-08" version="1">MQLKTLMAVVATLAGMHQAMAQQGLYSKDSPVTQITNKAQLDRIINESNRTSIIEFYAPWCGHCKNLKPEFEKAARSLDGLANVVAINCEDAKDVCRDLGVQGYPTLKIARPPKAKAKGRRTVVDDYQGQRTAAGIVDSLTSQMNNHVVKVTDATLDEFLTSTNGAKALLFTEKGTTAPSTKALATDFLGSIVVGQVRSKEANTVAKYGVTSFPTLLLLTDDDATPIAHEGKFKLKEMVAFLSQAAEPNPPVDLNGKKPKAEKPKKEKKAEKKEKAEEKEKANKEEESTTETPTQQTAPVIVESALPIPTIHTIEKLESSCLSDKAPTCVLVFVGDASSDEASADTQEALNHLADVAHKYAQSKRALFPFYAVPASNPASEMLLESMNLRTTNAYDRVQLVAVNARRKWWRRYEGGAGDISHESIEQWIDDIRMGEGAKQKLPESVVVKAEKAVPKEEKVEEPKAEEPVEEVKHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0C6</accession>
    <name>A0ABR3Z0C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COG4</name>
        <name evidence="11" type="ORF">Sste5346_006268</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="10">
        <location>
            <begin position="230"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="663"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="838"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="948" mass="102391" checksum="537599772D2C6FFE" modified="2025-10-08" version="1">MKNTSDAGGGVGSTNTISASAGGRSRSGSSAAHQRRISVSKRNGTASDSLQSQQNGTSSSSTPPTLTSSLESATSAADVRAALSNLHIREDGLRRNLQSLVASHTDLNRDLMRLDSLRATLGAQVIATRGIATTMLAGAADTAGRLSSTVRNLDLEKEHVEATLRVVEQVAELKACVAGVVGSMGAPQDWEAAAAYLARASRIPESIVKSGFANAVVPTVEVPDPPATTLEDARESLCGLFLREFERAAKESDDARVTRFFKLFPLIGRTDVGLDVYGRYVCQGVAESARNVFRGDAPQAAAGTTHHDSYFFGNALAKLFTHISQIVEGHGALVERHYGGGQMIKVISRLQKEADVQGGIVVDTWSDERGIDRKLTDVKSYPFSFLVQSFGSKGGAGGSSNNNPGGDNSRVNSPALGANGDSARRSEDESGVSMGEIDGLLNEIVIMLSRWSLYSRFLANKCRDDEAEAEAAAKEGAINGKDSRDGKDAAAAATSTEDRPLVIPNVLTQSNLQRKVAARLITPYNLMSTFYFRRSVEKAFQLEEVPNDLSLNIAHAIDNNPPYIISAVDDVMYIVSSVMQKCMQTLQRDVVVGAIPPIGRVLSSDFIGMIQRKMIHEAYPRSTGQNQLPPEDRVIAFIVLINSLDMAMEYLARIVSTRMGVPVDEESSSSAPSGGRESQRAQRIPSPTAPAVVAHLRESFSPFDHDVTLVAAALANLFSGFTTKAVELQNEGLQVLFTNYIKPRLHAIVSDTFRDADYTLDEQELAEVAEMNDEDLDIVLESVSRRFEHGWDGLMRPLARIMTPRTFAHAADLAARYLAKSLERRVWSMGSSGGGGDRGGDRGDRERGERRRNPICAYGAIRLERDVNGIVGAVARGSSNYGARELFAKTTQILMVANMEDDEWEELGGVAANGEGGEGIDDEDEDGMVWLLSEDERRRARGMVLRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D8</accession>
    <name>A0ABR3Z0D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026505">
        <property type="entry name" value="Solute_c_fam_35_mem_F3/F4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346:SF4">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="50719" checksum="F6F4A0FBE408BDE9" modified="2025-10-08" version="1">MARPTDRRSGTPLLHGHASVASRSPSRSDVDRGRADYRTPRRLSDGSPTPASSSASQPMLASARPPISRQSSFRSRSPAAHARLAARKKYAYASVFLVLSLVSFTIQTELAAWVQHAGWNKAYCMLYLTHGSWSMLWPVQLLILRVQKRKEPWATFWRRHVWLVRTTAVMVETRDLSVPQHHQRGGSRFAGALVYMIKATAFITVSLTVAGLSWYVAVNMTSPSDLTAIYNCSAFFAYAFSVPLLKERLRLDKSLAVLVAVAGVLVVAYGDAKSTPEGGEGTREGENRLLGNLIIGAGSVLYGLYEVLYKRYACPPDGCSPGRGMIFANTFGSCIGVFTLTVLWIPLPILHMLGVETFALPTGKVAWYLFLSVVMNATFAGSFLVLISLTSPVLSSVASLLTIFIVAISDWWLTGQPPSFAAMVGGSMIVVAFALLSWSTYKEMAEEEQKKEVDISGGESDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z279</accession>
    <name>A0ABR3Z279_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="542" mass="57762" checksum="B35CA37B76B899A5" modified="2025-10-08" version="1">MQQAHGSLSSPQREPTLQEMYNTWRSLEEQFSQMRRLPMFVKAELKFCHACRILKTRCTCFDYSQLEVGYQERDRVLRHAALREFPIEGGESEEVEGVKTEPTATESVVGTPSTTLTGPPTTPITHQSPALGNSMPTVVKFELRTIIMAKEKIGAQSRRWQCQYGLSDDPSSPVCKREDDNMDTIRRHYGREHGSHRYHKKPALRIRCSHCGLEYDKQRPPIKCPGCKVDRGIWLREIFAVIEVPVPLNSQEDGNGGSGPTYPGGGSSSFGGLGGPVGPGAGDAGGPYGAGGHGSVGVPGSSSRPGGFPGAQVHSIHSACAQQIGSCLVDMVKYDPDTGMPECYNDICNNTAALAVMPPPSVLATPGNTQTHRPSSSSSSSTAQTHPVSMSRSLSQAQSPFTQGFYAVGRGLPLSPSGQIAYAIATPTMSPGLPMSPTSPASNASSAYDAETPTASVASNTEHLGMATGGQGRAHALASSPSTQQPAPSATVSMADVQKFMDMSVTQVAPAVSSTRNRAVANNSSLRIRKCSSESEFYYFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Q2</accession>
    <name>A0ABR3Z2Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="520"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="210"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="612" mass="65104" checksum="DE6835185F0F7EF8" modified="2025-10-08" version="1">MAKAKSPRSGGGAGGGSDSLSNNSGNEAAAAGGENVGLLASGDGHDDGDDDIFGDEHGTGSGNDSLDEIKAPTDSRPTPSRTASGTRLPPNLVTSANGSGSLRTPRTPRTPRTPNRVRFDLRPVEAGPPPTNGHTTSPRDPGGHGDYSDDDDDMDHFDLDNAPENLDRQHRLPLLTDIEAPSVTLARSGEIDTRVDVEEWAERERNRPKSGLSSAFMNMANSIIGAGIIGQPYAMKQAGLVAGVVLLVVLTVLVDWTIRLIVVNSKLSGASSFQGTVEHCFGRTGLIAISLAQWVFAFGGMVAFGVIVGDSIPHVLTAVWPGLHDVPVLGLLTDRRVVIVVFTLSVSYPLTLYRDIAKLAKASTFALISMIVIIVTVVIQGAMVPKEERGSFSRPLLTVNSGIFQAIGVISFAFVCHHNSLLIYGSLKTPTIDRFSRVTHISTAVSMVACMLMALAGFLTFGDKTLGNVLNNFPADNTMVNVARLCFGLNMLTTLPLEAFVCREVMFNYYFPNEPFNMHLHLIFSTSLVVSAMTLSLITCDLGAIFELVGATSACAMAYILPPLCYIKLTTRSWRTYVAIGTVVFGCAVMGISLLQAVGKMISGEGGNAQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2S8</accession>
    <name>A0ABR3Z2S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF5">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="164" mass="17572" checksum="92E657A6050438DE" modified="2025-10-08" version="1">MAFNWVLILRAQQLVFSLIVLGLSAYVVNWYTMDTRTASPTQVNFLVAVPVISLVSLAYNEGVSRFAPRAYIAYVAIGIDALNALLYFGGFIALAVFLNGLLFCRGNVCGSARAATAFSALSFGAWTTSAVLVALGVFRGATRKPNPRTQGMYAAEMKDAASRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3A7</accession>
    <name>A0ABR3Z3A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GPI18</name>
        <name evidence="13" type="ORF">Sste5346_005525</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 12" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="474" mass="50761" checksum="4543FDB64B91CD91" modified="2025-10-08" version="1">MASASVKSGGVAVTKSTPAILNYHHYPYRSLAIVFTLWKSFLLAIAVIATLAGPAYDTSGDLLEAAEKLNVTAPYSLAAGHGIPSGGIVSRLTSWDAIYYVQAARRGHLYEQEWAFGAGLPLVVSFLRAALSKLGVDAPVALVAVVYVHIAHLLAVWVLYRLGCQLWIGTAGRTTAFVAASLHILSPAGLFLSAPYAESSCALFSFVGYSAFASGRKQGLSVKGDLLRLLAGVSFGVATLFRSNGLLNGVIFAYEAVYGAVTFLQQPSLPLFRRLASIGLGGLAVAAGSVIPQAVAYFQYCSELSGVPGEELRPWCAERLPSIYNFVQDHYWGSGRPFKYWTLSNLPLFLLAMPMLLVMARSGLDLWETATKTKDSNGKPSTAVGADNVDPRLSALLQCMAASQLLVAFMAFTSYHVQIVSRLSSAYPVWYWWLAQGLGRGDASRSKLAGGLVVFMVMYASIQGILFASFLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3B2</accession>
    <name>A0ABR3Z3B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RRD1</name>
        <name evidence="12" type="ORF">Sste5346_005518</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="458"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="572" mass="59998" checksum="5049C0AD99010528" modified="2025-10-08" version="1">MAYSAPGAPDEPAQAQAPNTAPTTASTTAPSTILPPPPRPASSSTTPTPPLPSVPKLEILPGGDKPSHTFLRPSKCINEGPDVARFLVSKAYRDIGLFVLQLNHALCPRRKLSSGPSTDNERPTASTTTLFTLQSPKRSDDPPSVQKLQALLTRIAAIIEEAPPDPGPRRFGNASFRTWHKLLAERIEGGLLEEYIAIKGHASANKTEGGNGDDAPAQAMDEVKAYFLGGFGSAQRLDYGTGHELSFLAFLGCLWKLGVFADGDPGTDGEAVERSLVLGVLEPYLHVVRRLILTYTLEPAGSHGVWGLDDHSFLPYIFGSAQLTRPIAFLGNESMPQEGSAPRVPKPSDIVKPDVVATQRECNLYFSAVGFINDVKKGPFWEHSPILFDVSGIQDGWGKINKGMIKMFNAEVLSKLPVVQHFVFGSLFSWDEDPAAAAPVATMHMTNQPVATAHISASLNKGPGRAGAVPPSSALPPTGMPGSGGVQTATGAPWAQATRMPGAAPGALPGPGIPYSRVPMGTARPGAGGPGIGSRAPPTAFPRLTQESQLPGAAGGSGAGQDTVVTKAPWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3H9</accession>
    <name>A0ABR3Z3H9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="3">
        <location>
            <begin position="156"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="353" mass="37297" checksum="E7E752E25E042B4D" modified="2025-10-08" version="1">MPAVALLGAGIFAKEEHLPAVEAASDLTLAAVYSRSQKSAEALAAAATQGPKPDVYYDSPATEGKSLKDLLARKDVDGVIVSLPILVQPAVIIQALAAGKHVLSEKPIAKDVAAAKALIENYSKIGSGAPIWGVAENFRFLEVILYAASQIRKIGGDVTTFSMKMNTLIGDDDKFFNTEWRKVPEYQGGFLLDGGVHFIAGLRYLLGETEAKHDISKVSAFTTLLQPKLAPVDTVQSILTTDKGAIGTFCVSFGTEFKSAFEIEVVTTKGNVTLAPTAVTSTWVETAGGEKKEDKKEFSFSAGVKPEIVAFAASLSKGVVDPRQSPQQALKDLAILEALLASADKGGAPLTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K7</accession>
    <name>A0ABR3Z3K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005366</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF24">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="41"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="500"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="59460" checksum="318CC02AAF8861CB" modified="2025-10-08" version="1">MFHVDKTAVRGVHGDGVVLRDTDTRDRFWWHYPNLRMLNILLLGCIVCDITNGYDGSMLNGLQSLESWQDAMGHPEGTRLGTLTNGTRYGQLGALVIAAPLMQRLGRRWPIVIGSSILLVGVALQAAAANYTMFVVARVLIGFGNTIQNTACPVLASELAHPTQRTTIIGVQNSTGSLGQIMAAWITYGTAFLGMSSWSWRLPSLLQALSSIFQLCMAFIMPESPRWLVHKGRTQEAYRILAKYHAEDDETSRLLQYEMAEIEAAIEAERAQATSAWSEWIRTAANRYRLFIIITSGFIIQWCGNALISYYIHLVFNSIGITNPKTQLELNGGITINGWVWGNFFSLFVDRIGRRPMWLIGLGGMFTAFLLLTVCTGVNTGTNYSNDNLSRTTLFATFLFGFFYKMPGCMLNSYVAEVAPFELRAKAFVLSSFCDAAANIFSGYTNPVGLAAIGWKYYIVWCAILVSNFVIVFFWYPETKNLSLEEVSQLFDGQALAPENSKLHDEDVPAEATATEVGNAVDGAPESKEAKVAAQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4B6</accession>
    <name>A0ABR3Z4B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="48"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="175" mass="19944" checksum="7D49BDDE853888EA" modified="2025-10-08" version="1">MADAPTTTSGDPAPVDHTFTHTHKLAYDKGNPPNRQRYWRINMYFNKKPGISDEYFTNHWHHVHADLVTGMKSFNKLNLLRYNQFFQEAGAKKAAEAMGYGPVLTWDACTEFWVHSIEDFVAFTKSQEYIDATPDMHNFCNVEDGIRIMAGYDNLVFGEAVPGYGEDGVVKKDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4K6</accession>
    <name>A0ABR3Z4K6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Presequence protease, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pitrilysin metalloproteinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CYM1</name>
        <name evidence="8" type="ORF">Sste5346_005347</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running. Preferentially cleaves the N-terminal side of paired basic amino acid residues. Also degrades other unstructured peptides. May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer and homodimer; homodimerization is induced by binding of the substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="7">
        <location>
            <begin position="490"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114219" checksum="4CE7578FD85EEA66" modified="2025-10-08" version="1">MLRHATAAKAASRHVSRRAFASLANAPTTPGEKLHGFTVVRSKHVPELELTALHLQHDKTGAEHLHIARDDANNVFSIGFKTNPPDDTGVPHILEHTTLCGSEKYPIRDPFFKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYMDATLHPLLKETDFTQEGWRVGPENPQAAADALDGKLVFKGVVYNEMKGQMSDAGYLFYIRFQDHIFPAINNSGGDPQKITDLTYNQLRQFHAEHYHPSNAKVFTYGDMPLADHLREIDARLSSFEKIGRDAEIRLPINLADKSESVTLTGPTDPLVDPSRQFKTSVSWILGDTTDVVESFALALVSALLMDGYGSPLYKGLIETGLGIDWSPNTGYDSSGRVGIFSVGLTGIQEADVARVKDEVNAILRSVRDKGFERSKIDGYLHQLELSLKHKTANFGMSLLQRLKPKWFTGVDPFDALAWNDTIAAFEAKLAQGGYLESLLDKYLIGRNTLSFTMAPSATYSQELVQEEETRLASKIAEVAQKSGGEAKARQKLEEQEAVLLVEQGKSNTEDLSCLPTVHVKDIPRSKEPVVVRDEKVDKAVTVQWREAPTNGLTYFRAINALGDLPEELRSLVPLFTDAIMRLGTKTHTMEQLEDRIKLQTGGVSVGYHSAASPIDFHQANEGIMFTGMALDRNVPAMLDLLRTLVLETNFDSPEAVQHIRQLLQAASDGVVNDIASSGHAFARRAAEAGLTRSAFLREQVSGLSQVKLITSLASRPETDQLDDVLAKLKKIQQIAMQADSAGSGIRAAITCGTESVEANSSALSKFMSSLPAPTNIGTSAVSAIEAAKRVQRAFANPSEDKLRQTFYALPYQVYYGALVVPAVSYTSPDSAPLQILAQLLTHKHLHHEIREKGGAYGGGASSNALEGVFGFYSYRDPNPVNTLSIMRDAGRWAVEDREWTDRDLEEAKISIFQSVDAPRSVNEEGMGQFLYGVTEELRQTRREQLLDVSKEQVRDVAQRYLVDGLAKQAEQTVFLGEQQPWVDPKAWNVEEMNVKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z546</accession>
    <name>A0ABR3Z546_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RDRP core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="481"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1546"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1340"/>
            <end position="1349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1580" mass="178283" checksum="0FFB0A4B82275AAC" modified="2025-10-08" version="1">MAGGAPAGRAAENATGPNKKAEISPPGAEGKTPCSAGWKSGSFVVMTIILRNLPPQTTTLDIYKSFMPLAITSIDILEDSRGERTGTARVRLTPPDHDYWYDCCWRLELEDPAAPVPYPRVSAQVDSKGFRKAAEKSIRTPLNHWVPARKEIELAMLGQGFMRQKRAMMVMDEVEHDGESTLIKIRLHFGRRDMSIFVTRFLQEAGPENDSSPFPHPRLKTEYRIDIRFSWIKHIWEQSFPNGRLCVALVLDSPPEYWRITPDATKTHGSDRNSWNNKERWVRMAYLTMNQRAVRDAAVSLNGVFPKGQAVDLGRWTVFRFGFSPSTVGDWQDVVGYLRDYDLRPKPCPEFRFLPRDDRTMWDCLQTNDTAGPGGLSGSASSNMHHLSRRLSYEVAYQLEVCISRNILNETTLDVVFLESLAALTPDRATRMLEYVAEHGKRIYQPHSIFRDPRAASYWRKSPPDAALDKDRAVYIRKVIVTPTTIIYSTPTLEPGNRVLRHFREHHDRFLRVQFTDELLIGRLSGGRDDQRSDDCFLRAFRALKNGIRVGGRYFEFLAFGNSQLRENSTYFFAPTDLLTCQHIRDWMGDFSSIKSIAKYAARLGQCLSTTRPVPTFGVPTTVQRIADVDHGQFCFTDGVGKISKWWARVIASHLREDDVPSAVQFRMGGCKGILVVWPDVPLGQVVQIRPSQEKFPTLDNANILEIVRCSETATATLNQQTIILLSTLGVKPQIFLDLLREELAGLEAVMKDPHKAVDQLMVRVDQNHITPVLADMVKAGFMTSDEPFVWAMLQLWRSWTLKSLKEKARITVEKSAFVLGCVDETDTLRGHTQKKPGDEQPKLPQIFLQIPDLTDKVQGGVHILARGNNRNYGVAKGATKYRVITGLCLIGRNPSLHPGDLRVVEAVDVPALHHLRDVVVFPRTGDRDIPSMCSGGDLDGDDYFVFWDERLLPPRKFWNYEAMTYDATREPDVDNVTPRHLIQFFVQHMKHDTLPRIAMSHRAYADQLEGAAMNPRCLELAQLHSQAVDYAKTGVPALMPHRLSPKKWPHWMGRTFKRTYRSWNTALGQIYDKVQVETFEPAYDKTFDQRVLGHYPNLDTKMLHRARRIKTQYDLVMRRAMAQKELESEFEIWSGFAMKKPRVGSDYKMAEDLGRLIRVITHRFRRVCLREVGNSQDISKLGPFIAAMYKVTSEEVRIALHEFTLANERTRPTTTLKEGEAPPPLPRLGHTIAPLISFPWIFSHELCTIATAVDQAREAEAEKEAEKETEGGGKKEEAKKADKKGTHEKHDHFLTPSELAAMEYRIIKGVHTHYGVPLDISSYDGSLKEEAEGEGGAVDSNNSSNTVKADTGEFEPMWTLPPGKSEGDVVIELVASTKTENDDDDGDDCDGSDMDFMMHGAGGQQQRLLRQMKKSMSGKTSVHFPWAEMEDDILSTTSEEDDDSRDEMKKGPETIVINRDDDEEEVPALLKTVKNEEVKTEATVSATPPIESLSLLDALDEPLPMGLPQDVHIPITAPPLDTANDADDEDDADDDIFATVDNMFGGSWNKGKQVKKEKQASKGVKNKQALLDTENASLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z582</accession>
    <name>A0ABR3Z582_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046424834" evidence="2">
        <location>
            <begin position="16"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="130" mass="13536" checksum="89B176EB4B94EE97" modified="2025-10-08" version="1">MRLLTLFATVPVVAAVDYGYWDVAITRGWAASGYKGWTVAANYSGTPGITKHGSFNHNPPPNMGDVTNQDPDFEGVPADNNQVRITQLVVLPDIGSVNITGSGQISCAINEAGRGCSGSGRINATAVTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z680</accession>
    <name>A0ABR3Z680_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nitrate reductase [NADPH]</fullName>
            <ecNumber evidence="2">1.7.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_005189</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>nitrite + NADP(+) + H2O = nitrate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19061"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="1253"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="885"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1211"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="900"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="930"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1061"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1115"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1211"/>
            <end position="1228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1814" mass="201559" checksum="9270EB4002B19B72" modified="2025-10-08" version="1">MLFWPFVTKTHVDPGSADAYFLDDMRGQSFSGQALTGESVDNQPTGDLSFASPTLTRTSHIPRPGRRAIRSDDPEFLNFVANIQENLKNQDDQWTVEDIAADLGFSQHDTDLLFEVTPEQNPALFRQQEELRKKYYEALKRAMCEDDESRHFFFSMHYNSSRAQALTLAMFYFGVPAPPLPARQRASAAHDSLSFSDAYTPDQSARSMVERPAPPLAGGANTSVDPRPKPEMKSVYVSAFGKTCSVRTTSGFLYGRQGAVRFDLEDLSSFQDAVVRLMGATRAVHVILMKRAILNRLERLTTHGQTFHEIINNSPTADPFCFDKIRYMILESRHGIESDDVDIGWVPFVFLEDEQPPKDHWRPNTEPVGLIKCIRRGSPTSSLRPNSGDVAYVGFTAPFKVVEDKWYTPRYRLYSNQYGPWFQVVARILTPGAGLTILKGKPGSLIANCRLGLVVDRFKEDLVFGSLYKPFSTHGGLGFLDQHTGLIANAVAAVGFVSNDDPENDYNDNEERYVEFEVDPLPEFGVGVFLAGLSSDETEAATAGVNTDEEEDGDDITKRSFRASLARCIDRVIEAGTTLDERKLIVGVDIWPDGYFWNSNDDNNGPIRPIRVHGPSCNPADLSDIDDHPQDAPSVVAIRPVFKTYTAHVRAPDKTEGSFEFTLDGSFKAFFASVVEAMGSSVFDAWQHTQGKSQDHSDYLEYKEYQELRGRAADIVDSRRELNHLWILQSWKDAATGNRPQFLVSRKTTTQAEWVRVCSQIVSPEIWVVREDRADWYEKDLATPSAWGYQAAYENLLSLDEHEKRWQVLYEKRMQSQLEPVPARDVEKGDTADSATSLSMCTFCSHQFSANDTDTDKLRHMDDQHNALRRADDTPAQLDVVVTQAPDDTGLATPPQQRTPPKKRTRSRTPSRLDPCYRPPKTRAKEESDASSSGEASGSSDKGTRAAGKKRKIAARRSTSNDDPTYRPEGDEDDEKDHDLGSAKFVPDDFGYEEGKKRRRTAPKINDPSYKPSEDSEDEKDHDLGSAKFIPDDFGGGPRGKKKKTAPKVNDPPFKPAKDKEDEDEDNDEDDMDDKKKVTPSKKKLNDPSYHPGRDAGAVDVDDLDDALRQSAVPEYDRDPTDPAGKRLRVIREARGRTLRQRKEKEDTNSAVAVTIAKVALKGKVKGVSKAALKDGPKRNDQGKFTLYAGVSLVSVLFALSQPLSYIHIGHHDDHGDTKHGGDHDGSKKINTGDTPPPPPSPSTGDDQRDPNLPRFRLADVRKHDANSGSPWVTSGDKVYDITDWVAAHPGGDVILRAAGHSIDPYWAIFTIHKAPHVREILDSYLIGFVDVLDLDTSGQPKIAAGEGVEDPFAADPKRDERLVVLTQKPCNAEPAPPQLARDFTTPNELFYVRNHMWVPVVEKAEAEQHRLTVELPDGEVRAYTLDELRSRFKKHTVTAVLQCSGNRRSDMTRSVGKTNGLQWGAGAISNAIWEGVLLKDVLADAGLNAATSDQRSKGGQDEDDEVPPDGLHVQLTGMEAYAASIPLPAALDPRGEVLLAYGMNGQPLPRDHGYPLRAVVPGFVAARSVKWLSKIIVSDEESQSQWQRRDYKLFGPNEGGAPDWDKYPAIQEMPVTSAITGVWVGTKSISKAVKEGHLTAAFSSGTAARAAPGVRDLPAWQKEWKSHVNESKNSTPVTATGYAYSGGGREIVRVDVSVDGGKTWDQATLLDQKQAEYDDETDRQKRHIVARGRRDFAWKRWRYDGVLLGDSPSEVVVKAIDSAYNTQPEKHDGIYNVRGNLATAWHRVKIDKDAKGKNPVLNGCGFDKKECKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6M9</accession>
    <name>A0ABR3Z6M9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="122" mass="12801" checksum="0FD8BB52A9169358" modified="2025-10-08" version="1">MSFSNAVTDLVRSIYEAIAGIFHLVFRVLHGAFSTVAHSFEAVINFVVDMVHSSVALVGGVGKFVAGNFVILAILAVGAYFYLQQSPEQKAQLKSSGKQALGSAKAQANAAGNRVASKSKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7V3</accession>
    <name>A0ABR3Z7V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="648" mass="69338" checksum="9627720EB5A1B82B" modified="2025-10-08" version="1">MPAKQKMSAGTTSSFSSANPGEARPRGKPRGRRRDRDCVTCKTRGLKCDLNRPQCLPCVQAGLSCGGYPMRVVWQEERQRPTSSASANKVTKPSRAPAPTSTSAATSARRASTSPTPGPPISSSPTFSISPAQQQQQQQLPQPKAQPQQQPSPPPPAIMPMSPASSTMSAVYSQLIEKPWCETDQNSLIKRLAALCNDILTAEAQAPSAGATEEDVSNTHPHPAHVQQTSSSQTIVPQTATGAASAAALPSSSTTIATDTRNNTTTTPSSAPPLKHRNQYLSLPETTALLSDLCVFIQARLEGRSLAPRQQPPDSLEMVKHRLAALAHVNRAIAAANPFAFLGIATFAVFEVCDDTAFGEWQRHLYGARHLLDYHHCQTLADLHRLAAMVPGLMDILARLVWFDLSGAVVHGAVGGPFQAVTSEEASGDVFSLTVSAPAAPATPLTPARPGLIFDDWHRQVLLDDEFFATVGMSADSCALYVDVAKGHLARRPVQACLRAAEQILLVAPGPGLSDWELSANVGRCAAALAALSQAQETRKEMMEDMNDDDDSAEEDSRWESTTAAAVDKLCATLAATPASSRFYIHLAVGAYVGGMQARTRAHCEVIKQYWLNCNLCGISRYPGGLARCEEHWRRIGLLGEGETVSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z865</accession>
    <name>A0ABR3Z865_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018465">
        <property type="entry name" value="Scm3/HJURP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992:SF5">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10384">
        <property type="entry name" value="Scm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="628"/>
        </location>
    </feature>
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        <location>
            <begin position="634"/>
            <end position="644"/>
        </location>
    </feature>
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        <location>
            <begin position="671"/>
            <end position="702"/>
        </location>
    </feature>
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        <location>
            <begin position="716"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
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        <location>
            <begin position="837"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="877" mass="93687" checksum="B429759A0931ABF5" modified="2025-10-08" version="1">MEPPAKRTRVGRAPHDAPADDNNVDIGNRMSSNKGKKSSNAASSKPKNGEDEDDEIAMDPEDYAMKVDPEYRLDRNRANADNKLKSAFELLFEKYSQDFGDTGDEINFYTDEIEVDNGHIASLPVERPSKQDDQDSDEESDEGGGETDKLPALSAAAKAASSRLVASLLPSRFGPGGTVIMGGGSSAARGLAPGEVDPTWAAPELPDSAFTTPGGGFPFIPPPPPPPPRTSYVAPQPTVFTKALPTSYGEDLGEDGEDEEDDLIMDTPNPMMKESRGENSSPSSAAPKAPEEQPTKSRRKRTSSRPSTADDATETADIPAAPKPSASKKRKSVRNGEKPAPPTEKTVVPDSQSSGLDLSEMQSSAPLPVSFEEEISQDGPSSPAAQGSLPTPPDEDVKSEEQPASKEPNTDSTKPKSKVTFKQNKVDPSFVFSDEEDFGLKKRKRKQPTSTVPAIPVAEPAEEVPVAENEVVQPTPSLDEGKSPLAAPVFEKKEQKRRGRPRKSNGTEAVPATIQTASEVIESYDLPEAQRRDAQSLSIIIMTSSRPSSALPTPALAEAAPPVDIESGPETTAEPKVESVPEPEPEPEAEPESEPTAPPVSEPIEPPAATEPEPRTTPEPANEPKDEAVIEPGLETEQDVEMDDSTYAPSPPEETSEEQPKKRKRRRQTEEQSSPLPSSQKAAKSARSLKSSQKSASSFTKSKAGRHRTTREIPDSQSIGSSGIISLVSDGSADEAEIEKIAESSPRPFVPGSGGRQPVSVSVSTSVSGSRRGSPQTTPTSRSHQTTPSSRRRLTAAEVLMATPSRHRSYNKAGRLTPTANRLLLLSPLARRHPQMSGTSSAASSPGGSPVQTPGGTIRRCGKDGFRCEREFCFRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8M5</accession>
    <name>A0ABR3Z8M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004227</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="79"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="23701" checksum="80057A327E49A021" modified="2025-10-08" version="1">MANTPFPTSNRVVAWKSATITTSAGTDNSAKGTSNDNVVNAPSSSIDNALALDTVNAAESHCYTDTDYGRVLWKIGLILLPVMWFCYGTQQADNISVSTKATFSLKTDTHLVGQQYNWLTTIFYLAYLVAELRGNYLMQRTSLRWTLAGCMLIWGIFVLCIGFSNNFATIMTLRALRGAAESTIAPAFLLITAAFYARREHALCTIIWGSELGNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8M7</accession>
    <name>A0ABR3Z8M7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lsm8</name>
        <name evidence="9" type="synonym">LSM8</name>
        <name evidence="11" type="ORF">Sste5346_004636</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="100" mass="10817" checksum="9794489E766DD764" modified="2025-10-08" version="1">MAALLNNYLEKKVLVLTVDSRILVGTLASIDNSTNLVLLGTVERVINTPDDDEPSAEVPLGLYLVRGDNVCSIGLVDEQLDASIDWTKVRGQVIGTTKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9P2</accession>
    <name>A0ABR3Z9P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Squalene monooxygenase</fullName>
            <ecNumber evidence="4 10">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ERG1_1</name>
        <name evidence="12" type="ORF">Sste5346_004121</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="8 10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene epoxidase" evidence="11">
        <location>
            <begin position="82"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="380" mass="42347" checksum="6AC198A7ED5BDFF8" modified="2025-10-08" version="1">MELCRSALHHLLYYDTILLLDMFFFGSCYAPRPGIYGFVANVGGIVDDCARHVCLGWRQHQDDEDGRPATWDERKGVGLLLAPLSIVADGYNSQFRDKASRKVESRSKFWALELQDAVLPSPGFGHVLLGDFSPVLLYQIGSRETRALFNVPEGHEYAKSTQGVKRYIENEVLPNVPASIQPSLAASLEKGRLRCMPNSFLPASKNRTPGVLVAGDALNMRHPLTGGGMTVALNDVVLLSELLHPSQIPDLDDVARVLQQLNVFHWRRKRHTFVINVLAQALYSLFAAHSYYMSILRQGCFEYFKRGGICIDVPASLLGGLAKKPLLLVYHFFVVAFCSIWHLFLSKSLVLLPLTLVDSVVVLVMACWVLFPYIAMELAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA62</accession>
    <name>A0ABR3ZA62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF27">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="15"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="511"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="545"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="615" mass="67698" checksum="D459F5BEEC205143" modified="2025-10-08" version="1">MLQDTYLVCAFNASLIVHVPSFEQADSRGSVPRHTLLAMHAYAAHFISCLPPHDKRHHALAREVGDVRRVTEGWALEAGQLALQEADQPTLYMIQTCQILSLYWFSQGDSKRNTMFSGIGYRAVRSTVVDSRDTLIPASSPSHRLGPAQPVDLNAETLKRLFWASWVTNVINSDHYTPGSAADTLVLTLPLPVSEDIFLCSTDEPETASPAPITIAQSGGNRGADHDDGHNNTQLQTPSIMAEIMKVMMIWREAWVNAFSLQTDIANWASQLHPDLTYSKRNLYRQLVVNQQPIYAMLHALHHQCYLVLSASLVPHFSGLVMARDMPREVVQMSAAVALRSARSLSELGAHLLALEWDPAHIAPFVGYCMYVAASVQISVLPKSSTGSGAAWGNMINCLKLLKLMKLYWAVLDKLWARILRLYDAQVASITTVPITPAGELDAEQQEYLESPERPTGDLEEPLEDSVLHYSLRNLKTSVSTSGGSPSAQGLETAVAVGANRAIADRVMQGNAPTMGPVLAGGTRQQPAPQNQQQQQHQQGLLETLASTLSPNLFPAQPTQQQQHNPESLESFNNISQSPLMSFAPLDVHSLDEYDWFQLDMDNSAQVREALNGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC05</accession>
    <name>A0ABR3ZC05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004238</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="62"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="57660" checksum="62D571659BC038CF" modified="2025-10-08" version="1">MADLKGLTSTKNDLVYSSTADVSSDDEVRPSEGKRTWRSFFWSSLDVSKEEAYFLTKLDLTLISASALGVMCRYIDQVNITNAFNSGMKEDLNLYGNQLNYANAIWSAAYVFGQVPSNLLLTRVNVPLYIAFLEFSWSAFTFAHAGVKNVNQLYCFRFFVGLFEAGHFPAVMYIASSYYKPHELARRNSLIQVFTSVGPLFSGFLMAAVYAGLNGVNGIAGWRWMYIICGAISVPCALWTAVAMPQLPSRAKANWIFTEKEAQLARARMPTEKKPLTGLFKWKDIKRWHKTWHVYLFPLFFTFLSQWGQAGGSMIFWVKSYNVTGKPLVFSVAEINIIPLGINLLTIFFTLTSSWISDSLPKSQRWPGMLFASVMAIIFPIALASTPVHPTHIASRWVLYYLTSLAGTCAAITWTWVNEVNRDDPEKRAYISAMMNAFAYIFTAWVPIFTFPTSKQPYIVTGNYITAGFGAGGALTVLTMRWFHNRDVARKEQAAGTVVEDVEAPSSSIVGEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCT3</accession>
    <name>A0ABR3ZCT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003707</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="85"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="605" mass="64326" checksum="6EC80E3B4D4B0C97" modified="2025-10-08" version="1">METSTSSSGVFDIEKQSEIDTVPHATALKDTDFDDTLTRQLSKAKLENRPRQSTPDAPASDGENASSAIESPGTEEITGFRWILVCIALYLSTFMYGLDTTIAADVQSAVVETFGTVGKLAWLGAGFPLGSIAVGLPYGSLFTHFNMKWAYIGGIVLFEVGSALCGGAPNMDTLIVGRVIAGMGGSGMYLGGLTHFSALTSPRTRGAYITGIVFVWGIGSVLGPVVGGAFSDSSATWRWAFYLNLVIGGATAPIYLFYLPAVTPPSVAAAEANGTLLPVRTRLARLDYVGFLLSAGAWVTLTLALLFAGTQWEWSDGRTIATLTVFGVLFVGYILQQYFCLFTTPETRSFPGHLIAPGTSGARTQILLYISTSASITTMFIPTYYIPVYFQFVQNDSALIAAVRLLPFVLIAISTNLASSFFLRLVKYYMPVYLGAGILITISSALLYRYLNPDTAISTIYGLTVLGAIGTGLLVQAGFQVGTLVIKDPADMGHVISVQNVSQIGGQVLCLVIAGQIFQSVATNKLRAVLSGLGYTDADIQSAVAGSRSALFESLQGDLRDRAIRAITEAIQATYVPVLAAGALIVVVAICMRREKLVFQHPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDX6</accession>
    <name>A0ABR3ZDX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulatory protein sin3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SIN3</name>
        <name evidence="7" type="ORF">Sste5346_003493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="6">
        <location>
            <begin position="723"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="297"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1013"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1428"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1569"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1016"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1053"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1070"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1443"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1464"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1480"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1519"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1579"/>
            <end position="1601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1619" mass="177968" checksum="A1D1E125206A373E" modified="2025-10-08" version="1">MAHRDRERDPRDMQREPYPPQPPPPSQQQQGQPQGQQPHHSSAGSIPIHQPVASRISGAIHSPNGLLANHGAGAGGAPPPPQQQQHGGQPPPQSGYGGPPPPMHNAGGDPNRPHPSVQDQQQQHQQQQQQQSMYYNSGPPPPNGAMGPSGGPPPGFGGPPQPDNRSGQQPPPSYGAAGMGPPGPGGPPPAGPPGSQSAQQPAGPGVAQGQQPILNDALSYLDQVKVQFHEMPDVYNRFLDIMKDFKSQTIDTPGVINRVSDLFSGHPNLIQGFNTFLPPGYRIECGLENNPNSIRVTTPSGSTIHSIGPSRNLPQGNMFLGPRSWAQPQPQPQQQPPPPQNVQHSVEGPEGQYGGPGQSIPQQGPGPYGHGDAGSAMYDGPRGPQGGPSGPGGPGGPGGPGGPGQAAAQPPVPRSTHTGAAANGAAAQQASGEKRGPVEFNHAISYVNKIKNRFQDKPEIYKQFLEILQTYQREQKPIQEVYAQVTTLFSGAPDLLEDFKQFLPESAAHARPAGGRPSEDAPTAAAAVLAAQTTPPSQTARDGPKMPPVGNFAPPSSTTKENKKRPRQDKQAPAPVPPPVELMAASTSAVRGLPTVAANKRAKLAHKGALDVAPLVEPTLTPVMPGPLPRVGFIQDTQDGLNFFERVKKFLPNRTTMNEFLKLINLYRLGLIELNVLVTKSHSFIGGNAELFNWFKNFVGYTGEDEVVDNQPAPPSGKVSLSNCRGFGPSYRLLPRRERLKRCSGRDELCNSVLNDEWASHPTWASEDSGFVAHRKNGYEEGLHRIEEERHDYDFYIEANQKFIQLLEPLAQQMLTLAPAERESFRMPPGLGGQSTSIYKRVLKKVYGVDKGADVANDMFAHPFAAVPVIMTRLKQKDEEWRFSQREWEKVWMAQTEAMHLKSLDHMGIQVKSADKRNLSAKHLVDMIKTKREEQRRAVAIGDGKAGVHQYLWDFSDRDVLLDLLRFMILYVLNSGQHGAAEKERITDFFETFIPQFFDLPEELVLQRLSDIDRDSGDEEGEDGTPTELTNGRTRRSVKKSDLLRGVLDPGRNGNSKSGSASRHTKEDTTGSGSKETTPDVNSANEEEMPDAPPAADERTSALELASDHWLPAAPKPTVVTGENPLTVDGDLKADGLFKRQWYNFFSNQTIFVFFSVFHTLYKRLKDVKESGESVLQELSRENAEKPGRSLGMMQEPMSFFDAKHPEQFWPQTVELVEDFLTGEIEESRYFDVLRHYYLKKGWTLYTIQDLLKTLCRQALVCSGSDSREKTPDLVQQFLTSRQQEETSYEIEISARRFAEKCIKDGEMFQITWYPAKNEAAVRWLQRDEPTFNADTMALQERWQYYISTYMRIEPTEGVDKSRLRKSVLSRNLPNASENDSDNGDSRKAVAFNEGLIMRVCLNSFTLVYEKNSSEFFIYNHDHDVEEIEDDDQDGEAAAADAQADEAEDEADEAGQDKKKAKMAKKDADGADAEDTKAESSNADTSADAGADSDEKALQKKLAAQAARRAEHRRLRAKKKEDQTRRRQQYREQRFREKFVINNAWMKDKTQEEVRSQTDKFLRWVSEGALPNGDSVAPTATAGSSNGVSSSTGAAASSTDASKTKIEPTDGGAAMDTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDY4</accession>
    <name>A0ABR3ZDY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="312" mass="34678" checksum="226AEB05C009B0B2" modified="2025-10-08" version="1">MIMRAPFRPVQPVIWINGWPAMGKLALAQCICQLLGTDRCVVIDDREFTDQLKLPRDALMSRCVSRSGGRPRGLSLNDINSNTHTHRYNVCGEAGPDGGRCPGRECPGRGCPGRECLSGRLMTGQDGLMPPLQIKQAACFRKFVYGDEDDEALKAGKFDAIQRQRVVIFTDCRANNKVGAEGAWHYANTVRDAGRDFVPVYVECLPEEHERRAKMSDKLYNHLDGEAMTGMEASRELQARSDGRLFTFPQDKIPGLYLDVTTQGIHDSALEVISFINAIHEKRSDFIKEKCEASARRRPGSSVESGSESNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEH5</accession>
    <name>A0ABR3ZEH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051635">
        <property type="entry name" value="SNAT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10908">
        <property type="entry name" value="SEROTONIN N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10908:SF0">
        <property type="entry name" value="SEROTONIN N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="63"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="227" mass="23351" checksum="B987E5248882C804" modified="2025-10-08" version="1">MASSTTSIDLSAPGAVTIRPLTVADRDACVVVENACFTNPDHRATPDKFSYRLTVCPELCLGVFVHTADSEALLPAGSSSSSAAPSSGVMVGHVIATRCGAEVLSDASMGVPKDWRAAVAAAPAGSDAASAISSPLGHQAAGSTVAVHSLGIVPSLQGKGLGTKLMKAYMERMAALSATAGAQKIDRVALICQDYLVDYYTKLGFKNNGPSEAQFGGGGWFDMYYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEY2</accession>
    <name>A0ABR3ZEY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF7">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="424" mass="45126" checksum="8A463916D3FAA604" modified="2025-10-08" version="1">MSNPLDKLEALLHQHPHIQYASPSSSGYAELREAYILGTEARPLAIIRPQNAEDVALLVSYAVAERIPLTVRGGGHDLFGRCFATGAIAIDMRDIQSVHISADKKTATIGGGILATDLAGELGRHKLATAVGSAPTVGWVGWATHGGYGPFVANYGLGLDQILGATLVNSKGEIVEADELMLATIRGGGGSIGVIIDVTIKVYPLSKATDDLGATLSKFTEGYQQLAVPDLPDALGIQQSFVNTPSGKVFTVVFVWSSYDLDLGYVWLDKIKSLGTVIHNSVVPTTIQAWLDDSGKFVPKAAYGGNCTVSVRSFTDEVVAVVAEHIAKMPTDSATLFSAHLLRGTSAAPRADSVFGARTPHYVFEFIATSSTTEQTQASWAWATAFRNAVRQTRADNVCSFTYISLTPPSDANYASIYGPSWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFK1</accession>
    <name>A0ABR3ZFK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="468" mass="50783" checksum="502672B66E73DA62" modified="2025-10-08" version="1">MVKSSIGGRFAALVPTDNCSVADTSIDDHRTEKKPSRETSPAIKHKSLQAPEPNNATAANENWRPHVSTVTEKSTGSTDSADSMSSPLPPKTAETKGKGKSAANPNTNTNDVDSRHSPQPRGHYGAQAAQVAQALACIKARFIAELEAPDNSSADLATDSADSMPDPPPKTADVKGKSAAKPKTKDVDSRRTPRPRVDYGEDALANLIAHIEAEEGRDGWDVLNEAIGININSETGGIVLMKPLEPTDSESNYATKEAYLRSMAELPLFFIPDPEYVEKIKSSGKSGHRHPPKQNPDLFFSLPSQSRLPPYAMLQSQPRTHLPQDSEGWSRNPLENHPAMPFLSPRLQDIARKCLRPECGQEGREVADFIMNRCAGSENIEPEPFVFPTSSRLPPYGNIRPSSPAPRHDTLVDGDDDLAYAEGTDGSFSFSQGVPARLPLHMIAGAEASQMALKADRCNVQMDKLERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFL4</accession>
    <name>A0ABR3ZFL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytosolic factor, phosphatidylinositol/phosphatidylcholine transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEC14</name>
        <name evidence="3" type="ORF">Sste5346_003102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="107"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="39029" checksum="BC0FCA7BB7A11FA9" modified="2025-10-08" version="1">MAADAAANGGMELDPKYDNYDYPIVSPADVSGHPGHLTAEQQAQVHQLRLMLEAQEFTKRLDTLTLLRFLRARKFDVNLALKMFVECEAWRKETGLDDLVATWEYPEKEKIFEYYPQYYHKTDRDGRPVYIESLGNIDLTAMYKITTPERMITNLAVEYERLADPRLPACSRKAGHLLETCCTIFDMKGVGISRAPQVYSYIKQASGMSQNYYPERLGRFYLLNAPWGFSTVWSIIKGWLDPVTVAKIHILGSGYQKELFQQVAPENLPKQFGGSCECEGGCGFSDMGPWREPEWYKPAAWEKKEGDASAAAAAAAAPVDPEATKTEEVKLEAPGAAAEEAAGAKETAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGA2</accession>
    <name>A0ABR3ZGA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734986" description="Integral membrane protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22079" checksum="00319CAF3274C713" modified="2025-10-08" version="1">MAYGLLLLRSTPMVLSAAAVQFDYSQYLFLRPFLDLPSDLENKDKVATDESRSPVNTLLGHFIHRQFPAGFGAILTLYPLTWVVTGANLLLSYPTSRLASLFGLSTAAGINLTPAARHFYTAGLVFSVGHMLFGPRALDLMETIGSLGEKANRPDSEKKQHNNLHLLSTWLQLHLTRTFLADVPGWLCFTAAFLLSARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGS9</accession>
    <name>A0ABR3ZGS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nuclear pore complex protein NUP96 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear pore complex protein NUP96 C-terminal" evidence="2">
        <location>
            <begin position="171"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="680" mass="75145" checksum="C4934E7FD5F3C7D3" modified="2025-10-08" version="1">MDPTDRAFHDAVRPIWSTDGACIVTEAQTDDTEPSLKRIRIYDSIGAQLTDTQYSLEGLSDHKDVVDVQVADGVPTISTRRIPEIKAFAGFCEQANRSRSAGASNLSQQLGAYEQSVWELASVLFDPIDENASTSGDQSRQRRDNLAKFWAQLVEGSSSAKSLDQAQSLEEKAFLYLASRKAPEACRALVDGKNFKLATLVSLIGTGDSFKKDMREQMDDWQQGDALSEFSVPLRSIYSLLAGNVAVCEGKKGGGVENRMSSVVLSNWFGLDWKQAFGLRLWYGISAGEGIESAVAKYVEDLEQGRVPAPRPWYTTQRDITAAWADPQRELREDLLFGLLKVAAGLARLEDVLEPENSQPSPFRYRFCWQINQALSGVESISPSAKLSTEKADALSTSYASEVVYQNDRFAIGASDGTWVHAIWVLLHLSDRNSRTHAVQDVLARHTGSLFANNGAKSNLYDNLVDDLKIPAQWVWQAAALYWRNEQNQPVLEAECLLRASAFADAHRIFVKELAPKGIVERNYSDIAEMLEKLQPHRQQIKDWTLGGEVYSRFLDLLTLQRGGTLGGSAGGNAAPRTRGRQQQQARDEAEQASAQLISVVEALASSLPAMYDNAGNALPTEVAAITEMADVVAKETMALANKGRMDLTKISRLPLTEDRRVRYSSDLAFAYYREVMSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHB4</accession>
    <name>A0ABR3ZHB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF115">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="2">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="121" mass="13044" checksum="CC0E7F1BCE021957" modified="2025-10-08" version="1">MAGKFEPKTPVNLQPPKDDPITLEELAQANGADGGKCYVAIKGLVYDVTGNKAYQPGGSYNVFAGKDASRALALSSTKPADVQSVWQDLDDKEKGVLNDWITFFSKRYNVVGKVVGATNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHJ7</accession>
    <name>A0ABR3ZHJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL46</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04661">
        <property type="entry name" value="NUDIX_MRP_L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021757">
        <property type="entry name" value="Ribosomal_mL46_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033650">
        <property type="entry name" value="Ribosomal_mL46_NUDIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11788">
        <property type="entry name" value="MRP-L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL46 N-terminal" evidence="9">
        <location>
            <begin position="56"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="38011" checksum="1F2A547F4BB6A52C" modified="2025-10-08" version="1">MASSRRGGQAISALFKAILPLQRRTYSAEAAAAASSSPQDSASSSSTSPPATEPDYRIRAGLLLSRPPLLVRDPTPFESAFYLYQKRLNERLSSSFRRKVYFKPDTTLDLDWALQLRERKGTAARDIGFYQGGKGANGYGAATAWNDEVTLDDPDAKTLTDPNLLRERIISDADLRVSEDGERLPEADRIHVERPQPRKTKADETNDTQRLDRKMDRTLYLVVKAADGTWSFPTADVRTDENLHETATRALEWAAGIDMNTWVVGRVPVAHIVRDLTPTEKEAYNSEKTFLIKGRIMAGQANLKDNTLGVSAFQWLTKDELAVHLPKHYYASVKNAMPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI54</accession>
    <name>A0ABR3ZI54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045477734" evidence="2">
        <location>
            <begin position="19"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="406" mass="39316" checksum="19522D58DEC79C92" modified="2025-10-08" version="1">MSAIRSVFAATLVALAHGHMIMNTPQPYSSPAVVNAPLNADGSNFPCQLTAGGSLSAGSASNSYALGSEQELKFTGQAVHGGGSCQVSITYDSNPSASSTWKVIRSIEGGCPAQGQTGNMGDDASAADPYTYNFTVPDNIPTGSVTLAWTWFNKIGNREMYMNCAPVTLTGTSGSQSNFDSLPDMFVANVGNGCGTVDSTDLLFPNPGGDVVSMNGATSAFSTPTGTGCQAAGAAPSAGSGSSGSGTTAAAAGTTSAAAAGGALTSTPGGVFITVGTSAAAGGAATTTPVAVAPSGASTTTTSATSTTTVAAAGAAGTSSAAAPAATGSSSTTSSTSTGSAETAGSACSPDGTWNCLGDSYQQCASGVWSVVQPLAAGTTCTGGQSAAINIVAGRKSRRVALRFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ13</accession>
    <name>A0ABR3ZJ13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="27121" checksum="F1E6D9446B450553" modified="2025-10-08" version="1">MSTNLQGKAIAVTGAGGGMGVETCKMLAARGAKVSMADLAGPAEDTMHRVAEEITVAGGTVLVTAVDVTKQDQVDVWIKTTVTAFGQPLDGACNLAGILPRHFNTAKETAEDMDDDEWDRVLAVNLTGTMYCMRAQLRNMADGGSIVNASSIAGLMGTPKNTSYGAAKFGVVGLTKCAALDAGRSRNIRVNALAPGTIRTAMYEEVVKGRGGLELEPTQFIQRDGRPDEVAALCCWLLCDESSYITGQVHNIDGGYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJH2</accession>
    <name>A0ABR3ZJH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF5">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE CYTOCHROME DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047365011" description="DOMON domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="2">
        <location>
            <begin position="78"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="23206" checksum="FEF704C2873A4CF7" modified="2025-10-08" version="1">MRFWGLASACVAALAGSTAAAGTTTYHDPETGFVFAEYAIQYKIGHTLVFRIAVPTGVQSLTAYDAVLQVVAPVDAGWVGFAWGGRMIGDPLAVGWSSGNSVVLSSRRASDHTNMPATWTGAQYTLLKTGTHVNYTHWQYTAKCTGCTYYTNSVGSKNWIYSTGTNHLAFAYSSSRPAQPSSSGSTIQIHDVTNNWDHDFSVGQNANFADLVTRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL59</accession>
    <name>A0ABR3ZL59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MINDY deubiquitinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="2">
        <location>
            <begin position="465"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="781"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="879"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="936"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="966"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1100" mass="117904" checksum="E4A66E3587F054E1" modified="2025-10-08" version="1">MVVRKPLPQSCDGASSPVTPTGDSVPDILRPGRKPHPNSPYSPAPPSPYSNFQTEEQSAWTQPPPPVMPQGMANQSYNPQQPNTQESQQPQVSPVPTAIPTILLQSATGSSTASSFSDTNPFKRKVLASPSGTPVQSPAVAAPPSPSAPPPRPPSSQPLPPTERLSQLSMDDQAGNPWQPTMTDSRRGSQAPIPVIPENEAVGAGENAWASQNASQYPSRRPSPIMSRANVRDSNLISFPPDDDADIAGWDEVASPVAAAGASATSAPPPRPPFTPLDGKETGSETNGAFEDRNAWDDLGVSNSQPQALPTNIVTEPAGEGWNLVDNEPAPGQLSRQSTWENFTDDDEDEDPDQASANKPRPPIKKKKLKGKSTNPAVPVPVVDTSAPLISIDSPPPTSKPDEPVQDAPAEQYAPPAGPPPSGQQPATQEAEPPAPQLPPRSMLDIDGVAPPRQPPRPSESGKAETYAVKNIRWYDHRAAENPRVSPILVQNANGPCPLVALVNALTLTTPADVNTALVETLRSREQVSLSFLLDAVFDELMSSRRSSSESNLPDVDELYKFLKGLHTGMNVNPRFIPTPEVITAFRRTSLTHLHPTERDDMIPGTFEDTREMQLYATFSIPLIHGWLPQKGDGAYEALSRQAASYEDVQNLLFREEELEEKLSGPDGDGLNEEEQQLFQDILEIKTFLHVSATQLTPFGLDVVAKAMRPGSFAILFRNDHFSTLYRHPQTMQLLSLVTDAGYASHDEVIWETLVDVNGEHAEFYSGDFRLVGGNSLQQTSSAGAGSSRSNGSGGGGRSSNDQSGWTTVRGRHQNQNEPPAAEQSQPLSTEELSRHEQEDRDLALALQLQEEEEEQQRADEARRNSRLSEQFIEQNARPANQSGSSTSNSRRPSNAAGGGRYNSSQQIPVSPRRSSANYSSTSLLDTTNGNHRRTSSSSASGSALGSTMSNGQRVGQYSNNLNNGRTPSRSPSSQQQVIRPLLPPVSNTRVNTRPAVSRPADPEDGDEAPPSYEQAAKLAPYHPPPGAPGSESAAPGSSSAAGSSSGGGASRTTPSPRPLVGYATNSGSSAGRQNFTPGSYNAYQRQEAINRGDRDCTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL80</accession>
    <name>A0ABR3ZL80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_001885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959:SF1">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="VOC" evidence="11">
        <location>
            <begin position="51"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="11">
        <location>
            <begin position="264"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="52153" checksum="6DE8CB7F81CD85B8" modified="2025-10-08" version="1">MSPSAISDSPRNSVSDPHNAHRNVFGGATTKNGSAIDAAVSAATGTPTFHGYDHVTWWVGNAKQAANYYSTLFGLPTFAYRGLETGSRYFASYAVGHHRGGGVADSAIEDDQDNVCFVFTSPIRSYRHLPEDEPISDAERALLKEMHDHLERHGDAVKDVCFTVDSVEGVYQQATAEDGLSKDAKVVGVQPPAQIHDKLYGGSVTTAMIRTYGDTTHTLLNRGDYKGPFLPGFRAMAPPKAAPAGTATFKPVVMAPAPPVGLQRIDHCVGNQDWDEMEAACEFYEQRLGFHRFWSVDDKQICTEFSALKSIVMSSGGNADTVKMPINEPAAGKKRSQIEEYIVFNSGAGIQHIALRTPDIIQAVSSLRARGVQFIDVPPTYYEALRERLAASANGTGAKLEWHISEEQLAIVQQLNILIDYDEGGYLLQLFTKPLMDRPTVFIEIIERNNFEGFGAGNFKSLFEAIEREQAERGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMA9</accession>
    <name>A0ABR3ZMA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Haloacid dehalogenase-like hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF1">
        <property type="entry name" value="COLD TOLERANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37633" checksum="A2F3372E391949C4" modified="2025-10-08" version="1">MHVILDFDGTITVHDTIDHLAAFAVEFQEKRKASSSNSDVDWDAQWKEIVDNYLADHRDHKAAYSPAEDARTSLDHELEFIRSLHGVDCRSIKRLRDTGLFANMTPVPEQRLFEAGQKAADEGAAKKGGDDKDSVRVRLGFSDFLRETSTTRKWPVSIVSVNWSDAWIQGVLSREDNGGPGTNEGPAIRVFANKVTASGAIIPNFRRKDATTAVDEEHEHDDNVPFTSSSDKVEALECAVAEAEAASASGIDDAVVYMGDSTTDLECLVLAGSKRAGGGGIAMANGDGPATSKLIQTLVRLGYEVPHVSESKRFQRPRSEDEGDEPRLAWARDYEEILASKVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNE9</accession>
    <name>A0ABR3ZNE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">KRR1</name>
        <name evidence="14" type="ORF">Sste5346_001199</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="123"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="273"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="327" mass="37963" checksum="EFF9A63560B75852" modified="2025-10-08" version="1">MPSTQNKEKPWDTDDIDKWKEDAFKPEDNKSGSFLEESSFAVLFPKYREVYLREAWAGITRALQKHGIACELDLVTGTMTVKTTRRTYDPAAILNARDLIRLLSRSVPAPQALRILEDGVAADIIKIRSLVRNKERFVKRRQRILGPHGSTIKALEILTETYILVQGGTVSVMGPYKGLKEVRRVIEDCMNNIHPIYMIKELMIKRELAKDPALANESWDRFLPNFKKRVLSKRRVPHNVTDKAKKTYTAFPPAPEKSKVDLQIETGEYFLSKQAKQRAAETERQEQARERKEEKKRERERDFVPPEEGDEKRKKKKRKTKEVEAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ44</accession>
    <name>A0ABR3ZQ44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hsp70 ATPase ssc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SSC1</name>
        <name evidence="5" type="ORF">Sste5346_000982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="559"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="645"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="646"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="673" mass="73039" checksum="DF72F285E8D5017B" modified="2025-10-08" version="1">MLASRFSRALPRASSVAMRPAAMRPSAFRPAFARFESTGTEEKVKGSVIGIDLGTTNSAVAIMEGKVPKIIENSEGARTTPSVVAFSEDGEKLVGVAAKRQAVVNPENTLFATKRLIGRKFKDAEVQRDLKEVPYKIVQHSNGDAWVAARGKNYSPSQIGGFVLGKMKETAEAYLSKPIKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVVNEPTAAALAYGLEKEADRVIAVYDLGGGTFDISVLEIQSGVFEVKSTNGDTHLGGEDFDITLVRHLVDQFKKDSGLDLSGDRMAIQRIREAAEKAKIELSSSQQTDINLPFITADASGPKHINTKLTRAQLEKMMDPLITRTIEPVRKALKDANLQAKEIQEVILVGGMTRMPKVAESVKGIFGRDPAKSVNPDEAVAIGAAIQGAVLSGEVTDLLLLDVTPLSLGIETLGGVFTRLINRNTTIPTKKSQVFSTAADFQTAVEIKVYQGERELVKDNKLLGNFQLVGIPPAHRGVPQIEVTFDIDADSIVHVHAKDKSTNKDQSITIASGSGLSDSEIQRMVDESEQYAEQDKTRKDAIEASNRADSILTDTEKALTDHADKLDKTESDALREKITELREYISKSQAGEGDATAEEIKAKVDELQNASLNLLDKVHRARSEDAPAEEQKPEGEKKDEPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQC0</accession>
    <name>A0ABR3ZQC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051114">
        <property type="entry name" value="Mito_RNA_Proc_CCM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057585">
        <property type="entry name" value="TPR_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934:SF6">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24603">
        <property type="entry name" value="TPR_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="409"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat" evidence="5">
        <location>
            <begin position="527"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="907"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="942"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="4">
        <location>
            <begin position="1036"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1221" mass="133254" checksum="4331F83AE8EAD4CA" modified="2025-10-08" version="1">MPTIYSSLYQTFIRQGFAKSFTHGYAQSVVAATHPHVLNPQNRPSFARRNSNRFGRIQALQLQSAFHTQTSGSDHKQLSVNHGGLDAYFEHLQDLQAQDEADKEWVQFQFQNRIEWKPTAASVLAEETQADVEAAAAEEANAEVVAAPAEEGELLASEQVEVENVTAAASAASIEAVAVEENAADRHFAAEEAALAHIDAALEKEIEARKHLEALEDGKVASASLAAAGEAPVSRSVPVSRSRSPVRAASPVVDKQSQTYADHLTTLSESGRYAEIPAVFEAMLVAGVQPIASAYNALLMAAIHLPIDRMEVISKALDVYTDMIRRKVLPDSDTFNILVGLLASRSLELAAKKTSLEEKRLRYGGMDEPGKFMFASHELEHAIAAEEDRLDYAIKLFENSVAVQKAAYSSETYHQLISACAQSGRLSDMLQLFGHMETSKIAPFAATFPAMITAFANAGDLISAVECYEEYRNLAIANDAGEPTLLDRLDTQVYAAVINAYITCDKLPGAMKFFQKINEQYGVRAADMKDALVNLGFVQGFTSRGNYATALEWAQNVDKTIQAQALGEIATVAADNGHKNLAVAAFDALTSAFPSALSSMTDPTTALLALHVRSGDVATASKYWHILRNPLVEVSSSFIEPTAMYAVAMIGSGQVAEALTESEIMFDRIRQSGEARTHAAIVDEIEEGVAFISRFMQARGVTDPREDASSVASFVPPASSFVSSPFPSTPTASSFNETDNFDPYAHNTDFKGSSLISDDLEGAHGRKGPKLNEALNRFRNMRRAGRHPRYITYAKLISTASRENKMDLCHNILAMARTDVPLLPQYAVVRYGWSSILDAMIGASLSVGNRTLAEQYHQELLSFGSAPSANTFGLYITTLKESTKTFDEASEAVKIFHRAKAEGVEPSSFLYNALIGKLGKARRIDDCLFYFAEMRALSIKPTSVTYGTIVNALCRVSDDKFAEELFDEMEAMPNYKARPAPYNSMMQFFLTTKRDKAKVLAYYERMLARGIAPTSHTYKLLVDTHATLEPVNMTAAEAVLDRIRAGGQTPEAVHYASLIHARGCNMHDMEGARRIFDSVMKDKSISANACLFQALFEAMVANHQVADTEPILAMMRERRIDLTPYIANTLIHGWAAEKDISKAISIYSSVGRERREPSTYEAMTRAFLAVEERDKAQGVVSEMLHRGYPSAVVNKVLELLGGGAGHAEEAAAGAVAAPVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQL2</accession>
    <name>A0ABR3ZQL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="368" mass="40273" checksum="3B26732FBF2D34DF" modified="2025-10-08" version="1">MEEKAAIWDQSATTATMATPMLAMAVDDPELHYPFYHQRGRRRRRSPPPVPLSLTMTASQQMVHRPYHPPPRTRHNNPRPRQQTPSGSSGTFRGRRRHRSPSIGAASAMAAAAVAAVRKASSQSSRPHTRSSSVASSMQHVSRPSSPHEWWGTATTTPSATSNSGSWLCRSVSRSRGRQIRRGGAAGSSAAAAGRAVESPSPRRKMAYRRPMDMDHSAMMAHYHHHLLAPTLHKPYTKPVTRRSHCPSRSGSADGYRDDTSGSPTPSPVTADPIALAARRRRRRQRTQSRPRPRRMMSGDSVTGVGSSGLYELPGYYTFDNDNSMAHGDSIDDSGDTATASSRLQFQMLLEDSSDTTSDGDAMDMEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQW5</accession>
    <name>A0ABR3ZQW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Tricalbin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">TCB2</name>
        <name evidence="15" type="ORF">Sste5346_000362</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2A_Tricalbin-like"/>
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        <property type="entry name" value="C2B_Tricalbin-like"/>
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        <property type="entry name" value="C2C_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2D_Tricalbin-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SMP_TCB"/>
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        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="5"/>
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        <property type="entry name" value="C2_dom"/>
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        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="C2A_Tricalbin"/>
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        <property type="entry name" value="C2C_Tricalbin"/>
    </dbReference>
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        <property type="entry name" value="C2D_Tricalbin"/>
    </dbReference>
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        <property type="entry name" value="SMP_LBD"/>
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        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
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        <property type="entry name" value="Tricalbin"/>
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        <property type="entry name" value="Tricalbin_domain"/>
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        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="TRICALBIN-1-RELATED"/>
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        <property type="match status" value="5"/>
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        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="2"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
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        <property type="match status" value="5"/>
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    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
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    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="236"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="436"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="580"/>
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        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="721"/>
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        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="1084"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="1351"/>
            <end position="1465"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="875"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1274"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1318"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1475"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="901"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="935"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1475"/>
            <end position="1488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="1512" mass="164993" checksum="51702D9C95168606" modified="2025-10-08" version="1">MATLNQSLPEVKQQVVQEAANDPNSPITSADAQAHMVQESKKAGVPAFSFNPDASPEEKKAQVRAAIPDNFHNPKRVKGIAIATDIDDGSAPAYDLPSPTKAGAIAVPKTEDGKPGENGTVADGETGMGPDTTGWAPRFGWPTESIREGTSLLEHSTWLEGHLPDKLYGDWYHNAGIIIFASLTSWFVAVLGGGLGWVFIVIATCGTYYRTSIRRVRRNFRDDLNRELSQKRLETDSESLEWMNSFLVKFWPIYQPVLAQTIINSVDQVLSGATPAFLDSLKLRTFTLGSKPPRMEHVKTYPKAEDDIVMMDWKFSFAPNDIADLTTLQVKNKINPKVVLEIRVGKAMISKGLDVIVEDMAFSGLMRLKIKLQIPFPHVEKIEMCFLEKPTIDYVCKPLGGETFGFDINFIPGLETFILEQIHGNLAPMMYAPNVFPIEVAKMLSGSPVDQAIGIVAVTLHGAQGLKNSDKFAGSVDPYTVITLNRRSPLAQTKIIRDTNTPRWNETHYIIVTSFNDSLDLIVYDFNDFRKDKELGVASFALENVEEVNEAENETLEVVSDGKAHGQVSCDIRFFPVLSEKKLPDGTVEPAPPSNTGILRFTVEQAKDLDGTKSLVGMLNPYSVLLLNGKEIHTTKKLKRTNNPIWDNGSKEILITDRAKAKLGVVVKDERDIAGDQIIGNYQIKLDDMLEFMEKGQDWYNLAGAKTGRVKMQAQWKPVALSGIIAGTGGYQKPIGVMRVHFMKAAGLRNFETVGKSDPYARVLLSGIEKARTVTFKNNLNPEWDEVLYVPVHSTRERLQLEVMDAETMGRDRSLGLLEIFAGDFIFEGEDGSYLVNDKKALREEGLKLHGKGMAKGTLSYTVSFFPCLNVADPEEEELEREKEAAKEQNGAAASANGSVPTSPTSPTSPTSPTSPTSSKTPASPTVPNAVPGSPTMSQPESDVLSTKTEGPPKIHLTPEELLKYESGLVVFKLMEAEMPRPDTQLEIFVDDMAFASYVSSSARTRSLTFDEMGDCFIRELDFSRLTLKIRDRGDDKKDDEKDRTLGRLTGNTLDTLKQCLNNPTTLKLKDEEGRISSVRVSLKYIPVQMELDPRESINNMGNLRVDVLDAESLPAADSNGKSDPYCKFDLNGVEVFKSKTQKKTLNPTWNEFFEIPVPSRIGAAFNLKVYDYDFADKPDFLGGAPIRLDQLEPFKASEIRVPLDGKSGTVRLRLLFRPDYVTRQRQGTSTFAAPTRIVTGVAGAPIKGGAAVVGVVGHGVGKGASFLRRGFRGSKKDEEITTSSSHGSVADLAAPGTAITTNGESAVPNVMVKRASGLAEPPSQNGEPALDAPPGPALSASRSLGHNRTASGAASIYSVVPGSPGSGAAVFTIVSASGFPPSSDVYVTLNQVGGKSKTIGKTKHHKAQGGVVQFDETFKSTCTADTQFQVQVREQHRFGSDDILGESLYVVDESGTNAEKEIKVGDGSVVVKSTFTPHESTGSTDSPKSFRRSFLSKREARPPSSREGTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR17</accession>
    <name>A0ABR3ZR17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Developmental regulator flbA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
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    </dbReference>
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        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
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        <property type="entry name" value="RGS_sf"/>
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        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEP"/>
        <property type="match status" value="2"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0734">Signal transduction inhibitor</keyword>
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        <location>
            <begin position="482"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
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            <begin position="604"/>
            <end position="750"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
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            <end position="91"/>
        </location>
    </feature>
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        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
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            <begin position="148"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
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        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="576"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="776" mass="85285" checksum="E92F7121F3B60DC6" modified="2025-10-08" version="1">MADVSHPSRSEPLSTDNTTNNTLTSSSTTTTTTTPAINKTTPSNFASEREARRDLTSKFRFSTSTNFVIPQTAPDNNGNNNGPDNDTASLAANPNVSVTTTASGYRAHHSSTPSIISVQPGSSSTKSPRSGSLLAFATAAIDRTQTALSTAEQKIRPRQSVGRLSVGADTPAVPTFPTYYSLDRSPTNASASSSSTPLSSQNNDHKSDALPPPSILSATSSDDASQSTHLPGNASDQPQRKLSLSYAKPYDQADPTLPLPIRLPRTDNKMHQTSSRLLRMTDDDRPFTKDFKDLFATLIVSLLPLSAHRVRLTKVEHTFLSEDAINNLGSLKFSQSNRMPDPKDPSRIVTTTTTTTFSMAKDMARSICQRFLEARFIESADGKYQQVYTMKGSVWQLTPKGISILDRFCSRNGIQQKQVGELIGHSTSQLVILERDSQTDKLVCDRGTIEVIFRRFIGVNGLNVKQSVNAADADSLSDYRDGMTGVKVASERKVSGKTYKDTFTGKAAVDWLMDCCTTVDRREASEIASLFAEYGLIEAIQHDRVFQSQVPSSHLFQPTKNAIFQLTAKGRDLFNGTSSRGRSSESDGGAALRPGIARDSNTQRLDKILNDAALRLLFRENLRETHCEENLSFYLDVDDFVRNCRQSIRLAQKNPGTTTMDGIKEIMAQAYGIYNAFLAPGSPCELNIDHQLRNNLATRMTKAVGQDGAMIDTLHEVTTLFEDAQNAVFKLMASDSVPKFLRHPKYEHTLRNYDFDAIVVGANRVPERSQSRSNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR56</accession>
    <name>A0ABR3ZR56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CDC60</name>
        <name evidence="14" type="ORF">Sste5346_001180</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07959">
        <property type="entry name" value="Anticodon_Ia_Leu_AEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="34"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="206"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="830"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="13">
        <location>
            <begin position="980"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1116" mass="125201" checksum="A7DF58F220D03D81" modified="2025-10-08" version="1">MDGQDAKPVGSERTLKLENTDKRDTLIADEIRFQDEWSKAKYFEQDAPLPSEPEQDKLFTTMAYPYMNGSLHAGHCFTFSKVEFMTGFARMEGRRALLPQGYHCTGMPIKAAADKLKREVEMFGKYFENNPDVQEEQGLAIRPAPGAEAPAAAVPTEAKAKTDMSKFSSSKSKAVTKSGKAKYQYQIMVSLGFDLKEIHKFTDPEHWLQVFPERCETDLRRMGARVDWRRSFVTTPANLYYDAFVRWQITRLRELGKIKFGKRYTVYSPKDGQPCLDHDRSSGEGITVQEYVALKMKALEWSETAKQVIGDKLPAGSDVYFIPATLRPETMYGQICCFVGPSVAYGIFKCPVAGKEGKFEYYLCTERAARNMAYQNVLPWGEFESVVQLQGSDLVGTLVNAPLSVYEKVYILPMQTLKPTKGTGVVTCVPSDSPDDYATVTDLLRKPEYYNIKKEWLEKDILPVIKTPSSDLIAKYLVEKLKINSPKDTKLLEQAKEQAYKEGFYQGTMLVGEHKGTPVQDAKPLIRKQLLDAGLAFNYAEPDGEVISRSADVCVAAYLDQWYLNYGTTENGGDGEWCDQVLGALEDGTVNCFYPEAKHAFEQTLNWLGHWACSRSYGLGTKLPWDVSQLVESLSDSTVYMAYYTVCVYLHGDIFGKTPGKASKPITPQQMTNEVWDYVFCRTDSVESDIPKEDLEGMRREFQYFYPLDARISGKDLINNHLTFCLYHHAALFPKKYWPRGMRVNGHLLVNGQKMSKSTGNFLTLRESTEKFGADATRVALADAGDGIEDANFEESVANATILRLYELRKWAQETVADTTLRTGELGLFDKMFENEMNTLVMETKKHYQGTFFKLALKSGFYDFTASRDWYRDITKASGEGMHRDLVKRYVELQSLLLTPIAPHVSEYMWRDVLKHEDSVQTALYPTVPAPNPSLTAARNYIRNTTSNITAAEGLQTKKLAKGKAIAFDPKKAKKLTIFVADAFPEWQDKCIEVVKQVLESTGSVDVKGVTGKLDKAELKKSMPFIQALKKRIDSGEDAAAVFDRKLAFDELATLETMILGLKQTVNKLETIVVVSVKPGATSGVVYKGDGQTLDPLPQAAAGATPGNPSFLFENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRI2</accession>
    <name>A0ABR3ZRI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="39348" checksum="23F43B5EFD69D376" modified="2025-10-08" version="1">MSSTIAAGEVPASMPGTTNVRATPKITRPRRTVFPVIREDFVSDTANLSLDGCPRTPSPWSSPGSDFELDTPFIGEESYRTEYETTVNMGLVALLCAIRLHCPELVAGHWLPDPKLFELCDSSGAILWAHVDGYLSKKGHGNTAFGIIEVKPYTRHAKRVKIEQQKAAQMAAWISQTPGELKGNLKGAPGSNIRREIFITVAEYGTEYEEYISKYSKNDPTTADYSPDSTSNSISSTSNNTSAMYGTPTPAPRICNQAGSQVGHASGNSGSSGSRAPPLNLHNPKTGRALPKSGQNVAYGGKQATGPGSSKAFPSMPKKYPNRGFLKMTTYSPASLTNPSEMVRLCKLIAALSMQVLRDLVPPSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRL1</accession>
    <name>A0ABR3ZRL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">syj1</name>
        <name evidence="7" type="ORF">Sste5346_000606</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="6">
        <location>
            <begin position="185"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1018"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1081"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1103"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1138"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1157"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1184"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1206"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1230"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1263"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1273"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1328"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1348"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1359" mass="148558" checksum="89C56792006971CA" modified="2025-10-08" version="1">MDYVGSTVSWNGQVPDPDTSSRLLIRDYPHRAIAIVSQTHALIFRHSAAGSESQNGSSANGGNGGGGGSAISKCMVEFSPITKGMLSDYRPLTPRPVYGTLGLIAVNQDVFLSVITQALRVATLRPGETAEMIQQVQFFCLNTNEYDDVLSAASDPWDPDGDSASVYSQGLSRRDVPVEHPCQELMKLLGNRSFYYSTDFDMTNRLQDRSADASSFDIDNFDESFLWNSFMIQPLVQFRARLQPHERETLDSSRILTSAVRGFCLTVTIPQSVAPLRNTQSGMPSYLTVISRLSCRRAGTRFNSRGIDDDGNVANFVETETIYWSPSGVVFSYVQVRGSVPVFWEQSPGLIPGHQKIIVTRSPDGAQPAFDKHFEDLETSYGAVHVINLLSEAKPGEAELTQCYRYGLQHTPLAQKSSDRNSSSDHALIRATEYDFHAETKGPTGYEAAQEIRHYIENSANGFAYYLAMEADDARSSGNSGRKQSSASAHRRFVVVLQQEGVFRTNCLDCLDRTNLIQTIISQMAVETFLDHRSERAGSDFWVRHSNLWADNGDALSKIYAGTGALKSSFTRHGKMSLAGAIADARKSATRLYINNFADKGRQNTIDMLLGRLYGQAPVVLFDPISDYVTLELNKRAATFSSSEVIKIWVGTFNLNGRLDGLHEDLSPWLFPTQVKSADQLPEIVAIGFQEIVELSPQQIMNSDPTRKQQWEVVVRNTLNKHAAAAGGEQYVLLRSGQLVGAALCIFVKSSSLAKIKNVEGSVKKTGMSGMAGNKGAVGIRLDYANTPICFVTAHLAAGFANYEERNRDYLTIHHGLRFQRNRGIDDHDAVMWFGDFNYRVGLGRDRALDLVRTRNLEALYENDQLNLQMVAGLAFPYYSEARITFMPTYKFDVGRDDYDSSEKQRIPAWTDRILRKGQHLRQTEYNSAPLRFSDHRPVYAHFQCTVNIVDEAMRDKISRELYERRKGEVGDVTANTTVEDTDDEDLIGYDAIEPGLPAASSDRQKWWLDNGRMAQARIQPPTPANPSTHTTVLNPKRPANPFSPTDEPDWVAVPRAESRLSSFSSLSTSPYEHINHSTVLSSSANSQNNGSAAASRKGGQPMAQSLSSQFYRQDATATPPPPPPPRRQGAGNTENDAVSVASKKSASTASFASTFPGPPPPPNSRVPPTISGVTKALDELRASSSSSPSSFSNASDRHGPPVLPRQTSTKVNTTFQPPPTHAISPRPVSAASSTSASGTNISAKGKPVPPVAKKPAHLASVPSTTPSPTSSRVGSASHNLGDGTSSGTPPPKPPRRRTDLAASGYSDTPPKLPARTSTVASHGRPIPSSTKARSSNIDLLGDDDSGNELSRYQPLQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRP7</accession>
    <name>A0ABR3ZRP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 6">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DTD1</name>
        <name evidence="7" type="ORF">Sste5346_000844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="164" mass="17616" checksum="7229DC2D70FEA5CE" modified="2025-10-08" version="1">MKAILQRVLSASVTVEKEVVSSIGKGVLVFAAVAPGDTEKDVDSLAAKVVNMRLWDDDEGGKWKKNVQDIGGEVLCVSQFTLLASTRKGNKPSFHGALGGDEAQRLYNYFVQKVRENFAADRVKDGVFRAMMEVALVNDGPVTLELTLPAKANASKDSAKDSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRQ1</accession>
    <name>A0ABR3ZRQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED11</name>
        <name evidence="5" type="ORF">Sste5346_000670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019404">
        <property type="entry name" value="Mediator_Med11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22890">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10280">
        <property type="entry name" value="Med11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="177" mass="19337" checksum="A644848E7AD0BA34" modified="2025-10-08" version="1">MDDSTGINTGSQLAVIDVHEPFTLPERFQQLAEIDNDIIKLLTLANDIIQPLSTPDGASGPGAASTADAHTETQVAAFKEAMDSFLTTLHSVDVRLKRQIWGLEEAGLISLKESKPFEVSLEPNGVGDIGSLDVGWLNSRSNKVDRDMETELWSTMRATVERLGQNDSDQRETGIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRS8</accession>
    <name>A0ABR3ZRS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001484</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF77">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="428"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="60342" checksum="5C98DB1C338FD4A7" modified="2025-10-08" version="1">MALFAAAYAPAVALVLVATAILYYVLSAITAARRLRAFPGPRIASFSYYWMATTAYSGRMWEIYYKQATLQYGDVVRIGPGELLTSDPAIIRRLSATRTPQYRRSDWYNPNRLDPYEHSMFSLRDDVAHDRLKGRTAAAYAGRENPALEAEVDAVLKQLVDVIRTRYVATRKPLDLAVLAQYFTLDSITKVAFGQAFGFLEREEDVHAYLQSILDIAPVMQMSSEVPFLNRIVTSPLVLSLAGPKVTDKAGIGRMMGVARNIVAERFVPDAKDRRDMLGAFVRNGLSQRECETEALFQIIAGSDTTATAIRMTLLYIMTTPRVHARLREEVDHECADLGDDEIVPNSRAETLPYLQAVVLEGLRMHPPFVGLPFKEVPPQGDTLPDGRFVPGGTRIAPSIWALTRRKDVFGEDVDVFRPERWLSNEPVHSEANSAAIGNGNGAANGNDKTNGTASERSEDQERIANMRRTVDLIFGYGRWACAGKTLAFLELNKTLVEMMRRFELQLVYPLRPVSQINHNLFLQRDMWMQATERTRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS07</accession>
    <name>A0ABR3ZS07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho GTPase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BEM3</name>
        <name evidence="5" type="ORF">Sste5346_000336</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13277">
        <property type="entry name" value="PH_Bem3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="729"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="1050"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="778"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="853"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="931"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1240"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1385"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="254"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="531"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="778"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="875"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="888"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="898"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1279"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1310"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1339"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1433"/>
            <end position="1449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1449" mass="156554" checksum="5C4C694D134A6BA2" modified="2025-10-08" version="1">MAGPSTAPLAEANGAPRNASIDSGVSALSNSSTARKNSTDSVTTHDIPSIIKAAGSAEAVIEHLLKEKQAQSQQNAQLWRLVDKQRAMILGLNKDLERALKDKEKYRRKVKEFLPDHGRPPVPLIPESTASQQQQKGMPGSSAQNGSTSSLPALSISTMNRVASEDVPSSPVSVKDSPVHSPLQSPVDMSLAPYPITPPADQPSIAAASAVGGLLDPVESMPRPQDHALDNFDHEAEDRAADSARHTTNAANDIPISFSLPPSRSLPSKPPQVPPPQIPSASSEDGGASQFPPPPAPPPRKPPPAPLLLRDPRPSPTIPIDDEVLESDSDYDSLLEVTEIAEKEKRGRRRTREEDDREREILAIQEAEIRSLSKKSKKSNSAHGTPKSAGQPTAAPDTVPPSLMLSQATLQPPNSLDGMLNSDGADINNNVITVQRSLAAPLLSPGLPSSPRPMTGNAMPRSPLHSPPLSPRMGGNFGSAGAAPLSPRPPRQPIPLPPNTPLQTPSPAPGEPLMLSSPKPLNIIKKSSDTASSNAPSSPSVKSVKSVNSRETPTERTRIFKGFVTEEFPDLLLPPNALPSIDIKVASSRMKPSRASLISLTQLEEDPVFTLAIFSRADGGELWRVEKDSASLAKLDQRLKQCPAFTARTPDRSLFSGHAPAKLDARRQALNYYLDELLNTQLDNPTAMELCRYLSTNTLPPNADETGSTSAEVRKEAQANKAKINFGDRPVKTGYLTKRGKNFGGWKARFFVLDGPHLKYYETPGGAHLGTIKLQNAQIGKQSQHNETSSPARGGANNNASDDFDNQYRHAFLILEPKKKDPSALTKHVLCAESDHERDLWVDSLLRWIDYRDEGDDDDTPSISGVPGTLDPDRPSSSNDTRPNGSNTKKRQNKKQQQKPQISSPQLQTQPQQSFGKDGLIGVSYEATQQGEIPHGVPGNRQRRNSQDSDMPQTMSSQSPYAISAPRDPQVISDSSAWGGRAAMLGTGLAPPSVDEKKARKRSFFGFGAKTRTSSDGPSDSLFGDSNSGGPAGSSNGGGGGGPNRQVFGAPLAEAARYNSPVDVNVPLPAVVYRCIQYLEARNAVYEEGIFRLSGSNVLIKQLRERFNNESDVNLLTDTTYHDIHAVASLLKMYLRELPTTILTRDLHMQFLSVTEMSNQEEKLSALAELATHLPQANATLLKYLVAFLIRIINNSDRNKMTVRNVGIVFSPTLNIPAPVFALLLQNYEAIFGIEPEEYELPSSVSDDPQNRRPSLSSMSTGATIDPLPQRPSTSHAGESPHRQRLLDAVKNGGNGGRNTQTPPPVLMSSAGSQMQSRSGSTPTPPPMQPPPSFPLPKPLQQQQQRMTTYEPQYLSQQQGNSQVSLRPAYESGFVLPAGYDPMQLPASNPVRNNPGYDRPLYEGSSNGGLAAYERNTRRESAILPSSPAMNLNNNQQQGGRRPGPGNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH2</accession>
    <name>A0ABR3ZSH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAR-17a/AIG1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006838">
        <property type="entry name" value="ADTRP_AIG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04750">
        <property type="entry name" value="Far-17a_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="30646" checksum="6A580DC39FF480FE" modified="2025-10-08" version="1">MVRSPFRSNGEPWDPSHRFVTSWLLRPAVLAFLRGLFGIYILVTLIVVIIYDCRNLDLGGCAAAGDTFSYFTVLTYWGLAFYFIVAAIHTATYARTGSALLDRFPRFLQQAHGLFYSTITVYPFIVTAVYWGKLYAGPWFPLRFDAWRNVSQHAMNSGFALFEIVFARTAPQPWVHVAGLIVLLALYLGLAYITRATKGFYVYSFLDPAQKGGSGMIAAYVFGIAVGCLVVFAIVQGLIWVRRWATETKGGMTGKFARADRLAVDIEMVRPNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSL7</accession>
    <name>A0ABR3ZSL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="68"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="233" mass="25868" checksum="F158673953538992" modified="2025-10-08" version="1">MSDVYRVQAKEAKEQDLDLTKLCSKVSRFLATIESALSNASSKASTSDTIARQPQNAIDRVVYGGNLIEKSLVKDAYRVLCEGTPILAEEGTDNIETPWETYAGKYRTVHVGAGSTMFTPPQFVERQMRELIHELNTELEEALAHGTLDPFAFAVKYSMKFVQIHPFQDGNGHFAGIVVPIEETKEDRGESIRIKRTASEDAADHGEYATFVLAKSESRLRAIKKKLAVSAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSR5</accession>
    <name>A0ABR3ZSR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Signal recognition particle subunit SRP68</fullName>
            <shortName evidence="10">SRP68</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SRP68</name>
        <name evidence="12" type="ORF">Sste5346_000981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the SRP68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15481">
        <property type="entry name" value="SRP68-RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.40">
        <property type="entry name" value="Signal recognition particle, SRP68 subunit, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026258">
        <property type="entry name" value="SRP68"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034652">
        <property type="entry name" value="SRP68-RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038253">
        <property type="entry name" value="SRP68_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16969">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038995">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="631"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="660" mass="70343" checksum="750659178ADBDFAD" modified="2025-10-08" version="1">MDITQFVVSSRDKALLYGDYSTYRTQLAHRLLNIRKKLRVATRHRGKYNHKANNIKPEQVAQDVSYARLQLLTAERAFAQAMAMKAAHASNKKGITGHTRSHIVSRLDKAAKYAADMSDLLQEDASGASDVDRLEAQAYAAMLRGAAAFEKQAWELCLANYAAVWAIYSALSSASATRADIFRDLLTETIEPSLRYAAYQLKMPRSKPIPIIAREALSSAKSVAATPDTGALVASVNKIDPSILQPKTAATADGSESLESAAPGTVGGVVASTRTLTWRSREVKIEDATIASAWAALDLAKARLEAQLVAGGARLAPKDKAAAYDDVLTVSQDAVDATKAAIDDLRNEGIPQSDPNMQLLYIARTAANYEMISDRIGRNRVLTGPHDGAVVQAGPVVTRKAKGKAAVPRPEAPGRLLARLKEKLVLYDGTLQSLETVKELPGVAADVELSEQLDATAKYFVALKSLAIARSHTLAGNAANALALVKLANDQATEAAPGLTDADSESAQKKNSPLLSIHVSAADVSFLQNLLQAELQRARALVDIEKQQPSAGGAAKAGALALSETLGEYPQGRAVDLENIVTYPPRIQAMPVKPIFLDIAWNYIDYPSKAGGIAGVASAVGAAVSVAKSELSQQAAPETSSTPPPQQEQPAKRGWFGFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSW0</accession>
    <name>A0ABR3ZSW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="210"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="63817" checksum="9CA1C0EF67023CFD" modified="2025-10-08" version="1">MSGFVDYDSDDEGPDNALLQSFLPAAFGKKTQEADIDAQIERSRRPAWKASTAADEKEKTKKDDDSDSGNSDSDSDSDSDDGGDDLDRFPLSHELVFKTHDKAVTSVSLDPNGARMATGSRDCNVKLYDFASMTPTTLRAFKSVDPWQQGGKPSATTESHPVNHVAFHPQAATVMLCITAHPQAKILSRDGEVLTEFVKGDMYLRDMHNTKGHVGEIATGAWHPTDRETCVTAGADSTLRIWDVNNKRSQRDIIVFKSRAAGSAGRSRMTAVAWGAPAHGGGSDTVLVAAALDGSLVMYSGNNGPYTRPTAEVRDAHTPNSWTGGIDISADGRMVVTRGGDGFIKLWDTRKFKQPLVTVSHAATDAADRFPMANIRYGPNSTSILVGSADGSLHVLNPGNLRPEVVTPVTPGSPLIAVEWHAKLNQLVTGSANGETHVLFDPTRSVRGAADVVRRAPKKRHVDDDPSFTMDQSIGISNDNIVVPGAQQMASRRRKGVTNTGKSLDPRRPTMPQQTPFAHNGPDDKSIEKNIPLSRMLHEDPREELLKYAEAAKKDPIFTAAYKVNAPVTEYAELSDEEEEPDKKRAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTE3</accession>
    <name>A0ABR3ZTE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Epidermal growth factor receptor-like transmembrane-juxtamembrane segment domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_001177</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049328">
        <property type="entry name" value="TM_ErbB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21314">
        <property type="entry name" value="TM_ErbB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045674941" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment domain-containing protein" evidence="10">
        <location>
            <begin position="24"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment" evidence="11">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="205"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="357"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="435"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="483" mass="49115" checksum="9A3226D9B9227EF8" modified="2025-10-08" version="1">MKQFSNVTTAFAAAACLASVAEARRSPFFARNNAERNWQPAIETAAAVAIAAGQGHGDLSSMPQIAMNDFVDGVPAPEPPATTAAPALNPLFLKRDSSDNTCAYVSGISSISLYCDTTDECVANSHNSFVGCCPDTSTTCPIPTTCYPSSEGSLYTTSNGYTLWCGSSEYPECVTHYYADDVFTGYMLLGCGKTEAVDKVWYLPTSDSSSSSSTSSKSKKSTSTTSPSSAPATSTSPSTPTSPLPSTSPTGSTSKKSNAGAIAGGVVGGVAGLALIGLGVFFLLRRNNTNKVNNVGGAPGAPGAGAPGPNGGQPPMGQQPYYVAPGGGDPNTAGYAAAGAAAGGVAGLGAAAAYQQHQQQDPNLYNPNQQYGGYPPQQSPPIQQQDAKLYDPYNPNGQQYDPNAAAASASGSPPLVQSPQSGVYNTAAVAPAGGQISPHEAISPYSAPPPQPGMGFHSGPVPTTLDVAELSTERNDGELRELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU16</accession>
    <name>A0ABR3ZU16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="292" mass="32482" checksum="DBCAAA253704BDA1" modified="2025-10-08" version="1">MAYHLLRRPWRHRKIYYYTMIPELATIVALLVLFGLAQPNTYRTLMWQIGYNNGFNSNPNMILYAYANHVPLPTVPFVWSQALTDLNVAISVLSLFVLLAKMIALIMHVFFPVFGLVMSIPMTGLYIASVYGQAGPDYADARYPSPVPWYISKSCSYAAANNAVSDCMMAKGCFAATVFMLTVYLTNLGFAIYAMWPNKALDVVDDETDTDDDVPASSNKQWEMQPQGMRSPGLRSPRFGGGGGVLMSGAGQMASPFTPRTQAFNTLDRNASPFTPRTQAFHTLDRKLPLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZW27</accession>
    <name>A0ABR3ZW27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ATP5</name>
        <name evidence="9" type="ORF">Sste5346_000257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="232" mass="23914" checksum="BDA3B6340E9212CC" modified="2025-10-08" version="1">MLSRQAMLVARTAASRRTVAAAAPALMRGYAAAAAGSQAQDVKPPVALFGLDGTYATALYTAAVKTSTLDPTAKTIAALAALLAKDSKLGAILSTPTLSSADKSAVVAELQKSTNSANQPTVSHFLQTLAENNRLGLLGDVAAKFGELIRAANGEVEMIVTSAQQLDSKTLGRLETAIAKSAFVGQGKKLKVTNKVNPEILGGLVVEVGDRTIDLSVSAKVAKLNKLLTDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZYK0</accession>
    <name>A0ABR3ZYK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">WDR6</name>
        <name evidence="9" type="ORF">Sste5346_000218</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="974"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="381"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="546"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1355" mass="144414" checksum="45C204B567C99775" modified="2025-10-08" version="1">MATATSSSLVAQELTHKQMPSPQKLQRDDSSVLCPVTALAFYRLRHNAASQGGSPTPASDSEPSLLVLAGEDGWLAVYGATESEKNEGSGSSPRSLFGCRCYGRLRVFAEQPIQGCRVGNRGGISNSEDDEDDNILVWGGQSVAVVSRDHIVQLLEGSTADGATSRTSLPVVKEVLTPDWIYDGLLPRHSQGDSDGVSAGALITAHNEILPFRVDKSVVALLGIPISPSRPVLYSAQLAWAGSGDDIDGDGRLLIVAGTVFGEIVVWTCRLPTTDNVNKAELGIEVLDVFTGHEGSIFDVVVSPELKVGALLGGADSPGAQRRVRLLASCSDDRTICVWPLYLDRREGQGEEKKLDTHASNEARETGFQNTFEGLAQRIDEPIDGAKSQPRSAVDKLYKQNTSPPPPSTPSSSPALAAVMAHASRIWHVRFGEFSAEAAKDGNLLLYSFGEDATAQEWRLELGTQETEHSLTGKLVHLRTLSSHAGKNIWSAAVSSKTSSHGPLIATGGCDGKICLFEGRQGQSQPATSDANGLTNLLSGTIASSTIPPRAATTEPEVLPPPPPPAQEDEDEAALKTKKKKGGQKKVREDVFNSYAFLSDDQLLAATAQGRLLVGDLRQTSSETASLEWVELSGVSGDMTLSLKDYNVIRSPRGGGGGGVAAHPGAEGLAIVGNATGQLFLFSGRGGLQRLATTLSGKVDEIFFLPHTADEISDMEATGQSSINLEIIATTLFRDEAALLNLTVDVAKGTIVSESTRILKLPTKVPASPAAMVITAASRCLEYIVLGSRNGQLCLYKPVDSNDGAALSTFVLETQLQTHTRDAILSIVPLPPRSGQPPLSSASFVVAARDGTYRIYNIDKKNGTSAIRLQHETATPFGPIVRDAWFNESETPGEPPELVICGFRSTHFVVWNETRQQELATVDCGGTHRTHTYLFCSGSRSKSTSAGRVRFAYTRQSELHVFAQDVCVTVPLKIGGHGREIRSVRASAGGKYIATGGEDTVVRIWNSPRSDDNKSASTNRRCLSVLKLHNTGLHSLAWLGDDCLISAAGSEELFIWRISTITDSAYDGLAVLCESSYPDSTDDKILRIIGLDASLDPDNKDAMFVSVGLSNSILKTYRYATSSGWKLLAQGHYTGACPTQLNHLQLQNGGDLVVLAAFADGHLTVWKATPAPIESREIQALPNYADYSLLCATKTHQNAVKALDVVSIGHDAGSLMVVFTGGDDNAIAVTTLSSTVDRDNIIYIFGKTFRVSSAHAAAVTGARVLLQEEEPAGETSFTAVTCSNDQRVKAWRVIVLGVGSSDLSTAVRIQLLDDRYSAIADPGDVESIVSPESSGNSGSPSALVVGMGMETWKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGP8</accession>
    <name>A0ABR3YGP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-carboxymuconate cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000122">
        <property type="protein sequence ID" value="KAL1887402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932961" description="3-carboxymuconate cyclase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="40898" checksum="C9BF6410E3775712" modified="2025-10-08" version="1">MYHSTLLFLFLAPLTPLAEARPAACAAKGAKATNGKAVYLITNDQANAVVALPIGQDGLLKGAATSTPTGGAGANGIDGSTNQTAAPDALFSQSSLTIAGMNLFAVNAGSNTLSMFTINPLDPTDLTMVGQPIDIPGEFPTTVAASMKSKLACVGSTGAIAGVSCAPFSTQGLGAMDGLRVFNLGQTTPPVGPTNTVSQVFFSDDGSTLFSTVKGDPTKNNTGFLAAFPVEASSSPSAGAAAAVVSQQGTMTSPAGTAVLFGASTIPASNDLFVTDASFGGAVLSLDNKDVATVKGKGIVDGQKATCWVAISPATNTAFVTDVGTNRLVEMSLADATIQSQTDLSANGDPGLIDLRAAGNFIYALSPGNGTTQAAVTVVDALSKKQVQHLQLQGSAVDKNAQGMALLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGW9</accession>
    <name>A0ABR3YGW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short chain type dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="28882" checksum="20F9371EA6BD48B4" modified="2025-10-08" version="1">MASDDVQFPTYPDIKGKVVFLTGIGQTGDQSMWGNGAATARILARNGARIFGCDLSLAAAQHTESRIRAEGGEITVISANVTQNESVKAAVDACIEKYGRIDILVNNVGRSEPGGPAEMAEAVWDAQVDVNLKSVYLCCHHVLPLLEKQGDGVVVNVASIAGLRYIGKPQVAYSATKAAVIQFTKATAVLYAAKGVRMNVVVPGLMDTPLVGLLADKYAGGDLVGFKAKRNAAVPMGHMGDSWDVAMATAFLASQQARYITGQPIVVDGGITSSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHT1</accession>
    <name>A0ABR3YHT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-1,3-mannosyltransferase CMT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF5">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE CMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047444009" description="Alpha-1,3-mannosyltransferase CMT1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="48057" checksum="9BF6FF40240C5D61" modified="2025-10-08" version="1">MRRKYLFVGQILLLLLVASALYFGSHHITRLPAPIRLPVGDSSSNNGSEGSKENTGSSYTYSGVISAENITRYVNSIFDSKSEDLPRLKCPDIPSPSRYDSLRTSATAPENGPETKYFFAIDLRDTVTLLPRLLGSVVETIKFLGPASCALSIVEGNSHDGTYDVLQAIRPALDDIDTTYFLRSSDIDPKEGDRIAKLAKLRNLALQPLIDGNVPGANEETTVVFLNDVAACTEDILELVHQRRQLGADMTCGMDWVYVGEHPTFYDVWVARGMNGDSFFEIPADGNWNSAWNLFWNNGDAKASLNAHKPFQVFSCWNGATVFTAKPLLDDASSVRFRGPHDGECKQGEPQLFCKDLWFHGYGKIAVVPSVNLEYSDANAQKIKDLKGYTSRWTSESGEEEGKIEWNSSPPENVKCIPSYENQTFRPWNETLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHX1</accession>
    <name>A0ABR3YHX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Centrosomin N-terminal motif 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009922</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF63">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="5">
        <location>
            <begin position="433"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="338"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="575"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="659"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="768"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1375"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1488"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="608"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="694"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="806"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="659"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1410"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1427"/>
            <end position="1445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1521" mass="169370" checksum="F985E04238680275" modified="2025-10-08" version="1">MDVGNVPLMASHDAHHGDGHHGAADHADNTGAFDDSLHEALTSKSANTKSHSDPRSTTPPPPPLAAVQPPPTHSLQDHGDDTGDDMADTTGGTEQEETQSTNINTNANTNTDGAAAAAAAPEESFAASFLDRTGLDNDKASDSFNDAQFRMNDTLPDVESSFVAPLSPLPTITQDGPDDTYLFDSPRKRQPQQQAAPLAPVVDEPEQPQSQEDSLLWPEQQSTQSKGDESRRRSLNLNESTGSGGSNGLALRYGKRPRFLRSRNASQRSSASSFITNPDAHDAHDENNREDGGNDVDSDVTVGLGADYALQSGGAIPAGGRRNASDLLSRTVSMGSVASSTLDDNNNNEDLLRTPRPNKATLAPPTDTVLTRRVMDIQVPESLAREYKTRNGLTTPQPRKVSDFRSEFNSTTQTAATNATATTTATRPGRNMTLKEQSSTIERLSKENFDLKLKVMFLSDRLDKLSEDGIKEMIQENVEFRTNIAILQRDNKGLRRRVKELEKKIRDDDDNNRPGTSRSANSSTEPDDPDAAAADQEREEEVLYLRERVEEFTTIIEQLRQDVFTKEAEKRRMGDMIKSLQSNTAGDKGVNGESLGRQEEEDVWKDLLEQETARREQADDDNRKLRDEIFRMKQEMHTTNGGTVSSNGERSLHHTTNIYNISKRANGQNTNTNPSVGGSIDTDASATTGSATLIEELRREGEQLRHENAELRKEVGAQTSMLTSRNREKERLYQEIEDLKMAQRRGGGPAPSTIDSLLDRSASQIGMGVRERSGSRASGGTRADTVLGGTATGAADEQDQFDREAREDLENRNASLRDKINEAKLENQTLLQELEATMLQKQEAEEVALGVQKDYEGAMTDLMAMQAERDELIAELNDLEQKHSNLQGEFEELRAEAQDAIDGYEEDADLRDAENQKLQTDLAEKTENFGALQEEMRKLSEALVGLEDETENKVRRVQQLESELSDANKELEELEAKLLESNDKAQRLLVQQENSQGEIAFLREEQESDKINISRLEVSITKAEEQIRDEQERVKQLQQQIVTERERSESLATKDKKEMQQFVNELSREASGHKEEARKLRKSLTSREVEATEWKERLMELENNLREALGDLSGTRSSLLKSIAKLQRELENTVRELQTTKGNLMEKDRIIKQRDALLESHGLEARKVAEALDKERAAHRNTKHQFDTFQKTHQHVTRTVTTQDARITELESSKSLDKRRMSQLESTFRDQLTERNNLLLLLWTRLSAICGTDWAHDNSLINGRALPSLEVVATMLPGFTRNLMAAIKHIETVVGGFPARIKAVERDLWREYQSLESTLEQRLKKLDRLEGVVRNNVSGGGELQSRFLRLEEAYRQLKVENTTLRTASDVRARVYGSSATGTDGDNPFDLPGGGSPSPSIPTGPRDRSAKSSSSRGKSGRSGVPRPITSSSSAGAHLSLTSSSARPLTAGELALHEGDDNNSSGSGGGADPRWILRLRDLENKLKLEREGRTMDRNEAVRRLREQETELQRRSEREKRREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ32</accession>
    <name>A0ABR3YJ32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7871 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057193">
        <property type="entry name" value="DUF7871"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620:SF1">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25277">
        <property type="entry name" value="DUF7871"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7871" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="80" mass="8189" checksum="AF72466BAF190288" modified="2025-10-08" version="1">MVSSNCCKGGNAAECICAQNATCSCGKQSALHCNCDRASAENTTSGDRCSCGQRPAGACTCATNPSEVNTANETDFTTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJB2</accession>
    <name>A0ABR3YJB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009892</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="148"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="590" mass="65950" checksum="452CCB1D150719ED" modified="2025-10-08" version="1">MYDLIRDASVGQAIRFLTRNRVLKYPEEEEDYQLPQQYVDILSGREKLEGDTAAPISSNDTPNNNNDDDDADVDIEILGRTHTRRSSVVGPRFSVERVQEEQEIRMQRTKSVPIVPTKTADGVVLVDWYSTDDPANPQNWSNAKKYFILFVLCFYTWTVYCTGPVYATAEKGIQKYFGVSAVAASLGLSLYILAYGIGDLIFSPLTEIPVIGRNPVYYLTFIVFFAFSFGPTRVTTFGGLLVLRFLLGFFGSPALANGGATVGDLFTIINIPYGLCWWVFSAWTGPAIGPLIGGYAAMANGWRWPMWEIVWMAAPTLVLLLLFMPETAPATLLLQRAHRLRKLTGDARLQSQSEIDQKHMTASAILGEALIRPMEIMFRDPSIFFVNLYTGYFYGVFYTFFEVFPLVFPVLYGFNLGETGLSFLSCFIGVCIAIALYTAYLYFYMVPDNLKHGFREQEHRLVPAIFGSFLMPIGLFVFAWTARTTVHWIVPLVGVAIFVVGHFFTMQSLFIYLPFSYPQYAASLFAGNSLWRSGVACGSVLFARPLFINMGIARGVTLLAGLSVAGIFGTTAIYIFGKKLRARSKYAVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJE7</accession>
    <name>A0ABR3YJE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF2">
        <property type="entry name" value="HYPOTHETICAL POLYSACCHARIDE DEACETYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="270"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="60650" checksum="5983F557246027D9" modified="2025-10-08" version="1">MSVYLSGHKAILSGTLAPRASALQTELVAACGEGNTAALNLDGLLADGGSLSPEIEATRQVEAAFKTLGNSVSLFVIDARDLEPSGRDPIWEVPLDEWNQHKASTQVVQQRTLLQVKLLLQQQLTLSKAGNKLPAFFLVIVGYRDMFDGALDPVIAKLQRDVAWLQRESSVAFLDLASTASEPTEGSIGAAIGILAASRTSHGVTSINAVWGLRGANTNSSSASDAPDVSDLTIHPTLTKKKPTVKIALSFDFDALSAFLGTGDHPDNNMADYSTGVFSGRIGARRLLRMLQKYQVADKTTWFIPGHTMETFPDTCKEITASGAEIGLHGYAHEGAYQMTVDQERDVFTKCVEVHHNLTGKKVMGWRAPMYQLRETSVALLKEFGFLYDSSLSHHDSQPYFTPNDPPIERIDFSKPASSWLKPTPLGGMYECKDGYPLVEIPIGWNNEDMMALQYYPHVANTNGNVDARVVEQRWKDIFLWQWENGKMESDDGTFIFPLLMHPDSSGLAHVMAMADRMVGWLRSWGDSVQFATYEEIAREFIAKKGMTPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJI9</accession>
    <name>A0ABR3YJI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000094">
        <property type="protein sequence ID" value="KAL1888348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="547" mass="61220" checksum="96D20258BFCFDCC3" modified="2025-10-08" version="1" fragment="single">MPSIRKSGSADSTGSSPNSSPSSSHESKGRHSSVLDAVAFSSQSTAPTSLSGSPRLPESKPVPSSPPPVYYEPREDLSPSTMCYPRASVDTFVSGVDSEEELDHQQQHQQPESALDLTDDDDVSQDHYREHRLDTSADSIPPLPEYRHDIVDRNVCPATPQEFAQLFPSLDRMSIRHDEFTADGNMNLRVDVSVPMGRRRIPTSYQLFHLRMYDLAKREFSMRRYSRDSGREVCNSKRTFIDPSEKKQKHKVGRISRKSSDEANLKHWGRSSTSSNATNNGSADIRPGLQRSMTTALRSLSAMATKPSFRRSNSSGSNYQDQRPSTSHSPYGNHHNNESTTSSSRPSLSSSTPSLFGRDKSRSAHFPPPPKPTNTIKLEFSNYARVDLEMRGGHNNGHDNTRYEFTWWGHKYTWKRAVEKHLNVVSYHLLRDDNGENPIAHIVPEMRSPNQVDADEEAGGWIPPCHMWIADPSVLEAMTDVADVIVSTGLVALTDDCIRTRWQPRKAHGLAVPLISRTLDMDVNPRALMQHVFHRRNSSGSNSNNHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJK4</accession>
    <name>A0ABR3YJK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000091">
        <property type="protein sequence ID" value="KAL1888489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="35"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="498" mass="52733" checksum="18A813F695245973" modified="2025-10-08" version="1">MSGSQTNSAPSGSITTSPSVVPFILNGKDVVPPTTDRTFPVVNPATGKTVHHYSGAQPADATAAVEAAKAAFPAWRDLPPRDRRDLLLRAAEIMKRRRDELSGYLETETGQPRAWADFNLNTAIDFIIDAAGLAAKANQGRAPITQDPTVGAIVMHEPYGVVLAIAPWNAPYILGTRAILFPLAAGNTVVLKGTELAPRTMWGIASVFVEAGVPPGVVNLVYAAPGPDAAAVTETLVAHPAVRKINFTGSTAVGRILGKLAGEHLKPLLLELGGKAPAIVWSDADLDLAAEKVALGAFLNSGQICMSTERVIVQRSVRDAFSQKLAGAMAGIFGSSTEERGAQVLIRPAAVAKAKSLVEDALSKGAKLEANGDLKTAISEDGGRFRPLIVSGLTKEMDLFYTESFAPTVGLFEVDTEEEAIALANDTEYGLSSAVFTEDLRRGLRFARAIEAGAVHINNMTVHDETILPHGGMKSSGFGRFDADLSEWVQTKTITYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK65</accession>
    <name>A0ABR3YK65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Carnitine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CRC1</name>
        <name evidence="14" type="ORF">Sste5346_009495</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF4">
        <property type="entry name" value="CONGESTED-LIKE TRACHEA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="80"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="179"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="287"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="377" mass="38921" checksum="BBCBA9036B7E6B58" modified="2025-10-08" version="1">MSTSDNGAPAPVPVAPAEPPAAPAPPTPAPAAAPATTTSKIVEAAKAEIKELKADAIELAKKADDVVSLPSPKEATSSLAAQARSFAAGGFGGICAVIVGHPFDLVKVRLQTAEKGVYSSAIDVVRKSVAKDGLRRGLYAGVAAPLVGVTPMFAVSFWGYDVGKQVVRKFSTPNPDGSLTIGQISAAGFLSAVPMTAITAPFERVKVILQVQGQKVLKPGEKPQYNGAIDVVRHLYKEGGIRSVFRGSVATLARDGPGSAAYFAAYEYIKQKLTPKDPVTGKPNGQLSLTAITVAGAGAGVAMWIPVFPVDTVKSRLQTSSEPGMTIGTVVRDLYGKGGFKAFFPGIGPALARAVPANAATFLGVELAHQAMNKMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK87</accession>
    <name>A0ABR3YK87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_009669</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="168"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="519" mass="57652" checksum="BF6F140F16659EBA" modified="2025-10-08" version="1">MEPRYLGSSSAFAFSRAIGSSFLLRDASKGGSSSKGEGTNATTDDPGTQSPINVPTYEDGLVLTNAYFENIHIQYPFLHEPTFRMWEVQRVSTLPVPVSDPDVASFFVYIIYAIGALLMPTSRYNHEQLYMLAMRYLDAVLQKDNLQSVQALLACCIYSLRSPTGPSLWKLTGFALRQCIELGYHRNVKSFGPQMGAVQVELRKRAFWTAFAIDCSVAMFLGRPLGVSIWEIDVELPKNIGDGNVFATATNNNSGVAPPAPDLSVALHMFRLRRLWAKVHVALFTDTTRIRTTDEEYTARIRQFQVELDEWRATAPPEPPRTGEALTLFGSNDWYNSNYSHSVLLLHRNQLIEARSAVPAPIVIACLEATECISRGYYRQFILGHVGCTWGCLHVLFLAGLTYLHCLWTSAAARAARPLNSVTNTCMDCSMVFAVMAERWDRAAAYRDMFETLSRKTMAMLVEVGVSDSEPSMSAWPGSVAGASTIVAESGSLEDPWEVMQWINEDLLQPGEDPGTFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL74</accession>
    <name>A0ABR3YL74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="44228" checksum="014F8664443ADA70" modified="2025-10-08" version="1">MDVTAARQAMKVLLEPYAGNRDKTAREEALQVLRSINDLEALQELIQVYPKLLTLESPSEGLCPPLVEAVKRGRLEIIRALLKHRVTMPPEQLVPPLYHQYEDNGFRGHWGTPLTTACMLGRHDIVRMLSDGTPDVDINEVDYDGYTPFLSAARGIADETEAQTRDRLAILRLLMDRGADVHAVKADSLRNSETLDKEFDEGLVHRPFVFRPRPGGLGNALSLAMEVVELNTSILQFLVKEAGVNVFKASLRTYQHFAYDHAFITPLGVGARYGNIKGVETLLSLFPDAEDHIRLLATTDATIVPEPRPAQQSPEDEMPVLFPLHAALLGKQKFRAPWGADDVLTTNETIRAATINAAYRQHYTPLHMVTSFDRIPLLLEVVKLGADLDTPAWMATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLA2</accession>
    <name>A0ABR3YLA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_009077</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359628" description="HMA domain-containing protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="10">
        <location>
            <begin position="59"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="694" mass="73242" checksum="284C7B288296067F" modified="2025-10-08" version="1">MARCYIAASMIAFILRSADALDIGLDIQYNDEVTHNYGGEYGEEVEIEMKSGKEAPTTPLLLVTVSGMTCGACVGTVEQAIKEVDGVDDVQVSLALQEARVFLSTTKYDDIQSKIVAAIEDAGYGAVHAGCDAPPPAIRLAMLQHTDELARLRATLTGLGQYGTAVFALGTGARLSGWMTSIAALERTRSLVLLGLTMAAVWTHARWILESAWKAAKAGRATMHTLITASTLVGLSLGAAQVLFGSTATGTHYDSILGVLLIVGLGRYMDLLSRKRATRSFAGLYTLLEQTSTVELAKSGGDANKTTKGRKIPAHLVRPGDEIVIHPYRLVPCDSYVVSGTSHTNEAIVTGEARPRPKGVGDRLLAGSKNGPGLLRAAVINNDDGGSFLAQLVSRVEGALASKPAAQKKVDGITQYFVSAVLIVAVVAATVDFYSVSHVGLSSALTAAAEKLMVVLAAACPCALGLAVPCAVMAGIDVAWQNGILMLQGAETMERAAATTHVVLDKTGTLTRGTPEVTDINTHDNSKKDTQTLATLVCAAEVDAMANHPLASAVFRHMLPLCGEESWRAFRSGGGQSSDIKKVPGRGVQCQVTIQETCRHVVVGSLTYLQETGVEALPTDPTATNEDDHGSRVFVGVDGRCAATLTLHDKPKTDALQTLAALRRRGLHAGAHHTRAPLYTAQINVHRSVQNPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLF5</accession>
    <name>A0ABR3YLF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="290" mass="31701" checksum="5939ED6E670ED71D" modified="2025-10-08" version="1">MLFHPPPDMGFFDLEGGSAITGVSRKSSRHHSSSSKHHSSGHRERERERERERSGHERKRSRSRSRSGTRSINISARSFFGLDDGHSSKKHHSSSSHHHSANKSTGSFFSLPNVSTRSIFSSFGRAGHGGSSSSYYRRSPRSNFMQRAYKKLKRLIRDLIYYAKKHPMKVFMLAIMPLITGGALTALLARFGLRMPQSLERMVGVGARAMSGDSVGLVGEAMRMAAVAGTGTSGAKAMATSLERGRNGNMQWERRSVERDYFGGGGGHSSRSDSGSGWGGSLAGITKMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLJ7</accession>
    <name>A0ABR3YLJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromosome segregation ATPase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1185"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1961"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2045"/>
            <end position="2189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1868"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="291"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1987"/>
            <end position="1997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2045"/>
            <end position="2058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2085"/>
            <end position="2095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2096"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2136"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2161"/>
            <end position="2181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2216" mass="243118" checksum="D3267B0252843AE5" modified="2025-10-08" version="1">MPPIERDVALWDPERVLRHQHSSSSDHGRSFIPMWDSSDPERAPPPLPLNPQSPSVGTSRPGTSTAIQSAHAALTEKARESALVSNALARRVGEHSPERTPRASLSHTSSISTSSSSSSAPRSQSHRRMQSLQPNSVRDLSLMIETSGANSNNGRDSNNSTPRSPEKTSLVNLPSTPLRNRSDPFLSDDKQPISTNPGPGPSLTPIVRPIVRRPHQSILGENTPPQSATMLALHSMAASSPSQKEREPGAPLPMPPSSSSSQSLPQPPPQQQQQQQQQPTSQPDPTPAPAPALSIVSTNSSAGGAKSRSGNSSSGSGNNNNNNMAMTVIKQPHLQMEHLSKQIFSLTSIATSLQKEMSALSRRSRDNATDLLSLKEATNARDEDIRKSLREIISNASEVTSIRSRDSYPGGPFMIDNKPHGQPQATSPLSKSVRPFSLPRIPSPNSFAASLDRESMSTPSLYAADGPNTISMLERIVREMGTKEGQDMLMGRLSEVIDKVAGMASAAKLEELLQIVKERQEQSVVPVSQGGNNYMGGGPGRPRNYSFDDEPASSQREIEYNRKGPMTQRAERLLQSASASAIDQRRSSAPTTGITDVISDDVLKIIKTVKDSVAQGGGLTAEVKALVRELRGEVLGMGREIGRRLDEVEVRAKDEGKPPAATQVEMAKVVEDGLSELKQHMNDLMREHRRQSAASAATIAAAAAEAVPAVDYQEVYNSMRAALKDSQANKPNRPELSREDVIEAVKDAWETYKPEIEVQQIGLERDEVLTCLEQGLRDYAPRSEQPAGATREEVFKAVVEGLTHFVPPQMPSSGMSRDEVLDAVRECLEEFEFPVAPSAIGAEISKEDMVDAVKQGLNGFDFPQTSRDLISMGPNENSDEIVSRLHDIMQFMREEFKAVSDEAKQNVAANGRDTEQVLDATRDGLEKLRSDLEIYVDKVAAAVTHQDFSEGLIRTLDVFRDEISDLVSKASDGSKEMLKEEIESLRDTVNTSLVPAIPVQSNTAPANNREVLEALQEGVNLLRGEISSRHVNSTSEVLDAIQEGLSDLRISIDRLGNKPADLSANDEILDALKSGLSDVRTDIDGLRDQNSNAVATVETSNTAIVPADMLRHDDIKNLEMLITQLRTKVDVIDAARSEQTSDREITTTSDEDPSSALTTERDAEWKEKIMEMETKLHAIHESVTGLASREVPPASTVTDPEEAPAPRPSTDAASREDVEAIETILRNTKARLDDLIDGDQFLRKDHIETIETLVLDTKHSLVDLKAQMDGLSSREDVNMVESLVAQVANGFDELKERHEKQFDDPERVTKTDVDAIALACLQVKSAVERMSQADDSTGLPSKDDLLSLAVIVRDVRSQLEMDSAVAVKASEECQAEVAGVGERVQDVKDFLEVLNETVKNRLEDGVLGIESVGKILDSLSDTIGRNSSDLHDLYETMRNEFEESRAGVVGAKLESDERIQQTTDVLEAKIDERIGELVAKFDDFQAIADDRMRISEGRDVDMEAAVVGTKDIADELKLLIDTLGSAVTESLEKMEEASKTVFERVDDMASKAEENHSDGKAEHQQTRDHVLQAIEAVQGVQGHVTEYQPKILETIKDVLLVVSEHFEHSKSSTTTIQEQLVEAKAPEMPLLPPIEKYDDTTMQEKLDKLVGQTDRATDALTKLDKMDSLVDHTLAVGQALTKLDRLVEHSEDTDKALGEQREKLDQLDQLEKLEKLEKMDYLVAQAETTSQALVSLEKLAKLDQIVDLTQLAGRAFDSQHEKIDKIVEHTQVAQEAYTKLDSLDQLDKLDKLEKLEKLDQLDELMGHSRVADDKADRTLSQLETLEKVHQQVMRTAADLAQYMSTQTQRIADDHEDRERTLQETTIALERRQVEKEQAEASVEALREEEHRLKESVASLRAEQETFQRNKIRLTADVSSLETALHLRREELHEMEARAEGLERRILEGVMDHSRVLLMAKTNKGREAMNRKRVVPSKKEAPPTGDNTPRAATRAAPAESKPRSAFNMAMSAKRNPLPTNSPVGVAANGSANGSRRILSLSQINSSVSSGSIKRSNSVRANVGGPGGLRKSSWGGRLPTKGYGSLEMDKENVPLKESDEENDRDMPEGDDDEPAGYNTPRGEEISAAIVPYKRAGADDFDDCCDDDDNDKDDDKHSEAGTLRRSSVGTSVVTGDAQSETSEFYSGDDDDDNDVMSQWTSSEVSSAAPGEMVLYGSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLM1</accession>
    <name>A0ABR3YLM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF1">
        <property type="entry name" value="ISOCHORISMATASE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="26"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="222" mass="23870" checksum="FA14ABF65A4DB7D2" modified="2025-10-08" version="1">MDNHAEAKSYAASGYGRRMGWGNKPALLLIDICKAYWTPGSPLDLSANKEAVGVPASAERLVKAAREGGCPVAWTVVEYTQPDMSDAGLFWHKAKTLEVWQVGSELNQKGLADFVSERLTPQPGDIVVKKRYASGFFGTTLATELAVKGIDTVVVCGVSTSGCVRASTLDAMQSGFRPMVVPSACGDRSKAIQDANLFDLDSKYADVVTEEEALEKFLAGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMN2</accession>
    <name>A0ABR3YMN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF51">
        <property type="entry name" value="SNF2-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="972"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="877"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1201"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="881"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="901"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1212"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1229"/>
            <end position="1239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1270" mass="140373" checksum="BEFFEA872630D508" modified="2025-10-08" version="1">MSYDPGETIPAKGIPLSDYIPVGSFSFCPHGAGLQGPLRWQYSPQPSQIPAAEGDEHLELLSEGDLRALFHDDHDKFQEAALSQSMHNLFTARWIRFAVKRRPGGYDLENEGGAICRVYVLPDDLHRIEVARRNEKTRRDLRDVLSRLNCTQEQWNGVETDRQLNLDDAQRVVDEDQGSSPAGQSLLQMFNTIPSPSPRTDLINDDSYQRVLDALMSSSIPGLKSTTTLYSHQIRSAAVMLQRELQPGRVVDPRLICLQDMLDQQPSTPGDHEGDRERSEEKRQWYYDDVTGEVLRTARLYDGVSGGILAEEMGTGKTLICLALILATRTFPSEFPDVYVERTYGDTSQQKGPRSLLDMAGRVVSRQSVPWKLYLADTAANAEDFRHCIDAIQRNPAMYAVPKYKRPGRESSRMRTSSTSAEDWSANYGPTITLSSCSLVIVPANLVRQWEEEIAKHTEGLNVIVVSGIRAPVPTTAQILAADILLFSIPRFKKLVQDRKVTRDGYELESPLASVHFKRVIVDEGHHIGNSNMGRKSDLLLVLDCLQISARWIVTGTPSTGLFGVDQAASEASVYEEYTSLSSRQPSPNSAASLQERKDLERIGAMATLYLKVKPWSNAKTPDWQRPMGSGFGDTPADWNVYVMQPHHSNKSSGRRGVLRATLDSLIIRHRTSEVGDLLPTVDERVVVIDGSYQDRLCLNLFSMMIVFNAVQSQRTDQDYFFHPKQRGALLTLLKNIRQATFFGANFYSATEIATALETAEKFLEDKKVPISEDDEALLKSAIAFGHIAVANRFKTLADACHEVPIYVADMPGGGPFAAAWSIDGHSPSGKDGLTCTVAPMVRALQQYLRPCMDAPTSLRAMMDDGRYEHKGHDVLRRQQESVQKQAGRPSNSTTVVNGDTATPATPATPSKNDPTLAGNTKLGEDNHAGSLKKRSTLDTGITVNASSADVFLAAPLANTRLVSTASAKLSYLLDAIVRHQAEEQIIVFYDNENVAFYLAEHLEILQIQHLIYAKGITAERRAQYVATFNGDAKTTESTKSTTTGSDSSTTSPFRVLLMDLSQAAFGLDMRSASRVYFTSPVLNPQVEAQAVGRVRRISQGVAAKGSKKRVLHVETLVLRDSLEEVIVDRRQALSAVEHRRIKTLLDDGPIYEWVRNARVGYIAGDADAVSQMAPLKEPQFLFGRGFGRVVHPDEGLVVVERPGKDKNIDQTSSSASTSANSSANTTAVNTPKATTPTPNVDEHPPKKRKLLPKVTVRFGWVEGKETERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNT1</accession>
    <name>A0ABR3YNT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009134</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="689"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="750" mass="81339" checksum="D665D87520AE591C" modified="2025-10-08" version="1">MASPNPTAAISTASPTSSATTLVALSTSGTAHTTPVKPPRHRGTKACRRCRRLRNKCIHAQGQTPCQGCVAAGPDTAASCAFPARGERDVDREFRRRPRPNPQRLASQQRPPPQDLPSRLPPPGINSTAWPPHDEVVDGCRTFVTCYFQLGFLPRSLFLERLVQSPEESDYGTGRFLLSTLLAISSRFTPCLVQRYGSRTAATDHFLALAQSQALTEMYAPSLERTQAFFLLSIAEWGNSDRDRSAIDMAVALRMALLLRLHKEETYAAMVTATSTPAAATPTTGTPKPRTGTVGTTPRPATTAITPTMNSAALTPTPRPSPVPSPATSLGASTATADHVVRLESARRTLWMIYSQENLHSGTSSPAPLSLEDTTALLPCNEADFSFGAVPSFRAALEGTPPANENPTLAVHPDRCLFATLIQAHSLWGRVARHATRASLGSGPRPGPYATYTAITDTLRRWEATLPTRHRWSLWNLRGWRSEGLHLAYLSVVMVLRLSNIVIRRVYLDEMIAALGPQSPVVTTASPIPTPPPPSVTSTSAWQRISYELFDNVVELHEQVTAYFSMRTPDEGFPAILVFCVYMCGSLASYLWHNPYLCPHVSPVEAEEMALGTLRILSELYTAWPASARWEEVLRRVTGPSTDAATIMSGEQVITAAVVDLPVTSSMAVDLPERPFPVTTQDVTAPLTQDSRSVSVVSGSGRSSTSTAGGSEQDDLRPLIITDFPSDLFNAELADYLNGTIHYGLLDGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNX4</accession>
    <name>A0ABR3YNX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 11">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 11">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">tmk2</name>
        <name evidence="14" type="ORF">Sste5346_008481</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 11"/>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07857">
        <property type="entry name" value="STKc_MPK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="368"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="419" mass="47460" checksum="54A0E9E06ECC7158" modified="2025-10-08" version="1">MADLQGRKVFKVFNQDFIVDERYTVTKELGQGAYGIVCAAVNNQTNEGVAIKKVTNVFSKKILAKRALREIKLLQHFRGHRNITCLYDMDIPRPSNFNETYLYEELMECDLAAIIRSGQPLTDAHFQSFIYQILCGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGFSVDPEENAGYMTEYVATRWYRAPEIMLSFQSYTKAIDVWSVGCILAELLGSRPFFKGRDYVDQLNQILQILGTPNEVTLARIGSSRAQEYVRNLPFMPKRPFPILFPNANPDALDLLDRMLAFDPSSRISVEQALEHHYLQIWHDASDEPDCPTTFNFDFEVVEEVEEMRKMILDEVYRFRQLVRTVPGSAGHAAAQAAAQQQTGQVPMPSGGGQWTAEDPRPQEYVTHPAGLEQELAGGLDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA2</accession>
    <name>A0ABR3YPA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008709</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF78">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="26"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="555" mass="60372" checksum="B17337DAF1D4C916" modified="2025-10-08" version="1">MFAVRDQRSRWLITSKLETRKLLIAVNTLAGLSIFFFGYDQGMMGSVNDAKDYLETMKIGYVNDNNTAVVTNTLLQGGIMAAYYLGTLLGCLLGGAMGDRIGRIHTIAFGAAWSIMGASLQSAAQNSDWMICARVVNGIGTGVLNAIVPTWASELSHYASRGAFIAMEFTLNIFGVVVAYWVGYGVSFVDGGETSFRWRFVVAFQIIPLIFLLAGSFFCPESPRWLCTVDREDEALYVLSRLRGGSGGADDEATRRVHGELQDMKDVMALERGSKTSYWSMLVGSKSADGSDLHIERRVQLVIWLMIIQCWTGIAGITMYGPTIFSIAGFNASKALWISGLNNIFYMFATLVCVVTIDRIGRRWTLYWGSTVQGIVMFLVGGLSRAGLNASAAGETSKAASFGAGAASMVFIYTSVFGATWLTVPWLVPTEYFPLHVRAKGNAWGVVGWSIGNGTLTLVLPYIVAAINEKIMYIFGAVNILSIPVVWALYPESSQRTLEEVNLLFTAKTPWTWDGEKKFAQLKAENPGLAGGARGQVGKGVVAAQEAAQELEEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPY0</accession>
    <name>A0ABR3YPY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF31">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="24"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="396" mass="42441" checksum="8A3D886D2BAC7908" modified="2025-10-08" version="1">MASEAPLVPSTSSTSSSSSATRALTAQCFCKAVHFTITVPVASLPLGVHLCACSVCRLTHGSYTCFHAPLPAGVTPQFVAPSSLVGSTTGYRHATARATRYFCKTCGAHIGDDDFDGDTQTTPENAEWRVSSSLFDAGLHDDGAPGQAFSLRTHAMTDSAPSGFHEWLPQLGNRVLTKWNPKPGDAFYPPDTAKPYSPTTPEHDDQGREVLRAACHCGGVSFAITRPSDTPNLAEIARESGLRLSSEFPDRWIGCLDACDDCRLVDGAHVVGWVELPIAAFSPAVPLDFRVGTLTQHRSSDKALRAFCGVCGATVLFRRTDKGDSLTIDLAGGLLQAPEGVSAHKWVHWRDGRVIYLPSAERYHADFANSLKDGFAAWAAKTYGTGEKTIDQKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQS9</accession>
    <name>A0ABR3YQS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Putative oxidoreductase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="7"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="267" mass="28887" checksum="83227390B1AF82D1" modified="2025-10-08" version="1">MKDLKGKVSVITGGGTGIGLAIALELAKAGEAKLIIASTNADRLEEGAEELRKAGAEVLTVVCDVSNRADVQNLHDKATEKFGEVDIVVCSSGVTTGGPYVNHRPEDWDWVFGVCLYGPSYCIQTWYPEMVARKSGHIVLVGSQAGMNPTWFAHHGPYTAAKSGVMALGAALRLEALEHNVGVTSVIVAATTTNIMKCERSRPEKYGKSQPFDAEKRAARRIPAADVGRMTVQGIIDNKEFVATHPELKQMQKEYFDRILAAYDHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQW0</accession>
    <name>A0ABR3YQW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">beta-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_008079</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF3">
        <property type="entry name" value="BETA-GLUCOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="10">
        <location>
            <begin position="57"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 3 C-terminal" evidence="11">
        <location>
            <begin position="330"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="404" mass="43461" checksum="CC860FB545EA4E50" modified="2025-10-08" version="1">MATTAPSQTCVDVDKLVGKLTLRDKSVEVVDVQEILGQLTLEEKVSLLAGHGLWRTAPIERLGIPSVKVTDGPNGARGEVFTAGTKAACFPAAVSIAATWDTSLAKRIGKAMAEETKTKGASVLLGPTVCPHRSPLGGRNFESFSEDPLLAGLQSAGVIQGLQDNGIAATIKHFAANEQETMRNTVNVVVSERALREIYLKPFEIAIKKSKPLSLMTSYNKVNGLHVDQNPHLVKEILRDQWGYDGLVMTNVISVDLEMPGPPQHRILAAVESAIVGGSLGISSIDERVRSILQYIKRVEKFEHPDEPAETAFNNPEHQRLIREAGADSIVLLKNEGGVLPLQTASLKSIAVLGQSKTCFSNGGGSANLNAHYKVTPYEALTKAVGETVELRYALGMHTVCPYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR56</accession>
    <name>A0ABR3YR56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA 3'-terminal phosphate cyclase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00875">
        <property type="entry name" value="RNA_Cyclase_Class_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016443">
        <property type="entry name" value="RNA3'_term_phos_cyc_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03400">
        <property type="entry name" value="18S_RNA_Rcl1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF1">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="7">
        <location>
            <begin position="211"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="43114" checksum="E1169908A5251F4C" modified="2025-10-08" version="1">MAGPSGSDFVRFTGHRFLAQRLLLATLTGRPVHISGIRSSSPTNPGLAPHEVSLLRLFDAVTNGSSFQISYTGTTITFHPGLITGTVAGAGATEDDVIEHHVPAGCTRGITYFLLPMALLAPFSKAHVNIRFSGPGVITSATDTGDISADAFRLAILPLYGLFGIPPARIELNIRQRSCPGSGDRRGNGVVELRFASQVRLPKTLHLHRGAGRIKRIGGVAYSVGVSASNNKRMIHAARGVLNALTGEIKIAEAPPSKDDGSGEKPGIGFGLCLVAESNVNGVVYSADVVSPAAGGVLAEDIGTQCAHRLLESIAQGGCVSWTAAPTVLTLMAMGSEDVGRLRVSRDVVVAEEVMGLARDLKAFGASSWGLRQAEDDLVGGGGDSDEDEGDAQSKHDVLVSIKGTGLGNVGRKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRQ6</accession>
    <name>A0ABR3YRQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008205</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="109"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="440" mass="47791" checksum="85B2139A654E231B" modified="2025-10-08" version="1">MKITSASLPRRVLRAAASSQSSQSLSAAATTTTVSQSFFSTRRRQQPQTLSSSSPSISRRAYSSAAPANARLNLPIDYGTTPLLAHTSQAALSNTELPADIRGGATKRMNLYQAINDAMSIALAEDESVLLFGEDVAFGGVFRCSMNLKDTYGDERVFNTPLSEQGIMGFAIGLAAEGMRPIAEIQFADYVYPAFDQLVNEAAKFRYRDGGNGRHVGGLTVRMPCGVVGHGALYHSQSPESLFTHIPGLRVVLPRSPLQAKGLLLAAIRSNDPVVFLEPKILYRAAVEQVPVDAYELPLSKAEILKEGADVTIISYGQPLYNCMAAIKQAEADFKSKGKNGNFSVELIDLRTIYPWDKETVLNSVRKTGRSIVVHESMVNQGVGAEVAATIQEDSGTFNRLEAPVMRVAGWSTHMPLAFEKFNVPDVARIYDAIKTSMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSP3</accession>
    <name>A0ABR3YSP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007949</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF80">
        <property type="entry name" value="GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046974041" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="637" mass="68000" checksum="F7862CD268B33471" modified="2025-10-08" version="1">MRSALVSLAATALMVAGASAGRMLDASVAADRAASDNTTYDYIVIGSGPGGGPLACDLARAGYSTLLIEAGDDQGDNPIYSELGNFNIAGNDPDSRWDFWAKHSDDPVREKEFAHYTYRTTNGSFYVGTEPPAGATPLGIQYPRAGTLGGCAMHNGGVCSLPQDDDWNIVVNMTGDTSWEAPKMRQYLIKVEKNQYLPTGTEGHGFDGWLATAVQPARWARDNKLPATRVLKKMAELTGQNVSDVANLVNKDILGDYPNKDTQTSFYNMAQHEDKGGKRSSPNNYIKATLKDPKNYPLTVRLNTLATRVLFDQASNSTKRAAGAATAALPVAHGVEIMSGPSLYGADPRHTNANVTKKGPVSKVWARREVIVSGGAFNSPQILKLSGVGPADELTKLKIPVVKDLPGVGERLADNYEGSLLAVGQQPVGGGVITLMFKTPNADGPNRNIFTWCGAFSFEGFWPGFPTDYGPNEYECAMVHINPHSQAGTVKLASADPQVPPDINFNFFLNNGTEDLQHLADAANLLRKAWQAAGDPVLPFDEHHPCPGTGAGNCTDEAERALLKTQAYSHHASSSCAIGSDTDPLAVLDSKFRVRGVQGLRVVDASAFPRVPGAFPVLPTIMLSAKAAEDILADAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT45</accession>
    <name>A0ABR3YT45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046422896" description="Extracellular membrane protein CFEM domain-containing protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="37365" checksum="FE7ECF1456FBDE3E" modified="2025-10-08" version="1">MPSLSRGTTTGALLSIYLSFFLARPSFASTIGLPSEIVVFVPSCATACLSTFIDTNYPQGVCGTDPTFACLCAHTGSNGFTVGEGALACIASLDRTGQCTGTDVAATASQKAYSMCVGQSSAAAETHATIVATQVIPFQSQSTKTVTTTAAGNGAGDTNGSTDGSHTTEHTTARVTTSSSTSTSPHTSTTSTTSTRSPTYLTESTLITAPPRSSTTIAALPQTTSTSTSTKSASDTSSAQTGASPNQTQTQPNNKGVTSLSVGQIVGISVGTAAALFLAIAISLYLRVVRRRRLMLVPRLTGDSKQGQSHDSDEEGFRKRFRPRTGHELQISVPMNLQAPARARTSNKHTSRDSSRASTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTG2</accession>
    <name>A0ABR3YTG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CCR4-NOT regulatory complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CAF16</name>
        <name evidence="5" type="ORF">Sste5346_007713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158:SF2">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="19"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="337" mass="37009" checksum="12513DFA9C655C3D" modified="2025-10-08" version="1">MADTQPSDGASASTTEPVIQTKGLTYSFPDYSTGISDITLDLPAGSRTLLIGANGAGKTTLLRLLAGKRLAPKESIRIQGVDPFSRGLEGVTYLGLEWVLNPVVRRDIGVDELLASVGGDAYPARRDELVSVLDIDTSWRMHAVSDGERRRVQLAMGLVRPWRVLLLDEITVDLDVWTRAQFLGWLRQECERHPDRDAGLPPPTIVYATHILDHLAGWPTHLVHMHMGTVREWGPASQFLDDPTYIQKRLAQQRAGEAKEVDGRHTGKNSPALSMLGASGNSRLGDLVLAWLREDLRDRGPRSQNKRGPEGLSYLVQGIGGYGLEVWSKDDGVPKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ9</accession>
    <name>A0ABR3YUQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AMP-binding enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF30">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="61"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="573"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="74771" checksum="CF3870008B719530" modified="2025-10-08" version="1">MQERIIRTATSCPRLLPRLYSSAPAAAAPSVSSSSVPLSLSHGPTDSPRLLTQTIPEQFADIVARYPDRPAVIGRAPCAAAGVTDIAPPRETVYTFSELDRVSDHLARGLVSSAKVKKGDRVAVSLGNGPEFAALTYALFKLGAVLVPLNPAFTVKQVASALCHLGVEVLIMGAVTDLPYKPGRGRSNLSLLSTLVGGDDALTTQKAGAIQSKEVPTLRTVVVVDNTADHPAVAGAGDFARPEDRLAALTPFLDITGGVDILKADQVAALEKKPLVLETPLKASDTINIQFTSGTTSQPKAAQLSHTAILNNGYFIGQRMELTSKDLIVCPPPLFHCFGSVLGYMATATSGAAILFPSPAFDPAASLQMTADHRATGLYGVATMFVAMLELLEHEHGGGEAAARSPILSRERAAALPTHLRTGIAAGSSVPESLMRRLFDTLGLNDLVICYGMTETAPVSCMTTRHDPFEKRTGTVGRVMPHTSVKIVDPEDWSRVVPRGQPGELATSGYLVMAGYYGDKQKTDEVLTVDSATGERWMHSGDEAVMDENGYVAVTGRIKDLIIRGGENIHPLEIENCLFQHPLVAEVSVVGIPDKRHGESVGAFVVPHGGVRVVDGHIAEGEAKTTIQRADATSDPNLTLSPESIRKWVRDHLSPHLAPKHIIWTTSYPKTASGKIQKFKLRDMAKELLVEETEAEGGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX5</accession>
    <name>A0ABR3YUX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055560">
        <property type="entry name" value="DUF7136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23584">
        <property type="entry name" value="DUF7136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7136" evidence="1">
        <location>
            <begin position="31"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="316" mass="32818" checksum="0242B62AFAC62430" modified="2025-10-08" version="1">MAFHWSAPSRAIAVAPILTQTNSMAAADNNFPQYINISLIFPRNETYDSTSGILPVIFSLTNKANAINLYPNISVNISRSSGEGNNTQLQTKLFLDNPQQLSPNSIGLITTSGDNVYLYTPLLAMLGYEGTFHVDYSVSLATMVASNDTRGFVSAVDTPASYGSFGFTLKKGAGASLADLIAGTANTSCANVPFAWPVSVVGIENEGCKLHVNRVPGVTCAYLDSTTLGVVADYDEGKPFVNMTTTAFGCAPTMDAAAVATVVSGIWNASCIHSGNITCPANIPGAPHSNLATVSVPGFAAAMAVVLGAMAGAMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM5</accession>
    <name>A0ABR3YVM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Gluconokinase</fullName>
            <ecNumber evidence="3 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007431</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate acid metabolism; D-gluconate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="3 9"/>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442:SF3">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="25785" checksum="C3170CF8D069BE70" modified="2025-10-08" version="1">MLSSYNSPVAVGPTSPKLAANSAPAPTTASVLSNGVNGVNGINGVNGVTATAKHNNDGSNCHIWLVTGPAGCGKSTVALHLANSLNLPYVEGDEFHPAANIEKMRNGIPLTDADRWDWLTALREESMRQIASGRHEVVMTCSALKRKYRDVIRVAPYFNTGVSLHFIYLSADPEVLHARVAGRKDHYMGPGMVQSQLDILEPPQADETDVICFDVDRPQDDVKAAVLQKVTSIIREEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVR2</accession>
    <name>A0ABR3YVR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006988</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="520"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="183"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="621" mass="66954" checksum="22467D61E04181F7" modified="2025-10-08" version="1">MSEARGPASLASDDTATAPHTSTIETPAATATTTTAESAEKVEAAETASSAPSSALGKETDAEKETHEKDAAAAARREHELEQQAVDEGHDADIPSSKGYILDERGEAKRRKSIADRSRPTTAKSGAAKDTASAVDADVEKSAAGGDAADDFDAPDDPNVVWWDGPDDPANPYNWPTWHKALNCVLISALTFITPLASSIFAPGVPALMAEFKSDSNELAAFVVSVYVLGFAFGPLLIAPMSEIYGRNIVYHVCNVCFIAFVVGCALAPSLNTLIAFRFLSGVFGSCPLTNGGGSIADMVSQEHRGAAMASFAVGPLLGPIIGPVAGGFLASAKGWRWVFWLIVIIAGFLSVVFFFSMRETYAPLLLERKTRRLRKETGNQQLRSKLDAGLTSKDYFKRGIFRPLKMLAFSPINLIFALYMAVVYGYLYLMFTSVTEVFETTYGFGTNTVGLVYLGLGVGSMAGMVFFSAMSDRYIKKMAAKEGQGMKPEYRLQMLPLGAVLLPIGFFIYGWTAEYHKHWIAPIIGMVVIGFANLVIFMSLQLYLVDAFTVYAASSLAANTVVRSIAGAVLPLAGLQMYDKLGLGWGNSLLGFIALALVPAPFFIQKYGEYLRKRFEIKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWC8</accession>
    <name>A0ABR3YWC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF15">
        <property type="entry name" value="LIPID TRANSPORTER ATNI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="316"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="43337" checksum="734C02DADE4D8229" modified="2025-10-08" version="1">MPSSLAPSSTIASSSPSSTSSSADASCTTAVPGKYGYVPADACNSLYNFNPAFAPAVATAVLFGLLTLTHIVQAVLYKKRYAWVIIMAGIWETVAFVLHALGAHDQQNSGYATAYTILFLLAPLWINGFVYMTFARTVYCYEPNHTVWKVKAVGMSKYFVWADVATFIVQAIGGVMAVPTASANVVKTGIDIYMAGLGCQEFFILIFIGLMIVFHRDCLRLEREGALERHPSILRGWRGMLYTLYVVLFLISFRLFYRIAEFGGGVKPSNPVPFHEVYGYLLDALPMGACLLFLALMHPGRLLRGPYSDLPHIPRKERKAAKQAAKQAKKGEKAQRKVDKQQLGTGKGHIEMQQILPSGDNSSAEYNPVSNTEYNNTAYNPHGNTAYDPLRSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWL9</accession>
    <name>A0ABR3YWL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">img2</name>
        <name evidence="8" type="ORF">Sste5346_007132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="141" mass="15444" checksum="461DCDC42D51D938" modified="2025-10-08" version="1">MSTSLAASSRAFVRCAHFRPATAQPMLQRMFLSTTPAASATATATTTTTTSSSTSIADRTPLPYRIGRSNSLNYPVYHRIKSGGTNRTTELKKVEGDAKALAQHLATDLKLETKVNPRTNFVIVKGFHRETLVKWLTEKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXB0</accession>
    <name>A0ABR3YXB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_007010</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="501" mass="53702" checksum="C3755465B85B3F8F" modified="2025-10-08" version="1">MDTYKANLTGLVGLCAALYAGQQFWQSPAEQDTTKESDKSERDSKNAADSAKQQKKTLRAKRAREGREAAAAAHAARASDFLAVYALVMAADWLQGPFLYSLYTDEHHVAPARVPLLFATGFVAGGVSASVVGGMADRHGRKRACLVFCATYAASCLLTVSSAFLPLLLLGRILGGISTSLLFSVFESWMVTDFWENEKYGSSHITSGIDGDDDSDTDDKKEKDEAERQAAARLSHTFGRMGTLNSMAAIASGVFSEWVVSATGTRKAPFVASAVLLGVAAWRIAAAWGENYGEAATKDQADGGGRVWAVLRDPAVLVLGLASTLFEGSMYLFVFFWTPALKEAAESAAPLPYGIIFASFMAAAMAATLAFNIVTAQMQLMRCVTLLLGLLGAAEVVFYLLSSSTSTTLSEQSVFWLFCLFEACVGTYWPCMGFLKGQLVPDGARAQVYSLLRVPLNVFVVAALLLTRDGSYEAVFGVCSTLLLVAIMGVFAMMMNEPNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYN8</accession>
    <name>A0ABR3YYN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="489" mass="54580" checksum="79BFAE190F1C98C3" modified="2025-10-08" version="1">MPPRVSRWGQYLRQRLRRVGNNVVPLQTRPADADSDSDSDPGLPFLAESSASRVSLTDVPVTEDANAHNPFFSRLPPEIRHQILMEAFGGRTLHMDVRLSPPMLPVSKREPSVIAPFELPHGGIGADLDRFSGWPVEVLKAAVEARVITPIDINGDDKHSVSPWQWWSCVCHRGMPHAVSTTSLCEDQCVHGSNTYCGFYAGKAPGKCLVGCTGWLLACRQAYAEGIQVLYGTNTINLQREILTDAILRSTDLSSGSTIPPAIVPTAHLARITRLEIAWDLSLATQPFHDDKQAAARASLVERLAHLARSDAFPRLAHLVLAFGDSLYQRPTPPATCLEDLDKGLLDPLRAMTAEFWKSRQAKVEKRKGGSRNQDAPILQLTVELPTNTFNPLYERTVRCGGVYEQGQSYYQRRFWRVSIVKVDEDGMPAENQEEKEYEKKEGDEDDENTDKRHKIVDCGFWVKAGIESRLNFDYQGNPYRLGTVATLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZH5</accession>
    <name>A0ABR3YZH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12418">
        <property type="entry name" value="RRM_Aly_REF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF82">
        <property type="entry name" value="THO COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="108"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="369" mass="40247" checksum="320DBB4F9C3B614B" modified="2025-10-08" version="1">MTANMDVSLDEILAERKSERRGNRGRGDRNNDRGDRGDRNDRNGGRGGGRRDRDRRDDYPRDGVRKSYRDEPRKIDEEWVHDRYDNNDSDHHVKSSRSRASPERPRGTRVRVDNLHYDLTKDDLEGLFNRIGPVASVDLVYDRAGRSEGTAYVTYHEHDDARTALREYDGANAKGQPIRLSIVPAGGRGGRGGNTTLGSGRPLADRISRPRKRGDDGDEDEGDEDDGRTSLAMAARRGIDRYVPGSGSTRGNGNDNSGRLSRSRSPAPRRRDGGGGRRPGERRGGRNGRGDRNDNRNDNRNGGDGGRRPRKTQEELDAEMADYFVEGSNGNGAVAGEASAASAAAPVEAAPAAAGTAPADDGDDTDMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0E0</accession>
    <name>A0ABR3Z0E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006679</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="16"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="446" mass="48798" checksum="CB6C78C2AC681B6A" modified="2025-10-08" version="1">MDNFERQLAKATDPATRELVGALAIVVDDEGKVLYQHAAGRQSLAEDAPPLDPDSTVSLGSAGKIITHIAALQLVERGVLNLDESVIKYLPELGRCLLMTGFDEDDLRTPLFRRPASPITLRHLLLHTSGLSDHDAVDARFGWDAADRATAGVFDHDAHPIAQRFAIPLIFDPGEGFAYGYSIHWTQLLVTRVCEGNSFVKHVQDNIFDPLGMASSSYVPRKAEDLWARRLQMVERRSKREIQRAEAEAKARVESAAAAADGGEKIKRNSWGNPIGDAVEEEEEEAEEGTVLVDAEDQQQGLMCSMSDMGRFLSALLSSSPLLLKDKASYDLLLAGQFAPGSTTLKDLRGEQDNYKFVTGATYSRKEPPPAVNWSMGGLVVEDEPLPVSALPPGTVTWEGMPNVMWAVNREKKRAAFFATQLVPVGDLEANNAALSFIHDAWTTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z143</accession>
    <name>A0ABR3Z143_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="213" mass="22663" checksum="DBAB0D742A7914A0" modified="2025-10-08" version="1">MAKTAIFHREALRSHHFGHEHGLRHPGRHHSLSPLQGLFWSSPASSSSASPSTSTAPPAPPTCNTNLLTNGDFSNNINYWTITGNYAATIDGCGPYSNCMDMYFGSGSVQISQSFDTQAGTLYSISFGYYAAVNAGAAFTCNIIAGDNLENGVTIASFSLALALTTWELYGDVFHAAAGTTKTTVACVVTSDSFTQFELMNLKIAIPCWDGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z189</accession>
    <name>A0ABR3Z189_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="52"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="436" mass="47552" checksum="D51FF30B9E051D07" modified="2025-10-08" version="1">MSTTSSAVAPAATSVAASPFGDPALLPHDSKKPDIIASGVITLFLAGLFVAARFYTRLFITRTRLGASEWLVLSAWIFSFGVTIPQILETGYGMGAHIYDLPEGGFNFSGNAEAQLISIFFYSLSLTFSKFSILALYLIVFPYTWVRSVSFFLLAVVAASQIWMLYVIFSACTPLRAFWDMTIVGATCHPQAYWLANQYQLIATDFMIFLLPLPVVWRLKVKPGQKILLVFVFAMGFFVCAISIIRISLIIPLTNNPGPDFSYSGVATYYWTDVETNLAIVVASSITLKPFVSMLLPKSLFGSPDDDFGGGHQLEQVRRSPNRSLFDPIITFGSRLTGRTGNNATGSRGADSGLGISDDTKALRSAPSSHASHGSSSRLDNYSQSTSGNRTILDHHGNAVDEEMGLPQHDDNSSSEPKPQLQHAVRSTPSDQTLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2B4</accession>
    <name>A0ABR3Z2B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VCX1_2</name>
        <name evidence="10" type="ORF">Sste5346_005843</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="631"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="480"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="109"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="653" mass="68710" checksum="4A3983BF6EA8D250" modified="2025-10-08" version="1">MSKKTPILPLTRTDSTPSPRSPRPRSILLSPSPRRVIIVTPSTDEGGDNKNKQGSGGSSSRYGEGDDYFGSGIGRHGVGGHGGGSGSDSGPALMTPALTLSTTWASPSVGLLRPMSPSRPPTASPGISPLGSPRSSPRIPTTPLAAPLLEGSRQTMHRTMSMSLSMSRSMAQLQLPSPPSSPPSPQPASPVPQPTLLKVPTTVAESDTVDNSDVEATPLARTSRVASVTSIASIASNVDWGWFRSDMFSVLVIMVPLGLAAGICGWAPKTVFTLCAVSLAGLEVFVNTTLERIGIAAVYADATMLAKSFVIGYVLNNILLGTGAALFAGGINLSSPQTSYCQDVSESALDLIKLTLIATGPVMMTWAMIYVTTVQAQGEPPAIATEGIVSLSRGTAVILLVLYLSWVVFRRVTHRADFADDDRGRRVAAELVREAYAAPSKKRRQDNIEATAGQVVDTTKKKRVFDSLPTPAACVVVTTAVLVALASAVVCSYYLVQSIEPLVRSTYEGAAASPSPSTPSSPSTSPSAPEATAGTLKGHFVASIVLPLIVNVYNFMRAAEIASCGGRDVSLAVHMTYGAGANTILLTLPLLVLVGWWSGHTLNLDFQSFDVSILAGSVWLTSILVTDQVDYFRGFILLCLYVMLALAIFLYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2U0</accession>
    <name>A0ABR3Z2U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF133">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="308" mass="32281" checksum="86268D5364DBDAA1" modified="2025-10-08" version="1">MLYNTSPDQLYEPRTTVVNPVGYGKVALVTGCASGIGLACTQLLLEHQFSVCGVDRSPFDYNLLRVADHGRFHFHLADLVKDVGACDEAVRICLQAAERDDRPRRVDLLVNVAGVLDNFASADTVTDSLWDHVLAVNLTVPVRMMRAVLAPMKEQAANKTTGNGQGGVIINVASTAAVSGAVAGIAYTASKHGLVGATKNVAWRFRNEGIRCNAVLPGAVDSSVGQSIANRVDGGLDAGGFTQAEPVLALQAHTQRPDTGSPSSTKSANTGTDITALEVARAILFLASDAANSINGVCLPVDKAWGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3N0</accession>
    <name>A0ABR3Z3N0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">WD repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="327"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="369"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="681"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="772"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="772"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="793"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="809" mass="87843" checksum="A1A565819DE1979F" modified="2025-10-08" version="1">MAENNSSPSAVSPVLVTSHDSNALLMSSPPRMTTSSFVDAAAVGGSKERRQPSITPRKFRRFFTPRSRVSADPSAARRALRDLTARALNRNQSPGPFVGSSSPFNFSSSPLAARVADSNKNDCCVDVLPSPRTTKRRKTGHHTPETSPLRSSSVFHDAVTTPEPVSKTAMASMLLSPLASSPLPAIPDEPESECDEDNFSMSDDEPELPFSGPSFKRTIPLSERGFAGQLLQREYGMASGPGRRTLPRPLGDWRVETSDFYSSQDDLHYCSSHDVPNSRCIPFCAAACNTNGLVAVGDEEGRIRLLDTTAENYGTSSSSFSDIYLSFPAHGNAVIDLAFSADDYLLATASGDQTGKVIDMMTQTPISILDHHTASLKQVRFQPGRGEGNVLATSGRDGSVKIWDLRCRGGPAQEFTVEERTQGLQYAPPKKVNQGCVVNSIFDAHARTTRPTRQMRKAMQAAVAADVTTRWEEPGRVGEVSVTAIQFLPAGKEHLLLSACEADASIKLWDIRSVHTSRQKASNPISATAPPESHSQWRPFGMSSMSLSTDGARLYGLCKDNTVYAYSTSHLVLGSAPELSSKGNDHPRRRNGIVQEGLGPLYGFRHEKLHATSFYVKTAVRPAKNSNPELLAVGSSDGCALLFPTDERYFMGAAADQYNDDHRNPVFGQDNSASAPIFTSPFSRGGSLPRPMAAENDTSTAPRRPGLFRTNSMSSMHGRLVDTIPIVRNGTALVRGHENKEVGAVCWTHNGSLVSVGDDNIIRCWREDQEKAGALRSGGEGEGRRWASGWAEMGEDWDDEVDEWGEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z472</accession>
    <name>A0ABR3Z472_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Subtilisin-like serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046536">
        <property type="entry name" value="DUF6601"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414:SF1">
        <property type="entry name" value="SUBTILISIN-LIKE SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20246">
        <property type="entry name" value="DUF6601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="41223" checksum="CEB664275304999E" modified="2025-10-08" version="1">MNQQILPTWPFSTEVLDHVDGTLDTLPAAYHCYEYIGGEKKNRIVVNPANDPPNSVSDFLDSELSLGDLGKIFRYLRFAGSKYPATQLHLQAAMGREITVADRMDLHLLWDNNSKIFFKPIPRFLLDPGFWRRNLMCPGGCACEKSEAAATNGGAGGTPANQEAPAAPCKETPRRVALGFLYTYACLVTSESDFFVANDKRLLPRQAEDKTIEWATWKELVRELLETHDPDMVHPRFLRSELRLSRINTISRFTSLPSFDPYLRGWRNYGSFFRDNLAWMATAAVFIALVLTAMQVGLATERLQSNADFQRASYGFTIFAILGPMCAFGLAALGALLNLVKDLPWLVGDKAAQPRGAPAVSAKDKSPLSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z491</accession>
    <name>A0ABR3Z491_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052567">
        <property type="entry name" value="OP_Dioxygenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202:SF1">
        <property type="entry name" value="HD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="40"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="205" mass="22395" checksum="4CF0E573A4F53F7F" modified="2025-10-08" version="1">MTTDISNIEASTRKVVRTLFSFLDAQGQGDYMGEAVSQLQHSLQAAALAVEHNADEPTVLAALLHDVGRFIPEAASLPKLIAPDGSAFGTEEHEKVGEQYLQRLGFPPAVYEVVGAHVWAKRYLCATEPEYWASLSKLSKVTLELQGGTFTPSEAEAARSDPLLESKLNVRRWDDLAKEAGKVVPGLDAYEDMAVRILEEARANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4E3</accession>
    <name>A0ABR3Z4E3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial oxaloacetate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OAC1</name>
        <name evidence="12" type="ORF">Sste5346_005602</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="2"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="107"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="208"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="308" mass="33714" checksum="4085FABB8BC55DF5" modified="2025-10-08" version="1">MSTTAGAFIAGGIAACGAVTATHPFETVKIRMQLQGELQAKGHQPHHYRGPLHGVSVIVRGEGLRGIYRGLSCAYIYQVLLNGCRLGFYEPMRQGVTGLLYGNNAVQSLPINMFCGAGSGIIGAAAGSPFFLVKTRLQSYSPLLPVGTQHEYRNAWDGMKQIYKSEGLRGLYRGVGAACIRTGFGSSVQLPTYFFAKRRLQRHLGVKEGPALHLASSTASGFVVCVFMHPPDTIMSRMYNQNGNLYKGVFDCLAKTVKTEGFLAIYKGFLPHLARILPHTILTLSLAEQTNKLMRKVENRWFLKEAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4X9</accession>
    <name>A0ABR3Z4X9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF201">
        <property type="entry name" value="MFS AFLATOXIN EFFLUX PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="64"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="586"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="594"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="656" mass="69632" checksum="57FA34C9B69F07FB" modified="2025-10-08" version="1">MFSKKDRQPLPSADGTAPPQPVTTTVTQPATTEAKSATDSQPLQRTQTAATENDHPHGLKLLSVMVAIFLAIFCVAIDRTIIATAIPKITVEFDSLQDIGWYGSSYLLTAASFQLSFGRMYAEFSIKWVFLAALLLFEVGSILCAAAPNSPALIVGRAIAGLGSAGIASGGLTIIGRVLPLHRRPMFTGAMGAAMGISQVIGPTIGGAFADHVSWRWCFWINLPIAGVAIPVVVFFLNVPKLPPPPTAAGAPAPVPLKEMTIPQILRRFDLVGTILIIPSIVSLLLALEWAGTTYAWNSWRIILLLVVFAVCFAGWATVQFLAGDAATLPLRMIKQRSLAAAMVYMFFVMGFMYPLTYYIPVWFQAVKDVSAQQSGVNILAMTVPTAICAVTAGFLTSAMGYYNPLMLTNTVLGSLACGLITRFTVDTSTGYWIGSLVVFGIGLGFGGQQALMVPQTVLKGRDIALGTSAMIFWQTISGTIFLSVAQNLFADHLVDELQKRAPGVDAQFVVASGASDVQATMSKVYSPAQVTEIVASYAAALQKVFLLSLILACLTVLGSASLEWKNVNKGKKAAAAAKAAAEAAAKGETPAADTKDVEAAPADNKETTTIDDGEETELNDLHSHSHSHTNTLREEEATVTLEANAGAALPTDRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z595</accession>
    <name>A0ABR3Z595_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF110">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="72"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="251" mass="27796" checksum="F0F6FC756011388D" modified="2025-10-08" version="1">MADTTERVRADPTDTVPENLKARIKASYDAIAPVYNKWTIDHSPVRIEYLDQVLIKLRPKGQAAADKKPLRILELGCGAGRPVTEKLLVELDPVHVTANDISTGQLDMARDALGEHGEKVAPSANSRVDWVEGDMMALDFPENSLDAVVGFYSVIHLPGPEQATLLGRIGKWLKPGTGYFLANFSDRVMPGMVHEKWLKQDEGWMFWSGLGVPQTEAAVAGEGKLKLEVSKLEKDDVDDVDFHWVIARKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5M2</accession>
    <name>A0ABR3Z5M2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF63">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="150"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="462" mass="51477" checksum="045697EA94F6556C" modified="2025-10-08" version="1">MDMRTMIRQGQYRQLMIVAAAGIILLLFYHLYGKVAVDDVRLRAIAAKGGFTPDRRLFDSLHLDEKQCRVTFPDITKDIDNMVAQGTFRVLPKPVDSDSSPLQVRLQNGRLYIVHHEGKGTLDKGFVDARMAALHQLHRAVLTAPSTDPLLPDTVLAINVLDGPANDTLSYSRPAYAASTPGSLPVTRAFLMPHFSFWGWPALPFVGSFSKAAEAVAALERQLPFSQKDPRPVWRGTKRYNSAQHPQMRTDLLKVAGTASWADVQELVWEDRGADRENSDPVAVNALRIEDFCRYKYVLHTEGITYSGRLQFLQMCNSVLLTPPMAWLQHTSHLVKPLFSSYLLPDNGGKSPSWMPSDGVQSAWPVHYTANEANAVFVAPDWSDLQATVAWLERHPDVAQGIARRQQALFVDGGYFSPAAETCYWRALVRGWSTVAQTVGPAWVGEPRGVPWEVFAMGYESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z622</accession>
    <name>A0ABR3Z622_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="43699" checksum="2BEB098BFB74E882" modified="2025-10-08" version="1">MEIVMDGVAQQRAPRPKVKTGCATCRESRKGMGKAAPSKTVTPAMPLLLDETSLESTSITDTDIADLQRCFSTKTLFPTVTLACADEARQVLQASQTDPAVRHAVFSLRALRADLEATAKYGGGGQSNQPTHLSYAASSYAAATGTTPNRDYGLQQYCMALGGLASHLSTSPSTTNTAPAPSVRTALLCCQVFISIEQVRGHFAAMAQHIVQGLRILYEHRGRDQDLPAIDVFIIKLFAAPCKFADVTRGVPSSAGSTPASTTGSEGGTSCRFRPLAPDLRSELTRHAMSTVSFLASVKAGPPTQSLQSTKELLLQSLTTWYTSLEREKQTTERPQPELLSILFLRFFHQILRVVLLSALDSDGQEDKDRQSEIMDTEYKQLQRIASFVGEQVHADGLKSGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z626</accession>
    <name>A0ABR3Z626_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="7"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="59778" checksum="CE73768ECD0E6308" modified="2025-10-08" version="1">MAPLLPVRVSTGLLQGSLSEYDDSIAVYKGIPYAASTAGENRWRAPQPRASWEGVRHADSYGPPCPQVPFGPMNILPTQDEDCLSLNIWTPAKTATDAASSEGTPLPVFVWIYGGRFIAGSGSELAYEGTGLASKGVVVVTLNYRVGILGFLSHPELDAESGHSASGNYGILDQIAALKWVKENISAFGGDPSSVTIGGQSAGGASTGIHVLSPLSHGLFHRAIPQSGQRYPRDPLLSGLAPAYRSKEKATRQGIATVAEKGAASIADLRKLPLDILLQGNNKNDDVWGNPPFYRPCIDGWVLPATFEECLRRGIQADVPILTGHNADEGGTYADPEFNEDDLKSCAEQKYGALAGRFLELYPRGNGVDARDAWNQAARDNSCVTTALWAKEFHGQAASPVYGYLYTHAPPARQGGPDAPPSRQAIGAAAPENNAPKLRIYEKAVPRSEYTYSKIGPGARYGAFHGAEIPFVLNNLYAQDGYPYGEADHEVAAVMSSYWANFIKTGNPNGAGLAEFTTITDDTIMRLGRDCYPIPLADSPERIAFWKEHLEAQKPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6G5</accession>
    <name>A0ABR3Z6G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005214</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247709" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="64216" checksum="20C5210ED44BE4B8" modified="2025-10-08" version="1">MAILSKLTAAAAVASFWTPSSALVLRDGNSTAPACMAVPANKTYDYIVIGSGAGGIPMADRLSEAGHSVLLLEKGPVSTGRWGGTMKPKWLQGTNLTRFDVPGLCNQIWHDSVGVACTDLDQMAGCVLGGGTAVNSGLWWKPNPRDWDSNFPDGWKFDDMAEATSTVFSRIPGTIHPSMDGKLYKQQGFEMLGGGLKAAGWQEVVPNDHPDLKNHTYGHSTFMYSGGERGGPLATYLVSAAQRGPDKFAMWPNTMARRLVRTGGHATGVEVECTTLGGGGGGHAGVVQLTPGTGRVIVSAGAFGSAKLLLRSGIGPDDQLNIVQGSAEDGATMISKDSWIDLPVGYNLNDHVGTDIEIAHPDVVFYDYYAAWNTPVVSDEETYLANRTGMLAQAAPNLGPMFWESIRGTDGGIRHLQWQARVEGSTNTSMTITQYLGTGSVSRGRMTITKRLDTFVSTPPYLHDDFDKEAVVRGIENLVKTLTPVANLTWIRPAPNVTVVDYVNSIPAKPAQRCSNHWIGTAKMGLDDGRKGGTAVVDPDTKVYGTDNIFVVDASVFPGHITGNPSAMIVILAEHAAKKILALPSTVKQSVPPKPPTARWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6T4</accession>
    <name>A0ABR3Z6T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004666</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="28"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="487" mass="54526" checksum="1CAF259291F893F9" modified="2025-10-08" version="1">MASRIREYFNTNYRPGERKLVQKIDFFILTFCCVSYFINYLDRSNLTNAYVSGMKEDLGFVGNQLNEINTCFTVGYVIGQVPSNVALHHIKPRFYFPTMMLLWGGLTMVTAAAHKPQAIMAIRFFQGICEASTFVGTHYILGAWYTERELGKRSGIFTSSGLAGTLIGGFIQTGIYKSLNGRHGLAGWRWLFIIDGLLTVPVALYGIFLFPDTPHNTTAFYLSDAERQLARDRVPLQEQAHQAQPKSIKTVLKIARMVLSSPYWWGFVGLWTIAGEVESFSSNGLLSLYMKSHPYVKYTVSQLNNYPSGVPAVGILSTLFWATLTDILGGKRYLVGYWISITGIATSIMILVAAKNPLSSHSSAITFAAYYWAGSVYACQATFFAWCNDAMRYEDALFRGIVLAGMNLGNNAVNAWWSIIFYGASYAPWFNRGMWAMIAVSIAMIIWVTGLVWTTVRLEKRRISQVVVGEDDANRTKSIDINEKPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7F0</accession>
    <name>A0ABR3Z7F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004874</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="304"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="879" mass="96282" checksum="B899DC35C4735C32" modified="2025-10-08" version="1">MATIIAQPAPAPAVVASNERARRPRRQYKCAFCQKVFKRSEHCIRHERTHTNEKPFSCRYCRRSYSRKDLVTRHERTLHAQGQAEPSPLPPTGIPVENDESDCSSSDVGAGSVPGRKRRRIDTAVLGIADDADPPPSESDLPGDNGTTDSVTNAVTNAATDAATDAVTDELRTQSRAPPRQPDVYTGLHFGVYDAASQISMSIDLDQTSRHPDEHSNASERNHTQLDLQQQSQPRQAHELYPFAQYHDTGAQANAINQNLDPRLFAAFEPADMSSFFTLSPFAAGLFDVDQNMPNMVTPGMASYQPLQTNVSPSPSASRPVAGISPTPVPPAHSPYQLQQVEDQVKDHATSNGSNNSAARASPSNLPLLVKDEPPRIPSLAADNDWHASLCKDLAERLEEPNAIQEVPSAKLLQGCLTSFLDCYYRHQPFIHLPTLSVANTPSPLILGMCCIGALYRLDRRRAEKLYTLGTKSIAGDVRAFLESSAELPLWVGQSAMLLTAYAALSGDKALAGSVMESNGFFALLYGKTRVALAAQDPDITKMTWDVWIRRESWKRLLGGIYVASTVHLIIWDTSPYVNTSHDLEIEVLHEESLWNAKTGAEWADLTANQPRQDYRTLKDGLASIMSDSKPDSPRIAACRLSPFTALLLMHAVVVHVWQLVQVAHTLSPPPSGALGRDPVSSLLVNSAFRSLARSHEMLVGAEDPTSASHEEGTSQIFNCHATLRMAYIRLFSVAHGFERPSLLASSDPVVAKAFASQFATTKFERSPQLFNAVVKAFEGLSIPGQSALFVCKWVHSVEMDQLNGIEPSLAENELLENIKEVLEEAEYDPGKSQSLAAGVARTWSWLLQDEVDFCQAELVQGVDDLGDDGLDRVVILVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7V5</accession>
    <name>A0ABR3Z7V5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="549"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="226"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="580"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="409"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="488"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="506"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="611"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="628" mass="69182" checksum="C9DBFF01DBA5EA24" modified="2025-10-08" version="1">MPRPRRVDPPPPSSSTTLSSFAPTSFYSSLTAATTSTSSSHKSKQKQRPNTQLRVLLYDKPIYRTRSDALQPPISLAPPRDDDNAAFIVDKVVTPFDWGGPPAVNTNADLGIDPREDDDDYDTDEEEEKEDERYRQNPERQQIKRVLNYVVGWPDEPYARQLVPCTQILEYVSPRVLEDWEYALTERQRAAREARREEKRAELLAKKKGKLKEEDDVVMGDVLREVAPAPPKKKPGRPTQTAAATAARVAAAAARKEAAAKGLPPPPKTPKKTKPMAMSSMTMAVPTPGGPADRSKRPGSSLSARSSLTGLQIQLDSTPMTVSIGGPPPNPFSSPTSTEKTKAGPSLKRPFQKFVEQQVADDSESRSASLGVETATTNMSAIEEEVADSDGYDQLQRPVIRPPQPPQPHSMSMLPSLRGTPPVQHQPSQRSQPSQSQITSQTLAPTYIPPPDVPHAKQPKQSMTPGPQQPPTTQPPATLKRKRSEETPIPPSATPTTQQPPPPAPLQEQAAADLQQPDPEEEEQDLYEVDQLEGDCMTVVDEGGNPIDENVEDIDLENPPPPPPGSRVARLFLVRWKGDWPPDQNPTWEPAENLPPRMVRQYLKRAAQKQATDDNKSKHEHVEGHARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7W2</accession>
    <name>A0ABR3Z7W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Chromosome condensation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_004701</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="167"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="54540" checksum="8298260F25E7946A" modified="2025-10-08" version="1">MHRHDVEVGQQGDSSAGDNNTASISEVDNNAINKTESYDIPLSYVNLNEAEAPPPAENPDELPVARHRSLEEYREEDEQSRREEQRHPTKKHDRRRYGTAISRPFVELYTISYLIFFSLFGTLARLGLSSLTTYTGAPVTFGVLWANFAGTVVLGFLAELSPVINRDHAAEEEEEPKKEEAPAADADDSIDRDLADADPVDEENEEANNNTVAAPAPPAPTPTPAKRPRPIPLYVGLATGFCGSFTSFSSFMLEVFEALANTLPAPKYHPGDDASEVASRGVGYGFMAPLAVLFLTVGMCLSGLKLGAHLAIFLNRLATRVGSKKWTHSHTTTLLRIADNAVVILSFGAWLAAILITVFQPGPAKSHYWRTDVLFALIFAPPGCLLRFYLSLKLNGTFATFPLGTFTVNIFGTATLAMAWDLQHASAVAATRLVGCQVLQGIMDGFCGCLTTVSTWMAELLGLKRRHAYFYGGMSLAIGLVAMVLIVGTPKWTIGWQEPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z800</accession>
    <name>A0ABR3Z800_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-conjugating enzyme E2 6</fullName>
            <ecNumber evidence="5">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UBC6</name>
        <name evidence="5" type="ORF">Sste5346_005124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="5"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="308" mass="32625" checksum="2D8E95C7DEAA696D" modified="2025-10-08" version="1">MASRAAQKRLTREYKTISENPPPYITARPSDSNILEWHYIITGPEDTPYHGGQYWGTLMFPPDYPFAPPAIRMHTPSGRFQPSTRLCLSISDFHPRSFNPAWEVSTILIGLLSFMTSEEMTTGSVSATPAERKFHAARSRWWNSTGGGTWTGTDTKAKVQVKAGDGGLKFRTEWPDLDKENWAWMKEQNVDLATGVAAPPQPKAQPSSSTASSSATSSSSKTITGGGAGGSASCGKQLGVPAAGTGGGAGNGAAGGNSGTQAQAVVDAVRQGRGAGQGWLARNKLYVFGGLVFLYVLVARIVGGDKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z806</accession>
    <name>A0ABR3Z806_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N,N-dimethylformamidase beta subunit-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046540">
        <property type="entry name" value="DMFA2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20254">
        <property type="entry name" value="DMFA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N,N-dimethylformamidase beta subunit-like C-terminal" evidence="1">
        <location>
            <begin position="288"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="754" mass="81327" checksum="BA8E6B35367A0D72" modified="2025-10-08" version="1">MSTIYEVPKDYPAEIIGYAEPWTVSPGDTVAIKLSSTAPEYTYRTVRIIQGVDVPNSPKKEEEEITDIPPGTGTGRFQKALPGSYGLVSKSLPFPEDAVGVNISFFFQAWMPQCDHVQTLLSTINTDRDRTSGVAAVISTEGTLAFWVGTSTSVEVVDSGFKPPRKGWVGVSATMQGSELTASVWQVSLLSGPDKKTNEKTFTYSLTGSVCLKDLGALMVGAGHGSSGQPVHFFNGRMDRPRIEALSSAQGTLPSLLIDLDFSQQIPSDAIIDVSSNGLDGVLVNAPTRAVRGHDWDGTEPNWTKATYGYGAIHFHEDDLDDASWATDFEIAVPSSARSGAYAVVVTAADGSTSDSVPFFVRPAKDTLREGKVAVVLSTFTYLAYANEHLWEKSRSSAIDVGPGFDMANIALSDDFSRLQRRDDLGLSCYDVHRDGSGVVYSSCRRPILNIRPGYIMWAFKRPREFSADTMLIGLLERENIPYEVLTDHDLDACGVDILHGYNTVLTGSHPEYPSPAVYGAYLDYARQCGNLMYLGGNGFYWVVGADSQVTPHRIEVRRGDQGVRTYTLSGGEHALSTMGQQGALWRTRGIACNVLFGVGFAGEGVAPGVPYKRVPKTSNEKSGMEWIFDGLGEDELIGVDGLGGGASGDEVDRFDAELGSPADAIVLATSTGHSDEYGIVPEDLTFPVDGILGTQTDRIRSDMVFLRTPAGGGVFSVGSINWCCSVGWNDYDNSAARVTLNVVRGFLSKKNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S3</accession>
    <name>A0ABR3Z8S3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytoskeleton organization protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1027" mass="112884" checksum="0ADD5F06AA5A5306" modified="2025-10-08" version="1">MSHYARQRPPLKNGVDMQLQAAFANQNWTTVIQLADKRHKASKDPYFEVVKVCAETRLDGVTEKASAAVLVDSWVHNNTIPQDLDSIELLEWATDAENDDYKYGETFGVLRARWVKVNPRNVAAATASLRMCLQAWDLTNAQQIATILDKSSHTHDRRYTFWGILLTHLLSKDTAQAESKRKIYGMLAQKQLEKAAEPAEAAETTAKITDNTTNISETDRSLHTEEEFLLYLRVLAEHGTADNYAQRALHKTAGAAAQLAAAGRKQLFYEVLERLETLKRWDSVFDLCREALSLTTSVDQPSTLACDVRIWNSFVTAAQKSDNPETAFDTVQSLLTRFIGATSPKLPQMYTKNVGLALLQTTFGLPPALLPEPAEGQSSLQVEQLLAFIEANLDKASLFNDVRSFVERLSFNQAQDLLTRLEVPSTTLRRVLVLKLRYLLATCPETRCPRSILYNQTEAEADQALLKGDGGPSLFELACKVCRNAAPESYGCTHCLQELAKSSLQLHHSLSDDSEFLSAVPKMDKDPRIDLALVAASSLLRLAGDGSDTKSRPLLQAALVLDAQQRQTPDDIPLRLLMVRVFLRLSCGSHAQQLWQPLGVKRSILDALGPLFYDRLSTVAPGLFAGASTPKKPLLLEPLKQYFATVLRHPSAVRIWDAFASGSYSSILDMATYQVRLQRSCTRAMTVVEERRAARALGGRLDDSLLEDVSTDIPNGERLHNATDYGALPNLESSFGAHLVERVSLGPGFSNTRMQLSLLAERYLEVIMFKPPKEYKPAKAGEATARDKAFVVESLARIQFAFDDLLHGQPDPTTQLTPAELAYYTAVSVLVSFAAFSLNSTTGDTAPTPSSIFALLNQSLTTTVDLLRKAALPPVSSSPTTSTLLHTFTDIHSLGILRETAVAIKQTGTFLAAFHDKENARDRTGKSGLGKEAVASAASFKTLSTRLFTDIKAHVKTTKDTLGSSGWLDRLGETVTKPGESEGQGQKELAGAIVAAVGGSSAVEYWAGRLLDDWRETIRGWGQVQME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8T1</accession>
    <name>A0ABR3Z8T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004524</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF9">
        <property type="entry name" value="TRANSCRIPTION FACTOR GRISEA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01119">
        <property type="entry name" value="COPPER_FIST_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="270"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="460"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="570"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="646" mass="67164" checksum="B0E99FFE69E52691" modified="2025-10-08" version="1">MPMINGVKMACEPCIRGHRSTKCNHASERVMLPVRKPGRPLSICPHPPNNGCACATVTAALPRAKKCGCGSKSSSAAGVNGASGNGSAANSSKTPRSPSRRAFFKAPTSPKSLARSRIDPSVLGRTDMSQVNIRAPPPGTSGWPTNEHPQSSIDDLSSLAGPGHPNGQQYMLPNESLAYFSNQGEQSAMFQQPGAPGAYAQHGYPIQHDPASEHAMYATNGGHNDFNEFFNNGMDMSAPLGEGLDGFGLNLNARPNQMNGFHGLQFQTSHAAPPQVSAPAPSPAVATTKGSCCAPATQPQHLATESARHTPTSSTNSLASNGGGSGSGTTATSNSNGKSCCSGSPVTASSASSQQQQQHTMLKSESSIGGGPGPVSLSSVPLAATAGGDVKPMANGHGHVDQYGTLQQQPQLGQYAGYAQQQQQAHGAPTWYRYPPEYGTVTAPLQPSQWRSSLITAGPDAGLYLQGGHQQQQQPHQQHQQQQQSQSYDPAALQHQQPPPHFAVQGNDMVPSDDDLHMCSCGDGCDCVGCVAHPFNNATRDTVRSVWSLMDDSSSNASASSGARTVTTTLPAQTSNVDSTSSPQQVFTPAGASDTSGVSEDQQVSLPAGDFLFVSYSVIACDGEGLMCPCGDDCQCVGCTIHNNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z978</accession>
    <name>A0ABR3Z978_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004364</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="253"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="488"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="586"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="588"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="796" mass="87079" checksum="A7B68B33E6D1EA73" modified="2025-10-08" version="1">MTGMTGMTAMAVTVTIVTVTVMAVMAVTTCTILTNCHRPQRPRLCRLRRRSHRSASPPAEESTTSTKTRYISQGHWMNGALLTIMKPLLNEILGKKENKSGELYQNMKKCKSLGRVIKSRRVPAMLAIDYGKQVPAREVADELINSYFRTFETVYRVLHIPTFTQDYRRYWENPNAASTNFVVQMQLCMAIGTAFYDETCSLRHLAAQWIYEAQFWLMTPAPSQKARMNIPSLQTMCLLHLAREVSGIGADLVWISAGELVRSAMYMGLHRDPTKIPKIPRYLAEVRRRLWATILEISLQSSLDSGGPPLLSLSDFDTLPPANFFDDQLVEKTTTTSSGATPPPPKPLTTFTNTSIQIALLKSFPIRLAIARYVNDFRSGSSYDETLRLNSELRTACQSLAGTIQSYRPSGSAGKLRPTNFQLRFVDHLTHRFFLSLNQAYLAASQNDPKFYFSRKVSVDTSLKLYQAWSGKASSSLSANFSSTPATGPLSTLLRGQGTSSLPSPWAVAGSGPPPPMTSSPATGTRDPTSTADGLEDEQDDFFRLSVSASSGFRSVPVQCMATLSMDLLWQLEEEHSVRLRLGIKSANGTSNNSSGNNNGSTVDGDHGGSSNNAGDAPTVRAASPPPDAGSMLAMPGVVTQAVLLEALEQTVRYSEKRLLAGETNVKGYLFPCAVVSQARALTRGADAEDMEHAVLNECTDKLKHCVDLLREVASLQSGKPIDDDAITSMSLGSDLTMNTSDNDSAALPDMNATLPMGDDLMMGTGNEWGWEDLMQNQGFNFSFNMNGLDTFFAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9K8</accession>
    <name>A0ABR3Z9K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="281" mass="31667" checksum="1891673AD19DD287" modified="2025-10-08" version="1">MHDMEDTNSGHTRGLMRPIGWLAGTTKHHNALIRALNNVLTTDLARRTLGQIVDSFVLYGAFFGDTRAAYGQCSELNADVLLKRGQSRAKVDIRTLRVDAAVLSEFCEAEIDSTIFQQKLIELVARAVHAMAIVLYQKVPDTTWRPDFHPWYSDSQSFPDGEADGVGYWAEDRILGGVVLFDRRDRDEVPNTALEYKNDAVYFHPSAEGTSPRIYQLKDSQRQALLDYLFGAATPSAPEPPATFLPIRCDSDNSISVDPMETTSIYRDKWERLLTRHEQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9R1</accession>
    <name>A0ABR3Z9R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="77"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="154"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="295" mass="32438" checksum="2CD8F3E56F11611C" modified="2025-10-08" version="1">MPFYQRAFFNPAAADNAFTNIFQLINDIDSYQREASPAATPACKPQPAQAQPQRVCKPRHEHHHRRSVGGLNGLFGGVSRPFNPRFDVRETEHTYELHGELAGVDRNNVNLEFTEPQTLVISGNVERNYSTASPAAVAAPAATAVPEAIADTHSEFDEDNILPDGARTPADEDEPFTEIDAPRSPSPARSHRATVTDEATEDALERGEDVTNEKAAAEVADPAESVPEEAETAPQQPAAPTERYWFQERAVGEFKRVFNFPVPVDEASVRASLENGILNVSIPKAKRETRRIVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9S8</accession>
    <name>A0ABR3Z9S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004453</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="3"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="156"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="244" mass="27702" checksum="F3CC12F6A20123C5" modified="2025-10-08" version="1">MTAFYVDEMLYLVILTLIKLSLLFLYLRLFAPQATPTTHEARQYRQHYCNFRITVFVIAAFVIFLGIIFLFLDAFQCQPVDTVWTRWTSTSLIKDDPFTCLNVHLLAYVAASFGIAQDAAILIAPWPLLFLLRKSLVRPSSMPSSSTFASTASRLTTAAMVTALAMFSLGIFVVATSCIRLHFLANFDETSLNPTWDNTDSLIWSGLEVSVSVIVMSLPTVRVMAQQSWLSWRERSMLWSSNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Z6</accession>
    <name>A0ABR3Z9Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004287</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06408">
        <property type="entry name" value="PB1_NoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051864">
        <property type="entry name" value="NCF2_NOXA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034892">
        <property type="entry name" value="PB1_NoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175">
        <property type="entry name" value="NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175:SF0">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN C23A1.17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="5">
        <location>
            <begin position="432"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="249"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="521" mass="58916" checksum="B1E06B7BB7DC6D57" modified="2025-10-08" version="1">MSLKQEIETWVAALANYDNNEFDEALKEFEKVSDTSKILFNMGVIHATLGEHEKAVECYQRAVRLDQYLAVSYFQQGVSNFLLGDFEEALANFNDTLLYLRGNTMIDYAQLGLLFKLYSCEVLFNRGLCYIYLQQKDAGMQDLSYAVKEKVVEDHNVIDEAIREEAEGYTVFSIPVGVVYRPNEAKVRNLKTKDYLGKARLVAASDRANAFTGFAGSEIKNAGKLDVKDDRPADNISFAATNLVKADIQSRRLQSEPPVGRNVFPPTPPPENDKQGGISRGASVRNGPKPMPAKLNIDRARPNDRYEKTSSPQDGRPRLQRSNSAAPSRAFSQRGPPPSRRQQVEEEDAYPDELYDMYQGGGGNDRGSRSQNSQQGRRQQQRYIEEEDEGGSDYDDGSFDEGDFEMVSNRRPGTNSMSGSSRGQSRRPEIRKIRVKVHAEDVRYIMIGAAIEFPDLVDRIREKFGIRRRFKIKVRDDDGPEGDMVTMGDQDDLDMIVMTAKSTARKQRLDIGKMEIWIQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAI6</accession>
    <name>A0ABR3ZAI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetoacetyl-CoA synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003976</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002937">
        <property type="entry name" value="PRK03584.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF1">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="7">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="127"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="75505" checksum="E51BFC6DC5E02891" modified="2025-10-08" version="1">MAATTSAASPAPNELWRHPNPKETPMYHFLEKVNEKHGLKLANYPDLHQWSVDSLADFWAAVWDHVGITASKPYDTVLPTTAMYPRPDFFQGARVNFAENMLFPAGVDIDPSAAALITMTEAWDTLGSEEMTWATLRDRVRRLAAQLRSDAIGLHAGDVVAGFIGNHAGAIVAMLAAASVGAVWTSISPDNGVSAVLDRLVRVKPKVLFSDHASLYNGKLWPSTDKTLQIVDSLSDGGHLKAVIIVDSVKYPGPEPTAADLGLEALRKKVPVAEAYGEFLASAPDEPLRFEPLPPSHPLYILYSSGTTGLPKAIIHTALGTLIQHKKELALHCSMGPKSRMLYYTTTSWMMWHWSVAALSVGASIVLYMGSPFRPHGELSLPKVLSDLRVTHFGTSAAYLIALESKKIKISSDPSIDLSALEAIYSTASPLPPSTFQYVYETFPKLVHLASITGGTDIISLFGAPCPLLPVIAGAVQCAGLGMAVAVADSASPSDDPKLVPAGEEGDLVCIKPFPCEPLTFYDGDEKYKAAYFERFNGWWHHGDFVRLEGADNQSLVMLGRSDGVLKPSGVRFGSAEIYNIVTRFFASEVEDSLCVGRRRAQDTDETVCLFIIPTAGGASFDDLRNRIKTTIRKELSPRHVPGIIEECAGIPRTSNGKKIEVAVKQILSGLQVKTNASVANPETLDWFRAWSNSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBA9</accession>
    <name>A0ABR3ZBA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004077</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="6">
        <location>
            <begin position="106"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="4">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="4">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="341" mass="37474" checksum="F159AB2538E74F55" modified="2025-10-08" version="1">MAAPTATAATGDVPAENTDLSRQYDTPMGLAHTTMQALKDRIKLHYDLASDYYVSLWGEHIHHGYWPTDESKAKESKETAQANLIRLLLSISGLNKEDEGKPLTVLDVGCGVGGTSRYLASNLGARVTGITISTRQVELATKLAEKLAAEGTEGETAPTADDGGFLSVGKGQVRFLELDAEKMGEFFKEDSDKFDVVWISEALSHFPDKALFFRNAHLVLKPGGKLVLADWFKAEDLDETTFNNDIKPIEDGMLLPPMCTQAGYVKLATDAGLRVLAEPKDISQDVKQTWDLSWALVQKPSLWAFALSQGRDGIAFLQAFRAMRRGYANGTFRYAVMSFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCB0</accession>
    <name>A0ABR3ZCB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitination network signaling protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1101"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="752"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="847"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1113"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1150" mass="122203" checksum="8B850309CA960D6F" modified="2025-10-08" version="1">MPRASPSAKRQPGAASQRDSRNDHGTGSHGKRTTRNQQKTSHAPPPTGGDALAQPSSSSGNTAPNTTSSTNPTLATAAAAPSPPPLLAAAAAAASAANGCTRDADSMASSSPAAYHGQQRHRNSDPTLSAAAGSRRFHASDRNQPAPDNAPLATSTDSLAASNVFASTTGTAGASASPSVSFDDSYRRIDVNAAKNANVHRDTGPLDLAMTILRSCPLYDTIAILIILMQLSPVVLSIVYMLFTVLTFVPPVTTSSGLSLTEMFEGGLGTPAFTTIVCMDVVILLVWLFLWGPLQLLILDFAQVVIALTLGGGYNNNASRQGSANNIFVCLGIVVFSHFSHVTSLEKLPHLGPLFAADHSSVFVDHNVSVQQSSRFFSRRMAGASWVRNVFAIHILMQGIVRYIREWYLRREKRDSMANNQADPETGRVTHIQENSTEASVPSATDLDGHAVVSTSTSAAESTGHGLGLSSTTGLSGGSVFASGPASITIDADSISAPTLVGTTSASPATSHVSSKKKKKQSALVRLRQPLWAALASTKIVMIKEYELSQAASESAGAEATDVDNLGNAPFYAQPRQIWVCYVGHDEVCFSTSAFPKEDTHQKLSSTLPQPSSFLIDTTKPFYVRINNATWQPTRIIPVVEGQDGTSSDQADGRERDDHHSAATRWTGDIYGLTPLSSYECEFVSTRSGEVLFSTSVRTAAAPSKSAAVAAAKPVPPSQLRPHESPATTIKASITTQEVKLNDEKARVKTLRKDNNRRVNSLKKEIDRLAASVQSSGGNDEKFKQKITQNTVQQKQAEQAIESIEAELKDISTVPEEVLSQYRNKKSEWDREKAQFDGVIASFKSFKSAVDNEIRSLEDENATFQAKRNKIASRIAKADSEHAQIMDANARGLDEAERRRQERVNIENEITRSNQSYIERLLAVQNANEEKVHTIEALHETMRSFYSSFDSERPYENRYAVGSAPVVQGTNGVPTSAPGAWPTPHMPSSTLYIPHASWAPVPTLTTSGISPIASHAAPATTFMHIQQLQANPMPPLLRMRGRSSSMLSDVSGFTQSSTADDDNMAAQIGSNVNSASQTSGVFVSSSVLSGQTSQAGTIRAPPVFGITHDQPGCGSGSGSGSGSGSGSGSGSSVHSGSGSVGSARDPSSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCX4</accession>
    <name>A0ABR3ZCX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyketide cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="19932" checksum="F8D1E89EE8513173" modified="2025-10-08" version="1">MATPTAYAILWPTKFLPGTTDNYVSNEVIAAGLTANQVWPFLADTAHWEKYYDNIGQITPPASGSLLTPEAVGSRFRFATFGFPPLDIELAECVPPTATTPGRLAWRAWQDGDADSALEVYHAWVVENTPWSSEGKPFARILTQESQIGKPAAQLAEAQPNPMLNGHQSWLDGLVKYAKSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD52</accession>
    <name>A0ABR3ZD52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C6 zinc cluster transcription factor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TFC7_1</name>
        <name evidence="2" type="ORF">Sste5346_003858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1898001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF51">
        <property type="entry name" value="TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="269" mass="29200" checksum="84CDBD4A7AE56EC7" modified="2025-10-08" version="1">MEQFRSNWRGDPMLGDDAPPQPRLPTGNAADPALSDYGIIQSRELAAHLTKNTGSAMPVERMYCSPYYRCLETVQPLVNTMTEADGGKTKEVVRCEPGLVDWFGPLPFKHPQPLPAAELRDRFFPWIDAAYIPSVGGPSPEGESMAQLHARLAAVVGSIVRQCDAEGVRSVLLCTHAAPIIALGRVLTGQVPADVGAEDFGVFTCGLTTYRRRQQPPVAIDPSTIFSWDDPQKILSTQTWTHGRGVGGGWDCAVSCDCSFLSGGEERGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDQ8</accession>
    <name>A0ABR3ZDQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="52896" checksum="EC3F7ABA359CA50F" modified="2025-10-08" version="1">MADEASRSASSTCRLVGEPMPDIAGIGILVGFSGQAFLSLCLALWVFFFSRHGRLDLRHEDGSDEHAIETKRLEMVQDILMIGNDIQVMMGMALMITVFSSYNHMDVYHFRLIYDIVSFVGVSIAAALVCFSFCTARKDKYKQRRIRRATGLPDENETAGQHKRQSLPQTVRGWIDSVRKVMPALHKLNKKNPIVKKFAMSARYRITYLFAASFLTLTILLNTKLGQWNDDKEPGACYNTAYTSTPGAHHPQADRVYVWVTCGWMLSVMMFAVFDGSSHRRYILLAAFAQFPLHFYMMVALRTANQGLLGIPTEDNDAASGDGGGDNSENDWDFGQTTAVLLFTVTVVEAISKGREFFQFERSVKKKRAAIDRRQLARENRDGDDGEDERDLVNFNAITNTTTESTTIKNGESSWLHPWKLQTPSQRHPSNASGGDSIAMINTGASSSAAAVNNSVSRGSGPYDVEAAEPTNPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE38</accession>
    <name>A0ABR3ZE38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="242" mass="27834" checksum="DFC43AC0A3A657D7" modified="2025-10-08" version="1" fragment="single">MWDLVGEDVGAMREQELMSTTEFWGYMASRGSKVYRHRNTHSSAMKLIGHFVQTESKMTLEIQEEMVHQHKDLDGTAAAATVNAQLEQERARFTAELQNLKAELEEAVRKKDHDTIDMLQEVREEYKSELAQIKTAHESLRASMQELHEERYANLERAMKEQQETYKTELSAAAQSLAETHTPTNYIQVTADDFTKKPQAYGSQELNESTAENFSGREEHDSIIWDTMTGRRVSSLYSHNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL0</accession>
    <name>A0ABR3ZEL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF9">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32804" checksum="E6A2BB1E1D0190C7" modified="2025-10-08" version="1">MSNSSDHRVSANGVGALPFTPLMVPALIFAIVYAVMLFVQLLVVGRFWRYYGNAIGMLCGSLLELLGYIAKVMLSHDRFNKNGYIMYIIGLTLGPTFISSALYLSISALMREHPTARFCFLSPKAFTTLFILGDFLCLCFIGVGGSLAAIYADQPIGVDLMIAGLGTQILFTSIFCVVLACLYRRLSHTNGGLDKRTAQYGALLGAASACLFIRSCWRAAELSDGFNGPLASKEGVFIALDSIPILIMSVILIVAHPGFWFKSTRSSHSPSLSISAFARHEHQMMLHSRDSPEMLVKMGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFS1</accession>
    <name>A0ABR3ZFS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein argonaute</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ago1</name>
        <name evidence="5" type="ORF">Sste5346_003136</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="358"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="646"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1013" mass="114637" checksum="340BBF2883154CE0" modified="2025-10-08" version="1">MSGQSQQGGPPPGHQRRPSHGSQSGGPPPGAGHQRSSSQSSHQGRPGNLELSQQTPSGSPGPSSPRGPNPFVQGMGFDPARDKMEESRRREKEVPNRMDLPPEAFVTDGKKPLFAARPGYNEKDRPVNIRVNQYRVEQTNAVTVYQYAVSLVPEPPKSIVYKKCWASHAVQKHLERDPQVWLYDGRSLAWSICNKQAPFKIAIDLDAEQGKQGRPGHPNQFIMVIRQTSAIYLDSLMSYLRGKSGWDTHILECMNFFDHALRQKPSQSMTAIRRNFYHPKAPKRDLDGTIYASKGIYAAFRLSESIRTGGSGLGINVDVANTTFWKDQTLDRLVLNLINISSDKWNVRTPVELANLLKPIQWVGNEKTREPTMSDAFKVLRRLHKLRFKVFHRGKKNDTKTYTIGRFAWHQKYMFEGATSKNYTFTLRKTGETRTVYDHYLKQYDVPLQFPNFPVIETTRDGAFPIEVCHILPWQRYNFKLNGPQTSDMIKFAVTRPAERAKSITENVNRLGWNTDEYLREFGIRVNTEMTKVQARLLKAPTVQYKNGSANPGTSGRWDLRSKLFLINNKGRELRSWGLGIVDGCIDFPTAQNFARVFMKTFKDHGGLVEKPPHLTTFPRGKDLGDAFADAYNATRDANGGEDPVIMFWVLPSKNSFPYYRLKKNGECRFGIVSQMLNAAHVRKAQPQYCSNVSMKVNAKLGGTTCRVPAEGASPSSPAFFTQPTMIIGLDVSHGSTNMKGELEPSMAAMAISWDKDAAKYSAFCQTNGYRQEIVNSVRMTSIFENALHKWCQTLNCKMPAHVFYFRDGVSEGQFQQVMDFEVAHMKAIFQKRCGRVPKITVIVATKRHHVRFFPEQGAGDRNGNPLPGTLVEKEVTHPFHYDFYLCSHTAIQGTARPVHYHVIHDEVKMPTALLQKMIYQQCYQYARSTTPVSLHPAVYYAHLAGDRARAHENVESDRKDPDMVRKALESWNAKKTSGSVTHPTESLPLLPMGAKESVDKNRNFTPYTMWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGE2</accession>
    <name>A0ABR3ZGE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22448">
        <property type="entry name" value="KH-I_ScSCP160_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22449">
        <property type="entry name" value="KH-I_ScSCP160_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22408">
        <property type="entry name" value="KH-I_Vigilin_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054548">
        <property type="entry name" value="SCP160-like_KH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22952">
        <property type="entry name" value="KH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="232"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="406"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="726"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="793"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="888"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="963"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1044"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1113"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1226"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="840"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1303" mass="141635" checksum="5F37D85EEC8F9006" modified="2025-10-08" version="1">MASGSSSTADSGNASSAAQRLLQEHGSHHVTIETVPDEEDLKHDAVVRREAAEAAASGPAPAEAPAASWAATPSAKAAGKQKAPEPAPAAKLNTHSHELFPELGAPKKASANVAPIWNAKTGGAANGSNAASQPTSNGGSAQAASASARSTAPPTLNIPGRNVSSVTLEDHQLLPRGSLKRPIPDIIKDINRKSRANITMLPPTGSRRQFNATGPPDVAQQALRDLVQQIGAKVTVNVPIPQSVRPHIIGKQGSTIKSLQEKTGARIQLPKADEVQAAYEDDDDATIDVTVEGNALSARAAQDAILKIVGERSANTNTRLRGIPSEFYPFIADPNFGLLSNLENNGVQVRVPPLQPRSAQPPTVAAGGRPVFTPSVDNHISLAGERNAVLNARAEIEKAAAALQQRLQLQQTSIPPGRQQFIIGQHGTPMEEFFNETGCVVILPEDAEDDSVTIIGEADRVEAGLERAIDLAMGMQCSNYDISRFHRQAPGSAAAHARNVTRYLRQRKEIERLEREYQSHINTPFTSEGALPWELYSRDGKNAFRAQNEIKNIISSHPPSRMASIPVDPFFHQFLRNDVRPRVQQDYGVYLVVPEASEPSAPVLLVYEGPSDEASAPYTLPQTVPSPQDVAAFQQGVRDAQKHILELIGAQEDIQTTPIEVPLKFHERLRRFIKKEQEARPSNQPPVRVSSLGTVVTLRGPKTSVDELLVKINAFVEQEKEDEKERGFTLSFDFPKAYANHLIGKGGSNIRELRDKFDVEIQVQDGQVELKGPKAKAEDARAHINSVARHLADETTHILKIEPKFHRELIGAQGSTINRLQTRYKVLIFFPRVAKAARDDESVTDAASDAGKPRRQQGPDEVIVRGPKKGADEAREEIMKLYLYLKETSFTATIEVQQKQVPYLIGQGGSAMEALRQQTGAKIDVPNSRGDPDSTVEIQLKGTKEQVTAAKKILLEKKAVLDDTVSTTIEVDKKFHKALIGPGGSTIKDLVVKAGGSDDRRELSRAIQFPNQDSNDSAIKIEGRRSFVEAIAKSIQEFVDQRASQVSETIDVPQDKHRSLIGRGGETRRQIESKFSVVVDIPRQGEERTDVKVTGAPENVQKAKEHIQSLIKEQHATTIQVPRSLHHTISNNGQFFRRLRNENQVTVDHAGQSVPARPVAAAANGNSTLPLITDDEDAADGAHSWRVVEVSSTETGEIPWVLHGTPENVEKAKKALEKAIEQSGQSNATGYLVLPDSKLFRHVVGQGGKKIDSIRKQSGCRIFVPQGKSGQDAIEVIGTTDGVETARELILAAVKEGTQKREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGU5</accession>
    <name>A0ABR3ZGU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF26">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09470)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="75"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="59576" checksum="2E6261DC3ADD50E7" modified="2025-10-08" version="1">MTTEELPSKVAVAEVENSRVDSCMADTEKDMSKLAAATAGHGDVALALFADVDDIGEEIDPEEEKRLVRKIDKLLLPLCAISYIFFFIDKTTLSYAAVFGIQADLNMHGTDYSWLSSLFYFGFLVWALPSNLLLQRLPVAKYLGVNIMLWGILLMSQAACNNFASLAALRVLGGAVEAVADPAFILITSMWYTRREQPVKIGLWYTAVGLGVALGGLLGYGIGQIRGHLASWRYEFLIIGALCTLWGVVIILVLPDNPVAKPPPAGRWLFRLTDRERKLAVERLRDNQTGIENKTFKPRQMLEAVLDYKTYFLFMIAFCQAIVNGGTTNFGTLIIKGFGFDTLTTTLMNIPYGAFIFLVILLGVWINDRLPPNNRCFVLAVFILPTLAGAFGLHFVPDDRRVGRLICYYLTGSLNASFVLLLSMQTANIAGHTKKVVTSACMFLGYCAGNIAGPFFYKTDQAPTYPLGIWSMIVVLILEIGIVIALRFLLSMENKRRDRLQGIDQTHHQERRDLDATAFEDMTDKENLNFRYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH61</accession>
    <name>A0ABR3ZH61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial resolvase Ydc2 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16963">
        <property type="entry name" value="CCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039197">
        <property type="entry name" value="Mrs1/Cce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015242">
        <property type="entry name" value="Ydc2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072:SF1">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09159">
        <property type="entry name" value="Ydc2-catalyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial resolvase Ydc2 catalytic" evidence="2">
        <location>
            <begin position="93"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="381" mass="41592" checksum="C5AED05961D6F266" modified="2025-10-08" version="1">MAPQYARRGLATTKAKAKRAPRKTVKKAAEKKLDAPAEDPRLPVLSLTALRDLAVLCGRNSSGTRAVLRADLEEAMDETPPTMTEAKKSPQRILSIDMGVRNLAYCLLEMPSSPKGGHSVPKLVAWERLSLIGGPEKDESEESAAKLPASTFSPPSMATVAARLIRDRLLPLSPTHILIERQRFRSGGAAAVLEWTVRVNSLEAMLHGIFAYRQLEETASNTVQTVQAVSPQRASRFLLQGGMGAGHAKELLPPRTGKTKEKNIKDAKEAFVAGLLRTPKSSKLVYDESTRGMVDAFLIRWEAKQSRGRVKSKDETTKTKSDTKPKSEVKPTVEALITLSKIDDLADCVAQGLIWIEWEGNKAILRAKGAEDLLATKQLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHP9</accession>
    <name>A0ABR3ZHP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002796</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="312"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="651" mass="70289" checksum="D1B1CC6CCABCC9DA" modified="2025-10-08" version="1">MRHQPNQQQDSQNGQRHDGQHGQGQQLQQQLPQQQAQQTQASQQREQPTEGLSFLSAAAAEMDRRPGEAPPFALAVPESIPLTIPPLPPTADAPAASSRVSPEPLQTDLQGHYVGPASGVSFLLRVQKRLHDNVSFLQQTSSSIFTFGDAPLQPTAQAHDDFDAAGGSDMLFLTQPEANGLLARYFDFAVPTHRFLHRPTVESWLNTFYATRGRMSTNSSGSGNGNVNGAGNGRETREDGRAQAAVLFMVFAQARDYLPASAVGPDMDSSAHYYRAAELQLAREKGAVRLASVQARLCQCFYLLSQSRINHCWSLFGTTAHLALAIGLNRNRRADPAGGLSHIDVECRRRTFWCAYSLDNYLSAALGRPRTFHDEDIDQELPSIAEDGDILHGEIIRRSTPTVGLSLGGQSMGQGVGQGFVLGLNMNMGMGGGGGGGGTLRGMSVMLAPVAHVRLSKIVSMILRDLYAIRPISSTARASLTAKHTAALKAWREEDSGLSRFLDADRVSASLLIPIFQRQRNVLNLAYWHALLLTHRPVLLSNFAYLRQGVSGSSSGGGNGGGNGTTSGNNGSSRADARDPDVRAQAQASMQQCLDAAMHIIEIVDDLFQDGQLFRAYWVGLLLMASSYLSANAFSSQCTLPSRQSLSCTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHX7</accession>
    <name>A0ABR3ZHX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="13">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">DRS2_1</name>
        <name evidence="17" type="ORF">Sste5346_002683</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="595"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1147"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1189"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1227"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1255"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1294"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="278"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="16">
        <location>
            <begin position="1076"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1899817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1404" mass="155617" checksum="16E1A1D8668FA7A3" modified="2025-10-08" version="1">MTGRPPQPPSGGYASARGNNNDLLLDLDDQPIYGGGQRSDLNDDDLMRTYTLDHDETLPTRPSVSYDDFVGAGETTHPSVKTSPGGTNAFTPGGGASSRGVGGNGSGAGAYDSSYASSSSARPGGPYFTEADRQYSQTSGLGNYQRYADDFEDYPEDGQSYYHQGGRINSGDTPGHANARNRNSVLGLGGGLLGRAKNMLGMGQAGYSEMDLPLTEAAAGQRMGGGGGGSGGGGGGGGGLAPPDDSGRRQKKSFDMGNFKFGFGRNKVDPATLGPRIIHLNNPPANAVNKYVDNHVSTAKYNIITFLPKFLFEQFSKYANIFFLFTAALQQIPNLSPTNQYTTIGPLAVVLLVSAGKELVEDYRRKQADRSLNLSKARILRGSSFVETKWIDVAIGDIIRVESEEPFPADLVLLASSEPEGLCYIETANLDGETNLKIKQGLPETATYVSSSDLSRLGGRIRSEQPNSSLYTYEATLTIQAGGGEKELPLNPEQLLLRGATLRNTPWIHGVVVFTGHETKLMRNATAAPIKRTKVERQLNMLVLVLIGCLLALSIICTVGDLVMRNTSGQSLDYLYLAKTNTAGSAISTFFKDMVTYWVLFSALVPISLFVTIELVKYWHAILINDDLDMYYDKTDTPANCRTSSLVEELGMVEYVFSDKTGTLTCNMMEFKQCSIAGIMYAEDVPEDRRATVQDGVEVGVHDFKQLRQNIKTHESAYHIDQFLSLLATCHTVIPEQKGNEIKYQAASPDEGALVDGAVTLGYRFTARKPRTVIIEANGVEQQYELLAVCEFNSTRKRMSSIYRCPDGKIRCYCKGADTVILERLNDDNPHVEATLRHLEEYASEGLRTLCLAVREVPEHEFQEWMGVFEAAGTTVGGNRAEELDKAAELIEHDFYLLGATAIEDKLQDGVPETIHTLQQAGIKVWVLTGDRQETAINIGMSCKLLSEDMMLLIVNEETAAATRDNLQKKLDAIRTQGEGLAIEMDNLALVIDGKSLTFALEKDLEKLFLDLAIICKAVICCRVSPLQKALVVKLVKRYQKQSILLAIGDGANDVSMIQAAHIGVGISGMEGLQAARSADVSIGQFRYLRKLLLVHGAWSYHRVSKAILYSFYKNMTLYLTQFWYTFQNVFSGQVIYESWTLSFYNVFYTVLPPLAMGILDQFISARLLDRYPQLYGLGQRNEFFKIKIFVGWILTAAYHSILLYVFGELFWYDDRMLSNGQTGGHWVWGTALYGAVLLTVLGKAALITNNWTKYHVIAIPGSMAIWIAFIAVYGTVAPLIHISTEYEGIVPRLYSSAVFWLQMVVLAVLCLLRDFAWKYFKRMYRPETYHHIQEIQKYNIQDYRPRMEQFQKAIRKVRQVQRMRKQRGYAFSQADESQTRVLQAYDTTQVRGRYGEMASSRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ6</accession>
    <name>A0ABR3ZJJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002287</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF70">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="59"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="515" mass="57111" checksum="50CDB5D0D6B12046" modified="2025-10-08" version="1">MADEKTPTVAIDGSDKSTPITTLPSKDLDETYDVYAQENPAAIDPCEARHVLRSIDWHILPLLMGSYMLQYLDKSSINFASVYGLQTGTHLHGQQYAWLASIFYFGYLVAQYPAGYLLQRYPAGRFLGGSMIGWSILLLTTPACHNFAGIATNRFLLGVTEAVINPGFVLIMSMWYTRDEQPLRLVAYYCMNGVAGIFGGLLGYAIGHITTGLAQWQYVFLIFGAVSFVWAIVFLVFMPDLPTTTRFLSRRETVVAVERVATNHQGVKNHHFKTYQLWQTLRDPKTWILFFMSIAAQIPNSALSSFTSIILQTFGFTALQTQYMQIPGSVIQIVSLLASGYICSRWPNMRCLVMFVGNIICVIAAGVLVGLDPGPDGKGNKWGRLVAVWLLSFISVGFSLSLTMVSSNVAGYTKKQLTGAFVFVGYCVGNIIGPQTFRASEAPLYHSAYVAILIGFSFKTIGGLVLYGYMWAVNKKRDRAAAADPRTPEERAQNAVEKGMRDITELDNEDFRYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK23</accession>
    <name>A0ABR3ZK23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TIM50_1</name>
        <name evidence="4" type="ORF">Sste5346_002150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="249"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="558" mass="61381" checksum="7439D796B7ACAD6B" modified="2025-10-08" version="1">MLLRAAAQRLRSPAMAPAVQRSTAAIARVAVANSTSATSATRPALFSTTALLAQNGRFTPPSDKKPAQSSSSSSPQKPSPQEDKSQQPAESSDATPEETPKIDLSQLPDLTQGIPSTLEHETASSSNKAAALAALEGEATASEGGAGGPGGPGGREKGELPASAYVSSSEKRRQKVANYMFAGAFGLGVLGTIYAGRDWDEEDAKRHPDIPNGWGFGLWWNRVSTRTKELLSYYHEPAFEKLLPEPDPVYGRPYTLCISLEDMLIHSEWTREHGWRIAKRPGADYFLHYLSQYYELVLFTTLPFAIGEPMVRKLDPYRFIVYPLFREATKYKDGEIVKDLSYLNRDLSKVIIIDSNAGHVRAQPENAIVLPPWKGNAKDTDLVALIPFLEYVYTMQYGDVRKVLKSFEGKDIPTEFARREAIARAEFEKQLAAQRRGRPKQGSGGGIGGLGSLLGLKSSNMSVMVPADGELGIAEQLAQGKMLQDIARERGQKTYEMMEKEIRENGEKWLKEEAAMQEKMQQEAMQNMKQSFTGWFVSPEQQAQQAAQQAAKAAEASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK52</accession>
    <name>A0ABR3ZK52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">SWR1</name>
        <name evidence="20" type="ORF">Sste5346_002280</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SWR1 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSA" evidence="19">
        <location>
            <begin position="415"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="991"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="1550"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="534"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1809"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1894"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="209"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="665"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="793"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="818"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="831"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="877"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1809"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1898"/>
            <end position="1913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1900557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1913" mass="211259" checksum="841E9EA756D6AABA" modified="2025-10-08" version="1">MKETASPGPTATLPDRPPIRFDDSDDSPLDDLSSVPSDDELSLSGAPETPAPAKRASTPPSSKGKNTKTNGQQNGSANGTSTSPLTNGHGNDNGPAKDSEDAKDTPDTNGDERPAKRQRTRASTPPPPASNGKEGGGGRKPKPISPPWKTVGAEGVTTFNEGGRRKSGRINTVPLELRTGDKRITRRAVQSHQTSPPSSSTANGHATRHTAGSSSSQHAASPSSSGAAASRRLSTTTRAAASSSSRSQPSQHTPSSSSTSRQQSSRRAVEPRTSSRAARRSSPSPTTRSTPSSAAGTRTQPSRSSRNARPSRDAAALEMPTRTTPRIRLRTRTLTIPIVHPDQTKIRPRLAPTLPEYFTVAETIPVEEGGQFASEDDPRMTDEMAASEAVIIARIERETEEGGILTAPRCIAFEPEANEEPPRQWAHNDHMVKAVANFRKLMGMEQQRHRAAAKRLAEACRDEWIRRQPKSAEQIEAEARAMWIGRYRIVMKAMFGTWENVRLEINRRRVREWEAEEQRRVKAALQEAVAMSEQKLQARRTQQDSEALSGDDEDEDMLDDDDDLNDDELESFSELHDADGSSLDGDEDDESNMSSSDDDEGEEEDKTGDATKGKEDATTSDEGLTQEQLRQKYANLPALDLSDKATADDGDDSKAAADTPNPTNDNEDDTSDESVDMDDDLGSSEMDSDDDDDDDDSDAADGSDGEDETGSEDDEQAGGLLGMLFGKSELKKLKTEPTAIKEEDVDEPQMPEASSEGKGVPATTAEEISAPLTNGHTNGEEDSKTPAAPSTDNVDEFNDDDDVAMVDMPESDYEEAATDTKKAEADKTDAVDPAPAAEPEVQQDKKDDEPTVVPSLDACVAPPTDEDKTVASPETDAVTTAVSVERSQSPRTLDTKPSDLDTPMSTDADAIVDATAEAETTKSTKDDDEADVIDIDRTDDNAPGATTKEVSVSRSVSLAPTTTGATPKTEIPFLLRGNLREYQHYGLDWLAGLYANRTNGILADEMGLGKTIQTIALLAHLACHHEVWGPHLVIVPTSVILNWEMEFKKWCPAFKILTYYGSQEERKRKRIGWNNNDIWNVCITSYQIVVQDQQVFKRRRWHYMILDEAHNIKNFKSQRWQSLLGFNTQARLLLTGTPLQNNLTELWSLLFFLMPPENGMGGFADLSEFHDWFHKPESQILESGREEMDEEARAIISKLHKVLRPYLLRRLKADVEKQMPAKYEHVELCRLSKRQRELYDGFLARSDTRATLSSGNYLSIINCLMQLRKVCNHPDLFVDRPIMTSFRMPRSIPALYETATEQIVRRAFVPPRDTAQTLLEKVSLNFLNLVPTLHETSLSAGVASRINQLASNRILSDLKEAQRTRLPQPYPDLDASTVQSNLAYLENAVRWRRYEELQHGAYVNALRRQQRPVYGQSLLDMLTLDVQSRPFKPRPRVPAQIMAWFESDSFLLHNAVQPLERRSSAMEMLITKFACVTPAVVTCDMNSVILGQRGVAAFTEEDLVLSAPIKRLPFMERQPPRDPWHEARMRLTIQFPDKRLLQYDCGKLQALDRLLRRLQAGGHRALIFTQMTKVLDILEQFLNIHGHKYLRLDGATRIEQRQILTDRFNHDNRILCFILSTRSGGLGINLTGADTVIFYDQDWNPAMDKQCQDRCHRIGQTRDVHIYRLISEHTIEANILRKASQKQMLDDVVIQEGEFTTDYFNKMSVKDMAGDVVDHALEDGATLEVQNDTTDGIIGRFHESNVAANAAMDRVLGGVNNDAGPGAGALDPRTAGRVLEQAEDTEDVAAARLAEKEILQDDADFSEKPAGAAAAAATATTSAGTPVPTSGVSSTRQGTPLDPTRSGLGLFDPISATEVQAAPVEHNAWGGVMHTVDDYMLGWMGIMLEGTALELPKDRKKSKKRRGKDTRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKT9</accession>
    <name>A0ABR3ZKT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF34">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE SED4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046306851" description="Peptidase S53 domain-containing protein" evidence="9">
        <location>
            <begin position="29"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="10">
        <location>
            <begin position="238"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="577"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="615"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="635" mass="66427" checksum="EF6E0FB239791182" modified="2025-10-08" version="1">MAYSTLRSGMATLAAIATTVMLLPGTNAAVVSKIDAVPAGWTAVGSSTAKTFKTENTNTGTDSSDTHVFTIALNMQNIDQLESRLLAVSTPGNADYGKFSDVDDITSTFGPSDAAVSAVTSWLESSGVVKGYAVRGAFVDLATDVAGANTLFGANYQYYTPPSTAVSTSTKLRTLSYSVPDEIAEHVALVDPGNYFGAVRSFAPRLGDLQFAERAPPTAAKAPSKATTTTIDAACQTSITPACLKQLYQVGDYEADAKSGSRIGFGSFLNQSALYADLADYLTLNGLPSQNFTVELINNATNDQNPATAQIGEADLDAQNIVGVAHPLPVVEFITGGAPPFVPNIDQPTAADNQNEPYLPYYRYLHEQSNSELPQVISNSYGDEEDSVPYNYAVLTCNLIGLLGLRGITVIESSGDLGVGAGCLAPDNKTPEFNAIFPATCPYLTSVGGTVDVTPEIAWEGSSGGFSKYFPRPAYQALAVGAYLAEHVSASTYKYYSAYTNWNGRGFPDVSAHSVSPDYQIVYAGKPGPSGGTSAAAPVWAALVGLLNDARLRQGLPTLGWLNPLIYTFGPEVLTDITAGQAIGCDGQNTQSGGAEPAGSGIIPGAFWNATTGWDPVTGYGTPNFGKLLSLVTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL08</accession>
    <name>A0ABR3ZL08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">sphinganine-1-phosphate aldolase</fullName>
            <ecNumber evidence="5">4.1.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sphingosine-1-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DPL1</name>
        <name evidence="8" type="ORF">Sste5346_001806</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008117">
        <property type="term" value="F:sphinganine-1-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050477">
        <property type="entry name" value="GrpII_AminoAcid_Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735:SF6">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="62708" checksum="3587C8944BD6E50D" modified="2025-10-08" version="1">MPGSSSMLISLRENISNVRRRPATPLLLLNLDLLRNLVFFFFVLRLTRRTVWKLRGRGVAGSISELYHDIRRIIFGWFLRLPGVRTKVRQQVDEALGKMEGKLVPVGVTRHTALPAQGLTHDEVRKQLESLAELDHTRWEDGRVSGAVYHGEDELMKLQTEAYGKFTVANPIHPDVFPGVRKMEAEVVAMVLGLFNGPAGSAGVTTSGGTESILMACLSARQKAYAERGITEPEMIIPETAHTAFHKASQYYKIKLHLVACPAPGYQVDVRRVARLINPNTILLVGSAPNFPHGIIDDIAGLGRLAVRKRLPLHVDCCLGSFMVPFLEKAGFETTPFDFRVRGVTSISVDTHKYGFAPKGNSVVLYRTAALRAYQYFVSADWAGGVYASPGAAGSRPGALIAGCWASMMAVGESGYLDACGRIVGTARKFAEHITSSPVLAPEIEVMGRPLVSVVAFRARRSAPSTSSSPFTPINIYALSDAMSARGWHLNALQNPPAIHVAFTMPVAKAFDTLVSDLEACVEAEREKARVRAVEGGNKSTPEDSGDAVALYGVAGSLPNKSVVVDLATGFLDLLYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV0</accession>
    <name>A0ABR3ZLV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydropyrimidinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050378">
        <property type="entry name" value="Metallo-dep_Hydrolases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647:SF96">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647">
        <property type="entry name" value="HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="25016" checksum="D3B1926F37B54DAE" modified="2025-10-08" version="1">MLFAAKHVCSPPPRDKTAKAIWTGLRNGTFTVLSSDHCTFNVDDDVTGKKTCISEEFPVGRFRHIFKGLPGVEMRLPMAFAATVRLDRLPLTKLVEVTSTNAAKLYGLYPKNRAMMPGLLDADLVIRYPNEGSPKRPAALDNLTISNSMLHHDIDYTPFEGRRVTNWPRYTVLRGKVVWDRDREGIIGCKGYGRFVEREASTLNDIWQRVKEAGPFDEEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMI9</accession>
    <name>A0ABR3ZMI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL10A</name>
        <name evidence="5" type="ORF">Sste5346_001769</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_uL1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="217" mass="24006" checksum="28442C4D9C2F7722" modified="2025-10-08" version="1">MSKITVAGVRANVVEVLEYSNETKKRNFLETVELQIGLKNYDPQRDKRFSGTVRLPSVPRPNMAICILGDQHDIDRAKHGGVDAMSADDLKKLNKNKKLVKKLARKYDAFIASETLIKTIPRILGPGLSKAGKFPTPVSHSDSLSDKITEVKSTIKFQLKKVLCMGVAVGNVGMDQEQLVANIMLAINYLVSLLKKGWQNVGSLTIKASMSPPRRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMP8</accession>
    <name>A0ABR3ZMP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Complex III assembly protein translocase and chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">BCS1</name>
        <name evidence="15" type="ORF">Sste5346_001641</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="52"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="276"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="512" mass="55470" checksum="C30DAF88B19F3201" modified="2025-10-08" version="1">MATPDTIQPPTAVPAAPAGVSLPETSTPPSSSIFNLDTLFDNPVFAGGIGLAGLGAAAAAGRRGLIAGAQLLRRRLLVNVEISRRDPSYPWVLAWLSEPRAPGGFLAQRITRIHNLSVATSTKSMNPGGPTPATGHGGETHDGPVQASFFLQPGYGRHIIQHRPGVFIAVSREKQSTANMATGEPHETVTLTTLYAHRHVFEEVFSQAHALAAQAAEGKTPVYSVQGMGWGTLGEPRTKRPLASVVLDRDVKEHIVADVRDFMQRQHWYVDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDFGLAVVNLSEIGMTDDKLAMLLMKLPKRSILLLEDADAAFVNRRAVRDSDGYSGPTVTFSGLLNALDGVAAGEERIAFLTTNHIDRLDPALIRPGRVDMMVRIGEATEYQAAQMWDRFYGDIDKDGAGRERFLQRLRDLRLVEDESGDAAVAQKTDDSVPRRHTSTAAIQGLFLFNKNDMEGAINMAEGLIPRQFEPEPSDPQGAIKTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMX5</accession>
    <name>A0ABR3ZMX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphorelay intermediate protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">YPD1</name>
        <name evidence="3" type="ORF">Sste5346_001906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045871">
        <property type="entry name" value="AHP1-5/YPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242:SF52">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="Histidine-containing phosphotransfer domain, HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="26"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="134" mass="14687" checksum="01C22DC310F4215C" modified="2025-10-08" version="1">MSFDFGDSVSESAFEQILEMDDSPSNRDFSKTLVYDYFDQAKETFQGMDAAVADADLAKLSDLGHFLKGSSAALGFDKVKDHCQVIQQYGKKMTLDGTPETDESVCLARITEALTAAKANMTIVEGKMNEFFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNQ2</accession>
    <name>A0ABR3ZNQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001304</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF8">
        <property type="entry name" value="7ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="150" mass="16054" checksum="86CDDD823EFA2AD0" modified="2025-10-08" version="1">MAGAEQQISFKIEDLFSVKGKVIVITGGGTGLGKAIAEGFATNGARVYISGRRQEVLDTAAKQIGGDVHTIQGDVQTEEGCKAIVAAVQAKEDHIDTLINNAGVNSPWRVQAKDHNNADQVQNLLMNGLTEEDFARSNESKYTPLTKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPE5</accession>
    <name>A0ABR3ZPE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10917">
        <property type="entry name" value="CE4_NodB_like_6s_7s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF6">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224462" description="NodB homology domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="9">
        <location>
            <begin position="691"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="188"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="896" mass="97623" checksum="AFCEBBDD94F3E311" modified="2025-10-08" version="1">MYAKQMLAALLVAGVQADVAATKCSADLQIDNFANFASLTNSLNNPASDDQSMTSIAASGGILQFTPKDPNSYFYETFPCTQAKSQGYGGLQFTLTYPAGTDFTLELQTKTAASGGCSAANYTSEWFAISGLTGTQQVVTLDLGVYEASNLDAISGLVFASFSKVGAYTLSDLKFVCRNLEARAVQEPPALKPNSVQDPATPSVKDVPGLFERNNRKASPADGPSTSDSDSSSSLPQPASSAVSSSAFSIPSFESFAPIVYPLAASSTAAAARDAAKRDAKLHVRADDDVHRSSAHSNIPKTTIGVPTTTRKPIISTTTYRPKPTSAESCKDLLIDDWESQSRLTFLYYNSMYQPSSDDGTMKNIVVSNDNTVSIEPVNTDSYFYSQMPCVDTVDAYGGISLKIKASRGTKFSVQLSSVDICNSGNYTKQQTLSTAELGWTFDGTLQAYSFPLSKFPKIDAAKVSMIYFTSLTEPVTFGPMSFYCGTRASEFPAPAHPVNPQTQYSVPAPAETGSASSTLLIDQFTDPDSNELGQWHGCDEDCVTSVIKDNTVKLSTNDSDLAWYSSLADKCADITAFKDAYLHIPYSGSNKFTISLQQANKDCNPKVAPYPETWDSLEASRYASDTDIYMPISHFNVDLSRVVTFAFKGFYTLDSTTLHKIEIVPSVPEGFKVPNKLPSGNLVFACKRPNSFAFAIDDGDPALAQEVVEIVKSENIHVTFFTVGLPLEDLSTNLSTVYLDMQARGHQIALHSFTHPKMEGLADYAAIDWEYNNDIAAVSKTFNGMHTPYFRPPFGTEGARMRQRLALALNVTDPYVVMWSVDVEDWLWGLSSTPEKQLESFKRDLAKGGNLVVMHYLYPNTVKYLRQFIQLAKATGKQLMRVDQCMMDPRAPPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQE6</accession>
    <name>A0ABR3ZQE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="77"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="38403" checksum="B883001925389E32" modified="2025-10-08" version="1">MASTAMDYEPTNGERFEDDGARYERDDQRSASPRRDEGQESAPRRSASPGAAGDRPKDNGGSRSGDVDDDGAVNPGSNLFVTGIHPRLSEAEVSRMFEKYGEVEKCQIMRDPHSKESRGFGFVKMVTSDQADAAKDGLQGEVIDGRSLSIEKARRARPRTPTPGKYFGPPKRDPRGGGGGGGRYDRGDDRRRGGGGYGGSRDDPYRYRGYERRYDDRGGGYDRGYRDDRGYDRGGYDRGYDRGDRGGDRGGERGGFRDDRGGYERRDREEPYGGSNGGSRGGDRYGPREDRDRGYGGPREERRGGGYDRGGDRDGGRSRDPAPGGPAGYGDAAPRDRDYSQRYEASDPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRP9</accession>
    <name>A0ABR3ZRP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049814" description="AA1-like domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="22677" checksum="7F911A0169D7A88F" modified="2025-10-08" version="1">MQLLAHLPLISLLATAANGLQLLQYDIPDELLALFGPGNPDSVSSSSAAVPIGTGSASSASSASSGSAGSSTPSSSSSSASCFYPATFTLNNFTTWSPATNASRSYVSFNYVDSGTKITTACEYNSSSTSLTAGTELAARYACDDSTISFIWQKGKLTAIETTCPGQTATKFEASGSILPTGLQCSKTNGTDDTGLGQGSGTICLASGPLSANFTSQEPSPVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY3</accession>
    <name>A0ABR3ZRY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000047</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044989231" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="517" mass="56644" checksum="F5BE067C5EC5CE44" modified="2025-10-08" version="1">MVVSIRRLLLALAFVASSTVEASYQTIPSKFSPDNGVRVKKLSDGQLCNGGGDHYTGWLDIGRKHLFYWYHPSRKGETNAPTMIWLQGGPGGSSLAGMLMENGPCLLDAEKNATYYNPHAWNEEFNVVYLDQPVGVGYSYMSPSPGDNGTVDEDEFPSRTEESALDFVVALKLFYEAFPALATKPLYIAGESYAGRYVPMYASSILAYNAQLGEVLPAAGGGNGARIPLVSIAVGNGWTSPYHQVPSLYDEGCYPADDSLEPLFNETECAAMATAVNRCETLLQACIDVPDGLVCRQAGAFCDGHLLAPVNDKLVSRYDRTLHCTAPDKCYPLADYMAEWLNSPEVRAVLEIDAQVGAADPVDGSAFVFESYIIARRYLASGDMYTSTVPALQHVLDSGEVEILYYVGLHDWICNGLGLQRMWDSVHWTRHAAFRATKNVPLSWTLADGRPAGVVRQVDGLAVAQLNGGGHLYPMDQPVSALRMVRQWKTELEEKKGRATVRIGFEAKQQHQLSMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS83</accession>
    <name>A0ABR3ZS83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_001337</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="454"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="260"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="516"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="265"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1902359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="995" mass="107674" checksum="74A08A269A70BE03" modified="2025-10-08" version="1">MVFFYFGPSASSWATGNDYFAASRQLPTVIQTVWDSLAEQSQDKSLGGTRIDWMSTGVDGSYCLMLKDGNILSNRSDFLQSIYTARQTQPYANVDHVSFSPYGAYVVTFDTGEVVLSPETSGRFPDAFVGLASDFVHFAGPKRNTLQPTQLEYVFWGPSDSVLIKARGGALRWQGLPNSLVTELRALTVGVDMLSAGFQLGKRTTLCPWDGNLYFLEFASFLGNTAKAYPYSLRQHGLSGEAMQYVVVNQRPPEHLMSVAAPPATQLPPPPPTPPASAPPGAPLGAPPGAPPGRTPGALSPGAPPGAAPGLPPRPAMVQDQTRSPPTPAPTPYIPGVSPPPRSNATPTPYIPTAETPRVETPVSPLPSFLRPEEQDQHLPSILRPEEEQEEEKKEPPKSEDEERIDAFVNTLAMPADIRSVAEQLWEICTMGVIEEPKYVTAAHALQLFTASNLSSEDIDMIWEKSDLDHNGLLDREEFLQAIYLVAIQQYLRGINDQYGLKARLEAAEFVAAVGGKKEDSASNDSEETSRDMPREAPGAQPSLRGAVKDIFKLFVDTGSQIGSVYTQSIQAAQAQQKALEEQQLAIAQAEYAAQSEAAQQSAQQRLQDALEAMQINSQAAMSASMNAARMNQFGTMNYGSGGGGDDDANKESKSGMAKQLRESLMSSIVTESPNVKWEDVAGLAPAKDELQEAVVFPLRFPHMFQGKRKPRRAILLYGPPGTGKSYLAKAVATEVEYTLFSISATDLTSKWFGESESLVRQLFELAREKKPSVIFIDEIDALCNNRESGGGGGGGSGDDATTARLKTEFLVQLDGVGHGNNDGVVLLAATNLPWSLDPAIRRRFSKRIHIPLPDAEARVELFRVHGGEEWTGVVGEADGPREVAVGTELSRRTDGFSGSDVANAVQDALMLPVKRVRGAKYFKRDATGWWVPCEGNEAGAQPMTWKNVPQGKAKAPPLTVEDFFAAVDRVKPSVGANEITRCAEWTAQFGLEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSA7</accession>
    <name>A0ABR3ZSA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine-rich cell wall structural protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="39915" checksum="9EC2376B0A34E8B2" modified="2025-10-08" version="1">MESINNMASAAAQAVWPNNGNGNATTENANGTSEFNNVNNTTGPSYDNTNNHSNIAANAATSGKYNTSNTDNFNSTSTSNFNNTTTATSATPGSPIPNSNEEPISGVLGDTSKGEPYDAGNKDEQEYANARYSESQSPSGGAGLTGTSGNTGSTGSTGAVGPTGAAGAAGVGGVAGGVAGAKSFDNNTATSSTSVNDVNNANNANNANTTSTTTDNTAAANAGSDNPAATSTTAGEAGMKGSKVPSSGGGATGEPNVDGPGPRPIQEVARENHGDAGQAYSGDRAATSGGAAGGNAAGADDEDDDKPQSTSHGEGTGEKYIRSSGLQADGGDFDAAREGAGREADRILEEKGIAVGGGNQPGANDTAGAEPGNHHGSGNSNGSGASGSSGHKKKVSLGEKIKNKIRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSN2</accession>
    <name>A0ABR3ZSN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras GTPase activating protein ira2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">IRA2</name>
        <name evidence="2" type="ORF">Sste5346_000320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="632" mass="70301" checksum="855DC2F1F54A50E7" modified="2025-10-08" version="1">MRYAPLLSHYTRPAFFFTMNGDAGLVGCLVERLTTRLPHRTGTHGDSLFHDEIVAITRTTLVKVSASSIVIVLDTLLSLLEDLARPYNKIVASHPPHVLLSELYILALLADCCSSHWDASTSSTAPSTASATDTAAGGGVSAKRRRAKSAPLVVLEPALVRRIFEAIKVFMNPTPDGQLLSAKTILDDYTADNLSVPSSASGEAPKTPVSSRSEDVVGAPEMLDSRVSEIEGHVKVIVEYVTASTWKPSLDYLKGVIHKVRTVLSTQVPPPQSLANAEEERSSLVILRLVAYFWVDRQRLGQVLQEVCSSFLHFRKQFQNSIAISTPLLIIRWIERFPHEFVELHVMHLRVDGTPETLFDMAQTVGDNVRRKALLYPLQTTLLFLLPDLFEVASNMREAKGGGVAKKVAYLESLRKMLRNKNEQAAYCLVSLLRVARHFDAESDSALMSYAMDFQDEVREALFRRTPASSEAPLLDQDLLTAAFVSLTHLNFEVCVDSLAINCLVPSAPQSFKIAVIQACSHFARLDNSEQYEPLFNSVSAFVQFQMRVSPSCNPTPPSILTIFCELTGVADNVVPIDKHLRYRLGPTAQIRRLRCPHSDDMQYPRVSQRIANDIVPRRAQRPRRRGPLFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSP2</accession>
    <name>A0ABR3ZSP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MIP18 family-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24679" checksum="81E959586ACB732B" modified="2025-10-08" version="1">MAELQNANPVILNAAQLPRRRLGKDTAAKRGPEFKFDDILAPKTNSTGGAVSSWAAPPVSPPSSLSSVSSGDAYDDVDAFGGDDGDVFTEEPIDEQEIYDLISTISDPEHPHTLGQLSVVNLPDIRITPSPTSAEAKATANDPNALTQVLVFVTPTVNHCSLVTVIGLAIRVRLEQTLPPNYRVDIQVKEGAHAQDDQVTKQLSDKERVAAALENDTLRGVLDKMLETCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTR9</accession>
    <name>A0ABR3ZTR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine rich repeat domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="652" mass="72181" checksum="2DEF069BF103BD31" modified="2025-10-08" version="1">MSPKPRFMRSPSPVGLGRSSFSSIRERDSDLAQTFTSTKISSYSSHNLKQLADEVAVSDEPSTPTSPLSAPSTAGDIVPSDNSMLLLPSQHGAVDFDLQARENDLAQSFARSLAWLNTPIESQVDASSVGLTDTVMEDVEDVKLTQSKQPLERLPFEIYRMIVDHLILDTPPNGIDRRNVDLMSLLVTSSSLYSMTLEALYRRVIVPHSRNFQKFFTQLEAHPDRGQWVRRLDFSHFSPVSLFATASARAAAKNLTSDTLLRCLNMTPNLQEFLVQDYLDGDIDESVIRKLLVGLPRMSALDLCGSSSVQFRNAFAAIAETEGPDSKDSTWPQKLGIQRLSLHKCISLPSTAFEFLLPKLNRLTHLDLAGTRVTNDALMSIPTTARISHLNLAKCSLLTAEGIIYFLTNHPAVNQDTLVFLSLGCDASTFQLLEVEDVTRLLPILPKTLKSLSLKGSKMDQSHMPSLREQAVHLEELALGRGLTLSDVGTLVQNAEASPEEEKAAKEPTPTPHELRYLDISDMEVENFNLTSLLIDGLLLSQKTWPLEVIEVSDPVFKRVSKSNNALHRMGWRQSEIGSRSWLVRGSPRSSVQSSRGRSSLPGSVCIRGTFAMENGQRKWKMGAQSWGMRKIPVAHAKVGGMYGSYMFGRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUE8</accession>
    <name>A0ABR3ZUE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1092" mass="118063" checksum="4F6FE0C4B25E826F" modified="2025-10-08" version="1">MAAKALSPAEAELVNSLTEDDIPTKLRCAICSKLAVNAYKLPCCEQLIDENCHSTLPSTCPVCEHTPLSAADCNPNKVMRSTIRVFIKTELKKRETNRAKQTKDATATTPVAPATPVEAPAAAAATVATDGVAVATIAAGEAQQGQDQSQDQDQVAGSSSSAYSSKPLDNAQSQSQSQSQSQSRAEDSQMQESGHADARQQEDDALADGAALTNADNKTSADTADQTTTENAPSQGDDATTEPTQAVGTEPMTDGDAEQAPSVDGRVASQDGQEAATDEAGNPIANGTANGVNGFNMPGANGAFPGMNGMGGDVNQMQMMMAMQNGMMPGNFGFPMMGMPGLNMDPSMQGMFMNGGFPNMMGGGYGGGQQAWNGGQDNFNHPNASGMGNGDFGSYNGGFNQGYNQQGNFGYQNQTQFNNYRGFGRGRGRGRGFYNNNFNGGRGGYYNNNNGNFHNNGYGPNNTNGMNGNNNNFQFQGQGQGFNQQHGQGPSGFSNGNGNGNGDNEEGHGSANGSADGNANGDDTEMGNNGTSQGPDGPDSVKPSLEDGANGGPVQNGMPNESSDGTAAAIPVFESRNGGGPFFPNSNGQFGMGGPVRGPGPGLSPDVPLNAPSGPKAMRQGLPNTSTLHLRARGFLTDDRPNGATNGSGHNSPATEHSGHGRSRSNSVSTKRRDRDRYRERSRDRSRDRERDRDRDRDRGRDRRNGHRDRHGDRHDSDSGYKREKSAGRDVEPETTEDVDMLAADKRAINNPDLDYERHNDWDEDGIDGPSRDYHDDNGDGGGRERSESRSSYGRKREHSHDSIALEDADQPEGADVQDGTGSRRRRKNRGGKKNRRRRDGDNLHGDDERSGAKSSGDAAGRTRSMSPVDESRRSSGGHRSHRDRDTDKRRDRDHRDRSRDRDRDRDRDRDREHRDRDRDRGRDRDDHRRRSHRDSDRDRDREHRDRDRSRDRGKDKDRRDKDRSDRRDRSGRDRGDKDRDRDRDRDSGRDKGGGTDATNGAAPGGGSSDPYAAERERRTRERVAAEAQKRAGISSLVSGSKRGRDDFDDGNGGGGGGSGSGRRNRRKGRRGEAVVTEDAGRRDNSERDSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUN9</accession>
    <name>A0ABR3ZUN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="462" mass="49848" checksum="1A0128038BC4E5AE" modified="2025-10-08" version="1">MCFIEFVGYTCGHTSMPVLRPCPLTTASHTFPACSRRGDKTFFAGEMCSACQKIVHSRATQIEEYEHRFMHERGVCGCETVFPYLIRPRVIGSCGGGVDEPGVTKCDAQGHEHGGQGGQARQARHGTDIWTVAKKADNNIKPTEIQLPPLLCEATDPGGHTTVSVRLPSLYAAEWVADHRGRHEASLCHCPVDFRTYEEVVGQGSATAAKPEAGVATGESNVGPSRPLRRSASMSAMSSSSDSGEPGVPERQITRSSSHDGLTYFVAVAGEPPNDDKEGTVTAESALDNKQVAPVAQDGGFAVTHAPIQLHPGKSVRYAGSVFAEVPEYLQLMGPFLSQPAMQAQGGDQTVMLDCVLDDNGGNLTLASGGGHEHDRVDYIGRPEHFQNQPGIPTTFIPPSAAHTPRPSRRRPRAHTMADMKEHYEHQAQQRIPLVGFPIGAGPEGVSHAIPWRNRPPCWRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG61</accession>
    <name>A0ABR3YG61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000142">
        <property type="protein sequence ID" value="KAL1887148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="15"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="347" mass="37467" checksum="1EEC95E1AFE765A6" modified="2025-10-08" version="1">MSLPKTMKAGQWDPKQNKVVVNEVPVPTPGENQFLVKIKSASLCHSDLMNMDRAACDYPVTIGHEGVGHIVSFHPSAEGKGFKTGDAVGFGYFVDCCFECEGCMVHNSHCHLGTARIQGFNADGYFAEYAVVDYHNGIVLDEKEWDLRTASAIFCAGITAFNSVDSCEAKPGQWFAVVGCGGLGQLATQYAKAMGLRVIGIDVADANLEETKKQGAEVTFNSRTNPNYIEDIKKLTGGGAHYAAVYTNVQPAFTSAPKVLRIGGTLMVVGIAPKPLEVTAMELVLGVYKIKADSTGIPQRIPKAIEFSAKHNIRPVVDVRGGLDQLEGMVKEMKEGRNTMRTAVVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH06</accession>
    <name>A0ABR3YH06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000114">
        <property type="protein sequence ID" value="KAL1887616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="41"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="288" mass="32055" checksum="90D5B4B2FCF02AED" modified="2025-10-08" version="1">MSEDTTTRGPEGKRQYITHKNGLKTAYIQDNFTDPWTKPETILIQHGFCRNADHFYHWVPALARKYNVIRRDLRGHGYSDYPAPGSNYDYSPSTILEEIKDTLDQLGIEKAHLMGESTSGMLFEAFAATYPDYVLSLTVCSSPTYLSVLGQQFLAFGEISWPEACRKLGSRRWAERLSGAQGTVASNDPDYVRWWIDTVAISDGEGLAGYAEFLCNLDVRPFLSAIKAPMLILAPKNSAMVTVESMEELAASVPTSRLVLIGAAGHEIYCEAAEACQEATLKFLNDFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH73</accession>
    <name>A0ABR3YH73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Quinate repressor protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the 2nd section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000124">
        <property type="protein sequence ID" value="KAL1887375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="5">
        <location>
            <begin position="511"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="4">
        <location>
            <begin position="641"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="SDH C-terminal" evidence="6">
        <location>
            <begin position="817"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="711"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="854" mass="93021" checksum="2A290516D2AF3400" modified="2025-10-08" version="1">MTRTTQPFLAPNALSAPAAALDSNEAWDQDASILLLGIRGSGKTSLAILAASCIDFRVVDADQHFYRETGLPRAVFASQHGFEEYRQRELELMRSLLTDNPVRCIIVCGPGSAEGTGQELLAAFRKHHPVVHIIRDPQEIDQYLRTNDLAKIARLSQLIAPSYRALSNFEFYNLSEPADSTDPTDVDNAAGDAHALSSAPHVSYHPSLVLKHVEYDFLRLIYSVLDQGSCPSVLKARHCLSFLPPESKSFTYVLPIAFDRVLEIAADLRNTDLIVDALELVVSLDRFLGDDGTLDHAAATAVAKTYYTLRRNVRLPIIVHVPAPDAASSAAKPGVWAAYQDVLRYGLRLAPEYLTLDLRCDTQAALALTTQKHSTKIIGHFFDEHPGPDAWDSPARLRLVDCARQYGCNLVRIYQQATSPADNAAVQRFRSRVQELDRRGPDTALPLIAYNTGRMGRASCFVNSVLTPVTHELVAGRQGGAGTADDALLTVQAAQRALYESFTLDPLMFGIFGNAVTAAMSPVMHNAAFRFCGMPHHYRTFQSSSLSDMEHFVREPTFGGASISAPFKKAIIATLDYVSPEARAIGAVNTLIPLRAPMLQSLVDGNRQGPVVALFGDNTDWIGIHSCINRNLSPINAVRRRTTALVLGAGGMAQAAVYALIRLGVKTIFIYNRTLTNAEKLVRQFNGQSFSVHNMDLMADNTEERRPGTDSSSSSNSNSGSGSVTPPIRKTGPVAVHAMPSIDEPWPAGIAPPTIVVACIARVSKDGVPVPDIVLPESWLSSPTGGVVVELAYNPIDTPLIQQVRSLSRQGWIPVHGLQVLPEQGFAQFELFTGRKAPEFTMRAEVRKCAESTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC6</accession>
    <name>A0ABR3YIC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Extracellular mutant protein 11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029178">
        <property type="entry name" value="Ecm11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15463">
        <property type="entry name" value="ECM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Extracellular mutant protein 11 C-terminal" evidence="2">
        <location>
            <begin position="427"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="567" mass="62398" checksum="198C5D47DB1A2EE1" modified="2025-10-08" version="1">MLRYMRSSEPKANGNGNGNGVNGSNAAGTSNNAAGINANGVPGGSPKLPSSQSGTQYPPQTIHAPLPLSARQQLAEAAKIPVPTPLRGATPNHQTNGGLASASPSPKQSQQQQQQPSTQDQPQRQPSFQRTRSNSDQNRPPPVSSELSQQQQQQQIWEESSINSMFAESVTTTTRPPPRSANLGRYDSPFPQQRAQHHYERTTAGDRGTEEQTAPLLVGDRGVLRILPTNANGDTVAHADDPYVDRSPYGSPSRHMPVLKHSKYALRDARGATRRSSFSERQPHGNLDETNGGSPERRIHQRSESIPKLNGAAMAGGGVGLDRDLGTQRSTFSRDVDAPLGRTPARPETDDGSDLPSQGDEATNQRTPRQNRSSPPGPPPQQPPPAVPQLLQQKRVLQESSLPRVGGGGGSRREKKSSSRKRRHSPDYDDSMLHAMSYSELRDEPFDHDPARMAIHQPPTAPAKLATIEDRLVHFKGKDANSQHHFFTEMSVTEWDECGDWFLTQFAELSNKIREKRQAKRRRMADFEDEITEREKTVRHKAESIERTLGDLRHEGEGMMRGKVVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIW7</accession>
    <name>A0ABR3YIW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009657</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="365"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="495" mass="53857" checksum="AC0A18AA16C70C1A" modified="2025-10-08" version="1">MTAKSASRKRKAQAQGKADQKPSKVSRPISPPSDTPPEPTSLQSVTSTEELEITVETLRALAAHPAVIKGKQCRELRGAVHEFRQACTTGVNAAGTNLTARVSAALADGKYMDARVLLAEMRLRGEELKLGALCRWVRDLDIISGLSTAPDHRDAVAAERSAEAKERLLVVDAILRATGPIDINPEALSRYAKSPIGTPAILTQDIWDLRPAKEREQVYASVLDKSILKHAPNPDVIPDALPIIETTEGAQRKPPNHHPAIVYTSAEGAIPLAPKAPATIAYTPHPVVPRLGVATDVLTPDECKAIIAAGESVGFLPDAPVREDGDVSILAHNFYWVIDPQFHDLLWSRISQFVPSVLGGRVARGINRRFRVYRYVPGAEYRCHIDGAWPPSGIRPDRTYVYDDSPEGKKQSSLFTFLVYLNDEFEGGETTFFLPGAVEGTLNAYPVRPVMGGVAIFPHGETRGALLHEGTGVRKGAKYVIRTDVEYDVEPTESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIX2</accession>
    <name>A0ABR3YIX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13315">
        <property type="entry name" value="PH_Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028258">
        <property type="entry name" value="Sec3-PIP2_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048628">
        <property type="entry name" value="Sec3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019160">
        <property type="entry name" value="Sec3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15277">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20654">
        <property type="entry name" value="Sec3_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09763">
        <property type="entry name" value="Sec3_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01313">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec3 PIP2-binding N-terminal" evidence="6">
        <location>
            <begin position="65"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="477"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="542"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1034"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="195"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1057"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1495" mass="162055" checksum="94752BEAE419070E" modified="2025-10-08" version="1">MAMQGGRDMGRAERFEDEKRRIIDSCFNKKDDDGSVIETYITHIKIQEYSSHPTSPPPPQNRTPSSEKHRVIIVAVRKSGRVRVHKSKENPNGTFSIGKTWDLNDLSAIESYTAANVSPDFRAWAGNVGFLITLGKPYYWQAQTDKEKRFFIASLLKIYGKYSGGKVPLLTGFDPYELEQIQGGAQQRRPPPPSQLQTATTSSTPASSISTSRPPSQPQNSQNQPSQAPPQPTPPPPLSAREPMSAASSSGNYGSMGSADFRNQRSAMLANGAASPATSIDSGRSANQAALRRLAGSNKSQESVAASMTARSDDGNNSLPPRSRNGPINGASSSLADSPAIAPDGSSSNKPPPERKRPPMDPSRPQGLADDGLVPAPLMSSTRSRDGGPIGPGGPGGPGSNVVPPPRSSNRSSPFQDGSSSARTTDMVPPPLRSPMNGSSYGASAASTPPTQPLPQPPQAADLTVAATTAAVAMGTTAVSAAASPTPSAATTVSQPAESVPAPPPIPAEPEDNRPGLGPMIKKRSKGDIANAFWKAATAANAFKPRPGGAGDRLRQAQTKAVEGPDGITGVVPAPPRPVSIEKPKEPAPLAAATTTTTAPEVPPKTPQRSSVRSIPEVKITVPNSSRPSSMQSSTVKEVTPATKPVSSAAAAAAAAAADLGLRKSVIVGNDAKYLATLGVDPTIMDKRGAEFAKWLDYFGWVPGDHMRSVNMDDLKIDLDRELNRAQAGGWLSRFQEEDDRVEAIKKGIDVAMDECEELDNLLTLYSVELSTLSDDIAYIEAQGQGLQVQAANQKLLRKELESLLDTCAITNKDLEALRIAPLETTNGIEEIETALVTLYKAMSKIDPKKMGGGGGGGANDALAQLEQALSGDSGGALNTDFGQMRVVREKKEMYSAESDTFMRRLVIFMATEFDQAFAQTRKAMEGALAKKVDPRNHDVGRDLLWKYSPLILYAREADLANWNRIIQIYEDKSHPVYKSEFRDLLMVWKKNARKASSDDSEILFTSLQEKKEEGIATTARKLTVKRSQTLARSLRSPLGDNSSNSGSGSGSGKGDGPARNHLEKTSGDGRNHPYEVFSSVLDELLPLAQMEQNFIIDMFHATTLQQADFTDVVAASRPAERRGADLRRYRPMEPDRELARRVTRAMENVFSFLEQDLQHLIDWVLSTEALQGIGVMATLERKMAEVQQSNQEFLNNLLQKLHSTLEVRFRKFVDEQIRAIEETKVKIKKRKGVIGFMRIFPIFSAAVENMLADIDPNLAVRRTVDHEYDRILRSMFDSLKVIARENPTMTVAAAGSADPEDKEALNFHILLIENMNHYLEDVDNPRGLAVLDQWKEAAAAELTEHMGLYLNAVMRRPLGRLLEHLENVEAQLASGRSASAVANQPSNSKTMFNKVLGSYDAKEVRKGIETLRKRVEKHFSSADDEQASTLATLSSSSPTTNNSLVNYVVRECEAFYTDVENRIGSITTNVYGGDVLYEWPRAEVKQAFAISGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE6</accession>
    <name>A0ABR3YLE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045555079" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="45"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="262" mass="27829" checksum="336F9C57E141F48B" modified="2025-10-08" version="1">MLSNTNLLLALAASSLVSASPIASTLTQRTPSTDAVETAASVSTSTGFQLVAVVTDPFNALATRVQNMVLQAYHAGASYRMPVLTKPDAENPGRIFYFDRPPQNSSSILLTDSSGETPANSTSNPSISFGLAVQSPDDFIVPEYPQEHGSWFYAGSGDATPVSPANMHTPYGGLYLLNEQGSGTFMACNRTIPYYNLENGITLEYLYDSDASAPNEKPSVPENCVPIRLVFVCADLPDVPAGSQSSHANAQPVSCYTNMEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLG9</accession>
    <name>A0ABR3YLG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046894604" evidence="3">
        <location>
            <begin position="49"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="629" mass="63828" checksum="5DD0E04488480FDD" modified="2025-10-08" version="1">MPLRRSAPTIGAPASSSASRPSSLFTSTTPTWTVFLLVLLAILPACHAAFAGADIDGRDVFLAGDIDNSLAGVGLSPRYFLDGFAPPIARRDDSSNCAAGYHSCLDINSTLCCANDRYCLVDPTTLQAACCSIGLTCGSPCNETQYECNATTTKTVTQTKTDLVISGTATLPLTTPATDVVTGVDTAITKITTVITTTSVYSACCARRCQGTSQFQCASSFGNGCCNFGQTCASNSQCFSTAPASTSKSADASDTAGLVSALPNGCTTSQIACPSSLGGGCCALGHTCTVVSSTIFCASATGASTSGVTTADKSSSSLSAGAKAGIAIGAVVGAGALAGAAVWACMRSRNAKRTSIRRDSSLPPASFGTHEYDDLQSQPHNDPQMHNPQLYQQGMIDGALVGGGMSAAASSPAARSWRRPLAFRRNTASTGVGGNEVAHSSSGAGPVGGMGTPGLPTGSESDARLPGLTQDYFGPNAVPGPYTVPVWATTPGGNAGVGGVPMQPHGPHDIVAPVEIDSRQRIVAEMGDVNNVGRLDETDEHNNEKDAAAVQASPYVAVAPPAAAAEPAEHFELYGSEVATPYTQQTVSPNERPGDHTAVTPIAEGGDGAEPVVSPMENTDLPGGGPRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX9</accession>
    <name>A0ABR3YLX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sfi1 spindle body domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013665">
        <property type="entry name" value="Sfi1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08457">
        <property type="entry name" value="Sfi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sfi1 spindle body" evidence="2">
        <location>
            <begin position="629"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1364"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1607"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="943"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1381"/>
            <end position="1398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1680" mass="187336" checksum="82759A0D5D7C9EE3" modified="2025-10-08" version="1">MPSHAPLSSRDGRIRSSSLRQGSEFYYSNEDIELLHQVVALGQDILPTLPKRDKLPTTALFRAADIVFPRHGLDPDGEDKLSRIIFLVGGMRSTDNLLDRFRTVLGRMGIELEYVPDSSDLDADDGGDENDDINDDDAMDDEENKGRIVHHPNHHRRHSHIHASPPSPHPPSPPLSVHSVAPSSAGGLTSHSGVFPVAPHVTGRRRRNSDSVAEFVVAAGASRLDRGRQEHQHAQIGIGRQSHRSPARQQQHRQHHRRRSDSLAPPLVNYKDYFGTADERRPPPQLPPQPQLLPSLPLQQQQTRPRPSHTSRPIDPWLSQVPRYLTAPEEVEYTQEHVIPHKGDDLDRTRNVEESEGDFDYDDDDDDDDEAPGVDQYTQSLDLLSAAAARRHGHYNLPQQQQQHPHNIPPEIIGSRSTAHLSHNHNYQHHQQLPYRTRPFSQNVPHSAQPQLGTGPDRYTHSQHSSMQPAGSWTEPQSPRSRLSSVATDYEGFQAASDTTVQEELEAGPPPRVDPFIMAKVADTFFMRFAFLGGLAIDVWRTTSAAHQEQERYAAQMDRELSVSEALLMWSSVAGTHIDEMTQKTRQLTAPIEQQAITTEKDQLDEVDQQHVDDIEAEDDQDDHDDEAAVQYREKQEERERLMRRAARVYTITTMFNAVCHWHAMAKEEAGRTKVARRHLLRRKVFGAWREQTASDTVKADCFALSWAVKRWTAALHRGPKENTKLSVQFYNRDLVTVTFWTWLRAHQERTADAWAIDRLKKQAVEDWCQSTIAAAGAKDKAMSLEQKSLLSTAIIKWSEQAQSQALTLLSIEEQENETYMKAALQDWAKEAFCQEQLRALQAANKTRTKAAVLDFWRESAAEAQHRATQLDLDIAEEYAAHWHRETRLAIFRAVYEYDLKIDAVQSWVLAEKLAFLIRYRDEQLLWKTCLTIKANFGTDPDQQGQQGQQGEQQREDELARTADRLDKANAFAGLVSVFREQNERRSAWKQIAEYLDQEAMANKALGLWTAATAEHDEMNEIARRGAFYVGTANALSDWPVYAKNVRKERLRSTYYTFRREVKRKTAFDCIAAWRDAALRLGSEEHGDGAYAAADQLRYEHEAYTVFTTLNHWILETNDCLFQQTVAAEADAEVYLSRWRLQLADCEELGSAAAEHDTVTQLAGRWDDWELQAVQARGREHTATALLEKNERRLGRRVLAVWQQELADQLYLDSVGPDNDLRRSFAASTAPRWQGEEATSIGPGSSLWRLGASLSSPLIGRSDGPRPSPSYAPGHDGREDRPARVVQVGARPASALFHPVTETPVATTKQPFYSRGPYGAISGGYSVPAPGTAPAETAMTVNTAPQPSSAGPNQIRRLHRSATAAPFRQQMQKQQQATPFRSSSSPETAATAPARASSYNHRLLQRRLQSAARLADSVQLGPMSEFDEVEAAAEQGEVDDDPLALLDYADADVSSEGDDDLGLGAGSSSLLPERRNFQMLSSNTPTRHLFRPGSSELTAIAAPSVTRAPPQIRPAALPAQAHSNFRSSIAVTGGTGMSQSVGGLPAPADPRLSRFRPSRSLLRKSAVVGAAAASGTTVFPPSSSFDPITTTPMGPLPSPFERRLRAAYGDRSGRDNDNNNNLVDEEREDYSVGQRASLATATPIRQLPLRASFAASTAPATGRTGARVTFADVDQDKIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM19</accession>
    <name>A0ABR3YM19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="100" mass="11260" checksum="AC805F1AF79D1FFF" modified="2025-10-08" version="1" fragment="single">PPRYLTYRFRLVFDGYGYLIQNITAPLVAGKCGSYLLLTPLPPVPPTYYDYTVATINNEGRRTHATLKKVHAARDVLETIAIPSVGDKARDLAFTVRNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM34</accession>
    <name>A0ABR3YM34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromatin assembly factor-I (CAF-I) p90 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RLF2</name>
        <name evidence="8" type="ORF">Sste5346_009001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048800">
        <property type="entry name" value="Cac1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022043">
        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21796">
        <property type="entry name" value="Cac1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12253">
        <property type="entry name" value="CAF1A_dimeriz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="6">
        <location>
            <begin position="463"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Chromatin assembly factor 1 subunit Cac1-like C-terminal" evidence="7">
        <location>
            <begin position="691"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="510"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="606"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="649"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="612"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="747" mass="80559" checksum="269414F17DC3C772" modified="2025-10-08" version="1">MSPNIQDGGTAATPSKKRTLMDFLGGANAQKAAALTTKPATPSKLQLVTDADNLAALEKEKQEQKAQNGDGGDPTSPIDLMSIDSPLSEMSDGPLSLLTDDAGSSTPARGSTSPNATPCKSSAGASPQVVITIDATPPPGLTAAMATTQPPAAKRKRLTPSEREEKARADAARKLEKEKADAARKLEKEKAELVKKQEKEKVEAAKKQERDEKTAAAEAKKKAIAEEKEKKRKQKEDEDRKKNEEKEKKRKEKEDEERKIQEAKEKKERSQLRLNSFFKTPAGSNSTSTSTATASGSLLPGSSPLKPVAVRGSSASPRKPTALSNATASDTSTEPDTMVVEVSEYDRIFKPFFVKENVIMATDLYGMDDETKEAKSRILDEFLAGSRGEFAPTKPFSVTAAVDYFHLPGKPEQARGRNRPTVRKIMNMLDPDAIYGGLQSGLDGASDAQTKLALNLLKSVPMKYLFFREDVRPAYFGTVTSQPPTARLSKLARNPLAKTVLPLDYDYDSEAEWVDDGDGEDVDDLDDDEEELDEDGEMSDFLDDSEDAMPLRPAFSGGMEPESTGVCWENERRKACKPELDNFRMEFILDHDGPIDPFSTQYWETKEPAPAPSAATTTTTDTPNKSMAPPPTPADAFAALGAGAAAAGTTSKSDASASATTSTTAAPTAAEVDKPADPKKAGVAAEFVPDLKKSILQYAKLSKLGLVEILSVEFVGKCTKGQIKNSLEALAERTGTGHNKTWKLKAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN58</accession>
    <name>A0ABR3YN58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009542">
        <property type="entry name" value="Spc1/SPCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06645">
        <property type="entry name" value="SPC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="109" mass="11827" checksum="0E68E3D25ADF171B" modified="2025-10-08" version="1">MADQLLDQIRDVAEGQIDFEGQRLCDTLATILLCAVGAITFVVGYILQDIKLAVYIALGGTALTFVAIIPPWPFFNKNPVKWLPVGRGAASSQNISIPQTVVIDEKAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN73</accession>
    <name>A0ABR3YN73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="444"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="587" mass="63910" checksum="67C7874E3CCD0F48" modified="2025-10-08" version="1">MNSDHSSQRSLPMTPPRRASQQSTTSTPTPPSTGRHYQQKLQTPPNHMTLPLSLPMSTMAAMTMSSMPLSMPLTMPLALPTDATTTTATQSHDVFGEHMYYGQESGSASNSNNNGNNSHAEVANMGMDPGLDSAMDMNLGMELGMDMTLGMDMDDVDMGVIMYMSMPEDNHMTYTGFSYDQTSSCNAQASSSSHGSTATNANHNSARQSTPPSMYLFNEPGMSLDNTTASPYGDPLTGYSTSSTTGGFPFNTSSSMAPSTLSSSYPSIYPIPQAATAAMEPTGESTFTTSMSLPTTSTLNSIAMSSPPLTRSRARHGRTYSTRSASDPIPSTKGRGNGHCRHTRGVSFDSADDDYFEDCCDVDDNNNDTNDTPANQQHQLRPGPNINGPPPIDPSDWRARLRYCEQAKHKASLDASLVRLLELSEGLDDYELEARRAANLRFDRVREQRLKDRNNEAAKRSRQRKVARIEAAEQSIASLRRERAQLAGEVQQLRRQLAAATSPGRDAKVHKGGRQSTTPQRRRSSEHSSGHSGHSGRLSNSPNGRGKHSRRNSDESAIDDEEDEDSEDEDHIDRPRHGNSIVVGMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNG5</accession>
    <name>A0ABR3YNG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018555">
        <property type="entry name" value="C630.06c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09428">
        <property type="entry name" value="DUF2011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="382" mass="41070" checksum="660DDFFD1CB4D8A6" modified="2025-10-08" version="1">MASIMNHTRAVRREDLAREADDQTGGNPSRRRDDGFEYEEALAARAALDAYMKDTLGLQFDVPPPRSAPPKPAASVAEEKKSEKDNGNKDDESDESKDSSDDEAKDNESEYKDAKSQNTGGATEFAFRLFSGSGKAAATAQNTDDSSAPNSSTDTTAVPVPIVLLDDGDGSDLLGPGGILNSPRPLSFYLAGEPTPEVLEQYAQATVSGEDIVKASRETRAWGWEVPWRARTVLKASSKTAMRDLLANALSPDAAAALPENLPVAIASATNALPVWAASSQSPEPTNPLPLLRLPDDTLATKHSRPGKRRRIILRKREQERQEKAAKAAAQAQSKEEHLSEKKKRLNRIKKLRRREKKRAEKGAGGDEGGDGGDDSGDSGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPL0</accession>
    <name>A0ABR3YPL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="50725" checksum="0E363F80A59EF057" modified="2025-10-08" version="1">MTKHHYLAKVVFEAPGAGDDDDLHQTTVRCNGRLFNINMAAAYIHDSPAILARFQRFLLAQREFVYEEDPVTYEGPSAEDERNSFHQWLITTFQPVFRAHAPDVLPSFDPDAIRSGTARPLLAEYMFPQVFECRLEAQRDKARPLCVGKQADWIPPVNRIPADLLADLDRLRVPRYAPSEIAVAFENPGDALREMPNRVLVDVDCSGYPDTACHLKLFLGGFEGSLVTELRGHLRVLDAQLSAHVRVIRLVGIVWLEEYADASDKDKDGNPVTYPESLLGPVGGLLLTYVSEGWDGLLTSRVWGSPPAMRRQWADQVRETVTTLHKAGVMWGDAKPENVMVDGNNNAWLIDLGGGFTEGWVDEDKAGTKEGDLQGVAKIEEYLMDNDRFEMTSEDEQEDKYEDKRESEREFRELRGDYEDREDEHEGDSRDLGREERSMSKRRKIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPR7</accession>
    <name>A0ABR3YPR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent D-xylose reductase (XR)</fullName>
            <ecNumber evidence="3">1.1.1.307</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">XYL1</name>
        <name evidence="3" type="ORF">Sste5346_008583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.307" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="326" mass="36658" checksum="F485BF120FDDAA9A" modified="2025-10-08" version="1">MAQSTVKLASGYEMPLVGFGLWKVPAAQAADTVYNAIKAGYRCFDGAYDYQNEKEAGEGVRRAIKEGLVRREDIFVMTKLWNNYHRREHALAMAKAQNEAWGLGYIDLYLIHFPVALKYIETEKRRYPAWWMDDAGTVEPDNVPIRETWEALETVVDMGVAHAIGVSNFQAQSLYDIQRYARHPISALQIEHHPYLAQLDLVALAQEHNIVVTAYSSFGPQSFMELPGIFSKRAKDTEPLLETAVVKSLAGKHGKTPAQILLRWATQRGVAVIPKSNNAARLAQNLDVLSFDLTLDELESISGLDKGLRFNDPGFYLPNYPLRIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQG7</accession>
    <name>A0ABR3YQG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="99"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="367" mass="38884" checksum="72AD63D776E47A25" modified="2025-10-08" version="1">MSASAASSSAAGAGAHGAYGAAPGSSSGTNGAKPVADVGFRPQANMAVVPPRKEDLQKSYASIVGDDHNPAGWYGSMINTLGSCIGSLGAIPCCICCPNPYKSVGQGNVGLVTKFGRFYKAVDPGLVKINPLSERLIQVDVKIQIVEVPKQVCMTKDNVTVHLTSVIYYHIVSPHKAAFGIANVRQALIERTQTTLRHVVGARVLQDVIERREEIAQSIGEIIEDVAAGWGVQVESMLIKDIIFSQELQESLSMAAQSTRLGESKIIAAKAEVESAKLMRQAADILSSAPAMQIRYLEAMQAMAKSANSKVIFLPATNQTMPGSPAFDAAMQAPKVGEASEPSHFSEFAGQDHGFQSAVNARVIEQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR38</accession>
    <name>A0ABR3YR38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008325</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="32"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="358" mass="39758" checksum="AA0E87FBEBAAC503" modified="2025-10-08" version="1">MGSVDTTPQLRVQPLTKGSSIDHWEYVDVSPIIGREYPTASLKQMIDAPNADEQLRDLAITICERGVVFFRAAQDDLSIDEQKDITDRLGKLTGRPAENGLHVHPLYNDPNNIPMANGKTDRNIYVINSEAQKKMYATMKNRPAATEPRDLGREWHSDSLFENCPSDFSFLRMESTPPAGGDTLWVSGYELYDRLSPPFRAFFETLTATCAQPVFKSACEAGGYDVMTPRGAPQNVDYSFEPVHPVVRTHPVTGWKSLFAGVGLHVSRINGVSSYEDQMLREYCLRLITRNHDCIARMHWTRGACAIWSNECTLHAATPDTHLVEGVRTGVRASGIGGVPYLDPASTGRRAALGLPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRC2</accession>
    <name>A0ABR3YRC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Catalase-peroxidase</fullName>
            <shortName evidence="8">CP</shortName>
            <ecNumber evidence="8 9">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">katG</name>
        <name evidence="11" type="ORF">Sste5346_008210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8 9">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>H2O2 + AH2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="8 9"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00649">
        <property type="entry name" value="catalase_peroxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08200">
        <property type="entry name" value="catalase_peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011635">
        <property type="entry name" value="PRK15061.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555:SF0">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="HYDROPEROXIDASE I, BIFUNCTIONAL CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="5 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 8 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="10">
        <location>
            <begin position="125"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with Met-250)" evidence="8">
        <location>
            <begin position="91"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)" evidence="8">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="771" mass="83420" checksum="744B1AA564C13C28" modified="2025-10-08" version="1">MAEGKCPVVHNVAGGGTKNTDWWPGQLRLNILRQQNEVSNPLDRDADYRKAFESLDYAQLKKDIAAVMTDSQPWWPADFGHYGGLFVRMAWHSAGTYRAFDGRGGGGQGQQRFAPLNSWPDNVSLDKARRLLWPVKQKYGQKISWADLLLLTGNVALETMGFKTFGFSGGRADTWEPDQATYWGGEHSWLGNEVRYAGADPKDPKAHAEGLETPVAAAHMGLIYVNPEGPNGNPDPIAAAEDIRVTFGRMAMNDEETVALIAGGHSFGKTHGAAGGDHQGPEPEAAGLEAQGLGWKGSYGSGVGKDAITSGLEVIWTKTPTQWSNQFFEYLFKYEWELTKSPGGANQWVAKTDDLIIPDAFDPSKKLKPRMLTTDLSLRFDPVYEKISRRFLANPDEFADAFARAWFKLLHRDLGPASLYIGPEVPKEQLLWQDNVPAVTTPAIDAADVASLKKAILASGVAPNKLISAAWASASTFRGSDKRGGANGGRIRLAPQKDWAVNNPAQLAEVLKALEGVQADFNKSAAGGKQVSIADLVVLGGSAAVEAAASQFAGQAVTVPFLPGRGDATLEQTDVESAAFLEPQADGFRNYGKSTPRARTEELLVDRAQLLGLTPPELTVLVGGLRVLDVNFDGSRTGVFTDRPGVLSNDFFVNLLDMATAWKPASSDAHPETYVGYDRASGKERWTASRVDLVFGSQAELRALSEVYASADGAAKFVKDFIAAWTKVMNADRFDVKSTIDGTTLTNRAKRAADETASEAAAEYKRGRAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRX4</accession>
    <name>A0ABR3YRX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007886</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="29"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="569" mass="60249" checksum="3B444DE5E77E4EE1" modified="2025-10-08" version="1">MGRTAQPTAAELALHEQTNLLPRGKLLVVLATLSITLLVTFIDQNGISVALPTIAADIHAEDTVSWAGTASLIGNTTFQMLYGRLSDLFGRKAVYLGAVALLAGADLGCGLVHTPAAFYICRALAGIGGGGITNLSMIIVSDVVTLEQRGRYQGIIGAMVGLGNVGGPFLAAALIERAHDWRAFFYMLAPLAALTGVLASFLLPPSSKGRAPWRESFKKIDYWGMLSSSVAVVFLLIPISGGGNYYEWNSPMVIAMLVIGALALPLFLLVEWKLAKLPMMPLSMFTSPAVAVMMAQNVLFGAVYQSCLYYIPLYLQNAHQFTPIGSAAICSALVGFQTALSILSGQYISRRKRYGEVIWAGFGLWTLGAGLCLLFTRDTPAGVLIVPLMLVGAGVGCIFQPVLVALQAHVAPARRAVITSNRNFFRCAGGAVGLAVSAAVLQATLRKKLPPAYADSIASRPYAVPDLTSLPLADADAILDTYMAASHAVFTLLVPLIGLCFIGCVLIRDRGLQGPKPGTPVPVINAVRESSQERAASLDASSSEDSPAVVDIEKNAAREELTQADVREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSP1</accession>
    <name>A0ABR3YSP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6 18">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 18">Alpha-IPM isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 18">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">LEU1</name>
        <name evidence="22" type="ORF">Sste5346_007663</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 18">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6 18"/>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012235">
        <property type="entry name" value="3-IsopropMal_deHydtase_ssu/lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002458">
        <property type="entry name" value="PRK01641.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004016">
        <property type="entry name" value="PRK05478.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009116">
        <property type="entry name" value="PRK12466.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF9">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001418">
        <property type="entry name" value="ACN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="14 18 22" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="20">
        <location>
            <begin position="13"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="21">
        <location>
            <begin position="545"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="492"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1891400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="780" mass="85099" checksum="965D0B6F7DBFC913" modified="2025-10-08" version="1">MPGVESAPRTLYDKVLGDHIVDEKLDGTLLLYIDRHLVHEVTSPQAFEGLKNAGRKVRRPDCTLATTDHNIPTSSRKTLKDIASFIQEDDSRTQCVTLEENVKDFGITYFGLGDKRQGIVHVIGPEQGFTLPATTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLITKRSKNMRVQVDGELAPGVSSKDVVLHVIGKIGTAGGTGAVIEFCGSVIRNLSMEARMSICNMSIEGGARAGMVAPDEITFEYLKGRPLAPKFGSEEWNRATAYWKSLQSDPGAKYDIDVFIDGKDIIPTVTWGTSPEDVVPINGVVPDPETFATESKKATGRRMLEYMGLTAGTPMEEIPIDKVFIGSCTNSRIEDLRAAASVVKGRKIAANVKRAMVVPGSGLVKTQAEEEGLDKVFVDAGFEWREAGCSMCLGMNPDILSPKERCASTSNRNFEGRQGSQGRTHLMSPVMAAAAAIVGKLADVRKLTQYTASPHIDAFRANTTESTGKPHVDERVEEDDAEKEHITDQPEDNAPHTNTSVAGHGSSAGLPTFTVHRGIAAVMERTNVDTDAIIPKQFLKTIKRTGLGKALFNDWRYLPNGEENPNFELNKEPYRNAKILVVTGPNFGCGSSREHAPWALNDFGIRSVIAPSFADIFFNNSFKNGMLMIPIKNPADIEAIAVEGRAGREVEIDLPNQLIKTAEGKTICSFDVEEFRKHCLVNGLDDIGLTMQMEDKIATFEKKMTRDTPWLDGKAYLKRGRNGQLLAKAIPVPKTNRGEELKEPLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTG7</accession>
    <name>A0ABR3YTG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cwf16</name>
        <name evidence="11" type="ORF">Sste5346_007635</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="223"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="121"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="313" mass="35256" checksum="EBA50D1687AD800A" modified="2025-10-08" version="1">MSERKVLSKYYPPDFDPSALARKSSNKKKNGQPAGPAMQTVRLMAPMSMRCTRCGEYIYKGRKFNARKETPLDEKYLGIQVYRFYIRCTRCSGEIIFKTDPKNQDYTLVSGAKRNVEAWRHATQEEQEETDEQRLDRLEAEEAEANGEAALEQNRMEELEAKTLEAKREMEVADALDEIRTRNARIARADHREHLETVALQARPAGEQERLWQQELEDAEAARAAFAAAAKGIEEEAEDDNDSDSDSDGQPAWLSKTGSSKPKMTASSSSATPKPPTPPVVEESVPVPSFKRQVKKKKDHALLLGIKKKPSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU81</accession>
    <name>A0ABR3YU81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="16"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="45638" checksum="48514EE09ACB05D7" modified="2025-10-08" version="1">MSELDEILARYTHPETGSIHGASFVAVDAQGNDLYRGAFGRTKVDPANPESKPLSLNTVTWIASQSKLTTSVAVMQAVEQGLVGLDDDVRKIVPALRDIQVLTGFDDDKNQPILEDLTGPLTLRQLISHTSGFAYDARHPLLIKYSKWAGRTAHMFDGSIAGQTHPLVFQPGTSWIYGPGLDWAGHVVEKLTGDTFDAFQQKNIWEPLGATKTTFFPTKRGITAGDLHELALRTPGKGTKQGLTAGASPWPMDCQDSLGGAGLYSTASDYIRLLKALVGGGSPILSAASLDEMFRPQVSAASDADMRTFINSTGPKNSKAWLWTDDDTKHWNDYMKVRSCLCGLVNSEDVVGKNDARRRSKGTVNWDGLPNLLWFVDRESGVAATFFTQIMPMDDAEARKLCTELEEALYRLVEKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUC1</accession>
    <name>A0ABR3YUC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007699</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF33">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="392" mass="43572" checksum="C8B7D7A1C26E2A3E" modified="2025-10-08" version="1">MAKRPNFFLIVADDLGFSDVGAFGGEIHTPNLDALAASQAGVRLTNFHTASMCSPTRSMLLSGTDNYIAGLGQMEFRSRDLNPPMPWGNGYYTCMSGKWHLGLTRERAPHARGFDRSFALLSGGSAHYLYQPTHPDGTPVFAHWAPLYYEDDKQVDVKTLPQDYTSDSFVSRMAPQASIRKYRGIYNDGPDALRERRQQRQIELGLLPADAEAHPVVTDTIEWDDMTDVGQKWSSRTMEVFAGIVDRMDENIGRVIERIKSLGEWDNTFVLFMSDNGAERAVIEAIPMTGELDNLGNRDSFIWYGPRWAQTSTAPSRMHKGYVTEGGIRCPAIVHYRPLAAARTAGGEVTDAFATVMDILPTILDLAGVSHPGPTFRGREVVLVRAHRGFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUG8</accession>
    <name>A0ABR3YUG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007487</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="375"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="786"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="829" mass="88449" checksum="4BAE86E72CD2A3BD" modified="2025-10-08" version="1">MSAAVGETKTAKYPTKLRRNYPRSRNGCLTCRQRKKKCDETRPQCVGCTRNKLSCVWPARTKTAGVGSNGAGASASGDSTASTGTSAHPCPLISSSNLTLYQHKSRWQTYLPSLAAWEGVEGCSVNLNPAYDEAGYRRDVVAVGLTTAGTTGTTGTPATTSATIATDSSSAGIDDADSVQPQSSSNHNTDMDDYATTTTTTADDDDGFNMYDDDEMSHQDDEYSRHLDGDHEDNAEEEDEDAILAAWSPVLGSFTVDAVPPPPPKKSAIAAYRRQQSQYQYQHQEQYRQQRRRTSSAPRPSYPIQRRRVAAMTPLSASMLRHYIVEAAPTLATCRAASNPYIAAFLPLAYTDDLVMHCVLAIGGAHLSNRLTKPCATEGDSEGNGSSTATGSSTIPPPPSTTATTANAAAGSTLAPYTAPDVAAAALHDATTRHYACVLRSLRSVLRDLQPSDTAQVLRVLAILMLLTTYECLSWNILGGSVFTHLRASRQLIGWLRSDERNATLSPDERSLLGALLEIYAYQVLANRVCPDGSIQGRSAAGDEDTTIHDDEDFVADPSLLQDQECFGLLFSGLHGLFALIPPVSRLAAAAVQPKSTNTAQPSSSASTLSSLFHDTTATGTSSLTIAAQVAALRNRALAWQLPAAFLARATGDQERIWQRAIGEVYRHGILIYLETIKVPGADDTAPTTSTTGTGTGNAATFQRHIHAIGEAVLGADLVASRFATILLWPLLIAGSILAHPDERVFLAEGLRASPQATWSSIRAADLLEQLWARRDGVVSGRALTSDKAATGGGNSNTSGVSHSNSRQYYGPHGIAQIMRETNVNLCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUS6</accession>
    <name>A0ABR3YUS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-mRNA-splicing factor PRP46</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pre-mRNA-processing protein 46</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PRP46</name>
        <name evidence="7" type="ORF">Sste5346_007553</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the WD repeat PRL1/PRL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045241">
        <property type="entry name" value="Prp46/PLRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923:SF0">
        <property type="entry name" value="PLEIOTROPIC REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923">
        <property type="entry name" value="WD40 REPEAT PROTEINPRL1/PRL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="1 4 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="196"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="238"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="280"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="405"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="55089" checksum="A7CA98585D20A1F4" modified="2025-10-08" version="1">MAAQVADGHVPAETADLSNLIKRNAQVSKSIYFDGSSATASGARKRLRLDPTTGSDPDLNEESLSLRLNAEYADVQTLPEALATKQAAAAGAAVARKKAQRKKTDDQADGEEAATRKMIEGIQESGKATKNGTAGTAQTTALMQIRRPPGAGTGTGAGAGPGTARGQPGQQLIRAQDLHTQPRPDWHPPWKLMRVISGHLGWVRSLAVEPGNKWFASGAGDRTIKIWDLVSGQLRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPTLDVLVTGGRDGVARVWDMRTRSNIHVLAGHTGTISDVRCQEADPQVITGSLDSTVRLWDLAAGKSSGVLTHHKKGVRALTVHPTEFTFASASAGSIKQWKCPEGAFMQNFEGHNAILNTMSVNADNVLFSGADNGSMSFWDWKTGYRFQSLDTIAQPGSLDAESGIMSSTFDRSGLRMICGEADKTIKIWKQDEQATPETHPIDWQPAMSRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVT3</accession>
    <name>A0ABR3YVT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1892001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="514"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="535" mass="55537" checksum="A4B2AB48B712866B" modified="2025-10-08" version="1">MEHAIPIGDEEIDIAVVCTDCYITGQLTTELTVIPSNHTTVNLSTIAHTFASDVVNITDTVVNDVEEIVKNTTEALFDKVPSLDTFETILHNITRPTVDVDFGLSDLVAVPEYQFALTLDELDLFVQTQMTVSGAATYTLNLYTSESPIGLKKGNDLELGIVLTADLILSAYGSLELESGFHLRMDEGLTLTVDLFGRNISEIECHGGSFEFLPVTVNSATVSLQAILRVGVHAGIVMSSKGLTVEGVSIATYSAGLETIAYADVANLTINVAAGSAITGGDKTTSVDSISNVDLTTDTCDGDVFVEGIFNFDIGASAGASLEIGDFLSWGVHPETMLPVFYTTVTQCVGQSSTSTVTATTSPTTKVAARAATTVAPTASSFSSNESRETTVVSSEFVYTAIACRSAGLINCPASLQTTAVTTATSTTTLTVDAATGWEATYPAPTDTTPITKLATFGNNVKTMDLSVSGTPVSYVPPVPTTSSASSSLGTASPTSTPGLTIGGVHLTPKQEHIVIGVTVGAGVPLIIGGIALIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW33</accession>
    <name>A0ABR3YW33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="485" mass="52747" checksum="F9115E92DBBDB8D1" modified="2025-10-08" version="1">MGQRFPLLLLDDSDEDSDSGETISSSSPSSSPASSSSPVSPSFSLSSTSSVSPVSPRSPVVPASPILDKPLPALPIELSTPSSPRINGNKVSPLAGRRISAGDNSNTLAGPRYVPSSKTAPRPRVAAQRPTLQQTLPFLRTSTTFDDILALKTSSSFNSTPLTFDEILGSSTRPEPKLIHRKPVPVFSPKVEKPAEPTASKQIITRHASQIIRPYDQTRLQSKRRAQRVVPLSVLAPSSSSANTTSPQVNRLVPYNSHHGYSLLQTLRRLLIIPTDWSPTQTLLFILQHPAVRHLALPFHLSSSPQSDYFQDLLGIPRCNALDWYGILQAIDGPIRYHAARKRSQQSLKLRAVPPTLAPCSNPRALSTNTPFSSAERDLVARWLAGGEPLFTGRMTLPAVLLRKSGKPLMSTGRTQQQSRARTPLSPLASSSVRTNDDQAASSLPPLDPATRYDISRNPRCRYHQLWTGAGKSRLSVTMLAEIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWR3</accession>
    <name>A0ABR3YWR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_007069</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1892331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="865" mass="92350" checksum="594A66935F571F3A" modified="2025-10-08" version="1">MPRKYSFESSGPDEQEPLDNSNNRHLQTTQTRQQHIELEDDHEPYYDEPPQAPVHQHQQQAQSSPRQDRQQPAYYPPSSSRTPRNPAFHPDSAYNQLAAQRQYGGAAPIRTAAIANDPADLVSPISPPAPPPHGGSRQAQDTPLPPPSNITPGADNFSESAAGGMAGIAYSVADRNPRDSGVEAMRGIQPQQSQHQQQPQQMQQPNYQGTPPPGYPQQTYQAGPYGPPQQQQQQQQYRGYNNGPYDQPEQGQLSPQMLRPAYANGGGRSVDRDSRSSLQGLGAAAYPPGVGTPGSRTPSRSPHSNFGGDVYTDNPYNRYSMHDTSLGFVNPNDIEDDGDDGLEYGRSKNARTSMLSLAGYSTKSSRSGTASGVVGPAAVGAAAIGAAAAGTAATAALAHSHSGDYAHGAGGMMGPPDGSLGDRVASSGGAHYNALNNGGSEYGGGGGSGGGGSGHVYDSGAYNNIGRSGGGSGGAPEKSEWLAQQSHSRKIWKWTIIIGIALAVIAGVVLGVVFGVVLKHKNGGGSSSNDSSGTASGDTDKNGDLGLDSPEIQKLLNNKNLHKVFPGIDYTPINTQYPDCLANPPSQNNVTRDIAVLSQLTNTIRLYGTDCNQTEMTIHAINQLKMQDTVKIWMGVWQDNNQTTNARQLAQMWDILDTYGGDPFKGVIVANEILFRQQMTTYELSTLLESVRTNMTKMSISLPVATSDLGTVWDSTLSAASDYVMANIHPFFGGVNADDAAAWTWNFWETNNGAFFKSDKSKNIISETGWPSQGGTDCGSGSTETSCPDAAVAGITEINKFLSTWVCDALTNGTEYFWFEAFDEPWKIQYDSGDENWEDHWGIMDVNRNLKSGITIPDCGGATVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWV5</accession>
    <name>A0ABR3YWV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="742" mass="81240" checksum="14BAA631DD64D886" modified="2025-10-08" version="1">MAELLEPSPATAIPPTLEESRDFFLGLPSQPRLVARTNSVTNPYTRPLYRVLGPVTDKDLAQQWRAAVSSTDDNLNHQIHNSLTSQNVRWTTFVPLIVHGLPYDDLSRNPVTYPGPDPPKAEHALFLVIGVEAQTCSWAVGHAAANDCRRILQQQFPHHDIHALVAELAVVPMSSSPVPPLLASPQPAASPTPSPAASPAASPAPDTEPTTPVHSSSQGHHALFRGFDSTFDEIVTSDNMLLYKHYLLGVMQYINSYIVPFLPFPGQVIQPVLDGDNSERERPRGSLGLYIRLQSKEKNGSPRDTIYALTCRHVAIGRIVQEDQDYKAPQPTLPIVPMVYSDSASPMSQDQPLPIPVSNPISISMAWGSNTVASEQHKSLREQADSIDTWKLEKLWLKGEISPDGEEQLGVAKRCVKRYVPDMLDILKKEFGDVDEGGYGLGAGGRIFGHVELSRRMGYMNNGYLCDWALVAVHGVSTNSGGDDDDEADEAEKGNDPDTTDTDTDSRPHPTSTRLPQPLCPRFYSNHAYIGSSQLASDRKFSVTMRDLWNDKERRIAFQELLDRRDRASFVKLEAPSSSDSKTPLDPQFVFKNGGRTASTMGVTNPIEAVVRTPFSGREFPGARVLPILTMPPSRLIMEGKNAIISSHLFSEGGDSGAAVFDKTGKVVAMIDGGVKADDQPSNVNKNTDPDSLGASAKPEQSWTWTRNALGNWPAIDITYATPMEAIFDDIREVTGLDPVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWY3</accession>
    <name>A0ABR3YWY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oleate hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010354">
        <property type="entry name" value="Oleate_hydratase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010584">
        <property type="entry name" value="PRK13977.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37417">
        <property type="entry name" value="67 KDA MYOSIN-CROSS-REACTIVE ANTIGEN FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G09970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37417:SF3">
        <property type="entry name" value="MYOSIN-CROSSREACTIVE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06100">
        <property type="entry name" value="MCRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="67206" checksum="CEDE8BA5178C25A9" modified="2025-10-08" version="1">MYYSHGNYEAFARPLKAEGVDDKKVYIVGSGLAGLSAAVFLVRDAQMPGENITIIEEGKIPGGALDGIDEPEKGFVIRGGREMEEHFECLWDMFRSIPSLEEPGASVLDEFYWLNKRDPNYSLQRATINQGQDAGTNGLFTLSETAQKEIMRLFLSARKEAENKRINEVFSADFFKSNFWLYWQTMFAFEEWHSALEMKLYLHRFVNHISGMPDFSTLKFTKFNQYESLVLPLMKYLEDHKVQFQYNTCVSDIDYTFGAADKDGVTSKRATRIHWTKDGEKGGIDIGENEYVFTIVGSLTENSDLGDQHTAARLNEGPAPAWDLWRRLAAKDPSFGHPNVFGGHIPKTKWESATVTTLDSEIPPYIQKICKRDPFSGRVVTGGIVTARDSAWRMSWTINRQPHFKKQKKDQLVIWVYGLLVEELGDYVKKPMQDCTGEEITQEWLYHIGVPVSDIPKLAAESAKCVPVMMPYVTAFFMPRAAGDRPDVVPQGSENFAFLGQFAETGTADTIFTTEYSVRTGMQAAYTLMKVDRGIPEVFASTYDVRTLLDATIAMRDHKELAKWMPERLRKFFISKLDGTEVGELLHKHHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXC9</accession>
    <name>A0ABR3YXC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Crh-like protein</fullName>
            <ecNumber evidence="16">3.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">CRH1_2</name>
        <name evidence="20" type="ORF">Sste5346_006889</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="16"/>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042972">
        <property type="term" value="F:licheninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017168">
        <property type="entry name" value="CHR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037299">
        <property type="entry name" value="Glycosidase_CRH1_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 20" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 16 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577678" description="Crh-like protein" evidence="18">
        <location>
            <begin position="19"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="19">
        <location>
            <begin position="20"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="271"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR037299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1892604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="375" mass="38757" checksum="7493DE59382167C3" modified="2025-10-08" version="1">MHFTKTAALAGLVGLASAQTYTDCNPTTNTSCPSDVGLDKSSYSVDFTAGESSDWTLSSESATYSSSTGAALTITKSGDAPTLISNFYIFFGRVSVMMRASPGTGIVSSVVLESDDLDEVDWEWIGGEDNQVQTDYFGKGNTTAYDRGTIVNLDAATQSTFRNWTLVWTEAETNWYFDGSLIRTLTYADALNGKNYPQTPMRVKVGSWAGGDSSNAEGTIEWAGGETDYSDGPFTMYVESIEIENYNPGGSYTYGDMTGDYSSIVIGASTDNSTDASSSDTTSTTSAKTSTKTSSTKTKTSAVSAASSATSVSGSSANASSNSSASASAASNGTASTSSTSSSTSIASVSGATTVISCSSIWAATALLAAAIFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXL2</accession>
    <name>A0ABR3YXL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">zrg17</name>
        <name evidence="9" type="ORF">Sste5346_007224</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a zinc transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF5">
        <property type="entry name" value="ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="280"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="559"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="683" mass="72185" checksum="8B33736E6910849E" modified="2025-10-08" version="1">MASEPEPPSFSVSLSPPAVTPAATTKGRRPRPPSILLEPTSDGEGNSVLDLSHLSGDDATAAGTTDDPFRFEVDVEVDNTDDQPLNPHDAALLRRSPSPVLDFVSPPPLSGPPRSPRSPVFSSSLGSNLLSPDSHLHSRGSNSSFLRPPNTPGSPSFNMDDTAPLSSSPANSAPINVGGAPAADNPFNFQTQYISTSPVKSNIGLRRGHRYKHSSVSAQHQIFQEPPPRPPPVLPASLPVPTLREAWTSMHRDQRIRLYWCMCHAAVAVFVFLCAAEGGDSLALTALSHLVFFDVGSAAVCVAVDVLGNFEVWRRSTIRHPFGLRRAEVLAGFAMSIFLVFGGFDLLSHDLKDCLEAATASTTASAHANAAHIRAFEVAAAADAAAAAAAANGQPHVAVPHMDIGSHHGHHHSRYIHPGTVDVAALAAFASTLVSAYGLGNHARIRRALLLLHGVAPVPRFAGKNGIIASFLGWLSSAASLLSSLGLSSVLANPFHFLTMTVSLVLLVLPLMFVAVQTWLDRLLCATIAVSMLLLGARLAVAQGLMLLMSYSGKEGSGSGTGTVSSSSSPLAQQKQQGHNHTSSLPSSSAPSSVTLEKNSPTVASVLDEIASEPQIARVEDAQFWQVHYGLCMANLRVRVAQGSGDDATLRQLRSRIARVVQNRLGEGYGRGNRRVLRGEGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXV9</accession>
    <name>A0ABR3YXV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006803</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01448">
        <property type="entry name" value="TST_Repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01449">
        <property type="entry name" value="TST_Repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="88"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="216"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="342" mass="37770" checksum="D2CFE4A527137D1A" modified="2025-10-08" version="1">MRAPRLVLYRAGAELFSAFSTAPGLRSTTTKRSFSSYLVAPKELHDALKKNPPSSISTDPRVIPLCASWFLPNDAEGRTGIQVFRKQRIPKARFFDLDKVIDRRSPYPHMLPSAKDFAAAMSELGIRKEDTVVVYDSKELGIFSAPRVGWTLKIFGHPKVHILNNFRIWVDEGLPTESGEVYSVECCAYPIPEVDNTKVASYEDVREVALDHNKEGAEGVQIIDARSSGRFTGEAPEPRPGLSSGHMPGSVNIPFDTVLDPASKTFLPADTLKDLFQKKGIDPEKPIISSCGTGVTACVIETALEEAQYGSPAQRRVYDGSWTEWAQRVTPSDSLIRKSVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY67</accession>
    <name>A0ABR3YY67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303039" evidence="2">
        <location>
            <begin position="24"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="640" mass="63562" checksum="89A1B21EED16D45A" modified="2025-10-08" version="1">MKFQWLATGAALALAALPAAASSARRALSLFGNDGNNAVQDTKLRKNNNHVKKDYRLSVPPAETETGVGPVTEEVTVTTTTTVTGEPSSFTSSSSSSSSSSTSSWSWSDFGGPASSSLSASSSTTSADAVSGTSTTPIFGYSTDEIIPPSTSTTPVIWSYQPGPTPNTTAIVAHTATIALSSISASSASSASSVSSVSSDLSSSQSETTVTEFTTITTVTLLTTVSTLTTVSPSSSASSATSSSSYILFSSLPSTFITLSSSALANSSMSPSSSSTSTSTALALSGTLSSTSIDTCYEGTPTASSAPSSSAWSSTYYSPAPSGSSPGIAFSSSSAPRWPNTTRSSTSSSINLSDATLTSSITTSSSSSEVASSGAIQPFFNVTSSASPSIPLSTGVSSSFGNSSVVPSSSSLSSPSVSLSSFVSLSSPPASLTPSASLSVPSSIPSSVPPFIPSSGFLSSLLSSAAPSGSPSVSASVSAPSFSPTPSLNTSIIPTSSVVPSSVIPSLNVSSSFIPPSIVPTLNLSSILPSSVTHLPPLSSVVPPLPSSLLSLSTLLPSLPSSVPSSVPTPSISSLPPPPPPSSSGPAPSSPTASASSTSTTWTHSQFNADGERPATALPTSDAFTPEPLPTKTGGGLFWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ1</accession>
    <name>A0ABR3YYQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006326</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF4">
        <property type="entry name" value="SYMPORT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="110"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="604" mass="67928" checksum="9DC6E7FBF25CFB52" modified="2025-10-08" version="1">MASKSTDPEDFKAAAHIEHRTEQISYNVNARIVNPLAGISKPELQVRVNDFCNENNWPDKRDVFYRGALAAQNPSPDAWGEIEELTEDDKYWLKREITHKWHLPRHLYYAIALCSLGSAIQGWDNTGANGANLSFPQEFGIADQSWLIGVINSAPTLFGLTSAWAADPINNWIGRRGAIFVTGLFCIFPVLGQAFTHNWWELLICRMFMGLGMGIKVSVIPIYTAEVSPASIRGGMVTSFQLWVAFGILVGLSVNLIFYQIGPLAWRFQLGSAFVPAIPVVFFVWWCPESPRWLMKKDRYQDAFVSFCRLRNSEMLAARELFYAHCQYLEEREAFSGTSLRRRIWELVSVPRLRRATVASAWIVISQQFSGISIIAFYSSTIFSAAGYDTRSTLLASFGYGLIVFIFAFPALYTMDTFGRRNLLLLTFPNMAWCLLAAGLAFLMPVDNPARIPVIALFIYIFSALYGPGIGPMPSIYFSESFPLSHREIGGAVTICINNAVGSALGLTFPSLLDKIGPTGAFGFYAGLNILAFIVIFFLIPETKQRTLEELDYIFGVPTRRHAAYQLRHWLPWFMKRYVFFQKNAKLEPLYHLEGVVGASAEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZL0</accession>
    <name>A0ABR3YZL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Histone acetyltransferase type B catalytic subunit</fullName>
            <ecNumber evidence="3 9">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HAT1</name>
        <name evidence="12" type="ORF">Sste5346_006590</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 9"/>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013523">
        <property type="entry name" value="Hist_AcTrfase_HAT1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21184">
        <property type="entry name" value="HAT1_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038084">
        <property type="entry name" value="HAT-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="11">
        <location>
            <begin position="8"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="523" mass="58587" checksum="1A4DE4C023FF6DC0" modified="2025-10-08" version="1">MEHSYDEWVSNANEALEISLVQPGPTGLRSIASFNPKFTYSIFGDEETIIGYQGLKISLRFNASDMRPNLHVSSSKKLKTGEIEPTDIQTVLKGYLADVAFQKPSEFEQAVQQTSKVDYRPPGERIRSFVGSDGRYEIWKGTLSDPAVLQLVKRIEIFVPFFIEGGTFIAKEDATSHTVDSADRWSIFFLYRTRQRPGSADSYEYEFAGYSTVYRFLLPVGPATPPRKGAKQDEFSLPPSDEDGHQTTSFALAKLPCRSRISQFIVLPPFQGKGNAGRLYSAIFDEYLDEPQTKEITVEDPNEAFDDLRDIADLAHLSKLPAFTDVVRIDTAVKIPRTGPSPRNIAGDPAALETLRHTTKIAPRQFNRVVEMYLMQRLAPSVRPTLEEEEEDEGDEEEGKSVAAALAVANGKDKGKSAADSLPPVTPEQEHEYKLWRLLVKQRLYRHNKEILGQLERSQRIDKLEETLVSVELEYARILSMFESRAKLAAEKQMSVKRKLSAADEAAASAAQNGSKRARVEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY3</accession>
    <name>A0ABR3YZY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carbohydrate esterase family 5 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045595482" description="Carbohydrate esterase family 5 protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="32748" checksum="60878916510D2809" modified="2025-10-08" version="1">MRSFTSAAVIGALALAGGASAATGTSTAATAAPSSNTTCAESFYLLVARGSGESITPVGALKYPDYTGLAGDAALQVQSQIPGVVIGGVVYPASDPTTNGAVNLTKYATSEANGTTAVADEIAAYTKKCPGVKIALMGYSQGAQVMQDALCGGLGGDAKVSIGGTTTGFNADPPMSAALVEDNVFAIALIADPSHIANTTYDHGNSTHNGIFARTNTTACDPYVTKGLYGAWCQADDLYCDSGTSSNSELIHDYEPLTYKDDIAQFIIDRWNNYTASVSATPSGSGTASAPSGTATNNAAGRAAGVLSQPVLVGGSVLLTAWLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z001</accession>
    <name>A0ABR3Z001_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006067</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="170"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="447" mass="50423" checksum="FE98ACF14924C744" modified="2025-10-08" version="1">MSDNIDPQTLAVAVQIFLDDLNEFQSNRKGKNRQDDVTDEDIAMDAWQAELQAISQQFMDRALCESIAHAVEQDADLIGVAVQEDIQAAEDRNMALRMSNAKEAAGVSRPSTPALPELDNKLEAKLRELNLSPSTQSAKGSVTVPRVAAESSSSAAERFSQKFRPVQSNPHVVCIACGDRLPLENTHRVPCDHDYCHGCIESLITASIADESLFPPRCCNQPLALLDRNSEPFDFIPEALYSQFYSKKEEFETVNRTYCHIATCSQFLSTKTDIRADIGTCPSCYVSTCTICKGATHNGPCPEDAASQDVLRIAQENGWQQCFGCKRLVELDTGCNHMTCICGAQFCYVCGVKWRECRCPQWNEERLYARAEAVVNRDRNIHVLDRADMIRREQDNLVANHQCAHANWGSRQGRYQCEECRDYLPSFIYECRQCRIMACRRCRFNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z165</accession>
    <name>A0ABR3Z165_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006261</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12398">
        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="299" mass="31217" checksum="E13BCFB6959E5309" modified="2025-10-08" version="1">MSRQPSKIVFVGNIPYGLSEEQISDIFSSAGRVVSFRLVYDRENGKPKGFGFAEYPDPDSAASAVRNLNDYEVMGRKLRVDFSNEGHDEDMPASMGGSNTYNGPGAAANSNNNGPASVPMAVSSSNGGGSSLPPLPPGKDIPPGASATDEISRVLRTLPPTQLLDVLTQMKTLATNEPARATELLAQAPQLAYAVFQALLLMDLVSPEAIQAVVEATPAAPVVPQQQAAPPAQYGGYQPELAPPVAAPPPQAAAPAAAPAQGDLIKQVLELPQAVIDQLPEAERTQLMQLRAQYGGGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2B7</accession>
    <name>A0ABR3Z2B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Respiratory supercomplex factor 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RCF1</name>
        <name evidence="12" type="ORF">Sste5346_005841</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with the respiratory chain complex III/complex IV supercomplex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RCF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="11">
        <location>
            <begin position="9"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="189"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="256" mass="27783" checksum="A2D0F97C27A94E3E" modified="2025-10-08" version="1">MPNALPSDAMPSSFDDNAEYQATPLEKFGRKLMKEPLIPIGCTLTVYAFISATRAIRKGDHHQAQRMFRARVLAQGFTIMAIVGGGIYLADDRKKEREQWALERQQKQQAQTEKWIKELEARDAEEKALRERIARRKELRKAGADDSVVEAELEAQLAAATEREARAKAAAGNSNGGVLAALGGLFGKKEEEASSTAAATSTSSELDPEPEAAQAPAETTTEVKKGARKSHGRSQLDTLGDLFGKRGGGSDGEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y0</accession>
    <name>A0ABR3Z2Y0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="242" mass="26101" checksum="451A9F1A663A421F" modified="2025-10-08" version="1">MPSVAQEAFEADGRNNSGSAHSISILAKKRRWDDSSRASHGSVGSVGNDVVSIYVHGDQHTNHLSSMGTTTFTVNTLSPSQQRKIIPLGSKRLCLSNSSSADDGRPLSISTSPSRAGRESALTHHNHHLISQSLTAPCHICHRRPRRKVDLDSLANCEGCGQRTCFVCLRECLGWTENGTPTEPTHMSSMATTTTPTTPQKQQPPWSTTSHGHRRMVCSRCCVERGEDGDVVCLGCVAVAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3S7</accession>
    <name>A0ABR3Z3S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable transporter MCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005431</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF45">
        <property type="entry name" value="TRANSPORTER MCH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="558"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="587"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="674"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="296"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="706" mass="75400" checksum="72EB8E7855396C3A" modified="2025-10-08" version="1">MSETPPLSSSSSSFSSTRSYSPDLSSSRIYRRRTRNNTASAASRRTARTVAFVSAIVSALCAGSVTVFSLYGHIFQERLHYSQFQVNGVAIAASISCYLPVSLMGYVCDRVGPAPLSLLSSVLFGGGYGLAAILYKKAATEATAGTGGAAPPTTRAYALMVTAFVCIGSATCAMYLSAVATCAKNFGRGRHRGLALAAPIAAFGLSGMWQSQLGSRLLYERLPPLPEDGPNAPPRHGDVNVSAFFLFLAILLSIVGLLGTFTLRVVDEEKLIDEAVDELERSGLLDGSALFMPSTPGVASSSAGIEETAGRSTRIAPGVSRGNSSVSIATSSRARKNGENSNVSRSYGTMARSNPFYPAQSEDEDDETAVDETSRMLRGRNARRSNRVRRNGNDDEDDALASRLLDPGKDDDDDDEDSDESQLEAQQAQFKKTWVLNAETHRFLTDHTMWLFALGFFFMIGPGEAFINNLGTVIKTLYPPSTNFAAGGGTTTAATHVSIVGMTSTVARLLTGSLTDLLAPRPQTQHLQAGTSSSLRSVDVEEESAFRRFLSRFTVSRIAFLLTFALMLSAGLVVLASGAVQNHGDRFWIVSGLVGAGYGAVFSLTPIIITVIWGVENFGTNWGIVAMFPALGATFWGLVYSAVYQAGVSTPESDDPSAVAEDNLCYGTQCYAPTFWAMTGSVWFACVLVLLAWKGRNGWSQRGIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z461</accession>
    <name>A0ABR3Z461_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005522</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="882"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1070"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1112"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1143"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1175"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1212"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1253"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="480"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1333"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="791"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1602"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="803"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1621"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1631"/>
            <end position="1644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1721" mass="186387" checksum="50F8F91749D57DE2" modified="2025-10-08" version="1">MGAGLFFRQVWTLSAKNVRIVLIRNPIATVIRALIIPLILFAFFSFAKYLFVPPAVFGVGTLKPLLSLSDALTDAASTGRHTVAFYNGGLAGGAIDAVIDSVAKQVEDAGSIVVRLANDSQIDTVCHSSLRGVTTCYGAVFFVASPDEGSGGIWQYDIRLDGSLGAGKINVDKSTNDGEVYMLPFQHAIDTAIVGQQTGTGASDNVLANGDVHEYPFTSLTPDERSDEIRTQYQTSLINFLAVAFISGVIGICYHLTGFVATERELGMSTLIDSMMATSEGGRRWGEAQVARLVSYHFSFVALYAPGWILGSAIVSASVFAHSNAAVIILYHVTVGLALASMSLLGSSLFRRSQLSGVSVTIVYLLLAIIAQTLTRPPTGTVAVLSLLFAPCNYVYFVTNIARWEKKQWPINLVKVAPDSPWNIPGIVLWVFLVLQIIIYPIIGAYIERYLYGTITTGRTIENRPADGGVDENGQPLPALQLDHFSKTYTPGPLRRAFGWIKKAPAPVHAVKELTLSAVHGQILVLLGANGSGKSTTLDAIAGTSKLTSGRITLDGTRGLGIAPQKNVMWDQITVEEHLHIFNRLKSPYNCASREEIRDLIKSVDLEHKATARAKTLSGGQQRKLQLGMMLTGGSAVCCVDEVSSGLDPLSRRKIWDILLAERGRRTIIMTTHFLDEADLLSDHIAILSKGTLRADGSSVALKDKLGGGYRIHVHKTKPNEKAAVIIRSDRDLPDVEGVVKKDYFDLVTYIAPSSSLAAQAIRTLEAAGVTDYRFSGPTLEDVFLQLAEEVQQEQEEHERNQAADSGSGSEHGQESSTSVVGEKQQVSDEVQPAASGMLVPNSIDSPNNNGGLKLLSGRKIGYWKQAQVLFRKRFIVFKHNWVPSAAALAIPVLAAGLVTLFVRNQKPVGCSSSEQLSNDDPQNLADAGDILFLVAGPATRFSDINSIVNLFTPMFTNSSTNSSSSGSGSSSNDTSIVSQIFQNITLADTFDDFNELIIQYRKNVTPAGFWLGDSTSPPTVAYLGDYLDQVNSFFGQNLMNVLLANLSISANYADFDIPWSPSTGKSLQMLVYVCLACAAYPGFFSLYPNLERRRHVRGLEYSNGVRALPLWMAYVGFDFAIVLVSSTLMTILFAALSGVWYHVGYLFLIFALYGLASALLAYNISLFSRNQLTAYAFTAAYQAIIFLVYMIAYLATITYAPVNHIDADLLIVHFVASAVAPIGSVIRSLFVVLNLFSVTCDGTVISSNPGKFTLYGGPIFYLIWQSILLFAILLWFDSGNVGASFYRLTRMLRRQKTTAPQPAVDVNGDAFPEDNGPHIGDGGNPDASDRGLCVSHVTKKFKKNTAVDNVSFDVNHSEVFALLGPNGAGKSTTISMIRGDLKPDDGDVFVEGLSVTKKLVAARGSLGVCPQFDAVDQMTVREHLRFYARVRGIEDVEYNVQAVIRAVGLRAFSDRQAHALSGGNKRKLSLGIALMGNPAVVILDEPSSGLDAAAKRIMWRTLAATVPGRSILLTTHSMEEADALAGRAGILAKRMLAAGGTDDLRARFGNRLYVHLVSRGAPRTSDVDTARLRQWVQDTFPGVEIEKETYHGQMRFAIPLGDAGHSDNAKEADLDDDSSSHATPSEKNVATTTTTTSNSLNLASASSSTSAIGRLVVMLDEQREALGIDHYSVSPTTLDQVFLEIVGRHNIQEEGYHREEEAAAAAAAAQKKKWWKFGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z484</accession>
    <name>A0ABR3Z484_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="150" mass="16859" checksum="B130760BE72D36BB" modified="2025-10-08" version="1">MSQWLEDQGCRWNLLGVAGANYELAAAIPAVSKYLLAESGWSRDTVSVHKERLQAILINYLLSKGDAVQIWGEPVADRTKRVPVISFTVKGRSSKDIVDQIQTQSTFGCKWGSFFVDPAVRGLSRPRPGRRRRACQSAHYNTEEEITKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4I8</accession>
    <name>A0ABR3Z4I8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005326</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="627" mass="66876" checksum="5F753A1E94DD7CD0" modified="2025-10-08" version="1">MYRNRNKAKPKEKESLFQCYECPEGVQVFGTEEALITHKWDMIRATKRKSHMSCHVCKLDHRTFEGLVRHYQLNHPVKQQLECPGCQIEFTRLHSLMYHLDNDECPHVRAERVKESRGLQVQATNLFASAAAQAALEGGGGSVRDDGGFNVNAEPVPVAAIQGMTGIPGAPGVPGVPGVVSAAGGECVAVPPDAAISRQTQLGIFNHSGVTVGDFGSFINIHPNVAAAIAAESKLESVRTTTASGIRGNLVDREKNDGNAVPPTSMQASQALLIKRQRQMGVGGVVDPKYVSAANATSAKTKHDVKGKGKAVEDDDLSFGAGTNLLNHHQAARAFRQGDSKAPDLLTDDNLNTINQRFQGLNVWAGQAMLNPEAGMYGVGGGVSGGVRAPSGHATPAPPVGLPGMGARIAKLATNAGIHGLTGQSSPDEVAAAVAAWKASAMAGPGGLGGGEDGEDNYDANTIKIGTADNGIYRMDATPSTRMAITIHHPKHPNFSVGRYYNPISHRYNCPWTSCQKIGKVFKKPGQLIAHLSSETAHSKVRVQCPSCFDLFETVNALMQHCESQSNRCQFRESDDFIPFLNILSAGVAEIHGRNVDMTLQYNVQEGAAPMLLMDEQDSASQAFSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z630</accession>
    <name>A0ABR3Z630_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="4">
        <location>
            <begin position="106"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="409" mass="45705" checksum="267EFE386DE01D8D" modified="2025-10-08" version="1">MAPGALVAEATSPSTTPTPIAKQQTQRRNDQAPRSIFPDGIRTSGQHNPIYDQLKPYAEFPKEIAGPTVWNKEDYEGQPDRWVHRFSEEEIAELSATADAFIASGTPLTGIAKHNFALPLLSQELARVRSDLVDGKGFVLFKGFPADRWSPEKNAVAYMGLGTYLGYFVSQNGRGHVLGHVKDVGDDPSQIHSVRIYRTTARQFFHADDGDLVGLLCVHRALEGGESDIVSVHNVWNTLQKEHPDVAELLTQPIWYFDRKGEVSEGQEPYTKQPVLYLEPGGKGRLYSKWDPYYVRSLTRFSDAGVIPPLSDAQQHAMQVFEDTCQRLALHMVLEVGDIQFVSNCHLLHARTAYKDYPAPAPRRHLLRLWLSTPETEGGWTLPFPDSQELKRGGIQVNDNPPVCPLDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z777</accession>
    <name>A0ABR3Z777_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HypA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="53718" checksum="F43EB09E304710D2" modified="2025-10-08" version="1">MASPTEIHVGTDNTGLWRIQQTSEASDKVSSLLQEDLKTHHVYFNNDGFHNHIPHHLLSLYGTGADATAIQKGYDDNKGYQRKVKPVHEPKEAGDHAEPAAGPLADDWYETAGPQHLGHESFYPDFLRFFQHDIERRDKEEKAAGSGLAGWQALLRDRVFSGTPAAEDLRARLFSGFLHPLIQLMYGIEWGQPAIVAQGLAQAAIHKHQGLDDVLYRMEKEAAAAQKAEPVSIISLFEEVGKSPQLSSAAHWEDPNKMRNGVLARALNEMVAVAAKVSVPATEEGLAARTAEMAEACVYVAASAALHPTKHPKFDFFLIHHVNSIPFFLTINSFEWLSVEAKARLLEWKIRMDLVQYASRACPPLVDISKLESYKSPPSSKASSTAVDEAATTADNISVDATTAAARLFHIEEDGHAIKLIRATGLTEREVRKSLFSNNPCRLLNSDRAWEALYRLEVDAVLAPGNVWVRTAGLEQAWEEIPDISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z778</accession>
    <name>A0ABR3Z778_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_005149</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF19">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286665" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="20"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1895678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="26979" checksum="1C9B8AED3111FE71" modified="2025-10-08" version="1">MLSTSVLGAAALLVGSAAAHGAVTSYVVAGTNFPGYQGFSPGNSPNVIQRQWPDYNPILQASSAKLRCNGGTSAKLSAPVKPGDSVSAIWGQWTHSQGPILVWMYKCAGDFASCDGSGAGWFKIDEAGFHGDGVKVFLNTETPSGWDIAKLVGGNKNWTSTIPPGLAAGNYLIRHELIALHQANTPQFYAECAQIVVGGSGTAVPDASYKAAIPGYCKQTDPNIQVPIDDHSIPQTYTIPGPPVFKGTGAKKAREFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z789</accession>
    <name>A0ABR3Z789_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="2">
        <location>
            <begin position="378"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="592" mass="68506" checksum="2836BE8BD420D9DC" modified="2025-10-08" version="1">MPWSSLPTELRLVVFDRLARITEADRRALKLQLDTTTKPPSMATYTAVCREWHWFFEPYNFRRLVIDDSEVGQFAELVKGPTKRHRLAFIRHLHFHGRLDDYDCSQCTEKSDEDASVREDGRIMLALSTLIAVLSTRNKLEGEEYTCHPDWDEFAKDTEDRSSDPKGSGLTLELSTSSWSDPHHSVRNFRQCRDYPYELPEDIEDRYDAYKAYRERERTHPNNTHGWEGGLWRRHVPDIASATKRVLGAMPMGSVKRLIQPHHMGYISRGEAIPGLMKPNITCRASIIRAIVVRRRFYRNVDHRLLHSLMGLSSESLNDVRLELWEPEYVMCFHRYYWDKKLQNLSIFVDVTIASQYLDFGLTPDMRGQGIAYWTHPHENIALTHLMDATDIFEGAQQELKSHSMNPDWPEAPRITAPFWPNLVNLALTDMNLMHVMIEEREGSEEDEGETPGQYAISLTADMLVHMPKLETLELWCGDKDLGCFFRFETFQGSSTTPPTVTIGSTWDLKGDRIGWWTPKLQSVWTKKAKQYSQLPLSVRNIALPEIRSPSGLYLWAYMEVIDKLALRDLVIDPVSYYDMTQDATHGTDEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7B9</accession>
    <name>A0ABR3Z7B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NRPS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_005235</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003417">
        <property type="entry name" value="PRK04813.1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1684"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="2255"/>
            <end position="2328"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="4001"/>
            <end position="4074"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="4596"/>
            <end position="4671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2335"/>
            <end position="2368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3974"/>
            <end position="3994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="4571"/>
            <end position="4596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="4667"/>
            <end position="4687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2335"/>
            <end position="2352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2353"/>
            <end position="2363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3976"/>
            <end position="3989"/>
        </location>
    </feature>
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        <location>
            <begin position="4585"/>
            <end position="4594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="4674"/>
            <end position="4687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="5141" mass="558466" checksum="AD970FBB13E60D67" modified="2025-10-08" version="1">[encoded data, 5141 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7M2</accession>
    <name>A0ABR3Z7M2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <end position="194"/>
        </location>
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            <end position="722"/>
        </location>
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        <location>
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            <end position="32"/>
        </location>
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        <location>
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        </location>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
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            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="776" mass="85606" checksum="7B18F6CE0349A369" modified="2025-10-08" version="1">MSDAPGRAPRSIRAAPTRGSTRATGSPKSSRIPSCEPCRTSKLACDHGRPVCARCNRKGTPDQCVYRKDPFKRTSNGPNTAARRRSARSPASQLSPNGDYNQLQPLPELANSQPPLQLTLYPNPGFQGSSSLNTILDTVEDGAASYEENEGESQNEVNPEDPNTAHDENANNGVPTTTTGANGQDAIIGSLEDGPSPLQGNMLVMSGTAMIEEGAQVLELLTRFFTQGVLQHLFEEWMGKGLEVHVGSLLVQPFLDSFGSAMDSPQALSRRLFHATKMSTDIDGSASMQDFADKYTGHHLRWETVGLILALAGNAVSKLRAPHSALYRTEAERHAVGRNLLHASNTCASFCESLDILNDVQIIFLYESFLLHSVYFGHQSFRVWGRLNTAINALFGRGIHQRLDRDKDSSGLPFFLVELRKHVFALLYSSDINFSVFLGRPPRISKRHCVIHMPLDVDPETYTMGGDDINVQLSQLNDRGWNTVGQIRTHAVIRWSMITSQIREEALEAIIGPEIPDRDQRSQALTTLRTKIADAWWELPSYLAVPPTEVWRARRPGQQTDTLYLIRLYYLQTLFLIEWTASVHGTSNLDALFVVASDLLAWVNEAIIMRERLNRLGLNTLAWRVSAFGLPAAGALAKCLLAGSSSGTSTATFTKAIRDLSVLIAHMDYLYDSSDGNDKLFSRAKGILIRVLESTLSPKRRRTDAAPTSAPATAQMEDVSPSMPIMTPPLTNGNNGGDTFDQWEFRPELWIGLPGPNSTEVNHLDFMSDFTHFLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z856</accession>
    <name>A0ABR3Z856_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Siderochrome iron transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SIT2</name>
        <name evidence="6" type="ORF">Sste5346_004752</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF107">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="202"/>
            <end position="219"/>
        </location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="626" mass="69729" checksum="375EE89A0A7AB42F" modified="2025-10-08" version="1">MSVFQNIRGRNKAVDSQVIAPSAGEFSAPEVTTTGADVGVLAGDNEKTIAQATQEGYSSGDDSRLSLEERNEIEIKRHGNVVTDRAALGVKKAEAAALVWSRKAVLLTYGWIWVCFFMLALQQSILSNVTYYAYADFQLAPQIGTASILASVIGGVLKLPIAKVLNVWGRAEGFLFFVFVYLLGMIIIASCSGPDGYAAGYVFYWIGYDALYFIMDVFVADTSGLRNRAFAFAFVSTPFICTAFTGPLAAQAYLTHSTWRWAIGSFTIIMFFVFTPLAIIFKFFQRKAEKMGLLVREKSGRTVVQSIVHYTHEFDLIGGFILMAAWVLFLLPFSLQTNGRTTYKSATFIAMVVIGLLLFPVFYVWERYFARTHFVRYELFKKRTVVGACMLAAILYYSFYAWDLYYYYFVEVVYDLDISKTGYMTQIYNVGSCFCGAVFGLYVRWTKHFKYAALCFGLVLMFLGSGLMIRFRGQDSNIGFIVMCQIFIAFGGGTLVISQSMAVMSAADRDGVPMMLALLYLFNSFGGSIGYAVAQAIYANTFPSALESRLPDDLKNQTMTIYNGGSTLQLTYPVGSPARDAINYAWGQSQRINCISSTAMLVLAIPAILLWKNYNVDRRQNKGTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Y0</accession>
    <name>A0ABR3Z8Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SWD3</name>
        <name evidence="9" type="ORF">Sste5346_004657</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="377"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="419"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="464"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="543"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="624" mass="67861" checksum="92884C4CFC4E3897" modified="2025-10-08" version="1">MAPVAVAAADHPAAKRRKVREGDEAVKKQSTDKLSIRGPREKEASKRIRRQSTDSPSAQLAGAIPNIRNVVDDDDDDDDDISSPRRRQRKRREPSSSASSSASRSPRRRPSRRTPSASDSELSSRAHSRSRSHSLSPPRSQSHSRSRSRSHSRSRSRSRSDSRSRARPRARSTSSRFSSRSRSRSGSPVNGTAREDATQRTSARTKRIRRRRRRDATPRPHYRRVLAMRGHDGPIAQVRISPDGRWIASASADGTARIWDAATGAHMTTLVGHVAGLSCLAWSPDSNTLATGSDDKAIRLWDRVTAEPAHAVGETVSDGGAGEGEEGEDGDHTRVAVPSAAAMAVRFARRQLREGINGTNGNGTASSGGARGTRLPLLGHHNYVYCLAFSPKGNILASGSYDEAVFLWDVRAGRLMRSLPAHSDPVSGIDFCCDGTLVVSCSTDGLIRIWDTGTGQCLRTLLLLNEDNPAVTNVCFSPNGRFVLAFNLDSCIRLWDYVAQPSIVKKTYQGHLNKRFSIGGCFGRLADKEDADGSTSKKRHKPFVASASEDGDVVLWDVGSKKEIQRLRGAHKDGVVFWVDVCGATMVSCGQDGWINVYRHTDEEDEAAGGGGNGVAKIEDEEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Z3</accession>
    <name>A0ABR3Z8Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'(2'),5'-bisphosphate nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF2">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="41453" checksum="E7DCA9B477C0AFCC" modified="2025-10-08" version="1">MDSLYKRELEVAIRAVEQAARVSQAVLPDTDKGAVEKEDNLGPVTIGDFAIQALLTATIHDAFPKDTFVGEEDASALRADSVLCERVYSTLQKTVDTTADPSTGAQCVLPTSQADMCDTIDRCQNAPGQGRVWVFDPIDGTKTFLRREMYAINVTLLVDGQQTVAVVGCPLLSPDAETGDDAVTIQNDSIDPTGRGSLLFAIRGHGAHVRPMFEEARQAGVVPAVASTATARRLPRYAASSSQADARPTVLRPVTCYFLQESALDDVHRAVAEQLGVPFPGSDLLGWVPRWSALAMGRANTTVWVYRRRDRHAKIWDHAGAMLLFEEVGGKITDVDGKPLDLLAGRILKNNFGFVAAPADAHAAVLKAVHNVLRSQGRADLLGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q7</accession>
    <name>A0ABR3Z9Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transthyretin/hydroxyisourate hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="175" mass="18564" checksum="113396F064041756" modified="2025-10-08" version="1">MAKDRITCHILDTAQGKPATGVRVRLELVTPSPSSLSSTSTTTNGASASAAPLETPPHSHHHGQATQVFESQTNEDGRVAVWLPYSASNASGDVPVYTLDDVLGKAEAEAAASVAGEETVIPPTTWTLRFDTDGYYGAGKAFFPEVAVTFRVAAGQHYHVPLLLNPFSYTTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9S7</accession>
    <name>A0ABR3Z9S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38700:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38700">
        <property type="entry name" value="YALI0E22418P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="663"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="734"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="824"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="971"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
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        <location>
            <begin position="152"/>
            <end position="163"/>
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        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
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        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
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        <location>
            <begin position="300"/>
            <end position="326"/>
        </location>
    </feature>
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        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
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        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
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        <location>
            <begin position="744"/>
            <end position="753"/>
        </location>
    </feature>
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        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
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        <location>
            <begin position="863"/>
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        </location>
    </feature>
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        <location>
            <begin position="901"/>
            <end position="915"/>
        </location>
    </feature>
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        <location>
            <begin position="991"/>
            <end position="1020"/>
        </location>
    </feature>
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        <location>
            <begin position="1065"/>
            <end position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1075" mass="115287" checksum="9B24A75F718820D6" modified="2025-10-08" version="1">MPAATDPPPPQQPLKPSRYRTIRGKNVPESRRFVGPAANAAAQTVAQTTTALATSASTNSNGTSSSDYSDLSSRRPTPVAPSVPVFHSNDVPRPPLPTLANGHQNGHGNGAGLSSLNSVNGSRNMADAVQHAPPAPPGPKQLQQQQLQQQPSGSTAPSTTPAEGSQHRPPPLRPTRLDTSSPASASASTPVSAPTPASAPILVPLPSARVHEMLLASGTTLDADVVARRDAEAERLLAEQKRKDLERLERELEAASNLPPKSPSRDKFSFLTRRRGLSSAAPPTPTATAFTTSNEPLPASTSPVSPNSGGNGPPSSRPTTSYTSSRVHSGSEPPLPLSAATTLTSASSNTLPPLMDVPSSAPGSGANKHIIVRCRQFSVNVPITPETTVGDALDVATELLPRAINLSGCALVESYTRLGLERRLRRYERIKDIMGSWDTDNDNAFVVMLSEASGAAMKAASGGDTSPKQKKGLFSKSNSDNDVAAITSSNSVGRNGHASDLDLSSVSRSRSTHPPGFIFMSMYHSQKPGRWNKRFITLVEETGQMVASKKADESKLAFLASETSNHSNSNNNNLSDFQNLCHLSDYDIYTPTEAQMRKNLRPPKTYCFAVKSQQRTTVFLNTDNYVHFFSTDDVVQARMFYDRIFAWRSWYLVNKQLALPGRNATKKKKQEEEQQQQQQRQQASVPMPPPSSATLRKNTLQRTLSKSAGNAPPIDSHARFSTAGSLFGGIGDFDPTLDLDRSESQTQQPAATDSRTRSLRTKDEPSTFASGSLLGNDYEERRRADSAATQASGVRDRERLHHHQSSSGSFKGLTAAAGLESSWFPSASEHTTRQRSKSIREVTPSSSRPPSGEDIPLGLQFPQLLQQQQQQQQQQQQKALEREASMSRSRSVRRTLTSSAGPPPQQAPPPMPSNMPAPLIDLTPKFQEAPQWSKEGKGRGVRAPVGTAHLVDLATDRNVRMAAATGVSQKVVGGAVPPPSNANLFRRDQPSSGTSSSSARRSQTMTSSSAAAAAGFSRSRSLAHHGSRTSRTDGHAPPVPLLQRIPGGVPLQDGAASVPMNNLSSRERTTLTRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK1</accession>
    <name>A0ABR3ZAK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046617660" evidence="2">
        <location>
            <begin position="20"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="261"/>
        </location>
    </feature>
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        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
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        <location>
            <begin position="216"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="29247" checksum="708653B0FEDEA5E1" modified="2025-10-08" version="1">MRLLVLLAIAAGRLALVAAIAVPQPQPLPLPPARDSLPPARVPTIADNGLPGLQRAGDTRDTGDIDIALNTLPGRRIGRLGGYTREEFEERAAVAAHVLDSVAAGGRVVRVVVVSTVTSTELQTVTTTGTITPTPTPPPPSTTPSSFSSLSGNTSSSSPSSSRSCDLRYCDAGTSYCEYWGGYSSFDVSQGRPIPGETRTSIGVCSSRASPGPVDSTTTTSSSARGSSSSSSSSSSTSSSQSYSGSYHYSSRSTPGSSSSYNPLDSITCTSTIKSSVSPSSAAVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAS3</accession>
    <name>A0ABR3ZAS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine palmitoyltransferase component</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LCB2</name>
        <name evidence="5" type="ORF">Sste5346_003977</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="4">
        <location>
            <begin position="231"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="656" mass="72115" checksum="419913F9FA0507AA" modified="2025-10-08" version="1">MSPLERVTERRSSQTKGGSRLSQFFSSSPKSRDQTNMSAQQSLLAMQQSPAAGGISASTLSLPKISLSTATAGEAVSDEATTLFEPPSDAETELQRRKDAQFGPLLSRNHLYVSQHPGGPLDPPVVDEPPYYYFLATYISYLLLIGLGHTRDFFGRHFKKTNVNATVRLKNGYAPLNDDFDNFYVRRLKKRLDDCFARPTTGVPGRYITLIDRKSDDYNDSYQFTGTFTETLNVSSYNYLGFAQSEGPCADAAEEAVRKYGVTAGSSRAESGTNDLALEVEREIANFVGKPAAMVFSMGFVTNASSFPALVSKGCLILSDELNHASIRIGARVSGAVIRSFKHNDMEDLEQQLRDAISQGQPRTHRPWKKILVAVEGLYSMEGTMVDLPNVLALKRKYKFFLFVDEAHSIGAVGRNGRGVCDYFKVDPSEVDILMGTFTKSFGANGGYVSGEKHIIEKLKATNAATHFGEAPSPAVLVQILSSLKIIAGELVPGQGEERLQRIAFNSRYLRLGLKRLGFIVYGHDDSPIIPVVLYSPGKMSSFSREMLKRKISVVIVGYPATPLISSRARFCISSSHTKEDMDRLLIACDEVGDILQLKFSTGIAGGLDPLPAGVTPEMEREMIKEQGAQAVIRPPRWKIEDVLAAGEEDAKKRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB50</accession>
    <name>A0ABR3ZB50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="119" mass="13268" checksum="94136BD2AFD6FEE0" modified="2025-10-08" version="1">MSVPTPKGPFRLVTVNTAPERAKRLIGIVVEKLKDSYTIEHVANCERKEDVEATVKEFQPNVLCCASMWTLEESTAIRATAKSLIPDIKTHAIPQGLQVQRGPEAIVEHLVEELPKLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB94</accession>
    <name>A0ABR3ZB94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003740</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Required for assembly of cytochrome c oxidase (complex IV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the COA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041752">
        <property type="entry name" value="Coa3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="11">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="95" mass="10619" checksum="98ACC4633728741A" modified="2025-10-08" version="1">MSGVEHSSYYDRRMRQSPALIRARRPYLVKNTVLGLGISAFALGVYAYTIHVVGQDDFDDVQVPSEPAQSVQQRTQQTQQQPSQIQAQAQAIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBL4</accession>
    <name>A0ABR3ZBL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF31">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="66"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="376" mass="42760" checksum="E060EE5782D631D6" modified="2025-10-08" version="1">MGNLESHKHISPDSGFPITIHPAFNSKIQAHVPPEELRKEVFPDKDRALFADPEKKTLFSVAKRVDLTESIGTVLENVQLSQLNPQQLDELALLVTERGVVFFRGQDLTTEKQVELFEHYGILDRHPAQKDVRHVVIKGSTEDHRNILSYTPWPSGDFHADTSFEINPPSYSMLRMEEHPAVGGDTAWISQYGLYDALSKAMKTFVDGLHAVHTSRLQYDTILDLWGVGPNRPPIDTHHPAVRTHPVTGLKALNVNPGFVTGFAELKKVEGDKLLDFFQYHIHSADDHYVRWKWEVGSVAFWDNRCSVHRVIPGTYKEKRRGIRTTVFGEKPFFDPKSEGRVERQERLDLENGVVTEKRVVVPILEDKEPQVNTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC31</accession>
    <name>A0ABR3ZC31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THO complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="96"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="241"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="39705" checksum="3373607BC262B55C" modified="2025-10-08" version="1">MPSFVIKPRERLQKEKFSNYFSGFKVQAYQDPAAARNMQFHNPPADKGKDTDEVAIQGVRTIAWNPLSSLVATGSSDRTVRVWNPDKPVVRQSTELKGHTATIEKVAFNPIKDAELCSVSADGVVKFWDVRTKTCTNEVRVSGEASTLVWAPDGDFLIVGGKEKGSIGSSKLFILDRTQSTPAAVKTMPVRTNDLAFCWSSKRVFVATGDGRTRILSFPDLEPVLKVNYPVAEGESDEFSLKGHSAECLSVALSPTGRTLATGGTDAIIALWDTTKWTCQRTITTMAGPVRCLSFSWDGNYIIGGSTEGAELEVTQTESGEHIHTFKTAQPVAVVAWAPTRFFLAYAELGTLRIVGVDTERKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCT7</accession>
    <name>A0ABR3ZCT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF7">
        <property type="entry name" value="IMPORTIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="37"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1079" mass="119494" checksum="F1FC388940945548" modified="2025-10-08" version="1">MSFAIEVPGAAVPLNLPDLCKALQAGNSSDHSQRQAASQQLDEWQTHQNYFSSLQSIFLDRSLPYEIRFLAVILLKNGIDKYWRSSARLKGGLHPDEKALIRSRLLHGTVGEENKILALHNALATAKVIRIDYPQDWPTALPDIVALLRNIKDTDPAQLNGALLVLLRVIKELGSARLRRSQTALQHIAEELFYLLGEIYTANTKLWMDYLTTKNGQTGNGADRTNVDYAMVNSLTTLKVLRHLVISGFEHPHKSKLVGGFWSLTQTQFDQFYSYVNSHSQGEGSNDYEIVGKHLLKFTRLHIDMSEAHPASFAALPNSVALARAYWGIVASFAAVYRSSGGLRQNGERGGGEGKSAKLEGPLIERLALRGLLLIKSCIQIVSQPLKTFMYRSAEAQQDQNDGVQRIKTELFTDEFLLQVVDTIITKLFIFRESDLDAWEEDPEDWEAQESESGAAWEWQVRPCAERVFLALIIHNKELLVPPLLAYFQQAMSDKTDLLTKEAVYTAMCNSAVAMDRAFDFNNFLHTTLVRDAQVQGAQVKILRRRVALLLGAWTFYELPEESLKLVYQIYAHLLNTADPANDEVVMLTATRSLKATVDDFQFRAALFEPHAANVFRELINLLQKVENDETKLAVLGTIRSFIERMETVASLFSDTVLTALPAIWTSAPEDTFMIKQAVLSILSTLIMALGAESQKYFTMIFPLIADAMNPASPVHQFLFEEAVELWRSIMSQSGAPLDGNLVDLLPLALPLLDYDSQLVQTCLEIVNAYIILAPEAVLTDRFRVATLTALTGALDTKKWELVHAASTCIQNVIKSGEILGGEAGVASIVGDLVNVGLLPRILQRLHAAWEAHQSTGPNAKQSPIKPTTQVEYIMILSRIALGNPNAILDLLGSLQLQSGGVLQLTEATSGANVEAIWPWLMPEWFGTLDNMGNAENQKVACLGLTRLLEVQRPVGNGSGSQFSDLVLGRLQDYLSMWTTTVVDAQGDATKPDCYVWAEGAPPPTEYDTPLMTAESALAAKDPLHTQTTHAFVMARLMDVIGRVGGEAAFNDNWLVNVDRDVLAGFQGLTTPRLEEGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD54</accession>
    <name>A0ABR3ZD54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487:SF1">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="708"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="846"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="865"/>
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            <begin position="880"/>
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        </location>
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        <location>
            <begin position="891"/>
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            <begin position="905"/>
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            <begin position="1026"/>
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        </location>
    </feature>
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        <location>
            <begin position="1080"/>
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            <begin position="1098"/>
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        <location>
            <begin position="1110"/>
            <end position="1127"/>
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        <location>
            <begin position="1158"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1184"/>
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        <location>
            <begin position="1225"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1267"/>
            <end position="1277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1286" mass="142673" checksum="19240B55586E91DC" modified="2025-10-08" version="1">MPETDYYESSYRRDRERDTVYSSDDDERYKKKTVHRYKVGGSGDRVERVERTTTVDRYEDKDYKPVRRSSNNLLDVVDRRDYVPERPRSAFEVTETTRRTERDRDYYGGGGSRVVYEKTKEIDRVDRGDRRNDRDRETRLARRADDQIVVESFSEDRRDDGHGGNIERWHRETEYYEPAPAPAAPQPIVIRNETPAPGVVVIREKERDRERDHRDRSDKKDTRHEDEYFYERRERREVGPYRGDEEVAVERYERREGGYGDERERDRRRHRHHHHDRDRRDYASDGEFSDDDYYVKKTTVIRRERSPSVDKHHRLHLAEGALAGAGLGALLGSRRNNQTGELPEHRGRKVVAGAALGALGTEVFKRAHSAYNERFGDNDDDDRARSRSRGGGNRSRSTSRHHSKLKTGLGLAAAALAVAGAAKYIQSNRIDKEERNRGRSLHRYSSDEGDYGHVNNRSASRSGTKSRSHSVAKVAAGTAAVAGLVHHFRSKSRQREGKARSHSRLRTGAEIAGAAIAGAAAKKLYDKHKDKKELEREQKEAAYYSDEPYYSDDDRHSRHSRGRGSRSHSRNRSASHSPPPLSGATRTPYPPSGADPELGLVEYGDQPLYADPGAAAGGGAIINQSRDRGHGHRGSYDSAADASEREDRRSRRHHRRDRDNHDGNDSDDEADADVDSDRKSKRNRSASRLRNLAAAGAGAVAGAIGIKKYGDSKKKKEEEEAEEKRERERERRDRHRDRDRDHDHDYDRDHDRRHSHDRDYDRDEDINRRHRHRHHRDEAAYDGGYYDDYDGRPPSPPHASGGAFYPPAPAGAPPAAAGVAGGIMQHPNTNLHEIYPPYNPIDYSGYPPPPGPPPNRGSGAADAQGGAPIPHGPSSGPSSGPVPGPAPYPASYPSTPAAGPVDPVEIPPECPILPPPGPSAGTMPPTGGPSGAPPPPVGNVYEAPGANPNVPPNANTSASRGRSDDSPIINSRPPAAHDGDHVSFTVPLNTVNDIQDLPEDAHEAAKAVGFAPLSPQSSRTLRRHHAEIGEHPTDKSSSTDKDKDKVKGKSRQLPSPSPSPTAAVHSRRQQAEDDDAIEELPDRFDSHGRPLDGRSIGGSANSRTRGMTSRHGDFEFRNPDGRPDGWHVRGQWGVASSDPNGGGGVDKIADSVRSILDGVGGASSGGGGGHPGILGIIGGVLEGLSHHDEGDARRDLGDGDDRRDDRQSGDDDGKKRKRRNTYAGKDGRGRNRDSGRDRDRHREGDRDDRGHDDRATSVDYLDGGYVFDRDGYDGNDARKRRRSWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDH9</accession>
    <name>A0ABR3ZDH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF2">
        <property type="entry name" value="ANCHORED DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932985" description="Intradiol ring-cleavage dioxygenases domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="2">
        <location>
            <begin position="144"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="380" mass="41430" checksum="4D1CDAF6819FD6DB" modified="2025-10-08" version="1">MVGLSALAAVAGLLLSVTNVFAHPGEHPFSPEKRQETLKKQAFSHMVGHNNKRALDAACGGRAEDVAARQQRAMERRFAKFQELRKKRNVDHLTTIDRRSNADFARYSTVQHNFTGIRHLDSNTPYETVFGANTSCVLAPDNVEGPYFVWGEDLRSDITDGQPGVPLHLELQLIDVETCLPAQAVLLDVWACNATGSYSGVSAYGQGGLNSTFLRGVQMSDAEGVVDFDTIFPGHYMGRATHQHIVAHIGAELAEKNKSYTGGTVAHISQLFFDQALIHQVEQTSPYNANPVQLTTNAEDMFTGFAASPAFDPFVEYVFLGEGGDLAYGLFAWAELGINTSLNYDSYAAPASFRYESGSVDNANFFEEQIAGAFPPPTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDM8</accession>
    <name>A0ABR3ZDM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TOK1</name>
        <name evidence="12" type="ORF">Sste5346_003177</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF342">
        <property type="entry name" value="OUTWARD-RECTIFIER POTASSIUM CHANNEL TOK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="66"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="351"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="633"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="644"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="660" mass="73411" checksum="226BE369966D2F2A" modified="2025-10-08" version="1">MHVHEPPISPGEIYSQGFWHAVLASILYFAGSLMLVVNMFGHVCGHYPQRFDLDDDQRTLILQTMLFFFWLAAGAGIYTRLEGWSYSNALYFADVSVLTVGFGDIYPTTNAGRGFLIVFELIGITSLGLVISSISRFVRDISANKIIKSHELHSHKSTLGRTVTNEKELRDRLGLPPTSMPTPGAPVFTTKPAAADNNTSVLGSAAKDSSTAANTSISFGPDSRPGFTRASTAVTVPHGSLPHQDPENRYGHIEIVGNTVTYHEHTATVIVGGRGGAARRVAINRNDLDDMDGSTPRWPWRRRQRRRQQQKKLLLLREEKDRFNAMRDIQEETHRFKQYYALAMAVLAFGLLWFMGALVFMFSEERLQGLSYFEALYFGFVALLTIGYGDLSPKSNAGKAFFIVWSLIAVPTMTILIQELGATVVGTVNRGTFKLADWTVMPKKGLARTFVASLRMWFWAVVEGHKKRLTQYGDRKRQHPAQTAATAAEAEAAEKMAAAAREKRDLELYDEANVHQLARQLAAAIRDVAHDLGADPPKRYDFEEWAHFAELIRFSRRRGGEEADEEKSNEDEGLIEWDWIGEDSPMLADTTEAQWVLDRLCESLNRYTRQQARRQAISGKKGPAVEALKGCVKDNSSTAPGCLSASSSVSSSSAKEYPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFF0</accession>
    <name>A0ABR3ZFF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal specific transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31955" checksum="F6B9E1C42469ADC5" modified="2025-10-08" version="1">MPGLQNSRWALRDGRSSSVPAPCRRPHAENPYVEGPHGSSRGTVARLERTPRDAKSAADELARYSKIVRRMKWKLPFLEMAHQQATATSVEYGTLSAEAELMFKLDFFEYYMLCERALVHLQGVFGITISRGTVAGAKNQAVDRSAKTATHRFHANVLEALDTLENPLHEFLGTGNVRRQLARAKDLRNRWKNADDGDTGATGSRLKQTSPAPLVTYDLATILSSIHGGLDCAFIFTRDFVASTASETETTGSASTTNPPAGTSAMDTDPSMREEEEWGFMVEAMDWEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFJ2</accession>
    <name>A0ABR3ZFJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPR1/FUN34/YaaH-class plasma membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002812</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30226" checksum="98A1D81FE61A43D9" modified="2025-10-08" version="1">MAEYENVRANGNGASSDAEKGQMEALREIATNRSVVMSAEQFEKLYLSPHNKVKGELRQTYGNPTPMALIGFLMCLQPLSCTLMGWRGASNFAASIIPAYFFFGGLLMFITGLLEWVLGNSFPSIVFTAFGCFWFTFGGILCPSFGTYGFYAAAGDAASTGLAAKGFNASLGFFLVAFGLFTAILFICSLRTNVVFVIIFLTLIPAFACLGAAFWYQAEDLAGTVDKVTTLFEAAGAILFVTCACGWYILLSIMLAIVDFPIQLPVGDLSTVIKGKSDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFR3</accession>
    <name>A0ABR3ZFR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="622"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="540"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="145"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="518"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="647"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="723" mass="78416" checksum="0D8D07492210B120" modified="2025-10-08" version="1">MSGRNPSPVGGGNLPPSAGSSSTPLQSPALATANVPPPQVTHPGLSRSTSASAVPSPRATESPSVVPALRPTATVQPCSSSAPPAPTLVLAPAPATAHVQSPAPMHIPASTQAQPARQYLQSQPSQQQLSRQSIDSDIVERRWQEPIQQQHQQTPRAQSMPQHVQTPPLQPQQHQQPSPQQQWRSSQSPFPANQTLPPGNSQPHQPPHGPPRPPDPVVVRRAPIVNPPLQVPPPARAELVFVDPRGGIPHPSPGHDYPRENPKIQDDYMRLTFAIEQSVSDAVRCAMRQNWQKCLLGTGFHQGFMLNALLDSVPPDVARGSVKDFGAKVVKNARVEFAAHLDTADIDEIAGLILAKASDRFLDAALEARLRTIDAKPLINALARAERLGYEPDDIVEEPVGGQERVIPQNLPEPQLAVPTQAPPPRKQCKMCNRVFDNEPPYVYHDSTGACTKYDSAPKDAHAPKPAAPRPSVATPSVPATNGAVRNHSIPPETLLPATRPIATPVRQPLSRHVSELQSSQQSASPPGSGQKNPAADPYAHLSEEQLAALNEELLKAEKIYSEKFREAELITNPLEKQTLVNNLRNSFGTRQSIIRKKWGVRLRERRTKAEIEAERVRMGLANDFSPVPGSSQAGPSYNSIKRMRTNDGSQHGSGSRSFESNGLRRKTPTPGYPLLETPRAQPLPRPADNEDDNMSDSSSDNDDIPARLPDSVRQSLSASQRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH92</accession>
    <name>A0ABR3ZH92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Karyogamy protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="657" mass="68106" checksum="3643BA7ABDD643B7" modified="2025-10-08" version="1">MPIPPPSSIPMQPPPAGGAGLSRTRSLRRPQAGPSASAAAAAQAGQTTEVRSSSPSRLPVKPTAGSTTTLIDQKPRPPSATGGLSSARLRRPDAVTTSSSSSSMAPRPATKPPSSSRSHLISSGPGAAAGGAAPRRPPSSSGRPTSSSGRPTSSGGPSSATAPTFSQMSRTRSAAGASTASSTTAAPVRGHTRNKSASIVSSSSSATTATRPATKPPSRPPSATRPPSATTLSSATVLRPPSVQSSSTTSSGAASRPPTRDATSASSTTATATSTAHRRNALAATTTTTRSVEERRAAAAAATAAAHRPAFSTHQQHYSPAKNLAPKPRIAAILAPPASPSKKPANVALSAETGRLQTTLLQLHLLHRDAAAVTAEWHASARQALAGERLSALATDHAELVQMAGQRAESVNAAALQEWGSQYSEDGSFDLTLEEKIQTLDAVLSGVWSLAGQDHHSDQGHGHGHGQASTSRYVQVVRRFERWAQQTADLVAARQGIDTLEDLMDEDESSGDEGHHSSSKGVAAAFLSNEEAPLLDAAWHEECAHLVHRLEGWQRQLERLGRGGSTQESKEGEEGSSAQQQSSLHRMLTGCRSLVNGMLDELHMIQQLERDAAEQELAWIRQMNTTAGVNNGGGSGGIDMQSHVQQPARAGAIWRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHL0</accession>
    <name>A0ABR3ZHL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460:SF1">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="214" mass="23857" checksum="EF7419131B44FA35" modified="2025-10-08" version="1">MDFAPYQSSPPEHERVMSPPATSPRASLERRSFSPKQPTTTNAASPPPLQHPQPQRRWSNGIPSPSYFSYQQGGNNNDLEGGGGGFGGSPDPIYNGGRDGVINEFDTSLGLRLDYEACMAYLLLPPLGSILLLVLERKSDYVRFHAWQASLMFTIMIILHLILHRSSFLSWVLFLADLGLMGWLTLNAYRDADTLDRYEIPYIGPIASRIVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI56</accession>
    <name>A0ABR3ZI56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secondary metabolism biosynthetic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF6">
        <property type="entry name" value="TRANS-ENOYL REDUCTASE APDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="17"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="376" mass="39788" checksum="074D751E7037AAAF" modified="2025-10-08" version="1">MTATSTPSTQTALVCAGSGEYRLATGVQVASPPPPGMLLCAVKAVALNPADWKMVDFSATAEFIGGHEFAGEVVQVGAGVEGFSVGDRVLAPVPGLFGATIDDSNKDSQISRSKAGAFCEYVPVAVDMVVRLPKSMSYEDAAGLSVVTYAAGLALYQTLQLPLPSVEPLPETKTTAAKPTYVLVSGGASASGTIAIQLLKASGLTPIATCSPENRDMLLALGAVETFDYHNASCGMEIRNYTQNTLAHVIDCVTQAESMKLSYEAIGPQGGRYIALDPFPTRIQYTRREIKADWIMGPTLFGEAVKLAGTYGRPARPQDRLFTSRLFGLVERMLAAGTLKPHPVELRTGGLAAVTQGIEDLRMGRVRARKLVYPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIS0</accession>
    <name>A0ABR3ZIS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanine nucleotide-binding protein subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">STE18</name>
        <name evidence="13" type="ORF">Sste5346_002831</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G protein gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.10">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015898">
        <property type="entry name" value="G-protein_gamma-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036284">
        <property type="entry name" value="GGL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041848">
        <property type="entry name" value="Ste18_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00631">
        <property type="entry name" value="G-gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01224">
        <property type="entry name" value="G_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00224">
        <property type="entry name" value="GGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48670">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="G protein gamma" evidence="12">
        <location>
            <begin position="23"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="G protein gamma" evidence="11">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="93" mass="10493" checksum="487200995B794330" modified="2025-10-08" version="1">MAPYTSRDVGDPSQVRRTKQSMADLKLRRLTELNSRLREDLDRERIPVSQASKSIIAYCNSTRDYMVPSVWGVVPKSEDPYAPQQSGGCCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJL7</accession>
    <name>A0ABR3ZJL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="184" mass="20625" checksum="52DE0C75448FED79" modified="2025-10-08" version="1">MSASLQQAVTRAPVMSALSQALRPASLRPSTAATLTSSSLRLASTYRNPNDPNADDNAGGEVHVGGGGRPSLPQQKYKNKKVWPPDFTRLSPQEQLRFEKRYKRRVALASARPRWVKFVKLVQLFSITFVVIYGVLFMEWDYGPQPFVGIREWFWNTLGLLRGGQNSTVRKANEDSKDNVASEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJZ2</accession>
    <name>A0ABR3ZJZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gluconate transport-inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PTH2</name>
        <name evidence="2" type="ORF">Sste5346_002218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF1">
        <property type="entry name" value="CAMP INDEPENDENT REGULATORY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="535" mass="56574" checksum="3A81F885B27E4F53" modified="2025-10-08" version="1">MKMSSTQKHPMETYHGMVRTPADAIKLFEACRLGLLPRVQRRLSEKERQAIRSGSVFVWDEREAGMRRWTDGKSWSASRVSGSFLTYREMEGKRGGGFNTMRRVSGKTPDSSGRGSDEDQDDGEPDGYRYKADGLMKQSFSITTSNGQHLHLISYYARPGPGDPDLPQPIIDPSLRSVVPVKGMYPESSLSDSMPVATVSRVPQQQHHQQPPHYAHHAPPPPGPHGHHPYPPSYGQPGYSWPPSPIATPPYNSHYTTSSAPYPPQQPGHYSHTPPQPPPPGFYHCPPLPHAQHPHQQPYGSAPPPPHAPPYSDRMALPPPQNMGGPSSRTPPMHHAYAGSSGHPLSNSPRSAYHQAPVLPPVSGPSPYQTSPTSGSRLTLPPVSQGPLPALNSSTTTATTTIPAPAAPSAGSSALTPPYQQQPPPSKAYFGAEATYANGARGNSPSGGNKASLSALLHPTPANSEPNSANAGSTNSTSSSPRHQNAAVAPGASAAAGASGAAAAAGGSAGQQFLQPAPSGEDSRALSRLDKKFCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMS2</accession>
    <name>A0ABR3ZMS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="45"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="287"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="51503" checksum="0F9BEF1C78407151" modified="2025-10-08" version="1">MQRPPAQLLSWPSLHLAAADTATRGPAVLILLSILLSITTLLVGVRIYTRCRITHGFGSDDVLILMAFTIATAFSAAGIAGEQTLQWGQHVWGVLPSSFIPGLKLTLAMQVLFDVATNLTKLSMLALFIRITHASGQHAARRMALCLAAIVLASATIFLLVDIFQCRPVSAYWTLSAQRQCINQASHLLAAGTINTVADLVIAIVFPIQYWSAVDQAKAVAKSASDAAKQPDTPWSRGHNRSKNRSESSTLSSSASSASLVRGTRVVIAGPTLKRKRFNFCLPPAVVTSLFVGGMLVVAAGTARTVFTWQTMTSTDGDVTWNSAPALMASALELDIAIIVASVPPLKPFFCRFLPDRYTAAHSRLSRGHMQRQSRSEKRVAEASVSPLSLSSLRSILFRTKDSTDSEIQRPPLDLNKPLPTLQRGQDDTQTVVEVVEPARPGTYYSVYDFQADADGYIRVRKASADTPMPELGMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNJ8</accession>
    <name>A0ABR3ZNJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit K</fullName>
            <shortName evidence="4">eIF3k</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">eIF-3 p25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03010">
        <property type="entry name" value="eIF3k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="44"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="242" mass="26995" checksum="BE5EB54BA13E0C80" modified="2025-10-08" version="1">MSSEDPAERPEQISAIINGLERYNPEAVGSLEAYLTQQCEDRFTDCNANRTLLKLYQLNPDRIKDEVITNILVKSMAEFPSPQFNLAMHLLSPSVASPAAAAASNNTVSSELAEAVSKLRALNALLEGAQFARFWATMDSDDLYADLTTDIDGFEEGVRVRIAQLISHAFREIQVPILEQWLGLSEDAVRQFVTGTCGWKVEGSTVQIPKNAENEAKKTEIREDVNIEMFARVIRRSWEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP10</accession>
    <name>A0ABR3ZP10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001417</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016849">
        <property type="entry name" value="Rtt109"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF2">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE RTT109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51728">
        <property type="entry name" value="RTT109_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="58630" checksum="EBE70B22C3182135" modified="2025-10-08" version="1">MADDLEARLAAVLPAGHNFGVYHISTPPTKTDALFHPPPSQRPDRTYVESHFLGVTITGLSDLKDKDNGDEVLAFALEIFIFTTAYSSTFFVAKADSSGYLHLLNLPKGTPSPIRAVSSVFLTFLVEQRRRAGVPAIISLFARAQSQYLFPGSVDNLGKHVLDDRGLVKWWCRVMDPLLLEDDKSHGYLVVPGLDTYETRAFLPKRPDQQKQWTLGHPLETPTISHYVTADTPHPPPRCLIPQYPDDPKARYLDELDEEAVRSNGKEEKTDKGDKKNVGWNGQWKSVKSLDQFWEMMAFRQECSSGRLTGFLWVVFEADPVAASAAAAKAHEVAEVKKPLKRKKKLRGYIVSRRPRPKTQQRNALAARPVATAYYRWPVAGRGRLLVDESDYKRINELLLQLDFSTLEKSAVSTRRWVQEAGVGSGDWRMTVVGTQAPVAVNNGNGQIQTASNSNGVTDLSNLVKRKRAPSEAAKAADPAKDYSAAAGVNVLSAGLVRKKTKVVESAPEEAANGAPAVNVLSAGLVRRKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPX1</accession>
    <name>A0ABR3ZPX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ESA1</name>
        <name evidence="19" type="ORF">Sste5346_001278</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(2E)-butenoyl-CoA + L-lysyl-[protein] = N(6)-(2E)-butenoyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53908"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:137954"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:53909"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] = N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:15921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:131780"/>
            <dbReference type="ChEBI" id="CHEBI:144968"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:24181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:45949"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF218">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE ESA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="18">
        <location>
            <begin position="245"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="84"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1902302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="531" mass="59727" checksum="4110480A7FC4F707" modified="2025-10-08" version="1">MSPHGVAVGSGEPRERGKATPETLKIGCIAMVLKDGVARRAEILSIRDKKSGRHYYCNFDNFNKRLDEWVPVTRIDFTQDVEWPVPEKDKPSKDAKSKKTTAAANSKKAAISKKTAQKRLGKREQSSTAASEAGTPHPWTEFVESQHKGTPGEGGDSEDKVMTGTDTGATSTPAATGGAPGEDAAAVAAANAEDAANGDPNAAIRAEAAANLAAAEAGDKSFSREEEVEKLRTGGSMTHNPAEISRIRNISKVQFGKFDLYPWYFSPYPEAFSMEDVIYICEFCLSYHGNLKSYTRHRAKCTLQHPPGNEIYRDDDLSFFEIDGRRQRTWCRNLCLLSKMFLDHKTLYYDVDPFLFYVMTQRDEKGMHLTGYFSKEKESADNYNVACIMTLPQFQRRGYGRLLIQFSYELSKIEGKLGSPEKPLSDLGLLGYRQYWTESIINLLHDFNERDDRCSIEAIATALAMTTQDVEHTLQALKMQVYHKGEHKVVIPTRLLEQRETIKKKKRRVIIPNQIQWKPPVFTAASRTWGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPX3</accession>
    <name>A0ABR3ZPX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ICP55</name>
        <name evidence="13" type="ORF">Sste5346_001593</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF4">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="12">
        <location>
            <begin position="93"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="525" mass="57355" checksum="0BD51683C4B02E08" modified="2025-10-08" version="1">MKPRQTRVACLKQVSRLITSSLRPVAQRPQILRQAARPLSSQLRLLRSRPGVSRQSYSPRGYSTVQAADLLFGQPVHETHPHILKAGELTPGITAQEYYDRRCALAATLPPDSAAVLRASDVKYRSGAVFFPFRQESDFFYLTGFNEPDAVAVIRKTGPDLGDCVFSLLVRPKDPRAEQWSGPWSGVDAARDVFNADEAGDIASIGSWLPSLLKGVNVVYTNPEVDVPPPASSTIAATKSIKSLLDEAGVKRVHPLAPIVARQRAIKSMAEIANMRQAGRLSGRALTNAMRRSWAREKDLAAFLDYEFHKDGGDGIAYVPVVAGGERGRLIHYVLNNAALEEGETVLVDAGGEYGTYITDITRTWPVSGRFTAAQRDLYEAVLCVQRSSVSLCRAAGSLSLDQIHRITSDGLRKELTKLGFDFGFSLTGGGSDALSTLFPHHVGHYVGLDVHDTPSVPRHIPLQVGHCVTVEPGVYVPDDARWPEHFRGLAVRIEDSICVGDENPHILTTEAVKEVVDIEALRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ45</accession>
    <name>A0ABR3ZQ45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="191" mass="21584" checksum="6E7B2A773768D3C4" modified="2025-10-08" version="1">MSSPSPASTASQKHHQQKQSPLYKAVMTPVIFVSFLVSLAWVEFRYSMLRSHEHGNSPQNPNKSNKSAQPQNGNNTATNADAACSQHRMPMPAWLHSLVYRRQPYHYVLVKGADGQPADTDRSYTTAKTTKASNKNDGSYYHSMQRKLLKMESDEAFRIRTTVLWVMGFAAAGSAWLTASFVRWIVGYLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ57</accession>
    <name>A0ABR3ZQ57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDC16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cdc16</name>
        <name evidence="3" type="ORF">Sste5346_000739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF263">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BUB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="199"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="57681" checksum="93F4D45DD017F3AA" modified="2025-10-08" version="1">MPSPAKDGTSAVPTLLPPSSLYPPPSSPSGPRTLRKLQSAHNLGAKANSNNLPSMISQQRLLQQQQLHLHHQQQAQQQLQSIQAQQQRSSSPVRRNISNTATIGTLTSGNVSSSNNTSSSINRSPQRGRANSDATSIQQISAAASANASRRPLLGRSPALDALSIDRLVRDGPPDGDVVGALNNLRWKILETGIKSDSDGMSSARIYVWLILLDCPVLETDAYLSLVHRGASPAYSKIRNDTFRTLTTDPLFRRRVSEASLIRLLNAIAWKLHDVREEKSSRHPPMPQLPTSRQSLPSTQQQQNQQAQDSMTAGGKGVLSMLNNAAAAGSTSANTSPAAKNRARALTLTTEGSETSVSAEPGTYVQGMNVLAAPFLYAARSEAEAFVAFHHLLTKECPGYIRGAMDGVHKGLALVDKVLAIVDSKLSLYLLSKNLSAEIYAFPSVLTLCACTPPLPEVLRLWDFLFAYGPHLNILCIVAQLMMIRNQILTSPSPNKLLRSFPALQADSIKRVTLTIIRKLPADVYAEIVNHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQT3</accession>
    <name>A0ABR3ZQT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">txl1</name>
        <name evidence="6" type="ORF">Sste5346_000331</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="PITH" evidence="5">
        <location>
            <begin position="140"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="35395" checksum="0033C8A80EF6685A" modified="2025-10-08" version="1">MSKVTHISSQTQFAGLLKSSKVVIADFFATWCGPCKMIAPVFENIASQLARDNAVTFVKIDTDAQKDIAAKYRITAMPTFLLFRDGNEIERVQGADPRKLESLVNKLVKEAGSAGGASGSGSGGEGSSGSGGADAGGWWTGAAAPRGYTDITDNVEVLRTELLNVDDAAAGNVRVLFGGSRPTGKSEALSASAADWVESDTDEQLMLFIPLQSIAKLHTLQITSNPTDDAARPELIKLYSNSPHNLGFDEAEDTLATQEITIKPTDWNDQGTASIPLKFVKFQNITSLVLFVVSAQDGAEKVRLDRVRLIGEAGEKREMGKLEKIGDEQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQV0</accession>
    <name>A0ABR3ZQV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ndufs2, NADH ubiquinone oxidoreductase 49 kd subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NdufS2</name>
        <name evidence="7" type="ORF">Sste5346_000347</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="6">
        <location>
            <begin position="220"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="490" mass="55238" checksum="7BB076D06607CD22" modified="2025-10-08" version="1">MSSIYRLAGRGAAKRLCLRPITSSPSTPKIQAALARRTPALRAAFSTTNLRRYASPYEGQGTRIVPVGEDFQVPSPEDLLARQLPTEEYTKAPVTDNNVEGRKIRHYTVNFGPQHPAAHGVLRLILEINGEEIIRADPHIGLLHRGTEKLCEYKTYLQALPYFDRLDYVSMMTNEQCFSLAVEKLLNIEIPQRAKFIRTLFGEITRVLNHLMSVLSHAMDVGALTPFLWGFEEREKLMEFYERVSGARMHAAYVRPGGVHQDIPLGLLDDIYQWATQFGDRIDETEEMLTDNRIWINRLQGVGVVSAEEALNLSFSGVMLRGSGIPFDIRKNQPYDAYDQVDFDVPVGINGDCYDRYLCRMEEFRQSLRIIHQCLNKMPAGPVRVEDYKVSPPPRSAMKENMEALIHHFLLYTKGYAVPPGDTYSAIEAPKGEMAVYVVSDGSERPYRVHIRAPGFAHLAGFDHVSRGHLLADAVAVIGTMDLVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR41</accession>
    <name>A0ABR3ZR41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="406" mass="36974" checksum="BB5E3863DC1DE069" modified="2025-10-08" version="1">MSSLSSSSFMEDCSSYPATVTTTATATTTETFTTTYTHCGKAADATTIWDATYTIIEVVCGDSGSWVQPTLPPNFVETVVVCNETPVTITCPVETGKQTGSVSICGNGVTATANAEAHATANANANAGGKGGSSASANANANANANANAGGKGGSSASANANANANANANSGGSGGSSSASANANANANANAGGSGGSSASASANAHAEANANAGGSGGSSSSASASANANANANAGGNGGSSSSSSASANANANANANAGGSGGSSSSSSASANANANANTNAGGNGGSSSSSSGSANANSGGSGGSGGSSSSSSASANANANSNGSGSSGTTVCINGKCSSTWNNGTSTGGGKGSGSNSGSSAHASASASAHGGSTVVTAGSATLKNSMTLAGAFLLLAGPFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR63</accession>
    <name>A0ABR3ZR63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vacuolar import and degradation protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">eaf1</name>
        <name evidence="12" type="ORF">Sste5346_001007</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="11">
        <location>
            <begin position="586"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="883"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="111"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="799"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="983"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1039"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1244"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1294"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1374"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1572"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1640"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="315"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="799"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1040"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1253"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1308"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1640"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1676"/>
            <end position="1702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1702" mass="184420" checksum="A41A536A5E38ED6D" modified="2025-10-08" version="1">MTEVGLADRLELLRLKRAEYSSIVRSRKRKLRELYAVATDGDGALNLNKFDVDAPPSTTGETKFLLDTDILQGRPLSDARIPTRQKPDLEALKQFFASASASYLKETGIDARPALENGAPPTPTTQDHDSSSSSSITHPESHTLPSTNGRKPQESSENATTQRRSPVQGSLPASARPASEESQSKTPLLTPQTTADLTALNGEKPADIPQNGTASSASTAETTAASQRVVNGTNSAETPAAPAVTFAQQDGDAMEVDGADAKNVSSPSNAANDAAKAGDIPSSPDSIAQTATTPAVHDVSVNTSPENENDSFADGDDKTDRRNSREKEEDQTLADGTRDVTVEAQLLQESSAAGESQAEASNSANKSQLSVQTTTPTTAAAIGTPLQAIDVDETIEDATNKDGASQQASSKLTTTDATNTTLTERTAESSASALNRLNGQSSYTNGAASPSVLAALPTPKPSTGDASENLTINDLVLAGNKKDGKRKAPTVLFGKQKKNKPETTIVPSNLAKAENLFAEDYFTPLFMQTFAQNSKWLKNLDQLVHHARKTISSADSQVSIYDNQSCKILKRVYHLQQQDKWSLRQPKRAQEPVRQKSHWDVMLQEMKWMRTDFREERKWKHSAARSLAVACAEWVQATPEKRKALQVLASIPPRRGADSDDFPMIDNAMIDAAHADEANDAAAGMDNDEVDLVDDGDFTETVVPFATTVAPSAIFALQNDAVVFELNPSVASDRLLAELPMYGSPLEVPKGDLTSKDQDPDAAWRRPVVPVSRYIETPIVIKPRSSLLKKSRYAVDDEVEDDDVEEFVEEVSSDVPANADGTDGTSSAPKKPARNTAAPDNAVGLFDPTLKIMRERLHAGHQFRPPSEYPMPSSGFYEYRPPSQWTVADDDQLKKLVREYSYNWSLTASLLSPKSLFSSGAERRTSWECFERWISLEGFPTDASRSPYFKIYQARIDGAQKAIREHNEKAVATAAAATAAAAAAAQTNGTSGSAPPPPPTPVQRRRPTLAMRVERHRNQRHLASFEAMRKLAKKREAIQHKQQQQAAIVATRKSNEPPQQRPPVKTPREYSRLRAERDQRMAERMVEYTQRQAELQRKNQIMARQQQNQGMAVAGPGVPPQVAAQMAAANGMAMAARPNVPGAPHGVPLRNPQASRPRMPIQSPANPMQGMPHMGVNGASPLPMTNLQQAQLQQALAAQRLLAHQQQVQAQGGQPDMNLVLQARRIQDQQRAVQMQQQQQQQVQQQHQVQHQQQHHQQQHQQHQHMQHQMQQQLQHQQQLQQLQMQQLAQQQQQQQQHALNSQNHTPLAQHAQLGQQGQHSPHLTPQQQQQLQQQQLLMLQQHQMQQQAAQQQLQQQQQAQQQAQQQAQQQAQQQQQSQSQSPHPPQQAAVAQQQAAAAAQKAQAQAQLAAAQQQQGQPMVKVPSVPQGSPPVAGIRPMNNQQTFMANGQAMVGQFNAANGAPMGSPVGMAGGPMAANSPSPRPAMPAQTQLPPNIMSQIRELENGFRAKNPNLTADQARSMAVQNYTQIMMMQRANAAMHSAAGGGPQQALAGTSPRQYAQLLRAQQAQQVQQQAAAGGGGGQGQQGHPVTITPQQHAQMQAVLAAQNAQAAAQAQAAQAAQAQQAAQAQAAQQAQAAQSAQQQQQQQAQAQLQAGSPHSVARSPSLAQPARQANGTPVPNGTPVPANAAVPANNVSQPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRC2</accession>
    <name>A0ABR3ZRC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="769"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="790"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="812" mass="89630" checksum="71F8EDBA1A35653A" modified="2025-10-08" version="1">MDDGDRQPGPLRIIKRSSNAPIRPSGSGSAQGSGSDHDQHPRRASVATEESMDSIQEDPGVLQGSLSIPKKRRNLNSRIDEGASRFYTASEAHAAGMARRRRNNTDSIGSGSDRGDGRSRDNEYEAGGRYASVRAQYLRDGQRAGNLDNDMHSSRPSSSHSGRRLYKDEDVMDNFQRMRLSSEDGGASLIDDRRHQQDYYDSPGESIYGQNASGERFFWPSDRPDEFGRRTSVLSATSSRRGPYEHLSALPPHPQSLAYDSRPVSTSDILVTGPDLFAPEPYARPSTAVPFNSPYKSHRPSESFHSRQMGASRGRLDRRLSQIIGKPEAPAEVDPQILVPIVSVTPECRTVEGNVNSFWVAIELFAHITHPLDTGSSRDRRFRQDYRQASASSFATDDDQGLHRFGYISGMDIKILSSYQSEILEVIGKSPSLLTLLPGSKRLMVVHVHLDTTKKKQSTDSQEYRPLSHSSTSEQLLEDLELQLGSTSQEYMQIQLTYSHSGFPKRDVGRDPMDRDGGCVEVRTTIETTVTALVMQQNSSSMWSPSAAPPAGSPLVDIVAKHWGSEAAKEMAKRIATSIEMRMLRRADKTFRSWDAAARHADEQAQKLRPSTPENGTLDGTQDGTLDEVTPRAASHSQQPPTKKSERQDKGKHPERNVSLGQGQQPTIPARLPKKENRQASSNAMHRSASTSASQKRVSLSQVPRLSLSSANIPTDSEPPSPGCLLPLSKNTRLASGGPRQAIPDTAPRNIRRPMGVDTMNLQNMPLGVSEQNLNSENCDDRMTDYGGFRSNSRSSTVSKRSGKWPWPGWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRD4</accession>
    <name>A0ABR3ZRD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="5"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="529" mass="58858" checksum="2C488E3188CFD3F5" modified="2025-10-08" version="1">MPIPNKTFTREEVAASAKKLTAEGGEDEPLLFIIDSVVYDVSDFLDAHPGGEFVLRQVAGKDATSDFYNLHRQEALEKYIDDLAVGTIEGEKPSIVRPQAGDLSLVPYAEPLWLSPVFKSPYYNDSHRRLQRALRIFVDTHVKPEALEKERTGEHIGQSLIDKYAAAGILHMRLGPGKHLHGVKLMKSEENPNGVMDGKDFDYFHDLIVAQEFVRPASRGFQDGNMAGLTIGLTVVLHYSNDAALQKRVMEECLSGKKKICLAITEAFAGSDVARLRTTAVKTPDGKHYIVNGTKKWITNGVFCDYFVVGCQTDKGMSVLLIERGEGVETKAIKTSYSAAAGTTYITFDNVKVPASNLMGKENKGIYVILSNFNHERWGMVCAVNRYSRLVVEECLKWSHQRLVFGKRLIDQPVIRLKLAKMIALVESHQSWLETITYQMCKLPYDEQAKHMGGPIGLLKMSTTRVAHEVADEAVQIWGGRGLTQTGMGRVIENFNRTYKFDAILGGAEEVLGDLGVRQAMKFMPKAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRL6</accession>
    <name>A0ABR3ZRL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Stress response RCI peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF57">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="110"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="19406" checksum="6FEB040B2AD7B59D" modified="2025-10-08" version="1">MCNTDIFLGLLALLFPPLAVWVKRGICSADSIINILLCVLGYIPGLIHAWYIIAKFPEPDYDYEVLNQDAEGNGRVTYVVVHGNHRNSQGRGSGRGASANNRHHVTTDGAAAANNDGVQPAAPKIADNMNYGTASTNQSSGSAAAAGSSSAAPAAGSSSHDNGGEGGSDGPPPSYAQVVAGDNKVQSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRN0</accession>
    <name>A0ABR3ZRN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucanase</fullName>
            <ecNumber evidence="8">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CEL6C</name>
        <name evidence="9" type="ORF">Sste5346_000601</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016162">
        <property type="term" value="F:cellulose 1,4-beta-cellobiosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF2">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044984922" description="Glucanase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="396" mass="41975" checksum="7A2247B5E3DF1E95" modified="2025-10-08" version="1">MKFQYSALLALAASAYAAPPTQSIKEVARQASAGCSSAVTIDASTNPFKKYTLHPNTFYRKEVEAAVAAITDSSLAASAAKVADVGSFLWIDTIANIAKVEPAIADVPCTNILGLVIYDLPGRDCAAKASNGELKVGEIDKYKSQYIDPIVTLLKAHPNTAFALLIEPDSLPNLVTNADLTTCKDSASGYEEGVAYALKSLNLPNVVMYIDAGHGGWLGWDANLKPGAQGLAKVYKAAGSPKQVRGFSTNTAGWNAWDQSPGEFSTASDAKYNKCQNEKIYVDTFAPLLKAAGMPNHAIIDTGRNAVTGLRKEWGDWCNVAGAGFGVRPTADTGDELADAFVWIKPGGESDGTSDSSATRYDSFCGKDDAFKPSPEAGTWNQAYFEALVKNAKPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS05</accession>
    <name>A0ABR3ZS05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase activating factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BUD2_2</name>
        <name evidence="4" type="ORF">Sste5346_000776</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05137">
        <property type="entry name" value="RasGAP_CLA2_BUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="857"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1278"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1338"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1359"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1395"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1407"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1445"/>
            <end position="1454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1463" mass="162246" checksum="2824FF8CCCE3234B" modified="2025-10-08" version="1">MEGRSSFGGDRDRDRDRDRDRDRPRSLPEHPTSPPPQYASSPQLDHRAGPQLSEAFQASQTTKSSSRTPHLPSLPESPLTPARPSETAAFPPPSVSSRANINTSTITTITTASSTTPDDTIAPVSAPTTMQSTIRAVTPEPLDHRRTVTQDLLDAANAYSSSNSSSTVPPPPPRVFGAMSPQGSPRALSHHGGSTSRRQGVVFSDTMASPFDGPISSSSETQATPASAPIGGITASSSAASISSLGGTGFNSSSTSAVSSRDKKTSSRRLIKRSTSRPTSPLVSPPPSVDSLPLPIPTDNANKVLMLMKTLCGRMRGEIEYRNLGEDSWHRGVSYIEEEKGSLMFDAGDHGPFHAAIVADLRGCRVVPTGRPDKDSQCLELANAEATTEIVFRPVVPAEFDLWLAALLCWQQLRLNPGTVASPPPASKPPTSRSASSSTIDSGKRRASVAKVREGAIIKVGKVMLWDKGVATTPRAIVKRPSTRDLKSIQTSWRRVSCILQGNGEFKLMTENDITVLSVVELTQLGRCAIQQLDKSVLDEDYCIAIFPIYAPTSTQLSIFRPIYMAMDSRVSFEVWFVLLRSFTVPDIYALDPAKGNKVYAITDIQAEQEEAIDDDSTPQTPEEQFVELGGNAMVEEPVRLRHRRLFRLEKTLNIRVTEAKIKPRTYADGSPVIPPPKEQKHDKHYSRHHDKSKTNDPDQLIGSYLAEVILDGEVRARTTLKSETKNPFWREDCEFNDLPASTLPYLSVVLKRVEMLSESVAHQLQASLGLPKQGNLFEINYGSVDIPLANLDRGKDHEQWLPIIDDRQQTVGTMLIKVHHEELAVLSAKEYKPVLDMLQKFNAGLTLQIAEVMPGSLRRLSEVFLNIFQVAGTAGDWLMALVEDEIDGIGNQTTMKKMRFSRRLRSNESMESSSDREQLVRDMGRSLQGEANLLFRGNSLLTQALEFHMRRLGKEYLEEVLHEKIFEINEINPDTEVDPSKLQPGEDINRHWAQLMHFTYEVWECIAASASRFPPELRHILKYIRAVAEDRYGDFLRTVAYTSVSGFLFLRFICPAILNPKLFGLLRDHPRPRAQRTFTLMAKGLQALANLSTIGKKETWMEPMNRFLAGQRQTVKDFIDAVCSIPAEKPNTAPVLPASYSTPLSIMGRLSPVAREGFPSLPFLIDHTHYIAALVKMWMDAHPLSAPGHVYDGDLLEFNSICVELQAWSDECFARTELYRQSSDADSSYPMSEDTLAESMEKASLADTVNLSYGNSSAWMESAEVNSSYSVHISGGRNARLAPPGSSGSEVDDNWGRDHEGRQMSSSGKEGKEPYDVGGSIKILRNGKQARKFLSGIISRKPRASSPEHVGAPGPGGRDNEFDKDRDQAREYESKDRGKGRERGREPDRDHRDREHHKVFHHHRDKDKDKDKEKEKDKDKLSKRDKSAKSEKSDKSRSLNLGESWAPSASAAPELPPRQKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSD8</accession>
    <name>A0ABR3ZSD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3752 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3752" evidence="2">
        <location>
            <begin position="199"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="449" mass="48698" checksum="333C081987EDD09C" modified="2025-10-08" version="1">MSSQIGPEMPAHLTKRKRTPDDDGEDNRRVRLASPATTTKTTTIGPIGPSAPPPAVKATLGPSLPPQTSVNEDEIALDDDSDDNSDTGPAPPPIAKPAARPVMGPTMGPTMPPPDTDLRDSRRGGRDRRARSESKSGSDSGSDSEDSDYGPALPGQDDERRHAAAAEQVNKEEEDAPGPSSFDPYSAAPAQRDDWMLAPPTDQTAASRAADPTKIRSRGFATGRAAAAGEGRAAGGSGGAASSAIGSLWTETLQQKSQRLADTVLGRAPDPRQGRSAAAAAAPTVAMSPAEAAANAAREAQIRAYTESTRGKSLYDAHQESLKGGKSTKDKNRDDKKNRDRERERDRDHKRHPDGDRENKDRERRHDRHDRHDRDHPNRHNHRDREDKDEFEGEVRSTKPTEEDDDPSARAFDREKDMRIGVQINNKQRRDLVSRAGDFGGRFSKGSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSG1</accession>
    <name>A0ABR3ZSG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051714">
        <property type="entry name" value="Znf_CCHC_NABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23002">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="187" mass="19435" checksum="B60E6BA1DC710966" modified="2025-10-08" version="1">MDFQGQQGQQSGGRACFSCGATTHQARDCPNRGAAKCYNCGNEGHMSRDCPEGPKDTKTCYRCGQAGHISRDCPSSGGAPGGGQSGAECYKCGEVGHIARNCPKSSYNNSYGGQSGGYGSYGGAAKTCYSCGGVGHMSRDCVNGSKCYNCGETGHFSRDCPKASTSGEKICYKCQQPGHIQADCPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT36</accession>
    <name>A0ABR3ZT36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF65">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="5">
        <location>
            <begin position="9"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="492" mass="54078" checksum="341AF538A3C294DF" modified="2025-10-08" version="1">MAEYNGGSAKADHLCVLVHGLWGQPEHLGSVASTLREKYSEDQLHILVAGSNSGYNTYDGIDTGGERVCREIEDALKAAADKGAKITKLSVIGYSLGGLVARYAVGLLHAKGIMDKLECKNFTAFASPFLGARSPTRGAFSTVFNAIGARTISVSGRQLFGIDSFRDTGRPLLAIMADPESIFMAGLRQFERRTLYANIINDRSAVYYTTAISKTDPFAEVGAEGGEIEDLPLNFVPGYDSTIMDQKEPMAIDRLAAAMKRVRERKASGEAAKAKAEAMAQQGQLPPAKALRRFLAKPWNRERRLQLFEAAPMLAFALLLPLGLTLFLMNSVYQNVQSSKRLKLHEGGLAGIDIKSYRVPLWMKGLRDTVEETYEDINTAQDPEFTSPNDSDSDLESIAQGGSQQQLPLFNSKSGQKGASNGASPADGSLLNLSPEQFTMIDNLDSLGWRKYRVWIRKVRHSHAAIIVRHDSPRFEEGKTVLRHFVNEEFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT44</accession>
    <name>A0ABR3ZT44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase regulator Nrf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrf1</name>
        <name evidence="7" type="ORF">Sste5346_000865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="129" mass="14334" checksum="725380A17636C674" modified="2025-10-08" version="1">MSSQPLLQTAPGKRIALPTRVEPKVFFANERTFLSWMNFTVILGALAIGMLNFGDRPAFISAFLFTGVALVTMLYALFTYHWRAKSIRRRGQAGFDDRFGPTFLAIILVLAIVVNFVLRIVYSSTGGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUC6</accession>
    <name>A0ABR3ZUC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1903268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24691" checksum="E1E0392F2AA84CB2" modified="2025-10-08" version="1">MNWDLATEEPNRAEQFGQFGSLSVNVSRKDVRCRVVAVSGLASNPHWEWTSYSPETRIACNWLSELLPKHAKGATIETFRYNLLPGSVGGFLSEEGLTSAANRLLKMLDRSSGMLRAAPIVFVAHDLGGIVVKKIFFGTPHRALDEGSWEDLVLSIILASPAKLRMIPNLSTRLGRLSHFLEEVSGEFLDVAVDCRFINIYQDVDGESKDQPVRKPSDMTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUT1</accession>
    <name>A0ABR3ZUT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="60806" checksum="100CE382A0C7941E" modified="2025-10-08" version="1">MPKRSITKRGKGGKALSTPKLSAKKAPANKGKAKAKASIAGSVKSDDGKSDRANSVIDIDDEDDDVEELVAKVSPGSNSGPDLDDIPIYSKKDVERILSRILGEEYYGFEDKYDDEDTSHIPPNAEQRRRNGRQMGRDLIIWNRPYMDAKLLLTIYYECARYNVEIPWDAIAHRLHPGSSGSAILQHLGRLRNVVFVNGHMVPPDLPKGSSNSQDPSLYVLRGFVRMPVNVRWSPDEPLFAAKRAITFKEKFEHSPLNLGDVHCLPFDGDTALEYGIIVDENNKILRQNNRKVPKSKVKVGAFPRKKITAKDTSSATAFATTSDNSAGQPATKPSAKSAPKKTSAKRAVPSPDSDDDFDPSAKSSSARPRPSRAAKRVKTYHEVDPEDDDDDEPSEVLEVQEAGTADVSNDNQAGEPSSAPAQEDDEADGEYEVDPVAAASPHSQQSPIPDALGLFSGSVRDAADEVQVPSDDEDANSGDDGDGDDEPTSFVEMLASGAEVDENDTGALDLAEAQQSGQMSIDHMVHPYFGHYGAQVPNDGMTVSSLSFFHPTPPCHIISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZV18</accession>
    <name>A0ABR3ZV18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="73614" checksum="979845D345165D86" modified="2025-10-08" version="1">MPCTPANDLLDLLDVGQDSRSPRSPSTGPEPARRPGPGPGSDPGSGRADTTDSARQVDEVRYLSHFLHRFAAILDPSLFQTATEVASIPELRKGLIALSACDLAIQTNAVERSPSILVSASSASSASSSLSSSSSASSASPLRSPLSSATARPTRPPSSSSSSSSGSSHLAVAIEYYDDALRALAWQCQSRAIQQDLAVQQDGARERHGTQGTHATHVLAAVLVCALYELRAGSHRGIFSHLAGADALVLQNHASIAQSAHGRALLSLWSRTRAYRRAHLLPFRPLDQEVEMAAHTPGAWSYQLSLTYCCDAGDEIHILLSQASSLRNRLVINTCIPPGQDPSRWYADHFGCPLSLPMFLLGDSKGGSGGDSPHKSLNTVNTMPQIGVQALCRLLADERQSLDQWHNRLPASRLPYERLTTATIISAPTPTATGPTTSSTTTATTTTTTTNSTGVSTTTTKTTTTENTTTVNTTAKATPAAYAWAGAEPLLRPLYFQDLASAKQYLCYALAQLLCCEHVVQEALCTHHTDTGMPSEHTSVHPWACLIVRILLGLDTSALTSLWEKNFDIDLVMVLNVLCTCCPFTSFIHYVRDILLPRAGLGLGFSLSLNTNANFELMVQRRAIQMILDELAKDRVPMLIVPMFSMGREALDTHCQDVRQPMKAAVHGRTRHGPYSACMDMPAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZV67</accession>
    <name>A0ABR3ZV67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22749">
        <property type="entry name" value="Otubain_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.60">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.20">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019400">
        <property type="entry name" value="Peptidase_C65_otubain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042468">
        <property type="entry name" value="Peptidase_C65_otubain_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042467">
        <property type="entry name" value="Peptidase_C65_otubain_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931:SF15">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTUBAIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931">
        <property type="entry name" value="UBIQUITIN THIOLESTERASE PROTEIN OTUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10275">
        <property type="entry name" value="Peptidase_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="664"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="669"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="721" mass="76465" checksum="77AED9490AE4929A" modified="2025-10-08" version="1">MAENPLATASGDQAAIDAEIAAQEAAARDYRPDVNGPGINELRSTEEIKDQYASADHIFVQKTVNLPRAYPLYRAVRGDGNCGWRAIGFCYFEALIYNDNVQLISDEKKRLLELNDYIRDVGGYDPYVYEDMVEETDLLFDAILKALPDTEQAIRAVTEAFNDDSAGNAIIYHLRLLTASYLKGNVGVYEGFIVHDGGVIGYCQEWIERPNCEIDHLRVEVLASILLKPSDMVLEIAYLDRSNGSTVSVYKFPDTNIGRAEDTITMRMSLLFRPDHYDILYRPSLPSKAVAESTLLRFLPADAAMAALVPTPDPAANVATVGQPASSDPSNPLAAPYLPSDTLAAEIVAQTYPVPVRYYERIVHPPGTPSIREDTPDLTPGSSSHSPATMPVKEEPITPAYASPVPPHSAPQQTTLRRESGATTDTSSLVTPTAPAPAGAAPAPSSTGRTPNDLEIHHVAPISYGSAAQSAGSFVNYQGADFQILSRLPGMFNRFSAQPASSPFGMSQGSSWGGAPGPSQGFTKGVSPFPVSPAMTSAPPTSGLADVQHAVPPVSAIPASPAAPSVIPGTPMSAISSGLSDSYSEPAFSVAGTPVPLMDAPTPVPSTPMAYGGAGGTGGGDIGANSNNNGGGGAGRAGSNGAIFLPEPKSTPVRFTKWHFNRLPHDATDPNSSHFRNSRVSTAHFDNPDFQPQEYDPSGGGSDAPSRNRRKSSVLREDNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG63</accession>
    <name>A0ABR3YG63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010302</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000128">
        <property type="protein sequence ID" value="KAL1887320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF200">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24684" checksum="8FE4759E3CDDFBD7" modified="2025-10-08" version="1">MALAMYTMDGITLGVTHSYFYTWLIVARSYAVRNALFIYEANRAMQFLAGLTTGGIMWYTRRFKFVVAAGVAVRILGYGLMMRMRNANGGIAEIVIIQLVQGLGSGLVGTGCFVSATVSVPHREVAQMTSLAVCLSTLGSTIGTAIGGGIYTNYFKTELVKELGTSGTTKLIASVFDSITAGLPPLGSPERDGITRAYTTIIGYFTYVAFGSSIPFIVFAWFLPNKRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG65</accession>
    <name>A0ABR3YG65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ergosterol biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_010418</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000144">
        <property type="protein sequence ID" value="KAL1887129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1887129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13463" checksum="1BEAC7F3ADBCED59" modified="2025-10-08" version="1">MTPYVKTSFSAVTHSVVSYVNPIASLRQFSGPSAPPKNALVAHVYGVKNIYTGLIRLYAAYQITNPELYNLTTLTFVGVLALYSTEHLIFRTVGTKEALASYVIATIGFVWMQSYRSWYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH61</accession>
    <name>A0ABR3YH61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010208</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="59122" checksum="4B47F3C422B2DCA5" modified="2025-10-08" version="1">MTIPSTESLEAEQASFDATIRDIETWWQTPRQQHVKRPWTARTVAALRGSQTLPCVSNPAALKLWDMLKEHHKNRTSELTFGATDPVGVSQMAKYMRTVYVSGGLSGFSENSYPGMDHADYPWDTVPKVVDKLFRGQVWHDQRQRQLRMAMTPEERKTAEHWDYLMPIIADGDMGFGSLTVGMKAAKALAELGAAAIHIDDLALGLKKFTTGQGRTVVPTSEYADRVKAIRLQLDVLGAETLIFARCDTDHAEFITSVTDSRDHAYVLGATNPVFLEKHYTLRRAIDEAVEAGTSVAEARAVWMKDAGLASFDEAVSNAATAAGLSDKLADYTARTGYGTSLQQRRAAAKAVLGLDVAFEWELPRSAQGQYLFRQTVQTIVERALVVAPLSDLSWSRMDLPNYYDLKAYHEAVTAALGPERMFAFAWGGEWPFPESAGWTEERRKNASKILSEFGVVWQVQPMYMIQGVNMEIERAAAIWTAGGMGAYYEQIQTPAVTRKPFKVDGYEKMSWCGGILSDAFFAAVAGEEIAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHU6</accession>
    <name>A0ABR3YHU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010162</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="45"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="411" mass="44529" checksum="0D51CED90C9DCCC1" modified="2025-10-08" version="1">MAGLGVPISNATARVRMVDTTGVMLVKSAPFIQPVQKGHETLSLYVAAFLIDHPPSGRKIMFDLGVRKDYWTLPASLQKRLGTVIPGLRIDKDTTEIIQEQGIALSDISSVVWSHYHWDHTGSMELFPSSTELVVGPGFKGSPSLLPGYPANPDSPIDARALAGRTLTEIGFAKTSLEIAGFRAHDFFGDGSFYLLDTPGHCLGHMCGLVRTTGGTESTFVLLGGDICHFPGVTRPSPQLPLPDVIPKGVLRGNGAYFPSPCPCSLFTDHHPALASGGDADRNGLDPKTTPFYAISNDPSSAYTDPAVAQQSADKLIRLDASPSVLVCLAHDETMLHSLPTLNENPDDDLNRWQERDLKSKIHWGWLNDLARDGRPAWHAAVEGFWRDGQLWTEGKTTLLKNGEAASMICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ07</accession>
    <name>A0ABR3YJ07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000098">
        <property type="protein sequence ID" value="KAL1888197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="109" mass="12757" checksum="E96D951C5154CDDE" modified="2025-10-08" version="1">MFGNTAVPPSMLRRYGRDWGANAQGIYYRHHYSPEWVTADHNLWLPSFREMEWDDAGEADRRLRAKSLLRHILDNERWGKSEYAWEADAWTDVFGGMRNDPVLAVSLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJP4</accession>
    <name>A0ABR3YJP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DPH5</name>
        <name evidence="10" type="ORF">Sste5346_009490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="287" mass="32034" checksum="AABEB867F7B71F5B" modified="2025-10-08" version="1">MLYLVGLGLSDETDITVKGLEIVKKATRVYLEAYTSILLVNKEVLESYYGRSIIIADREMVESSSDEILANAQTEDVAFCVVGDPFGATTHTDLVLRARELGIPVANIPNASIMNGIGACGLQLYNFGQTVSMVFFTDNWRPDSFYDRIKENREIGLHTLVLLDIKVKEPNLESLARGRIVYEPPRYMTVGTCAQQMLEIEEKRQEGVYGPDSLAIGAARVGGKEQVFVAGTLKELCDSDDALGPPLHSLVLLGRRTHELENDFVREFAVDKEKWQSIWAAEYQNKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJX1</accession>
    <name>A0ABR3YJX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="26969" checksum="4A15D67BED8FBE4D" modified="2025-10-08" version="1">MSPSTESLTSRSPFTHQRPLQVQFVYYKASGVPGDDQCDSPGALGAAGSNNAQFDSQRADGGDFANSEIPISALLPDRKCPFRTCEYHTKGFVRKHDLVRHIITHYDGRLYCGFCPNGLAKSFGRPFLRVEPLKRHLAAVHGAAKFRKTQNTTEAYLRDRIREHGSVGAGHCSVCVRPFASAAELYGHIEGCVVQLLLLRAREDNGNAAPLDRAAIFQPAILMEEAGWNAGSYILATENAGALSQGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKH1</accession>
    <name>A0ABR3YKH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009673</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="325"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="631" mass="69076" checksum="6A356123FF67A37F" modified="2025-10-08" version="1">MPLAKRGPKAPHSIHNAGSAGRQQTASPPRRRSSRSQQSARSRTSTPPAITTSAASSGLVFLDGGNGLNQNHGGGLGPDLTDLLSSAIGWEPSAVESGYASASLPAPASATTVLSPPTAPEGTGRVDLNVNVHTDNSAVLIRTAQIQQRWRDLSQTLMSRYPNPGTSARDIATRCILLFFEYLYALTPLVHKATLHKALALVDGDSNNNGQLDPNLDTNLGNNNLEPSLQQDMNGMPSIHAMPTMEMHPEEAFALITAVCAEAAFFLPSSVFPEGSAVADIFLEASRNCLNSYLETDLDTPNANSIIIRYFHSNCLHATGRPKYSWHIFGEATRLIQAMGLHDVRLLAWLPPLEAEMRRRAFWIVYMGDKSAAILNGRPITIHRFSFDSNITLPYPTSMEDDDCPEAGTSPASSSPMSCIIGFNANLELWQVASQLLLEIRVQKEKEAKQVPSTPTSTPSSLVEQRNYFHNLYIGFITELDQLPSYLQPSSRTQSNAFMSQCVNLHVSFYCLRVVILQNLRQLACFAGDDNATAELEPTDLRTTEIVRDMLRLLNNAPFWALQVNGEPLVEKLRLLGGSLLAIIHSHEEDDKNDAPLARRARADFSILLNILSRLDSKASDALRTRVSMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLZ1</accession>
    <name>A0ABR3YLZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009252</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="8"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="382" mass="40059" checksum="344A97E54D614AE1" modified="2025-10-08" version="1">MAFPTSMKAIQVVAFGKPYQINTVPVPTIVGPHDLVVKVAVASYCHTDSMVTEGVFGGNKLPLTASHEGSGTVVAVGSSPSGFKVGDRVMCGIFFNSCGHCVACTKGPECQRQYCTGGYEGNTGAFDTDGFFAEYARVDARWTTHLPDQVSLLAAAPLACAGRTIWRGVQQAIQKAELRKGSWIAIVGSGGGLGHMGIQFARSAGLRVIGIDARDEALQVTRSSGADVVLDARAGQEATVAAVQAAVGNNTASSGRGGGAEATLVLSDVPEAAALSCAVTKNHGTVVQVAQPEKIIIPFQEFILRDLRLYGTLVASPDESQAMVDFIAEHGLHVQTETYDGLDKIEELLHHVHGGQLKGKAAIIVDQSQLDQETKASSRSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM35</accession>
    <name>A0ABR3YM35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial ATP synthase epsilon chain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7793" checksum="8ACD6AC811AF99BB" modified="2025-10-08" version="1">MSAWKAAGLSYNRYLAIAGRAVRRSLKEDKRLVAERRGQLDLRFSKWQGGKQGEAKNVADAQTAAAAEAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM89</accession>
    <name>A0ABR3YM89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="128"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="440" mass="48846" checksum="9472BB0390B5D38D" modified="2025-10-08" version="1">MATQQLPVREKEEAPKAIVSDTKPVDDEPLDPAKYIEAHILPRLDKDVVDYYLNEIVKKASTRPVSIEYIRSHPEEFRNLIAVDTGDGSFPRITDYTLTSEKDGAEFPVRVYHPDPEEHGPGPYPVHLNFHGGGFVLGDLHTEAQLCLNMREAGVVVVDVNYRHCPETLWGKCFEDAWAALTWVRASGSLLNILPDSVSIGGISAGGHITIVLHLRAREEGVPLRLVMPTVPPAGGCLFFKYYTDSKHASFHEFNRSPILPWARIKYFSDVALDSVPNDIAGVIEGDSTEVIRQKRKDALYKVWPQEWLVPLDASRAQLTGLAPAYIRTGEMDNLRDEGEAYGYAVVAAGSQVTLKRYPGGVHTFMYLAFNKQKRVYDIDSVVALRQAHGFAALAPAEVEKRVDRVWAAVKAKQAKEKEEREAKKKAAGVAGKEGDNAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI2</accession>
    <name>A0ABR3YMI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_009128</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="40"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="525" mass="57938" checksum="36276021710374A0" modified="2025-10-08" version="1">MTKNRNDRNAAVIGSALAEVLLETDKYWWQVPHLLKLNLLLIVPMLSSSVFGYDASLMNGLQSLEQWKEYFHHPEGALLGTVVAAQSIGSLVALPFVGDFCDRFGRKPVLLAGIVIICISAAIQAASVNLAMLIVTRVLVGIGGMFSSQPSPMLIAELAYPTHRGKYTSAYWTLFYLGSILSSWLTYGTESMSGSWSWRLPSLLQAGYPLVQLVFFWWVPESPRWLVAKDRHREAALILQKYHAGIDDLSANLSPLVAAEMSEITQAIEMQREAHQTSWYALIATPGNRKRTIIALCVGGFAQWNGVSVVSYFLNLVLNSVGITSSKTQTLINGLLQLFNFAAAIGAAFLVDRLGRRTLFLWSSIGMLISYIIWTACSALNVERDNKAAGIVVIVCVFVVFFHYDIAWTPLLLGYPTEIFPYHLRSKGLAVEMICVYGCLVIAAYCNPIGLENIGWKYYTVFVAFLVIISSTVYFYFPETRGYSLEEIAVVFDGPEAAGVTLSAAKDGGLDVNTVDNVENNDTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMJ1</accession>
    <name>A0ABR3YMJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Quinate repressor protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the 2nd section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF27">
        <property type="entry name" value="QUINATE REPRESSOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="5">
        <location>
            <begin position="598"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="4">
        <location>
            <begin position="740"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="SDH C-terminal" evidence="6">
        <location>
            <begin position="885"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="521"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="920"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="553"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="942" mass="102805" checksum="625D8CACC07EBA55" modified="2025-10-08" version="1">MASVLSGVKRSFAAASADWEGQNGRDGQTGQNGRTQPSESETTSIPSTPTTPTPHDRPHFDADASVILTGVRGAGKSTLAVIASTAMRRKIVEADKVFVDTHGQPSGAFQREHGVVAYRKAQSAVLQHILETYRRGAIIVCSWMERDVQARLSQCSGTNPIILILRDTAAIQTHLRVWDDARVQDLVTASGPVFRRCARFEFFNLSETPTTGMNEATGGAPIPETDDHDNRSPAPYLTLKRAERHFLKFLSLILPRGAIPFIESAYPLASIPTEDRQFTYALSIKLSDFVAGDIDVEEVEAGADAIELVVDCVPAAHETPYARPITPQQANNISRIVSHIRRSTVIPIIYHVVLPDPEVAAKHDAQRNAYLSHVLHGLRLAPDYVTVDLRLPDADIARVRQAVWTSRIIGAVDIEGTPTSPSPETRTPPSWHDPVWLAYYRRAVDQGCHVARLTRRAVELSDNFEVSQFIYSTKASPSQIPLIAYNTGPKGRFSACFNSVLTSVVAEPNCPSVTNTKPASVVSLEAMDTSDSRGSTTPTSDSSSRHTQTRQASIPLSDPGSPSSSSTSTSSTSSSLTARQASVALSSAFVYEPMRLYVFGAYVDYSLSPAMHHVALTACGLPHTYRPNSTDSMDYINKLIHDPRFGGASIGLPFKVTAIRLTHTLSTHARAVGAINTIIPVRQLKADGSVPNYSQILTTRNQSGPVLAIYGENTDWIGIRACIRRGLSPANAVRQGSVGLVIGAGGMARAAIYAMLQLGVKQIVVSNRTVSNAEKMVDHFSGMLERNEMELLSHDDDDSVPTKFHVLRTQQEPWPTDFRLPTMIISCIPTHRIGTVPAPNLTLPPAWFGSPTGGVLVELAYKTLQTPLLEQSRKLAHKGWVSLDGLDLLPEQGFAQFELFTGRRAPRRLMREEVFKAHKDESGRSNLPQLQGRLDNIVNQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNA2</accession>
    <name>A0ABR3YNA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lysophospholipase</fullName>
            <ecNumber evidence="7">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PLB1_1</name>
        <name evidence="10" type="ORF">Sste5346_008826</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the lysophospholipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF62">
        <property type="entry name" value="LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLA2c" evidence="9">
        <location>
            <begin position="38"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="590"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="634" mass="66483" checksum="616F8A80AE16952C" modified="2025-10-08" version="1">MVPTALLACAAVAGFKAGGLELLGQTTTANGYAPSSIPCPSILPTVRAASGLSSQEKSWLALRRNNSLPALVNVLERANLTGFDATAYLRGAADNDTMLPKIGIAVSGGGYRALMNGAGALAAFDSRTPNATGPGQLGGLLQAATYLSGLSGGSWLVGSLYQQNFTSVASILSATGGSLSQLWQFNESILDGPATLSTTKYYRQLFDSVETKEDAGFNTSITDYWGRALSYQLFNATDGGGGEGYTFSSVANDTEFASAQAPMPILVAVERSPGQLAILGNSTVFEFNPWEMGSYDPGAAAFAPLRFVGSAFENGTLPSGRQCMGNVDNVGFVVGTSSSLFNQAFLQISKVEGVPDFLINAINATLARLSGGEEDIASWPNPFYHYGTAHNLNANSTVLTLVDGGEDLQNIPLHPLTLSYREVDVIIAVDSSADTASHWPNGTAMVATYQRSATFPSTNSAGFPIVPDQNTFINLGLNTRPTFFGCNADNMTTPGPLVVYLPNSPYSFLSNVSTFDLEYTNEERDQIVQNGYNVATMGNASADPAWSACLGCAVLSRSMNRTQTQPPAICLDCFSRYCWDGTVNATTPAPYEPTPAIAQPSPSSSPSSSSGGRRSSPVVVGCAAAMLCVLLIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNC1</accession>
    <name>A0ABR3YNC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TNT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053024">
        <property type="entry name" value="Fungal_surface_NADase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025331">
        <property type="entry name" value="TNT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42059">
        <property type="entry name" value="TNT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42059:SF1">
        <property type="entry name" value="TNT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14021">
        <property type="entry name" value="TNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNT" evidence="1">
        <location>
            <begin position="86"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="186" mass="19930" checksum="127E99863CAE3DC6" modified="2025-10-08" version="1">MYCSGTARNGTLNSTYVCGDPRLGPVVLPSHPPADSLVEVYQRLGGLCPGQFLATYYDSAAGSWKYPPYDGFQLDTAGQPIAAVMTLPVGQLIDRFGSEYGSYASPAAAPFMQRALPPSNLDTPPGSPVYPYNYHVYRVVVPIEVTAGPIAAWFGQPGQGVQYMLNDTILSLIDGGFLERTNVTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNI7</accession>
    <name>A0ABR3YNI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008916</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="57"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="493" mass="51869" checksum="C157D69E8846A2AE" modified="2025-10-08" version="1">MFEDMTSQITSQLTSQPYNYLVPGLLVLATTPLLLRLKPSSSHSQDNMSASTGPDHTVVVIGAGYAGVPMAHHLAKHTPANVVNLRVILVAPNDEFFWNVASPRGFVPLDPSAPANPKGTPGYGDDKLFYPLAPSFSKYNTGSVKKFEQIVGRASSLDPDRQTIEVSLNAGGVQTISYDTAIIATGSNITDGTPFKIVPNGGAAETKAALAEYRARVRTAKHIVVAGGGMTGVEVVGELATVYGSDASKDKRKEIIFVINESAPLGVYGAKDSVRNVAADRLKSLGVKIITNTKVAVSKPAAGEGSQTVLSLTSKDGKTSSLTTDVFIPAFGASFNTQYLPAKLLDTSEKNKGRVLTRSTLQVEGYDNLFVAGDASNLQFPSLKNANDQITVLAPTMQTYLKNWAASHPAGAKTNGNGNGASAPAAGAAALKEYNGGHTTILAVSTGPAGGTGQVGSFKMFSLMVWMFKARFLGTDKAADYANGKRIMMDSNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNL0</accession>
    <name>A0ABR3YNL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">O-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="26967" checksum="307A70646EDE2DF3" modified="2025-10-08" version="1">MSSTTSTTVEDTIAAAKAAQADLTPLPVLDTLGDTPQHIRDLLATLHAKSLEQENGVTAESFKGIPFDTFMKDKFIALEEDKCHFVYSLLRATGATTIVEAGTSYGVSTIYLALAAAANAASSGKEARVVATEHEPTKATQARAYWDECGPAVSDVIDLRVGDLRETLKTDLADVNFLLLDIWTPMALPTLKVVQPKMRRGAVILTDNTASAAKSYRDLLTYLRDPVNGFVNVVLPYKGGLEMSIYQPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNL4</accession>
    <name>A0ABR3YNL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA methyltransferase FtsJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="1">
        <location>
            <begin position="65"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="245" mass="27799" checksum="BD19E69BB122E85C" modified="2025-10-08" version="1">MALEQTPEAYAVTYSLPISEGGHKVLFTPRDSLNVDQNFLDITMMAVDMGVDSKDIPKNHPDAGNFLPRQLQPNKLFDLALCDGQVLRTHQRAPYRETREAIRLTSTQLALSLEHLRPGGTMVVLLHRVEDWKNFKLLRAFYAFSSVRLFKPQAGHAKRSSFYMVATNVQSQSAGAAQAIENWKKVWKEATFGTEEEWYEACSERDRDVDVDELLEQFGPTLISLGRSVWKVQADALAKAPFIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNQ5</accession>
    <name>A0ABR3YNQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="285" mass="30930" checksum="F4D5549575186A71" modified="2025-10-08" version="1">MATDGTTPIEDAPQLAFTRLTPPAKPADAGPPAIVFLHGAESCHLEFTRVATHLTANYDLFLVDLPAHSRSKHIPFSFDNTINGLVRLITTYVGEKKAHIVGLSLGGFLALAFARRHPDLVRSVWCTGCAPFTGTRLWFMQHPRLLSGIVTVASKLATEKTFWATLGGAEPIPGLREEVQGNQNMATLRPVYEELALITNDSLAAIDGTVRVAIVAGGKLDNVADTTAAGVVLQKQNPASGAFVVRNAIHWWSLQFPELFAQGVRAWIEERAMPEEYEPLTTLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNU6</accession>
    <name>A0ABR3YNU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="117"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="364" mass="40488" checksum="725EABB18282EE82" modified="2025-10-08" version="1">MGVDPGQPIKFRATPKYATLNSDNKGGPKYGHYSELDPVFSSFKDTADAAVASLWGHDDWDAFRAAWKVPTALPADCPQPGTDVIESYQAIPMRDGAEIEIKVMKSTENVNKNNVCVLRMHGGGWSFGWHGSEAVENLHAASHPNVVLVSIDFRLAPEHRYPVPLNDCVDTLKWVKKNASLLDINPDKIVLLGDSSGSNLALALALIARDENIPGIIGMMLDWPNGCHPMFYQKLRDEQGFELESFVQNHDASVINAYILEFCWDAYVPEDDAHPDPYHSPLLADSFKGLRQAFIQIAGYDPIRDEGLAISEKLRRDGVPAETHVYKGLPHCFSILFGDLTQSKQFQARQNAFLDRVIKEANEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG9</accession>
    <name>A0ABR3YPG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="38013" checksum="ABC225768E43A0B5" modified="2025-10-08" version="1">MAEVPLRKLGANGPLVPSLGFGCMGLSSSYGPVGNDEDRFKVLDKAHELGSRLWDTSDVYGDSEDLLGKWFKHTRKRSDIFLCTKFGVNIKDKVYSMRSDPEYVRESCEKSLRRLGVDKIDLYYCHRVDLKTPIEKTMEVLVELKNEGKIGHIGLSEVSASTVRRAHKVHPIAALQLEYSPFSLEIELPDNNLLATCRELGIAVIAYSPLGRGFLTGQLKSPDDFADGDFRKTAPKYSKKNWGKNMELVDLLVSIARDKGCAPGQLALAWVLKQGDDILAIPGTKNIKYLEENMGSLKVNLTDSEAKTIRDQVEKIELHGERYVGFLEHYSFGETPELEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ25</accession>
    <name>A0ABR3YQ25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="52"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="59240" checksum="67E56324706121E1" modified="2025-10-08" version="1">MAQKDQNEIQAVELQEQRDEPAQNNVGPLMRSKEDSMGIWRTVLRHKRVGLIAMTAAFCASLDGYQINLNGNIVANKGFIRQMASPGTTIIAGKYVSAWGGIQSTGQAVGQILLQYVTEGYGRKPALLVIWVILTASIFTESFASRWDHWLVAKLLSGMGVGMLQSTMPLYLSEITPTQLRGFYINAYSFWFVIGQLFASVALNSLNKSDPYNFRTPIYTQWAMIGAIGIVFALLPETPWWLASQGKMDKARKSLEICNGDIEDYNYDEQLEVMRATVAAERQEAEINNELGQWAVFQGRNLLRFFIAGWPKIAQQFVGLSVFNTYAAYFFQKAGSTNTFMVTIILSCVQLISMLATAVTTDKLGRRPLTVYPYAVTVVSVLCLGIVGCFNYSTKQLSSLLIFFACLATFSTTGASAIGYAYATEVPQQRLRARTSAWALAFSNMISIMFSFCTPLMINGTAAWGVKTGFFFAGTGTVATVIAWFILPEVARRTPAEIDEMFNKRVPLRKFKGYVTEVQMRADQIHDKQDAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQQ2</accession>
    <name>A0ABR3YQQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932970" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="80"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="176" mass="18068" checksum="716A46082B02B76E" modified="2025-10-08" version="1">MIASSLFALVLASAATTGLAAPADVPAGYKTVYITSNVNAKFVVQPKAAKAGSAVVVQTLTSKPEQQWYVKDGSGSGTSKIQLAGTTLCLDAGAKSNWKDMANLVINDCADTADGQNWDIKADGRIAVAASSPQECIDLQYMRATANNPVGLYSCAGLNNAGAADKGINWPLVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRH9</accession>
    <name>A0ABR3YRH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="56132" checksum="96CDAC32C30E9305" modified="2025-10-08" version="1">MLRRRHKKSRAGCLECPTSGNNNGDGTDPLLLIDDADGAINVSHAELIVHLMSNQDIQSLAANREDLTSGMILGLRAGIRTPYLLYAMLAFSARHLSFLAANGSDNKSNTGSKSTSQETPEQNNQPPWMPSSASLPSQSSSLSMASSSSPSSISSPSLSTANSPAPPQPSSAQPGTPQSQSKFPLPSSLPPLSFSSTPPYVTQTAAAAARYKRQAVLLQTRAISLFNTAWRASDGVMDRSNCVPMLLFSSVLGHHLFADSLSRRDDTLDKFLEHYVQCAQLQQGVHAIAITTWPFLVVSEFAPILQWSARFTSREGRGNDCAQLLTLVNGAADDRLNAAEKDACRRAIRLLQVGFDVLYLPAPKTSKTPSTSRTSRNGSADADAMDMDAPADLVTSEEEKGDDDDDDEESGEEKAEHTYRHKMILLWALIMPKEFADLMAVKNPESLIILAYYACLLNHGRHLWQVQDAGEYIMGLINDYMDPAWDKWLEEPRRRMATDVVEAPPEPKEVRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRI1</accession>
    <name>A0ABR3YRI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="484" mass="55814" checksum="6B0E78FD3F22CF2D" modified="2025-10-08" version="1">MPSKPRLICADKDDLVWERLDERIDLWLTTVKTSDIYHAAARFILQHRPGEGDLMHTVLKGGYNIAFRLQYKDGTSVIMRIPIKDAVPYPDEKVRYEVATMRYIKANTTIPVPYIYHYGMAADNPLGLGPFIIMEYVDYHQNLSRALMDPTRPPGKRPILDPYVDENRLEHIYDQVADILVQLDLLKFPRIGSLLQDESTGQIDVKGRPLLANMIDVVVHTSMPEEAIMPALDSTYGTGDAWFSALADIHMAQLVFQKRDVVDDADDARDKYVARQLFRRAVAEGRFSDDNSNEFTLYSEDLRPANILLDKDDKIVGVIDWEFAYAAPRSFSTCPPWWLLIEEPEGWPLGGMKGWLEMYEPRLQTFLRSLERVEAQRSPVGGGNPLSQPLSQCMRASWARKSWMRHYAARRSWAFDYIWWKHLDEMLWGPNEDQDHKARISLLTQQQQDILEPFVAGKLEESKTKDITTMDSDRAAMVLKRYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB7</accession>
    <name>A0ABR3YSB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045713565" evidence="2">
        <location>
            <begin position="21"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="371" mass="39138" checksum="B8AA1EEA61970398" modified="2025-10-08" version="1">MRFNWLTVLLALALGQLGGAEPTVDALPKTKSLELSSPKGSPVSAGELAPTSECKDEVDPLPQSLNGMFTGNAAMDFVIEGSGLAHGVCTLVNHYQHSDHPCLAYSTVVASTIAAIISIATNARSGFAGVGTSNRRALLLRGADSGLGSAYSTALLDAVTEQLLSQGFIVGNSEVRTLSRRSGSGSNTTSFSSYSSPTAATDSVTAAFVIHDVVHPNLTITPADFHFTSYADGTETVLVKHRLADHAQNNSNSNNRTTVAGRSTQVSAQPQHDGPGFKYNYRLDVLADEARGQDISGIANMIGSAVGNHWGWEAENAAMDQWIGAIGIDYILLRALGLGVRIISEIDGFGEDYEDIGICGNMGDRIHDELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSH6</accession>
    <name>A0ABR3YSH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribonucleases P/MRP protein subunit pop1</fullName>
            <ecNumber evidence="8">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">POP1</name>
        <name evidence="8" type="ORF">Sste5346_008002</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="35"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="6">
        <location>
            <begin position="537"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="7">
        <location>
            <begin position="772"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="662"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="959" mass="105949" checksum="CF1D6BE00F709BED" modified="2025-10-08" version="1">MAPKMGHGHGHARVSAGTTPPMRKEPADSLDLSGFISALEQEIGDLHSTIKSRRDDRVEKAFQRVPRNMRRRTASHNARRVPRRLRQQSHRDQAADNTPSVASGLAKRKKARTASAWVHENTKKRIKLQEEKKLARGVNGGGDAEGDDNDDEGEGEEEGDSTAGCCPRRPLPIKNLQLPTHRWQSKRAQMDNPGFLWNTTLVRTPANKTYRMSLRAASVKPGMCTCWDTSYKPTIYLQGPVKQLDEALAIVVEPHLLTTSLRSGASCVDVKLPRSFNYQHQQHAANQGFELSGPGNCGAMTLFYNPTTETTTTTHDDTQRSAFLRVHPTLFSHVWTALNNGIARKQLPVIVRDYRLEIGSIDLTGSGALEMLASIIYPYETKTAPMEPQGREFLKLRSIDTTALASSSGAMLAFNIQDPRLDEPKTAHGVQGNSQGQAKGPSRNIHSILQDWPSDNVARYPSGLFDKMARHTAKKLAPQTTLDKRRGKLSTNERLLLETNPECRPIPVIVAAADGASSVPAAADPHASSKSSTASPSWTIIAPRACIDAIWQRLHLQRSQLSGQQPMPAGLEEERHMALERGRPWFPADFPGTPTGWDWELQSRRRQEKTWNEKPTAKRTQWKAVDLGNGNKGELGSGFACDWEFLFGVDTVPAIATTATVAENASEGSEKRRSQKDNDNDKSFHDKNGHTILAEDTVMDVSEPESEVEPVEPVDSAKLLHEDIQFAALQPQSKAMPAIVRSLQHATWNDVRDAVQTARLHKPVEWRTPYQLMTISVELLRGGVHDARARIYRLPTDSYRDKWLALANTKTPKTQSHNRRPPMPQRMPADADIATRKKLMAQSLLETRLPYPRPTGTGDDDTAEQDLHLPIPGRDDLIGFLTSGALRFLTSKGAGIGHVSAQKLVEAILAGDKTDAHPADDSGTPVGGRVPISRDARLCIVRNAGERVGHLARWTPISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSR5</accession>
    <name>A0ABR3YSR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 16">Elongator complex protein 3</fullName>
            <ecNumber evidence="16">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ELP3</name>
        <name evidence="20" type="ORF">Sste5346_007929</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="16">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="14 16 20" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 16 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 16" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="19">
        <location>
            <begin position="102"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="18">
        <location>
            <begin position="416"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1890932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="65176" checksum="DCF6F7C96C43F6A7" modified="2025-10-08" version="1">MSTTTVTETATSTRRGKDNLPPENERFLRCCADIAHALIEDFEESSRNPRRAPRDINLNSLRSKYARKHKVNGVPPLTAIIAAVPEHYKKYILPKLVAKPIRTSSGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFEQARGRVDQLKALGHSVDKVEYIIMGGTFMSLAESYREAFIAQLHNALSGYQTTNVDEAVAAGEMSNTKCVGITIETRPDYCLQPHLSSMLRYGCTRLEIGVQSLYEDVARDTNRGHTVAAVAETFCLAKDAGYKVVSHMMPDLPNVGMERDLDQFREYFENPAFRTDGLKIYPTLVIRGTGLYELWRTGRYQNYTPNGLIDLVARILALVPPWTRIYRVQRDIPMPLVTSGVENGNLRELALARMKDFGTSCRDVRTREVGINEVKHKVRPNQVELVRRDYTANGGWETFLAYEDPKQDILVGLLRLRQCSEKYTFREELIGQPTSLVRELHVYGTAVPVHARDPKKFQHQGFGTLLMEEAERIARDEHGSEKISVISGVGVRSYYAKLGYWLDGPYMSKWLDGRPGPDEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT24</accession>
    <name>A0ABR3YT24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Sste5346_007671</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 18" id="KW-0732">Signal</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045400589" description="CFEM domain-containing protein" evidence="18">
        <location>
            <begin position="21"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="19">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="105"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="253"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1891408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="313" mass="30865" checksum="BA98E1B85064830C" modified="2025-10-08" version="1">MRSQNSLVFALAALAGIAKSQSFPDEASLPGCGQTCLDQVISEASTFGCTADSVGCLCAAPNFQNGVHDCAAAACAADLLASVTNYVIGVCATAVVSAPAATSTPVTSAPVVSSTPPPAVSSTPSTPPVSSTPTPVTSSSIATSAPPTTSSVPPTSTSTPVTSSTPTPVTSSSATSNALVAPTSTAQSTTAAPTTTSATTSTPANTISSAASSTSTASAGLTAGAKAGIGIGAAVGAVAVIAAIVAIIITRKHKRGGNDRSPSRAHLKISDPMPGSGRVYANERGNGFDNSELEMKSRRYEDMVPRHVPRNMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU3</accession>
    <name>A0ABR3YTU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="58594" checksum="3362A3376B8C7FD2" modified="2025-10-08" version="1">MNVDRFAHLPRRIAHAHHATGPVSFLNPTTRYVKVPAKKHFKTPSKVNGTSNSNGVTATDDAPAVPNDDAMTITNEAGVGAESRPASNNTAQTQTQQQQQQQPFTLSPQTTPEQQHVDGAYQIWRSRDNRKGRHAIVLTNDFLRHRDHSHSGDKKTKPDGTLPHSTNSWRGILHILWKMLTSYPVWDVSYDVAIIFTLGSVVWVINSFFVWLPLAAPWTEFAGETTMGGGVTAVVGASIFEVGAILGMLEAVNENRADCFGWALEEALESGKLSLRPNPDDCKHAHVERTRLFSRRRKGRHHHGNRARNNKNGAVPEESVGGMTITEVPSDDANSSSSDLGNTDTTTNGSNDDTRIHPQRRRWTWWPSWTEFKTVYSREMGFWACLIQLFGATVFWISGFTGLPPIQNRLSTAGINGAYWSPQVIGGWGFIISSGLFMLETQRKWYLPAPHLLGWHIGLWNMIGAIGFTLCGALGFGSATSNAVEYASCLSTFIGSWAFLIGSIIQWYESLDKHPIQIKDSLPDHVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU68</accession>
    <name>A0ABR3YU68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="633" mass="69492" checksum="267B7E968E022519" modified="2025-10-08" version="1">MAYMRKRAAVACNYCRHRKRRCDAKTPVCSLCAESGVPCEYPDAPNDVRAVSRPADADLQPLLSRIAKLEAQVQQQAEFMASWNGVGLGAGGGGLAPAAPSTTITTSPRPPFNSDIAHHHIPGMDDAQDAHDVSLIIPVGHWTTTGNLLSLPQIKNLLGYYPPNFFLQLESSRANAVHAHVCESPALPTLDAAETDTLVDAFFAYVYPVFPVLDRDMFVPLYQKVLEQGLRAEPASALCLMLFALGKMALLDRESGSDTDSTNSGTPAATDELRGIDYFAPAYRIATAEWGFCYEADHILPLALVHGALYLQYMNLPLQAWRMVHLTSINLQYSVASSRERRPHDDTATTSTRLYWACFIFESDTLAEFHVPRTGIELVVDKLQFPSLSTSSGRDALQFLAVCSIRRLLNRIHSTLYSTVLSTTATDATAPSPASPSSPASQQTASAPLYLPRVAEARFDSVCTELIRQLKTWYASLPDEIRPDLDIRAPCDLRDGWLRLRYWSAMHIIGRPSVIYVAMTPPSSEAIPAHVLEYCKICLDSSRSIIVVSSHILGQRTPYTWLLIHALLAHTLIVCLAALTPALQPLVPDAAELLGQVAAAVKPWASPDSSAEMIAWFVQVVRQKLRLSAINRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUE3</accession>
    <name>A0ABR3YUE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="27609" checksum="8B08928FF6EFAD5D" modified="2025-10-08" version="1">MALLCVTGLEKGDAALLQQYLGLYHATVASQSLYDENRWPPSMLSMEKEQRRRLYWYMYRLEVHTALVLGHPVRCPELQSLVAYPEVPDFDGDDDDEVEWLTGWNFVTDLYRGLEHLLAKFRPRRLLMHHSRIARSTALPTMFLIDFDPESKILLPLKTALDKLPLVRIMAYAFSKATFSQACRTAIDLVEDMASIPLDYLKWTTLAATQELSGIGHILWQFMRQDLLLADYRELKSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUL5</accession>
    <name>A0ABR3YUL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gemin-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794:SF0">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794">
        <property type="entry name" value="GEMIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="361"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="575" mass="62813" checksum="E3359A573D26C7E3" modified="2025-10-08" version="1">MAATPNPTPAVDATYGQRSVFGGEGLPTAPIDEELDCEDEQEALAYLRLVREQASKIPHVMVMPRYGPQALPPGLVEARAEEVAAARRQVTPQKKKRRRRRHWDEQNDGVAKMSYGDEGEANDTSNGNDNSNAAKKRRVSRQQAVNVGLSYDDEGPANGGLNYEEDGEEDEEEDEEGEASDDDTAGDKDDKDYSLEHHDLYESSVGDARGYYHDGAYVAAPAEEEYGFSSAGYTNGHGQNGGGEEGDANVDANANVDPEAESARFSAAYRSRLLLTHFAELRTIVRPSSENYDPNQLADAVAALPPDHDTDVGPLSTKSGVYRRWLHLLRTTDPLPAQIAAMDKVSVLRLLRVLLRGLLAGGSSSSRSSRAGRFEQKLLGGGGHGNNNGNSGIDMTGRTSRWLWSLFARLPDRGELDYREVGYIRDVAKQAVMRLAHLSYDMAGTDIQGGGHGEEEEVDGNEVPVQEDVGEAEKVELPKVDNETAEVNEDTEDVPMDMEPELETGETKAAEQQPAGEDEKLQEAEAVEDEPVQEDEDGEMQQRATLEMVLAVAGEFYGQRDLLAFRTPWPATSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV06</accession>
    <name>A0ABR3YV06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007253</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="571"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="652"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="711" mass="74058" checksum="9D94CFC232225B99" modified="2025-10-08" version="1">MPGSGVDHSGPLAFRPGRHGGRHHHAHGRHHHGPPPPPPGSAPAPAPPGNELALITDDAATEATATDATTAKDNDNDNEKGTDNNDNNDGNGDDSHEGGRRRGGGRHHHHWGGRHADWEAYAGMPGMPWGGPWPAGVPPPPPGFGGPFGPHGPHGPHGFGGGRHGHRHHHGHHEGGPGGFGDFHAHGHHGHHGRGFGRRGRGGAEDGTANVTDEEQHGRGFGRHGGRHGGRHGHYGGYGRWGWDESDAATAMGTEAAEPMMTADAKFGTEEEVTTTSSSSSESESEEDVTMIEKEDSPSTVRGETAAAGAAAATAAEGEQPTPGNCFGRRGGGRGRWGGRGFRGWGGPRGPPCCESCEEAHSARRAARHARHAARAAAYAARTAGEEGTAPTDPAEPGAPGEGEGDRPRGCRKGRHGGRHGHGHGAHAHGFHGHHGPWTRGDFFDAGFGPGGPYFHHSRFGPAGGPHTHGPHGHHGRHGGRHGAGGPFGFGGPRGPFGPAGPFGPAGPFGPDGPIGRAFGPDGVGRRSFGPMMAALANHPVARNLREMSRAYFGDANTTRDANTTADAAGDDADYFVPPVDIFVDDNRGGWILHVALPGANKENIDVQWDADRGLLTIAGVVVRPGNEAFLEGLINAERRVGLFQREVRLPPFGDQSQQTERPASDSSASSAAKQEVDAAGITARMENGVLIVVVPTVDKEWTEVQKVDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVR8</accession>
    <name>A0ABR3YVR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cystinosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007234</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="305"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36641" checksum="58A5274DB4EEBAB1" modified="2025-10-08" version="1">MDFLAAISALFGWVYTIAWSLSFYPQPLLNAKRRTTSGTTVDFPLINCLGFLSYLLSTGAMRYSATVRAEYAARHHGLTPTVATNDVVFAAHALILSLFGVSQYLLPQLWGWNADREENDGTREGLLAGDSAVVGYDGRQQHQQQQVRRRRVLGGNTKPSNFILGIMAGCITGVGFVVLLVFRDNAAGTAVDAMLATTTTSSRWQWLDVVYALGYVKVVVTLVKYSPQVLVNWRNRSTQGWSIYSMLLDFIGGVLSIAQLLIDSYRQHDWSGLTGNPVKLLLGNVSMAYDLVFFAQHYILYPEDSRGEGKDRAYNEDAEEGSSRARDGVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW49</accession>
    <name>A0ABR3YW49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="36320" checksum="56C1412BDD32080C" modified="2025-10-08" version="1">MGKKKVMVGYGVDIDAVAGWLGSYGGEDSTSDISRGLWAGHTGTRRVLKLFEKYDIKASWFIPGHSLETFPEECAMVRDAGHEIGLHGYSHENPVDMTLEQQRDVLDKTFRMLTEFCGKPPRGSVAPWWETSAEGTELMLRYGIEYDHSMSHEDCQMYWLRTGDSWTKIDYTKKAEEWMKPLVRGRETGLVEIPGSWYIDDLPPMMFMKNSANSHGWVNPRDIEDIWRDHFNYFYREYDEFIFPMTIHPDVSGRPHVLLMHERLIEYINKHEGVEWMTFAEMSDYFKSKNPPPEGALMPASPEEVMKNLANGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWE0</accession>
    <name>A0ABR3YWE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial aspartate-glutamate transporter agc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AGC1</name>
        <name evidence="14" type="ORF">Sste5346_007233</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="172"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="347"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="445"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="543"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="707" mass="79082" checksum="163EC51E86A60711" modified="2025-10-08" version="1">MSPTSTVKEAVKESLLGHEEPAQLSAQTRHRFLKNAVPDAETGELGMGLNEFINAIAPEGEDYHKIKREQYTILFPVADRRGQGRVNLSDWAYFENILMKPDAEYEIAFRLFDVERLGTVRYDDFRRLYELNKGTTTIPFNWDCEWAKLYIGDKRKRHDMDYEQFSQMLRGLQGERIRQAFQLLDKDGDGYIEPDEFERIILETAKHKLSDHLLEHLHTLCNISKGTKISYANVRAFQNMIKEMDLVELIVRRACAKSSDNKITRTDFLNQAARITRFSLFTPMEADILFHFASIDEPSGRLGLADFAKVLDPAWRSQERVEGVSDRVQQTAERAKSSMGSFASKAFESAYNFGLGSLAGAFGAFMVYPIDLVKTRLQNQRGAEPGQRLYKNSIDCFQKVIRNEGFLGLYSGVLPQLVGVAPEKAIKLTVNDLVRRLLTKKDGSIWVGHEVIAGGTAGACQVVFTNPLEIVKIRLQVQGEVAKNVQGAPKRSAMWIVRNLGLVGLYKGASACLLRDVPFSAIYFPTYSHLKKDMFGESKTKKLGVLQLLTAGAIAGMPAAYLTTPCDVIKTRLQVEARKGDTQYTGLRHAAQTIMKEEGFRAFFKGGPARIMRSSPQFGFTLAAYEVLQSVLPFPGSAKSEKVQTGVADAMSSFKDKLAHEVQTPFVRSRNALKIILDLDEDFGKLKLPDHKGWQSLPTTMGGGGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWG2</accession>
    <name>A0ABR3YWG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007072</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009725">
        <property type="entry name" value="PRK13252.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="505" mass="53754" checksum="CEF9398857DA8C17" modified="2025-10-08" version="1">MSQPQEPDRHTFYNGKPQPSSSSSSSSFTSIYPGTNKPVARIHTSSPATIDAAVASAQAAFPGWSTTPPIERSRILLRAVALLRSRNDDLARVETLDSGKPYSETSTVDVVTGADVLEYYAGLIASGGLNGEHFTLRPGAGGAVVQTSKEPLGVCAAIGAWNYPLQIALWKSAPCLAAGNTLVYKPSEFTPLHAQSLAEIYKEAGVPDGVFNVVYGAGEVGAALTAHPTIAKVSFTGQVSTGRRVAGAAAGHLKYVTMELGGKSPLVVLPDADMSQAVDGAMMANFYSSGQVCTNGTRVFVPAARKAEFETTLLQRMQHVRAGDLFDMATNFGPLSSQTHREKVLAYIRHGIEKDKAKLLCGGLGRPENIPQDLKDGFWVQPTVFTNCTDDMKIVREEIFGPVLCILPYDTVDEAVTRANTTELGLAAGVFGRDLNQCKEVVAALQAGITWVNTWGESPAEMAVGGWKQSGLGVENGRRGLEAWLRNKSTLIEMSGSVATVFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX39</accession>
    <name>A0ABR3YX39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1742-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013640">
        <property type="entry name" value="Vfa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218:SF1">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08432">
        <property type="entry name" value="Vfa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="23266" checksum="EFE0A251C08F2638" modified="2025-10-08" version="1">MNFFANVYTHRKVAEGSAKGCEICFKPTTSVLITPENKDFFYICPNHLKDRGFATPIVDKAAEEAKKKKAAEEKEAKIKEEMERVKKEYDERQKKKKDKKDKKDDDKDKDKDENDKDKDKDKKDKKNDEKEKDKDSKDEEDKDEKDKTPENDEPRVFALNKHIYLQRIEKKKQAEIAKRNRERLANPGFFPSVPKGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXT1</accession>
    <name>A0ABR3YXT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006628</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="344"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="774" mass="85840" checksum="B1ADF9724F1329BA" modified="2025-10-08" version="1">MAPTIPVATQAGMFHTFQGVTPRKQSTDSQDGTKAVATNTSKRVTTPHACAECKRRKMSILKRLYPGHEVQSLLPLSRPELLALLDPHAGDPGLSALPSPPLNTSPMDDLKSPACLKSEHTLSSLEQIPTRGAEWDEERRDHDPIPAEADDVNALSLAVDRQTSYLGASSIKAALMVMLKVQPNLRNSLASASIHNAVEMSRTIPATKTQSNLQVQKHEASTGASTARKELQHVSWSWKGQTLIDAYFKRIHAFIPMLDETAFRADYLEGQRSDAPWLALLNMVFAMGSVAGTKSEDTNHFTYYNRAMEHLPMDAFGSSHIETVQALAIIGGYYLHYINRPNMANAVLGAAIRMASALGLHRESLAHGGTTDVAAAETRRRTWWSLFCLDTWATTTMGRPSFGRWGPAINIQSPEFGIATGRDTTQHAGSLPLIENIKFCKIATQIQDMLAISPLLRPDDRCSLDAQLVNWYQGLPWLLRTTDPCAEPLYIARCIMKWRYQNLRMLLHRPVLLGLASSGQTHAPESEIAAVEACRELAKQTIEDISHEWSRNQMSGWNAVWFVYQAAMVPLVSIFWQWSSPRVPEWHKQIESVLAMLEAMEEWSLAARRSREVVWRMYEASRQPGLMQPHPAATLMHADAAHNMHPQQQRQQQQQPHQHLVNEQSHGLMLSNAINAASAAAAAESEFHMSPIGFESEVGMLGMLDQEGLWDLDGMYWGQDEDVDFGAAVSMPAGIPAPATAVANPFQPNVHDAMMPMDHGMMNNYAASTFSFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC0</accession>
    <name>A0ABR3YYC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006821</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="675"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="735"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="876"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="770"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="878"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="950" mass="106270" checksum="6C28D774741F8617" modified="2025-10-08" version="1">MRGITSCLECRRRKMKCGRTQPCDHCHKSGRVCIYLGDRLDPDSQGKITEIKEKVSSLELQLQKSVVHQRIGSGLLGSDVPAYSLDPAENGLEISHMVTSDLIYDHADENSMDEDEEEDEATNDMIDLGFKVGRMRMTERIGGLNRPRLAEEINVALASKPGTFGFNLSPVGSQRHTPRATQPKTSARDGFNGDFAHDDNDMSDAPPIPDFLRPSSDYIPPSSSALFGHLTAVPAVQNLLPSSWICDFLKNTYFKSVHPIASCLHQPTFEQQFSEFLVLVDRGRQPRRPRQALVLAVLFSGVVAADENEIAVQFNVRKVDLVGIVKYGVEASLGRANLLRTTSVEAMQAFVIYLVALCRDEVSRSHSIMVGAAIRMAECMALHRDGSAFGLTPLETHVRRLIWHQLCFLDIRTCEAQGPRPTIHREDYDTFLPYNCDDADLTLETEMAVPFTSKQSWASSFLAVLRFEVNEMMRIIWIDRFKLERRKSHLTIVMAKIEKFCHRLNQKYEGYLDDATPIKRYTKLVKELFICRMHVMVLHPYHSNTSNPLSERLHSSLIQSGIRIIEIGIELETNPEYAQWRWYLGAFMQYQIALLLTTEAFHGQSVSESDRISRCLDYVFDTEPSQSLHEKAQGILYEVMQKSATYCEFRKLRAPTSTKQAVPQAQLAQQTLTAANGGMPLPSVPPLRAAPNSSQDKPGIGMIKDEIISPAIPSLPQFSTSGPVPASMITGTVPSMPFQLPNQQYQPLGNGQPYPHHNQQHHHQQPQPQPQSQHQIQQHQQKLQQRYQAAPNGRESIPRAMAPTDTAGLLGSDQAYAFHPPPGQPMAQAAPYTAGSNMVFSGVANGEALWGHPQMVSADSPENFGGGEWSANIAVHGQTQQPQQAQQPLQQQPSPAQHHQQQPQPQQHIDLGRHQYPFATTAGHGQYQEQETNLLDGISWDDLNTMLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYD9</accession>
    <name>A0ABR3YYD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF14">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="58160" checksum="C620456AF53896AF" modified="2025-10-08" version="1">MEGPASRRAAKVGHRKSRNGCTKCKTRRVKCDEVRPICSNCSRLGLECAWPTAEAPAYNHATNAHLPSPSAKSHPASLQTAGSSSSQLSPAQTPTPTMSNALPFPHPHPHPSAHAHTHTHPYTHPFHSPASGHVSLSDFSAASTDFGESSSGNSQSPGDHDAQRFSAMLQAWSNNVEQEAAAAAASSGSSTTQSAVATEAEDDCLLPESRARRLLEHRLMQNYLYNLGVPFPVSPSQDWNDLWTKTVPPMALRYDNILYAIMSHSATHLLRKEPRNHSLFRARQAYLVAAMRVQRRMVDTLTLDSADAVCLASLIMLVQSFAMLDERIIDTYTPPMDWLRLGKGAGAVIWTSVEAILKTGEESKSVMLTIANSQPRMGFDESYFDASNRESLNAILAQDLTSGDDWDDPETRDAYEKTLSYVGSLQLSMRRGEPIYVLCRRVQGFTMVMPPRFVDFVDERRPRALVVLAHFFAAVSKITKIFGGVWWLGGEDGRESIATREVRGIRSIMPQEWMAHMIWPMEAAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYH6</accession>
    <name>A0ABR3YYH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Choline transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006567</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF27">
        <property type="entry name" value="CHOLINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="55860" checksum="8A9C5E619F6F2AE5" modified="2025-10-08" version="1">MSLTDRSKLNDSLPHEVDEAVGVMLDTDGEFNASGHPDQLKRQYGLIRVAGAAITIDNAWVVLGSSISVSILNGGIPGVIYGFMVATFYYTFIGLSLAELASALPSSGGVYHWATMVAGPRHGRIVGFYAGWINFSAWLFALASLAQVAANALVQIYVVYHPDYVSEQWHIYTAFLGVLWLCTACVALGNGFVPRTQSIGLFLVLAGGLATIITLAVMPNQRATKRDVWGSFAENNATGWSGGVAFLTGVLNGAFTIGTPDSISHMAEEVKDPRRNVPRGILLQIGLGFWTALCFAIALGYSVTDMSVLQGGVNTFPLAAIYAQATNSAAATLCLLLIIFLSLLCCVTGTVLTASRAYWALARDCAVPFSSIFSRVNARFGSPVSATLFVSIITTGLGAIPLGSSVGFTNLTGSFLILNSLSYAIVFSANLLSRRHHFHPGPFDLGRFSVPVNVLAVLFITMFAVFFCFPPAMPFDATTMNYNCVILTGIVLLISVWWFLHANKHYEMPHLQTTVAHHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYL2</accession>
    <name>A0ABR3YYL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Saponin hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045596142" description="Saponin hydrolase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="66377" checksum="ACACB22E1ACE19FB" modified="2025-10-08" version="1">MTSMTIFIAGILGLTRAACAIEPIPSPEPISITELPLPPFLGNTSEGACTADFNPRGTGCIAQTGLNSGSFLPDGKHLTATVEFVGAPAAPDPAHIYSGQQLFIIKTDGTTFSNGDTWKCLTCGVPAENQVGATALDAYPQTFMDGTRAMAGTNIVDCGSYQLYSDDCTPDKVYIYPIRLSDTSNDNYTGTGASIRELRLHPDQVHLGFDTFVFSGPSIGEFSFYGRLQFNETGSRYDVVNASVLISTSAQSVITVNGSEVVFDPEGIAVGELRGFTGDGSEILYVGNPVESCNIDIFAIGITTGKVRRVTEHPGYADPISYSYDNNWFIVLDTRGTDRMEFLSALRTVPPVTDLLTVAAVASVRNNGVRRFFRPWLLDHDGDRGLYFGQQLNGNNNTAPGDTNDPYWNSGADPRWSPDGTRVAYYEMFAVSPACGGTNPLPCESNPYADGRQVRVMLAEFTTRTPTTPPIIPEHSDEVPWAIPYKPGMSMPTFTPFPNGVYTLYGAQGGHANVTFALGTTSSNIVVTYHNYTVDGKNVLNGYENVTSNTLSQTLSSFDWYSDLISEGTNGVGTKKTSADGFHFQIDVMTNEFVANGTLTTVVDDTTYNQPCNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZK1</accession>
    <name>A0ABR3YZK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rac GTPase-activating protein BCR/ABR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">STB5_1</name>
        <name evidence="10" type="ORF">Sste5346_006529</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF7">
        <property type="entry name" value="PROTEIN STB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="54"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="182" mass="19626" checksum="B62C8DA8DBFE4B92" modified="2025-10-08" version="1">MAVDALRDMRRDVMPEVHPQSVSPSSSTGATVTCASDASSTTLPQDALARRLVDAYFRNVNRAYPFVDREKVLRDLEMAADDGDAASGSGSGATLLYLIMAIGCTTLQRAGQISSDVAAKFHVNYTEILQECFGREEDVESVQILVLLALYSFFDPNGASAWSIVGMVSRQAILLGLSRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZN1</accession>
    <name>A0ABR3YZN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">34-kDa subunit of RNA polymerase III (C)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPC34</name>
        <name evidence="7" type="ORF">Sste5346_006200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028763">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="200"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="423" mass="46442" checksum="3D453F488733A0BC" modified="2025-10-08" version="1">MSSRAPSEDPSKLELLKDALYQAAVDNGGEGRLWSQQDLIDFDIIPEGNLDLLMKAVQGLCSDFLFKTMNDGRIGLCWRYRPVEDAAKYRTLNQDQIMVYELIDDAGADGIWARSLKHRLNMHESVLKQCIKHLEARGYIRDMKSVENIGKKMYIKATLRPSDRATGGPWYSDGVLDGDFIESLQELVFDAIRNRSTYLSRVRTPAPAAPTATTKQPKKGVVRGDASAAATGATRGRKRTADALSTGDDKKDGATNGHPSKHRTHTTRRQILLPMPAGYTEYPTVRRIAELIEQSGVAMNTTLGEADIQQLVDLLVYDGLLEPVRLPGSHETGYRALNASRLEESSANAPPGEPRTTPKGAPPPLNNGLTESPCGLCPVFDLCEDGGPVSPANCVYFNRWLGLEEAVEPAAVTVLEEDDFDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z006</accession>
    <name>A0ABR3Z006_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="73"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="574" mass="60115" checksum="A7627A7E34AD69E7" modified="2025-10-08" version="1">MADTTDKERANSTTDVDTAMDEKAPATPNGSDREATNKDNIGTPKDGDVEAATPPSPPVDDTEYPTGLKLAVLVSAAIVAVFLIALDQTIVGTAIPKITDEFHGLNDVSWYAAAYFMTFGAAQASAGKIYKYYNLKWSFLVSMLIFEVGSLVCAVAPSSTALVVGRAIAGLGGAGLSVGGTSIVALTVPPVQRPMMMGVIGAAYAIAAVLGPLIGGAFTDNVSWRWCFYINLPLGGVAAVAVLFFFHPPKKSDATLSATWKQKLLHLDPVGISLAMGAIVSLILALQYGGNSHPWKSSVVIGLLVGFVLMVAALVAWEIWLGEYAMLLPRLFRQRSLWATAPFQFFFMGSYVVLLYYLPLYFQSIRGASPIGSGVDNLPLVVTATVFALAGGAVVTKTGRAQQVMMVGSAFSTVGIGLIYSWDQNTSTGKWVGYQLFTGAAMAFAILHGLSIAQAYVDADDIAAVTANLLVFQTIGGAFSTSIGQAAFVNRLLAVLPKTAPGVEPALVILTGASELRNVFSADVLPGVLDAYMAALKAAFAVGIAFCGVAFLFSFAIPMKRLPKGAADAAMAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z017</accession>
    <name>A0ABR3Z017_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="178" mass="19422" checksum="994D5A29A99F3FED" modified="2025-10-08" version="1">MALRQVLPRASEICYGESTSLFCYKKPNGTLKNVDVADVKYIGAYLRHYGRQNPNKPAFYTMLAPDTPDCAEWGLFTRGSAQALAKHIGENTNTSVLYEDIANTIECGESPTDASRAAAIIGCLSDGGLLDVLTNASNPAYQTTDYTSSGYTSSGILCQNRGCRTGVVIYSLKWNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z065</accession>
    <name>A0ABR3Z065_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Allantoate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DAL5_2</name>
        <name evidence="8" type="ORF">Sste5346_006167</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="78"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="58586" checksum="81DCE8027A856C4F" modified="2025-10-08" version="1">MADTEESPKALEPMEVEDSKKGFTGDTAFHIQHVTKYTRNDDEALKAFAELGGEPMDIAQEMDEATNKRLLRTIDWHLMPILCLVFGLNYLDKTALSYASIMGLKIDLNLSVEEYNWLGSIFYIGFLVWEYPTNRLMQMLPLARYSATCVTLWGAVLCLFAVAKSWSGAMAIRFFMGLLEAASMPGFALLSSQWYTHHEHNTRTGMYIGSNGGGQIIGGLVAYGIAKHVPNDGTQPLAPWKILFIVTGGVTVLVGLAFFYIIPDSQLNCRWLSKRDRLLAIARVSENEQGIGNTQFKRYQLLEAFTDPLTWALFLYGVLSDIPNGGITNYFSQLIVNFGYTPLQSLLYGIPGGGVVIVSCLANGFLGDYFQQRTLVACVPMAVAVLGMLLIIALPISNNVGRLVGYYMTQTLPSVGATVLSLISSNIAGYTKKTTVAAIYMVGYAAGNIIGPQTFRSKDAPRYLSAEITILVCFSLCIVDLLFINWWCRRENRRKAAIRAQPDFIPVENHGWRDMTDRENLEFVYCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0K8</accession>
    <name>A0ABR3Z0K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="315" mass="34395" checksum="D01984365DEED3EC" modified="2025-10-08" version="1">MYIQVVYLRHPDGQRIAAHWNHQQFGGLFDFRRSPHSSHGPHLQRSAQRPYQAEPKNDTSVVQHGDIYELITDDPDSHPLPSEHFLQVQYAAHTLMSGMRAAGALKDTFSGAPPDDDDDDDDAYADATIPCPSVPAYWLVLVKEAQDLGILNESAATRWSRAFARQAHQDAKDAAALEAAYLESQLNGDDLLGEPDLKDDTNDDGPERKRRAMLADVVAASPGTAHNITMSSADALKPSLARAMLPTVVNEVTVQGDSQGVGNKHGRLRDLFETWKKRGKNGAISLGRLDFGKKERAPVKGIFIGTVANNGAGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z188</accession>
    <name>A0ABR3Z188_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF2">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185403" description="FAD-binding domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="435" mass="48049" checksum="00F7E5D00DC33870" modified="2025-10-08" version="1">MPLNILIVGCSIAGPALASFLQLAPFPHNERPEITVLERATSVRNQGQNVDIRGVGVALLQKLGIEHAVKTSTTGEAGVQWVTSAGKVWAELGSANDGETGRHNPTSDIEILRGRMAQILWRRSQTITDDSAVEYIFGDHLDGIEQDHTANTVTVHFAKSGKKRTFDLVVGADGLQSTTRSMVWGSKHEAECVHPLNMYAAFFSMPRDEAAGDSEYRRCYHTHGRRLMSIRPDQQNNRSTSLLTVINDKDARLGDVATGHGKAVVAAQKELVQEYFADAGWQAPRLMREMVATDDFYYSMVAQVKMASWHRRRVVLLGDAAHCASHLSGMGTTLALLGAYSLASALAKHSKDVDTALSTYEVEMRPHVDKAQKLMPGMLRVLSPETAWGVWLVDTTIRFLVWSRVFLLLFYFKGPDTEPDGLPEDGFTLPPVYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1F2</accession>
    <name>A0ABR3Z1F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="6934" checksum="1E04D3B70E472987" modified="2025-10-08" version="1">MCCHNSEAQAVQVVARRETVYTWNCHRCGETGNSDSHDHCTHCDHRKCSDCSNEKTSVTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1R9</accession>
    <name>A0ABR3Z1R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="397" mass="43292" checksum="BA14220B69B776D3" modified="2025-10-08" version="1">MASLAQSSTATGEKRHRFSFLHRSHKRSSESLSTLGQFDAVPQYEKHVSNESNSDDDSASVTGSPPNYDTLYGAAHSTDAASIAPSAEGTFRPTLELQLDTRGKSQSESYGQIPRPEPIHVFMVNSRDGSALYNLQPVYTSLREKRNSNSCTLYAGAGYGMLHSDRASSSSQNRTLSTTTYRIGPGRPPRIALFDANDIRLDETNAWDYFEFSGKSIFNRVQILRSRLGTFEWRYASRDERKALSAELIAAAAAAGSTLNEKDIKKRYSVNNLMVLERVTHVFGSIDNNNGGASSSAAVGKPREVRRPVARLIRSKALRTPGSNRFAAGNGGRLQLDLSEWMSAANEAAAGDSKVAAPGSDDQADRDMVIVLAVVTCISMLKKEVDRRSDQEIAAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X0</accession>
    <name>A0ABR3Z1X0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_005828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="151" mass="16782" checksum="B07F62D529AE2435" modified="2025-10-08" version="1">MARRLLTQMRSVSRKTNMRVRPAVKHRVCKFCDTLLVEGSTCTSVVENHSRGGKKPWADVLSVTCTTCGRTRRYPVTTPRQPRRPFRGDGTGKVEEMDVDSKVAVTSKAHKNQQQGKKQDQKMVVVSRGKEQQGTMAAPAKKGQNSKQSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z246</accession>
    <name>A0ABR3Z246_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF1">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="112"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="380" mass="42689" checksum="5CBCD8DCE26F555E" modified="2025-10-08" version="1">MDRRDKQRFAVPASPVSWSGSNTRGRPVSTNTGPSTTTSRSRSGGASVEDPDYRRLLLKNNIDLRPDYLPMPGHVESIVEHVRTRQRDSPERTDEELVYDEKRWELFEGTGEDEVVKYYSKHVFPDEDGNNDVLRVRTGKSMARQVVPFAGGDVAPFCVPAPDMLYGYRADRAFPNPAHREKLSGDMEKEVIAINDIGSRNALLYPFFIVEYKGVGGNMWVATNQCLGGTSACISIAEKLNRRLFEAAHAKDGVVTTVDSTAFSIAMNGNEARMYVSWKQDELNYYTTNIDCYALRRPDEYRRFRRMVRNVVDWGRNDRLKGIKKGLDQLLEAAEKQTPDIPDPALSGIPGSSGQSVRQRSPPSPSDKGSSSRRSKKQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C2</accession>
    <name>A0ABR3Z2C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MHF histone-fold complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MHF1</name>
        <name evidence="5" type="ORF">Sste5346_005726</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="108" mass="12151" checksum="C23C36D3CC08A611" modified="2025-10-08" version="1">MANREEQELKSALWSAVSDLVDQESIKQNRNATPQFIGALADMVWTQIESVAIDLESFSRHAGRSTIKTEDVLLLARRNEDLHDILKEMVDERKAASAKTAKKGKQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F3</accession>
    <name>A0ABR3Z2F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Brl1/Brr6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040202">
        <property type="entry name" value="Brl1/Brr6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018767">
        <property type="entry name" value="Brl1/Brr6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136:SF1">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRR6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10104">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01042">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Brl1/Brr6" evidence="3">
        <location>
            <begin position="310"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="560" mass="61926" checksum="64996B6F8885FE81" modified="2025-10-08" version="1">MNRRTFESHMDWEYQNNRGPVDVSSPFSQIPQRPFMGPSFGSSESPSRLTRSANPFANIGNNAASSTSSSFANANPPSPSKQQFPRPPSSSIFNPPSTKSYPAASPFRNPSFTTPQKRQEEIFSECSGAEDSPALQSDVSMAAEETPDYERIDREFAHATITPASAVNRKLFHDENDSPASPQYSSSQQRQASPSRPTSSHASGRGAVPRGKLGHFFGRRDRVRKRKRQVGDKDVGSVRSRHHNSNYSSDESDDSDASEFTDGDRTERRRGGDKKGRRAAQGEDGTTVKRGAIGNLFSAIHDHPNVPLILSWWVQLGMNVFFMAVVMWFVWGGISMMRADISHAADAARSRLLAQMNDCAHEYTKNRCAPISERLPALNVMCNEWEVCMNQDPSSVMKLQVSAKNVAEIINEFVGVMSFKAWGFILSAMLAVILASNMGFSRFRDAAFVDNHAKPNMPSQHSYSQPQPGPSSLPSSQDPNQAYIWAPIGQTPRHIRREFMLQPDTPTDTDGSPDVPRAAIMPPPQTPSFRRSPSKGERERSPTKADRSPTKAGRSPSKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z349</accession>
    <name>A0ABR3Z349_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SOH1</name>
        <name evidence="10" type="ORF">Sste5346_005481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="123" mass="14272" checksum="D7459913B0B79895" modified="2025-10-08" version="1">MATYGNNVPPSLQTANGAGNGATTDVQQTRFEIECEFVACLANPYYLQYLAAEKYFDDPRFVRYLAYLEYWRTPPYLQYLSWPGPTLRHLELLQEESFRQAIISPEVVMRLEQEGIQAGFYWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z368</accession>
    <name>A0ABR3Z368_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF86">
        <property type="entry name" value="ADR321CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="551"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="565"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="669" mass="71532" checksum="32F7910678089CDC" modified="2025-10-08" version="1">MGSLGGLSPGGSIALGIVVGVMSTSVQSLGLTLQRKSHILEDEKDPHIARRPPHRRRRWQLGMAMFIVANLLGSSIQISTLPLPVLSTLQASGLVFNSICATLILGEPFTRWSLYGTLLVCSGAILIAIFGAIPAPAHDLDELLELLVRPAFVAWMSLQTVIVLVIAISVEVASSLLFKSLAQTSRFRLARGLAYGCISGILSAHSLLVAKSAVELVVRTITDGNNQFRHWQAWALVLALITLALTQLYYLHRGLKLVSTSVLYPLVFCIYNIIAILDGLIYFRQTDMIGPLRACLISLGTVILLSGVLALSWRLSDEQHPPAVGQSSLAPGLGLVEDTEGEDDEETLLLGRDMVTADGDDEERNIEGNGVGERRSLLGKSKYVSSYQTFGFGNLENGDSPARSEGEPPVTHPTSPKLGRRQTAAGVFGGTNGPTTPGLHTPSRWTERAEIWDELEDTTNDRRPGSGGSGMKRHRSSTLPVLISEQPPHTPTATSNSPLSPFSAARRGVSSGSPSLLRSTNPETFRVPTGEDADAEALAAYRKSFRRRRKTTGFPGFHARRGSRRSLSGSFSTGASGVGTGSGSNETPPNTAETRSTSGVQSALGGLWRMGWWNSDSNGGGDASRPDRPPTQETVSSPILPHHRPAGDEEPTPTSHTDSHGEPGGMDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3H5</accession>
    <name>A0ABR3Z3H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spore coat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="10211" checksum="E0CCF249D0F729A5" modified="2025-10-08" version="1">MCFGPPRRTYYQPDVMVMGPRPVVRPVMMPRPVMMPRPVVVSRPPVVVAAPGPRMGYGGGYGGGGRHHGGPGYGGGGYGGGYGGGRYGGGGRMGGGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3S6</accession>
    <name>A0ABR3Z3S6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonylcarbamoyl-AMP synthase</fullName>
            <ecNumber evidence="3">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_005710</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00057">
        <property type="entry name" value="L-threonylcarbamoyladenylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="14">
        <location>
            <begin position="49"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1894735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="453" mass="47804" checksum="71B02851484B236B" modified="2025-10-08" version="1">MYTTRILPVPDPDSLGRFRPLPAPSSTTISSSPQSVLDHWDAAESAPGLEALVTAADHIRTTDVPVGFPTETVYGLGADATRTDAVRGIFSVKGRPSDNPLIVHVCDLDMLRGLLGDGKNLPDIYRPLVERFWPGPLTILLPVPSSDSSDAAGAPKWTLAPEVTAGLPTFGARLPASPLTRTLIRLADAPLAGPSANASTRPSPTTAQHVVDDLNGRIEVVLDGGACGVGVESTVVDGLCDPPVILRPGGISLAELRTVPGWERVERAYDDVAQGGNRSKGVAEKKEEEELKPRAPGMKYKHYSPKARVVLYEGWRAVNSSTLSQADLVADIGSAGQQAGTVGVVRTSTWPALEGLEKRSAGTTNGNITSAESNGDGAVTYNLEEYTLPFGTAVLELDLGRDLSSIAHGLFSALRDLDARGADVILIEGIDDRGDDMAAAVMNRLRKAASEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z481</accession>
    <name>A0ABR3Z481_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025444">
        <property type="entry name" value="Monooxy_af470"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13826">
        <property type="entry name" value="Monooxy_af470-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34953" checksum="507D3B9BA8EDB166" modified="2025-10-08" version="1">MDDNMDDNIDKTGGEPRLDIPPSPPPDGYDFRSLVPPTTVRPVKWTEIGPAHIIKDAFKLHTLLAIGAGLQMAFAAAVPTPWCMLPAAALLVLAPTITVVQILLPTIRFRGRRLTHPFLSGIIPGRSTAHIPSPTTGRYSPHPGQGLVVFHFGARFNHPLGVFAPGAQAMTRRFRDTLASLEDKRTEYGLLGGDLFRGGNAARTSNDTILLVLDFRDVSGLQRFAASPVHREAYEWLRQTTADGKYSHLSAFHETFVVPAGHYESLYINTAPILLGNTHTESDSERSEDTERVWLSSLVDADDERLRTMTARLKRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P8</accession>
    <name>A0ABR3Z4P8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">AdoMet-dependent rRNA methyltransferase spb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SPB1</name>
        <name evidence="12" type="ORF">Sste5346_005387</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03163">
        <property type="entry name" value="RNA_methyltr_E_SPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012920">
        <property type="entry name" value="rRNA_MeTfrase_SPB1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024576">
        <property type="entry name" value="rRNA_MeTfrase_Spb1_DUF3381"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028589">
        <property type="entry name" value="SPB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF13">
        <property type="entry name" value="PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11861">
        <property type="entry name" value="DUF3381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07780">
        <property type="entry name" value="Spb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="9">
        <location>
            <begin position="23"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3381" evidence="11">
        <location>
            <begin position="233"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase SPB1-like C-terminal" evidence="10">
        <location>
            <begin position="647"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="443"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="828"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="578"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="846"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="859"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="871" mass="99004" checksum="3C40D0F89FC674B8" modified="2025-10-08" version="1">MVEKKHGKGRLDKWYKLAKEKGYRARAAFKLIQLNKKYGFLENSKVVLDLCAAPGSWCQVAVETMPANGIIIGVDLSPIKPIPKVITFQSDITTEKCRATIRQHLKNWKADTVLHDGAPNVGTAWIQDSFNQSELVLQSMKLATEFLVEGGTFVTKVFRSKDYNSLLWVFNQLFAKVEATKPPSSRNVSAEIFVVCRGFKAPKRIDPRFLDPKAVFAELADPTPNNEARVYNPEVKKRKRDGYEEGNYTLYKEMPASEFIQTTDPIAVLGQYNTLTFDQPKNGDVALAALAKMVETTDEIRRLCTDLRVLSRKDFKMLLSWRLRVRERFGFPTKKTVVKPLSEEAAANVDDMDEETKIQKELQDMRDRANSKTKRKKRRDNEQKQKEIVRMQLNMTAPMDIGMEQADAMGEGALFGLKKIDKTTALQRIARGKMATINPEKAIVTAEDGAEDSDSGIGSSAETDDEEDDEEDRLERELDGQYDQYQERRAAVDAKHRAKKAREHGDDAEWEGVSAGESDIEDSDGDLEEDSSSDEDEPSARGITKSLLTDLDNSAPDKSGLSKRAQDFFARSEFADIMGDDLEEEEEEDEEEEEEEHEEEAEDEEYEEVKDAAEVEEIEIDEAEEDEEDEESDDDIMPTKQEVGSDDEDTGNFEVVRRPRRDDEDEDDWEDEDKRRAAADDKVGVDIITAEMMTLAHDLALGRRTKQDVVDDLYNRRAFRDKDGLPDWFLDDESRHDKVQRPITKAAADAIKEKMRAYNARPIKKVREAQARKKFKAAQKLEKLKKKSEMLMADEGMTEKEKGDSISKMLGKAAKKKPHIPKKVVVARGSNRGIQGRPKGVKGRYKIVDPRMKKDTRGLKRAAQRGNKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4T6</accession>
    <name>A0ABR3Z4T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="141"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="316" mass="35668" checksum="EDD9729FF511C9BE" modified="2025-10-08" version="1">MDPVAELITSYFELNGHIIDELDDGGTEPSPLEFMRYVARNTPFVVRRGASTWPAVQNWSVPFLKKTLVEHTVNVAVTPNGFADAPTPGPDGDVIFAKPWEEDQAFPEFLDYVVKQEKGQLPKGAETRYAQTQNDNLRHEYASVFAHVHKDIPFARIALQREPEAINLWIGNSHSVTAMHRDNYENIYVQVLGQKHFVLLPPLCQPCVNEQPLQQYNYKRSSDSLTMEKEELDSEARQEGDGGDNTVPFAVWDPDAPDDNTTTYSSLAEPMRVTLNPGDMLYLPAMWYHKVSQSASEQGICVAVNYWAIITTDNFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5N4</accession>
    <name>A0ABR3Z5N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="66"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="563" mass="61748" checksum="5AC0C07EB839C745" modified="2025-10-08" version="1">MEKTTDPNPPTSSPVAADATATDAPNIANAWVGLAGLNADARDATEAEHRMTLRDALRLYPKACFWSVVVSLVVIMDGYDTALIGTLFGFPAFQKRFGVAVPGSTTGYQVQAKWQTALGLASPLGNLVGIFLNGVFTERWGHKKTLLGAMAWLTAFIFLAFFAPSVGVLFAGELLCGISWGIYTTLATAYASEVTPVVLRAYLETFVVLCWGIGQLLSYGVLDGLTGNKTQWAWRIPFAVQWAFPVIIVPLVVFAPESPWWLVRKGRIEDAEKSVRRLTTANGASSDEIAATARNAVALMVETTQLERAMTEGSSWIDCFRGANLWRTEISCMAWLSQVLVGFAITSYATYFFEQAGLQSSDAYKLTVGLGGLHFCCTLSSTLITARHGRRPIFMTGAISMSLVMFVIGFLSVAQDTRGGSMRSYGFAGAAFYFLWYACYQLTIGPMAFIIVAETSSTRLRSKTISLARNTYNIGVICSSTVAPYVLGSTEGNWKGKSGFLAAGFSLGIFIWSYYRLPECKGRTYEELDVLFAKNLRARDFASYQFDREVEVERKMVDMEHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5T2</accession>
    <name>A0ABR3Z5T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sphingosine N-acyltransferase lag1</fullName>
            <ecNumber evidence="10">2.3.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lag1</name>
        <name evidence="10" type="ORF">Sste5346_005561</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.24" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="161"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="424"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="57259" checksum="D9B612FBED38F787" modified="2025-10-08" version="1">MAAVASSARPTAVPLPPHLKRAAHANSKPTASPINSNSPTPSFKAQTSSNALPLRRKRKQETPMKQFTRWLVNNQTGLSANLFALLILTHTLFPRAREHTSKFFTLSYFNPATGHYNLGPDDVPFVLFLIVLFTGLRASTMDYILSPFARSQGLYKKKPITRFAEQAWLVIVYTVFFPLGVYLYFNSPYLWNMKNLWTHWPSREMPGLLKAYILVQLAFWLQQIIVINIEERRKDHWQMLTHHFITVSLIAASYRYRHTPVANVILMLMDISDFFLPLAKCQKYLGYTSICDVTFGAFMLSWFVCRHVFFSMICYSVWAQTPNIMPVGCFKGSSSGSPLGVPVGPNEISSLTPTISKLVPFLSDATSNKLAFLVEPLVDSEGAVCYNPAVKWGFLSMLLFLELIIIVWFFMIVQVAIRVVRGNGADDTRSDDEDEEEEGEDVEGDEAFDGGVAAPLEEEVGVEALDLKGWERRTGVKRAASTTTSVSLPGHHSDRKELLNRIGCEKQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5V8</accession>
    <name>A0ABR3Z5V8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine O-succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cys2</name>
        <name evidence="4" type="ORF">Sste5346_005591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.31" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF16">
        <property type="entry name" value="SERINE O-SUCCINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="158"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="568" mass="62032" checksum="4164E2A7FCC345D4" modified="2025-10-08" version="1">MKVTQSLAGAGMRSSARLAVDGSSQLARRSFCTQRPAASTLFSLSFSQHPQRRSLHMTAAQKSGASNPAMAFPCLDALEDRSQRLQSERQQQQQPLSTTTTARSSRTSESGPEPNYTSGATLRYHCEEPLRLDWGGVLREFDIAYETWGTLNADRSNAILLHTGLSASSHAHSTDINPEPGWWEKFIGPGEGFALDTNKYFVICTNVLGGCYGSTGPSSIDPADGSHYATRFPILTMEDMVRAQFRLLDGLNIQRLHASVGSSMGGMQSLAAGVLFPDRVGKIVSISGCARSHPYSIAMRHTQRQVLMMDPNWNRGFYYGYGQVPPHAGMKLAREIATVTYRSGPEWEQRFGRRRADPSKPPALCPDFLIETYLDHAGEKFCLTYDPNSLLYVSKAMDLFDLGAAHQARSAQRRREREAQEASEGAAAAAEAASGAAVCTLTLPDKPYEEQPEAGQPTAAQALNSSPPPSETDSHVASMMPGAPSWQPPQDLVQGLAVLRNHPTLVMGVASDILFPAWQQYEVAEALKMAGNRNVSHYELSEQQSMFGHDTFLLDLKNIGGNVRNFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6H3</accession>
    <name>A0ABR3Z6H3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="114" mass="12459" checksum="20D2BE5A0597B17E" modified="2025-10-08" version="1">MGEDFDDAEDENAPGSSAMSLFKEFTAVSKFTVSVELLGWRGAGAYNFKGNTAADTARVAASIIAQSPPNMGEFNCFTSMLVDDTDFLNDMDSYRERSGRSTPRSRYVIAKDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z786</accession>
    <name>A0ABR3Z786_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="23461" checksum="899AA56BB81C378B" modified="2025-10-08" version="1">MNRALHRVNKKAQLMAAQAAWAPAQAAYQVPASATPAPENLYQQYPMAELNGTGTPKTKAPTLSSFTPVQSSTQSPLRPPAAELAPNLPAVPHPIHEIGSCPKQRLAIKDETDESISRQMVEIQAQLQLAASLRTNHHVGHAIVELFTPRNIRRTATAIIIMQIIIFSGALAIQNHQSLLYANLGFTDKQALLVSGYYGIMGIVGQIINLLFVSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7B6</accession>
    <name>A0ABR3Z7B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004806</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF6">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="87"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="599" mass="66330" checksum="75E558E70E8BCBF4" modified="2025-10-08" version="1">MSPPKYEEDGGLRPAPSNDEIAPTYSNSGNETDLGDGKYTNEKIGPVPSSPNMVGDIRRNSSGGSSADRLVENNNNMLQRRLKNRQIQLLAIGGSIGTALFLSIGNGLIRGGPGSLFIAYTMYSCILGLVNNCIAEMTVYMPISGGFIRLAGHWVDDAWGFMAGWNFFLYEALLIPFEISALSVVLTYWRDDIPAAAICAAAIVAYILLNIFAVKTYGEAEFWLSIGKLILIFILYFFTFITMVGGNPKHDAYGFRYWKNPGSFAEYLSTGDIGRFEGFLAAVWSASFTVVGPEYISMAAAEAKHPRVYIKTAFKTVFWRFGAFFILGSLCVGIVVAYNDPLLSSGAGSGTAAGSPYVVAMTNLGIKVLPDVVNALLFTSIFSAGNTYCYCASRSLYGLALEGRAPRILTKCWNGNPLLCFAIVICFSFLSFLSVNSGSNVVLTWLVNLITAGGIINYVVITVTYICFYRAMKVQGFDRSTLPYIGWFQPYGAYIGFFWMSFVVIFYGYSSFRPWSVDNFFTYYTLVILAPILFCGWKLIKRTHWRRPHEVDLVWETAAVAAYEAQETEPVMGLWEEILELVYIRLPKNKKKTEVSQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Q7</accession>
    <name>A0ABR3Z7Q7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial thiamine pyrophosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TPC1</name>
        <name evidence="12" type="ORF">Sste5346_004648</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="12"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="126"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="225"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="337" mass="36406" checksum="76A291876C6459B6" modified="2025-10-08" version="1">MSGKGKRLQDEGTRMQVVVAGGTAGLIARFIVAPLDVVKIRLQLQSHSLSDPLLFARRDLNGGPVYKGTLPTMRHILRHEGVTGLWKGNVPAELLYVCYGAAQFTAYRATSIALERFHEASGIAPKPHVDSFVAGASAGAAATAVTYPLDLLRTRFAAQGNGPDRVYTNLRSAVRDIARDEGIRGFFRGLGPALIQIAPYMGAFFACYEGLKPVTGQLAGQVGQSLGAGDAAAGVVAAVAAKTFVFPLDLVRKRIQVQGPTRNRYVHKNIPAYDGSVVRTLQTILRTEGMRGLYRGLTVSLMKAAPANAITMWTYERVLHILIRLDDDKKHTIQANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9T4</accession>
    <name>A0ABR3Z9T4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translational repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SSD1</name>
        <name evidence="3" type="ORF">Sste5346_004157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="781"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1225"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1249"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1276"/>
            <end position="1290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1403" mass="153493" checksum="ADCF25A6BEE7042D" modified="2025-10-08" version="1">MDNQQNPPTGGVPGPTGRRLHIAHRRSPSEMTPLVSMYTNANMTPAMLQQQIEALQQQQQQLQHFASLNGGMLPNQGLAAGGAFPMQPVNMSPQAGFQFPAQQQQQQQQQPQQNINTGILPQQQTHSHRRNQSALPGMGMGPPPAPSSGASGSAFGNFESPAHAREGGGPSSRGGRGGGGPGGGHQRRHSLVVADARKAAEIAQQKRTTSAFQFPAPSSSSPNDNKTEGSSDVVVDGQSGQSSNPTPPPAPPAAGRGRGGHGRSQSMAVGRGGGGLGRGGMGNYQADSLSGTHDFQRRGGGSHARTNSRNFDSNWRNQASADGNNNGNNNGGQGQQQQQQQQQPLQPQQPQQGFQPGHRSRASVGGGQSISSINAFPQLMQLPNGQMMIPGVFPGQQQINPLNQLQLSQLQAMQQLNAQQFLGLQNSQHAAQGGQNQQNPNQQQQRKTLFTPYMPQASLPPLLSDGSLVQGILRVNKKNRSDAYVTTIDGELEADIFICGSKDRNRALEGDLVAVELLDVDEVWSQKKDKEDKKKRKDITDTRSGSTNGNGDGNNGSGINNGGGSLNNGSGEGGIRRRGSLRQRPTQKKNDDVEVEGQSLLLVEEEEINDEQKPLFAGHIVAVVERIAGQMFSGTLGLLRPSSQATKDKQDAERNNNPRHGDNRNQDKPKIVWFKPTDKRVPLIAIPTEQAPRDFVEKHQDYADRIFVACIKRWPITSLHPFGTLVELLGHMGEVKTETDALLRDNNFASDEFSDAVLRSITTDWGTSGPAKEDAADLEGRRDFRNEKTFTMDLDGSPNLGNAVHVKTGTDGKIEIGVHIPHVAHFVKSGSLVEREAKKRGTSVHLLNRTCALLPPRLSTDLCSLLPEEDRLTLSVVFQVDAHTAVVADEDIWVGKSIIKSNGKLSLSSMNEALTKGDSFESAAASAKDIQILRLVTDKFREARLGSTDEPMAPLRLIQQLDDENIPIEHNIFDTTPAVELVEELMHKVNAHIAKLLVEGLPKQAILRRHATPNPRRLQTIVERLTALGYDIDTTTSGTLQNSLFKVEDSDIRKGMETSLVKSMQRAKYFISGDKRQQLWAHYGLNLPVYTHFTAPTRRVVDIMVQRQLQLVLAKETEGYEDDSLAKTVDMCNVKKDSAQNAQEQSVHIDSCRIMDKKRLETHGDLISEGIVLCVYESAFDVLIPEWGFEKRVHCDQLPLKKAEFRKDKRVLELYWEKGVTSSSYVPEDERVKSGPSTRMRNAATAQQQHEEAERQRREREEAARRQVDTGTISTDDTDALFDDDEDNDGGSDITEAMAGASLAERPTQSVPGSPSRLDVAGGVGESSIQRARSDSRVPASDQSPESRLTDKEKYLKLFKLREEGGEYIQDVTEMTRVPIILKTDLSKSPPCLTIRSVNPYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB48</accession>
    <name>A0ABR3ZB48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromosome transmission fidelity protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003747</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CTF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018607">
        <property type="entry name" value="Ctf8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605:SF1">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605">
        <property type="entry name" value="CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09696">
        <property type="entry name" value="Ctf8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17567" checksum="FBF7D0A8AD6D6DD5" modified="2025-10-08" version="1">MDDSSTVTIYPWTPATTTATTPNALPTLLQTPAGLALLELQGTINLPEAPRHDGDEEGGDEPSENLQHRVPIGRLDFPDYDPAAGADSTAWMRRVHLYVGPHQRLTGEVKKLPRPLAVVRRRQSEDKNTSETDLEVVEVIHYKLLFSQRPEPMTESAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCY9</accession>
    <name>A0ABR3ZCY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14076">
        <property type="entry name" value="STKc_Kin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034674">
        <property type="entry name" value="STK_Kin4/ppk1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="309"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="259"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="627"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="674"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="876"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="759"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="826"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1073"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1124"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1210" mass="130970" checksum="6787AC0C364A85B0" modified="2025-10-08" version="1">MSSAALQSPAGLPPSTRHYTSSHASPTREVYHANQQQQQQISSASPSSSSRPSRSSSAGGQNGGYTNSNYISNNIHNGAGSAHMSQTNSPMSSRAALSSPAAVPSAAVNAAAAAISDYTQPSPASSERRRRHHNPPVAPPRTSSQQQHQSMSGAPSSSSSSRRAAAAAAAGSDSPRARTRETRGDDSARRRQQEQEYAQRAAASGSSRSAAATTLPIRNHGSQPSSHGPSRETSEILNSVMVSRDEVDVEREKARLAMVQQDDDYDEAAPPPVVPTSSAPEQHHDESRRGGRSRHDHSRREKQIKFGEYILGNTIGEGEFGKVKLGWKQEGGVQVAIKLIKKDTLGNNPTRMAKIKREVNILRQLNHPNIVQLHKMEESEHHYGIVLEYASGGELFDYILNHRYLKDHAARRLFAQLISGVGYLHKKGIVHRDLKLENLLLDRNRNIIITDFGFANTFDPTEELTEDEEINLVDREYIKRMGFDIVKPNGMRKADLMQTSCGSPCYAAPELVVSDSLYTGRKVDVWSCGVILYAMLAGYLPFDDDPKNPEGDNINLLYKYIVNTPLTFPEYVTPHARDLLRRILVPNPRQRADLFEVARHSWLSEYANVVEFITSSTTSSADIQNIPASAEDMDEGPMLGRSSSVREASKKAVASPTIGGLISKAGNVDPESEAAMLKQQKDNKRRTVQVEYVAPTTQTQRGGEAASSGGKTRARSSSQGPTAVNPAAGPGSPNDKPLPRDPPTGKSSRDARRPPSAHRTTGTAAAVAAAATGAGSTRVSRDGTRAVSEAAYMAQGSGGRSVTGGSNPRTAPNRASFGQPVPPTVAGTNAQGRIQQPKSSGGRNYVISNPIPQDSSTFGRPSISVPSKFAQVSGFADGESENASTGKPQTPEVKGHRRSNTIGDITDKLLGRSGSIFGGKNRKKPDQRQSVGMEKASRRYPPVSMSNSAAIQGGAAPSDEPRASMDSTARQSRRSFSLGLGKKRSGSIEGSQTSHEKQHSRRFSLLPGSFSLKSIGINKDYDTGPESQIDLPIQEPPPDVRLGSPSDSLEPAFDGMYTHLSESQQAAADSGRLQQQSLQQQHQQSHAIQQGRPILHYPQPPQQPQHQRHVSASQFERQRPSALQEVTDNVQRNPPRSAPYQGDGETFDPRRANANPRGGRVVLQKNKRMGDAYDTDEFAKHHGDRSGSSGAARRVMDFFRRRAKARGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD49</accession>
    <name>A0ABR3ZD49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF1907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003504</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17298">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015021">
        <property type="entry name" value="C11orf54_DUF1907"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13204:SF1">
        <property type="entry name" value="ESTER HYDROLASE C11ORF54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13204">
        <property type="entry name" value="PTD012 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08925">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01168">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DUF1907" evidence="7">
        <location>
            <begin position="21"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="315" mass="34657" checksum="26C19B02CBCB2777" modified="2025-10-08" version="1">MPWDTKKYELNPPSLDELAAVLQTGLEQHFTTVSVQVTHSPDLREAPFHLASEGISGHERIGDVGGPQNLRPLPRLDHKYHLRELMDLMEMQDGLVIGAGAGPFHHTGVNTELMPNLSYKNGAANNQTRFAKIVPATEDDTVKDIATGTLAHRCAPLPTSTDSALLTNLYGSDGAPGDVLKIVAKGRKKNSPDFTATIQEALRNKYEQPVSLGGVFVFRAGRALLHVMPDFKKEPRLPGNKDNWLKYFDVSAPLTCLSVVHSRDPGLKLHLEHTHCFSERGEGGHFHHDSTPADAEYEAYFNTAKVIYRIDGPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDJ7</accession>
    <name>A0ABR3ZDJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_003735</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF40">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="212"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="588" mass="63254" checksum="E586FA631F326D33" modified="2025-10-08" version="1">MRRRISPVRRRRCWTRPGVVVLCLLAVCYYFLPYDSTLRLSVRFNSQRVVNTFAAPPKSLEAWTLAPLGNATNPSNSLPAGGRHLPALYDDVGVILKTGYGTQHRVGAQIDALGLRPHSVDADNMVVIGDWAGEVVYGDKGQQITVHDVIAPVLDSGILGSRANCARAEKYRALAAAVRAGDDAEAIRISKSSGWELDAMKFIPGLELAYQTMPNKNWYLLLDDDTFVIPSSLRLLLAHLDHTVPHYIGNAVGDFRGRFAHGGSAVVLSREALTLLLGSGSSRVLAAAASNRKNSGTANSYSNGLAPPLLHQAYVDSITETWGDKLLATTLMRVGVYLDERFARLFNGARPSATRISADRFCMPLVSFHALAQPEQMRSVGAIFEQIDSGKRGGTPGDGTSPGFLAPAIAWGDLWAIYGRPTVAALHHQPIHRGRDFVGVPGDDSSSSALVTSTTENVGSPEACRVLCAGDDGEGESGGADNLQRRFAGLYSYNSKCLAWTWNAGEQTCTTSPWFVVGEEDVEKSTGAPLPANGEAAKATTETTSTKYSGVNVALLRQLVGRCGHRDGVAWMERDGVYEYAYSPNGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDS3</accession>
    <name>A0ABR3ZDS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050226">
        <property type="entry name" value="NagZ_Beta-hexosaminidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480">
        <property type="entry name" value="BETA-HEXOSAMINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="6">
        <location>
            <begin position="29"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="428"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="616"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1078" mass="116316" checksum="6ACCC0AE0AAC4BA5" modified="2025-10-08" version="1">MENQPAPMTENDRKATLGSVFLMGFEGTAVTQHIRTLIEDYRLGAVLLNATNFVSAEQATQLIRELQSVAHAASHEHPLLIAVDQENGIVRSLVDSRWITQLPSSLGVASTRSATNAYEVALATGRELACVGVNWVLGPAIDVILDRAAPGLGSRAFGDDASEVAKLGGAYIRGLRDAGVASTAKHFPLGGTLRFDESSTTVPVVFNSLDQLRQKVIMPFQEAIREDVDAIMAAGVAISSIGPKLMHACFSKKVVTDLLRKQLGYDGVTVSECLEMESISDHIGVGQAAVMGIHAGCDILTICQSLPPQLEALSALSLALDNGALSWGLVQKSAERVQRLRARHTVWQHALNPPGLAQLAVLRPSHRTLAARVYEESITLVRDNDHCIPLSNVLTEHSTILVLSPILHHRIPAADKYHMTSGNVMDDITVAGSGPSTSDNGNGGGGRNNSASYTSGSTSNSNSYTNPPPRRRKTQPAPHGQGLFYGEDYFQEFGRQLASYNFGDIVHTSYTSHGVRTEHEKLIERADAIIIMVADANRNQYQLGFAKHVAALSSLQRHLRVAAGRKPPVVILVSLSSAYDVPSTPDSPFPTHICTYDSSTVALHCLARVLGGDITPNRRIPGIQPPDADDDDAGRPHGHDHTIHQQAWLVERFDLIRDREPFQEFIRGLLETDDALLFRRLEEDTCENDDDDDEEAPRVGNAYADAVMTAGRLAPSYALPASHRSSGRGTAQHFVIRNTSTGAIYGFASALAFPSLERGCISALLVDPEKRELAMGRDLHRSVVRHLSQMAYGITTVQLGAPLTAMFPGVPLDNDNSFPDNVEFFKKMGWNLESSQAQRLYSLLYKQPSPNTADLAQWQADAAAKGLVLEVHSNKTRSRTSHNTSPWSAILEFVNTAQKLPKVAAEQPFAQLIYREAIRAALAMPIDGGDCSSAGSSGGSSGGSDSSDSHGIPPIVVLAVREQFSGAIVGSVLLIRHGSPPNDFAAFNFPHPCRLPPSTSTAVLMCPIVVPQQNETVDSHKTVVHGLAAKAILTARRSGTPSILAHAIPKTMLNALEETGFRVDQVFVMAERPIGDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDW1</accession>
    <name>A0ABR3ZDW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="309" mass="33698" checksum="C448DA2AFA894ED5" modified="2025-10-08" version="1">MSTQTLYVPHLGGIDVGYRLSQSVIDRTKPTIVLFNPFTATTDYYEPEFQNPALCAAANLVAVEPLGHGRTMPRSGTGTTFTYWDSAHMALQLLDALGVDKFFALGTSQGGWIAVRLALLAPIRVKGVIPVGSSMDGESAESRALGCWDGPGATSGFVSQAGAPTDPAADADFVPGDDYYDFLMEIGFGVTVTPQIRDFWAKTIARNYHGEAGKRRIIMAAVALATRDSIRERLPYVRCPVLWLQGTSDVVFSLKQAESDLPLFTHSVEARLVPCKGGVHFLSHTHKDLLHRELLAFVQKWTRGAWAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHC6</accession>
    <name>A0ABR3ZHC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="104"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="548" mass="59154" checksum="0C2F29B57EA37BD4" modified="2025-10-08" version="1">MNADQQTEEKSAFNDNVNGSTPNNSKQTDISPNNAEHQPDTECDDNGGNDVKDDQDVSRGEATPDDSDAKKGTDGDEDDQYSVSWGDQPDENPMNWTMGKKWRIIGTLSVLSLLTPLASSMMAPAVPDILQQFEVHNDQYGTFCVSVFVLGFAFGPPVIAPLSELYGRTIVYHVCNSLFVLFTIGCALSNSIGMLVAFRFLAGFAGVSVITIGGGTIADMVPPEQRGKSMAAWSVGPLIGPVIGPVCAGFLVEAKGWRWVFWVIAIAAGAVTAVSFFVFRETYAPVLLERKAAKIRKETGDPNYYSKLRVEGTRSQVITSSMLKPIRLLLTEPIVTCLCVYIAIIYGVLYILFTTFTFVFEETYGFSARGAGLSFIAGGVGNLLGLVFASSMSDRIVQRRKASGSPPVPEDRLSLILTVPSALMLPAGLLLYGWAADKHVHWIVPMLGTSIMGFGMMGIFMAAQIYLIDAFTRHAASVTAANAVLRSILGAVLPLCGLNLYNKLGLGWGNTLLAGIELLLAPVPWILAVRGAQIRNWKSNRNKETVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIK8</accession>
    <name>A0ABR3ZIK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35310">
        <property type="entry name" value="CELL WALL INTEGRITY/STRESS RESPONSE COMPONENT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35310:SF1">
        <property type="entry name" value="CELL WALL INTEGRITY_STRESS RESPONSE COMPONENT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="576"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="810" mass="87431" checksum="3BAE8E1B6CF24DE5" modified="2025-10-08" version="1">MYAESTTSPSWFDKLASCCGPPSPRLPQQQGRSKLLRRGEKDAAAIWADEPAMTPPPSFGPGPHSRPVDLMQTRNRSISNAVRRTQWPSQEQQLIDINGDATPAGTQHSRNNSRTISRGHSRGGKGQGQTPRSRHGYSRSGSSTLVGGGTPASTAGRSSHSIRRRLRTPSSLSLFPLPPSLSSSSSTRRPQISAPTNFRHLQSGTFVFPALPQEEQQQIQQYQREQYHQLHQQQQEEERQQSQRRQQQVDQEQQQRQFQEQQQAFQQQYLQHYQEQYRQQYQQQFQRRPPSFQPLDFTTHLPSPLLPSFQRATIYDDGDDEEGDIVTMPPRVHTRNGSHGDDDLSINRSVFHDRSHSAMSFHLPRRPVGAGAASVAGSIRSGTTGTNNATKTSVSGATASDVAAPAIPVRSRLRSHSSPAVESMVERIASAMIEMEKLQAEIDSVVERQSIYVSSRPSTAYGSVAAEVAPLKLFPSSFDEMPSVPAIPATAPSFAERLSTERPKTAPPRSSVYFGTATEVNTVPLPSNSTSTLTQQTQPQQQQQQPTAASSSVSVASAASVASAAAKAAKAKARAAHSASGSTGSMRGGGSGGSTGGARINGRPVDVPLAPPLPLVLRPPLRKKKSFSRVSNWLSSHERNEGVDGPNASVGGGRDRGLSLDSVTNAPRPITAKDGFYQCLPPAMETQGSHYGRHGRTSVDSIVSTVDTLSTWTTERDEASRQVNVHDDDNDADNQLEQDYVDELPKHDTPTPTSATTMTTLATLLTAATTATSTPTIPAMATAVASSSLAEKSSASLLGAHRPQSVGVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ20</accession>
    <name>A0ABR3ZJ20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1313"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="606"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="697"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="940"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="979"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1324"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1346"/>
            <end position="1358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1691" mass="182269" checksum="701053696E5CA679" modified="2025-10-08" version="1">MGHRDKWFGLKSVHASGSSVQTSGTKSSSARSRNNSAGTISSSSAPRSQTPLDLDRGLTESPAELRVARKVEVTSAHTVTIYPELDRYRDVDISPATSDGYGPAHPDILFRLATEGFPPPPTPYYSGTNSLTSGMSGSPSTRFSESPGPGPYSRDTTPTSMSSHSPGLISSVRMPSAPRLRQPVRGRTGSFGKDSANGSVTSASIAPTQTLAAIRESLNSSSSSSNGTVRGGDKREKIKKKRMSPVPPSPPPRKSSQNFKKSDDEKERDSPMKQRQRPLRTHTQTSQPTQSARPSQPPASQKSATKSEVPGSSATATSSQRHRTVASPPQTTRQQPTPPARPSRDGTPDLSQLDFTLPVIQSNLAYAPSPDHLEDLHQSASSPPSASAASAPVLEQARFLYDQQHQRRPGSPSHSQQLVRPQDTNIRSPTSRHPAGTTQSQTTESSRPARTVSSSPGPTLSSRADSRQGRVPTQVQVQTQVPGNSSKESVVRPTRTPSPNVSTFRTRLNLFGRRTKTAPPTANSSASALEKKESGTTRKGPTAGTGHEGYGRLGSGRRRSSSVSTFLRGTGSSQESLASSSPQFQDPFLRDRLSPVVIAGGEIVDNQNKNTTGNTTGYELSQTTSNTSASLSVSASGVGGARTNPPAPSSGYYRRPSTDSRADSVSSREDRLSLWPSAIPRGSRQVSPSPVGFGYSNNNNNNNNNNTNRRQGSRRPSDSSDSEAVMKPTLAFRRSVQRLRSPDRAQVRVPRPIVVTQQNGGIPSSMTSADMSIMSDDSVIETRPDTAVSASASRGRKGSVSNNEKPPAMPKKLTKRARSPRKWNLFGRSQSQPATSKKALQSTSTVAVTVEAAAVPVEKKKPVAFYAMIDSSEQEDGDMDVEDILREARIMGSPKMPERFGSRERRPSIEQTVFGSDAPPGLPPGFQPTRARAPPPPSPALSQMSQQQQYQPEPAPSMQEQQQTQQQEEQQRVQREQFHQQQQQQQMRLQLSRSAAGPVVREVPIETPAPSHGANSNAIVPPPPTAARQGRPSRLPQVGRIPKVVSARPEQTSPKSFSRPFNRVSMQLPSSSLGPLLNSLDTASVAKGPSPPKSITPDLMHDGSTVTGSSADPTARRFRLSQNVSADAELIDQGNEFFSLYSRKDSQTTSCTSSSGLFSFADATAVVPDPTAPLVEDEIWDEYNDLLGEDGSKIPQSATSSQGMPFHLEVPPVKEVRTSPSTLVGTAKRLDQRTVAPLESPTIVVNLRPKRSISSAAAAKTGRPPVASSIYSVNSPTRLVDHAADDQRDSQLSQPPPTPFSVTDFVSGYGDRNNSGIATKKLPAVVASQRSSASSQRSAKRRTRVSDSSVYSQVSEDNSPMSQVNLRVGSMTVSKWLTFGHVLFSPARDDMVKAVNPPNGHSVLVIDGLGNDDWSFYAAETYPAATFFNLSPRAPLPVDQKNGASAFPISPLNHHQIQYKSHADKLPFGPELFTTVVLRFPAAAPESHYKNIVNEARRVLKPGGYLELSILDVDLNNMGPRTRRAIRRLKEQAHSHTPDIHMGSAADAILRLLGIRGFTDIKSCRVGIPVASAIPQPNSDMVAADDVKRATTGATKPKKDQRSLAEMINDESPVADENITSMVARVGRWWHSRCYGDAAFEPSQRSAPNTTGSSDMWMDRALLAECEGWGTNLKLMVCYARVPDLKRVASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ56</accession>
    <name>A0ABR3ZJ56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Microtubule integrity protein mal3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BIM1</name>
        <name evidence="8" type="ORF">Sste5346_002386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EB1 C-terminal" evidence="7">
        <location>
            <begin position="87"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="177" mass="19499" checksum="2AA2BACE6C355ACB" modified="2025-10-08" version="1">MGCFQKHQVDHPIPVQALVKCKMQDNLEFLQWTKRYWDQHYPGGDYDAVARRKGAPVASGGGGARAPVSTGAVRRGTTPTTGPRIGKAAGGGPGSAALQQENNTLKETVVGLERERDFYFSKLRDIELLIQQAVEEDPELEKQEDGLVKHIQTILYSTEEGFEIPAEEAGLDDQETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJR5</accession>
    <name>A0ABR3ZJR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF14">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="308"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="998"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="233"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="736"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1209"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="737"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="790"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="933"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1214"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1224"/>
            <end position="1233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1233" mass="133985" checksum="D36F2E413113D165" modified="2025-10-08" version="1">MSRSRSASFSDDDLMIVSSQAMSSQGYGSQDYPSQELGGDLGGDLMSSPLRPIPAPNDVIDITNSPVAPAFTPSKGSGGIGSSAAPTTRQPVFGRPTQMSTPTSSSASSSQHHKPAMSSSAAAAAALVQRRQNALFNANQKRPEHHRPQRLTGPLAPKQPDRKAAPRPVFSSVGSTQEKGGTAYPVSSFYSNTTTNKTIIKQSIPSSMHADVDFYTDPNKATEDLKALLEGGMEDDEDDEEEAPATADPTKDAAKAATATADKEPAKKKDKQETEKYDDGTVEGIKVKLLPHQVEGVKWMRGRELGPVKRGRVPKGGILADDMGLGKTLQSISLILTNPKPTKDMPGWKKHYENITGGTLVVAPLALIRQWEAEIKEKVSRDPPLKVCVHHGPQRTVRPSDLAQFDVVITTYQILVSEHSHSNNTLRSGCFGLQWYRIILDEAHSIKNRNAKMTKACCAMPAEFRWCLTGTPMQNNLDELQSLVNFLRITPYDNLAEWRAHIDAPLKNGRGYLAIRRLHSLLRCFMKRRTKDILKEEGALVPGGKKAMEAAAAAAAAEEKAIKDGTQALTPGGSGTSTPAKVSATPSFKITERNVVSVSAQFSPSEREFYDRLEERADKSLEKMMQGKSMSYANALVLLLRLRQACNHPSLLTFKLEKDKDAMSTDAMPASQKSATTDSDIDALADVFGGLGIQAKKCEVCMTDLTKDEQRECEAAGDGFVCTNCIEDRDILEGKPRVKKGKRSKKHHRKDKKSKKDKSQKHKVKKGTSAAAANDNGDDDDSILPASRKAAQRKPRNRRAIIDSDDEEDDGSWLVGEEERGSLRLGKAGGEEDENAEGGGDWINSDDSIHKSEDEDEDASRMSSFIEDDEKEVTAANKSGKNKKHTKEILRVGGQVWDSGDSGDEDFVSFAKSTGSATGSDDDDTISGSETESGSDSDSGSDEESDADSEENSLISTSELMSNVDDDSFIGRKSAARRRRKAPFGSPDDDATVLVSAKIRKMMSILKKEAGEHKFIVFSQFTSMLNIVSPFLMRAGLGHVRYEGSMRNDAREASLHSLRHDPNVRVLLCSLKCGALGLNLTAATRVIILEPFWNPFVEEQAIDRVHRLTQTVDVTVYKLTVEDTVEQRILALQDKKRLLAAQTLEAGTAGGKGKKEALKLGLKELMDLFKHDARGPPGMQNGGDVDVGQDGVNAAFVDQFAAMGTGLLRRREGGSGSRGGGGASQESAYSRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL02</accession>
    <name>A0ABR3ZL02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit GON7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_001968</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GON7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014849">
        <property type="entry name" value="EKC/KEOPS_Gon7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08738">
        <property type="entry name" value="Gon7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0779">Telomere</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="95" mass="10080" checksum="00FBE62145B40A78" modified="2025-10-08" version="1">MSTPVLKAAYSAPNHESFVTSQELSTAPVTATTTTDKTAYLAALRTAVTAIQENVNKELTARMVIDAQAATDQAAADVAAEAEEQNYGEEVMEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL62</accession>
    <name>A0ABR3ZL62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Scaffold protein Nfu/NifU N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.70">
        <property type="entry name" value="Scaffold protein Nfu/NifU, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014824">
        <property type="entry name" value="Nfu/NifU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036498">
        <property type="entry name" value="Nfu/NifU_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08712">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00932">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110836">
        <property type="entry name" value="Hypothetical protein SAV1430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Scaffold protein Nfu/NifU N-terminal" evidence="3">
        <location>
            <begin position="87"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="35432" checksum="3BAE8EF95C94D993" modified="2025-10-08" version="1">MTKSSLSRVTATAAATAMRPAFCRRAPRVAFASLPVTSSSTSTTSSSSPSARRGYHISSSSRPRLHSATPTQPSWSLAGRGRRSIFIQTENTPNADALKFLPNHQVLPEGIAAPFIEYLSPRATIAPPYPSPLAAQLMNVDGVTAVFYGSDFITVTKAQDANWAHIRPEVFALITEAITSGQQIVRPAAEATASAASGEAGGPPTEVDSLQYDENDSEVVGMIKELLETRIRPAIQEDGGDIEFRGFEDGTVKLKLRGACRTCDSSTVTLKNGIESMLMHYIEEVEAVEQVLDQEEEIALSEFAKFEEKLKTQKGPAVPPSASKSADSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLD3</accession>
    <name>A0ABR3ZLD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MAGE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="151"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="501" mass="55543" checksum="55DFE652E186177E" modified="2025-10-08" version="1">MPTLSQRPRRRPAYEEEEEEERPRHRRRQQQVEEEEEEEEEDGEGDDDEIMVEEGEEGEEEEEEDDDEEEEEEEDEHARQREQRQREKQRRRREAERRQQQQRATQQTQNGDDHGDDDDDDEEDEEEVANGAAAQQMDRQRLHYELLAKKLTRYALASEPRRLPIRRQAVKEQGESPGCVAARSARAQTLLKVSLTTIVLLNEGKHFRKVFPIAQDQLRGVFGMNMVDWPAREKTTMTMRERRKALKSQSNVKSGKSTRADAAGNSTKEAAVDRYLLVSTLPSEYQECVFTPIVSDPDAAEGLGLESAIPPAPDAAYMGFVTLVVAFITLSGGEMANEDLEKLLSIVHNGRSAPARADEDFLQPVAAAMGDHIDDEDGRGAGAGGGGGPSDDGTPTAGGTLQHMVRQGYLVRVVEVTTTGEGRGNVGGRGVPAGAKVTWHVGPRGQVEIGPAQVADIVYHIYGDDANADLERRLRSSLRMAGGAEAGARQGTPARQRTEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE3</accession>
    <name>A0ABR3ZLE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145821" description="DUF7907 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="3">
        <location>
            <begin position="43"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="207" mass="22404" checksum="C7B4310791AD99D1" modified="2025-10-08" version="1">MRFSSSLAVAALATLASARMTPRASRNDGANARSAHPDHENDKPFILQTRVKEGDYPGHNGLYVYAYHTGAGLNDAMLDPQESVGNNGTAFTSDISDRFFVVLYDLAGSPYELEPATGTTPYPDLLPVRINVDGAPPSSSNAFYFAYNTLRWTNNINTMSGFGGWLACKSEHGSLENLSVPGVQLFYRSTPGPTPEDCSDVDLVPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPC2</accession>
    <name>A0ABR3ZPC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001703</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="955"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1077" mass="116545" checksum="7B72DD1353A9A256" modified="2025-10-08" version="1">MEPLPGGVPTVAGRTPIACQNCANAKTGCDKRVPCSRCAEKNLPCAARFARRSSKAAVRAAQASAAAAAAAAAFTAQMVTSPTQPGGPQPLTPTTFIDLEHQQQHHASVIVAGNGGMKLDSPPLRSPLGLEQMVVGGATGLEMCLSDPSTGLAPSHLHHHHHHTPHQQQQQQQQQHLHQHPHLQHAQHQDTTHHFGQPKKSPQHVHNNLSPDNFTSPHAVRGVDGLDEFMGFGGGGNEFMGPETSYQDLIWADYPMDIDMYASPLQLGRQSDMAAAAAAGLIPPFTATTELSDISSSSEPMTVSSSQGSVHTRGTSILSSTGSGEYEGRKNSTASIGHGVGSISDIGGMPSNIHGSGSNLFRQQQQQHLQQQASMFDMAAMAPCIEGGIPEFEVVVASEAAWPLARCTPPIYSGACPRTAIVHLECLEQKSKQEGTWTALEQFLDSHQPDSTDAPQVVPLTSRSRDKMLAITQSFLHKALDIHRSGMYPKNGAASPGAADFNFNFIVLPPSRILEYFLKSYVHSLAIYYPLIVGGVVDPNDMLDNNQASTLLVLLMIAQGAATVPMAEARYLSAGLSETCRISLFDIIEKNVELSADRTALRCALLFTLLGAWSGDKWQMDIAMGQRSMYLSMLKHAGMLEPQPSMVPSLGSPTNTELQWRSWLHRESQNRLVYNWVMVDQELSLFHDTAPVLSISDLQCPLPSSEALWLASTADRWSSIAQSTYNTSTTSNNTASASPLTPSLCELFQDFLHDNLARRKTTLSPQQLRLLLHPLQGLLCHLRQMLSCLPEVPPVRRATNRTVTKASTMQRLEEVQAQLQHWYELSMAYYKANPGCAVTRCNLVLYHLISLNAVTNFPEIERLARRDGLSATADPSLRHKRCIFLREEAVFHCGQVLRVLRQMPADRRPSWWSAALYRAVLILWADSVCHVDRKAGQHACEPAMVAATTTAVGGGSPTMVGSPIKGSPAAHSPGLSPRSHSSHADGANTGGASAASLVAIDSVTPEDQAVIAYLWDGDGVTAVLTHSDGSHFTLDTPSEIVAYGVKRIDEAVSTRISDGIRRKLLSLASNWSGEALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPN9</accession>
    <name>A0ABR3ZPN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PARP catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051838">
        <property type="entry name" value="ARTD_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21328">
        <property type="entry name" value="POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PARP catalytic" evidence="5">
        <location>
            <begin position="1183"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1323" mass="149028" checksum="A9810EC9D45D2153" modified="2025-10-08" version="1">MPIITISKSSALRAAWHKELIASNLSAQLDDGTLLEFPSALLQLTRDYLNRKKLVANSDERNRHIDDLIRDHVQSENGCLEIAILACTLEYSPFTAIAALKSLRGDGQENPSYTRYLRCLIVASSIAPRYVSQPEAQVAQALLQIRLGYADPLQIFRNMIATLSTIPNSQMLPAEYINRLLTFCQIPRSYQLYLHMLQSHCRFASLYRSVSWVSDYLLPQQGQLAREVLEVQIPELRLWASWKPDEGMLQKWEGYNFLPEHLARLRPIFHLEGPDVTRGGNTTFKNAGPICFQTVAVEPHDVSLIQRLHQLLLQAMEIGPEAISLLSHLCIETTATDNSLTFAETIIRIGEASCCDAAITLVNSLTPNASVSARMMTLSSTLPTLQRYPALREVFASRIIDIVVPTMQTAQESYKTHLFGSTNDTLSYKIQAYGRAIKQAPWLSEFVPAEFLEGIDRFPPEDVFQGIMSRLQVPQTQNVEKALKDYLLATLGGTSTAEEIAALKVAVDGEQEFWITHQDVERNRILGIIRNLTYMKDMEFLHACRRQILIEDVVLLRDLLGLIERDSHVSCVDMLRILARRIELPMVVNDVWISLMLLMLQQRAEDLLIWSCDNLTVLDWFRFVTDMRIVFNGRPDQMAALASLGMSLQRLTWWQELQSQYLVGVEYLDRLQRHQNGGIASMKWLYLQEIPNLQALLSTIVGRKTLGYDHRWILSFFESSPNAITTLCNCLAAHDQSSPQGLYGIRTILERFYTVDGWPDSATQAYMLAWRRSKDLTDDDKNALALLGELMGIKPSLNPHGLNIIKNKMLKEYDSVIEQAREVEGLRIQLSRKDSIRTNDLATRIGMQGTRPYIDPDIPESLSDAIECVGTKEYELCFPLTHLQGHDRKVRGIGSDLFPILTVRVTLDGAERTHGFCVHLVPHETVHEPGKGLQVQLKQQPSHTYWRPQSNRFRKPTSRLCTSSFNLFTHALAQRLHRHFLTGNVTLETIYDITNDTIKRPGSQCTACGDELTGLWKPTICTKDGCIKEMSQSGLLVRAYGLLIDAPVLDFLLCCLYSAAKDSSGLQLLSSDCPYDKTRLVTILDSFPALPADETKTPFDLLNKIRSAPYLSHEREQVLAWMSKWFRGCMLSAPQGKRLSIMSDVEQFLLFNSTPECEKAFEDCVNTRGANSSSNLAPARTGDVVFHGSQTSRMWKVLTEGLRNMSNTRYMAHGAVNGPGIYLADEPSTSFGYSGALNNTWSKSAFRNKKVLLGCELIKNDPFAPLPPGTKRPPSGTHIVTDESRVLVRYVFICPNGYNMPPARHIETGMRSTFASLRSGSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPY6</accession>
    <name>A0ABR3ZPY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF16">
        <property type="entry name" value="SER_THR PROTEIN PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G06000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="235" mass="25921" checksum="F133B434D3D42CA4" modified="2025-10-08" version="1" fragment="single">MYTAAIPTPGATRRTRIVCISDTHNSTVKLPKGDVLVHAGDLTNQGSHKELVRAVAWLEKAEFECKIVVAGNHDITLDEAFYAHHGSHFHNQMPQSSDECRALLDSSPTITYLCHESVDIRLKSNKGPHTKFTVFGSPYSPRDGTWAFSYERVNDQASPSLTTINPRPLTGGTLWSEIPNNADIVVTHTPPQSHCDWSSTRGRSMGCTELLGALRRVQPQLAVCGHVHEGWGAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQF8</accession>
    <name>A0ABR3ZQF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="13756" checksum="AA7566C46F00F4D3" modified="2025-10-08" version="1">MAVLTLSRRSKSIIQIKVPPHKRKSHSSPKRRTVVIWKKSADATTTTPTPTATPTPTATPSGDNRSSTLGHHGKMAKTSSSLTDKKMAVPLIRRRIIIVGAWRAIWLASCEKPCQEYLEEPMQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQW6</accession>
    <name>A0ABR3ZQW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cellulase</fullName>
            <ecNumber evidence="3 9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_001599</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3 9"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052288">
        <property type="entry name" value="GH45_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730:SF1">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02015">
        <property type="entry name" value="Glyco_hydro_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01140">
        <property type="entry name" value="GLYCOSYL_HYDROL_F45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577697" description="Cellulase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 45 active site" evidence="11">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="23875" checksum="B26BD2A22BE58E22" modified="2025-10-08" version="1">MLPTQALGALVPAALLLFAQSAGAQSTGTTTRYWDCCKPSCAWTGKGFAQGPVATCDKNDKPLNDNGATKSGCDNGGGAFMCSSQAPWAVNDTVAYGYAAVRISGSTESQWCCACYELTFTSGPVQGKKLVVQATNTGGDLGANHFDLAIPGGGVGIYNACTQQYGAPPNGWGDRYGGIHSASDCDSFPAALKAGCQWRFDWFKGADNPSVTFKPVTCPAELTAKSGCHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQY3</accession>
    <name>A0ABR3ZQY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Opa3 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010754">
        <property type="entry name" value="OPA3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499:SF0">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07047">
        <property type="entry name" value="OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27253" checksum="5661583DE85CD04A" modified="2025-10-08" version="1">MVALPLFKLGALFVRHISKYGANRIKVRAHEHEGFRRFAARYGQHIHQLNMRMSVALLRNSKAEKIAKEKAEAAEAPTAKTKEQVEKETREKAKDEADRAKYGTTAKESHPTTIINPGASVWRRKFRPLPEAKAVDLFADVIGDGFILVIASALVIYEYYRSSSKPDANAERIQELTDQVEALRSAEEEYSRKDRIRESRILAMESALRGFRDPKTKQPLLPPAPTEAESKPETQVATVTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRS0</accession>
    <name>A0ABR3ZRS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein transport protein S9 plasma membrane t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SEC9</name>
        <name evidence="4" type="ORF">Sste5346_000788</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15886">
        <property type="entry name" value="SNARE_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="363"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="498" mass="53726" checksum="1A1DB1F8DC693139" modified="2025-10-08" version="1">MPRFGFSKDDEDGKKASLFSRKKSSANTQDDNPYAQQQADPYAAPMTALQRQQANMGLPVGPKAGRGGLPSGPGPRAGTGGPPPPRGGPSPAQNDNPYASAPGYGGPPANNNSYSGPPPNNPPQQSNGYSAGGYGASGGYGSNKYDNGSSYGSGPPLGRPPTYRSTADSDAGSGGAGGGAARLNARRGGYGGMGGRDDEADDPNRQALFGDAPQRVTEQRQQSSSKYANPANPADGGYGGGGYGAGGGAETDGYGEGRELTAEEQEDEDVKRMNQETRYLRNETDQSLDRSLMIANQSIETARGTMARMYNQRERLLNVESNLDEAANHNKIAEHRAAELKHYNRSMFAVKVNNPFTSKQRAAAQAQAAIDEHRSEREQREETRRLAYLSNRNAEQNFEKLERTTDQNRRLGQTKTGISSKFNLEDDDEEDIEKEQAIERKMDLLSGAVGTLNMTAKAMNEFATEDLDHIDRIAGKSDNVDDQVRANRYRLERIEKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRT9</accession>
    <name>A0ABR3ZRT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hus5</name>
        <name evidence="10" type="ORF">Sste5346_000889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="157" mass="18101" checksum="3BBD40F4D946EA61" modified="2025-10-08" version="1">MSLCQNRLQEERKLWRKDHPFGFYAKPVRNAQGVLDLKVWECGIPGKEKTIWEGGMFKLTMTFPDEYPTKPPKCKFVPPLFHPNVYPSGTICLSILNEDEAWKPAITIKQIALGIQDLLDDPNPDSPAQAEAYNLFKKDKVDYERRVRRTVQENPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY0</accession>
    <name>A0ABR3ZRY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA/RNA-binding protein Alba-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34559" checksum="55D258E2A5A74D77" modified="2025-10-08" version="1">MGPNKRHAAAVPSVQQQNEKKQKTATSAPLSTPKPAKPTAMTAGSSTVVPATPGAAVDPAAKRKQQQSPAKEPRPEKRPKTTQTEKTTSKKQSPNQPAQKQPEPISLPLEPHAAILKELESKYDVRTLSVISSSKMEKRINSVLSHIEGKPADTGAQDGQTTASSASRPGIVLLHCRVADTNKMISIAEIVKQRIREGRFSKETAGADGAAKKKGKKGSKLSKTAWYQYNRIYDVSVPKEAGDAPVSGADEEDDGFAPAVHRLDEALKGKNDSNRQITTYMSIILSRTPVVELQKNLEISVQTSIDPLEVEFEQWVART</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSF3</accession>
    <name>A0ABR3ZSF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="1">
        <location>
            <begin position="321"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="464" mass="49691" checksum="3FF343A5B3FAA9E1" modified="2025-10-08" version="1">MARPILLFCCHPLTGHITPVLRIAAGLHKQHGWRVAFLSSAFFRARIEAAGLQFLPLTSDAEDMDDDSLFDRKVAGVAGIVAEQMAGMPQSVTDSRHQAICSVPGEWVSLQAAVDTLVSENPGERIQIVTEAFYYGSMPFKYGVSLPPAVLPRTVCISITAPAIRSVDLPPFGNPAPFDQTPEGHARLAALWEEWTTTKAVGLTALWQMKMREAGGGAIQPEHVKDLVFMGGGNYVCHDAIAQVGVPSFEFPRSDIPAGFRIVGVVPPVVPAAPPAFAWWEELVANQALPIEERKKVVVVAQGTVETEPTELIVPTIQLLADRDDVITIAILGVKGATLKASIPSNCRVADYLSYDAVLPYATLWVHNGGYGATMHGIAHGVVQVLAGDTQDKPESGKRVQYSGLGIDLATARPTQEALGAALTTVLSEPKYADTAKKMQAEAAALDTFKNVEAMILEQIEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSW2</accession>
    <name>A0ABR3ZSW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="544" mass="61347" checksum="5249C2723C394F12" modified="2025-10-08" version="1">MPTFAGKIRESDVLAGLCQQREEDNSRLFNELSEQRRISQQQLNEIRELHEALRALQDTPREDSKMVAQVLALQEQNRFFESELKEREVLVTRLEESYEERTKALISSSEKFAEDIQQLNTEFHKREEEYRRSVDQASELAIKEARRASDENREETKRDLQQERARRQSLEKELRKAKEDLSVTEEKGRLSEQSNEVLRNELATAKVGNQAVTLHLEEKTRALENHRDRDATFITHLKAALTDKEMDFVNLRNSMEAYDEKVRVLIEHLRVWAQDYTHIGAIRSRLEMLSQIDQSCAATARIREAEQIDNVLAQLRQYYARQNERANKLDFGTGRSPATKESSHHGSDEDQEQRVSDLSAFLDAEVAVNRPAGRTTSAAETWNSAVQAAMVGVGADSLKTPGYGPPEQSSDMKPPPVLKDRAINVALDTKSGLGTLSSPLVSSPVPKRPRRETRSSAANKAALRNPVSPTGTKETRRAKRKRPAATADDGGVGSKLKKGHTETSVYLQGGDQRSLPVILIPDENEPDHDVMASSPPLLIKIEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT89</accession>
    <name>A0ABR3ZT89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Catabolite repression protein creC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000642</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with creB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat creC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051362">
        <property type="entry name" value="WD_repeat_creC_regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107:SF16">
        <property type="entry name" value="AT02583P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="452"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="545"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="70657" checksum="6DBAEC9E8C45AADA" modified="2025-10-08" version="1">MFVLPPPPRYPTQMLYNGAYLSGQMVPMIETNNTLTHPTGPDCQFLVGEGLYVLEEDLLLATPPPHPSEAPVVNPNPLATTPLPATAGTKISMIALVDPPQPPALALLLSGANSASPPADSLGASSTPFATVEEHPDGESSAAAGDSATGRLSFNTNSASSDTAPAGATAPGAPAVPAVDNPLTANNFNNATASATSTLASLAGMGGNKASGGKQRKPKNNVTKSNSSFISRVIVNDNLTKRLQDRPANGIFVFANINRAFQWVDMSSETKKDYFTKILFTKAHCLCHDTNPVTKSSSHIDVIMGFSTGELIWWEPFSQRYMRLNKNGIIRGTPVSDVRWVPGSENLFIAAFMDGSLVVFDKEKEDAAFVFDEDEANRQRLSNSTEARTHIQVERSIHTKGQKSNPFAFWKLSNQRINAFAFSPQANLIAVVSEDGSLRIIDILREELLGLFYSYYGGLTCVCWSPDGKYVVTGGQDDLLSIWRVADQTLVARCQGHHSWVTSVAFDPWRCDDRVYRIGSVGEDSRLCLWDFSVGMLTRPKAATATSNSNIHTATSTGTAVGRSSKPAEATAGGDGSEEDTDGFVMVDESNNGGDERVHPVEPRARTAILPPVCSQVVDKDPLCWLDFTESSIMISSKTGHIRTWKRPTDNAAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZZ47</accession>
    <name>A0ABR3ZZ47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000323</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="621"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="674"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="659"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="660"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="680"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="754" mass="81760" checksum="8A7A801831F133F1" modified="2025-10-08" version="1">MLVAHHNSTQQQHQQQASFNNISNISTNNKNKNNNQDNTSKLGDLDLSQYYRSKFTALSPPRVHDSAHPGNRLSLSPSSTLSSDFLDASAATAAQDPVLVAGFDSDSEFDQDFDFSMLGGNDLMMQSDHWLPATHLAAGRSFGHPNVSHHRESSLSSLGSTSAGPASPFSQSTSNPHIAVNDSVGDSFTNMSYYEDPSFPLVKQQATSGVHDSLYNQGHVPYAPSADSLPMPHGTYGSLLASNRQRAGVTSSHSERGLQPPPDLSMSSNRSQPVSVASSIASNSPATPSLDQADEEARRRNGEKRLGSPPVASTAADDLLFLFDGGSENDYENDECSRFFNDLVAFHAPPKLDRTMTDVYNDELYSPNFAAMPTSAPSANASHLAPTSQEMFAQRLQQINSQHLSAASHQSPVSTGTPRERSPFRHGSPMAPAQNHDFGASPTSNLRFGASQQQQQQQRGFAGQDAAGQVFRSQMARSQGTSTPQTISPKDAVLEYRDPDGEGDGTSYSLFSQGGGQQNFSVDQMNKAVTNLGRSYPAEMNNGVPAGPTYGYMAPQLNQGLQLTQQYPFIAQHHANSPMASSMSAHHSPAPVRSVSSLAALSEPVPGSQRPGIVNNDGGTYTCTYHGCTQRFETPALLQKHKREGHRQANALAGTRRVDTNTPQGLMNTQAGPHRCERINPSTGKPCNTVFSRPYDLTRHEDTIHNGRKQKVRCNLCTEEKTFSRADALTRHFRVCHPEVEFTGKHRKRGVHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGN3</accession>
    <name>A0ABR3YGN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000128">
        <property type="protein sequence ID" value="KAL1887313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="17"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="362" mass="38955" checksum="96AF417FBB1E1CB9" modified="2025-10-08" version="1">MSSIPTETKGFQVDGPGTPPEFHLRSFKLKVADDYDVDIKIEACGVCGSDVHTVTGGWGKQNFPLCVGHEIVGRAIRVGSKVTLVKVGQRVGVGAQVYSCGECKQCKEENETYCQVNLINTYGSPWPGTDIISQGGHAAYIRTNEYWVFPIPESLPTAAVAPMLCAGLTAYSPLVRHGALKKGAKVGVVGIGGIGHFGILFAKALGAEVWAISRSRSKEADARSLGADGFLATNEEGWAAPHRCTFDLIVNCANSIDNFDLAAYLSLMDVHGRWISVGMPEEAGQVVRAQDLASNGVLIGASHLGSRREMLDMLQLAADKKIEPLVEEIQLGEVGLKEVISRLKKGDVRYRFTLTGYDKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH76</accession>
    <name>A0ABR3YH76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010074</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000112">
        <property type="protein sequence ID" value="KAL1887679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="590" mass="66289" checksum="8281106BF53A061A" modified="2025-10-08" version="1">MSPFINNGHSKPTIPLVASPDAPTLFNWNNTDEHGYQINEQLMGTKRHMKIVILGAGASGINFLKLVQDQLEDVELVCLEKNLEVGGTWFENTYPGVACDIPSVSYQFTWEPHIWPEYYSSGAEIQKYLCGIVDKYQLMQYIRLGHIITGAEWIEEDGKWHISAKGPDGKLVEETCDIFVNGGGVLNKFRYPNIQGLQSFKGKLMHTARWDNEYDLTGKKVAVIGAGSSAAQVVPNILAQVKELHNFIKSPTWITAGFAQRFAGPDGGNFAYSDKQKKLLSKDSESYLEYRKMIESEIGQRFRFLMNDGPEASEARKHSEAEMRRKLKDNEAVADAIIPKNFNVGCRRPTPGEGYLEALVDPKTTVHTKQMQRITEYGFVAHGGTAHDVDVIVCATGFDTSWIPRFPVMVNGIDLRDTWAKGPLTYLGVGVPDVPNYFLSVGPYAPLAVGSLLPVIEVYANYIISAVTKMQCEGVKSLTPKKKTVQAFKAHHDLYVNRTAWSGPCSSWFKRGDPNGSLTMYPGSRVHFFELLKSPRYEDFDFEYLSSNQWAFLGNGFHMREFDGRDTTYWLGLLGGQDRQPQFNEEILRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI17</accession>
    <name>A0ABR3YI17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alginate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010234</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000121">
        <property type="protein sequence ID" value="KAL1887411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047523036" description="Alginate lyase domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase" evidence="4">
        <location>
            <begin position="59"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="456" mass="48418" checksum="B238B20581C50E65" modified="2025-10-08" version="1">MRLTLLFAGAAATAFVHPGLLVSSSDLSRASRHIAAGDNPWAASWADLISITYSQPNYVSQAVHELDRDTDGQYLWQDAAAAFNLALRWKIEGNATYAAASARILTSWAKTLTALIGGDDAYLSAGLQGYELANAAELLRDFTPFADSDDFTSVKKMLEDIFLASNIFFLDHLDGSEHNVLHFYANWELAQVASVMAIGVLTENQTTWDFGVNYFKNGSGNGCVNNAVYAIVEEPGTTNGTLLGQGQEAGRDQGHSAMDVQLLAAIGKQAWTQGVDLYGYNNSRILLGTEYFARYNLGYDVPFVPYDNGIVSQTVISSASRGAIRPTWELLYSHYVQIKGASAPWTSQYLKTSLTFFGGAFEGGAGSWGEGSGHYDGLGWGSLLYHMDAEDLAVVLASNGTASATATVSAVDASVSAGSVSTGAAAANNNTSFASLATTVIVRLTTTVCPCATASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIE9</accession>
    <name>A0ABR3YIE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000114">
        <property type="protein sequence ID" value="KAL1887617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="59259" checksum="DC658B171394558A" modified="2025-10-08" version="1">MSSVPLSSTSGLAHSQFIQLLGAALPYLPALLVGAWALSCFYSIFLHPLRNIPGPFLAKFTEAWRTYKYARGKWHEDVLTLHRKYGRVVRVSPNEVSIVDKEGIRRVFGHGTGTKKTTWYNTWQVPGIGASFFHSTEPAEHSFLRKRVSAAFSMSTVLSLEPEIQEVQDAVWAQLDDAARSGRQVDMHEWASYFAFDVVGKLALGAPIGFVKQATDVMDIIKSIHIGFYQMANMGYIPGQMFWINNHISKFILSLFATDFGKFHKWNSDQLAKRLAEPAEEKATRKRDMLDHFISMKEPDGSPATQGSILIEGGNIIGAGADTTSIGIRTVLAQLVLHPEDYLHVQQEVDHAYAQRPAEGTGRGLQYLATEKLPYLTACVKEALRLHPSILWQLPREAPAEGIDIAGHYIAPSATISMSPLAQNRDRGVFGASADEWRPARWIPGQGSTDSEIKEMDKYNVTFGYGPRVCVGKNLATVEIHKFIADFVHRYNACFINPYRPYVVKSQWFSYQADMFLKLELRDTVSKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YII5</accession>
    <name>A0ABR3YII5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 11">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 11">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tmk1</name>
        <name evidence="13" type="ORF">Sste5346_010086</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 11"/>
    <dbReference type="EMBL" id="JAWCUI010000113">
        <property type="protein sequence ID" value="KAL1887638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="355" mass="41195" checksum="C5E9254B875CDD63" modified="2025-10-08" version="1">MSRSNPPNPAGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRSYETFNEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKVQFKTLFPKTSDLALDLLEKLLAFNPVKRITVEEALKHPYLEPYHDPDDEPTAPPIPEEFFDFDKHKDNLSKEQLKQLIYQEIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJR8</accession>
    <name>A0ABR3YJR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="319" mass="35321" checksum="17E8F0998710FA25" modified="2025-10-08" version="1">MAPLIPRMHVFEIDDQPWFPAWCRGRIQAALTRAWIMKVPILQSASPASLVADVLRREVLEKDGQQQSSSTSPWIMIDFCAGGGGPTPSIEHILNSSQKDPNAAPTQFVLTDLHPHVDDWAVAAANSQHVRYAAQPVDASAADPKAILNEAFGATSPTKSSQNAVSDNARVCRLFSLAFHHFDDPLARDILKNTVETSDGFGIFELQDRSFSAFVTTLVFGLGILLTAPYYAWRWRSPMTLVFTYLIPILPFVLVFDGWMSMLRTRTPDEVEALLRTCGASTADTDAWELRSGEVRHLWPCGYMKWIVCTKKGAASKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK33</accession>
    <name>A0ABR3YK33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alternative oxidase, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AOX1</name>
        <name evidence="5" type="ORF">Sste5346_009968</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.13" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047639">
        <property type="term" value="F:alcohol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF119">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="667" mass="73948" checksum="A030F5C1A171DF46" modified="2025-10-08" version="1">MSLPDEYDIIVCGGGSCGCVVAGRLANLDHNLKVLLIEAGESNLNNPWVFRPGIYPRNMKLDSKTASFYESRPSKFLAGRKAVVPCANILGGGSSINFMMYTRASASDYDDFQAKGWTTKELIPLMKKHETYQRASHNRDLHGFEGPIKVSFGNHTYPIKDDFLRASESQGIPTVDDLQDLTTGHGAEHWLKWINRDTGRRSDSAHAYIHATRAVHSNLYLAVNTKVDKVIIDETGRAVGVQTVPTKSVNPAGVQPRIFRARKQIVVSGGTLSSPLILQRSGIGDPAKLKAVGVEPKVDLPGVGLNFQDHYLTFSVFRAKPDVDTFDDFVRGDPEIQKRVFDEWNLKGTGPLATNGIDAGVKIRPTPEELKQMEAWPTPHFKDGWESYFKNKPDKPVMHYSVISGWFGDHMLMPPGKFFTMFHFLEYPFSRGSTHITSKDPYAVPDFDCGFMNDERDMAPMVWGYIKSRETARRMDAYAGEVEGMHPFFEYDSPARAHDLDLATTKQYALPGNLTAGIGHGSWSSPLAPADKLPNASTLSSNRVEHRDDLPYSSKDIEAVEEWVKRHVESTWHSLGTCSMAPREGNSIVKHGVLDERLNVHGVKGLKVADLSICPDNVGCNTYSTALLIGEKAAMLVAEDLGYSGASLEMKVPTYYAPGESRLTYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK58</accession>
    <name>A0ABR3YK58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BAR adaptor protein Hob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hob1</name>
        <name evidence="7" type="ORF">Sste5346_009406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="6">
        <location>
            <begin position="17"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="397"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="457" mass="51180" checksum="5D634F638EC49D2B" modified="2025-10-08" version="1">MSFKGFSKGIARAPQQFRQKFNMGEQTKDPIYLDAERRFDDLEAQTKKLHEESKRYADAINGMLTHQIEFSKAIAEIYKPISGSVSDPDSFIAEGNVEGIRACEEYEAVVHDLQETLKPELEMIESRVVQPADELLVVIQAIRKCAVKREHKKLDYDRHRAALKKLQDKKEKNLKDEKAMYKAEADLEQSTQDFDYFNDLLKDELPKLFSLERQFIQPLFQSFYYMQLNVFYTLHEKMQQIDIGYFNLTLDVQEAFDMKRGDIQERAEKLSIVKFKTTGGRRPGQPPKSKYGNRLTIEGRKDRPLAITQGTGSGSGYDSASPPGSPATGASATYPYRNRANSSAEHPPPPYSAEVDSSNSMTKYGSHVGSSASALAAAAKSKPPPPKPKPHRLSATPAAETATALYDYAAAQDGDLSFSAGDVIEIITRSDNVNEWWTGKLHGRQGQFPGNYVQVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK82</accession>
    <name>A0ABR3YK82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">homocitrate synthase</fullName>
            <ecNumber evidence="5">2.3.3.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">LYS21</name>
        <name evidence="16" type="ORF">Sste5346_009951</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58884"/>
            <dbReference type="EC" id="2.3.3.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:12930"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.14" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004410">
        <property type="term" value="F:homocitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07948">
        <property type="entry name" value="DRE_TIM_HCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02222">
        <property type="entry name" value="Homocitr_synth_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048253">
        <property type="entry name" value="DRE_TIM_HCS_fun_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011872">
        <property type="entry name" value="Homocitrate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02146">
        <property type="entry name" value="LysS_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="40"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1887839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="47490" checksum="D6DF006B3D3ABAF6" modified="2025-10-08" version="1">MSPSADVSSSSLPADQQAHTTRNSNPYKPVGDFLSNVSRFKLIESTLREGEQFANAFFDTETKIKIAKALDDFGVDYIELTSPAASEQSRQDCEAICKLGLKAKILTHVRCTMEDAKIAVETGVDGLDVVIGTSHMLREFSHGKDMEYITKSAIEVINFVKSKGLEVRFSSEDSFRSDLVDLLALYRTVDKVGVNRVGIADTVGCATPRQVYDLVRTLRGVVSCDIEVHMHNDTGCAISNAFCALEAGATHVDVSVLGIGERNGITPLGGLMARMIVSDREYVTKKYKLHKLKEIEDMVAEAVQVNTPFNNYITGFCAFTHKAGIHAKAILNNPSTYEIIDPADFGMTRYVHFASRLTGWNAVKTRVGQLGLSMSDDQVKLVTSKIKALADVRPIAIDDADSIIRSFHLSLTGEDSNGAAAESNGAAPAEAAPEVSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKF7</accession>
    <name>A0ABR3YKF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyruvate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009658</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006203">
        <property type="entry name" value="PRK08327.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF164">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="6">
        <location>
            <begin position="140"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="4">
        <location>
            <begin position="343"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="5">
        <location>
            <begin position="544"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="76379" checksum="93EE3E0843D1DE13" modified="2025-10-08" version="1">MPLPAPPPLLSFPPCRAARMGRAASATSARRWLATSGSTLPGARLHRARSSPSCRGGQSFAVAATTTVPGAARFIAYTSSNTNNLGTSKKITSNAKSTSANFAAKPILPSQAFSTANQTRAASTSTNSSSNFPDPNMYTTSFAFFEALWEAGVTHCFVNLGSDHPSIIEAMVQGQREKKDKFPKMITCPNEMVAMSMADGYARLTGKPQCVIVHVDVGTQGLGAAVHNSSTGRAPVLVFAGISPFTIEGEMRGSRTEYIHWIQDVPDQKAILAQYCRYSAELKTGRNVKQMVNRALTFAKSQPAGPVYLCGAREVMEEEIKPYHLKQDEWKPVQLGGLPPDSVQDIATALAGAKEPLLITGYGGRNHGFAPSVVELANAVPNLRVLDTGGSDMCFPADHPAWLGLRFGSHDAIRTADVIVVVDCDVPWINTQCPPKEDARVFHIDCDPLKKMMPVFYIAAEQRFQADSLLSVQQLNEHFKANPVPAASGKDSARVEAHKALLAKIDKAAEPQADGGFGVGHLTKKLRETCPSDTIWAIEAVTSTGFVHENLQPTQPGHWINCGGGGLGWSGGGALGIKLATDYEAGGKNKGKFVCQIVGDGTFLFAVPGSVYWISKRYNIPVLTIVLNNKGWNAPRRSLLLVHPDGLGSQASNEEINIEFSPSPDYGGIAKAAAAGDLFTARVDQSAELEEVLKKAIASVQSGTSAVVDCKVAMGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKS4</accession>
    <name>A0ABR3YKS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD dependent oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="53435" checksum="B5D58408EA7C0331" modified="2025-10-08" version="1">MPDLNSVPPSPRVLAASRQSSSASIAGIAAASNNNNNNNNNPPPPSTTSATSTTTQMPPPPVPTSPSSIHVFPSNQQAVTQGTNIHPSSMPSPFLPPPLSLAGGGGAVGGAGGGLVPPGDGPGVGPGPGPLRHPRPLTAAELHMQLEKEQEAVVNRLTRELTLLRAQNASVVSNASSTSASGLSDAAATAGGPPSAPSGSVSGGGPTDHSLFSGTSGFSIPSSTGRHSRAYSNTSTRSQTAGGGAGNAPSVVGITAPAPIRPQAPQLSRQNSTASRRSRANSPGPLSSPYTHPSHIAEAAATGTGYFQQGQQQQQQRPGAATPSASEMSPALIPGTARYEETVFYRAELENVKRENEALRRRIRELEQAAAASSAPGSEQAQPPSSHHHHSHRGGAQRERRERRSSDASRGRSESVSTTASMNVQSPGSVPAVSSSASLSALAGSNLPTPSSASTAGSTIATSQSMTAGGGASGGGGVGIAGRRESGRERVTSMLSVAGSVAGSVGVGVPEDEVRVGESAASAGLRGQESSSGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKU4</accession>
    <name>A0ABR3YKU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sequence orphan</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038781">
        <property type="entry name" value="C365.16-ike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845:SF1">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="43378" checksum="FF50759AF5FF148B" modified="2025-10-08" version="1">MAPTATAPVLAPAVSIDRSPTSLPEPISTPSPAVSSTSSTSSEASFSSSSGSDSLRQPSSSSPSTTTSSSSSLPPSSNPTPSRPQLPTPSLPHASIPPSPFSKRASADSSSFTTTSTTASLTTATSTAASTANLQYNTKHLGLRLAADAVSGFTAASIVAPLIAIIDRSIMENASGANTLAGSLRSSFATLFRHPQQILLGKPFALICLLYGGTYFTANAVDTAASTAHNRPASHVTAGAAKFAASSATNIGVCIYKDQVFVRMFGPPGVVPRPVPLPSYLLFALRDCMTIFASFNIPPRLGPFLNEKFGLGDCSGATKNAFLKAVSGQTMAQFAAPALTQFLSTPVHLLGLDLYNRAWQASGQAGTAGNPATWADRFAAVRKNWLVSSVARIGRIVPAFGVGGVVNMKMRKSFMTRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL69</accession>
    <name>A0ABR3YL69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ubc15</name>
        <name evidence="10" type="ORF">Sste5346_009492</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23795">
        <property type="entry name" value="UBCc_UBE2G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="6"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="175" mass="19768" checksum="3A5DA9D76C44A2EC" modified="2025-10-08" version="1">MASSSGAANLLRRQLKQMQTDKDIPGISCGLVDDNNIFQWMVMLMISDDVKYYGGGNFRAIMTFPPEYPLLPPTLTFQDPKPFHPNVYPNGDLCISILHPPEEDKYGYEAASERWSPVQTPETILLSVISLLASPNDESPADIEAARLWREEQAGVHKDFRKRVRQCVRESLGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL85</accession>
    <name>A0ABR3YL85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="51"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="729"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="866" mass="94640" checksum="B84641DF85C46495" modified="2025-10-08" version="1">MSAGRMTPESQNGRSHHHNHHGHHGHHHTPNNHHGAAGGSRRPQQDWAQINDWEMHRDRITELYRDQGLHLKQVQKIMAEQHQFYASQRMYKTRISKWAIDKNLKAADVATLLRLQQQRAALGKKSKFTIRGRDIDFARVDQYLKRDPTLLKRSQHGEDPTGDILPSHMEAAGITCRTPSPTPPPSPSPPAQHYRQQHHHHDPYYSGHGQHQLHHPYHQQHHHNPYGQHHNHFATTVPIVPSHTPIPMVTTASTFPTLTPMSSAPFTTTQGSTIPSISLPTAALPYIPLHTAHSVSSFDHHQRTLPSQHAAYDARRNSIANPQTLLSSVPQSSMPSASNISNVNNVSNVSPYISSSFPPHPQTPVLFASASPINESSIQDDLTRLTREYVNQALHQGMWVQSGNSMFVSTKANDGSGAEASTRLAAWGQELRAGRQLIADGILDDGFRSVNRTMDNLRQHLQDEDPSLLFYLLYSTAFGTRCPLDRLSRGRDSTAELRQISVALGRQVRSLTHIVLGEQHPIARMMRHLLANDGRLRSPSHMAALAAPVAAMRDILAEHNPVGVDRSAAAQCQRLAFLLRLDRNNATEASDKEREDLTERLQGAPNLHTKMQFYTTYMEFLSDLVTQQDKEQRNKAAAEADTSAVHAWSGGSDMDPGVAVSAAGLSTLTPAYSSASDCGATPESTYTTATATVTADNVYQHGKPTLTPVLTGLHGHGQTHGHTPVSNMHSPLSNHGSSGSSPGSSPSQHSLPMADVSSAMIPPPPTTMTTPRTILSGGQHHHSQQHGHSPYTLQPSAYPPVPTTFHHHGGQAGTGMTLASGHQATLAAHNLAGQHHGSSAQMAANSMHDPGSMTWELGDAADVNWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLL0</accession>
    <name>A0ABR3YLL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="55870" checksum="76F873288057DD34" modified="2025-10-08" version="1">MSAKDINAPAHVEVESTPGIEKRLDAGGDDGLAFVLENGRDAWTEEEEKRVLRKIDFTVLPLMFVAALFLYADAQVFGTAAIFGMVQDLGLYTLSLVNGAVVLDLSRYSMASGIYYLGAVAGTYPLLLLAQRLPVGKFLGGFMLFIGTLAILTITCHNYAGILVLRFIFGFQSILTPLCIIITAMWWKTSEQPLRAGVWSAGAAIGNLCGQAIDLGAVHIGGVYAASPWKWLYVVLGSIALGLGAVVFAVFPAGPTTCWFLNDRERMIAVNRLLANNTGIHTKKVKREQILEVFKDPQTYCLSIFNFVFSFANSSLGSFGGLLATSFGYTATQALTLLMPASAVAIVSITISGIAINRFQNRRVLIAILFILPSIAGNALLWKASRTNKGALLAGLYMSAIFYGVLPATSALAAGNIAGHTKKTTLNSVTAIFAACGSFAGPWAYKGSEEARGYPTAQTVLMSLFAVCALTMGFLEFCYRRRNKIKAAKLAQLPAAARDPLMGFRDMTDLENPLFVYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMD7</accession>
    <name>A0ABR3YMD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1888997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039870">
        <property type="entry name" value="Coa4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="3">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="81" mass="9471" checksum="F7FD3498CDD246B8" modified="2025-10-08" version="1">MTKDESKAEASAAAQDDDEPDEWEQRIFSTGCADENAKLTDCYYEKKDWRACKDEMEKFRACWKAHNNDERTSTKDVEPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMX8</accession>
    <name>A0ABR3YMX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="72"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="58357" checksum="E72EA29E4B8FA11B" modified="2025-10-08" version="1">MADRESRQYAVAYDELFNEDNDNEYEAWLDVVLKPASIEYLERFVADKLGGDRGPVYYVNMARGSYNLVLQFRINDNRAPARLALRMPQRGFTVEALTAERLENEVYWMQYIEEQSTVPVPHIYSWAARGDAVDDHIGPYMLMDYVEGQKLHTCLAAWEASDDQADAVEKRKVVFEQLADFLLQLRSHRFDKIGSITRVDGGTWAVTRRPLTIDMHAQLASMPGFSTDGWPRGPLPYAKDYVSLATALRNHQMLCLRNINIPGAWNKKGFFDFQEGEAIDMERALKTARGRFLARHAMALPAAAAHLDESDGNDVDEHDKKPFVLFNPDLSASNILVDLNTARITALIDFEYTNAVPAALADDPPVWLSPKNFMRFLTLGFVAEWQILYKPTLDAFLAVLERVEQKQKQKQQQQQLPPYASELPPLSARMRASWEKRTFLVNYAIQRSELADTIYHDQPTLFPAVPEAVDGTDDWTQEVHTYEEYTRWQIDLYEADRKARHQKRQLGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMY8</accession>
    <name>A0ABR3YMY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Carnitine O-acetyltransferase yat1</fullName>
            <ecNumber evidence="9">2.3.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YAT1</name>
        <name evidence="9" type="ORF">Sste5346_009039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.7" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.20">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042572">
        <property type="entry name" value="Carn_acyl_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="8">
        <location>
            <begin position="100"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="621"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="649"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="872" mass="96682" checksum="F2F8429678BB45F5" modified="2025-10-08" version="1">MPTQVRTFTLPKPLGETLSAFPPVADIPTPTERPASIPRSVPADLDVNPRLNGGGGGGSTLPRIKPSSKPSSMAGYVYDQQPSTNGGGITFAHQDKLPKLPIPELEKTCQKYLSVLRPLQTSREHAETRHAVDEFLRNEGPELQEKLKSYAEGRTSYIEQFWYDSYLNFDNPVVLNLNPFFLLEDDPTPARNNQVTRAASLIVSALMFVRAVRKEELPPDTVRGTPLDMYQYSRLFGTARVPTDNGCQIEQDPDSKHIVVMCHGQFYWFDVLDENSDLIMTERDLAINLQTVVDDATQTPIQEAAKGALGVLSTENRKVWSGLRDVLTREEGSNNADCLGIVDSALFVVCLDYTEPSSDAALCQNMLCGTSEIEKGVQIGTCTNRWYDKLQIIVCKNGSAGINFEHTGVDGHTVLRFASDVYTDTILRFARSINGQAPSLWKSASPDPSKRDPESFGDVDATPHKLEWDMIPELSIAVRFAESRLADLIGQNEFECLDFGAYGKNFMTSMGFSPDAFVQMAFQAAYYGLYGRVECTYEPAMTKVFLHGRTEAIRSVSEESVNFVQTFWADNQAEHKVEALRRACQRHTNTTRDCAKAEGCDRHLYALYSLWQRLTDDELSSTTTGMDSNGYGSPYGSDRAFSPPPRVSSPGTDGDNSTMRARGDSSSSRHNSQQHMPSIFMDAGWDRLNNTILSTSNCGNPALSQFGFGPVSADGFGIGYIIKDDGISICVSSKHRQTKRFIDTLESYLLEIRRILRITSRRSGSQSKQQSRAREIDHMRPRPANRIKSRGRLITGGEMIKTTKAGGSESPTTDSVTMSEDDELGGYGFFDAGMLLQALKARNESLDAGEPKPSELASRRRNIGKKLRLLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPW8</accession>
    <name>A0ABR3YPW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">COPI-coated vesicle protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013714">
        <property type="entry name" value="Golgi_TVP15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08507">
        <property type="entry name" value="COPI_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14153" checksum="CD44E5D7AEEF25EF" modified="2025-10-08" version="1">MDLSNIFRIVNLGVGVIMVLGGISQFFPISFQSVVIGIYVILFGLATALLEFQIPPQVSRYASFLFSFIGRGIFYVFIGSILLHDHTLRIIAGSIVGIIGLAYCVLEFVPSIEPPANMREADAGWGAEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRJ6</accession>
    <name>A0ABR3YRJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyl hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="2">
        <location>
            <begin position="23"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="1">
        <location>
            <begin position="308"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="78428" checksum="AF55ECF86CB83349" modified="2025-10-08" version="1" fragment="single">MAAPTQSRTSGSSMRENAGGYLPIENYGIIGNMHTCALVGMDGSVDFMCWPDFDSPSVFGRLLDKNKGGHFSVSPPVHMVCTTKQQYLPSSNILLTRYIHEEGVVDLVDFFPRPKETAIVSRAPSQGSVRAVRSVQEELKKWLVRRVECIRGKMELEIELFPAFDYARAPHETTIEQTTNGPDKLSKTATFHSADVQLQLDVVVESGETTDTSAVDINTITNPSSTTCTKGPPTVTFRKETRPGMLGPGVVARICLEEGQAVSLVLRKDSPNHITPHITPAVLDAQQHDTQRFWFNWINKSKFKGKWREVVDRSLMVLKLLTYEPTGAIIASPTFSIPEDIGGVRNWDYRYSWVRDSSFTIYILLRLGFKEEADAYMEFISERILTSRNADGGLPIMFTIRGETDIPEFELDHLEGYKGSKPVRVGNAAAFHLQFDIYGELMDAIYLSNKYGKPVTWDQWVSVRQLLDYALTIRHDPDMSIWEVRNYKQHFTYSQVMLWVAFDRGLRLAEKRNLPCPNRAKWLEARDSLYEEIMEKGYNTELKSFIQSYENNTALDSSILIAPLVFFISPCDPRFLNTLDRILLPPDRGGLTSTGLVSRYDTTLSDDGVGGREGAFSMCTFWLVEAMCRASVYEQRYLAGAVNVFENMLSFGNHVNMFSEEISPSGEQLGNTPQAFSHLALISAAFNLDRVTESRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS56</accession>
    <name>A0ABR3YS56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF1">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="597" mass="65245" checksum="4CD4EA7A016E7509" modified="2025-10-08" version="1">MAAFSTSFRRRQAQASTSTSTSTATATGDIRPRLGESVLPSQTSSQRHPRRGPLPSLQTSPQPPTPKSQSSSTSSTSFFGSQLGGQSVINYSYTDLPWKLLAYDIYHSFRLAWALPYIVWPVTPADSGPLAELSPTLANVWCIAVHAVLAVLQLVFLVGLFPAACLLPVWAAAGLVLACLGVNQLLCTVFLNGIGGQIEYHSRPECAPVLPEHAHEQWVFLNGVAVGQHWMQNNLDRLALTFKRPILGIHNKTSGILFDVIECLIQRNYTYATRDVRVCYSILKEKLYRHDITKVVFILHSQGGIEGGLVLDWLLQELPQDLLAKLEVYTFGNAANHFNNPHRTVDAQNREVAAFGPTYAEPETARHKPSSSSTTDNNTPVIPVTTHRTPFLVAESSATRPAALTGQAIGHIEHYAHTSDFVALWGVLHFVSSVPKTRSMPRFLGRVFARNSPRGGHQFCQHYLDGMFPLARHPTTNAVIGCAETGNEFMESEVEVGRDGDESAVVHEAFERSWLAALGNGDSVDVNGVNGTNGTNGVSGENAPSLVEIHANSPILARQASHPRAVKVKDVSRLWLYRNGKSPDDGFTRGLSRFSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS96</accession>
    <name>A0ABR3YS96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="61596" checksum="8316F27759DF7E26" modified="2025-10-08" version="1">MSLISPAPWPRERDLGQDYGPDLGQGPISRSTTVWPRNARRTKSCTECQRRKQKTVDLHQYNTAATSVVPSPWLLAGPLDAMIGLPIVVNKQNAMLIHTFGEVLYHLKGSFDGVPDHDNPFLSHYVPWCVQSPLLVQTSLYISAQPLAERHFLDETTTMRIKVNAIHTLNEYLRSTDAATCAGDEAMGAVAQFISIEFYYGTPQAMQAHLQGLRQMVQMRGGFADTQVGALVTKVALVGDAIIAIAMEAEPILQKVTDSFTYVYDELPPPTFNLSYSSPLLAPRLPFGFCVSALGLHPATAWLLDEMVFLINAVLDLPVTPSEDELASLRSTAAWILERIEQLPVDSPDAVVPATSAAGSTINRGTEETTASTDSQRASPTDKEPPKPHSLLPRYPKFSSDRPLPPVSSSPTQDESEASTTTSSRQPLASQHPPAAPLYTAVRLTASLYTRAILERRPLSEVCTDEDALAILAASWRVPLDRWRGVVGVFLFIMVAIVPTLHQRSDAAGGGGIYSHIHTRFAKSILQIGLMNVALVDWPACREMMSRALRLQRWLRGGEVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU06</accession>
    <name>A0ABR3YU06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rta1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007488</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF7">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33602" checksum="47BE54EC24F0358F" modified="2025-10-08" version="1">MSGLPDGLIAYGSDANCTLAICPVEWSILQYQPSIPASAVFIALFAIALVIHAYEGIRWRHTLGGFAIPMILGCIDEIIGYIGRIIMHGNPFSFNGFLIQIICITTAPVFICAAIYVTLTRTITFLDGSLARFNPKFFIWFFIPCDIISLVFQAAGGALSSTSSGGDRLGVNMSLFGLSFQVFTLIIFILFSLDYLFRYYRRNNGFGTHLANPGRFRIFLVGLWAAILFILIRCIYRIDELSEGYSGALFHNEGVFYGLESVMIILAVFCLIIGQPGFGLQGTSQEIYNAPGTEMNSVNGSKPPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV26</accession>
    <name>A0ABR3YV26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="65"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="305" mass="34502" checksum="A3ECED202CDD1878" modified="2025-10-08" version="1">MATGLDAMLHRRRPGAWQLFLRQPCIYLARLLLSWRPVTPLQPLAKDDALSIVCISDTHNSQPQLPDGDVLIHAGDLTQSGTFSELEATLAWLRRQPHSVKIVVAGNHELLLDANQRGRRPEDERLYSALDWGDIVYLENEETTITCPRNGRQLRVYGSPLSPRHGNWAFQYPPAHDAWSHQHPPISPGIDILITHAPPKAHLDLELGCVHLLRTLWRVRPKLHVFGHVHEGAGTEWVQFTALQVAYEQTVVDKGGLFNLGWVLFYFLQDYFWPAPTTNKCLLVNAAMVGGLRDDEIRRPVQAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV32</accession>
    <name>A0ABR3YV32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hmg-i/hmg-y, DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="39726" checksum="59C0EE3039A519D3" modified="2025-10-08" version="1">MGLPPLSAIATVDHTSTAIPSSSGGNIASIGSSSATEYRDARIKDPIPKKLKGHTGNLSGNFGIMQMDLGGHESPLERDELAKRASESTELAAMRAYQSGHGVSSTKRFVRVPDDPSSWDTYYTTSTTAQTSGQPPSPIAASQPLTPADIKNEQTRLLTLLRGLSPASVVDQICKALSYFGGTPGAAPPPDGVFPRSELSNGSGGAFVGWIAEIFPRLANETSSTAKSLQHSQLAGMSTPAPDSSTEAGAHRETVLLAGAKPNAGPTPSTEASRNVRPEAATDAPAPSTEKRRRGRPKGSKATKARRDKGIKKGPVKNRKALAAAAAASATSKAPSTTQNPRSNLQSSSDANGGPGEDSWVDVDDDNILDVSAATHNLAQNWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV51</accession>
    <name>A0ABR3YV51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="7">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007157</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF12">
        <property type="entry name" value="EXO-POLYGALACTURONASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046424832" description="galacturonan 1,4-alpha-galacturonidase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="386" mass="41004" checksum="CE4A8A65877828EB" modified="2025-10-08" version="1">MIPVLLSAVLTGTMLPLGVVAWDLSPVSMVQPRSPASDGRRCVVTPTQQQQQQPNSNATLVGAVDDVPQILQAFVDCNNGGTVVFPEGARYLIASRLNPVVKDVTVDWHGVWENHQAGFVLSGERIRINGHGTGGIDGSGDSWYEAEQGSTQAGRPMPFVLWNSPLWSINVMNGSNLWFDDIYVNSTATTAPPGKNWVQNTDGFDTTDARNVALTNFVYQGNGVAIGSLGQYPDEDASVANVVVRDVRLIARNNDMHNSAYIKTWVGETISQPHGSYESAGKPNGGGRGSVTNVIFANFHLDDAGSGPAIDQDSGNNAFINFTGTLNGKNSRPGGDSSNGNSSINNNTSSIRTARISCSTRAQGECKYTAPGGVHGMIVLNDLVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV71</accession>
    <name>A0ABR3YV71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endocytosis regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LDB19</name>
        <name evidence="3" type="ORF">Sste5346_007294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024391">
        <property type="entry name" value="LDB19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF76">
        <property type="entry name" value="PROTEIN LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13002">
        <property type="entry name" value="LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LDB19 N-terminal" evidence="2">
        <location>
            <begin position="194"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="58112" checksum="5ED9ED231AD3D6D5" modified="2025-10-08" version="1">MPHRVSNFLRNPSASLEAQVASLKKATVRRPSPKPRSSTSSSSSIRAAHGQRTFSYASSLGDDDASDDHHSHNGSVITPPSQEQQQPSHHGTMKTMTSLQRSSSAERREAAHAAEHGVHHRLSFGPLHFGRSSRESHVNPNLTLDWKIESPPIVLYGDAENSTGALVSGLLFLTVKDEPVHLDSFAATLNIHTTQKRPYTAHCHDCIHQYKELQKWSFVQGPMTLTKGQHGFPFSVLLPGHLPASMDGQLVSIAYEFHAEATPQSGTGLPVKLEKLFDVKRSLPAPELPHHSVRIFPPTNIKASVHFPQVIYPIGQNSLSLRIDGVARLNEKSKTLEFWKLKKLTWRLEETTKSIAPACAKHQPPPPADEQSDNTPANKGVQRTDTRVIGEKTLLSGWKSNYSGPDDASVELELDYMLGKHAKYSCDTRTRDGTEVTHQLMLEMVVSQEWAPANKPSMVTQTGVGRILRMHFTDILTQRGGIGVSWDNEAPPIYQDVPPSPPSYNEEISGGQAALPDYIEPLDGVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVC0</accession>
    <name>A0ABR3YVC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00488">
        <property type="entry name" value="PCD_DCoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599:SF0">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="PCD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="226" mass="24059" checksum="674B202B41871839" modified="2025-10-08" version="1">MLRGACRAVTNRVAPPPSSSRVLINLSAPARSAVTRPTFQQVPTSFLAHSRAFSSTTAAMTGAPKPRIVGKTEADEASVRAAFETLVTNGLWTVTANGLGIERSFKFKNFTKTWDFMTAVALQCKLKNHHPEWSNVYNTTFIRWTTHNPGQGLAPGLTIKDTELALLCDELGRAFGEVGEETKPKEDVAPVEQAAADNAACTLSSLANNAAGAAGGDCCTPRPKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVQ5</accession>
    <name>A0ABR3YVQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40624">
        <property type="entry name" value="BIOSYNTHESIS MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12025)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40624:SF1">
        <property type="entry name" value="BIOSYNTHESIS MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12025)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="110" mass="11772" checksum="FF5749F1F04D4753" modified="2025-10-08" version="1">MAPIHMTAVIAPAEGKIDRLEELLVAHAEYARANEPGTLHYDVQRGVNRETGAETLIVWERYADKAAEAAHFNNDAFSKLIQTLGAEALTTGAPSVYVTSSAGGIANYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVU6</accession>
    <name>A0ABR3YVU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferrioxamine B transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SIT1_2</name>
        <name evidence="9" type="ORF">Sste5346_007121</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="566" mass="62171" checksum="B3CFF2906E728C70" modified="2025-10-08" version="1">MDINGSKDEKHVTQPEETTVYDNDPAEAEVTEKLPGVIHMEAFRAAIKPWERWVLFFSMFLVGYAYGLDMLVRNTYQAYATSSYAQHSLLSTINVIRGVIAAVVQPLVAKLSDQVGRLRLFVCVTVLYVVGTIIETCSHNVQSFAAGALLYQIGYTCSLLLLEIIIADITSIKTRVFFVFIPNMPYLINAWISGNVTAAVLGTTTWQWGIGMWCIIYPVCTLPFIATMAIVGRRASKTMPKTTAGRTPLMSLLQDMFWKLDMIGIFLLTASLSLTLIPLTLAGGETKKWQTAGILTPLILGILVTPVFVWWERRAQVPIMPLYLLQNRGIWGALGLATFMTFSYATQADYLFTVLLVAFDFDINAATRVASVYSFCAVVGGVSLGLVIMKVRRFRPFIHGGIFLWLVAYGILYYYRGGAASSSQAGVIAGQVLLGLAGGFFPYPNMALAQSLAKHEDIAVITGLLLTVNNVGVALGGCVSGAIWTQTLYQQLAKDLASNPSLASQVYASPLTVVPYYPVGTPERDAIIHSYRYIQRLLNITGMCLVLPMLAFSLLLPNIRLGKKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXQ0</accession>
    <name>A0ABR3YXQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF43">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="488"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="517" mass="56297" checksum="A0B86D68CB851AFE" modified="2025-10-08" version="1">MGFSIFFAKLSDIYGRRNILISSWIIFVISSVACGCSYDMTQLIVCRSFQGIGGAGLYSLTTICLPEIGPAHKPDVIGKIIGITLSLSFVLGPVLGGFIPQVSSWRVIYWLNAPFAIVAITGIVFLYPVEPTRCHGTNRTLRRVDIIGSLLLLASCVLLVIAMQEAGSLVVPWNSLLVLTSLTSAAICFALFMGWESLLSSGRYWEMEPIFPLRLLKNRVYLSCLLDKFLVGYVYLCLVITVPQRFQIVNSESVFKTGLHLLPMLGGTALGCLVTGPLNAKKNHTSPVVVVSCALMLISVSLLATVNSIAYKSGPLYAYLAVFGIGFGLFMSAGTMLSTAQAQLDDHAAAQGAISQLRILGGVIGLTTFTIIFNTKVQSANVLETLTPMQMDVLRRSPTALVEIWPDLQQLIAGTYSNAFHEMTSILAGISALALLVSFGTLEKNPPPIHRNFNKEKEYLTGRGSDDIELDDAASDRSLVEYRAPIGTDPVPTLYPPPRSHYPNGIPRRPGRTRRWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ68</accession>
    <name>A0ABR3YZ68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="29"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="446" mass="50109" checksum="58D509DFFA7379C9" modified="2025-10-08" version="1">MASKDSVGSLPVRLLNDSYRVQVQHSQRFSLFPTLPAEIRVCIWLGYLRRHRIVGIDLHTESDAGLDDGPSQSSEAPPLSLYSETNELGNLVSGQDYCVVLSPQHKLSPLLRVNAEARAVALGFYRLRLPYSSRRQPLYNGHGHDYDRRVYISPEFDFIHVQLGSGAVRRGQSQRLPRPPPERLADFLYDCKAYDPRGRGVLHLVVGNGDASRFQLPHNPCLVAPQALDAFTSTLVNLQTLYFYIRAGTARIMATELIADRIRYNRGVPIEARCSEDVVFLGNDPRRIEHDLRLVCVGHDPRASLWVWQEMLRAFSINETATATTDLRFLLTSTITIPSTENGRPIRSRGDAKKYAQAEERRWQALFDNTTGPFRGMANPDTPAQVAEAVYAAGFWLVDADAFGAMPERAGFFGQGPRSTTYRWDMKHDATLTAHRPQLGLFSLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZB4</accession>
    <name>A0ABR3YZB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="60" mass="6233" checksum="299CFA06764D00B0" modified="2025-10-08" version="1" fragment="single">VMGTWSWTAPNVGSTGYTNTSKATLVIEMQAPTGTITMQVSDVFFNTCAEGTTAGAQEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY1</accession>
    <name>A0ABR3YZY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GA4 desaturase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36227" checksum="F990E3E365FBF86A" modified="2025-10-08" version="1">MPGVDVKSVRGMVRYNVPDDSVRPEDRGLFSGPAHKSAVDADVDLYDPTTDPNIVQGPEGLDVQGFTYVQHKSALTLEQWMSGTNVEETYIPEVEELVKKVTGGKTVVVNHLGIRKRTAANNTNPTFYRKAGDAHDQAVKNYAGGDKAWVSGRQDAGLEPARFAHCDYTLEGLKRTARYCRKDIKAAAQEALDAEDGKEGATPRRYAAYSVWRPLKAVKRDPLAVADWRTTDIKSLAPIEYRATSNVVPSGEYMLELYTQTPVAKESGQRWYCKPNQTPDDVLILKFADTAAATDPSISGGCAHCSPALDGVDEEEPRMSVEARVMVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1B9</accession>
    <name>A0ABR3Z1B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="355" mass="39285" checksum="9167F621AFAF2815" modified="2025-10-08" version="1">MAAHPRVILGLSTFGPDTTKGARVTDIDEAVGILDYYRSRGYSELDTARAYNGEQQEGFLRKMQWQDKGAVVATKIMPPQRGRTYKATNVFESFETSLKELGAESVDTLYLHTADRSTPFEETLEALDTLHRAGKFRRLGLSNFAAFEVAEIVMTCKFRGWVRPTVYEGLYNCMQRGIEAELIPVCRRYGLSIVAYSVTAGGLLSGAIRTTDTSKIAETSRFSNKFNGPGNNYKERYLKDVVLEARGVIETAASTHSIPLLEAVWRWTVHHSALKVATAANHFDPQRKDGLILGVSSVEQLAQNLDAIEKGPLPVDVVAAFDEAWTMAKGEQANYYRGTLEYTYDAPAVLFGADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G7</accession>
    <name>A0ABR3Z1G7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="126" mass="14215" checksum="A6A62E8FD4A35ACB" modified="2025-10-08" version="1">MCRNQTREPFAMLDLQIPVIAAVNGPVIVHAELALLSDIVIASTTPIFTTATLTTVYRELLGHNRSRYFISMGEKIYAPGAKTLGVVSEVLPLDQLLDRTWEIARTKFLPKNRVQRRLARSLWIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1S0</accession>
    <name>A0ABR3Z1S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TPK2_1</name>
        <name evidence="13" type="ORF">Sste5346_005950</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="226"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="482"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="496"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="128"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="529" mass="58412" checksum="ECC3B4682B548365" modified="2025-10-08" version="1">MPSLGFLKKKRTRDANPDSTSGSQPTSPVTPTATKTFEQAFQQPSNSIASVASAASTTTQPIAATTGSQSSAVRQQAPQPESAPASVSTAKAPVPAPTVVPAPAATMDSTQPHQAQNLVPANPPVSTPSPGTEVQNLPSISNLINPSHNGQDGQTYQQVPTNPPAYSTVPQTTADSQAQSQVPQKQPQAQQQQHHVVPHPGQPVNLQQHAIDLPRVTKGKYSLADFNILRTLGTGSFGRVHLVQSRHNQRFYAVKVLKKAQVVRMKQVEHTNDERRMLAEVKNPFLITLWGTFQDARSLYMVMDFVEGGELFSLLRKSARFPNPVAKFYAAEVTLALEYLHSRNIIYRDLKPENLLLDHHGHLKITDFGFAKRVPDKTWTLCGTPDYLAPEVVSNKGYNKSVDWWSLGILIYEMLCGYTPFWDSGSPMKIYENILKGKVKYPAYMHPDAQDLLERLITPDLTKRLGNLYGGPEDVKKHAWFAEVTWDRLARKDIDAPYTPPVKVGAGDASQFDRYPEETEKYGQAGNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z277</accession>
    <name>A0ABR3Z277_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Basic helix-loop-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CBF1</name>
        <name evidence="6" type="ORF">Sste5346_005680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11398">
        <property type="entry name" value="bHLHzip_scCBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047206">
        <property type="entry name" value="bHLHzip_scCBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="191"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="304" mass="31708" checksum="E8FB46039432004B" modified="2025-10-08" version="1">MTEIAPVEQSPDPTAPGSPSKRKRGAESTSPDARRSKRGAAAPAVPTAFMEATAQDQAAPAEGAADFGAVPAAGQPAVAEDADQTAGAADAAAQQQRTNAANAANAATAAAVLDSMFPQLTVPVPTEETFANQHVDGGEQHHGDASAYSAGDVTQGDLSLDVAGGANGVAKRPMAGIQSKPAVGSEEWHKMRKDNHKEVERRRRETINEGINELAKIVPGCEKNKGSILQRAVVFITQLKENETQNIEKWTLEKLLTEQAIAELSASNDKLKAEIERLYGELETLRGEGAGAAGGEEKTEAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2N4</accession>
    <name>A0ABR3Z2N4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol 3,5-bisphosphate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSV2</name>
        <name evidence="6" type="ORF">Sste5346_005558</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="256"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="416" mass="44835" checksum="5DF74951B7DD688B" modified="2025-10-08" version="1">MDARTPIEGSSNVIALAASFNLNCDCFVVGTNTGLRVFDAATCKLLARRVFKEGGVGLIQIVGRTNIIPLVGGGRKPVHNPLKIVVWDEKREKFTREVPCQRPIRGMHVLGQKLVVVLDEEVRIYVIDRQPVREHSFTTTPNPAGLCAVSRTHFAILGQIPGHVKLVHNETHQVSIIPAHSSELAAIALSRDGSLLATASEKGTLIRVFLTSNNGRVAELRRGVDQVTIFSLGFNPSGTLLACTSDKGTLHIFDIPHQATGDRPGSSNGGRQIGGVPSDVGGDWAYEESDGGVSFASDQRADPNRSKDGGGGRWGVLGKIPFMPKYFRDTVSFASAEFAMDDGPGANRIREADEASAMGRTRLPLGTVGWPNDNTVVVLGTGVEPKYERFVISTGNEGQRVCVRQAWANYLNMDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Q7</accession>
    <name>A0ABR3Z2Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_005597</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="257" mass="26798" checksum="C33A255936D649FC" modified="2025-10-08" version="1">MTTKITSSAQWRQVTSANSIVVTDFYADWCGPCKMIAPTFESLANKFAKPNRIAFAKVDVDNQRDVAQQYGVRAMPTFVILRNGSVIDTIQGANPPALTAAVEKAVKLATGGGASFTTPGRTLASSSGSASGGIRVGGGSTTGGGPIQGRASWFDIRKLISFFTVFFGLYVTSLFSLDPYMSAKNSKYASDKPPPSDRYASGAAFGGRQFNPAGVGACGSMGGPSGTAKVRDPTARSQASTNNNNSKFKTLSDLGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4U9</accession>
    <name>A0ABR3Z4U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="5">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA2</name>
        <name evidence="10" type="ORF">Sste5346_005502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="8">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="7">
        <location>
            <begin position="144"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="9">
        <location>
            <begin position="380"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="510" mass="56745" checksum="E8868C5FA1F51E74" modified="2025-10-08" version="1">MTDPRVSSSFNINPHITYNTVGGANGPLVILDHVKNPRYNEIVNLTLPDGSVRAGQVLEARGSRAVVQVFEGTSGIDVKKTKVEFTGESFKLGVSEDMLGRIFDGSGRAIDKGPKVLAEEYLDINGSPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVQRQGVTNKGVHDGHEENFSIVFAAMGVNLETARFFTRDFEENGSLERVTLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLTSYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRALDNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSAEDKLSLEFLEKFERQFISQGQYESRTIYESLDLAWSLLRIYRKDMLNRIPAKVINEYYQRTAERKGKAKADNKPSRDEDDQEEENLIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5F8</accession>
    <name>A0ABR3Z5F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="30333" checksum="8DC5C37A7D4625CB" modified="2025-10-08" version="1">MTSHTFVSQPPAVPDVLVTFPAQHVMLVTINRPRQLNSLPSTYHAPLDRLFKWYDNEPALRCAVITGAGRAFCAGADLKEWNDRNAAATKPGASPEAKTERWTPSGFGGLSNRTGKKPVIAAVNGICLGGGMEITVNCDMVVAAQSAVFGLPEVKRGVVAIAGALPRIVRTLGRQRSAEMALTGRNYSADEMEKWGVVNKVVPDDKVVAEAVAMASTVANNSPDAVVVSREGMRLGWEGVAPELATDLLERGMYGIMDGAENMKEGVLSFVERRQAVWKGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5G1</accession>
    <name>A0ABR3Z5G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RMT2</name>
        <name evidence="11" type="ORF">Sste5346_005714</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="10">
        <location>
            <begin position="193"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="144"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="448" mass="49042" checksum="FF21A8BFE5F8DF64" modified="2025-10-08" version="1">MTDIDDSLDARISSECPVGVQAILRAAWRHDVDALKPLLDAPGKASCRDPVTGETPLHAAIRSLGPVDEEESAEVQAEKEAKATRMVERLLFGGAIWNDVDTNNETPGCVAWRLNQKELYDQMVRAGARAEMLFAILDGYEELESDGDEEEDDEEMGEAEAEAEAEETANGTNGHEAEAEEEVPEDEPGTDAPVSEETSYLESHLTLADGKLVDSAGNGVMMEWEADIMRRSVDAMLGGPPEDESTKGKRVLNIGFGLGIIDSMIAARQPARHHIIEAHPEVLARIDAASSNPATAGDDHAAEFGAAWESSGPEEGAFKVQRGRWQDMCPKLLAEGELYDAIYFDTFGEDYSELRRFFTDYIPGLLNDDGVFGFFNGLGADRRVCYDVYTRVVEMHLSEAGLDVAWNDVDVPLAQDGLDKAGAGAWEGILRPYWTLDKYRLPVCTFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5V5</accession>
    <name>A0ABR3Z5V5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crh-like protein</fullName>
            <ecNumber evidence="14">3.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">UTR2</name>
        <name evidence="18" type="ORF">Sste5346_005104</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017168">
        <property type="entry name" value="CHR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF22">
        <property type="entry name" value="GLYCOSIDASE CRH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037299">
        <property type="entry name" value="Glycosidase_CRH1_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 18" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499544" description="Crh-like protein" evidence="16">
        <location>
            <begin position="22"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="17">
        <location>
            <begin position="64"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="346"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="383"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR037299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1895634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="454" mass="47508" checksum="77B9C6FDEAFCFDB3" modified="2025-10-08" version="1">MVRSILPIGVAALMGATGVLAADSIPTCSLTQKCPESAPCCSQYGQCGVGAYCLGGCDPRMSFSLDACAPEPQCVSRVMKMDSLDRIVDVSEYLGDSSKADWVAQGTPLVYNNEAVLLTMPANSVGTVLSSTGYMWYGNVKATMKTSRGAGVVTAFILLSDVKDEIDYEFVGTELDIAQTNYYFQGILDWQNSGNITLSDTYENYHTYEIQWTPDSITWLVDGQVGRVQKKSDTWNATANQWNFPQTPSRVELSIWPGGASSNAPGTVEWAGGPIDWNSADIKNYGYDFATFSEVEIQCYNASSAPGTNNAVSYTYNNWLATNNTVVNGNKNPIMKNFQNTGLDMTSGDDLNASSTSSAAGSKKTSSNTIPGGTSNGPGSSQGNGDTSSGSGSDSGSSGSSTGSSSGCSTTGFSQNCDSGSSSKSDGGRVVGGERIIGASAFAVVIALGAMMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5X4</accession>
    <name>A0ABR3Z5X4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="29812" checksum="299C076C691CA9F0" modified="2025-10-08" version="1">MSGALFEMVAKRALRDTAKKNINSKDPYYEEVAIYGRNGRPTGKVKKQKKGIPAILSHNDGKVLKKVRKQAFRLDMSLFNCCGIRFGWSSVIGIFPVIGDAIDLLLAYLVVKNCAKIDGGLPPSLQYRMYFNILLDFGIGLVPFVGDVADAIFRANTRNAWILEEYLIKKAEAEREIQAEKDRRDRPPRDSGIAAGGTSGAAGASASAAGRAHGERPAPKKSWWSSWSRSGEQGGVHPEQEMAMTDVEHGGGGSSSRAPGMYSGGQQSGVTHGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6N6</accession>
    <name>A0ABR3Z6N6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA polymerase</fullName>
            <ecNumber evidence="15">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">REV3</name>
        <name evidence="22" type="ORF">Sste5346_004679</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="15" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 15" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 15 22" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="21">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="20">
        <location>
            <begin position="82"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="18">
        <location>
            <begin position="715"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="17">
        <location>
            <begin position="948"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="17">
        <location>
            <begin position="1135"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="19">
        <location>
            <begin position="1555"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="322"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1896296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1649" mass="184669" checksum="0D38DE6654462F87" modified="2025-10-08" version="1">MYQVRIHCIDYCLAVPSKADFAASRAPIARNNRSTNKDANKDGGNGNGNAADQATDKEVRVPIVRIFGATASGQIACAHIHGVFPYIFVPYESFQFEDVDRIISTLHNGIDRAVGRATVLSITFVRGIPFYGFHVGFRPYLKVYLYDPSQMSRVAEMLRKGRIGGIPQLMPQESHIPYLAQFMTDYNLYGCDLLEVTESEVSPRPPGPSTRSCPVEVDVAAFSIRNRHFVPERWQHEDLPETPNTPNERLVYSMAALWREMAARYNKKGKKSAEERKVWEMISTQEAFAQLGASSSDPRRTPAPWIHEEEYREQIADIIAAERIRDTRPRPREPLENDLPTIRQSVEDFYPKSARADNKKRKLGCTQSQESTTTNGNDPKKAKLQNSRRQDANSPSPPPPDFEQQLVPILATHEKANDKVTLSNEWLRNQQSQTEPRQSQEPPTRRKRNDDPKDSHRPLSQTFPVVKSAFSRTEDAKLSQSQTISELEGGYQTEEQSEDQIEDEDDDEDDDEVDLVIPSTPDNELEKLSTPRHTNKTKKYEADTILGTQDRVKLGASHGPFYYVTENVLLLFQRPPAVSDVMASLGKFGAAELHQDAHFSDASDFQKNKNSHAAAVNVVPVLPAFSPFPDSGPGISHRHQTAPLQSGSTKSWEFALLPPSQASVEAWLEAEQQEEEAAKKKEALELDSTQRQMTQSQLLQEQRAALRTPKTGLQLDMRTLCLEVHADSRGTFLPNPERDAVQCVFWRCSGGGEIDTSEDIGGLHIGGKNGGVISVARSLRDDFCIDVAEDELDLIRLVIRLVHLLDPDLLAGYEIVGSSWGYLKERAALLDIDLWQELSRVPQQRVIPFHERDQGVTGRYMLSINQAMRADVDLRQYTLENAAWNVLGRRVPFYRPEVLTAWAASGRPIDFSRLMRHYRRRTAIGLALIESTELVSRTSEQARVLGVDFASVLERGSQFKVESVMLRVAKPENFVMPSPNHKQVGQQNAAECTPLVLEPRSAFYSSPVVVLDFTSLYPSLMIAYNLCYSTYAGRLDPMYHEKKIAAAATAAAAGCPKEATANHHLQENHDKLAKNNIHDTNSSIEKDDITQQKAACAVGENTVELIAKHQEKSATKMGFTTYKRPPGLLERLSQLGLVVSPTGTIYVGARTRQSLLAKMLAEILDTRAMVKAVMKKTAANKVAERQRLHNRQLALKLLANVTYGYTSASFSGRMPCVEVADSIVQTGRQTLDKAIALIHSVQRWGAEVVYGDTDSLFIHLPGRTREEAFKIGAEMAETVTAANPHPVRLKFEKVYHPCVLLTKKRYVGYQFDTPQQTEPIFDAKGIETVRRDGSPASAKILEECLRILFDTADLSRVKAYVQARFEDVMNDRLSITDLCFAKEVRNPTSYRAPPPGAVVVSRRMAQDPRATLVHGERVPYVVISGPPDMPLRDRCVPPEDVVKNRNLRLDSDYYIQKSLVPPLDRIFRLVGVDVLRWYLEMPKARMPLRVVDPAPTQVMGGGGEGRSGGGGGGNVNAAFMGQQTLDTWLRGARCARCDRPVRRKRRRWPGTAKSDNKKPVLCKTCGRDNLGTLAYLQTKARDTERAYQAVVDGCRSCAKLAPRDEVRCENLTCPVYYVRVERAVEAKVERAKAPLVEALARRGMRDLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Y9</accession>
    <name>A0ABR3Z6Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1308 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379">
        <property type="entry name" value="UNCHARACTERIZED DUF1308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379:SF0">
        <property type="entry name" value="UPF0415 PROTEIN C7ORF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="664" mass="73010" checksum="B3FB4277B9407B10" modified="2025-10-08" version="1">MESDCLETNGQSALNGQVERLSLNDSTAVDTAHATAAPPSQPSAVDDSPPGLVARWAVLIREYEAFQDALRVRVRQPYWPGVRPYISMLQVEASQSQRLAEGRFSDQPDKQRGELRLAMTTLAAKEGMWRIVKTCRGVMALDRRFQKPTLLPTEAVAARTAAVEAKKKRYHVVNTGSRNEGIFVNAVVDDGRTWLRVLTTTSAQLLIEMADNGWEWGVGEDDSDEDGDEGDPLEDIYDMSLVEFALDLIEAAHANRFKGAYPRIDIILTRIEETADDDEQDDKKKREAAEIARYLDKVRRGLKKKAASLPPDIDNQQMHIDVYTARDPRTLAQPPADLDVALQNLMPTLSDRLTPTLNIDTSILIALTSDITHSSVTPQDWFPAQRLEEIAREAKKPGDVLRSLMGDALHGRQLVCTQEAARAFRVMVSDMAQPSEQERARLLLGEGDKTSLSRQQLVDRYRELSSYPSAVPDDLMLPIRVETEAWDVERIRVAAGVLSSGEPASGDKVGSAALPQSPQSPQSSSVTLPAVTTQVVSDMTDSQPTLSVFFYGWAARQTTITTNLAARNKIARLLEKYRTSSFEEGPLVWVCRTARSLNGTNPRDGRKDGKTPKQKTGAETNGSQSTSPSTEFQVARQEDSQGNVGKAGPSLDPAVKIAANGCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7H4</accession>
    <name>A0ABR3Z7H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MRPL44</name>
        <name evidence="7" type="ORF">Sste5346_004869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019716">
        <property type="entry name" value="Ribosomal_mL53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042776">
        <property type="entry name" value="Ribosomal_mL53_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28236">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L44, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28236:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10780">
        <property type="entry name" value="MRP_L53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="97" mass="10940" checksum="F1A2715C0224604C" modified="2025-10-08" version="1">MLTRFITEVTTRFNPFSAQSKAARLFLTQLPPSARQNGMVVTTQLLPRTSTEPSTLTVKFKDGKEMKLDCEEMGIKRVVEEVDRHSRALQKAADLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z870</accession>
    <name>A0ABR3Z870_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="81" mass="9204" checksum="D4F88B9C5CB9122A" modified="2025-10-08" version="1">MGNCFSRDIDGYDRRTRMPPGGSGYYYGPNDMPPPPNGDYNMRIYDKRDMHPLGHRRRRRNRRGRNTAAIVASTAAAVSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z887</accession>
    <name>A0ABR3Z887_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="270" mass="31707" checksum="FF7E1812A85BDA39" modified="2025-10-08" version="1">MGDTEAPRPRSSPDPERRKRPSRSQSPVRERSDRDRSDRSGRSDRDRRDRDRDSYRDRDGHRDSHRDRYDDRSDDRYRHPDRRDRDREERRDRGESSRKDDNDADYGKSLADDRPKPKKKSGGGFKVKEKKRDDGEDEGDRGFDRRDRDWSPRRDRDRDDKPKDKDSSKSKSGDGEKKEKKKKKARAPAPPQEFMIVHVNDRLGSKTAIPCMGSDLIRQFKVMVAARIGRDPSEIMLRRQGERPFKDHLTLEDYGVTNGVQLDLELDTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Y6</accession>
    <name>A0ABR3Z8Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SER1</name>
        <name evidence="13" type="ORF">Sste5346_004569</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003764">
        <property type="entry name" value="PRK05355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247:SF1">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="9"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="186"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="437" mass="46595" checksum="266DC585BF0E3F8F" modified="2025-10-08" version="1">MPGRNDITYFGAGPALLPTDVLERAAAALVDYNNGGLGLAEISHRSEPASAIVREARADLATFLDVPTDEYEVILMQAGGTGEFSATVYNLVGAWVLRERSKLVAQGLPDDDKSPELISALRAKVDSELRLDYLVTGSWSLKAYQEAQRLLGADKVNLVADARKEADTRAGTPSKFAAIPDETSWVSKLSPNAAMVYYCDNETVDGVEFPQFPPALVPSAGNTSAPIVADMSSNILSRPVPVRNYGIFFFGAQKNLGSTGITVAVVKKSLLPQPSADLLRALNLPIGPIVLQYETIAKNDSLYNTLSIFDVYIAGQVLKKLLAAYPSDKAAGQQAVSVRKADKIYAALDAHQDVYRIAPTPAARSRMNIVFRVVAGSDGGDAAEKAFLKEGTALGLTGLKGHRSVGGIRASNYNTISEEGAAKLAAFIDDFAKKQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9M5</accession>
    <name>A0ABR3Z9M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="11">IMP dehydrogenase</shortName>
            <shortName evidence="11">IMPD</shortName>
            <shortName evidence="11">IMPDH</shortName>
            <ecNumber evidence="11 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">IMD1</name>
        <name evidence="16" type="ORF">Sste5346_004419</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11 14">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="11 14"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 11 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11 14" id="KW-0520">NAD</keyword>
    <keyword evidence="7 11 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 11 14" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="128"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="191"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="11">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="285"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="335"/>
            <end position="337"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="11">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="11">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="11">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="375"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="398"/>
            <end position="399"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="423"/>
            <end position="427"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="520"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1896786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="538" mass="56973" checksum="873B90EE0DFDF68C" modified="2025-10-08" version="1">MPEAVNGVNSFLSASKALATLEEYEERDGLGIKDLMNARVHGGLTYNDFLVLPGYIGFPASEVGLDSPITKRITLKTPFVSSPMDTVTEHEMAIHMALQGGLGVIHHNCSPDAQADMVRKVKRYENGFILDPVVIKVGTTVGEARALKEKWGFGGFPVTENGTLGSKLVGIVTNRDIQFEDDDSQPVSSVMVTDLVTAPAGVTLAEANKILSQSKKGKLPIVDKEGNLVSMISRSDLTKNLHFPLASKLPDSKQLICAASVGTRPEDKIRLQKLVDAGLDIVILDSSQGNSMYQIEMIKYVKATYPDLDVIGGNVVTREQAAALIDAGVDGLRIGMGSGSACITQEVMAVGRPQATAVYNVCAFAARFGVPCIADGGIQNVGHIVKGLCLGASTIMMGGLLAGTTESPGTSFVSREGKLVKAYRGMGSIDAMQDKKAGGGSKDSQKSNAGTARYFSEGDSVLVAQGVSGAVAHRGSINKFLPYLAAGVKHSMQDSGIKSLKELHENVASGKVRFEIRTASAQLEGGVNMESYEKKLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q8</accession>
    <name>A0ABR3Z9Q8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_004054</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037654">
        <property type="entry name" value="Big1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046756">
        <property type="entry name" value="VAS1/VOA1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285:SF1">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20520">
        <property type="entry name" value="Ac45-VOA1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046700995" description="Protein BIG1" evidence="11">
        <location>
            <begin position="18"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="V-type proton ATPase subunit S1/VOA1 transmembrane" evidence="12">
        <location>
            <begin position="236"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="30432" checksum="F76CF6E802EAD4DA" modified="2025-10-08" version="1">MRASILAGLLAVGTAHAFSDSSPFLLFSTADLPVEPSSQFQTSARVLASAKALLADCPTTKYLLVSQPNAHASDLYSPPSCEAHRLRRALSSNEVKGRFTVSEVVAPADKSNNLTLDAFSSHIKASCGADVTVNELSLPALPLAPTCQERAEALGDNDYVLGNALDGALALGDVTVVYFSNGNAAAHGSGYEATFEDPAQVPIKKRLAEHHNVRQAAPAASDKPKRDTRGLFEKYQFFTPGIFMSLIVFFILLTILYVGLSAVASLKVPYGAFDKDMGPSAQKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL3</accession>
    <name>A0ABR3ZAL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SFT2</name>
        <name evidence="9" type="ORF">Sste5346_004280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="23490" checksum="C6A7EFD08795511A" modified="2025-10-08" version="1">MTSQSFRDSLNSLGWSRREADVPVNTSQRTGLLSSLQSLNPFGDGGGYVSLPTTEGAGAPLPAPTRREEEEGWFALSRWDRLLIFGGCNLGALACFVICFALFPIVATRPRKFVILWTLGSVLFLSSFAAMMGPWAYVQHLASTPRLPFTAAYFGSIALTLYFSLGLHSTILTLISAIIQLACLLWYLVSYFPMGSSGLRLATTFGARRAAAWMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAV1</accession>
    <name>A0ABR3ZAV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004007</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="9">
        <location>
            <begin position="430"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="161"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="776"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="6">
        <location>
            <begin position="461"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="780"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="846"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="902"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="463"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="918" mass="100402" checksum="7B40D5CB167704C1" modified="2025-10-08" version="1">MAEKSRGGPAEAVPSLYGFPTDTLDDITQLPDYDTDFISPEDLEAFVQALAAPDPLQSPTATVSAVPGEEGNPLLSAGGATPATLSKRNSIVSNTDGAGSAIGGADGSFFITAKNDWAPVNEKVEGPEGSASAAAPAGRRRTATFISASSQWLPSFFTWKKTPASSNTTQSGTGTPSSKRSRRQEQQRRRAAAASTAAGKRSRKRDKPGVSSLGRRTRDETREGYLYGLLKWPFLIGVFGWIIGLSIAYLLTRMYIAAYEQLVTWRGRRERLRHRMRATDNYADWVAAANALDTHLGNDRWKEENEFAFYDFRTVRRVADQLRKCRARAEAAEEEKDGKAAAKDASGGSKKDNVGDLKALVEACVKNNFAGIENRHLYSRTYYGTKNLVQSFVDEVERSLEFLINTNQLDAAEKRAMFKRLYANYGRTALCLSGGASFAYYHFGVVRALLDEDLLPNVITGTSGGALVAALVATRTNDELRQLLVPALAGKINACSEPLAVWFRRWWKTGARFDSVDWARQCAWWSHGSMTFREAYERTGRILNVTCVPADPHSPTILCNYRTAPDCVIWSAVLASAAVPGILNPVVLMMKTPGGRLVPYSFGHKWKDGSLRTDIPIKALNLHFNVNFTIVSQVNPHVNLFFFSSRGSVGQPVTHRKGRGWRGGYLGSAFEEYLKQDLRKWLKLLRNLELLPRLMGQDWSELWLQPFSGTITIWPKSIPSDFVRLLSDPDPPRLARMLHEGRQSAFPPLKFISNRLRVERLIERGRFQTRSLAIAGGATGAPNTANAGSASASGTNNNRGRGALRLTGLGGPGHAISSSLDSAMSDDDLNGRARQRRRRRDIASGVGLGLGTMGGGLGSTTATSDENNYSSDSDDDLDLSGGGLGVAQVLQDSYDESGKDIDYDDEEVPIVEETDADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBB6</accession>
    <name>A0ABR3ZBB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004066</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045164">
        <property type="entry name" value="RBM41/RNPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16105">
        <property type="entry name" value="RNA-BINDING REGION-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16105:SF0">
        <property type="entry name" value="RNA-BINDING REGION-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="25"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="200" mass="21137" checksum="C73B39BB89E4D6D6" modified="2025-10-08" version="1">MSTTVSSRGPPPGAPPGKAAVPPNQTLYVHNLPSAKIKKDDLRTALYLLFSTYGTVLDVVALRTMKMRGQAHVVFRDVQAATQAMRSLEGFAFFGHELKISYAKSKSNVVARLDGTFQLPSAAQTVEVTDLQQSIFNAPAPGAPTSSTSAAAPPAAAAATGAPAAADAARGQKRTRDEEEEEEEESDDSDVAMEEDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBF9</accession>
    <name>A0ABR3ZBF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1898013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="22343" checksum="0AC427EA1BB34AC2" modified="2025-10-08" version="1">MPFKLTEICFSDWHMRGGLATRGVLIDYKAYADRKGLNYSPFSPHKVTVDVMDAIAREQGVTLQRGDVLILRTGYMESLQAIEDVDLQEQMASCPDSVGIEDSMEAVKWFWNHHFSAVAADNPGFEVMRPTVNGVDGSGTTADYVLHPNLLALLGIHIGELWDLKRLSEYCNKTGRFTFLLTSMPLNVPGACGSPPNAMALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBI7</accession>
    <name>A0ABR3ZBI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF30">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="56490" checksum="EB221D2DD7D3EA61" modified="2025-10-08" version="1">MSHSSPPSFPVHRLNTTTPPDNLAWDDFLRTRTTLNTRFHALVTCSVTIASVAHSCVDLFTQFLFPNTPIAHEPTLRASIPLLSVDDTPRSAASTDAVPSLVRRFTLITALCAHILSIVPESLSRQPQAKALSIVFFDASRGMLRAYEGYDLEHPDSTSLTIRMWHSSCAQNTTGKVGASWHYHTEACCLAQRLRLYDEETVTQYPPLERRLLRNNFWHLYLAEKTQVAFQTRPPIIDEKICYGGITLQEGGNEDEITTVPLLDPRRPENGGSLERRILVGFHLRRRISAIAAALIDDVAECGRRTKTADVSSPLSPLSPSTDIIIDPSVSTLVERYLCFAALINDVPSWVMHPDRDTNPLVGNDDVQAYHATSFWAQRSNILTIFHCMRLLILQACIDHGLPVVVGLTSSSLALASRKLDIVRDFLHDVQATPFVVLEAQGETTVDKVRRVGTLLLELLHTSDNATIRQQADTLFKRLLDILSRLDSKACEGLDGDGTWRGLSAADIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCU7</accession>
    <name>A0ABR3ZCU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="204"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="431" mass="45082" checksum="6C8BFBFE47794DCA" modified="2025-10-08" version="1">MALSAEVSAAGIEAQLPVLSEMNNFIHSNPELAYEEVKAHDHFVEVLTKLGFKVTPHAYGVPTSFLAEYGEGGRLVVFNAEYDALPKVGHACGHNLIATASFAAFLGAVAALKKAGTPGRVQLLGTPAEEGGGGKIKLIKAGAYKDVAACLMVHPAPSAASLAAAAGAMGGNDAAGGMGATLAKAAASGVREVAYVKMLACVKYSVYFKGREAHAAMAPWAGVNALDAVCLSYNGISMLRQQIHPHERIHGIFREAGTRPNVTPAHTAVDYYIRSDTLSHAEALWRRVKNCFEGAATATGCTVEYVPIDTYADLRSSPGLCQTYVDSQPKGTVLYSTPIDFMAGSTDMGNVCYECPGFHGAFGIDAPPGAGNHTPGFTSAAGTEDAFQRAVACGRGMAATSLRVLSDDEFAASIYSAWQDDMKAAKAEYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDM4</accession>
    <name>A0ABR3ZDM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">JEN1</name>
        <name evidence="8" type="ORF">Sste5346_003664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="61"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="58821" checksum="47CF4D9361D5A3A5" modified="2025-10-08" version="1">MADMDKTGEQQHAEFTDLPPHHGMSTGQYVASRFTSLKPVMAHAPNPIRIITSLNRRQWAFFSVAFIAWTWDAFDFFTVSLTVGDLAETFNKTNTQITWGITLVLMFRSVGSILFGIAADRYGRKWPFVVNNLLFIVLELGTGFCQTYQQFLACRALFGVAMGGLYGNAAATALEDLPEEARGLMSGILQQGYAFGYLLATAFARGLVNSTSHGWRPLFWFGAGPPVLIIAFRLMLPETDTYQEHDAVRKAARVHGDTAPPSATKTFLREGKVALRRHWKLLTYLVLLMAGFNFMSHGSQDLYPTMLSNQFKFSANAVTVTQVVANLGAMLGGTIVGYCSQIFGRRITIIVMCVIGGALLYPYTFVTNKGVIAAAFFQQFCVQGAWGVIPIHLMELSPGAFRTFVVGTAYQLGNLVSSASSTIESTIGERFPLPPLANGTKRYEYGKVICIFMGCVYAYVIILTFIGPEHLRRKFDVAHDADLRAVAGDETIVEAMHRRERMGMGLSNEDLEDAAAVHRDEEREKATTTRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDV4</accession>
    <name>A0ABR3ZDV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="81"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="730" mass="80097" checksum="0DFFF6F9335CBD90" modified="2025-10-08" version="1">MACQACRMRKIKCDRTRPICQNCRLRSSHCTYAGERRQRRHTDVGGGPPRVTAVQIQRRQQEYTPTGHDYSSIDSTALLGNTAPPFVSTHGHSHNRGSPGSQGSSHSLLDGILGDDVGEVDSDTTPSSSPRNPAVWMRLQDGDEYTGPSSGLAAISDVGLEWIRAHASGVEDADADGLCATIDEIRTVLMSHLRQPKCVPPEALHTSVMGLTPLPPPALIRQYVDAYFSSVQTLFPVLDREEFDALWEMYGTSEDMGPPSWHALLNAVVASGCRAALSDEETAAAFQASGRAAWAFFQNALAYEPLIIHHATDLTAVQAMAALTVFAQGLSSPQRLEYTLCSMAVRLAQGLALHRRPAAEWGLTEAEQRQRDRVFWVIYGLDKTIALRCGRPAVLQDDEISCRFPRQVRVHQDDLQGLDLFLCFTRMTRICGAVARQLYSVAALSTPSAQLKGTMDQLLADVAQWMESIPTRLRPGRPIHSIATSTAARMQLLALHATYFYVLCAIYRRFTPLFTPGEEANPETIKGIVEAARALVLLTKHLDVESFTPAWLVFYYPMTALTTLFVHVVATSSTHTTTDASSTRNDMALMEVVVGFFGRLEYVTSGEAAFTKTAEFVRQARIITKRGEARRSVPGQAQQQLPGVSPTSITSVINADTGLTTNSDTGSVPLDITFSPRTLDTLRSLQDQSFQDFLDSTAPMMAFNARLDAPSKDTLTPGAMYNDMMQMLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEM7</accession>
    <name>A0ABR3ZEM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40635">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40635:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="344" mass="37782" checksum="479579B9E469D2B8" modified="2025-10-08" version="1">MAPVRRYLRISKYSVLECRIYVDNPALVQSWLLHPRDPVLPRVIESKGAIRDVLVEEDFEVSLFLNETNTRHSLLFKHRRARDKTQTRLVSNSSKLTGGMSDAPIDVENGSSGDLRVEIDQDGNDENDDGDEDIVLTAASVGGSSRRQADPEAPPPNLLLEDSDEEVPLALQDIPDIQEVKGEDGSTEDTTTRRSKRRRQDPVQVRDSDDEDEDGGEGQDGADSDNDSLFMSDNDNEDADAPPSKRSRIVPVDADMEDESSRKKKKLAMDVIYEGFAIYGRVLCLVVKRRGPPRGRGAQTVLPVSVGSGRAGNASTASEPMKPGGQAAMENWIASTQIPIPQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZER9</accession>
    <name>A0ABR3ZER9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRF1</name>
        <name evidence="6" type="ORF">Sste5346_003103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="229" mass="25939" checksum="9B3BF32368EEE2B2" modified="2025-10-08" version="1">MATPSGKAVAKPDPKDVVTNPRGIPQAPFVDKVEDYVTSREDVEPTLRRFQEMISKYQFMESNLQRRVSGLDEKLPDIQKTLDTVRFLQTRRPGAKKEANDSDDELDSDEDETEDGEAIETTFELNDTLYAKATIPPTDEVYLWLGANVMLSYPIDEAQTLLEQKLNSAQTTRRNCEEDLEFLREQITTMEVAIARVYNWDVVQKRKEKTEAEPTKGSSSKGGVDEPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEV2</accession>
    <name>A0ABR3ZEV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF6">
        <property type="entry name" value="ISOCHORISMATASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="13"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="202" mass="22038" checksum="95F366A3BDE3BF49" modified="2025-10-08" version="1">MWADEMADTNTRTALFVIDIQGELANDPATQIPYADRVVQAGTKILQSARRAIADASATIDDKTPSIIVFVQHEETDGGLVRGSEAWKLVFPPQSGVDTEILVPKTTRDTFESNPDLAQRLRDLNIGRIAAFGIQSECCVLSTCRGALAAGFDVTLLSGAHSTYDTDDKTAVEVERDVEAELHANGAHIVPWEDVARTWERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFL9</accession>
    <name>A0ABR3ZFL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit SPC34</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein SPC34</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Sste5346_003076</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="Spc34"/>
    </dbReference>
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        <property type="entry name" value="DASH_Spc34"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="269" mass="28957" checksum="14A7542F18787D85" modified="2025-10-08" version="1">MSHLMVHLDQISVSCQGIRSLPFLPPKVFTNALLYNDDITSLIRDTEAHERALFSVPAPPPAAKATLAETAAEAAYKAGEADSAVPSSKRRQTVFNVAAGEVTTGPPSARPSAAPRRQTAVAAVLGGDLHAQIGRRIGGGSGGGDVDVNILLKGAEKLCSVYALPGALERIPVLRQKHAQQTSTLTYYEAKVAEQAQRLEGMNRDRRGGDEDYDDDMSMAAATPAAADGPTEEDLRQEEDEIRELERKKKELQERLRAMDKDLGGLLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP4</accession>
    <name>A0ABR3ZFP4_9PEZI</name>
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        <recommendedName>
            <fullName evidence="3">SANT domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">Sste5346_003301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="entry name" value="SMRTER, ISOFORM G"/>
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        </source>
    </evidence>
    <sequence length="2682" mass="287638" checksum="07D7531F6D78DB9F" modified="2025-10-08" version="1">MQSNTHRSRYTGRYDSDRRSRSPPPLRDRDRSPSDRYNDRGSSQYGDNERRRLSGENRNNQPPFQSNRDNRDNRDGGNFRDANNSRDPPRGPKGGLGDRADLPGAPRGGGFAGDFRGRGRGGGQGRGWMREDSRDNKGPRDRDDFRDRRDPPFRDERSRERDWRDRDNRGDRGDREFGRRWNSPPTMGRGLRSPPGRGDPPGRGDGPPSRGEPLRGDSIRGDSIRGDSIRGGDLARDNARGDGPPGRAEGNNRDPRDMHTPLRDARDILNTRDIREIPLGGLPDASDRPRRGSRDGPLSAGSASSDPVFNSQSYRGSTPGRGRPAAGRGRPQGDWDQRGRGGRAGSIYDDRDRFPRSRSQEGRWPRNDRDDRDNYRYGGGHDGDQRSGPRDRDDRGDPRDARDMRGDRDGPPWPKQDRSSLPRDTIAREPISSRDPVSREPPSREPSAREPITRDAAQPPASPPPVAPSAPAFGSIPARPPSIADTSSAKAAAAAATAKSSAGDDKDKPAASSTTQSSTTAAASSTDTSSTMPAKPPPTNSSTPAGPRLQQPLPPKPQRASSVQWVNPASKDKDGASTAKPSTSDSPKPGRSPNPATDSAPTKPTASSSSAAPEKERESKRPRTDDKDAAVSSTSTDTPMPDADQQSEPGEIADNAPTPVAKSAAEKPAAATKPARSPLPTPSSSASDTKRPTGIFARNAALARDTAAAKASKTSTPVSKQEEDKKDDKEKGSTKEKEPVKDKKPVTKEDELPPREKKPQSGPQQVAKPSKAIDTTKPSDAAKTAKTPVPADRSEKTDKTKESVKDSIKASAPTTTTKPDEPPVRIGTVLKPLETIKDVRKEVAKVQEKQDKEKAAASAKESLTKADDKPVVQQSLPVNVDALMVSVRRGSPASTAPDRTSDSDEEDMNDYFDVEIEKHEAQLKKLRDQAEAIPKEGIARVALLESFLTKDLLEANIGMLDVVGAVPEETLAAWKKAELESKKIKEEPETAPLSTSALAADDASKATITTTDKPATDAAATVMPPKTPVVGSGPAAADKMDVDSVAPPAATSPTATKPVLTSPTATARAKTPVKTEKKPAADVTTTTTSTSAIPVPVIPTQTPAASAATTTSANAPIVPVSNGTLPIPKTSADSPPGLDQARPSSPSQPEEDENATDVDEVVDLSYPDVARFFMKTPPLEDIPDYSMSPWYESENRAALDEDDMTPGAEDYILNHMRQLDLAKTAKQQGQREQYRDNYVKYLQFTESDDIVAVKSRDKYMGIHGMAEIPAPATPPAEPARPEGGRGTGRRFATERDLERVLQASMREEDERKERELRAQNERYPSTKEATIPDMYWRDEERVQTLFIDRSGFLPPEKMVTSWQVLPPVINFTPEEVALFEKAYLEFPKQWGRIAEMIPTRDFHACIQYYYTVKKELNLKEKLKRQPKRRKKGTRGKQRSSALVSELGNPDENEDSAANETGENGERRRPRRAAAPTWGFETASASAADSDGATPAGTPGRRRGGAAAAADGTEKPDGRRNRRRAPKDKEKDKQDKEAKDSAAKEAKDGKDGKDPKDLKEAKESLKEGKEPKEAKQSKTPQILAPTPPGTATGSGKSGRSRSNSRVQGSPRPPSEHSNQQSLMPPKLQQHRKDGAPPTVTPIPAPSAPPAPRMGHYYDGPPSTPHSGMHPPTLASTPAATTPLGTPDSKTMGDVGNGRLGYGAMVEKALTPASAAASQAQQIGDMLAPPSLRPEQPPPPLQIGITNFDANVANNNPNNPVSTNSERFRSTQQTSSYWSVSECNDFPALLRTFGTDWYAIAQHMQSKTPVMVKNYYVRQKNEKKAEWEAIANEANMRKLHGEKMPTPPPPPIAPRKRAEQQATPSAGVAAAVAATGAQQRTLVATSKAAVVGGEPMEDIKAEGAAIQPQFGRYQTPVPIAQAPPPAPPLPPQVGGHQKPSVSQSSAGQVQPQVVQPTPPSHGKRQSQQPSAPVSVSAVPLPQQAQVAPPPSAAYQQSVLMPQGAPSSSQAMSPTARPMRGPTQSVVPPPYGAAAYHDSREGSVPPGPQQTQTPVPVGSSRLSQKQPPPPPPSSAAVAAASVPVESLSRPTTSWADPTSDAAVDARLNSLAQRHRQQQEQLQQQQQQQMRSEVPVSSRQPSGRMKEPEPSPSSVYDPYATSTPGRGPPPPPPSHYRTNEPGRPSDPMRVAAHTPPQPYGQSPAPIIQHQQPVRSLLTEPVHPQVMGGVDRDRHVRHDSRPPMHGGMHDPYASSVSVPPPTSTPTPTPAANRPAKTSSLMALLNDDPPAAPKRVNDVSSSISAPPSSSTPPPSMVGRNPPPPAPHHDAGNPVYSPYGRSHPPPPPSQSQSGIPPLKPYPPPAHNSPQVHSMAGPGGSRSSVMSPVESAAAADRDYYSRHPYQSQPPPSSQQQQQQPPPPSQSYPQQQQTPQPGGYGGGYGSQAPPPLAPSPTPQYPGRPPPGRHDPISQGRDGSGWSQGPPPPSHHYGGPAGGPGPSQQGPPPTSAWGAQQPPQQPPPSHHHNLSSGGGMRDDRTYPPQDPRDPRGDPRGDPRMQQAPPPQHAHSHSHSHSHSHSLSGRYQPSPVPRSVEPAPPPQSQPPPYGRYGAGPPSGPGGPGGPGGPVQPPPPSRDPRDAGRYTPVGYDSRGPPPPPGPPNDGQGPPPGPYDPRDPRNQQRHRPDEYPRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGB1</accession>
    <name>A0ABR3ZGB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding proteins Bright/BRCAA1/RBP1 and proteins containing BRIGHT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">STB3</name>
        <name evidence="2" type="ORF">Sste5346_002820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018818">
        <property type="entry name" value="Stb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164:SF1">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10330">
        <property type="entry name" value="Stb3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="408" mass="41903" checksum="53CD1AE69E8F3FAE" modified="2025-10-08" version="1">MAAATERGIQATSPRDTFTGVAARSVPVTRTHPHPLPTPPNSISPALPPHGLKAQLQKAAKLEPIDSDLDLHDLSDDYGAATTANRGGVAALAAAAAAAQASSGIGSPPLDSSDAISPAMLAKFHLPEILLNHGPLAIRYIIGHLTASVPGFSFIPPAKSRRLVVAALEGRGNGADGGMGGLEGDVEFQKVSWGVWGARRVGGGARQLAPPPTAHGSLGIPIAGGNGGGSGGGLGVDRLRQHTEGSGALYRTADLKNNNNSRNMNVAEDEADRMSMDDDEDGPASASCSEAPDEDMMMDDDPDDLTDDEDWGAVGAAALRAESYSNSAAAGRFGSPMFMSSRPYGSFSMGKFAGTAGSRTHFSFSASARDTSPQQQTTLAATGFSAFQGASDEQEREAIEGLLRLGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGG1</accession>
    <name>A0ABR3ZGG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Pre-mRNA-splicing factor SYF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">syf2</name>
        <name evidence="11" type="ORF">Sste5346_002674</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">May be part of a spliceosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SYF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="403" mass="44388" checksum="BEE0BDD84B3EC1AE" modified="2025-10-08" version="1">MPPRKRVTRASKKAEAAAEEPASDPMPTQPEVEETAEEEPAPKPKATRASKRGAVKAKTPEPEPEPEPEAEPEAEPEVTQPEPESMEVEPTEEKAGEPVEEVVEKAVEEPAKKPAEESKAPEPEPEEAPATPEPPKQTTVAVHPPPAAPAAATSSAADRMARFKALQARAKSSSDQNLKAAAAETQRLSTDASQLTALRRKVAVTSHKILKAEVEDAGGDFERKRAWDWTAEESERWDKRMKKRAAHRDNAAFQDYTQEAGKVYKKQIRNAASLAAPDLDQYARDKLAAVEKAAAAGTLEIVETADGELIAIDKDGSFFSTAESTSFADNRPSKEAIDRLVNDQKKADEAALRKRRERLAKNGEDADVTYINEKNKHFNQKLARFYDKYTTEIRESFERGTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGN8</accession>
    <name>A0ABR3ZGN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="4">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="184" mass="20835" checksum="DCFB3CD3ADA2A3DF" modified="2025-10-08" version="1">MATTDADKAAVASDVADCTSYAFVYGTLMAPEVFFTVCFRLSRPPPALVREYDFRNAVLPGYTRHRVKNQEYPGIVPDETEGASVRGILIGGVTPANQHHLDIFEGSEYERRTVDAVLDEAEGADGEKTESAEKTEKKTVKAQVYVFKYPDDLERREWDFDEFCREKMHKWARADYTFEGESGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHQ2</accession>
    <name>A0ABR3ZHQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046741506" description="Small secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11548" checksum="D40E54824A185817" modified="2025-10-08" version="1">MKSTLIVLAAAAATFPSAFTAMAAKPKLNQYANLDDCNNDRNILFHAAPVSGRCYNLDGRTGAFFWATGGMLNPRVYSGTNCNGVEDPLSTNGRCIAKGSYQSFKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI91</accession>
    <name>A0ABR3ZI91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="41027" checksum="ADD5712C463F561F" modified="2025-10-08" version="1">MSDMHVAAMGLSVLKRSMGSNYGSPDTPDTPQGPTYNLPPLTWGLVAIITLIFLPAYLWTSYSIKSVYTTLAIVENPNPAAYEAVASDDNDAAPAAVPSAGDAAADEEAAAHAVGANKPITASIRRTYKLLRAANGWRGNFRGFWVAVLIFILAAIGTLVLSAIPFVPGFVAGLIVSLGLVQLQTAWVHTVIRATPATVPVWRRLPPFRRTFEATSIPTFIHWAANVIPTVVSMLLTHVLKLDKYDIRYPSDVPAYSHDMIWKTIVVLVVALVLVFGLTIPANVILVRVQASLLPPDEDTVVPFDRSFNGTVEPAVVGGRSFVTIRNAFRTFSRASWKRVYLLYIKFHVLSIVLNVVYLAIVVPVVVLTSQKVDPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIE0</accession>
    <name>A0ABR3ZIE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002686</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine/threonine-protein kinase haspin C-terminal" evidence="10">
        <location>
            <begin position="424"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="614"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="627" mass="70447" checksum="6FD1F40D545114A7" modified="2025-10-08" version="1">MSRTSTTRSYGGRRTTTGTTAGGRTKPMLFQTELPVSPTDRRRRQPFTRTTIDIVDVDDLTEQLTFVSLDDALTLDNFDGFEPTKEVVIELEDAKVSRTEEIPIREKETTTKPILVEEPPEEGTKQVEDAPEEKSEGSAAPEVAPLGTPTGVLPDDSSLDESYYHEDSIDSGLRVLTWADMCPPGDRIEKIAEASYAEVYRVTNERGTSIIKAIRLASPIKAQTKAQVRSGLVDEEPHDEEDLRGELTISEWLADIPGFVVYKERYIVRGKAPKDLLETHQTFHRRAKRQDPDRLQFYPSPSRYLEDTRFLVIELGDAGKALEDMTLDSVWQLWDVFLHVAIALARAEDQINFEHRDLHEGNLCVRQVSAPKTRDNNNKDGDSPVVFGFSGLDITILDYGLSRGEDMDDDERTEPIAFDLEKDLSLFTSTHAEQCKVYRQMRSHLLKGDRVHLPPDCHCTPYDKGPDGEPISWKEYHPYTNVLWLAYLYGYLVRNFCGEKNELAAFRRATRELWMHMSPDAPPSVLSFPSATDIVHFAVEAGWLTEAQLVGGSNGTGDVSFYSRHDRTVCSTVDVSLLLSEGVAVAAAAADESACSESIIEAQIVDRDEMGPRRSPRRRRPAVRYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIM5</accession>
    <name>A0ABR3ZIM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002772</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="561"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="80"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="591" mass="61511" checksum="3E3A5603DE4C2388" modified="2025-10-08" version="1">MPDGASAQPSASTSASERTPLLSNSNGNGSSNGVSTTPKYATNGDAEAPASNDDLEDATTSPDDEQVVVVQETQTRIFLILGTVYVGVFVGAADASVIATLSAPIASEFRSLSLLSWLAASYLVANAACQPVSGRITDVVGRGPGLVFSNIFFAIGNLICGSAHSANSMLVGRVVAGIGGGGLMAISTFLGSDLVPLRQRGVAQGIGNIAYGTGAMLGGVLGGATEHIWQDRWYGGWRLAFYSQVPVSVISAILVFFLVRVPPHQAADDVGLGTSNSAWSQLSRIDFPGAGLLVTFLVTLLLGLSAGGNIVPWTHPLVIASLPLALAAFAAFVLWEANYAHHPIIPVRLVVSRTVLAACIANLVCTAAMLTAVFYVPLYLQVRGYSAAEAGLRLLSSPFGVSITSVGSGLIMRQTGRYVGLGIMALLVFVGGYALAAFGLSSANSAGWFPFVSLFFIGGGYGAMLTITLLACIASVAQSRQAVITSATYAFRSVGGTLGLTLASAVYQNILRSQLWERFGDLPGAAEEIARIRDDLGELKHLPEGWYDGVIASYMDAFRGVWLMGLGLGVVGLISVSLMKQHTLHSTLARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ00</accession>
    <name>A0ABR3ZJ00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17003">
        <property type="entry name" value="CID_Rtt103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047883">
        <property type="entry name" value="Rtt103-like_CID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF0">
        <property type="entry name" value="CID DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="47719" checksum="ED7A1C10E36A584C" modified="2025-10-08" version="1">MAYTDDAVLAKLSALNETHDSIATAAQWIMFHRRHAERTVQLWFQRLKDSPSPKRLNLVYLANEVTQQSKARHKEDFVLAFAPVIAEAIAAAYKGAPSEVQTKLRRVVEVWRERNIFEQPIQAAVESRIEELDKAKGASRTAIGGSIFGNSSSSSSSAAALPQEFVPLVAPQRSVTKLLISTQGAASKADSEYEKIMNNPPPAAPVYAARLNGLLKTIADGEDAVAQMVRARTDLKTVLDNLQAQYQKLLEADQQRLAQLAQRRVEVDERKRQVEDKIMRDLSGNSGGNGDGNRNGTDSVSPGGHSGAGSISPIQEPPRPEVEALTPPSNDPDDMGEPVFPGLDLPQISRSESRDIASESGAASNGNGSGNSVSPAPPQVQVTPASDPSVSGIDILSHLASQAVPVSANGVNKRRRVDSSEEVPNLDDGIDADVTEMLRKESQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK09</accession>
    <name>A0ABR3ZK09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="264" mass="30425" checksum="0DDE13BA066DCBA7" modified="2025-10-08" version="1">MTNAPAYDRDRVVAAVREFYAFLTRIPRWTAGDFQDAPSCGWPELTDEVLSPLGKDETVRDLLRHLPYLMPSRDSEANADDGKNQDHLWGAGTCGDKSMIAPETHTNDYPNTQTLHMLARPGMKGLFEPAGAGVLPPHVAVLTTGSRYGSWLLVDTQLGTATDFIMMERPERDIPAQGSDDYWRAYRTLPVEEMLEEWKAKFIQLEWVVVPDNHMDGVMYWMDARTDRVREIYRKHGWPNSFRKEDCRRALTQWYIDDQQQSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKA5</accession>
    <name>A0ABR3ZKA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="183" mass="19537" checksum="855C32627C65CC2E" modified="2025-10-08" version="1">MPDYTKIAEQAEASLNTHQAKTGGGRVQADDDAAVNSRAVKDFPGSTVQTGDELSTNRGYDCRIPPNEGGDLDAEGRQTRGQHFEGRGGPHEKDQEFYREQGGANDNDMASGRFTASSQRAAQSGDLAEFGRAAAQDNAPSTGRTQFKGSEYYTPESVQDSISAEGNLPPGSVTQTSRKSEFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKU4</accession>
    <name>A0ABR3ZKU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GABA-specific high-affinity permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UGA4</name>
        <name evidence="8" type="ORF">Sste5346_002122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF6">
        <property type="entry name" value="GABA-SPECIFIC PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="59546" checksum="BEB47223C87E9DF2" modified="2025-10-08" version="1">MPSLDVEAPVDPKLAAATTSADGVNLASAADAELLAQLGYKQELKRNFSTLEVFGIAFSIMGILPSIASTLAFSLPSGPGGMVWSWFIASGCIFVVGLAMADLGSAMPTSGGLYYWTHYYASPRTRNYLSFLVGYSNSLGLIGGLCSIDYGCALMFCSLIVIARDGEWEASNGIVYVVFLAIVLTHGLLASTMNRIMNKLQTFAVFMNIALTLATIIALPVGMKNARNDGKFIFGTLENLTTWPKGWTFMLAWLSPIWTIGSFDACVHMSEEASNAAKAVPLGILSSIGMCWLLGFVLVIVIAACIDPNIENVLGSVYGQPMAQIYYDALGKKGTLGFMSFLFIVQYLMGLSILVAASRQAWAFSRDGALPFSNFLRKISKTFGYIPVRTIWGCVFVAVILGLLCLIAPAAASALFSLAVAGNNLAWGTPVFARIVWGNARFQPGAFYTGRYSKAIGWFCIVFLLYGIVLSMFPSSGPNPDPQSMNYTVVINMAVWGGASLYYLVDARKWFKGPKMTLGDGEEGGVIGEITEIAGVGVPTASADSEDTPTDKEKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL54</accession>
    <name>A0ABR3ZL54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611:SF2">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="83"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="704" mass="78516" checksum="F7A754212BAE997C" modified="2025-10-08" version="1">MERRSTVHFDDEEPAPNEAPKPSTPVEAKSLNNTKMSAHGSNRSASQSSTREVTTPEATTKPTQSSLKVYNTKELTAVDKKWGRLFEMDNQPTERFREVMHSLSRYIIGAFPSSENIVLVPAKLASFYNFHSVDSDPFCYKLIFQSGERDLNRRVAELYQDLGCSYHLVQASPGLQPRVPGLTPDGFTRWMALHLQAFPDGVSQRLDRVISDFPLDAVSPLDGRTERLPKQLSRYLLPRVPDGRIRSLLQQAVKRHFGESALLAFSFPDEKSGRPAPYTSQSCPSSPSSRSLPLPSSPSASTPTVFQAGYRDSHGHRASDPGTVSHTSEEKVVPPTHRRHASYPGSQSGSRRSSSELLHDRRESREYDRDREREREDRRHRSPSRPRSSRHQSSSRHDSPAVAASTERKEEVVRRSHSSRQHSLRGEEKHHHRSESHDSRRRSSSRSSYADLPTRSSSCLVTGSSNTSSSSSSSSRNKYPPSPLSTVHPSSRSRSRSTTPASRDGSRPPATAATATNTSARRAPSPKIHHSARASLPEIHYTDRRWQSSVMRDGDRDLARDAMEHSAEINRRASYYGPPPALAMAEEEARRAKAREHGPGHRMKRRASSGEEQNYRLYGSPVSRESEAKPVVHTQIKTDVSSTPRSSSSSSPRVYPTRPPVSLAATVTSLEDEQARLVNEDEGTQSDQTWEDYLQANPRVASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH0</accession>
    <name>A0ABR3ZLH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="671"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="705"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="773"/>
            <end position="822"/>
        </location>
    </feature>
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        <location>
            <begin position="836"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="878"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
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        <location>
            <begin position="942"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1098" mass="113934" checksum="A61A4FA0FEC3D5B1" modified="2025-10-08" version="1">MSSIIQNLVVDGSTSRLPPKTNDDNKNNNDNNNTTPSKDAQNDKRKTRRGGVTKRLKLKKIKAGKKKLEADHKEALATLNGGLNKLHGQTRLAVLATLSTIEADKARLDADAERIKAQADADRQANADRMSSSSSSSSSSPQSSPQLPVPAYNPHATTVCPLSTPVHVPTSPAFMFNPLVPTFTPSPSPSPSPFLSPAKIPTLAKAPAGSSTKVQPTAQPKDQPKVQPKVQSKVQPEVQTKTPAPTPAKTLAKSLVKVTAKASVEAPANTPANTSAKTQPKAQTKAQTKAQTKAAKAQARALARAQVEDLAKALVEAVATALAETPAKVPVEAPAESVKAQPKTPKTPKAQPRTPVEALDKAPVKAAVEAPVEASAKTPVKAQAEAQPTTQPTAQAKSYSKAHLVAVPLVPLPPRVPLKAQPKTQPEAQTETPAEILTTVPAKTQIKTPTPAPTLTPTQTPMIPEPTTAPAPPTEPFSFQRRWPSLSSRPPSPTPSMVSIYTSVSSALTARTRSSPPLSSRHLLHHVRRRPPRPKPIVATSIPPYSFESELGNATVCPPPPPTSFTVCLPPNPCGRPRLNVVISHKGTVAPVTHLASSPAVPAEPCITWATPVAWDSDASPLKRSASFSDFETLTAKVEVPARRAVDDIDVPLASTMTTMTMSAKTFGKLPESASASPVSSPSVSHRGSVSSASSNIHSPGSATSLRLASRAPLPASRPLSSSPSPRSASPVVSRPASASPSPSPSPSSRRPSSRRSSASASASVSDIPSFLRPTSSSASRTRSVSVSSSASSVSSYKSSKSSKSTDPASSFSLRRSSLANGDGDGKGKGNGNGGLASQSSRLSRSFPSVSRPSSRVPPSARPRVSSPLASPPASRRNSIVTGITSRGNRQANANASASAIATPAALSGIAILHKAQLAEAEAERSQAKGVGKGKEKEKSPELSSSTPSHSSSRSLSRLSSRLSSRSSSPTPPLGPRTSPIAIPAMSIPAVDTPVRIPRAPFSRTSSTSSNISESSVSSSELPSAAPSSPDVFPQMSPEMAPLDDLDLSVSTSVSVSPPPRLPTLVLPSPLSLSPVPSFSSLHPLHKPIPVPPNTPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMM2</accession>
    <name>A0ABR3ZMM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF5">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23685" checksum="391E92DD47C464D3" modified="2025-10-08" version="1">MAAVAIDPPTGSSSSSTSSSSSHPSSSSSSSQPTMASIPPQPPSAGLPLPTRNPLPLSASQEAQVRDMYYERVRKQCSEEIKAFADCALGRTFSVVFKCREKNNEMNACLKSHATPRALDEAREEWFSKRAERAAERAVKAARKAEQEKLLREWWGLQDADGSKEGYEDIQAKRRKYEEARQHRPERFGGMPAKDRPRFDDVPVVVEDETKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN32</accession>
    <name>A0ABR3ZN32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cystathionine gamma-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF35">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE (AFU_ORTHOLOGUE AFUA_7G01590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="46796" checksum="0930D86E16BABCD3" modified="2025-10-08" version="1">MVAAKKGPDGLAATFEPHTLSRATRAVHADDYVNSHRAVAPPLHVSTTFRYNDDPDALRAWDNTNPEAPFDSHVYSRDSAPNTTRLEAILSDLIGQPTLTYASGMASFHALVVFLNPRRVAIGAGYHGCHGVLDVMKKLNGLEKLDLMKDEDLAKLQPGDIVHVETPLNPTGEARDLAYYSKIAKDKKCYLTVDATFAPPPLLDPFQWGADIVMHSGSKYFGGHSDILCGVLSVNKKYIKDPTSRDAEQNWLAGLQYERLVIGGVMGSLEGWLGVRSLRTLELRVERQSSNASKLVAWLAAEQKNPESIVSQVVERIHHASLQPEAADPASWLNQQMPRGFGPVFSIVLREEAQARRLPSKLALFHHATSLGGVESLIEWRAMTDPHVDKRLLRVSIGVEGWEDIKADFERAFADLVAEKAATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNA8</accession>
    <name>A0ABR3ZNA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035213">
        <property type="entry name" value="DUF5321"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17254">
        <property type="entry name" value="DUF5321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="205" mass="22769" checksum="1C218E968D625D4B" modified="2025-10-08" version="1">MNAATIRSLRAAAVRRNIATNPRLMSFAVQRQSYSSLPTIAQSSFWKQLVPKPLRRGKDGKLPVANAITNARKAKEWNPATFYIFAFLFIGSMSIQMIAIKKDFDTFMRQSEVKIGLLKDVIERIQKGENVDVESALGTGDPVKEAEWDSVLKEIESDDVTRELRRQEKKAAEAASTRSAGPETSQQNTPSGPSNTKIASTANFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNU9</accession>
    <name>A0ABR3ZNU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="13964" checksum="1335CB82A2F1F054" modified="2025-10-08" version="1">MCRTAYYAHPLCGCRWYAVTHPCGPGMGFRTCSRFFTGIAQKDDVGFGTGALQFSWKELFVGRNYDKERRVEETWSTVPCPLHTLGGVYDRNYVRRILDSKNGMRVGLGPDPQDLGLECGCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNX8</accession>
    <name>A0ABR3ZNX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046813492" description="Mannan endo-1,6-alpha-mannosidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="475" mass="51111" checksum="50CBE92C472FFA52" modified="2025-10-08" version="1">MAPSFLKSLLVAAACATTATAQIDVDLTSSSSVKNAMATIAYNLLSYYKGNLSGNTPGILPGPPPNGDYYWWEGGAMWGTMVDYWYYTADTSYNPTTLYSLVFQAGPPGNSYEPANWTASLGNDDQGFWGMSAMLAAEVNFENPPDTDPQWLALAQAVFNTQAARWDTQYCNGGLRWQIPLTNNGYDYKNSIANGIFFNLGARLARYTGNDSYAQWAETAYNWTADVGYIDAAYNIYDGAHVEHNCTDINKAQFSYVAAAFIQGAGFMYNYTNGSALWEQRLTSLTNRTLEVFFPNGIAVELACELTASIQCTADMLSYKCYLHRWLAQVTQVAPFIKDTILPVLKTSAEAAVKNCNADGTCGFRWTTSSYDGDTGAGQEMNALGALMSVMITLEPLKAALTNTTGGTSVGNAAAGVGSSITTTNYGPITAGDRAGASILTIIIISGIVSMMVWMNTGEGEGFRLGLFGKGKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP36</accession>
    <name>A0ABR3ZP36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001627</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="363"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="647"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="656"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="792" mass="86635" checksum="A3F01E85B022AB75" modified="2025-10-08" version="1">MSSVPTDSTKAKPASLSDGSPTNSASDSAVSVAGTKRSRTDMELGDLAAAEALSISNNGDSKSQHKKDKTREKKEKHSKHSDGKATEGAFGEDDGGEWQTIRGGRPTKKLKKVPKKDSGNYPALNFNKNARLQSKIQVSDLRNLVTYIFADGTAPQWIGVHHRPSFRKIVTILVPGLEEAMFKTGVDFAQWMEQDDGSIAALQLWTKNIATPHDDAYPRTLDKDNLPVAVQPFADVFTQLWPVRARGNEKYATLFSPVATFLTAPLPKAASSDDNSSRPKGSGPRFRPDNGSKDVRTRITEFIATPEEYLANEFVLHPALLPADQRAAFEDEPGWVHTDVANLKDGEVPEADIEQGSVTAGRKVFAIDCEMCKAADDKFVLTRISVVAWDGEVVMDELVKPDEPIVDYLTQFSGITEAMLAPVTTRLVDIQRRLLAILDKHAILVGHSLDSDVRAMQLTHPFIVDTSIVFPHPMAPAKKHALRWLSSKYLNREIQKGHGTARGHDSVEDARTCLDLIKRKCEKGKAWGGSASGQNAEWAGGEGAGENLFHRLARAGTAYRSQGGPQATGGVATGKSTAAVDWGDARRTLCGEASIVLGGCRSDTDVENNLMRAVQGDPDGKVVPGGGVDFVWARMRELEALQGWWNRNKLSGGADPQPNQNQTQNQNGHGPPTLQMLEMLMAAEEDKHPDEDKPEDDSEVSPLERAVRILARRIRRIHSQLPPCTALVVLSGSGDPRAMSRLQAQRAQHKKEYHTPGIKWDQISVPWTDTEAQQLQQAVRRAREGIAFVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPI7</accession>
    <name>A0ABR3ZPI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase III subunit RPC9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001834</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC9 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038846">
        <property type="entry name" value="RPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561">
        <property type="entry name" value="CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="7">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="146" mass="16645" checksum="50D3C628D6B8B584" modified="2025-10-08" version="1">MKILEAQNALLSNFEVYQFLAERQERLGKQKQNRRRGPGNLETLVHELLQYFRSPPGPLSQQPVTYTSEAVTTLVERLRGYDLAKGELLMILNMRPQMPAHLHACVEEVESRLTEQQQLEILDIVAEVLGAFPVVEGAEEEMEDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPR0</accession>
    <name>A0ABR3ZPR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan 1, 4-alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="812"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="945" mass="98835" checksum="E945CC0A8F2D0533" modified="2025-10-08" version="1">MDDPWGSPWTSSAEHNQNGSSGNGNENGTANGNGGTPKPPQPALLAGGLSGNTPFASLPESSPWADDDDGGFGGFDDDNAFGDWTAADTHGGSLGGGGTTTPGSNGWGAFAETDGFGVDSGFGSGSNQHLSPQRKDKSTTYGGLGQLSPIAWPSSAALSPAGSPGGAGSPRRRRALSRRSSVNSLGSSRNGSRNGSLSGFARSPSVDPWSTAPMATEKRDDLGLLPGTTRARASSTLSIPILRLDDSSAGKGLEEEPQSMDDKTVTATPTVETAPPDLPEIVAEHVDSEDSEESTDNDDDEENGDTPKPPPQPTFPSIPPPSSSSRPSTAGSDGSRNHHHVDIDDPQQDSPTTSIEDDKGTTTSCTTAAATATATTTPQPHVVQRKSSSKVQGLVELYDGLAARPTATRSLSASSSTRDSSRHGSIVSDRSIDTTESPENEAAETTPKTTLAVGVPEPVPGSPASESALPTPKIGLKQEDELPEDKTKGDTEDDGEDDSEEASPEDSSEADHEETVAIPEAISEESKETSADEPLQATEVDTKVPTKEEESHKAPSTNKDADTDVLSASRLLALFGKQTYTLDQAKVDELYNDKDVKVKPRSKKKKDDGEEPLVLDAFIPDYILDDSFTAISERKVWYRIARHGSYRKHAAGGDDNENYRPVTWRTSAIRDDTVKIVRRWMEEDSFTGKPTLGGGFGRGLGGAGGGGNRSGNLFGWDSAAEPVALDEIFKRKKPSTTTGGGHKYNLSSASSAWANEGSGASADSPAGFSPGFSPAPVFGWGSNSNTQSHDHLPAKPESTRNSVQFERPMPSPVVAVPSPTTTQPSRFSVVLPPRDLAPTLPPSTAKEDTGAFADGDDDDDWGEMISSPVKEEFSIPPLSAPLSLPPAPSPVQAAPAFVAPPPKSHSPAPAPVLAPAPTPQLDERRLAELADSIISGLPDLSYMTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ62</accession>
    <name>A0ABR3ZQ62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP dependent RNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="722"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="980"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="250"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="404"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1536" mass="170342" checksum="D40A34379BA5F5AB" modified="2025-10-08" version="1">MAGNKKKKKPAASTARGFATTSIASKPRLDPVEGAADATAAAPQTAAKGKDGAQAPAATQSQNAKSTTAENASTGDGKATAAPMLSPEEFEKQLEESELQLLVEKYAPKVRRDAARQLTRLETDRRILRGQAESVNSKKWIPQDLMDQILDLIQSESRFAASNVAAEASSSGKLLPEEDLTIKLWTLEQALESAGFPDSKVQSVLKYVLDISTQVGPGPKDSIWGLEEALEWLARESSADELPDYVKQGLQGKKSSDADTPLASGATTPSLLEAEVGQKKRGKSNAANQSPKGNSSKQSVITYNGDIEPEDLGPMYLDTKARLFTLQRPLQVDTPKGRPNNKPAPVVVLSEADKLETAKLLGKLERIENDILFDRKLAEMQWRSKKIILEREFSEATRKAAEEERAKAKAKEEAAAALRDDSSDSSDSSDDDDSDDEVSKEAKRVAAEILAQDNSDDDAIADLFASLPVSEVDPSTGKTNTVVNSPDGSKVIIRDFGKWTGVSPVRALEEACRARDSSVRISYQLVSDISFANRHMVSIAWTKPQEIPVLTPLPELDVGMSSTRFVFKMAKVATPDAKQSEAFIATTALFFIFGASAKEEKVAMRLPHAWRDLWSEFAEAKKNLADSLDREAIKKLRNLVRQRRDQELEDGVVLQGAFRGRTAGRNAADSGEDSGIERGGRAVNGPEYYQRIWHDKSSTPKYQAMLQSRMQLPMWQFRDRVLETVDREQVVIVCGETGCGKSTQVPSFLLEHQLAQGKQCKIYCTEPRRISAISLARRVSEELGEGRNDLGTPRSLVGFSIRLEANTSKETRLVFATTGIVMRMLEGSNDLREITHLVLDEVHERSIDSDFLLIVLKKLLTRRKDLKVVLMSATVDAERFSKYLGGAPVLNVPGRTFPVQVQYLEDAVELTGYSNDNRVQEKQIDLDDDLVDEVVETSSKPELLKSLKSYSNRTRNTLAQMDEYQIPFDLIVQLISNIATGEQYYKYSQAILVFLPGIAEIRALNDLLLGDKAFASNWLIYPLHSSIASEEQEAAFLIPPPGYRKIVLATNIAETGITIPDVTCVIDTGKHREMRFDERRQLSRLIDTFISKANAKQRRGRAGRVQEGLCFHLFTKYRHDQILSDQQTPEMLRLSLQDLAIRVKMCKIGAIQETLGQALDPPSEKNIRRAIDALVDVRALTASEELTPLGIQLARLPLDVFLGKLVLMGTVFKCLDMTITVAAILSSKSPFTAPFGQRQQADTVRLGFRRGDSDLLTVYNAYLAWKRVCQSAVSAAGGGEFQFCKKNFLSIQTLTNIEDLKGQLMVSLVDSGFLPLTDEERRNLNKLRYSSSGRGGRRRQQAFFELPQRVNINSDVDIISQSVIAWSFYPRLLVRDGNGLRNIGNNQSIRLHPSSVNRGHNELRWLSYYNIMQSKSMYNAHETTAVESFPIALLCGDVRCDMFSGVLILDGNRARFAVPDWKTMLVIKVLRSRLREMLSRSFKAPGKQPTAQHQKWFDVWQRIFTQDFGSDSSTASASASVVVNNNGVGNNHGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQH2</accession>
    <name>A0ABR3ZQH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Glutaryl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_001329</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="12">
        <location>
            <begin position="47"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="11">
        <location>
            <begin position="162"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="10">
        <location>
            <begin position="284"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="47565" checksum="3570E926A63052D0" modified="2025-10-08" version="1">MSRHICRRLGGQLLRQNTPAVSRRAYSTPAATTFDWTDPLSSKSLLTEDERAISETAERYCQEQLLPRLEEAYRNESYDKTQLEEMGQLGLLGATIKGYGCAGVSTVAGGLITKAVERVDSGYRSGMSVQSSLVMGGINEFGNEEQKERFLPGMAQGKILGAFGLTEPNHGSDPGSLETVAVEHPTKKGYYNLSGSKTWITNSPIADVMLIWAKVADPSKGLAKDGTPKKVIRGFLVERKDAPAGTLETPAIKNKLGLRASITGMIHLDNCPVPAENMLPHAEGLRGPFGCLNQARYGIAMGVMGALEDCISRARTYALERKQFRGNPLARYQLIQKKLADAATDAAFGTLAAIQVGRIKDAGGDAAVGLPDMISMIKRQNCDKALQGARTLQEIFGGNAVSDEYGIGRHVANLFVAQTYEGQSDIHSLIIGRAITGVQAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQL9</accession>
    <name>A0ABR3ZQL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOP1</name>
        <name evidence="10" type="ORF">Sste5346_000679</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00659">
        <property type="entry name" value="Topo_IB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03488">
        <property type="entry name" value="Topoisomer_IB_N_htopoI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048045">
        <property type="entry name" value="Topoisomer_I_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="9">
        <location>
            <begin position="441"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="222"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="923" mass="104309" checksum="9B2E8B54C050CD2D" modified="2025-10-08" version="1">MSDSSDDDRPLAASNGHVSAARIPKSEDIAMDNYSPNVRMAPAGVSIRHGPVTGANGLAKRKSRASIEQSVRYKDESDSDDDAPMAKRQKSKYVESDSEDEPIVSKKHSKLPISINDTPLLNSGSDKKPLDVRLADKKAKIEQAANSESKALLANGSNKAKRPSNGMSASKRPQSDDSEDEVLSKPKKRQSNGATPASKKTNGIKVKDESDSDVPMAKKKTPTTSKTAARPTAKPATNGKKAAAATPKKAATSKAVKKAESAEPGDEEEEEEEYRWWDAPKKEDDSIKWTTLEHAGVVFPPAYQALPKHVRLYYDGVALDLHPDAEEVATFFGSMLHLTVNTENPTFKKNFFADFQDILKQTGGARGPDGQKIPIKDFAKLDFKPMFEYYKAQSEARKNRTKEEKKVEKEEKAKLEGPYLYCKWDGRKEKVGNFRVEPPGLFRGRGEHPKTGRVKKRVMPEQVTINIGKDAPVPKPPAGHKWKAVQHDNKATWLAMWQENINGAYKYVMLAANSAVKGQADFKKFEKARALKKYIGRVRADYTRELKSEVMADRQRATAMYLIDRFALRAGNEKDTDNEADTVGCCSLKYEHITLREPNTVIFDFLGKDSIPFYDEVTVDRQVFKNLKMFKKPPKEDGDDIFDRLNTSQLNKHLSSYMQGLTAKVFRTYNASYTMSKLLQELPVTNVSIAEKVKLYNDCNRKVAILCNHKRTVGASHEAQMEKMGDRIKGLKYQKWRTRMMMLDVDPKLKKKKGAEYFERDPELTEEWVLEHQKFLAEEQRTKVTKKFEKDNEKRAIDGEKPLPEKELKERLKTVAELEAKFKKENRTKKVEAEGKAPAVEKLQAASQKIDERIHNMELQAADKDGNKEVALSTSKINYIDPRLTVVFSEKFGVPIEKFFSKTLREKFNWAIQSVGDDSTWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQN9</accession>
    <name>A0ABR3ZQN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="4 11">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RPO41</name>
        <name evidence="14" type="ORF">Sste5346_001468</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 16">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 11 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="13">
        <location>
            <begin position="422"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="94"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="351"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1430"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1485"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="99"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1485"/>
            <end position="1506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1592" mass="174076" checksum="F5181CDE019249DE" modified="2025-10-08" version="1">MLARPAGCCHAAALRRLPSASTISALPTQPTTRLLRPQSPNLYRPIGVDRRLLTTRSDRPELRSWRPKTFYSGIGYLPERTLATALNDYSPIPLDDHPSPLSSSTSSSVSPSSSTSSSSRYSPLMYSASPSTSSSTSRTAVPTPLPLWELRPHNPHAPLVLQDVEQTHSLRQKINTRGIPGDLDEMLSVLDACLQVGKLDRAALVLKRLSQPGFSTPDVDIVELHNRYLRAVVDQLLVEPDQATAEELHKWYELEMRGKLGQQTPETIAYMLKASLLTAHGARRERLVDRYMGLAPGDAGLEVLYMTGILNDQDRAAITDICRTYNLESFAGDVETTTLFEEALRSIDPEGVAASQEASASASTASRSTSTDTLADTPDAPAVLGTPQKGMGLRMLKQTLSLFSEIPQGRDIASLNVAERREIQSRLERDCVDAAVERWTEENQALLKMGLNTSLTTASLNSRLYEWHRDLELRLSQELKKIEVAETTGSKNKEDLDRCLYGPFLRQSLPNRLAAVTIVSTLSGLAMQGADKGISISNIITQIARVAEEDIRLQQHTKMMAARGQKTSARAAAKTAAKTALRKAMATRPQKGSLQTAGDAKETAAATVAANAANAAENAAATASSSTTTPSKAPMEDRDMAWPITIKAKVGAALLSMLMETAKVTAVKEHPETRTLISQQQPAFSRINQLRRGKKVGMLVANSTLVELMKREPRGDFLARHLPMVVEPQPWQTVDKGGFLEYPAPLVRVKDSRKDQKIYAEAAIARGDMDQVLKGLDVLGRTAWKVNRPVFNVLLEAWNTGEEIADVPPISPNIVVPPEPDSSEDPMKRRTWLKAVKAAENLRSGLHSVRCFMNFQMEIARAFRDQTFYFPHNVDFRGRAYPIPPYFNHMGADHVRGLLTFAKGKALGEDGLRWLKVHLANVFGYDKASLSDRAAFADEHVDKIRDSATNPLKGERWWLQAEDPWQCLAACIELSSALALDDPTQFVSHLPVHQDGTCNGLQHYAALGGDEWGAQQVNLVPGDRPADVYSAVADIVKAGIAEDAANGDPNAKALEGKIKRKVVKQTVMTNVYGVTFAGARKQVLKQLDNLYPTLQADTDIPPLILASYIAAKIFSALSTMFSGAHDIQHWLGETGGRVCRALTPDQIERIINNEPNQIAAANAAKAAKAAAKLKTKSGKPRTEAPSKSMKRENDEIIGQFRSTLVWTTPLQMPVVQPYRKSATKAIETCLQDLILSVPARSDPVNMRKQLQAFPPNFIHSLDASHMLLSALECDALGLQFAAVHDSFWTHAADINTMNRVLRDAFVRIHSEDVVGRLAREFEARYRGSLYLAKVNRSSPVAKKILALRKASPRMSLKDELVLENKRLNLLGSDDPASVAKGRNMVTPGSLFAKAQAATDDADAVVEAEDLSEFSLGSIPKEEERLINASTAAATTTTKKPAGRPKKSASTTEDDSTSRSRITGGMSLDGMGSAMGDVATADEVSFDEMEDESASFDEAELEADAENEAEHNAEDADEVMSAEDVALSGTGHFEAQLRGLKRTGNKYIKTSPAMATKKRSAPIQIWVPLTFPAIPAKGTFDVRRLKDSDYFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR26</accession>
    <name>A0ABR3ZR26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="249" mass="27071" checksum="63C34CF15EF905EC" modified="2025-10-08" version="1">MGRDNVEGPYYFYGSRNMYDIRRPADDPIVPQQAFVDFLNLPATRAALGIDRIPELSTVPTPNTTSSSFVYAAQSEAVYNVFTRAGDYVFPSFLADLEYLLENGIRVLLMHGDADYIANWFGGEAVSLALSYPQSFLFQAMPYTPLVFDDLESPENPDSPGNGNGSVQGKVREYGNLSFAVVYDAGHFLPFDKPALALEMFRRAVANLDLPTGRGPTNNTAVPFAPDSPLSAASADATTRDISTSSPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS69</accession>
    <name>A0ABR3ZS69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000852</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055449">
        <property type="entry name" value="Iec3-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032742">
        <property type="entry name" value="Iec3_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24244">
        <property type="entry name" value="Iec3-like_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14612">
        <property type="entry name" value="Ino80_Iec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit 3 N-terminal" evidence="2">
        <location>
            <begin position="41"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="INO80 complex subunit 3-like middle region" evidence="3">
        <location>
            <begin position="146"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="507" mass="54828" checksum="00BBF6185D99CAE9" modified="2025-10-08" version="1">MDVDSATSIRDVKMEDAAASKSNDGGDSSSKNEAPKTKPYRSWKKKFQKLRVDFDVSIDINEKLHTEETNALQTTKRLAVEIDRILDLLLDINNTPQIPGSKRIDLSLPRSKNTKALDIDAEGGWERRYFDKNDPNAPPPEPPARSLKSLLADVPHLDFAEVAKKNPAQVTDLVATNENKLAFVVPDVRTLKKENRDKTEVDLSHVYPESFLTADDIDNYLWDTDRNIAGRALLAGENPPPMIPTVAPFAHTPDTHIAHVGKGDTAWDELFNRSIVENDLPKMVNTTPFWYLSNTIARNPTSVYSWLKDHAPKAIFLQEGEATAQAAAAAAAEKEREKEKQERDGGDHGSQKGGAAGKGKRQARKSAFGHFHIIGGPKRTPAADAAELSDDLSPARGTPAAARGGKRKRTLEDDTGYRPKGAGGSSALARANKRKRKSESGATGEEDDDVTIADASAVSVTKKRARKSAAVDAAADGDTEVEGDAAEEDAGAGAADTVDREASPVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH3</accession>
    <name>A0ABR3ZSH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein vps5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">vps5</name>
        <name evidence="4" type="ORF">Sste5346_000668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07627">
        <property type="entry name" value="BAR_Vps5p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035803">
        <property type="entry name" value="BAR_Vps5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="179"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="560"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="467"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="585" mass="64059" checksum="2031F9C4233A25A5" modified="2025-10-08" version="1">MDPLEEAPWADTPQSSSTTAKAQDDDATTTSSTAASKPASLTPSSTMSSSGGRPSRITPRRLVAQPTRLQVVEDDPLGPLGSAGSASTEAGGDNAGPGGLESPPVPPSKELSLPMRATMPTTPGGTARGAPDPHYIDEDDTDVSFGRSPRAPPPVAAAHPSPVRTSSRPSISVEQAAKPTFSITVGDPHKVGGATGSHIEYSVKTKTTSKAYKQGEFVVNRRYRDFLWLYNQLHANSPGVVVPPPPEKQAMGRFESNFVESRRAALEKMLNKAAAHPTLQHDGDLKLFLESEAFNVDVKHKERKEPNLGESKGIMSSLGINVGGGVKFVEQDDWFHDRKIYLDALENQLKALLKAMDTMVNQRKAMAEAAGEFASSLHALSTVELSPGLSGPLEALSDLQETIRDVYDRQAQQDVLTFGITIDEYIRLIGSIKQAFSQRQKAFYSWHTADAELQKRKASQDKLLRQGKSQQDRLNQINAEVADAEKKVHQARLLFEDMGRLMRNELDRFEKEKVEDFKSGVETFLESSVEAQKELIEKWETFLMQLDAEDDEALFYRPPVYNASSKPAGDTAVDRARARIDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSQ8</accession>
    <name>A0ABR3ZSQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="3">
        <location>
            <begin position="128"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="608" mass="65857" checksum="046C2193DD27FFA3" modified="2025-10-08" version="1">MSSLLAQASNSRPLQLAATAVVSGAVAVGIVLGVQHNIQASRLRRLKRSVANDVANEERGNGNEASEVIGGETVASKSPSPTNGDHNDLGDIVETEDPEELRALALARRAQAGDYAEEVILEQLTRNQAFLTPEGLQKVLDAVVVVVGCGGVGSHCAAALARSGVARIRLVDFDQVSLSSLNRHAVATLADVGRPKVRVLSRRLLAVAPWVRFDLRGEKFDKDSEARLLGPWKDADVEGASGLSAEDNKERPVSFIVDAIDNIDTKVELLRYCHEHKLPIIASMGAGTKSDPTKVVVGDIGSSAEDRLSRATRRRLKLLGITGGIPAVYSTERTEAGDGKAALLPLSDEQFAKGKDAVRELGALPDFRVRILPVLGTMPAVFGYTLANHILLVLSGYPHDYAAIKGREKLYDQILAAVHGFEEKMVRHFEEASKSVNGDDPKAADEAPAEEDGNKKGKKSKKDKKKATPYDANSAAVGLRVPLTSNDVAFLVEEIYRGRSAVSGLPTRTTLVRWQLPERAEGADIVESLLDRVHPAAQDLEGDVPLQAEQKTAKLHLSDLVCMTREEASRHQDLVLFKGQPLSSLYDEATLERIEAKRHEADEYEKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSS5</accession>
    <name>A0ABR3ZSS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000098</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF16">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045013666" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="26"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="576" mass="62309" checksum="C78D7026D7D4F624" modified="2025-10-08" version="1">MRPVSTSRGSAAAAVLLSAAKAVSATASLSDICSSDYAVAALPLDAVQGVTIDTTSVTTQLVTNFTASSNFYPTSTFDYCNLTFAYSHNGLDNDIVHVQYWLPAPGQFQNRYVSTGGAGWAINSGSQSIPTGVIVGGVGGLTDGGFGSFDNQFSDVALVENGTVNWQATYMFGYQAHHELATIGKQLTRNIYNVSDSSKVYSYYQGCSEGGREGWSQVQRYPDQFDGIAVGAPAFRWAQQQVIHLFGNVIEQTQGYFPSSCELEKIMNLTIESCDPLDGKTDGIVSRSDLCLDNLDLNGMVGTPYSCAAAAGGMQSSATPAQEGNITAEAITLVRAYWAGLHDSDGNLVYYTYQPGSSFDDLDAAYNATSDTWGLSVSGLGGIWVSQFLKKLKADNLPNLNNVTYDTLKEWMVETMNLYGDIMQTTYPDLTDFKAAGGKVIHFHGEQDFSIPTASSVRYWESVRQITFAGQSLKQSTAAMDDFYRLYLVPGAGHCAANSYQPNGPWPQTSLQTVIDWVENGVVPDTLAGTGDIDTLCRWPLRPLWVNDGANFTCVESKSSVESFTYDLSAFRLPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSW3</accession>
    <name>A0ABR3ZSW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001026</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="18968" checksum="D7859C8BA675429C" modified="2025-10-08" version="1">MPRTRDVLDLTLPYIDDNELETLIDQRTQMLVRQLEEEKSASISGGGGGGGHNNSGSGNSRGGRGQISVQFFEKRRRKTWYVMRGEEEVCWESWTVKVTVAEPRTESERAKVRQAMESTLLAAVMKIVTSVNAHKDHIPPITTSESNPFPYQINVNQKDAGWAARMGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTA8</accession>
    <name>A0ABR3ZTA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">OMP decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Uridine 5'-monophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_000030</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="11">
        <location>
            <begin position="39"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="168"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="471" mass="49081" checksum="BC0070384B074C85" modified="2025-10-08" version="1">MAAAQRHPSFVTPFAERAEAAVHPLTAYLYRLMVAKSSNLCLSADVSTARELLLLADRVGPSIVVLKTHYDLVTGWDYNPQTGTGAQLAALARKHGFLLFEDRKFADIGKTVQQQYTAGTARIIDWAHLVTVNMDAGQPAVTALADAAARWRERVHYEVKTSVTVGTPVHESFDDSGSGTPSGVATPSTQHASEFPPHVSATSGAGLTSSSSTSFPSNLFATSAPRSDAEAATGLPAPPRDADGRKGSIVSVTTVTQSFEPVDSPRLPRDGTDGGVNGVSGSANHNDGTKGVDSLSGSGGRSGAAAGSSSATGRGGSYIQDGAGAVYQGIEEAPLDRGILLLAQMSTKGNLMTPAYTQACVDAARAHKTFVVGFIAQETLNTLPDDAFVHLTPGCKLPPPGEDVEEAGANGQVLPGDGMGQQYNTPARLIGICGADIVIVGRGIITAVDPPSEAERYRRKAWKAYLARVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTI4</accession>
    <name>A0ABR3ZTI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="19557" checksum="EB05828A691ED05C" modified="2025-10-08" version="1">MTAEFHLFPALPYEIRTAIWELCLPHRVEKIECLFRYIRWPYIGCTLYAAHMANRRPPAMSRVCRESRTIVLKTGEPYTRFADALASRFPVAPRRWGQYRDEYYIPVDTTAKRIMPYWPTHCHASPTTPHSNVTHAMDDALPPWSGYPLLPPYTDLLGAACVSMTLLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU35</accession>
    <name>A0ABR3ZU35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521:SF0">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="307" mass="33998" checksum="A6EA751E3C79E23E" modified="2025-10-08" version="1">MASSSIPSPDDITVEAFAEYLGRYPEIIAAVSEAKGGKPGQSSLLELDEFRYVTAPATFGGMGGRRRDMNRKDVLKLVEWKLRHGKFRPTLMKLVESNPSQLVQDSIQTAMGKYAGHKFSAKRSVKMLCDLKGIGPATASLLVAAHYPKQTIFFSDEAYAWLAGGPSYNPPSKYNHKEYEDLMDASWQLIQRLPEEYGAQDIEQVAFVIMYDKKNGAAAKKAAKAEKVEKDTKTEVVKGQDTNAEYIKDDATLKRKAEETPPYPIQGIDTKRRKQPLVKPAPKKVTKAAPTEAPASGSVRRSSRLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG47</accession>
    <name>A0ABR3YG47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010422</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000144">
        <property type="protein sequence ID" value="KAL1887133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="564" mass="59808" checksum="1D405017D10ED468" modified="2025-10-08" version="1">MTDKDIGSIHMVEEKSSDVPATPPVAATVTDPTVAIEGKPKEERTTAKAWLCICFLTMSFGAPFWAVPTTAAISSQLLTSLGSAELSAWVIPSVTTAATVTILLFGVTSDLFGRRIFLLLSCVFGAVGYIVCARATTTGMLIGGLVLLGCAGGVSGVALIAVPELIANKHRHIGVVLVDAVVYIFIVIGPVVGRYSIIDEGESERWRYLYWAGMIAQVITFIGLACLYFPPARPRGVSYKAALRGLDWVGGFLFTAGSVPVLVGIVNTTYMSSTDARVLAPLLVGLAMIIAFGVWETFTTVPYPFCPRDIFASHKGREFSVPFCLTFIVVGFFYSCSIIYPTMLIPLPVGAMLLTAFGRKIGHWKWTMLASVVSMVLWGALLALITPYNKGLMIAFVALNQLSYGWAAYLSVTYTQLGVAQENLGISGGLAGTARYAGGAVASAAFSSAINHGIQTRMPQLIPAAAVTAGLPNELVEQVVAAAPGGAAALEAIPGVSDEVVAAVVEAYKWCVANGLRNAAFASLAFGVVGIVLCFFLEDITPKMNDKIEIFLENDALADKNKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGZ6</accession>
    <name>A0ABR3YGZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010237</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000121">
        <property type="protein sequence ID" value="KAL1887414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="39150" checksum="D049EB740B455623" modified="2025-10-08" version="1">MDVWHSVCHGYPRQLQAKTSMPLPLEEELFENMTPGDDAPSGLDGVGITEQMRQGSIMANVVRLHMTYADITQLNRILAHEPHFTFLRDREVQRLSSELRNWLSGLPAHLRNTVENLEAFAAKSRGREFAVLHIIYHHQCQLLYYQYLQWASSTPSEAGPMEEEISRMVARCKAHAEALSALMWTMNTSAGSECLWSPVNGHLLVVASSIHLHSLLFDNDCGNDDDVLSSSRVRRIRQLLEQNFVMLLQFQKYWPTLKASLCRLAVFQRSCYRRGREQNFRMDPWMFDFLTKHDVAMEERGEEGEGGMLPDGVGDTEMMWSWLSDGNANATHDQLLESLTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHA0</accession>
    <name>A0ABR3YHA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ribosome small subunit biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GEP3</name>
        <name evidence="2" type="ORF">Sste5346_010279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000126">
        <property type="protein sequence ID" value="KAL1887340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050896">
        <property type="entry name" value="Mito_lipid_metab_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434:SF1">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="542" mass="60591" checksum="DCE5CFA105C50D89" modified="2025-10-08" version="1">MVCLRSVIDIDSIRETIAESPYKYNHVYHVLDAADFPMSLLPRISSLLGTMPLRSRNRRSQPGKFIGGRRTELSFVITRADLLAPRRDQIDKLMPWIRDTLRDALGRLGRKVRLGNVRCVSARRNWWTPELKEEIWDRGGANWLVGKANVGKSYLVHHVFPKGRMDTADAKKPLLTLKKKDTGHYGLRRDHGHGARLHDAGGDAGFTDMNDDGYLLPPRPQETNYPQMPVVSALPGTTASPIRIPFGNGKGELIDLPGLERTALIDYVEESKRDSLVMKTRMTPEQVTLKGPWQSLLLGGFIRITPRTPDLVFLAYNFTPLDEHKTMTEKAIGIQTQTSDLRVQNISAPGTGGQIALAGSFQLKYDVTKIRAGPITRKDAANIDIERLPYRVVALDILIEGCGWVEVVAQVRTRNLFKYKTVKKPEPIVKKKGSQVDSNGILQSLDLSDPDEAGPEDTAPNASRETEAAQSETQEIEMQWPEIDVYSPGGKFIGSRRPLNAWMLAQPKTSDKKKMRPRPKPSMKGAKKREKAARRATLGSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHF3</accession>
    <name>A0ABR3YHF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_010199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="171" mass="19331" checksum="E6EA31D2D51051C7" modified="2025-10-08" version="1">MIMPGVITPTGNRRTRPAFPNIIVPIADRIQEVRRDAAARGVNFAAYLDKMKLSLDRVRAFRVAEQAEGSIANLKQYIERDRTITGYQLVLKDPPETRPDGTPYESVDMEASFDKNRDIHDRVTCGDLLQAMKDFVNGELKLSTKGNKSQVSHQTAIRVIQECLDRLRVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIJ0</accession>
    <name>A0ABR3YIJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Threonyl/alanyl tRNA synthetase SAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051335">
        <property type="entry name" value="Alanyl-tRNA_Editing_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF2">
        <property type="entry name" value="THREONYL AND ALANYL TRNA SYNTHETASE SECOND ADDITIONAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Threonyl/alanyl tRNA synthetase SAD" evidence="3">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="297" mass="31813" checksum="B845229CBCC1462E" modified="2025-10-08" version="1">MASPSRTELVFHHDAKRYTLPTTVVAVLPFASMASANKALFKQGQQEEAAAEGAPAATRYYAVVTEATVFHAQGGGQPSDVGTITAGEGDSAAAFNVLSARMDAVQAGQVLHFGQFTSGSADNFAVGTTVTQAIDVDKRILYSRLHTAGHVLGAAVRHLVEKEVEGFDELKASHFPDAASCEFRGKIEGTWKDPIQARVAEYISKAMPVEIDWWDAADFRKNGLERLIPQPAAPSSTTSEAPTEKWRIVRIVGAEVYPCGGTHVDTTDLCGETKVTKISRSKGISRVSYALADMGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIX1</accession>
    <name>A0ABR3YIX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF235">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE APDB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="58518" checksum="F816BD3559A97BD0" modified="2025-10-08" version="1">MNSTRPALQLYDGGNSLPVAILGLFVILAVVWLVQRDRRLAHIPGPAWCRLTDYPRLRWAWSDRIHEFHQQLHRQYGDVVRLGPSCVSIGNPKAAQAVYGTGANLPKSDFYKVLQPLAHGRVVQGLFNTQDEALHRALKRPIAGIYSMTNLVSFEPYVDTTIAALLRQLEARAGQTVDLGAWLQFFAFDVMGEITFSRRFGFLDTGADVDSMIHDIYKFFTYGSAVGQMPLLDRLWAKNPLVNRFLPAKNSSVVAFAQARAAEREAVTEKDDDSYNSRDFMSRFLETRRKDPSIPAQFLTAWTTSNVQAGSDTTAILLRAIVHFLLTNPDSLTKLRVELSLARREGRLGVTNGIVSWKESRDLPYLDACIKEAGRLHSPVGLAMERVVTSKAGLEVCGAHLPQGTVVGLNPWVVHRDPRIFGEDADEWNPDRWLRPKDETRAAMERSLLTFGAGHRTCLGKNISYLEIYKLIPTLFAKYDITFETPDEWKLVNHWLVFQQGLNVKIHVRDEMADETITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIZ6</accession>
    <name>A0ABR3YIZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="9">HMG-CoA reductase</shortName>
            <ecNumber evidence="9">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HMG1</name>
        <name evidence="12" type="ORF">Sste5346_009994</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025583">
        <property type="entry name" value="HMG-CoA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13323">
        <property type="entry name" value="HPIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="11">
        <location>
            <begin position="259"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1194"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1197"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1252" mass="133637" checksum="BAFC4D95C9B7B9E0" modified="2025-10-08" version="1">MSTMISSASAFLPARFRGAQPAAQASAPSWLNKKLTPILQLLSSLTSSHPIHTVVIVAVLASSTYMGLLEESIFDATRSVRRADWSSLSEGSRSLRVSSDTAWKWQPWDSSDVPKTADHLALLTFVFPESFSDSAPKTAPLLDSVPIPANISVTSLPSTANPLGSYSQDTSLAFAVNYDDAAQFTSAAREIPLHETTEGSSAQNDDATATRVTEEHGREKKMWIMKAAGAIQSGSSIVRWLQNGWVEFVDLLKNADTLDIIIMVLGYLSMHLTFVSLFLSMRRLGSNFWLGTSVLFSSTFAFLFGLIVTTKLGVPVSMVLLSEGLPFLVVTIGFEKNIALTKAVLSHALERRRNLERPAAAAASSSSSKKSSGAVAKKVTTTSSPSVIQYAIQMAIKEKGYDIVRDYAIEILILVIGAASGVQGGLQQFCFLAAWILFFDCILLFTFYTAILCIKLEINRIKRHVELRRALEDDGVSRRVAENVAQSNDWPRTDGRGEPSTSIFGRQIKSTSVPKFKVLMVTGFVIINVLNLCTLPFRSSDSLSSISSMAGGLGGVVASPPVDPFKVAASGLDTILSSAKEQNRDTVVTILTPIKYELEFPSIHYALPTDGRAGGHGANSATDPLSSDLTYGGVGGRMVDSILKSLEDPVLSKWIIVALALSVALNGYLFNVARWGIKDPNVPDHPIDPRELAQAQKFNDTASATLPMGEYMPPTPIGNKPMTPALTDDEGDLLAMRPLKQREGAPKPSPSQADLQAAKDKAALIQRTPAEMEQMLKDRRAHELTDGELVYLSLRGKIPGYALEKTLKDYTRAVKIRRATIARTKATEELTGLLDESELPFENYNWAQVFGQCCENVVGYMPIPVGVAGPIVIDGKSYFIPMATTEGVLVASTSRGCKAINAGGGAVTVLTADGMTRGPCLSFETVERAGAAKIWLDSEVGQNTMRKAFNSTSRFARLSNMKTALAGTNLYVRFKTTTGDAMGMNMISKGVEHALNVMMSEAGFEDMNIVSLSGNYCIDKKAAAINWIDGRGKSVVAEAIIPGDVVKSVLKTDVDTLVDLNISKNLIGSAMAGAIGGFNAHAANIVAAIYIATGQDPAQVVESANCITIMKNLRGNLQISVSMPSIEVGTLGGGTVLEPQGAMLDMLGVRGPHPTNPGENSRRLARIIAAATLAGELSLCSALAAGHLVRAHMAHNRSAPPTRTTTPAPPTPSGAMTPVTGLTPVVPAGAAGVERSASTAALSPAAVERSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ40</accession>
    <name>A0ABR3YJ40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Capsule polysaccharide biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="33943" checksum="4660738B2F15C2FC" modified="2025-10-08" version="1">MVLKPRPLPPGRKFFFGYVEFHKQFGYIRIGSFKFNWRKVLWWNSPLLLRYSWRRLHCAYDLKSPLRAFLQLLWPFPRKWPIGALPPPPRLLLADGDAVRARYYRDAHVQNGLPLWHRRDTLQSAFYRLYEAICAADEPMVGYTTEYLFFRPEPEWSLDLLADPRTMTTWEDLHDSDSTSFTGSGTGRPWTEEEKAERLAVMARIAVMLEEVFNWRLDLGLRRDGSVIDKGEGLPEPIWTPERCPAWAHETPGLPELLVLSHTWTGERLERGWKPVYNIIIKDASMRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJH1</accession>
    <name>A0ABR3YJH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PCK1</name>
        <name evidence="12" type="ORF">Sste5346_009824</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="591" mass="65335" checksum="C0BB766A77DEB9EC" modified="2025-10-08" version="1">MDPVQRTSSPYVDPTVKGPQSKILSRNPPNFQEKMVTTTVNKTSLHPSGVAPHPEQHTEIEEQLHEQAHIDYDRVAIIPHPSVPALYEDALVYEPGSGISSTGALTAYSGKKTGRSPSDKRIVKEPSSENDIWWGPVNKPMTPDVWKINRERAIDYLNTRSRLYVIDGYAGWDERYRIKVRVVCARAYHALFMRNMLIRPPPEELEHFQPDYTIYNAGSFPANRYTEGMTSGTSVAINFAEKEMVILGTEYAGEMKKGVFTVLFYEMPIKHNVLTLHSSANEGKDGDVTLFFGLSGTGKTTLSADPNRALIGDDEHCWSDKGVFNIEGGCYAKCIGLSAEKEPDIFGAIRFGSVLENVVFDPDTRTVDYDDATLTENTRCAYPIEYIANAKIPCVSNSAPSNIILLTCDARGVLPPISKLDSAQTMFHFISGYTSKMAGTEDGVTEPQATFSSCFAQPFLALHPMRYAQMLADKIEQHKANAWLLNTGWVGAGFAQGGKRCPLKYTRAILDAIHSGELANVEYEVYDVFNLQVPKSCPKVPSELLNPKTAWTAGADSFDTEVRKLGGLFNENFKKYADEATPDVVKAGPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKE1</accession>
    <name>A0ABR3YKE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRM1</name>
        <name evidence="11" type="ORF">Sste5346_009328</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047148">
        <property type="term" value="F:methylamine-glutamate N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="102"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="725" mass="78966" checksum="1BD5D1681EC6CAAF" modified="2025-10-08" version="1">MSAEAQNQSAETANGVAENVVVVDGTRYKTAKEGLARIYVPLSGGDRKERQNGGGGPAVDDHPQQVFYNPIQQFNRDLSVLAIKAYGTATIEKRAEALAEKRKNALNKKRKRREERSQQASGYGEAKTGGTQADEMDIDDERPTKVEKAAEGQDASQAVAELTSREANGTNDTSTEGETKEDAPQTTQPTSAAPQTPPQPPKLRILDALSATGLRALRYAHELPFNVSVTANDLLAAATESIRRNVSLNGLTDKIEVTQSDALAHMYTIVAKDLTSAAEANATPGVKAHEYKNAAPGSRFRPTAKYDVIDLDPYGTGANFFDAAVQSVRSDGGLLCVTCTDAGVWASPSYPEKCYALYGGVPMKGSASHEAGLRIVLHALATSAARYGLTIKPLLSLSIDFYCRVFVTVTRSPASVKFLAGKTMSVYNCDQGCGAWTTQPLLRTHSHPNKKGSGTFFKYTSATGPRAEPRCEHCDTKTHLAGPMYAGPIHDPEFVQRILDDLPSVSTDVYGTTDRIRGMLHTALEEIFEPESKPFPNNADEAPTPLTGDDALAAVDPAPFFFLPTNLAKAVHCSTPGEDPIRGALLRLGYQVTRSHCKPGSLKTDAPWSVLWDIMRAYVRQKAPIKRESIRPNTAAYRLLKIKQEEDVEKEKSAEMDPANLLEMKKGEEPKEDKQDYATNAAGKQEVIVFDEHLGRQLSRSGEKLVRYQINPRENWGPMNRAKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKW1</accession>
    <name>A0ABR3YKW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="477" mass="51927" checksum="684D106D218AFE0F" modified="2025-10-08" version="1">MAAFSLDEAAQLYSTLRHFFEVAVHDILYYRRLYPERAFAAATAFDVPVHQSRHPAVCAWVRAAVEQVIVQIAGGDDNRGISDRPGSEDGLPADNVNAVAVAVHAPFETKAGSAQAHSLPPGAVLEKWVFDVRHLPRGWPGGIEALRRAQKDIETREQQDEERARERRQRRRRQRSPKKEAENSAVKGQEGHEGQEDLEGQEGQEDQEGQEGQGGHESQVGQEDQENQGDLDDQDDQDYQGDQGDQDVQDVQGGGRYDYYDEEEELANAESEAELDDSPSASDNEDDENNGDGDQGDDSSTTNWKDLHEQLRGVLQRLAQAGQQVAALPDGCTFTMAIELGDGDNAGGGAKTRHMDSNWIPEATSRKRQFGGGLSGGAGALTRSIRSVDSAPLFLECWVEESAVKKAAADGASSAKLAITAKTARDVLPPPPTASASTETSYGMNTSFNFDQFIAQDSFAKDKKPPQNNKAKNVSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL36</accession>
    <name>A0ABR3YL36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_009466</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045596135" description="CFEM domain-containing protein" evidence="12">
        <location>
            <begin position="19"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="13">
        <location>
            <begin position="44"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="498"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="501"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="535" mass="53169" checksum="BF6149085CAEA88F" modified="2025-10-08" version="1">MRLSVLALAGVAPSLCAASGVRPRYRAANIVERDALPPLITAAPVLPPHLNIPYRAARRYDLDRRAADSLPACAKPCIESAITDDTTCTLTDFACGCQYTNGLAIESAASECVYSACGIITGFNAWQTLESICATYLYTDAYTVVYTVPTDTDDGSDGTTVAVTFTNGGSRTTATSDNSGGSTTTVTAGAGGSSGGSSGSSGDSSGSSSSSSKGLSKGAIAGIAVGAAGGAVILCAVLFLVYRCTKRNNAPAAVGAGAAASAAAAPSKPEGGALAAAASIPHAPSPMPAGGPPGNPANVSPMSAAAVPVGQSELDGKTSAVATTVATTPTPPLAPPAQSASPVSAETAVTAQTPQLYDQNGVPLDAAAIAAWQAQQQQLYQQQIAQQQYAQQYAQQQYAAQYAAAQQAQQQPYVVQGYSIAPGQAPQPQAVVSPAGYAAAHPSQPVPGVVYQEAPAGIPQSQYPQELSSQVGSNVASPASQHAVPAAVGPSAALPVAPQEVSTVSPVPTAATTATVSAASPETTAAETAHEAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLT6</accession>
    <name>A0ABR3YLT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1889010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047090361" description="FAD-binding domain-containing protein" evidence="6">
        <location>
            <begin position="17"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="443" mass="49017" checksum="A14CBDD9EB2964CB" modified="2025-10-08" version="1">MDIIVIGAGLAGLTVAIALQQAGHKITVLESAPQITYIGAGIQVSSNSSRILRKLGVDKHIEPYVTEPVDLRMMRWQDGKVLVECPLKAPALEEYKSPYWHIHRADLHRGLMARATELGITVQLDSRVQSVEPEVPAVTTKGDIRHTADLIVASDGLHSICREIVLGHKSPPNPTGQMVYRVTLPTRKLAGIPQLEDLITVPRNNHWIGPHATILSYLLEGINEPLINFVFTCDVNMDEGVNTKIGTNEEVRTRFKEWDPRLDAMLAHVDEVLEWRLFTHHEIPNWAHSSNKLVLIGDAAHAMTPYLAQGAAMGIEDAAILGGILAQPDFGTVEQLPQALQLYENLRIKRAARVAEASITSRYFTQMNDGPDQEKRDAWMLANPGIRERHINIRSRKEFLDELFGYNAYEALDEALKTARAGSVTDVKAQVGTSSVSAIPVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMU7</accession>
    <name>A0ABR3YMU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="477" mass="53354" checksum="06BBACA774550B7C" modified="2025-10-08" version="1">MTRYLEEYARSHEYAGSTLEDRILFNSRVKSVKKAEEGLWHVELDGSDNPTTFFRATKVIDASGITAEPDIPDIPKITAFKGIKMHMKDLATSNLNTNAVCNRIAVIGGAKSGADASYSAARAGKTVYWIIRKSGNGPCWYSPAHTSPPFQSPDEPLLSRILFNILASHFVKDTFFVRLLNRTAIGRSIIRFLWHSIEGGFRKRANFDRPDPLGNGFKNLEPDTPLFWANDNTGVEQREDFFDTIAENVKIIRQDIARMDADGVVLVDGTRIVVDTVIYGTGWQQTPRHYDPQTALSLGLPVPCSLGPAATVDRDKWETLEAAADKVVLARFPILADPPPFFKKAPKMTPYRLYQSIVPIHDSSIVFLGRISVINAWRVAEVQSLWAVAALDGRVHAMHSTAAMEKEVAETVVWCRRRYLNKGQLANWFLWDCVSYTDRLLEELGLKSHLGKEGMLSPCRAKSLSGLVDEYRAKHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN23</accession>
    <name>A0ABR3YN23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="762" mass="85454" checksum="565839EFC10B8783" modified="2025-10-08" version="1">MDDTRPDLRCGVCSRVFSRKEHLIRHSRRHTNDKPHTCEHCAKQFARSDTYKRHLEASHPTLAANGGHGRGGGKRQRTVVACDACHYSKVRCTMDQPPCPRCVARGIPCKYVRPSHAVLDRRLDMGQKSVHADHTPPSSVLPDSERVAGPSPNQQHFPAQLLPDHNQGQLPLDPAAPYNAQQDDGSQCLLFPDYGFLRQPTVPMAPISSLTEGYIHGDDSALSAVLSNSDTTRSTHGFDFVPQELSCWLDAPFSVSEQRHIDLLGASSWPSVFCPHDATDHEDVGVTDNDPTQPFAQARRIAAAYENLQNLSNAHLLSRPASPRARHANQQWLDNLSTSEWAEPDRVVLDTFLDLFEQHVADTFECFRAFTIERFTPPELYLAMAAVGGLYCSTAGAVKIATWLCEMARRKLLTKVHATRPIEKTARVPLIKTFIALQLFGYLSGNKRHYELIEVFHFEMLRIVQDSGLWYRNPDVPEEERMRLVHSLYMLECYRVVIIHRPPVFLPVSSSAALSKMPSVMASQASPQDEVLSRHLQSILSASSPGLRIYSVSLSKLTLCALVLATSQAAYHDLPSFAQGENGTMPRSSDTLWQQAFFEHSLHNWRCAHDVVPSANTMILFHAVHLNMHASLLSIQDFAKSRLFQQSQGKGDKPPRRLFRSDDDKRKALWHARQILHLALRMRTEGESHTQTDEDASLSENNSRDACEVQAPHYTHALFFASLCFWCLGASREFQLGQARMARAGSEMAKVFLQLLSLLASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP45</accession>
    <name>A0ABR3YP45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF6314 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008749</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045632">
        <property type="entry name" value="DUF6314"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19834">
        <property type="entry name" value="DUF6314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6314" evidence="6">
        <location>
            <begin position="606"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="770" mass="84077" checksum="950C8ACFCD6422A1" modified="2025-10-08" version="1">MPDRKTVCIIGAGPSGLATAKNLLWDRRSRSKFVVTLVESQPRIGGLWPSSPDDTTGLVHPLMLANQSRHTVQLSGVAWDDDAPTFPRAWQIGAYLEKYFERFCRGPQHSSDLVVELGHKVVKAEPVNGKWRVTRESTDGQGATLVNVFDYLVVASGYFGSPVIPESLQAVVAAGSSRGVPVIHSSAYRDIETLFAGRSSDAKKGKIVVAGGQFSGVEIAATIASHLSSAEHAPGAKADSLPATTVHHIIQQPFWVFPLHTSPAPTSDAPPFLPFDLPSYNIRKRPQPLVDTQGHITVDTARFVHGLFETALGTDQSDVHPALAIKKDSPVRDAPPMMAVSDTYLEHVRSGRISLSTGKLADVKEAQATITAASGSETVDDVAAVILATGFSAATSLSFFPDSVKQALHFDAADPRQNVALAFNGTCHPAVPNLAFVGFYRSPYWGVMEMQARLATALFVSDAASPSQDASSWIPSTPEWPQLAAALDADHSIERSLALRADPEHTSQFPMGDYLYLMHTFGEALGIPRRTADPDDSAVQTADVVMDVVTPAHYFDGDGDQGDENTGGEPTVDSQDNAWAIENTRLTVKAGLHDARFVARAVFRSLQGTWKLDRTLTSRLPSHPSGRFVGTAEFRLRQGTKDGLSETEKKAEVDEYLYVEDGTFTALNGPSFRATRRYVWRYNHDDDKLSVWFARTDDASKADYLFHGLEFMPSLIRQGWKATAGHLCIDDFYDVHYEFGVKGVNLTNWTLEYAVRGPKKDYTIAGTYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP75</accession>
    <name>A0ABR3YP75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="313" mass="32125" checksum="0A93F1A484B866C8" modified="2025-10-08" version="1">MASVASAKASSGSKAATGNPNPTSAQYAAQRGSVDMLMRTKDKDARLPPTSTADGITRGGEASSSVSTSAAVKPPASAPKMSFLEAVRTQRQVRVQQLRNAPKSSGTTTGSVLAAASAASADPSNFHKGSGGGGFSALATSSSSKAPKKAKAKAKPQAQSNTDWVAALASPSTSAAETKTPTPMQTTTTPTTGQSYTQVESELEADFQKYSRANPLGGVGTSRGGGNSEGDKQKKGQNQGQGQGQGQRTDVPMTASARNLKARQLMVAPQSASRREDERIAAMKKKQYNNGGDDSSDEDVGRSALGRKKARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG7</accession>
    <name>A0ABR3YPG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF10">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="432" mass="49189" checksum="D67C41A229C3AC4B" modified="2025-10-08" version="1" fragment="single">METFLENIPQPGQLSELYASLFSRYTANDPENQMLAAMALEILAITRRPMSVLELAWAVAMGVAPDGVSTIAALAQLVDYQRLLGLIQPFIARVDFNDMNKRQVRLVHNSARDFVLSGWAMASLDGQELPTTATTRELRVDQRTASLEAALLNICVRYLLLADVDQLELFSDEQLAIEELLHDFDPFSENKEQVQYDPHCSWEVWEEDMKHYDPAERGFGELFVYASCHWIDHLGVIRTELPPGSIELLCKKGSTRLQNWINQNCRPGCTIKSRFTFDSSLYDPLGITSLYGSHITFQYMLENADFDSGYYFSDTAMKAADQIFKWGDLSRIIMLFTQSKAGHQLWHVGFFQLVMQYWSVSKRQLQGQDWDAIFDLVDCVLDDMVHDGWGNELLCLASGSGCMPIVQRLIGAAQHKADLREELLRDCQRQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPJ2</accession>
    <name>A0ABR3YPJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">General transcription repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TUP1_1</name>
        <name evidence="4" type="ORF">Sste5346_008642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="358" mass="39576" checksum="6FA08BEDF6F583C8" modified="2025-10-08" version="1">MQMTPAGNNSLGDLDPERLPPHFKKTRDDWFVIFNQQVPRVLDVDLVHTLQHESVVCCVRFSADGKYVATGCNRSAQIYDVQTGEKLCVLQDEAVDTGGDLYIRSVCFSPDGKYLATGAEDKLIRVWDIQTRTIRNTFAGHEQDIYSLDFARDGRTIASGSGDRTVRLWDIENGQSVLTLTIEDGVTTVAISPDTKYVAAGSLDKSVRVWDIQHGYLVERLEGPDGHKDSVYSVAFSPNGKDLVSGSLDKTIKMWELASPRGIPNQGPKGGRCVRTFEGHRDFVLSVALTPDAQWVLSGSKDRGVQFWDPRTGNTQLMLQGHKNSVISVAPSPMGGYFATGSGDMRARIWSYGRYHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPR5</accession>
    <name>A0ABR3YPR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008298</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="606"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="693" mass="75184" checksum="FE810836742055C4" modified="2025-10-08" version="1">MAALSVSRACKGCSQLKVRCQPGPSDSSSCERCLQAGRTCVPADKRRRPRDRIAELEAQVAALSRALQKQQLGDRGDRTSPSTTDTASNSTSSPSATQPPPTVRNAYSFSSTRPTGETAIAFLDARVPRAAQQQAVDLYVKRLWPLIPCFSLIGTDLDTMRRDKSVLFFSIVTFTAPFSLVPSAVRSELLRESMCMFAVELISKPNRRLDTVWSLLVACFFFRAQHGSAHVTVHQLTQMATSMAIDLGLGGAQLPAAPGVALSSTASTPGSVPELEAIEHCASPPASSADPSSPTAPYCTMATKADAQCAWLSCFMSASNLAIGIRRPDASAQWTAHNQSCLDDLTRGFAVMPPDAAHETLFLHMVRGERLCQQVVDAVKLCEPSVQWDVTSLENAQTMATLQTEIDNWTAETTTALVHASNFLFHKILLFYRYATVIYLHEPVLHTATNKLSFGAPFRRSKLAEHDVAHPQVTGKHVASLYALKDACLALLDLATSELDDEDTGDENDNTLTAFLSDAPLSFISKLFHAFFILAKLHIAVTAPGNTYGVVLRPAELRFAPYPGRLAGLADRIERRNPGSFHYKILACAGGAGEWFAEYEANRAKGTLQTPDEESSSSSTSQAQFTQPPDLENSFFYGEPTPIMATDTTADDMAAYLTAYGQSASTTLTGNTGFDVDDAQWQMLDRYISSFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPY2</accession>
    <name>A0ABR3YPY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="527"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1061"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1109"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="537"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="726"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1116"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1315" mass="141492" checksum="A33191D4BA7BCDD6" modified="2025-10-08" version="1">MTTLLGHDDLGLDLSFSPLGNDLALSPSTPLDAVPINDDAGPTITVNTKVPAAGSASATAPGATPTTATAAQFPAPKTDKPRPHVCTTCQRSFARLEHLKRHERSHTKEKPFECDQCTRCFARRDLLLRHQQKLHQATTAPARPRNRRESTTGVAPSRARKSSMASTNGSGSVAASLLNGANSVNGGAANNQMRPRANTISHLDASAGAMHFMGASGPANASIARGMPPGVHSRHPSLAGLPMHNMEQIPMQASGFVGGMSSAMGHRGMSHGLPRLDTHGLNNLDLSGGMRTAPLNNTTMFNSDFDFGTSSYGHSASGTTINPSALQYSDSPHSAHLDPTAIYDRMTGYNDMHQTRDSFSWLTGLTHPNGFSSAIDENAVDGSSPSAISTGSQSGISDVMLDGSNHLNLNGAHAVTMAPPVSSASHTLPATTLSMWSTNGNMVHQQLNQNNFSMDFGATTSFSDLLSGLPLSPNGLHNIHTPMTATSTAPPNTDTYFSATPPSSLTAASPSMMSALNNATFTQALSLNGGTAPETPNSMNGSNSVSSNGQNHRHHQASLNTSSPVSTITDATRLAIVNALNSAGSQTSPFGMRKYSFTGSATAPGLAATPDQSVPSTLDLQKYVGAYLRYFQPHFPFLHVPTISFDIPSNASSSSSQYHRGGYGSNTVGGSGCLILSMAAIGALYELEHDQSRLLFTMAKRMIQLYLDERRKANVRKADFRRTPNGDAQMQQNDGSSDTPVWLVQAMLLNVIYGHNGSDKRAGEIAATHCAALVSLAQGAELLQPTRIEPLADDFDLTMGDGIEPSNIWNTDDGSSTATAKAIKEEAQWLRWKAMEERKRTLYAIFVFSSLLVSSYNHTPALTNSEIMLDLPCDEEFFSATTCAEFMAKGGIAAANHNRMTFHEALGDLLRASEKQMRRCSVNPDGTSESQEELKPSTFGCFILINALHNYIWETRQRHHNKVWTNEETEKMHRHIEPALEAWHRAWTNNNDRNSSNNVDLTYLSSASGMDPISVDSVPLLDLAYVRLFVNLARSKEKFWQRNWDGLAEELCHGREIVQHAEQSPASNSESVMTDPSSDLSGHGSSVFIDSPATQLSASPGFATGKLNGSVGQLGGQQQQQQQQSESTRTTTRREKHLRKAALYAVEALSMTNKVGYTLADFANRELPLQSALCVFDCAQVLAEWVATLQDRVGRYLGVLDQDVDLNQVPAIMLLEDEDGKLLAKIKEVLNAAEMTMNMDIANGTGNAVAGISTRMASRMQMGEQIGYGAKILSVTAYTLGKASVWPVTHLMAECLENHASHMRARAEKSVLACD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRB9</accession>
    <name>A0ABR3YRB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Poly(A)-nuclease deadenylation complex subunit 3</fullName>
            <shortName evidence="7">PAN deadenylation complex subunit 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">PAN3</name>
        <name evidence="10" type="ORF">Sste5346_008007</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal zinc finger binds to poly(A) RNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. PAN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03181">
        <property type="entry name" value="PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pan3 C-terminal knob" evidence="9">
        <location>
            <begin position="645"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="101"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Knob domain" evidence="7">
        <location>
            <begin position="693"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="654"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="488"/>
            <end position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="547"/>
            <end position="548"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="794" mass="86424" checksum="A9E45A0D19D1C0EE" modified="2025-10-08" version="1">MAAPKDIASSKKGLNGDSPVFTPGSANSPLRKSSVLPLQAANAAPFTPLGTSVVSASNASSSASPREQLRDLVGNKDAGMSIPRADSAAFNLASVREFVPRTSDQASGFNAGSAREFQPKGGDRSPFNVAKAVEFRPQSQSSVPPSATPTSTSSVPSQTLPSPQPPQPSLISQQSQQASLAAQQPQQQQHQQAPGQGSLYNLSNGPSQQSQMSIPTGPSRVPTHNNPDHLNNRAGMGGMANMGGMGNMGAMNNLGSMNNMSGMGGIAGLGGMNSMAYGMPPGSEVQLGQGGGVYDSYNVASQGASGGAITTSPYNPYAATSQQPGREGAAYYQGQAPFGAQHQPPGEHLYFPMGPHRQDLLPRQRTVHEFFLPEKMRQEFHMKSRAGNQAAVTLSVNVESYHSLTALDTNSHKVAGSFGRITWLYKAVASKNGKHYCLRRVENFRVSNENALRTARDWRRVNSGNVVTVHEAFTTRAFGDSSVVFAMDYFPLSVTLMQYHFPTYGQTRPRTNVTVQENILWGYFVQIANALRAIHSAGLAARSIDLTKIIRTGKNRIRLSGCAVQDVINYDPARRVLDLQHEDFIHFGEVMVSLATHTPPNELKKPLSSLDQIPEIYSHEFKAAVKWLLTPAPASTTAPAGGKTIDALLTYIAPQVSRFFDMSLQENDSLYSLTSREVENGRIARLMMKLGTINERENYQRDASWAEHGPRYPLKLFRDYVFHQVDESGRPVVDPWHMISCLNKLDAGSNEVVRLSSRDGRTNLFVTYKELNKMVQRSFSDLIRPAGPPRRHHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS32</accession>
    <name>A0ABR3YS32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAM1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Outer kinetochore protein DAM1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DAM1</name>
        <name evidence="16" type="ORF">Sste5346_007792</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013962">
        <property type="entry name" value="DASH_Dam1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08653">
        <property type="entry name" value="DASH_Dam1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="174" mass="19183" checksum="8AD5921E10671909" modified="2025-10-08" version="1">MSSEPLGSSARQRSTSRTRTSRPTTPLRPSSRSSFRESARDSVLGDAHFPLNAFEPAFAELSDAMADLEANMMHFQLMHESLARFSESFASFMYGLNMNAYCVDFPEGPVSESFRRAKQRGEAATADHEMAGLAGDSEAGAGHCRFRPWVDSDTARWAGSARNARSSKHAWRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS42</accession>
    <name>A0ABR3YS42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HpcH/HpaI aldolase/citrate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="25397" checksum="765450568EE7BD9B" modified="2025-10-08" version="1">MVRTILRSASTSYAGPFKWVLIDGEHGLIGDRDYYELVNAIAAEGASPIIRVPWAEEWMIKRALDLGAHGVLTPMCHTAEDAARIVRYSKYPCRGTRGYGPIFAVHSIPGMATGDPAYDEGADKSLVVAVQIESRLGVDNAEAIAQVEGVDVLLVGPFDLAKQMGIVPGSAGHEAAIRSVLQAAHRAGKKAAIFCLSGIRARLRVQQGFDMVSVSTDSTVVGEAMVQHLSVANGTSTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSC0</accession>
    <name>A0ABR3YSC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008083</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="67"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="497" mass="54950" checksum="2B983CD72548AD0E" modified="2025-10-08" version="1">MTNTHIPDTGENARRQSTQNEDKPPLDVEHNDYGVTGATGPDTSAAENADIDPVKLAKTIRKIDLIVLPTMTIILAFCFIDRANMGLAMVVGMGKELEFKSNSYSVALLVFFPGYALCVLPSNYALSKTPVRYWLTILSIGFGLFTLASGLVRNFGSLVAMRILLGVCEAGIYPTVIHVVSSWYPRYYFGKRMTMVGSGASLISALSGLLAWAFSRINTPDYAGWRWIFILEGAITIGAAFLAFFVIDEYPNKSKFLTQEQREIAVQLIGRDREEHDEEKLTMRLVRENIFDWKLWVFGLIYMLCVATTYGLAYFVPLILNDRMGYSGAISQLLTTPPYFFGFILAVTVATVSDRIKMRSPFVIFLQLNIVLGIILTRWGPNTGSQYLGLFFCLGAAIVNSPMIVVYAQNNAPTRVKRSISTAVQLSMGAIGGIIGSTVFRSQDAPTYTPGVIVVLCSSAVIIGICGMLNLYFRRMNRLQKMTGIVLEGQNGFLYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT16</accession>
    <name>A0ABR3YT16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="474" mass="53214" checksum="EF7E0B556BBB6CBF" modified="2025-10-08" version="1">MPAMDADGVEWGSGGEAISDATATVDTVNPFGNVNPGEPADPFAAADPVDGDIFEKEGDEEDDMVVPPLDTLENLPAYSKPAGSDEPDATLEVNSGDEDKSADILDGTRTAVEQLMENMDRDHAMLENEVESLSQKEQEVNGANADSTATAGESPELTEEQADAEALANAEVNEAKAYWHKLNHMYKNIKDAAKDMQGYLAQASARGTGAASRHAVQMLATAAALDEDEDIRKINLMHTTKRSVDVEAETESDADTTNDKVEAANKQGKRPALRCQSEAEKAQLEKEKESKKKLDDDQQRAMYDAQKMYFDPYYMKKWYRENNPKYYVEHFADDIDDDKYKVKCTLVDEDNDGNDGDNNNINNNDVDDDSKVTVELAKRTNDAAPAKGLSVEEKKFRGWLKKEKPEFYRIHYGNDFDSANAKVAKKLEKREVLRRENKNTWEEAYEDKKKNELELKHEEYAIQNMYLEPKIYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTV5</accession>
    <name>A0ABR3YTV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008074</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="35"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="469"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="569" mass="61404" checksum="D90E0F80CA0D018F" modified="2025-10-08" version="1">MPPPPPRIYESTFASAAIPHHESFWQCMQRRNVDDTTPDTVILQEHERPEKYFTYGSAPRLAGLGADGLKSVLGLKRGDTILIVGTNTLDYLHIEFSALWGGIVAALGNASATTNDLLHLIETAQPAAIFVDMGPLMASMTSAIAQSSQPKTRLVGIGERGTATLSFPADFVKDEAAEPLEGPLDLSSVDNHSVPALICFSSGTTSGRPKAAVLSHFNVLAYPILYRASEPTTANRSQRDVFYAPLAHIYGVFVATTMPVFTGGYVRLLRSYTLPAYLQACSEHKATTLRVVPPTLVAMVKLLQSGEGQSLDLSGVQNIVCAGAMLGPEMIRAVHQLLGQDVAIVQAYGMTEGLATIVSRFAASRKQGSVGRPVSGGRMRVLDDNLIDVAPGETGEIFISSPTVFMEYKNDVATTADAFPLNDLGTNAHAVSFLRTGDVGHVDADGFLWLTDRKKDMIKYKGHQVSPAELENLLHSHPLVQEAGVCASWDAVQQTEVPVGYVNFVPSVGHDERSAVREKVRAFVDGQVVPQKKLRGGLFYLAEMPRTATGKLLRRNLPARLEAARTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTW5</accession>
    <name>A0ABR3YTW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_007603</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8 9">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="147"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="279"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="407" mass="43968" checksum="A20F7B78FE718DFA" modified="2025-10-08" version="1">MSGGGFTSPFGANSNPFGPPASDSSSRRAPDSAGMQQVLEEEENDVVTSPTSPFALKPSTVTGGPSRALFPPDSSSNFSQTFQNFGNSAPPNPGEYPAQYNFGRRTSVSAESLKPVTDSYDNWSPPVHQKSPEQLERLKAAIQGNFLFSHLDEEQSAQILGALMEKPIPTKGIKVITQGDSGDFFYVIEKGSFDVYVNSSGTLQAGPEGLGTKVDTIQAGGSFGELALMYNAPRAATVMSAEAACTLWALDRLTFRRILMESTFARRRMYESFLEEVPLLATLTPYERSKIADALETQKFAPGATIIREGDPGHSFYLVESGEAEVYKSGTDSPVKHYQKGDFFGELALLNDAPRAATIVAKTDIKVATLGKSAFQRLLGPVEGIMRRTRYEGVKTGVEDLDPLQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY5</accession>
    <name>A0ABR3YTY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1152" mass="123983" checksum="9CDD24AB28D587C6" modified="2025-10-08" version="1">MSDLTDLAELASAADAMDVTGSGDSADSTADAEGTTDAEGTTDTSASDNTTTPNDAPTVATLAAISPSSEAVHTPGSPHTSVRTSEDTSVTTRSATSTSTTTSSRSRRGRASGRPLKINYPKKRVSVACDVCRARKTRCDAKRPACSFCAQLGIDCVYRRGSAAAGGSNNNSSASVPTTPKDSVSKTDIVARLGRLESLLREKESVPYVATPSDHGASASLGVAPNIVVNSADDERADGPLPLFGYRLDSLSRLGPDAASLPSLQALCHLDVDAELETELFGQSTAATGLLMSSGLEERLLDLSPRRCWSLEQAFSRDVLPWCPIIEQHECAAIVARAAEDGFPRGRLETAVALLVLALGSFARESGDPSLKQKNGGGALPGIDYFHAGRQVMHNAAGASGASARYSIMRVQCDLLVTFYFLFSLKPILAFEVLSSAGLRLLMLLQLRSSSTSSASAAARAAGSPASSTSATTATGSHVDGHDDPTYDERLHRAYWTCYLLEHELQAYVSFSARLLQERRDFVPLPLSNYDEPGMYWFLSEIALRGICSSMQDDPGYYSKKRGGGGGLGASIGRSSSGIGTGGVAWNEHMLDAPMLVEEVTLQLLAWHANLAAPVSFPLDDPSYTSSLGVVGVPMLRPLLDPHKVFLRAQFYAVQATLRWPFVVQLLTDQQAPTATSSASTSGIDGAAASLHYAVLHVYAVEPLMQDRHLMLFANISGLFCVTMLLLCAHGLPQLAAIQHPGTEAAVRAALASLRIWQGEPNVQAMVARVEALAQSKVVSAAPSLLAVFAADTSELVGLLARLALSDKSPSSAAVLSAALSLAAFHKHGLQTEADVYIYNLKDRALQTLLGSCSPDNVSNRSMVAQHMAASMLLSHLEMLGLPNIVPSWFCHLRHAKTLIDNVVTNADAISFDHSFSGLIGWVEYHMVMARFSVRHWYRYEGEPRKGVKTEAVTASEQGGCLPPKIKDVAPGTHEIVRLLGLLLDTLRPSSDEHYHDEAYERSLRCLENRITQVEDGSYEGTSWPARVELLKLAALIYLKRAPRNFSGVSPEIDALVERAHSLFGSLEKDAPPTFALLIVGCEARNDEQRKNMLVYMERARKTSSLRSIQQVQYVLQKIWIQDDLAVDDYEMDYIGRLDTGITSFKMMPGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU49</accession>
    <name>A0ABR3YU49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007679</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF867">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="209"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="40665" checksum="49B16DCABA822426" modified="2025-10-08" version="1">MTTTTTTTATDTAKKLNSVELVNGKVVEFISNDAIEADYVPVIDVSRMYSPDLAERQALAEEIGHAARNVGFLTIVNHGVDMALAEAVFKQAKEFFNQEREKKMQVYTGLIPNEYIGYHPMHEYNANEKKYQDLYEAYNWNFEEDIGPGEDDTAHPPVANLWPTNLPEFQKTLGTYQAALVGLARRMTRMFALALKLPETAFDDYIKTPEASMRILHYPVQTASRDDQNGIGAHTDVEHFTMITQDCDGLEVLRKDGQWVKVRPVADSFVVNIADCFMRQTNDTFVSTVHRVINTSGKERYSCPFFFGFNRATVMTPIPSCVSEANPHKYPVTTAGEYYQWRTKRQKERGLGARTTKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUG7</accession>
    <name>A0ABR3YUG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="10"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="447" mass="49377" checksum="C3A0F1BC07093845" modified="2025-10-08" version="1">MDESTPTLRIAISGAGIAGLAAAISLRRLPGVVVNLYEQAAAFREIGASIGIGPNGLRTLEKLGVHNALREGVCVRQKGRHHQVYRHWQTGEILDYDTHRAVTDPLHATARFHRAHLHAALLEHVPVDTIHLGKRTTRVATTDDGVVLFFSDGTSASADLLVGADGLHSSVRKWFVPQHKLHWTGWVAMRSTFDESLLDGVDFPHDAAHWVAPHRSFFHGRLGHGQFTTVGGFTVDPSNPPDTYKNVHWNDEGSLQRLRDLYKGWHPTVQSLLEKTPYTRLYPNMAGDPLDTWVYGNGRVALIGDAAHTHGGAFAAGGSLAIDDAYALLLALQHVWPQQPDTRPTPAQVYHALRLFEATRRPHVAKVMALARHQIIGKLAPGEKAKEPEVEETAESSVDDHEKLLAFIKSRPDTAWINEHDVEASFRAVVEAEASRVERDRLPQSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUN9</accession>
    <name>A0ABR3YUN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-(Apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="10">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">APN1</name>
        <name evidence="10" type="ORF">Sste5346_007512</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002199">
        <property type="entry name" value="PRK01060.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445:SF0">
        <property type="entry name" value="APURINIC-APYRIMIDINIC ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="9">
        <location>
            <begin position="212"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="120"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="499"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="56620" checksum="543D6B0A39458597" modified="2025-10-08" version="1">MSLPLRQSPRKKTSSNSAAAAWKNLLSGGDASKKQSIRTTTVVSADTPATIMAPRGRGRPPKAAAAVVEVTETKIETAKTTAKTTTTRIKEEEVSPIKASKVSRTASAVKATALKLAAKSSTASLKRKAKEDPEEEGDHLEAKAEIKAEEEVKDVKSATPAKKSKAAKKTKTDDDAPLAERADVKTLKKTMYIGAHVSSAGGVQNSVPNSVHIGGNAFALFLKSQRKWQNPALADDTRDAFHAACAEHGYDAAKHCLPHGSYLVNLAQPDKDKADQAYTNFVDDLRRCDALGIRLYNFHPGAAVAGSGTREAALGRIAAALNRAHADTAPSKVVTVIENMAGGGTTVGDKFEDLAAIIDQIEDKSRVGVCIDTCHAFAAGYDLRTPESFDKVVAEFDRIVGLKYLRAFHVNDSKAPLNSRRDLHANIGTGFLGLRAFHSLVNTDAFAGLPMVLETPINRVGANGKDFEDRQVWADEIKLLESLIGMDADTDDFKAKEKALQAEGAKERKRVQEQVDKKSAKDAKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVS6</accession>
    <name>A0ABR3YVS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="117" mass="12668" checksum="A9EA877F61876B19" modified="2025-10-08" version="1">MASISQLDGTCSANCCNADGASDEPCATYDEPAVKPSFESSIERIDYASTEAPAELRTREPSDEPVLIPTKSRGYSEEPASKKIKVTPKKDNAKQITPEKTNYFGTSEGPMTNSEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWW1</accession>
    <name>A0ABR3YWW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KEL3</name>
        <name evidence="3" type="ORF">Sste5346_007044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="613"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="716" mass="79484" checksum="7311D10BA11736EC" modified="2025-10-08" version="1">MAKDKKAKSDGKKAKAAEKKQKQASKAEKKAKVKNAKQDGSDAEDVDLDQVLEEYRRQQELFLKVTETVAEGPPRARAAACFLASPANANQLLLFGGEYFNGALATFFNDLHIYYIDRDEWRTVTSPNTPLPRSGHSWCRGGNMSNSVFLFGGEFSSPKQGTFYHYNDFWRLDPAAREWTKLDTKGKSPPARSGHRMTYFKNYIVLFGGFQDTANQTRYLADLWLYDTANFVWFNPALPPAQLKPDARSSFTLLPHEQGAALYGGFSRVKANANPGGGGKGGGGGGKTAMKAVVHQDCFYLRITPPPATAAPGTAPVVRWERRKKPANAPNPTRAGATMAYHRGRGIMFGGVHDVEESEEGLDSEFFNQLFAWNIERNRFFPLALRKPRAAAKKAAGGGNEQRVGRRNRAAANEEELLKQLAALEATSKKKDGDDDDDSSDEDAMDVDKKAAEEEEKSPARQMPVSMEMPHARFNSLLAVQGDVLYMYGGTYEKDDREFTFDDMHAVDLGKMDGCKEVFSRPMDDAWYESEDEEDDEDMDEYEDEEEEDEDVEMEDEGVPKKFTPSSRKKNKGGDATEASDTASTADSETPASSAASTADSEDTEATEADTPVDDGLPHPRPFESRRDFFNRTSNEWQEILMTQLRWKNIKVESMLVKEIKTKAFELSEEKWWDCREEITALEDEQEAAGIGEVVSLADREGGGGGSGGGGAARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX34</accession>
    <name>A0ABR3YX34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein SOSEKI 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SOK1_2</name>
        <name evidence="2" type="ORF">Sste5346_006892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="182" mass="21176" checksum="12FF9F634C1B6C7D" modified="2025-10-08" version="1">MLSELDINKIVLNPTLRHDINYDRLLSFIPKLNCESGRSKQEKVQQFWSGLHHDLTQFVANRKGFLRAHGPNDNDWSLPILLNEVKDIIQTLVPAQDHDMLEEVLDILWLMQQFARGMLDIEKLAGWLSSVLKTHCAPMRDKWVNNMCKELKRGHREKDIDELVAGMTSLLRVLTRRRSNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX83</accession>
    <name>A0ABR3YX83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Vacuolar fusion protein MON1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MON1</name>
        <name evidence="9" type="ORF">Sste5346_007039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">In complex with CCZ1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis. The MON1-CCZ1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endosome</location>
            <location evidence="4">Multivesicular body membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 4">Prevacuolar compartment membrane</location>
            <topology evidence="1 4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Vacuole membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MON1/SAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="6">
        <location>
            <begin position="248"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="7">
        <location>
            <begin position="410"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="8">
        <location>
            <begin position="563"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="671" mass="72444" checksum="934F702FA4273695" modified="2025-10-08" version="1">MAEPNDGEAAPAAAPPVTDTAGDTSSNTAPEDAPSQSSSPPPPLPPRRPSSPGGSPRRLESAQLQAKPKATTAVSSIDIQTLSFPDGSRGTFSTQGMRAVSTAASSSTSPSLSLRSKQQHRRAASSSGGIGSISGIGDLSDVPTDAMSVMSFAPTMRPPGDLASLAVGDFHRKSRAWTLLRTQATSVQPFESTRIARVPYSLADFDKEFEEVQDDDESDASGGEAGSGKEQEALSEEVRLAAWKAKLKHYMILSSAGKPIWSRHGDLSLINSYMGVIQTIISFYEGADNPLQGFTAGNARFVIVTEGPLYLMAISRLGESDSQLREQLRALYMQILSTLTLPTLTRIFANRPSTDLRKPLQGTEGLLASLADSFTKGSPSAMLGALECLRLRKSQRASITSTFLKQRTDKLLYGLIVAGGKLVSVIRPRKHSLHPSDLQLIFNMLFESGGIKSGGGENWIPLCLPAFNNRGYLYMYVSFFDAEGGEADPKKASTSPSTSDSESIAIVLISADKESFFDLKEMREKVAQNMTKNGGLALIRAAVAAGRPHVADIVKRPGTAVQISHFLYKSRANVQFAMSAEESQTREDRRRLMTVYHQLHAAVHARHAHLKILHCVGEDATSLVWVTPVFEFYCVAGPNASRAVVTQDANRIIQWAKREEERLFIIGGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX91</accession>
    <name>A0ABR3YX91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="216"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="663" mass="71316" checksum="4E11F6959D5B64A6" modified="2025-10-08" version="1">MAAKSAPLPHERRKGESALSDFADYVERQQAVRYPLNAGAAGGASTATTTTSTAASTAPTSVASASTVSRDDTLDELDDILDALDLDDAVPRVPMRQLLTAPESESGAEALSTLLTERIDDGNGEAVLDLGFEHNGDTLGLTREQWAVALARVERAADHAGADCELLLTRNVGGPLDVVQDGNGNGASSGNGTSGSSTDCTGKLMVRRRPRKVEEVIETRIAVVGNVDAGKSSLLGVLVKGDLDDGRGKARVNLFRHKHEFETGRTSSVGMEILGFDTRGRVVASDTPGRKLSWEEIGKRSAKVITFTDLAGHERYLRTTMFGMMSTAPNYCLLMVAANNGLIGMSKEHLGIALALNVPIMVIITKIDICPPNILAETITQITRVLKSPGARKIPIFIKNRDDCVNTATQFVSQRICPVFQISNVTGQNLDLVRTFLNILPHHGRYDAGGAFEFHVNDTYSVPFVGTVVSGIVKSGVAHAGDAIWIGPDANGHFAPTTIRSIERKRLAVPAASAGQSASFALKKMRRKDVRKGQVALHRTDDTTPPRVYREFVAEVLILSHATTIKRKYQATLHVGPVHQTCAILDMDRPLLRTGERALVAFRFLQRPEFLVPGDRLLFREGRTKGLGIIKSVGYDPAHPLMPKQAAGDEAEAEAEAATVKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYJ2</accession>
    <name>A0ABR3YYJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF28">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="23430" checksum="526CF04D3EBCB2F5" modified="2025-10-08" version="1">MASDPIVEELKNFTACDVADALLKLKVPNGGFLAGITLWSPERQAGATKIVGPAYTVKYALNTDPAPKVQGHYIDGIPSGAVVFISSPPTPNACFGGLMSTRAQASGAAGTVIDGRLRDLQEHRDLGYPVFARDVSTTAPQEVAKVVGIDVPVTFSGEYNQNVTISPGDYIVADLNGVVVLPKDLAAQAIPLMAPQVEADEKMAEAIKGGMTFVEASKKFRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ8</accession>
    <name>A0ABR3YYQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">54S ribosomal protein L12, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MNP1</name>
        <name evidence="6" type="ORF">Sste5346_006594</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="117"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="184" mass="19553" checksum="2164F67BF78AD5E4" modified="2025-10-08" version="1">MPMTCRYAAQRCASQLRMASRARPTMASFCVAPQQRIARRHNSTEAAVDPKITTIVDQISQLTLLETASLVSSLKTRLNIPDLPVGGFAAGPAAPAAAAEAAEEDDAPAAAAEKSLFTLKLESFETGSKPKVIKEIKGLLGLSLVDSKKFVESAPKVMKESVPKEEAEKIIATLKELGAVVSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ18</accession>
    <name>A0ABR3YZ18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short chain type dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF4">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="23085" checksum="4F0327CB9C43C50B" modified="2025-10-08" version="1">MPAPVALILGAGANVGQAVARAFAAKGYKIALVARSLPKETSSPADYLHIRGDLADPSSVAGIFAQVKKELGLPNVVVYNAAAGRPAADPFAMPLNDFVSTLHINTTSVYAAAKEAVAAFSETSTPGVFIFTGNITNTKPIPVMAPMSAGKSATAALIQSAVESAKFPGARFYYADERKADGSPAYGAIDGEAHAELYTSLARSSTQGPWLQTFVKGVGYKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY5</accession>
    <name>A0ABR3YZY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAD superfamily hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF57">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="55379" checksum="79D1BECB81FC1641" modified="2025-10-08" version="1">MGSRSCLVDRLLTAAPRVPLRHFVAESRRRGIATTRAGSCAYSHLRTTAAATTKTTPRLSCAAPRREQRRAHSTPATSSSSSPDKIPPFAFAFDIDGVLLHVNEPISGAAAALRYLHQQNIPFILLTNGGGRYEADRVADLQRRLGLDTDPDCGGPLPVLSPANFVQSHTPFQELLDDAAGLDAATEGGKGGGLRDQTILVTGSDAARIRTIAEQYGFSSVITPADILSAYPAIYPFEPLLKSVYAETARPLPKPLLFEGGKLASQPNAKPFSPADFDDSKYLRIAAAFVFNDPRDWALDIQLLTDVLQARHGFLGTFDPASLSEKGLPAEEQGTRLFFSNADLLWATTYHLPRFGQGAFAAAVAGVWQQLASPKQAPLLSPENGRATLLGKPHAATYRFAERTLLRYRTSLLEAHGGGNKAGSKASSKASSEADGPLKTVYMVGDNPESDIAGANQFSSAHGTDWCSVLVETGVYDPARAGSSPDYLRHRPRAIMGDVGAAVRWALQREGWPADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z000</accession>
    <name>A0ABR3Z000_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="234" mass="26607" checksum="F5B5B582AD428BB4" modified="2025-10-08" version="1">MAPPKNHELKREKDCFAVTPERKYYRSGDTFIKRNLRPGEWQQHNGYMHVPIFNFERILNEGACLQFVAEHTNVPVPKLLACFEDDGAAYLVTEYVEGVGMDELSAEDQRTVAAELEQHLATLQALTSDTWGGPDGLVLPPYRVMRHCDRRPYRLRPRETADLVFCHNDLQAANVIVNPSTLKINAIIDWEYAGFYPPEFEKPFYQRPGPSVALDGEENDEAALQALLDAAKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z051</accession>
    <name>A0ABR3Z051_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="5 10">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PMI1</name>
        <name evidence="16" type="ORF">Sste5346_006151</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="5 10"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046456">
        <property type="entry name" value="PMI_typeI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046458">
        <property type="entry name" value="PMI_typeI_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20512">
        <property type="entry name" value="PMI_typeI_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="14">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I helical insertion" evidence="15">
        <location>
            <begin position="167"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I C-terminal" evidence="13">
        <location>
            <begin position="358"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1894009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="462" mass="49737" checksum="93429EA07F71D5AC" modified="2025-10-08" version="1">MQIPLIRLQCGVNSYDWGKKGTESVAAQYASATPAPGFSVQEDKPYAELWMGTHPSNPSKDVETGRNLLDLVQDNQALLGSTISQKYQQKLPFLFKVLSVNKALSIQAHPNKKLAEQLHARDPKNYPDDNHKPEMAIAITPFEGLCGFRPLAEIAHFLKTVPALRELVGEDVASAFEKTVTGYETDDSPEATQKNKDALKSLFSALMSAPQTALASATTKLLEAVDSPAADEEFAAGGVESSSGATLAKLIQRLYGQFGVDYGLFNLFFLNYVTLQPGEALFLCADDIHAYISGDIIECMAASDNVVRAGFTPKFKDVDTLTSMLTYNYAPIDEQKMSPVDYPYATLNRPAYSSGSESILYDPPIEEFSVVRTALKSNGSKATLDPLEGPSIVICTGGRGTISVGPKVEQVEEGYVYFVGATAEAVLEAKSLNDGEEFITFLAFCEIDSDGNAAAANGANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z093</accession>
    <name>A0ABR3Z093_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="50924" checksum="319301B3018C86C5" modified="2025-10-08" version="1">MDVPKFEDLPSIPGGPRGCAWEVWNNIHAQTAVPGKDGKKLEKDGLGTLNHLTATVVSAAGKEIQTGDRAALNWPLDAYVHVGFGRKKLDFKLIDGFEVTNGLLLANDDEISFNTQISSQWDGLCHFAHQKTKVYYNGATHEEMQAGRDRPGSVHAGGICGRGVLIDYYAYAQTHKIQYSPGETIAISVADVEAVAAWEGVTFQPGDILVLRTGWTQWHDALKDDDPAKFIVKTHNAHNNAGLLAGEETAAWLWNRRFAAAAGDNPTLESWPPSGGQMLHEYLLPMLGCPIGELWDLEELSKMCAKNKRYSFFLASAPLNVFGAIASPANVFNPSHTADALADVKYGACRWGRGVVVPGGQDNQVVAPDLSTKIDTQYLLKTDDDEPAYITVYTEGWRTGPADVLARLFDPAQADGVAPSDYRFRLYVHLETGDARYQLLCTGMWVASGARLRSRVLYDVYRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D6</accession>
    <name>A0ABR3Z0D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632:SF2">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="40"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="451" mass="48901" checksum="B75B309ED694B949" modified="2025-10-08" version="1">MACAPSARPFIALAAVPARRGLASVAAAAAPVTSATSNHKVVLVGAGTAGLSIGHQLLRSGKFAQDDIAIVDPATWHHYQPGWTLVGGGLKNKEELQSRLDEMIDPNIKFYNDSVGKFAPEQNVVTLGNGDKISYEQLVVVPGVHIDYSSIRGLPEALADRNSLVSTIYSYDHCDKVFRTIEALQKGTAIFTQPAGVIKCAGAPQKIMWLALDHWKQTGVYDPTNPSASPVKVAFATGLPVMFGVPKYSAKLDALRQERGVEGLFERDLVSIDNGNTATFARPNGQEKVTRKFDFLHAVPKMGPHAFVKSSPLANAAGYVDVDDATTRHKKYANIWSAGDASSLPTSKTAAAITAEAPVLVGNLLNAMEGKAPQEQYDGYTSCPLLTEYGKVMLAEFKYGGVPKETFNDWFGIDQAEPRRAFYHLKKDFFPWVYRNNMVKGTWGGPKGWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G5</accession>
    <name>A0ABR3Z1G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleobase:cation symporter-1, NCS1 family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006183</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF15">
        <property type="entry name" value="NICOTINAMIDE RIBOSIDE TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="59274" checksum="DD2B11E76F23E21E" modified="2025-10-08" version="1">MGVNWAAFKKRIEVPKHNDSHYENTTWCNRDLIPIPPDRRTYGVWSYFGYWTVSGSCISAWSVGSTLLAYGLSPQEAIGVVIIGGVLTGMLAVACGWLGEVHHLGFTVSSRSAWGMRGAYFPVIIRIFVSCMWFGMQAYWGGQATRVMIGAIIPGFAHMKNSFSASSHLATNDFIGLVIWMLAFVPAVLIKPERLQIPFFFCFALFMGTCIGCLAWSVAHAGGAGSLFHEPGTAENKGWAFMFGITAILGSWGAGTLGQSDWTRYAKRRYAPTISQMVASPVTITVTAAIGIIVTSAAHDILGGDLVWNPIYLLGDIQELYHSSPRARAGVFFASLGCVASQLSISVILNSVSTGMDMAGLSPKYINIIRGSYIMAIIGIATQPWQLISTATKFISVLSGFGVFMAPATGILLSDYLVIRKRKLRVNELYMGNSESHYWYIAGFNWRAFVAFFSGVCPLLPGLAATVNTYTNPKWTNWTRLYNLTFIVGLSISFVVYCSLAYLFPMPGLGVDTPFVDEFDYVDGQPSPVDGNSSEKVAPDQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z5</accession>
    <name>A0ABR3Z1Z5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6987 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054256">
        <property type="entry name" value="DUF6987"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461:SF1">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22485">
        <property type="entry name" value="DUF6987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6987" evidence="2">
        <location>
            <begin position="36"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="241" mass="25567" checksum="CBC17346C883E343" modified="2025-10-08" version="1">MADIQSAPSPPKTDSATNDPKNSSGSSGADAKDPDADKKEQDKKLAQQMTTALERCLDKVKPICDMIAQKIEKADRTPKEDLDEEALVKEVKPLIEEGGKILTEANGVVRGLDPDGRIQSQAKHHSATHEATPEEYKLADVLKELTEKVAKTIDDAKKKLENMPKAKEELNPLWALLSDPLAQILAAVGLLLNGVLGLVGKLLGGLGLGGLVDNLLSGLGLNKILDNLGLGSLSSSLTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2B0</accession>
    <name>A0ABR3Z2B0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Telomeric single stranded DNA binding POT1/Cdc13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1151"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1478"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1614"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1692"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1913"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="298"/>
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        </location>
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            <begin position="325"/>
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        </location>
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            <begin position="512"/>
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        </location>
    </feature>
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            <begin position="661"/>
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            <begin position="696"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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            <begin position="718"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="765"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="783"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="806"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="855"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="965"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1080"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1273"/>
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        </location>
    </feature>
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        <location>
            <begin position="1488"/>
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        </location>
    </feature>
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        <location>
            <begin position="1518"/>
            <end position="1538"/>
        </location>
    </feature>
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        <location>
            <begin position="1556"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1702"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1920"/>
            <end position="1930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1985" mass="212853" checksum="582912E0EF861E8C" modified="2025-10-08" version="1">MSAENGGGRDGGAEASVAAILAAATVTPIAQLGPDLTNNFGSIPRAVRGDVTIVWPYNSVSRSLAFLLAEPDVRLRRSKGQIRVQLHGASAAAVAESGLGGGDELLLSLQGASWSKDESSLKLPGSRVEWQLEFRGCIVLQAKVGEIQEARAININQPDNETNGNTEIEPARDGANGTASPDYGPPPSSPPISDLFRSPMPPRVTMTNNEEYASPAFIKRARISFGSLFEPGFDIFEEDGDVRGRGRKRTRFGRPSNSWRYSSRSVSPEQEPRHATPPEDEEESEKKEAPTVEVPTSPAVALQAATPTPAPRPETQTAAAPKSPVPQTESQPQQVDQSMRSSPPLTTSQIKTSTPANRQEPTQQAAAAAIAASTTNVFGSVPDVQMGGMSNPFAASQRSPSTLFGSTTQPSSSNPFATSSLPASTNPFGAPTSTTTTNPFGAPASSTNVGNPFGAPAVTENANPFGAPTAVPFGTPGADALGFVADAGLFNDNVRFSFGDPTNTFEQQPLDPHLDHAHDTEVPALPSTEDHFAESQYQYPEPPSQHTSHTSAFGHGGFGAPTATTEEAHPEMNEPPRSTGQDQMLVWPISAPTLDAEHAEGAIPADTLPMSHPATGTQTPSVETPNNNNNNIAAASASFIASGANEGVFEDDDTAEMASDLPREVDVYGYNDRRYQNEQEEAMVDMVDDGPPSRESEEDDLESDGPEEAEPTDHLAAEDEDEEEEDDAEGDDDDVEPVEVIDEDGGIQVEDEAEDEESEDDVDSEVEKTDQPGDDYDMRNYAEIDDDIEGEEEPDEQGGAATFNGEGEDDEEDEEDEEEEEEEYDEEEDAEAEADDDHYAAAPQHSFSTGRRLDEDEDEEMGSEEYDEEEEDYDEEEEEEEEDDGGHQSMGYQRPRMFQPPARPSQPAEPVVIDLLSDSDDDDAPPPPRQQSKPVSETPIPPPSVPVFGQPSGAQKHPEAASNPPEEEDEDEEEGSEGEEEDEGGFEEEEQEELIEDEAEEDEDDEDEGEGEEEPEEEPEEEENAASDGSDDEMEIEEPQPEPKQDEPAAATEAEPETKSESEDEVEKEMEAELDAELAADAKAEAEAEKAEEVKETDEADEVETAEKTEDIEDLPADTEKVEAIVIKEPAETTEAHPTENFEVVVEWTTEQATVDAPVEVEKVDDDQDAPEAVPEASQQDAAEKQADAEPAAPEPPKSPAAVEVEPVTEKQLEPEPATETQDQQDVDSEDVAMAEADVEVHEEAQPEEPPEEVVIELSEAPPAPEPAHKTRSQTAQLAQEATAQASASETPFSPPPTQLGTSQDGAAEVAVVDLPSLSGTQTTEHAEPSAAQAQAHLLTPMQTQEGVDSNIERHDHFQGASFTYTEVTSIAEEEDIDGQIQSQIMSEMAISFEFDQQQQQQLADIDMHSVASGADVEMADHNEEGDDQMMDEEEAAQTPRQTVQDHGDSMDVDAGTDIDMQSVVEEVLDEVGIVVTEPAPEEEEQASDAAAQSAKPADASTEARADKEDAEAPATTLHKDANEKTAEEPTGETRDQTKSSQDQQQQQHDDQHPQVTTEDTVSTTEGRHKMSLRSTNSRLRRSLSPQLVVSSSTANDASNKAAASAAAMTAAVADAGSPEEPDASVQIARGATTRRSKRARAASASQPTASQDDGAAASAASAGAAAVAAAVNPTKEDTAAGEDVSVLIARGATSKKRTTPKAKDNKEGEKKEKEKEKTVEPTILAPPPSMAEVKLALDRCRDTVPDCVQLRNLRPRLRTLLDVAVVATSSSDDHPPRRTRTRQYAMSLTATDPSLVEHVSASRHHLHNLHGGTGSRRASPAAVVTNVNDNASDTGSVSVSTSVAAGTDIDAIIEVSLFRAHKDTLPTFHAGDGLLLRRFEVVALHDKGFGLRSTDESAYAVFPAKEFVEEGADDKEGDNNGNASPTPQVNGPPVEDMDREARYISLLKQWYHLLDEGACAQLSAANARFVAVDEAAKLVEGESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2G3</accession>
    <name>A0ABR3Z2G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="377"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
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        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
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            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
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        <location>
            <begin position="266"/>
            <end position="346"/>
        </location>
    </feature>
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        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="702"/>
        </location>
    </feature>
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        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
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        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
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        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="702" mass="75821" checksum="529789CBABDE36AA" modified="2025-10-08" version="1">MATFWNADRIGGSAYPLGIDQPLRPRHGSPAANATRSSPFGSGTLQDGEHRRPRLTMDALAAVEDEYSRQDTKLLEDAQKKAKPKAEAALKDDDASSDDGILPGDSYSDDGTNCLDPNNPCRDDISTGASSGGIWEHNAQKLFRNGPEFRSCIMGWIGTVQEVPPLAEKTFNTWQKYDNVVDCVTSTLLRPPRVPEAFLDGSGTGDAGFDERAATQTANEACGLTRKGDKLPAAVSQRNANAPNDSPVPKKEPEVQNETRYVHYPQYPQATPDRGTAKQSTVQPETKNASGTFEPRLVQPTQKSPIPPPRSPLTAPQPKVEPKVEIKQEPKQEPKQEPTPAPRQPTAALAVAPAATATAGPLAGVQIVKAEDKHVEGMLAVYNGDVAKSLYAIVREPVSLEGFRRLFTASQKFRLPSFVAILEDREGEHRIVGYVVVRPRHDVGFDGPLYAFCADCSIIVRKEFRNRGIGQQLLGKALLAIRANFVDKSCPMPQYFYIEVPCGSDDGLAEKKYIATLTTKFGLHYYGRPVETLKWTSKGPMSLKHLLFFHRCIPTVADVPVMASVSDGAVKNIGLPGNVNSQAQQAKVQPMTPPVQARPTPPLTQPTAATTAPVHAPVQAPAPATAPPVGSLMSLPVSGTKNNLAHGRESISRSRFHEKLLQDLMSAPATAPASYAGFKNNDRAPAANATNSKAAPDSTEFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2L6</accession>
    <name>A0ABR3Z2L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Benzodiazapine receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20593" checksum="CCEA25754516F97C" modified="2025-10-08" version="1">MTSFLYHIALPEAVFSSPAASILLPIALGTAVGYSTRPQVNDPEVQALKQPPLRPPARVFGPVWTLLYGTMGYAAYLAVGQTTAGLDISWNTKVVSAGLYTLQLGLNLAWMPLFFGLRRPIEATVDSVALLGINGYLMSLWLDNPATEAAGWLMMPYVGWLGFATYLSAGAGYLNDWTFGPSKSTKGTKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z306</accession>
    <name>A0ABR3Z306_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low temperature requirement a protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="BLL5714 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840:SF1">
        <property type="entry name" value="BLL5714 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="569"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="614"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="814" mass="87733" checksum="3C83A613CD37337B" modified="2025-10-08" version="1">MGDGGGPSGDSSTPSPKSGANATSVSAAAEATAAANAASGSVPASRTPSNNGGGGGGAGKSRRRGSKTGRRRKPQEFLMPDGRRVLVALPEDVDALRSKYAGVTREAADGGDGIPQVEVVVHGSPEHKQFLQESQAHHQSRRDALRAKYGQEILEEWDSVTADFDHVSKELEKLADHSASLGHNFSKFGYSATLRTFGGDEGHGGGHGGGGSGGHGSGAASASSSRGGSQAGSSANSIASGTDDDDDDDSGSGDDGGKSGVPVWHNQNNGQIMQLFKRPVVKQYFHRGLLWRASEETSVQSFELFFDLLYVGIIAVNGDHAAESADGFELLRFLVTFCLSWKIWSDVTQLVSWFSTNDVVQRVEILFLFACLLGVTVNMVQTFYGWGSSGEGSSESVEPAASGSGEAARRSMLFWREESATETSESFLADTYPALAAYYVTARLFMALYCFVTGLLVPLVQGTMFCQVALTVIGAALWIASIHLSMPVRLACVFIALAFDLFGGSIVVGLFRYANSHSNTSFGRYLITKVFDFYPAMNIEHKVERTNAFISLVLGYSVVGVLYQNSHGYGVNAFLGKAVLGLVQAFIFNWIYFDIDCTNIHVHAIRRRAETAYIWQYAHLLFTLAFILSSAALTRFVVATDSPNSPYDSLTEMYQERSSPELSLGLRLYYSTGLGISLFSMTLIALCHQHKIPPTARLPKWARMANRLVVATIFCALPAAQKLTSLQVMSIATGLIGWVLIVEIYGQSCVGDRLFETHETGGYTAKCSQRRLRKALRDAQREVDGDVEGGGRDQPQIDVNVLSQGQKHGAIYME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3A4</accession>
    <name>A0ABR3Z3A4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pho80p cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PHO80</name>
        <name evidence="2" type="ORF">Sste5346_005775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="58819" checksum="E495F70952AA98F7" modified="2025-10-08" version="1">MLTRSANASPIIHGFHYAPSHPSPRHSTSRNSAAAASTPSSAAASAARRPSSSSSPLLVSTASNASFSDRASASAPSSPALSHADSQPLTPLSAPLARRHHHDHYAPPLSRSPPRYVAVDAATQYSPMEPFDYTTAPRNHQQQQPPSSIPHSSAPATAAPPHSHAPDPSSSSSQPTSKQSTPREIPPIPGPIPMEPGIEQGVDHAAASAAAATNGAHLTQGGRPAPGAPVTAPSATVSATASAPVSGTASGSPSVSASAPSSLSSDNAASVSSATTSAQPQQRYTTSPQKRRSSPGPPASTGRLPSPSVADNPPTVAKRARPEAAPVKLLPEQYELCPVEDMVVLIANMLGELIETNDALALKSGHLTRFHSRTPPGISVLDYLHRLAKHATLIPPLLLSMVYYIDRLCAMYPDFTINTLTVHRFLITAATVAAKGLSDSFWNNSTYARVGGVRVAELKMLELEFLYRLEWKIVPNPEVLAAYYRPLVERCPGYALPPDHSPSRDEDDMIDDDDDDETTNNNDGLPAGSAAPAGNGHNRQSSTSLIGEDLVVSGLTRQTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4F7</accession>
    <name>A0ABR3Z4F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12261">
        <property type="entry name" value="RRM1_3_MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="44575" checksum="B887FFCAC955C440" modified="2025-10-08" version="1">MCFFYMLFIANIAALQDRLCTLLNPEQPSVSESAPNATNELVFQISQHEFNSLALIARQYANLRRNLLLGGVDEATLDTLSADEPGSDELSLQPQPVNTTHSEKLNNKAQAKSNSYTGENNTASTSSSTSQKSQYHTSAPPLSSSSFVDECDLDDAEDVGEDGGGAAAAYDRKCLRTLQLVSLPESATLADVAAAVRGGLLLELFIRPHDRSAFVSFAREPDAKAYFEHVKRHDLYIKNKRINVVWSQRQHTMLPHIGQRVNTGATRNLVIRQCHPKLTEASIREDLSHIHNLVVVSVAFGPGDEGHGKNCYINLNSVHNALFARSCMMSRAVYRTSRIDWMPDECAQLLERIAAPVRQKKPKKNIVARSNASFGVKSRFQLLNLDDGSTTKDSAADEDDDNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4X5</accession>
    <name>A0ABR3Z4X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774736" description="Peptidase S8/S53 domain-containing protein" evidence="6">
        <location>
            <begin position="27"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="203"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="457" mass="47798" checksum="B603B0866927DB7B" modified="2025-10-08" version="1">MAPLPSLSTLVAFLAASSTHIFSVQAASIDSNSGLDKRDRGPFTDVPTYKVLNPEVSEPIVGSYIAVYKSSVSDVAVQAHQAQVASTIARRNLERRDFVRKLKARGESDFDSLDLPTFANEDARVSSISIQGFRAITLDLADATVMNEIYDAPEIDYLEQNCAVHATEVATENNAPPGLSRISHAQPDPGSGYTYDNSAGYGISAYVLDTGIQLNHTDFQGRAIWGASINNKVYTDDQGHGTHAAGIIGGRNYGVAKNVELVAVKVLDSNGGATMNDVISGMAWVVANVTGRGISGRAVVSIPITGGKLKSANDAVTHVTDAGVVVVAAAGNNGDDSTSLISPASAPDAVTVSAINQTTDERPSWANYGPEVTVFAAGVDVVSTYIGESTTALAIISGTSVSVSHVAGLAAYLMKYEDITDPRAVKKRIIELGSLTGAKVLNNGPNTTNWIANNGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Y3</accession>
    <name>A0ABR3Z4Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ATG27</name>
        <name evidence="21" type="ORF">Sste5346_005429</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Preautophagosomal structure membrane</location>
            <topology evidence="3">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018939">
        <property type="entry name" value="Autophagy-rel_prot_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09451">
        <property type="entry name" value="ATG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0072">Autophagy</keyword>
    <keyword evidence="17" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19" id="KW-0732">Signal</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045990320" description="Autophagy-related protein 27" evidence="19">
        <location>
            <begin position="19"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="20">
        <location>
            <begin position="20"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1895282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="333" mass="36555" checksum="E9492CA0D8B0891A" modified="2025-10-08" version="1">MHFLLSLALAAAVQPATAMLACDRIVADKQIFDFSPLRGPHSVVTTLHTPPTEQNVTYTLDLCGPLKRKGDVPKGEECPNGSWACAIKRLRAADGTTSITQVIPLAGNLADQGGGSLDHKATRLKTADSHADAQQEGVRLVLQGGRYPLDGAVKDRQNQRVIVELLCDKEREGTEGEWLVGEYEGSSYTGSVNETLKKNGFSTREDHPGERQLTREGEDPALVFGGYEIHDADGTFGTLRLTWYTKYACESIADGRRDHWGFFTWFVILVFLGTASYLIFGSWLNYNRYGATGWDALPHSDTIRDAPSMLSDWIRRLINTLQGSGSRGGYSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5C2</accession>
    <name>A0ABR3Z5C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF8">
        <property type="entry name" value="UPF0047 PROTEIN C4A8.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="146" mass="16155" checksum="FEAD476247EE5DB9" modified="2025-10-08" version="1">MSWYQKTFSLPARSRGSYLITDAIVRELPAIKDYKVGILHLFIQHTSCALSLNENWDSDVRADMSDALDRIAPDAGPKGEALYRHDAEGPDDMPAHVKSALVGASVTIPISNGKLATGTWQGIWYLEFRAHKHTRHVVATIQGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z647</accession>
    <name>A0ABR3Z647_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="22"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="38376" checksum="B3334A86D85E05F1" modified="2025-10-08" version="1">MSSGKQTKFEGWLGLDSNSVKGQMKWGEFEPKKWEESDVDIQVSHCGICGSDLHTLQSGWRDTPYPCVVGHEIVGTAVRVGKDVKHIKEGDRVGVGAQGRSCLQKDCPECSTGMESYCSRGSVGTYGGIHPNDIGKSYGGYATYNRSNGHFVFKIPDALKSEHAAPMLCGGVTVYSPLKRHGAGPGKTVGIVGVGGLGHFGIIFAKALGADRVVGLSRKSDKREDALALGADEYIATDEDKDWPTKHARSLDLIVSTISSAKMPMSDYLKLLKVHGTFVQVGIPDGGELPNINAFTLIGGGIQVGGSAIGSPNEIREMLQLAADKGIKPWVQVRPLKDANAAVVDMDKGNARYRYVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6A8</accession>
    <name>A0ABR3Z6A8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ACF2_2</name>
        <name evidence="11" type="ORF">Sste5346_004904</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="9">
        <location>
            <begin position="38"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="10">
        <location>
            <begin position="386"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="751" mass="82496" checksum="60E4E29F98B945C4" modified="2025-10-08" version="1">MDLFPPVGAASSASGLPAAIPSRPDHPLKPVGTAPEVAHRPTGPLQTNKFYTNFLLHNQDLPTYLLPYSVHWTNGRGPTNCWGLTVSYATPDQRVFGPDTGPCNHPSKPSSYFYSPPILPNMVLDAAELNHTTVLTLDDATDMFCLIGLRPGSPQAPPAIQFPMVQGQGFFTALYHGARPILRTGMAITAVWDPYNGQGRDGGPLKPGVQRWVLQMNDGSTWLVYARSRPGAPPLAFRQTADGALEGKAGFYGSVQVARVLNPEQGWAAYDQAAGVFAVGVHLSGHTENDGVVGKYSFGFNKVDVTGDPAFLAQSPLLMFALPHHLASFDDRTRAAVQQQLFMETPVKGTARAVLADTWMMVEPALPVNMGFLPWDGQTRRTASTLSDGVRQMITQVARQELGQDMNAQCDLESAYFAGKALAKFALIVLCTSDLLGDKQAAADGLARLKAQFARFVENRQKHPLTYEGTWGGIVSTAAYTTGDAMADFGNSYYNDHHFHYGYFVFAGAVLGHLDPSWMQNRANAEYVDLLVRDYANPSRQDRQFPVFRSFDWYHGHSWASGVFPSMDGKNQESSSEDAMAIYAYKMWGAVKGDAAMEQRGNLMLSVLARSLQTYYYYSNGQKEMPAQFVGNQVGGIMFENKIDHTTFFGGDPELIHGIHMLPLLPCSPLCRPAPYVMQEWNDTFSQKRADKAQGGWRGVLYGNLATASPHAALDWFSQPGFKDDMLDQGASRTWYLCYAAVLIENLLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6I4</accession>
    <name>A0ABR3Z6I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="100"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="691" mass="76307" checksum="1E23DAC657021409" modified="2025-10-08" version="1">MAEVATQAAAAGAPALQPVATQTAPSQNAPVQTAPATASSKVHTKNTDETDKGGNVINDKGDNNTNNQPHSLPGHIKTRIATGKDKLTDKTERLRDKKSPPGGYDDTPLPTATGPTYTLKFTFHKATNLPVADLGNSSSDPFIRATLTVPAVATRHEEDPEMVHRTRTIHKTTEPAWDEEWVVAGVPASNSGFKLKCRLYDEDSTDHDDRLGNVTVEVPSFTGRNWAGLEHVVFDVKKRMGSKRAYLLKAASAAITGTKITPTLELSISVVGEDLHQEKDDKGARLYTVGPTGFVRHFSPMIGRITNTLVNRDERHDEGGPQQAQSSSMPPPDSHTSTTDKKEKSEVDEQKEKNEENAKEDAKDAKDDKNGGGTKKYDFQANEIQLAGPVPAQLYHRYVEFRPIIGRMFSSHGLRGRILNKALHKQHNRVYNFSRTTEYGSFPPCSDEASLQFLKLAHFDEGGRIFTYMISLDGVFRFTETGKEFGIDLLSKHTMHSDVATYIAFSGEFFIRRLAKPTGTSNPQPDTPTHPPTTPLEGGPPDEEPPTREPGYYQLIIDNDSGTYRPDKSMLPVLKEFLERNFPGLGIVCMHWEDETLQKMKSDQHESKKKEGGGMHLVLNRSPSNSSFSSSDESRLSDMDEEGQQHAEGGGGHGHRKTKKELAWDLLEDPTRIKDLHSAMQKHSIADDKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7A8</accession>
    <name>A0ABR3Z7A8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Esterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050583">
        <property type="entry name" value="Mycobacterial_A85_antigen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48098:SF1">
        <property type="entry name" value="DIACYLGLYCEROL ACYLTRANSFERASE_MYCOLYLTRANSFERASE AG85A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48098">
        <property type="entry name" value="ENTEROCHELIN ESTERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31712" checksum="0BE81393643A6126" modified="2025-10-08" version="1">MPDAHPKIPATPADFQRMNGEWIEPYNPETAPAGLKYALYDTKARGPGTQGNYWYALPDGYEADTSKTYPILIWLHGGTAQGSQGAPAVALYRTAMAAGLMPPTIIVLPQALPVGWYINSIDGKFPIEDIMVYDLIPHLDATFRTNGVRGLEGFSMGGYGAAHLGLKFSELFAGVSSIGPAILPSLANEPRERVWDTFRGDQGYYDQNHPAFLLREKKDVLRASGLRLRLLSGGDDTRLAEAIEVLSKLMDEVGVQHYRRDIVGAGHDFELILNGIGSDAAGFWKDAFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7J3</accession>
    <name>A0ABR3Z7J3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="285" mass="33013" checksum="BEB7EA7E85C4DB95" modified="2025-10-08" version="1">MPSFMSSAISTITFSSVGSTSEDGYNFVNSREFRNRLNSNSEYDNTAFARIYDYYTRVRDYEVHMQGIRDLNTKIKAGPPRDLSRAERCQYTVDLHNQKAEEVDLHRYYRRARQGKKVQEIPAAARDVRIDVFSTQSYGPEVWGDEPRPVWSKGSLDMKDFRNDQKTQCIDIYGRYFDSMEGIVPEAMAPVVEPEVFFTNESELVDADPSADPHDSHASTDAPTAEAIHREHQQAIAEQEREEICEAIDSLLEDRYGEPYAGVQELEGRRNWLRNEDWEELPLWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P0</accession>
    <name>A0ABR3Z8P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhoD-like phosphatase metallophosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF2">
        <property type="entry name" value="ALKALINE PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G03860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="1">
        <location>
            <begin position="287"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="631" mass="70275" checksum="6CB6E8DAD1CAC012" modified="2025-10-08" version="1">MVVQTKIAAATSILIRLGSYFFLRWALFPPVPPLIFALIAINIPSFVLSYLAEPQFDIVKEIDVVVADTAIVDEDGDGIEEEDVDITSSVSVQPRPLNGFRTLLLGFPSPSKFLSFLAVLTNVLLVALVADRLYSEHTITAEDLSFVRLGYVSHDEAKFLVREPDQSKMPVSIELRLRDAEPPFETPFWQTAGGTRWTDNSTDYTVALTVKLHHPTQRVYQWRTSNNHSGEFMSGPKPGQVPDLNNGSFTFVATSCMVSRVPYNPMDHPLAIPGTRYLAKVLPSLGAQFMLFLGDFVYVDVPRWWGKSVSDYRQKYRQVYASPDWNPIAQNLSWIHVLDDHEIANDWDKRKTGIYQSAVDPYHHYHTAVNPPLARQAGASGILRGARAGATYFEFSQGPASFFMLDTRTYRSSNSLPFDSANKTMLGADQLADFLAFLRRPEPRGIKWKIVASSVPFTKNWRINTRDTWGGFLAERQIILEAMWDAGLQGVGVVILSGDRHEFAATQFPPPAPNASDPSAPAARWPASVAVHEFSASPLSQFYSPVPSYFQWGNTGDVKMAYIYRGNSKFGAVTILPPTTNEAGETSPSQLQYRLFINGNEAWNTTIETPKGFEGPKALAKSFWGKLLGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Z6</accession>
    <name>A0ABR3Z8Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="45"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="520" mass="57083" checksum="8CC1275690AEFB10" modified="2025-10-08" version="1">MGIFNNAALARPEAHQQVPGTTMPKSPINTKKWWKYRNLRALNLWLLIPLLSIYAQGFDGSMMNGLQSVTNWQTYFGTPKGATLGIFNAANPIGGVIGTFLIAPVSDRWGRRVGLCFGAVLCCLGAALQGGATDIAMFVVSRGVIGCGSIIVAGCGAPYITEIAHPEQRSTATALFLTFYSVGSVTAGWCTFGTFRIDGSASWRIPSALQGLPSLIQIIFVWFVPESPRWLVSVGRNEEALAMLVKYHGEGDPQDPVVLFEYNEITNALEEEKEIARNTFIGSAKEFVSGAGNRKRVAVMVWAAICSQMSGNAFVSYYLSPILSSVGLTSDLQQTLINATSQMVSWFSALYFATLPAKVGRRTLFLWSITAMWIVVISITAGSAMFAQNNNNKAAGYAVVVFLYIFSPAYNLGWNGNLGLYIPEILPFHLRTKGLSFFYFVQLCFQILSTFAVPIGLENIHWRFYTIFVVWIMVEFVGVYLLFPETKGPSLEDIAYIFDGPPATKDYGNAEEKAVEEMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z906</accession>
    <name>A0ABR3Z906_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="693"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="790"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="716"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="805"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="817"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="954" mass="103252" checksum="B8F6D5FBF9B7C4AF" modified="2025-10-08" version="1">MSPSMSPDDNAAADNHDGSGARPDDNPNANIPRQKRLACLICRRRKLKCDGRRPSCSTCSRLGHQCAYDEVRKKSGPKRGYVKALEERLKQVEVMLKSQDAGPAGASAADALHGFTGGDARSASLKTGPGAAKTGKNGSISKTGNEQSGSSTTMGSSSGVGGAGDFSIPDPNSINLTGAAGRDLDTWQFNADSPQRPSSLDDFNFGGRMPGNMSGGIDSNPTWEIIQLNLEEPLPDQGIIDELTEVYFDKVHPSLPMIHKARYLAAMNLAANQRPPVCLRYAMWMSACTIMDKYSDLKDLFYQRARKYLEVDYMKGFGEHMISVAHCQTHVILASYEFKMMYFPRAWMSTGQAIRLAQMIGLHRLDGAGLEVKQCIPPPRDWTEKEERRRTFWMAFCEDRYASIGTGWPMTVDERDISTVLPSSEEAFEMSRPEASIPLHDAMCPSGIGQLTPFAGIILMACLFGRNLTHLHRPDNDDKDSDMNGEFWKRHRNLDHILLNTLLGLPDQLKLPAGLQNPNIVFTNMCIHTSTICLHQAAIFKAENNALDASVSPESKIRCINAANEIASIMRMVSHMDLSTMNPFISFCLYVAARVFVQYLKSRPDEGRVVDSLRFLLTAMSALKRRNPLTESFLVQLDVDLEALGERIPQLKSAFPMSYDSPSSGVPQGAISRPGAVCEDGAVDGILSFQKEYSKSDNASSSQENADDNAKDRVSDTGSASMNSNDSRFRPKNVDGSAPATSSNWVFPESRLPTRDRSNDHSPMFNIPTNGFPDPTVNILTANGRPMGFVDEIHDMSTSPGDGLSSRPTPNSSSASEGRQNLAPPQQQTGMHSAGSSFDTSPVSPPRVIVGGQQPTQVDRGASGGYFSTANGGAADYSTGQPGSAAAAAVGMNGGGAGLGGLMSADPNSNDYMISEGWNMNGQTAMTPVSEGVLRTIINMGPMETMDLGWGSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Y4</accession>
    <name>A0ABR3Z9Y4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="878"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="963"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1050" mass="116284" checksum="D574D7BED1C5C9EA" modified="2025-10-08" version="1">MAHFAFTPDTVESTSTPASDAPSASSPITPRDTHPGYSPGAIYSRSTGQPSPSARSIHSLHSAAETSSGKRRLGLLEYPTTHEDLQFCRDARERFKVLVRDNPSATPVDLEQAALSSLDQLRTIFDDMCHIPPPECVFYQWSYRQSHGADAETSGADVFHLLNSHCYMFDFDPQDNNTAFPIPDRDQVMAVLSLVGCHLTSLMLAFGLRRGLRRTSTEGREIFWMIYNTLMDLASNVFEDFLRAQPFLDRSVQLMSTVRAQRGATGALAYSGVFPTRAEVSYAMEIYATETRQAAEKAGAGLSPAATEASPLSFAMHRLDRLFQGIQSPAENSVATEQPQPQPQQFLEPSPMLLAQNFVGVSEPVYPVNTFPLSAPPHPSQQQSSARTNQDDADVQEDHMNPTNAPMMTARILRRPPTTCPAFTPVEVTIRPYSPYPMCDTPSSVNGPVLPDGGVPLESTTVDDTRPSGLHTSSPQPVSEADKDAPQPPTPPANSVGTTLEEPTANLGQQQAQRRVPPLAAINCNDVTELLQEENVLHEKFIDFVARFHDNVSETGARSLEKLVLQHLDLVYHRQQQQCRRELAARLRVYRRTPYYSHDQQQSTSNDTNRSTILGGLHQTSRRSTTTCNQDGTVDSRHSEGEGYVYMDISSTDNPTSHAGRDFGNVFDAPPAPDPYAHRIHNQQGRLLEQSRQTYRQDTSPPQVPPPPPPYEPASQRLQPTIGPPIPYNLALPSLDQADIIAPQPLRPTLPALVIPPPVAIPRTLVGPHLRGGARNEGYATLLEALNSLPPAPLAEQNEMVRQQYERYHQQQQYQLELQRQSQKQDSIMQAYQEQKLQHQRQILAQQALIQREQLAQLEYMQHQHQIHLLKSLHTHVVQQVEAQRRSGRESVPTPNHSPTEDGDEDAGFNAYTSCVDDESDAASNTCDDDQEEDDYPSVPILSLGYEDDHDVSYIPAFVRSRSVDNSSSGHRPENLDPPQYTVSRNQPLFGDLTGLPPSPATTSSSASSASPLRTAMTNARNGFENHEHRDTVGHNTAAHDADDDAILYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB39</accession>
    <name>A0ABR3ZB39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="997" mass="110826" checksum="14BEB3A3396F8A20" modified="2025-10-08" version="1">MEINNNEIIEIYLSSIWEYHAAGVERVLKALRDKNPSGRYSFEPELSWFKASCETRDVRTVQNIFKEVHDEMEKVMGGQRVPTDNEWLKLPIASELERGAATKKTIDHMCPIAFDRFPFRKVWARIKHETPDHISVHKLLDEDARLSVMKETDTHVAIDTANARLIYIGGPTKQAVSNASKMLDNLFEKFVCVAPPPKHLLYAEVDGPYNVDARYMAHVNETILTSTIFDPSQFPDAVLDHMFQKTFAKGVCLRMCDFDHFKRIAVSVFGPRSQPIFFDPARKWPLWFKRAEYTPKALGVTAPKEEPAAVPVKKPVEEPVQESVEIVPQGNELVPFKDPETKEHRKDKGKEVARVEELAQEFDLLGLDKPDPAPTAAATAAPDAAPTSGFKSESELEEAKDKPEPAPPVKMPQMPSSYQSDKHNYEMKLLWDFMNSSKKDAADTSSKPAAKVDVKAKGSKEAKEAKEAKEANAKKTDKSDNSVKQTIKEEPKDGPADEMALITFRDENKAPATFAVPGSAAPASKTEDIMLIQFDAPASRPVTPASRPVTPTPSRQRQLVTVPHGNSRSAVPRGPALSKALVRRSTFATGLCHSMGRLMADLPYCRGRIRMQVDLGRVYIMDAHPEGLAFNMPGEEASGWPHTEITTRMDTICVSPESIVFTKALTLFANDMESVLGLNSKLVSNDLLGDIGGNSPPPAADATTANTTARRSDWSVPITPDWAFHERRTIYEFKCQRVYMNGSGVIKAQSPFVIEIDGTEPGGFIYGIRSVEDTRPPIWIHCIRRHWDARVSVSYNKTDKLEEEYGQFARDLLRTLVVPPGPITSPRFQFAYDHSEVKTPDKNQTFSTVVLSARVRNVGRFQSTDKQSFLDISWNWLMALAKRPAREKSSTGVVYASPAADHPARGVFSSWYEASVSSAVAEESFKENETMPVGGLAAWGTKGIAAREEMYEAAFGPALKLVRNMDGVGVLVDNGQGHQWTPPVKASQVALAVQKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBF0</accession>
    <name>A0ABR3ZBF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-hydroxyacetophenone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="73603" checksum="A2F5CCC2C475046E" modified="2025-10-08" version="1">MGSISSTDPAAPVTDEFLRSAIDKSNLNALRLALLQVTGDQDLAKMRTRRHAVRGGAMYTHVLSEEDTPALKEKAFAYLSQRKSTDPMPEPPTKEETRKLVDVFGDEKVSDREFEYDYEELAFAEFPRTANWTDGKKPPQDQISKFKVIVIGGGISGLAAAVQFKRLGINFEVIERQHDIGGTWLLNTYPDARVDVSSFLFQFKFIKGYHWSEYFATAGETQKYLAYVAEKFQVRDRFSFNREVTSCIWQEDTSEWELTIKHKDGMVDVVRCNAVVSGSGLFSTPKLPDIPGINEFKANGGSVFHTANWDHSVDYAGKKVALLGTGSTGTQLASAVAAKAGTLTVYQRTPNWIMNMEGYRAKIDDHVRYVFDNMPYYWNWFCYSAHATTQQLQYMQSYDREWQAKGGTINERNDLVRKALIQYIEKKSEGVPGLKEKLTPSYAPLVRRLVVDNGFYDTLRRDNVELVTDNISGFTKNGIKSDDGVERRLDVVVLGTGFKTSKYFWPCNYVGRDGATMEEIWKKDGPRSYLGMTIPGFPNFFILYGPNHQPRSGAFYSWGEIWMRYISQCIINLIENDKKSMDCRKDVFEEYNGRLDEACKELIWESEGSSYYVNELGRQSVNAPWHTADYHRMVRTPNFADYDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC56</accession>
    <name>A0ABR3ZC56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="64"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="502" mass="54997" checksum="853267896F472474" modified="2025-10-08" version="1">MGAVLSWLRKHSGNKPEPTTNNNTIKTSKNSTTITADDTVVDIAGKMATDTVTSSGSSSDGRLTIIIVGAGLGGLGAAISCAMGGHSVRVIEQAKEISEIGAGLQITPNGSRLLQHWQVPEAFWKTVAEPTDLFVHRYSGEVLYRETDFNTRQRTKYGAPFVDVHRADLQQALYKRALALGVVFSLDERVVALDVAGRTDASLTTASGKSFTADLVIGADGLWSQCRKTFLNDAPRSQPIPTGDLAYRIVLTLDEISDEDLREWVRKPTVHFWIGPGAHAVGYSLRGGEMYNIVLLVPDNLPDQVSKEKASVQEMNELFSSWDPTLKRFLGYVDSVDKWKLMHMEELPHWVNDEANLVFLGDACHPMLPYLAQGANSSLEDGAVLGTLLSHVKEKSQLKTALHSYEAVRKQRGEAIVRETFNQRADFHMLNGDKQVFRDEALRAGPNWDTHAAFPSRWNCPKVQPWLYGYDAVAEAEKAVASQGKANVSSGPSGSALPHSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC88</accession>
    <name>A0ABR3ZC88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003774</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30699" checksum="4B57DA1C9A49BB31" modified="2025-10-08" version="1">MSKDATKDNGEYDRLPLGDDDPSATEVDNFERKPTVIRRSWIFHRFIQVVIVFWATVLLAGAVAILSQHIVNRQLAAATSTCVCAPHDQYRVAEDFTSNVPQFGTTLLQFDETMGFTFDPRTATTADVEDVLHHWASLSPIGDGFILSNNSRELLPEPKWIAGAGEGLHNLAVYHQMHCLYRLMMAYNDAVLGTPTDVDHARHCFNYIRQTIMCVADTTLEGVNPDSERPETARVGAHRVCKDYSQVQAWAQAHRRQPVPGYNPHPHKHEGHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ7</accession>
    <name>A0ABR3ZCQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GED domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF131">
        <property type="entry name" value="GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="892"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="585"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1010" mass="112920" checksum="538213581AE08C21" modified="2025-10-08" version="1">MTASTVSSRSLTESSAMRLNVKQEPGGYPLTGVTMSAHPAAHSQQNSRFARSGAPSIDTRIGRQTVTDSHGGEGVDDDDTPILMEVRKIKTQPPESILDRLDAPHAFPAHANQGHPNVSFVSHGFTAIGDKVKELNDTLGELQSLGIQHVTSLPELVLVGDQSAGKSSLMSGFSDIYLPRSEGACTRCPVHIRLSGAQAGGPWACRISLQQDYDYRPPQGVTRANPFGPWFEKRRDIKDFANLNDPSKIEETLRWAQIATLNPKHDHSLYKPGTGEYWKRYHPLSSDGGDAFRNEAAFSPNTVALDISAPGLADLSFYDLPGVFTSAKQDEDQYLVKVVRNLTAKYISHKQAIILWAVPMNVDSETSSTFSIIREQKAQNRTIGIMTKADLLPPNPTAAAQWMAMLRGEQHKVGHGYFMTARPIVTEDLLPNEMVQSSHRDPSRPADELERQGAFEEAFFNKQLPGMANQEWRDCFRDFEDRCGVNRLVAFMSQQLGHEFAKCLPEIKEKVSMKLLDVNYELAQLPDMPENPELEIRRSLVAFTSQVRSIVDGPQLMPLLNGIIQQFQEDIANLKPKYKVKVESFSNGPAGSGHNRPVTDNNGRIDLTLGDNDDVLSANGGGSPAPGFASVPPSGASMPRRRQHSIFLDGQADITGPSTPSKRARGINGSVKQEDQSEHGGDSPAFGAGSRRVLFSRPGQQGADQHKQARSLQMVRDIIDARMKPGMPNIVTEDIYNSLSMEAIRPWMDPLLQMLDRVYNLLDAKLHELLSVALSNLRKRLIYKHASCALKKFLVDRMTEVQTTLLQHYQLETRKYYTLDREALARNEEAERIVLTRHRHHYRMVAYLGEQRGRERSIPKDWEAMSDDERTREKAIMNQELAKLGPDEYTRELGVCANVRGYYRTAATRFVDTCTMHISSGLLPDVTDQLSKSYLDNQLGVFDRTTPQTFLDLMDEDETTAQKRASLKDDRNRFQLTMESIQRLENSSQYSQEQPTQPQSQVHVQVDGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDT6</accession>
    <name>A0ABR3ZDT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tyrosyl-DNA phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003469</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="68622" checksum="7FE61FA535CEF69E" modified="2025-10-08" version="1">MSAPVSPPRKRRRQEDKLDVPVLAPDDVAADAAVKDEKGPETMPSHPALRSPFHLTAIYDLPASANVDTLTVRDVFGDPRVVECWEFNFLHDLDFLMGAFDNGALQRGLDVHVVHGFWKREDPRREHLETAAREYLKDNNQGGGSITLHTAFMPEPFGTHHTKMAVLFRSDDTAQIIIHTANMIPHDWRNMTQAVWRSPLLPLLKDGTVGEERKEESGIGLRFKHDFLNYLRSYNQRRSVCGPLVETLQRYDFSAVRAVLIGSVPGRHHVPFPGEEEAEEQERKNLKSGDESRLAHTRWGWLAMKRALDDVPLRPEAKTTEIVIQVSSIATLGGTDAWLQKTLFPALSGGVASRDSVPASPKQAASFGPLRWTQERQPPKPQFRIMFPTADEIRRSLEGYVSGSSIHAKIQSPQQQKQLAYMRPMLCHWANDSEDGEIITSTTTGPSRGVGDAKRRRAAPHVKTYVRYSNSNGDCYIDWALCTSANLSKQAWGEARSAGGEMRIASYELGVLVWPELLTGVRDAGMQPVFGRDDFVVDARSTKEPTALVASSSSAPVPNNDVVSAKVTVENASAPPVVPLRIPYSLPIQRYTANEIPWVTSLPHSEPDWRGMTARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDT8</accession>
    <name>A0ABR3ZDT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">BUD32</name>
        <name evidence="18" type="ORF">Sste5346_003241</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="30"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1898831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="287" mass="31140" checksum="4E51F593B93651E6" modified="2025-10-08" version="1">MTAPEQPPARQAGAFPLPRILTYQPTSSTSPPPTLVAQGAEARVYRTTYLDANRPCALKYRPPKPYRHPVLDARLTKQRILAEARILHKCRREGVPVPALYAVDVEEDGADGKTNGGSLLTEWIEGGPVRARLNTWLATIPVVAEAEADLEGLRNAGLLTLLQRMGAAVGSLHKVGIVHGDLTTSNLMLRPAAAASTANEARTEEGATLDGDIVIIDFGLASQSSSDEDRAVDLYVLERAFGSTHPRAEALFDEVIKAYGKAFKQSVPVLRKLEDVRMRGRKRSMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE04</accession>
    <name>A0ABR3ZE04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003326</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="480"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="209"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="820"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="826"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="873" mass="98371" checksum="A9953FAF9EF80396" modified="2025-10-08" version="1">MKASRRIDRSVCGAVLSARVPSFPHLLPQTVTTGPAGSRPQPSRCIHDQRRKPQNGRPRTANNWITATAAADPASGTLLPMLFPPAWSSNSSWKRPSAHKAMHFLESACHRVERITAPSSSRSSKLEHHSRANHSSAAAARSQPSADEFDDILNQVENGIHESSSTPVAAETQKRVEDIYDVFDETDYNERQSKHIPSSATGRIDPEEFDEFFGQNGHSHGERQNKPKAQAKNNNRTNRRSNRIYKKNDDRDSGNSNINTFYDSSFNCSDPITHPTSLDTEASRPRKKELTKDELRSIVDPPMDGDSVQEHLTFIQDPYLRRYAPPDDRPDVRITEKNDDHMFPTWTDAADFDKDTQKTLRDLDHAVMTRLRQPFNVSAEAVYDIYRKLPGTRMSYVPTTLRHHMLRSLNMDARKTAKAMLRFFAVIADVKDSGFPLLRAEYNAAMSFASRYVGWTTAAEAESAVNLWREMEQVAHIPGNEVTFNILFDVASKAGNFTLAELAYDEMTKRGLRFNRYHAVSLIHFFGLKMDGDGVRAAYREMVDAGEMIDVVVLNCVIASFLRCGEEDAAERVYARMHPRYRQRLQASADAEAKLVSAETAASAAAASSTSTWHHQYPPSRGSFVLSSASSPSSSHPKETDYNSQKVLTQVLMMLAKVNRKNKDTRAGFQYLMPIRPDLGTYRILINHYATRLGSLPAVTRLLDDMKILRIPLHGAIFQALFCGFARHGGAIGVDCDWSLERLRSIWAALLKALDDETEGLYISPWLLMWVLRAFDRCGSPEMVFKAYNSLTSRWDPDEIQSEFVLNILHSLLKKRKPMHTWTGGDGDKDHEKKERKGAFGSGRKASHITKDFVPAIKQERSILGQLGRQQFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL3</accession>
    <name>A0ABR3ZEL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit DUO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein DUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Sste5346_003445</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DUO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013960">
        <property type="entry name" value="DASH_Duo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08651">
        <property type="entry name" value="DASH_Duo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="149"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="200"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1898541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="271" mass="29467" checksum="F0E3F58EB6CF0468" modified="2025-10-08" version="1">MDSSDLFSSSPVQEPAYYTRDTRDERPKTPKTPTDKTPQRTPPTHQQQPTHPFDAEEAREAALQRELEGVRQINKVIEGVIGTLEQSRGNMSTVAQTVGNASTLLNTWTRLLSQTEHNQRLLLDPQWQGATQDLQAFEAEALQRQQEAERRAAEAQRKRDEAKRKAEEEERRRLAAPSASSSSTRGYSSTGRGLRGGVRIGTTRGVGRTTYGTTSTRGGRIGTTAPGTGSTTTFSGLTRSNSTSVSGNARSGSNIGRGLPRGTRASGRGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFM4</accession>
    <name>A0ABR3ZFM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MCA1_1</name>
        <name evidence="7" type="ORF">Sste5346_003029</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="121"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="416" mass="45793" checksum="4B27797EF319860E" modified="2025-10-08" version="1">MSGYPGQNYGPYGAPPPGAFPPQGYYPPPQQFNGYIPPGPGGPAYGYHQPPPQPYGYNQPPPQQNYSGAPFNGGQQQFGGPRQSNNAFVDPNMHKPPQTPQQFGNGAPNGYNFQYSQCTGRRKALLIGINYFGQRGQLRGCINDVRNMSSYLVEHFGYKREDMVILTDDQQNPMSQPTKENILRAMHWLVKDARPNDSLFFHYSGHGGQTRDLDGDEDDGYDEVIYPVDFRTHSHITDDEMHRIMVRPLTAGVRLTAIFDSCHSGTALDLPYIYSTQGILKEPNLAKEAGQGLLNVISSYSQGDLGGVAHNIMGFFKKATGGDEAHARTLATKTSPADVIMLSGSKDDQTSADATIASQATGAMSWAFISSLKKNPQQSYVQLLNSIRDELSTRYTQKPQLSSSHPLEDTNLLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG12</accession>
    <name>A0ABR3ZG12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4 15">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CHO1</name>
        <name evidence="18" type="ORF">Sste5346_003034</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="15">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15 16">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4 15"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016271">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000852">
        <property type="entry name" value="Phosphatidylserine_synth_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 15" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1899112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="233" mass="25341" checksum="7B786B7765D65EB9" modified="2025-10-08" version="1">MANGSSSSAPAELSQPADKQKILLSTDPGHFSLIRALHMADFITELNGACGILSIFSSLRYCIDPTSRTNLWFALALLPLGFFFDAMDGKVARWRKKSSMMGQELDSLADLISFGVAPAAVAFSIGIRSTIDHVLLAFFVLCGLTRLARFNVTTAVIPKDKTGKASYFEGTPIPTSLGLDALMAYWVSQDWILDNLPLGTWFAGTAYELHPIALLFVLHGCLMTSKTIHIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG73</accession>
    <name>A0ABR3ZG73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GRC3</name>
        <name evidence="11" type="ORF">Sste5346_003114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Polynucleotide 5'-kinase involved in rRNA processing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="10">
        <location>
            <begin position="256"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="546"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="664"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="672"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="746" mass="81118" checksum="FD6ACADAA3A10D34" modified="2025-10-08" version="1">MEPRKKRKVEPGPPPAPPKSARQRMLEQKEAAAREAQAALEKAAAEAKAEQSQADETQDAQPAVTEAVAVLPVQVSVENEAPKIQAEVTVAAAPVAAPELKPVEPPVVQIKSNATRLVIIGSYGLTIKCGTMTVAGATLRASEKTYWVHAPRCYALPVLRCTDDATIMLQPHPAAAALRQLGKLSPMFSRLWNEPPIDSSKKEFNATFQILYTSDDDVLPSRDITAPPEWYKLIAELTSPKKGAPKPGQQVLFVCGPKSSGKSTFSRLLANRLITKEVVSAGKQTKKWTTPSVAVLDIDPGQPEFGTPGSLSLVHVHEPNFQPPFCHPYVASDNSQGNKLLRAHELASVSPATDPEHYIECVLDLYSLYHRDLRNRCPLVVNTPGWIQGTGLEILTELLKRMRPSHVIYMSREGPDDTVVGLKSAYQNVPFVELPSQPGDLKVRTPAQLRTIQTMSYIHLDASSPPSKATSLQKPPIRPYASWLASPVSAIRPWVVPYTGPNSGILGVMCYDSQPPTDLVADTINGTMVSIVVIENMTAFRTMDEATDGSSTEMEVDAEDGDGTSNSTPRRLPPFVRSPEGIPYILNPDDRKLDPRHSYKLGVALVRGIDTRNKELHLLTPLRAGEAIDQVMQQDGVGVVLVSGKFDSPTWAYTEDMFLQSARKETKGAGEATDDVSGEDSDGDESDAGEDGTDTESAAIERGKQPPSDIPWVETLHGGQKRDIGSRVWRVRRDLGRNNNSNGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGH9</accession>
    <name>A0ABR3ZGH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CKB1</name>
        <name evidence="5" type="ORF">Sste5346_002689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="281"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="372" mass="40852" checksum="42456D8607395374" modified="2025-10-08" version="1">MSTSSGTPETWIASFCSLLGHEYFAEVSEEFIEDDFNLTGLQSQVQLYKEALEMILDVEPEEDEDEEEEEEDDEEGETGEERMRHAGERRNHSRMPSDLSMIEGSAELLYGLIHQRFICSRAGIQQMSEKYELSHFGVCPRTYCNLARTLPVGLSDIPGEDTVKLFCPSCLDVYVPPNSRFQTVDGAFFGRTFGALFLLTFPEYDLTKNGVEALTTVSSLYAGQSGGSPTVNGIYARNTAPGLGHGKIFEPKIYGFRVSERARSGPRMQWLRSKPDDIADLDETRKHNEAEQRRIGTDSDGDVRDSDHDASNAHVAVSTGAAAAGVRRTTTGSGSASQQLAPNAEGSTDAQLRQHQNGSPMTVDANGVESEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGL2</accession>
    <name>A0ABR3ZGL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TRP4</name>
        <name evidence="5" type="ORF">Sste5346_002930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="261"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="434" mass="46522" checksum="DC38B56BDAEF6334" modified="2025-10-08" version="1">MASQQAGAAPAADEVVDIKPLLSRLWPLPEAGTPLADDIADAVALFFTNRVSDVQAGSLLMCLHFTGLDRQADVMAACADRMRKAAARVDPAPLLKIAREKSLKRGKYNGGLCDIVGTGGDSHNTFNVSTASSIVASAYLRLAKHGNRASTSKSGSADLLANLKHSGDIENESTDLVANLNFIEPATLQAIYSTTNYAFLFAPVFHPGMRYVAAIRKQLPWRTLFNLLGPLANPVDIRETPESESPLEARIIGVARRELGPVFAEALRMTGARKAMIVCGAEELDEISIAGPTFCWYLHEDASGKEVVIDHFQLTPADFGVASCPLSDVSPGKSPAENAATMTSILQNQRPADDPLLSFVFINTAALMVVAGLTEPEDSSAPEDPEVITERGPGGLRWKEGVRQARLAVSSGEARKQWKLFVEATNQIKPTTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGX1</accession>
    <name>A0ABR3ZGX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alcohol dehydrogenase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF2">
        <property type="entry name" value="GROES-LIKE ZINC-BINDING ALCOHOL DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="149"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="305" mass="32598" checksum="EA578E8941ED9833" modified="2025-10-08" version="1">MKASATQAIVCHDPVEGKRQWILEPISIVTKVQPGDAVLLSFAFCTQCHNCQFGAPGYCHKFTELNFVGNKEAFPGSKDEPSKAIGGSFFGQSSLAQHTRVQETSMVKVTHLVNSREELSMFAPLGCGIQTGAGTITQLGQAGPNNKSAIMAAKLTGCRNIIGIDRVASRLELAKILGATHVVNTSELSGTLVDEIRNITGGSGSTITVDATGATPLIQQGVEFTPNQGKMILLGVAPMDAGFEVQIIPYMVTGKQLMGSMEGGVYPEQESLADRPIFQLITVKDYLKAVRDMEDGVTIKPILLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIW4</accession>
    <name>A0ABR3ZIW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="56988" checksum="151B4FAA844DAC8E" modified="2025-10-08" version="1">MAASMPWLPFPFGPQIPVTPPPDHQSFSLAQGPPPLSPNLLKSFTQEIYGHGNSLLSNSLSGGLSSGLSGLGGGLKGSGLQGRNMMMANSQQRPLPGSVAAGVNGSTKHVFPPPPPPLQRQQHQQIKTEPKEPPATTAPPSTTTAPSASDKTAADGSTTTGAATTETKATTASAAPSEGGPLSASDPRYLAMASRIAAYYHQRCQAVANFQQQRCQAWANMQRQKSQEMTQAAMLVVAWYIRDRIQRRRRREKRQFRRGLAAKAAGNNNGVVKGGKGVRRAGSGGPVRVTKGEAVRKWVLQVPEGSTALSPNTPGARDRPADPDEVSFDIDRDTVSDKDMRLYNVADNLIKSQLARIDVPMMGALSFDASESESDSEEEEEGDEEDEGDDVDNDDDEPVGPGAHNDEDDIMVNYEERGAPIEAVAVGVEAMITDATAKTAVRAGLGAGAGAAPRSACKHEHHPDDDEEYYMEDDDDYDFEDDDDEEFEEEDYEDEDGECGDGDDDGQQVSELVHHGTGAGSGSSGSRQQTSSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIZ8</accession>
    <name>A0ABR3ZIZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pua rna binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.10">
        <property type="entry name" value="Trypsin Inhibitor V, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600:SF1">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="8868" checksum="9777D8AD7C56F408" modified="2025-10-08" version="1">MPLVVPGVTANNLGDSKTQEWMSKLMGKTLTDGDSSETAFSKKDLPKNARVIPYGATATNDVEPDRLNVSLNEDGTVAKVHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ39</accession>
    <name>A0ABR3ZJ39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit C</fullName>
            <shortName evidence="4">eIF3c</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 93 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF3 p93</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Translation initiation factor eIF3, p93 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">NIP1</name>
        <name evidence="7" type="ORF">Sste5346_002371</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03002">
        <property type="entry name" value="eIF3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027516">
        <property type="entry name" value="EIF3C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008905">
        <property type="entry name" value="EIF3C_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058999">
        <property type="entry name" value="EIF3CL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05470">
        <property type="entry name" value="eIF-3c_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26569">
        <property type="entry name" value="EIF3CL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="611"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="803"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="828"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="871" mass="97794" checksum="F17512F6159096CD" modified="2025-10-08" version="1">MAATRFFRSGNDSSSESSSDEEELYSEEEEELDEVDDDDDDDDDDDDDDDDDDDSDSDSDSDSDKPRGANAFLLDADSDSGSDEEETTAKVKSAKDKRFDELDATITAIENGQKINDWGSISTEFDKLNRQAEKLRQGSKAPKLYIKAVADLEDFLNESISMQKVSLKKMNATSARGLNAVKQRIRKVTKEYQGQIDEYRADKDDFMESDEEEAAPAPRRPGVAQVQFAPSADEGDDEGFSTVVGKGGRVVQFTPEGIFKQLRTIMETRGKKNTDRPEQIKIMEKLNEIAVTPYQQIRVLLTLVSARFDLGSGAASFMPLDHWKAAEKELGQLFKILEKNKEYIVIEHAEEWDDDDKPPTLEAGQKYIKIPGSIVSYVERLDDELVRSLQNIDPHTSEYIDRLQDEGALYNTIVLGQLYYETLRKDASREIPQESLNRIVMRRLEHIYFKPAQVVKILEENSWKAVTSGLDSTISPRAESSEPSGLLNVLCGYLFANSEGIIRARAMLCQIYFLALHDDYYRARDMMLMSHLQETINSFDVQSQILYNRTLVQVGLCAFRKGLVYDAQNTLQEICGSGRQKELLAQGVMIQRYSQVTPEQERIEKQRQLPFHMHINLELLECVYLTCSMLLEIPLLAQTGSSPDIKKRIISKTYRRMLEYHERQIFTGPPENTRDHVMQASKTLAAGEWKKAIEFIHSIKIWELMPQSDSIKAMLAKQIQEEGVRTFLFTYAPFYDTLALETLSSMFELETHKISAIISKMISHEELAAALDQVKQTVIFRKGVELSRLQSLALTLSDKASALTESNERTLEQRTQGSANAFDRQGGRGRGGGRGGGARGGRGGARGGGNTQRQAGGTQFTGGALGAAVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK66</accession>
    <name>A0ABR3ZK66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="274"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37695" checksum="FD38324B897C1E94" modified="2025-10-08" version="1">MSCHPPFATAGLRRSGPRPAQPRSFKDYKNEEMISLSKALAANDLSVVDALISRYDALSRMKPRIIPDNPLAARTLAKMEALTAQYKTSGPWTGNIYHIAPWVAPIMHDAIEIDNAEFTKGLLERGMLLHGSYVKNAIEVHAMRCLTLFLQRGHDLNKPQGKTRPPVWAYCVTDWFMLQWLLDHGADLNTCAPCDGTTPMSYVVQFCPPEIIHTLLEDPRGLVDVNKSEVLHYALARTTDVLPVLVMLLDHGAPINAGLYANNLGAQNMFFFMARGPPLHKAADEGNLDAVRFLLSRHADVMICDTQGHTALYYAQKNGHTAIIELLKSAMADFKVQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLA9</accession>
    <name>A0ABR3ZLA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="6">
        <location>
            <begin position="110"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="35603" checksum="0130C9BFBD2B0A28" modified="2025-10-08" version="1">MISPSPPPQEDGTTAPAVEAGEGQQSPMSHASSETAAAVPPQSTETEAGVEAAPANGKRSAPTSPDRMEEDTTEDAAASANMNGQEKPTEDEPSDDAEAAKPPAKKRTICGVCNKEPSKYKCPRCTLAYCSVACNRIHRDNHPPDAPAEEKKSTLPSASSVSSLPPKPTPPPHPFQVLDDAPELKYLFEKYPTLPDRLKKIYEATQPPAARGSGSANKPNIPGLPARLPNNHSKGGRGGRNNNEIWTKEKGLREGQKALRRARVDPSEEGDAVRAYCELVTHLLAREAEGATSATSTDGANIPNGGGGDVTALVREELADEANQVIKKLLDTEGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLF6</accession>
    <name>A0ABR3ZLF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ELP1</name>
        <name evidence="12" type="ORF">Sste5346_001908</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="7">
        <location>
            <begin position="1"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="8">
        <location>
            <begin position="412"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="10">
        <location>
            <begin position="703"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="9">
        <location>
            <begin position="925"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="11">
        <location>
            <begin position="1097"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1183"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1288"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1183"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1201"/>
            <end position="1217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1335" mass="146423" checksum="7B76FC1BD8F496CF" modified="2025-10-08" version="1">MRNLRNIRYDVCHDATGASAVCLDAGTDEVIAAFGPSEDEPKVRLARIVDHSELISHDIASWDALSPIPDLAVDHIVSLHYFGDLATVCVIMAGGDIVMVREENAGSHEPVHIEIVGSVHPGIAAARWSPDEEVLALVTTGGNLILMSRGFETIGETPLTSADLAASKHVSVGWGKKETQFKGRGAAKAMRDPTIPEIIDYGTLSSEDDTSAVTISWRGDGEYVAVNAVETIEGIEEANASDTKRRRVIRVYNREGVLDSASEPVDGLESYLSWRPSGNLLATVQRKSTGSSPVLFNIIFFERNGLRHGQFELRLPSTGTAAGPVSLDWNTDSTVLAVTYESVVQFWTMGNYHWYLKQEVVTSSQKPLTVWHPEKPLRLVTSTFNGLVSAEYIFSTSRGALTPPYDHGSVTVIDGKTLKLTPLRATNMPPPMSLFELSISLPAVDAAFSPKDDAVAVLTSAGLEMFSWEWHATAKRPPPPTLVASVSFADDANLVGFVPLQVAFVQGSQYTVYVLGWDAMSQTQILSYVFDREAGQLSPAGPVPVARGSILATARQGHDLYTQDASGSLTQLNAERLSSFPFHAKLPNLLPWVEVVDSGETGPQFAIGLSRNGHLYASERQLTKNCTSFVVTDDHLVFTTSNHLLKFVHLTDVHELEIPLDDPEVDERCRSIEQGARLVTSIPSNLCVVLQMPRGNLETIFPRAMVVAGIRKLIDALDYGKAFSFCRSQRVDMNILYDHKPQQFLANVDRFLDQLKDVTSIDLFLSSLKEEDVAQTMYKDTKKINNPTPFGLPQVVPPTPAPAPTSSTKVSTVCDAALAGLASRKKTNLQNIITAHVSKLPPAIDDGLAVVAQLLHDNETAAARAVSAKAVEHICFLVDVNQLYDHALGLYDLDLTMAIAQQSQRDPKEYVPFIRTLHEMAPIWRKFKIDEHLERHEKALGHLADYDDFNEFLQYTNKHRLYKKALGIYRYNAERLAAITNAYAKYLVTESKYREAGLAYESLQNFAKATSCYQSAGVACWQECLFAAQNQTPPLSGDVLSELASNLAEALLEARDYTAAAKIQLEYLDSVEGVRTLCKAYEFAEAMRVAARFRRPDLLQTHVDPGLGDALSSSTELLADCRSQLKAQVPRILELRQKALEDPLGFYEGERMGGEDVPDDVSIAASSRISTSASLFTRYSTGTAATGKTGQTGGTTTTQQHRNRKKREEKKRARGRKGTVYEQEYLINSVRRLIERVERARPEVQRLVVGLIRRDMAERARAIEALMAELIEACQAAICEVWQQSSVPGAQGAPTTAVESGASGATQENGDMSINTNNSNAAPVIVAFERLSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP99</accession>
    <name>A0ABR3ZP99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Integral membrane bound transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF1">
        <property type="entry name" value="DUF2421 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="750"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="774"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="825"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="7">
        <location>
            <begin position="774"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="423"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1102"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1102"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1121"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1196" mass="130347" checksum="B08776082AEBB32B" modified="2025-10-08" version="1">MSSSGSLSDEDEDDPSFFSAPGFIARFESAGRATRDGLGRFRSWLDSPKGRGVIKCTVAYTIASLWTFWPPLSNLLGRLDGKHLVATITVYFHPARTAGSMIEATVIGVVAIAYAEIISILSMATSVLFGSVIGWVTFAYMVVLFFFIGMAFGFIGWVKQRLNHPSVNVGCTLASLAIITVVTKENATYSSVFSNDKVSQVVKTLFFGISTTAAVSLLLWRVSARALLRESFTQASTSLGDMLAMIAHGFLSGAEDELTVSAEYRTAVSNWTSAHAQMTKNLKEAKYEHFAVGHASLYQFEKLVYKSMETLALSIGGLRSAANTQFELLRESAAAAAAGTMSDSAPVTAGIPTGSVPPAMSLLDQFLASPRSATFSPSTSPSPALGSVATSSSSSSTSPSARPQLYRASSSFQRSGRLAVLSAIDEASDESSEDRPDAPLITQYSDNDTGGLMNAQPSPRPVNHMPLVDIAESAPSIRSGKSRRDSAATLRTSSEIFDIFIGMLGPSMKSLAFTLATVLRDSPFGGPPRFEIHINDHYRQSLTDALALYNTARADALEELYKTIELGRARSEKIKADFEEVAAACGHFSFSLQAFGEEMTKYLDVLDDLKLVRDHNRRSWRWLLFWKAPQLRYPSVLPFDAAVPDRVGDGEGMYDSLINNAASNGNANGNANGTAFGSNTGAVSSSNTNTVPGVRPIRKSQLPRGIPDEMVKRRDTFSWQAAPQSNEMVRRMAQAVLRFFRILMRDDIRFGIKVGIGAMLWASMAFISQTRDMYMHWRGEWGLLSFMIVCSMTVGASNTTGLARFLATLAGSTCAVINWNISQGYALPLMILGWIVAFSSFFVMIDRGKAPLGRTTLLAYNVISLYAYSLSQRVDDDDDDEGGIHPFIMEIAKHRFLAVTAGILWGLIVCRVVWPISARRRFKEGVSVLYLQMGLIWKRGPLAILLRSDCTRSYLKSGEQAALQRYAGRLETLRQGAASEFELRGPFPFAACGRMMAATNRALDGFYAMSLLTQRRGQLTEGERALLYYTATERAMLCDRICHVFQVLASSFMLEYPLTDALPGVTIVRDRLLAKIFQFRKEHATAVKQQFNSNLISTSAIAEEDEDGNEEEDIAQHGSRRSSGISGAAAAAASGTTGGAPPLPPDAAIVNVEERDYALLYAYALVTGQVAEELRIIEKEIEGLFGVLDEEATLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPD9</accession>
    <name>A0ABR3ZPD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046503004" description="ABM domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ABM" evidence="3">
        <location>
            <begin position="15"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="244" mass="26576" checksum="9CFAB1FAE395A983" modified="2025-10-08" version="1">MLGSMILVALLPTLNATYRDKLLETMTNVSHNAFANEPGVHQFALLTPRYNESDNTSLYSIERYTDNAAFQSHLNTSIVTDMFTWINASNIYQAPPTVYQLGPLSSTTENASSTSPSPYEFVHPEVAKAEDPFVVVRQVDYAGGAKAANASLPYWKEVVARARGDSEQSGDDEKDKPGSASTGTLAYGVFGSSDQAGRIFVLAVYVDETAFRQNTAAEGIEEGIEVSQPRFLKLRGGFLYKPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPR8</accession>
    <name>A0ABR3ZPR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribophorin II C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001131</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047522850" description="Ribophorin II C-terminal domain-containing protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="9">
        <location>
            <begin position="181"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="289" mass="30342" checksum="5958B42941F5D5E5" modified="2025-10-08" version="1">MRFAVSSLLLVAAGVAKAASAWSFDDGSITITSKGPSSNKVTEKLNAKSSLGKALVLGSNDVAKITLTTKDNGKEKRPHQAFLLLQDPMSGLEAPFPLTIKESGKGSVQISHKDIPVQLLASGNKVRASLVIGSFGSAQGYVSPSSDGLFDLQFAHDPNMPAPSAATPERYTKKGEINHIFRADPRSPPKVISLFFVLAVAATVPVLFGAWLLLGANLGHLSKALAAAPLSHAAFFGSILAMEGVFFLYYTAWNLFQMLPVAGVVGAVAVLSGTKALGEVQARRLAGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPS7</accession>
    <name>A0ABR3ZPS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF131">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="66"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="325"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="51432" checksum="096275380B07621B" modified="2025-10-08" version="1">MMMERQGSGLATAMAAALRRRDALYTANLTPAEIAQLDLSNKHSLEALVTVVSAVAMALITSTVVLRLTVRRYSVGRFFLDDYLVILASLFTLVVCAVVIAATKFGLGQHVWNLDFSTILDQLKVCIQLMFVANIFYAAAIAFTKLSIIASYLHIFAPRGLLKTTLYVTGGVTIGLGLASVPATIFECIPVAGAWSLSDDAHCYTFVNFLYASTAINVTTDLILCIVPIPLFWRLQLPQRQKIMISVLFFLGGFACIASIIRLAYLHLLYDPIDVTYDLVSSVMWTIAECTIGIVCVSLPPLRSLFAKFWPGVFGNVNNAHSSNGAGGGGLGAKSNMSPHHPYARQPSGTMNTIGSNRRSVKGSKSAADVGVIAMSSMPSHHSRHSRHSLHSSEFDDDEEDTSSHGRLAKKLDEGSPSTVAGSTAGDEVGLTPPEPEVVVSEKPQRRPATNDVEMGIVHSPDSSRPDSAWNVRHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPV0</accession>
    <name>A0ABR3ZPV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001166</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="12718" checksum="C642508C0B6087FD" modified="2025-10-08" version="1">MSTSSVAPPEVTPPPVAAPPHPAAINYVLGFLLVGIAWGFTTPFIRRAAKDHNPPPHPLLERADVKASAVKRRLYGAVFAVVDLLRNPRYAVPLLLNLTGSVWFFLLIGQAGTVKAEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ24</accession>
    <name>A0ABR3ZQ24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Family c-likeg-protein-coupled receptor protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021460">
        <property type="entry name" value="DUF3112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11309">
        <property type="entry name" value="DUF3112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="39724" checksum="4C4D440CDBB44326" modified="2025-10-08" version="1">MSSAPVSGPPYAPTSAGLGGQPVPKVDDPISAVLLLFFIAGAATNMTILQVNMRRGHKFIISGMTFGFCMARMTALIMRIVWASRPHNVSIAIAANVLTVAGVVLLFLINLIFAQRVVRAHRPRLGWSRPVTYLFRALFFSVPFVLVMVIPVSIDMFYTLDTSTRLVLRKVQLVATVWMAILSFLPIPITLLTLFAPPRPPHHGTVENFGQGQMRTKIGLLLFTSTLLALGASFRAGVNFMPRPITAPAWFDSKPAYYVFNYVIEIIVVYTYTISRFDRRFHVPNGSSAPGHYAAGGAVANKSTSTTAGDAADAAERGETSEVDNADSAVLGRKPSLADRINNESDVFGSDEEPTLNNEGKPEQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQQ1</accession>
    <name>A0ABR3ZQQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="138" mass="14920" checksum="610191AEF4A560CB" modified="2025-10-08" version="1">MALATGKAAAGQWKQQVPGNGYRQWVQDWDQRPRYGGGSDPADKEGIVAAAYATTSRLVQSGHVINIAMPSMEDGVRMKAMLDIQWACIRIASMSAAAGDPEFLKDPFDDDWGSDVGEYAEEASQLSQGEEEAGVHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQS8</accession>
    <name>A0ABR3ZQS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PBSP domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007541">
        <property type="entry name" value="Uncharacterised_BSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321:SF12">
        <property type="entry name" value="PLANT BASIC SECRETORY PROTEIN (BSP) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04450">
        <property type="entry name" value="BSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33681" checksum="BBF36C8C9CD5D7FC" modified="2025-10-08" version="1">MTVKRILVNRPKSEIDDTATMTADSGNARPVASSTAVPPVPTPMPPPDQPEGASGPADAEFSDHVSEPPPYPKPKLRIEIRDLNHEGADVFLGAVNVSAVIQQAVGNVQRFLYGRNAWYADPETHITPTRSVTVILRDMDGVAYTTGSELDGDHKEIHFSLRYIAGIKPRKERATSEIAGVLTHELVHCYQWDGRGTCPGGLVEGIADWVRLKCALSPPHWKREPAAVGRWDGGYQHTAYFLDYLERRFGDGTVRRINEKLRLEHYDGAAFWPGLLGHKVEELWEDYADAVKHDRPEASGTVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRJ2</accession>
    <name>A0ABR3ZRJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001143</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="58"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="396" mass="44441" checksum="E73288D13770E463" modified="2025-10-08" version="1">MSSHARRGEMIKGSWSEAEDNELRALVAVHETNWSTISMMMTGRTAKQCRERWVQNLRPGITHGPFSPAECRFIIAYVEKHGQKWAEISRMLEDSGVGKRSDNAVKNWYNGTRNRQRRTAARQQRQSSAARSRAPPAPLNLSQPQRELPPSMSGQHTPTTPVYSEYGYGSHSQQHQEQQQYYSAPPQRYTAYEEPSPSTASSSSRQLPPLHDAIARDHRAQESLLQQQQQCYAQNSYHQQQQPTSSYSYSQTQPPRYADRRSSVYTTMGSPRSDIAYAPSLISDAGSPPSARESPMNAPVSPSTAIPSMMSTLPHPSEKELAALNLQSLRSSSSMDRSWSNRSDEHYVYQPQPQSQPLPFRRLPPPTPMEPAVMASRPTSRPSSRGGAMDLNNLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRT3</accession>
    <name>A0ABR3ZRT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF227">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="66513" checksum="C504BF55EA6726BF" modified="2025-10-08" version="1">MSLPHRPVQLVSLVAAYGVTAWSRRARASSLASAGTDASASASGPSVLSSAYLFVWAFLGAYLIQAIVFGIWSIFLYPFYFSPLRNLPQPKTGNTFLLGQFLRINREATGKPALDWVNSIPNDGVIRYLGLFNQERLLITKPKALAEVLVSKNYDFTKPAIVHQALSRILGVGILLAEGDEHRFQRKMLAPAFAFRHIKDLYPVFWQKGRESVVAMRRQIEAQRAAAPANAPAEDATRIEINGWASRVTLDIIGTAGLGRDFRAIDDPNNKLTSTYRAMLNPTGAARVLAILGLILPRWLVTSLPFRRNTDIVDASRFLRQTCSDLVQEKKAKMQAGKRAEADTNTPRVTDVDILSVALESGGFPDDKLADQLMTFLAAGHETTSAAMTWAIYLLCANPEVQDRLRAEIRANLPALGDDLELDPGLKDVADAVPRRDIASTDLDHLPYLNAVCSEVLRYFAPVPATVREAVVDTSIQGQFVPKGTRVLLVPWAVNKSEELWGPDALKFDPERWLRTDTSGSGHGAGNGGASNYAFLTFLHGPRSCIGLQFARAEFACLLATWIGRFQFRLQNLGDLDEDSLEIQGNVSARPKKGMHVFATPLDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS54</accession>
    <name>A0ABR3ZS54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000837</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="216"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="317" mass="35357" checksum="FD909EF4738A5647" modified="2025-10-08" version="1">MAYNQYQGQQAQNPYEQYQGNPYQDAGAAENAYGGQEQHEMQPYGQAEPAAGAPVMSQQEYLTQVSNVRGEIRSLTTSVQSIAGLHQRALGGNDPSAAQQLEQLVAQTQLKNTQIRNQLRLLQRDCERTSDSTHALKKRQFETLNNDFKRELQGYMTEEKQYRERYREQISRQYRIVNPDATEEEVNKAADADWGSEGIFQTALRTNRSGQASAVLGAVRARHNELQRIEQSIVELNGLFNDLDTLVVQQDPIFDQVNEQTQSAVGNLEGANKQVASATESARRRRKLKWACFGVVVLIIIAIALGVGLGVGVAKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSB0</accession>
    <name>A0ABR3ZSB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA export factor gle2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GLE2</name>
        <name evidence="5" type="ORF">Sste5346_000897</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="39882" checksum="0E997A6C81D0E486" modified="2025-10-08" version="1">MSLFGTSAAAQPNNTVGDLKGDVAVPNPPEDSISDLSFNPSPNDQKDFMAVSSWDKKVRIYEVNTSTGASEGRLMYEHNAPVFSCHFAKDGKRVVSAGADNQARLCDLESGKNETVAQHDQPIRSVKFFEIDGGQQMIVTGSWDKTVKYWDLRQQQPVAAVQCQERVYTMDVKDNLLVVGTADRYINVINLKEPTKLYKTLQSPLKWQTRVVSCFNDSAGFAIGSIEGRCAIQYVEDKDSSSNFSFRCHRDQAQGNTTQVYAVNDISFNPAHGTFSTAGSDGTFHFWDKDAKHRLKGYPSVGGSITSAKFNRDGKVFVYAVSYDWAKGYQGNNAQYPTKIMLHPVLPDECKPRPSVKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSF4</accession>
    <name>A0ABR3ZSF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33859" checksum="977A779F5EC4C834" modified="2025-10-08" version="1">MAITKSNDRVPRGDVVASLNFFNPPADGAVPFNYVDTPPAGEPQRNFSDATHDIVIEDIRGRESEFADSPESLDKNAFLLVQNLPPSAETDFVDDESIRKKYYPELEELLLKNVPGSTRVVFFDHTIRRAKKVETVTGTGTGPARGPVLRVHIDQTAKAAADRVHRHLPADEAEKLLQGRFRIINVWRPLNKGPVESSPLAFASSASVRDEDVVTVEHRYPKERNFIGQTAGIQYHPDQKWHYLSGMTGDERLLLECFDSEALKPGQTKVKGGRLAHTAFNDPRSVPDAEPRESIEVRTLVFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSJ5</accession>
    <name>A0ABR3ZSJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1903646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="94" mass="9862" checksum="A9C2B68488469B79" modified="2025-10-08" version="1">MHIWLVAKFGSRGPLVHTSPDSGLNTASEAVGDYAGSRFAAVNSTPTRQPVPKRSKAQQAAAAIKLEAETEAKEDAEEALVAVKNEGGEEDEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH52</accession>
    <name>A0ABR3YH52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ethionine resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERC1_2</name>
        <name evidence="7" type="ORF">Sste5346_010377</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000138">
        <property type="protein sequence ID" value="KAL1887182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="501" mass="53250" checksum="C7F5B389B4969775" modified="2025-10-08" version="1">MSAPGYDGLTIATVSGATDAPGAMERTRLLSGRQDHGYLTTDVGPVKVDPSAKSEARLVAEEARTLAVSSVPVIASYMLQNSFQTVSIVIVGWGYPEGLSVAAFAYMFSTCTGWLIGMGGTTALDTLASAAYMGSDKAYTGILLQRAVLVLTLFYLPVAVVWIFSDRLFLALGQDATVARDACRFLTHLIPGALGYIYFEIVKKYLQAQGILNAGTYVLLITSPLSALLNYLFIHKAGMGVMGAPIATGIGYWLSLAGLVLYAKYVQGSACWAGWDRRCLQNLGVFARIAFLGFIHLGTEFWAFEIVALVAGRLGNLSLASQSILMTADQVLVTIPFGIGVATSVRVGNALGLRDKTAAQRSANTALLLSVCVAACLMAMLFATRYKLAGLLTPDAEVIRYTADVIPLVAVFQIFDGLNGSSGGALRGLGKQHIGAAANLGSYYVVALPLGSWLAFAGWELSGLWAGQLVGMFLAATIEVRSLLRVDWDTEIELAFERISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHS5</accession>
    <name>A0ABR3YHS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010123</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="144"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="523" mass="58558" checksum="6F20BEEFCC55526C" modified="2025-10-08" version="1">MASQSQSQQRSRSEERPMSQTDADHADSVQQTRTPSRLTSYFPLGYRDAVHQWWSSVSSSAAERGVLAYVPFVREAKAGSQPDLSMTTQQQQAGGAALSAINSANAEDPYGTRLWRSQMVPLSGKNRALNEYSIERVGEENEETLVMLHGYGAGLGFFYRNFEPLSRRQGWKLYALDMLGMGNSSRPPFKVRAKDPQAKITEAESWFIDSLEEWRKIRKIERFTLMGHSMGGYLAVSYALKYPGRINKLILASPVGVPEDPYAVNAAMPEPEESTLVNEFTQDQNTVAEGATNSTSANHNHLHIKKKAAAPAAKPERRPLPGWLVWLWDANVSPFSLVRASGPLGPRLVSGWTSRRFSHLEQDEADALHSYTYNLFRQRGSGEYALPYLLAPGAYARSPVINRIQNVGRQVVKPAQPATATTPATPEVKETGFPIVMMYGDHDWMDVAGGYAAEEKIKKRIEQALLTSTPEEQRRENGSAKVLIVRNAGHHLYLDNPDEFNKYIDDELAETQKSEKRRRQQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI31</accession>
    <name>A0ABR3YI31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arylsulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF9">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045988417" description="Arylsulfotransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="61626" checksum="7EB36A678006ECB8" modified="2025-10-08" version="1">MRHTLSILGFLALATTVLADTTYRSRPDLSPPHLNITIPCDARCASGYLFVSPFTTYGEPDDRVSYQVAPYILDSTGDLVWSGFGYFAGWTGNLQAARYQGKDVLFSFEGLHNGNHGHGHGHHTLLDDHYNVVKVLRAGGHRVSDKHEFEIIDEKTALFQIYEPTQRDLTAWGGDDEQTWIVDARFQELDIATGKVVFEWSSLDHVSPNESALPLPRGLAGIGRSSATAWDYFHINSIIKGSDGHYLLSARHASTIFKINGTDGSVIWRLGGNRSDFTLGDGVRFGFQHHARYFNEDPQGSGEVISLFDNSVYGSESAGNGNEIRINPYSRGKYIKLDHVAKTASLVRAIEPPSVAVPDLSKGDPPILTKSQGSLQSLPNGGDFVNWGSEGQITECDADGTPIFHAFFGKDFLRDKLQNYRAFRYNWTGYSPEDPAVFAESSSEGSVRLFVSWNGDTVTTSWRFSWAEETDSITTDGKTVTTTVWKNKTVARRGFETSTRIYQPKEVRIVSVKAEALGAGDSVLGVSSSVVVQKALTKMVETVGNDRLVGQETLGFGIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJR1</accession>
    <name>A0ABR3YJR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromosome segregation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051190">
        <property type="entry name" value="Baculoviral_IAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771:SF5">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="260"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="574"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="684"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="710"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="763"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="868" mass="94329" checksum="C7C0B4FE72E98E47" modified="2025-10-08" version="1">MDATDYDEQYFIFDNRLSSFQGPQPISKRRPSTAAGSRAPKALTWPHKSPAPIDLARAGFFFNPQPSNPDNVRCFLCHKDLDGWEEDDDPLQEHLKHSGSCGWAICAAIELELGDVVNEDPRLPYLLDARKSTFAGRWPYESKKGWKCKTKQLAEAGWKYTPTLESDDNTTCTYCQLALDGWEAGDKPMDEHQRRSPNCPFFTLTSMNPAPKKTTGRGKTARTSKATRLSVQSVATVTSDAQSVADPDDSILTTATVVTQGGRKTAASRTRKTATGTTTAKGRKTRTKKDEPVPVPEPAVEEAAAVEKDTTIAEPQPPAPTKASRGKKRTSEEIEPATATEAVEAPAPKKKRATRVRASNNSVQAENNDYAMFDPTPRNADESAIEAELRALEKDMDVDVDMDQQLQQQLEKDQQQEIQVPKKGRKTGTRKVSKQTRKAKEAPVVPEPEPEIEAVEPEPIPEPEPEVQEPVEEPEPEPVVVPEAKPKTKARTKSKKLSLPPRQPSQPRLSLDDIEQMEGPDELHEESFMSVGSTNTVVHEAIEEPEPELEDEPECEPTPPAAPPAKKRGRPSKKSIASARSSASIRSSAAEQAIEAQLQATVPTKITPIPPPSIPAMAMPIEVSAPKKRKSSNVSNTGAAAAPAPTATRKSQTDKDKALPPLPTSKRVKEEARPALTPIPIPVPVAAAVSKPAPATPHKNRSPVALAKQATISPSQSPQSSDAENQPPSSRPATTSAKGKRIALAPMQIPPPTVATPDGISTPVRTDSPSKRNNTLGGLRSAVSWSAVDVDTIFGINKENGEDILESLLRKGTDLNTPEKTMTVEEFIFHNAGQAERLLKEDCEAMVSIFEQQGSRAMRVLESLEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKR0</accession>
    <name>A0ABR3YKR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C-5 sterol desaturase</fullName>
            <ecNumber evidence="7">1.14.19.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERG3</name>
        <name evidence="7" type="ORF">Sste5346_009816</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.20" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050046">
        <property type="term" value="F:delta7-sterol 5(6)-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="169"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="348" mass="41430" checksum="331F835BFE153C8E" modified="2025-10-08" version="1">MDIALELMDTFVFDYCYSAIFPPAAAAYKAGYGTNGTAPQTFSTWQYEPSSFLFTLEPSRYAYETSVPRDNIFRQYFSLFLITWFFGLLTYFMFSTLSYVFIFDKKTMEHPKYLKNQVWLEMYQANVAMPIMALLTAPFFLAEVLGYCKMYERTSEGPGRWYDIAQIPLFLFFTDMFVYFIHRGLHHPRIYKHLHKPHHKWIMPTPYASYAFHPVDGWMQSLPYHFFPLFFPLQKWAYLFLFIFINFWTIMIHDGEYVSNNPVINGAACHSIHHLAFNYNYGQYFTLWDRLGGSYREPEQELFDKKTKMSKDTWKKQVKEMEIIVKDVEGDDDRVYDPVDPAETKKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL02</accession>
    <name>A0ABR3YL02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Six-bladed beta-propeller, TolB-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF1">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163622" description="Six-bladed beta-propeller, TolB-like protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="32356" checksum="6FF1B1FF40827174" modified="2025-10-08" version="1">MRLLSSLAVTAALFLPSYAAPFLKARQATAASIYKLPGSAWIENLVVRPNGQLLLARLDVPELWSYDPATKAGAKVAGFTDALSLTGITEVSPDVYAVVTGNFSTRGFSVKAGSWAVWAVDLTGTTPKTTQVKLVPESGFFIGIAPLDKNNVLIADAAKASLYTMNLDTSAYSVVLTDASMKAPAQGSLVEGVHGLKYQNGTAYFTNTFGGGFYKVPVTLDSATGKVTAGKPTEIAALTMAEDFILAPDGSGSYYVAQPNANSITKISADGKSSKAATATSCSSVAFGRGANDKNMLYIATTNGAVFSASIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLF1</accession>
    <name>A0ABR3YLF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF26">
        <property type="entry name" value="L-SACCHAROPINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="48671" checksum="44348D7A416AD015" modified="2025-10-08" version="1">MTDKSARVAVLGAGCWGLSTAYHLQKDGYTNITVFDRASELPSNQSAANDLNKIVRAQYSDDFYTDLGLEAIAAWKTEDWAPYFHQTGHLVMLSGYASEKAQGIFGGAANYISNHRTMKGNATLGLDTPEKMREFCWQLTGPLTNFKSYYNRAEGYAHSARAVGGIAEKLKERGVKFVLGPEAGLVEKLFFEGEGEARRCTGFTTHDGTTHNADLVVCALGAYGAQLVPQVGLFSVARCWSVAHIKLTQDECDVLRGIPVVNSMDLGFFFEPDPATRLLKLTPLGAGYSNYGSTQTSLPPLASGDTAQNTALAGYVPQADEVQMRRLLQETLPYLADRPFVEKKMCWFSDTADSEYCIDFVPNTSKSLVVLSGDSGHGFKMMPIFGSWVKTLLEDGQQKLPRWTWRNVDPAQGGADWGGDVSWRFGEAAETSAIVEERQKAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMC1</accession>
    <name>A0ABR3YMC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Long-chain base-1-phosphate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LCB3</name>
        <name evidence="11" type="ORF">Sste5346_009224</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03388">
        <property type="entry name" value="PAP2_SPPase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="584"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="10">
        <location>
            <begin position="123"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="463"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="609" mass="67144" checksum="32AC0D886D78AAF4" modified="2025-10-08" version="1">MGGATASYNGAGRGGAAADIPTIKVGQESGHEGHGHSDKDVVDAGLRSLDHYKRALPKWRYRLRQRLLPLVRWETPYLAYFQNKMRSPALDSYFAITANLGTHTFFMIGLPMLFWFDYQKFGKGLVHILASGVFFSGFIKDMCSLPRPLSPPLHRITMSDSVALEYGFPSTHSTNAVSVAVYAVLMLSGSDFAPSTKFFLECLSYFYAFSIIVGRLYCGMHGFFDVIFGSALGAVISWIEFYWAPALDTYMLQSSWWAPITAALVIIVLVRIHPEPADDCPCFDDSVAFAGVMIGLEIGTWHIGRLRDAFSLLPGGIASPSWPIALARVVFGVLIVFAWREVMKPTLLKVLPFLFRIIETHGLNLPRRFFVQASEYGKIPEVLMLRTDNVIPSVSDIPIMVRNIRNARRGRSISIGPQSAADAYETLAYRERRRRESIGSQGSVRSKSSFYDLRGEQAEAANASAVSVGNGEATQPTSATTTGATSGFSVSNAANDRESKGRSASVVRKNSLAQFEEMMGQGTVVEAPPQHGTTAFPRLNTEDDPSIDEPDLFVGRQDELGEREMFEKLVKPRVRYDVEVVTKLIVYTGIGWLAVEIIPVVFELIGLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMN7</accession>
    <name>A0ABR3YMN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02208">
        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-1" evidence="1">
        <location>
            <begin position="101"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="219" mass="23500" checksum="03AAA62861129AA6" modified="2025-10-08" version="1">MSATIFPTASRVSCTVGRSIVARAGSCNIVSLSPRLYQCSQPFSTHRPLRSSGIDPSLPFVTRLQEVPTYGPANHTGTVNRRLIDPVTVGSHAIELLHGTLSATGADKARAAPHYHPNMDQVCYLLSGRALCRTLVPGKPGESLAGTDIWREQIIEKGDACFFARGVVHEVIALGGDEVLEAGKGNKDGEGNVQVLVMYSPPYMEDPVNKTVVWTGKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN76</accession>
    <name>A0ABR3YN76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TIM8</name>
        <name evidence="10" type="ORF">Sste5346_008651</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="93" mass="10631" checksum="BB5A9C75F2D4DE86" modified="2025-10-08" version="1">MSTSSLDASAINNLSDKEKEELRQFVNTQTQRTRVQAQTHNLTELCWKKCVTSPVKSNTLEKTEEACMSNCVERFLDLNILTAKLLSNMQQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN82</accession>
    <name>A0ABR3YN82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Thiamine biosynthetic bifunctional enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">THI6</name>
        <name evidence="16" type="ORF">Sste5346_008683</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="15">
        <location>
            <begin position="9"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="570" mass="58579" checksum="01EBD54958582779" modified="2025-10-08" version="1">MPPKVDYSVYLVTDPTLAILGPGRTVVEVVAAAFGNKTTPSSSNELPHVGIVQLRDKDADARTMLATLAELHSYTGPAGSPLLVNDRVDVAVAAMSRGHCEGVHLGQDDIDVATARKMLGPDAIIGVTASTVDEAVTACRDGADYLGLGTVFATPTKTNTKHVVGTAGIQRMLQAMTAAGFGHVPTVCIGGVNASNARRVVFQSGFDGRDGQAAKALDGVAVVSAIMGVADPGEAAATLAEQVRLGKTQGPTGFYRALTTPFESYSTLSTPPTSSAIQRILQALHETTPLSHNMTNLVVQNIAANVALAVGASPIMSNSGTEAADLARLPGSALVINMGTSTPESLANYVKAIGAYNAAGRPVVFDPVGAGATAVRRAAVRTILAAGYLDVIKGNEGEIQTVYLSGLSEEEVAAEPAGLAQQRGVDGSNSLDTEARIRLVRRLAAREKCVVVLTGAVDYVSDSRGARVVAVEDGHPMLGQVTGTGCSLGTTISATVAAAATLRDSSDSEGIDTFTAVLAGMVLYERAAVRAATLPSVKGPGTFVPAFLDELSACRRAAAAGDMQWLESQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNL9</accession>
    <name>A0ABR3YNL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP-binding protein rbg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RBG1</name>
        <name evidence="5" type="ORF">Sste5346_008676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="64"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="290"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="367" mass="40506" checksum="3E64D2E16AAB1D54" modified="2025-10-08" version="1">MSTTVEKIKMVEDEMARTQKNKATSYHLGQLKAKLAKLKRELLMPSSGGGGGGAGFDVARTGVASIGFIGFPSVGKSTLMSRLTGQHSEAAAYEFTTLTSVPGQVTYNGAPLQMIDLPGIIEGAKDGRGRGRQVIAVAKTCHLIFIVLDVNKPLTDKRVIEQELEGFGIRINKQPPNITFKKKDKGGLNITNTVPLTHIDNDEIRAVMSEYRINSADITIRCDATVDDLIDVLEARSRSYIPVIYVLNKIDAITIEELDLLYRIPNAVPISSEHGWNVDELMEAMWEKLSLVRVYTKPKGKLPDYSAPVVLRASKCTIEDFCNAIHRSILEQFKTAVVYGKSVKHQPQRVGLSHELCDEDIVTIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP78</accession>
    <name>A0ABR3YP78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T1</fullName>
            <ecNumber evidence="2">4.6.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008464</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[RNA] containing guanosine + H2O = an [RNA fragment]-3'-guanosine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment].</text>
            <dbReference type="EC" id="4.6.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.24" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00606">
        <property type="entry name" value="fungal_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104:SF1">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047404602" description="ribonuclease T1" evidence="9">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="133" mass="14146" checksum="D4F146A54E1930D5" modified="2025-10-08" version="1">MLSASVLLLGVSAFAGVATATPVAARDTCVYTCGSVCYWQSDIDAALAKGYSLYQSGSTLGSDKYPHQYNDYEGFSFPTSAPWYEFPILSSFQVYSGGSPGADRVIFDSKGKFDSLITHTGASGDDFVACKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPK0</accession>
    <name>A0ABR3YPK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045758924" evidence="1">
        <location>
            <begin position="18"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="284" mass="26911" checksum="6E826CBA4B9B92B9" modified="2025-10-08" version="1">MKATQFVVLLCAGIASAAKCKPALPSSTSSVASSVSASASASASASASASASASAVPSSSSASVSKSASSFGSSSSVAASASASASSVSSVSVSASVSASASLSSASSASAASSVASSASSVAASSSASAPATSATCGPASPNLLGANANFATNSDNWVLNINAGSGTLESTSCEATTNQCLEFVTTANNNPVVGTYLTTVAGSSYTVTFDFSFISGTAASDSIVCTVGGSSTVSKTLDLTATGFNAITLDFTAATTSTSFFCSGTTVGAADIAFNDFSQVLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ7</accession>
    <name>A0ABR3YPQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF48">
        <property type="entry name" value="ECTOINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30350" checksum="54F25251A021A1EB" modified="2025-10-08" version="1">MAVTADQVAFFEKNGYVIVRDFLTPDQVTDLQRWAQEVHDWKPTPTSEFMPYEEVNAKGETVLCRTENFADCHKGFDELLRGAKLNDLLQGLSGEPMHLFKEKINYKLAGSGGFAPHIDAVAYTHIKRVKHLTILLSVDPSNLKNGGLEVVDGSHKMDVPLNPTTNCIESSWVDSQRWTPVELEAGQLLVFTSYVAHRSGANTSTSDRKAIYATYNRACEGDLRKGYYEHRNKEWPATHMRKEGESYAAGALTYGFGSPMLSVDQGKQVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR95</accession>
    <name>A0ABR3YR95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF6">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="56832" checksum="47CEC0377EF76CD2" modified="2025-10-08" version="1">MAFSFVNYEGPTLPKDPGVRKTIRRQAMRDVAVDRRTRGRYGQANRLENLRQYPVFVHGFVDIDDQTKMSKDKTKSKDASSRPGRLRLGIGMLSSVKSDLVRVRAGEPLSISASALGNPKLAHFIISRYGDLPALRYATDCIVNKLRQVLMRSRGCGSPLPHYEKEPLLLYNQALRAVQAALEDDTLRLTEETLCATELLAMLELLDENIPSWMHHASGAAQLIQFRGAHRFNTESGMTLFMANIGTTVMDAILGNKACFLEEAAWKELMRTVIRNDASLVHLRDISLDIWNQIVTGPRKFKAVTDAIASPTPLDRVALDTIIQHLMEDRASLLGWMERAKQIPGLRDGDFEVDEYGIIFPRPSFERDDSSPDRVTFLALWGTNIMCRILKTRLLVAMAPAWFRTLELECQYLAAKIVSLDQITTANNSSRKGVLQTSFISQSTWIVKGVIETKDIWAEGQDSDGGENMIETWKFEAWCRAIGRKFPSTPHQGINSLCNASQPLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRA9</accession>
    <name>A0ABR3YRA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038769">
        <property type="entry name" value="MTC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38426">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38426:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1536"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1339"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="944"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1176"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1380"/>
            <end position="1393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1583" mass="170043" checksum="8D42ADAED345AE3C" modified="2025-10-08" version="1">MADSLREAASSLQPPATQSSSLTTGDDVLDGSQRSSTSRDRPSQGSSTAGSFLTLSPSASSSHDVPPEPASTATSTHLQLNTQASPDGPSPPQLPQRFGQSPNNAYLSNASSSLSRQNYDLSPSASNSNSISPPTPPANTSNARASRTASHRTSHRHNRSSGAFLLSDSLGSAGHASSSHGKSTHARSSQRESTSGSHKNRSNVGRAAGSRLSAAPETPEKGAALSSPAGNNTPDSTHSSGSSRRSHGSSSASGTARAQTPESGAASPAATAHPAAPALPTGQPLDLDSAQIVNMALNLSESRRLAARRNVSVSQQLPPRLAPLPDSAVGGSLLRQLQQQRRISRTMSPKPDRGGAGGRVSSSGQFPPGQSPRMSTSSALQPPFELLPDGTAAGQGQYRYHFSQSTLARAQKAKDYLELLAQHRRLLELIPPLTPAAAARSRATSIGSPPTTSNNAGQPQSLFLTGTNSNGDLVLGSTRLGRPYNPLQYIRNRKVRVRERRAIDGQAQGFGDVAKATDWVDGVAKWTATGQGRMLGGYTLPAFSTADADTALQSSPPPASRAAGQAVLAKPKRPRIDWVIDPADMIADVYWLEQGDNKKLVEDHHWRRVFPQDSSLYQPISQRVDDSMAGVKAGEQADGIGNIPALAADGDTSTTNSRPLYAMPVGAHLKPVENSPEPDHGSARKRARQKLSELRSFHHRHNSSVHSQDVQRLRRGSFSDTSDSDNDRRRFGRARADSGTANGAEVLNKNMMGKIARENRERDENAAAAASVSASAAAAAATSTTASKEQKRTATLQASSTGVTPLNGKQARPESTKAAKHPVTAAAIDSPSKQGRASLEIPTVGRRLSLDYDSSRPTSPELHPFSKDGLGFVPPLGGDLSPPPSRAQSPPRHRFGKVKSIFRDHSRERDHRDRDRDRDRANNTILDRGEDYIEPSARSSATVQQHQHQAHQAQQQQHQDYVESTSAPLTAVSTVADDLRFASSNEAKGPHSPIRKIGTRPSPGTFDTHRSHTSISSITGHLHSTNTNPNSHHHNHNRSEEGGSSGGTLRGFFKGGPRIDTMLRSGVSKVSDMLWRREGSEPLFGDASAAAAAGAHMSQQSSSDDDSESEAAPRDRFRNSTLPSRSPSVNPGPEVADKSPYSTIKPSEKHYLDVMPTFGRGGGEDPITRPPSRQSARFERLKPPRIDVRDASPSADDAANSLKQLGESSSSNANRRNSSLQPIGRQPHRGSQDSDYSESDTRSRRSSRVSGVASSIAGSLADGTGTLQPLPRKFSSTSAMSGVKGERPRWSLSQPAYNHHHGSLSRRELARLRASMYSSAVLAKELSRRANEPKILVRSWDSAKRNSKAKANDNGNGNGSARRRSSTALDAAVADKGADADDDNDHQNDDDAEVAVPNASDSGPIIVRGSNGEQSLTWADIAAYGPNPTELARRPVKQVEIYPLAAQVLGSAIQRSGHSWQISAEMFANTTVPQLRQRIEGVRTRVSVELSGLARQAADEADEVTRDLMAVQRLQVKRVEDSIEKMLRRRRRRFRWVRRAGWLTVEWLLVGFMWYVWFVVMLARIILGFGRGIYSGVRWLLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRR9</accession>
    <name>A0ABR3YRR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="39"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="536" mass="56446" checksum="8527A03B46B81EE5" modified="2025-10-08" version="1">MSFKPEVEAVDGAPTPPPIPSTPPTTALPPVSRARRAVIMLSLCLALFLSALDITIVATALPTLARHLNASAAVYAWIGSGYTLANTASIAVWARLSDPDLGGRRPVLIAANTVFLVGSVLAGVAPTAGVLVAGRIVQGLGGGGIGVLVTIVIGDLVSLPTDRAKYYGLTGLVYAVACSVGPVLGGVFTQTIGWRWCFWINLPFCAVSLVVLIFALNLNTPKPTVRPTLLSRFLRLRSLDWIGSVLIVGGTIAFLYGLEAGSATATDNKSSWSSATVIVLLVVGGLLLVAFAVYEHYFPPAHPLLPTRSLFGSLTNIASLLIMVLHSFVFISYDYFLPLYFQVGLGFEPIRSGVTLFALVLPLSAATLASGYAVRKTRNYRVAMWGGATLMTLGTGLLIDLGGPPAHLVKIVLFLVVIGFGAGPLFQAPLVALQSHVVQEDAAAAASASAFLRSLANAVSIVIGTVLLQNGLHGHGITDLITPPTMFADAVRRMWIFYTAVAGLIFVCTLFVKKMPADNAQEEVESQEVANEKESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS21</accession>
    <name>A0ABR3YS21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ubc7</name>
        <name evidence="10" type="ORF">Sste5346_008442</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23796">
        <property type="entry name" value="UBCc_UBE2G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="4"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="166" mass="18530" checksum="E12636F00ADC0FFB" modified="2025-10-08" version="1">MTSTAHRRLLQEYRTLTNGPPEGITAGPVSEDDMLTWEAVIQGPEGTPFEGGVFPAELKFPKDYPLVPPTMRFVGCEVWHPNVYASGLVCISILHPPGDDPNHYEHASERWSPVQSVEKILISVMSMLAEPNDESPANVEAAKMWRERREEYDAKVRANVLSMLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSR3</accession>
    <name>A0ABR3YSR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045202061" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="37"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="287" mass="30854" checksum="8E1450E56A12DF35" modified="2025-10-08" version="1">MYTKSIIAAAAILPGLLVSATQPPSYPGFTMIWNDTFAGAANTPPSDKNWKTITGYLNQNSESEVYSSSTKNLFLTGSNSLQIVPLKDSAGGWTSGRIESVGSWLPTAGQKTRIEGRIRQGDGSTATKQGIWPAFWLLGTAYRAGTKWPECGELDILELRNGVPTAFGTAHCGTYPGGPCNEPNGKGSTINFGETSLAFHTWTITWDLTNKDWSSQSIQWTIDHTVFFTLTGAQLDQTTWRTLTANTFNIILNVAVGGDFPGAANSATQGGTGSLMEVQYVAVYMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI2</accession>
    <name>A0ABR3YTI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106705" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="51"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="130"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="178" mass="18497" checksum="176175843E91EDDF" modified="2025-10-08" version="1">MYLPSAALLLSAVIGAAAIPASAPASTPTTFVVSPSTPTATASASTSHCYLHVTAHAGDSCASIAAVFNIDIATFRRMNPGIDCSHLKGEYCVADGSVASSSSPPAPSRPPSSPSAPTPHQSPITPACRSWHLVARGDTCEHIEQALGISDADFRSWNGFLDEDCTNLWLDYYCCIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUF3</accession>
    <name>A0ABR3YUF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein phosphatase methylesterase 1</fullName>
            <ecNumber evidence="3">3.1.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PPE1</name>
        <name evidence="13" type="ORF">Sste5346_007514</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.89" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="12">
        <location>
            <begin position="574"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="364"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="740"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="399"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="899" mass="95168" checksum="D018A80DF7763D4A" modified="2025-10-08" version="1">MAAQPETRWVGAAGAGGYDLRSDVMTTPTANMLKAIQNCTLLDDVFREDTTTIDLENHCAKLAGKEAGLLVLSGTMGNQVALRTLLKQPPHAVLCDRQSHIFKYEAGGVSSLTGAMLQVVIPKNGIYLTLEDVKANAVTGTDVHDCTTRVISLENTINGVLMPLAEVRRISEWARSHGIKMHCDGARLWEAVASGAGSLSDFAACFDTVTLCFSKGLGAPIGSVLVGSEEDIRHATWIRKSIGGGLRQAGVIAAPARVAVDETFGTGPNGEGGLLRHTHTLAKEISKMWTDRGGKLLYPVDTNMLWVDLEATGTGYNELAEQAEVEGLKIFGNRMVINYQIYQNRETVVPKLERIFTKVLEGKTATPTAEKEATSESAASGQSMTTETELETARPRHTVLPILASPSASSPPKVATASATASAISNPVPPSQQQSQSSSSSLAPTAVTVKAMSELQRRWAKAKMDAMGGNSSNSIGEEEEEVAADGRTSLDSDSASSASSMGTVVPSASQNLFARPQGTARSRGGSTGGSGGRTLEPIPWTAFFERELFLDTGDGRGIVHHAYVTSPTGSGPLFVMHHGAGSSGLSFAVVGSEIRKRLPSAGILSLDARDHGLTKAPGDLGKDLSLATLSSDLLAVIRLAQTQMHWPELPPLILVGHSLGGAVVTDLAFSGRLNTTPTSSSLLGFAVLDVVEGSAMDALQSMQTYLGTRPPGFPTLENGIEWHIRSRTIRNATSARTSVPALLVDSNAEGGKESGGADNGDKDTNSTSISEYSAPPPASPSGGDKAGTKRKPWCWRTDLGATQPFWEGWFVGLSKKFLGARGGKLLLLAGTDRLDTELTIGQMQGKYALQVFPEAGHFIHEDLPEKTALTLVDFYHRNNRGALVLPPKVSELLAQGKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV43</accession>
    <name>A0ABR3YV43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052777">
        <property type="entry name" value="Acetyltransferase_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43305">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43305:SF1">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="175" mass="19299" checksum="EC6DC22DBC4752AC" modified="2025-10-08" version="1">MSPPLASPLFTIDYATSQQDLQDIAELFLEYTSGLGIDLAYQSFAEELAGLPGKYAAPQGVLLIARSTVPEISGKPIGCVALRPLPVPGEEATGRRCELKRLYVRSDARGTGLGEALARRALDETVTRNYKEVVMDTLESMTPARRLYTKLGFAETTAYYETPIKETVFYRKMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV57</accession>
    <name>A0ABR3YV57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Complex I-ESSS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase ESSS subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Sste5346_007207</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Complex I is composed of 45 different subunits. Interacts with BCAP31.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB11 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019329">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ESSS_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637:SF1">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10183">
        <property type="entry name" value="ESSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1892251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="117" mass="12702" checksum="AE5241B58BF9AAF0" modified="2025-10-08" version="1">MSFTASAAKRALASTASATSSTAARRTFASTARRSGGGHGSQYDPPSGWLFGVKPGEKYKNEGWEKPMLWGFCGSLLVFACVIPFKPDTSIQTWALEEARRRLEAEGILQDPFPESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVC5</accession>
    <name>A0ABR3YVC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cellobiose dehydrogenase-like cytochrome domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF5">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE CYTOCHROME DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319955" description="Cellobiose dehydrogenase-like cytochrome domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Cellobiose dehydrogenase-like cytochrome" evidence="3">
        <location>
            <begin position="40"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="460" mass="44257" checksum="5D21C99D561CFE86" modified="2025-10-08" version="1">MGNFNVANLAALALASQATLASAAAIHPRQAPASPKTARYCDNSLGATVCYSEFTAATSGTVFRFAIPEVQKAPFDTLVQVVAPVAVGWAGLAFGGSMAQNPLGLVWVNGDKGVASSRWAVGHTPPTAYTGASYNVLNTVKNATHWTVDAVCHGCSIWGTNSTSLNPNSVNKIGYATSKTAPTTPSSNLSTISIHSEKGVVLHDLSVGKVDSNTFQRYLLYLSSNPSESPGGDGDGSASSANLPVPTLPKNIPTTTIGLPQTQPGQGQPAKTTPIAQTTIDASYAPTTIKGTPARPTGVTVTVTVTSTPRVGGGNPFQPTAVPTPCSRGGFGGFGGFGGGRYCTVPAYGGGGSTGGGGDDGDDGDDDGSSTGYGNGRGGGSGGFGGFGGGGLGGGGLGGGAGGGFGGGGLGGGVGTGSGSGRGGGSGFGGFGGGGFGGGLGGGFGGGAGAGAGGDDDGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVE8</accession>
    <name>A0ABR3YVE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF6">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364976" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="50"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="352" mass="37237" checksum="D7D54F32CF0E3F23" modified="2025-10-08" version="1">MIRSGLLAFASLAYGAPQFGGGSSSSGGSTGHGTSLVRFGCSQVVIERLDPLVNPGMLPSPHVHQVVGGNAFNASMASTDVSGIATCTTCNFPDDLSNYWTANLYFQARNGSYKRVPQIHNRMEDGYTGGTTVYYVSPGSGKTTAFKPGFRMLVGDTTARTKPTTVNMAMQSCFRCYTGPNFKGDNMSPCADPKLDTETLPVGPCLGGIRSNIHFPTCWDGVNLDSPSHKDHVAYPSSGPSSFATTGACPASHPVKIPQVMLEIVWDTTGFNDKSEWPADGSQPFVLSNGDKTGYAQHADYVFGWKGDALQKLMDGGCFGAATCNGVQIQTAEAANKCAVKDTVLEDTNGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVP0</accession>
    <name>A0ABR3YVP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-mannosidase B</fullName>
            <ecNumber evidence="3">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Mannanase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_007382</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="13">
        <location>
            <begin position="14"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="11">
        <location>
            <begin position="203"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="12">
        <location>
            <begin position="702"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1891838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="893" mass="100255" checksum="58922F53E205A50F" modified="2025-10-08" version="1">MSKSTTQIADGWRWRLANTNGNKEAERRSAELKEWTPVTSFPSVIQAELLARNLIVDPYIGENERLVQWAGEADWTYATTFKAPADIEGKTNVDLVFEGLDTFATVRLNGTVILESDNMFVPARVPVKSLLKSDGENDLHITFRSAITVGNELEAKYGARTSLMRDKRRMHMRKAQYHWGWDWGPVLLTAGPYLPVSLEAYDARIEHVHIVPSLAEDHSSASVAVEVAVVQAKGDSSLLVEVEMVDAAGTSVGMATVPVSGNGTAVATASVSISSPKLWWPNGQGEQHLYTAKARLVSSSESVIDTVNTKFGVRTIELIQRPLTSAPGTTFMFRVNGRDIYIQGGNWIPADMVLPAITRERYFDWVRLAREGHLNMIRVWGGGIYETDDFLDACDELGLLVWHDYALACGDYPVHDEFVASVAAEVEVQTKRLRNRACLALLCGGNEDFMFADLLTKIDYDRKDLTGPFDDKPFPQRKFYLETIPRLAEKLCPNIPYWANSPFGGEDSNDLTVGDIHQWNVWHGQSLPYQDYKKLGGRFVSEFGMHGFPVDRTVAHFCKGAPPHQWHAQSQLIDCHNKSEGAHTRISRYLAENFRYDMTNLANFSYASQLMQSEAYVYALQHWKRQFRGPGREECAGLIIWQLNDVYPCTSWAFVDYFLRPKPAYYSIKRAFAPLAVGVERSVSSLWIDENKLDEPKGPPSFQLWAHNTSPKAVEDVALKLQAYNLATESWLPLAEKDSPRPVEIVAGYTTELGELAPPADWTPSTLVVLEATLVDTTTNAVLARYVDWPEPYRYLTWKADTELTIDVAHEKHNGYESRVTISSNRALKGVWLEPIYDGTEADDSREPNWEDNMIDLMPGQAITIGVNGLNSRGVKGRFLADWEIGKENPTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVQ9</accession>
    <name>A0ABR3YVQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055560">
        <property type="entry name" value="DUF7136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23584">
        <property type="entry name" value="DUF7136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286653" description="DUF7136 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7136" evidence="2">
        <location>
            <begin position="37"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="34773" checksum="1B761521E8B81D80" modified="2025-10-08" version="1">MRFSPISPSALVAGLASLVGTAQASVDNRTIETVTPAQTVDITLTYPRSEAYNTFERIPIIFSISNPQYAAWLNPRIDYAIGKYGGDYPFEGQCPVYTDTRNMTIDLTKVNLTDPDMPNPLYVYGFFDCLDYQVGEWYFSWTVRTGRAPENATDFVYDNNVTDSGGFVFATVDNGSGRTIVNIEENTSDESCDSVPYAHEFSVSGIAEGSCSGSITDLPGCAVVTNDTGAYIAASIPPPTANLTCGGAINASIADIVKNSPRFMGTCPVLPIAHVDCPPSLTVLDMGTATLPSPTQPGTKSAAVPRMAPGSVSAVIVVIVAVALGGVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW41</accession>
    <name>A0ABR3YW41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="37704" checksum="F791B1505953DED1" modified="2025-10-08" version="1">MSDGKRAVDSDKVWTTLITNLDYLPGLLTLDASLKKVKSAYPLVALFTDSFPEEGKKALAARGIPYQRIAYLLPTKSHRDYSADPRFYDCWSKLTPFGLTQYTRVVQLDSDMLVRHNMDELMDLPLDDPELAAQDPAPPTSRRIFAAGHACVCNPLGKKHYPSDWVPANCAFSLQHADPTKAQTEGADPDPALPNQPMGVELINGGLQVVVPNKVLFERIVSFMDENAADLDFADQSLLSTLFRGRWVSLPYTYNALKTLRWPGVHDPIWQDDSVKNVHYILTPNPWDELDRSAPGQPLKEGLTQDPRNVELHGWWAKTHRERKAAEAAAGIEDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWV2</accession>
    <name>A0ABR3YWV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar membrane pq loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41132" checksum="C80976A644C01E85" modified="2025-10-08" version="1">MVAFRVSAAATLAARSAAVAATALQTRGSQPEPTIQDALSGIFGSVSLTAWICLLLPQLIQNYKSQSAEGLSMAFLFVWLLGDVTNLSGALWTGLAPTAVALACYFCIADAVLITQCLYYNAKTARRDRLLRQDRSRRRSSSTAVAGVNSDDVSEEVFPEEGGEEDEDDSPLLARRRSSSIGLPGSHRRHSTRRSESNLDPLRRIITGEDETPDNNPWLHNTLSLVAVWIVGALGYFASYRMGAWDGSDPVEVGPAPKEDDVYAKIGLALGYFSAVFYLCARIPQIVKNYREKSCEGLALLFFLLSLTGNFTYGASLVAYSQDKKYLLNALPWLLGSLGTIVEDLVIFFQFRLYAPKRNVKPTTGASTNGQASAYGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY58</accession>
    <name>A0ABR3YY58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF30">
        <property type="entry name" value="PHOSPHORYLASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="352" mass="40273" checksum="90D48D7AE3F356F1" modified="2025-10-08" version="1">MQIKDSQLLTGFRDFVGLLDEMWPEAQEYADQALSQLNPRYVHMYTSENDPPYRIDRTVDPRSGSFGTVHKTTNNTDGDAYAVKVFHNVSWNNNRQTILREIGVLELCMHRNIVKLVEAYEVATVPDVLYVVMTPWVPVTLDDLICNPDPLRRKTFPWFAAGMESTLDCAHRLMRELADGLAYLHDLSLKHKDLKPNNILLQHATDAHRITPLITDFGVSKVFRVGGATRYTNSTYEFLSLEQLNHEESSLKSDIWQLGCCYSYMLCVASGGSRAANTLCDSYMCQLRACNIAREAEHFKKALHQLVVYHEQNRPREKRMLHMVADGMLDLNPSTRLDIDMIRDQMASLQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY95</accession>
    <name>A0ABR3YY95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="40769" checksum="4083FC62AEE8F4D9" modified="2025-10-08" version="1">MTVTIVETAMATAIQNGIVNGANGVNGVNGVHDMNGINGLAKGGDSLARDKAAGRNPRFSLPDSTPRSSKTSMVIGGVRIYVYGLDDLPSPAVDASSSTTTEVAVLYLAHNRTRTYRVTEGIAHELLHRYRTDSRPKTMGLVAVTMDMRNHGEREISPAANLTWAAGNERHAMDLLSLIDGGVQDFRLVMDYLPMYLPQFSRLRNVMAGVSLGAHTAWRLAAQAQPGQIAGYAMVVGCPNLTSLLVGRLTDDKVEGTSKDYYDDLDDRQKGRWPRALADLVARQDKQIADAFPADTPILLCNGAQDELVPAKFTAVWAKERGVAPTNDVVRPPYVPGKDSDKPPLIDLLVQENTGHSCTKEMVARIAVWLGDLFASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC1</accession>
    <name>A0ABR3YYC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein YIF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hrf1</name>
        <name evidence="11" type="ORF">Sste5346_006736</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Has a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Golgi apparatus membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the YIF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005578">
        <property type="entry name" value="Yif1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083">
        <property type="entry name" value="YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083:SF0">
        <property type="entry name" value="YIP1D-INTERACTING FACTOR 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03878">
        <property type="entry name" value="YIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="36623" checksum="1A6EFCEFFFDB227E" modified="2025-10-08" version="1">MQRPVYGQSPPLHHPVPQHVSTVPQLRSPPPPTSSQPQPQTYGSPYQQQQPHQQQQQGGGIPMGNMFGQYGQFMNDPTAQVAAQLSHTALRQGQEYVEQNINRYVNVGVLKHYFNVSNSYVLSKLFLVLFPWRHKPWSRKQTVGPAGQEGWYLPPRDDINSPDMYIPVMSVVTYILLSTLVAGLRGQFQPELLGYTASVALAVVGVEILGLKLGCYLLSISNTSQLLDLVAYSGYKFVGVIATIAVAELVNGGKGTGGWIGWSLFLYTFLANSLFLMRSLKYVLLPESSADGRAMQTDTRAKRNQRTQFLFFYSYGVQLLFMWILSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYM3</accession>
    <name>A0ABR3YYM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable glucan endo-1,3-beta-glucosidase eglC</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Endo-1,3-beta-glucanase eglC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Laminarinase eglC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">Sste5346_006612</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF13">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE EGLC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="17" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0964">Secreted</keyword>
    <keyword evidence="11 24" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="24">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286660" description="Probable glucan endo-1,3-beta-glucosidase eglC" evidence="24">
        <location>
            <begin position="20"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="393"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="23">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00025152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00032134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00032906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAL1893180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="471" mass="46179" checksum="1C0C7249705CA674" modified="2025-10-08" version="1">MHSVLSLAAIAAVLPQALAAYQGFNYGSTFTDGSAKAQSDFENDFKTAAGLDGTNGAFTSARLYTMIQGGTTNDVISAIPAAISTKTSLLLGLWASGGDANFANELAALKTAISQYGDSLGPLVAGISVGSEDLYRITPTGIENDSGVGAGPDVLTNYISQVRAAIANTALSGASIGHVDTWTAWVNGSNTAVIDAIDWLGVDAYPYFQNTMPNGIAQGAGLLDDAVSETNSVAQGKPIWITETGWPVSGDQENEAVASTENAKTFWDEAGCPRFGSVNIWWYTLQDSAPTTPNPSFGVIGSTLTTTPLYDLSCSGSTSNTSTTTTAASSSAAQPSTAVLERSSSSAVVVPPPASSSAGGVIVGGGGAGAGSSSAAAPTTTLATTTPVNTVVAPTTTVGSGSGAGNGTSSGSGSGAGNGTSPTTGGSGVTTTGSGSGSSTSGAVVVTNAGVALSGSIGAGFAALMAAILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYT5</accession>
    <name>A0ABR3YYT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="227" mass="25467" checksum="2FE3446C3546348C" modified="2025-10-08" version="1">MDMPVARSWDPALDFLERRSSYRITASTRHTPTRRLTPTTRTLTHKPHSSHSHAHAHPPPHPSSSPPSRMWRGSGEPAKQLACSSCRKKKIKCQPNVDGGRCRACLRSGAECLIPVVDERKLSNSKKLVRELYAKIASLEAELQRRPKASDIRDRDPRRDSFHHIIGVLDDDDRTKTLPEDEPLMLCLPENRINAIHPSASSNAPPMGMLVSTPTLAAIIARDRHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZG9</accession>
    <name>A0ABR3YZG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF3">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="139" mass="14314" checksum="B1C729D11126CD67" modified="2025-10-08" version="1">MAEVHAPEVSHGRGGAGNIVPDDTKYVDGEIVRAGAVGSHDDGPYSTGRGGAANIGDANKRRSLERADRTLIPDAAVRPSGEMTDYHTGRGGAANVHIVPDADKKKASHEGAAATGTSPPPMVGLADKLKHKITGVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZV5</accession>
    <name>A0ABR3YZV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="210" mass="23508" checksum="3F87CBF2613A3ABA" modified="2025-10-08" version="1">MPFTLAIAQTCRIGALYGYSPSAPENNVFCDLLFLLDLVRLTIQCELANGIVYPDQQKQRLSLEFLIHLVGTGVVPIHDGAHEELNYRIDKHIRLLSQRLRAVGHRVQYFGDDLAYLRAVWTEETNFTEGKVHCLFSNEVAVRPDDKNFTPHNIARAYAPLVGVDVDELVDECPDSMENLLLQYFELAKRSGVVAALANMASIAAMGKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY0</accession>
    <name>A0ABR3YZY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006074</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="62"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="504" mass="56363" checksum="AA83BB1840474793" modified="2025-10-08" version="1">MADNEKEVALRGTKVTATAKTAAVSVTGFEDDSATPTEQHSDIPEISAREERAFVWRLDLGLLVVGFLGYTFKYLDQTNISNAYVSGMQTELNLVGNEYNYFTTYFNIGYMVMLYPSCIIVSHFGPHRWLPACEVMWGILTCCLSVAKSYKTVYGLRFLIGLFEGSAWPGYITIISQWYLPEEIALRMSIYNVAQPTGAMLSGALQGALSTNLDGALGRSGWRWAFIINGVCTIAVALAAFVLLPGYPESPNPLSKFYMKPRHIEIALARARRVGRRKQQGITFKSFVRCFSFWQLWLFAIAWPIGGNTTPSNYFNLWLKSLKNADGTTKYSVAMLNYLPIIGQAIQFVAEILFNGFSDFFGVRLPFLLLHATINIISLIILIIRPANESAYMAGWYLNYVGGVSTMLLCSWAATHLQHEPEVRTVLFASGTILAYLLAAFVPLAAYPASQAPNWHIGAKLYLGFAVVSAVLFVTIHFAFRYDRWTEKRQPATKDDSENQEQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZZ9</accession>
    <name>A0ABR3YZZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclohexanone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF12">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="582" mass="65830" checksum="B9BD224C7535DE7C" modified="2025-10-08" version="1">MSDAKPNGVLPNGHNLATPAATPDPGSAVPEYTVLEQNLGDRRPTRIICVGAGASGLNLAHRVDQYMRKTELVIYEKNPEVGGTWFENRYPGCACDIPSHNYQFTWEPNPNWTSFYSRSPEILEYFKMVARKHDLYKYINLSHRVVSADWDEEKAIWNLQIEDLATGEIKSDWGDFMITASGVLNNWRWPDIKGLHSFKGQLVHSANWDDSVDWRGKRVAVLGCGSSGVQIVAAIQPEVANLTTFIRTPTFITAGFAQSKAGPGGANFNFSDEQKKKFREDPEAYLQYRKDIEQELNVRFKFIIKDSQEQAEAFKYSINEMTQKLGADSPLLPYLIPSFAVGCRRPTPGNGYLEALTQDNVHVATDPIEEVVPEGVKLSTGEIIPVDIFICATGFDISFRPRYPIKGLNGITLSEQWKDRAKGYLSLAIPNFPNHFMFLGPSAPVGHGSLLPIAEHATKYMLRMIHKAQTQDIKSVVVTQEAVDDFNIHIDEYMKRTAWSTQCRSWFKNGTLDGPIVALHPGSRLHWFHMLDEPRYEDFVWTRRHGNRFAYLGNGFSTKEAPGKDTTLYFEDTEKDYEFLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1C2</accession>
    <name>A0ABR3Z1C2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="37456" checksum="FC887C91EF83E3A6" modified="2025-10-08" version="1">MTAAGFSSRSLLDQEATIKQFGNDLVEVVKERTAGGKSINLVSFLNWTTFDVLGELAFGQSFNSLKTRQVEGWVGIILGNMKFHAWDVSLWKLPALPHIQYWLTPVKPVEVGFKHAEDSMKKVQRRLADITTKKRDFFSYILPKREGLGITDWGLASYTNALIVASSETSATTLSDERVYSTLKAEIRGAFKTPAAITALTLSTLPYLTACIEEALRIYPPIPIALPRLMPKGGCVIDGYSVPGSTTVGVYAWTVTRDPRRFKDPDTFRPECWIDNTDNDNLEASRPCLAGTRMCMGINMAWIEARLFAVKLVLSFDMEMVDTTLDRNEQECYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K0</accession>
    <name>A0ABR3Z1K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037507">
        <property type="entry name" value="Ribosomal_mL59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="1">
        <location>
            <begin position="18"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="161" mass="18524" checksum="5C975B5A69E63B15" modified="2025-10-08" version="1">MASQSASQYIQLAKTLPPRLLKFFARYPPAAIQATATATPTGYQQDTPNPFKATKHSVTGQWHDPVYSLRRQADLIKMARDHGVMDLLPESVKNPETKLRKRVEFGLRVKGTGVGQSVKGHMHERRMVSKMEIRRKAMLNMPKLIREWKRIGRKNWVRYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2H1</accession>
    <name>A0ABR3Z2H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="254" mass="27564" checksum="CAA82C5F2CB1F55C" modified="2025-10-08" version="1">MSTPADHGHSEACCNVPPIVATGYQLKGEYKTLGGLKTYATGPDDATKGIIYVHDIFGYRDQSLQGADILSVTDKHQQYKVLMPDWFAGEPAPLEIFPPDNQDKMDRLMAFLGKNPPPATAAKLPAYVKAVSETYPTIKSWGVIGFCWGGKVVSLVTSSAENPFAAGAEAHPAMVDPKDAAGIKVPIAMLASKDEPVDDVAAFEKALTVPHHVETFSDQLHGWMAARADLADERIKSEYVRGYKTVVEFFSKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2S6</accession>
    <name>A0ABR3Z2S6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Restriction of telomere capping protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RTC5</name>
        <name evidence="8" type="ORF">Sste5346_005842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RTC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF130">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="7">
        <location>
            <begin position="452"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="393"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="516"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="760" mass="82466" checksum="B789413F56B1A916" modified="2025-10-08" version="1">MGQGQSAPPPVQRSHEELVKELANHFAQKCFTSLELYSLKDNFKSLADATIDSPHVSRDTNNYQPREGKDGDNNEDSSGSGESEALTPHQNNRKHHVLRYLKEDTVARFLAIPDILGVSPVVFQMISYLAAFPFLSEAPAVLGLEQLVIVVTLLTDRYKRVLAHGASDRRTLLFRSLAVHDRKLYSDDKKEAAAAARTPPTGPTGSQGFAIDAPSEDDEEENHNDGGDGDEHDDHDHDHDHEESTLTKDDADELVLAAFDALDYVDNTSVPTGPKASARKASDIAATLHGARIPADNFRRLLMLLILVAPLGPQEQLSLYAGRFTGDALDSLRETAQCILATFLDVETSPGIKFAHFDTIIPVCFPYLFSGFNALFEHFLFSKNLDLSRMRPGAGATNTNSDSSNANTDNNNTTSTSTAPATLTRRKSSAAASIPPKDIPIPPLLLQDSVNNIMNLNILSQLSFFIPGSSLFHRLRPLYSGDNDGFSMGSFETKVFNWRAPTILLVKGTRISDTPRGPEATFANALPPRRFPHGNGKRPDASADDDDEILIFGAYINQPWRLTHRECFGDSETILFQLSPVHDVFGASTINHDYTAFVKPSAANNHAGGIGFGCPSPTGSAVKASLKQHQHVQSAVEGILPLGPLSLMIDANFEFGVMTHDRGHPSSSRGSVAAGAGGAFHPSVARMFSFQDRFSIEALEVWGCGGDDEAKAQAERWAWEAREAESRRRINLGTGDIEADRALLEMAGLIGGGRSGGSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z376</accession>
    <name>A0ABR3Z376_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034772">
        <property type="entry name" value="CPSF6/7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23204">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="43958" checksum="4DBBC03F57C95DE3" modified="2025-10-08" version="1">MTTEEDFEIDIYGDANGDDQSANDNNNNNNNNGQNQGQGQGHDYDDQSHQDDQNNQADQSNAVAKTTEKQSPPTQGVKRKGSSDDRPIDPGATTAIMVSELSWWVTDDEIRGWIAAVKCEEELKDITFSEHKVNGKSKGQAYIEFTSQQAATATKHRIESQPAGEFQAGQGPKKHSVIFSSPATNPFRTLPKDTPGRGGAHNSQNRNASGSYQDRSGGNYNNNNNYNNNGGGYRGRGGGNMYNNRGGGMNNQGGGGFNRNFSGGNMNAFNSNGGGGPMNFGGNPMGGGGGGFNGNFRGNMGGGGMRGGPGGMRGGRGGGVGGPMGGMMGGMGPNMGGMNMGGMPGMNPMGNMPGGMGGMGGMNPMGMVGGGMPNFQGMHPNFTPNFFGGGGQGGQGGMVGNQGGGGGGNQGGGGEWQNPHGAKRQRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z452</accession>
    <name>A0ABR3Z452_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208310" evidence="1">
        <location>
            <begin position="20"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="181" mass="18857" checksum="EB9E829F4E93FFDF" modified="2025-10-08" version="1">MKFTAIASALLATAGLASASVCKHPSPPTCTLSNDNLIGANTDMSASQWNYQPIDSVPNLSHIQTCSGVANGCALFYTNPLPYHVYFSYTFNNAIPGAKYTYTISVLLEDAGLSQDIVLSNDGSSETSTTTVPATANAAPISLEFTAASSTVVLYVDAQNVYAGGLRFGNPSIVQTSCAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4C3</accession>
    <name>A0ABR3Z4C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="269"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="687"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="881"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1031" mass="114472" checksum="19C8926AF6626A10" modified="2025-10-08" version="1">MSRRVSRVVAALLFTFVFFSLQPFYRDAPLKVISHFNRPAGPVEEEAVDAPVEAPPASTPETNAPPSPLPWPPKQPVAPAPQLTPMPEPQSLPPPPRPIHPGSHSADGLSTHHHYYDNYILDLADTNPRKFTKDPELMAKYKSALQQFYDTLDEIRVVIQKCAVQNRRRLKNAKFQVPGVKDDQYNYDINYKQRRWAKLLASNLDHTPADEVQYRNRSKALKQQFWNRTELSDTTPFPDLPYWMANDEVIKADHGMQPPTAGPPLYHIWRSLRDYNAPGDGIHDATDGINMAIQANYRCASLDMDETCRTTEQTPAVVYIPPGTYLISSPIDILYNTQLVGDPLDPPTILVSSAFVGYAAIRTTVDDAHVPLGHAMRSVRNIVIDLTNAPADNSVMGIYWEAAQSSDLRNIDIYMRNNSDAAAAQTNTQIGLYFQNGRGCFLSDIYLQGGRVGAHINVEHFTVSNMIVADAQTAVVVPGRSRVGLDHLHGLTVVSAPGTHARSMRDDHVAKPDVAVGVAIDAIAASYILRGSLVLSDSVFVNVAVAISQVGYPNSNVDADHVEYKPHATTVLLRGKPGGTLSVPAWKLSVSKHEVVDKVFKETEIVEDRPVSLTVLTPGSKKSGSKTKASGSEDNSNRSWFSDWWDWWQGKLGNEEEADDHKEEHERNMLPWVTRRLPSYTDGHYEFVSVRDFGAAGDGKSDDTAALNEALESAAASGKVLFFPYGVYVVTNTVHIPVNSRIVGQAWATMEGRGSRFSWNTNYTAVKTEYNTTRLHVESQTLVPVVQVGRPGDHGVVEISDMAIALEEGRRALHLIEWNVGVDIDKPKGGAAMWNCHIRVPVGVAPLKVMDGSSAYLENVGVSIVKNKKATVLQDANYNFDLDDLPEEGEDEGEGERSKDRKDSERSEDNKEDGERSEDDKEHFEAERLKKVIDIWIKKSNREREHFLKDILIDGRGPAWVWGHGSNTVRLLPTAEEKGDVFLSGGMLKAVDVKVTMPKLKQPKQPKKGRFGSKGWAELEEAYDDENEHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4I4</accession>
    <name>A0ABR3Z4I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_005911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048401">
        <property type="entry name" value="SLS1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032741">
        <property type="entry name" value="Sls1_KH-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048748">
        <property type="entry name" value="SLS1_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048400">
        <property type="entry name" value="SLS1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14611">
        <property type="entry name" value="KH_SLS1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20777">
        <property type="entry name" value="KH_SLS1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20778">
        <property type="entry name" value="SLS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20776">
        <property type="entry name" value="SLS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLS1 N-terminal" evidence="3">
        <location>
            <begin position="70"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 first KH" evidence="2">
        <location>
            <begin position="199"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 second KH" evidence="4">
        <location>
            <begin position="300"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 C-terminal" evidence="5">
        <location>
            <begin position="400"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="804" mass="87994" checksum="8478022E062A94C8" modified="2025-10-08" version="1">MPTNHLLRQAPFSYFHSGRALHADNQQEPSTFNDIPLTTADADLVDDPLDENISDADAQKIWQSLLEDEGEPTAAEVYSYIDELRPVDETILSETAFRKSARELADGFTVAQLQGYIRKYRKPAAQPTVYPWEVRRRPWVPDVYGDDAMVDSKIKAVGPGSSLLLKGYIQRSMTNKERIVVQLMRECWGVSKRELMEAPGQLDVTVQELEFALLTVGAQTWLRDISTAYSTVTTTTATTNRSRSRSHSRSQTRHHRHIELLPARQKLRIFAPASTADAILAQIDTMLRAATTKQFNVADVARRSKGGITPAVLSAVGTLTGSWVRVNDEETKVLVSWVAPANRNPDLEDTGDMVYRMLLRAFGRTGLPAAKATSVLDYVPLQKSKSKAQFLTETDEASRETWPWEQRRGKWARLIEPAPLDASTARQRHEGTTTTPTDKALPMELTDSADNETHQKWYQVSQTSTVATFGRVLHAQPSESTGLLFSLEGAESDLATPVPEVARILSPVMPPLLGLSLLSDTPAAATPATPVPEEATEEATEEATEEETTATVEETTATPEESTATTPTTPATSTTIVLRFLPDPKTELASRAPPLEVFLDAVPGQRPVLAGLHAITATNTTDILFPTQPVDARITQRQFFALTGAEMLATAETQSQEGGTGLEPLFDLLTKSQLQLDGDAGQTGGAIVLATPLRLPALALPSEVLLSDQENDQVAIDYIFAGLEVRRRVATAYEGWTAALTSVEAGRGDGRWAELSLEAVPASVGEQSAGEQSFDASKESFRQAVGHMVHGDRVQWLMRHRQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4S7</accession>
    <name>A0ABR3Z4S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenine deaminase</fullName>
            <shortName evidence="7">ADE</shortName>
            <ecNumber evidence="7">3.5.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Adenine aminohydrolase</fullName>
            <shortName evidence="7">AAH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">AAH1</name>
        <name evidence="9" type="ORF">Sste5346_005418</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenine + H2O + H(+) = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01962">
        <property type="entry name" value="Adenine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028892">
        <property type="entry name" value="ADE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF6">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="14"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="245"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="403" mass="43906" checksum="C018448D7FA59E0E" modified="2025-10-08" version="1">MCHHTLHPLIAALPKCEHHMHVEGSLSPELLFALAERNRIALPPVSEDAAFASVEALYARYAQFTSLDDFLHYYYIGMSVLQTAADFEALAMAYFKKAHAANVRHAEIFFDPQVHLARGVSLADVVRGLRAASRRATAELGGMTSLLIPCLLRHLPVADSGTLVAQLREGYWANGDEAAQEEAVVQALDEAFDKEADADSLRGALAGLGLCSSERDLPPTLWRDVFREARRHSVSAPADTPQTTKARRGATRITAHAGEEGPAEYITLALDHLGAQRIDHGIAAATDKDLMARLAADQIMLTVCPMSNVCLKAAKSIADVPIRTFLEAGVPFSINSDDPAYFGGYIQENYCAVQEAHNLAAEDWATITRNAVRGSWCDDKRKQVILKEIDSVMEAFKAGTLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4V5</accession>
    <name>A0ABR3Z4V5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40624">
        <property type="entry name" value="BIOSYNTHESIS MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12025)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40624:SF1">
        <property type="entry name" value="BIOSYNTHESIS MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12025)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="122"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="225" mass="24836" checksum="DD9B151B5D9203BC" modified="2025-10-08" version="1">MPKLVFAILPTVGGQVRETQYISKLAATSAYSKANEPGVLTYSVCLPRDEADQKTIYMVEAYADQAAFDAHMQIPLVKDMIQWMGGPEPVLESAPTVLELDIVEDFGLFTRPDGVAAAADPYVVVGEVSYKDGELVEKSLAHWGKVVATTKADEPGSLVYALARNPAEPTKLYTFEAYESKEYLWETHAKSQAVQDNVAETKDWRAGLKHHIVKQVQGFLTRSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z600</accession>
    <name>A0ABR3Z600_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005153</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Nibrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10980">
        <property type="entry name" value="Nibrin, BRCT2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032429">
        <property type="entry name" value="Nibrin_BRCT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043014">
        <property type="entry name" value="Nibrin_BRCT2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16508">
        <property type="entry name" value="NIBRIN_BRCT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="7">
        <location>
            <begin position="24"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="384"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="619"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="683"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="687"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="745"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="758"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="778"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="809"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="843"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="863"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="884"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="923"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="967" mass="105124" checksum="2B58C4DF239FE5DB" modified="2025-10-08" version="1">MWLLENAGNAFEGRRLWLRPGKRYLFGRTRAEPGQLVISDKTISRKHLTIEVAAVRDGEGSDVDARSQVTVEDLATKIGTVVNGTQIRGTKHVLTEDRTTIKMGHMADLFTISWQPVVFSFSFTSKELRLTAPDDPSNPWTRLKRDLEPLDVKFLAEFRRDQTTHVVAKKRNTSRGLQALVSGAYIVTDSFLEAVTSSASDGSLESDWDAAWPNALDHLPPRGDEPSNRPSSTYGPDPRRANIFEGYTFVFYDQKQYDNLLPPISQGRGKAILLSGGDAVVPRQTEVDDFVRYVKGVAGEQGMGEFEDGSAGRGVVVVRYVPAKGDHVAWFTRFTTAVALRLDHRLIDQREFLDAILAVEPSMLRRPLEVEATPAVAMDMDVTASGDVAPSGDIDEPQRPPPPSMSMSQLSTATRRRGRRGVTTSRFKGFDADLASSDIDDDGGPVTNALAALDSNNIKPSQSQAHGDEDMFMSQQAQDNDPENEAPVRRSKRGAPASQKQKMAVADDDEDDVMDDIAPTAAAVKRRRIEAGHDPVPRVEDSEAEDVDDDIELVPKKEVAIKKEMTEADILDQARRNREAAEQKLAAERARLAELPDDGLDAEAIRKLTLVETIEVRKPAGRDTSRTNTTTTENGGSRWNPEWNGRRNFKKFRRQGDVVGRPPPRVIVGLEPAKTKEYGIGDGYWLEGRDDREERPDSIKRTRNGTPAEHTSALLTPSEILPVRDGRSSRRAPSHRSTSIDVDVDVVSVDAPSVDVDVVPDTDPEDGDEEDELGFPASPQPPPPPPPPPPTTRSIRLTRQSQRHHTGQDNDASLSAEATTSQPPSSDLPRTRAGKVGARTAAVRQSQATASQTRTPSGGAGGSVVDPSSMTSSSLVIFDTPPDSTQASTTSTAAETRNGRGSKRQPAAAAAAPPPAAKRPRRGAAAAATSSSISSGTLASGSTPAHITINDSDDEDDGLKFKFRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6D0</accession>
    <name>A0ABR3Z6D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21842" checksum="1DAB4D8B678112C1" modified="2025-10-08" version="1">MASSNNKDEFGYLRSLTSASDIEANLKPNPSSQQLQSAPPPSATTTAAQIRDDACPYDPVVRGAIPFYTFGRATNMILSLVVFWLGFVAVLRYDKDDWMNAIITPACAVFGFSCYDLYSVLRLSCRFPPHVRILYDGIFYGTGMAVASGFLTVWAVDAASDIGYSLSAPILVCLYTTTVIQYSICIEAVIEVIRMRRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z709</accession>
    <name>A0ABR3Z709_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004968</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="782" mass="86593" checksum="EE9C7EA48606E8BC" modified="2025-10-08" version="1">MFLTFDSAQPSAKDDICNAKEQQPTARRTEHLHRRRRHSTATVRACTSCRQRKIKCDGHTPCEACRWYKKAEQCRYVERERVRERETPNPPAQADYRGALARLFPEVDPDSIVGLSKEDLLSLLAKPTDGSHGSHGSHGAQYAQPQPQDSATVATSSSVETSPLFPLSLERPGLETLHSIPDQHDTRDEAMSGTDASATSDASDASEEHIDIADDVNALSLPARHLSSYLGVSSMQAALKVLVWLHPELHARLSSLNNRSHQQQSRKTYMPGLQVQATTEQQLLDAYFVHFQPLAPLMDEASCRATFLSGHRKDDRWLALRNILLALGSISISAAGVDSNHDHRAYFARSMRFLNFHVLGSPSLEAIQTLGLMGGWYCHYISQPNLAYALMGVALRMAVTLGLQHEPPLNTGAGAGAGYQEHKRRIWWSLCCLETWGQETLGRPSMDVFGASITVKLPQMLDKENYMTVLPLVENVHFIKIAFKIQQSLTALPTLAHADMDMDMLSLDTQLLQWWTSLPSVLKDYTPCPEPLLAARTVMRWRFYNQRILLYRPKLLNYAMCRIPVIAIKDEERIAVQRCGDIARVAIDDIAATTATAQKMSQMTQMLAWNAVWMIFQATMVPLILLAAAANNDDAEACKAYKAQVETAMAALDRMRPYGHTVERSLGMISGILETLTLTPVGGTTNNDPPLNAANSPLVLAGCQPVTQGRVPDWAAATVGTAGAAVAAGAQAPFENYSSQQMWEYLSWAENDVNDENSDFWHDLYSSWLPQEGASSSDARIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z765</accession>
    <name>A0ABR3Z765_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquinone/menaquinone biosynthesis-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF83">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="42622" checksum="24E3EDA5BCCE7570" modified="2025-10-08" version="1">MPPSKKDKSAARIPQQRAAPLPYRPSPSASSENTKQTGQQQEVQEQQQPTQQQGKQKKKEEAESLDSLFSKRKLPLVGAALAAGVLGFMIMPLLVTYLKGGCSENHQHASEVPPDAVPTGLPPIGAAAFDASLDVPERIMGIKNERKKLAKESKGAVLEVAVGTGRNVGYYLWDPASFTPDYVKSSRTATEDLLNGNRERPTITSYTGVDLSGEALGIARTQLRVTVPAVASAIPKKAAAIDDDRVAVGTEVVNALDGKVRLIRGDAMQPLPLPANAKESGVYYDTVVQTFGLCSVADPVKLIANMAAVVKPDTGRIVLLEHGRGWWSVVNSLLDKYAGSRFVRYGCWWNRDMEAIVSKAQEAVPGLEVVSVKQPGWLQFGTLWKIELKVAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7M4</accession>
    <name>A0ABR3Z7M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="128"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="403" mass="44458" checksum="51B010E2AD4F0314" modified="2025-10-08" version="1">MSVDAFTMPLSTEDLTLGWLQAVFSDPSISGFEVTDARLFETTSKLYVTLSYKDEKEASAAGKPQKVLLKGGFSPVMFATPGYKPILIRAYTREVDMFSKFVPTLPDDAVLQLPKVYWAGANDDNAILAMEDLAAGGFTFGDPTRTYSLDAVHSGVEQLATLHAKTWGWSTKEGEHESPKAAELAWLEPNIYDVTMGGLLGMWDELILGADRPPLPAILKDSRERTSRALSTYFASRNPRFRCLVHGDPHSGNTYLKGDDVRFLDWQIAHVGTAFHDLAYFLVSMLTVEERRTHELAVLDRYLEALARHGGPTLSREDPEVMTEYRKAILTGLGWVLTPHSMQAKARVAAMVERYAAAIVDHKTIELLTEIADAADKKTAEKTATDVKGNVAVQVNKVDGETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7V2</accession>
    <name>A0ABR3Z7V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046894624" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="28145" checksum="B5AE60AB60EABD50" modified="2025-10-08" version="1">MRAASWLALGAALLFSGEPVLASRCKPSPPASSSSSLPASSSSAAPSSPSPVSSISISPSAPSSAPSSSPSSSPSSTPASALSSVSPSSSVASASPSPSLCPNLVLNPNFAEGTDGLTSWGIVAHAQIEGSHTYGPSTDCGSNPGDPATCFESYNAASAKSYTYWNQYNLPVVPGQVYTLSFRYRVIVISGGVDILYGFINGNNLGSVTVSVATADVGVWHTFSTTTPWTAPSTPTTTYPDTSLAAIQFVNGDASAEVRIQFSDVFFNTCKEGSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8E3</accession>
    <name>A0ABR3Z8E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="29"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="238" mass="24810" checksum="AF51E2BE62A65FF7" modified="2025-10-08" version="1">MPFINISPHQELYYVLRSPEDAASSGLTFLFVHGLGSSSSFYATVIPALVAAGHQCLAFDMNGSCLTKYSGKDNSIQDHVNDAKALLNALSISSSKVIAVGHSMGGLVAGTLATELGLAGAVLIGAVTPSEAITEAFSQRIKAVEQNGMEPMADSIPTGATGSKSTPTHHAFIRALLLSQTSQGYVGLCRAIATAQPVEYAKARCPALLIAGAEDKVVPLAGLEKIKDRYSASKVKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9N6</accession>
    <name>A0ABR3Z9N6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytokinesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin homology family. BNI1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.150">
        <property type="entry name" value="Formin, FH3 diaphanous domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051661">
        <property type="entry name" value="Actin_filament_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014767">
        <property type="entry name" value="DAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102:SF2">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51231">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="5">
        <location>
            <begin position="306"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="6">
        <location>
            <begin position="1208"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="domain" description="DAD" evidence="4">
        <location>
            <begin position="1650"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="979"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1058"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1665"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="793"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="991"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1106"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1677"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1779"/>
            <end position="1798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1853" mass="202505" checksum="ACF314428E7BA41D" modified="2025-10-08" version="1">MSDKTSRQSSGGKSFFSRVKHKSDRRNTNGDEGRFLGPLDFDAQSQTGSRTSRHSHNRDSSIISLDRPTSPEAGINMMAGVMTTIPYESITADRRSPIAVEYLPKNGNGPPGSSHGQQPPSSSHGREPLPHQLNKATSDFHQYPSFDPSSTTAAAAVAASMYGAAPAAGSAAHLSNSSQLSGPRPPPGQGGNMTMASTGRQTQLQQWGPPRESAAFQNGQPPGSSHSHNSRYNSYQTTSAGRSSTDHASIFSALPSASSQSSYASHRESNRLTKFPSGVGGAGVPGGSGGGGGGGGTPSHDGFNLSKPEDDIVIEQMFLALMQKRGWLNLPEQARRQMTAYPPLKKWTLIYQDRLSEWQGEQRRRQTARPGQYQNFDVTTYSDEEGSPEWYVRKIMENSLDVKNLASLEVNLRTQQIGWVKRFIECQGQVALTNVLLKLNRKSARGPTAPDVPRGDKELDREYDLVKCLKALMNNKFGADDALAHQQVLVALTLSLISPRLSTRKLVSEVLTFLCHWDDGNGHVKVIQAMDNVKSTQGETGRFDAWMRIIEVTVDGRGKMGSMVGASEEVRSGGIGMENLLMEYSVATLMLINMLVDAPERDLQLRLHIRAQFIACGIKRVLTKMEAFQYDLIDKQVERFRSNEAIDYEDMLERENSSIKDNVEGDLKDLNDPVQIVDAIQARLKGSRTQDYFVSALQHLLLMRDSDGEERLRMFQLVDAMLSYVAMDRRLPDMDLKQSLNFSVQSLLDKLHTDSEARQALDEALEARQIAEAAMAERDEMRGRLELGADGLVAKMQRQLDEQTRFIDAQRRQAEALKAEIDSVQTLRAKEAQRNELETRELYLMLRDAQDVAASNAAQSKAGAAAVLATGGTINKSQLADEDPVRMQGILDREKLMDRLRMQIERQKTQFKLEGRVWGDAVGPSDRLRALREEMEGYGGDEAGVPGSLLGVDGGNAAAAAGLSTNSVLGSVNRQTKIGRKPIGGSAPGSAGVGSAGAGGIPPNAGGSHFDEDDDVTEDADGEVVYEKPRIVEMRRPVMDPKQQNGLLNEIVGKVKRYEGSDDEEGDGVTTGPSHPSLESQSPITPHDGDAPKIQITGAPPNNTGAPPPPPPPPPMPGQLPGAPPPPPPPPPPPGGLLPGAPPPPPPPPPPPGGLPGAPPPPPPPPPPGGKIGGMPPPPPPPPPMPGSMSGHFLSKQPTFEPVQPTVGLPVVRPKKKLKAFHWEKVDETVTTHWAAHTPSAEEREEKYMELSRKGILDEVEKLFMAKETKLLGQGTSKKDDKKQIISNDLRKAFEIAFAKFSQQSVDKVVQMIIHCDRDVLDNLVVMDFLQKDDLCNIPDNVAKQLAPYSKDWTGPKVSEETREMDPAELTRQDQIYLLTAYELHHYWKSRMRALALTRSFEPEYDEIMDSIRQVMEVSESIRDSVSLMNVLGLILDIGNYMNDANKQARGFKLSSLARLGMVKDDKNESTLADLVERIVRQQYPEWESFATDIVGVVTAQKINIEQLQTDAKKYILNINSVQRAFDSGNLSDPKKFHPQDRVTQVVLPIMKEARRKAEQMELYLEEMVRTYDDIMAFYGEDSRDENARRDFFAKLASFIGEWRRSKEKNVQYEETRRRNEASMKRKHAAQLKLGAGLGVGGNEAGALASPSSAGAMDSLLEKLRAAAPQTRDQRDRRRRARLKDRHQVRIASGQKIPDLNEIPEAEANLQSGGGGRGGLESPTSAGEGPPSVGSMLSPVIGSPRPDGGDGAGDEDDVAARAALLLQGMRGDDDDELDEEKRESLRKARRQTAEAERQSRRRRRDKAQSGGGGIAADSAPSGEATPSATEAQSAVAAPETVPEEGAPSVPMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q0</accession>
    <name>A0ABR3Z9Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="17261" checksum="54DCFD96DFAAF99A" modified="2025-10-08" version="1">MADIAAPQQGPVHGAPYPAKTRTATGAVNNVPTEVEVSYFRDKILVLVSQSGRLAQWIQVPLSAPSAASVDAALPLNSRTNGNPATGLLPSTHLTPRTLFGAGGESRETFGQLVAAQIGSLLALRDPSETRTLVVGLGLAGSQTGSTTDAQAQAIYFDVVDLVQKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q3</accession>
    <name>A0ABR3Z9Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024388">
        <property type="entry name" value="Ribosomal_mL58"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12824">
        <property type="entry name" value="MRP-L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28487" checksum="2A9F01F0C29E161D" modified="2025-10-08" version="1">MDARLLRRVACPATTMTSTARRAPSLFATTTSSTSPSSTSLIPHNIRIADRRYQSSANRTKRALNIAPHASFLKGGGGREKAGVGSSSGSSTQVAGALGTIENSSTTVLYNPPASAPSVYQTPFKFLPKSDPRRRQNLTTLFAKASSTTALSSSSSEPAAPALRHSNFSPAPQKYHLSERDVEEIRRLRALDPIEWSVHRIAQHFQCSPIFVMMVVRSSAEHRDATKERVAAVRARWGPIRSKARAERVKRREMLYNGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA57</accession>
    <name>A0ABR3ZA57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034443">
        <property type="entry name" value="PB1A10.08"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42051">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED PROTEIN PB1A10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42051:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED PROTEIN PB1A10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="587" mass="62989" checksum="A9D623B5BD534721" modified="2025-10-08" version="1">MSATVAAPRGGGSVADVRRLAKGDAPLMPFTPTKSLGTSQAGSAFVSDERPTTPTSPVQIPVKAARHETAHAHAHAHTHAHAHAHAHAHATKHRHHQPPNQDAWRNFRQGQSQPQAWGTGSRSRSHDVHSPDSISPSVAALLAVTSIPRSRSSRSLRQNRNANSERISEKRMTVNSFIDQVQEAEQEFSLSLSKSPLDVLLTAPEDLEDDDEVSISDSTLDPDLSTRTVSLESMPSLADSFATGTISSYDSPRTPNRRYGSVRKARPTRRSLTPVSSPPSGGHESDPLSAASLDGGSDSEVDVDSLDFRVFQSPPDPLAKTTEARFPLQPLRSAFKSNLTASLRALRNAARSFSSLNLTSIPPEDFLTRSILTIDPRIPYTDERRPPPLEEEPSAALRRYLNPTTGPHIDPRLSAAQMLSPALASASLSPVTLTSSSSGPSSSTSGGATSPGSSPPRSPFTASIQMQTYRVHRTKGSRSSTSGSYNGTTPSGLPLHPSGRSASSTALQEADRPPPGPRQRELRENSDFIRIAVMEMAMRRVGKLDDRKPGRARLALPPRKMGAKPYVVGTDGVPARWVSIVVSSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAH7</accession>
    <name>A0ABR3ZAH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like-conjugating enzyme ATG10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004065</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="264" mass="29012" checksum="08FD780AD38D9BC2" modified="2025-10-08" version="1">MAAPLNMDLSLNLNINTGVVASSSSSSSISAHLDEFRDYPFLANDEFNEVCHEFDRIYRQATLGPLRRRWRVSVCTAFNTSFFSDSESTTYLQITRPLESSAADDELAGVLNQFSFGEASDMVEDSTMAMAEDADEAALKAAPPTANYGYVTYEVHLHPTYRAPCLWFSLHGLPNGESPLGIDTVFRHLVPEQFQDRLRSMGSVGGISADYHPITGVPSFFVHPCLLGEAMTGFSCTKKSYLMVWLGLVGGCVGLWVPKEMALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBC8</accession>
    <name>A0ABR3ZBC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="268" mass="29247" checksum="C272848C45C18EAA" modified="2025-10-08" version="1">MDIDVDINSRDCDDPGGNVDDITVTTPMVTTPMVGDLDLTTTVRDDVSSPFVFHRSVASPPKASPSSASKKAVVSNKTLRGRILKKANAKAKIMDGNQFKKMLAGHPGPSTMESTTASATNGIEQRQEMANAHAEQIASGDTDIARLKYQINDLSKMMYDLRHENWALENRVTALKATVLTNEEQLLHTSKMEAKLDHALRYIEALKKQVRSYGGTVFADGMEGFADSVAQDGDDNSEDGDIPAYYPQAAAKPQQYTALAIQNRRALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBF7</accession>
    <name>A0ABR3ZBF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="130" mass="13386" checksum="78EE0CC29EA75094" modified="2025-10-08" version="1">MTSFHTYAQAAAVRAQHHHGASNPTRILLPVVVIIALLAAALLPSDESSDGYSPLLLLIRQTIIITAAAIGIPGSLCSIVLYHAGKRDELGYLCVPLGLASGTVAAAVTLAQNLPLESSPIVSSGGVRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC16</accession>
    <name>A0ABR3ZC16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003699</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42986">
        <property type="entry name" value="BENZALDEHYDE DEHYDROGENASE YFMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42986:SF1">
        <property type="entry name" value="BENZALDEHYDE DEHYDROGENASE YFMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="491" mass="52112" checksum="A4B3FA94EA921C4C" modified="2025-10-08" version="1">MAESTANLATFGLVINGENVDTAADTFPVLDPISQKVVHYAPAATEAHAQAAVAAAEAAFETWRETTPIERRNIMLKAVEVLQSRQEELVRSMVEETGAKPSWAAFNIRTGLGFVQEAAGMTTQIKGDLLQSNDRGTLAMVFREPCGVILGIAPWNAPIILGIRAFITPLICGNTVILKASENSPRTQYLLVDAFRQAGLPAGVLSFICCPRTSASVVTEAMVGHPAVQRVNFTGSTAVGRIIAAMSAKYLKPTILELGGKAPMVVLKHANVAEAVRAAAFGAMQHQGQICMSTERLIIHKSVAAEFASLLKAKIDSLHAADPRTDSTAALGSLISPVAGSRVEKLVADALAKGATVHGGRYSVDGAIVQPLVLQNVQKGMDIYYQESFGPTVALFEFETNEEAINLANDTEYGLVASVFGNDIQDALAVARRIRSGSCHINGPTVHDEPHLPLGGQKASGYGKFGGTSCINEFTEERVVTIGSHGHNYPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC35</accession>
    <name>A0ABR3ZC35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="60888" checksum="57C77B2C75F54D5E" modified="2025-10-08" version="1">MSSQAKMESVVGSVEKHEDVNTTATTDAVDNNLDKHGGVTLKSDHDKLGLRASAWKFKKAVLICNLLCIAAACDGYQINLNGNIIANQGFINHIGFANDKGVYALKAQYTSLWGALQSLGQIIGMLLLNPVSDRIGRKQTLYILWAILAASVAIETVVRDWRDWAGAKLLAGTGIGALQVTLPVYITEWSPVNIRGAMVLTYGFWNTIGSFLAPLILTILQSVDPLNYKTAILTQWGFLGVMLPIFLWLPETPAYYAERDQDDRGKAALRRVNGGVLGYDVDAEYAVIKHTILEERRVRHEYGLDSKNLKDVVRTYVACFRGTNMLRTFGAALPACSQQLTGLAFLNTYASLFFKQSGFTNAFLITTILAIIQLVSSVFLILIADKAGRRRPTFISTVGCTLALLIVGILGFVPKTTAVRGLLIFVACVWAFFSKALGSIGWAFVGEVASQKLRARTAGVAAAASVVFGLTFNTTVPLMLNTSGANWSYKTAWLFFGTGVAMVVIIFFFVPEPSLRNAAEMDEMYEKKVPPRKMRKYVTDVQRAQASDVAMAGVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCU5</accession>
    <name>A0ABR3ZCU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Galactosyl transferase gma12 mnn10 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003949</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 34 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="454"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="59323" checksum="3A9DEB8EB333AEC0" modified="2025-10-08" version="1">MLVQQFQRPTRLLAVLTSICLVYLCFNYLQRVDFATTCNTPVRFGEQQDVDGQFGVTRMLGTKPATMPKGPMAKVAKVGVAVNALDIPVVHRAFKTHQYHNDLHGYPHFIADREVVSDLIDNDRMHRGSGAYTKPAYLLAIIITELLKPESERLEWIFWFDGDTMILNPSTPLETFLPPNTSDILNDVHLVIASNWDGLNSGAFALRVHPWTASMLSGVLAYPMYEKERTLKDRFRDQSAFQFLLTHNESPLARDALKHKNHWAEVPMRWYNSLPVNNAFFADGKWLFSHNMSPAMFDNGTTEVFDDGRDGKIQPWKVMQGDLLVHFAGTKGVRDSWMKPWLDRAEALLPEWNNPNHTAKLQVEVAQFWQDYEGVMQERVAAAKEVEAKENQRKKEDEKRKFEEKKKAEERKQIEKEKKKEEQRKKDELKQKQLEEKKKAAEEAAKKKEEEEAAASASAAAAAKTAAAAAAESTSSSSDPSDSSSDSATSESTSSEETSSSEEKSADSESSPDSSSSDSSSDSTSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDQ2</accession>
    <name>A0ABR3ZDQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GTR2</name>
        <name evidence="10" type="ORF">Sste5346_003213</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the GSE complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="47862" checksum="11288AD88A013B1B" modified="2025-10-08" version="1">MPLTSPGRRAPAESSSSSSSSPSSPIDSPLRPDPAPTPTAPASAERVTSPALLNLERVYEQNRQRTQKRDGGGVGALGPGAQVPAAASTGVKSPEPTAPAPPKGKPRLLLMGQRASGKSSISSVVFHKLPPNETLFLESTSRLQKDAMASFMDFQVWDFPGQIDYFEASSFDMDAIFGEVGALIWVIDSQDDYLEAVARLNNTILNVQRNYPNINIEVFIHKVDGLSDDFKMEIHRDIMIRVQDELSDQGFENAPVNFHLTSIYDHSIFEAFSKVIQKLIPRLGQLEAMLTSLCRTCRFEKAYLFDVLSKIYIATDSTPAEMASYEVCSDFIDGIIDITEVYGSWARPEAYHQRLEAEQHQPLADQIACPWAESCIVLADGSKPILLREVDKYLALVAVMKEGSYDKIPLINMNVDVVVKGLTEFFKITKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDR9</accession>
    <name>A0ABR3ZDR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_003195</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EFG1/PHD1/stuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029790">
        <property type="entry name" value="EFG1/Phd1/StuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792:SF1">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0183">Conidiation</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="10">
        <location>
            <begin position="206"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="319"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="465"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="563"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="685"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="467"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="580"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="712"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="727"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="774" mass="81885" checksum="3BE57DFEB506666E" modified="2025-10-08" version="1">MNERLPSLPFPPSAQQAYSSGTVSPRVGSIGSSTSSSADSQSPYTSVASSHGPKTPPSTTVLPSVPSSLSGGLHTPIVQSSIHGYDQYQHAMNQGTAEMYYQQQHMQGGQQQPPPVTSSAIAQYTHQQPPLLQPGPAQYPNPSPYNQYGYTNGLTSPPTAAPVANPLAANPHVLPLPGVATQQGMQNNYSGFDTTGQVAPPGMKPRVTATLWEDEGSLCFQVEARGICVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLFPLFVHNIAALLYHPTNQNRTSQVMAAAERRKQEQGQMRNGQAGAPGLPSLQHHSTMALPGPQQTLPSHANMATPTGRPPLDRAHTFPTPPTSASSVMGGGMSASEPFSWPQQGVNGAQGNNPMSIDTSLSNARSMPATPATTPPGPPMQAMQQYPPTTQAYDASRSMYHHQTPAPATQQPPSQQHTPHHSQQQQSHGYPGSAPNSSPHDRNNMYGHNAVAAAAAAAAGGYVKTEMSAPATNRSSIAGPSGNEPVVDNKQQTNGLLQHTHNGHAGDGVSHGGVPEDEHDHEHETEYTHDSSTYDASRAQYNYGAPQVATLPSEHSHLSPDVAAAAAANHQATSGRSTPRSAASQAYYAQQGYSTPPRTGGAATAATQASSNLYNVVTSDRGNANGAPTQDVYAGPADLPGALPNGYTTPTLNGTSTGMKRGRDDDDDRSSMDMKRRKTLLDSSMPSAVYDASAINRAAPPVGAPRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEC0</accession>
    <name>A0ABR3ZEC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004780">
        <property type="entry name" value="PRK06126.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF21">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21274">
        <property type="entry name" value="Rng_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="12"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="631" mass="70102" checksum="B2DAB9DE0BC03B22" modified="2025-10-08" version="1">MSSTQKTAPPGTVLIAGGGPVGLFLAHTLSFYGIPSILFERNSDTTRWPKMDLTNARTMEMCRKLGLAEGLRKQGVPSHIDQDVLISTGLPAREAMARWALPGVDKCRAEIMACNDGHLPLEPYQRISQAVFERWLRGICEKDPLITLHYGHKVENCEETEDGAKLTVSTDAKTTVWSSEYVVGCDGGSSRVRRSLGLPLDGGPIPACAVLVHFKSRDLTRLHRQGRFWHIFVIGPSGSVEGALIAQDEIDTWTVHWFVPVDTDTDQYTSEQVVARALGGLHGDYPVEIDKVLVRSVWRPNIAVARQWTSPLGKVFLAGDSAHQNIPTGGYGMNMGIGDAFDLTWKLAAVLRKEAGPGLLQSYEPERRPVALRNVERSGVHFQVHMQLKDEILKDTSPQVACEEDSETGQALRDKIRLHYEAHDGENKDLGIEMDYRYASSIILSDKDTTTKEPSWEPRQYTPSTWPGARAPHVFLKDGKTPIYDLLGKWWTLLVFADSEEEPLGQDILAEAASAANMPLRVARLVGETHAAKLYERRLVLIRPDHHVAWRADKLNNKSVANDVVQTVAGWKSNGQQREKTNGVNEVNEVNGTDSTNGTIPRKPRESFTGTTTMQTQVNEFKMEKQGAFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZED4</accession>
    <name>A0ABR3ZED4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="51309" checksum="080D596315B97C06" modified="2025-10-08" version="1">MATTPIVAATPSPPPHIHTPNTPRLGFADSWEPFSPRKSSRIAAASKNNSSSNNTSRSASARTPSPSANVRRAVRPPRSPKVSKQAPPQAQHSLQQHPQHLDIAAFSPAPTPRKKRAMPTAHFLSPEDAFKSNKKAAAGESSSTFSRMGAGMLPTPAKTPSKKVHAASQNESNIAAIARNLFHHNDVDEVMASPSKTPSRKGKKYTGFSLESFAVVEDEEPIPIFTDSQDRVPEADSSAENPFFGDSAAAAAAAAPSTSTEPARRRSKRNQVSIPGEGKLTVEEATRREDGLVYVFRGKKIFRKFEDAADAQEEDILDGMGSSNGGKGKRMTRSAIKPRLLFPREDSSFTTETTPNGGSTEDEEADTDIEDGNLVGGDDEEEVEEEDIVEDEHALTSAPNTPPPASKYAAPASPPTTTRARRSGHKAAEELTPKAVAPKKRSPFDGWRQTKSSASAVGHKRTVDALGSSPTAAAGAKRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF63</accession>
    <name>A0ABR3ZF63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_003595</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0749">Sporulation</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="10">
        <location>
            <begin position="29"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="200"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="353"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="538" mass="57310" checksum="301AEE3497B5ECE8" modified="2025-10-08" version="1">MSGHLHTAYATQFGDHTIAPPPAAIKVEDSVPDYMLEIRQQPQHARVALGKDKADRKPIDPPPILQLKVSHKKDPMQNFLQSPYYFMSCSLLKGDEASSKEPLPSYLIGTVVSSLHRLKDTDNQDGGFFVFGDLSCKVEGKFRLLFTLYQMQKMECVHITSIVSDTFQVYPTKSFPGLAESTFLTRSFSDQGVRLRLRKDSRSMTTRKRNATAAEFARKQQDPRDTGRRSIPTRTSSADDNLPYGATTTNSGFDPHAATAYGHYDPDSAGLGSKRRRLVVDDVPPPPPPYTSGVNSVATGADLSGYGAPRAAYHNIGMPVSSSPYGLPIQTTAATLGYSHAGTHTHHQLNRLDTQQLGGPHGPGSAGQGAFQSPSSRHSPQHAFQYGALQASPSSMGYQPSSAASTSAGHGLTGSPAGDYRPHPGPIYTSNVSADASPRTHATPNPNNTTPSGTSTSPPDATANYTAAAATGAMTPYTQSIGSYSYAQALGDPQSHLSSTARSNGLPSLDLTHHVNGSGLGLDLGYGDVDRHNTGQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP5</accession>
    <name>A0ABR3ZFP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="37022" checksum="820B418BC45FE7C4" modified="2025-10-08" version="1">MQNTNPFTRAVVEEMRTMYPEELADRSWDNVGLLLENSKLPTDKPGRERVLLTNDLTPDVVDEAIAYKVSVIVAYHPIIFRGLKSITLRDPQQASLLKLMQNNIAVYSPHTALDAGVDGINDWLADTVRSAGRELGATDAVTTVVKSVSDRMPPFYKPVDAEGNKLDVGYGRRIGLNKTVPAGELIKQVVKEMGLNMSHVLVARPRTQTQPTRTDRDGIYSVGVCAGSGFDIFRDQVEMVNMIITGEVSHHDALYATTRNVWVVCLLHSNSERRFLSARLQDQLTRQITQHAAYKDAAVLVSERDRDPFEFWEVDNPPTQLTSDRPEAFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG89</accession>
    <name>A0ABR3ZG89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN FLCN/SMCR8-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="2">
        <location>
            <begin position="308"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="57264" checksum="8BF26C08CA174108" modified="2025-10-08" version="1">MVTEGLPVKCNSCDNGDVPDLMSAVASAVSSVTSSPSSSSTPHAAATAATVAVADALRKMSLGQPSRRSLADDEDRPRSSTDVPTPRSRPDATSAPHRSPRTSTSPRDPQQQRAQAQAQPIPAQQARADPMTSNFRKTYDDSVTKRAIPCDNCAMTLPRSNNNSRVSNNTSSGGSSSGGASGSSNTDARNPTLRTRVPCARVYDGAPGDASPRLLHPSSSSASSSTSSDTEGDERPSAQLYRNHHRRTGTMTSVGTSRSSTSSSASHLMSSHTHYINYTSTHEPVSANAYCIIRASCLRTLTLETLPRSPASSAMAAGGNIYATTSQPTTPSPLAATSYFTSNPHAAASASAAAAAAANGGPLFFGDPAAGYTTAHVFRVADMHARGHKRVYALIALNTHRERMAMKAFGFVSAAFNDLATWIQQLADAEAERVALHNESTATSSPSGDGSPSTSTNPAFGFDRSPHVSPPPTQPSSVANDSGSSFLVAAGNGLSRRMGPGFAGFGGLGSSAAASLRARGLPEILGMPDFFIELHARFVRLLLELGVALNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGD1</accession>
    <name>A0ABR3ZGD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear envelope pore membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056541">
        <property type="entry name" value="Ig-like_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056542">
        <property type="entry name" value="Ig-like_POM152_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056543">
        <property type="entry name" value="Ig-like_POM152_9th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056544">
        <property type="entry name" value="Ig_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037701">
        <property type="entry name" value="Pom152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056540">
        <property type="entry name" value="TMD_POM152"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206:SF1">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24312">
        <property type="entry name" value="Ig-like_POM152"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24519">
        <property type="entry name" value="Ig-like_Pom152_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24527">
        <property type="entry name" value="Ig-like_Pom152_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23664">
        <property type="entry name" value="Ig_Pom152"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24097">
        <property type="entry name" value="TMD_POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoporin POM152 N-terminal transmembrane" evidence="3">
        <location>
            <begin position="89"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 first Ig-like" evidence="5">
        <location>
            <begin position="225"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="4">
        <location>
            <begin position="531"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 immunoglobulin-like" evidence="2">
        <location>
            <begin position="641"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="4">
        <location>
            <begin position="845"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 immunoglobulin-like" evidence="2">
        <location>
            <begin position="971"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 ninth Ig-like" evidence="6">
        <location>
            <begin position="1194"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="4">
        <location>
            <begin position="1277"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1153"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1380" mass="150922" checksum="89FA6AADE8AF9CF3" modified="2025-10-08" version="1">MSATPRVRSGAFPQTPTTIRVGRGAPPTPSPSPPVDDIPTKRSSSSTSSRPVFASARSSNGSTRGSAAAAAAAAGSAAPGPLIPLDIIDAPTQRFYAVALYIALIAWKCYDWVQLLEENGESFWLFLKWIGLDFVFLFGLPEMRIPWLELSQPVAIFLFFCHVITDYLLMFNIGVPWHAWFLSLLKVFYDRELSISEHYVKASSILQNSSLISGRQIINILPEGSAILNPSGLPFCIGGLGGTGVAAGANPNIANLPLYFNATIPAEVELIRLDLDSNEEETLRLTKNQLREIAKLVKRQEASADGTLAAVRFDVPVKKTGAYRLGRVLDEYKLDVQRPSPFSFVVSCPSARVGGGGNLPSKQSSWSSSSSSGPITRCHGDLSDLLLEVDGTPPLKIVYSRTINGKDHSFHFQSLQPEGFVSPLLGTVPSRSAGLSASASSGNSQESLDSDAVVAANFPTEGDADISWARSRRVSVGLNETMHVGGEWRYSIDEVHDAFGNVAKYNEPVEDHEVRPRPPKHLIQSFHVRERPRIRLQGCDLRQPLKVARGKSTQFPIRYEIPGVRRPEDGSAHTLTWQFSPIDTLTKSGDHGDVVTTETFNARHADEMPTISTPGLYTLKSVSSGSCEGEVQEPASCLLLNPLEPKLALRSEGIPDSCGGNSIGLRVDLDLVGTPPFLVRYDVSSNGVVRHEKVSVSGMRYQLELVPRVAGNHKYIFRSIDDAVYKSQPLSGSEMTLEQNVKPAARASIDHPTGKANACLQDSVGVDIALSGEAPFTLEYVLLHEGKRRTFKEENIDKYRYRIETPALAQGGEYTLALTSVHDRSGCRTFLQGGGELKIAVRRQRPRAAFGLLENKRRVFVVEDAAVRLPLRLTGEGPWKVSYRNLGKEFGDDGKPTHPGPLVTRSLKSGNDFLQVSERGTYEIVDVADNQCVGLVDNTASVFDVDWFPRPKLSFVQTEAIQEQGNLFVKQDVCEGDVDGFEIDLRGSPPYHVEYNVRHKAAKGSQTSFIHKQLDAALGRASIQMDTSKAGTYRYEFAPPADSLYNNNRPSSGSKGGVSPLVMQQTVFAKPTAAFAKAGQSFKYCMTEQDNEDLIPMVLTGVPPFYVEMEIKHQSGAVSETYRVPSIMTHNYGLQIPRQHLRPGTQQVRIRKVRDARGCQQKTDDLVGGNGNSASDSLSSSSTSSVQVQLFEAPAIYALESRTDYCVGERISYTLSGTPPFDVWYNFNGVTRKGASATTTFRRVAEAPGEFTITGISDKASECRAAVNLSRIIHPLPSVRVSQGRTARVDIHEGGAVEMVFEFGGTPPFEFTYTRSTNARKGQRSQVLETRHDISYEMTKTVRASQEGTYEVVAIKDKFCAFSTQRGAEGADSGSGKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGN1</accession>
    <name>A0ABR3ZGN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625:SF2">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32322" checksum="008E259C237CD48B" modified="2025-10-08" version="1">MSTVQLSFNLRVSSSVKTVHLLGSWDNYVGQLPLSKDKSASKSGSWKGTFRFQGNTLEAGQRYWYYYIIDGYHASHNPSEKSTLEPTTGRELNVLDVPKAKSSSSSKSSSSKTSSSHKSSSSSSRHSSKDKKRSSHAEIPKGRPLSTSQIKCPKPQSPHATRNILTADYDLSELSEQFAATGFEDDEYNANAVVYDGDYAEDAAYVTADYGVLSGSDLSYSSDDASSVSSGAHSSMSGYSTPGSDYSSCTCERYGITRKGDRVRIDCGGARCGYDDECSSSEDEEICATSSRRNGIIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGV7</accession>
    <name>A0ABR3ZGV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RAS2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ras2</name>
        <name evidence="4" type="ORF">Sste5346_003181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="232" mass="25934" checksum="8CCE6F34DA6E40CE" modified="2025-10-08" version="1">MANKMVLYKLVVLGDGGVGKTALTIQLCLQHFVETYDPTIEDSYRKQVVIDGQACMLEVLDTAGQEEYTALRDQWIRDGEGFVLVYSISSRSSFSRIKRFHHQIQRVKESTASSPPYPGSPLAAANSQAPVPVMLVGNKSDRVTEREVSTQEGHALARELGCEFVEASAKNCINVEKAFYDVVRILRRQRQQASRPVAPSGGNRRPEGREGGSRRTDSERYRRSKSNRCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHG9</accession>
    <name>A0ABR3ZHG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal membrane protein PMP27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PEX11</name>
        <name evidence="5" type="ORF">Sste5346_002721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="243" mass="26977" checksum="9AADFD9CDECFDCBC" modified="2025-10-08" version="1">MVADALVFHPTVAHYLRFAATTVGRDKLMRTVQYFARFYVWYRLRTNATTAEVAPWAALKGVLGKARKLLQAGKNMEHFKSAVAASQDPKLSTAAVGSPVLRYATVGRQLSYASYLTIELVLLPETLGVRKLTNRTLATRLKRDSTRLWTLGLLCSVFAQLFTLRRLKEREARIDRKDGEGVVESKRIAKERQASHLQLICDAADLTNTTSSLGWTNFDDGVVGLAGTASGIIGIYNQWKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHL4</accession>
    <name>A0ABR3ZHL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="25097" checksum="3F62C55A92B8D0F4" modified="2025-10-08" version="1">MSSSGKPSSMNMFRPEKAEDWEDFREVITALYQNNTLSEVIVQMKTLHFFSATPKQYKTKFKEWGLTTKYVKGAEYEELLEQEEQDEYNVRGKRVSHQDVARFKRRREKSENKAKSGGGKSSSSKGHGTRGEAASGSTATGYEYYDNGDEGSSGAYMVASGDYMGYTTSSTGGGGAYITADGTPVTTAASYGAYAYDTTDGAGEVYDPNLEGGYQQQQGYGSGSTANWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHP4</accession>
    <name>A0ABR3ZHP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="180" mass="19625" checksum="702AB088207203D0" modified="2025-10-08" version="1">MSSGPSFPTGGLPAEFTPQAYPLPAPSLQPDFRLVCNLAQRIPVGPTPTGGQRNWIGIADGWFAGKWGSGTIVPGGQDNQVVTPELSTKIDTQYLLKTNDAEPAYITVHTEGWRTGNKEVLAKLFDPTLADGVSPEEYSFRLYVHLETGDARYKHLCTVMWVASGARLGAKVIYDAYRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIB5</accession>
    <name>A0ABR3ZIB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="46093" checksum="0329CB3B409935D3" modified="2025-10-08" version="1">MPRLGYSKSRTGCLKCRQRRVKSSRSQSAAGRRSGSAAAQSVVSPVVAAAVAIRPDSETAVSGSEAARSGSDAGAGQSPLSGTGHLIAGPPSSSASTNIPPDGVTPPDRHHLWATDMELMHHYSTDAFRTMPRAEEVGQTWLIDAVQASFQDDYILHLILAFSAFHLAHLRPHRRPYYSYIAVHHQDLGISRMRASLAQLDAENCHSLFMAGSLLAVSTFASLAIHAGDKSYERPLLDEIVEVFILIKGMGVVLDVWEKTIQHGRFRELFRLTKPSTPPPVFWDHMRSQLEQLRKPLADRMLDQPTVLDCVDREIGNLYELTSSCVMTSADPELRLVMVWPIQISDAYLTLLKEKVPAALVVLGYYCVVVDRSALRNWFTRSWAREALYAINSILPPHYTELLRWPLDQVSVATPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIM7</accession>
    <name>A0ABR3ZIM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039297">
        <property type="entry name" value="COX7a"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02238">
        <property type="entry name" value="COX7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7550" checksum="B2A9C3B6057018FB" modified="2025-10-08" version="1">MGIFNAPNKVPQHQRAYQAAYRQHIRIWNISPRSRVMLVPYTILLTGTLGAGLYGMGRKVLGYGSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ08</accession>
    <name>A0ABR3ZJ08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048889">
        <property type="entry name" value="NSUN5_RCM1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21153">
        <property type="entry name" value="NSUN5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="7">
        <location>
            <begin position="166"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="395"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="504"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="285"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="640" mass="68632" checksum="E64EEEA985155A63" modified="2025-10-08" version="1">MSLYHEAAAALTAPASDGGNLKTRIFGPRSKDVKDVQAAKGKELKEKSGRRATSVIPPAQIYALAAESCKWSGVLSEVIDKAGLLEQERKAKLTPILSILLVHDLLIAKNGNGNIQLPEHHGLRAAVERHKARLSAELTRARLRRRAHTLASLREQVEKAAAASVSETSSLAAATRWVRINTLKTTLEQQLDTTFAGYEKVSTLKELFATDADGPRLYIDEHVPNLVAVPLVTVLSASSSVQTDLTRCDAYKRGAIIFQDKASCFPAYLLDPASVPGGGHVVDACAAPGNKTSHLAALLGEEKTPTDRRVFAFEKDKYRSKTLQNMLSKAGALAEGEGESVSIATVDAGQDFLKVDPTAERFRDVRALLLDPSCSGSGIVGRDAMPELFLPKAAKTVGGGSSQQAKPTSKNKNKRKRGGEAEPKNEKPTPTDVSSAIDDLQAKDDPKARLAALASFQLAILLHACSFPSAQRVTYSTCSIHAVENEQVVVRALRALRQSPTTSGWRQLRRDEQVSGMQAWPVRGDPKGAENVPRTDEDDDDGDDDEDAAAVADACIRSYADDDCGVMGFFVAAFVRDEEGAGPSTNGASTTDKPRQANGEATKKASKKNKKKKKAAAQAQPVVEAAKDDESDDDWGGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJT9</accession>
    <name>A0ABR3ZJT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002046</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="49"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="623" mass="66724" checksum="C7EAA554D8896ADB" modified="2025-10-08" version="1">MTDEIGPAPDHAYPGVTDLDQEVKQDELRSQALAAEVDTLPQGYYSSWRFLGTFAGTAFNLAGTYFAFEAAAGVISIINEDIGPSTNGYLFSIVWTIAQAISILLFGRNSDQFGRRNIALAANVIGIIGGIVAATAQSMNQLIGANAVLGLAAGIPGSYPLLTGELLSNKGKFLGTMIVVVPNVIATGFGPFLGARLAHLSSWRWIFYIYIILMVIGTALWFVFYHPPSFVQMHGEKHSKRHSLANIDYVGTILLVAGLVLLMLGISWGGTTYPWKSGHVIGLIVSGGVTLVLFVFYEIYRKQRYPIVPMHFWSDVRGFTCVVIISSITGCLQTALFILWPSAVSFIFGSSSTGWEQIGWMSSVVNLGAWAGIMIIGPLYNTVKHLKWQLIVGSAWMTAFLGAGATIAASRKGQSIAVSFLASFPMGWGEIFTMLMVQYIVSESDLGVGFAIVSASRVVLGSIFSSIFVAIYTNKLPGKYESIVVPAVEGAGLPASSVPALLTAAGAGTQDALLAVPGMNSSILQVANDSISEAYSESYAYVFYTAMALGFVCLIAALCLRDFDHYLTDHVSRQIYHREQTKVDILAAKGLQPSSDMDAATTATAGSHEKASTSNHEKAEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM6</accession>
    <name>A0ABR3ZKM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">15-hydroxyprostaglandin dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30141" checksum="CF75B005A3AE84FA" modified="2025-10-08" version="1">MASTKPVALITGASSGMGAGFTRDLVQKGWNVAMVDLKASPDVQADVGDAATFYTGDVSDYDSQAKCFQAAWDTYGRLDLVCLNAGIIDRSPLYILQHRNSSDIPPAPDLKCTDVNVKGVYYGTQLAIHFMRKNVVPGGSIVVTASASSLYPHECYPEYSGSKAAVWNFVRASARVLRIKDNIRINCIRPGFVPTSLAPPGMIKAAEDIITPLETIVKALNKILDDKTLSGAALECSMDKILLTPEPEFLNGEASARASFLWEPGFVAMHGEASQLPEAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLD9</accession>
    <name>A0ABR3ZLD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Histone deacetylase</fullName>
            <ecNumber evidence="3 10">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HDA1</name>
        <name evidence="14" type="ORF">Sste5346_001957</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019154">
        <property type="entry name" value="Arb2-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017321">
        <property type="entry name" value="Hist_deAcase_II_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09757">
        <property type="entry name" value="Arb2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037919">
        <property type="entry name" value="HDAC_II_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="12">
        <location>
            <begin position="111"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Arb2-like" evidence="13">
        <location>
            <begin position="489"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="760" mass="84405" checksum="2DCC1325627864FB" modified="2025-10-08" version="1">MEGADNDVVMDGMERPRSAAPVVASTEAAGTNSFSTKSNGNSNGGSSNGNNNPSTGNEGDDDDNLDDDDDEDDPMGYPVDFKRRGLLPTGCCYDDRMKLHANADFGSGPHHPEDPARISEIMGAFKRAGLVFNGSDADLIKIIQKCPTKYMWRIAARNATEEEILLSHHPHHFQWVKNLSEKPTYELRFISKTMDEGRDSLYVGSMTYEASLLSAGGAIETCKAVVRGDVKNAFAIIRPPGHHAEYNQPMGFCLFNNVPIATRVCQKEYPDLCQKVLILDWDVHHGNGIQNMFYDDPNVLYISLHVYSDGQFYPGAPADPSVPDGNIDRCGINEGLGRNINIGWDQQGMGDGEYIAAFQKIVMPIANEFNPDFVIISAGFDAAAGDELGGCYVTPECYAHMTHMLMSLASGKVAVCLEGGYNLEAISASALAVARTLMGEPPPKFEIPKLRKDAARLLARVQAHQAPYWECMRPGVVDVPDLQSQGALRLHDVVRTFQRHVLSQKHGMFPLFIQRSAIYKSFEGQVLVTRSLHTAKKIIVIIHDPPELVAQPDVLDNSLDSHNSWMNDGVMSYIDWAIGQGFGVIDINVPHYNTQPEDNTSESFIPRISEEVMQSQIQELVCYIWDNYLQISESAQQIFLLGVGNAYLGVKVLLVNRDCKSRIDGVVNFVNGSLRAVKSDADPDLTQWYKTHSRVYVGTDHACWQTSEFTRKINKRRFGDVVRSPFMGLSRMLKEHAEDAREWILERLPETEGNTTEDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMM3</accession>
    <name>A0ABR3ZMM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001662</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF26">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="430"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="591"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="430"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="600"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="744" mass="82275" checksum="695C086D9D7A905B" modified="2025-10-08" version="1">MPRKTTGCWTCRARKKKCDDGLPSCDACNLRAITCYGYGAKPAWMDGGDEEKDMLRTMKQRAKESYSQRRRARAMRSARQGSMSTMATSTSTASPGGMKSELEDSPATLTAVHSGSSGSRDPQQQQQQPDGRHMDIRPDDQSSPNDPHHHYHHNHYNNHHNPQNHHSHNGHGNGHGHGHPGPMEPHASYAAHPSYTSHPSHAAPPHTMSLHPPAQNPYDPRHFQDAPLPAIAPPYQRPRSRSPPNLPPPPLPPPPPPQESGRSGSDFPYSENDLALLMYYFDHVFPRLCPFFTYYAGDEGRGWLLSLFLRTKPLCAAAICISACDQAQFVLGPLSDMPEGTNHDLEMKHIAIVVDLRAHLAQLSQQTGASRMAVAVEALACVMHLILFELWIPRHGEVNDWVLHLDAAAALLSSVDSTMVNGGSISSDSPMSMSMSMSMSTPSDNNSASASAGGSSSTARDERSIETFFPVEFLSDCESSAFKFFLTQYTYCFVMSAVGHELTPQSVESIQRTHAIFHNGQSKIRDMFGLEDWVLTTMLDVAVLKAWKQRERSAGTLSLRELTRRADVLEACISQGLARMAATETAAGLSELTNPPSTVREGEPRPAQLTRDEKSHMVTSTYLNATLLFLHIVVSGFYPNLPEIRRSVLQTLNALEFMRANCDINIPSWPFCVAGCLALESEYPQIRALSPAPKKGHHPLVLTQWTLAIIERCWQMRAAQPNKMEETVDWVTAMNDLGTRLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP29</accession>
    <name>A0ABR3ZP29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001533</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF6">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="82" mass="9486" checksum="12DC75C8D0009608" modified="2025-10-08" version="1">MHIDLQRTGHFECSHPKGNKLHENTVWSMRGNFFSVPTDCPQRDERLGWTGDTQVFCNSANFLYKTAGMLGDWLKDIRAEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPC7</accession>
    <name>A0ABR3ZPC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000995</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="257"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="514"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="259"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="452"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="976"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1122"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="976"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1345" mass="149289" checksum="4851E57AA6CA9B25" modified="2025-10-08" version="1">MPVIPEEYEGSSDGDMDNFVNWDASAGAAEGMVDGHDVVCLPTDVEPIFPDQALDAHHLLVSPQLQQMNDREASLLFENPDADDFSFWALEHYEQSNNMLAGLGLSSQDITATAPITETDVAVEALLNSTASAMPVDQANDLFPAGLYGVPDEPCAHCKLGGYQCKTIQEGSYKGYCTSCVALRCECSFGLACGGPVPTDVSFPSNPWPVMGAHPDPIRHDEDMDAVTRLSPKASGVPATADVPELAAPSSPKGFAAAQPKLGARFSRESVRILKNWVSTHSRHPYPTEEEKESLQRLTGLNKTQISNWLANARRRGKIPTTRSTSPHVRNTYSGPNTVGAIDIPQPRRSGTPSPFDRRPQTFENIPLQRWANSPPENEPASVTDIARAITSSASAISSGLNSPLSLNFTDDGSGRSLFNGSSASSLGTSQSSGTGSFASAFSHASRNSFGSTFSSLGRGRRRRRRRSAPTHGVGSSGDREDKKMEKKLSRQAAKLAEATRSGPTPLIAPLKTYQCTFCTETFKTKHDWQRHEKSLHLSLERWVCTPQGATAINPETKQVCCVFCGEVEPDAEHIESHNFAACQERALGDRTFYRKDHLRQHLKLVHSVKFMSWSMEQWKVATPEIRSRCGFCGIVMDTWTFRVDHLAEHFKTGRTMADWKGDWGFEKPVLEMVENSIPPYLIHDERNSPLPFSATSQSPGSPRNAYELFRGELAYWIQHQQDKLNTVTDQEMRVEACRIVYAAEISISSSRDNPSWLRDLVMDDENCAQHARMSPIRTQAESRMAAMRINGQESVFDLCPLETALHEFVRDRSQLGLTPMDSELQVVACDLIRKMEIQLIEGPGESISTRITTEKKIAEFWLRLIKGSTRWLAAFRKRAHLPRSDAIADEARRPVDDPSNIDATIHNYTRLEAELADYVRLQREAGEITPDDTTLQRQARLIIYDHDDGWNQTAADDPQWLEAFKNRHIVKAFPTTTLRRSTSTSNSSGSVHSSSQSGRPQHSPNLLVPSPFFLNDTNCYRRLARELTRFANMVMSPNNPNCHVPTDDELQHQARWILYDDDDPWNQTAADNAEWLMRFKRDVGILPSEDGPGLPIENTAWNVSQGGTGFAPPYCFPKTPLAPFPSSAEEGAGDAGSGSSHASAMQLQNPPTMHGIEFELTSETANKYLQSFMTRYAKPATVFCSRELENGLTDYVRTTVVQNGQSFPDDNALRAKACEILGCTAQHGTPADDKELLGKFKDMVRGMLTIDQTQQTVPELPTMPEVFDMNIGDIKTVAITNNNINNNIQNINSMPLDMSGMNSMNDMNMNVDLNLDSVTQEDMDNLFQDMNFQFDDGVDFINGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPG9</accession>
    <name>A0ABR3ZPG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA-splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">spp2</name>
        <name evidence="7" type="ORF">Sste5346_001008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in spliceosome maturation and the first step of pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the SPP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045166">
        <property type="entry name" value="Spp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026822">
        <property type="entry name" value="Spp2/MOS2_G-patch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818">
        <property type="entry name" value="G PATCH AND KOW-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818:SF2">
        <property type="entry name" value="G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12656">
        <property type="entry name" value="G-patch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Spp2/MOS2 G-patch" evidence="6">
        <location>
            <begin position="240"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="370" mass="41637" checksum="F0E0CE8AE6027A39" modified="2025-10-08" version="1">MSTPDRPEASRIAIKFGGSSSSSSKKPNRPPPPSSSLGKRQRPSHGLGGGSDSDSEEDSPKHGRHERITAFGDNGAELARSARDEREERRPAKRGPLTIERQPNRDWKTEARSRNQRGGRAPESQIKNNSQKEVEPADQDKPIKWGLTITKKASPAESEQDSTSNNNERTNSRADTPTKEDSRATPEAPVGHVAHTEKEAIKALLGETIDDKTKTRRVIERAANTVSEDDVFSRDFDDAPDVSTLEEYEAMPVEEFGAALLRGMGWDGKDRGPKVKQVVRRPNQMGLGAKELKGAEDLGGWNHKSGTSGSSSSHRKERPPRLHEYRREEDKRREKREERYRDSYKAERDRERDGHRSHHSSSRHRSRHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQN0</accession>
    <name>A0ABR3ZQN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045477741" description="DUF8021 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="3">
        <location>
            <begin position="163"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="320" mass="35507" checksum="C7E72EC54CF2C659" modified="2025-10-08" version="1">MYSSLLTWFALWAASAVVASPIANTSDCTRDFLKAATDTYLAAQTQGTPDTLLGKYATGNITYTEDAIVRNLRTGVLSSPLAIVHNFSLLDTTQCATFTELIVTDPRHPRVIGTQMRFVGKWLAKIETLVTKNGDWAFNATGTLHYAEEESKAGKWGPLQDAERNTREVIQSAADAYLDLFNNKSVVVPWGTPCDRLEGSWYTGNGSQSDSCNVGVPSGVVITNRRYIIDELVGGVDAFVTFGSRPDSHMFRVAAGVIRQVHTLTVMRNVTETTELLRPANDDTPWSQRSKRLSTGTRTSTNDDTPWSKRTMRWQPRKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQW1</accession>
    <name>A0ABR3ZQW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="51017" checksum="F08D7B6C3C3909EB" modified="2025-10-08" version="1">MSTAITMAPSPAPHDRPSFGNGSSSANGTSSSSGNTAASNAELSAAAVAAVSSSPTAHRTSSTGAATGAPLQRMGSRSPRGAAQSSANKSSPPSITRSVAPPPKIVVKKEPGSPEPTPRRRPGKLDLSKGGATSTTPGTGRPLTARDGLGIQEVGLACLSPGFVTHDPAMKEQLQRSMTVREQQRHIIEARLQQQSAKGDGTMDTSNKDSANPFAAKTPGMSRRNKAPPGLSIVAPSHETFAHERVIQSAPLGQTFTGMHNPHPLTRHITNQPSKLSNTSHIHHVPANQTSNRLPPIADVFGQGLSGHPESNGHATYLQQTGRAPLTSPSHPPPMSHPPLPPHAQQRQQEQSHQQHQQQQPPLSGRPREYRSAEEAQAELAGGRPELLPKLVHYGGHQPPTPPSPQHGYASASSRPAEGARSTSRRRTRAEYEDGSPPLGAGRPAQRRGPFGEGRDSPETQRAKRDEFLKLCERAWDLFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQX9</accession>
    <name>A0ABR3ZQX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MATE efflux family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001036</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="75338" checksum="55411E3909570C30" modified="2025-10-08" version="1">MAPSSRPIPTGSPGTGNHRESIAGLASSFAASLADPSPLAQEVLARDIAELTPSEIEAENRAAASAPASYHSAGIVPYADGNQDDIDTDTDLDGPGSNGPYLYRRPSAIAYGNTRPILGVAASSGPALSKVEKLKSREAERSLLRDNHLLPPKHATASDSGHAGSSSAGGATDGREPGFFTRVYKSVFSTRRPKDTAEEERRLQGDGVDTVPTPGVPDERTALLTPTPPAPESDGSEVEPRLDEQWNAAVAAGQIHTTWQREAKTIAVYSRSLIITFMLQYSINITGVFAVGHIGKAELGAVSLAAMTASITFYAPCQGLATCLDTLCSQAYGSGHKFLVGLQLQRMCCFLLLLCIPLATVWVFSEDILKGLVPEREIAALAGLYLRILVISMPASAVFECSKRYMQAQGLFTANTYVLLIAAPLNIFLNWLFVWHLELGYIGAPISAVITQWLMPLLLFLYVYFIDGSQCWGGFTWRIFSNWGPMIKLALPGMIMVEAEFFAFEILTLGAGRFGSTTLAAQSILVTLTSTTYQLPFPMSVAASTRIANLIGAKLPNAAKTCANVATVAGVGLGVFNCLWVLIFRYQIPRLFTSDTDVIAIVAHTTPVVAFLQIFDGTACVASSLLRGVGRQEIGSYANLAAYYIVALPISFFTAFGLGWGLPGLWAGVGIGLLLVTIAEYAYLYSYNWNRAVEEAEVRNLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRG0</accession>
    <name>A0ABR3ZRG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mhck ef2 kinase domain family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04515">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056861">
        <property type="entry name" value="HMCN1-like_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052969">
        <property type="entry name" value="Thr-specific_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763:SF4">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25106">
        <property type="entry name" value="VWA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00811">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VWFA" evidence="8">
        <location>
            <begin position="243"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-type protein kinase" evidence="9">
        <location>
            <begin position="649"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="894"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1019" mass="112940" checksum="1086BB93D2DBABCA" modified="2025-10-08" version="1">MTPPTQPPEAPTDLPPPPPYEPNDPANDEHHNAPPPAFASRNSTLVAPRGPPAPIEFPTADRPDRPAPSNQPVPKTEYGYPDETAILKQRDAEQNAPTGTHYCSTTTRDNAFTNPYASPAPLPGSTSPVKGGPFSPSQLSQIEPQQDIPSSFNRRSFFRSSVGNLRETLSGSRQSRPRAAPAERTASQMEQFARRLEMQNRSGPSAAEAEKRVMQLRSDAAQASFRAGPRVSTGIFKASCSTDLLFLIDATGSMLSYIEAAKTQVRTIVSDINRTFFNEADVRVAVVAYRDHNDRKPLEFLDFTNDVSEVFKFLNSLIATGGDDVAEDVLGGLDQALKASWKHQTRCIMHIADAPAHGNNLHEMGRHSDHYYGVGTEPHGLQYQTVIKEMMNNKINYIFFRVHTNTDKMSYMFMMIYGMHTTACKLHQENKYALTSAQWLKDQTARNRAEMLRASAKEYMEKKMEDEGGLHFEEVQLGISYSSLRHLVVNSVAASSSRTAVRLSASLSASGGRRNRSSITKSKLGHKTATLSNLDEDEQVDVFEEAREWQSELEIRAVRDNFDSVTLADTIVEADEEEEEEEERPGASAKSKDRNIEFDTGEPQWNKKGWLDQTMHVKAFSPDVIDIAPPTSAVAHTLASSAAVSVPGAGTSILDRMMQSDDNIRISTNELVIHRRTKPFAQGALRLASYARTQESTNPLVVKTFKANGKRLADLAEDMRMQALCKAFALEFNSLVASEEHSLDFIVVTCLQPISSSSEDDECMSLEPMLQNGRYVKYNNNCGSVNDDNNSEVSKAAQAFSHFTFERSQGELLVADLQGIDNVLTDPAIHTRDPHRFVLTDTNLGVDGFKLFFSTHKCNHVCMKLDLKSQAEMFIRNDFVYRTDWPAITYHQAAGTGAGSSTSGSSSKRSKNGPETLVCCSNKLCSKIVRVATARKTAPSFYWCDKCWPQLRLSTVKRVCATPDAYHEFEVSKFFFESQGQLMPQTCADHGGVPSLPVAFEPKSKGLNFFKRRRPGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS01</accession>
    <name>A0ABR3ZS01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEN34</name>
        <name evidence="9" type="ORF">Sste5346_001245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059049">
        <property type="entry name" value="TSEN34_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26577">
        <property type="entry name" value="TSEN34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TSEN34 N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="7">
        <location>
            <begin position="334"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="424" mass="46248" checksum="F53B0B1CE98C6C2D" modified="2025-10-08" version="1">MASVARPVGRHSHEMEGTKENVDGKIRIAKIGSRFLVFEVADVARLRRQHNICAVLVGITPQAPNQTVFSSLPLELTADEVRWLVYERQAAYVADDWQAHLSSLAQPAARHAYMDNVLRQRQAAQVVADEVTAERERRGAEVRAAQAAKRAGKKAKNAASKNGGGSKPEEPVDVKKEAKPEVPVEAEKETKATVIEPIETVAADIPHKIVVATATDRANDHADLEPLLRPPPRTEGVMQQEDDFIFGGLVELERMKAERARRGTSPAPEKMETAPPAKKEEKKETPKNLVRITPTTSAGLFVDEKEDQDANALIPPRSICPASASAFASAALRAHLADRGYYTTPGLRFGGQLSVYPGDPFRYHAHFVANSYGWDEPIRMLDVVGTGRLATGVKKGLLIGGAKPAEDDTENAVVRTFTLEWAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS56</accession>
    <name>A0ABR3ZS56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000899</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="431" mass="47065" checksum="2DCCC9E39380DC85" modified="2025-10-08" version="1">MAPSATTYGTSPASEAAAAQHKNEQDVDLTGQALEHKMAEIAKSKNGSSTPSTKAELDASKLIYELTTSPRPVPASIEAACAGTETICTDHMVTVAWDAETGWATPELRPYGPLSLMPTASVLHYATECFEGLKVYRGADDKLRLFRPDCNAQRMLTSAVRISLPAFPPVELEKLIVALMAVDGPKWLPRGGGPDEYLYLRPTMIGTQPQLGVQAPRSALLYITASYMPRLDVVKGGMRLHTSPEDMVRAWVGGFGYAKVGANYGPSLQATIEARARGFHQILWLYGPEGYCTEAGASNFFVVLKDKETGQTQLVTAPLDDRLILDGVTRRSIVQLARERLAGEVEVVERRYTIAELQDAHKEGRIVESFAAGTAYFVAPVSLVHHRGEDIPIPMATETGGKYTKLVKSWISNIMYGQESHPWGVVIEERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSF2</accession>
    <name>A0ABR3ZSF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">FAD-dependent urate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ADP1</name>
        <name evidence="12" type="ORF">Sste5346_000247</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045599412" evidence="10">
        <location>
            <begin position="25"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="859"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="894"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="936"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="972"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1002"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1027"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1062"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="371"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="632"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="672"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="672"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1114" mass="121069" checksum="75594D23C9210C3C" modified="2025-10-08" version="1">MAPLRFRALAVGAAAALMANSVVASAYNTSFTSIDAMRAEMALLTRDSDCPPCFNCLLPSFNCGQFAECNNYDGTCKCPPGWAGIDCLEPLCGSLAGGKDRPMRGDAPACECEEGWTGINCNVCTDNLACDALMETGDGGVCYQMGDVVKNNYQMCDVTNKQILSILNGKIPQVTFTCDRNTSECDFQFFVDQRESFFCHLRDCESDAQFDETTNKTQYHCKNIDCSCVADRMLCGEDGSIDLSDFLKESIKGPASFECNQAEGGSNNCLFDEPNMNDLISSVFGDPSIYLTCRSGECLYNTEVPGYKRPVSRINTPLIAAVIAGASLFLVAAILLTWYLSRRSFNYGPVQFDDSDDESVKLMADHRPASLHFENVSYSLNGKNILNNIQGLARPGEVMAIMGASGAGKTTFLDILARKNKRGEVSGDFFVNGEKVSNQDFKNVVGFVDQEDTMLPTLTVHETILNSALLRLPRDMSRSAKEQRVYDVEKQLGIHHIRDSLIGSEEGHGRGISGGEKRRVGIACELVTSPSILFLDEPTSGLDAYNAYNVIECLVTLAKTYNRTVIFTIHQPRSNITALFDRLVLLAQGHTVYSGPFARCQDYFDQIGYSCPPGFNIADYLVDLTMHAGSAPSYEDEPSTGLATGSDAASDRPSSTRAVKSIASVSAASTMADEASAGNAGEASSSTLRFKGKRRNSVRARQERELFTRRKNTIETTASSDAGDHEIGAYRLHRQTPGSVAPQILDDIDNPPPSALGGTDLDILITAFAESSVAQSTHDEINQAVVDAHNANGNNSVASPVDDDADVDAAANVSANGYSPVGPNIHLSVVGKGYARVGYYGQFIILSQRTWKNLYRNPLLMLTHYAISILLGVLSGFLFYGLTSDIPGFQNRLGLFFFVLALFGFSTLTSLNVFASERLLFTRERANGYYSPVTYFAAKVLFDILPLRILPPVLMGAIIYPMTGLVPDLQHFVVFILVLILFNLAASGICLFIGIVCKDGSVANLIGSLVMLFSLLFAGLLLNHDKIPAAAVWLQYLSIFHYAFEALIVNEVSMLTLVDHKYGLDITVPGSAILSSFGFNNIALWQDVASLGVFAVVFIILAYGAMHVLLVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT19</accession>
    <name>A0ABR3ZT19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase catalytic subunit A</fullName>
            <ecNumber evidence="2">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">VMA1</name>
        <name evidence="15" type="ORF">Sste5346_000480</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Vacuole membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007868">
        <property type="entry name" value="Hom_end_hint"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007869">
        <property type="entry name" value="Homing_endonuc_PI-Sce"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05204">
        <property type="entry name" value="Hom_end"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05203">
        <property type="entry name" value="Hom_end_hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0651">Protein splicing</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="14">
        <location>
            <begin position="464"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1903195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1095" mass="120306" checksum="BA2DE0D0A618787F" modified="2025-10-08" version="1">MEHTGKIYSVSGPVVVAEEMEGVAMYELVKVGHDNLVGEVIRISGDRATIQVYEETAGVQVGDPVLRTGKPLSVELGPGLLNNIYDGIQRPLASIADVSKSIYIPRGIATHALDREKKWEFRPTMKVGDHIAGGDVWGIVHENSFITEHKIMLPPRARGTIKRIVEAGEYTVDEKILDVEFDGKVTGYGMMQTWPVRAPRPTTEKLSASQPFLVGQRVLDALFPSVQGGTVAIPGAFGCGKTVISQSVSKFSNSDVIVYVGCFAAGTPVMMSNGTIQPVETIDLGDHVMGKDGNPRMVMGLPRGTETMYKVSMKTQHRNENASLASFVCNASHLLVVVTPQHIRKTTHVVRGKMMTSVCWFDWHTAQAEDGRPVRLVKLFTKSWDHDAHGGEAAADAKAAAFQSELPAGDFEWSIETRDVSLLGIHVRKATQQLINPVLFQAGHLSQVLERHGYESGAPEMAYLLGFWVGDGYYDRAAFAVDARDTAIKGRMQEYGSLFNLTMDTREYKKDMYSNQADAKTNPTDDSPTKEARKILGDLQVNATLNPGETSPTVKKGFTGIGDETIFLRSSGTLAGAGKRKPLNTDNVFWDVANAMGVRGPDEQHAKVIPDVLMCEPFEVREQFLAGLIDSEGHVKHSPPSATIKTIYTAICDGVIKIARSLGVRVSVSAEAATVVRGVSHKKTYAVFLSDPENTGVLASILSRCALERKKLPAPAAVNRKGQAMYFDLEKQAPAKYYGVTLADNTDHQFLLGNMTLVHNCGERGNEMAEVLKDFPELSIDVDGRKEPIMKRTTLIANTSNMPVAAREASIYTGITVAEYFRDQGLNVAMMADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGRVNSLGSPEREGSVSIVGAVSPPGGDFSDPVTASTLGIVQVFWGLDKKLAQRKHFPSVNTSLSYSKYTNVLDRWYEKDHPDFPRLRERIRQLLSDSEELDQVVQLVGKSALSDPDKITLDMATLIKEDFLQQNGYSDYDQFCPIWKTEWMMKLMVGFHDEAQKAIAQGQTWAKVREATQELQGQLRSLKFEVPGDGEDVITKKYEDIQAAMLDKFASVVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTH4</accession>
    <name>A0ABR3ZTH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="11"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="299" mass="32829" checksum="11CC48A9AD3110F3" modified="2025-10-08" version="1">MAKPVVPPGAWDTHIHVFDPETFPYANPRPYTPRAAAVAEYPTAVTGCTNVVVVHASMQGTSPAPLIDTLKKSTDSLRLRGLATIDVDNITDAELDALHAAGVRGARMHEMAWGHGAQNGADAITVKIERLAARLARLGWVVGIFCPLPAWAAMADMIRNRLDPRIKLVADHFGSAFPGDASTPEFATFIDLVREKRLFVKISGFERLYDGNPDGIESLTPAAKAIIAAGPDQIVFGSDWPHTQLGVSRKGKTVEQRINEVEGFRTVDNAGHIAKIREWIPDEETWHKFWVTNPQRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUN4</accession>
    <name>A0ABR3ZUN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF6">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="603" mass="64300" checksum="8B108B6FCD039C2E" modified="2025-10-08" version="1">MSRSLRIAAAQMGSTHYADPREKTIGRMLALLDGAVAKGAQVVMFPETAFGTFFPRHLISDPVELDSFFEHGDIITQPQTKPLFDRAREHKAHICVGYAEKTDAGEAFNACVFYDGQSGALLSKYRKIHLPGDVEPFADPDALNQLEKRYFRPGDLGFKAFRVPGLVDSAEAAIQGDPIFGMMICNDRRWAESWRVLGLQGVEVVLCGYNTPGFAPHLYGTNGTPAADDYAASRTKALFHHHLVMQAHSYTNSCFSVCAARAGLDDGKYELIGGSCIVGPDGDILAQASTEEDEIVVADINLAECKAGKTRTFDFQRHRRIEHYGLITQQTGVVEPPRLGSNGIVSTAAAPPPRKIRILLVNPNNTASMTAECVALAAPTLPPDVELTGFTAPRPAPSAIESSFDNVMSAAAAARAVLPIAATHDAVLVACYSDHALIRMLREELTGQPVVGIMEASLAVARTLGGRFGLIATSDRSRVTHEDTIHNMGLSSICAGVASCKLGVLDLHADDAEAQERVNKSIFTAAQSLVAKGAEVLTLGCAGMTPLKLAVEAAVGPDVTVIDGVLAGVQHLSGIVRVGSRTAKIGVYKSSSATRKARGQDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZWK3</accession>
    <name>A0ABR3ZWK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046894647" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="27128" checksum="1BBD03F50A941F5A" modified="2025-10-08" version="1">MARRRALVFAVALTSMATLASATSSTQVAFTGCLGVCVNHNGCGATNTNCVCSESAKSAFLNNVVSCVANFCLLSNGDNSAATANSVIDAIDSQFLEVVSDVCAADKQSVPASKISAALSSASSLVSEVLGATPTGTTTVTTHATTTVYRSTQTAQAKTTKTVPKAGATSSTSSSTTSTSEETTSEAPATSTTAAAETTTADKKDTTTSTATTKTAATTTTEAPAKDTTDSSPFTNTREDSAAARPFGPAPWTVAAAVAVPLFLSMGLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGB9</accession>
    <name>A0ABR3YGB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000131">
        <property type="protein sequence ID" value="KAL1887282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF3">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="368" mass="39879" checksum="615DCEB2F0D6E90F" modified="2025-10-08" version="1">MAEPVSLEWFGASTFRLKANGIVIFLDAWIERPSSIPTYLKIEDVVHCDYIFISHAHFDHLPGADRLAKATGATIIANGEAIAVMRDAGVPESQLLAVAGGERIPLFTKEQRNEAVRKAGTPGPSGAPGPLASPGPTGPGGPPGPPHGPPGPPTPDPGNAKITVHAWPALHCLGVSADHTKFPEFIDTATRYEGSASHECTLDLTRGLTYGLGNLLKLPHLPPQIPQAARPFFEYMKDRDSHRYSFFDGGQMLFNFLLGEKTLLWSGHLGAYEGIMRDLEPKPDVAILGIAGRANLNGRPFDGSAAEFAVKEIKWLGEPAKVIWCLHDQAPLSPKWIDTKAATELVQKETKTRIVDLEHDVLYNIDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHE7</accession>
    <name>A0ABR3YHE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="180" mass="18750" checksum="C55A748A302CEB64" modified="2025-10-08" version="1">MAAIQEHSVQWHAGEIAMHRLLNGPHYAEPNPTSAGLSQAHASRVAASPLVAFGALDRKGRPWTTVLGGSPQFAQAVAPSVLGVRSVVDLDYDPVVDALFGSDTKSCSTKGDGELLRPGPEHGPVMAGLSINLMTRDRVKLAGRMLAGAASTRPDESAQGDQVARGRTGEVLLAASPGWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YID7</accession>
    <name>A0ABR3YID7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UFD4_1</name>
        <name evidence="6" type="ORF">Sste5346_010023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="E3 ubiquitin-protein ligase TRIP12-like TPR repeats" evidence="5">
        <location>
            <begin position="150"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="674"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="692"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="767" mass="83145" checksum="5F8523292C712C49" modified="2025-10-08" version="1">MDTAMSGADDPSSTTGDSTDKPAEFEKGGSQNGGHENGDGDGSDDSDGGGDEVDEDDEDDEDAEDNDNENNDEDEDEDDDDDDDDNDDEDDDGEDDDGEDDDDEDDDDGHRYSESGLSDPFHAGFAGSHRGSGLPAALSMLGGMLSMSGMGGRLREILNNLRRKEDPSMQLIALQDLSEILLVSNEDNLIGSFSPDPYVRELVALMQPNEITGEENPDMMLLACRCLANLMEAIPASAANVVFGGAVPVLCQKLLEISFIDLAEQALSTLEKISVEYPSRIVQEGGLTACLSYLEFFATSTQRTAVTTAANCCRNIPVDSFPVVRDVMPILLNVLNSNDQRVVEQAALCVSRIVESFKHYPLKLEELVGVDLLKAILRLLLPGSTNHFIGPNLHTQFLRVLAITANDSPRLAAELFKMSVVETLYQNLTGVSPPVGVDDIAAKLDSALIMQALIHRPREQIIETLNVVCNLLPTEVAAAPVDSVALDIPGTVARDGDIIETNEPSSMSEMSVLNEKRLEFLSECQEEVRRFTLILLPTLTDAYSSTVNLDVRTRVLAAQIKMLSNFDRDIILEALKAVPFASFLASILSQQDHPALVGYALQATELLMSRLGDVYRYQLYREGVIGEIEKIAAIEDDGHPSTLPAHSDQASEIPGFATHETGNRPTLEIGIYEQRGSLNPSPSRGHKKQSLRGRDPDDADDGIDRLSSDAGLELENKNGHGDDIGDEEVESRGGGDNTVGGLRDSDDRDEDPGDEVPGSLERPLEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIS3</accession>
    <name>A0ABR3YIS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF15">
        <property type="entry name" value="LIPID TRANSPORTER ATNI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="325"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="491"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="562"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="609" mass="65123" checksum="F5B9CA9B0D70F4AD" modified="2025-10-08" version="1">MAVSFGPFPTIGDSRFTSEWGGAAFAGIFGLLTILHLVQGCYYRLWKVATAAVAGGLAASAGYILQAAGSRQRGDPSDTDNVQPYLLATAFILLQIAPLCITLVPYATLNRLARTRFVPAHDSLPDDMRRPWPSNGRWIAAWPVWVLLVIAAAAQAAAVAFLVYCGLTTSSAYDIPRALLVAAGLVWAGGLAAQGVAVLILLAAVTHAYATLPPARPGGQQERDEAGTVRPSLPPRRRRKIVWLLMTTYGVLALLVMRIVYRTVEAVMAAEGKSTASIGVDAKTAASSASRSTLYALVLDGLPTALALLLLCACHAGWALPATEARHSSSQGGGRSGGSNTPTSGGDDDADERMDALHDLESPVEGRGYFGQPSPAEAAEGGQELSTEQVLLQQRAALQRHYRQRQRQQHRQSQFRPRHPPPPVVEALARFSLSASLSVSLPRESFVGGERPARIPAPGEPDEAAGGAPQRLLARLSMDNFILFRFLNTPSRSTSARSGGARTIPQSVRSAISRATSQSHGGGGGSQSRSQSHGTGTNYGDDPFAGFDDVAQAGLQTEEAPQQEHQEHQDREPQEHQNQERENALFHDSDSRRTCDSPDEKEKLGPEWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIX8</accession>
    <name>A0ABR3YIX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20028" checksum="6E986E263F6A7D21" modified="2025-10-08" version="1">MFGAFPLAGKIVAVTGGASGIGLAFCKLALSSNARVIIADLKLNRDTEALVADNNKASFYKCDVRNWKELEDLVPFSESKFGNVPDVYAANAGIAESNSTGFWNDAEEDKYAALEVNLGHPIKLSRIAIRALSSRGKKGVVVITSSIAGMHGHFTTPLYSASKHGTIGLIKSMALAETEANVKVVGICPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK46</accession>
    <name>A0ABR3YK46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050197">
        <property type="entry name" value="Aldolase_class_II_sugar_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22789:SF0">
        <property type="entry name" value="3-OXO-TETRONATE 4-PHOSPHATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22789">
        <property type="entry name" value="FUCULOSE PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="272" mass="29724" checksum="AC0D809D7AFC747D" modified="2025-10-08" version="1">MASSIANIDETLLRTYIHGCHIMHHHQVVDAYGHLSIRISPTIFLMCRYMAPALVSSRDDLVLYSVDTGEALDSNAPRGFSERYIHSEVYKAYPGVQAVIHSHSLDVVPFSLVPSRPLKACIHMAGFLGTAVPVWDATASYYQQHPDAERSMLVNNTEMGASLATALSTADCYGLPQHAVALMRGHGYVCTGESIEMVVAKAIYTAHNARVQTTVNCLVGASSTTSSNTPDILYFDEREATDTGRTTIQGAAKPWPLWVAEVTKDSLYTMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKT9</accession>
    <name>A0ABR3YKT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="497" mass="56503" checksum="E05EC5B75496580D" modified="2025-10-08" version="1">MSSTHTTSQPTSKDNLSHNVSAYEFDYMMASVHPQHHKLPMFGDALPIGGPTVEFGPKLSGHHATRNGHDHFSISSLEIEEDRKERLGLPGKKRIRAKFVKRQKREQREHMPPGFCLIELSAKRFLKIGFDLNRKNCGASHIDYQQACREVRRAISKAIRDGFLPPLTDGIAQDVTDTSNPDTHSPVAWAKHMYAFCNYEVARLMHPFLGDDKFRSFFRIFRCCNRITLRLFRNKEVQRAYEARQYQHGRYMYELQQMEHQQYSDGQPQQDHILSASALEFVPTSTPNSMPGIKKYNMQKEVNQQVPATVTPPASKPTTKYWPPVILNGSSKPHDPVVETDDVKEVPPEEEKPDKPEPDKLELDKLEPAEPEPESPPSSSLSSDGTAYATDDSEDNHWESQPITPASSTGSLPMKISIIIVTPPPDDDDNSTKCENWAEEVRNCVDPRYLMVPGQQPFVAEEVQPAHSVKFAPLPRYNDDRPEFDSWADEVEDELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLD7</accession>
    <name>A0ABR3YLD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="299" mass="33343" checksum="64AE3E51B8D86B0A" modified="2025-10-08" version="1">MHSVFTLNTGAKIPALGFGTWNDKDSQEEAVLTALKEGYRHIDTAAIYGTEPAVGKAIKRSGVPREELFITTKLWRADMKPEDVAPALDKSLEKLQLEYVDLYLMHWPAAQLPGSKTQTSEVDFVDTYHAMEKLVASGKTKAIGVCNFSHAELDRLLASTAVVPAVHQMEMHPWLQQTAFAIYNRSLGITITQYSPFGNQNDTYGAHGERLLDDPTLKRIGAKYDKTSAQTALAWGIGHGHAVIPKSKTAERIKQNLGGDFHLHPEDIQEIDRLDRKKRFNDDSDAGYSYFQDLDGKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX8</accession>
    <name>A0ABR3YLX8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SsDNA-binding protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RIM1</name>
        <name evidence="3" type="ORF">Sste5346_008927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302:SF0">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="139" mass="15129" checksum="55782D92A5BAF3BD" modified="2025-10-08" version="1">MSFVMRRGLGLTSTLSSSARAFSTTPARRVARITIVGHLGDTPELQATSTGHEVLKYVVASSSGPRDNRQTSWFRVSSFLPEGPQRELLRGLPKGTLVYVEGDATMGTYQDAEGKTKSSLNIMQRSIEVLKRPAQTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN84</accession>
    <name>A0ABR3YN84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="146"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="306" mass="33398" checksum="815132B680ADBE35" modified="2025-10-08" version="1">MTSYCCTCAAPLSAGIPISLTAPATSMPDAKAATASPQHRMLPCCDRFKNARFATYCPYCQIATAPPPSSSTSKQSKAAEAASAPSKDLLPPGLKAPPPYRRFGVVATMSADQPSDEAPPPYAPSTAAQTQTPTETSSSEKGVPILHYLDHDRDSIASLSLRYNVPADLLRQANRLTADHLLQARRVIQIPSLSGTTVASLSPQPVEREAEARRKAAIRRFMVACKVSDYDLAVLYLEQTGWRQTTDTDNNELEYDLRAAVEAYQADEQWEKTHPVEAAKQKAERQKKHKNSCSRVAGGFFSRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNA7</accession>
    <name>A0ABR3YNA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF2">
        <property type="entry name" value="DUF3533 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="2">
        <location>
            <begin position="47"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="442" mass="49060" checksum="70B787E4177FADF2" modified="2025-10-08" version="1">MPLADMEANKEERLEAAQPVEIDRKRLLHPYWHGRRKAFIIPKIMMGLIIIIAFLLIMSNFFGSASEQAKRVKALKVLVVDYDDGVIGTSFANAYNQLKADSFPTVEFRSASQFPTTESVHDAVCRGGYWAGAYVPSGASSRLSAALKGGAAAEDYSESPAFTYIYNQARYPTVADGVLLGGLTEWVSAARAAYYQTGNGTTLATINQTDAASVAAYLDPITSAADIIMPTTQGARVYYDTAYMVPPCLAPFFLILAMNGISGLHDVFARAYVRDVAVLRFVIGKIYTFLASLAFAGYLWGFRESWQVGGREFVLTWMVMWLDLEVNWVIMESLVASFIPLAFVSVFVVSWVMVNVASAVFPFELSAGWYRWGYCLPAHNTYVTLVYVWSRCASPLRYSLPIMFSWWVVGHVVAWFSILKRCRDAEKQLKASLESRGGDTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP77</accession>
    <name>A0ABR3YP77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enolase-phosphatase E1</fullName>
            <ecNumber evidence="7">3.1.3.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">UTR4</name>
        <name evidence="8" type="ORF">Sste5346_008647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.77" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03117">
        <property type="entry name" value="Salvage_MtnC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027511">
        <property type="entry name" value="ENOPH1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371:SF1">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01133">
        <property type="entry name" value="C1.5.4:_Enolase-phosphatase_Li"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="249" mass="26530" checksum="EECD886F610541B3" modified="2025-10-08" version="1">MAAAAAKKAIQVVLLDIEGTVCPISFVKDVLYPYSLSALPETLASKWDSPSFAPYRDAFPAEYRASPEALTAHVHDLVARDVKASYLKGLQGLLWKEGYENGTIKAPLFADVLPAFTAWQIAGITLMIYSSGSVAAQKLLFRYTGVVGEATNASTPGKDVTPLLSDYFDTVNAGPKTAAASYSTILAAHAKEFPNASSWLFLSDNVLEVAAAKEAGLQSYVVQRPGNAPLAATVADEHKVITTFEGLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPP8</accession>
    <name>A0ABR3YPP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_008292</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="64"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="541" mass="58856" checksum="80E0D9B68D039F70" modified="2025-10-08" version="1">MQEKVSSDAIERTTSSSGSGEGDVVSATGAAAAANPSSLVHIDVNAPRKKYFFGAQGKSLVRAVSAAGTVGFLLFGYDQGVLGGINTSEDFLNQFNDPSDTLLGTINAIYEIGCFAGAICVFIVGERLGRRNCLYVGAALMAIGAILQASSFGVAQIIVGRVVCGWGNGFNTATTPLWVSELSPAKSRGRLVAAEGTLIAFGIVIASYFNIGMYFASGPVVWRAPIAAQLLFIIVQVALTVILPESPRWLTKHGRHQEAVDILAQLHGRDVALDDPAVLQTKGAIDEALAMERAGGPWKLSEAFQSGPLKIRRRYLLAIGLQAMQQLSGINLLVYYFPHILTTNLGMSTETALQLAAGLSVTYFVFSLIPLFWLDRMSRRKPLIGGAFVCALCFLIAGILQSNPTDARVKASLAFFFLYEAIFAIGWLAIPWLYPAEIMPLRHRTHSAAIATAADWIFNYMIVQITPIMITNISWRSYLIFFVLNLVFAVTIYLFFPETSGRSLEEMDSMFIGDGDHVFMVNAKGQLRPAFRSQYNKDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQI4</accession>
    <name>A0ABR3YQI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106617" evidence="3">
        <location>
            <begin position="30"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="584" mass="60767" checksum="486DB706C6E0FC59" modified="2025-10-08" version="1">MARQHHKRWWPAGLWLPLLLTTAAGPAWAVGGIDTDMTVASRIPGVTDTGAKVTDFFRRLAAPLAAPLAAVADEPNIMAANTDEQTQQMLQSIARREDVRRERENVAPAVAARKPQPLQTPPPSLKSRQNADDGQIQALSAQIQSISLVASSISQASRQVSQTSQQLAQSVTQLSQSTDRLSQSINSLQNSAQQAQQSAQSAQDAARQASQSASQAISSAISSAQSSASAVVASNIASITSSASAIIAAASASAAQLARVAASQVQSAQADATIARADAATQVQQAQGTAVSVTQAALAIVGAFVGSSLLTILAFYLVLRYKTNRKRRRTRLIATRGDNGYPKQGDDDDTDNRGTYGYPIDLKDPPRKSMTGGGGDSDGFNEKRPEAAHLRGTSAVAPTNKNGGGDLGAGFGFGGAFGSGSGSSISMVGPLPASNNNGAFGPRKGSVNNGRSSFSLFPKTPTSDRDNETMPSTQAQQVVSPSIYATGTSAMTNTLSRANTTTNNPTRAPPSLQQWLREGTVSPFGTLKRTSVTDNTVAAATSPDRKQQQLRNMMKRSVGVGGVNAGGGGSRVMQPGRSLPLRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRJ0</accession>
    <name>A0ABR3YRJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008217</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.290">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023149">
        <property type="entry name" value="Trans_acon_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="57"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="290" mass="31971" checksum="052FECA65E7F6BD8" modified="2025-10-08" version="1">MSASKDGNKDGKDWSADQYLKFNDERTRAVHDLVHRVPLPGGRFPLSDKKGDAPLRIIDLGCGPGNSTAVLAERFPGAQLSGVDSSPNMIAKAKATLPNIDFGLADLRTYAPEPGANLLLANAVFQWLSLPERLPTILRLFETLPSGGVFAYQMPDNKAERTHQAIREVARHEAPGTSASDPWVATLSQLHDRDPIETPEQIYDALIPHSASVDVWHAVYNHVLAGGPRDIVEWMRGTGLQPWVNALPDEATKQAFLAAYERRLGELYDRRVDGSVIIHYPRLFVVAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS11</accession>
    <name>A0ABR3YS11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">H/ACA snoRNP pseudouridylase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GAR1_3</name>
        <name evidence="3" type="ORF">Sste5346_008052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045989413" evidence="1">
        <location>
            <begin position="20"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="2">
        <location>
            <begin position="154"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="27512" checksum="B2D4BDAE2EC9D32E" modified="2025-10-08" version="1">MRLSTTLTGLLGLLPTALAACTREALLASAEIYIAAQRTGKTDGLKLASNFTYRENNKVIDISKGVLGSTALVLDTNRSTADTVACASYTMLISSGGAKPYILATQLRHDDGDPSTITMIDTIAATTGSLFFNAKKTLGYIQAESWAPLATADQPSRDLLKKVGDAYLDMWTDKNAADTIPWGTDCERVEGSSLTKPCGASLPHGGSSQPNAMRRYVIDEVIGSVDVLCAFNSLGNYPDSHEIRLEGGKVKYVHTITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSQ5</accession>
    <name>A0ABR3YSQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007644</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF45">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="495"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="672"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="798"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="956"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1169"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="680"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="988"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1019"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1111"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1175"/>
            <end position="1202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1224" mass="128471" checksum="59E4B1B162538E15" modified="2025-10-08" version="1">MDVPGETPSPQGVPMPGPGGMSGPVPGPQHMGHQQLQQQQHQQQQMNQSQQMSAADAAVVNKLTRGHSCVLCQQRKVRCDKNKPCANCVKAQVECRVVPPQPPRRRKKKPHERELVERLRKYEALLAQHGVSFDPVYDSHASSNGGGSHGGHHSTIDEVDELQNDLVGLKTSPSSSNQEYSSEANAAERERLKWSYRSSNEDTLRDDDDSSDDELEGSTIHHAFDSMFDNQDGFPFVIGGQTTKVTDHHPPGIQIFQLWQIYLTNVNPLLKVTHTQTLQAQIIEAGANVSKIPRPLEALMFSIYFIAITSMSEEDVQSTFDEEKARLVARFHRAAQQALINAGFMRSPDLVVLQAYFLYLVSLIPIALPTYQQSQICVRQYVDPRSLFCLIGIAVRVAQRLGLHRDGAQFGLPPFEVELRRRLWWQIVVFDKRIAEITGSTITALSSSNADTKFPLNINDTDLHLHAKDAPTPYVGPTEMLFCLTRVEMCTAAGSPDSGPPNAAGGNAANNNTAGGGSGSGSNSNTSGGSPAAASSSNPGAPGGGGGNSSNTAGATGGNNSSVAPVAGPAPPPGSAAATVAAATRKFHYSPSPSSPDVVTHIVNQTLPSDPESYCNYIENTYLKSCDPKIPMHFFTLMMTRQALSKMRVINFLARNGPAAAAAAAAAAANNGGGSGAGAGSSPSSNDAATPMNSSHSHSSFSPMGGMSSFGGGPGGMGGMGGGGMMGGDMDDMMGGMGGGMGNMMGGMMGGMGGMGGMMGGMGGMMGGMGGMMGGIGGMGGMMMGGGGGGGPGMMMGGPMQPTYGPPPPQAHLAPPAPPPPPAPPVVDDAERDTLFIEAIRMVEYDNIMQSADSLKGFAWYTYMHFPFPAYMFIVIELRTRKSGDLVERAWAAICENHERRGLIRNLRSPIHVAFGGLFIKAWDAHEAAEAQAGRTRKAPKFIQLLRQTLPKLNPGIVQTGQTGAAPGLPLPVSASGPPPQRPLPTTNNSSGNVKVGNVGNVGNRGGEEDMMEESVSRQQHQSAQQQQQLAQGLHPSSASSTTSSPPAAQQQQQQQQQQQQQQQHQQHQPHPLHQQHQPHQSHQQQHAHAQQQHQVHGSVYAQPTGATQTPGGGAGGQGGQGGQGSQAGNGGQGGQYFDNLGNPQMIGGVGVPDTMDFGPMDWSFFMQNEYNNGNGAGGPGQGTPGPGGRGPGGQGPPGSQGGQVPTSQGGSYANMYGQQGHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTN8</accession>
    <name>A0ABR3YTN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Luciferase" evidence="3">
        <location>
            <begin position="237"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="330" mass="36468" checksum="196F810418EA9E86" modified="2025-10-08" version="1">MPTSSPSLYPSPSPSRPSVSTSTSLSSLSLTKQHDAHTHTHQHHETGDLSLNMVIHQNPFSVTLDAWAMLVSSLLLITGMHFMQLSMLKAIIVAVPVALLVRNDYLNFLLLGPGGTPPTFVGYLRLLWLRMFALRDVYNSPPEADPNLAPSRGILKGSGDDQKELPYRPGPRPQVAGLAPQRQLDQQASTACYGQLRAAVENLTRQHPDTLCTATSCIEKHGFGLFARHPVNVWGQGEIFHIHDSEKSMHMSLHPDDIKEVLDKGWGQRHPLAFSAGWVKAPLPPTFVMIYAPRDESDLAIIARIVEAAIWYTMAQRVELTLPSAEPEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR7</accession>
    <name>A0ABR3YTR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Bcs1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_007549</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="BCS1 N-terminal" evidence="15">
        <location>
            <begin position="66"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="319"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="147"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="388"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="613"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="614"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="648"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="742"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="776"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="830"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="865" mass="95324" checksum="6EDB4E27351BA910" modified="2025-10-08" version="1">MATNASYNTVTDPMATASRASDPFASQSSAPSAALLDFFFPGLSVFTGALQRYLHIDLNYYFPLVLFLGGITFAWNYFSNYLYTQLEAHFMSTVEIRYDDEVYNMLMTWVACQPFAQNARRFIVNTMVGSRSWSVWELQYEERRRNAYDSDDEGSDDSDEDEEAAADTSPEGLKKKKKQKKALSYTPTFGTYYFWYRGSLLVFRRTQSRDTSVISSDQRESISVSCFGRNPTVLKHLMLETRRMYMRRDVHKTVIYRGSSSGGKYRVGEPTWMRCMARNPRPLSTVILNEKVKEDLVSDVADYLDPATRRWYANRGIPYRRGYLLYGPPGTGKSSLSVSLAGHFNMNIYIVSLNGVAATEETLAVLFNDLPRRCIVLLEDIDTAGLTHTRESSSGDKDKGGSGSGSDKDSDSDSESESDSSDSSEDEDGTKDGSDDKKKTDGDNDSKDSSSSSSSSKKDKAGRLSLSGLLNILDGVASQEGRILIMTTNHVEKLDKALIRPGRVDMMVKFDRADHDMMEALFRSIFATLEGDGVQVTNISNKDIEPKKVKSKEEVEEEEAAAAIRLDAYAKEFSAAIPELTFSPAELQGFLLKHKRDPAGAVKGAAEWVTTAKAAKDKAEKRSERKKEKAKAKEERKKQKEKAKKEKKATEKAAAKVKKEAKEAREKEAAKKKAAKKLLKKAAASSKKIGDEDSNDDLDAVALSDLDNSDSDADAQNTSGDEDSDVDINVYSSDTDNEAEKKRQKKKEKLKLQQRKRRQQQQQRSKSKSRAASIAPVSVPATITPSSSSASAATLPAPTKLIADPPVSSASSAADLSDRSGTSSYASSKATTVDSNSSDVDAVDVTKTTLDKAKKPTETVVVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU20</accession>
    <name>A0ABR3YU20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007503</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="3">
        <location>
            <begin position="14"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="170" mass="17300" checksum="54D9A1F4453E7F7A" modified="2025-10-08" version="1">MSADIPGSGTNDVLDETLGRLAKKAGVKATILLDRATGSILKMEGQISSIRTSIGSKNSGGGGSNGAAKDTSGSTMVDSGTSMAAGGGFAEDALLSGAGGDDGAPADETKGARELAGLVWNYVKTSGSLVEAIDTEDELKLLRLRTKKQELVIVPDPKYLLIVIHDTPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUD2</accession>
    <name>A0ABR3YUD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KIP2</name>
        <name evidence="10" type="ORF">Sste5346_007418</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="219"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="615"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="691"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="857"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="828"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="617"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="706"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="857"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="880"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="299"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="990" mass="105440" checksum="9D9326BB87F96E7C" modified="2025-10-08" version="1">MATGLPRTTRPSNGPPSTALPALPMAKTRKSMGSLPTPTVEKSAPNTPRSGLRAPSVSGLPAAGQSLTPGLLQPRAVSGVNGAGKTLRKSVSINSFPQPPRSDNRGTSLPPSPLSNGAPSSRKLKTPTTPNYTFSNSTPSLLNGTGEGKSVARPGQRSSDGLISVASPAQSRSSSAQDSYSTSATQYDDMGDLGPKSGLGISTDSGSSKRLSKADGKGNVIVSVRVRPDAGGQDHKTDGEWMVDGRKSLVAYRGKEGGDYFYDNVFSTHDNNSKVYDHIAKRLVRRVMEGYHGTVFAYGMTGTGKTFSMQGTASSPGVIPLAITDIFSYIRETPSREFLLRVSYLEIYNERIHDLLSMPTNAGVGGNVQQEEIKLREDSKRGVYASPLKEEIVQSPTQLLRVIARGDQARRTASTQFNSRSSRSHAVVQIVVESRERIPGNATGGDNKRGGLLPGGVRVSTLSLIDLAGSEKAAETKERRTEGSHINKSLLTLGTVIAKLSDSKDKDPKQADKDGKHLPYRDSKLTRLLQGALSGGSLVSILCTIQIGSVGSVATANSHTTETINTLKFASRAKNNIVSHAKRAEEALGAGGDGGARVLLERYRMEIVELRSALEAQAKKKSEESEEEERVKDAEEEAAREREAEHRHEEQMLEMQLARTALKERIDHLNRLILSSKSIGVNTGGSYSSLGMHPRSSMASVRSIATTNGGTSSGSRSLLERTASTASSSSTVGRSAGGQRLSGSASGTAEGSPAEDDDSAGEFGDGIASLSSQNQALQADLADKNRYIATLEKRLLQARRASSSRTSVGLGSTKGIMVGEDHSVSAVIRDKDAEIAELRARLEDKDRMLAALRTAARSRDNADRVDSRSSFRTSQMLEPPSSPPAMALPPTPAMSTGVKSPVLGSGKRHSSTGFPRARTKSVDEMSRMLDEMIQDRVESGQLVRGTRGSVRVAPNERKPDVVVAEPTINLEPLRRSPSLINEPAPVAMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV38</accession>
    <name>A0ABR3YV38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849">
        <property type="entry name" value="CHITIN-BINDING LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849:SF8">
        <property type="entry name" value="LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046695905" description="Chitin-binding type-1 domain-containing protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="59"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="184"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="291"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="106"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="337" mass="32947" checksum="033B7657B805A037" modified="2025-10-08" version="1">MRWTSITLSAALALSSTAYGSYGSNVMLGGAVGGIFQRHEPGQGQQGAASVLEGRQAAAGRCGTDGGNAKCPAGQCCSQWGYCGVGAEFCNPIALCQSDFGSCLGQSQSATAPPPPTTTAAPPPPPVTTTTRAPPPPPPTTTSAVPPPPTTTSAPRPPPSTSANPPPPVSTSPVPPGTLVPSTNGMCGNSTTCAGSGRGSCCSQFFYCGDGIEFCGTGCQSKFGLCFGGFSAPGPASSGTSKPAVPTTTSAAAPPPTSAPKPSTTTSAAAPPPATSSPAAALPPGVSVTTDGSCGNGKTCLGSTFGQCCSQFGFCGNGEQFCPAIVACQPEWGHCDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVI1</accession>
    <name>A0ABR3YVI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_007384</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046263562" description="Glucanase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="469" mass="48463" checksum="75AE840226B20A37" modified="2025-10-08" version="1">MSSSAAALLLFLGAAVAQQIGTAVPEVHPKLPTQFCTTAGGCKTMQTSLVTDALSRSLHAVGQPSVACNVANKTQCPDATTCSQNCALEGFNYAAQGVSTTGNAMTLRLFNGSGANIQTLSPRVYLLAEDDKNYQLLKLANQEFTYDVDMSKVGCGVNGALYLSEMDESGGRSAANPAGAQYGTGYCDAQCFNTTFINGLANFNNSGACCNEMDIWEANNAATAMTPHTCSGSGLFQCAGDSCGRGAAAVCDKNGCGINPFRAGAKNFYGPGGSVDTTKPFTVVTQFISADNTSTGNLGQIVRMYIQNGKMVSSATKSSNGSTSSLSALSTGLGTITEDFCTQNGATDFVRLGGLQGMGKSLARGMVLIFSIWDAPGDFMTWLDSGSAGPCSATQGDPKIIAMNNSDAAVTFSNIRWGDIGSTIRMSPNGSILANTDVAESKQTSGASLITLPMTVLSGLALTFGYLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVL4</accession>
    <name>A0ABR3YVL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007281</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="278" mass="29147" checksum="DA6FE6A5AFEE3F73" modified="2025-10-08" version="1">MAPKTLSIFSLEGKNCVVTGGAGGLGREVMSAFALSGANCACVDLNLEACNAAIADVRAHVQKEGGFEAPAEAFRAYAGNATDEPDVEKTVAQIAADFGGRIDVLVTCAGICVDAGAEDVDLATWRKVIAVNLDGTYLFARNVGKVMLAAKTKGSMVFVSSAAAAHPPRPQAQASYNASKSAVNALTVSLATEWAARGIRVNSFSPGFMVTPLMASQTGKTSHDEPLTPRQQEWLTQIPLGRFANPEEHRGTLVWMASDASSYLTGANIVSDGGWVHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWE8</accession>
    <name>A0ABR3YWE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS26A</name>
        <name evidence="6" type="ORF">Sste5346_007105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="120" mass="13645" checksum="0BB2A5F9A206E361" modified="2025-10-08" version="1">MVKKRKNNGRNKKGRGHVKPIRCSNCSRCTPKDKAIKRFTIRNMVESAAIRDISDASVFADYTVPKMYLKLQYCVSCAIHGKIVRVRSRVGRRNRAPPPRVRYNKDGKKVVPTQAKTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX85</accession>
    <name>A0ABR3YX85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">beta-glucosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_007101</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF16">
        <property type="entry name" value="BETA-GLUCOSIDASE J-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="410"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="873" mass="93693" checksum="AB96986C03DAF89B" modified="2025-10-08" version="1">MKPSDAVSGAPASPLDIESVLEQLSLDEKVALLAGIDGWHTKAVPRLGVPSIRMSDGPNGVRGTRFFNGVPAACMPCETALGATFDQDLVRELGQLLGQECKAKGAHVLLGPTINIQRGPLGGRGFESFSEDPVLSGTLAARYCEGVQSEGILATPKHLVCNDQEHARVAVNAIVTERALREIYLLPFQLALGQSAVAPGCLMTSYNKLNGTHASEHPRLLQDIIRKEWGYEGLIVSDWFGTYSVSEAVNAGLDLEMPGMSGFRGPALIHAITSNKVKEFTVDERVRSVLKMVNATLASGIPEFAPENMRNTPETSALLRRAAAESVVLLKNDNNILPLNPAKRTLVLGPNANIATYCGGGSAALPAYYTTTPLQGIKCKSQSPDLVSFTQGAYGHKELPLLGEHLKTDDGKVGYTFRVYTESLEENPDRKHVDELHMTSSSAFLMDYMHPKVKGDTYYVTMDGTFVPTETALYDFGLTVAGTGLLYVDGQLIVDNKTKQRQGTSFFGIGTPEERGSISLTAGQSYKIHVDYGTAPTSNLKVKNVVSFGPGGLRLGGAKRIDPTEGAEEAVKLASDTTQFDQVVVCVGLNGDWESEGFDRPHMDLPAGSDDLVKKVLAARPDAVVVVQSGTPVTMSWAPQTKALVQAWYGGNEAGNGIADVLFGDVNPAAKLPLTFPTTLAQNPSYLNYRSEGGRVLYGEDVYVGYRYYDAVGAEPCFRFGHGLSYTSFASKDLSVSVSDGAVKSSSINVSVSVTNTGDRVGSEVLQVYVSPPSTSSVRRPPRELRAFHKVTSLQPGETRSVSLSPLSLALATSFWDENRDAWLSEEGEYTVHVVGTGSDNTVSQTFVVDKSRWWTGLHGKVNAAENGVNGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYS9</accession>
    <name>A0ABR3YYS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine protein phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26588" checksum="5E87FAD6530A5BA9" modified="2025-10-08" version="1">MDPDCAICRAPATIACDCEARGLEMAISQAEKRMMQAIYDDIKTWVREHARDYILEYFTLLKDRRLKAHDQNMERIKQQAFYYHTQPHPAEIQQAQMAFKRGIDEDWQSSVQRYPEVLEYYYSLVNLTLPADDDPNVRDPPLSALSGSRKSGRRTAAPATIASGMESIGAPPPQPPPQPQRISMYGHPREIRGRTPPPPPASERMAPRTPVPRDRRSAFRQPPPPPSSYYPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ83</accession>
    <name>A0ABR3YZ83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="165" mass="18744" checksum="2F1851EEF2545EB5" modified="2025-10-08" version="1">MEGRVLKTRARVVSSEDEEEQHPPKRARLARRNLARLEKSTSTAASTIQASKDVFLRPGKSKPPSNLEEIRQRLDQPHDTPSPPESRYELYVEAVEAAETEATIVSQVERLLKHPETKGYRLVLNQAFLAYPEDAGFNEGLESPQPNIVEGLSLNEYRWFPVRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0E1</accession>
    <name>A0ABR3Z0E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS28A</name>
        <name evidence="4" type="ORF">Sste5346_006283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="68" mass="7782" checksum="14F27315DC2E0FB8" modified="2025-10-08" version="1">MDSSKQPVKLVKVTRVLGRTGSRGGVTQVRVEFMDDQTRSIIRNVKGPVREDDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0J6</accession>
    <name>A0ABR3Z0J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Glucosylceramide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">UDP-glucose ceramide glucosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">UDP-glucose:N-acylsphingosine D-glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HSX11</name>
        <name evidence="16" type="ORF">Sste5346_006426</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="493"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1893595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="528" mass="58451" checksum="3E086966410E34E4" modified="2025-10-08" version="1">MFDLMTQGLATVWGVWTFRHYSSPRRRAAVEALADHAAVPHVTVIRPTKGLEPGLYECLASTCRQTYPRDRLRVNLCVESKSDPAYPVLERVVADFPDIDVRIYIEEEDPLLHGTAGHVRNLGPNPKIRNISRAYRDVPAGDDSVVWIVDCNVWVSPGVAGRMVDKLFGLGPDGTPQHTPYKFVHQLPLVVDIGTSSKLGAALDEMFMATSHAKFYSAINTVGIAPCVVGKSNMFRRAHLDKLTDPAQNPTVLTAADDKRGRGVDFFSSYICEDHLIGDLLWRSPLKTPAGVAYRNHGLVTGDLAIQPMADVTAAAYAARRVRWLRVRKWTVLLATLVEPGVESLLCAFYGSFALTTWGYLLPPALAAWLPPTWGAMARCWLAIVAVWMAADWCMYRRLQACLCTEVDGDTPSFARGRRTGGLSSKGFASWARAWFGRELLALPIWTYAVLLGATVAWRGKQFHVRMDMSVDELDEQGRRVIREERTQGVAALKVKAVTKDSDEEPTTNGKTNGRSKSNGKAAKRRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1V3</accession>
    <name>A0ABR3Z1V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046617655" evidence="2">
        <location>
            <begin position="18"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="321" mass="31479" checksum="38FB56E6F7C6BC70" modified="2025-10-08" version="1">MKTSAIIVSALIGSAAAAVRRGNWSPDTDTGGGWAPTQSEGGWAPTQSEGGWGPSSSPDTWSSDCTTTTPPPPPPTTHSSIPPPKPTTHSSIPPPKPTTHSSAPPPPPITKTTYVTTSICPVTTTSICSGTVVPVTTHTTSVWTVTTECPPETPTPAPPAPAPHAGNGTTPHVPAHPAGNGTVPAPPAPSAPAPPGQESQPPTPPPPPPAPSAPPQQPEQPEQPGQPEKPAPPTPAAPETPSGNGTTPGHPGSPSSPETPSTPGQPGSPSSPQASKIPGGTSPVPGTQPPTVPTSDAVRASAGTTAIVGVLAGLAGAVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2H6</accession>
    <name>A0ABR3Z2H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="261" mass="27411" checksum="F878ACF03062694E" modified="2025-10-08" version="1">MPARTNGSVTTATTTKPKRFELPALDFKFGSLTEGTNIPPPLPSPIEEEPSELKSNKENKPSATSSSKTTNAAQRSADDAPSAPSQSASSPARTLARKRPADDIPASPTLSSRPGSIRRLFSRNLLNTAYANAEGNEGQLATSNSTATVAGSIMRPESRSDGSILDERRARRSSGWFRRLRGGGTGDSLASSNASIVGGAPSSPLSKRSSMLFADAKKPQQQQLAKPAGPPPPMIPELGELEAKVDLDEGSLGGDLFKNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2M1</accession>
    <name>A0ABR3Z2M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycine cleavage system P protein</fullName>
            <ecNumber evidence="6">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GCV2</name>
        <name evidence="9" type="ORF">Sste5346_005565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GcvP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049316">
        <property type="entry name" value="GDC-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049315">
        <property type="entry name" value="GDC-P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003346">
        <property type="entry name" value="PRK04366.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773:SF1">
        <property type="entry name" value="GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="GLYCINE DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21478">
        <property type="entry name" value="GcvP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="7">
        <location>
            <begin position="78"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="7">
        <location>
            <begin position="563"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine dehydrogenase C-terminal" evidence="8">
        <location>
            <begin position="890"/>
            <end position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1076" mass="116922" checksum="26DE8C1958D656E6" modified="2025-10-08" version="1">MLSRGLAASRHFHPSRLARAGARLAAPATSSASSTSAAWACKQCVRSVSSSSSSSAAVSWATSSAFAKKYQALDTFQRRHIGPDPTETEVMLKALSPPAKSLDDFIAQVVPADILTEHPLFPKAQSGRDDPITRAVNEPLPEHSVKAYAEAVSGENDVKTKSFIGAGYYDTLVPEVIKVNVLENPAWYTSYTPYQPEISQGRLESLLNFQTVVTDLTALPIANASLLDEGTAAAEAMTLSMNMLSASRARRTGKTFVVSHLVHPQTLAVLRGRADGFGIKVVTDDVTAAGFNETLEKLGEDLVGVLVQYPNTEGGVENFRELSSQVHKQGALLSCATDLLALTVLTPPGEWGADIAFGSAQRLGVPMGFGGPHAAFFAVADKYKRKMPGRLIGVSKDRLGNRALRLSLQTREQHIRREKATSNVCTAQALLANMSALYSIYHGPEGLRAIAERIMTGTRILERAASQLGLEVKATNSLFDTFVVKTPGGKADVLLQAALDRGCNLRKLNDNEVGVSNDEAKSHEDLLAVIGAFYEAAPAISGASTAESLESFLQTLLKEVEAGSITETKIPEEFRRTSKYLTHPVFNTHHSETEMLRYIYYLQSKDLSLVHSMIPLGSCTMKLNGSVEMATLRMPGFAQLHPYVPANQATGYKRILASLTDQLQDITGMDAVSLQPNSGAQGEFAGLRAIRRYHELRGDTKRDICLIPVSAHGTNPASAAMAGMSVVPIRCDAKTGNLDLKDLEEKCKKYADRLSAFMVTYPSTFGVFEPGVRRACELVHEHGGQVYMDGANMNAQIGLCSPGDIGADVCHLNLHKTFCIPHGGGGPGMGPICVKEHLEKCLPPLTEYFAADGDRQAFPPVSSAPFGSASILPISWAYNLLMGADGLKEATKITLLNANYLLSRLSPHYQILYTNEHGRCAHEFILDVRPFRESAGVEAIDIAKRLQDYGFHAPTMSWPVANTLMIEPTESESQAELDRFVDALISIREEVRAIEEGHVPREGNVLKMAPHPVHDVIGDSADKAWDRPYTREQAAYPLPWLREKKFWPAVARVDDTYGDLNLFCTCPPVEDTTGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2U2</accession>
    <name>A0ABR3Z2U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bax inhibitor family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31917" checksum="81DC585509913B8B" modified="2025-10-08" version="1">MASTAKYSPAAAVDPDEHLDYTQAPPSYQAEASASARAAADDDQERLFSGAPRASIDGDDDADLPDDFKFGGSVAEATISIRNQFVRKVYAILTIQLLATSALGAVSFLSEGYRNWIQTHPALVFVSLFGAMGFLGLTYWKRKSYPANLLFLGGFTLLEAYSISVIVSFYEVGIVLNAVVLTAGIFVFLTLFACQTKYDFTSWMPYLFGALWALILFGFMAMFFPYSSTTELIYGGITALIFSGYILVDTQMVLRKHHVEEEIAAAISLYLDIINLFLAILRILNSQQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z319</accession>
    <name>A0ABR3Z319_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SMC5</name>
        <name evidence="7" type="ORF">Sste5346_005831</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="98"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="284"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="706"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1141" mass="130399" checksum="411B5FAFBCD8D875" modified="2025-10-08" version="1">MAGSEVSGSRPRRPLDGITDDNSLLHPNPNERPAKRMRPSLEPDEANGFDIGENDVDDDDDEAANETYYSTTSNRQSNGVAANTARVKAKPIFQSGAIVRVTLDNFVTYEHAEFDPGPSLNLVIGPNGTGKSSLVCAICLGLGFHSNVLGRATTFGDFVKHGRSHAIVEIELQARDDELENHIVRLRINREDNSRKFWLNGHEVPLKRVQSLMAELRIQVDNLCQFLPQDRVAEFAGLNAVDLLAKTLEAAAPVDMKEMQATLREIYHRQGNVEKQIKIDTEQLRLLEGRHQMQQADVERYREREEIQRVINDLEDCQPLVHYYEAKRKHRELKDDRRRANRDLSALTARLQPTLEAIDAKKQYQRQLEAGLSKRTAVLQSAEQAVGQALANVERFEDKIQAATAQHAKMGETRDKKRQDISATRQKITSLEARIKNKPPEFVASEWNMKIRDKEHQRREFEQERGEIQSEMTRVKGEFLRVQDERKAVEDEKQALESQRGQQLSFLRRVSSDAAKGWEWLEAHKGEFSKEIFGPPMVTCSIKDPQYSNLVQSLMQNDDFLCFTAQTVEDHKKLSDQFYRVMELSVTIRTCATPFSSFRSPFTPEQLSSMGFEGTAINYVEGPEPVLAMLCIERRLHLSPVSTQHPRQDQYDTVVANEHIMTWASKDQAYRVSRRREYGAHAVSTSVRDVRQGRYWKETQADMSEMTEIQQRLDAKNSELRGLQERMRSLRDKAAEPLRMISEVDKEIENLRAEKNQLQTEHNKWLALPEKVLAENNTLSQLREEHADVTTQRQQVVAKLDDLIMQKAKAVLRHAEHVERLRNAYLAFMEVQIREVEAASDVEGLQAQNSHLTTLQAQKQQALAGIIANMDVQRKIGEDAIREAEKIAREGSERSETLHALAQTKTTEQLQNEVAAERAKLELTRAVDEDVLDEFEQRAAKIEELQESLAAITAEFDGMGAQIADVRGRWEPRLDDLIGRINDAFSYNFEQINCAGEISVNKDEDFDKWAIDIRVKFRENEELQKLDQHRQSGGERAVSTIFYLMSLQAMAQAPFRVIDEINQGMDPRNERMMHERMVEIACHEHTSQYFLITPKLLPNLKYDENMTVLCIASGPYVPNGEAKLDFRKCIAAQRRLLTGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3B1</accession>
    <name>A0ABR3Z3B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Branched-chain amino acid aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050571">
        <property type="entry name" value="Class-IV_PLP-Dep_Aminotrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743">
        <property type="entry name" value="AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743:SF11">
        <property type="entry name" value="AMINODEOXYCHORISMATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36064" checksum="F12D058C81843388" modified="2025-10-08" version="1">MATMQKVFDAYEQRVATLQKSDNKYARGVAWIEGELVPLHEARIPLLDEGFMHSDLTYDVPSVWDGRFFRLDDHLDRFIASCGKMRLKLPLPREEVKATLVDMVAQSGIKDVFVEIIVTRGLKGIRGTDPKDIVNRLYMFIMPYVWVMDPSVQMNGTGSSIVARTVRRISPGSFDPTIKNLQWGDLTRAMLEAQDRSATYPFLTDGDAHLTEGSGFNVVIIKNGVLYSPARGVLEGVTRRSVMDAAKQLGYEMRLEFVPIENVYQADEILMCTTAGGIMPITTLDGKPVADGKVGPITKAIWDEYWAMHYEDTYSFEIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4S3</accession>
    <name>A0ABR3Z4S3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005099</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06564">
        <property type="entry name" value="GH20_DspB_LnbB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052764">
        <property type="entry name" value="GH20_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678:SF1">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045833570" description="beta-N-acetylhexosaminidase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase bacterial type N-terminal" evidence="8">
        <location>
            <begin position="118"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="7">
        <location>
            <begin position="186"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="761" mass="84138" checksum="8A044746C6CC7071" modified="2025-10-08" version="1">MARLSITCLYLLVTLLGGFLEHADSTSYLEGIPTIPFTSHDSSQGNGFFSLRNVQKIIIDKKYANATDQDGSTLIPPTLLQFANIFVEDVQTIFKLSMDVELASQHEEGQVFLTVDRGRNGFVDAAGRFTSEGYQVEVNATGIIVTGASPLGVWWATRTLLQQALLHKDISIPWGRGTDNPGWATRGVMLDVGRHFYPADFLVEMCAYMSFFKQNTFHLHLSDNLWNNPRYTTDDFMGLYARLRLWADDNEVAVRGLNRFANESYTRQQFDDIQTRCAARGVTVLPEIEAPGHALVLTQWKPQLAYGRDMSLLNISHPETIPTMKAVWGVFLKWFHCKVVSIGADEYQGPAGDYYYFVNILAGFIGAHSGKQVRTWGMFPPARDGPVGPPGSARRPIFQNISIQHWEFFEDDAYNDYIRNNYSVVNSNDDFYVVNKYGGEGGYPNRINVSRTFGDGDSGSGPWRPNLFDQHNATRNPPADNPYILGAIAALWNDPGPNASVYSEAYYAWREGIPALADKHWGGNLSGGAFNRVFAKIHPYTPGQNLERRIPSNGPVVFNYTFDKLPALQSANTLSPSPLLTRVVDTSPNGYDAETDCSISTETLADGSSTFVNITPDCSLRTPLTSKGRNYTLALSLRITSKDDPTNTTLLSGRDSALMLTPTLTLFASGNYYRLPPSKISFDDWVDVRIISRGNQTFAEMTPSSSSHGTTIRQEFRAEIGLHGDGMKSVEIAIEAPLHTLGGAGSGWTGQARSFSLSSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4V4</accession>
    <name>A0ABR3Z4V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20467" checksum="A6087E6DE3FB84D5" modified="2025-10-08" version="1">MPVFTKWLKRLRPPLAPRVFPTTFPRIDASTKHVTLKVFIRDQDLGQHANNEINTYYKIPAVAASSSHPGRHAVRSVLDHLPPVTSPAGNSHQCLVHAPLWDTARDLLYMNDTRRFTPLLTAMTLLPLLLALDFLHSECRLVHTDIKADNLAKEVANDHYIYTYQAIAMPESLGYTVAHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5J3</accession>
    <name>A0ABR3Z5J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Double-strand break repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">MRE11</name>
        <name evidence="20" type="ORF">Sste5346_005290</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16 17">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16 17" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16 17" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 16 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 16 17" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 16 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 16 17" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 16 17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="19">
        <location>
            <begin position="290"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="620"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="626"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="657"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="699"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="739"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="768"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1895482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="791" mass="87785" checksum="8E056781EFED832C" modified="2025-10-08" version="1">MVRNTEPDTIRILVATDNHVGYEERDPIRKDDSWRTFDEIMNLARTQDVDMVLLGGDLFHDNKPSRKAMYQVMRSLRQNCLGMKPCELEFLSDAAEIFEGAVGHVNYEDPDINISIPVFSIHGNHDDPSGDGHYCSLDLLQVAGFVNYFGRVPEADNIKVKPVLLQKGATKLALFGTGNVRDERMFRTFRDHKVTFFRPNQQANDFFNLMVVHQNHHAHTATSYLPENFLPDWLDLVVWGHEHECLIDPQKNPETGFHVMQPGSSVATSLVPGEAVPKHVAILSVTGKEFSVEKIPLKTVRPFVTREIVLAQERRFKDLARKKDNRAELTKRLMVIVEEMIEEAHAEYLSLHDNDRAGGDDENDDDDDEPPLPLIRLKVEYTAPEGGNFDCENPQRFSNRFAGKVANVNDVVYFHRRKTTAGQTKAGNAALPGGLRDVEAGADFNAIKVEALVDEYLAAQSLKILPQGEFGDAVNQFVNKDDKHAMDTFVSGSLANQLKDLLALGAEDGELDTAIERLRDERERQFQAGLVKQRHKRMYKPKPDDWDSDMEGHWEQHPGALIDQGGAADTPAPGVSQARLQLDAVRARATAASSRGAPNSLDEDLMMDDFDDVGPIAKTTAKRTTKAAATTSRAKATMRKAPVAKRSAPGRKKGPFEDSESDEDALMLDDDFDDDEEADEIEDDEMDEPAPPPTRRGRGAATTRAPARAAPKAAAKAAPKAAPKATKPAASRMRQTSLQFSQSQAAVPSQQPRAAASTSRTKQVQEISADEIEDDSDDFEPPPTARTTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5L6</accession>
    <name>A0ABR3Z5L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005029</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF45">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="18"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="493"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="522" mass="56494" checksum="9E06C2AE82E2BEDE" modified="2025-10-08" version="1">MGAKYLGFRGQKLHLAMLVLVVAPSFILFGYNNGSTGGIASLASFTKQFPDYNTTSGTPSVNAFHSRVKGVVTGCYDLGAVVGSLLCIFYSDKIGRLRTLLTGLLLTIVALAIESSAFTLAQFVVGRVLIGAAIGTISAVIPVWQSECASSAHRGTFVIVEGLSISFGITLSEWVAFGFSFVSNEGAQWRVPLAFPVIFAFFVIPFVFIMPESPRWLARVGRIDEARAVLAALADEDEDSPSVQEELRGVEHSLALVSGNFSELFHNGEERVLHRASLACMGQLMQQFCGISALVFYTSTVFVSLGFEGVHARVMGASLTTFQTLASIVPIFLIEKVGRRKLFMAAGTGLAISCAIVAGTGDLPGHKSIAAIVFFFVYDFFYPLGFLGQTFLYASEVSPLRFRVPITAIANATQWLSQFVVAQVTPPGTDNLGNKYWIIFAVINAAFVPIVFFFFPETKGRSLEDIDIIFRHTTSIFDAVSVAENMTTEQVRQEEATTVGENEKESVASASEKENVTAQTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6W1</accession>
    <name>A0ABR3Z6W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ribosomal 40S subunit protein S9B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RPS9B</name>
        <name evidence="11" type="ORF">Sste5346_004761</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="10">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="105"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="190" mass="21932" checksum="B7AB596172F931F7" modified="2025-10-08" version="1">MAPLSYSKTAKVPRRPFEAARLDSELKLVGEYGLRNKREVWRVLLTLSKIRRAARQLLTLDEKDPKRLFEGNALIRRLVRVGVLDDSRMKLDYVLALKVEDFLERRLQTLVYKLGLAKSIHHARVLIRQRHIRVGKQVVNVPSFIVRLDSQKHIDFSLKSPFGGGRPGRVRRKKAKAAEKGDGEEEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z799</accession>
    <name>A0ABR3Z799_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRP45</name>
        <name evidence="6" type="ORF">Sste5346_004564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="5">
        <location>
            <begin position="195"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="346"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="520"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="564"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="649" mass="70940" checksum="EE622BAE24D5C9AE" modified="2025-10-08" version="1">MASIASSLARSLPKPKYTGEDEEAPVRAQRGPRIISAAEIDETQVVLKRTTAPPYGKRQGWRPRTAEDFGDGGAFPEIPFAQYPLDMGRPGGAASKTKSNALAVQVDGEGKVKYDAIARLGHTEGRVIHTSFKDLIPLRQRAEAGDLNLDRPDQESVAETTERTKNALALLVSGAVAAQKPKTLAHLGGQRKEATYVQYTPASQFGNNDKKQDRVMKIVERQRDPLEPPKFKHKKIPRGPPSPPPPVMHSPPRKLTAADQEAWKIPPPISNWKNPKGYTVPLDKRLAAAGKGLEDVTINDKFAQFSEALFMADRHAREEVRQRAQMQQRLAEKEKLQKEEHLRELAQQARAERAAAAAGPSSSSRRQDGRGRSRSRSSSGSRRSRSRSYSDSRSRSQSRSYDSRSPSRSRSGSRSGSEDPEEKAVRAREEARREKRREEERKLRQSRMGAERRMQVLAREQNRDISEKVALGLAKPTASAEGMYDSRLFNQTSGFDSGFNEDNPYDKPLFAAQDAISSIYRSRGGPNGAGDDEFDDPAAGDAEMAKIQKTSRFGEALGRGTFKGARDVEAREGPVQFEKETTGLGVSGSGPAGSSAAADPFNVDKFLSEVEQGQGGGASAGGGKRGYGLQADGGSSSRQSKRARVEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7D7</accession>
    <name>A0ABR3Z7D7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF812">
        <property type="entry name" value="VPS9 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="341" mass="37414" checksum="88450F33AF6E013F" modified="2025-10-08" version="1">MAPLLFITGASGFIGSETVAHALEKGYRARLAIRRTEQADELRKRFADSGKAHELEFAVVPVIDDKAALTAALQGVDHVLHVASPMPSTNADLQTGYVQPAVRGTMAMLEVAATIPTIKRMIIMSAYLALAPLDISTRNGFEVKEGANASIEIDYEAIPEGAFGDVYKYHISKLLAHRAALEWVAKTKPNFDVLTVHPYYVIGYDRALKHDPATGAVQPRPIPLFYLLSLQSDAPLLSSAYVDVRDVAAMEIGAITVEKNLKPRGEITEIIALGPRISWPQMREFVKTKFPDFPLKQTNDGNFSEPLTSNTERATCDMGLVLRDPYETLSVTLVQHGPLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9G9</accession>
    <name>A0ABR3Z9G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ntf2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="65438" checksum="61689AB0F2533828" modified="2025-10-08" version="1">MALQAAYQQFLGAPNSANLTADASLYYITTSTIVHGSTEIIKHFGTLRKQLKKNKEAVLSSVESANGLALEIDTTLEFITSGGPYLPRLDDNFLSDRKVYLPVTHFVSFDAEGKITQIRQSWDQGALLKQIDVIGKSGRNWPISDGTEQVKLITTAVSAVGASQPGGASAAGGANTALPVRPRGNSALRDPHASLELFGSREQMETLPAAVVPPYAGVRPKQRDVTDILNDNPPDEEAAANAVVSPYAGRRPQQRSFNEILGDEDDEDEEGDATGDSPSRGRSVGSRARSRSPTKSIAPKAGSNKNYQPVRLFEADEAAAAAIDASSPEAQRFYRPNPKRYNHFDFADGSDPQDAPKAGTAFDALPKTKHNSQWSFEDFATPQKPPPRATRGQEVRHFGIENDEFPETPSAASRKPVQLKPRRDAETHFEFQDDGEPSGEPRAAGKPRGAGHNDGLGLYKNNLYKEDGTAPTPGPARALGNITNLKDRSKIFEAHFVMADKQPVEADAPEPHGISDDRKKAVQMMESHWGADFDDKEGAQKENVSIPGTHVSGKGDDSRGIQIGGDGMGGKKSGRSWSFGGEDEEAAPAVPGKKPNKATQASDFWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9X4</accession>
    <name>A0ABR3Z9X4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA polymerase II subunit A C-terminal domain phosphatase SSU72</fullName>
            <shortName evidence="10">CTD phosphatase SSU72</shortName>
            <ecNumber evidence="10">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SSU72</name>
        <name evidence="11" type="ORF">Sste5346_004499</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the cleavage and polyadenylation factor (CPF) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SSU72 phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006811">
        <property type="entry name" value="RNA_pol_II_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20383">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04722">
        <property type="entry name" value="Ssu72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="261" mass="28550" checksum="09D7E81073E278A7" modified="2025-10-08" version="1">MAATNGADVAVAVPAPPVGAPGVEDNGGFKLKFCTVCASNQNRSMEAHLRLAQAGFPVISFGTGSLVRLPGPTVTQPNVYQFNKTSYDSIFRELESKDVRLYKANGVLNMINRNRGIKWGPERWQDWQVGLPRIEHTTDMGSVGSEGGVVDIVITCEERCWDAVIDDLLNRGSPLNRPVHVINVDIRDNHEEAALGGRGILDLATVLNRAAAEEREKVGPAVFDAGGAASRSSFDERVPDILAEWQERWPNLPSTWTLAWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Y2</accession>
    <name>A0ABR3Z9Y2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RmlD-like substrate binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="5"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="317" mass="34649" checksum="CCFC29CB3BD76A69" modified="2025-10-08" version="1">MSDKRVLVTGASGLLGRQVVRAFEQDGWSVTGTAFSRANGTTLRKVDLEDGSAVAAVLEDVNPTVVVHCAANRFPDKVDKDPQGTKRLNIDASKSLASLCADRNIVLIYISTDYVFPGTKGEAPYEADTKPSPPNLYGESKLDGEKAVLSTYAESKTSGRAVVLRVPVLYGQAEKPAESAVNTLLDTVNKVQAPDASAKMDHWSIRYPTNTEDVARVLKDVANKYRSAEPSTTLPPVLQFSSEDRYTKYEICQLLAEVLGVGLDRLEADPTGGNVPGGVQRPYDCHLSTKALKELGIPVHTQNFNDWWRRELKAFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA69</accession>
    <name>A0ABR3ZA69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Guanine nucleotide exchange protein for ADP-robosylation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEC7</name>
        <name evidence="9" type="ORF">Sste5346_004362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="664"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="295"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="637"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1063"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1358"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1582"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1899"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1069"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1363"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1596"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1611"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1635"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1648"/>
            <end position="1668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1962" mass="217459" checksum="8E88CBB30C28F358" modified="2025-10-08" version="1">MSSLKFVAASLGVIAAAKDTSHNAPLADAVKKALAAIKENDPQFPDPEIIFAPLQLATRSGSIPLTTTALDCIGKLISYSYFSIPSASATAASAAADAASTDADEDPQSQGAAASTEGSSDPADRAPLIERAIDTICDCFQGDTTPAEIQLQIVKSLLAAVLNDKIVVHGAGLLKAIRQVYNVFLLSRNAPNQQVAQGTLTQMVGTVFERVKLRLQMKESRLGLSKLKHNGSNATFEQPDGARASTAYEGEGDESPDAASVATTPGLASDAGSGANGEGGAEAKLTLKDLEHRKSFDDSNLGDGPTMVTHLKRGPTSSARSVSEQTNPDSPHEEAPESLDAEDEVYIRDAYLVFRSFCNLSTKVLPPDQLYDLRGQPMRSKLISLHLIHTLLNNNISVFTSPLCTITNTKSNEPTSFLQAVKFYLCLSITRNGASSVDRVFEVCCEIFWLMLKFMRAPFKKEIEVFLNEIYLALLARKTAPMSQKLYFINILNRFCADPRSLVETYLNYDCEPNVDNIFQTIVESLSKLAITPVPIAADIERAYEEKHGSTSGSDWQIKTSLPPPLTVNFIVPHHAPEPEFPQEYIMKRVSLDALVESLRSMVNWSQAGRPDGGAMAAAAADVDRRASVDDVRESIDPSISDSVSRVDTPVLPSTPVMDDDPEQLEKEKARKTALAAAIRAFNFKPKRGLKMLIDQGFIPSDSPQDIANFLIREERLDKAQIGEYLGDADPKNIETMHAFVDTMDFTKRRFVSALRQFLQSFRLPGEAQKIDRFMLKFAERYNDGNPNAFANADTAYVLSYSVIMLNTDLHSNNVVKRMTQQDFIRNNRGINDNADLPDEYLIGIYEEIGSNEIVLDSERRAAAAAGTLPVQQPTGLASAFTNVGRDLQREAYVQQSEEISLRSEQLFKNLFRSQRRNAAKAGSVKFVPATNFKHIGPMFDVTWMSYFSAFSSQMQNAHNLDLHRLCLEGMQLATKIACQFELSTPREAFISALRNAASLNNVQEVYAKNVEALRVLLELGYTEGNYLRQSWKDILISVSQLERLQLMASGIDASAVPDVSKARFVPPSKDRGSTSSDSRKSMQRRQRPRAPTGPNGFSSPEIAYDLTSDDTIKSMDRIFTNTANLNGEAITHFARALTEVSWDEIKVSGSNDNPRMYSLQKIVEISYYNMTRVRFEWTNIWDLLADHFNKIGSNANEAVVFFALDSLRQLSMRFMEIEELPGFKFQKDFLKPFEHVMANSKNIHVKDMALRCLIQMIQARGENIRSGWRTMFGAFTVAARDPAESIVNMAFENVTQVFRTRFGVVIAQGAFTDLIVCLTEFSKNIRFQKKSLQAMETLKAVVPKMLKTPECPLSQRHLAGAANGGSNGTHNGDGAGETDLKSPQPSRTSVEEGFWFPVLFAFHDVLMTGEDLEVRSNALNYFFETLLRYGGDFPPDFWDILWRQQLYPIFLVLRSRPEMSNVLSHEELSVWLSTTMIQALRNMITLFTHYFDALEYMLDRFLELLALCILQENDTIARIGSNCLQQLVLQNVGKFSQEHWSKIVGAFCELFERTTAYQLFSATTINSTASLSPPPGALEFGYPLSPGVPPDGTFADEKSLKINGDGHAEGSSSQLPDSDTASTLSMPSAAVASESEDGEDEDGNDPRTPTAQSIASVISGNGPSLSQPLEDYKPTSNLQQQPVVVTAARRRFFNRIISRCVLQLLMIETVNELFSNEAVYNQIPSTELLRLMALLKKSFLFARRFNNDKELRMRLWREGFMKQPPNLLKQESGSAATYVSILFKMYADQAEERQSKRADVESALVPLCKDILQGYLALEDESQHRNIMAWRPVVVDVLEGYAQFPKPAFLEHLSDFYPSMIELLGRELSGELRVAIVQVLRRVGEVSLGLSGLFSGHGAGSHGSGEYDDTSLQGKRRRRGDSVLSTATTTTTEGGNVDYEGGDASTKFMGRRMNSPSVAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAZ6</accession>
    <name>A0ABR3ZAZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="363" mass="40905" checksum="A46DC4D485888776" modified="2025-10-08" version="1">MAEPKTQQAEAQIERLERLNTEGFPDKHATMDDEIREYVGGAEAVEVDPATSTRLRRMIDKRVLVVMLGTYFLQSLDKNALSFTAIMGIRTDAHLVGQDYAWLHTVIYFGILAAEFPTVLIVQKVPIAKYLAANIFLWGLTVTMTCFGFNFTVLTALRILLGLFEAVSQPTFLLLSSMWYTRSEQAVIVACWYGMNGVQGICGGLIAYGISHIHSTVLKSWQVLYIILGSITCVWAIFVSWWMPDSPMRAKCWAKEDRLLMIERVRANQTGIQNRKLKRSHVMEAIKDPQVWCYVFIQVIIQIPTGGLGSFSTIIISNFGFTTLQTELLSMVNGVIQCIILLGAGWLVRRYSRAVIFQLVRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB13</accession>
    <name>A0ABR3ZB13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ-related protein scj1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SCJ1</name>
        <name evidence="10" type="ORF">Sste5346_004174</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045483350" evidence="7">
        <location>
            <begin position="22"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="148"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="148"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="420" mass="47566" checksum="3CA5E6004E05602D" modified="2025-10-08" version="1">MKVFTNTVLLVLFSLLHLVLAAEDFYKVLGIKRDAGDREIKSAYRQLSKKYHPDKNPGDDSAKDKFVEVSEAYEALSDPQTRKIYDQHGHEGLKRHQQQQGGGGGHHDPFDVFSRFFGGGGHFGQASERRGPNLELKVQISLRDFYNGQTVEFHWDKQEICEHCDGTGAADKHVDTCDKCQGRGVVIQKHQLAPGMFQQVQMHCDRCGGRGKSVKHVCPVCQGQRVVRRPTPVSVTIQRGIAKDARIVYENEADASPDYVAGDLIVSLGEKEPSPEDNPDHVDGAYFRRRGNDLFWKEVISLREAWMGDWTRNLTHLDGHVVELKRERGQVVQPGHVDTVAGEGMPIWHEDGDSVYHKTEFGNLYVEYAVVLPDQMESGMEKEFWSLWQKWRGKIGVDLQKDSGRPDRQAAKADRLHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC48</accession>
    <name>A0ABR3ZC48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123559" evidence="1">
        <location>
            <begin position="18"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="212" mass="22114" checksum="04E601DB1B02F400" modified="2025-10-08" version="1">MRLSSIINLLAASVVEASLCRPSKPAASVSSSSSSPSFSPSPSTIPCNTNRLIDQSRGVSPPTAWQYAPLSGVTVSYPATCNNNAYNQAPDGSCVNFLLREAPPSAVTAVTISRALDTVVGTTYSFGFSFRIGSDEPDANAGDVNKIVCSADNTAQSNGWAPFFLGYPEDTLNDFGISFTASAATTTVTCVLTVDTAIDFTVSNYYLSALCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC84</accession>
    <name>A0ABR3ZC84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208318" description="Carboxylesterase type B domain-containing protein" evidence="3">
        <location>
            <begin position="16"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="17"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="594" mass="63007" checksum="CD741B47E35F2349" modified="2025-10-08" version="1">MKTLSVLGLAALAQAVDPLVTLNYTQLQGSAIQSTGVTQWLGVRYAAPPVGDLRFAAPINPPATTGVQDATQFQAICLPRNPSDFTMHSKRLNVSEDCLFANIFAPSNATNTSALPVLYFIQGGGFSSNSNANFNGSGLAAFGNIVVVQINYRVGPYGFLQSREVQNNGSLNNGLKDQIQGLKWVQQNIAAFGGDPKHIVASGDSAGATSIGLLLAAWDEQDPRLIKGAILESPSVATIRTLEQGQEQYNCLLEATNCTLAANTLNCLRSVNATDLQTEQCQFNPHLDNDLVRRPMLQSFDEGRFLHIPIIAGTCADEGTKNVPAMTNTTGQALQFIDNRVSNVLSNTSLALLNTTYLLTNHTGAIAVANTFAEFPNSGPLWRPLANAAGDAGAHCITARLQNAIAREGVKTFNYRFAVRDDEQERLGFGAYHTVELNAVFGPNNTDGNPPKSYRAGQSNAGIVPVTMAYWTSFVKALDPNDLKLAGTPDWTAWAGPEGRQRLRFQTNATGLETMPDDQVANCEMLEPMLPAIESISAPGVTVTLNPRGQKNGTSWAKTAGQKQKSAAAGRAGGASLVGTVVGLAAAVAALAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC96</accession>
    <name>A0ABR3ZC96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF2">
        <property type="entry name" value="PEROXISOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="299" mass="31159" checksum="F4FC6AAD9EB69F49" modified="2025-10-08" version="1">MSKLSASLKTLINAPFARPGPTAAPPRIADVYRSIARDAAKKNVGSQPWITFSAAATITLNSPDALAVLWRVASDQQPTPALAPVASAELIREVGLKCIGFNGIPRTINVLGSFRNSGLPQDIVAQLATTPTRAPTAEGLSETTERGLGLWRSVYAGVDVKLLEKLAESHPDLPVHILNSHYGPLFTDPPNHAAGGLATVGRALTSLVAIACLRAQTGVGPQVVSHIFGLRKAVSDGSWLLNGEAGASAEDRESVRGVDWLATDEGSEWLLQSIDRIVGALGGSNFAGGGEGDAPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCD3</accession>
    <name>A0ABR3ZCD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein required for normal CLN1 and CLN2 G1 cyclin expression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CTR9</name>
        <name evidence="6" type="ORF">Sste5346_003998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031101">
        <property type="entry name" value="Ctr9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027:SF2">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="801"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="929"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1080"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1102"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1121"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1237" mass="138292" checksum="C5EC94453436A0CF" modified="2025-10-08" version="1">MSSTLRNGNHGGANGGFAHPASKRFTDVPIAIDVPTQDEDEAVEIGLENLVDDPTDLCDLFENENAARTYWMTVSLAYAKQGKIENAIEMLIRGGNAMQNSNPKEKLSIVACLCWMYLWKSRLAPRVRPEGVSLSEPRTKDDFLKAATASLNDAARINPAYPPIFLARGVLLLLQASLQVSTTTSGGGAGPVAGEKLDLLRSAMKSFDDALRVSGGKNMLALMGRSRALYSLGKFAEALSGYQEVLTKAPELVDPDPRIGIGCCFWQLGFKEDAKAAWERSLEITPDSKVANILLGLYYLDKSGQVATNSPEFLRLYKKGMTEYTQKAFKLDKNMPLTCATFAGYFLSRKAFTNVDSLAHKAIQSTDINAVASDGWYLLARKSHMEGDIERAADYYRRSDNARGGTDRGYLPAKFGAAQLSVAKSDLGEAKLQLEKMIQQSKNLEAMALLGTLYAEEVFANDRAAVKEDKAVEKKKAISLLENVRTAWKDPKKHLSPDAAVLLNLAWLYEADHPDRALQCLQQVEQLELDQIAESAEPAAEGVDAATHRESLRKFLPPQLLNNMGCFYFQSDKQELASNMFELALDACVKIQNKEDEDTDADALVTTISYNLGRSYEARALVDKAVEAYEGLLKRHEGYTDARLRLAYVKLRKSPNDAGPDAVAKLYQENSSDLEVRALYGWYLGKAYAKKRPANINEDHELRHYKHTLQNHDKHDRYALVGMGNLYLASAREMRRETDQEKQKRSATYSRAVEFFDKALQLDPKNAYAAQGIAIALVEDKKDYRSALPIFLSVRDTVRDHHVYVNLGHIHAELRQFSKAIENYEAALAKEGKSNDPTILSCLGRVWLQKARTEKDLEAFKMCLECAQNALAVAPDQVHFKFNVAFAQIQLASTIYSLNESQRTLEQLQAAASGLEDAIKALDEIAAHPQTPYPKQDVEQRANMARNTQRRQLERAIASQKDYEEKNKEKLAAALEQRQVELKRREEERQKALDLQKERQEKIRKEREEIAARDRVLAEKRAEEEKARREAEMTTDSETGEKVKRKRKPAPRGDREPRASGGSKSRSRKKKAADDDDSDGDNRSGDSDAEDRHQKKKRRLSRKEPPKNSKYKSSELVHSSDDEDDDYDALDAADAAIEKRNRRGGSAGSDDDDGARDDASDRMDVDEDEDNEGGGRSQQKRSRRGARVLDESEDEDEEPAKADDDGAASDAAKDDEEEAPAARRSRRRAVSDDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI7</accession>
    <name>A0ABR3ZDI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="767"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1091"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1137"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1156" mass="124875" checksum="2E96D8484DAEF1AC" modified="2025-10-08" version="1">MAYQEHDDTAYAGDAEGPASSASPTAASFRRRQSSRNRDFGLFASRLRQNQPPTKHQDTASDVEPLGFDEGASPAANGSQQQSRIHTRDNGSSSTSSSSKTTGRTLLSSPRTQSHKNKFDFDDSFDDGPDGGDSDHDGSTRPPSHISPLPRSPTSPISPRWASLANGSAAYSYSGSSNITVSVPVSSVHTSIASAGFSTAPTSPISPTHSTFAAKSLFRSPSSSSSSAPRFAGLSSHPFVPNTIAPGRTSSSTEDSLSPSDKPAPFPNTANTPSIPPAPLFPELQSPPPPPPPVAPSAMIVGNFSRPRQLSIKQGPRDALPPISTRSHVPDPLQLESPAPAATVSKQSTWPRERARGMSVSSNKSSSTYSSATNRPSTDNTRPNRLVASSTQPQNAGVISPGLPRPPLAYSRTDSTGSNSTNAGPQLLSTQSMSQLRDPAFARADEESRSSYRSQWTSSTAQKTVFTDAGTARSSVLTKTSSRASMSWFTNAPPGADDGLSVDDVMGLYEKGFGDSTGAEDNDGPYGGTAAGKDSGDEDFTDAEAHDGSLTPPGPGPQPEQDVMGSGMIGSQILEAMSDPLPIPPRSTKRVGSPDDAALDTPRPVRYSGLSSSVPKDSGFGLVTQHMNNKQLLVPNAEDQDDAKEKRDSAKMLESDDKPSGKPSPLSSPQLNTSFDSRPGSAKAPSLFARAHDESDDPAMRDRYGFRKHNQYISREQYDAWNGPYTEYIGRRRRKWVAYLRDSGLITDKPTRFPPPSVKTKRFIRKGIPPEWRGAAWFYYAGGPSIIAKHPGIYKQLLARAARGEAKEVDVESIERDLHRTFPDNAAFQFSGDQQPGHGDPDVTGKANMDITIDRPEEPKIVSKLRRVLLAFSIYNPRIGYCQSLNFLAGLLLLFVETEEHCFWLLNVITRIFLPGTHEMSLEGSKVDLGVLMAAMQESLPGVWAKIGGELEDSTPANRDAQKQGAIGRKMKLPRVGGNKADALTAASADRLPPITLCMTAWFMSCFIGTLPIETTLRVWDIFFYEGSKTLFRVALAIFKLGESEIRAVSDPMEMFGVVQGLPRHLLDCNMLMEATFRRRNGFGHLSQESIEEKRRERRDAFKEARNETAVADSPKSPLSDDNGTPQSSGQADAAAVRRKGTLFGRRRDRRPTEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDS9</accession>
    <name>A0ABR3ZDS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="61368" checksum="C329C3FA328F9A20" modified="2025-10-08" version="1">MGLLDTATLVYLAVAGFLVLLMARLAQIGRRPSDLPPGPPTLPLLGNLHLMPTKDPHLQFQKWAQEYGPVYSLMLGAKTMVVLSSDVAVKEVLDRRSGIYSDRPDMFIGQTVASGGLRLVVMRYGDNWRMIHKMVHNILNIKAATTYVPYQDLENKILLEALLDEPKDLLLHIRRFTYSLSTQMIFGYRCVSNRDPNLLQLFHCFDKWGQVAGSASAQIADLYPILQKLPSWIAPNVSHARKLHVVERDLYVRHWMRAKRALDDGTGLPCFCNDIYRAQTEEKFTDAAAGYISGSLLEAGSDTTASTLYGFILALLLWPDVQTKLQAEIDAVVGPDRLPDISDFDSGKLPYVRCCIKESLRWMPTVVLGVPHAATRDDVYQGWRIPQGATVINNVWSIHMDEKRTPHPRIFDPDRFAGDKTSLYQSAIGDTTKRDNFVFGAGRRLCQGIHIAERSLFLGIARFSWAFTFTKTPGAVYNPEKLVGSITVQPEEFPCIVTPRSAAKAEMIRQAAAQDRTQLDPKTGQWRTVPAGMAFSTWMPDEKEAGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDV5</accession>
    <name>A0ABR3ZDV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Lysosomal cobalamin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="625"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="750"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="235"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="657"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="684"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="758"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="792" mass="88003" checksum="51A207C90438B5B6" modified="2025-10-08" version="1">MSLIARAAAALNVDVNDVDGDGAAASSAAFLASSLTSLEASNPVKSEIFVSIAMLIFALITLQILRYYLPLRSTPAYLIVPVFFALFLPANIVLLVPIDLASSAQTDDEATRGIWLPQTVLRVSWRITYWLTFVLTWFILPILAEYSDAGYRTPKDRILYSLRSNAQYHAMVFGSGIIGLAYVIVMYGFSVDSIKGLVMALAYVWGLILAIYLMGHGLVAIPRRLIRTATPSRRLRRLQSQAPKLYEKLEESEMDLEEIELQVVELGQRKTGSALDYREWIEELNEGVSLADSGSRSGGTGIASRTSAASADDRIVPTVITKKYMADLTRRLVRARHARSRYASEWSEHLQRYSETQAVLNSASQKKLELPKPKATDTLWDRVSILSPYQRYLVYYHIVPFSRMLFGVILALASACIVWSELVKAALPEASIIRITVVHHWTGDKGQVGFAGQLIATGWILYMCTAALTSITEVKVWRGRALVKRNTAHESAFWYASQVARLSVPLSYNFMTFLSSSIYNKTVFFNFLGRLITFTRLGTWFDYLLPTFILFPVLATLFGLYGRVRRFFGYGAEFGGVDDEEDDDYEGGNLRNYGTGSWREGRDLMERELNGTSIRQHRLEAAGRLGGGAEAGGRHGPVMVVPGGRRNAYEDDPEDILSSSEGANPTTPFAVSPSSSGILPAAPSARTRTLGAAGGASSSSGRRQNQHQQHQPFYDEEDEDDNIFQQLGHRMKNTMDTIEAPKWFQEIGQGFKKPKWMSGNNDEAGSSRNTPDSGNDNGIRRWFGGNDGRIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE15</accession>
    <name>A0ABR3ZE15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="4">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003317</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000997">
        <property type="entry name" value="Cholinesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00878">
        <property type="entry name" value="CHOLNESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044974900" description="Carboxylic ester hydrolase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="27"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="56808" checksum="3515FBE65CA2B716" modified="2025-10-08" version="1">MAKFAFTHLLAALAGMTFAAPAASSAATVITSSGQLQGQIASNTDGVSEYLGIPYAQPPVGSLRWAPPVAYNNSGVVDATAFGNTCPATTGVTSASQVQSNDYVTITEQGTDIIMAMLAQAEVTYSEDCLTLNVWTKPQTGEASKAVLVWIYGGGYTSGTTNTKAYNGKYLADTEDVIVITVNYRLGFFGFPGNPDGRTNLGLLDQRLAVEWVRDNIAAFGGDPDRITLFGQSAGGSSVDYYAYAWTEDPIVAGFICESGTVFTPGTPVSEAAATAKWTAIATELNCTSTVASEVTECMRAVGWQTVQDTSVAIGASSSGATGGVAGIASGFGPSVDNIVVYGNYAVQSVSGNLIKKPLLIGENNHEQGLFQVLLGLQNQSYSDATWDFLATSLFTCALSERALASLYNKIPTWRYRYFGNFPNLQLSTVPDSGAWHGIEIPTIFGTDLDIQNDVPRTAAQEEVAAYVRGMWIAFAKDPENGLTNYGLPQYNPLASTLLRPAYNNQTGPNAVNPALYDIGCVIDEPLLGVLELLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEC2</accession>
    <name>A0ABR3ZEC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003726</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="24"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="175"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="33986" checksum="42959F8F2B501F1E" modified="2025-10-08" version="1">MAPKKHRKTSSRPSHRSTLSLQKTEIVINVYDLLTPSRWSSLLWHMGTSLLHSGVVINGREYAYGGHDRRGVTGVYWTKPRTEPPGGTFRCEILQGFTLATTAEIDTIIRSASEEFYGPSYNLLTKNCNHFTAYLCRKLTGRPGPAWLNRAASIGLALPCVVPREWVDPPEFESADGELLRQGGSGSGGSGSSSDGGGYEDSYSEYGDDDYDDDDAHGERTSMLRRHSSSQHQVHLVGLDSPSASARNSMSGTRSTRASNEYHPEPFEEGDADVQTGRRSGSGSGSGGKGKGRPSMSRDSAGNALPPSERVPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEG5</accession>
    <name>A0ABR3ZEG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003212</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024789">
        <property type="entry name" value="APC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024790">
        <property type="entry name" value="APC4_long_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260">
        <property type="entry name" value="ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12896">
        <property type="entry name" value="ANAPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="7">
        <location>
            <begin position="29"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4 long" evidence="8">
        <location>
            <begin position="272"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="796"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="856" mass="93879" checksum="D7574B47D8E0C480" modified="2025-10-08" version="1">MAGAVERLKLFNQSVFIPPADSPNLVAACPTIDLTAAVGGANVVYIRRRGGELVSKVTERNKDVQALAWRSDGQFLAVAWNDGVVRLAGLESSKAVHQIRLYESSPVAITYISWAKNLVGSQEAWHSGLLESQDDQQSSALLDLPRALIFLEVEDDIPKLPPLPVSGGTGDDMFVFSTRTSLEFMFRPLKPKDGDSIHIMVLGTADGVIHVSIYDTFVMGTFKLPLPRNDGTPPSENGPLLHLRRHTSHPANSTHTLLLANEEKDSKAVYISHMDFAFIYSSPLNLSLLAYKTTTFQKLMRYIRQTADHMQVEWQSARDLPARFLANIQEDLQQQRKRKNIAHALRVAAMTGYVPAIVKEWLVDTIAERGYRRWDKAVVGGLQNLRDLIHENMMPALDRAMLALSRLRGLAEFHSNDDVGFSAGQITELMDIVSCLILVAHNSLSLVTAELELFMCFSTWLRSLIERLALPAQAEEQADKEPNLSITPVIDYISNHLLQSPLDLHFGKPAEGEWKADWKAIQEEPKNSTTTLLDQLEAEMERVDGFGVKPDILAILQDGLKENRDTKGKQASSKGPEGLNTHPDDPNEAAEEEADEDKVEPVKAFTKFGFLTRLFATQSDSVLKTIAESGRRHVHFGPLTRLSVGQTIKKAEVAMTAISKPDPEDSADALSFTTLSTKDDPKKIYIFRSAVATSEGVTTDVSTQGCVFEIGADGRVVDFQFLGSNLLLILWAATTDAESRLIVVPIQSPKITYGAYNGDGKDLPSVQLDNGLCWSAGVFAKGDNESLVVRMEVLGPRESGSEQAGDSNGSNSSTTSNGVMGDSSASTVRVCLMHADGKTHRVLSLPPTEEMFGSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFE0</accession>
    <name>A0ABR3ZFE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="15"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="441" mass="48410" checksum="AAFBF15BF746432C" modified="2025-10-08" version="1">MPSLVQQFRKMAASFEQVITKAVADRTIPGVVLLAENKLGTLHYEKVLGLSSLEPGKEKKLELDSVFMFMSMTKLITSVLVLQAVERGLWDLDADVAPLLPELAALPVLKGFDSDDNDNAKPELVARDAPLTLRLLLTHSSGVGYDFLTPNLMRYRSWLVKQPPEAGLEPPPKIVATPPSVEDRFRFPLSFQPGQGWTYGAGLDWAGRLLERLHAKVEGKTVPEAESKLPSIPLEEIVVRDILTPLGLPAGALTYHPERYPDVMARLWPSLPVRSGGPESPVVHGPSFYRKAPAAMGGQGMYGNMPSFMVFLRSLLHDDGKLLPSKSPISELLYAPQLPTDVARAQLLYNTENPGWITGDVPDTKEYDWSLGGLLVTGSSHPNRRKGAVYWSGAINLTWMLDREAGLAAVFASNFNPPGDPQGKALMRAWEAFIYPQAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFR7</accession>
    <name>A0ABR3ZFR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histone-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19473">
        <property type="entry name" value="SET_SUV39H_DIM5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="209"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="10">
        <location>
            <begin position="360"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="42040" checksum="A84AF3E407A57344" modified="2025-10-08" version="1">MGDRDSYREHFFNHNWKTGPPPQHVVDGCHWCQLRAFPTHQQYPVTIVNKTGDGATLPKNFKFITQSILTQGVRAADANFRSGCGCADARACRYDGCECLSDMLWDEEDQEPNSDDSDSEMETSRNGNRGGRPSAARAAGQKRAKFAYHSQGDKAGLLRSRYLDSREPIYECHEGCACAESTEGGVVAADGDVDDTACVNRVVERGRQIPLQIFRTEDRGWGVRTLVDLQKGQFVDRYLGEILTAREARRRRSLSTMARRKDVYLFALDKFSDTNSLDSRLAGPPLECDGEFRAGPTRFINHSCSPNLRIFARVGDHADKHIHDLAFFAVRDISAGDELTFDYVDGTVDLASDARHHVAGMTPCLCKSANCRKFLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFV1</accession>
    <name>A0ABR3ZFV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.13.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SAH1</name>
        <name evidence="7" type="ORF">Sste5346_002988</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.13.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.13.2.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004005">
        <property type="entry name" value="PRK05476.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-adenosyl-L-homocysteine hydrolase NAD binding" evidence="6">
        <location>
            <begin position="194"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="449" mass="49086" checksum="B89B6AA023201530" modified="2025-10-08" version="1">MAAPAGNFKVADISLAAFGRKEIDLAENEMPGLMATRAKYAADQPLKGARIAGCLHMTIQTAVLIETLTALGAEVTWTSCNIFSTQDHAAAAIAATGVPVFAWKGETEEEYQWCLEQQLVAFKDNKRLNLILDDGGDLTQLVHAKYPEQLKDCYGLSEETTTGVHHLYKMLKNGELLVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVAGYGDVGKGCAMALSGMGARVLVTEIDPINALQAAMAGFQVTTMDKAAAVGQIFVTTTGCRDILVGRHFEAMPNDAIVSNIGHFDVEIDVAWLKANAVEHVNIKPQVDRYTMKSGRKLILLAEGRLVNLGCATGHSSFVMSCSFTNQVLAQIALYKNKDEEFRKKYIEFAKTGAFEKQVYVLPKILDEEVAKLHLDHCNVELSKLTDVQAEYLSLPVEGPYKPDHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGG2</accession>
    <name>A0ABR3ZGG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase</fullName>
            <ecNumber evidence="9">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRI1</name>
        <name evidence="11" type="ORF">Sste5346_003067</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="529"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="599" mass="67265" checksum="B1DB6F7E35517938" modified="2025-10-08" version="1">MPHAVSDPPSPAQEDAAMADASSPNTVEAESTPTTSNANIETNAETSNEEAVPVKVEQASSPPWVAEDDDDDEMAEEATALAAAPAVTIKTEDGSVKDVLAATAAVKTEEAPASGSIAVKTEETEKAAIITDTVPVNLEDMFDDMDDDDEFSGKPAQETLTTTSDLLSLKASDPEVMRSFYQRLFPWRYLFQWLNHSPTPTNDFAHREFAFTLQNDAYLRYQSFPTSDLLRKDVLRLMPSRFEIGPVYTTNPAERKTLSNASAFKALAKELCFDIDLTDYDDIRTCCDKTTICMRCWQFITMAVRVVDAALRDDFGFQHIIWIYSGRRGAHAWVCDKRARSLDDQKRRAIVGYLEVLRGGSQGGKRVNVRRPLHPHISRSLNVLRTHFQEDVLRDQDPWDTPERAEKLLNLITDRNLADALRRKWDSSPGRSSTAKWADIDAVAKTGSVKGLDLKHLLENKQDIVLEYTYPRLDVNVSKKLNHLLKSPFVVHPGTGRVCVPIDVNRLEEFDPLGVPTVQELLQEIDSYSQNSGANGSDDEPSQNKNGAGGDEKKLQDWEKTSLRRYIEQFRSFVLNLMKDEKDVIRVKRERDEATSMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGJ3</accession>
    <name>A0ABR3ZGJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100">
        <property type="entry name" value="IMP2'P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100:SF4">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="527"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="650"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="777" mass="84048" checksum="038004D859FCEC23" modified="2025-10-08" version="1">MSHKPMSMEAVMDEERREVLALLEGRSDHSRRSSSIASAGRSASPYSRNPRSPMRSPMQSILDYDDLEVPPETSNAFNAGASNTSRQSSPRPAAQPIRSMLDIDPVRPAPAPIRSMLDVDSPPMATVQPVFSAQSSPTEPNHRVHPPASHHRHSSSGGSGGVHHPRSMSDAAGHPVSFGPRAHQGRTDRSDPTAGYQFSDIITNRESPMMAKRSGLSSSHTASSSKRGSSMAEVMRGTDMGNLKLPGHTLPLHGRNSVSGARPKAPTNKSQSPHNRLGVRTKSPHAALNNRALSPAGAAFLADSKSYDMQNAYRRLSDFNIRRSGGGSLSELPMRGTSANGTGRLAKDYMSPDGEELPEDSSEDNHSSSSDEEGERGRKTARSFTDEKSPQPSESPVDSRKAGHQSQSLLAAAEEERIHVASTQPYRSLLEPEIVVTNSSGDKVKPTKAGVHPANSFDVPSRSESRTPWDSDDEAEYTDIKRAQKLSLSMTPIMSTPAIQRSIRIIYRGEFAKVQKEAADDEHRRVRKYLVATDLSDESTHALEWAIGTVLRDGDTLVAIYCVDEETGIPGGGEAQDEPKTTREQAQAISATTATGRLPETYSLSALATATASSAALSVAAPPASSRPSLILRNSDGSARGVGASASPAPQRSRAEEERHRAVQDITDRISRLLRKTRLQVRVIVEVLHCKTPRHLLTEVIDLVDPTLVILGSRGRSALKGVILGSFSNYLVTKSSVPVMVARKRLRKQSKYKRPPFHQVNNLSNPTARSLANAKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGX9</accession>
    <name>A0ABR3ZGX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF80">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="76"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="270"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="367" mass="37965" checksum="76C243424F29601F" modified="2025-10-08" version="1">MTADDLATRAPESDAAEDASPAPAAAAAASSAAEPAATGTATPKLCDDCVTDRPLPSGPNGSRTPAGEIRKLDDVNTYVAKPSGYPHAPARLLLLLTGGTGMQSTNNQIQADMYADEGFVVVMPDLFGGDVAPNTAAAEEEAVATNDTGSFLDLFKTKAVETVKSFMIDMWLARHTEAKVLPLLHRVISAARDEFADAVARGDGIFAVGYCFGGRYVLLLAGEKASQYDAEGPVNAAAAAGATASGSEANNANSDAAASALEAGLLSKPAPLIKAGVLAHATLVSPDDFQGLQAPISMVCVESDPLFPDEVRTAGEDYLSQNNVEHEVQVYPGVPHGFAVVGDYADASIKDAQATAFEQMLKWLNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH84</accession>
    <name>A0ABR3ZH84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002954</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="4">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0041">Annexin</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="456" mass="50444" checksum="33E9EC1F74898157" modified="2025-10-08" version="1">MSYYPPYGQAPPPQGGGYYQQAPPGQYPPPQQGGYPPQQYGAPPPQQAPYGAPPPGQYGGYSPQPPAPYGQHPPPPPQQAPYGQQPPYGQQPPYGQQPPYGQPPQGPPPPAGYGPPGGGYGGGGGGYAANVPPTPPSIGYAGAQPINWDATHDANALRQAMKGFGTDEKALIRVLADKDPLQVDAIRNTYHRLHRRDLIKDIESETSSWFEYGLVALSRGPLLNDVHMLHDAMSGPGTKESVLNDVLLSRSNADLRAIKALYQQTYHRSLEDAVRGDLSMKTERHFMIVLQATRAEDAAPVQKHEVDRDVQELYNATEAKMGTDEIRVCSILSTRNDNHLRAVAFEYRQRYARALEDVIRKEFSGHMEEALLFQLRHATDKYMHQAALLEDAMVGAGTRDKLLVSRIVRIHWDRTNLANVRGAYEKRYRHNLAQRIRGETSGDYERLMLACIGERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH95</accession>
    <name>A0ABR3ZH95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="295" mass="33259" checksum="863B8DBDE8979C93" modified="2025-10-08" version="1">MRSGSGRACTSIVTEYHPKQPGQDAPFLIEVEYLNKEEMKEHLKELLWNYRRVYLPDINAAALGDAEYQQLEAASNTAWFTLQTAFRHENAFSATFAKDMSDGADDRILDQLIAWSDQIEWPQGSESGYWTTTEVTADACTEATRPFMEDKFWPFTKIIRVYLSSRVLDAGIVLADLPGLRDVNLARVRATQQYISRCDSILIVGRISRAISDQSLQSSLFMSLASQAPTEWQENGGAKFNIAVVCTHAEDIHMQTERRKLKDAAIESELTRLDGGIQSARDAGNLREELSKRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHI9</accession>
    <name>A0ABR3ZHI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="260"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="820" mass="86454" checksum="E7AAAE58BCBF9C86" modified="2025-10-08" version="1">MDSKMAASSPQLPASSAASTDSGEKGAAAAAAAPTRTPSWLSRFFATRRKTKMAAIIFVALGIVAIAVAVPVTEHAKASHKHNAVITSASGATLLVDNDLSGGVTNRAALLMLSPRTYAAAEADCKALGEELWGSTNSSSAAVDSIQSLLDYLTYMNQASSTSRFWIAAAEDATSTGGTVSSSSWRTVDASGNIAAFNSTKAVDTTDLTLSALCTQTAPYSNHTSINNDPVYGVSVSASIDHPDNGANGVAQVVGHRDHNSFRFLGIRYAPQPKRFTYSTPYWNRTTSSLFNNTSPNNDTVLPIVNATKSGSACAQSGGVGSEDCLYLNVFTPYLPAPQQGSLTSPASSAGVAPALRPVMFWMHGGGLTGGTGSDPTNDGGNLASRGDVVVVTINYRLSTLGYLALDSEHGGLNGNYGLSDQILALDWVRDNIAAFGGDPERITILGQSAGAGSVRAMMASPLALGKFAAALPMSNLGGLNYGKSYSEYYTIAQEQTVVGNAVLTATNCTTGGANSTTANSTAEAIVDCLRAVPARQLVALSSVARFIVVDGTYILSDHLQLGTVNTTVNNTAAPYKLMMGTMRDDGAPFIDFPSKQASISDAAAAESTYLSSQGYHNISADLFPIPNTGLNATLDLYNMSSRLSTDAVFRCVDEATVYAGLQTGIFDAAYYYEFDRSYQTTGWPGTNICAPNATEAHPFGDPSLPYFRCHSGELYYVFGNLARQGLPFRDEGDQPFSQYVLDSFAAFARTYSPNPDADFLKARGFTNTSDIIKASSSWTASTKAKGVSVHLLDWPESSQSEFREQPQCESLGLGLNYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHQ7</accession>
    <name>A0ABR3ZHQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044980">
        <property type="entry name" value="NDUFB2_plant/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="51" mass="6045" checksum="67C929E40898B21E" modified="2025-10-08" version="1">MNFHNKPPVPHVPFVYRFTATALGASMWFFLMYRAKKDGPALMGWKHPWEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIL5</accession>
    <name>A0ABR3ZIL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="257" mass="26226" checksum="60EE47C8D22AB2FA" modified="2025-10-08" version="1">MLAKKDFRQAIGGLLAICIVVFYILVLVGCISTSPGLPGIYLVKLANNATKAEVHVGLFGLCAGTDPVNLTCSGTVAQSVAVNASSASTKFFLPGTSTVAPSSLQPMLALAAGIQSGSTGPGGVLSIVYIPLFLSSLCFVGAAGSLLTHRIASRGVQSDEYADEKGYGHTRNAWNAAVMLTTGAVMAALAAAISSTVAVRALLFAGTSLPGGDSASSTSASAINVSGGTSIQVLEWLIVVLTMLWHPLLETVWRKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF1</accession>
    <name>A0ABR3ZJF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">DNA polymerase epsilon catalytic subunit</fullName>
            <ecNumber evidence="18">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">POL2</name>
        <name evidence="21" type="ORF">Sste5346_002242</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">DNA polymerase II participates in chromosomal DNA replication.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 18">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="18"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05779">
        <property type="entry name" value="DNA_polB_epsilon_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05535">
        <property type="entry name" value="POLBc_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013697">
        <property type="entry name" value="DNA_pol_e_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029703">
        <property type="entry name" value="POL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055191">
        <property type="entry name" value="POL2_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054475">
        <property type="entry name" value="Znf-DPOE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08490">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22634">
        <property type="entry name" value="POL2_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22912">
        <property type="entry name" value="zf-DPOE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23250">
        <property type="entry name" value="zf_DPOE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01159">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 18" id="KW-0235">DNA replication</keyword>
    <keyword evidence="14 18" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 18" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12 18" id="KW-0408">Iron</keyword>
    <keyword evidence="13 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 18 21" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 18 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 18" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase epsilon catalytic subunit A C-terminal" evidence="20">
        <location>
            <begin position="1630"/>
            <end position="2025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1289"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="2087"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU365029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM01159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1900519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2367" mass="266997" checksum="6D74B56E1BE8C91E" modified="2025-10-08" version="1">MPNTTLRRQPQKGFRKGGQKKAYHGGAQQRTFAAGGGRNEGTSADEKWERTRLAHAIDEKMGFPRYEGSRRREGWLVNVEPTSIEDDRVEGGGGRSAVDLYFIDLHPDGNEASAPDADATTFKATIEYEPYFLIAVRKGHETEVEEWCKRVPGGGGLVKRVRRIDKEDLQMPNHLLGYRRTFLELRFDNVQNLLAVRRDIMPIAEANKKGMNAMDTYAEVAGASTVLGDGDNDDYGHDLFDDDSRNAHADDQARRTNTSVAEASDYIVDIREYDVPYHVRVLIDMDIRVAKWYNVDVKHGVTTVTCNEERLAMADPVVMAFDIETTKSPLKFPDATIDQVMMISYMIDGQGFLITHREIVSEDIADFEYTPRPEYPGPFMIFNEPDEKALLERFFLHVKMSRPTVIATYNGDFFDWPFVEARASANGIDMYHEIGWRRDSEEQYKCDYSVHMDCFHWVNRDSYLPQGSRGLKAVTVAKLGYDPDELDPELMLPYAQERPQTLAEYSVSDAVATYYLYMKYVHPFIFSLCTILPLRPDEVLRKGTGTLCEMLLMVQAYQKEIVLPNKHVSPKESFWEGHLLDAETYVGGHVESIEAGVFRADIPVNFAVDPTACDELINDLDAALEFSITVEEKKSMDDVTNYDEVKAQIIAQLQSLKETPNRSERPLIYHLDVASMYPNIMTTNRLQPDSMIKEEDCATCDFNRPGKTCDRRMPWSWRGEYIPAKRDEYNMIRHALENERFPGKGAYAAQKTRSFQELSADEQAGLIRKRLQLYSQKVYHKIHDSKTITREAIICQRENPFYINTVRDFRDRRYDYKGRAKVWKGKTESLKSSGAAASEIDNAKKMIVLFDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGVTCLTGAHIIQMARELVERLGRPLELDTDGIWCMLPATFPENFAFKLKNGKKMTISYPCVMLNHLVHARFTNHQYQTLVDEKTFRYETHSDNSIFFEVDGPYKAMVLPTSKEEDKNLKKRYAVFNDDGSLAELKGFEVKRRGELKLIKIFQQQIFKFFLDGTTLAECYASVAKVANRWLDVLHSKGATLADEELMELISENRSMSKTLEEYGTQKSTSITTARRLADFLGEGMVKDKGLNCKFIICARPRNAPVTERAIPVAIFSADEATKRMYLKKWLKEEPQDTDPRALLDWDYYLERLGSVIQKLITIPAALQKVRNPVPRVAHPDWLQRRINIKDDKMKQKKLTDLFGKQSGPLEDITGNNMRVNGGSAAADMEDFGSLSASQKLIKPTTTAGAVAEMISIEEGAETDRASSPSAAQKRKSPPEHEDSASLDPFAALPKVAPSASEDYAAFLEYQKKKWAIQKQARIRRRHLFGDRAGGGNGGGGMMQQKANNIQQSFQHRAEITFRNNWQLLQLKTTDSPGIVAAYVLIDARIHHLKIKVPRQVFLNLKSKDLPDIEIPGCEVEQVNHTLPNGHSSVYLFKLTVSEEVYFAEAEKFALLFNHPSVEGVYERQLPLNVRALLQLGNRCTIDQSQQGVLGKGLDQGFDLTGLIRPAKTLKPYLDPSSMAYIHLSHISSGERQIFGLFSTTNSQAHIVILHRNRDSVQDMPNVGKLYGDMLGRRRDAEAEAKAGATPAALAALSSNAEKEAAQQAAAAASTWRDCFPYQDALTVKVTQITTRRKAFLEIGDIVKKMRKEEIGRPQILVVQSSQRNMLVHDIPVLGEFPVLPLKYDPLDSSLPPLGWQSVVARRLVSHYLALGAWVMHLVGLARYGDVPVCNLERDDPRFLIDVAYARRLQANNVVLWWSGSPRPDHAGYEKDDVAGPLETVQLPKINNPGTYASVCIDIDVRNLAINTILTSSLINELEGADAAVSFNPAADAGGAFGDDADGGTSSLYAENAFSNASILVLREMVKGWWAEACKGNAMADLVVNNLVRWVENPDSFLYDRALHYYVQMMSRKAFQQLMADFRRVGSQVIFASANRLLLQTTKAEVTNAYAYSQYIIKSIKNRPLFSFIEMDIKEYWDYLVWYDEYNYGGKACQTIGGGELVTLPDGTQAEAEQPLETIMHWQMNTFLPVRLQPVFSGWVVEFVQLMHGLKRPESVHGSSQPRLTQLPPAVLRNGNGDAEGKALLGPSFERPLKKEIAGLISTRNREMLHPELASDYDYPVLPGTLVMPAVNKDAKSSKKVAAAVASRDPILELVKALMQVLSLDKNITMEARLLRKELLALFDVREFSRDAAFQNPSESLKLSQISCDNCTTSRDLDLCRDEDLLPDQQGGAAKPWVCTFCQAEYDRIALEERLVAAVEAEALAWSVQDLKCGRCGSLRVNDFMDHCTCSGEWGPTVRRDEVVRRLRVYRNVATFYGLRMLSDVVEEVMGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJK3</accession>
    <name>A0ABR3ZJK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine arginine repetitive matrix protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="726" mass="77800" checksum="4334B07F36005FF9" modified="2025-10-08" version="1">MDRDRNNNRRFDDGEVTRYGAGESWRPSARERSPRRDRSPIRDRERMRDWDRDGGRDGGRDGRDGPDRRDGRDGRDGRDGRDGRDNIRDNIRDRRVSPPPPSSDSYIPGRSPRRPRSRSIDRYRTLERDRDRDRGSERWRPVERSRSRPRSPGGLGGGMGGMRGSGGVGGNGGGAGNNDLRRSPPRRMSPRYVGSPRRGGGAVGGDDRGGRMLDRDRGRSPPPRRDGPPPLRDIRRRSRSPPDRGPRNRSHGRRSPPRFRPRSRSPDRADRPLGDDRMGGPGPLRRLPSPTRERDFGNFSNQPLSAVGSRAGSRPNSPRRSPAGRQRNDRSRQASQTPRSPHIGGPVGGTSINATPLGSSYSAGGAGRDRDRDGYFDSPSNLHSQFATPSVRSPPSGPASLRPPQDRPGQGRKMGPSPGPSTPLAGRPAQQGQGRGELSPLSTSGPPTGPRGYGQGRPGGAAADRSGSISGNGGGGLGGPNGPFTPRQGGRGNGPWGLSGGPGRRMSSAGPSPSTGGPNGEDGNGGRGRGGIPTGPRGGGLGGPSGSSANGPDRPNGRRSRGGSPSFGGGSRPFNPPTGPASQQQGQQQSSGGAMNGERNSYHRDPRDRDPRDRDRSGRGSLAMSSSAPTVAQQAMANMPVIIPGGKLDPLLHTGILPEMLPHYQRLREEEERLRAELDVKQDRLRKQLRLWDKMEREARAFELKSELSEKSLKTIAGEGMGGAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK69</accession>
    <name>A0ABR3ZK69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Omega-6 fatty acid desaturase (Delta-12 desaturase)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021863">
        <property type="entry name" value="FAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11960">
        <property type="entry name" value="DUF3474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="8">
        <location>
            <begin position="95"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="46210" checksum="36EDACD33740A5DF" modified="2025-10-08" version="1">MSAVSSSVSSRQPSRRASPVGTKEKADTFVAVNAPQEFPDIKTIRDAIPAHCFESSTLHSMAYVVRDYAMAFALGWAALAYIPGIENTLLRTGAWITYGYAQGLVLTGVWILGHEAGHGAFSPHGVLNDVVGWVLHSSLMVPYFSWKYSHHRHHRFTGHMEKDMVFVPRTTPTSEMKPSFATLWLDPELVEDAPLAQVLQLIAHQVAGWQMYLLFNLSAGNDSKQRENAPWYRLSHFEPTSAVFRPSEAVFIALSDLGLILMGSVLYFASTYVGWSTVFLMYIVPYMWVHHWLIAITYLHHNHPEVHHYDAESWTYVKGALATVDRDFSWVGRFLFHNIIDTHVVHHLFPRIPFYKQEEATAAIRPLLGNLLHKETRSFMGQLWSTWKTCKYVVPDPNVPGAMKWAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK96</accession>
    <name>A0ABR3ZK96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002377</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF181">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="495"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="61"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="58371" checksum="8127335EDA8C69EE" modified="2025-10-08" version="1">MHLHTLRELDRTDGTVQLRQVHHHDASSPDSSTTDLVLIPRPSPNDPNDPLRWAPWKKHVAFGSVCAFTFLTNYAIGGLAPAFYTLSLEFDKTMTETSTLLLWPILVLGVFNYIWVPVANYIGKRPVFVFASGLLFATYIWGAQATTFDSLLWSNIVGALAGSSTEALGASIVNDVYFLHERGAKMGIYMNSISGGNTIGPLVCGFLVTSLSWRWHKWIAAILTFINFLAVVFFVPETRYIRDADQNVGVVGGAEGTAVTVNGGGSGREKTTDPVIVPTTTASSTSSEIPKKTWLQEINPWSGITPGTSLLGMFARPFPMFAYPCVVFAFFAYAVALVLTCAVNILNSFVLQAPPYNWAPSMNGLINIPGLIGNLIGGWAGGSLVDHFCDWWLRRHGGVFEPESRLYLLALPTVITGAGCLLFGFGVQQTLHWTSLFFGYGMVSFSLTAVPTITMAYVSDCLLPVNADALMLVNGTKNVVAFGFLYGIVPWVTDVGYAACFGAQAGIFVAIIAIGALLLLRYGAAIRHRQAQWRIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKY5</accession>
    <name>A0ABR3ZKY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein tsr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TSR1</name>
        <name evidence="7" type="ORF">Sste5346_001953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22298">
        <property type="entry name" value="Tsr1_G-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="6">
        <location>
            <begin position="80"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="839" mass="92931" checksum="C94F907C4628AFC9" modified="2025-10-08" version="1">MSSTMAGHSHKSTTKVAHKPFKAAGKGRRHKGKTADERPRTPHQQVMSKLDRRNQNRQRQLEKQKEHRLEASIFSGRDAAPRNVAVIPLCVDCDAAAAVQALSSSLDIETAVGSNGGAFRVPVERFKQQLQYILVPGDRDVLASIDAARAADFVIFLISANEEVDERGELILRSVESQGLSTLFTAVHGLNSLDSAKQRTGTLDSLKSFMRHFHPDQEKLFALDNRQDCSNLIRSLCSATPKGIHWRDERSWILVEDVRLGASGDDAAAVLTGVVRGRGLKADRLVQVGDWGTFQIDKITAAPLETRKPKGAAADSMVVDGQDGSEEGVLDVPSEDRDDLDQLAPEGAVLSDSEDDEMEADDLDGRSVAAASRKGVLLDDHHYFSEEEDVKTMPARRLPKGTSDYQSAWILDDATSESGSDMDDEEDEAMGVDGEDGEEKAHPADGMEGVAQYAATEGGAGPSEYPQSEAYVERDDEQEAEQLALYRQQKRSEAEDDLEFPDEIELHPNVLAHERLARYRGLKSLRSSRWNEKEDRPHEPVDWRRLLRIPDYRASRIRSTREALIGGVAPGTRVSVHLAKGVLPVEVRAAYSPSKPVTLFSLFRHENKQTVVNFLINLSAEEPKSIKSKEEIIVQCGPRRFVVNPLYSQSGVTPNDVHKFARFLHPGQSAVASFVGPVTWGSVPTLFFKRVKTSTVPLLPGVSVPPNMRLAGTGTSLPPSTSRVVAKRVVLTGHPYHIHKRIVTIRYMFFNREDVEWFKALPLWTKRGRSGYIKEPLGTHGYFKATFDGRINPQDSVGVSLYKRVWPRKAKPFQEWAPATVVEESAQAGGDDEMDEDMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL43</accession>
    <name>A0ABR3ZL43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="360" mass="39253" checksum="6F9401DA9859E9E3" modified="2025-10-08" version="1">MSHTLGEDPALDAETRVPILIGTAVAFSVATSLVVLLRMYTRHAIVHAPGVDDYTMLVAAVLAVGVTISTILQAQNGLGRHVWLVSDAETMVQLKSLFAGEVLYNLAQICTKISFLLQYRRIFRDEHTRTVCFWLILFLALWGITQEFLVAFACIPVSVFIPGMASKCIESLVVWYLTSIMNIVTDFVLFLVPLPAIRNLRLPLRQKVLVMSIFCLGIFTCIISIVRLFTLRAALNSTDATWDNAPTSWWTTIELNCGILCASIATLRPLIRTLTGRPVTTVGAGTAGTAESGTSRARSSFRKGAYPLHNLPSGNESQSGLNFKEDAVNDGSSRGSNGGSTTNGTSYEYAEARHTKGDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLF5</accession>
    <name>A0ABR3ZLF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptide transporter ptr2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PTR2_1</name>
        <name evidence="8" type="ORF">Sste5346_002113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="554"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="640" mass="69467" checksum="FFC26E3F4D4465EE" modified="2025-10-08" version="1">MDADIEAVAAGPTKDHGVAQVLSGVAPIESEQVGTVESAAVEHAHETPAAPPPYTGDNKEPPAEEKREHTAQDFLPQGSAEYPVPTEEEQRTLRRVAGSIPIAAYVLCVAELAERASYFGASTVFSNFMEFPLPEGGNGSGAVPKGHPEDHAGALGMGLQFASAFSLLFTFLAYVFPILGAWIADVKIGRFKTIMLGVIIGGVAHIIMIGGAAPAILRAGHGVAPFVISLLMLSTGAGIFKPNVAPLLIDQYQHQHDYVKTLPSGEKQIVDPERTIQRILLIFYAMINIGSFFAIATTYTEKYIGFWISFLLPGIVYFLLPILLLIIRKRLVQRQRGSGGSGSELANFLKIAFTAVRRNKGAIWRKDFWDAAKPETLAARGIRVSWTDRAVVDVQRTFEACVVFLYFPLYNINDGGVGSLSNNQGAAMTSKGAPNDLLTNLNPVIIIGVTPILTYGFYPLLSHFNIRFGPIKRMTFGFLLAAISGVFGAIVQWKVYKTSPCGYQASTCPEGMVSPISIWWQVPNVAFGAISELFCNVTAYEMAYVRAPPQLKSVVMAMFLFTNALSSAIGEILIPAIIDPHLIWVWAGPAIALFAQTAIFYFRHRHIDDEIYLLEQNLAGAPLGAPHQATLAEPETEKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH1</accession>
    <name>A0ABR3ZLH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PUT1</name>
        <name evidence="7" type="ORF">Sste5346_002154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF30">
        <property type="entry name" value="PROLINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="113"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="459" mass="49797" checksum="965B3F8611A839F9" modified="2025-10-08" version="1">MPANQFVALDNGSTVFDAATSAAASTVAAPASTTASKPSALSVLPLSSVLRSLMTTTVSSSPLLLGPSMAIMTALAHSANPFLNPDRNILLRYLLKKTFYAQFCAGENEREVRQTIDGLKTIGFRGVILGYAKEVVLKDEEKKNLATFDGSARKEATASEIKAWAEGTLETVRLTAAGDFVALKFSGAGIQALHDLSEQLPPSPALADAIDRICQLAVERKVRLLFDAEQQAVQAGIDDWTMAYMRKYNTAQKAFIYGTYQGYLKATGAILSQHLRMAREGGFALGVKLVRGAYLGSDPRHLIHDTKEDTDRAYDGMTTGLLQREWTFPLVAETPNEAFPVVGLVVASHNAESVVHAQSLLASGACKTSDVAFGQLQGMADEISCKLVLDDKTCQAQPDNKVAPIQAYKYLVWGSTGECMKYLLRRAHENRDAVQRTKSSRDAMMAELVRRFKGVFSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLS4</accession>
    <name>A0ABR3ZLS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="126" mass="14465" checksum="6B7C020556E9A31F" modified="2025-10-08" version="1">MQEIIAGVEADTTQLKFELSSVKAILRSKGNLHRLWLCFWTALILTATYLKIGEKFFINPIGIQILSWRYYIFQCVFNALLTTIIYFTYAETSGLTIEEIAGIFCGEEQFQNALARPELEKMGVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMA0</accession>
    <name>A0ABR3ZMA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavin-binding monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001528</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="64868" checksum="EF6010A6545666E9" modified="2025-10-08" version="1">MADFTLKDANVENLRPLKVRVIGAGYSGIVAAIRISQKLRNVDLVVYEKEEGIGGVWWVNRYPGIACDIPAHSYQYTFNPNPHWSSLYAPGKEIQAYLQSTAEKFGATRFIKTQHKLTSAAWDAATKEWVLQVTNLATGESFEERCNILITARGQLSNINWPDIKGLDTFKGKIMHSAAWDEDYDFTDKRVAVIGNGSSSIQIVPSLQKVKGTDLKVFMRSKTWISSRFGDNAMVQMGLDPNDVDFPPERRAEWAADKDAYFKLRKAFETDGNAIHDSTIMGTEMQKLFQGIFRGGMQERLKNRPDIFDLIVPDFAPGCRRLTPGKGYLEALMEPNVEVLAEAAGGVDETGVITGSGRHLDVDVIVCATGFKVSEPPPFPVRGRDGLELEARWADKPESYLSVAVDGFPNYLMMFGPNSAIGFGSLTKILEAECDYIVQVLRKVQREDYATIEPKKERVDDFSQYIGAYFKNTVYMDKCRSWYRTQGGTGDWICGLWPGSTVHALETLRSPRWEDFDYTSVDGDKANFMRWLGNGRSETQEPGGDPSYYINPEFVDMPLEGRPEDEPEFKVRPWLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMF9</accession>
    <name>A0ABR3ZMF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001601</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF5">
        <property type="entry name" value="BOX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="223"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="30967" checksum="901BDEC432539355" modified="2025-10-08" version="1">MARPSKKQQAEAAKADAPKQIDVENFIRVRDSVYSRLSAIQDLLKQFSIEYLRQTNLLLGEGAGVDGIGELIGGFDAGLLPQVGAVLPPVAVVAAPAADEKKERKKRTHDPNAPKRPLTPYFLYMQTARPIIANDLGPDAPKGAVQEEGQRRWSTMNAHDKGGWDRAYQYNLRLYNARVHSYKSGNANARLMPDEDALRYADEFHIPMPTSKEADTGNDQDAIAEQLQQGPADDAATKTPKSAKKDSRKRKTATPGAEAEPVKGAAPASPDKKRKRTSKVTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMP4</accession>
    <name>A0ABR3ZMP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-galactopyranose mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF4">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="57079" checksum="879A61F08439933A" modified="2025-10-08" version="1">MADINVDVLVVGAGPTGLGAAKRLNHINGPSWLIVDANEKAGGLASTDVTPEGFLYDVGGHVIFSHYKYFDDCLDEALPKKDDWYTHQRISYVRYKELWVPYPFQNNISVLPKEDQVKCIDGLIDAALECRVANTKPANFDEWILRMTGKGVADCFMRPYNYKVWAVPTTKMQCQWLGERVAAPDVKNTIRNVVLNKVAGNWGPNATFRFPARDGTGGIWIAVAETLPKEKKVFGKKGEVTKVDADKKIVTLGDGTTVGYGKLVNTMAVDKLVEKMEDKELVDLSKGLFYSSTHVIGVGLRGERPERIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPEADVKLPTLYHADGSKPASSEPEAGPYWSVMLEVSQSELKPVDEENLLKDCIQGLINTDMIKSADEIVSTYHRKFVQGYPTPTLEREGVLKELLPKLQAKDILSRGRFGSWRYEVGNQDHSFMLGVEAVDHIVNGAVELTLNYPDFVNSRQNTERRLDQTFAFGAQATLPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMZ4</accession>
    <name>A0ABR3ZMZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RFC checkpoint protein Rad17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rad17_1</name>
        <name evidence="2" type="ORF">Sste5346_001542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="190" mass="21723" checksum="B5C56727E4FE57FB" modified="2025-10-08" version="1">MASHDTKTAKRTTTTTYWTRRYVFACNHTTDRYYPVKDATTDGQFKVKRVPLLLPVRLGRDCSACLRREIFERVHAKANDVRFTFNSLCAKLDRPKTTGDGLDEPLLVDEDAGADDEVWPEAPPSLESLSRLYMTKVASFETESDAGSEFTVKAKTATSPAVRHEKLSDQIRSIREDLEHRRQAWESRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN04</accession>
    <name>A0ABR3ZN04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">28S ribosomal protein S5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRPS5</name>
        <name evidence="8" type="ORF">Sste5346_001856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="312"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="52911" checksum="AD2D70E09B450EED" modified="2025-10-08" version="1">MSFARTTAGGALRRLAGGPEARRCTAAMATTQSKAPLPSPQTPSSSTFSSPSPFFIQASSFHTSAPRPARRRPRFSNVSAVEMGLVDDTSISKFAKKHLPDYTEAEKQLLSEKYTPAQMAAVQAGEEAVSQTDIVKQGRFRNIDEATQAGINYFDDFSKVQPIIDHRFKDPNLAKQVPARFTTMEDDRFTDDLEEWLKGFIPEGEDIQWDQLSLKQRAELADKYAPSDMDVFKYLYNRPALVHGKDQARVLPEELGNSSLALGTRHNIPGMSDEYTRSVMQPDPDDEGLDEAGNYKELTARTGLKVSEIFNLATKEIVVRMVSNQTRLGKVRSYSVIAMAGNGNGRLGLGSFKSTEFTIARSRAREAAVRNMRPIPRYEKRTIYGNVEHKISGTVVRLFSRPPGFGLRVPHHIFEMARAAGIQDLAAKIPRSRNPMNVVKATYAALMNQRDPEQIAIGRGKKLVDVRKVYFGGAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN49</accession>
    <name>A0ABR3ZN49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">threonine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MST1</name>
        <name evidence="12" type="ORF">Sste5346_001604</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF50">
        <property type="entry name" value="THREONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="112"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="566" mass="61843" checksum="18083E3079135524" modified="2025-10-08" version="1">MLSPRHASAALRAPAARLALTTSPRPSSSSISPISSISSPRFSLITPSIRGHRLLLSLSRQYCSSHGSPAQSPPPKQVADKDRIPPDHRDLAVQQELFTTSIYSPGSPIFLPNGARIFNRLVDFLRKQYVRYGFQEVITPTIYKKALWAKSGHLDNYADDMFTVSSASLKTGEKRVDSAQATDETTAATIEDEYGLKPMNCPGHCLIFAAQRHSYRDLPIRYADFSPLHRDEISGALSGLTRVRRFHQDDGHIFCRPSQVEDEIRSTLDFVRFTYSVLGLGPYRLVLSTRPTDGHLIGSEADWDAAEDALRRALDSSGQAWTINPGDGAFYGPKIDIILQDSDGKEHQTATVQLDFQLPRRFELSYQAPSPELEREGRAGEVEEGSADATEAGPVTPVMIHRAVLGSVERLMALLIEHYNGRWPFWLNPRQAIVLTVNDSDAVVSFAKEVQAVLAGTSTSTLTSTESGPITSSPTLLAAVDVDTSARTLPLKVREAKSKGYGAILVVGPKDVAKGTVAVDLSGIPVKGAEEVTEAPTSGKKRKQPTVEMTPEALLKLLQEKANTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPU7</accession>
    <name>A0ABR3ZPU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Csi2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051009">
        <property type="entry name" value="PRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36089">
        <property type="entry name" value="CHITIN SYNTHASE 3 COMPLEX PROTEIN CSI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36089:SF1">
        <property type="entry name" value="CHITIN SYNTHASE 3 COMPLEX PROTEIN CSI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499555" description="Csi2 protein" evidence="3">
        <location>
            <begin position="30"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="40788" checksum="80C215373E60676B" modified="2025-10-08" version="1">MSRSRVSLKRTLLFSAVIAVSLLSATAMAADSTTPAKTTNTPATQKTATTSPKAATSAADSSTPAASTPAKSTAKTTAKDSDSAEPASSTPKTDTTSAKGTTVITPTGSQQSSETASVPALTSETGTTSKLNLPTLTTTNTGVPTYPAPTVPPTQNAPFMQHSNLPDGTVFIAVGAILGGFAAALLVWRAVVAYLLHRSIARAAQAQHAANDKAPFASAPAAPFYKYSDRESSLNVGAAGAGSVAGSARGVRRTNRGPIPSATPSQTNLFFSPTAPGASGMGAGSNRDSRLLPSGFYAAGSASPAGAAQGQAINMSNLRPDSRHGRNVGPSPPDSPNFGPMRTNLAGRNMSGSSVSLNRPASGRAPSAFLDDLLDDQPHLFPPGTGPSHNHTYSQSSHGGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ36</accession>
    <name>A0ABR3ZQ36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="506"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="59907" checksum="31C7469536967749" modified="2025-10-08" version="1">MSPRVQYYVVRPGPVTMLPSGGRSQAPARLVPLVAIDQLPDWVDIVGVPRELKPEEAATMLAISSDDNSFDTKVKIKDDDGDIDSNSNVFEVRIISQKNKATPGTVTSPKGKYKTATVVKEEEAASNETKDTEDTKDAKEAPVFVTAPSTPAGVTIAAPTTTPTMLAAREFLSKDKGANGGAPSEIDYDFLVAFGQSPSEHLLNSAAEAKTVTDAVKTKPTANGNNYTLVNDLINFGVTDSQPAMVQLDGAVDGTHLEKEAKQTGAKTDAKVSVTSTSASGDKKEKKEPTTPPPKPGSPLKKTVVAKLSWSPQKPRILTPGKPCRHWCRTGTCHYGVKCYYAHVMPKTPEGLKAVDLERLPIWWVKRNRKATDKVTSDGVRSGPRRADTTAGTVHKATSPVPPLFAPGPTRTTTNNPRPARSNSSTSTADGGPYLNEFPHYKEKMEVQQAKEEGTYYAVVAKKLAAPPTQTRHTRAKSSVAAMAVHHPYSGLAMQMSRPSRISWTTATATRSRAQSVATSGATKDSDSSENSLGGGNIKNGGNGTAPPVQDINNLINLVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQB0</accession>
    <name>A0ABR3ZQB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Replication factor A protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ssb2</name>
        <name evidence="8" type="ORF">Sste5346_001042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A C-terminal" evidence="7">
        <location>
            <begin position="168"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="305" mass="31451" checksum="085A6C4D4D404122" modified="2025-10-08" version="1">MASYGGGYSKPGYSADGGNTGGGFMSGSQGGSQGGGGRNYNEDSLRPVTIKQLLETEEAYPGAPEFTIDGAAITQLTIVGQVGAVNPQPTNVTYRIDDGTGSIDVKKWVDADKSEDETEAPFALDQYVRVFGRLKLFNQKRFVAAHFLRAVDDYNEVSYHALEATYVHLTLTRGAPGGGDGGANGANGYHNKSEDGGMFVDQDNGGASYGVGGGASYGVGGGASYGVGGGGGGGGGIGGRNMTANAQKVFNLLRNMPTGSEGVDINVMKNELRISMDATMAAVQELVDSSVIYATTDDSTFALLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQG6</accession>
    <name>A0ABR3ZQG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="267" mass="28923" checksum="63213499CBD21C3E" modified="2025-10-08" version="1">MVLLHQVNPDEPKVSVENQDAQRHHAHQVCGIVAHTKDRGVASVAIRSLAISAHVLRDPREQDEVYMLLKKITAETGWRIGRIYAELQQVWGREIKDTAGNSSQSTTSATVSSSPSTLLPPPTDLPQPGNMFTHGFGQLGPGLASTSGSGFGSAPSQMQKVDFNTSASPMPTSSSGGRRSLPIWPTANTSTMFNVHNRHMHGMPTTNTNTSLASSSQSPPPTTAPMPFRPPHMSNPLMHADFSLPDHPYKAFYKPPNDSAHFNPQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR71</accession>
    <name>A0ABR3ZR71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TeaA receptor TeaR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="25609" checksum="3223B9CBB9A24A8F" modified="2025-10-08" version="1">MTRSASDLSPKKALLSGSSSTPGLRKASAPTKTMSSAGRPKTRNGASKDSNSTGTVATRPSTRSGDRELSREISAGAASKQPEGEPPWMISAYRPDPRLPPDQQLLPTVARRLQQEKWEREGKFGNVYDREFRPLTDEGFLSPPESPEKVAESAGTADQLSGKPDEWPLKPEAKGNPSHQGRAGSYSTIPKIQDKPTMSPLPSPRGPLPQQAESNTAQPASGNQEESGDAKQGCGCCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRB5</accession>
    <name>A0ABR3ZRB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Translocase of outer mitochondrial membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOM40</name>
        <name evidence="10" type="ORF">Sste5346_000516</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="356" mass="38739" checksum="882292FD0B3F28EA" modified="2025-10-08" version="1">MASATDALQSFLQTNPVAVSITDAWRSFTERRDKFGLSNPGTVESLAKEVQRDVLLNNHMFTGIKADLTKPFSVSPLFQVSHQFALGERLQPYTFAALYGTNQVFCQGNVDNEGQLSARFNYRWTNALVSKASLQLAPGDGQQMAQFEHEYIGRDFTTSLKMMNPSVLDGGLTGIYIASYLQSVTPKLALGLEGVWQRAALSQPPDAALSYCARYQSNDWVATAQMHPQGAINTSFWRRLSESVQAGVDMTLSLVPSQAGGMMGGGLQKEGLTTFGAKYDFRMSTFRAQLDSRGKLGVLLEKRVAPPVMMTFAADVDHATQQAKIGLGISIETGGEDIELNPDGSPVHAPPNNVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRG1</accession>
    <name>A0ABR3ZRG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YCK2</name>
        <name evidence="8" type="ORF">Sste5346_000561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="451" mass="50513" checksum="B283795EF50C4CB9" modified="2025-10-08" version="1">MASSSSNVVGVHYRVGKKIGEGSFGVIFEGTNLLNNQQVAIKFEPRKSDAPQLRDEYRTYKILVGCPGIPNVYYFGQEGLHNILVIDLLGPSLEDLFDHCNRRFSIKTVVMVAKQMLSRVQTIHEKNLIYRDIKPDNFLIGRPGTKAANVIHVVDFGMAKQYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGGLPWQGLKAATNKQKYEKIGEKKQTTVIKELCEGFPIQFEKYLTYVRNLGFEDTPDYDYLRDLFTQALKETGGVEDGEYDWLKIGKDSSKKTDWDRLHNPNQRPGPSNMELHANSRGGTGTPHASDPRARLTVDRLNAAQPPPPSPIKQNPRKDRQNAPVATMGGRGSGAGGLRDMATPTGSTQAQFQNSSQNLPRPMHSQHGGMQAQQQQQAAAARGAEPQPSGFSKFMKSFCCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRH4</accession>
    <name>A0ABR3ZRH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="308" mass="34490" checksum="CFE332FB570F4B6A" modified="2025-10-08" version="1">MPSTHKGQGPAPIIMELATDDTDASYRSALNLFLQAKQRPNQSPEAFYNYIRRLEKRLEYLPAHFLSGHLYAGLLPGLQEGLAIRGITSKSTREEIVKRANTLWEPTSLTATRVEALAAEAAEGSGSAETSAGTTTSTEEMRRAKKWAKRVAKRNAQRKRRQNIALRSIADEPREYMPGLAIGPVRRVVRTTGYVTYDPDQNQIQNQDRNVELSGLAIYDDGQEDIRTRSHGVKQEDRGDEFYYASPIYGPDSLLERIECPSCNTLGHFARDCPEARPARRSYSRPVRGRGRGRGRGRASVRRRGASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRM4</accession>
    <name>A0ABR3ZRM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PEX6</name>
        <name evidence="13" type="ORF">Sste5346_000626</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19527">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056995">
        <property type="entry name" value="PEX6_4th_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047533">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23315">
        <property type="entry name" value="PEX6_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23120">
        <property type="entry name" value="PEX6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="1152"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="289"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="590"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="704"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1047"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1428"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="342"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="709"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1428"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1460"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1477"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1498"/>
            <end position="1515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1903340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1554" mass="166513" checksum="608FB5A209C73E13" modified="2025-10-08" version="1">MAAMAPPPQDVASRPIRRRRRRRRRLDKPPVNARLVLDDHVRGDVGILSEDLFADLFPHLYQQEQQQKDGANGFGAALARATPTSTAAASSIAEPDVYHVAMAPWAPSASPESTDWTIVPVAKSSALAPSTVQFSPSSLALQNFAAILQQVAPSKFSGHSRRGIEILLLDVEAVSLDTVFVSLEGDLGKRLEAGEGTFFREHPAASALQATKNKAKGANGEQVSSEDRLTAALRVALGTLQVVHSGDLFPLPLPPHPITHVPPNPGKVTFCEPVAQGVLSPSTRIIVSRGRLHSKSGRNRGADLAPIPARRKLHGVSEDEGDDTANDQFFSAAEERTRTETETDAPTEDSEVTESEADMSPVDQDDDLEDDDGGEISDDSMDEMISLQAPTLPATLASGVSTLAPGSPMTIGRGRRTNGVATPGSVFSSFTATTARPDRPRGRLFKAQGLTAPIPPEILHPKPGADDDDEARVYVDVNNLTRIGCFSGDWVRLEEAEEPPVNGFGRFALGSFGEPVGDEPDWRPVRVFGLPEGYSQRPVTRIPSAKHEAGGRRLSFFESQIQRPSSPIAYLSPVLLANMQSTPYLRLSPLRGAQHPPSSSLSRHGAHGRSSTKMGAAAQPPFAQKVIIQQVRTPVPIEKSVQTAVVAGLKWHFEKKLRVVKTGDYIAIPIDAQLGRTMNDMLLSSENAAVTDILSLTGGIKEPSATANGSNGTIGSAATSGTPASSASASVGSKPILKADEVAWFKVTHVQPQPQPQQQRHYLGEDGEEEESVWGTTVACVDISTAHLEQSGTTTSRIPGTKDSNWPYYLGLREPPRRYGDRAAPAVVEPDRKQVSPLRRQLRDLVAAATSKRAIHLNMPPVAILLVSTQRHIGKATVAVNACSDMGLHTFTVDAYDIVNEASAGGGDAKTEGVLKGRAGLAMSCGPECCALLIRHMEALTADRMVSSIKEILEDARVLIATTTEADKIPDGVRSLFTHEMEMHAPDETERQSILRNIVNDRALVLDPEVDLGSVALKTAALVAGDLVDVVERALVCRQSRLEKLVVDQSTPPASSTDDVGPDPEQQLNSKVLTLRDVQVAGGAAVRGLTKADFDAAVDAARKNFADAIGAPKIPNVTWNDVGGLDNVKDVVMETIQLPLERPELFAKGMKKRSGILFYGPPGTGKTLLAKAIATEYSLNFFSVKGPELLNMYIGESEANVRRVFQRARDARPCVVFFDELDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSGGGDDEDEGSGAGSGGVFVIGATNRPDLLDQALLRPGRFDTMLYLGVSDTHDKQLTILEALTRKFTLHPSVSLRSIAQKLPFTYTGADFYALCSDAMLKAVTRQASAVDAKIAAMTKSGKKPISTAYYFDHYATPEDVAVLVTEEDFLEANRELVPSISAGELAHYERVRATFEGKKKEEKDKEQQQQQQQSASQTPAGFPLPALTAAQASSSSSSGSGPASHSAKHARKGKGKAKATSLRFSDVEEEEEEDNDKNDSDDDTGSVILNGRPTSKGSSKGKGKAAAGSFQDQRASDDEDLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSB8</accession>
    <name>A0ABR3ZSB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="251" mass="27390" checksum="8697FBA251442F99" modified="2025-10-08" version="1">MAHDAPPPNYYAILEVSETATSQQVRDAYKRAALKNHPDRVPQDSPERKTRTRKFQLVNDAYYTLSDAGRRREYDAQRRLFNRRGYSFPEDDDEDDEDSEDYPQTGTGAGSSARSGASWAWNFFSNATGGGGSNNDHGQANTEEARQQTEDAQFADVFEEMLREEGMAEPGGRPTGKFWGFLGGLSGGALGFIVANVPGLVAGAVAGNRLGAIRDTKGKSVYAVYQDLPADDRSRLLGQLAARVFSHAVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSJ0</accession>
    <name>A0ABR3ZSJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FAM32A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013865">
        <property type="entry name" value="FAM32A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13282">
        <property type="entry name" value="PROTEIN FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13282:SF6">
        <property type="entry name" value="PROTEIN FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08555">
        <property type="entry name" value="FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17811" checksum="E393B50E47C13E1A" modified="2025-10-08" version="1">MPSDEYASASGGALRLKGAKVEKHKSKKHKKKRSSRDKDREGSRARHAEDELEKVGSDGEDRGIKKKSKKKDSGSGEEDYDDYEDLKNDPYARMTPAERRFAEAQDKKIRDLMHASPEDARAARPELFKSHKERLADLNTYLSRLSEHNDMPKIGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSL5</accession>
    <name>A0ABR3ZSL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5'-3' exoribonuclease 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RAT1_3</name>
        <name evidence="1" type="ORF">Sste5346_000322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1903693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="109" mass="12224" checksum="43D3EBD028693E85" modified="2025-10-08" version="1">MTNWAPGEKETKVVDMSGSPYMALILARVGSVEELKDSLWHAGISPTSLPNLAHVHSIQDVSAMKEKDLLLNTAMELVDFQYLEDALQNRTLLWLNELAKEKPNVILHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTG4</accession>
    <name>A0ABR3ZTG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MCX1</name>
        <name evidence="5" type="ORF">Sste5346_000295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="4">
        <location>
            <begin position="491"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="624" mass="69499" checksum="667199DAF17625B4" modified="2025-10-08" version="1">MSVVAKPRSAALLGVPFPASGTVVSHSQPPFILAHRRRLSISRPALTANRRTQEFNSGFSSSYDPTEDNGRGPMFNKAKFGVPQFYPRDLKKRVDDYVIGQDRAKKTICSTIFNHYQRLRRKHHQEDSDRVLREKLQRQRFARDRDLHEKHNESGMDGMSTLNPSYKAQLANPETTDEFPDRVEEAAYAEQNPDPSENFYAKEDPTIPQHTKIDKSNLLLIGPTGVGKTYILEYVGLEPSYCVGMLHSLTFLRRTLSKKLNVPFTISDCNSFTQAGYIGQDVEACIERLLVEANYDTKAAEYGIVVLDEFDKIARRETSHGRDVGGEGVQQALLKLVEGTRVTVSVKDNRSSSRSASPITTTYGSPNSTSPPQATPPSGKMDQYTIDTSNILFVFTGAFVGLDNHVIRRVARPSIGFGSEIRSTKGSSLSGSKAVLPLESYKHLPHQPTFVDPTTVGFTPLDLASPLDLQAFGFIPELIGRVHNICALSPLSLDELYRILTEPRNSLVEQYTSLFDTYPSRLRFTKRALYAIAERAQKNETGARGLKMEMERVLAEPMFDAPMAYVLITEACVKGKEKPGYWGKDGRFEIERRIRDEDEGLNANGEAVAGASFEQLREAGQSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTJ6</accession>
    <name>A0ABR3ZTJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FTR1_1</name>
        <name evidence="8" type="ORF">Sste5346_000033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="407" mass="44635" checksum="E1B2113DE3FF75A4" modified="2025-10-08" version="1">MAVEVFSIPVFLVVFRESLETVIIVSVLLAFLKQTFGRDETTTGNVEIARPADNVNGSTDIASTNRRNTPYRHLVRQVWIGTLTGLVICLCIAAVIIAIFYTVGTDHWAASEENYEGAFALVASLIISIVGAALLRISRMQDKWRVKLAAALQRTGQTTAEARNEEGNATKWQRFRVRVETFPERYALFVLPFITVLREGIEAIVFVAGVSFSAPAKSVPLPVVVGLLAGISVGYLLYKGGASARLQVFLVASTGLLYLVAAGLFSRAVWSFEMQVWNKVVGSDAAELGSGPGSYDIDKSVWHINCCNPELNGGGGWGFFNAVLGWTNSATYGSVLAYNLYWLVMMLAFASLRYHEVHGAWPWQWTRRRKPFDSAGLQQQDLQLPDIVPVSPLHPTTVTEVASEKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUD3</accession>
    <name>A0ABR3ZUD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="59714" checksum="2680AB02791E77D1" modified="2025-10-08" version="1">MALFTLSAAGLASTSLLLLVLYFAYTVVYNLFFHPLRNFPGPILHRATRLTYLYRTMRGKMPFAILPMHDRYGPVVRIAPDQLAFLDLAAWKDIYGRRNDLLKGAPVGDGDHDELLKSAHGAAGVDELSKDPRFYHIDGVDESILSESRANHARLRRQLLPGFSDRAMREQAPMIEKYVTLLVQRLREIATAPAQKSADMLCWYSWTTFDIIGDLAFGEAFGYLASGDNDGKQPWIDALTAVYTGPAVVFCKLVSITGYVFPVLARLFPAMAAHNQGGIDKIRRRMALPERRPDLIQGLVDKNDQDWDSSLTIQQIAGTAGIVVLAGAETTTKLITATTYFLLKNPEALARATAEVRGAFKSADDITLMSATPTTIPYVLACLNESLRRYPPAGVGLPRVTPPGGAMIAGVFVPENTAVAVWQLAMNHAEQYWEAPYEFRPERFLDEGKTKYAKDRTEAMQPFSVGPRNCIGRNMAYAEARLVIAQVLYNFDLTLAEPEKADSLNWLNQNAYVIWDTPPMRVFLKEASKKPSEAEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGR2</accession>
    <name>A0ABR3YGR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF6">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="75545" checksum="DE2844BCBA6C2512" modified="2025-10-08" version="1">MEIACRVRKKRCFHTAADTKPERVAAADNSNNVSNNNHNANNKADRIVEKTDRCISVVSKELPPAIAIKPPSSGTGSSETRESSPKPGRSIDYIPEIALADLSDGQDSDGPDDDEDDEDGARVENTETPPSSTKRTPPGVGPPPSKRRRQSDAKRAQRQLAWFYHKYRPRNAPVVLTEPHRRYLEDVGALLELPKATADACLSIYVSLLDDLIPVVDGASVFRGYSNGQTSIYLVRAMCLVACKTTQATPFLRLSDDGPILTPLDFAARLLTGLDAAIKADLEPDRITKVQILALMHLHNDGTTGTRRAASCLAQAVCEAWSLSIHWRLPTTPDQGTTSSDYLWWSLRNLDRLSKPIMAAAPFLINDSDIGLPRITATGKDNSYRTQVMALATALGDLLATATSIFKATSKATVDDCQEFPTFAAVTSGAGVDLDNFHQSHRDYLEIWYCVAAMLSCRYSGPGTGPYQRRLDAAIRVLSLITDGQHTRLPPLPLVPYALSMGTTIIYRALRDKQRDNPTSRRDLARCCEALDGLARLWTSVAAVAKLARRLLRLLGLRAGEQQKEAKQHADEINGLHSAPLPPATDWQYSTLPLTTGVAPTLDFEAQLAAADGWSAGSSGFDGMDGFEGFANFESPGTYPQFDAAFHNLFDFAMPTAFREQDAWAFFPTAAVAGAGTSADGGSSTGGDFHMAAHHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH23</accession>
    <name>A0ABR3YH23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_010322</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000132">
        <property type="protein sequence ID" value="KAL1887265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF38">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="11"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="55488" checksum="3111AB0EE259A52A" modified="2025-10-08" version="1">MVATSAYNLSIVMFVALSSLTYGYAFSVFSTSIGQVGFYEYFDLSTTGPRAGYTNSMLGAINALFSAGAAFGALSIAWLPDWMGRKKTIQLAAVVSLVGGALVAGCATIPMLVVVRLIQGIGVGQCITITPVYLSEVAPPARRGFLAGQNAVGLVTGYFIASWVGYGTYFAKDATFAWRFPLALSCLFPLILIVGSPWIPESPRWLLWKDRADEAWVITERLHRDPRDPGQTQAKEEFYQMRSQIEFDRTQDLSMWYMFKKPSLRHRILLSCGILFGGQACGPLVVNNYSVLIYENLGMSGSMPLLMYAVYVVVGASVNVIAAFIMDRVGRRPLLCIGFLSTTIAMSVETALVAKFASTENKGGNAAAVLFLFLFVTGYGVCIDSTAFVYCAEVYPTMYRAKGMALGLFVYYVGSIAFLTPAATAMANIGWKFYLVFVACSFVAFVLTYFFAVETARLSLEEINSLFGDTVVVNWTNATAEEKAHIDEVIAEKARGEHVDVIENNDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH35</accession>
    <name>A0ABR3YH35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000127">
        <property type="protein sequence ID" value="KAL1887330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18497">
        <property type="entry name" value="BACK_ABTB1_BPOZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044515">
        <property type="entry name" value="ABTB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="148"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="380"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="674" mass="75119" checksum="C30AFE00620ACEA9" modified="2025-10-08" version="1">MAMPKGQLEAKLKEEHELIDSGVLREENPLDLTEDFGFFLEACRRGDLKECQNYILGGVNINGKDEYDYTPLIVASLCGHYEVAQLLLESGALAERNTFQGERCLYNALNDRIRNLLLQYDYSKSADPLQPWSSHITSLLSRTEPKTSDITLTASADGPRLTSEEFQLHKFFLAARTPYFHRKLTEAPDMASWKLSSNIAAAAFRIVLHYLYLDDITPHTASLSDDEEALFRSIDKITKQLEVEQLWEAMLVGNDRRLARQRYQDEVERAQQQVDAFFRQHVLGNKMVVETSKVNEVKWPHDNFIFADCLLCAEETTDEEAAADETGNDTIAAPERTNSIPIGPAANGASTPPVLRENGTSDTKTNGARAPRKPRRSVLYPAHKALLVRADYFATMFSSAFLEAQASVHLRIIKVDCAPEVLEIVLSFLYTEQADIPLELALDVLYMADMLFLEKLKTKAAVIISTLGSGNRNVLIDPTHQEGTDAQEENEINVYDVLRAAWDLKVQRLEDFAARFLAARLEHYIDEEAFADLVKESASRLKTRHETDTIELIDDIRYFLSERFRLRFEDVALSDIEDEDEVEAEAKAAAAAAAAAVVAVDAAEGGVKEAAENGDDQNAVPVVAAAETTQPPAAGIIRTLDGNIVEDEFDSDALNYQILLGKIDSLLQRLGLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT9</accession>
    <name>A0ABR3YIT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetolactate synthase, regulatory subunit</fullName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ILV6</name>
        <name evidence="8" type="ORF">Sste5346_010283</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000126">
        <property type="protein sequence ID" value="KAL1887344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="entry name" value="ACT-like. Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054480">
        <property type="entry name" value="AHAS_small-like_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053050">
        <property type="entry name" value="ALS_regulatory_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31242">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31242:SF2">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22629">
        <property type="entry name" value="ACT_AHAS_ss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="96"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="301"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="330" mass="35751" checksum="113EE0B3CEC55033" modified="2025-10-08" version="1">MASRRLLLSSPWRAVSSSGLRLAQGFQLSTPTLAVSLRYSSNTSSSTSAIAYKALRRRQAPLPVSDAPPSWSAQAAVSNILYETPTPSLAPSTRHILNCLVQNEPGVLSRVSGILAARGFNIDSLVVCSTEVEDLSRMTIVLTGQDGVVEQARRQLEDLVPVWAVLDYTNAALVQRELLLAKVNILGPEYFEELLAHHREITAPVDANGEQDGEAFDVSLAEVSEDFHPSRLAASEALRHKHEHLKSITYFTHQFGGKVLDISTNSCIVEVSAKPSRIDSFLKLVAPFGILESARTGLMALPRSPLHGPDEDTPTKEADEVVDASQLPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ20</accession>
    <name>A0ABR3YJ20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribokinase</fullName>
            <shortName evidence="9">RK</shortName>
            <ecNumber evidence="9">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RBK1_2</name>
        <name evidence="11" type="ORF">Sste5346_009721</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000098">
        <property type="protein sequence ID" value="KAL1888183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584:SF166">
        <property type="entry name" value="RIBOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="10">
        <location>
            <begin position="13"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="271"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="309"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="363" mass="36997" checksum="13F3D28076B9F6D7" modified="2025-10-08" version="1">MASSTSAGDGLPRITVLGSLNMDLVSYVSHHPEPGETMTSNGFAVSPGGKGANQAIACAKLSRKKAPAAVEGQPLSTTDATAHVSMVGAVGDDAHGTALKSNLEAHGVDVSGVQVVTEKGVPSGVAVIVVDEPTGQNRIIFSPGANYKIDDKAGTASLVPADTQLLILQLEIPLEQVLRALREARAAGIPVLLNPAPAPATEEARSQLEAAFAVTVGHEGKGQGLAHLVLNETETAALVPGLAVSDLDTEEGLAKAAKYLLALGVENVVMTLGGRGVYYASAASPSANGVGELLPPEKVAQVVDTTGAGDTFAGQYALEAVYATAAGQRFDCAAAVRKSNRAAAKTVQRKGAQDAIPWQDEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ95</accession>
    <name>A0ABR3YJ95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="163" mass="17733" checksum="3505D2E0A9EEFC5D" modified="2025-10-08" version="1">MASSYFLSGLTTRESILDAMTRVLVALDQNDVGLFNSAWAGEDILAQIGVDENKKVLPNLSVVRKVVFDRIGPMDTTHSFTTPRVHVEEGADTAVLTAVSLAQHCPVGRGKEPDGPKYLVGGEYTVDMVKDAADGQWKIKKWILKINWAQGDNSILDGPPPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJP2</accession>
    <name>A0ABR3YJP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42095">
        <property type="entry name" value="YALI0C12166P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42095:SF1">
        <property type="entry name" value="YALI0C12166P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="284" mass="28803" checksum="A0E2D0CCF6E5F348" modified="2025-10-08" version="1">MPSSQRPFFLSSFFAAFRQQPTSTSSLSQAAAAQQANKHTSAGNGGSSPGSNNQSDIVAAVAAASSTSGSLGSPPSSSSSITSIAGGTASASTSTSFATAAGSTTAAASNTSTSTSNANNSRSIASSAAAAAAAALTASQRLHTSRSPHHHHHHHHHHHNTHNSATASAVPIPNSSAGGHQQQQHSNSGSNHGSFTEEPYYVSGYSAGTGTGTPTPAPTSTTVVTATGRRRGSDSSSEGFREVLGADKWYIGGRTAAGEERFFKLGVVRRVRSNDRLSLDRLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKG6</accession>
    <name>A0ABR3YKG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Solute carrier family 25 (Mitochondrial citrate transporter), member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_009579</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF4">
        <property type="entry name" value="TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="23"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="113"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="210"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33034" checksum="C26149267D00EF11" modified="2025-10-08" version="1">MSAAAPVAAANADAGAPKKKKTPSPLRSIIAGSTAGAVEIAITYPAEFAKTRTQLNRRLADGQKLPWPKFGPQWYAGCTTLIIGNSAKAGIRFVAFDQYKQLLADADGKMTGPRTVLAGFGAGVTESLLAVTPTESIKTTLIDDRKQAKPRLRGFLHAVPIIARERGLRGFFQGFVPTTARQAANSAVRFSSYTFFKQLAESYTAPGEKLGTVGTFSMGALAGLVTVIVTQPLDTIKTRMQSIEARSVYGNSLRCASLIFKQEGLLTFWSGALPRLARLVMSGGIVFTMYEKSIDLMDRLDPESNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKN4</accession>
    <name>A0ABR3YKN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07406">
        <property type="entry name" value="MPP_CG11883_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041821">
        <property type="entry name" value="CG11883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="28"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="6">
        <location>
            <begin position="330"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="534"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="74882" checksum="5409B9B0B864CDA2" modified="2025-10-08" version="1">MCAASISADGTEFATYTPDHSIDLTPDLRILHFNDVYHLDPSSAEPVGGAARFQTAVDEYKSAERFNGQPELITLFSGDAFNPSLESSVTKGSHMVPILNQLGTACACVGNHDLDFGVKQFEYLTGKCTFPWLVANIFDPALGDDVPIAYLQKTHMITSSNGIKIGLVGLGEREWLDTVNALPPNIVYKSATETAKQLIPELRKAGADMVIVLSHAREPNDIKLAENLNGEADLILGGHDHYYSHRLVNGTHVLRSGSDFKQLSYLEAWRRPGSAGDETKGRWQFAIRRRDIVSAIAEDKPTLSLVDELTAKLKQSLEKAVGWTAAPLDARFTTVRVKESNLGNFVCDIMRLHYQADCVIMASGTIRGDQIYPPGPVRVKDITDCFPFEDPVVVLRVTGQAILDALENGVSLYPALEGRFPQVSNIKYEFDPSKPPGSRITKWELGGVTADLKKEYVLCTRGYMARGKDGFTSLLAKSEGGTVEEIVNEESGILISMMLRQYFMALKVLDQWIYWSPSMENHWNRVVSDIDHHHPHLRPNSTTTSPTASPKVTHQGDAQDDSRPRKRPRASDDGEEGWGNWTAARLRQRRCSAVPFNERVVDNATPAKNTEEMRRIDRQMHIMRRVARKWRRLAGVPSRLGDTLTEEEYEADWTKAIAPRVEGRIIVVGEGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLD6</accession>
    <name>A0ABR3YLD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase assembly protein cox19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COX19</name>
        <name evidence="7" type="ORF">Sste5346_009435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the assembly of mitochondrial cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the COX19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051383">
        <property type="entry name" value="COX19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="108" mass="11780" checksum="646E83FA3EF67E5E" modified="2025-10-08" version="1">MSTFGSPGGGSIATKPTPPQRGSFPLDHEGECKQVMLDYLSCMKKVKGVNEDECRSLAKSYLGCRMDRNLMAKDDFKNLGFQEKGDKAGSGKDGKTEGETKSPGELRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMJ7</accession>
    <name>A0ABR3YMJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secondary metabolism biosynthetic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="423" mass="47104" checksum="6F8C59FBA4CC8E75" modified="2025-10-08" version="1">MAKQDPATRRVSNMTSSQVEHKRAIDRANQQICQRRKRAKMQWLEGEVIRLTGQLDAAHERIRELEAGAAAVAATGGVPVYQPVPIDVTMDVPLNPPVIIEPAVLEPVLEMPSLNTSTSPSTLASTTSNTTVTTTSTAATSEDPRNDYDSIWTVHLRELLDPAHNDDYGELGNIVFEYPMPPPDTPSPQYGEGGEITLPDWQVVPLHLPPETDLDRFIIETTNSGRRLHQQTGAAELSQAQFPSISSLLNPNLGDDGTRPLTFALATHVVRNSTVKSITTRIALMYLLSHLLRWLVCRNRQTYEKLPDFLKPTHLQRTVPHPAWVDAITWPAARDNIIRTEAWKKITFDEFRRVTGACMSVNWPYTDSGAFSDLGDGQNLVLSPLFEDHIRRASNWTLSKSTAARFPFMKEFCVAVHEGEGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN77</accession>
    <name>A0ABR3YN77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Palmitoyltransferase zdhhc13</fullName>
            <ecNumber evidence="5">2.3.1.225</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ZDHHC13</name>
        <name evidence="5" type="ORF">Sste5346_008853</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="424"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="563"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="590" mass="64858" checksum="74B2A708D85A863D" modified="2025-10-08" version="1">MSLGNDWYSRETLPSLPDDFPILSQRCHIWKTEAIYFAIAEDNLPEVHELIRLLGPEVLYVCDMGWSSENLTPTALHMAAKRGRMDILTALLDYRDSLLPDERKRWEDEYERDEKKWADEDPYARPWGTPLTEACMSAQADAVQMLLARMPEVDVNASDKFGFTPLQAVAKHAVGVRPHTDPDEPARRMAIVKMLLAKGAVPRSTDGKLGRPNPLLLTLMADRGQGDAALTRFFIDELGINVHASFSWSTARLDGRGVNGVTDDDKAIDRFDSKSNDNDVYLSPLATAALFGNAAGVETLLRTPITDFVKDLVPATGLPPLHAAVVGVPHLEAPILEPGGPEPTYHRPVRFVHNNKVFLQQYGQWHDTLSNEEREAFWAAYDVAGVADRAAYIDARVATVQLLVSAVEAVSGYLTPFDINATHSRYTPLHLSARFDRLPLLRVLLDHGADPNIPIPGEKGKSVLATVTASVHRLCARNSRVAYGQPWQSGGGAWAYTPYSVVVQSIDARIGEGMTTLLRELSTASDDVNEVDADGNTALYWTSGYGLPNTTKALLVMGARPDAQNHAGEVPTDGTVPTTTRPANNFRDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN85</accession>
    <name>A0ABR3YN85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008679</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051837">
        <property type="entry name" value="SortingNexin/PXDomain-PKLike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22999">
        <property type="entry name" value="PX SERINE/THREONINE KINASE PXK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22999:SF23">
        <property type="entry name" value="SORTING NEXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PXA" evidence="4">
        <location>
            <begin position="79"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="492" mass="53518" checksum="DC6AE400A8267FCE" modified="2025-10-08" version="1">MTEKPPISQAHVPSPPATRRAPPPLPRVPGIDPLSDKATILLIRRTLCPKDGATQGQGGSNTNGDATPIEDLLPPLTSRNDVDLQLYALLAIIVREFVLTWYSKITPDDDQFVTEIVQIVAHCTRALEQRLRKVDLESLLFDELPALLDNHVKAYRASRRPLVQPPVESDPRAVYHALWPLPALSPVPPVDAHLPGSGLGSGSRPTTASGPDIKLGEADLHKSRGDDINKIIDNDIALEQATNEAAYRQLLVRGLLAVLLPTEDLENECLTSLVSNIFAELLVGNVLAGRVAQPWMMYEIVGLVAKIVREKMDGDDNDKGPKQLAKKRRAAPKLLQKQTQSGQSGNWITTTAAPVFWSVLKIGFALFASIRFLVTSITLSRSLPLRGIVVTKVKEPIAEKEKETSTKDSNFLDVKLKPSSASIYSVATVATSVAGTDEPVVPVLAFSVWATISNVVQLDVRMPWLYGGLSMLQWLAMAGPGCIAALNRPLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP13</accession>
    <name>A0ABR3YP13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MFS transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
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        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
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    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
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        <location>
            <begin position="241"/>
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        <location>
            <begin position="365"/>
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            <begin position="410"/>
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        <location>
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        <location>
            <begin position="510"/>
            <end position="529"/>
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        <location>
            <begin position="549"/>
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            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1890041.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="64083" checksum="3176E985C7247CC4" modified="2025-10-08" version="1">MDEHLDDNEIREIEQILGTKIYPGTEIMRDVGSHHFVKAGQPQSHAADDNADGITQASSADPVLVPQPNDDPADPLNWTPMWKAGTIVAATVLSFCQNLGPLACAPMFGSYIAEWDRSLADVVQFTGVAILVLGFSNFIWVPLMVSYGRRPVAIFSTLLCLASSIWRAKATSYNSFMGASVLNGVGAGPCETLMPQVIADIIFLHDRGKYQTLYFAMYFISLMVGPIISGAMDFHTGWRSFWWFNTGILAFALLFQIFLFPETRYDRVAVQAATTAASSAASTSANGNNANSSNEGLGNSEKVAAAQEIAHATTATTAPTTKEGDGAVDHVDHFLGVSKPTVGNFALYQKNGNIRHLLREIWLPWYLHIFPIVEWAAFAVSWSASCFLVVNLSQSQAFAAPPYNYSSQTIGLFNLAVFIGALIGLFTCGPFSDMVAAWLTRRNNGVREPEMRLVAMVPYVLAMLIGSIVVAVGYDHHWPWQVIVIIGYTLLGMQVAALPSIVSTYAIDSYRPVTGSMFVAITVNKNVWGYGVSKFLTPWAEKSGFTAPILTNMGLTLFFCLLGVPFWFWGKKLRGMTRNSFVHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPC2</accession>
    <name>A0ABR3YPC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
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        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
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    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
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        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BLR8189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
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    </dbReference>
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        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="16"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="171" mass="18981" checksum="28E9613F3BB0B439" modified="2025-10-08" version="1">MCGPYTGQAEHHGSYPMNHVGVSVPDLDKAADWYINVLGFHELRARSETDRATNPEGGIFQIYPESLQKVRMAYLSAGNGVGFELFEFGSPKMETEQQANFEQTYFRGGYFHIAVTTPDLESTLEKVVANGGRQIGKTVPIYGHKAAYIADPWGNVVELITASFERTMANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ26</accession>
    <name>A0ABR3YQ26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008557</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="583"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="729"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="838"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="917"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="982"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1263"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="112"/>
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        </location>
    </feature>
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        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
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        <location>
            <begin position="173"/>
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        </location>
    </feature>
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        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
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        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="275"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="736"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="763"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="843"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="866"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="982"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1018"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1112"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1159"/>
            <end position="1170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1291" mass="139994" checksum="4A8AD6036BFB0C43" modified="2025-10-08" version="1">MDDVVVGGGPCPGGGPAPGSGAGSNTSRKRNRIRFSCNHCRDKKLKCNRVLPCDQCLKRSLAAVCRYVPYTAYPAGEAGPSSSASHARQPSLKRQHSMMDPSSFDLDQHAYETSSVESTSRSGSVVREHPQQQQQQQQPPTPLYHQQSFPDNSFQHYHHQQHHHHQQIPRSHPQQLQQSQQQQQQCQPQQIQYFQPPLQSRQQQRQPQIQLPLPPPLLQDTSSQSVPERLKYLEQLVMCLTARSRNQQSPGSQQTGEDDDMDAEGSEYDGDGALSSTESVRSVTRTRSILGPGGEINVAEFRYADPSNWEGVLDDIVGLTRDLVLVDDAVLLPGGWDFGQAGASVSSGAGANTLALFVGYNGLAPGSTDMLRFLPPRPVVDLLVDRFFKSLKDYDPHALHLLFHLPSFRRQYRIFWSDPQGAFLSYLALLFLVVAHAAMACIRDGDERQSPARGALGDDPLTIVDACRHRAAQCLTLDDYARPGRYKIEALILYFGVEYYWRRRLQAGVGSSTPSYSSPLASTAMILSLAVRLAMHMGYHRDPSHFGGRLSPFEGEMRRRVWLVLVNLDQTVCYELSLPSNVHHGSSARPGSGNSDTGLPRNLYESDLSEDLPTLPPARPSSERTGVLYAIARSRLLAVVADIMQLRPMSTTHTNTTTTAAANDTGNNLPDAAHGGTAPLPTPPTSGNTPTTSSTNSTAYEARVMQLDRRLMAAYRSLPSCLRLRDSKGGAAFGSETDSSGGSRSGESIMSGDTGRQRAAAATDRDPLDQRDPPDLCVERYLIEIMYQKARLVLHRQFQGTERASPRYAYARWVCTDAAVRLLWHQYDIYVAVQPAQGTSASKESDATDRSTRHGSIASAVSKTSSKKDKEKDAAKGKQGGRLAAYHWLLSDSAVTHDFLLAGTVLCLKVSYVTRRPTGVDGEPGVPAGGSSAEPDNGAVVSLPQLLGLIRTSRSIWASLQGTSSEAARAYSVLTRVLADAEAMEEEQSEEEEDEEEDDDDEVENSGDPSQFEPASPAFTTSTDRTTHTAGTGYSNVSARTVSTTATTVSMQSSHSSMSLTTTAHTLQEPAQAPIAQPATTTATETAEGESNDTSGSTTPRYGEFKEDPVASQQSQQQQQQQQQQQQQTVSTPVAPLPPPVVQIPHALHTPQGGMGLSQLASPTASEQWPGQTAPLLPVLLDTGMPTPVVGYGLPMQPTLSGLTGLPSGLNQASLLPTMYLQFPTSNSSSGLPTPLDGDNGMQGLADAAFPGDWNTLWPDQMGGGTRSDHNNRSSPNWNDFFVRGGGMDNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQI8</accession>
    <name>A0ABR3YQI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mso1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028095">
        <property type="entry name" value="Mso1_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14475">
        <property type="entry name" value="Mso1_Sec1_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mso1 N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="310" mass="30226" checksum="435E599A59EF2E32" modified="2025-10-08" version="1">MAAWYSNILTTTTSRISNLRANLLGGDADGDTEDDTHVCRVLRAYYTEKGRSFPQWLPPDPKAPPPPVATVVPSGPGVGSRYGGASLSGQGGVQPSSLSSLWDKGNAGQQQQQQPAGGSLRQTARVGGVQGNRLSPFSNRNSDPSGGGPGGPGGTAGGGSLAPRPLPSQRMGSYQSTQSAAGALDRNSGGGAPAGSAQDKLRNLFSSGGGSGSSSAGGSRSQSPAQYGSSQGGGGASYGRGGGGGQGGGYGGGGGGGGERPFVASNAPWATSSDEYQYSGGGGGGGRQGGGLPSGPRRAGGGLPSGPRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR33</accession>
    <name>A0ABR3YR33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="571"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="805" mass="90542" checksum="CA6581B12FDA1401" modified="2025-10-08" version="1">MAAQWLPKLRKLLPLDDGELTQIINYTAKLPKDKDDEATAHLEGLLGDSDEAKAFIAEFVKHRKEAASQTTAQTNGASTADENGGSPTYAPPAGPPPGPNGTGPNGANSGAPPSGPNPDNAPPPSYYAPPGSSMPIASNNNNVFGFTSRHSNALIQASNIRARDEQEMQNALQNLQFEYRIYNPEIEPEHESDYYCNCSIHQFMRRKMNRLGVQRMWSDAVMYPGERFYSNVSLTPTLFSSNPYYLRCGSPFGYGLSRSFNSSYLWGPPRPSAYAHMAWTQSTISLSNQLNREAQAKVDSKEPATSIWEIVPNMGQLTIEEKGPKSEKASKSEKGDFKGDKKGDSKDSKDEKDEKKLSKGGSSAGKEKIGRFASFKKSLGIKSSEEKAAEFSSSLRTSILSEEAGRWPDNAHRQLVASYQEKVGMAKHIADLRARKPIQYLHLLRAGYFEPIPVAWATQLSNPLKFSVEAREGWRGITPAWRGYEDLAEERLYWVLNHREGSVGMRMKPDFISEMDMAQRRMAAAVEPPPMYFSPDDTCMRLHTTNDAGYSKQVMPTPFRAYDRPETPNDDSMILLDVSGSMDFDPVRPMYDRYLITGYARSTQPKNKDVAKSIIRRFVDALAHHDHQTLGYDLVTFANRATYIGAIHHRNFDDMWRGVRVGGGTRVMTGWQKVKELHFQKHRESAIHHPIYGWQAGPETPILRLLLFLDGEATDMDEFELDLLGLSWAHVTIFLIGVDNCPHHHRHANELQRISDVNHHVSFVDAQGNCPERFVTHELLKRHLGYDISLQEFEEMEHLPAYTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR78</accession>
    <name>A0ABR3YR78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GATA type transcriptional activator of nitrogen-regulated proteins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SFU1</name>
        <name evidence="11" type="ORF">Sste5346_008357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="105"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="293"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="237"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="346"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="417"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="642" mass="67210" checksum="D4B63E580338E8D7" modified="2025-10-08" version="1">MRSALPSRPMTNSSSSKTDPDGNSSRTRIRSPPPEEGGATTSNRSSVARSPNNRQRNSRSPMALSQPLSPASVAAETATAQQSAMAGSQPDTDAQSDAGSSVVQGLSGQVCSNCGITRTPLWRRSPQGAIICNACGLYQKARNTARPSYLKRPPTTSAAAGAGGARSRKNADAISTSPQSVSQLHSATPGATYVAADQSSSGTCPGGGHCNGTGGAEGCSGCPAYNNRMSKSANISVVQGDGSGSVPPEHTGCGSAKAAASGDATGRAGSVDPAAPIDMTNLQSQVSTVIIACQNCSTTITPLWRRDENGRTICNACGLYYKLHGVHRPTFMKKSVIKRRKRVIPTAQEGQGDEYSSSGEQGVSPPPGAPASLASRSDSHPGEDVDMERGTVNSDGSVNLGLRRRADHALSLVPEPVLRQNQQQQQQPSPRLPGGSDLNQYHSSSSSHQQQQQQQPQHAHHHSTSQRMDISGSLNDDNRLPPLTSLASMGPIERQPSLSPASFLSPSRKRSFSSSENDFGGQSSHNDGKAAYGSISGGSVSGNNNNGNNNEASSKRMSSIKSILNAPAYDNDDNSLGSMAGPYPGIGGGMTSQPSHPSSGGIEMRRNNSQDQRLEKRAALQREAERMRQMLADKERELAELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRA3</accession>
    <name>A0ABR3YRA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="299" mass="32290" checksum="624676275D27FB54" modified="2025-10-08" version="1">MASTVKTYHLAPTFDFAPDGPLALGSVLSTVKRPVPPLTIGNVGSTMTTTDDASTTPKIFSTTKTNYTLTTSTKRTTSAALSLDFLSSIFGVGPGGSNSHNRDSAVLFSFARLDTQEWYPSTEELESLIRQPTVSQYLKVLRSWVPKQVFVVTGIKIAYGAYAQSKKARHVDTGFEVKLDPGTAAGVSDIVTLGPKFTHSVKKGKYVEWSTGVDGEEDIGFVFAYKVQRVTVKLAKKEGKYGVTDHDEYTSGSMLGVDDHVASEAEQFEIDTVDTDEVDEGAVLLEAGDGTEILWLVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRK2</accession>
    <name>A0ABR3YRK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AMT1_1</name>
        <name evidence="11" type="ORF">Sste5346_007938</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="37"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="478" mass="51162" checksum="516F7DEC5E353589" modified="2025-10-08" version="1">MSAGPLEVYNGTAGVADNGGDSLTSDLNVYYSSGDFAWIMTSAALVLLMIPGVGFFYSGLARRKSALSLIWLSMMSIAVVSFQWFFWGYSLTFSHTGSSFIGDLSNFGLMKTLGQPSVGSSKIPDLLFCLYQGMFAAITPALAIGAAADRGRMLPCIVFMFIWATIVYDPIAYWTWNANGWTFKLGGLDFAGGTPVHISSGAAALAYSLMLGKRTGYDKNAGLPYRPHNVTHVVLGTVFLWVGWFGFNGGSALGANMRAVMACVVTNLAASTAGITWCLLDYRLEKKWSTVGFCSGAIAGLVAITPASGFVPAWSAVIFGVVGAIVCNFATKLKFYLGIDDGLDIFAEHAVGGMAGNILTAFFAADYIAHLDGFTEIPGGWLNHNWIQLGYQLADCVSGFSYSFVMTCIILFLMNLVPGLSLRVTAEEEEMGLDDAQLGEFAYDYVELARTPSEHINGEFVPSTPASVHEGKETAPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS62</accession>
    <name>A0ABR3YS62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="478" mass="51095" checksum="D2E95B059AEBA140" modified="2025-10-08" version="1">MTFHRNQAQFVRARWRRAILFPVWAFQTALLLAILGVFSYRLAETAEHFAENKKAGKVPTVELAWEVTNVALGVLCLVLTIMEAARLLAETLTPYFLLACHIIKMTCAAAMLALDIVVYINRSEGNWSSIGLALDVALLAAMLGLFVYAIVTYRRLVQSYDDYYHDPSRNTKAFGFGNGYDEIELGGPGARTSTSGLVGNSAAMGSASGGVASGDVYLRAGPYNDGPTEYDPAANTGGEASGRSRSVSAASSLRGSPSGAVGGPPGALDQGSRRASYNHERDTQFDSYVMNRASAALSQDDVDRAIHSELWGTARPPSGTISVNTNVVGSTVERSNSVVATGTVASHHAIPATTPQREAINRTVSWSVEHGLVSVPESLNEDYDGTNTLRTVGSVATIAEEYEGQAHGTQGVRNAAAAAYGERAQDENEVDIDALAHGRYRTKGANEDRALLMGHSRQGSLEDEEDDERGAIPETVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS98</accession>
    <name>A0ABR3YS98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ADI1_1</name>
        <name evidence="9" type="ORF">Sste5346_008378</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat striatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013258">
        <property type="entry name" value="Striatin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08232">
        <property type="entry name" value="Striatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Striatin N-terminal" evidence="8">
        <location>
            <begin position="45"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="592"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="807"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="195"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="617"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="751"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="243"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="762"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="886" mass="94336" checksum="CE3BBA74B388F480" modified="2025-10-08" version="1">MSWNGQGNMGPSPGGGGGLGGLVANDMSGGMPGSAGNQPHATEYTLQGVMRFLQTEWHRHERDRNAWEIEKQEMKGRIASLEGSARRADATQKALKKYVSILEKKVKDQSTQLKSKASTNATTDSPEADKQKQASKILEKLRGIQDDKDAQLPPAGANPEYGGRSVAVGDEEEQRSDLRVFLDQCQAEFTYLMVTPANPMPPRESPPLPLMDDLREDDFGLPAGQQQQQQQQQLDQFVPPPTRAAQQNQNQNFRQAQSSANHVSQQQQQQQQQQQQQQQGQQGNYPSRNAELQPTPMTRSGAEVNPSAYAAATAASDWPPQTSQAAQSSHPLEERPSQQTDARATAVGEKSNDAGPLTEPDAWDFNDGPSSFPESAPQQQQQPVSNRPDTDIFPAADSIPKSPNRLPGSHRRKGSMSRRRSAEHELSLISASQKTQKTENGNFKMRFGLRGHLDTVRTVIFSGGGSPGEPEICTAGDDGLIKRFHIPRTTYLASGNVSDLDVQADFTHRGHHGAVLCLASWFAAPNFSTGGRAQGDGWIFSGGQDNFIRVWERGRVDPKATIDGHTDAVWALCVLPATLGAVFGPSGSTYGSPDRIILVSGAADGTVRVWAVSAPPQMTSPQPAGAGAANANLGQQRGGRAGTGGRVRGNSMSSGSGFPSSPQPTVASNSPFNYTLVHTITRAGSKASPTSITALSSSGGTFVVSYSDAAILVYDTRTGEEIGSMASLETYDGTSATSVNAVVATTVGLEQPQGDEDVSGSGTLGGPTGGGRRSMAGSGVEGVIISGHEDQFIRFFDANSGQCTYNMLAHPAAISGLSLSPDGRELVSAGHDASLRFWSLEKRSCTQEITSHRIMRGEGVCSVVWSQDGRWVVSGGGDGVVKVFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSW0</accession>
    <name>A0ABR3YSW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="27791" checksum="7AD7F130E7FD419E" modified="2025-10-08" version="1">MKADSLHAGAALLAGLAAAKQPNILFILADDVHAPVAPHGDVHFPSGHGEDSFQSARATRYGYGAASHAAPNNTYKGLRVIGDTYNLDYSVWCTNETELYNLVKDPYEVRNLQDANGRHATQANALRIAGHSLDQIMSRLDALLVVLKTFVREMCREPRRALHPQGDVTSLHDSLAPHFDAFYASKPRVHFTKCELGYIAESEGPNYVNQFGGGIHHGYIPSNAKAVPRSDAAASGYDCKAVTDLGPQHRISMWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT44</accession>
    <name>A0ABR3YT44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SWI5-dependent HO expression protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42173" checksum="371B6F71772AC749" modified="2025-10-08" version="1">MASYTTERPSSPSFAPFTLKPLPLDLVGGVPSSIGYDTMPSSVADGTNGDAHDTTNGVDGQPGPSPVLPPPSILPPAIGAFPGADPASPVDFSNLSPEVVARLEHIVNNFRSNHANGFANGSSPSTLSQSSIPSLLQTTPSSVVPARDDTYLLIEKRRHEDTKVLLANAEKRIEQLHMQLDDHNGILEDFRIDNRDLKDQVEESALEIDSLQKHIAKLSHVEQQLKLHIDRQQALETHLQIEREGRKAVDDELMLSRRARNNDLLNFEEERKKHATANTVISQQAENIRELQQQLDAANKRVAARDRMLADAEVEKRALQATVFDARHNIEETAAVFGEASLAFNTEVDRLMSTLLSMKLSATPRSMLPSQAPTPSLPPTPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI0</accession>
    <name>A0ABR3YTI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031248">
        <property type="entry name" value="RNF213"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046439">
        <property type="entry name" value="ZF_RZ_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22605:SF16">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22605">
        <property type="entry name" value="RZ-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20173">
        <property type="entry name" value="ZnF_RZ-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51981">
        <property type="entry name" value="ZF_RZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0391">Immunity</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RZ-type" evidence="7">
        <location>
            <begin position="429"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="511" mass="56128" checksum="650A9A86A66C513E" modified="2025-10-08" version="1">MFYQEVDFIVMSTYRDTNLDEDPCIFPICGHILAMSSMDGIMDMAKHYTMETSDSGLPYPVALAASSSPFDMKEVKVCPHCRGSLRDVARYGRIVRRAVLDESTKRFINWARQKHGDLAQKLMAHKSQLEDDKAGKLYLMRHRGTDDGKGKTKKSFAIKTRSNLVAELLMSTDASRHESLLVTRNEIARFCAQVTADEQPFRRVADLVQFAHNRRAASSTEGGSDFHFDESVIQIGSSLHATVLLMRFDIHALECAVYALEKLTEVDKVHARIRGHRIIAQDSVDSFTAAIQIIAKAFKADRFIALLNEFDATTAAAKLAKYTQQEVAGAICSAHLCIVLWKLADFAGDDDNGAKDKETAVPGLTTNEAVGSVSSSTALSRNKLKELAGRYVDTARKLLEASPSSTDLFGTEVDHLETALTNFVEYQPVTAAEMQAVYQAMAAKFHGTGHWYTCANGHPFTVGECGMPMEQTRCPECGATVGGLNHSPAEGVARAVDIERLGQGMETLAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTS3</accession>
    <name>A0ABR3YTS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF1">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN RRT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="302" mass="33756" checksum="25FBD478F230D119" modified="2025-10-08" version="1">MPDDRWTISAPPPFHRAGGYLQRAGHAASFPMRGIYYFVRHREFHPLFAGRLLPLALISFLVYLILFTFAFLPQFAFLAIFHGWGAWVNAVFLVLGEGLVITQGLFEGFFVDEARVDVFDATLIKKGYADLVSPHRIVDASAPTAVRMLGKPTVAAAYQPWSIIQIVELILCLPLNLVPLVGTPAFIMITGSRLGRLSQYRWYKLRGLTRKERKAEISRRGWDYLWFGTVAMLLELVPVLSFFFLLTSAAGSALWAAELEGQRRQAEGLEDGRGAPIVPGNEHDGDILAAEDDPPHYEDNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY0</accession>
    <name>A0ABR3YTY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle subunit SRP14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Signal recognition particle 14 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007358</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SRP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="131" mass="14416" checksum="664A81639F1B2ECB" modified="2025-10-08" version="1">MGYLDNDEFFSRLAELFHTQKGKDHGAIYLSQRRLARGEKGVSGTGPDGNPDVEVLEPQPLIIRATNGKSKKHRKDKIRLTTTVGPDALEGFYARYAETCKAGMTLLKPRDKSKKKAKAKKKKAATTTPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY9</accession>
    <name>A0ABR3YTY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_007473</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="311"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="618" mass="66917" checksum="822D4C8B2B27C174" modified="2025-10-08" version="1">MSASQPTETPVAEAAPAAAPSAAAAAGDAAPAAEGEGEGPSKKAAKKAEAKAKKEALKAQRAAERAAAEAAAKAAGGGAGGEEVDLATDNYGDVAAFATKGGLRFTDGAAPVALPQLGEEHVDKPVRLYGWIQNSRMQGAKMCFVELREQQDWTIQGVLAATKPDVKENIVSRAMVKWAGSRSFESCVVVEAIVRRAPEPIKSCKVSGFELHITKFFVVAAAPQILGLTLASANKAVNNFDDTAGGEAEAEAEAEAAKKATEAVTEGVKNLDVAAENTISGAALGTHLDNIVMHKRAPVQQAIANVRYETEKLFREYLDARGFKGFQAPGLIDAASEGGANVFQLTYFGKPAFLAQSPQFYKQYEIAGGRKRVFCVGPVYRAENSNTPRHMTEFTGLDMEMEIQESYHEVLHMLEGVLLHIFRGLKERCAEDIETVRTVYPSTDFLLPEPGKEVRLTFAEGQKLLREHGPEIYRNVSDDEDMSTPQEKALGELVRQKFNTEFYVLDKFPQGARPFYTMEDPANSDVCNAYDFFMRGQEILSGGQRIHEAGLLEARMRRKGLDPKSEGLKEYVDVFRQAGVPPHGGGGIGLDRVVAFFLNLPSVQLAAYYPRTPKRLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUH3</accession>
    <name>A0ABR3YUH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoglycolate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007628</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07505">
        <property type="entry name" value="HAD_BPGM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051600">
        <property type="entry name" value="Beta-PGM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46193">
        <property type="entry name" value="6-PHOSPHOGLUCONATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46193:SF18">
        <property type="entry name" value="HEXITOL PHOSPHATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="26771" checksum="5A523E6E0B823761" modified="2025-10-08" version="1">MAINTILFDCDNTLVLSEELAFEGCADLLNEICTTKGVSPLPNFTGSTLITEFVGQNFRGMLTSLQSRYGFPLTPDETNTYVLREEDVVIAKLRQALKPCVGVEPQLETLKADDKYLLAVVSSSALRRVKASLEVVKFDRFFAGDHVYSAATSLPTPTSKPDPAIYLHALKELGKTASEAVAVEDSRSGTLSATRAQIKTIGYVGPYPEDKKAEMEKVLRDAGAQVIMQSWDEFPAKLEEIEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ1</accession>
    <name>A0ABR3YUQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007453</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF1">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="300" mass="30817" checksum="DE37F7931F9E81D6" modified="2025-10-08" version="1">MDPTSAEPPSRSLKGRVAVVTGAGCIGEGIGNGRAISILLADDGCDVVCVDMNLAWAQKTADKVNKKADGSARAGRAVAFQGNVTLEKDCEAAVQHALDTFGRLDILVNNVGVAGASGTAVDVDMEKWAATLDINVSSMVRMAKYAVPAMERNGLEEGNGVIINMGSVAGLRGGTPHLLYPTSKGAVVNMTRAMAAHHASAGIRVNCVCPGMLYTPMMYAAPAADASDATKVIMSEEARAARKARSLLGTEGTAWDCACAVVFLSSDHARWITGAIIPVDAGVTAAVGIGMPKSASVNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV34</accession>
    <name>A0ABR3YV34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GEF1</name>
        <name evidence="12" type="ORF">Sste5346_007194</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF9">
        <property type="entry name" value="ANION_PROTON EXCHANGE TRANSPORTER GEF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="764"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="736"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="880"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="896"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="910" mass="98192" checksum="386B88C73F18F1CD" modified="2025-10-08" version="1">MASRSSSFMSSTAMGDAGGGAAGSVGSGLHVRRPSVSSRLSFAVSTAERGEHDESTPAAAAEHQRIEEEIAEIKRYEDFTTIDWVQDAAREQLRRKARRRHNANLYDHGQVGWRHKLYESYDAAQGWIVVTLIGVAIGLNAAFLNIITEWLSDIKLGYCTTAFYLNENFCCWGEDNGCADWHRWTGFEPANYVLYLIFATAFAFTSAILVRSYAPYAAGSGISEIKCIIAGFTMKGFLGFGTLAIKSVALPLAIASGLSVGKEGPSVHYAVCTGNVISRMFAKYRRNASKTREILCACAAAGVAVAFGSPIGGVLFSLEEMASYFPLKTLWRSYFCALVATAVLAAMNPFRTGQLVMFQVHYDRSWHFFETVIYIIIGIFGGLYGAFVIKWNLRVQAFRKKYLSQHAVLEATLLAAATAIVCYPNVFLRIDMTESMEILFLECEGAEDYQGLCEAPNRLWSIASLVVATLLRTFLVIISYGCKVPAGIFVPSMAIGASFGRMVGIIVQAIHEAYPSSVFFAACEPDVPCITPGTYAFLGAAAALSGIMHLTVSVVVIMFELTGALTYILPTMIVVGVTKAVSDLFGKGGIADRMIWFSGFPFLDNKEEHNFGVPVSQAMNSDVTALPAAGMTLAAVDRLLAQGKYQGYPVVEDAETHVLVGYVGRTELRYAVDRFRRNAGPLNPDTRCVLLPPAELAAAAANSGPAAAAAVGDDALLTAPMTPALTVFPDMAAVNTSANSGRRSPGASPAHPPPTTAVDFSRYVDRTPVTVHPRLPLETVMELFRKIGPRVILIEHHGKLTGLVTVKDCLKYQFKAEAAENTRTAGTNGTDENGNGAENQQEQLWHGMLWLAGWVADRVSRLTGGRIQLGSGHNGYYDGSGGNGNRGSGDHAILDGTEDVDDEGVELDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV79</accession>
    <name>A0ABR3YV79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1038"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1104" mass="119849" checksum="BDA02215D4D85F43" modified="2025-10-08" version="1">MAPPGPPMPVPSKAAIRALRGLVLGTTCTLALVTEDRRRRINAARSAIRNGDRIRSARRYHPGGSAFAIALEEDSLSVEPGVINWKAPTRQGQTRTQTTTASTSSTSSQPEPQPPIFAYPPPAGERIQRHIPSLAHQAEEYRARARLGKLVDSSIIPIGRVSQVSPAQPAVDLSEAMADQAKALAKPMKTEAELEAAVRTLMNTWPIIDAASDQTALGKTSAELCQFCQRAGRMDLAQAVLQLAVKFGQLDEATYFAHDPLPVVRSLVPLNALKGELTDPAMEEDGSGARRAAFVKRLEDAASLFLPTFTAPHIPDFPLAKIVTIGKKLLKCAFAAFHHELINTIYTSIAKYPGDITEFTQWYNEKMQSTNDHALLVSSFVARPPSAGSLSKTVFLEIGGRVAEASRLSHYTQAGAILDTLIDISAPATYRLRTAWGTDLLYGEWQKNKDYKEIKRLFAKLIGPRKEEFRTPTIYHVNGVYRVMVQIAFEADKPAEAKALFDELLAFQPTADEDIRLTGLFALAKAKAGDWQGVQDDFQKAADAAANKGGLNARDTERVFVPIAKEYIRTHTIGETEDFLKQYIDEVGVPIGRNMVTLLANEYGALREVRSFVGWLDYCVQAGFAVDAAFSNAILHNCRKHWKMGFRELRIMYRKLRLLSPNFEDKVTQTIMTHAAISDARSIGRPSPSTAIKSRVVSLRMNNNNTPHAVANMATLAAAAQHNSSSYASPLSARHLLDEHDLYVAMKHAFASGSPTKAVRMYKHAVRGGMPPSEKCLKLAVAAAVKSEQSIGSTSSPLPTKRVPDFDVAVDLLKTAHMAGQDIDGATAYLAIAYIDALGSRKAATTAKSRKSNAKASVAAAVKSVLLRLDACDVQMTDLALNRAAFHMFKAGHMSGAIALAMSAANSPVGGGRPGYNVWNFSVLIAAHARLADADGIRAATEGAAASGVLRELMGYRVLKQSRGRLRNRLLEHELSATVHGPKHGHATPEAHKVHGDDLNAALQAVEDAINQAREARQQLSKERRALEAATISIMQQAALDAGHPPVDFDKRKKSRQKQHEDISSTRGSVSSGSSWDLLDMPVDQDGQLIEAEQPRAAAAVAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVG7</accession>
    <name>A0ABR3YVG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="77" mass="8035" checksum="131156F18112D796" modified="2025-10-08" version="1">MAPSKSGRRRRAGAAVDKKLLDVFVFVFGNGENGENGELGFGAGPRRTEATVPQLNLFLSSAGGPRQAAIPTFNTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN6</accession>
    <name>A0ABR3YVN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="270" mass="29503" checksum="F0E071EAF72C98D3" modified="2025-10-08" version="1">MSHQNGQNGSSVLDEEKGLNRTQTAVTMSPEMFEKLYLTPKVPHVGDNIKRFANPTPLGFIGFVIASFSFSMILMGWGGASGATPIVGIFIFGAMLLVFGFIFEWIMGNFFSMISMGLFATFWLSFALLQLPTLDLSAPYITEADPTGTGAKAFNAGLALYLIVWGFIIFSFAFFSLKTNVAFASIYILLIAFAFVMSGCYWRLANADVPGAITLQKTGGAILFAVAVIGWYLTMVIVAGEMRVNLPLPVGDLSRFWPDSNKDLADEKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVZ5</accession>
    <name>A0ABR3YVZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SUI2</name>
        <name evidence="6" type="ORF">Sste5346_007191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="17"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="309" mass="35195" checksum="3EC2112B3865DFD2" modified="2025-10-08" version="1">MSYSNCRFYEEKYPEIDSYVMVNVRQIADMGAYVKLLEYDDIDGMILLSELSRRRIRSIQKLIRVGRNECVVVLRVDKEKGYIDLSKRRVSTEDVKKCEERYNKSKMVHSILRHVAEKTLTPIESLYETIGWPLNKQYGHSLDAFKLSITNPDVWKDITFPSAPVEEELKSYIGKRLTPQPTKVRADVEVTCFSYEGIEAIKKALRTAEAENTEDNKVKVRLVSPPLYVLTSTCLDKNTGISRLTKAIEDVRTVIEASGGKLVVKMEPKAVTESDDAELQALMEKRERENAEVSGDDSQSESDDLPEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW63</accession>
    <name>A0ABR3YW63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14 15">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="3 14 15">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">MVD1</name>
        <name evidence="18" type="ORF">Sste5346_006914</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:23732"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.33"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:23733"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 15">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="3 14 15"/>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053859">
        <property type="entry name" value="MVD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977:SF3">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22700">
        <property type="entry name" value="MVD-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 15" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-1207">Sterol metabolism</keyword>
    <feature type="domain" description="Diphosphomevalonate decarboxylase-like N-terminal" evidence="17">
        <location>
            <begin position="13"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Mvd1 C-terminal" evidence="16">
        <location>
            <begin position="199"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR015950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1892629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="394" mass="41251" checksum="F942A660ED90E7CD" modified="2025-10-08" version="1">MADTKVYRATTTAPVNIAVVKYWGKRDPKLNLPTNSSLSVTLAQSDLRTLTTATCSAAFQGQSDSLLLNGEPSDISGARTQACFRALRERRSALEAADPSLPKLASLPLRIVTENNFPTAAGLASSAAGFAALVRAIADLYELPDSPSQLSLIARQGSGSACRSVFGGYVAWRMGEKEDGTDSLAEQVAPASAWPQMRAVVLVVSAAKKGVSSSSGMQQTVATSGLFQERIRTVVPDNIAKMEKAIAAQDFAAFAEVTMRDSNSFHATCADTYPPIYYMNDVSRAAVRAVEAINAKAGRTVAAYTFDAGPNAVVYYLEQDADIVLGTFSSILGAGVDGWKGGEAPSTAAAAEVDATVASTLKTGVSRVISTGVGEGPIKSEEHLVGEDGEPVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWS8</accession>
    <name>A0ABR3YWS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046736305" description="Glycoside hydrolase family 5 domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="79"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="47163" checksum="81033452174416F7" modified="2025-10-08" version="1">MHHFGMMRLLRFIGLAGLAVANPVTFDVDSVDSTSAAWPNGPLVTSGRWIHDAAGSNVTYAGANWPGAADTMLPEGLQFQSIDAIVDKIKGIGMNAVRLTYAIQMIDEIYDNGGKDVTIEKALTQALGVTNGPKVLAQIIKNNPSFSASTTRLQVFDAVAASLNKAHIYVHLDNHISKAEWCCSTTDGNAWWGDTDFDTTKWARGLSYMATHGKAWPNLVSMSLRNEPRSPDDKSAAATASKKTYNWQGWYKFVRQGADAIHQANPDVLIFLSGLGYDTDLSAVTKGSALSPGNDRFSLSDFSGYSNKIVLELHNYQNSASSCSSLESGLTNAGFSAMSSGSGLQIPVVMTEFGFMMDASTYKGVYATCLAKFLPNLHAGWTIWVLSGSYYIRSGKQDFEETWGLLNHDWSAWRNPTYVKEQLEPMIKATLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWZ3</accession>
    <name>A0ABR3YWZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphopantothenate--cysteine ligase cab2</fullName>
            <ecNumber evidence="2">6.3.2.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CAB2</name>
        <name evidence="2" type="ORF">Sste5346_006791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.51" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="41021" checksum="6B018F397023C19A" modified="2025-10-08" version="1">MAASTTTAATSGGATQSDEDRYFSTNPPPKDLEQHMALVEAFVDKHAKANRRIVLVTSGGTTVPLEKQTVRFIDNFSAGTRGATSAEYFLDDKADYAVIFLHRQFSLQPYSRHYSHATNSFLDFLTEDENGHGVRSRDEDADSMLSVWRRYRNAKDRLLALPFVTITDYLFELRAISRIMHRLGPNGLLYLAAAVSDFFLPPERMAEHKIQSTDINADKSGGKLPGSFALDDDEETFDNFDSSPKVPRSKSLVIDLDPVPKFLKSLVDNWSPESMMISFKLETDPDLLIGKAKGALERYQHHLVIGNILATRKQEVVFVTPKDVDWVRLSAAEAKDNVEIETLIVPRVISLHEEHIQHNKASKAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX56</accession>
    <name>A0ABR3YX56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_006651</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="13">
        <location>
            <begin position="121"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="14">
        <location>
            <begin position="429"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="15">
        <location>
            <begin position="535"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1892971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="638" mass="71865" checksum="27DF29615C58B291" modified="2025-10-08" version="1">MKTDDLKALPAKLVGDFRAVEPSLAALDKHLVLRSYLDGYTLSDVDSKIWVALAENRAAVSFVRRGTLVNLKRWFLFVEDRHPEIQDSVKAASAARQAKVAAASRAGGSYNMSLKDADKGVVTRFLPEPSGYLHIGHAKAALLSDYFARQYNGTLKLRLDDTNPSKEKEEFQDAIIEDLRLMGIRPDTLSYTSDYFDYLYDMALRLIKEGHAYADDTDQETMRDQRMKGIASKHRERPIEETLQIFNEEMKNATATGAKHCIRAKISVDDNNKTLRDPVIYRVNVETAHHRTGTTWKMYPTYDFACPVIDSHEGITHAMRSTEYTDRNAQYQWFLNTLKLRQVHMFDFARMNFIRTFLSKRKLAKLVDTGRVWGWDDPRMPTIRGVRRRGMTIPALRDFILKQGPSRSVTTMEWGVFWAANKKEIDPVAPRHTVISAKDAVKVSVTGADAPTTPTSVEKPLHPKNKDVGTKQVVFSNELLLDQADLKLMKDGEEITLMSWGNAIVKDIQTGADGVVTGATFELNLAGDVKKTEKKVTWLSTAGQTLVNGEAWDFDYLLTKNTLTDDDVLEDCLNPVTATEENVLGGANMKDLKKDDIIQLERRGFYRVDKGLNDWAEGEAGEKGPRIVMFLIPSGKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXS4</accession>
    <name>A0ABR3YXS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GEF2</name>
        <name evidence="12" type="ORF">Sste5346_006585</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF6">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="614"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="682"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="709"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="777"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="925"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="968"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1006" mass="107241" checksum="FC0F5BBFAEC30FD5" modified="2025-10-08" version="1">MDPLIPTAAGRNGGGSGSGSGGSDAGRASPYQNGGQNGGQNGGQNGGAIDLLGNDSQASGPYSGDNHDDPDHDNHDSHNNDVDTSDVDEHTISAAELNGPMSFKRRQKQTSFLPRSARSLLSTFGMGTTTTSSSNAHNSHTLYGHEATGPIGLGSAGNNEAFETQGVYGGGGGHNGEPSNINVNLHSNGGSNGKNSIGLPHVVDWYSEGLGRRVGYEDLTAIDWIFEYNKERQRQRTLVSGTSGLLGLVRRLLDAGQVWVVLVLTGLAAGTLAAAIDVASDWLGDLKTGYCASGGTDGGAFYLNHGFCCMGYDEGAKCEGWRPWAVALGLSASSAVGKWFLEYLFFVVLSVTCAVCAALLVKEYAIYAKHSGIPEIKTMLGGFVIRRFLGGWTLLTKSLGLCLAVASGMWLGKEGPFVHVACCCANLFIKLFPSINNNEARRREVLSAASASGISVAFGSPIGGVLFSLETLSYYFPDKTMWQSFVCAMTAAFVLQALDPFRSGKLVLYQVKYSTGWHAFELIPFALLGILGGVYGGLFIKVNMWIARWKKANAGWLPGPVTQVALVALLTALINYPNLYMRAQLSELVSNIFSECSPQLDDVFGLCKTGAATAATIVLLLFAAVLGFFLAAITFGLQLPAGIILPSMAIGALTGRAVGIVMEIWQTNHPNFLPFQSCEQDLSCVTPGTYAIVGAAAALTGVTRVTVSIVVIVFELTGALTYVLPIMVAVMLSKWVGDAFSRRGIYEAWIHFNEYPYLDNSEEMQFQIPDVPASQVMTRIEDLVVLTATGHTVASLRRILDAHPYRGFPIVSDPRDAILLGYISRAELDYTLQAAVKPPRSLPPDETEAFFSHQPLADPRTTLDLRPWMDQTPLTLPSRSGLHFVVNYFQKLGLRYVLFSDRGVLQGLLTKKDVWYVLNGAEESRRSGEDDGLRANASLGRRGDDNSIGNNGGGGAGAGFIAGGAAAGESGRLREDGPGMHQGLLHDGADMLDDPLSPGPDQESIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYF0</accession>
    <name>A0ABR3YYF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SEC21</name>
        <name evidence="16" type="ORF">Sste5346_006768</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Oligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Golgi apparatus membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasmic vesicle</location>
            <location evidence="11">COPI-coated vesicle membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the COPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032154">
        <property type="entry name" value="Coatomer_g_Cpla"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16381">
        <property type="entry name" value="Coatomer_g_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037093">
        <property type="entry name" value="Coatomer_gamma_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="14">
        <location>
            <begin position="650"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer subunit gamma C-terminal" evidence="15">
        <location>
            <begin position="801"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="608"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="617"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR037093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1892875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="916" mass="100858" checksum="039E0E30D710A87D" modified="2025-10-08" version="1">MNYGKRDEDADGSLVRVDRTQVFQEARLFNRSPIQPRQCRILLTKIALLLYTGERFPTTEATELFFGISKLFQNKDASLRQMVHLVIKELAHSAEDIIMVTSTIMKDTGGSGDYIYRPNAIRALCRIIDATTVQSIERVIKTAIVDRSPSVSSAALISSYHLLPIARDVVRRWQSETQEAAANTKSSGGFSLGFSSSNAMPVNSSSMTQYHAIGLLYQMRMHDKMALVKMVKQFGVAGAVKSPAAVVLLVRLAAQLAEEDPTLRPSMVTLLDGWLRHKSEMVNFEAAKAICDLRDVTDAEVSQAVHVLQLFLTSPRAVTKFAALRILHNFASFKPQAVHVCNPDIELLISNSNRSIATFAITTLLKTGNEASVDRLMKQISGFMSEITDEFKITIVEAIRTLCLKFPSKQAGMLTFLSGILRDEGGYEFKRAVVESMFDLIKFVPDSKEDALAHLCEFIEDCEFTKLAVRILHLLGIEGPKTSQPTKYIRYIYNRVVLENAIVRAAAVTALAKFGVAQKDPEVKKSVQVLLSRCLDDVDDEVRDRATLSLRLMEEPDELSTRFVKNENMYSLSYFEHQLITYVTADDKETFAAPFDISTIPVVTREQADAEDRTKKLTATAPTLKAPKLGPTKTAATGAEAAATASGQAQKYAQELLQIPEMKEFGAVLKSSPVIELTEAETEYVVSVVKHIFKEHIVLQYEVKNTLPDTVLENVSVVATPSDDEEVEEVFILQAERLATDEPGKVYVALRKVGGADALPTSNFSNVLKFTSKEIDPTTGEPEDTGYDDEYEVSEFELAGSDYVIPTFASNFAHLWEQIGASGEESEETLQLGGVKSIVDATEQLAKTLSLQPLEGTDIPQSQTTHTLKLLGKTVNGGRVVANVRMAYSSKSGVTTKVTVRSEEEGVSALIVAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYI7</accession>
    <name>A0ABR3YYI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325886" description="Heme peroxidase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1115"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1130"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1318" mass="146114" checksum="AA7CFB04ED3B42CF" modified="2025-10-08" version="1">MRANLALLALASSSTVTALDTRYHATTNKNGDYVADPSRPTHDDDRPGNHFSNWFHHIVKHGRAGDDLKDFFLGGHVPKNASFQTIQDSLNLTDRQPVAGELHNQKHISPSKPHPGRGAPHHWDALEAKKLFKHLNFELDETCIADKANWWYRTYDGSCNWLKADEAGQGRYGQAKSRDFDQHYYADGISEPREGPNPRAVSNAFFRRNSTIYYEHTPLLLGLIEFIIHDVTWSQDSSTEFIDVEMPEDETEFAPNTTLRVWRAAAAPGTGTSPQNPRENMNHATTWIDVSSLYGSTRSVGEALRTKEGGRLKTQEVLGGTKWKSPESKKTSYLPFDTMGVPVRSPPGMDPATLFAGGDPRTNEDWVMLAVHNLLLREHNRLAGILADKRPDMDDEQLYQTTRLLMSAKFQLIGNAYQMAYFEKDMPWPQDDGFPLFREIHGEDWLQMNPANTYPWPLAMKAGRPTVVSAEMAVVYRFHEFIVNEFPIVDAAGTTLHNQSLFDTGFDAKGFIGAGLENILRGVVSTTIPNFKSGVDESFRSAGKYRGSPFDIVTWSIVHEREQGLPTFNNYFRAYNAQKPHVLVPIRERFEDFTTVPEHLAALKKLYKSPDEVDLVVGCQLDETMFPATSVPRSSLIVSLFNLISMGNADRFSVGYAAMRCWLVDKPWDCHPSNALEDLLWKPVAKEGFPDFRFYDDFWMEELDFQAHGQNLLWRIVTENTDINCLQQHPLFPADPKTNPILCVQPATKVNWAVIGSTATEVTLSLVKEHYVAIIITVLALVATVYLVKYAMAREDGYPHVLYGWPILGEGYAFQQNAKAVLLKGLEKLGNRAGPSKVFGMHLGPQTHYLLTQPEDLQMMLDDNPYSVHFNLDKFFAGLGAPIFLGKDVFSINLHATLIRTHLANPDTVRQFGPTIASAAERYLRDNPLAPADGSSVVHQTLSDWMDRFSTSVSARCMLGADADQHPELIDLFLKFNTTVDAVMQLSSVLPPFLNFIPKIQISRSYKQFSKIFLPIIQRRRANPASSQDGNGQGGLLDFMPFILEAVDDDELASNLVAISVWIGLRNLQVSVTSTLLDMINEPGLADQVSASLKGATLETLDTFSFAAKATNGVTNGNSKANGKADGKSNGKANGTNGKANGDNGHSNGAANGFVPTPGGGTSGSPWAFLRSAVLESIRLCGTITGPARIIAATKPLPLKSDPSLKLPPGKVATLSTWYTHRQTASFGPDAAQYRADRFVDSSPAIGSVRNISFGLQGPRICPGQWYVQEAICIMIQQLLEGYKFAPTVMRVGDADKYIYHAGVVTRKEVPVAVTRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ12</accession>
    <name>A0ABR3YZ12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045125314" evidence="3">
        <location>
            <begin position="17"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="707"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="814" mass="87315" checksum="05FBF6CD43751C9E" modified="2025-10-08" version="1">MHGLLKAGLLLAPALARGVGATASPQDDKPSAFISLDVPDAGLENGTPFLSFRLDVLDSLNACGSTNVTINGEALPENGQLSLPLVPDFESIHTTTDADKISKKDTPSAVVSWETDCVSWGGQDREQMMRLRIVSVNGVAVKDDAAKDPTTVRFRQTAPARIVLVENAASAFQFNDNYFKAPTTASAPTTPADKKAVDNSNGETEEETDEFENDDTDYSDADSEADAADLVAWENSLIMMHRSVALLFHDIRVRERYVLERFGPDASPIVDGHRKHGFGKHGGPCSDVTAFIGSVWHKVAGTAKSLYGELIANTFGDGGGPHGHWGPPRGFHDGPPHGPPHGPHGPHGSHGPHGPPPFMFRPYCFPEDGRVGPPPPPPPPPSFLFNCPSAFPPPPPGEGLPPPPPPPAEGFPPPPPGPPGLPPKHPHGPPPPGPPSELNGLPPPRHGGPHEGHHHGGPGGPGGPEGPFWVGMSGGDRFDKRPSEGGEFRGRKMHGHGPDGPPANVWKHGHHGHRGPPGSFPFGRAPVAKMVAFFGLVIVLLFVFARHCRNRRMEERMRRRANRPRGLRGFAARFQEFTEEVQERHERRQARRERRRKQKKSVRGFFRNVRCLLFGGDRGDEKLDDANTTASERTGLRTPADGHIVTSTPPSRQRSPAPSLEDEIAEFRVAADVVGQMIAAEEGRLAIAQTAESRRRQDEDLEAAMRSVSPVSRSATSPAPAPVSPAPAPVTPPPAPAVAPYHQPPPPPPPPPSMANSSSVYGGYGRRDAAGIDSDYDDVESLPPAYSPDDYQYVNLVEASVVADGFQYRPGSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ42</accession>
    <name>A0ABR3YZ42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BTN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BTN1</name>
        <name evidence="10" type="ORF">Sste5346_006474</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the battenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018460">
        <property type="entry name" value="Battenin_disease_Cln3_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015974">
        <property type="entry name" value="CLN3_BTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="482" mass="51567" checksum="1653EF4FB09986BD" modified="2025-10-08" version="1">MSRSPSSSGLLLPLPGSPASSWALYRAHLKALVSGRTSVFISFWLFGLINNVLYVIILSAAQDLVGTLPKGVVLLADVLPSFATKLVAPYFIHRVPYAARIPVFVALSSAGMLLVATTPATASVAVKLTGVVLASLSSGGGELSFLGLTHYYGPLSLAAWGSGTGAAGLVGAGLYVLLTDWLGFSVRASLLASAVLPIVMLVTFFGLLPRGPMRATLGGTGLPKEQQRYTLVPAHGEHDGEDDGDVEHDHDHDRFAPAAGPSATAYAAANVADDDEETVLAAHPQVPPPTASFQANLRRARALFFPYMLPLLLVYIAEYTINQGVAPTLLFPLESSPFTEYRSFYPFYGFLYQLGVFISRSSTPFYRIHRLYLPSLLQVVNLAILTAQALYFDSFLPSVYVVFAIVFWEGLLGGAVYVNTFAEIMETVPAADREFSLGATSVSDSGGICVAGLLGMAMEVGLCNWQVQHGRDWCRQIKPSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZE2</accession>
    <name>A0ABR3YZE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Allantoin permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="61545" checksum="DCEC470CC47ED139" modified="2025-10-08" version="1">MSILTKLDNALRTKESIFHEQQEDTKKWGNEDLDPTPPSARLWTHWNYFAFFWAVSFNPIAWNTGSSLISLGLLWWQATLAAITATMITGTMLMLNSRGPSVYHIGYPVYLRLSTGMYGSLFFVFIRGIVAIFYFGTQSYYAGQLMSVLLRCAFGSKWTNVPNHLPKSAGNTTQGITAFFVFWFIQLGFMLIHPSRARWLYTIKSVLAPPVLLATFAFIVGKTHGLGDTHALQTKVLTSSGVAWAFLTGVNSVSGSIIPEVTSNPDLARYAKHPRNTTWPQWIGLVIAKSLCTFLGIASSSAVKTLWGTAYWNIWDLYNAILDHYWHAGARTAVFLACTIQILAVVATNLASNALPVGSDLSGLFPRYFNIVRGQVLCAVLALATVPWKIVASAASFLTFLGSYVCFLSPLVAIMIVDYFVIRKGNVHIPSLYNGAPSSPYWYNGGFNIRAFVAWAIGVAVVINGLAGSFHTNYNAGSKHLYSLGLVLSFTVGGLLYYVFNKIWPINIYPAYHSGEDAKTFETMKQSDGYFADDDVIITGTDITPMQQEESVLKDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZG3</accession>
    <name>A0ABR3YZG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF74">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="502" mass="55003" checksum="32186062A32601D9" modified="2025-10-08" version="1">MNSPDTKPDPVEMVEAANAKEALDVEPFSPEEERRFVRKIDFWIIPLMMFTYFLQSYDKGIMSAATQFDFNTDLGLTKIIGYTSTGTAITNNQKYANASMMFYVGYLIGTYPMMFLTQHFGVTRVISFAVFAWGAVVMATSACSNYAGIMVARLFLGIMESAVAPAFTVLVTFWWTREEQALRTSMWYSSVGLATMLSPLINYGIGNGVHGALASWKYMFLIIGAITVLWSFVLFFFLPDSPLNCSRLSEDEKALAARRLARNNAGTINRHFNAAQCREAFLDYKTYSAALIILLTGVPSGAIGTFGTIVINGFGFDHFASLALTSPIGAITALSILFAGYVTRRWLGLRHILIAVLALISITGTLFCWFGPRSNRGFLFAGVFLLAVQVAAGGQAVSLAASNTSGHTKKATVSASTFLGYCIGNIIGPLIFGASPGPLYHAGFLGSFICLVCVVVIAIVTYILLRMENRKRDRLAMAGGVRHHTIDEDLTDKQNEDFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP8</accession>
    <name>A0ABR3YZP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sister chromatid cohesion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SCC2</name>
        <name evidence="4" type="ORF">Sste5346_006635</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCC2/Nipped-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23958">
        <property type="entry name" value="SCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="3">
        <location>
            <begin position="1590"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="736"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1548"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1925"/>
            <end position="1998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1925"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1953"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1988"/>
            <end position="1998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1998" mass="217460" checksum="34A7525400A9A942" modified="2025-10-08" version="1">MADPSILLGEHQEPQQNGFQNGSGGIDPSMLLLNPNPTPSPLPPPSSQLPKAEPLAISISAQSSSSGNTISPSALHQPPMSAPPPPPSSSGPQKFMRPFAFGEALPYSPFTSISPLETRIIPIPTLAAKAASNELSQLVSQQEFNTLNNNAFGQPASLTERSVDDLHQLLANGRVPQFNFKPLPRASGGESNGATSSDPSTHNPASNLKPITKAVFEKANIPFRYPSPESPSQPPPTNGNTPKTTAVPTTKSTPTKKSGTSSKAKESAVGNGTAVTSNGVDASSASASLNAQAHAKNNMAKIEISIPSLPPSYTAEAIIVDESPIITSPQTNGLSAPIKSESITVAAPTVPKETPVPVPAVPRKETPIKPPVPGQPPQDTKESITIDLAAAPNFNPQDYQVVADLPDDNTQDFFSDLDQRQRAEAAFQELLRLFQDIFEAEMNVNKQPGNVALISLTTDDEPTLTDNALRKAQSTIHKAITLGCFADIPIDDLLHLQRLCDGALRHALSLDLKLSSEATESEIDEWVVQLRIADTGLRAARLSLKIMSGGREDKQLYSENVIQSSVDLFKNVMDNAVVPIAELRSSGPLERRFKQLSSYKKAISPLFMAAQRLFSGMTTLVQAIDLSELVINSLEFCASHLIFVENAHTERDSVLGVQAFDGLRLAAMDMLSQIFVKKPMQRRGIFDDILTSLEKLPVGKLSARQFKLADGKSIQPVSALIMRLVQASAGRVAEKEKSSSGIIDEAMDEEEKETEEQNQAPNAPVATISSEEEGAYEHELSIAELTDAASPLNSTAYVHAKYVIKFIVERAQTSSKSADTPYRNLLDLFVEDFTACLETPDWPSAELLLRLLMMAMFKLTENDKIPAPVKNMALEELGVIGAALAKLRSTIHQSANSPENTGPDELDRLLSNLAGAALGDNPPAEEFLAWKGPFSPALEYLEDRSSQDPHLRGAISYTVADWAARVCRLYSTRAEAAAAAAAAAAAAGGDDDENADSAKARDNRVLERQNRDLGRIAYRLRVMIEDGRGMSGNRAFKGVTAAQAKLSYAIVALRSPLGGSFNDIINILAMGMGSDQATVRSKSLKSITEVLETDPSIFDNPASIVGRLIRECCADSSVQVRDSALGLVSRAIILRPNLESTMIKTVIDRFLDSGVGVRKRAIKIARDVYLRNHSKEIRSDIANGLLHRIQDPDEGVRDLARQTIEEVWVTPFADTVAATAAGTETTAEKSSLTEHVILILQTVKNGSITPILDRVFQAILSPTAKAATANFDVCKRFVAVMCDLADNPESDDPSVPSGYEALQLMMIFAKADPRLFTFEQIRLLKSHIVNVKNVKTPQDMATARAVVVIYSRVLPQLSSVMKPFLEEIRSNLLPSVVNVSRTLLDDVMGCIWVVSVLLKDPKPLVRVVISAIRGVVNQEKMTDNDADFDKKAKRFLRYALIVGMAGKHCDFDSEIDTFRGQFPAYNFSSVSKLMVDTLCPISIPPWPLAIRRIALDAMGLICQSWPRNFVEKNVYTSFHIAFKQQDPSLEVKIMQSLKEFLTKEELRSESGSDATKAQKAARNKSASDGDGPGKKRQLTVMGGTNHDDVASATTQRFMGDITRIALGSVSEEAYLAAEILASISRQGLVHPKETGVTMITLETSTMPKMAELAFREHRALHNKYETVLEREYVKAVQTVFQYQRDVINDTRGATTEPFTSKLHYLMDVVKDSKSRNRGRMLEKMCGQIDFEPNKLDVSEDIPHHLEFARFVIENMAFFEFVTVAELQSLVSTMEKIVHTTGVTISHAIEADIFDPSGGGQKETPILPPNPEGGETSTLVPAGPALRPGLDPRRLKQIATGCMVLLCLWEARTFLCRQYGLKRDGNKAKGASRDLTRAPTKVQGITADKFWEEMSNIMKGLDSEALMVARCKGLVELLTVDSDFKLEEDDGNGMDDDDPATPSGGEDDGGLDRGRKRKAGGTPGGRKKRQRSGSQQPRKRGRPRKSAGPEEDADGDFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZW6</accession>
    <name>A0ABR3YZW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460597" description="DUF8021 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="2">
        <location>
            <begin position="158"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="262" mass="27504" checksum="91D6DF3801B8FC24" modified="2025-10-08" version="1">MIKFTALGLALAALAGQALADCSRDTLLAAADAYMAAQITGSVSGSAFQKLLDPAVTYRQNNKAADLATGLLSKPLKLDHNRTTLDTTQCASYTELVSTAGPYVIGTQLRHASATDAASLITSVDIIVATTGDWAFNAAKTLQYITPEDWGTLAESDRSPRALLQAAADAYLDMWSNSTAINAVPWGTPCARTEGSAHVTPSCKSGAPTTGTAAGKNTDRRYVIDETVGSCNVFCAFGGQMPDSHEFRLIAGKLRLVHTITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z066</accession>
    <name>A0ABR3Z066_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="1">FBP aldolase</shortName>
            <ecNumber evidence="1">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="281" mass="30413" checksum="70D5424A290E0209" modified="2025-10-08" version="1">MAILNAARDGGYAVPAICCYNLEAVLATIRAAEAMRSPAMVLLFPWAIEYAGKALVLAAAEAAHTASVPVSLHLDHAQSPDLVRRAADIPAPYNFDSIMCDMSHYEKEENLKLTRELSDYCHARGIASEAEPGRIEGGEDGIASTDAEELEGVLTTAEQALEFVATGIELLAPAIGNVHGEYGPAGINLDYERLQMVNRTVGDKVRLVLHGADPFNLEIFTRCIKAGVTKININKGVNKHYARVQEEMRGKPLTKVIEAGTDAMQKAVEEYMQWFGSAGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z130</accession>
    <name>A0ABR3Z130_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="552" mass="61978" checksum="CFF6F3042373BC2B" modified="2025-10-08" version="1">MAPLDITEDAVIAEETEGLFFIYIVIKPNNSAEWGAPAEAMQKALQATEITDENRELIRTHHPAFACTGPDDVAILFCPPRLGPQHPMWAVSNTNARILGSHAGGIPIHYRPSPDNHPRVYTGPVISVRMRPHYIYDALDPSGVLSNFHLWALQETFPRSCGARFWLSGTMEMLYSNGRDTYNERHDDEICYGPDYQRAVFETLDCRPTQQCSSTAKVDQWSSPMLELPDGTHVRAVPTYPFVRWPGHPFGWRPTDLALGGIDALLNYWWKPPPHRTDGKPYVWTKDRPPTSNTPLGRRVYRSKRGKGHIITHAFDSPRIVRDYPAGYEHDLSFIMVDKTEDHNDLNYAGLPRIDGWANITDALADDAELFVAYGDELKGYTHEKLPPKPAKTRKVVAEGMQYLWDKKTKQQSMALLWRVVPEMPDLREYATPASIKAVVDASTILPDVAGQALYLGKPTDETAKIVVFQNFDAVCNTGVCKYLGTDKNIIKGGFVLPSFVYEKCKVVLDPETEKEGAGRAVDGRGMEGKEGNSHDQNKKELQCNELSHSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z134</accession>
    <name>A0ABR3Z134_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SGF29 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20394">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047287">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="6">
        <location>
            <begin position="392"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="528" mass="59725" checksum="F6E9299FE1EA4C21" modified="2025-10-08" version="1">MRPRKRRRVVSYAESSSSSREAPHEAPPELPDETPTETPNNNTPANMSSRSRAGRAGPNRGSQLGEEYSMWQSLKEELRSFVEQQNIDNAGLRDIIEQDTHMHDASTNGTMDAEAEEKRQEDLFRKGVKNSEVTQPKIHYLIEQLTVLKAVVASNNKEDEHDSASKSGSTPSRSSLLAGGGSSRSAGRAGTREREKERERAEKEQREREREREKADRDKEREKAAEKAERAAQKEKERERTEKAEQRAAEKEKEKAQKEKERDRDRDRDRDRDRDRDRDREREKADKDKIKEERDLEREKERAEKDPYEFEGPGDEMDIEPTSSSTGNGHSRSKGGASSNNGNDRGDRSSHARDSVPPRGGDRDTTSSVKADSVEPQLPGSGSAMSSAAQRSRVMFVKGQDVVFKPKPANLSDTADWFLGKVQQVLGEGKSRRYKVKDEDPDVDPEQRQEYRTSASNMIPLPPPGQDLTELEAGKTVLALYPDSTTFYKAEVMSTNKVTGKVSLRFEGEENSGLLQEVERRFVVEYRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1T7</accession>
    <name>A0ABR3Z1T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028115">
        <property type="entry name" value="DUF4484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018626">
        <property type="entry name" value="LCHN/Anr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053056">
        <property type="entry name" value="Lipid_Metab_Assoc_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153:SF1">
        <property type="entry name" value="DUF4484 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09804">
        <property type="entry name" value="DENND11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14831">
        <property type="entry name" value="DUF4484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4484" evidence="2">
        <location>
            <begin position="487"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="668"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="691"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="779" mass="83831" checksum="1D6B0D77D408A1A0" modified="2025-10-08" version="1">MASTAEPSTPQRESVVPAPTTPAGVLPDKPPIAALFLIEFDVKAGYTIVWKQTTPGLDLSGAVEYKSLPSGLHAVSEDLIYFVHEDPSSSEDAGSSSSSTPSSDSTGYAGLSAFVNLPTDEAGARNARMIAVGVLVPRSYGRLGRAWRHAAALMDMARKLAADSKQVPLLEAYWHNNNNSSINVTSPTSDIDRPLLQITDSPLGSPALPVPPPMGYRPQPTLATPSNSNSNSKHTRNRSASDGTALLLPPGHRLSPHHPAWSLTTLLDTFGPLIFPIYRAALLRKRVLISTHAPVREVNNFVYNISVLANVPISALDLLEPSAVSHQRIRPLFTIGVNDITFLMDDLAASKRAAREAAEAEGGNVDPNTKLPYVGPGWIACTTDSILAMKNELWDVLITMPPPAGAHRASSLSHLAPSSSNSRNNKSKKVWPTVEIAKGVPLKATQRDLRRYKALVAGLERLAGRAPSASEAEKKNAQLADATEPIVEPVTWAALAYHGFMWWASAGEQSRSEETDETIHDAQLLADIVPPRPQAISSDSHASSSANLLDSVSSLTARRVPADDENSNDDDDNDDEGEERARLELAIITYFHRLTTQILSVLSDIVESSDDDEYEEDAYYDDDGDGDDNGYSYDEDNDSEASAANGANDNDGVVGRSARSSDEDGLVGARRSGLAGSSSSTALLLRRRNRTSSQRSRTLRSNTNISSNNSNSRRCPPPHTLRVNSDAVERMGLDVWSQADAAFVRDIALQYFCAGDSGNRHAVVHVESKGIEVCGLKVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X1</accession>
    <name>A0ABR3Z1X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF30">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="66341" checksum="20310DA4F21BE795" modified="2025-10-08" version="1">MPERTPNSMPKACDACRSRKLKCSNRGLTRALLLPICDNCVRAGIACVSSEKARRRRRSGKIVDALRSDSASSQKPANSIHLPHHHQHDDGDRLTSWPGINLQGLTTPGQTPLPGMTPGLTPGPSSSTSPPSDSSNRISPMSSLPFSISMPMPMQPPQHQNLTLEHTTQGFSFFMNTIYATWPVINYDDFTHRLQQGHDAWDLDFGILGHALDLLRETYDYLFVPTDSGTAKVMQRLAIVNQLRCTYDYAEAATADTVIVSFTMFVACIVMGKEQRALLYLSEASRLADFAYARAVRGHNKTEAMRTQRLKALLFITATATALLSSDPSWRMDVPSLLRVDDLTSWYGDADIEEADTPEGEEVPEQPVDPNKDIRDLDRFAVRQLQLMTRMYMMVGAQSGSSTSHLLMEDDVTKNISSVPLPRSPTVRVMVADLSITQLWFSCDRKTGATSGDNNNNNNNNNNSSTGMAVEKSVEEDLPENIGRKALAWARSLSQTELRMVGLGKMVDIVENMVQRSQLGQNQNSTSTAEVAMLADDLMAAIGIADYELRYAAAMAQCAALLRGQTAVATTTTTTVSASTITSRNENIDMHLFMEQTFDQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4K5</accession>
    <name>A0ABR3Z4K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734970" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="2">
        <location>
            <begin position="38"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="505" mass="51346" checksum="7871AED9D84C2BE8" modified="2025-10-08" version="1">MTFSKLLAAFTAAALLSTVSADSVCPTILNPSYDYPIVGEGWTAQLIASGLTSPRRLLFDSNGSLLVVEAGKGIARLTLTDHGGTCLVVADKTTIVSNTDLNHGLALSTTPSILLASTADVVYGYAYNAASGTVVGSPKTLVEGTGSSGESADLATRSILLSQKQTLTLVVARGIDSDSDDLAAIDESAGLGVVRVFDLSSLYTTTSTSSVIPDNPFEFSTASSSVSTILGWGIRHAAGLAEHPVTGGIFSTENSVANATYNGVDVHMTNPGDELNYHGTLNSSVSVSSPGGSNYGYPRCFAVANATSLTGSSLSIGDQFSMTQNSTLNDTTCAADYTPPTLTFGIHSSPQDLLFSSDGTTAYVALHGSDGIESGYAVGSIAFDNTTGLPTSASSSSSADFLTNILSNKNISKCPGNCFRPVGLAWDAAGRLYVSSDTTGEIYVLSRSSSSASTGTLVTTTASVASPTATATAAAGNAANSQFQHSTAVLGVAVASIAMALLIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5B4</accession>
    <name>A0ABR3Z5B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005208</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF6">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="104"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="47787" checksum="86DF7B2672F91D87" modified="2025-10-08" version="1">MGSAGPRSPHVLIIGAGMGGLFLAQFLRKQNITFSIFERDASLEARKPGWAIGLSMNDDFASFMPDDVPPLRDTNHLLPLELPSQFVMYPPGGATRIGVTDSAKTPCVRANRGLLRRNMLTGVDVQWGKKLERIEEDWKNNTVTAFFEDGTSALGDLLVGCDGTHSKVREHVLGVSNTETLQPLPMAMIGGETTLEYHEPDKDGKECLLARQLRLAFSSYMSIRPSGTFFCGVDRVSPNRDSARFYWFQFMRDATYGSEDHWLRTASQEERFKKVIEYIEANEFVSEHVDIIYHGGAKDITAEYQCFYDAVLPSLPTHGGRVFLIGDAAHPTTPFRGEGAIMAIKDARQLAGLLKEAVAAGEFDSDPSVFQEKLDTLQDEIARRGAEIVFKARRAITGRAGAADPKIKPTAWGYAVQPIPPYTGPLGLQVAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6G2</accession>
    <name>A0ABR3Z6G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">URM1</name>
        <name evidence="7" type="ORF">Sste5346_004944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="110" mass="11924" checksum="42EDBABB3648F280" modified="2025-10-08" version="1">MSASAGETIPIVVEFSGGLEILFADQKKLEVQLPAQDSKGQPATVGFLISHLCATAMTDGRKDLFVLEEDHLRPGILVLINDADWELEGEEAYEVQRGDNILFVSTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6T9</accession>
    <name>A0ABR3Z6T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="734"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="823" mass="86966" checksum="B25F93C687D8700E" modified="2025-10-08" version="1">MDTPTGSKVSLFHLQLFQFWYSAGFMPALGLDDDGVLSKAFVRLLRVLEEDSQLARAVEPEDVADASWSVKNTMLDCVEKFEALLDRQQQQQGSGAGPLAIAATTSTLSARLVEISIAVTDMLGQIKAAQTTQHQKDQAGLGLDEKTPYARSSSRWNVFSKTDSLASASSTSLSPPPPPPPPPPLPGMPTSLQGWPIRGPPPPPPPTWSQSQSAMTPFNPNPPPPPPPSYSSNNDKAVASAAALENTVVLRFMHDHYFQGSRASDYASAERLFEIVRQIAPEGSFSYTSMVEQGNLEAIVCAVSGWGLGQNALQVTPSRMAKVTYARIASVLVLSGTQLHRPAVVPLTAAPSVASSSAIDNGSDYRGSYSVASVSTNTCSSSAATVAASNKPPIFRVLAIAAAKAAAASSPDSPSSRINTFNGLPSPPPWNGYRPPPPPGPPGLRPGMSAVSRPPIRTAAGVPIHLRSNPGMPRPPMGRPSHPYMLPSTSRHGVPLPPGWRGSRNARLESVSKKKNKNKKKSSGLSIIDYSDSSSNTSDDSDSGSSDSDSDNDSDSESDSDLDAMLDWYKKVKDKKNKKSKKSKSKGKKKAVDDSDDSDWDAISERSATVCSASDSDSDASSSASASDSDSDSDNASDSEIDTVYDSDSHCKAKKSKAKAKAKANAKAAAKEKGRRTRKAGRMDSDVSSSSSESDADSNDSNSDADVKSDSDANTASDSDNDNDSDDSDDSDARSVSSSTASRTSVMDFLTGGTGKRKLSKADKKKMQAKEAKKEAKRKAEAKAKKAEANSSKGSKKSKSKTAGKGCRSAKVKRRSSFVVIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Y3</accession>
    <name>A0ABR3Z6Y3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039965">
        <property type="entry name" value="C3H7.08c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="125" mass="13633" checksum="4AFC46BCFE7E8DC2" modified="2025-10-08" version="1">MSFIARRAFSTSLRRLSSSEAQLKQETKRNPELYILGGIMVVGLAGAGYYFGRSPTASTSETAVSKAGMPWETGSSEGKYRYFPGGDHTADPKDAPSAVNVVVVPNVNLPKELHEKYNKWGKDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z770</accession>
    <name>A0ABR3Z770_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-rhamnose-1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DHG2</name>
        <name evidence="3" type="ORF">Sste5346_004555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="277" mass="28759" checksum="34A2A9C32FC2C02C" modified="2025-10-08" version="1">MSIPQLLVGKVAGVTGGLTGIGRAIALDYIRHGAKVGINHLGGAGDEPHLKSFLEEAKALVPAGDAVESHVVTFAGDISKPETGRQFVEHIVASFAKGSADGKGRLDVFVSNAGVCQFAEFLDLSPQLFEHTIATNLSGAFYAVQAAGRQMAHQTPQGGSIIGISSISALVGGGQQTHYTPTKAGVKSLMQSCAIALGKYGIRCNSLLPGTIRTQLNDVDLADTAKRTYVEGRTPLGRLGLPKDMAGPAVFLACEELSSFVTGAELLVDGGLYVNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7A7</accession>
    <name>A0ABR3Z7A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004847</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="24"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="261" mass="29151" checksum="AEE82BF1E93E44E2" modified="2025-10-08" version="1">MALQFVEINGARLAYRLEGPKDAPLLITLHGGRGFGTHDSDWAAYRPLSDKYRVISFDYRGHGQSSRTAPYTFKQIVDDIEALRKYFTSDKAVVLGGSFGGFLALQYAITYPDSVCHLILRGTAPSYHQEEDAIEVLATRLHKAPSFSINMLKDKVFGAFASDLEFQLVHLAMLPLYSEVFDADAALQSCLRGVYNAKAHNDLYSPEEKYFDYRADLHKITAPTLVVVGDKDWICPPKNSKLIAEKVPRAELYVVADANHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7D4</accession>
    <name>A0ABR3Z7D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004879</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050631">
        <property type="entry name" value="PheA/TfdB_FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476">
        <property type="entry name" value="3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476:SF4">
        <property type="entry name" value="BLR0106 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="409" mass="45707" checksum="3A4F691C1526DEBC" modified="2025-10-08" version="1">MAVAQEDFKIIVVGAGPAGLLLALLLSKRGIPVVLLDAASGPDQRPRATHYGPPAVYELRRAGVIDDVLADGFLPKKICWRKLDGTYLTGLDNSILGDDPDRVACLPLDQLGRILAKHLAKQPEAEVKWNHNVTGLGQDKGKAWLHVTTPEGETTVEGTYIIGCDGANSQIRRALHGDWNFPGRTWEEQIVATNVYYPGFEAHGYEDANFIIDREHWHMASKITKDGMWRVSYGEQGGLTHDELKERLAMKFERMLPGNPKPGEYKLMNFSPYKVHQRLAVKMREGRFLLAADAAHLCNPFGGLGLTGGIVDVGGLADCLYGIWAGKADADEILDVYDKVRREKYSTMVDPISSENLRRMISDPETVLEPGMDEFLTLCLKAEKNEEFAKKMMMGIYELQYDFTRHYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z801</accession>
    <name>A0ABR3Z801_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-tryptophan decarboxylase PsiD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022237">
        <property type="entry name" value="PsiD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF9">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G01730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12588">
        <property type="entry name" value="PSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-tryptophan decarboxylase PsiD-like" evidence="3">
        <location>
            <begin position="53"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="455" mass="51817" checksum="7AB5ED864054DB3D" modified="2025-10-08" version="1">MVWQHGDEHEIPDKFRRHHAGGWLPADHRVQHEWLRQTVEHIDNKSKRDALTPVLKEFQELIETNPRIYMYFTAMWDEVPHRKVYQRDPTGGRQIRDYVHMLDVLNHSFSRAPEWTNAAQSVGMVGVPLCAIFDYVMGTPSGHAAFLDPEVNRMLKKVLNAWGKYLLTPESAEVLGDHETGWFGKVGYKDLMEVANAPYKTDHKFEDMYICDPTAKHYGYKSWDDFFTRHVREEARPVAEPDNNAVINNACESRTYHVARKAQLRDRFWIKGQPYSVLDMLAHDPLAHQFENATVYQAFLSALSYHRWHAPISGTVKRAFVQDGTYFSEPLFEGEEGHSHHEIDPKGITVAQGYLTALATRAVIFFEADNKDIGLMAFIGVGMDEVSTCEIGVKEGQHVNKGDEIGMFHFGGSSHVLLFREGVQIEGFPHPGGNANVPVRSALAKVTGYVEKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Y4</accession>
    <name>A0ABR3Z8Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="867"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="880"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="902" mass="101498" checksum="8E96585798769AE7" modified="2025-10-08" version="1">MKITDLPSELINLVVAELARDDLKPLRLTHSIFINATERRLFTTVVISKTKRDLASLLGIAGTPRLAVIPTRLVWYELTEDHNHHLRMPKEKRSIRPSYSERVQYMLHDLIADSFWTEPFLADDDPEKYDPENAEWMATKEALYLSRREASQAATEKVIGEAVRQLVKIHTLVAQPMPIDRVLAVSDSGYHLDGEVLKNVMDGDAAYPPNGLFLFSRACLGDDLTNRIRSLYLSGPFTRPNVFARYYGASDDGLALFTNLTTIDLCMSWMLDVQISEGQELWTSDRTRCLPMAKCLQSASKLQHLTICFEAQPDQHTKRGLLDTVLFTDVGQEENKKDKGTEEGKGKEKEEETARREQDVHGGQQPLWPMLHSLHLVDALYEEKQIVDFVARHAATLRHLGLMDCLGHSTLIAAELAAIPRLQLSSFKVRSYMFYRGHPHTAREDYLVSEEALLAFVNKESSFNPVAKTKRKVFSTGPFIWDPRSWPAVAYFDLAASHTRHTGPKGDVPGLGLPGELGIDLGHQDEIMSAYSGAGDIRGENQPPQADHDGWYYATDSSEAEIEYGMDDMQDDDGAWPPRRNDPEVPLPYDAVDRAWITAWAKQTAHDEDINLDLVTAEPLGRDEPKWKAPFRQSLLLSDRAADIRHMERCRGENTEASPRWCWMRINSHQADSDDMSQEIYYWKTKVPGQGNPTTNWTFYKTFEDGTARHGFGADPLDFFSEWDSDSDKEYDRSDSDESDEDKDEGKAKKDTMHAEASVYSRAFKRFLANPFDRGDPLEADVDVIRLELVDDSEDADEDENEDNSGMDGQLRNVRNARRAEVAARKARNQLLDAARGHTVKGMLLVGVTADLLPAKVGMLVPKKVPPKPAERVVRAAQRSEASTTTETAATTATTATTENNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Y9</accession>
    <name>A0ABR3Z8Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nrm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004348</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039198">
        <property type="entry name" value="Srl3/Whi5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246:SF1">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="52"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="467"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="53"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="341"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="382"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="66568" checksum="DBEF30A9D1850129" modified="2025-10-08" version="1">MDRDAHVHDSRDARDVRDVLPRLSDRSDAPTSRASRALDVFANAQKLPSYSIHAQQQLLHQDQKQHQQQSPTHPSSQQASELPLPLSASSSASFQSSSRHYFQQKQPPSYTYNANGSDSQDTTSSADTSASTDTDQLFTPPISEGELSVGGGGSGSVNGSANTYNFEHDFSSQESQLHHLSRLAASRERMADVTLSDAFDGGALSRKRAADGSVKHTRNASSTSPIYTGGHSRNTSAVSVASTAGSRIGELSSELKTRLSYAMVKVNNGWQSHSIDQVENFASHGASPASSTSTIHGRHGSSLSPRIPGYSFHTRHQSQTSVSTSTTIAPTNRGLSMLDTSPWSSQQSSRSAQSTPPLPSPLTTSRSGSTAPTRALAPPASIQPSRPSTLGRRNSNPVFTPPTLPTAYSHQGSPHTPATFEGGHYRTPTADPILYTPHQNVREQDAIETLLFMSSPGNSSNMKQFLPITSSSQPLPAGHHDPQQHSSMMSPQRHALPGSAPRKSLPSGRPNAQFGRRGGHNRSPSEMDIDEPYGTPNSRSTKGTPKRRTNGAFDSSNRLSPRIKMPLSMPSGLGGTSKPRPVIGEDDIEKMLDRAAAASADDSSDSESEILIPARRTNHVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Z8</accession>
    <name>A0ABR3Z8Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-binding cassette long-chain fatty acid transporter pxa2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PXA2</name>
        <name evidence="13" type="ORF">Sste5346_004407</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF69">
        <property type="entry name" value="PEROXISOMAL LONG-CHAIN FATTY ACID IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="126"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="489"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="710"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="739" mass="82969" checksum="F06427B6F7549396" modified="2025-10-08" version="1">MAGQSKLAPLLGDQQKRTIRSLLSSLTRGYLNNRTRISRAVYVTLFLALVNRVRSAIAEQRAASEAEKKGHPAGLVDSSPDTPGAPPKRKKVELDRAFFRSLFRLLRIVIPGWRSKEARLLVSHSVFLVVRTLLSLQIAAMDGALVKSLVRGQGTQFLKRIVWWMLIAVPATFTNSMLAYHQAELALRYRTRLTHYIHERYLSNMTFYGLSALDDRIKNPDQLIAVDVAKFSNSLAELYSNLAKPILDMTIYTYSLSKSVGGEGVVFMSLLVQLSALVMRALTPPFGKYVADEARLEGEFRFEHSRLIDHSEEVALYAGHAAEKDTLDKGYFTLIKHVNYILRQRFYHGFMEDYVIKYLWGALGLLLCSMPVFVPIPGVGGAPLAAAADAANKSGMASVVRNMADRTESFVTNRRMLLSASDAFGRIMFSYREIMELAGYTSRVSTLLDVMEDVRAGHFEKNLVSSNDDTEDHAAVLKGRGTVVESDVIEFKDVPIISPNGDVLVPALSFCLRAGDHLLVVGPNGCGKSSLFRILGGLWPVYGGSVHRPPPTDIFYIPQRPYLPRGTLRAQIIYPDSLRNMRSKGVSDAELEKLLQLLGLEELLASQAESGGWDAVAEWREVLSVGWQQRVAMARLLYHRPRYAILDECTSSVTLEMEKTMYEQAKAMGVTLMTVSHRRSLWQYHNHILQFDGQGKYIFTRLDAERRLRLEDEKDDLDLLLRQVPDAEKRMAELEEAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9P5</accession>
    <name>A0ABR3Z9P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="650"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="689"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="799" mass="87864" checksum="578D0A01E3744E71" modified="2025-10-08" version="1">MASSSTPGPTAGGHSYSGPKPPRILACVLCQHRKIKCDRTFPCANCTKANVSCTPSTPAPARKRRRPNQDLQERLARCEELLKVYSSAKPDEGDSSGGGPLGVDPSQNIFGHESALKWKPPGKLIVEDDGGVRFVDSFMLGTIHEELRAMREIIDSEENEDTTPDTTTATPDDNSDLVLLGGMHGSSGQDGGPPVAATLEELQPSPAHIFRLWQIFLERVNPLTKIVHVPTLQPYLVDATSGSPNVPPSVKTLLFAIYTLSAVSMTPDECLNMLGYSRETALQRFSNGVRLSLIKTNFMKTYDLETLQALVIYLISLQGRYNRHAAWILNGIVLRIAQKMGLHRDGEVLGLSPFETEIRRRVWWQIIMVDAKYALMSGLSHSMLPRVWDTKEPKNVNDADLFPAATEPVQDREGPTEMVMVMVFNRLARFLVETPGVEPMILLSDHEAFRGPHGPSSQHIEMYRMLIANLATSLLEITDKFCDPSAGPLHEMALEVKAEVLQKLEHMLLPAKEREFSDEVKTPADNVFQVAVEATTHDNELKMKAKNNLFAWFSRLYFQDNMFMFIVGQLCIRTTGKLVEKAWVAVETTYDNYPDLYDVTQRVYYQIASYVLRAWRTRVGVLRARASLTGLPIHVPEFITKLRAIMPTQDETASTTSGAVGGGPMTTSSIKSEGSSSAASLSMMSGLGINSVPSTGPSGPPTVPDSSIQGAGGFANAMNGVAVSSSSDTPVPSIDELSLLGEDKPMQLPTTNDEVLDQLLSQPYMDPNNIDWDMWGSIMPTGSVVTPFDTFNSMPNTQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9V4</accession>
    <name>A0ABR3Z9V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="243"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="395" mass="42828" checksum="03F6A0896F519ED2" modified="2025-10-08" version="1">MDRSAPEYSQTGLPSPYPSHSGDTRSEASSLDHASAAYVTQQEVRPSNYSTAATPTSEYGVYPPSARSGSFPEHIQQRPYHPSPNHSGSGAGMAQTPSSPSLPLQAQQQQPPPPQDSPVEPYPYKSPVARSDNDVPIDPSIATQSPTTYAPHGQYSPYAPASGDMQQHGYPHSSSLYAQPRPDWAGYGGQPTPITPGHHVFPQAPNSAPPQPRPTQVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGQKRTPEEFKEIRKEWKARKKEEEAQRKAEDERQRQAAAAAAAAGGPAGGDPNGQPGDGQGASSYAGSRQLPPLGYQPNSYPAPPASGVAASSIPADYNNNYMHQNYPPQSPYGPPSNQQNMYGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX3</accession>
    <name>A0ABR3ZAX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004202</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF34">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="45"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="159"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="271"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="51210" checksum="41B99922CF7D383C" modified="2025-10-08" version="1">MNFELPSDVQDFLSRIDAFINKTILPLQHSDDNDRFFDYRRESSRTQWDNDGLPKKEWEALLRKTKRLADDAGFYRFAVPPEYGGSGSKSLNLHMCAVRYHLTSHPVYGGGVSLANDLQSEHSIVGNIPFIILIYHYGTQEQKNTLIPAAISGDCKATFGLTEIHHGSDATHMDTVARPITLPSGEPGYEIEGNKKWQSGMHHARFLTIFARTSGKAGNAKGITAFLVPRDTPGVEVQSYEWTLNMPTDHATVLLKKVQVPASAILGPLENGLAIAQSFTHENRIRQAAASCGAARYCIDRSVEYANRRLVFGKPLSKNQAIQWPLVELSTQAEMLRLLILRTAVEMDQVDAEAKAAGLPPWVAIEKQLGHKIGMCNYYAARLACEAADRAMQIHGGDGYSRHYPFEHIWRHFRRYRITEGSEEVQIRKVAAYLFGYKTTGEEAKKAAKKQHVEVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBW1</accession>
    <name>A0ABR3ZBW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="71" mass="7728" checksum="3EC46983DCBC4832" modified="2025-10-08" version="1">MAPRNDDATAAQHGTPTRDKSSQSDRTGSKTDTPPQTPGSAYSNETNGMANRIGRFRHLLTIIIISRHHNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCF1</accession>
    <name>A0ABR3ZCF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporulation-induced protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SIT4_2</name>
        <name evidence="4" type="ORF">Sste5346_003799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="493"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="567"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1109"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1205"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="609"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="703"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="992"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1116"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1129"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1152"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1163"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1233"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1283"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1298"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1374"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1404"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1440"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1452"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1464"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1505"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1531"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1567"/>
            <end position="1588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1626" mass="175071" checksum="02796CE791073C28" modified="2025-10-08" version="1">MFWKFGGYANISPIDAILDRLDFTLEELLDEGDLLGDVKAHNNKLLEYLRQKDVVLRLLEYVVAPKAEPVATPEKTEETEEKDDKEKVPESPEEAIERGRPRVFGRSRASSSATDGGLDEDDEAEKKRTRYAFVSCEILASDNWSICDTLLDPANRAELTKFWEFLKRPAPLDPLQASYFTKVNESLFDKKVEEMVNFLKSADGAVQDMLRHVDCPMVMDLLLKIITLDRPDAYQGIVEWLYTQDIMPTLLSFLSPENSWATQTSAGDFIKAIITVSANATQHEQTCIGPNELTRQLVSHPCIDELIGYMLKGGNALTVGVGIVIEVIRKNNSDYDPDVGTEANSIPSSRDPIYLGTLLRMFAQNVPNFMQLMNNAPAQKSRLNSTFGEKIEPLGFDRFKTCELMAELLHCSNMGLLNEVGSEELIAARDAQRKRLRAEGKLTGTRGEEVNPSNTDLLTMSMAHTSPTDEGRRLEVTNISAADEDGFEEVTHAAGLGDDDHPRELELPNRPAPTSSGATSSFLEKDKDDFVEEPLSSPRLKTHDDKVISSDDQHFDDPELLVAPLSPSKRKAVPVEGAASGGLVPVPKDDLAEGSDDFVTEATEPALGDEAKRMVPDLEKGDDSDSSIMFTPTISSLSESLDLGRSRRSPSPTGEPTTAPADETKETTSETPAEKTKASTETETGTPTTTPPTETPAIFAHEIPAEPKQVQDEKEDVKAEAARNGEAEPEFGEASIIVTQQPSEAGAAPESAPEAPVSDPVVGDFLKMQFVDHRVVPTILSFFFSYPWNNFLHNVVYDVVQQVFNGPMDRGFNPHLAISLFESADITTQIVNGQLVSEQSQAATRMRMGYMGHLTLIAEEVVKFTERHPAELLSETVVSKIMSPDWTNYIDGTLTETRERDNATLGGVRPEVAMGNHAAQAGLAAVGLSGLGSSLTSLGLSNSSQGTSNALAEAGLNGSLDLNSGSLDLQGSNDGHFSISAGISSGFHSSSDEEDDDADDNDEDINNEVSTNECDDDSNENEVHGDDTGFVYHRFGLVTRDGDLVSLCEDCIVEARMGMRPFGEICHHRFADELDDPNEDLSMEDIDDAINDFTALDADANTLVGSDHRSHRWFDDDQDQDQNQDQDQDQAREEKNANQEDGNVAKDQPREDETELILEAEAEASAPEPSTTAATATATDTTMVDCEPSGAQYRQGELFSEPGSFLLLFDGTADDTSGPSTAPDLPVQENEDKDNSNDEIHNDDNTDYNNLPEDDFHQRAQSATELFRAYTDPLNASNSLLPPAIPPPPPPPPPLNVPPSRARQLLAARLAMNKRNAESAAAQENGKEGEDGSGAVGGGNDDDGDISLGAASKSLTAMLDSGSGSGERLRNPFADDEDDEDDDVDADEDDDDDDDDDDDEDAGLNGGDVGRVGLGWNRGGWWRSMVTRTDKAGASKAGASGNGSGSAGGGFDNEKFGDGRDSSSDGANSSGDDNGPKNDDGLDDDEEFGDFAMPETTAQESSGSATETGKTAEGSGESGGTTLFKPLALHPGNPASGNPASSSSSTGAAASSSNTAGGSLWRLGFLGNNTTSGSTDAPADNTKQSTPTSKDDELEVLGEDGHRVVRVTEAAHRRSLEDPDEDEVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCM5</accession>
    <name>A0ABR3ZCM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="231" mass="25756" checksum="B36B070C08577639" modified="2025-10-08" version="1">MTFISEIVRFVLPAQRAADFARVRSQVASHGAILSQYYGPTMRDRTSLHVRPNEMCWVINWRTRPTNLAMQLDAVDGDNSATSLLFEFEDNQEENLAKALEAPLCQFATINLVPGSATDDPELQASMHKTYTDCFLADHGFTGGDWAYSSTTNRIDGVPLAESSSRAIINPNGRRLAVYFLGWTGHAAHDAYSATPLFAEEIDKLKSYFGPGTGAWYVNFEKHHDEEDAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD67</accession>
    <name>A0ABR3ZD67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MCA1_2</name>
        <name evidence="7" type="ORF">Sste5346_003846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="122"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="416" mass="45377" checksum="DCBAFC5B631B95B7" modified="2025-10-08" version="1">MSWNGGYPGQNHGPGHHGGGYGPPQGGYGGYGPPQGPPPPGYDQYGYPQQQYQQQQYPPQGYGQPPPQQHYQQGPPQGHYQQQQQHGGYDSRAAAPPPQQAQSFGHGAPSDYTFQYSNCTGKRKALLIGINYIGTDNALRGCINDVHNVSNFLMQRQNYRREDMVILTDDQQDPVLRPTRANILRAMSWLVQGAQPNDALFLHYSGHGGQTEDLDGDEDDGYDETIYPVDFKQAGMIVDDEIHNVVVRPLQAGVRLTAIFDSCHSGSVMDLPYIYSTKGVLKEPNLAEEAGKGLLGAVMAYAQGNLAGVATSIFDFARTAVKGDGAYKKTVQTKTSPADVVMWSGSKDDQTSADATIASQATGAMSWAFISAITQNPQQSYLELLNSIRDVLQSKYTQKPQLSCSHPLDVNLLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDP9</accession>
    <name>A0ABR3ZDP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003576</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="30"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="404" mass="43241" checksum="045EE12905A114B4" modified="2025-10-08" version="1">MSSAGLETRGPYINASIWTLQGLAGLFLGLRIYCKIFRHRGLWFDDYFLIAAWVLLAVSASATSSNVALGFGHHFVNFDPQNLEHYGIFSLLSGFFSILSAVCSKTSFAITLLRLTDGWTRRIIWAIIISMNILMPLSALFLFVSCNPPAKNWKPQLPGKCWPSNVSVIYGIVVGAYSSSCDLALALLPWRILMRFRMYRREKIGVALAMSMGVFACATGIAKCVMLPLLGSADFTYDGAPFVVWGFAECAVSIMAASIPALRALVNEIRGGPEFIQRMVPSLRLSPAAASKQPEEDSHATTVSVSPGLDLESGGNIEAPPPAYEVSGGGSAGLSFPSPSGSASPSASGSSLPKSDNDKSILAKSGLSNAEVAVDEVAEAGDPVGEHDVEMNTRRHSYNMQNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDR4</accession>
    <name>A0ABR3ZDR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003957</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055497">
        <property type="entry name" value="DUF7069"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031359">
        <property type="entry name" value="NACHT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23239">
        <property type="entry name" value="DUF7069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17100">
        <property type="entry name" value="NACHT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NWD NACHT-NTPase N-terminal" evidence="5">
        <location>
            <begin position="175"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="8">
        <location>
            <begin position="427"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7069" evidence="7">
        <location>
            <begin position="623"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="6">
        <location>
            <begin position="701"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="950"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="983"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1212"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1278" mass="142113" checksum="2536655C49C48E05" modified="2025-10-08" version="1">MFRRIKDRVKHKGHQKQPSSSTTKVGPAAQDASKTGILQLGQGDGKHNAAITVAPASTGQSENGHNDKTAALSQAGGEPSAQEGADKSDIAGPAVDLKPQTASPLSTDPKTNIADSSTFSPPSPSPPSPPPPYELSLWDRAYDALVAKDAKLVANYEKLLDAEVDSENLSGHEFDISDQITQAADVVLWAKDYISDAVSASPQASIVWAGVCLILPLLTAPHTANKANRDGFTYVTTRIQFYTSLEPLLQTPRPNQATADIKERLIDLYEKILYFQIRSILRFYQSNLRGYVEDLFQQNEWKKMQDEIKDLEAAINADLARMSELTSLQELTRLNKTCAGYLDKMQSLLSVTDQQLGVSRTHLGISKTQLTVVEEIRDIALQSQQDAKQQRLTRDEEKCLRLFRLTSSNKDITYEWYKNRVENRVEDTCQWFLQHVDFQRWLDQTSSPLLVSADPGCGKSVLAKYLVDHELPAKSASGTAICYFFFKDQDQNTARQALCAILHQLFTQNPALINCATDSFMREGPGLINSTASLWNIFRKAVHDPRAGPVTVVLDALDECAMSEFRDLMENLEELFPKENDEESQLKVIMTSRPYEQILLEFQPLLQKFPHVHIPGEEESETISQEVNSVIQYRVEQLAREKHLSDKLKTILAEKFLGMEHRTYLWVHLVFDYLKDALFKKTEKGIENAISKMPQTVNDAYESILARSRDRAEVRRILAIILAASAPLTLAEMNIAINIDGEENRPDSIDDLDLEDEDDFKTRLRSICGLFITINDRRIYLIHLTAREFLLRPDTSSSTSTAKDSLTTISPSLASDFSWHHSITTQEANRIFAKICILYLNCLDSEVVSSLKEDVRMDLLEYAAKNWADHFHEANVSTDDPLASIAFDICDSSMSKRNVWAPIFAEAQFGYSWDHKVLAGLLEMSYFGHLSSVILLLQRGADVNIKDKEYNNTPLSWAASGGHTAVIRHLLNSGATVNERNYRNETPLLLAARGGHVSAVEELLKAGADVFAKDVLDMTALHVATEHDQEAIIKMILQKGPSPCSVDMNDQTPFMIAIKKGVSSIIALYLQAGARIVPEEDYNRDKALCFAAKCGNKTLVKQSFDAGCNVNRARFKGRTALSLAVPFEELVQFLLSVGASVNSHDEDTGHTPLIQAALCNNEETIKLLIDARADVNAVDNEGKTALSHGVAQDGVVRLLLASGAKVDWKDNGGLTPLMWAAKDMKSHAIRLLIEAGADVSFMDPSGRNTLAVCAESRFHLQDQEEEIRRLLLEAGCSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZER8</accession>
    <name>A0ABR3ZER8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="567"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="72"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="262"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="466"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="781"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="928"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="932"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="945"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1080" mass="118420" checksum="81C9D2AF048DE365" modified="2025-10-08" version="1">MAVTKAIYSRLYIRLRVTVRMALAGIIHNRSLTIKDGIFEDSAAMTIVGSDTESAETVGEVIHDLWADLAEFCVGMYLLSRELGWVCICPLLVILYYHKSFVMATQMRVQATKDKLDAIKNIKMMGLVDVMEAKILEARKEEMKRYVTLSKLQIVFIVSAVALNMLSPAITLIAYVIQAEIRGTKAIDVNMVFTSIAIINIVTSPMVSLLSTVAEIAAMVADFDRMQTYLVSPDREDKREIINNRYTDADGDSTHTADRVAANIDNVTIRPASTADPVLKNINAVLKDGNLVVVSGAVGTGKTTLAKALLGDLPPDSGVIQTAYGSIAYCSQTAWLINGTVKDIICGPPNDDRTADEDWYRRVVHACNLEEDFDQMPNWDQTVIGSRGITLSGGQKQRVALARAVYARKSLIILDDVLSALDATTERHIVDNLIGPKGLFKEFGTTVLLITHAVYYFGTIGTARLILLLACLTMYASLVGFNPYWLRWLAEDDGQHAWFYTGIYLMIALGSFVFLSGAFMTIFLLIAPHSGYELHARLLRTVIHAPQSFFDTTDTGTTLNRFSSDMMMIDMQLPFSFFSIFQAVFRLLSQYILLSIVQPFIVAVLPFTFVVLYLVQKIYLPTSRQLRFLDLETRARVNSSFLETLEGVATIRAFGWQQPFIRDNAAKFAQSLQPEYLLSCIQRWLTLVLDLIVPVLAVGIIGLAIAFKGTTTGGQLGIALNVVLEANRYLFNLVEAWTRMETSLGAISRLRTFEKDVLPEDKHVESFQGTPTPAWPDRGAVSLSNLSASYKMPTLALNNVSVDIAPGTKVGVVGRTGSGKSSLLLSFLRIIELEGEGTVRIDGVDVRALPRNTVRGRIITVPQDSMLIMTDSVRQNLDIAGTQVTDEDMIRVLQRVHLWDVLQSRGASAEAAGREARVVDAAMGLASAGSTSGNGEGSSNGGSGSTTNKNSGDTTPTVSKASPTATLDTQMKLLPLSQGQKQLFSLARALLMRPSRGHVVLLDEATSNVDGETDKLMQTLVREEFSEHTVITVAHRLDTIMDSDVVLVLEAGKLVEAGPPSELEAKENGAFRTLIHGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEU8</accession>
    <name>A0ABR3ZEU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hmg-i/hmg-y, DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="56062" checksum="A8FC733CA0B17126" modified="2025-10-08" version="1">METPVAPPPVQEPAPSPVVVKPEPIRRGGFQYDGTFSTIDGVAFERPQHLLRLCYPSEPEKWKIKLGRGRPPKMEKITDMEASRTLSRKFMLAQFRFYGIPPPYQSSSDEVLAIFREQVTAGNFRKMTPDVETLRDEMVAEWDARRDPNAQRPRGRPKGSTRKPEDLLPATIVGAYVITSKEIQDQWSVNGTLTLDVAATATPGVYKGTFHFGVVLGVMILSADEKQLTSHVRRLDGGDDPDRRGGGDDLSAAGKRKQPPNGAGRHSDATQQQIMSGKKARTGPGAPPQHPQHPQHPQHLQHQQHPQHPQHQQQHPQHQQGSSGQGLAPIAGMQGMGGMPGMPVMPPPNMQGNLGGLGALVGGGLAGMHGSPGGPGGHPGHPGHPSNVGHPGSHPGSHPGVHQQQGTSVHNATAPETPSTPSTPMPQMSGRPPLKFYVRWRGRGLVDNNMQTGEHRGTLKFTNKHYTKFAGEMDLAFLGADEITGKRISDVPTLSGESWSDYMETVYDWTRNRWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG97</accession>
    <name>A0ABR3ZG97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">URA5</name>
        <name evidence="12" type="ORF">Sste5346_003003</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="81"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="25261" checksum="8B981C69EBCFFDA7" modified="2025-10-08" version="1">MSELAPYKAEFLRASINGGPLSFGSFTLKSGRQSPYFFNAGQFYRADLLASIATAFGQTIAEADKAGVFNTAENKDTSKPAFDVVFGPAYKGIPLATAAVGALAALDKERYGAIGYAFDRKEAKDHGEGGNFVGAPLEGKRVVIVDDVITAGTAKREAVAKIRTAGGIVVAIVVALDRMETLPDAPTKESALGALRREFGLPILAILTLDDIIAGMKAFATADDLARTEAYRAQYKAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGE5</accession>
    <name>A0ABR3ZGE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM5</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EFM5_2</name>
        <name evidence="5" type="synonym">EFM5</name>
        <name evidence="6" type="ORF">Sste5346_003052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03187">
        <property type="entry name" value="Methyltr_EFM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019369">
        <property type="entry name" value="Efm5/EEF1AKMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041370">
        <property type="entry name" value="Mlase_EEF1AKMT1/ZCCHC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200:SF0">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10237">
        <property type="entry name" value="N6-adenineMlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="254" mass="28468" checksum="49FC79F619A5DB57" modified="2025-10-08" version="1">MAPDSDDELTLSSSALDALKDFYKERDEREKKFAELQAAAEAAAKAKAHAQAEADAAAAALLPDLSMAAFTEDWNESQFWYSDETATLLARQLLDGTDSSSFIVVVSAPSVFIVLKNIVKTLPYEKQPRMLLLEHDKRFAVFGDEFIFYDFNEPTKLPASLRGTADRLICDPPFLSEDCQTKAALTMRWLGKPGPETRIVSCTGERMAELITTKLYKSQGVKVTTFLPQHANGLSNEFYCYANFECDDWKFQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGQ6</accession>
    <name>A0ABR3ZGQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Dihydroxyacetone kinase Dak1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">dak1</name>
        <name evidence="14" type="ORF">Sste5346_002769</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF14">
        <property type="entry name" value="DIHYDROXYACETONE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="13">
        <location>
            <begin position="11"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="12">
        <location>
            <begin position="403"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="357"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="603" mass="61916" checksum="54EC87BE0ED37268" modified="2025-10-08" version="1">MASLTKHFVNDPTALVHAGLRSVTYANPAVALDEDNKILYERTTTSNVSIVSGGGSGHEPSFGAMVGPGLLTGAVAGTIFASPSAEQIRAAITLLASRSAAAGHNAGVLVTVMNYTGDVLNFGMAVEKARAAGVPVSMVVVGDDVGVGRAKAGKVGRRGIAGTVLVHKISGALAARGFALEKVAGVAQLVADNLVSVGASLEHVHVPGRSVTDTADDALAADEVEIGMGIHNEPGSERAKGLKLPELVRTMLKQLLDTKDSDRAFASIGEGEDVVLLVNNLGAVSVLEMGGITAEVVEQLRDNYKLRPLRLLSGTYMTSLNGLGFSISLLKVPRDTGLGSDVPALLQLLDDPAEATGWSSPIPTATWDKAAKASPEEKAAAPAAAASESTSDSTPSNLKADPVAYHSALEHGLKAVIAAEPEITHYDTIVGDGDCGTGMKRGAEAILEHLSSPSAFTGDVVADVAAIVPVVERSMDGTSGALYAIFLNALVHALRQQSSAASGPTSPDWAAALRQSCDTLSRYTPARPGDRTLVDALYPFVDKLAESGSSVKDAAAVSRAGAEHTKGMKASLGRTVYVGGSGFEKVPDPGAWGLACFFEGLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHB9</accession>
    <name>A0ABR3ZHB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="172" mass="18696" checksum="F7D2769E5D6639A0" modified="2025-10-08" version="1">MMSLRAGSRLVSQRIAGGARVAARRSFAVTARVGQDASTAASAQTDLTPQSTNDAGAPTTTDLQQAPNRSGVWTRNQQPREKAMTGPRFEQTDFSLQPQPYSAMELIHQEPVRWTHDRIVACDGGGGAAGHPRVFINTDKPQICVCGYCGLPFANEHHRKHLESLPQTSYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHD8</accession>
    <name>A0ABR3ZHD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002981</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="10">
        <location>
            <begin position="269"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="663" mass="73227" checksum="410DF24B042BC2C5" modified="2025-10-08" version="1">MPFTTHMARMIIYLTTIGIIVACGLFTQLRSALPSFQRSLQSSKIWSKFQQYIFLPALLGRFSRHHEPSLGGVGYVPSRPLSLFIGVYLVLNIVLSCVSFSTFSPNAFWNSPQFNLCEFIGNRTGTLSLVNLSMAVLFAGRNNLLLGLTGWSQSTFLTLHRWAARVATVQAVVHSIVYTYAYFTPGYAGASAYAAEVAMPFYWWGIVATIAFCLAASFAILPLRTRWYEIFLVVHIALAILVLVGCWYHLVPHFGFIYGYQTWLYITFAFWAFDRVIRVGRVFYYSRMYIGAPPQQATVEAVPGSTNLVHVTVYPRTWNYGPGQHTFLYFPNLGWGKGWESHPFSVAAWNEKDSRQPAQQPLQEQPLQTASSPVLAQATASSSSDAGGVDDISQVHEKSVATSQVAASSQDEKEAPVEVHLPFHDSHQHHHNHHHRQSSTSPRPSIEFLIRTRGGMTAWLQEHAAAGRGRPVDSPLYTEGPYAGHRATLQPLNVADTVLCIVGGIGITHVLSILQEYVSAAKSRAVDGEHATFNGGRSKVMTRATRFILAWGAHETALLDHVQDRFLVPAAQVDGLEYQFWCSSSAGDDGKVQGYQEPVPGRVKVTSGRMDVASVVRSSVEVGRLTTVVVCGPGSMADEANRAVVQAVHDGFHVDSIEESFKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHG4</accession>
    <name>A0ABR3ZHG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase-activating protein gcs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GCS1</name>
        <name evidence="8" type="ORF">Sste5346_002414</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="202"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="393" mass="41240" checksum="CD34EFF030E247AC" modified="2025-10-08" version="1">MASKAMWEVDPETRSKLQTIQKESNNDICCDCGAPSPQWASPKFGIFICLVCAGVHRGLGVHISFVRSISMDAFKASEIERMRLGGNSTWRAFFENHSDTTMRGMTWDDATIAERYGGDVGEEYKERLSAKVEGREYIPSEKKPKPAPAAATSSASSRNTPLGGSRTASPLGGSASGGAGAATSGGKIKVDEKYFARLGAENAARPDHLPPSQGGKYTGFGSSPPPSQSGANGGALPGFEDLQRDPVAALTKGFGWFTSTVTKTAKTVNSDYIQPTAKQIAESDLAAQARVVSGNVARSAQQGARTAQEGFNRFVEGGAAGGSSSGGQYRAVNTGMDESKRAFWDDFSSIADTPATSAPARKTTVGTMAMGKGSSSSGPAEATSGKKDEWEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ1</accession>
    <name>A0ABR3ZHZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002572</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="6">
        <location>
            <begin position="393"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="747" mass="81026" checksum="1EDAE74C0CBB24CB" modified="2025-10-08" version="1">MRFLDLAADLAAVVGASRNVATKHVALRSRQIGASFVQNPQDPKKPAPEAAKTEDELTEGVPAAATADATASTSTASTSPIEPIEPIESSPAPTATPTPEPAQEAPKPDVQQPEMTDVPEDIALPTFIHRAQMRTTRLPGALKEIRRKAAEAAGPIGGPPKLHPLDPRAKLPPRPAAVTTSQTPVSAAVAESIEQGVFSKKKEDAPAEAPVVEEKKPDIVVEEVSESKAVPEPEATAEVTPDLVMPTEKLQQTSSVPSQEAEPVKTETVETHAPSTAQVPPIPEQLLRATPAAPPKRAFELKESKVPATRLSRIWNYGGLAAGMLGGALTESISRGFGGGSGDSGSVMLSAGNLERLVSRLSRMRGAALKLGQMMSFQDAKMLPAPLQEVLQRVQDGADYMPAWQRDRVLATNLGADWRDLFSEFEEKPIAAASIGQVHRATLRSNGAAVAVKIQFPGVADSINSDLDNLGILLTATRMLPKGLYLDKTIANARTELAWECDYLREAECAQRFQTLLEEAKETGVDGAFLVPQVFSEASGKQVLTMSFMDGVGVTKVAPDLTQEQRDWIGTQILRLCLLEITQFHFMQTDPNWTNFLYNANTSKLELLDFGASREYPAEFIDQYVRLLRAASISDLESVQSLSRDLGYLTGHESRAMLDAHTQSVMTLAEPFRADAPEIYDFQDQTITDRVRSFIPVMVRERLTPPPEETYSLHRKLSGAFLLCARLGSRVACRGMFEDSLKKMGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZID9</accession>
    <name>A0ABR3ZID9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="37642" checksum="DD98D6C9EAE7D83A" modified="2025-10-08" version="1">MPLDVPSFDDLPPVEGMPQGCAWGIFDKNGQKDVYGTLNLLTPDVVIAAAREVTEGVSVSLNWPISAIAKPAAGRCPLHHKVMAFTPEKHGFVGLDDEVQYNTQSSSQWDSLSHYAHQPTGLGYNGTSTALDVAEAVRDGKAGAQVLPTLEHWHNRGGLVGRGVLIDYVRYAKRHNIDYSPFSGHAITVEAIEEAAREQNNLEFKSGDILIVRCGFTEGMEKLDADRQAAVFKGRKYCGVEGTEESVKWFWNKHFSAAAGDSVSFEVAPPQVDDGKGGKRDGRIDEYVLHPYLLSLFGMPIGELWDLKALAEQCEKSNKWSFMLTSAPLNVPGTIGSPPNVLAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ22</accession>
    <name>A0ABR3ZJ22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="886"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="970"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="790"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="823"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="983"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1178" mass="127680" checksum="CA80A13E2584225A" modified="2025-10-08" version="1">MSGLVPVLRPPPLSPGNKGILLRRAVNISSQQTKLLEEETSWLGSDGKPNVNHKLVPDKVLEQLKKQAVQDKTQSTAPSQRPVTPPLEFDDPVPENPATPKATTPRKSQKELREGIREARALSQAVISPPPRSAGQAIPQLPKDTTSVRTQPNGEKEGGQETAVPASTVVEPQTSTTAPVAAAQVAAAPPVSAPPTAAEVLEVPAQVAAEPIPSIESDGVAAEVQNPDPVQTEEPVAEREPGPQAEAEAVQSNMEPERQPESEAIPEPELIRERSLAQETRSSPPTLQFSRPYSPDWSSVPPSEDIEEGNDEVGSDRDGDVNFNADIRTDEEESGQSADGERTEKDKDELPGLLPPTPHQQQQQTAPPAPSEPPQSVPSRQVYHGRSPELGSSSPAPIDVELPDMLIEGSQLRSHLLRRGTYSDSVGEQPSSSPTPKLPRSSLRRPVLLEQQEESQEQQERQERQGSSERQHPAHIVRPDFGLQEIKDDKDDDIVSEVPETISTNAEAAAKPQPRRRRTKPAVFPPKAPTQTRPPPPPPGVTISRDPRRQPSLTHPPVKAIKKNGIATSDMSTSPIVTPSFQRTETYTHAVAEHRIASVVATPAPVAHAPAPTPIPVAVAVAASSPPVRLPTYNNTPASQQHIHMPMPSNTASPNPNLLRTWMMPFELFTATYPDYRGDLEDFLRACYSLQHSSPSALPSFVFDDIVHTFLDYIEYVQTIASGSPQNLTQWYNLNATNLVHNQNVVTRDNVASILNAYPEEVKAIQTKTPNPNVQADASDAHTQGHVHGSSAKAAPSSSQAEQPSSHESLPPGRPFPFEMGHRPSPVGSSGPSNSILHDLSGYGNSNSTDSGRDSLRARLAQSQSIGLSQNLSQENISESIRHSHAFGPTQSSWESPHVNHHDNRQLPLPSSPVASAAVPAGMDKRAYMLRSLEPVTFTQMQLQPQPQTHMPFTQHLTNYAHEFSIEETPARPVSSARNRGHQQFQEITPQQQPSTTRNQKTPASAATNIRTTSAGTVSAKKSGPLNPTVPNGSSPQQAIVIEEQRDQDVSATFDMTWDEDDEDGDIDFETSFMSVQSAAEARRPPSKPITATTQSSGGGVSKERRRATVAASDIGMLKRITAAEDRDAVATKRVLPASMKRASTDGQPPRKKKKKAAKRLSFANFLEREVGPKPRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJT7</accession>
    <name>A0ABR3ZJT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002027</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="13"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="493" mass="54068" checksum="C36BB1344D6C6C5F" modified="2025-10-08" version="1">MGTLTGTFRASYLSALACVGSFLFAYDTGIIGGVLTLPSFVEDFRTGGNTNVSSNSTSLLQAGAFFACFFAWPFTARFGRRYTIMLASLIFCVGAAIQVAPTHSLAAFYVARVISGVGVGIATVIVPMYTVEMAPKEIRGKLGSLFQFFFTLGVMTSYWVDYGVSKHVAGTTSSQWQIPVGLQLVPGGILGLGMLLTKESVRWLAIQKREDEALQSLVWVRGEDSPAVREEFDEILNSIREEELLTEGYSIKELWLPINRYRVALIIAIQIGVQLTGNTSLAYYAPQVFTAIGAGANNLFFTGFFGVAKVVACALFVLFMIERFGRRGSLMFGAFAMGSFMLIVAIIVKTHPPSSTTTAAGGIQKTSIAAVVMIYLEAMAYNMSWGPVPWVYMAEIMPSRIREGAVAIGTATQWLFNFAFSQITPHAVKNLGWRTFLMFFIFNWSLAIFAYFFIKETKGRSLEEVDAIFKDRPMANRADAKDAEKPAISHAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE0</accession>
    <name>A0ABR3ZLE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057203">
        <property type="entry name" value="DUF7881"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25324">
        <property type="entry name" value="DUF7881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7881" evidence="3">
        <location>
            <begin position="36"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="147"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="37350" checksum="31CB61E191198FBC" modified="2025-10-08" version="1">MPFPNRLDGRIVHLWHAPQSGSNGELDFHVSNYLLEHIGGLRVVSGLTNHDLFEMVSIILRCIPLEDLTIHKRDQYHIDNIDNNNNKDLEAGDYYVTTRNNRGRVSAIQVFDRLPVGNAAYHHVERPYIARQQKETIVHVRKRDRGCVLTKTPNCGASVGDWTGFEVAHIFPLYHELVDPDRITRDLPDFMSRSSLTGHVAHSPQNAILMRSDVHRHFSQYQVAINMDSPGGPKIVAFTQATAWMSGTRINSAWLAYPDRPPNCFWQWHYKESVLANVRWVGAPVYTEEDVQEDVQQRNNKARKPFTVHSDDDLDYGTDTSVSSVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM49</accession>
    <name>A0ABR3ZM49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="7">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="321" mass="34168" checksum="8F9E458FC398F953" modified="2025-10-08" version="1">MADIDLQKVHDTLVSIAFEAGRMILAADPNNIPKGTKKNSVDLVTEADQAVERMVYARLRADYPTCEFVGEETYVAGETRVTDAPTFIVDPIDGTTNFVHGFPHACISLGFSVGRRPAVGIVYNPFLDILYTGIKGQGSYMERNASLSRVEGSGVTSQKLRLPLAGRGDVQEAPALRGLGTALVGIEWGSDRQGANFDLKVGVFQRLAAAKEGAAAPAIGKNAMVHSLRSLGSAALNFCAVAAGQLDCYWEGGCYAWDVCAGWCILSEAGGFVASGNPGDWEPALDSRLYLAVRGAPEGGKELVEEFWSVIGDAGTMKYVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN98</accession>
    <name>A0ABR3ZN98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08586">
        <property type="entry name" value="PI-PLCc_BcPLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="2">
        <location>
            <begin position="178"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="56443" checksum="D7F56712626E8CC9" modified="2025-10-08" version="1">MASLTIRNISVTPLELTQVERFEADAVEGTRGVSDLFWGLVRAPYDYISGCSANPAGGSSGSGLVPKEGAAPTTTDKIADVHVAPFSTTHTPVKAHDPGSEVLRLTFKATFDGGANHRTYTVDVPSATPRSIELRPVDGEADVAGAAAAAAFSAVYTASGAHLAIMSSAALSRWMATVDGAWPLSSLSLPGTHNSPAFHYALPSVRCQAVDVRTQLDNGVRFLDVRVSVNPPKQPHADPRLSLVHSVFPVGLLGSHLFSELYEAVCGFLDANPTETVLISIKREGTGKGTDADLAHQLVNHYTGGPADLTKEKPADHSAKQPGQPEPWRWYTESRIPSLDEARGKIVLIRRFHTPDEDTFKQLHGGSGWGLDGSSWPDNCEDGVCGSGPIRLQDFYDVLQTPSIDTKITYVRGLLAKSASETFSKIGGLHALGNNSAPLPPLPPLFINFLTGSNFFNARCWPENVAARVNPSVIEYLCVQHSEAADDKATAGDGSTGIVVTDWVGHRGDWDLLRCIVAWNARLQLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNK1</accession>
    <name>A0ABR3ZNK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2790">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="436" mass="44973" checksum="0A1CF6850A7638A4" modified="2025-10-08" version="1">MAWDSKAALASRRRTNSSASRTSASSILTLQQKNGTPVQPKSAHVADPFLQDFLQPGFDPATYWNTVLGGGGSISAGTGASRTRSPAPSSSGAAGRLAAAASSATATADRAAQAQATLSQLGAHTSRLTTVLIQLTDDILRSGRRLAYEVQLLRGETLGLGEVVEKHLALLDETDSGIAPAEEAKGVAANKEEGEEGTESGAAAAAAAATAGDPTASSSEPPSLAQLRMLAQVRSRLDAVIRTFGEAMEFIMPPSAISVTSSFLSVSGPDQESGGSAARRAGGGQDAATTTSMEDKGQNILRGLRDEITRLLEGANVNDGAEAAAARVEALRTLCRVWAGTAEEKARLKFIESLQRMVEDKQKELDCERERLERLQKEKLERESSQGNASGSSGGASSAGQGQLDGSAASGTGASRGYAAAGLGFISQLQKIRSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP37</accession>
    <name>A0ABR3ZP37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="84" mass="8965" checksum="06DABB4735BCF80F" modified="2025-10-08" version="1">MGVLLGYMYLLLSNGSRLSMSMRVSMILREEMPMAKMVMNVGMGMSLQPGLLLSLGLDMCLLTCLGLGLGLSLCNGGSSLEDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPE0</accession>
    <name>A0ABR3ZPE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="9">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 15" type="primary">PIM1</name>
        <name evidence="15" type="ORF">Sste5346_001013</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10 11">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="14">
        <location>
            <begin position="201"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="13">
        <location>
            <begin position="975"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="68"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="300"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="872"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="885"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="904"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="935"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="1067"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="1110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="653"/>
            <end position="660"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1191" mass="129202" checksum="58652264E7BAE3E8" modified="2025-10-08" version="1">MLRQHASRRLLASSAPRCARPAHIRLLSTTPSSRPRLAVAPTASSSAASCLSTRATALLLSPRMPSLNSASFSTSPIQLKKEPRGFFDATGNAEEDAKNKAKEEEEENENKDKADEAKSAEVEATKDTEAEPAKAESKSKSASSDQESPADGKPSSAASSAGSSSGSDSGSGDGGNGKKGRKSNADKALQKPVVPEVYPQVMAIPIAKRPLFPGFYKAITIKDPNVASAITEMIKRGQPYVGAFLFKDENADDDIIHKADDVHDVGVFAQITSAFPLHGEGATGLTAILYPHRRIRLSTLIPPGSGSSGVSEASVTDADKTPESTEVAEGSETPVPDPIPAKPTDEEAQREKKGDVVASFEESAVTAAPKSDSPSSKQQSSHPAQYEPTSFLRKFNVSLVNVENLTEEPFDAKSPVIRAVTNEIVNVFKEVAQMNSLFRDQISTFSMSQSAGHVTAEPAKLADFAAAVSAGEPAELQEVLSSLNVEERMQKALVVLKNELMNAQLQSKITREVESKITKRQREYWLMEQMKGIRRELGIESDGKDKLVEKFKEKADKLAMPEAVRKVFDDEINKLAHLEPAASEFNVTRNYLDWLTQIPWGQRSAENFGIHNAVTVLDEDHYGLKDVKDRILEFIAVGKLRGTVEGKILCFVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVAEIKGHRRTYVGALPGRVIQALKKCQTENPLILIDEIDKIGKGYQGDPSSALLELLDPEQNSSFLDHYMDVPVDLSKVLFVCTANMTDTIPRPLLDRMEVIRLSGYVADEKMAIAERYLAPAAKEMAGLRNADVTLSQDAIDELIKSYCRESGVRNLKKQIEKVYRKSALKIVQDLGDESLPAAATAQEALSKDKDEAESVTAADETAASEVSSEDDASSTTSTTSSASESTAATETSEDGTTSATSKTTTDKPRKPLDVPESVHVVIGRDNLKDYVGPPVFTSDRLYDTTPPGVTMGLAWTQMGGAAMYVETILQSALRPSSRPSLEITGNIKAVMKESSTIAYSFAKAMMVKEFPDNHFFDKAKLHVHIPEGAVQKDGPSAGITMATSLLSLALDHPIDPTVAMTGELTLTGKVLRIGGLREKTIAARRAGCKTVIFPEDNMSDWLELPENIKEGIEGRPVSWYSDVFGIIFKDIDREEAGKCKICEWKKLHDKDDSSKKDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQG4</accession>
    <name>A0ABR3ZQG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HotDog ACOT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03442">
        <property type="entry name" value="BFIT_BACH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="6">
        <location>
            <begin position="102"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="HotDog ACOT-type" evidence="6">
        <location>
            <begin position="308"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="53479" checksum="EF6DFE9EDE61D12E" modified="2025-10-08" version="1">MASPSTAAKRLLPALRTRTSRPSTQTIARPQLSQSSSSSSSLSRCRRCFTTSSPQRTDGVFRGLTDTRLPMPWIEAFRLQQEGQKVESSETKNNGERDLTPKKMTDSYHRVVLPLGRDPWLSDTYINSSGHIRLGTIFMDLDALSGIVVYKHTGPGVTTVTAGVDRIELAHPLTEICDLEYSGMVTYAAGGSSAEITCKVARARDEGEPSRPEDLLLTCTFTMVALDPMTRKPTPIPRLVCETPEQEELFQAGAAKALAQRAERKTSLLEVEPDDEESALIHRIWLRQLEYHDPNRPLRQPPNVVAMARTQLSTAAIMQPQYRNRHQTMIFGGYHLKQTFELAFCAAASFAHARPTFVSADPCTFRSPVPVGSVLYLTATVAYTDPAVVEEDGSEGDSKDSPPLTRVHVRVDSKVREMEHGTARVTGQFHYTFTVPKDVRVLPHTYEEYMRYIDARRRMRAGAKSRAASPQIIQGGVNLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQP4</accession>
    <name>A0ABR3ZQP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="4 11">4.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_001422</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2</text>
            <dbReference type="Rhea" id="RHEA:10792"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016301">
        <property type="entry name" value="Ade2_fungi/plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054350">
        <property type="entry name" value="PurT/PurK_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609:SF5">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609">
        <property type="entry name" value="PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22660">
        <property type="entry name" value="RS_preATP-grasp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001340">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="116"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="617" mass="65501" checksum="40B15258F16F51D8" modified="2025-10-08" version="1">MAKTPVIGLLGGGQLGQMLCEAAAPLNVPVAVLDADDAPAKQINRNKHHVAGSFKDAGKIRELAAHSDVLTVEIEHIDTEVLEAIATNGATPGMTPIQVHPSWKTLRLVQNKYEQKEYLASKGLPVAKQVAIETGTGMRASMEQAATAFGYPFMLKARKDSYDGRGNFKVGTAADLEAAEAEFGHVACYAEKWVPFVMELSVMVIRTEDEGAPGVTKQLLPYPVVETVHEDNICSYVYMPPRGLDGARLQQISAKAQQVACSVIDQLWGRGVFAVELFLTAEDEVVVNEIAPRPHNSGHLTIESIPYMSQFKAQLTAILDRPLPAKLEPHVASALMINVLGGATPDAHEKLIEAAQATFAPGLGVYVHMYGKEAKPSRKIGHITLTGTTLSIAELEEAATPLIRLAQKIREERLQAPTKALRPAAAAPVVAPVAAAASSSAVSPGVAANPLVLVTMGSDSDLPVLKAGIDILDQFGVPWKVDITSAHRTPAKMGQVATEAAARGIKVIIAAAGGAAHLPGMLAAYTPLPVIGVPVKATHLDGIDSLLSIVQMPRGVPTATVAINNSTNAALLAIRILGAFTPELLTKMEAYQRDMEQQVTDKAVRLRSIGVEAYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQZ4</accession>
    <name>A0ABR3ZQZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl hydrolase family 13 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001009</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF222">
        <property type="entry name" value="MALTASE MALT (AFU_ORTHOLOGUE AFUA_8G07070)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="3">
        <location>
            <begin position="19"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="615" mass="69987" checksum="A8425C45B0C5C17B" modified="2025-10-08" version="1">MAAPSPSSDAWWKEGTAYQIYPASFKDSNGDGLGDIAGILSKVDYLKELGIDIVWVSPMFESPQIDMGYDISNYEAVHAPYGTIEDMQALIDACHACGMRLILDLVINHTSAEHAWFKESRSSKDNPKRDWYIWKPPRDAENGTRLPPTNWRSYFSGSTWEWDEHTQEYYLHLFAKEMPDLNWENDEARQAIYDSAMRFWLDKGVDGFRIDCVNMYSKRVGFQDAPVVNPDVFEQPAWSEYANGPRMHEFLREMNNTVLNKYDTLTVGELPHTPDPRHVLKYVGAADKQLSMVFQFDIVDIGQGASDKYRFEEWKLPQLKATVAKWQQFIEGTDGWTTAFCENHDQGRSVSRFASDAPEHRVHSAKLLALMLASLTGTLFIYQGQEIGMINVPPEWSIDDEYKDIESVNFYHTAQKLADEKFAGDAEAIRREMDYVKRSIQILGRDNARTPMQWDASNKSAGFTDKPEGAWMRTHDLYPEINVAKQQDDPNSVLGFWKSMLHFRKAHADLFIYGNFRLYEPDNEKTFVFAKTTTKTTTGSGEGVSDTKQAAVIVLNFTGEDQTVDLPPADEFGALQFHVGNYTDTATAEDAGRQVKLRPWEGRLYLSSVATAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT49</accession>
    <name>A0ABR3ZT49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF63">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="49"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="399" mass="44764" checksum="A0985D93938A799F" modified="2025-10-08" version="1">MGALQGRIKNGKIFIINAQRRSDLSEQMLNSRTAAVHQLHRALVTSSEPVPDTYFSINFQDQPFGTTWGYSRAINPAFRSKDRDERNFLMPHFSFWAWKLPFVGSIGRTSAAIDRLEREMYPSFHDKISKAVWRGTAWFNSVHSPRLRQNLLAVAKGQSWADVEALDWVGGGQGQKNGQNATNAMAIEDFCRYRYVLHTEGVAYSGRFQFLQMCGSVTITPPIVWMQHTTHLVKPIFSSHMLTATTKSTKLVKPATEIKQQNKNEPPKKAAQKFAHAVKKVGGRSTSVARTENEKTSSGHKSWPVSYPADEANIVFVAPDWSDLKDTVAWLEAHPDVAARIAQNQRDLFAGGGYFSPAAEACYWRALVRGWATVAKVNPKEWAGHEEVSYESFTLNNGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUB9</accession>
    <name>A0ABR3ZUB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS8</name>
        <name evidence="5" type="ORF">Sste5346_000231</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="3">
        <location>
            <begin position="796"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="4">
        <location>
            <begin position="1409"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1437"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1498"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1551"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1673"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1721"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1857"/>
            <end position="1894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1270"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1510"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1551"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1678"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1725"/>
            <end position="1736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1894" mass="206233" checksum="76F87195BD8E1475" modified="2025-10-08" version="1">MSSSLTERDDDGGKENVVMGGSGSDLGGAADEDVPELPDPESSGADGDDDDDAKTIRGAEADDDVADVSISTDASVEVDGEDTATTPTEERPAISERLEPPSTPVRSGNGTAPRQRYRELLEENQQDSASEDGSALGLPRRPGSPGGESFVSVPDSSASNRNSMVSSFGGSSVFRSSGSLSRFGLRGSSPSFRPFDQRFQSRIASPSGSSSSGLLSPTGRPSSPGLLNFNLAHNRSSSRTSQYQDRSSASSVIGGSTESSTPPWEVVRWTKLTKLSSQSFSESAKRNFGSPTCMAISASIVIGTTKGVLLVFDYNQNLKLIIGMGTKAVEAGAITSVAISSDHTTVAGGHADGSIFTWDTSRSSRPFLHIPPMDAAQAQNPNRTASGHMPGFSVTHLGFLGSRRTALVSADDRGMAFAHLATRGTGALGRTVKTNRILGRYPGTKPPTSGKQIKPSTVLAFAPLPLGNVDRATDSMGLTAMLTPYLLVIVSTTPVANTQHKTPRPKEVAPHSAMSGCLAWFPAVRLNLPDPRSGEEISKAKLVYCWSNVLTVLDVDEIPSEDKEKQPTLHCKARSRWKCEEAIVAVQWLTRSVLAVLTISQRLIVLEDHSMRVTEAFDLLNRYIYHADLFSRQLQNVVETLDEEDTSMHGVVADAFYMSFKAYKGRLFLLGFNDMAIGALSNWADRLIALMEHGDYVGAIQLANSFYTGDADKRTIGLPEDTATRHKMVQERLMEIMAASLKYAFSQRQRNRETVDDSHLLELAQTCFTACESVGDTDFVFDQMYEWFEETGTEGIFLETLEPYILEQTITAVPPTVVKAMVSHYVSRGMEGRLEEIICHMNTATLDLDQITTLCKQHGLYDALVYVWNQAMRDFITPLIDLLSLLVPHMPNGEYEAPDNATGEQDMHDTNALKMFPYLSYVLTGRIYPTGEIMDEATQQQAKSEIFWFLFSGKSVVWPRGSSASKRFLTRPNQSQEPSFPYLRMILKFHAPSFLSALNEAFEDSFLNDSPEKQLVNGSTARDLPEEQVFGLTVDRQYILSILIEIMNPADFAPEDTIYLDMFIARNLPKYPQYLLIPESTLTKVLAGLCHYPGPDLEEDAQLSAEYLLSVYHPPDMSDLIPLFKTAGFYRILKRIYRSDKQYGKLLQTYFEDPNDRHGVFECIAECLHIQTTGDHAENPNSGAVKRRTQEVYNVIREHSFELVVLDPAEAARKLDEYAPELHEHVLESIKERHDLQHTYLKTVLEDADTDNTAVQESQLDGSRRRQKKQERDTPAASAETRRDLIEQYVRLMCEFDPSHVSDYVGIVQSANLRLDELLPTMEDTGVIDAAVVLMAQDGQVHEAMGRLVQHLHTLESAVQGLLTSGLAGNGNVLSNGEGKNGTVKFDEEEDARSDSDSGASNVTIVQRNAAEDLMRALQKYTHVGIWLCQRQTDTTIRRPSRQLSKSQQKKKKVSDGMGDNEEDDLSPDEKLWLDLIDTTVQITRNLSSHIHDIPEGERAADAAAAAAATTNGTTVSPSTDAGPVPKAEADKLVGLLRSLVQHTFTALLTTTSSGPLPSTPSPGSAPSRSNSRRGSAIAGAGNNLSFLRILKAFLTRAAVSSPSLADLRAVLASIFSAYAYEESILRLSNRLLERSLFVSVQRSVELRQRGWRAKGSTCEACGRRVWGPGVVQAHSGPGNTQNTQIPGQNGGGLSIYEAWEAKQAAETERRNEKKRAIMMASRGGLDRGKGKDNGDSHSTGKGKDRLAPSSPLLELPDRTVGGAGGPGRRTPSPRPGQLTPRGGGDGDLLLRPNKDDNGDANVAADGTLAVPGSEAGGLRSSPSAAALGPLVLFACRHIYHQGCLDALEAARAASEADGNSNGTGASGSNGNGMVHKRRQHGERDRDYVCPIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUM1</accession>
    <name>A0ABR3ZUM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="384" mass="40882" checksum="529F615AA1D80A8B" modified="2025-10-08" version="1">MAAKSYNQSLTSSSSSSSASYRHRHLPLAPLLSILTLNKDQPSAQRETELSRNAPPSSRGTFLGDAAPSSTLSPQTPQTPMGPAMPASHTVPSTSWLSLDDSCDDGNDHPLDFHIDCDSVCETTASTALETATIAATTLCGDERTITSSDGDASTVRGILVPAHPLTDFSNLLGMRSAAALARSIVTQDSNSTIRQTIGSRSSNITDDTSSSSFVLDPSRLSHATTVDHGLDDDDLYGWEAELEHRKSNSCSVAARPSIVDDLRRSVNKKNHSNSSSSSNSVISLSSERGEAVGRRRGEGQTRRRSFFQRVFSGKGPAHLGVKEAHCPNLPKSSPTTSVTTASGPSTIPRVAPQVSLPSEQFPSVPQLTTLLSDYTTMRDSNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZVF9</accession>
    <name>A0ABR3ZVF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SMP3</name>
        <name evidence="12" type="ORF">Sste5346_000120</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="505" mass="57632" checksum="667040D524DE334B" modified="2025-10-08" version="1">MSPSYLHPDENFQGPEVIAGEVFSYPVRLTWEFTSDHPIRSVFPLWPVYGLPMFLLRWLWIGNGGDGEIPPHVVFWVLRILMFIMNFVLLDWAIYELVPAKRHRQTAVLLVASSYVTWTYQTHTFSNSVETLVVAWSLVLIDRIVEGRQDRASVLAPMILGIVVVFGIFNRITFPAFLLIPGLRLIPYFINRPLSFAAMALSGLLTTILAIAFDTAFYTPHQISWGDLLFRPVITPLNNLLYNMSPANLAEHGLHPWYQHLLANIPLLIGPAAALLFLQPHLSLRLYSAVSGIFVLSIFQHQEARFLLPTIPLILSSVQLPRNPRLLNTWVAAWIAFNTLLGILMGVYHQGGVVPTQIFMSRQPDATQAIWWKTYSPPIWLLNGKNEVLQTRDVMGMPGEELMEQLTALATCDTPADRRNNEYLKEKNGTYLIAPLSATWLDQYLPNKGLEGLRFREVWRYRQHLNLDDLDWGDDGVWNTLSRVVGRRGIAAWRVTKSCPDKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFZ2</accession>
    <name>A0ABR3YFZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000151">
        <property type="protein sequence ID" value="KAL1887073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="351" mass="35498" checksum="8D76F2E72C14905A" modified="2025-10-08" version="1">MAYPPAPPLLLTRRLSSFLHSSLESLQHHKDQQPAGATLQTALLVTPSGKLLAYESPLPVRTLRTHCSVAASLWTIHASSSPSVAVALGQTAPVNQQPPPTSLSSPSLLPTRSTGDMSSPVEEDQEEEQYHDGSAPVSIAASFNGGAVFVVRRLRCGLLFACSTPSPNGSGSRPSMATDPAATLSVIQLAAPLSTSTPSAPSMTQSSLLPQTNLPILQPPPSGAGTASSTSASSSPTPINVPSKPTADGAGSLAPGTSVRTTATSETYETALSGSDAGGLGGDADHDANADAASTTTTGTTTTIGGSGKNGSVAATLAIARRQVDELARLLDEKLGSLSVPEENIGINGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHK9</accession>
    <name>A0ABR3YHK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enhancer of mRNA-decapping protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EDC3</name>
        <name evidence="8" type="ORF">Sste5346_010042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EDC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612:SF0">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="YjeF N-terminal" evidence="6">
        <location>
            <begin position="192"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="502" mass="54392" checksum="85C57840A42363CC" modified="2025-10-08" version="1">MKDVTDVQEMGDFDFEESLAKFDKRTLFDQMRKDDQIDDADRLVTHNRKPGTAGGKNYHHTENVLGTPLPSSTITSKTITKEPQSVSRDFWNSEADDTHTAVAPGVGASGGMGGGDRLSGRELGSRQGSRRGESKVSTTRRSQSRKASAGTVGQGPSRVNSIAQASSAFSASQHFYVLPSERRLETVSALQMLNVENIAHNELGLTEDMMAENAGRGIAEVALETLSDPANKIRLGQVDLHGNGQLAHSAPAPTIVILAGNNKSGTRAVAGGRHLRNKGINVLLCVVGIERGEREILDDLRQQIRLYRNFGGRVYNKSDLFEHLRKTVIPTLTIDTPRIAASGKVPAVTLIIDALLGLVLSFDELRTGDQATVYELMEWANRNEAFVLAVDVPTGIDPSSGYVSIIDGARLYVRPRYVVALGAPKRGLLEAMAAAEMGDPAAGDVAVADDQALDWRLFVADIGLGAAVWKKAGTKIRRGVDFDEKWVLEMKYRGLEMDDDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHS2</accession>
    <name>A0ABR3YHS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Plasma membrane localization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EFR3</name>
        <name evidence="3" type="ORF">Sste5346_009929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000106">
        <property type="protein sequence ID" value="KAL1887871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039786">
        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049150">
        <property type="entry name" value="EFR3_HEAT-like_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21072">
        <property type="entry name" value="EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="488"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="914"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="956"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1042"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="914"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="961"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="974"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="998"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1064"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1165"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1188"/>
            <end position="1199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1257" mass="134918" checksum="8D57923C4CDBF706" modified="2025-10-08" version="1">MHAIAQKCRPKHQVLVLKCYPRTTKGTIDVKPNSSELSYLLYYATSRRSKIQKVGSFLERKTASDVWRQRIGNVQVTLKILEALIEKNPKDLPLFAPNVLKILDVILRSNDITMVESSIPTFEAFCSNHDASTLLADQFYLAQFEAVVRHYASFASTRLSPGKSRPSKPVAMRWRSAGLEAIKAVAASDALSSIAGRQYDMMVPMILENLWTDNEEFLDVLLDRAETEEKDDNDRQLKRRNSVATVRTADTAGDTNPIALSGTAMDVDKLAEQDLGVLAILCLKQIFISSSRSLIHYATLALLDFVKDRIDQGEAVVRMNPGSREGGWSVKICGLLLRWAPVQERYIILITVMDALARTPLSDETLNHHITLTTMIGSLLRSEESLIGLSVMDVLLGFIQHIKKLVQMPGDPAAAAAVAASEGPLPGRPDPRSPTTLAAIESVTTVASQRKELLTRLQQCIGDLATHVYYADQIADMVSTILYRMKPPRSSSGTGSSTPPGEKAAEDTKTDNEGAGDSPQKNNSSHQPSVDSLFSLSVAKTAVLRSIKAILLVANPKTNLGGNQTLSRNRVPIQVWEGTHWLLRDPDGQVRKAYVDALITWLDREVSHSDQRARDDSTIGSSISATSVIGNRPSTKNGPAAGAGGAASNLARRAVSSASNRGENGVAGSSTAKQPSSSRRRRTFFLSLLHLAIYDNALQFVDYETDIVLLHVLLYKLVDKLGVNATRYGLPMIFQLQEAIQDVETPQAKVRVGSLVHGYFWTLTEKFRFETTMVGHAIRNEVTRRRSKHFWVEGVHVPPNSLLELVGTPGMIRPQPRMPLHEIETEALLPFDDRLSLVENICAGYQETAGSPPQSPAISPSRGAGSFNFGIAGSGATAGNENGTDFDEEVPASYKSQMLSDWSRDAVIQAVQQSAGSKSVSLSGSRTGTMATSSNNAAAGGRTRLMANTSSGLGREYLYANDNSNNGPSPSGSHQNLGGANNNDNLTPLVTKLRKSSIRSGVSPSPGGSLSSRGGARNGTGFVTSVDQLKMALSGAAVHANLGSRHGEARGQNDEGEDDDDDSSSMASYDISASEFSFNPPQGVNAAAAGAAGVDQQQSSQPDAEGSGSSPIKQVTSPSRKSSTTGEFLEAPNGNGSNYKSGDHNDESVPPVPPLPSPIIREQHQFQAQQQANAAAKAGTPTRPMTSPPAKSASTSAAANVQQATRRNVKSRGGESILSSVLGDDMDTPPLDLTSLLKGIDSRAGENGLGNLSRPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJC0</accession>
    <name>A0ABR3YJC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000106">
        <property type="protein sequence ID" value="KAL1887876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="152" mass="15317" checksum="A7E0B5992F870978" modified="2025-10-08" version="1">MPVPGRPLSWRGSDVGPASGHLYNNAATSTTVQLSVSMAGDGSDLTFVTADALALVSSYLSQNSSSGPILAAAIAVANNSATGSPEAFFVQRCANTNMTTTKTVQNTFGVAVTNGGNMTRVKQAVELWASGACLDASTFASLPLTGGKGLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKL6</accession>
    <name>A0ABR3YKL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pq loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009289</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF11">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41079" checksum="0C32999F4AD9289E" modified="2025-10-08" version="1">MDALLSSPDLSSRCDDLRAPGVMNLIVSIFILVGMLVSYLPQHWRIIARGTSEGISPYFVLLGVTSATAGFANILTLPQSRQDVACCHELDTLHCMAGLLGIAQLGVQWLCFAFILVLFLVFFRYDDASVPIPEEEIREDQPRWQTAVLVACTCLVHGLFVIVVTAVLAAVAPQALSGWANTLGLMAALLAAIQYLPQIYTTYRLKHVGSLSIPMMCMQTPGGLLFAASLFARLGWGGWSSWGIFLLTATMQGILLTMAIYYELQRAYPDEDVADNAGANGNGYGATNGNGNGNGGLAPPKTSSRPLYRRVLSYRSARLDDNTPSRYSAHPEHYGTTPDEISDIIDRQESDAAAETEPLLRPGGIGNPRRDYAAHPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKS3</accession>
    <name>A0ABR3YKS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="105" mass="12407" checksum="EC0713B6FCDE32A2" modified="2025-10-08" version="1">MNWANKARKRWVQDGWFSNQEFSSWEEKQAYQEPRKDQWPGVIYEIDLTTLPRAEQPAIFESVKLQALLNVECGERGDYLFAKHEFLVLHRIPFATIAKTHKLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN32</accession>
    <name>A0ABR3YN32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycoside hydrolase subgroup catalytic core</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="65750" checksum="6C881B83421FDCED" modified="2025-10-08" version="1">MVRQSIRVGAVEPQRSPEGPFLYVQVTPRYSLYLDSETQGEFVVRTTLSPYFGLELPAAPSDNDGIVGNRVLHFTISLDDKDDNDSDTTSTESAASKNVLVRGTATFNFSGVTIQDTIVLFNLTAASSKLGGGPLKTSFSSQNITLTGWVASPDGSSNVTYVAKSGSLFYLPDKTTGSITRLDNAYGGFMFRGERGGSLGNASDKAGFRPFFPYGYYSSYDGFLAGATDNTSAASTIDPYAAYGLNAMTPLTQYPQSEAAFSYMADHTGLGIQFDLREQYTNQTWVAAQVTAARDNAALFSYWSADEPDGHQDPFSAPIQTRDTIRSIDPYHPVAVVLNCQDYYFAQYAAGADVIMEDVYPIGINTTGITKWGIVCNTTLGDCGCDNCQGDDHSIRDVSDRLDDLARYETWSGPQQGSPWPKTKIHNPQSFHGEGYWARDPTPAESWAMSLVAVNHGAQGLIAWVYPVAATNTTNGTTNSVLPAAHGKLAQVLTRSPTVDFIVGNARPTRLPSPPGMPNLDMSCWRHVDQLLVSVVNTGYEDYAAAPGNNGTAPLSIPIPQSVWISPSRPYTHIAAIAWGSPNLIWSYAGNNLSTQRIPALATGLVVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNE2</accession>
    <name>A0ABR3YNE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF8">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="47372" checksum="761150F05CAE7124" modified="2025-10-08" version="1">MGSLHSTPDSAAAVTVQTSNTEEAPKVEEQPVEVQTETAVPVTTEGETQTEAQAPAPTQAAELSSEQPIEDAVVVEVADAQPAAETVVNTPATDLTPASSTSPVDVHSLSYDELPDKRRVWPGAPGSREEGLGRLCLLTPDVVASAAASCIRTGKRVALNWDLTKLDIANFNRAPTQHHIMSLLGGAGFDDVYIFNPQQSSQWDGLRHFSSPYPGSDQRLFYGGVTTSEITDRSNTRIGIHHWAQEGIVGRGVLLDYVEYAKTHLPDIKYKALSDHAVPLSVLQDIARVQGVTFQRGDILFVRIGLTQEWDTQMSPADKLAYAQSSNPQHAGVEGTEEMLRWIWDTGFSAVAGDAVSFEVYPPQKSYKREGGEDVPGLFMHEYLLPAWGLPVGELFDLEALSRMCAEHQRWTFFVSSSPLNMPGGVSSPPNCLAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNP5</accession>
    <name>A0ABR3YNP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF5">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046855632" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="32"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="337" mass="36696" checksum="37CD8B0110A5B5A2" modified="2025-10-08" version="1">MKTLSAALLALVAPAYAGLRFPCSTLIYQRLDPAGQPGAFPSAHVHHIVGGNAFNVTMTGDVASRASCTTCQMSEDFSNYWTAVLYFKSPDNGSYHRVPNIPVQPLLGGSNGAEGGLTVYYTQFDLSRDNLKQQPVTAFKPGFRMTVGSPGSKTRNHIGLSYQCMSGGSRGTITADMPTKPCSGGIFTTHHFPACWDGKNLDSPDHQSHMYNTVNSDGFTNAGACPSSHPVRVPQVTFETVWDTSKFNSLWKSGAPNPFVWSFEGNSYGTHADYMFGWKGDALQRAMDKSECFYDGCGSITKQQMSVANQCKIKDIVKEDTLGWLTELPGWSDSMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPE2</accession>
    <name>A0ABR3YPE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="12"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="217" mass="23006" checksum="3EEE8801340F0551" modified="2025-10-08" version="1">MAPASTLRIPNSAVFVCDIQEKFRKAIHEFDKVILTSRKVLRAAAILDVPVVVTTQNRARLGDTVPELSSLYSADSAAQSGADKKAKLIVDADKTVFSMWTPEVQAAFASAPTPFSSVVIIGIESHICVTQTALDLLAAGYKVYILADGVSSSNAEEVPIAMARLRAAGATVTTSEGWMYETMGDAGIPAFRQIVGLVKDTSADTKLALSTLLSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPS8</accession>
    <name>A0ABR3YPS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1479 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="51207" checksum="55E89C36B65292FD" modified="2025-10-08" version="1">MGSVAELTQEQLPCPLLEERFSVLKQSLIAPDNRDKVIESYHRLTAALKAEADRIAKLGPAAVPEIDFADVAANGGELPPGLEATVRQTGCLIIRNVVDEETASGWEDELRQYTKSHPKIGGFPVHDPQNFSLFWTRPQVAMRSHANVLKATNAVSKLWHVSDGDIPFDLTAQVAYADRFRIRHPSKDENYTLKAHQDSGAIERWEDPLYRACYKEIFEGRWEDYDAFNADFRSEAKTCLYSDKSCTAFRSFQGWISLSHTGTGEGTLRLLPEVKLSTAYCLLRPFFVLGEKFDDVTPLFPGATPGHIQFKPTPELHPHLFMDKMTVGIPPVKPGDYVFWHCDLVHEVDSLHPGERDSSVSFNPCVPLCKYNLESLVALREAFLSALPPKDFIKYDHGEHESQHDDHGARKENILTEEGLRAMGFLPFDVDEEGLSAGQKAIRQLANEKLGFATAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ44</accession>
    <name>A0ABR3YQ44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008268</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF164">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="57043" checksum="C2EA711872EE20D6" modified="2025-10-08" version="1">MALLSIPLLLSAVIIATLITYVRRLVSKDASVPGPRLNLLTSLPLKYHEFRGQRTAYVHALHQQYGSVVRLAPNEVAFASLPALKEIYMSNGSGYDKTEFYHLFRQYGTPTMFSTLDKQTHSRRRRILADRYANSNVVKEEALHGIRERATRFTQLATSAPGQVLDTYIALHSYAFDGVTHHLFHPHGSNALRDAADEAIMREVSFDNSLVRRLLEYYNRPLEKVADALGLLPPQRSIPRAKQIVLDAVDASLAAADDNRMGEGDLKIESAPAANFTLLARMQDPALKLTRMQMAAECMDHMAAGIETTGDVLCWLMWQLSLPECQAMQERLYHELKDSSPASYDSLPYLQAVLKEGLRMFPSIPMSLPRYVPAGGREVDGTWLPEGTIVSCQPYTMHRFDETVFPQPDTFNPDRWLGTTAEVDAEMNRRFFAFSNGGRGCLGRHLAMAEMKLLLRDVYSQFQTVLAETKDGKPPADMSMSDQIISSRPKDQSCLLKFIPREATKEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ92</accession>
    <name>A0ABR3YQ92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS30</name>
        <name evidence="6" type="ORF">Sste5346_008482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="64" mass="7000" checksum="0869CD75048F4C81" modified="2025-10-08" version="1">MGKVHGSLARAGKVKSQTPKVEPQESKKTPKGRAHKREQYTRRFVNVTTTPGGKRKMNANPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQM8</accession>
    <name>A0ABR3YQM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="173" mass="19164" checksum="5B8270D172C94244" modified="2025-10-08" version="1">MSDEELDRDWKPNGRRPQSTIARSFSLELMDIFRIENSVADLDEQVDKRKQQVTSQTTELEALEARIREMEAMLSKNKTPGASGTNASPTSPRNARPSINGVFPPVDNNNTQSQSATPRPLEHRQRTQEQQQTQQTDKYGSSRPGTARASQQAVPGALPPTPVGSEDGDGDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRH7</accession>
    <name>A0ABR3YRH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transcriptional regulator of nonfermentable carbon utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ERT1</name>
        <name evidence="14" type="ORF">Sste5346_008202</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERT1/acuK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF1">
        <property type="entry name" value="TRANSCRIPTION ACTIVATOR OF GLUCONEOGENESIS ERT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="12">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="13">
        <location>
            <begin position="544"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="410"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="619"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="716"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="411"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="625"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="725"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="813" mass="86715" checksum="45F5D13523EB180A" modified="2025-10-08" version="1">MESNEGEVSDGVSDNEYDEVNLQLLREVDNNDNDNEKKYNNDNNNDEDEDMDRSNNNDNDAKTVKTTASVDGSAAEPKKKYDPKDPLRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLADGCQDGVRKKAKYLHDAPAEALRPVLGPNFNAGATTNTQSRAANGHRHPSSAGSDVSASNVPTFFTQSSASSYPVFSTSQTPAGTLPENLTFPNPQSPVSPSFATTASEANNPLNRLSLSSASAAMANFSPALFDPSNPALFNFNLEGINFGSQYAAMEFGMLGHMSSGAADDPHDPSSLSQQGGRAGSGVGSFSSAADVFGNGGVNQTLYDGGPASSSAGGLMNDFMNLDNSSNNGFYTQGNLQHGLPHAYAIAAAPASLQSPSTDNNSPQATNYGFDGSPTTAVYGLSNLNNNNGGNGSASNNNGQGRPSISQPTQPTPQQSLQQQQKAKGAVTNKALPQSILGKRHRDPSSIYELVKEPYMYVNGFHRLIALLQRRFAAGKILRIAKALSSIRPSFISCTRTLNRQDLVFMEKCFQRTLFEYEEFMNQVSSPTIVLRRTGEVAAVNKEFTALTGWTKDVLLGKEPNLNVNTGAPGAASGSLGGTASAGGAGGLGGLGNEDGNNSGNGSANNTGRAGLTTPRLRTLNAEIVKASEGKPQPLFLAELMDDDNVIEFYEDFAHLAFGDSRGSVNRKCRLLKYRTRDMLVSSASGSVVDEPQAAGGPTSAATTTGTTTTSSGTLRPANSILSSRVARIDGEHGIAKIERDGKLECSYCWHIRRDTFDIPMMIVMNFLPCYYPNQEPHQLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSP4</accession>
    <name>A0ABR3YSP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="510" mass="54990" checksum="1FE23F2228C7FFAA" modified="2025-10-08" version="1">MTEKNIPSIQDHVPGQSNKPLSQPPHAIEFSEVLAELHVDPITGLGELEAQSRLAEYGPNELEMKKGVQPFKILMEQVLNAMTLILVLALAASFGIQAWIPGGILGAIIIFNIGIGFFQSLQAKRTIDSLRNLGAPTCREVRDSKTITIQTFEVVPGDVINIGMGDAIPADIRLIEAVNCSTVFTKDRGRGVVFATGMFTEIGSIAGALNGNAGNKAATGSRLSRLWHTAVAAVGEFLGLTVGTPLQKKLSGLFLWLFAFAIICVIIVLGVNKFSSRHDVIIYAVTTAVGTIPVSLLLVLTVTIAAGTKKMLERHVIVRNLQSLEALGGVTDICSDKTGTITQGRMVVRKAWLPSHGTYIIAECPFDSDVKKMSVICQHLASGDMHVLTKSPRRVCSHVMVHMLTGDYPHTARAIAAEVGILPTEDKLRMLARDTVQTIVMAAHEFDNMTDAQVNELSELPLVLARCAPSTKVRMIKALHRRGRYVAMTGDGVNDSPSLRYADIGITMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT31</accession>
    <name>A0ABR3YT31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF23">
        <property type="entry name" value="3-PHYTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047483448" description="3-phytase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="512" mass="55137" checksum="ACBC9FAE26E336C6" modified="2025-10-08" version="1">MALFASVLFLAGAANAQVGAMLSPAFDVNFPKTSAATNPLNWLGANGPYAPGPNVYGISSDVPDHCTVDQAFFVSRHGSRYPDLGAYNGWVDMQNRFSAKNGYNATGGLSFLPSWKTVLTNPGLQMSNLSPTGQKEAFDMAYALRTKYPQLYNEGDDLYVWANNYSRVLQTAKLFVHGFLGVNATKLGHVVSVTSAGSVNAIGNSLGPSDSCPNFVDSSGGTFFTNWSNVYIPPIQKRLQALISGNLTFTANDIAQMPYLCGFESQITGRVSPWCNVFTDEELQYYQYSNDLRYYYGVGPGTDLPATMMLPYLNTVAGLLQKGPGALNGTAADGSDFTPPRLMVSFLNDGQLNELITASGVHDSQAALSDTEMDPNRLYIGNRFTTMRGTIGFERLNCAVKPSIGNASDLLPVSQRACAGKTKVPSFETSTTNHTFIRVLMNDIVYPVPGCQNGPGYSCLLDDYVEFVGDKYNKSGNWAQNCGVTAAGAPTVVAGASFYTNLENDFLQVISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT42</accession>
    <name>A0ABR3YT42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_007892</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02878">
        <property type="entry name" value="GH18_zymocin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029226">
        <property type="entry name" value="Ecp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF1">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14856">
        <property type="entry name" value="Hce2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 13" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047250439" description="chitinase" evidence="15">
        <location>
            <begin position="28"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="17">
        <location>
            <begin position="327"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="17">
        <location>
            <begin position="391"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="16">
        <location>
            <begin position="452"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="18">
        <location>
            <begin position="532"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="515"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1891067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1522" mass="161034" checksum="98F10FA59A708D0D" modified="2025-10-08" version="1">MLPSWVTSAAAAGFMLLSSGLIGGADASHFGLRMPASPKYKSRDGNCPTSCAIVGSDPANWPVYKNLNQLSKCEETIFYHISLFDNVDDGTSHHRIYACASYGSLKAPGAASSTMRVQQALDNATFTVGHWDEITPSGVDLRDLSKQVRRFIKSGYQITPANSTSASATAGAQPQVLFAQTSGGTVGLYVGKAIQSLSSVSTALKSLEQSLTSTNDTTGTVAMELCGTHYDADHVIGFIATSNTSFAPIQQVLQSWSKATCIDYNSTQTFVSPVGFTTPLAVPATNATSSASNNTVAARGLHGHSHNHHSSSPAHARAFLTPRADCTTVQVVYGDTCGTLATKCGISAADFTKYNPSDTLCSTLAPGQHVCCSSGTLPSFAPKPNSDGSCYSYNVVANDNCATLSAAYDLTNDLIESFNNETWGWQGCGNVLLGAVICLSTGSPPMPAAVANAECGPQVVGTVLGPGGTYNLSGLNPCPLNACCDIWGECGVTAEFCVDTSLGPPGTAKNGTNGCISNCGTDVVSGAAPATPISLAYYEGYGMDRPCLYQDISQLSTSFTHVHFAFATLDPSTYAVSVGSAASTYEFDSFTRLGSSFHRVLTVGGWTFSTDPSTYSIFRNGVTAANRVAMATAIANFVTDNDLDGIDIDWEYPGAPDIPGIPAASTDDGANYLAFLVVLKNLLPGKTVSIAAPSSYWYLKGFPIKEIGEVVDYIVYMTYDLHGQWDSGNGYSQDGCATGNCLRSHVNLTETMSSLSMITKAGVPSAKVVVGVTSYGRSFGMTDGSCYTPECTFGGGAAGSTATPGPCTGTAGYLADAEITDIIDGTNSTSNEKRRRRRDGTALSSRVNQYYYDKDSDSQILVFDDNQWVSFMTDDILASRTSLYKGLSLGGTTNWASDLQTFNDAPGNMPNWDEFLLAVKSGINPLSELAVDPSQISGNWTKLTCTDPAVVNVLTMSSEERWDGMDCPDAWADVISVWNNVDINTGVYLSASISASINGPENSNCGSLAATSNCDRILLCKDVEGTTNSGPAAYEIWNSLVYVHEIYETFHDTIVQAAALSLDPSLDEFENTFAPVTPPDTEWLDILLAFVNLAGTVVVSGFFNSILKALPFFRAHGVQYDNYKDAAKALVSFGVSVTSTYVSGSQSDWTAASQTSFSNYLGQVVNIWANSTESQLGQIFSGQPDTLPILSGLIDKGQMIEGADGSTSAAGTTPSVGISSATTTSVQDSIMLAFYAFAIPSAWRASGTGAFILDTGADCSDLNVAADYVDSSIQKQAMGCIDNHLYFLVYADGPSSDTCPAEGSCTDNSFSLPPGADKLDGSAWGKVTVNDIINGSVRTYTANGNKNGGAAADPSDTSTMGDLYDQDITTPGYIRLPVCSGQTAFWNWEEYSDRTLDNWPCYVPPPKNDCESSSFIDETSDASPSVDDCMHIVDNIIGTDGEWEIQTIGKAQHQLVQYGSCKFGIQATDLHGNIYFHIAAQDIVDIIQDSIKQFGGSGKIGAKGYMDCKGNINSQDVLWGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT64</accession>
    <name>A0ABR3YT64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_007572</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="416"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="779"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="806"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="840"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="880"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="908"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="948"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="98"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="260"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113595" checksum="5AB6186C0C2E70C5" modified="2025-10-08" version="1">MGKFLHRRKRSPTGEKDIEAHGSSRGFPSDGAAPPLLDPAVNLGEYPALDRYISLYQGDATQGAGSDDGNAKGRRKTKRWWQFWKSSGEEIPVRPAGAGADLHPEWTETDIRTGISEAEAEERRRRTGWNELASEKLNPFYQFVSYFMGPILYVMEVAALLAVGLGDWIDFGVILGILFLNAFVGFYQEKQAADVVASLKGDIAMRCTVVRGGVEHNILARELVPGDIVIIQEGDTVPGDARIICDYSRPEDFEIYKQLNEEDTFGNDDEESQPDAPERDEQGSTHGNDVHAPVSGGHGRMANYRSHSIVAVDQSAITGESLAVDKYMGDTVYYTTGCKRGKAYAVVLTTAKNSFVGRTADLVQGAKDQGHFKAVMNSIGTALLVLVMFWILVAWIGGFYHHLKIAEPGSQNLLHYALVLFIIGVPVGLPVVTTTTLAVGAAYLAKQKAIVQKLTAIESLAPIKGVDILCSDKTGTLTANKLSIREPFVSEGQDVNWMMAVAALASSHNLKSLDPIDKVTILTLKRYPKAREILQQGWVTDKFSPFDPVSKRITAEVHLGSEHYVCAKGAPRAILKLTDSSKELSDMYRDKATEFARRGFRSLGVAVKKNDENWTLLGLLSMFDPPREDTAQTIVEAGQLGVPVKMLTGDAIAIAKETCKMLSLGTRVYNSERLIHGGLGGSMQHDLVERADGFAEVFPEHKYTVVEMLQQRGHLTAMTGDGVNDAPSLKKADCGIAVEGASEAAQAAADIVFLAPGLSTIVLAIKTARQIFQRMKAYVQYRIALCLHLEIYLTTSMIIINETVTVDLVVFLALFADLATIAVAYDNAHWEPRPVEWQLPKIWVISVVLGALLAAGTWIMRGTMYLPSGGIDQNFGSVQEILFLQIALTENWLIFITRGGKTWPSFQLVGAILAVDAIATIFCLFGWLSGSPEVDIPLDVWHQREDGWSDVVTVVVIWCYSFGVTVFIAIVYFVLNHWPWLDDLGRKNRSHKDTAIENVLGHLQKLAVEHDKDAVGKDRYILVQKAIDEEEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTX9</accession>
    <name>A0ABR3YTX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="F1F0 ATP synthase subunit B, membrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="115" mass="12807" checksum="9D799D0CF4FEFBC7" modified="2025-10-08" version="1">MSAQNSTGIQTLLDAEQKAAQIVQKAREFRTKRVREARDEARKEIDEYKAQKEAEFKKFESEHTQGNKAAEEEANREADAKIVEIKAAGKKSQDKVVKDLLAAVLNANPVPPSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUE5</accession>
    <name>A0ABR3YUE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G2/mitotic-specific cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CLB2</name>
        <name evidence="8" type="ORF">Sste5346_007566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20568">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="273"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="366"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="370"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="460" mass="51292" checksum="526B942666030394" modified="2025-10-08" version="1">MKGRPARQRLVTNENDENSVAAARMTRAKAASLQVDELTVPAKPLQAKKPVQSSTTQPSGLRKRAALGDVSNVTKIEVAEAKKAAGKVGLVSKAAQPTGIQKSTSRSTGRTALSTKEASKKTIEVKKSGHGTIGTVQKRKVAAASAPVATIKEDLTVEEEEPVRKKVHTVASRLEEASTSSGNNNIKKDAAREQERLLPLDDSIEEFVPTEFIYPEGVKDLDSEDLDDPQMVAEYAADIFEYLRDLECSSLPNPRYMNHQDELDWKTRGVLVDWLVEVHTRFHLLPETLFLAVNIVDRFLSAKVVQLDRLQLVGVTAMFIAAKYEEVLSPSVGSFRHVADDGFTEAEILSAERFMLGTLNYDLSYPNPMNFLRRVSKADNYDIQTRTVAKYLTEISLLDHRFMSYRPSHVAAAAMFLARLILDRGEWVCSSLDFLRRIHRAPLCIAIWGPQLFIMRLPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV03</accession>
    <name>A0ABR3YV03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PUP1</name>
        <name evidence="12" type="ORF">Sste5346_007529</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="11">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="276" mass="29936" checksum="AD0C6B5E6FA4F385" modified="2025-10-08" version="1">MPGFDFSNYNRNAALHARGVPLPKATSTGTTIVGCIFDGGVVIAADTRATSGPIVADKNCEKLHYIAPQIWCAGAGTAADTEFTTAIISSQLELHSLSTGRKPRVVTCMTMLKQHLFRYQGHIGAYLVVAGVDPTGVHLFTVHAHGSTDKLPYVTMGSGSLAAMSVFETKWKPQALTRDEAVELCSEAIKAGIFNDLGSGSNVDVAVITKDKTTLLRNYIRPNERVPKLRNYVFPRGTTAVLNEKITIRKEDMGNFVTVHDLPEQSEEIESMEVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVI7</accession>
    <name>A0ABR3YVI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="54818" checksum="38CEB0244437D470" modified="2025-10-08" version="1">MPSTREAMRSSGAGPSATTPPKPSSLRRGAATKSSRLPRPVPGTSSPPSSPPSRGNATRPTAQDPPGTQQELMRADEAEEDILHGYLRTRRHNGEETHSFRPNNERFSEFVVAATNNRDLEQSLAEKEEQLRSSEAAAQRAVEDAKRAAGELLRSREREWEEREREWEEREREWGEREREWEEQEREWEEQERERQVMWDTEIQQLKVENEKKTDALKNKTDALQNKTEENQRIQSELDKAIRNRGALQGQLDEANRKLEDSDASRATLQEALDSAEQALVAEEQRHKKTQQLVRTEQMRAAGLEGELGTAQRKLTDAKRVQDQTQEALNQTQKTLNTKDESLRTALDRVAALHHQLNDAQATQRELDLATAEANIQVQQQLTEAKDTLAQTLESLGNAQTGTAAAEELLAITLEKMEQELKAAEARENRLIHQLTRLKGKLAKLRARQPSQRRHRRGQEPDRPELVSVRDPQERIGLARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW15</accession>
    <name>A0ABR3YW15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CWC21</name>
        <name evidence="9" type="ORF">Sste5346_007140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="356" mass="40187" checksum="29313F14F62F2E9D" modified="2025-10-08" version="1">MSDNVGLSTPRGSGTSGYVQRNRAFIRPRDNAYGGGPHGNTNPRDLLASQQASRLRQPDQGILEHDRKRAIEVKVFALRDELEEEGKLDEDAIDERCDELRKKLTEEAQRSGNNNSNNGGPADGRQRFKAHQVHEQARAKIVESERLRRALRINKDYQEGGHWRRQEEKQQQQAQKRKVEEESAHGGAASSSNDKRRRRYSGSGSDDGYDSREEGEVGRSGRRAASPPLKSVEDDRNDRRRPKDKDSSRDKKPASRRRDDYSDLSEGEVSDDSRRSRGSRGKGPARGRAAPRDSRSRSPRSASRSLSRSPSRSPSRSPSRSVSRSRSRSRGKSYDSRSPSRSRSPARRRSRSDSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW69</accession>
    <name>A0ABR3YW69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase</fullName>
            <ecNumber evidence="6">1.1.1.101</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AYR1_2</name>
        <name evidence="6" type="ORF">Sste5346_006915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.101" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000140">
        <property type="term" value="F:acylglycerone-phosphate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="282" mass="30457" checksum="4142E272C4CD57BD" modified="2025-10-08" version="1">MAVQRSVLITGCSLGGIGDALAREFHNRGLQVFATARNMAKMTELEALGITTLEMDVTSPESIKTAVAQVATASGGKLDILINNAGLNHVMPFADCDLADIKRVLDTNIFGVFAVTQALLPQLIAARGVVATVSSINTVLNPPYQIAYNASKAAVNSLGHTLRIELAPLGVRVVTIVTGAVATHLFDNTDERLHLPEGSIYTPLKERIEKKDFLDGITWTPARDYAREVASDLLRTSPKPVLWRAAMSTSTWFLNVFGWTGMLDSPMSKRVGLDKLKSLVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX16</accession>
    <name>A0ABR3YX16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serologically defined colon cancer antigen 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="6">
        <location>
            <begin position="613"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="7">
        <location>
            <begin position="989"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="504"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="758"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1095"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="325"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="505"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="775"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="797"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="833"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="872"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="888"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1099"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1150" mass="124219" checksum="B130376A770147D1" modified="2025-10-08" version="1">MKQRFSSLDVRAISHELNQALTGTRISNVYDLVPPSAASSSSSSNKTILLRFSRNQDKHQLVVDSGFRCHLTAYDARASANAAVGGNSGGGAANAPSAFVSRLRTFLNGRLVSGVSQVGTDRIIELRFHDGQLRLYLEFFSAGNVVLTDANSKVLALQRTVAAFRSASLDVTLSVGSPYAIGARTNVTEVPELSMDKLREVLAKAVAADAPKTAPAGGEGAPVVVVPAKKKKKTKGLSRILALSFTDLSQVLIDHNLLLSGFDTTTAAQPEDILADEARLQALLKVLQAVRTETEGLTKAGANCRGYIIATKKEVPEGEAKAAEEAQAQAQTQAQAEAGPTEPASESTTPAPSKRTDLDYVDFHPFSPRQFELDPKYVVLPFDTFNQAADEFYSHLQGLKADRQVHQQESAASKKLEATRRDQAQRIESLQETQQLNARKAAAIQANQDWVQLAIDAVNEQLQLGMDWGDLEVMIENSASSNPVAALIKLPMKLAEGTITLRLDEEPEEGWEEEYEDGAYDQDQDGTGGEDQDADEGRKMIDIDVKLSLSAWSNAREYYDQKRVAAVKEQKTKEVTSMALRNAEKKVAEELKRVQKTGKPAPQLIRRQLWFEKFLWFISSDGHLILAARESQQCEMLYRQHLRRGDVYVHADLKGSPGMIIIKNRPDTDVDAPIPPATLAQAGTLAVCASEAWDTKAGMGAYWVHSNQVFKSTVNGDILPPGSFDIRSEKNHMPPPQRVLGFGLYFKISDASRVNHGKHQVVVPQNNADDSRPVEDDEDEEEEEVAEAETKGVEEKPAEEEEKEEEEPTPETPAESAEPTEEASEETTKDTEDNGEEAAEKEDDEDIESAAPVAGWLGKAKSHLRASSPTPSRGSSVNTSSGGSGSKRGQKGKAKKLAKYKDQDDEDRARAEKLIGIAAGREKQEAKLRAKAQREAEIAAYEERRRIQKEKQMQKMRDYEAVRQAKLQAGAGDDNVGAGDDGDDADAGNLDLINSLVARPAPGDEILEVVPVCGPWMALSKLKYKVKLQPGPTKKGRAMRDVLERWRRAGEAGKTNSNIIDEESRDPERMWPREVELISGIKMEEASNSVPVGKLTLMQGGGFGGSGGGGGGGGKGGGKGGAKGGSGKGKGVGKSGAGGGKGGKGGGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXM2</accession>
    <name>A0ABR3YXM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ethionine resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ERC1_1</name>
        <name evidence="8" type="ORF">Sste5346_006568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="496" mass="52152" checksum="279E63E17B3F3C90" modified="2025-10-08" version="1">MSDERTALLAGHDGHTGPITETGTKTDPREWLAEMALLFKASVPVMFAYMLQNSLQTVSVLVVGQLSPEALATAAFSYMFAMATGWLVALGGTTAIDTLASSCFTGSADKDKGSLGVLLQRGFLVLTALYAAVALFWCFGSEPLFRALGQDPVISFQSARFLRILAPGGLGYVYFECLKKFLQAQGLYSVGTCVLLITAPLNAVLQYVFVYSLGLGLDGAPIATGISYWLSCGLLTAYIASAEHHGRAGWSGWAVRRAASTGMGAFAKLALLGVVHVGSEWWAFEIVALAAGRLGTVPLAAQSVIMTMDQVINTVPFGLGVAASVRVGNLLGARDAAGARRSAHSAAVLSVILGTLLLILLMASRHVLGRVFSDDADVAAIVAAVMPYVALFQIADGLNGSCGGALRGMGRQWVGALVNLVSYYGAALPAGILLAFHGWGLTGLWCGQCVALFLVGLLEWGIVALSNWPAEVRRAFDRLEAGGVATVRSEFDEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXV1</accession>
    <name>A0ABR3YXV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039634">
        <property type="entry name" value="Bul1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="60928" checksum="5E325CD0849F2059" modified="2025-10-08" version="1">MSRTRLFLNLHGESMSGVSTNGSSSSSNFSGSGPHRSLAFPKSKMEIQLDRHFQAKVYTSGDSITGSVTIVPQRNIPFDEFEIVLLGTTYTRVEHISSPVESSHVFLKLFMPIAEDAYPVPRVLEAFQTYTLPIHFVVPHHLTLSACSHKVASPHVHAHHMRLPPTLGRGSGSGAVAAWERDDMAPEMSRVEYSIKARVYRETLKEDGSGKSTRVKVVEATQPIRILPASQLDPPLAVSKKDRAYKLQSSKTLRKGLFARSKLGRVTAVTGDDASGAPQPTPIVLHPDGIGSTPTNAYVQVYFDPARPDVPPPRVTSVSAKLTAHTHYSTSAITTFPNLGDWARTDNIAMERRGSYSTSVSLLNNTLKSFQWEAKVDNGRRDSGYCSSDSGGAEEMTTGSPRRLSPASPGNSKDMGLVYTAPLIVPLQLPMHKRTFLPTFHSCIVSRTYSLQLNISMAPASSTSSSTSSSSTGSATTVSLTVPIQIVVGDANDFLLMGQEAGSASSIATGQYYYDDTNTEGLPSFDDALEEAEADAHLMPRVMAVPDTQYQQTSVLPGYSGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY50</accession>
    <name>A0ABR3YY50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_006497</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19943">
        <property type="entry name" value="NirB_Fer2_BFD-like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19944">
        <property type="entry name" value="NirB_Fer2_BFD-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="entry name" value="BFD-like [2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052034">
        <property type="entry name" value="NasD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012744">
        <property type="entry name" value="Nitri_red_NirB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02374">
        <property type="entry name" value="nitri_red_nirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011565">
        <property type="entry name" value="PRK14989.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43809">
        <property type="entry name" value="NITRITE REDUCTASE (NADH) LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43809:SF1">
        <property type="entry name" value="NITRITE REDUCTASE (NADH) LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="18">
        <location>
            <begin position="888"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1054"/>
            <end position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1893320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1075" mass="118110" checksum="12EEC323BB28B80C" modified="2025-10-08" version="1">MPRRTRIVVVGLGMVAMSFMEKIMKLDAKRREYSIIVIGEEPHLAYNRVGLSTFFEHRVVENLYLNPREWYSSLEDDGSLNYHLNTRVTEIFPATKHVATSTGDVIAYDVLILATGSDAVLPTATSGHDARGVFVYRTIADLDNMMKFANEHKGTVGVAVGGGLLGLEAAKAMVDLESFSSVKVIDRNDYLLARQLDGDAGRLVTEGVRALGLDVMHNKRIATVNTDADNNVSGITFVDGEQVDCSAVCFAIGVRPRDELAKSAGIQTGERNGGFVIGEDLQTSIPDIYAIGDCACWQNQTFGIIAPGIEMADVLSFNLTEGRSGSGQPPRKFDRPDLSTKLKLLGIDVASFGDFFADRDGPKSVPQGSTDAAPLAAKALTYKDPFGSIYKKYLFTPDGKYLLGGMMIGDTRDYAKLTQIVRTQKLLDMPPSQFILGAQKEGEDDGSDLTDDTQVCSCHNVTKGDVVEAVKAGTCSDLTGLKACTKAGTGCGGCIPLVQSILNRTLKDLGKTVSNHLCPHFAHPRADLYNIIAVKRLTTFEAVMKDAGTFPDSIGCEVCKPTVGSILASLFNEHVVSRPHHDLQETNDRFMANIQRNGTFSVVPRVPGGEITPKQLIAMGQVADKYGLYCKITGGQRIDMFGARKQDLLAIWRDLVDAGLESGHAYAKALRTVKSCVGSTWCRYGVGDSVGMAIRAEERYKSIRAPHKIKGGVSGCVRECAEAQSKDFGLIATEKGYNIFVGGNGGAKPRHAELLAKDVPPEEVIPLLDRYLIFYIRTADRLQRTARWIESLPGGIAYLKEVIIDDKLGICADMEKQMQKLVDGYFCEWTEILADPDRQRVFRQFDNTNESVETVEVVVEREQTRPAYWSQESATEDFRGHRWSQLVWEPLIETSHFDAEGRSSAQVKRGDTQLAVFRVRGRYYATQQMCPHKRAFVLSDGFVGEQASTEASKNGDSNGDSNGDSVSKYWVSCPYHKRNFDLNGGTPGKCSSDDSLNIATFTAEARDDGWVYLKLPPVDELDTLLGTSRWKTRKEEAVDPFQRLDQKLGKCEIGRKGRKPADRQPPALKTVSIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYW0</accession>
    <name>A0ABR3YYW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="474"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="912" mass="99808" checksum="BCBFEFCA23CA8C25" modified="2025-10-08" version="1">MSPTAQSSSQNPADVSETPETHPDAGQESQPDTRSDTPAEQTAPAAASTTQETTETADTSTIETSAETSCLGCRRRKLKCSRDLPSCTHCQRLDVSCAYDTKKAKPGLRPGAIEALSQRIEVLENALARGRGGALTTANTTPAPESSPNLSSNAGVVSILAVLAQELQKFNTATAANARTAVSAPAQQLPPPTNGIAHIASPLSTASSPMTANGRNHGHSDRPRKRRRMVDSCGNPDIDLARPLEDMAEDPAMSPGLPPPAALQAVVNAYFVAVQPWIPVLHETQFRRRMHDPEQRPQLACLLHAMVVAAARYVQPEDLLEEEGDIDTLLRLAQRSRSHVLLVAMDSLSVESLQALIILAFHDIGSGRTARAWSIVASLTRTVDYLGLNTEAEDENSLEKQQQHTLLRPMNILGPSTNWIEEEERRRVFWCVLLLDRFCSVATGWTTGLAAADVHRRLPADGFFFHKEEPVLTPYMYGSPPGGPPAGDADRARDREVRDRDRERERERDPADPPVRSPASTHVHGHNTNVGAFAYCIEAAESLSRVVSTFLRQSVDFGSRPDVSRWLTRFKELDLQLVHWKMYLPQRWRDSNVSRQPTLVNMDPNLTLAHITHNTSTILLHQRIAYPDAAWWARWTTMVKVKLPSVCSAETCQNAAVETAAITSKYLRYTPKHRPVASHGPVDVDVLPEFWSLLRSLEDMDRRWVGSSKLDQDATKKSISLAGHYAQHLKDLHRQCLASPTFVVDILGYTEFEPKDKAKPTTTTTSTASSMSSATALNGYVEPTVQASEATAVPVVAEPAPAPAPAPAPAPTQLTQVHPAAIHPTLNPNPTWPMQPLDQLSPVMTYHQHAQAHAMADNSASAYAAASVVSVPTGHTDDLAAISHLLLDQQFMDRDRVISFEDSFFAGPGRWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ86</accession>
    <name>A0ABR3YZ86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroxy-acid dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052352">
        <property type="entry name" value="Sugar_Degrad_Dehydratases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004784">
        <property type="entry name" value="PRK06131.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43183:SF1">
        <property type="entry name" value="HYPOTHETICAL DIHYDROXY-ACID DEHYDRATASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43183">
        <property type="entry name" value="HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="7">
        <location>
            <begin position="69"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="8">
        <location>
            <begin position="398"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="628" mass="66748" checksum="EA6318B2130D3E10" modified="2025-10-08" version="1">MADSRRDDGAAAGEESSDPPHADYILDRPIQPVTGMRQGLPNYGDPHFALFLRKVFIKALGYSEDALSRPIIGIVNTFSGFNPCHANVPQLIEAAKRGVQLAGGLAIDFPTISVHESFSSPTSMFLRNLMAMDTEEMIKAQPVDACIVIGGCDKTVPAQLMGGISANKPVLPLITGPMMPGSFKGERIGACTDCRNNWAAYRGGELEIEDIAALNEELAPTGGTCGVMGTASTMACITAALGMIPLRGGATAPAVSSGRLRIAEQTGKNAVEAALAKRTPQEILSEGSFHNALTVLQAIGGSTNGIVHLLAIANRHPAVHGTVTLQKLDDVGRQTPLLVDLKPSGNNYMTDLHNAGGIPALFERLRSLLKLDALTITGQTLGEALDAENFKPFPLSAQIIRPLDNPLYPSSSLVVLRGNLAPDGAVIKASASKYRNLLQHRGRAVVFAGPQDLANRIDDPDLDVDENSVLVLQGIGPIGFVSPGMPEAGLVPIPRKLAAKGVKDMLRLSDGRMSGTAGGSIVLHIAPEAALPASVLGIVENGDWIECDVEQRRLELDVSDEEIRRRMGERWLRLEGQKASRGPADVRRQPTRGYRGLYERSVTQANDGVDFDFLAADGAGVLGKGREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZA8</accession>
    <name>A0ABR3YZA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CLG1</name>
        <name evidence="1" type="ORF">Sste5346_006414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="41667" checksum="52236918B06D834E" modified="2025-10-08" version="1">MPGGVCAVLDYEVELMAEYVAEMSTRLAMGTSRAPDSFRKFISQILSSTRLPRTTILLGMNYFAKRINMMNMMSSGKLTLSEGHVWRLLTVTLLLGSKFLDDNTFQNRSWADVSGIPVRELNKLEREWMEAIGWCLYVNLDRSEDYTAWINSWRDWEAGKKRMQRLASMTLPIDTDYANNVARHGNSTVAYNTWHQEQIAEYERLTRVKRNEQVMQQNYRAAHDQQSCWPYQAQADPWSAAPLTPPDSGYGTPDYMNSAAAMNTQYDDWFNQQAQQAANRAVANGAYGANSRQQQSQQYPITANPTPYHSRNFPAKLPTYNFYGHNIWENSADNAVNGMNCMPHGHMGKQASYFGVAHPYGQPVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZT6</accession>
    <name>A0ABR3YZT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4396 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025509">
        <property type="entry name" value="DUF4396"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14342">
        <property type="entry name" value="DUF4396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4396" evidence="2">
        <location>
            <begin position="67"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="211" mass="23058" checksum="9887B19676207005" modified="2025-10-08" version="1">MATRVFLRTRPWALSQCHRLQPCLTLRPLSVRLTSTSTSSTTTCCHKKTEAPPPSPTTLTFWQSPPTWRRAGLNTLRCLVGCSAGDFAVMWYLQTHHADWGMWPTIMGLAMASGLATSVALETTLLRLGKDALPWGRAARTAVGMSFISMLTMEAAENVVDYYLTSGGTAAGYTFGEPLFWAAAGVSMVAGFLAPLPYNYARLRKYGKACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZZ6</accession>
    <name>A0ABR3YZZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045516840" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="50"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="485" mass="52206" checksum="6F0BA7FD4591F95B" modified="2025-10-08" version="1">MKSWFVLTAALAATAAGAAIDDCLAAANVPVDAKGSSDWNSDVAPFNTRLQYTPAAIVVPKTVADIQAAVKCAATNKIKVNPKGGGHSYASFGLGGENGHLVIELDRLNQVTVNPTTNVASIQSGARLGHVFTELYKQGKRAISHGTCPGVGLAGHSLHGGFGFSSHTHGLALDWMVGATVVLANATVVNCSATENSDLFWALRGAGSSFGVVHTFYFNTFAAPAQTVAFQANLPWNSASSCASGWSALQDWIQAGNMPAELNFRIFGGGYQTQIQGLYHGPQSGLTAAIQPLMSKLGTSLSQVQQTDWNGGFAAYDNGDKVDVSYPYNQQENFFSKSMATTALPSAALQAVCGYWMSQAKSNSRQWYIIIDMFGGKNAYIPSIAANASSFAHRDKLFLYELYDRVGFGSYPSNGFSFLNGWADAFTKNLADNQWGMYINYADPTMNRTYAQQVYYRDSLPRLQQIKKAVDPDQVFDYPQAIEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z020</accession>
    <name>A0ABR3Z020_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="540" mass="58084" checksum="C01FCCEA727B3EA0" modified="2025-10-08" version="1">MGSKDDTPAVAVADTQHVDVAHDDYNDNNNDPSPGILQVLWRHPMILVCCLYANVGSLMYGFDNLSLSLCLSMAPFVEDFGIMVDGAYVVPAYWQSLWNALPQLMTGIGAWGAGPLADRFGRRAAFVAAGCLSAAGVAVVYTASTRSVFLGGKMVNALGLGMALTTGQIYIAEIAPLKFRGIALSIYTFTMNLGYLVAASVAFDRVTIPNASSYKVLFASEWVWPGLMILGVLLVPETPYHLARKGKLAATTKSLQFLYGKKTPTAPILAAISTTLAHEEQEERLGGDNADTSFRACFRGIHARRTRIVLYCNGLSQMIGATFMANAPYFMVSAGLAPTKVAMMIELGIGLAIVGSAFTFATIPHVGRRKLMLGGLVLAATLFLIMGVASSVPNPTAPTPLWCTGISLQLVWLCMGPVVGPAMAIAGEVSAVRLRAKTAALGFFFNYAYSTVWNVVVPYMYNTDAGNLQGKTGWIFCATCLISLVVVWFEVPELKDLSFAEIDERFALRVKTRAFKTWKDEAPAPSKAAAMGEVELEQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1D1</accession>
    <name>A0ABR3Z1D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_005847</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF23">
        <property type="entry name" value="FERRIC-CHELATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="370"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="666"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="725"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="764"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="792"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="696"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="812"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="849"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1894348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="959" mass="107016" checksum="863134584434BA7E" modified="2025-10-08" version="1">MASHLTQDPPSLARRIYIPLTATSPPGLVEADTVDPWIKSGKYGLAFTYFAAALTASVLIVRLWHYWQDKIRQAIYKQEVEEHYNNMYMADPEWDQPPGTAATLAAQAAAANAGHGNATPATAYTTGQNSSRHFFPDEVKAETAFRPKAHMSSITFINDTLALFRWIFYRPIPDLVIFKRRFTFSSLAVLTCGFIALAFTALYCFLPQPLYWDSIQYGSPPLAVRSGMIAVAMTPWIIATSTKTNILTLITGIGPERLNVLHRWAGYLCLFLSLVHAIPFYVQPVWDDGGMAIFQALFPNNSSVIVYGTGISCLVPLIWLCVASLPIIRRVAYEAFVMLHIPVGLLYVGLLFWHTKNFLGSWAYLYTTLGIFFVCQIVRLRNLNWTRPWRMSFFVGDEAAITLMTENAIKITIPTQMRWRPGQYVYLRMPGISLFENHPFTVSSLCSEDFPSAYGDAYRDCVLVFRPYGGFTRKVLETAIEKGPFHTYRAFLDGPYGGMRRELAAFDTCILIAGGSGITSLMSQLLNLIKRMRDGKAITKKIVVVWSLKRLEAMDWFREELRICREAAPPESVTCKFFVTSATRADHRNQYLGNLFSNPGENNGMGAHHQTRAPRPLSNLFHDRLDGFVAGIASKRNSALITAEAQGDPERERELRAEDEDRITALPQQKYLQPYQVPPPPPNPPPGKHMSMTPDESLRQLEGRGSTDVKDKDIYAKDSKSVAAATFAPHSQQKDTKQKQKNRMSISGLSTLVSSTAAYTAEEEESNFHFTPHPRADAPHFNLVPPSAMRKAVEAGEVEGVDGEEIQEPGPDGDHTGMRPPELAHLRTDVGGVQRRPDATSEARPTSTFGPPSGFDFGFPETPTEFQKSLMRFAFPVPHQIDGGWSVEYGRPDLGYMLREWATGGSDGRGVLGRRTAVFVCGPASMRVGVATTVARLQAEIWGDDMLEEIFLHTENYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1R7</accession>
    <name>A0ABR3Z1R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bifunctional purine biosynthesis protein PurH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HGT20</name>
        <name evidence="9" type="ORF">Sste5346_006142</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="20"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="56892" checksum="76B737BDCA181ABA" modified="2025-10-08" version="1">MLPAALRRVTDGVTPYFCLLLAIVTLGPHQFGFHLAELNAPQDVITCHQRGIVPNANKIPGMTLPQCIPMTEAQFATVSSVFTVGGLIGALVAGPFCSREGRLLAMRLTAVVFLLGSITETFAPSVAVLAIGRVLNGLSAGASTVIVPLYISEVAPVQSRGFFGAFTQITVNIGILFTQTLGFFLSHGSAWRYILGTGIVLAFIQFVGLLGVPESPAWLAARGGDGEEGKTLQAKRILQRIRGTTVNLDDEVAHWPSAAGSAEEQALLAGAATNTTDTHLSAAEQYDVDADEGIVTVAPPSPRGPTPLGGGANKTKAKAPVGFFELLVDSYYRPALIAVIGIMFAQQVCGINSVIMYSVSLLNGMLPLNSALLTIIISCVNLVTTMLSAPLPDRLGRKTCLLISVIGQGISSLVLAFSIVYGVKILSAFSVLTFVAFFAVGLGPVPFILASELVGQEAVGATQSWALGANYVATFLVAQFFPLVNTALNNRFGGAGWVYFLFAMFAFLSTIFFWFYVPETNGKKDADEVWGRTSRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z203</accession>
    <name>A0ABR3Z203_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="687" mass="76212" checksum="8183E2EF0587E7D6" modified="2025-10-08" version="1">MDTDINHTSPPEGRPYRSHMQPACIPCRTRKSRCQTAPTITSCSMCQAHGTPCIFPDVAARRQHRGTPRRSTHSGSGGNTARHSSTASSVATSTATSTGTLTPPVSARHSQRPSRPSRSRCPSSPPPMMTLRMLQSYGTPHSVAATDIITSEEGSSYVVSPAIADDDRVFQEYLCNTSLGHSRRMVRFELNFNGHGSANGSQNDAHTRPILFGMVPRRGERETESRKLAASHLETTEKMIAPHEGDVIDLFFKKINLVFPIFDETQFRRVLTADKERISPSLLATLYGIAMTFWNYSPQLATVTRPDVRSVLVQAEDSFIAELISTPGISTIITFILNISGRPSSHHLGNGAFLGLAVALANAFGLNRDPTDWNLSPSEKKFRIRIWWLLVVYDRWCSLAYGTPPLIRSTAQDVPILTVEDISNPNSHSDQTFAASCFVALVTLTEVLYRCLEHVYNLDKYNVARPESSLFDFETLLTNWEDSLSDDLRRLVIRGTNLVGPGAANLRLAYLSVKLFIRRIQLDWDKVALRVGGDADSQYFIQARRAAEEIVDFVRELDATHFADFWMPPSAYSLTSATTFLLRSALNARRGQPAARNSPLKLARAMVDSLRAHRRDYDWDIADNCLFNCSDLVDKIEEACDQQANLDGSSSGSNNTVFDDLQNHMPVDIDMDFAALNGLFPGFTGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z255</accession>
    <name>A0ABR3Z255_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">BRE1</name>
        <name evidence="19" type="ORF">Sste5346_005685</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="677"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="272"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="420"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1894711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="729" mass="83027" checksum="EC9ADB1CF2A862CF" modified="2025-10-08" version="1">MPIATAPSAVPTRPSAVAKMEDRKRPAIADTDEYAPPSKRQAVNGGASKVKEDPNGEHHDEAWLEDFQKDAIIRQMNEYKRENATLEARIEEIQKRSTYHDDHIRIADAWVLQLLQEIELLCEGTVSTKPNSKEFPYPSALSFKDSRDFQKHIGEKTKLVKTRLETLLNKLSGFREGVQPEVTQMESQIKLLLAAQKDYALKLERLETDKEDISQQLDTATLRYIKAEKRIDRMRSAQVQKMEEKALAHVTAKPVPVENGSTDQPAASSASLDALQGKYDESLAVINKQKEQLDKILGEIKSLQDENTTFRSKKENVTEEDYARTDLFKQVRSQNEDMIKRTNHLESANKQLREEIEKLQTDRTTFRSKLDAEAQGVAGDLEDQIQVKDQDLTRIRSARDELVADVQIRKASQDQERTAFEHLKELVAAKEDRIAALESELGRLRPAEGADTTTPRAELEALSAEELRERFAKLEKDFILIQNEMPSVEKAYKKAIGLAQKKVMDFTALEERVTMLTLEKAKADQKYFAARKDMDIRIAEIRALRHQNSKSSEIIASLKDAESQSRSVLSNFEKQLADFRQANTTIVEESRQLKATNADVARRFESSKAQIAELTSLVKQKDAANAAMREQSVNQETEHEKLKVRLTHVQKDRDSWKSKCLANSSEEEEMLRKFALCSVCRHNFKNAIIKTCGHVFCQTCIDARLSNRMRKCPSCNKAFDKMDVMSAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F4</accession>
    <name>A0ABR3Z2F4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">STE24 endopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8788" checksum="6FD249CA2EF54C39" modified="2025-10-08" version="1">MTPLDKAMRSKNAFLAFSGLVTGVAIWAIWGGDMFPATEDPTGAPETWTREELRRWLAAVGAHAQDLALGWVSGNKTRQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z343</accession>
    <name>A0ABR3Z343_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MNN4_1</name>
        <name evidence="7" type="ORF">Sste5346_005649</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF32">
        <property type="entry name" value="PROTEIN (MNN4), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540147" evidence="5">
        <location>
            <begin position="18"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="6">
        <location>
            <begin position="86"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="6">
        <location>
            <begin position="200"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="32908" checksum="26162A8FB446529E" modified="2025-10-08" version="1">MRLGSLISCALLGTALADADFASVRRRLTKDMSGRAGDPPGKYFHESIFHPHYDGRFADRVLEYNEQKRALKSLVQTYLSTFADIGVETWLMHGSLLGWWWNRQIMPWDSDIDVQVMEPSMYYLAAYYNMSVFHYKTPRLPEGRDYLLEVNPHYTNREQSDWLNVIDARWIDTETGLFIDITTARYDPSHPAGEGVLSCKDGHEYRDTYLFPLRDTMFEGAPVKIPYRFRDILEAEYGENALVNKDFHEHNFDDEKMEWVPKMIRTKNGQSPAATEEEKQLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z351</accession>
    <name>A0ABR3Z351_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_005684</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577680" description="Store-operated calcium entry-associated regulatory factor" evidence="16">
        <location>
            <begin position="26"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="193"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="263"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1894710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="324" mass="34378" checksum="A1D50CD616EF4978" modified="2025-10-08" version="1">MHLDARTAWSVAIAALATLPAPAAAASSKNNKNAILLSKVQSLTLRAGKMSTHRRVAAVPQLTCTANPQRICDLFTVDTMRCTNQGSGYDAEDIQWSCTASLPPELKLGSTEVMCEGYSSGDDPYVLKGSCAVEYRLVLTDMGEKKYTELAGEAHKGSWDAKETFNWVFWGIFAAIAIWIIWMVWTGEHRGPNDQNNRRGGGFWGGGGGGGGPGPGFGPDNDPPPPYPGTKPWDGAQQQQQQQGWRPGFWTGAATGAAASYLASNRNRNNRDNTRGFYDDGYGGGRRGGSTWGGSGGAGPSSSSSSSVSSARQPSTGFGGTQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3C0</accession>
    <name>A0ABR3Z3C0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF804">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="239"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="423" mass="47747" checksum="5F195E050791C8E8" modified="2025-10-08" version="1">MATPEYMRVQLNTLAGHEYRRVSTAPTRPATADEIPVIDLEDMWFYSSRSTVMLNSRGTPDAAKKRIATAIRKAATGAGFFYVSNHGIPDRVTDEAVSQAKRFFQQPLANKMRVHSRSDPLGNGYSPLYSSFINRSETKDAKEGFNFRYLTEYDPLHQGPHANPDPTRAPGSSWTWEQQTRNLPGFNEATIAWWQSCLELSRGLVRLFALALDLPEEYFDDITTYPGSDGLYICYPGLSSEEAKEAKKKEDANKDKDAGKKDIDVGIGSHTDMQCFTLLWQDESGGLEVLLPQTGSSKRDSDPVYEWVGATPRPGTLVVNIADFLQRLSNDKFRSTVHRVYNRKQGARYSMPFFFGFNYDAECAVVPTCVDETRPAKYAPISCGMVGPCIFFRVYRYIPSNTLQWRDERMQLARSVPRPQANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3G0</accession>
    <name>A0ABR3Z3G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase DED1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase ded1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DED1</name>
        <name evidence="20" type="ORF">Sste5346_005724</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17967">
        <property type="entry name" value="DEADc_DDX3_DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044763">
        <property type="entry name" value="Ded1/Dbp1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15 20" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 15 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="19">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="241"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="444"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="607"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="684"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="608"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1894749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="703" mass="73603" checksum="D60AECCF7B777ADC" modified="2025-10-08" version="1">MADQLNMNGLNLNGDGHGPRSYIPPHMRGKMQPNGGPRGPDVAGPPPAGPGPAAFSGPTPAGAAAGPTPADAANSGLNGSAWAANNAQNFNGRAAGGNNWNNNGPRQNWDRPQSFNPNAYGGQGGGHGGGHGGHGGHGGAGGGGGGYARGSGDGQWRDGKHIAGPANPRVERELFGTPDDPSKQHTGINFEKYDDIPVEASGHDVPEPVLTFTNPPLDDHLIRNIELAHYKVPTPVQKYSIPIVMGGRDLMACAQTGSGKTGGFLFPILSQAFQTGPSAIPANQGGGGFGRQRKAYPTSLILAPTRELVSQIYDESRKFAYRSWVRPCVVYGGADIGSQLRQIERGCDLLVATPGRLVDLIERGRISLCNIKYLVLDEADRMLDMGFEPQIRRIVEGEDMPSVQDRQTLMFSATFPRDIQMLARDFLKDYVFLSVGRVGSTSENITQKVEYVEDNDKRSVLLDILHTHGGGLTLIFVETKRMADSLSDFLINQQFPATSIHGDRTQRERERALEMFRNGRCPILVATAVAARGLDIPNVTHVVNYDLPTDIDDYVHRIGRTGRAGNTGISTAFFNRGNRGVVRELIELLKEANQEVPSFLETIAREGSYGGRGGRGGGRGGGRGQGANRDFRKFGGGGFGNSGGGGGGGSYGGGGGYGGGFGGAPPNPGYGGGGGFSGGYGGGGGGGAYGNPGGGGGPGQSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3R1</accession>
    <name>A0ABR3Z3R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42041">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42041:SF1">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="841"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="880"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="714"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="849"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="885"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="951" mass="105222" checksum="A3453331CF0093C3" modified="2025-10-08" version="1">MDFHGSRAGSPTPLQVISPERVNQQQNNQNNTGFASSVASVTDKISQFNSLAMQSKQLERKTADAALKRAMVGREEAESDMRRYREEARQLRKQVDEGKHREQRVGERLEAVMENYGRAKETHAHTQALWEKEIRRARKETFKSQSAIVKLQEELKAARASTKAAEEALVHEKERSKAREQEAFQARYELVGCQEELEQTLQKVKMLEQERDAFRSLAKSEEDVARIASEGRLPLPPPDAEEEKAAEEEDAKEAEDDKEDSDMTDGDSMDESEDNLTLTIPKQRSKQPKKKGSKKAARVSSVTLLDIRSSAASEAEISELTRLWQWEKQRADRSSELVEYLEAECHLRACSCMRKRPRNSIIDSARKRPNLDIGDGADRIILSEKAAITSPTAKIRASLKPSPSKILQSNFPHISHSPERRRDDNEDEEKEEGGDAQGDQAQQQSPKQKKAPRLSTTIFVPEEGVFRTVSQQIAEEMEEAVAAAAVATMAAMPKEPEVEVHEQVQEQEAEIAPEVEVKAEAEAEIEIEEAAPPTPAPAPAETITQDTRHPFHEILDADDNRDADTTLGDVTTDSADYTVETTTEQSMYARTPSVEPPSYAQQRTSLLSLLDAPHRQEAEQPINFYVPTTQGPLPTEPARHDANIDIHMDDAAEQHEAPRTASSLLVASTSMRHVDTEMDEPASAPIRQVELDEPVVEEEREERISDVTEVAYARSHSSQSVRSNHSNHSHSSSRSSQPSRSRQGRPPSTQQQYEDRDATPVAQPQRYETPAMDESLNGHSSVRPHTVAATNVFKHKTTTTKVPLREETTDPSLAQRIMAAQRTPTNKILPTSASAGSAVYSDGEAAATPGTTDGPSFDINNPALTPTMTREECLAQIRERRGRARSAAGGSSSSSSHSSTRTTSASSAKSATTGTTTTAPGGIRRPITPGKERREVSAPVRRVASVRRVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z453</accession>
    <name>A0ABR3Z453_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="310" mass="34090" checksum="1F1F50AFFA7F1EF4" modified="2025-10-08" version="1">MTRVVVFGASGVQGQAQVIELVRAGHHPVAVSRSPNPSLNVDGTPVETAAADFADRAGVAKALEGAEIVFLNLPSTSFQKAETILNGAHVIAEEIKKAPSVKLTVFNTSMPVPDESQDIRAQDDRRTIRADLRAQGLDVISIQPVCYLENLLEGWALPPIRDEHTLVYCHKPSLRANWISHIDVAKIMISAMQRPELAGRNIPIGGPETVRLVELAEKLSRGWGVELKCNNQTVSDFCDSMGAAMRKRATIDVDRIISQMFKAYTWYNESPTDPFVVDMDEVLKELPLDKPLLTIEEWARIKPIPAKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4J0</accession>
    <name>A0ABR3Z4J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="155" mass="15766" checksum="4635606E9EA39C1E" modified="2025-10-08" version="1">MTEPENFDDELFADLYNDDEPSASRAPAPAPVQAPPPVAAAPAAAAAPEPIAQDNSYGDDGGNQGGDDYDDTMQYDDDDDDVDFNLGNGSSSNNNAGASSGTGATVAASGFQRSEETPQPSGGGGPYSGGPRSGQPAAKVGPNSKEDGYVYFLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4R5</accession>
    <name>A0ABR3Z4R5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EGL2</name>
        <name evidence="9" type="ORF">Sste5346_005097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF5">
        <property type="entry name" value="CBM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224447" description="cellulase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="60"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="349" mass="37209" checksum="3A9B00E95B59D0FC" modified="2025-10-08" version="1">MFSALTAALALAVAVYALPAARDTGAVQFVGTNIAGFDFGCSIQGACNLTQAYPPLSALGGPDGAGQMQHFSKDDGMNMFRLPVGWQFLVPSPGSPLDSANFAKYDQLVQACLATDAYCIIDIHNYARWNNQIIGQGGPTNDQFANVWSQLATKYAAQQKIVFGIMNEPHDVPDIDKWADTVQAAVTAIRAVAAKQMILLPGNDWTSAQQMPTKSGPALLKVKNPDGSFDGLIIDVHKYLDSDNSGTHTECVTDNISTAFQPLATWLRANKRQALNTETGGGNTASCAKYLCSQIAFLNANSDVFLGYVGWSAGAFSAATYELSEVPTKNGNTWTDSSLVKACIARKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5A4</accession>
    <name>A0ABR3Z5A4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="27747" checksum="5FA769B78B6CE946" modified="2025-10-08" version="1">MQHAADEGMAARARAFVQKQADEASQKGVVDTWYCITACAFAACNQGGFVADVYKAAISQKPESDIEHQQFVLKRIKESLLKTSVIFGIPRTINAFRALVRALPSPEANETESVRNHIERPADTDERGIAYMRNIFRADLDPFLDTMDKYWPDLRTLVVTTIYGYYQSDTSVLGPITTSQLNIATLVPMDVTAEVAWHMRGVIRNEGTRADLDYAFETAMAVCQVCDVRLKNTMPKPEDVINEERLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6P2</accession>
    <name>A0ABR3Z6P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF13">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="268"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="599"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="713" mass="77901" checksum="D3457D4CDFF8CA16" modified="2025-10-08" version="1">MAASSSDAAMSNLRKRRTPYTTNQNRSSTGAATKERSQTSDQISNPDQHPPQSTGIRSSVSVPASEPTEPAASFQLRPTSLDYYLRLAEKRLGALSPDETVSSPPEGRPPIIGERTIRTLSEARKRDCPGAALAAFSLDHWKGILQIWAEEVGFQYPFIDTDTLAHDIVGASRENVQQNTSPASGNSVTASTPGTNHRRHVEDTAIMILVVVAILVDPTLVSTANPLAEAIYRDVLIRTHIADVDRDDVSLMTVAASYFFLSDREVLAWRAISGVMRLLQEERVLQNYDEPHASAVASSVAAGDDRLYWSAFTMERRFSFSTGLPFAVRDTDIQHWPHFSDTSISTAYLKSMVDYCRISSEVRKLILLPAAPPAPYALTATRDFLDFRVVQWQKNLPAALVFRGVGDTFDPTRERRGEYRLRLILYLRGSQMRTVIHRKSGLAALSSGTANTTAFDPASANILALIAQDTIRILVALARDTDIYHAQHKTFNHFLETALTSLLLCAGTTQSTAFMSFLPDVMEAMALVERLSVHSPITRALAMKLRGVQNVVNAFRARVEQQAAAAQAKGDKEANGEIQDGPLTQPAILPAQEFFLNHHGQNGQQGQRGQPGIPDQTIPGLARPTTLDPSVEVPVLPPMSGQRLSFELGRFFPPDLPSQSVGSGNNGANGTNAAGPPPTNHGVDFLPPFDVNSPMFDFLGVGNILDDYENFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6V9</accession>
    <name>A0ABR3Z6V9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Period circadian protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185404" description="Period circadian protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="13014" checksum="310302C3D8CD2AD2" modified="2025-10-08" version="1">MLGSLLTVATLAATAIAADQITTVAPGIKDTTNSLINVGTGTIGSVIIETGVGDNTDNFSTDITIDAGTATGMGSNHATATGADNTQSGGTPAAATSSSAAGAAAGLGRGGFSAGGGVFSLTSVVVGLVGGTAAILAMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z764</accession>
    <name>A0ABR3Z764_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23279" checksum="9683140B3B5D6D0C" modified="2025-10-08" version="1">MERIQGESVEQLLEDCEEDPVEMERITGIVAHCLSDMVRIPVPAEFLEPTGPTGPAEPAELVKSSRPRHYVDTTAVSIAALRGQLLFYALDRKGDAAGNIIEVLFLLLERGAPLNMTMYADDPPSLGMYCFMDFGTPLHKAVDAAKLEIVKFLLAQGANMSILSSETKPTALQWAEKKGHEDVVAVLRSPDQHQLQVGAVAERKRCRPVKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7C4</accession>
    <name>A0ABR3Z7C4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16434" checksum="9E75BB636370A213" modified="2025-10-08" version="1">MALPRYCGNGGNVNRARAGVAFIFIHSVVYASFFNSTVFTVPAEYFPAQLRGYGTAIAFMCESITSVWLTQVTPVAFETITYRYYLIFICTLVALGVFCFFCVKETNQMTFESIAGNFGDEVISVDKGGAVVQDEVELDRARAVEEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7U9</accession>
    <name>A0ABR3Z7U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome c oxidase subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cytochrome c oxidase polypeptide VIa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">COX6A</name>
        <name evidence="13" type="ORF">Sste5346_004685</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase subunit 6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.95.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001349">
        <property type="entry name" value="Cyt_c_oxidase_su6a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018507">
        <property type="entry name" value="Cyt_c_oxidase_su6a_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036418">
        <property type="entry name" value="Cyt_c_oxidase_su6a_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02046">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01329">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="125" mass="14394" checksum="462670B39135459F" modified="2025-10-08" version="1">MFRAAIARRAGPAARRMYSTPSTGAAGENAFVRERRAVKEHAAGTTTLWRNISVFIAIPALAASGYNAYTLWKEHWEHWSHLPPLEERTEYPYQNIRTKNFVWGDGDKTLFWNDKVNYHNKDKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P7</accession>
    <name>A0ABR3Z8P7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_004240</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045991481" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="20"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="167"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="348"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="509"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="644"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="765"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="940"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="949"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="811"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="217"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="398"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="551"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="686"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="807"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1897036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1118" mass="99393" checksum="29A64D3C416ADB72" modified="2025-10-08" version="1">MKSSVIAALMGSSAVMAQAIVPPACGPCSAFISAVPACATDCIVSAAVTNAGCSDANYPCQCSNAAAIQNAAINCVIGGCGFATALDVLPAVSSVCNCVTTSGCAAASSSAPPSSVPSSVPASSSAASSSAASSAPASPSSAPSSIPSSSAASSSAASSSAASSSAASSSASASVSASASVSAPATPVCTNCEAEITAVPACATDCINSAAVTNAGCVAGDYSCQCASADVIQNAALNCVIGDCGLATALNVLPAVSSVCDCVSTSGCGGASASPSVVSSSSVPASVSASASASASAASSSESCSEEASSSVAASSSASASASASASASASASASASASAASSSVSAASSSPSASVSASASISISATPVCTNCEAEITAVPACATDCINSAAVTNAGCVAGDYSCQCASADVIQNAALNCVIGDCGLATALNVLPAVSSVCDCVSASGCGGASASPSGSSSIPASVSASASASASASASASASASASASASASASASASAVSSSSPASGSASASASISATPVCTNCAAEITAVPACATDCINSAAVTNAGCVAGDYSCQCASADVIQNAALNCVIGDCGLATALNVLPAVSSVCDCVSASGCGGASASPSGSSSVPASVSASASASASASASASAVSSSSPASGSASASASISATPVCTNCEAEITAVPACATDCINSAAVTNAGCVAGDYTCQCASADVIQNAALNCVIGGCGLATALNVLPAVSSVCDCVSASGCGGASASGSSVPSSTPASVSASASASASASVSGSGSAVPTGPCTPCAAQISAVPTCATACINSAAVTNAGCVAGDYNCQCANAAGIQNAAVNCVLGGCGFDVGLAVLSSVSAVCDCVSASGCGGPTGSASGSGSGKPSSTPASVSASASASASASASSLPSGYTTSTIFSTTTSTILSCAPTVTDCPVGHVTTIVTAVTTTVCPVSGETSPTGGSGGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGANNGTSGGSATTSYATNPTTVVTAAASKGSLAVVGVFFGTLMAALML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8U1</accession>
    <name>A0ABR3Z8U1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004281</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11387">
        <property type="entry name" value="bHLHzip_USF_MITF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051732">
        <property type="entry name" value="USF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117:SF3">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="285"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="328"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="480"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="56078" checksum="05C9B5A3A8A7B4C0" modified="2025-10-08" version="1">MAQHGFGQMGGGNGAIDPNDLAGGFGQSFQNNFGSNQNNHSTGFSSGAALISDDDLFDTLGSPGDTQSGLGGHDFSGMTSVGLGGGYSQGMFAQHGLSLDQSQLNGYSNTPEGDPIQSPFVNSMGQYRSMHNPHAFGSLQSPGGYTGSPLAASNFTGDDANEPNYIKSRARLSQSMPRKATTTRNPLNSKSIGGTSIPTTSVDSFVGSPQPIRTNGSNHEKSSSGQWAQTPNSLSSFPGSGFSSPMQPGGLHSAQINELLLKGGTSMPAKLGAPINTSQEAKRKRRRESHNLVERRRRDNINERIQDLSKLVPSHRLEDEKIKKLISTGTPLSPTLTGMASPSQATSGLAGPGARRAAGASAGNITTGLPIEEKDKGPNKGDILNGAVSWCRDLMWMLDTYVSRQEELIEYFNDRGEPMPFTISDDERRLTSELMIAMRNPDGAEGEKKHFTYSRTDGSGLRVPDYTDYKGDPLNGSGQVDSLSLMAGNDGSGGIVTQDLDQGDFWGDDDDGGDMELKEEDEFMDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8V1</accession>
    <name>A0ABR3Z8V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_004626</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006102">
        <property type="entry name" value="PRK08256.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
        <property type="entry name" value="NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="11">
        <location>
            <begin position="265"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="463" mass="49537" checksum="03C05751C4B13D25" modified="2025-10-08" version="1">MVKAKAPVYVLGVGMTKFIKPRGKVDYTELGFEAGVKALLDAQINYDDVDQGVACYCYGDSTCGQRVFYQFGMTQIPIYNVNNNCSTGSTGLYMGRTLIGNGGADCVMVVGFEKMMPGSLQTFFNDRANPTGTTTEMVRATRGLTKAPGAAQMFGNAGREYIEKHGAKPEDFAEIARVNHEHSVKNPYSQFQDVYTRDQILNSTTIHAPLTKLQCCPTSDGGAAAILVSQAFLDARPHLKGQAVLMAGQSMCTDDPSLFSRSAVDLMGYAMSQRAAREATTEAGVTPNDVQVVELHDCFSTNEMVTLDAIGLPEGRVGGARGGAVELVRRGDITYGGRYVVNPSGGLISKGHPLGATGLAQCAELVWHLRGWANNRAVPHTRAAMQHNLGLGGAVVVAVYKRADGQEAPVLDDATVGRLNKLGYNPATQAKGFTAEQARSVRSKTKASDWALGDTEAKVEARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z943</accession>
    <name>A0ABR3Z943_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="763"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="799"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="904" mass="96975" checksum="7161B42C7A963827" modified="2025-10-08" version="1">MDSEEVAHSRNSTVSPSAAPAAPLSAIVASAKTDLAHDAIAALAARRTSPANSGSVSPGGHKDDKDSAENTIHASGLSPPPPPSTSSTAQPSNERPSTGHREQQQPSPVASPPQPKVRRPLPSAAPADLAASTGLIPGFPRRESTTSYATGAPSGHQDKMPAFDRDAQDPSTGPVNSTSSRHSITNGDRPPMNTNGHFPARAYEDEIIVDTKSNSLQQSSPIRVASEHEDVPMDDANARDRSPGSYNKRRRSSTLEGVDESSRGRVSPTYEGGGHFDAWRQTAKAGTAQAASPQPQNAHAKSTPLGYWRDSTVPEAADRHAVIGFIDTRDRLRTRVHQFTRSGKPVSPKYPFPPGPGGSWVTFERVVFEKHLIGMDHNQIKEYVKLRIDALGTPETPEEAALAEKAAVKEAMRRAALHPVPDNQPPPQIAYGEDLPDYVVNASRPEKKRRMGSHYGVSLPSMDPGPSALDSPLPSNGHLAQAGSASVVSAIQRSAIDLLPGTRPTRILLGYWRGSSEERVEDKHAVMGILGANDMFRVKVTRETRDGRSILGNYPQGAGALWIHYDEVEFEKHIRHLSRPEVKEYVRVRQRQIDEGEKPSERSANEAKAVYDAQARVINAGGAAQSTLGTSGRLDTISFATAANLNREAGRIIDRHDPGAVAGAVEMNGISPSPYLDGPQDGRARRESSGSELRQSRRSTLDVREPPVSTSINNVVASGGGPANPLAPRGARHSLPAGPGLAANRPPPVNDNADRVERTNSLARREITRMESIQQRNEQRASNSYHNGALANVTNAVPSQHNGIHATNNGGGSAGGGSSADEGKSSSRQTFSENIGRLNKVWASQEASRIRSTGNDDTKIYMGVKYERKPTGPFQGKLVSPGTILSIDGEDYVEYRVLTKPTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG8</accession>
    <name>A0ABR3ZAG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43060">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43060:SF17">
        <property type="entry name" value="L-THREONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="1">
        <location>
            <begin position="6"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="2">
        <location>
            <begin position="182"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="2">
        <location>
            <begin position="319"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="46073" checksum="B74C04B319B5F125" modified="2025-10-08" version="1">MSTKPDVAFIGLGAMGFGMATHLVKVGYSVTGFDVWQPTLDKFAAAGGKTATTPAAAVEGKSVCVCMVATAQQAQQVLIEGESSAATALPQNAVILLCSTVPCGYVESLAAQLADPNGPVRRPDLLLVDCPVSGGATRAADGTLSIMAGASPEALSNEAGRTVLSDLADPTRLYILNGGGIGAGSNTKMVHQVLAANQILSGPEAMGFAIRLGLPPNAASLEALLASPGRSWMFGHRGPRMIDGFQPLASAVTIILKDTAIITSEARRAGFPTPMTGVVENLLYTALGRGYGGDDDSSLLRLFTEGAPTPSSTETSPESVKLVVDLLKGIHLASAAESLAFAHFVDLDLDLVLDLCINAAGGSAMLEAYGPSIVAVLRGEPAPAPKGDGSDTETLADIYKNLAHAVDAAQQIKAPIYLGTQALNLLRLALRKTSSDNAPASAAVNVWVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG9</accession>
    <name>A0ABR3ZAG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-tRNA hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046467658" description="Peptidyl-tRNA hydrolase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="28292" checksum="FDB3A706929C0F0E" modified="2025-10-08" version="1">MRFSTTSALLALPLLGAAAEDGGLFGQYKAQFQNLLGSLGVGAPEAATGESASAKPAAAGGAAPAAGTAATTPTELTLGNWERTLYSTVKPDATTPEEWRILITGRNKTCFGHCAVIESAFYASTIKTAATSDAHTGIINCDDQPVLCNSWSTSPGYLYIFELLPKPANTDIYIKRLNLTTTTPETLITLYEDKERTSYHTLGGYFHPLDGQLAQNGLAVPIGYVLWFFNAVPSWMFMIGVSFVSRTFMGRRAPGAGPRPGAAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAH4</accession>
    <name>A0ABR3ZAH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PWP2</name>
        <name evidence="7" type="ORF">Sste5346_004558</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="147"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="344"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="386"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="472"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="6">
        <location>
            <begin position="750"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="636"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="912" mass="100990" checksum="BDDF9A87B73063F8" modified="2025-10-08" version="1">MKTEFKFSNLLGTVYCKGNLLYSPDGTHLYSPVGNRVTVFNLVDNKSFTLPFAHRTNITRLGITPRGNLLLTIDEDGQAILTNLPRRVVLYHFSFRSPCTALAFSPSGRFFAVGLGRKTEVWHVPSTPDTNADGELDFAPFVKYRTYTGHFDTVQHVEWSGDSRFFLTASKDLTTRIWNLEREEGFTPTVLSGHRQAVVGAWFSKDQETIYTISKDGALFEWQYLKPPRPAGEESSDDDSEDDEDDSDMRWRIAQRHYFNQNNTNLRCAAYHAASNLLVAGFSSGVFCLYEMPDFNLIHTLSISQSDIDHVTINASGEWLAFGASKLGQLLVWEWQSESYILKQQGHHDSMNALVYAPDGQRIITTADDGRIKVWDIESGFCVVTFTEHTSGVTACEFAKKGNVLFTASLDGSIRAWDLIRYRNFRTFTAPTRLSFSCMAVDPSGEVVAAGSVDSFDIHIWSVQTGQLLDRLSGHEGPVSTLAFAPDGSVLVSGSWDRTARIWSVFNRTQTSEPLQLQADVLDMAVRPDSQQLALSTLDGQLTFWSIADAAQVAGLDGRRDVSGGRKISDRRTAANVAGTKSFSTIRYSTDGSCLLAAGRSKYICLYSVTTGVLLKKFTVSVNLSLSGTQEFLNSGKLTEAGPQGELDEQGELSDREDRLDRSLPGSKRGGDPSARRSMPEVRVSGIAFSPTGLAFCAASTEGLLVYSLDSTLPFDPFDLSMEITPATTLQVLREEQDYLKALVMAFRLNEAALIQHVFLEVPHQDIPLVVSGVPTVYVARLLRFVAAQTEQSPHIEFCLLWIKALVDRHGAWLTANRGKLDVELRVVARAVGRMRDEIRRLADENVYTVDYLLDQAKARQAVKKLAAAQPATVALVITQKADKTKAIEEPRAEVVVFDDGSDDEEGWLGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBE7</accession>
    <name>A0ABR3ZBE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="365" mass="40981" checksum="56EB24108557D7BC" modified="2025-10-08" version="1">MGRPEFPGLFIGDDKNDDAKRKDSNKGAPLEHVQIDIGMWSFLYQSWNTTNLRRLHIQWTSDAGHALAALAFRGELASVETLWLAGIHKSSDGTCSDIHDIIGHIPALHDLRLTGNVTNAIFDTILHHHNATIRSLYLQPYEEDEFEEGHVDDDSGQLFAWSPTMIQQLTENCLLLEAVFVEVARTRGDRNEVALYRALGTMPHLKHLLLHLICPLDMGPGSEELDGNPTKITADAHKTTFTNAAVDKTLARSIFNVISREGQGCLQTLHLIPEFHARYHTGYTAAVRALTLPWACTRQANGEVVVEAIHKRETKDTIEECAGMIEGNKLCLKGQEEIYPYVFMELWPGNEPWWEGWTSLPLDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBM5</accession>
    <name>A0ABR3ZBM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="34623" checksum="546CEAFE1F74AFD4" modified="2025-10-08" version="1">MAIKVVFGGAALGNRPPFANDEDLLKAFPVLKDNGATSIDSSQVYGNSEAILGRTKAGEQFKIHTKWGVREAYGNPEITWATKDFILKSARESITRLGVKQVDIFYLHFPDPGTPLEDTLAGVDAAYREGLFCRFGVSNFTAEAVQSIHDIASAKGYVLPTVYQGQYNPLARHFETDLFPTLRKLGISFYAYSPLAGGLLTKTLEDFKAGKGRFTEGSPFYHMYNKPSYLASLAHWEEAAKAEGVSRAELAYRWDAWHSILKEEHGDALIVGSGSLEQLDETLKWVQKGKLSDAAVAVIEQIWEDVKGEGPIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBZ5</accession>
    <name>A0ABR3ZBZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003562</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="21"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="423"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="519"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="547" mass="59752" checksum="0BA6EE908AFA66BC" modified="2025-10-08" version="1">MSSFTTEAFTLLGIGLGFIFLRTYARLTKTGMSGFKADDYLMLLAAVVYAAETTLAYTVGAYWQGLANNGMTDAERKALSPDSEEYRLRVNGSKTQVAGWSTYTLLLWLLKASMCTFYLRLTEGLEYQLRIYVGFGLIFTTWVAVLLSILLGCRPLSKNWQIYPDPGNFCQPAISRIDIFVTVVLNVLTDIYLLSIPLPMLWKANLRPAKKVGLMILFSGGIFVTTAAILRCVLIITNPVTGAQQAGSWACRETFVAVVTSNLPMIFPLMRRWGSPLFSSMRSVSARSKNTGGKMSGGNNTGGTGRSVNGMFILEDKNPRRGMGPRSVNPLPNMTFSESEEQIYNEQLQQQQTDLEQLQQNERKQQRRSRTSKQSGHNIDIEHQALSSRPSFQAASSSSGTGSAAVATVVRSGITKQVVLQITEEERQRRRSTFGASGTGNGASRTNNASDTDSGNSMDMLEAMVPGARQGNYFLTENNTSGIQQKQRSSNTRSGDANSLSTSAQSAASPLAATSWDGKPTKESIGDMSVDDTKRGSMGLTPSSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC10</accession>
    <name>A0ABR3ZC10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="403"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="68242" checksum="98C97FC9153F8A02" modified="2025-10-08" version="1">MDDALHIRPVKTDGRSSTSASTSSRAAANLSMERLYRKRAIDRENQRVLRQKNKTRLAELEAEVRTLTERLAQAESDKAQAAARTQTSSTSLDGIIASLRSLQVSLAVATAASSTGGSAHGSSPRSSPLTTTASPVSNVAARTTSASSLSPSPASLQPDGKHGQQSQSGQPVDQPMSGTQPYAGDTVTLNLDNLDFWGSGASVTVPVEDSIPFQNSDFSLDIDLLTRSLPLFSVDLPNSQQGQHQGQRSNQHPSHHQHPPNNAHSARPPRPPTPTQLHPHLYPQFPNQLPPLASEPQSGYPFTQGYVHRNPPGSIDFTAASPPAPSAAGDSFRRNPHDDTGAVYLARVEANRLRDASPVWAVTPPYVPPTSNVDELIINLVYKRRRGQAVAAPGATATLTTRSLSTASATTAGTSTSAVSTGSTTPSAAASASTAATSPSDEFTHAHFPSVNSLLNPVLYEPDRPVASTIARHVAGTIMVYTTPEKTALLYMMCIYIRWLIAPTREHYDAIPEFFRPTGAQLVVPHPFWIDTLGWPRVRERLVSHLDHTRYRDFASIIVKSFSIGWPHHALEGILEASPEPTADGKATNYVMTKAFVQHVREPKNWTVGPELVEAFPFLEGAVNVRGRPPVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ8</accession>
    <name>A0ABR3ZCQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028209">
        <property type="entry name" value="LAMTOR1/MEH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15454">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01262">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17573" checksum="B3876001D7ED2EB2" modified="2025-10-08" version="1">MGNCSSCLGARRRSVYEEDDESRLLFDDADGAHYGSFGEPTMNEQDDAQESQREFEALQSVVARTSDNMVDVFEIAPPRPNPNGVPAQYAMGIPDNRFAQYQNLLSKLSVTDDADPDARIEEFDIETTQVPQVYGESLPTKADVAGPFVGNFTDAARVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDJ0</accession>
    <name>A0ABR3ZDJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="2">
        <location>
            <begin position="266"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="459" mass="49122" checksum="1047D6ACC930AB56" modified="2025-10-08" version="1">MASQQAKPGGVAPATPTTRSSGSGARSALFVAAAAYLFISLTYQTSQVLGFTSLSVSNLPRPAFLQPKPAPVPSQAQVIDQRSFNALPHVPPSTEFNGTSKPFVPPGHTVDSLKERPFHVYDPAFVALLGSDPTLTRIAVSDKDPLFHEAVVWSRDTEEVFFVQNAGAPDAGTGLAKSAIIQKISLADAQAAADRKKAGTSDAGTLIPVTVVDSAPQVINPNGATNYRGQILFAGEGMGPNIPSALYAMNPRAPYNTTVLLNNYFGRQFSSLNDVAVHPRSRDVYFTDTLYGFLQDFRPAPGLRNQVYRWVESTGAVAVVADGFTLPNGLTFSPDGRYAYVSDTGMHHGLYGFEYRDPATIYRYDVQSDGTFENRKTFAYVDSVVPDGVHCDDKGNVYAGCGDGIQVWNPSGTLLGKIYLGMGAANFQFAGPGRMVVCAETELYYVTLAAVGAIVESEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDJ9</accession>
    <name>A0ABR3ZDJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003572</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="839" mass="91356" checksum="70CD5189B2A2D3A3" modified="2025-10-08" version="1">MQTTGFRACESCRALKVRCMPADGDTGNSTGINGTLSGSNTPPVVLPPVSERAACRRCKDTGTTCVYTEPRRTKRKRTDVRVRELEREVRMLSELLMLRRRVAEEGMPVSEYERAQTSARASLAAAAAAVTPPPAQQSLPNTPSALFTAPPPPVYNTETPYSAPSQAPPPPQAPPPPPAATAAAAASSATMNMTVNGTLEADPVIAGILSMDKAVRLFRRYVTMMAPQRPFVVFPKVTLSSELDMTPAIEASISVVAALVREHTPVLFLSVLTAAMGTGFDEDSTHGSPDGSSNNFGDNSGKQEDIATLLDSLLLRVYADRIIYQSEKSLELVQALLISANWNFYCFDKPFSNNSRRADDETSRQNGATSNVSSFDHLRFYQHLHMAATMAIELEPEYHEKGSISTGRTGGGVVSGLLEDPVAFERTLLACYMCCSSISLGFHRQAMLSFTPTMAEYLRRLETSPHAASTDAVMVAWVHLQRLADTTAGALGLRAVVCNRSGGAATLADNTPIHGYDEVPDLSDPKIQASLKNVTRQLEQWRLDYSRVMTNSLLIQYNTILCLLHESSFYNEFAASDLKPPYRVSIPGTFNDMPTRQPLTSAHLASRRICLMASRSLIGLFLASPTEQLLGSPVVVYARVGYAVLVLLKLQISAALPGGAMHGLLIDTVTGDSATQIYQYLESLIARLEELEALGGRIASVWMSMVRIIHAWYEAYFIPAASGRGAEVNSDVDPILEPLRHCVQSSVVQPAYTITPDVVKQKVTPEMLKQHPYSVTDQGFSSLVSDFGTSVCSMLSTMSRDEEEAFLSSALDTGEIDRWMDPRIGLGDIQNRLFEFSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE28</accession>
    <name>A0ABR3ZE28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Translation initiation factor eIF2B subunit gamma</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GCD1</name>
        <name evidence="16" type="ORF">Sste5346_003337</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 16" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="14">
        <location>
            <begin position="33"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="15">
        <location>
            <begin position="516"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="347"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="598"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1898926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="635" mass="66887" checksum="749BFD154C26EEA9" modified="2025-10-08" version="1">MPHAVTKGSGLQALILCGPGSSFPTFTANPDENPKALLPIANRPMVWYPLDFCNRAGITDITLICPPSASEAIKAALSTNPFLTSLPAPSVLAPKDLDQTTGTAAILRLPEVRELVTTDFLVLPCDLVCELGAEKLLQAWMVKAASLADLLEEQDLGRNFLAEGGVSVNTQSKPIGSSSSANGNGFATHSGGLGVWYDTRTGIPTVKSEEKDFVATVPLAKTPSHAAGTAAGAAGTSDSKTAPSVVPYLERVVTAMPTDSLNDLNEEKNGYPTRQGLLRRHRGLRMRTTHRDAHIYVFPHWIMDFVQANEHMDSIGEDVLGWWAKAEWQHGLPEKLGVGKALQTYCAPSGGDNSDSNSSNGGDGHHQQSSSASPSRSRVQWARSLTSGAGPTSAAATFVSSAPVTAPLTGADAAGSTEATAATAADEDQRQQMPPLLAYVHPSSATAPLIRRVDTSQLLLTVSLQLAKLPSVEEVALASGVAADSAAALAISSPFAHTKKVAYPEGVKPRTTVTRPDSLVADNVTVEEKVSIKECVIGANCQIQEGAKLHQCLLMEGVVVGKGARLTRCILGKRSEIGAQSVLVDCEVQENLLVEPKTEEKDNNFMSSEGLEATAEEMDEAMQDVSDDDVAVGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEJ2</accession>
    <name>A0ABR3ZEJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF10">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="192"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31163" checksum="4A64B7B83DBE5BE1" modified="2025-10-08" version="1">MAAEAGHEAVMWTLLANGAEIDMRDGTECTALWYAAKNGHKTIAQLLIEKGAFVDAGDYENNTPLMAASEAGHVDIVRLLILDGANVHARNNDGTTPFMRAATEGFVEVALLLVDNGARVDERDMNGWTPLMHASNNAEEAMVRFLLEMGADTNATADGSYAPILCALDVFSANIRQLLLDKVDDVNEVSNDGQTLLIRDAQEGYRALKFTQTLLERGADVNARDSYNRTALWHAVNFGSFEKVELLLGYGAAPDIQDKAGNTPMALAKEYGDTGMVELMEDYLAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEK2</accession>
    <name>A0ABR3ZEK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">OTU1</name>
        <name evidence="9" type="ORF">Sste5346_003000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="8">
        <location>
            <begin position="125"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="327" mass="35647" checksum="480165914073E0E8" modified="2025-10-08" version="1">MAPIRLRVRGPSAVVTLEADDEWTLAKLLALIREKTGVESFTLKSAYPPVALDLSDAESKTLAPLKLGGETLMVIPTEGGLAGGPSAAAEQIPAAPPAPKPKPFTPKRVDVDETVVPWDEGGGYLVLRVMPDDNSCMFTAFGGVMGISDPAAQVRAEVASHILANPDKYTKVVLEDTEPSVYANRIKDPQRWGGSIELQCLSEIYGIQICSIDVKYGRVDTYGLDKDTRCILLYSGIHYDRIAQSFDLGLPVDMDVTQWRVDDDSVIDKAKQLAAKLKSAHYYTDTQTMAIRCEMPGCENWLGSGQKDMIKHTKETGHTAFSELSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEW4</accession>
    <name>A0ABR3ZEW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="18916" checksum="A2FE596444345CE1" modified="2025-10-08" version="1">MNGTHPHCDRPNAIALAFVDSIASSAESSRTDDGTTSVTILGYTALGLILVAGVAMLCYWIYVYRKGNSAGKKGRPAPAHIVSFPEFMVQAKGRNSLGSSVRSDIGTNMSIAISGLSTVHEEPATVPAPKSAMAPKTSVKKPVKKSVFFTPEGLNRLEQRLSDQATRYQLSCDPSEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFB6</accession>
    <name>A0ABR3ZFB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitronate monooxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="40639" checksum="27A6A8EFA943573A" modified="2025-10-08" version="1">MASPQKIRTPITDLFKINHPVLLAGMNVAAGPLLAAAVTNAGGLGVIGGVNYTPEMLRDQIAELKEHLTDKKAPFGVDLLLPQVGGNARKTNYDYTKGKLDELIDVVIESGAKLFVSAVGVPPKHVVERLHKNGILYMNMIGHPKHVKKCLELGVDIICAQGGEGGGHTGDVPTTILIPEVVRLCKGHKSPLTGLPVQTVAAGGIYNGQTVAAALMMGASAVWVGTRFILTDEAGAPESHKEAVRTAGFDDTIRTIIFTGRPLRVRKNPYIEHWETERQDEIRELTSKGKLPYEADLDKVLSGELSSPPSGKGDEKKDASSSDDDEVDIDELMDQFRPFLMGQCASVVNEKKSAKAVVDELVDDAVVSLSQGQKLVAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFC5</accession>
    <name>A0ABR3ZFC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003313</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056681">
        <property type="entry name" value="DUF7779"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF7">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25000">
        <property type="entry name" value="DUF7779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="449"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="596"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="630"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1453" mass="164859" checksum="84086A6DB9E11897" modified="2025-10-08" version="1">MYDALVKRRPGIVKAVIAARYENVSQTFNKLCSNFIPFAQLLPETETQNQALDDAFARLTTWGHETGAEDQTLDYKLRKSKDLHETVVEALHELQVSLDEALQLLEDEKLQEWSNRATDDPGDRSLPPITALPENESGTSSRDELVPVSVDGVSLDDAETASLLEMFSDVFDFIGEQVENLIMLGPSLDRPYPQDIDTYSSSISNTSDISDQLDIERAKLEFPSASSILKTRLGRANWRRRVAQMAVQEQIQQDGKIHVAKKGSKKPHHHDVAQDAFNFQKPTLKLERRQPIQKAPMFLPLMSAAASSTAQSDTASIFDVDSIAPRLNRAESATTLATMATFNSKKFQMAGSEMLQQPPAREALFPKMPLQLTELPKGKTQLFTCNFCGYDLEAGGKIKTEEDWNEHLLEDLEPYLCTFDKCFSAQETYAQRDEWYRHELESHRIKKTWPCPACMKEFDTKSEATEHIVQTHCRELEDEKEVAMMKAMLRQTLSGQHVGTQICPLCGDKVEATACKDHIGRHLEYFALLSIANEDASEEDDSDDIFSQSDDAMSERGRKEFVLNTFVTEQFKLNLERGKQPPDLFMDGTSRLDLLDDMSDYDGSKDSDSRAGGGETRQMLIDRMFQTGSNTSVGKKVAGERDTPTRRMTTSTTNSQKTRQALQQVASPPSLASSTEKLPLLRTFASPRNSDFMGRDKELANLYKILSEPGRVCVVSGEGGMGKTALAVEYTWRFEQSYHYIFWVQAETPVGSSDTFSQIAQQLQLAPDGTDQDTLIRLGREFLEQIRDKRWLMVLDNVDRWEDIDVYTPNKTSATQGSILITTRHESLTAPSRPVNYFRIMLQELDVEEGRKLLIYGLPEELRPEEMSLRDPEYKVAGEIAGLIGLPLLIVYVSGYIKKFGCTLSEFWEYWNEWRPKARLAGNTGNAAEGGAVLDTSGRDSVLYMALRDLSIDEMKLLKIMAFLDSNGIQREVLEWNNPNQPGPAYLKKSRLRVIISKLKSQSIVSERKQGEREIYTVHRLLQSKLLQDMNGNRDERDIIFGIAYELIRNRLPRPSLDTPEQAKWNAFKEYLPHVLSLQRAYADPLSIVNVKPFLGLAELFKDGGVLLWQRYIHGDALRLLRSAERVLDQLPQRDENLRSEINITINLLLQYFGISHRKEIRERSAKILEYRESMLKQRRPESVTNEDKLVLNNARADYANTLLQFNDFRKAEPIYEECLAIYMEIGKAEDGGTAFAIAKLHHHLAYCKMYRRQFDEALALSEKAAHIIESVSDMAMTMRYRFDLACIMLQSGNLQQALDMHQDILKARLGFQGRASYFTLQSQYAVAALCHYMGRLEDAEILMKSALGKAAGRGGKNFWPEAAVARTKYHLSMIMTERIQAEGENAQTSKRRDEARKLAIEAKDVLSRMLPYDPEPITGVREEDTLALFDHLQPVFGGRFTGTKLLDYVSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFI4</accession>
    <name>A0ABR3ZFI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="295" mass="32349" checksum="2B19E73BC30BE1EE" modified="2025-10-08" version="1">MGDTQTMPTQPAPAVPTVQIAPSLAAGTAEILPLQSVDAENIGPCRESRTSTTTPSSTDFKGRAAFRESSNRCFVCFEPCVTGSAAFLRTRQDAWAMVCRLTVNGVRVGPGEPFTSVVRGTHYARPSAFDCSSCSASVCVLCLCRRLRAGIQYVAQHPLTCACGEVSLVNETTVLFLTPEQEHSLYLRCDEWYCSDPLYCPVPTCSAYIPMLPCLLHFGRSKRASNSSSGELPTRVSCVKCDVPICTQCKGRADDEAHRSDDIAQNGKPVPCMRPNIHHNKDIERFIQEKGYRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFY7</accession>
    <name>A0ABR3ZFY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF18">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="12"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="431" mass="48239" checksum="7C6218BA9639AB9B" modified="2025-10-08" version="1">MADPAAGRPFKKVLIVGAGPSGLLLAVLLSQHGIPVHILEASHELDQQPRAAHYGPPAIPELARAGIMDILEKNGGMRLNSMYWRNFSDHTQIAGFDGSVLKDAGNVETTLTEDLRTACLPMQDLDALLLNLFVTKYNGQVSWRHRVTKVDQNEKSAWAEIEVLAGDLDLTKATVSETLRIEADYVVGCDGANSIVRRSLFGDDYPGKTWDAQIIATNTYYDFAGKFGFNDANFIIHPEHFFMAAKITADGLYRVTYGETPGLTREEYVERQPWKFETMLPGHPKPDEYKIINFSPYKMHQRCATSFRVGRVLLAADAAHLCNPWGGLGITGGFVDVGGLADCFIGIWDGRAEESILDLYSEKRIEKWKTIIDPISSENFRRVSDADPTTRLGRDEWMQLCKKAEGDVAYTKELLMGFMDVRYDFTQHYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHG6</accession>
    <name>A0ABR3ZHG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-binding transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CRZ1</name>
        <name evidence="10" type="ORF">Sste5346_002904</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="383"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="679"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="413"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="705"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="736" mass="78374" checksum="CA09F7C6F2A4A8C9" modified="2025-10-08" version="1">MDQIQPSRGRSPAPVDQQGLDIKQSHSPSHSPARNFDANYQAAVSNSNTLGLGLALDSSSQQAFNTSQPQADLSAYNGGAATFLATTQPGLQQQDLAFDPSLSFADQLKADPAGASFSQGFLDPQQAFPQEDFTIFPTSSADQLSTPLFDQQQQPQTSDINAMATSQAHHSPTPPHLLGVDALAAGSAHQSPSFNNHQFAQPVGRHSRNTSLAPEAALMHDWNAPHFQGHRRTASEYSDASSIGGHSPSIVGQDSFADSIQHQQSSPMLRAEENGDVYQELHGINSFSISSGYVGRSPSHSPAISPRILPQSVPDVNQASGNFILQAPNDGTYASYPYGAVSGSEAFPQLPTTSADMAQPIPQIAPTIEIDFAPTTVVSRGMFDGKPMIDTDALTPPEQRGRARRRAITDPYSGGAASNVSVSSLSPNVGSSPRSDASRSLSPLERSGSAVAGNRRRLSTSAVPNNIMALRLADPEFAAANSGEAGAAGGAVSGAGTKRAQKHPATFQCTLCPKRFTRAYNLRSHLRTHTDERPFVCTFCGKAFARQHDRKRHESLHSGEKKFVCKGDLKVGGEWGCGRRFARADALGRHFRSEAGRICIKPLLDEEFLERQRVWQEQHMQAQAAAQQNMMMAAQPPPQIDPNTGYPIDAAGNYALPAALLAQYPALAQVNWSQVDMSGTGSGMEDDLSGRSSFDASDFDDGDDGGYVSGPGTGFGEGSMNENYGDIGYNSDLGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJP4</accession>
    <name>A0ABR3ZJP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF66">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="291" mass="30494" checksum="688E2A6096DE1C36" modified="2025-10-08" version="1">MAPKDYPAIHMVAPDSTAPRANGKVVIITGANSLLGIGRAAAHQFAQNGARAIYLCDFADEHLAAHKQDLDRRFPFVDIHVRKFDAADEASVRDVIKDALERYARLDVFFANAGILGPQTVFSNVDVEGFMQTMRVNALGPFLAAKYAAPAMQQTSTAKPVAGGSIIMTASVAGLRSNAGSTPYSASKAAVISLAQTLSFQLVGTGVRVNAVCPGLIETGMTSTVFEAARARGTQGKIGQLNPLRRAGHADEIARAVLFLGSDDASYVNGQAWAVDGGLSAGHPFVPGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJV5</accession>
    <name>A0ABR3ZJV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031">
        <property type="entry name" value="SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031:SF3">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="676" mass="72783" checksum="EBDC3C3C2E026E63" modified="2025-10-08" version="1">MASEETDWSKLTVVNLRAELKQRDLSTAGRKEELVQRLIDDDTNAGNEGDTGESNGAAEGGDDIDMKDEKEEEAPKEDEAAAETPAEPTKDALEPSTTTTQEPADPAPPPPSTVPMSEVILDEQKRKRRSVTPPPSLHNEAAGRKRQRVEGQEDNSELPSEVPSEAPSKSTSVAPAPQPNKDTDMAVDEDRPDPAPAPAGEVDMRDTADVADTGSISPALHPATTALYICHLMRPLRLSELEAHVASLAASPYGGDENRVDSVVVKSYLDPIKTHAFVDFANIAAAARVRAALHGQVWPDESNRRPLWVDFVPGDLVQTYIDREEAATASGSGANGGSRSSAKKWEVVYSEDDSDNGDGLVMTTLREVGSDTPIPGRILYDPSSPQNYQPAPVRDTSRMDTDDLPARRSPPPFDAPRGPKGSASARFTVDVTGDRFGAGGDIPPPPPREKRQRGGRGGDAWAPLDDDVRTTRAEPPLDYQLVIPDLVRRRQDSIQLHTAPRKGGNGKPDRSPSPGPGRNGQSHYTKTHNRYTFEQGDQLVDRGPEMFDGIRPPHREREKRQQRRNGGGGGGGGGNSGRLGGGGGGGGGGGGGGNGGSGGRRRRRNRRGGGGGRAYDDYRPGRDGRDDRDRGGNRGGDRGGDRKNRDDRRDRDRGRNDRGGRDEREGRLGGYNDNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK77</accession>
    <name>A0ABR3ZK77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOP1</name>
        <name evidence="10" type="ORF">Sste5346_002533</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="34061" checksum="0E141B12ACDCE562" modified="2025-10-08" version="1">MGFVPRGGVRGGGRGGFGGGDRGGSRGGFGGGRGGARGGFGGASRGGPGGRGGARGGARGRGGDRGRGGRGGGRGGAGGASGGRKVVVEPHRHKGVFVARGGKEDLLATGNFAPGISVYGEKRITVENTTKNEDGTPAGKVEYRIWNPFRSKLAAGILGGVDNLFIKPGSKVLYLGAASGTSVSHVSDLVGPTGMVYAVEFSHRSGRDLINMASKRPNIVPIVQDARHPLKYRFLVPMVDVVFSDVAQPDQARIVALNASMFLRQGGGLLLSIKASCIDSTAAPEAVFASEVQKLKESRFFPKEQLTLEPYERDHALVAAVYLQKEFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKR1</accession>
    <name>A0ABR3ZKR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Gpr1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="24823" checksum="450E7D9F6353A14D" modified="2025-10-08" version="1">MSPSTPSVSSKTGGADLEAQVTISPRDQPGLPFVPRNFANPAPLGLTAFATSIFMMSLMNLHPRGVAEPNIIISTMIFFGGLCQYISGIMEFVAGNTFGATVFSAFAGFNVAYALIFIPGTGILAAYADPTTGEPLPDLPQAIAMFVWAWFIVCVIFTVAATRASWVLLILLVFVDFTLLFIAISYMINSAALLTASSATGFISAFLAYYAGAAGLWGNGGTAINLPVGSLIPKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL94</accession>
    <name>A0ABR3ZL94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">srp72</name>
        <name evidence="11" type="ORF">Sste5346_002600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031545">
        <property type="entry name" value="SRP72_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17004">
        <property type="entry name" value="SRP_TPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="10">
        <location>
            <begin position="627"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="588"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="703"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="600"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="652"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="731" mass="76412" checksum="816ABB5A3793BAEA" modified="2025-10-08" version="1">MAAAVNALNSLLRGTSIDDHEEALKLANAAIANSKPGQTNPEQLTAQHAKVVALLKLDRFDDALRTVAAAGDALAARTVLERAYALYKTGDLDAAAELASSKAANRALKHVAAQVAYRAEQFDLAAGLYSGLGDDADSADDAAVGESTDVRINALAVSAQRAWQGRGSTTVSAGQDAALDAGRREDLESFEMAYNAGCTAVARGDVGKASILLRRAQQLCEGSDELSDEDKRAELLPILIQQAYTLTRLGRHEDAAALQKAIDANECEGSAKVVSSTNAVVLKNTNTSTNPYVVQRQIDAIPTPPTGSDRLFAHQARILCRNQYAIELQCYKFKGVLSRTAKQLKRQSGGEDSDKENEGASTATSPDTVDLGIFGAAAKAELQTGKEALRRILPLLEHRPDDVGLVLTAVQLQLQAHNAEAALSLLEAYFRRAEESSAASSKDARFAPGLVALAVAIYKLQGRHHAVRAELAKAVSHWQESSKTTSSALPASLLRAAGVELLHSQDPTDQAAAASAFEKLHAADPDDKIAAAGLVASLAAASSTGSSTPTQSARQQKLAASLTPVDQLVKGIDVNSLLQGGVATLATPAAPTKGKKRSADAATTETGADAAQPSAKKTKTGGAGGAASKLSRQARKLQAKAAEEGSTSTFDVNKKMDPERWLPVRDRSSYRPPKGKKGRGRRGEAALTQGGVVKEEETLALAGGAGSVRVEKAPQGPSGNAAAKKRKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLT2</accession>
    <name>A0ABR3ZLT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRE8</name>
        <name evidence="6" type="ORF">Sste5346_001809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="5">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="154"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="298" mass="31929" checksum="90E2C3DA786CBF03" modified="2025-10-08" version="1">MADRYSFSLTTFSPSGKLVQIEYALNAVNQGVTALGIKATNGIVLATEKKSSSPLADPSSLSKISLITPDIGMVYAGMGPDYRVLVDRARKVSHSGYKRIYNEYPPTRILVQDVARVMQEATQSGGVRPYGVSLLIAGWDEGILPEEELEREAAKAAAAAAGNKEEEEEADGLASGEQKKPTGKTGGILKGGPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYTEGLELEDAVHIALLTLKETIEGEMNGDTIEIGIIGPPADHLLGVEGVEGARGPRFRKLTPQEIEDYLTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM71</accession>
    <name>A0ABR3ZM71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">General control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GCN4</name>
        <name evidence="7" type="ORF">Sste5346_001927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="247" mass="26128" checksum="467849EAEC56C9C2" modified="2025-10-08" version="1">MHRTASSQSTSSSDLQGLSDFAAVNFDGASFSSPAMAASYDLTSSVSSSSASNLGTVSPNDLLLQDPFMSAPNSAALTSLTSPSDFNDSPYGDSYDVSPNFGGNDFEAGAHDTWFPLFAQDTTASVAAGPVAGGAITASPASRPVDEIDESETTPSRRKSSGHSRSPSTSQKHSASAGVNASRRREKPLPPIIVDDPSDIVAMKRARNTLAARKSRERKAMRVEELEEKIAKLEAERDHWKKMALGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZME5</accession>
    <name>A0ABR3ZME5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024146">
        <property type="entry name" value="Claspin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018564">
        <property type="entry name" value="Repl_chkpnt_MRC1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14396">
        <property type="entry name" value="CLASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14396:SF10">
        <property type="entry name" value="CLASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09444">
        <property type="entry name" value="MRC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication checkpoint mediator MRC1" evidence="5">
        <location>
            <begin position="1122"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="417"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="572"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="636"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="946"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1208"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1295"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1469"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1522"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="310"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="336"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="578"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="651"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="738"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1038"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1118"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1131"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1317"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1380"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1395"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1430"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1469"/>
            <end position="1491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1556" mass="167952" checksum="B5C138DACE9B0281" modified="2025-10-08" version="1">MAALSRTPSPAPGSGSDSDSVVATPMTPRTKLRELFATIDGGNNDGSSGSDNERESNEENKTPSRKAKKTNTSAKLSARKSPRPDAAAFVPSPTQTRPASRPPRAVSPLIGAGALGASSDEDSDVEVRPRGRFAARMQAAAAAADSTSTSSEPLADNPRERVKRMLQQAAGGADAEKDKAEDTNDAEDEEDAPVVARPRKRLTNLRTARRSASASPRQSQSLSATPSRSTREDSPPMFMTPSKQGEREDSPDMFMTPEKAGNDDTSASAAPGRNARFQALVARKQKEARAREEAEERKREARMAAMADNSDNDDDDDVAMGGLDEDDDILMRDAEGADDNPSDITDDEGGRQLTQNMAGARPERKASKKALEEMHRETQRMARNLQLTHEAKTRKKVTKASLFERFNFHPTGAAAAAAAPVAKEPTSSSRPTSPVSPNNNTDTEMRAVADTPPSSPPVPVVPDALFDKTKETAVATTTTLESADLPRLDKGKGNAVETTVVADEQPKTEVKRNIRLRMPMVQTNLVMIDSSDEGELEIVQTTKNKLDILFDNVPLKREQEPRSMFALRRLAQIGSPGKKPRARPAAKGKGAKNGAGAGELTLSELQQSLQERARRQAKLEREERLDMLRAKGVRIQTEEEREREMEEVDDIVARARQEAEELMQRERDEAKKGKKNGGEEDAVPDVLDWDESEDGEDYEPEEEEEEVEEREIELSGSEDEEAENEGDVEVLAGTLIDGEAESTDNDSGDDKDKDEAEDADDKADVLPTPTRPRPAKRRAALIISDDEDEGDDNHNDNNNTPAAAKPAFLAVEAKTPGPKNPFAKSPSGLSAANNNNNNNSDSPQVPTSVLRSATKTFIPGLPVAPGGPAGLGLTQIFAGTMSDDSQALVGGSPSQFMPTIGNFVDADYSQMAASGEKTNAAAILDSQPLATTVAMTQEDWIKRIKGEGSNHDSNNSDGGGTGPSQMVQFNFSQSQAHGLDSLLREPDVSQMSTLGPSQDNGPQEYTPLKVRFIENQPSTIETVVLDGNATQRTQPLTQSQSVVPASQQSPAEPRRPRGRLFRKTDVAKIVEEEEEADVEDEDVEDEQDDEDEAEPTQDQSIEAATAFAKMRQAALQKQFDRKKSKAKEMVEEQAEESEDEYAGLGGADGEMDSDNESLASVKDIIDDDQKVSRTDNAKLAAFYADRERENDEKQVEKLFRDVTTGMLRRKRGHGASGGAGDYDLSDSDDGGEARRRMKRRQFARMQKALFADERVSKVAENPRNMAFLRTIEDRGSDDEMDFIFDAAEVPASVPSVTATDSAAPAAPVDTTTSIPDSQPMASAAPAPVASEHQHPRRRRLSANPGKKPANIGEIRESLSSLLEDYNNDGSNLSIVADSEFGSDNEEEDKENVPEAAAAASAPSVVRRPGRNHNVQVVDRISLKRNNSNMSSASTSSTSSSSTASTTIAPGMGPTGFRVPALLRRATTNSLVSTSSSGSGAGSLTSNNTNSNKAADKDNGKIKKNASKMSGIHYFARENERRAALAESDKRRQAKKAKNAEGRVRAVGGLFGAGKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMU8</accession>
    <name>A0ABR3ZMU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="112"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="645"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="671"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="685" mass="76859" checksum="026018C212EC47AC" modified="2025-10-08" version="1">MSGYIQHPQVHSAVIGQIPVPHGPETGAETETYPMGPEGLYTEEQEREIFKYITHPDDSFNEAGTYWADLPLMQRIGFVNKVNNAEALSELKATWSLFKRDPLGPVAWYFRNAVLPGAGLGLEGYVLFSIGNLSPLFSAAWPQCWGSKATECSKNWIAAVTYLEVIGIMIGQVSVGIIGDWIGRRWGLIQDALIMFVGLLMLTASWGLTLQGWVICYAWSLFFYSYGVGGEYPMTATSSMESAVGAGKLSTRDDRLHRGRKVTMAFLMQGWGQLVNQGLLIVLLLVFHHGDGDPPYGLSTVQWTYRLSFAFPAVGTLWLVYYRTYKMPNASRQLQLVKKRNNVTGYDVNSLRTIFKHFGGRILATAGTWFCNDVFFYGNKLFQSQFINVIADNPTSVMVTWVWNICNCIVSLAGYYLACFLIDNKLYGRKMMMQVGFLMCFVFFVVPAFHYKYYSGLSGIHSFQAMYFLSSFFNQFGPNSVTFLVAGEVFPTPIRATAHGFSACIGKSGALLASVLYNYIDTQTKFYVVPWFGLAGMILTLVWLPDTTGLDLKEQERRWSYIKDGRESEYHGIAVHPTHLSLWERLWGVGKYYNPELDAKAKIQDLRADWEARESAKREAEVHGKDGDVVDDAGLTEDAHRFFLHTSPNSPYMQSQNGKPNGVLEDVLLPNSANEKTGEPSESSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNR7</accession>
    <name>A0ABR3ZNR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CHS2_2</name>
        <name evidence="12" type="ORF">Sste5346_001287</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF38">
        <property type="entry name" value="CHITIN SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="899"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="935"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="969"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1013"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1138"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1172"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="11">
        <location>
            <begin position="477"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="349"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1235" mass="136944" checksum="3E9AEE399798041B" modified="2025-10-08" version="1">MDPGTPTRPPDYYLGYTEHNDSHGAHDSLTGATTTHTHTTSTNPAAVRLLTSMDGSGMHDDDGLTPPSLRTSGARPLHHGNISAVPPQLPEIRPLGSSTSYVSSTATSSFTPPLSLSSKVAAAVSSLEQRERQQRQGQQGQVQEEQSSTAIKKTQASNTPHKSVKFAQDQCSSPLNGEILETASTSTPTPQRLRFAASQDPFQVSTSPGRPSIDPPMMMPPPPDSSYSPLRGLRGDIPRSASPTRPWTPSRRSYANSMSHAHSNSFSSAQAPEYSRVPPAPAQYEPADINGSPRPGTPASQYGGSPRRPLPPAPLFSAVGSNARTSTFADDATVSIALGDEEDLTEVSGISSAYTRQSRQPRGSNASYRYEAASSMDDDGDEDDVFRPRSEVSGGSRSRQTMYGNNFSQVTLNDPEAGDDDEDGGKDIGEMHAHKDGMEDDGDADSFVNGNKEKVEYYGPAPEGRQERRGVREPHMSKKAVQLINGKLVLECKIPTILFSFLPRRDEIEFTHMRYTAVTCDPDDFVDRGYKLRQNIGRTARETELFICVTMYNENAYDFTRTMHAVMKNIAHFCGRNKSRTWGEHGWQKIVVCIVSDGREKIHPRTLDALAAMGIYQHGIAKNFVNQKAVQAHVYEYTTQVSLDSDLKFKGAEKGIVPCQMIFCLKERNQRKLNSHRWFFNAFGRSLNPNVCILLDVGTRPGNNSLYHLWKAFDTDSNVAGACGEIKAMKGRFGGNLLNPLVASQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYHALQNDETGHGPLSQYFKGETLHGQHADVFTANMYLAEDRILCWELVAKRGERWVLKYVKGCTGETDVPDSVPEFISQRRRWLNGAFFAAVYSLVHFKQLWSTDHTIARKILLHIEFLYQLLQLLFTYFSLANFYLTFYFVVGGFADPTVDPFGHNIGNIIFTILRYTITLLISTQFILSLGNRPQGAKKLYLTSMILYGIIMVYTTFATIYIVVRQLRDSSTVLKIGNNVFTNLIVSTASTVGLYFFMSFLYLDPWHMFTSSAQYFTLLPSYICTLQVYAFCNTHDVTWGTKGDNVLKTDLGGAVGKGSTVELEMPSEQLDIDSGYDEALRNLRDRVEVPESPVSEAQMQEDYYKSVRTYMVVTWMIANGILAMAVSEAYGSSGIGNNFYLRFILWSVASLALFRAIGSTTFAVINAINVIIEGRVRLSLKVPEWFGSFGSKISEAGSSIVSSVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNZ6</accession>
    <name>A0ABR3ZNZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-mannosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40020">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40020:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045719820" description="Alpha-mannosyltransferase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19428" checksum="B7ECA6603F025297" modified="2025-10-08" version="1">MPPPHLHPRSRMTSSLFATTVFASFFVVVLPHVLPCPAPRVALADGQMVEVAADGTVLPQQQQRRRRRRRLQDEVMGPSSDAPAPPPVGATQVERDADGMARFAMETGKRTSDSESSASQLSSSPRRPNRECPVPKPGGIVGELLGFKSEQQQQQHQLQSQHQTQKQSLPHPTSLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPN1</accession>
    <name>A0ABR3ZPN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formin GTPase-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formin GTPase-binding" evidence="2">
        <location>
            <begin position="319"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="864"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="740"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="921" mass="100501" checksum="340D32534E37F3DA" modified="2025-10-08" version="1">MASVNGQSAPPAGGHHQRTKSSVLRSFMIHRRNNSQGDNLAAVALIPNQGVGGGPLEDISHNRQQQPQLVHAEKHPISRGNSGSSYTQSNLTNNSANSPTKKTKLGNTTTITTGNLPNTMNENDTDNASQPPPSPTKKDRGFAGLLSRPKSFKNLHKMAKDAAEAEAEEERGRGRSRGDDKKRSKSRLNFKDNRDKENKARSSPVADNSAATSAAPQVTPIYAQFCSASKGVGRDDLANKPLPSLDDAALGGTSSRQVPAIKPRPKSFHPVSASVGGSTPVTRPKLMTTFSSTRQTQHAGTSTPSSATPAAETPSPFDLPVDPNDIDAHLEALLDRRNIPEHQRYKMRNLANAIKMELIRQDWAEERSKRQQQSSDRPQSNDSTRSASGGSDQKAVANTPTPAPTNDGSAGKSTKSKHSRVKSMTFSKVTRGRSRDRGSNNDSTKRLKSPGAPLKKKTEGTLGRHLRSKSTESFMNMGNGTGTATSPDAVSSANPSNPITGFFAKAKGPQQNSPADFVTHLRTVQAPEKMEVGKLHKLRLLLRNETVAWIEDFIGQGGMEEVVGLLHRIMAVEWREEHEDALLHENLLCLKALCTTALALQYLHSNHASLLPALIHMIFDPEKKGPSEFTTRNIVTWVLFTYIQNAPIDERPARAQTVLGYLRDPERGDDEKPISFVMDMRKERPYRVWCKEVVSVTKEVFWIFLHHLNVVSLPAAAKDRKTPVSATGEDEFFSRNDPEATSAVSATTTSTPLPPKHTETASSYMLRHFPQERPPVPAAPYVGGVEWEATNYLASHLDLVNAILACTPTAAERNHLRGLMQMSGWERCMGSSLRLCKEKFYGAVHDGLRVWVAAAYEDGWDVRDVRYGPPPPPATPSSVADRGRSNSPNKRAPIIGGPKAAEPAPKLEIPKLDFILDGEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ38</accession>
    <name>A0ABR3ZQ38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="107"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="624" mass="66568" checksum="CC0EDCC80751969D" modified="2025-10-08" version="1">MPARKIQTGLVEPDERSPLLNFPQIVRSTATSSSSSLSKKGGAVIRVTESGSSDETETQGRNSRAPSFTESMSTDSSLLQDIEAEASSVQNAPKDGDESNFGTILRVVLVLLIGVVVSNADGSLVLATHPVIASEFNDLESSSWLFGGFILASAATQTIYGKLSDIYGRKNLILISYIIFAIGCGLVGIGQTMFQVILGRVISGAGGAGMTALVSILISDILPIRDVATWRAYINVAATTGRSLGGPVGGWLADVIGWRWSFIGQVPFMLLATVLCQIYLPSNARHYKGGKYVAPDNSVSAWDKLKRVDFLGSSLLALTLLAFLVPMEIGGSKVAWSSPIILTLFASSVVLFVLFIRIEKRAVEPVVPLGIFKVRDANLSIFIQMCQLSAQLGLMFTVPLYFKASAQVSNTEAGAHLFPAVAGNAVGGIISGLYIKKTGRYRNLIRLAALSASLSYTSLLFRWNGHTNWLESLYIIPSGFGAGIVQSAVFISLQAVVQPSHMAPAISILYLSSTCAMILGLACASSIMGVALKPALSSKLLELDLDPALTAEIYKNALSNIEYIATLTGAVKKAVIEAYVDSMWWSHVVSLGFSSLAFIASLVIGEKPLKKEPAPVRLLDDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ90</accession>
    <name>A0ABR3ZQ90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF12">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="622" mass="69454" checksum="7792B21EE25743BD" modified="2025-10-08" version="1">MASIDGDNIARIPLGNTTTTRTNNAAMPAPEYTVKEEPLGTARHLRIVGIGAGASGINMVRTLRLKLRDNYEHVVYEKNTDVGGTWFENRYPGCRCDIPSHNYQFSWRPNREWSNFFSPAEEIGAYLCRICEDEGMRGDVIKTEHEVLGARWDEGQGRWSLAVVNLRTGERFSDYADFLVNASGILNNWKWPEIEGLQGFEGDLVHSARWPAEFDYKDKAVAVIGNGSSGVQIVPAIQPDVKKLVHIVRTPTWIIPPRVQIFNMGPAADVMSNVELDDEENFTPEQIVRFQSDPAFYRSFVKTIEKETNNSFPILLKDSPMQEFAAEHVRQYMTAILGEDERLCKALIPDYSLGCRRMTPAPLYLQTLTQPNVQVVTEGVRRVLPQGLELASGKIVEVDAIVCATGFDVSFCPRFPLVGRNGNLQDIWRTSVPQAYMSCAVPGLPNYFTFLGPNAPIGHGSVFTLAEHIATYIAGVIHKCRTEGIKAIAPSQAAVDDYNEHIRAFMPRTAWSSSCRSWFKGTGDDKDGPVTALHPGSRIHFFHMLENFRGEDFEYVYDVDESHDGAGVSSRNRFRFLGNGFSTKELNDDADPTWYLDDIALTTTSPDGAASPKARTRIKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRI9</accession>
    <name>A0ABR3ZRI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aromatic/aminoadipate aminotransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARO8_1</name>
        <name evidence="8" type="ORF">Sste5346_000681</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163243" evidence="6">
        <location>
            <begin position="22"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="268"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="618" mass="67820" checksum="BF319DD3F7D77ECD" modified="2025-10-08" version="1">MSHRAVTTLLFRRCLSTPATALLTSSSARTSRKLSQRGFASLQQKSSGSWQTAAAGRPRCFSVTSTSRSSSSAAAATEVQYESEPADRQYSITIGDIEARRKRDGRLVAGTAAMADIDSFKTFPAWRQLPKARRWDHILSKESAAREPCVLKQAARHLKKPGLISLGGGLPSPEHFPILNMSMRVPTGQTEFTEAAAASEDGGATVSMGKYDASQALGATSGGSGPAEYDLSIALNYGQSKGSAQMLRWVTEHTELVCHPPYSDWSTCLTVGSTGALEQALRIFCDRERGDTMLTETYSFSTALETAAPLGIKVLGVEMDDQGMLPESLDDLLSGWDVKARGSPKPHLLYTVPSGQNPTGATQGAARRKAIYDVCSLHDVYILEDEPYYFIQMPPYQRDRPATSTPAPAQTSDEFLQSLIPTFVSFDVDGRVMRMDSFSKVLVPGSRMGWLTASEQIIERFVRHAEACNQGPSGFSQAALYEIVEKTWGHEGYLKWLAHIRESYTQRRNILLDACEDHLPAGIVSWTPPAAGMFHWMKVDHTKHPDHGKRSILELEEEIFDLCIEKGVLVARGSWFAAQPDQPQTGMYFRATFAAASASAMTEAICRFGEAVRESYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRJ6</accession>
    <name>A0ABR3ZRJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fimbrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fim1</name>
        <name evidence="7" type="ORF">Sste5346_000591</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21294">
        <property type="entry name" value="CH_FIMB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21297">
        <property type="entry name" value="CH_FIMB_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21300">
        <property type="entry name" value="CH_FIMB_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21303">
        <property type="entry name" value="CH_FIMB_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="51"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="145"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="294"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="419"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="544"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="655" mass="72680" checksum="A886D332D9F5423B" modified="2025-10-08" version="1">MNVLKLQRKFPQFQQNEIFELSNAFRNLDVDDKGYVDEATAIKATQASERQPYDVVRQALKEVDLDSSRRVELEDYVGLIANLRGNAADPKRISTGASPLPGPTSPKAGIVSQRTGGGGHASKGSVSGKIHVQGSNANTTHTINEDERTEFTRHINAVLAGDPDIGNRLPFATDTFEMFDECKDGLVLAKLINDSVPDTIDERVLNVAGRKTKTLNAFQMTENNNIVIESAKGIGCSVVNIGSGDIIEVREHLILGLIWQIIRRGLLGKIDIKLHPELYRLLEDGETLEQFLRLPPEQILLRWFNYHLKAANWPRTVSNFSSDVKDGENYTVLLAQIGHEYGCTRAPLQTRDTLQRAEEVLQNADKLGCRKFLSPTSLVAGNPKLNLAFVANLFNTHPALDPITEEEKAEVEDFDAEGEREARVFTLWLNSLDVQPAVQSFFDDLRDGTILLQAYDKVVAGSVNWRFVNKRPAHGGEVMRFKAVENTNYAIELGKQLGFSLVGIQGADITDGQKTLTLGLVWQLMRRDITVTLSALAQRLGKKEITDAEMVRWANEMSKKGGRNSAIRSFKDPAIGTGVFLLDVLNGMKSSYVDYDLVTSGRNDEEAYLNAKLSISIARKLGATIWLVPEDICQVRSRLVTTFIGSLMATYEKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRQ8</accession>
    <name>A0ABR3ZRQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alanine transaminase</fullName>
            <ecNumber evidence="8">2.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ALT1</name>
        <name evidence="8" type="ORF">Sste5346_000652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.2" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004021">
        <property type="term" value="F:L-alanine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="108"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="485" mass="53333" checksum="57EC3DFCEAB6331C" modified="2025-10-08" version="1">MSASSQRRLNHDNINPHVKAAHYAVRGELAVRSEEYRARLAKNDTSLPFNQIISANIGNPQQLDQKPITFFRQVLSLVENPLLLENEDVLINSLGYKTDVIARAKWLLEKVGSVGAYSASNGAPAIRQSIADFLERRDGYPASQADIYMSAGASSGVNTLLHVICAGPSSGVLVPIPQYPLYTASLSLLNAQCVPYYLDEAKNWATDMGALRSSLDDARKNDVDVRCIVVINPGNPTGASLSEEDVEAVIELAREERLVIIADEVYQTNVFVGKFHSFKGVLRRMQEQNPGKYDEIELASLHSVSKGMVGECGHRGGYFELVGFDPKVQAEIYKFVSIMLCAPVVGQCLVELMVNPPKPGEPSYELYDKEYNGIYNGLRERAIALHKAFDQMEGVECGEPQGSMYLFPTVKLSDNAVAAAAAEGRPADEFYCLKMLEATGVCVVAGSGFGQKPNTLHFRTTFLAPGTDWVSSIIKFHKEFMDTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS16</accession>
    <name>A0ABR3ZS16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF76">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="456"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="642"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="549"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="564"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="891" mass="99752" checksum="56C01D94130857F2" modified="2025-10-08" version="1">MDDTIEVRLPPSIQAAHDEREYNLDRVSPKTAEPRTMPDVSATTRRERDIWGTSPLDRSPHRSPATAYPNLENPEESTQKRKRSPSVEEASYRQETQRIRPHSHQQHQRGESDLPRILTATETAAAAIAAASAASRASKDNEPEPPRTSAEPRDPYDLSRSREYTARPYANEEREQQQQREQQQRDQQREQQQREQHHADMWFSRAPRDDRHAGPSNDNTAYHQHQRSGSVHSPAEDHSVNDSRQREKSVPHASASPQSEYGVNSPDDDERPPVYGAPFSPSNQKIGRPLQQTDPKRRKRNFSNRTKTGCLTCRKRKKKCDETKPECSNCVRGGFICAGYPPQKGHWGKPDPTKPTVQIESKDPTYVPPGAYGMPGPISGLQGGTFHQQRRESLPLYRGQALRIQPPQGRPIVTDDDRPTASTLPSALTSSDGHNKLSALSAFSAPANVFPTPVSAATTAPFPDRTPKEYQRVPPLHDLSRTTDPETPQLLTPLPQINIHRSGSPPYRQPSPQQNQLPPHQHQQPPPQSQPQHLHHRQLSQTEPPRQPQQREHEHDREHDHPPQHSSQNPHQPHHQSQQHLQSPQQFHPQHPHPAQHPSQQPLPDHRSQQPPPMQRHQPRHGTLHQEPLSIERQARFLHHRPYSPQPIAPRQPHQKEGGDEAEDSKEAEEARIASRRNVPFFSTVPGPRREREEMQAGRPFYQFDNELVDLRERCAAACWKFNNSTNPNIGVSQSERTRLFKEIIQPRGADLQAPMGPVGDQVVVDAPFHADYGYNITIGNAVHIGRNCHFSDAMQISIGNRVTIGPNVSFFTTAPSTDPMERDGVHSALQGRGITIADDVFIGGNVTILAGVHIGKGAVVGAGSVVTSSLPGFTVSHGSPATVKRGMAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS41</accession>
    <name>A0ABR3ZS41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine-rich transmembrane CYSTM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="6677" checksum="28DBC6230A2FEC02" modified="2025-10-08" version="1">MDAPTKTIDMAVPAKNAEPAVEQPTRVEPMSVEANMRGGDEAEEVCCGLCAAFACFECCKCCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS95</accession>
    <name>A0ABR3ZS95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051262">
        <property type="entry name" value="SMP-30/CGR1_Lactonase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572:SF5">
        <property type="entry name" value="BLR2277 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572">
        <property type="entry name" value="LIPOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="262" mass="28565" checksum="C92DF42AB1C044C7" modified="2025-10-08" version="1">MFYLDPPARLKEKAYTTVPEALSKTQPKGPCFDRSGRLFVVDIPYGRIFRIDKDKTWTVVAEYDGWPNGLKCTPQGRILVAGHRLGLVEVMPDTGEVTVLVIGYRGERFRGLNDLALGTDGWVYFTDQGQSGLQEVSGCVYRWHQTLARIERVLSDIPSPNGLVLANDASKLFVAVTRSNTIWRAPFVPDGGVSKVGVFLNLSGGGGPDGLAMDLEGGLVVAQPGLGVLRFDDSGVLTNFIQLPADNIYGGNAIFWLRYAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSC6</accession>
    <name>A0ABR3ZSC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7 8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pzh1</name>
        <name evidence="11" type="ORF">Sste5346_000222</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the PPP phosphatase family. PP-Z subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7 8"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011159">
        <property type="entry name" value="PPPtase_PPZ/Ppq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000909">
        <property type="entry name" value="PPPtase_PPZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="330"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="540" mass="58758" checksum="580EAB6D46F9FB59" modified="2025-10-08" version="1">MGNQGSKESGGASSKSSGPDGLQSYPSFSRSDTKDSTRSFKALRSKIPGSGKNDSPRSSAILSNTDASVERSDASSIKSGRANRSSLPPLARLNRSDSASSPTSVSSSIDSPQVKASSSFNELQPPPSPIQSASMKAGKHNVSAAQANGEVDHVSESPPAAAAPDPSTQAVQPGQSILVRRDSAASSVVAPTLAAATGSPGTEEAGVAMSEIKDMDLDDYIKRLLDAAYAGKVTKSVCLKNAEIVAICHRARETFLSQPTLLELDAPVKIVGDVHGQYTDLIRMFEMCGFPPSSNFLFLGDYVDRGKQSLETILLLLCYKLKFPENFFLLRGNHECANVTRVYGFYDECKRRCNVKIWKTFVDTFNTLPVAAIVAGKIFCVHGGLSPALDHMDDIRNIARPTDVPDYGLLNDLLWSDPADMEQEWDSNERGVSYCFNKKVIMDFLMKHDFDLVCRAHMVVEDGYEFFSDRVLVTVFSAPNYCGEFDNWGAVMSVSSELLCSFELLKPLDSNGLKNHIKKQRNSRKNFINSPPANVYPQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU55</accession>
    <name>A0ABR3ZU55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Resistance to lethality of mkk1p386 overexpression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RLM1</name>
        <name evidence="9" type="ORF">Sste5346_000243</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MEF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00265">
        <property type="entry name" value="MADS_MEF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033896">
        <property type="entry name" value="MEF2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="405"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="633"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="306"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="405"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="462"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="666"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="680" mass="73918" checksum="89D0C25A6DCF9031" modified="2025-10-08" version="1">MGRRKIEIKAIKDDRNRSVTFLKRKGGLFKKAHELSVLCSVDVAVIIFGSNKKLYEYSSNDMRDLIGRYTYHGGPNEHKGPNDFNGGGDDGSDDEVDGTPPPGLQNEAVESHMMPPHYPGQVPPQFAQFRHGTPSASPPIPNGVGFAQHAAATQAIQRGHTPQPPQNGSRPTSRNDMRRMPQNVQQQGPPQGPHQPNGYAFMPHPAIYNPQAQQNMQPNMNQPGPQYSNYAPPPTTHAPPPHIQQYVDERPASMPPSFPPQGMQGNSLPPPPQVQQRHSVSPPQGHSQQLPHPHAVQPPLPPPQHNPHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVKHEDSNASQPPQIQEPQPPTPVEPKADPEWHEVKRLPQRKQYSIFTPIDENRSILSQHLAAFQGNSVKAESSTSGQSTKNNDNSNSNNNNNNANRSQSVDSGNIASRSSVTSSPPNNKVADNASAQMPQPKSRVSISSIPETMFTPPSRQNSLRPGGPLRPRLRVEIPPDGSEDNSAATGTGGSASSPRNPNDAGPLGARRNGETHTGMVLPPPSPSASAILSAGASGPPNPFARPIPHQNNNNMHIDTPGSALPSRFLNNELLPSPSSFYPEWGFGRGSDSATLPSPLNFATPIVGTGPSFLRDDHLTSNKRKSPEASAGAPSSDPIDHNNEPKRVKVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU65</accession>
    <name>A0ABR3ZU65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL39</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL39</name>
        <name evidence="6" type="ORF">Sste5346_000122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_eL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="51" mass="6253" checksum="4E9DD09424D7A5D6" modified="2025-10-08" version="1">MPSHKSFRTKQKLAKAQKQNRPIPQWIRLRTGNTIRYNAKRRHWRKTRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFX2</accession>
    <name>A0ABR3YFX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000135">
        <property type="protein sequence ID" value="KAL1887214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="3">
        <location>
            <begin position="370"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="3">
        <location>
            <begin position="730"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1490" mass="161256" checksum="E2A92BC48E4572DE" modified="2025-10-08" version="1" fragment="single">MFYNAYNCVDGGPYKGWKALSSLLGILQAIVQFLSAMVLLGLYIHYRDDDSVGLPDDHAAMLLETSSRAMQIAVGVTGFVVLSVSFTFLIINQNEMFDPDQLTSAWFIVYGLVVSGAQLFNGQPYIGSAEQHAEIDAITEAARARRVAYAAQLRANQTAIDLTDAINKNNAVSQPTVAEAHRMVDAAISRWATTYEPYVNSPRRNSYESRHSEKNKNKYRSRQKPAEPHYKRSSSSVDSSDSADFAAAASAAALLAELEAAERARSGTLYRNYTFDAPGSPIQQSKVQFYAATSNMSASGGSGAAAATYWLEQIAAKEHGVAPFAGDANYKVFRNVKDYGAKGDGVTAGRFPSSFSATDTRANMLTTRLQDDTAAINKAITDGKRCGADCLSSTTKPALVYFPAGTYLVSSTIIGYYQTQLVGNPNSRPTIRASSKFVGKDGTTGVISSDSYINGGGGQKWYLETSNFYRQVRNLIIDIQDVTAVNASCFHWQVAQATSIENVACYMSSKVDTTQRGIFCENGSGGWMADLEFSNGQIGIYGGEQQFTAVSIQFVGCKTAVQFIWDWGWTWRSIYVSGANVAFQLFDAVGGTENPGSFLLQDSIIANCKTGVLTHPPKEGAKSGTTNIILDTVAFSGVPSPVADTTGKVLLGGLDPLQVTQPWSLGNTFMEGASSVNTGGQSVYGVGTILTYASRPERLIAQAGDIAWSSKWYKIQRKPQYGSVDINSVINVRDYGAKGDGSADDTAAFQVVFSHAYRSGGIVFIPHGVYILSDTVELDVGVMVVGECWSQLMAKGSGFSNLKVAKPLIRVGIPGGSVGLVEMSDLIITSKGLAPNLVGLEWNIHGPNSGTVPGIYDVHVRIGGAVNTDLQVAQCPQGKGISCRAGLMMIHITPYGGGYFQNVWAWVADHDINDDFNDRVNVLVARGWLIESTEPVWLYGTATEHAVMYQYSFSSASTVSAGMIQTESGYFQGSNGVRNPAPFTGSNAISFPGDPVLPDGGCANGTISCDEAWAVVMLNSTNINIDGAGLYSWFNSYDESCVDSWNCQESMIQIGGDSGNVSVRNLITIGGKRMVSGTPNDNFLEVAAGPNLNANGHPWWSILSSFEIQNTVKTTVYPDHRNFFGLGDSYASGIGADCGKITEDVPRGQDCSKCQGAYAYQLAHHFVPFNGDGGRGSSSLFKFYACAGAKTSGIRDPPAPGKVSQIRQMKDYGNFRDFGFATLSIGGNDVGFSRIVKNCIFWHTGECDNEWARSERRISSADLVANLTQTYQQILDTAEEPTFKLFVTGYARFFNEYTDWCNNKNLFPNIFLGPRTKLTREVRARSNKLTENLNTVIEKTTIAVTAAYRRRNSQKSVIFVDVDKVYDGERWCDGNDRSSWRDDTYFFNAFSKDLKRDGTTAVDTNDLTPHVIDIGGINVNTCMDAADDANDDDFMTRCAIAMFYAGNSTAQATLGTIYKADDGNGPTLQIIDSGKFTTSAIGQKAFHPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFZ1</accession>
    <name>A0ABR3YFZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-hydroxyisobutyrate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000133">
        <property type="protein sequence ID" value="KAL1887245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF81">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="3">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="4">
        <location>
            <begin position="168"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33955" checksum="89BFE3C8D67C2413" modified="2025-10-08" version="1">MAVAVRRSLDKKHMLYVFDVYMPSCERFKEQNSQFGPIEILTTPRDIATKADAVISMVPGPPEVKKIFLDEDTGMIGAPENHNRLFLECSTIDTETARSVAAKVHEAKRGTYIDAPVSGGVPAAENRTLSFIVGHAKREGMSVLDRRLNALILSMGDPNKVFWCGGIGLGLAAKISNNYISCSVLLLIAEAMAIGVKAGVDPKLLQEVIHNSTGQTFMGDNVCPVPGVVAHAPSSNDWKLGFKTQMFLKDLSLGINTARQLDLDPTMAEQAYRVFEKASQDPRCIDRDGSSVYLYITDEQTENGSTDKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH89</accession>
    <name>A0ABR3YH89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000123">
        <property type="protein sequence ID" value="KAL1887390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF137">
        <property type="entry name" value="PECTIN METHYL ESTERASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046820056" description="pectinesterase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="7">
        <location>
            <begin position="158"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="389" mass="42291" checksum="A1F07710324660BB" modified="2025-10-08" version="1">MRYTNAFLAAAAGFVLPATAVPTTNADYSLCQLPTSNVLEGCPHDTIVIGKDGHAAHFETIQSAIASLPNNTTPYTLLVLAGNYTEQLNVTRQTRDPLDQTKNLVTVYWSSANGADSGLTDNAYTSILTVAPNLNASLTGSGPTGFAVPPDTPFGCTDFRAYNIDFRNNFSEESAGPALAVSLSRSNSAFYHCGIYSYQDTVYVGKLGNAYFYGGEIAGQTDFLYGFGTAWIEQTRLVLRGCGGGLIAWKGTNTTFDNKYGCYVARSSILPSNDTIATTKLGRCSLGRPWNSLHRSVYIDTTMDAIVLPQGYTKWTSDPATDNYNNYTFMAEYGSSGPGWNYTARIEGNVTKVLDRAEVLPYRSAGAVFMRPDGSQPDYDWVDKRYYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI85</accession>
    <name>A0ABR3YI85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010423</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000144">
        <property type="protein sequence ID" value="KAL1887134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="272" mass="29046" checksum="0200C0A470F83696" modified="2025-10-08" version="1">MPVAIITGGGAGMGLAVATALVADGWRVALLDVNSSVGETAAASLSSPSCHFIRADATNYDELRAAFAETAARWGGNIDFVFANAGIAGKVDFYDDVDDIDDKEKEPQEPSLLVEEVCLRGVVFTSHLAMHYMRRNQPTPGDGTRGVIVSTASAASIYASPELPLYTAAKHGVLGLMRAMSVQLAPEGIRVNSILPGAIRTTLHEQTVWDQFPAGDFTPVNEVVQAVLALVRDPTATGRAIEISAGETFDRRQPDYCNDTMQRIMEGKSYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ56</accession>
    <name>A0ABR3YJ56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009678</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF156">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="455" mass="49935" checksum="A8BC9683564217E1" modified="2025-10-08" version="1">MALLSSLPSGWLAYAIAGILIAVIVRLLYRVRTDPLSHVPNAGLLAPISRLAWAFPHEYRGTITLDLPKLHDKLGPLVRIGPTEVSFYSLDAYDVIHKAGSKFEKDPRVYGGFVQDGHPALFSITDPGEHARRRRLMGQVYNRSKVPLLEELMLHHITHWTRCIARSPQAVDLPVSCRALEADIISDFSFGTTVGAIGAWANGGELAMVAKNDELASWMPVITNLPGLWEKLESLQTCLATITGYQPALWRGLGDFVEWSHNSFNTLTKSKGEDAAINPTSGFPTLAGTLTRSGLPALTALAEAKENMGPGTDTTSASLAHVLWALAHNASFQDELYRDLKRVGFSTDMTTLEGIPRMRACVKEGVRWAGAAAAMLPRVVPQGGVELHGMFLPEGTILTSSPIWYLRDATAFPNPDEFNPYRWMTPDATELRQDSLRDKYYIPFSKGANVCIGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ99</accession>
    <name>A0ABR3YJ99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nascent polypeptide-associated complex subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-NAC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EGD2</name>
        <name evidence="8" type="ORF">Sste5346_010170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAC-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000117">
        <property type="protein sequence ID" value="KAL1887509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="7">
        <location>
            <begin position="47"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="110"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="209" mass="22972" checksum="AEDD9F33BBDD5CAB" modified="2025-10-08" version="1">MANPRVEELPDDEPTNVKVEEQEEDSSDAESDIEVSAPSGSTTVIHSRNEKKARKLLEKQNLIRVEGITRVTLRRPKNVLFVINNPEVYRSPSSGCYIVFGEAKVEDLNASAQQAAAQQLAAGGHDHAGHDHDHDHDHDHDHDHGAEGGEGAKKEEEEDDDEEEVDATGIEDKDIELVQTQAGVSRKKAIKALKENDNDIVNSIMSLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJA6</accession>
    <name>A0ABR3YJA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53991" checksum="794FD71D5467950E" modified="2025-10-08" version="1">MTNVTNLIDRPSAPVTTDINLDDPAARSRRRVCNLTPWEVQRKRAIDRANQQHWRKKKRLYIADLEAQVARLTARLEEAEAKLKRYEQTEETEREVARPPTVTAVASPTSPTSPSASGPSPSRSSTSSSQPIVPTTQAQPQPQPGNNVQLDLFDPAPSSSLSLALPIFDSSLGDIEMNGDADADVDVEASVSHVVDKVLQPVMRQQQQQQQRRRQAPQTSPSPLATHVPYIPYYLGGRHHAQSQTYSLPDWMDLPLNLPVATELDKLVLITSQALVQRYSTREFSQPVFPSVEGLMSCIQTDARRSSVEADAQVGGVVDNSHPVLAAVACHVVWISPLKHLTSRLAFLYKLALFLRWCLCPSPATYNAMPHFLRPTLLQRRVPHPVWIDMIVWPEVRDRMIRAGDFGRFELFRSVTGQSMTVNWPYTDSGTFVELDLGVEGTRQALNPIFEAHIRNPDNYSVGREAALVFPVLNEYVREGRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJD3</accession>
    <name>A0ABR3YJD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="147"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="591" mass="66152" checksum="259CA3E3F574AE52" modified="2025-10-08" version="1">MDYPVVFHMVSDSKAFGYIDNHAEVDRIEALVTPFGPRLVRLYWLLVQPSFPLLCPARFMRDYAGASSYRAIHAPLLGAIYLQALTWWTYDSELSLWPLPDVGKLRRLTLDAIQMAFHRPRLASIQAMLVYLHCRPEAPLTADHTFARGLTSQMLAVAEAMGLHTDSSDWTIPTWERAERKRLAWALYMQDKWTALAYGRPSHIVDDNWDVQDLVSADFEEDEGVELGSVEEMLRRGRSDEEREKRHANGPGAARTNTSGASTSPAEGDVSVPSAPGPSGRIFFSLLLSLTKILSRVLSAFFTIRTSRDQDTARLLETATPFLTELAAWRTQLATALPVTPQRPRHLCPVGSIHFCYYGVVINLFRRLVRSTALAPLCSDPAVLSSIRQQAIQAAHEATHFVTSLRLDQLEAFWYFPSPYMFALVGSFHTLLLVTALSRTERDYWRETLSGFLWSLRIMSKASDPMRYAVNRLEGGVLRGLEHALVVNVDHPPSSLTTRGPNGSAGLVVDRHDLRGNGPQDTIVSRRQQELPSGATLPTAVDLEQLLLQLDSTAEFAYTDYSGFGLQSFDWLSMQMQNQDHDHGTGRGPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJK5</accession>
    <name>A0ABR3YJK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF1772-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the anthrone oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000091">
        <property type="protein sequence ID" value="KAL1888488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042">
        <property type="entry name" value="ANTHRONE OXYGENASE ENCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042:SF1">
        <property type="entry name" value="DUF1772-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="19572" checksum="4BC57D3A5566C04A" modified="2025-10-08" version="1">MSISINAPAVTSDAVRGAQAASIFISAAAAGGALGISTFLVPRILESPTGVMLRQWGRTFQASKIAFPGAATAAAAAFGFVYYKTANATSPTSLEVTASSLPLVAAGLCLAIVPYTFLVLRPTNKELLAKSALAEQDVKVTKADRAAGAGTVYTAQEEESAKQLVDRWATLSLGRPILLAAAAIVGLVAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK32</accession>
    <name>A0ABR3YK32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000095">
        <property type="protein sequence ID" value="KAL1888315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="271" mass="31286" checksum="AC791C68D9CE5D2A" modified="2025-10-08" version="1">MGKEETLKTREEEEAAEFDLATFFEDYGKEEQLDKDVNGIEDEDKESDVEVFDLSALFEEDLTMKRAQEAHPNQSSLAIEESVNEFSKEFSYEDAASIEVFDLSVFENALEKEASTIDFDLRRPSARETRAGHDVVLYYTAPTAPDNDKEYFDFERKTEIEICSARMSGARTRASVRRLRGLRAWTRAVTNRTNPRSKINRGTELPHGPKYRPSTISEPPLLEDTRDKLFENSSSNEEQWRIRFTGTTPELHQRYTPNSGRALKNMCRWSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK96</accession>
    <name>A0ABR3YK96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045716052" description="Beta-lactamase-related domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="108"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="466"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="65922" checksum="09CC2EE0666495F6" modified="2025-10-08" version="1">MKLLHTLVLTSSCLAPTVLADFATGSWKAPADLSSNFSLVPAAFANISNTLTEYILQDRNISFSKPEQLYGISNLTFSLGVFSLHDNAASEKLQYHVTGPEIALAGNGTTKVDAESIYRVASVTKVLTVLSGLLKLPAADWDRPLSDIFPVLASYQKQFPGGAFAAVNWTAVTPRNLAAQISGVPRDGFPSLNELEILGVLGSVDPSAMGLPPMNESDPLQNPPCVSYLLGNSSSGSAGGGSGLNLCPAQPYLESVANRPSTFNPWTSPGYANNGFSLLGLALANLTNTTYEKLVQGAVFDPLDMTSSSIDTPPKSQWNRSVIAGASDPSTYFDIEAGVFAASGSASTTLNDLARLGRGILNSTLLSAAETRRWLKPVSFTGRLQYAVGAPWEIHRYTLPNNKVVDLYTKSGDSGAYSAFFVLIPDYDLGFSLLSASSTLKLRFEILAAIADVVTYKLVPAIDAQAAYESTANFAGTYTLGNSSLTLVVNQTSTSKPVNGVIAGPGLVISNWTSNGTDVLHSQLVKYTGQLPYRLVPSVPEPSNNPSFRMLTPIDEPSAQQPISDSLFSGPGFVSADWVSVDALTYGGIGTTLFEFELDDNRKAKSVTLSAFRETLLKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLN8</accession>
    <name>A0ABR3YLN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Survival protein SurE-like phosphatase/nucleotidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="5'-NUCLEOTIDASE SURE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457:SF0">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046815022" description="Survival protein SurE-like phosphatase/nucleotidase domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="404" mass="41359" checksum="514097E04C9DAD02" modified="2025-10-08" version="1">MKTTSLVASLTLAVSVQGLNVLITNDDGFGTANIRAMYHAMTALGHNCYIVASSSDQSGQGSRLIFANNAKLTSDSEFGIVKSGAPSIGTDPNDDHIWYYNGSPATQVLVALDYVLPNHANFSVPDLVMAGPNYGPNIGPFLYGISGTLGATQTAIARGIPAIGYAGTYGTQTAYYDIQSSTKAGLQDPATIMGRLAANLAQAFIDKAHSSSNSSTGRILPLGYGVSVNFPLISSFTDDSCVNPPYIRARMTGDGAFTSKAVFNNDTGIFGSANFADDGTNMCINGDCSLPGEVEVLNSDCKSSVVLFTIDYDAPYGESSLVDPYTALLPDMVQLNNATNLVGGLGANASVAGGASTSTTGGNGAASTNSAAKSGGSRLSVLKNLSSSTLLALTAGVAVLATLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN70</accession>
    <name>A0ABR3YN70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018853">
        <property type="entry name" value="DUF2457"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48209">
        <property type="entry name" value="AGL056WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48209:SF2">
        <property type="entry name" value="FI24008P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10446">
        <property type="entry name" value="DUF2457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="775"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="820"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="876" mass="97139" checksum="00C70E2D2B3F0F44" modified="2025-10-08" version="1">MPNYTRHDTATSNVLAWTAHAANAVEEDAAADADEPPDQRQQSATTLHTFEKTTVYRPRERTESLLTRALQSQSEDEAAEHIPASGLYPRRRRSITSNTSMASTAGFTSDTGITTPPRTNSPSPRMVSVGFAPVNGEVRDAKAAAAPSMDTTPKPAANAASKDATKPETTAAAAPPRKRCISFACGAPKPSEVAKAKPASPPAPATKTPGPDDTPKAAYAQLAQPVQVTEPPKPVEQQVKRSCIRFACPAKPSTDTHKPQLSTLKLDAPENRVKAAARRPSPAPAPKSPTAIRRMLPRRDSANRSPRSVTRSSASRQASHSPIATRSKKYYNAEPSALNEESSRFHEFASDAVVEDDWIRREKATVQQRLTIRDTLAKELKISLLGKEAEEEAEEEDNDDENNDDDDDEDVDEDDDDDEDDDEDDEEEEDDDNDDENDTVEGENEYLPGERFAGYSSGVSDGYNTDNETGFASSDDEDDGLVLWAVNQPGRQRREHNFDNDHSTLHQGGSPIFRRLSVDEHSDSSGFIAGHAMRQERPKNRELVNTIRRTGTPELPDSTDFVCGTFDEDRPLEEAYQSHIAARKRGKTHVIPQDIDPSFPTSDPEDNSDDEPVNYKQRAQQHKQAHGSADERFWEIEDIQHDQIDNRTDARQKKRAVSPRRCRSPPPPKIRGRSPAPRRLFDRHSPTRRLKSPAPKAKAMPVPVAMPMPVPTIVASSHTRIVSPPASPVDALDNRGRPMFQTLAFKPGLTHTKSLPRPSAIFRHQKQELQLPAIQVQPQQQQQPAAKPNRRPKANSLAGAKQPKLRHVRGAIDIVKGLEQKRQRRRDKFQQKHCDRARKGQVPERRTQRGEGAERMREVGLLMAGKIPQGNYVLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNM8</accession>
    <name>A0ABR3YNM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008549</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="35"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="582" mass="64259" checksum="5D16DD89B334CFD7" modified="2025-10-08" version="1">MVLTAEQSQSAVGRLGAEKPHGIVGMIRNPYVFMTCAFAALGCLMYGYDQGVMSSVLVMESFQTRFPDLQGSTIQGWLVSALELGAWAGALFNGWLAEKISRKYSMMVAVIIFTVGTGLQCGAYKSAELFAGRVIGGFGIGMFSMVIPLYQAEIAPPELRGSLVSLQQQSITIGTAIAFWLDYGMHFVGGTSCNPEGIPAAQQYDNGVYNYTLAAHHHCLGQKDVSWRFPLALQLLPAWILFFGMFFLPFSPRWLMTKHRDDDCIAALSKLRRLDANDPVLRAEYLEIKASVLFDEESEAELRATGSFLGTWKTLFAPNMFRRVMIGCIIMICQQFTGINAVLYYAPQIFETFGFTDTTTDLLATGVTGIFQIVFTLPAVLFLDKFGRKSFLIVGAVGMMICHVIVAAIDGSFEDSWPTHRSAGWASIVFIWLFAVNFAYSWGPVAWVLTQELFPTSMRARGVSIVASTNWMFNFIIGLTTKDMLDSMKYGTYIFFAAFCAIGAAFVWWFVPETKDKTLEELDVYFGGDASGIAAADRERMARIHASLGIHGDVADLDAYQISDAKPQVEHNIDSVEAEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNT3</accession>
    <name>A0ABR3YNT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045045107" description="CBM-cenC domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20159" checksum="CAD169CEC54BBD79" modified="2025-10-08" version="1">MVQPKSIALALVAFFFGARASPCASCNPANIVQDGSFEAGSSVWTLDSGVTIETDAPDSDYSASGVNYVNIYIAQRSDYARYGLSQQLTGLVPNKPYTLQYTYELTDASGIYDGGVGIQTQLDGVQVDSVFMQSRDQQGIVQVRTVTITPTTANPLLYIDGYGSGNYYYGANVVIDDISLGQACNSGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP51</accession>
    <name>A0ABR3YP51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nuclear SAM-dependent mono-and asymmetric methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.319</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HMT1</name>
        <name evidence="6" type="ORF">Sste5346_008433</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="5">
        <location>
            <begin position="176"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="355" mass="40685" checksum="29608FFB1C75D057" modified="2025-10-08" version="1">MASMDQDKPAQVGEAMDVVKAEEKFKTMEHSEQHYFNSYNHHGIHEEMLKDEVRTRSYMNAIVQNKHIFKDKVVLDVGCGTAILSMFAVKAGAKHVIGVDMSTIIYKAREIVKVNGMSDKITLIQGKMEEVKLPFDHVDIIISEWMGYFLLYESMLDTVLYARDRYLVKDGLIFPDKATIFAAGIEDGEYKDEKIGFWDNVYGFDYSPLKETALSEPLVDTVELKAVVTDPANILTLDLYTCKTEDLAFSANFSLRCKRDDFVHALVAWFDIEFSACHKPVRFSTGPHTKYTHWKQTVFYLKDTLAVQEGEEIQCELHNRPNDKNKRDLDIDVKYKLETTDPTRTGEGSCTYKMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ12</accession>
    <name>A0ABR3YQ12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF170">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="92"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="540" mass="57395" checksum="E633F83CF527B77E" modified="2025-10-08" version="1">MSEIPPTDEARLIRPEVVTSLLDENNLVLPDDQINDFRVLLSALDEAAQHMLSFDDYQPTVDLEKYPRTDIHVPEDTCGGGWATKAVVTCTQPTSSLLAGRTIALKDNIALAGVRCTNGTTAVDWTPVVDATVAMRVLDAGATITGKASCENGCFGGVSDTSCTGPVENPWAAGYSTGGSSSGSGRLVAAGAVDMALGCDQGGSIRLPAANCGLVGHKPTWGLVPYTGIISLEATIDHVGPMTKNVADCALLMDVLAGADGMDDRVPMMVKPGTFDFVKEVNETLAKGKPLAGLKIGILAEGFMSSRMDLGVEKLVRSAAVKFAEYGASVLSVSIPLHTESAPTWMCALPIAGMRQGLLGDLTGRKQLFMTDRISMASPKLTQVAFDANGPGGQSIYLRGRFLEQKYGLELHARAMNLMRKLAEEYDKALETYDVLVMPTAPMLTQKTATAAEKKEKGMGPLALLNRNLGVTHNTAPFDFSGHPALSLPVGLASPVDDPDVKLPVGMQIVGRQYEDLVCMQVAAVWEKENDWKSLYAGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ53</accession>
    <name>A0ABR3YQ53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">threonine synthase</fullName>
            <ecNumber evidence="4">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_008391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01560">
        <property type="entry name" value="Thr-synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="11">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="104"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="555" mass="61183" checksum="6279A29F0701ABA2" modified="2025-10-08" version="1">MSGQSNGVAEKTHTASQRYLSTRGEDEDLSFEEVVLQGLGSDGGLFIPQEIPKAADWQSWAGLSFQELAFRIMSLYVSPSEIPPADLRGIIDRSYATFRTDDVTPLVHMKDNLYLLELFHGPTFAFKDVALQFLGNLFEYFLVRKNEGKTGRDRHHLTVVGATSGDTGSAAIYGLRGKKDVSVFILHPKGRVSPIQEAQMTTVLDKNVHNLAVTGTFDDCQDIVKALFADPATNQALSLGAVNSINFARILAQITYYFYSYFKLTQQAEGFKVGDKVRFVVPTGNFGDVLAGYFAHRMGLPVDKLVIATNENDILDRFWKTGRYEKHALSHREQQAQEANANGAGGLAVDGAKAHEDGVKETLSPAMDILVSSNFERLLWYLAYEFAAVAGMDDAWNKKQAGQEVATWLKDLKTKGGFGPVYKDVLETARRTFESERVSDAQTIDTIKNTYGNNATQYILDPHTAVGFTAAERSIGRTSPNVPHVALSTAHPAKFAGAVVMALKDEGGFDFEKQVRPTEFIGLEEKERRVSEVANDWKAVGALVQKQVDEELSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQC9</accession>
    <name>A0ABR3YQC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="50772" checksum="C4CF7A7C984AFE96" modified="2025-10-08" version="1">MQAAPPPGYGAPGQTGYFTTQSLGGFYAPISNNPPFGPAAQPQPQLFGTPGSAGQLFNGWPGSREEQEKMQQQQAEEVKKQEAQQRGNNCDGDNSQSRASSHRNDNNRGRRDGSHKSKTTHTKGRSTPWEEVVERLGDVTIKDEGDEDDDTASYDHCENSDGSNSPTSSARGSNSPTGSNSDGSDNGNQEVIIQTGGSARVIVHLNHFDRPPSTTTFLVSARRMLSLARGWPRVCHQGMNDFEVTANDGAAVLGMYWLLQVLHMSVEEQQFYQGHDATTSSSPDFKVHRLRPGMAPATTPRQVPPTIPSELPARVLAYATMYANHIGVLDNAQGEKQQQMLGNGPGALGSPASISVPADRFRSRAETWMRAVTTNPRCRRTLDSALVAPADWPFVLYTARVLGDRQLFTIVLRTLLDRWWLNERGIFCDVDGPARIDRLPDAIREVVLRDLSELSFPLPPMSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR77</accession>
    <name>A0ABR3YR77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carotenoid cleavage dioxygenase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="669" mass="72495" checksum="62961C932A153456" modified="2025-10-08" version="1">MGSVPEPFPAEAAVLPAPPGYRTVDDEKADYTQALKRVNGQSFKDWPNEAGFDGLREERGPIEIPVTGTIPAYAAGSLYRTGPGVMKVEGTPKGTHYISHWFDGLAHTHRFEIVAEPKDQPNAEAGGEAKNKITVFYSSRRQSEARMRLIQEQGAAKLFSFAQRADPCIGLLGKFMSTFKAAALGRSSTRHKDSENVNVVVHLNVPGVKGTPPVGTAATKADRRSMAVFPNTATSTADDKKISFTPAPQTSSGHRAKLPDSVWITTDATLMRRVDPATLEPIGVASQDTLHPDLKGPMSSSHAQRDPVTGDFYNFNLDLGATPTYRVFRVSQATGKTDILATIRCRNGPAPAGSVSPTIGGGSSGRTPHISNAKPAYIHSFFLTARYVVLCIPCTHVAQNGLKMLWDRNVLDGLEQFNPANKTRWIVVDRQIPGRGVVGEFDSPASFFFHSVNAYEEEEDDKGSIVCDIIDYPTSDVIHALYYDVLLNRNDAATDFYNDPVRVANINPCLSRYRLTLPSSSSSSPSRSSSPPSATTPAVRDWMIAGPHAGELPSINPRYATRRHRFVYSVANQGRSTLADGLVKTDTETRAALLWDAPHGHTPGEAIFIENPDSKEDDEDDGVLLSVVLDGTAGKSYLLCLDARTMTETGRAEVGFAIGFGFHGVHARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRE5</accession>
    <name>A0ABR3YRE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ubc1</name>
        <name evidence="10" type="ORF">Sste5346_007931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015368">
        <property type="entry name" value="UBA_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09288">
        <property type="entry name" value="UBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="235" mass="26162" checksum="8FDEE1D4B52875AE" modified="2025-10-08" version="1">MPPSRDHRVARELMDIEKDKDNSGVHAVPFDGNSLSHLKGSFPGPPDTPYATGTYTVDITIPEQYPFKAPTIKFETKVWHPNISSQTGYICLDVLGKNWSPVNTIKTALLSLRMLLEAPNASDPQDAQVAQMLLNDPERFKLVAHDWAVRYAGATRSMARPSEQNIRSPTTGPIDPTRYMGYNKDLVDRFADMGFSVDAVVNAFQNLGIERRDGRDYTMDAALIGDVTAYLFNDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS70</accession>
    <name>A0ABR3YS70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF445">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1330" mass="147189" checksum="4DF0971D12B18DE1" modified="2025-10-08" version="1">MSSSRTCKYGQRCKFSHDSNGSSTNTKNTKDNIPKRSEHDGKVAQFKRRVNQGGRADRFSTGNSAEGIFKLGLEILDNAQDAGLKQEVISALASEEGLACIRHIAASRIPLAMVGSIAAKFELWETEVCPLLRLVVHNTVVNSTLLEEKVATIHSFLIGVGASRLAAWFDLAVELAESTQESSTVSRIGLAELSLQVLSILLDCGTSHIVNDSFGRYAETLSAAIADIESSRPEDDFCKLQAAQYANFIGRRLKIGQNIPGIASTSAAAPVQLSIFQLQRDLPGHLSAEGPRHDNDHADIGKISILPTPSEIHSTRSEYLPTADPSTWHHPGIRGRLDREFRLLREDTVGQLRDVVRTELEYLQQSADHGSAQARPSRVTKDSIQYCIYDNAIIMDVGFDRHIGVEFLVRFRQPAAGQVLGKTKKDIAKSKNQRRDWWTIQAKKRLQPGSLVCTIDALGCVNFFTVADSTMRTGKDEDIKQSRKYKKDATQNNANEAEAEVKYTLADDPKHAYVRLGFSGIESKTQLEQALSWYFRCRINFKADADARDGSQLRTIVEFPGVLLASFLYTLQALQASTKKLNIPFSAILAPEDSEDGGGHGQYMAIPPPQYAQKPGFVFNMSCLTTDQDRLDHSVDRPVTFQEVCDRTKFDTTQSVAILEALSRSMALVQGPPGTGKTFAGVGILEVLLDNQKTADLGPIVIVCYTNHALDQLLEHIIDAVKDVNILRMGGQSKSEKLKNLNLRDAAVDMDRTRAEKRMLWEAGERLTEATQQLERLFEKLARSTNVSAVVNQLLIFHRKAYKELFKINGPQYDDNNDYGYSDDDDNKYDEDGFTTVIHGKPQDIIRQWLRSGEVGSGSPTAGNALGGKLFALTRDERNAAYRQWQTESFTYVQDDVEIRYDEYVAAKKTFDKARKEVDLRCLKMANIVGMTTTGLAKNHDLLRHLNSKVLLCEEAGEVLEAHMLTSLLPSMQHAILIGDHLQLRPQVQNYDFSVESRRGAQFAFDTSLFERLVSPQTGEAKIPFSKLSTQRRMHPSISALIRAPLYPSLEDGPNVHLYPEVTGMARRLFWLDHQHLEDGAISGKNGADLSGTSKTNTFEVEMTAALVSHLFKQGSYSGGDIAVLTPYLGQMMLLRQRLSGMFELSFNDRDAVDLEIADAIGFGADPTTSNIATAPADKHTVPAKTTLLNSVRVATVDNFQGEEAKVIVISLVRSNSNRQCGFLRTSNRINVLLSRAKHGMYIIGNGDTCAGIPMWKDVMTTLQAGDNMGPELTLQCPRHPEREFLALHQMVAVCSRVTRDLLVATRAPADATPTLFTQPSSAFSGALVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSA2</accession>
    <name>A0ABR3YSA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PMT1</name>
        <name evidence="18" type="ORF">Sste5346_008011</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23283">
        <property type="entry name" value="beta-trefoil_MIR_PMT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="623"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="665"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="727"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="344"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="424"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="493"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="822"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="914"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="822"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="842"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="872"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="965"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="993"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1890870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1009" mass="112526" checksum="AF71C8B5DDDC045A" modified="2025-10-08" version="1">MGRSSAARSPSARPPSRRATPPPSGNGGKSKSKKESAAARRPDDYSSDGVKDNDVFLLPGTDFQILIGVTVLAAIVRLFRIYQPTSVVFDEVHFGGFASKYIKGRFFMDVHPPLAKMLIALTGFLAGFDGEFDFKEIGKDYIEPGVPYVAMRLFPAICGILLVPIMYLTLKAANCRTSTALMGAGLIIFENGLLTQARLILLDSPLIAATAFTALAFTAFSNQHEQGPSKAFTPSWWFWLFTTGLGLGITVSIKWVGLFTIAWVGSLTLIQLWVLLGDTKTVTLRIFAKHFVARIFCLIIVPATFYMAMFGIHFLCLVNPGDGDGFMSSEFQATLNSKGMQDVPVDVLFGSSVTIRHVNTQGGYLHSHPLMYPTGSKQQQITLYPHKDHNNVWLLENQTQPLDSAGEPINGTDAWNKLNDNGELPFIHDGAVLRLFHPSTSRRLHSHDVRPPVTEAEWQNEVSAYGYEGFDGDANDYFRVEIVKKKSDGAVAKERLRTIESKFRLVHVMTGCVLFSHKVKLPDWASEQQEVTCARGGSEPNSLWYIEANEHALLGAEAEKVNYRRPGFFGKFLELQEVMWKTNAGLVESHAYDSRPSAWPILRRGINFWGKQHRQIYLIGNPFVWWTSTAAIAIYVLFKGIAILRWQRSCGDYSNATFKRFDYEIGTSVLGWAFHYFPFYLMERQLFLHHYFPALIFAIMAFCQIYDFATARFNVFRIKNNPLIGKAGALTILAISAVIFTLFAPLAYGNTWTKAECKRVQLFSTWDWDCNTFLDSYPEYEQFNQPSIAAVPTTPGAAPVVEQQAPVADIPIAGGEHGQIPVEQAQQQQQQAEQPKEEKPQEVQQEQQQSVAEPEPLHTEPPAPPIAVVEDEAQRVLSREERVEYRDQDGNILDPEQVESLRGKVEFKTRYETRTRLVDEAGNEIAEEAAPVAPPHPDVEGVDQSTKQNLVADDALPKSADPSVEGEREKEQSRAKPASENSEATQRRESEEAPAAAEPEAEAAPASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSN1</accession>
    <name>A0ABR3YSN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">U6 snRNP-associated protein Lsm7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lsm7</name>
        <name evidence="11" type="ORF">Sste5346_008006</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="98"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="51"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="219" mass="22484" checksum="9F80D8AE13965A2A" modified="2025-10-08" version="1">MSTPFRGRYSPASRGGGGNNSGGGGRGGNGEYRGRGGGAGGGGRGQYPRGGNRGGDRGGGFQRGGGGRGGGEGGRGGGFSRGGYGGHNSGDREAPKKENILDLGQYMDREIYVKFNGGREVSGTLKGFDPLLNMVLDDAQEKMRNAEGEVKSRSLGLAVIRGTHITTLHPVDGSESIANPYLAVAEAAEGDDAPEEGQASNKITPAYQYTPKADEEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT86</accession>
    <name>A0ABR3YT86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007777</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF5">
        <property type="entry name" value="NADH:FLAVIN OXIDOREDUCTASE_NADH OXIDASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="21"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="370" mass="40964" checksum="E17706C7677B7743" modified="2025-10-08" version="1">MSASYVSPLAQSITLPLSGKVIPNRLYRTPLSEYASTHDDKNIELCGKPLPRYAELYQDVADGGAGLICTGNIPIHREHLENYSNAVLDMNNPWDAVAAFKPAVQAAKSRGAVFLGQLQFPGRQVPKFLNKHPKSSSDTQLRPCLDKTYGEPSPLTKAEIQDLMDRYVWAASVLAEAGADGIILHASHGYIINQFLSPLINKRTDEYGGSLENRARFVLDIVRAIQAKLPSDKFVIGAKLNCHDFIEGGTSFAEMCVVIKWLEEAGVDFFDISGGTYESPAWRGNIMTELGTRPSQRLRGSYFIEWAQEMKKVLSRAVIGTTGGWRDGFRMSEAVERGDIDMCGLGRPLREDPHFVKKVLRGETRISSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTF8</accession>
    <name>A0ABR3YTF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthesis regulation, Congo red resistance, RCR protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187:SF1">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="18539" checksum="E9981CDC046CABFE" modified="2025-10-08" version="1">MAPAHEVAAALEARAYCPSGYYYSNGYCYRNSNWYGWGRWVLVGVIIFIFLLFLLLMSRRVRRQRRTGATPAYGTSWMGWGQQPQYNNQQNYAAPPPQYSQQPPTEPQYTGGTYNSNQGYYGQNTGTYNNDVPVQQPQNTYYPPREVNNDYAPPEGPPPAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTL8</accession>
    <name>A0ABR3YTL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053144">
        <property type="entry name" value="Acetyltransferase_Butenolide"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43233">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43233:SF1">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="25039" checksum="70DFFE7C9C0D8824" modified="2025-10-08" version="1">MATPTASPPLTWRTTVAAPTPADNITTLHQEYFLCSSDPALIDLDALHDAMSSDLLWWCKPLSRPQLVAMVNNSVCLAVYRTEAPESTTPGPMVGFARLITDRVTFAYLTDVYILPAYQRRGLGAWMMRCLRELCQGSGPDGERNSIPLTEGWQDLRSLWLVASTESAARMYMGALGAEEAARYRAQPGVPGSGMLLVEMPGPANGIRQHASRNAALAAKQAEEAAEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTN6</accession>
    <name>A0ABR3YTN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="50109" checksum="22F8320020F337D1" modified="2025-10-08" version="1">MPNQRSILSFFSSSASTELPKPQSQQPQVQPKSAAFGQPSSQSQSQSQSKVPPPPPPPPSFNRFVPPPSARNGSKGYTPPPGMSANNSNSNANGARHGGSADPVLDLAPITSAYGRSIFQAAGAIELEDGSISFPSSASNKIVFPRDIHMPDLVSINGILLPVRYSDSFYKGVTDPTRMASLFNRIILGDDGKTVVGGLVCRLEPTPFAGDSAPGASAGLAVYIQSLALLSPYRGRGLMAAALDSIIATVQALNQKAVVPGGPLATTGSVLSLFAHVWTEHDDALNWYTSRQFVRQDDAPIEDYYFALRPATAWIVRRDVSADIDPSVTQLVLEATQQAKKEQQQQQQSLKAAASNITPPPPPPAANGRSQSYQNSRPETEWNDLPADMMATPGLSANASTAASSRNVSRKVSQINLGDGTSSNKENDDSPPPQSGPATLLAPPTANGSQASSRSSSSMGKKKRERAYPAAMFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA7</accession>
    <name>A0ABR3YWA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006962</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF33">
        <property type="entry name" value="VITAMIN H TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="53"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="541" mass="59895" checksum="584A4DA72B878806" modified="2025-10-08" version="1">MSQPDSDGPGPDKNGVIFTSQADEGVAAEAAPEIVEYDLKRVEQMYRKLDWRIIPPFWVLYFLCSAIRSNIGIAQTMNSSQGHDLMQQLNLSSKDVSTALALFYVSYVIFDFPSNLIMTRLSPRVWMARIVFAVGVIGVCFTAVKAAWSLKLLRFLLGVVIAGMWPGMAYYLTLFYPPSRLAKRIGYYFTAAQLSASVVGLVSAGFQKMDGIGGLVGFQWMFLVYGLLAVVLGVVLLWWLPDRPLPPGTSRPAPHRLLAWVPRSPEALKGEDALVHYSEMRRVYRPRPWTVRDLLYVLIDWRLWPLMLMYFGVVGVGIGTQLYGSVIISAINPNFSSIVDSLLFAPIWMMDLIAILLVTPISDRFHRYRAVFFSAAVCIQIVGLLLVSFAPTSNPWARYGGMLMLGFGLGPTVPICMTWTGEIFQHRHGEVGVAAASALVSGLGNLGSITTTYALYTGWPADASPKNPHQFRNSNLVMIAILVVSIASSFINVVLLRFFGNKRHTATKAADDSHDDEIMDGAARRETEQRGFKHILPVGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWU6</accession>
    <name>A0ABR3YWU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="228" mass="25316" checksum="F39E236E508D4B2E" modified="2025-10-08" version="1">MLKQTFEEQCRGAISLVPVYFSIISGQVRTQSDAPLQTILGHVLHQLAGIHLDAKKSLDLSVIATSESEASILRTIYDADTLPLVLAGRDAITDTDTHVVELLDPQQKARLLVEGIAGAVAIVKMLTTHSYGTVTLSHLQHELHRFSSSARPQHIRDAVEHSRLFGDCLMMSQILDLIMDAAHDHHSQRTRRVATFDDYSADVFCSERERAAANNMGMPWGLEFMMLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWV0</accession>
    <name>A0ABR3YWV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CDC6</name>
        <name evidence="5" type="ORF">Sste5346_006811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="3">
        <location>
            <begin position="191"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6/ORC1-like ATPase lid" evidence="4">
        <location>
            <begin position="400"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="694"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="765" mass="80918" checksum="C01DF6168E3BEABA" modified="2025-10-08" version="1">MAASSLGKRSRALEVEDTDVSLPLKRTRRSTRSFVINDENQDPNAVTFEDALAADADATPKARRAISTNSTLVSPTKASPTKRSVSVAGVPLTPSTPRYRDGLTTTSASRSTSATTPATPVTPSTPRHRVMSAGRLSRRTTPHGMLSARGNGLGGDATPTTPRTPSGSVQTVYHVARQLFARSSGAAAGSLIGREDERSRLRTFLNANCGSDAAESKSDCGCLYVSGPPGTGKSAMVNEMTEQVCTEQSGSVRKAYINCMSIRSSNDLYSTLLRLLVLGSGNEDDNNTNEEQAAEAMGVDLNETDAMSALQAMFLPKASKKATAAKAASTPTTYLVVLDEIDHILTLDLDSLYRVMEWSMLRTSRLVLVGIANALDLTDRFLPRLKSRNLQPELLPFLPYTAPQIKNIITTRLKSVLQTTTLPSVPESSAPAPTSANFLPFFHPAAIELCSRKVASQTGDLRKAFEILRKALDLVESEAREKYLNDARDVCNASSANTLTTPTKKQPLAENINLASSPPASASSTLTVPKRSSWASWAAQNLTIETAPRVSIGHLNKVTAAAFGNGAQQRLKGLNLQQKAALCALMAFEKWNREAYATAQASAQTHSSLQSPNGVKKLVKAPTPGRLQVPAAGAGATAAPTIKKLYATYNLMCKRDAVLHPLSSSEFREVVGSLETLSLVTAVDGRTGSFAVLQSAPGSGSGRRGRRPGGAVSNNMMGGGSSGVTGVAGDEKRVASCVGEKELRQALDGAGADILQSILSGEALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXB8</accession>
    <name>A0ABR3YXB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="95"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="594" mass="62216" checksum="E73EEEC42F45D7E1" modified="2025-10-08" version="1">MSGDSTRVPTPAGTLTDQENNITNNHLNVNKEDQVGGETTDYDEKKDAAGDATSIDIEKTEANAAAAPAAGVNADGVAVDENGDAYPTGSKLIFIVVALVLTTLLIAMDMTIVATEIPKITDEFHGLDKVSWYGAAYFMCVGGSQSTWGKMFKYFPLKTTYLVALVLFEAGSALCGASPNATALIVGRAIAGLSASGLVSGAYIIIGFSAPPSTRPLLTSITGAAYGIASVIAPLIGGAFADHVTWRWAFYINLPIGAVSGLLFLIFFKTPNASRPKSATLSEKVWHTDPLGAALLMGAIICFILGLQWGGQTKEWSSGSVIGVLVAFGVILIIFAGWQIFQGERAMMTPRLLRQRSVWVSSLFSFNFAGGYFLIVYFLPVYFQSIDGVSPTASGVRNLPIIIAVTIATISSGVLMAKTGRVAAMMTIGGVLATIASGLLYTLKVGSNSGHWIGFQVLAGLGYGFSFQLPIIYAQSETTAEDMAATTAIVLCFQTVGGAFYDSAAQSAFVNTIIRKLAIYAPDLNPAVVINTGNTQLRTVFSGAELSGVLASYSRGIQIAFSLSIVGAGTATLIGMASSWRRIGHNPDAMGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY17</accession>
    <name>A0ABR3YY17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006823</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="123"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="123"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="229"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="418"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="64713" checksum="591E54D5C3BCC8DF" modified="2025-10-08" version="1">MSQRLEDELEELQLSQYYEAFVDQGFDTWETILDITESDLDALGVKLGHRRKLQRRIANYRGIAPDVALASPTRTSADDSTRPEPTSKQEAPSTFNLDSRGAVPGVLAKRKYRRHPKPDENAPERPPSAYVLFLNKTREELKGQNLTFTEIAKHVGENWQGLTAAEREPFETQAQLAKDKYNQDLSEYKKTEDYKQYMVYLQEFKAKHSGNQAQEKDAFKRIRLADFSTSSTPTIGTSSASPPAANHRDNDRRSKRKGEGMNGLGSRSGSEGPHDSDNHHISRKRRFGSTASGSDYTASPTPGLMHSPTTLNHQPVNSKHNDPAHSYRSPPSRPTSLSPHVHTASALPPNHGQSTAIRRSDSGGSAQMSLPSLSHMFHDDRRPHSPTANGPMSGSKPDAGSNNNATPGTASPGLPPHSNGMATSSSSASNASNASNASNASNGSATSYSTASSNGSGSYPRTPLDGSMPIHALLSGTSKPLSPTSPHSSSASPHSASIPPHPQPYPHNGMQHPPQHSPHYPPQYPQHQHAHSHHGPPPHDPPPYHHTASPKHSPPPAASWNYPHGQSPADHPPMYKDHGVSNMIRQPAGAPYQYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY40</accession>
    <name>A0ABR3YY40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex, subunit CDC26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018860">
        <property type="entry name" value="APC_suCDC26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10471">
        <property type="entry name" value="ANAPC_CDC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="44144" checksum="C8B6E992321C1223" modified="2025-10-08" version="1">MLRRPPTVLGVTAEDVAAYEDRIKKQQELQQQDRQRRQQQQIQILHQQQQIQQQQQRQGARYTAQQQQQQHPMGPGGLYEDAQPGAQSGNMSLPPFSSSPSPPPMDSEAYHYQRQRHHMSAAAMSSAAASRAAWRWTQQEGQRHHEQGPFPGGFNEEEEDDEEEDDDDLARGHPGVAGLERDEEDEGEDDLGGGVEGEDDALNTMANELLVDDSDDGGQMDIEYQQPPAAPSRARPRGAPSATGAPRRGQPSGGGVTGPAGRRTAPPPVRTPQQQVPSAAQMMTPPAIGGGPRGGDQSGPPPIHHPSSHPFPSAGGSGSGSGNPPRQANPSTTATQHLVHQNHPTYHPGSSAPMGPPPVMRHPHADGRGGASRRTQQQQQAAANTTPSEGRSTRSRDERIGVGGGAAGRVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYZ5</accession>
    <name>A0ABR3YYZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006606</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF19">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="36"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="366"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="463"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="482"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="515"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="548"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="564"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="605" mass="65603" checksum="02829C1093599B3C" modified="2025-10-08" version="1">MGLYSDPPPMLAFAEVKPTLLVCWWITVFCLTIILLRIAGRYIRSERLFIEDRVVSLAIIPLFLRMGCVHAILIFGTNNVALDSFEHTEENLHRRAVGSGLILASRVFHAATLWIFKIAILEFFKRISDALSERFSQVLLIAIRCILVATFIAVVISDLTECQPFAHYWQVTPDPGGHCRQGFAQLLTMSVCNVFTDLLLVFFPIPIIFFSHQSVKRKVQLILLFSLSLGVVGVTIYRVTRVIQEHGNQQLRSLLASVELLFATAAANSLVLGSFVRDRGVKKNKFRAGSVVDSMERSSVIRSRRPTANRHWGSDEDLVRDLGLGVQPELRDAPDSFIGDDVMFNGSAGGRTVRPAPILKVDGSVVDPLHQDNTGEGSSHSGGDSGIGHGHGHGMVGDFSAWQFPENRRRSAATNSAQSAQSGLSVLSGHSDDDTLLARDPLSPASRNNSTSTPRKVSFFDAGNLLGGNNNVGGDESEPDTPRTSTAGGLRSPSSITGMRSSTDSMPPSPAHTASSRGFRRGSSALLQDLGGLLGPPTSRHRQRSDARSPTLQTVPQGTPFQMPSSPLSSTHSPTQSGRYTPSNLDNLMLMDPGGLLSPGPHRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ79</accession>
    <name>A0ABR3YZ79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006203</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11051">
        <property type="entry name" value="CYP59-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF107">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="564" mass="64207" checksum="F8B178AB2C0D11E9" modified="2025-10-08" version="1">MAIDLTIGHVFTAAGWLLAATVLWYLYRAYVVRSHFQRLQRQGVPMLPHHPILGHLGVVGMLMKDMPRDVHGDYLMLLIQDNWRELFDKKYTSCPPAVYLDMWPASMPMLLSMNPDMTAQFTQDVNMEKAAAQGNFLRPFTRNIDIASSHGAAWKKLRRRMNLGFSPQAIRARLPALMEEVEVFRDIMVSRAGKDGGWGSVFTLEELVTMLTLDFIGRFTLDIRLNEQTTPLTPMSAAMLDTLPRLRVFTHIGNVWSLFNPWVRFKLWYNVRIMDTWLAPFLQKRRDDLTAGKPPSGGATLVDTLFQTIATENPADANTTETFDYVVAETKHTLFAGHETTAFSLAWLFRTLAHEPTILKRMMAEHDTVLGPDPNAAADRLREAPHLIGQLPYTTAVIKESLRIHTNVGTLRAAPPGASLYGPAGSGYEGVAFPTDQCVLWDGNFAIHRNPAYWSRPLEFLPERWLTTDKDDPLHPRRNAYRPFEQGPRNCIGQHMAMTEMTMVLVLVVRTLEVEEAWDEWDAKTLKTNKKKDTVWGDRLYQVSKHGPPHVKDGMPVHVRLRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0U5</accession>
    <name>A0ABR3Z0U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynactin arp1 p25 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359631" description="Dynactin arp1 p25 subunit" evidence="2">
        <location>
            <begin position="19"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="26219" checksum="76E85EAC8FA933FE" modified="2025-10-08" version="1">MVASKVLVGSVMAAGASASLVSPLMAGIRARADLSPGSPLYNCHDNCGQAILEAQAVSSVCNDNVFLTDYDNCLQCAGPDNGDIWKYYGDSLTSAAAACGLATTPEAGSQAAVGTALPGGAGSGASSSAAGAPSSAPAVATSSSAPAAAASSTSAAQAGSSAAGSPAASSAASSPAAAASSVSAPADGGAASSAAGGAASSAAGAASSAAAGGHGSASASASAAASAAASATSGAAAKPTSGHGSSNGTAAGTGSSSGTTSAPSSVVTAGASMRSVAAGVAGIVAFGAAYVLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z152</accession>
    <name>A0ABR3Z152_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetylxylan esterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF10">
        <property type="entry name" value="ACETYLXYLAN ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382050" description="Acetylxylan esterase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="22840" checksum="1D1AC9841FDDAE70" modified="2025-10-08" version="1">MKFTLALPILAAGLATASPVADAAAAAADCPPVHVFGARETTVAPGYGTSKGLVDMVVRANSGATSEPIAYPACGGQSSCGGASYESSASQGTAAVVKAVTALNQRCPDTKIVLIGYSQGGQIVDNALCGGAGATLTGAALKAVKAAIFMGDPHNTAGLPYNVGTCKNHGFSARASGFKCSPADPSIIKSYCDAADPYCCNGNDANAHQQYVNKYGKEAAAFIQKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z244</accession>
    <name>A0ABR3Z244_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E1 ubiquitin-activating protein aos1</fullName>
            <ecNumber evidence="3">6.2.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AOS1</name>
        <name evidence="3" type="ORF">Sste5346_005672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="37"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="128"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="478" mass="50568" checksum="0C035254E0507287" modified="2025-10-08" version="1">MADVNGGAAGSNGAQPAAAAAVPDARSGMTEDEIALYDRQIRLWGMRAQEKLRSAHVLLVTVRALGNEIAKNLVLAGIGSLTIADHENVTEADLGSQFLLATPSAGEVVPPGASQEQREAADRAAAAAVVGKNRAVTVSQQLSSLNPRVNVVVEQNDVSKQAAGYFEKFTLVIVTDRDPAVLNYINTATRLQGCPFYAANSYGMFGFIFADLIEHDFVITRERGNIASKVGDRETRTRTIVDVKVEGEESGAGAAKESVTKREVYSTWYLASDASLLPHSIRSVARRLRNVTPLLPCLRALWAFQDFHSHENYRVPNPNSPEDRTEFIGLVNTKQQALGTPPVAADKIREFLQSVAELHEISAVATVLGGQLAQDVINTIGQTQQPIQNLVVFDGNNMTSSVFAMHPEMNLGTAQLATAPKSTATETVAQATGGALPVAPQLALANGNGVATSVSAVKAPVVTAPAPAGAEASAMNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2A8</accession>
    <name>A0ABR3Z2A8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ILV1</name>
        <name evidence="14" type="ORF">Sste5346_005840</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04906">
        <property type="entry name" value="ACT_ThrD-I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="13">
        <location>
            <begin position="425"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="13">
        <location>
            <begin position="525"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="606" mass="65334" checksum="7ED133CD03050056" modified="2025-10-08" version="1">MSDPTVGKLDGSTVVNGSPNAVPLRSSAAASSSTTTNGNGNGTSTPGRPTPARTPSVSGLSRTESLVDLASAEADERAARVRKLLPEEFILPNGHPDYLRLILTSRVYEVCKETSLSHAVNISNRLECKVLLKREDEQPVFSFKLRGAYNKMAHLDPADSWRGVVCSSAGNHAQGVAYSARKLKIPATIVMPEGTPSIKHKNVSRMGGHVVLHGPDFDAAKQECARRVQQDGLIDIPPFDDPYVIAGQGTIGMELLRQTNIQKLEAIFCCVGGGGLISGIGIYVKRIAPHVKIIGVEAYDANAMVQSLAKGERVFLKEVGVFADGAAVKAVGEETFRICQEVVDEVIQVTTDETCAAIKDVFEDTRSIVEPAGALALAGLKKYVAQNPSSDPNRALVAITSGANMNFDRLRFVAERATLGEGKEALLAVEIPERAGAFAELIDAIMPHAVTEFSYRFNDERAANVLLGLSLTAGNAAERVQQLSSLMARIASNEGMHAVDVSGDELAKGHIRYLMGGRSSVPNERLYMFNFPERPGALEKFLATLRPLYNISLFQYRNEGSDIGKVLTGILCPDAEVGELETYLGQIGYPWVDCTQSNVFKTFLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2J6</accession>
    <name>A0ABR3Z2J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_005744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052241">
        <property type="entry name" value="SLC66/Scramblase_ANY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856:SF9">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="30913" checksum="9FEF8AACE797650D" modified="2025-10-08" version="1">MAFLTTLAGYAAPLFLVLSPVFSYGDQALSMSRKRSSAGFSLDIPLIMLVASFLRIFYYPGAHFDKALLIQSILMVIVQLCLLKIALDNRPPPSAKGGEAPFAGLDRRDSSSGGLFAQRPYNFWQWRSPKPYWQFLLYLFLSLLAAEVLLGPFPGLYSTYSVLIGYIGLSVEATLPLPQIRANMRARSCKGFRVSVLVSWLAGDAMKMFWFFTSTTEIPWAFKLCGLFQAACDSILGIQYFVYGDGTNGSGLDVDGSGPGMMLKEKEAAFRSAAASILPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3E1</accession>
    <name>A0ABR3Z3E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047129256" description="Beta-lactamase-related domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="112"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="4">
        <location>
            <begin position="442"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="65531" checksum="3984144DB3F0BA56" modified="2025-10-08" version="1">MLSPTTLAGLAALASTAQAAVNSTPCPLVNAGLPAPSLLSTVGASYIKDAINSTDLQFLAAANGLIPYGTYESNTTAFAVEVYSVASGESLYTFSFNPPGLADTHTVGVTNIASDTVFRLGSVSKLWTTYVFLIAVGDRSWNDPITDYVPELASLVAAENNIADSVDHVDWSSVTVGSLASQLGGIARDAAYNAGLQSALGSVGVPNAGGFNHSTCGDTRLMIPCNRTAFFEDFPQQRPIFESYVSPAYSNAAFQILAYALENMTGSTMPELFDKHLVQQLNLTGTFYTVPPDNVTANGMIPYNTTYSWWNADALDEAPAGGFYSTLDDMRKVGTAMLQSTQLSPLQTRRWLKPHSFLTNPNAAVGAPWEIMRAPDSPGAPVSWMYTKAGDLGMYSSMVALLPELRLGFNVLSAGTDTTNTVRIVSDILSNTWVPRVRAAALAEAEQNYAGQYADAATNSSLTVVADSSQPGLSVTEWTYGGLSVLDLLGQLEGANASLSQKVIMNLYPSGLKQAAASGNETSVGWRATFQVLPAPLDQGPFSANCIAWEVVSQLVYGGVALDEFLFTIDADGKAVSLSPRVLEQTQTRSASSSSSSLSSKRSTRRMGAMERRRGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3J7</accession>
    <name>A0ABR3Z3J7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein mS29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005354</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019368">
        <property type="entry name" value="Ribosomal_mS29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12810">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12810:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10236">
        <property type="entry name" value="DAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="503" mass="54622" checksum="AA48F0AF129D2513" modified="2025-10-08" version="1">MAAVVNGSRRLLTRSSTTLVLLPARPRPTSLAGLAAAHPSTTPVSLSNSSSFLFSTTSAVQAKGTQQHIRAGRKSQSVKKKNKGPARAGKPILPGERKAYRKRIVLSNSNAIDVPGLESLQPQDLAVSDPVSNPNIGRMLALPDALVDQLRAIESFKATQNFQLFKKPSLLLRSDTVALTARIQSEVGEQKKTVRVVVDGERIAGKSTLLQHAQAQGFLNEWLVFAIPEAQELTTACTEYAPVPKSDPLVFTQPNATYKILQTALAANGSLLDKYTTSRAYDDLVNPVPAGSTFTELINAAKEPDHAWPVWQALWSEICNADAGLPRPRVMFTLDGLAHIMRISDYRSPAFELIHSHDLLLVRFFVDALAGNTKFPHGAAILAATTYGNTPLNPTLDLAMAQRTAEQKLKAAKAGDGTDITVPQPEPYFRHYDDRVSAAMKNVEVMTLKGLNRTEARALLEYWAASGLLRERIDEAAVAQSLMLSGNGVVGEMERVHLLSLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3P4</accession>
    <name>A0ABR3Z3P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005399</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12160">
        <property type="entry name" value="2-Hacid_dh_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="103"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="33824" checksum="A8AEC9994EA53AF3" modified="2025-10-08" version="1">MKLLYPTSLKLDVSSIEGFSVELYPYDVTKPFPDEHVDAEVLVTWTNTAANLKDGAQRLKNVRWIQSLAAGPNDVLNAGFDISKITVTTGSGLHDHTVAEHTLGLLLVAARRFDEMRDYQLQGKWPGHLGGPQPDRPAGKFTTLRDANVLVWGFGNIAKRLTPSLVALGANVKGVARKAGVRDGIEVVAEDQLPELLPKTDALVMILPGSESTRHALNADRIKQLPAHAWIVNVGRGTSVDEAALAAALNEGRLGGAALDVFETEPLPESSELWKAKNLVVSPHAAGGRPQGAEGLIAENLRRFLAKQPLKNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3V6</accession>
    <name>A0ABR3Z3V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_005634</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460600" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="16"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="99"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="99"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1894947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="186" mass="17349" checksum="45AA1F1C479079A2" modified="2025-10-08" version="1">MKSFTILALAGLAVAQFNQLPTCAQSCANKYLTGGIGNCGSDAKCICSDKDFLSGIACCLAAPGGCDAADQSSAVVFASQLCAAQGVTVPSAVTCTSTAASGSGSAAAATTTSGSGTATETSGTATKTSGTGAAATDTAATTGTTTGATTGAAAGTTTSSSTNYAPRESAGAAGLLGGVIAALAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Y5</accession>
    <name>A0ABR3Z3Y5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7702 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005609</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056119">
        <property type="entry name" value="DUF7702"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24800">
        <property type="entry name" value="DUF7702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="3">
        <location>
            <begin position="3"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="302" mass="32835" checksum="3CA3E5902AB75755" modified="2025-10-08" version="1">MSLTIYNKISIIQLVFFVPSLAIAIILSYRHGLRRSAGWIYLVILSLMRIIGASMELATISSPDNVSLLTGAQILQNIGLSPLILLLLGLITRIYTGMPENRRPSIPNARILRLLQLLVLVGLILSIVGGTSMSSTVGDELNKGETISYTVNSESKAGIALMIIGYVLLLLSALVISTKLGAIVDGEKRLLLAVFVVLPFVFVRLLYSILSAFDSSNANFRQFGGSTSAGYVVLGMCTVMEIISVIIFEVVGMTLPYVPHNERGSFLNPARAANRFDTNGQPLGEYPSQQQQYPKLQQNESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4E2</accession>
    <name>A0ABR3Z4E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="353" mass="39818" checksum="2167690295335C6C" modified="2025-10-08" version="1">MAPLPPGVAKSLEDTKVDYVRVGDSGLRVSVPIVGCMSIGNPEWADWVVGPEKALPLLKAAYDRGVNTWDTANIYSNGDSERVIAQAIKEYNIPRHKLVLMSKAYSCVGEQQFHAYPILDELRRTKDYVNQFGLSRTALFTAVNNTLERLGTSYLDFFWIHRFDPDTPIEETMRALHELVTAGKIRYIGASSMWAHEFALMQFCAEKNGWTKFVAMQNRYNMLYREEEREMLRFCRRTNVAVIPWGPLCEGLLARPLSTRGSTARSAGDAATPLRPEAETIIKRVEEVAAKKGWTMSQVTLAWTMKRVTAPIIGFSSVARLDEALSARGKELTAEEEAYLEEPYKPVEIEGHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z515</accession>
    <name>A0ABR3Z515_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="2">
        <location>
            <begin position="52"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="185" mass="20235" checksum="C35C69F925F73803" modified="2025-10-08" version="1">MKKSPSPPKGAAPANNQPTSGKPAKKSSPARAAPPAQTSSSHSPEGNKKPLFFFKPNEPHGEFCLCQWFPSPFTVNEAQMSAIVGHPVDHADPERWSPIYFHCTEQFMMYCKAGCFNDTATQKLIMATDDAKEQKRLGRQTAGFDAAVWDLVKSDIVVLGDMAKFGQNKAFTKTSRGGVNTEENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5C9</accession>
    <name>A0ABR3Z5C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="84" mass="9744" checksum="0C38C2491BA65E9D" modified="2025-10-08" version="1">MANTNNNPIDLSKIPRPTRSVEANCLSYTDDAGVQHRIYLRQGELQRASQLYEDKNWAELAKYEPYTNQGYKESDYKTIEQGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5T7</accession>
    <name>A0ABR3Z5T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF9">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="18"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="3">
        <location>
            <begin position="410"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="51818" checksum="8B6F9D7E712491B1" modified="2025-10-08" version="1">MASSGTLHNRLDALHPAIEALMRLGGTPGLSLAVFNGDIDDDGDDAAVYYASFGVRDITSKLPVTSDTRFPACSLAKAVSAAAMSILIDEGKATWEMLAKDAVPSFSEAQDTVLTQSTTLADLFSHRSGMSSLGALVGGSENNVLVSTQADMLRAVTYDICGAAIEELAQMPVANFVDKRVFLPLRMKRSSMEPPDDHDSDDNTCSCYNVLDDGTSVCIPTPRVGANGVGAASGGLWTTTRDLVKLYRAMLRSYCGDQDTPFRDIAQTEEAHVAMPGNDTSYGLGWVRTRLPNRLGQIGLNGRLFPGDMPTVGNSLERNPLVVYHQGTLPGALACVVLLPETNQFVVVLSNALALTDVPDWVAHMVVEGLLGVPYEHRVDVMEYAQRSIKVNLGWYSGVQKELAEVAHKKPLSRSLDKYVGTYVDNTDIFRLVVTLEDGVHLSWAFQGLPSERYRLTHFDGDTFTWLHTRNELHDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y2</accession>
    <name>A0ABR3Z5Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005293</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052837">
        <property type="entry name" value="Mitoribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP21, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="248" mass="26310" checksum="B96CC1008319A22C" modified="2025-10-08" version="1">MSTAAVTFTMHLPQFARTALSTSAMTPTTTTTLARMFGARTPSTPFLTSFSRSFSTTPARLDPPRQTGQSWPPARGAAAPTDAASSSETSSSSAAAAASASDSNPLKDMYSSDSPAQWATWSSNDFQTRNNLGGLNGIGAGVGGSGADSGLAATSSRSSVNGGTRIFLGPRTGRTVHVGGRIDASQAFALVGVMCYRNNVSGDFQKQKWHERPGLRRKRVRVQSRAAVYKRNKRATVERVQKLVRMGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z684</accession>
    <name>A0ABR3Z684_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005444</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF11">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="59400" checksum="C2099DE87276834E" modified="2025-10-08" version="1">MERPHAAPSLVDVAPSKSSGADLDDLELEAVGYKREMPRQFSTLSLGALSFTLTCTWLGFGSSIGTGITEASSGGAIWTMPIVAVMTVILSLGMAELASAYPVAGAQYYWSYMVASGPYKPFAAYINGWMSVIGWWMGASSVSNFVASMVLSIASLWYPNYHYQHWQQWLLYVLLMWMAVSLNIFGHHIIPLFNKLITYLSVVLLLTTTLVLFICSRNNHAPASWIFGDITSSTGWSNKGLPFLLATVNTVFSFLGSDCGAHMCEEIPNPGRNVPRVIVLPLIGGFVAAFPFAIACMYAITDVEAVLNTPTGLPLIEIYLQGTGSKAAASILVALFAFCFFGCLVGNVTTSSRTLWAVSRDGALPFSKFWSRVSPRFKMPMNAVLLSGTFVSLYGLIFIGSSTAFSAMVSANILFLQTTCAIPQAIVLWRGRDNVLPERWFNLGRFGAPINVIAVAWVLFVDVIACFPTAMPVTPSNMSYVSVVTTGLTGFVIILWFTSKRGVFQGPRVDESKLLQRRMAAIHLEGVPVDEEQAGATTTGASTVSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z768</accession>
    <name>A0ABR3Z768_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">STE11</name>
        <name evidence="14" type="ORF">Sste5346_004923</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09534">
        <property type="entry name" value="SAM_Ste11_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029458">
        <property type="entry name" value="Ras-bd_By2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14847">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01304">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="12">
        <location>
            <begin position="70"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="13">
        <location>
            <begin position="278"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="661"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="192"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="935" mass="103012" checksum="5AED090F891AB912" modified="2025-10-08" version="1">MAMLAAKSPYPPNLGGQSSAGLVSGLPTPSTAYAPTRRVLIAPAATNQSFASPTDSEFSDSDGPDSVKNWDEDRVCEYLRSVKCGDYEKMFRKNHINGENLLEMDKEVLKEMGIEKVGDRVRLFLSIKKLRTKAYANQKKRNRESFGGLDIQYVPSSGSPRLVNSGRSALPTPTVNKRYSRQVDLSSLALEGIGAKSSRPNSPPSSAEQLRSARPGRYPTPNQQAYSGQATATAVSRFPAPSPDSAPAPAQSSSRLVVAHTRNNSSMDGSLMAALPQNQDVIRVISTGGVTKVVKIADCKTCEEVMRVTLRKFALREDHERNYCFWVLNGVDPNPHNCIRLSDTELWRIIKDQKRPERNRLILRRVPSGEPGRSELERASAIAMEEMQQHGHSLPTVEKRSQLKVQKVLGESWDNLQHQQPPLSPVTYQDDRERNVNNAARDLERPAPAESTLRPPIRRKGVLRQFGGLRPPSELIASDLTTYFPDHPREDIDRTARLSMRRSARLSKVNSRLSVASNFSFASSIQDAPPIPTIADSWLNTAGQLAKVQQRDQRSIRAPHAYRDSIASSMLDTLQEEQSPMEPNRKSYVSYADSGSDTAAVSITDPEGNLIRHSFYDETTTTGSGSSSLKEVSQALDADGEGADEELQSFLAGESWDESKWMKGALIGSGSFGCVYLALHAVTGELLAVKQVEAPSPGANGQIDSRKKSMIEALKREISLLRDLRHPNIVQYLGCGSSTDFLNIFLEYVPGGSVQTMLNSYGALPEPLVRSFVRQILHGLSYLHQRDIIHRDIKGANILVDNKGTIKISDFGISKKLEATNILNGANNNKNRPSMQGSVFWMAPEVVKRTSYTRKADIWSLGCLVVEMMTGTHPFPDCTQLQAIFKIGGAKAAPTIPDEASDEAKLFLSQTFEMDHNKRPSADELLASPFLTPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7C9</accession>
    <name>A0ABR3Z7C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TATA-binding protein (TBP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tbp1_2</name>
        <name evidence="7" type="ORF">Sste5346_004527</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="261" mass="28177" checksum="7E48EA24670AAD05" modified="2025-10-08" version="1">MQAMAFTAPGSLSFPGGHTELTPPHDSFSESAAGDSSQSQSRKTDKTQPGSAESSFGTGGSDGGAVTLATPVATPSAVSSGSGLVPVLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIRDPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKLGFDAKFTDFKIQNIVGSCDIKFPVRLEGLASRHHNFSSYEPELFPGLIYRMIKPKVVLLIFVSGKTVLTGAKVREEIYQAFEMIYPVLQDFRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7I7</accession>
    <name>A0ABR3Z7I7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045798650" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15184" checksum="95678C42506DD439" modified="2025-10-08" version="1">MPSFASIIIAALASLLFAGSASAGWTQSCRNSCIGAATPNILVTECLVSGGANGNPNDQNYEWAEFDLNQVLEYAVPFLVYQQDGDFATKGPCSACSVTSGKLKCVCGTGTVPTLDLDTWMSDATGVLCFANSAFGPTCGKATSSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8H3</accession>
    <name>A0ABR3Z8H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="24445" checksum="28F58DA5ED2773F5" modified="2025-10-08" version="1">MKGVQEPNYGWKFIQNSQQELNVLRHAIWRDDVPAIREFFRPVGPDVLYWSDEGIADNPTRIYATELGRHAVLTALLDYRDSFTPEERDRALREFDIDEIANFNTRKWGTPLTTACMCARIDIVRLFLTRMPEVDINSPDKFGLTPLQTVARHSHRTALSANGYGLDPAHYLEVAESKDRIAIVRILLAHGARSRAPDKGFKRVGQTVREARNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Q1</accession>
    <name>A0ABR3Z8Q1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="109" mass="12523" checksum="73C7C6BF64116448" modified="2025-10-08" version="1">MIFANPHQNSTEMDPMRPVQTMRVDRKKLRRNAAAFARITKAWDEEPEYLSSEMADISSIKSRLRATIVDWLAKTKAERKEAGAGSVQVEFYLRKSLKKKALLVRDLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S6</accession>
    <name>A0ABR3Z8S6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02205">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="550" mass="53540" checksum="F5541DBCC313BBF0" modified="2025-10-08" version="1">MPPPPPPPPPPPPGGMSGMPPPPPPPPPGGLPARPPAGKGLNTALLGDIHKGKALKKTVTNDRSAPVVGKSSGGGAGPSPLGGAPPIPGGGAPPRPGGGLAPPHAGNRARSNSDQGGMDSAGPPQLAGLFSGGMPKLRKTGAGVKTGADTNASYLSDPEDSRSSAATPPRPPAFGAPKPPGGAAPKPPGRPAVPAPSAPSAPPPAPGNPLGAGFHPSISNLRKVSARGAGDRPFSSASQIIIGNKGPPPPIGKKPPPPPGSRKPSSSLLSSPPPTGSAPPIPSAAAPPVPSAPPAPPPPPPPGGSSSAPPPAPPPPPPPPSAMPSSPPPSQSLAAQAMIRAQQQQQQPASPPPPPPPPPPPSNSAPSRPPPPPTAPPPPMAPAPSHSPSSSFSSAPPPPPSAAAPSAHPYSNGASTASSSAANLPPPPPPPPQRAASNSISGGSNPMRVSMLDPSAYTLMPNGGGNSGNSSALNSPSPTRANTTAGGGNSGSLSPRPQTSGGGVRYIVQDTRWRFVTEDKFPVARTFTGAPKRYRAGRGSSVPLDLSLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9N2</accession>
    <name>A0ABR3Z9N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="19"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="523" mass="56750" checksum="E19337695EB73AFA" modified="2025-10-08" version="1">MSSNGRQTPLGANRRVLFITALMALANTQYGFDASVIASFQAMHGFLEIFGYPLPPPKTGYEISTKTQQLITSLLNVGTIVGVLFTGPFSRVFGRRAGIWAGALLGFAGCAAQLASKSVAGISVGRALVGASNAFFITFANAYIAESVPAHLRSICSGVFGVTTTVGGLLGTIVPYLTKDVPGRLCYQIALACLFVFPLCLAVGTIFIPESPRWLLVQGRTEEAERALATLRDNSLTPTQFHEELAEMEHGIQEEKALASSTSLMASLADMFRGTDRRRTLLCIGTVTSRAASGVWVFISYGTYYYKQAGIHDPFAMSMYNLSAAIIGAIAAVLCSHLWLGRRTMILFATGAAVLTMIAAAVGGTVAPSPGNQPAAKSFVAFSVVYNVLYGSFAGAVTWPISAEVVSSRLRVVTLSVATAIDYIFAWLTAFCSPYFINPASLNWGVKYCWLWAGSNALAFLFFYFLLPEMKGRSLEEIDEMFAKRVRVKYFKTYECDCSRVERDVAETRVEESKPYVSWSRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA12</accession>
    <name>A0ABR3ZA12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF92">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="808"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1065" mass="117467" checksum="64EB8D9E1BFB2B0E" modified="2025-10-08" version="1">MSDFTIATHRGALNPAQDRRAEYRYLNTIMEEADFSDASPVRAQNSIPLKIQQQQLYQQHQQRLHEERIREDRRHGDNEEREQKVEMWLSPMSDHFPTPRGFHFLSAPILPSSPSSASMDNDADLDDESSPDSNSSSSPWHHNGSVSTDVTEFDDIYNASDDDSTTRKRKLRASGIGRYSSASRRTSSAMSRLSSSSEESRKMLPQLTIPKRPTISLADPDPKLCTSPMAPTPSAQVPMSPAIMSFMQKHHALDVPTVSAPPSLDGSLTSEQMSQMSAQMSAPPTPIIGAADGDDENNSGWAGVQLQPGALATLQSLARSDAGSVADMSLEPERVIELPTEEEQQPVAEMSENRSQPLLNLITSGLPRHTVPFSPVQQRSLAGLTRLEIPSPGGFFSGLSPRTRHTWHMPGMTPIDSAHPPTSGTAEQFYRLPWADASAPPVPRIVKERPLHMPISADMSNSPVEQFIEAPIVESEDPVTAVRVQKTPVTAQLVMPEQAPVALSETVVEPVEAVEQEAISPVEEVIATEIVNDYLATDAQKMQQIALGHLDRTEMWLVAQRAYLNGIADLTENVEEIPSPAEAEEEEAPEVPPKDEDLKAVVSTAITRKKTVRFSEAVKSPAMPRTLPSAMVHQESAYYRAFTDCMVRSSFTDMFINRLPRFEALQAQRLLLREAHRNQLLGKYQLTVLPQSAKKRMSANVVRGDDNLLDDPEKIRADKETDALSQMALTTWHVASQKLLNGGRLISAPVHKRLARVSRMAPGPNGVSRDRARILDLGGQATCDWAWHVALQYPNTKVYSVTTKAIRQLSNANIRGPSNHRQVAVEKLTKLPFDDDQFDLVRASELYSILKFVGENGEDEWETCLQECYRVLKPGGYIEFTVLDSDIINAGPLGNAKSVEFGFVLQTLGYDPSPTKMFLGRLDRAHFTDVRRAWTCLPVGPRPESLTKPPVARDLTGAVIPTVQLDAMVHGSTDNIAAVTGLAGSWSWERWLLRAEMEKTAGDLRLADTVTAGSAIREAGKSLDGVHAIVEEGRATGAAWRMLRGHARKPRSEVGTINLMLDMSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA43</accession>
    <name>A0ABR3ZA43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar-sorting protein SNF8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dot2</name>
        <name evidence="3" type="ORF">Sste5346_004297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017215">
        <property type="entry name" value="ESCRT2_Vps22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR017215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="256" mass="28046" checksum="71CA338C81B93C7C" modified="2025-10-08" version="1">MSRKGVGLAAFDRSRITSAQYASHGSNLRSTNAQALETQLAVFRSVLQQFAQTHGKDIRSNPTFRAQFALMCTAIGIDPLASSNSASGGSIWAQLLGRTVNDFYYELAVRVVEVCAATRAENGGLIEVRKVRDRLALKRMEGAPEVTEDDILRAVGTLEPLGSSYSVIKVGSKPYIRSVPKELNTDQSAVLEAVQMLGYVSVSMLMVNLKWARARAQTAIDDLVGESMLWVDKQAAEWEYWSPGFMLEGHDAILDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAH0</accession>
    <name>A0ABR3ZAH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Dihydroxyacetone kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_003961</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="13">
        <location>
            <begin position="9"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="12">
        <location>
            <begin position="395"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="357"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="63871" checksum="E4CAB737F8B77635" modified="2025-10-08" version="1">MSTAHLFNSADGLVVKALRGLVAYNPSLALDTDLRVVYDTAFDRSKVALISGGGSGHEPAWAGYVGTNMLAAAACGDIFASPSTKQILSAVHRVPSDVGTILVITNYTGDCLHFGLAAEKANASGQHKCRMIVCGDDVSVGRGGGRLVGRRGLAGQIAVLKIMGAAAATASRASLDDVYGLGQAVAKQLVSIAATLDHCHVPGRTEHGALAADEVEIGTGPHNEPGYRKLKPAPSAEDLVGNLLKHCLDETDAERAYVHFDTQKDEVVLLVSNFGGMSQLELSALVDELLVQLQRDWKITPVRVYAGCLETSLNAPAFSVSLLNLTAAAADEQNPYSVEELKGFLDTRTSTYWESFSGAQAQRRPRAEQFVKSLEGEEEKSHSTTNGGDLPVDAARLEMALRQACNDLAAAEPDLTKWDTVMGDGDCGETLKTGALSLLAAVDGTEGASPLAKAGSSVAVLRSLEHIVETKMGGTLGGILGIFLVSLRAAVEKAVSENKNGGNVKDTEVWGNALTTAIDHLGHYTPAKVGDRTVMDTLIPFAQAIGQGGFKAGVEAAEKGAESTRKLTPKLGRATYVGAGKDASDLPPDPGAWGIMVAIRGLYNGWQGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK9</accession>
    <name>A0ABR3ZAK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily</fullName>
            <ecNumber evidence="2">2.3.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MFSD9</name>
        <name evidence="2" type="ORF">Sste5346_004588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="715"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="823" mass="92098" checksum="6101933ACD934002" modified="2025-10-08" version="1">MEESTDSSSACICSTLRQLVKNYETYDDKRANSLAAALAPQLNAVLGDLRTLLSRSKALSRHVDYQIIPCNQRTMKALAVEAVDLGPVDALGTRYRDDISGFWSLSADKDAVHSGLHRRLLCTVVFLRSKLNVLESASISTTLIRPQKNCTELINSGRKYIKIARKLGSLGSLFWLPLDIPHSTYERYLNMDDEPVFDHLKSLAPSSTEDDRYSDIVQQLLLSQFLDLPPSCSHHNLFPHYSDVLPAPDQLLLLLSALGGSDIPLTLFDSIRSPQRRWSEHGEMATTSAAEFGLPPGLIRLCHDEASLRQVLRESPHITEHINDDGISLLSLSPDMMAFFSSALLPVTVATLDDMALRLICFACPPCYEGNTVWPDKVKRVIWPLLDAKTARPDLSQEPSLKTQAVEAVLYFCERDGVALRRVALIRARSLLKRSMPFYIHASVVLFQSILHRLDGELAMSQALLQEFASRATGGSPKSQGQKKAGLTRRDMAIQGRLHISYIDNKIRAYDMDVSLQMYKWEAAQPLSMLDIQVTSRLQGVAARFFQSVGDFPAAAASLDQYLSLLSSLDASSSANTRRLIVGRLADIYCELGDPCKAASILQPELDATGTADQPRRPYRRLLLSLVEVNIALEQFDEAEQILSQLRQLQEKALPPPLQLDNIHDQQLYVRGLLASARIAHSRPRPDLDLDEAIRRWHHVLHEIRHMHTLNTLQSQAQAQAQAQAQASSPDQGSFTGSFTEHFTEAIIHLSLAHAQMAIGDSDGTRHSWTVGMEILRREKCEFWIPIVPTLWLKKIVMQVHEQLGWSFRMMLPGGKPDMTWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB71</accession>
    <name>A0ABR3ZB71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004123</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008902">
        <property type="entry name" value="Rhamnosid_concanavalin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF6">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05592">
        <property type="entry name" value="Bac_rhamnosid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25788">
        <property type="entry name" value="Ig_Rha78A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010631">
        <property type="entry name" value="A-rhamnsds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="5">
        <location>
            <begin position="155"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase concanavalin-like" evidence="4">
        <location>
            <begin position="328"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="6">
        <location>
            <begin position="431"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="7">
        <location>
            <begin position="785"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="891" mass="98977" checksum="C8524CD7EAD0A7AF" modified="2025-10-08" version="1">MGDFILDTVSSRAPASISIAELRAEHYESGFGIFHATPRLSWRFAATSVRDWRQTSYEVVVTRQGQSESFHVSSNTSSLVAWPSTPLTSRETAHVRVRATGTDGSTTDWAELTLEAALLKRSDWTAELIGGPPQPVDQPKKPFRLRRAFTYSGDAETTRLYATAHGLYEVEINGQRVGDHVLAPGWQSYRHRLHYQTYDVTPLLRPGHNVIGVYLGEGWFAGRLGRPGTSNIWGDRLGFLGQLEVDGRVVCKTDADWEVLTEGPVLNSEIYNGEEFDSRLVDLEWSASGVSTYVVHAAILPFPSAELIAPETPPVRRLTEIQPQQIITTPSGKTVLDFGQNLAGWLRVNIDIPGTDKDTVVIRHAEVLEHGELGTRPLRTAKATATIHLGGPTCGYEPRFTFYGFRYAEVTGYVEVKLTDFSAVVISSDLRRTGSFECSHDLVNKLHENTVWSMRGNFVSVPTDCPQRDERLGWSGDLQVFAPTASFLYDTAAFVGGWLRDLAADQHDLKGIVPNVVPSVPMPPNDNERRPMAAWGDATVITPWDLYQFFGDATFLRKQWDSIVQWLDCGVPRDAHGFYSTETPQFGDWLDPRSPPALPGHTPTDPYLVANAYLVHVTERAAQIAALLNETEAAQRYGSDARRLRARFRSEYVTPSGRLSSDTQTAYVLALHMDLYDSPAELSTARHRLDWLTRWEAFKINTGFCGTPHILPALAKVDMLPTAYRMLQERDSPSWLYPVTMGATTIWERWNSMLPDGSINPGQMTSFNHYALGSVCHFLHAHVAGLSAEEPGWTRALVRPRPGGTVRWARASHDSPIGLYSVSWKAEDEMAMATFVTIPPNGSAHIVLPGIDVVVGSGEHVFETEWHPDPEWPPQVIQGAQGKPVEAVFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC27</accession>
    <name>A0ABR3ZC27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF38">
        <property type="entry name" value="POLYAMINE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="122"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="562" mass="60797" checksum="2F15E2519A2871A3" modified="2025-10-08" version="1">MSDLESGRIPVGTTSTTFHQPEKEDSANAASRSVHSSDSATIEGVGIGMAADQASDGAIVEKTAGLTDNEKLAVVEDGNNTDGSNALPLPLTIDADGRPVVWDWATDPANPYNWSKGRKWAQVACFASVAFTTSVGTSIMSPAHTDLMLEFGISSTAAILPLTFYVLALAIGPVIIGGPLSEVVGRYPILLLGTPFGLLFTVGAALVPTSSLAGLCVLRFFAGFALSPSLAIASGVLTETFRPVERGLPVACFIVTPFLGPGMGPVLGAFATRKGWRWTQWTIVFFAAFSILLTIAIGRETYHPVIKRRRAKELGITLPAEDLRPDIPWSQRIYNFITIGLIRPLHMLVAEPIIGLSCLYVACEFATLFSFFAAVPFVFQIVYRFGREECGLVFISIVVGSVLGLLTVLLTDIFIYKKRQVPRFHPAPPPPEHRLYAAMIGSFGLPVGLFWFGWSGFHGVHWISTTLAIVPFAWGNICIFISLMQYMGDTYTGSIVASGASANSLARYSLASVFPLFTIQMYEKLGINWASSLLGFVAIALLPVPWLFFKLGPRIRAHSRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC98</accession>
    <name>A0ABR3ZC98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Sste5346_004186</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 16" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="13 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045791645" description="Chitin-binding type-1 domain-containing protein" evidence="17">
        <location>
            <begin position="17"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="18">
        <location>
            <begin position="182"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1897448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="395" mass="41742" checksum="75E1112212424181" modified="2025-10-08" version="1">MQLLAAIISFLLLVSAETVGPKCSPVTWSKEKRGEHQAHIGDAQKPKFTPRKGVISTSNVAVGDVNCRYDATTGSKVSSATCAELAKKYGIREEVFFKLNPSVLPDCSNIGPDTDYCVAGFIEPLRAKDGKCGPPNNNATCLGTAAQCCNSETWTCGKTEEDCSRGICYEGACAGDKVYSTDGTCGVKDGRIRQCAGKHGNCCNNDGKCGTGEAFCGLENCQGGDCVKPEQKDYKPGAGTWLGGNTTDGTCGGTNKFTCNVVYGNCCNKDNICGSNPSDCEAGCQPEWGMCKGAKYTPPSGTETSDKPMSTITYQGLPECGKSCMMHMLVQSTSLECGLPRAPCLCSNDVFLIGLAHCAHGICYNETMAETVIGYWQAYCFNETTTSTANAGPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCY5</accession>
    <name>A0ABR3ZCY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044995238" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="57733" checksum="81DD4369603F48F7" modified="2025-10-08" version="1">MKHSHILSIFLAAIAKAAPFSRGDTNATDSLTIATLTGVFTGALSDEYPNVREFRSIPYAQPPIGDRRWLPPLALEPSGRHFYSLRYPASCPQYLTTHPSLWNANITDFAIGTRGQSLLAGVQAQTSSEDCLSLAIWAPQPNGSTTGLLPVAVFLPGGDFQAGGVDVPYQMPAPLVSRRGDLIVVTLNYRLNIFGFPNAAGLHDQNLGILDQRMATEWLHANIKAFGGDPDRMVLWGQSAGAVAADINNYAFYDNPLVAGYYLMSGTAAVAGVKADPLYSNFSFVAQNVGCDFGTGTSRDPDAELACMRRVPADLLTNFLGHYAENATKPAIGFRPVPDERVYFANYSARAAGGFIADRPALVSTTANEDAGLYTYPASNLTEGPYMPAVDKGTLSVFVCPAANTTRWRGALPGRTTYRYQYAGNFSSVTPFTWMGAYHASDIPMVFGTLSRRPEDERTPFQEEVSATMEDHFAAFLNDPENGLRARGWLPDDGNINGGYMMRFAAGSTLQKGINSLEVDGACYGQGTYNHSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDN8</accession>
    <name>A0ABR3ZDN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003387</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="484" mass="51805" checksum="575BD42B91A739CE" modified="2025-10-08" version="1">MVATLSSPKLLINGELVEASDKKTFPLYNPATREKVADVPEASEQDANAAVAAAKAAFPAWSALDPSARAGYFKKLANLLRAHSSELAELEAQAMGRPVAQYFDAFAAAGNFDHYAEAWPHIQGQASLNTPGYVTMTLRQPMGVVAAIIPWNVPLLFLSSKCAPALISGNTVVLKSSEKAPLTAARVAELVIEAGFPPGVFNIISGHGLPSGAVLSRHMDVRALSFTGSGRTGRLIQEMAAQTNLKKVTLELGGKSPALIFGDADMDKAVEETVNSIQWNSGQVCMANSRIYVEKSAAPAFTEAFSRRFQAVNAGNPLEKTTNHGPQADEVQYKSVMAYIEEGKASGGQLTLGGNGTLEKTGGFFVEPTVFVDTPETARIMKEEIFGPVVLINTFETEEEAITRANDTEYGLYASVYTKDVDRALRIAKALESGYVGVNCTSPATGRDLPFGGYKMSGQGREGWLHSLDHFLETKSVIIKVAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDQ7</accession>
    <name>A0ABR3ZDQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="26"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="464" mass="50672" checksum="D98F93277B5318B8" modified="2025-10-08" version="1">MAVQASQAPAAAAADAPATPRPQDLRIAIVGAGMGGLASALALAKKNFTDIHVYENASGLGFVGAGIQLAPNLVRILTRLGCWDAIEKGATEVRETSIRNGATDEELTHVHMPNIRKMYGFPHCTGHRASLAGSIYDACLKEKSITFHFGHTFDEITAYEPRVTFTLTKRASADAAPETVTEVCDVFIGADGVKSKTRTQIMGALGHEASVEDTGQAAYRIMIPREKMEHDPEMLALIDSNQVTRWIGARRHWIAYPVENKTIYNMSSTQPDEHFAAAPSATYTTTGSKADMMSVFSDFCPLVQRLMDLVPEGEVCEWKLRMHKALPTWVNGTVALVGDACHPTLPHLNQGAAMAIEDAAVIAEVLSRAPDNEPATLHRCLQIYEFIRKKRTTTLVDLAAFSGRTLHLGDSKAKEERDKMFADSKKSGANVPDKWASPEVQKMIYSHDCMKLAGDLFEGLYEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEW8</accession>
    <name>A0ABR3ZEW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003161</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF28">
        <property type="entry name" value="FRP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="295"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="395"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="568"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="655" mass="72153" checksum="70ED3BDB763AC084" modified="2025-10-08" version="1">MAWPWEFQELTPEERHTRRLVLDRYGHYGALLSVSPMVAMLLVRIVVWAVGFVRTRYAQSCSGSSVGSAGSPSSNARYDVIPDSPSLKSRRLTARGSWETWFRRAKWWLSDDVVIFGQGLGQRDLWVGGGLWMAILLVLCVVETGRDYMHLTKRFGIIGISQLPLQYILALRHVSPVLAIFGTSHEQVNRWHRMLGAVVYSVLILHAVFYLNYFAYMGNFWQRFLRPVIALGTAAIISMTLLTTTALAFVRRWSYRVFFITHVAVAFALPALVLFHAKHASNYVAAALLLLIADLTMRKIRTVTTEAHIETIPGTELVRLTAPIPFSKLEKFRKHPGSHVYMNLPGSARPSTNLLSPTYILFELLFNPFTIAAVNDQTSDLTLVVRARKGPMSAALSRHARPAQLPKSGDNDADEDNDDETTPAIPTVSRHELNAAANTSTSTIPVNLEGPYGSSAYFPELTPHNFDRVLLVAGGVGATFVVPLYRSIIDEAAASPNGGSLKVDLVWSVRGAGDATWAVVSGQDGSGRSLLQDRNVHIFLTGGSGSASAGAAGSAAEAAIELTALCREQQQQATSPHDRRPPPSPHSRFVPPGASNRQRPDFHQIVDDVFRHGSEERVAVLVCGPEALVQDLRAAVSTWVHRGRSVWWHNESFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP1</accession>
    <name>A0ABR3ZFP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phenylalanine ammonia-lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="745" mass="79290" checksum="529AC21C34EBEE47" modified="2025-10-08" version="1">MAAYATSHLQTVCREWASVRAAWTGAQAVSVTGDDLMIADVVAVALHGVSAQLTTDKAVRGRMTASVDFLASKIADGKVIYGVNTGFGGSADTRTQDFHRLQSALVQHLNVGILLPSDKGQPTSSTPSTGVADVDLLLRSHALPPAVVRAMMLVRSNSLARGHSAVRVEVVESLLHLLTANMTPVVPLRGSISASGDLSPLSYVAGILEGNPGVFVRCQEKTVHDSHTGKVGQLPSNSLRYLSADMALQAAGLDPVRLQAKEGLGITNGTAPSAAVASLAVHTANQMAVWTQLLTAMGTEALSGSANNYDPFISRTRPHRGQSEAASTILRFLQGSVLSPGNTEPARVGLAQDRYALRTAPQWIGPQLEDLMLATLQVTTELNATTDNPLIDVGSDDQSAGGAVYHGGNFQAMAVTSAMEKTMTALQNLGRLLYAQSAELIDNARNRGLPPNLSPDDPSTSFICKGFDVNMAAYQAELAYLARPVSGHVQVAEMANQAVNSMALVAARYALEAGEVVGLMVATYIYVLCQALDLRCMQREFRATASRSLSDIVKNTFASSQHGSAQLTALADDLVPQILNCWDDHSHLDLHARGETAARDTVGAVLAGFASLSLPLPDGMALIKFQELAIANMVATYAKTRKLFFSEPARASTYLSPASRVVYEFVRLDLNISLNRGIDDHPTLVAENKAVANGHTNGHANGYVNDFKDADRTRILGTMASEIYVAVRDGRLFDRVVSLCEESNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGJ4</accession>
    <name>A0ABR3ZGJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome regulatory subunit 6B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPT3</name>
        <name evidence="9" type="ORF">Sste5346_003097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="198"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="421" mass="46828" checksum="31981EEC024E3A4E" modified="2025-10-08" version="1">MGDTLIETPLSQAAPHKKTAPSTLPSLGNFEGVVVEGGDDYGTLKKLQGQLEYIQLQEEYIKDEQRSLKRELVRAQEEIKRIQSVPLVIGQFMEAIDQNTGIVQSSTGSNYVVRILSTLDRELLKPSSSVALHRHSNALVDILPPEADSSIAMLGADEKPDVTYADVGGLDMQKQEIREAVELPLTHFDLYKQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTTANFIRVVGSEFVQKYLGEGPRMVRDVFRMARENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTANVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFSTIASKMSLAPEVDLDSLIVRNDPLSGAVIAAIMQEAGLRAVRKNRYNIIQVDLEDAYSSQVKTTSDENKFDFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHA8</accession>
    <name>A0ABR3ZHA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF273">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN SAMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="242"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="629" mass="68683" checksum="D7FDE158F5C55853" modified="2025-10-08" version="1">MANSTAASWPPAGSRAASLLEKRQELADKLAESSYDILLYLHRAAIYADLAYPDLAAGDAYRALLLTDEISDESFEYHDQTHEAMSPYVSGEKALPDFLQKGAAKDLASGVAELSISSDLDETAELEACRKLASTAAIRCYQILSLNLLLCGCLRSAYTFCERGLAAGPEDKDLQQTKALIDTAARKRYGKADDASFEYNPTDLPDRGLVRREVYPWNTYEPDRFSAESLAFLNDELSRAAPKCEVRATELPILTEKDDEDKNAASGEIPTCWQLGVFAKEPIAAGEAVLKEYSLLTANNRLKESACDACGTELPTLAEVGKKKKKSGRSARGDANNDGGELVAAPVACPDCYDTVFCDEFCFEQAQEKYHPAVCETDVDSIAKDPEDARDADDALYVLLLARLLAMATHQEAHPLEVDEIKYIWGDFVPPQVNAGAGSDANVDDDTSVSPSSPHVVAMAGGGGIPPAAWSLPFSFEANIATPLHILEKMDLDVFADLAHYDVWVLNSCYSKFRGTASARKSRRDGRPDVAAVHPLWCLANHDCDPNVTWEWGGRMVLWAREERVKLDPNSTEKHPGGIEAGHEILNHYCDVDLPVQLRREWASGSLGGACMCQRCRDEAAAEANKAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHG8</accession>
    <name>A0ABR3ZHG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BRO1_2</name>
        <name evidence="14" type="ORF">Sste5346_002633</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit apl3 and beta-type subunit apl1), a medium chain (mu-type subunit apm4) and a small adaptin (sigma-type subunit aps2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14833">
        <property type="entry name" value="AP2_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027156">
        <property type="entry name" value="APS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0168">Coated pit</keyword>
    <keyword evidence="6" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="143" mass="16911" checksum="D3D03C94946FC361" modified="2025-10-08" version="1">MLSFILIQNRQGKTRLAKWYVPYTDDEKIKVKGEVHRLVAPRDQKYQSNFVEFRNHKVVYRRYAGLFFCACVDTNDNELAYLEAIHFFVEVLDAFFGNVCELDLVFNFYKVYAILDEVFLAGEIEETSKQVVLTRLEHLDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHK2</accession>
    <name>A0ABR3ZHK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="519"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="730"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="521"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="739"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="835" mass="89933" checksum="CE664F8005E36C49" modified="2025-10-08" version="1">MASDTRERQRRRKIVLACEPCRERKSRCDGRKPICSSCERRSLGLEQCVYTIGNARTASSEDYTKALHERIRHLEHACSLYGIEVDSTGRVSLLPSSRLQPPLSAPASASASPAMLAGGRRGGVPDEQPSATPPNMPATGKSGTSDITSPEPMDPEDATGVTAMGTVLSEEDLEGEGAIDSFYGRSSAASFLKEAASALPQRQAWSGASASTASNTTAATTSRSSFFASRSTTAPSPLRPIPPPLQPPPIFAPPTLRFTDIDRFALPPRALGDHLIQRFFSRIFYQYPFFDREAFEHAYQRLWQVDDAETRARTATQQQKFEGLGLGSSEAGADSIIFHCALNAIFALGCCFSDLPPVERAAAIDVFGNRSKTFVGLELINYNNLGVVQAMLVISLVLQGTPYPNRCWIAVGMACRVAQGIGLHTEEASPSRRLRGERMRLMRQRTWHGCVVMDVLVSMTFGRPPMTSSLSIAPEMLNKAPDSSNPESLRLAFYYEGVKLSVILEDILQRIYKPWLTRDATNSSTNTSTSTSTSTSTSTSTSTSTSTSNACNNALQTHHNLDTVVEIQGQLDQFERSVTPFLSWTTHAEIPGAVSDEDRLIMGISQNVLHARFIYLQLILYRPILSQLANPDANPATASGAKSPGQSLLTRDGLRYSFAIEYACAAGLVLIVARSCPDLWQSLDRDEIASLWDKCQSILQDQALFSASARKSLDLLLKVNEHALLKQAAGENDSQAASGAGGSGFGNDSGIGGREGGEGGGDNTSFGNSGLASQLLSGTDGDGMAAAGGSNMQPGQFDFLAQMADLNAPSLLEDTYAMGPLFAWDQNIDFSNLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHL3</accession>
    <name>A0ABR3ZHL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF24">
        <property type="entry name" value="3-PHYTASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="659" mass="73218" checksum="91DBCB2A6AC5C085" modified="2025-10-08" version="1">MAGPISSIVNGVRSLLDGSGGRSYYNRNNYYDYEPVASPSSATGFLSDDEDEDADYNHFDQRRHRKRRREPMMIMEAGSYQNDSGRRSRRGRQYFDSDFRDGVFDSIWARGNRRFLKLTLLAAMAGLMLYLGAIVSRIIAASRAAGRIPPSCDTPDHGYQCYPAVAQYWGQYAPFFSVPSDLSNTGTKKPVPPQRADSSPFAPPQHTPKKDPSSAFLPPGCHFTFAQVLSRHGGRDPTSGKSAAYAALIARILETVDDFEDGPNGKFAFLKDYKYTMGADELTRFGELQMVHSGAHFYQRYRSLLQPLNTETSHVDPFVRSADQHRVVLSAINWIQGFQGARHQDDVKGKSSHTDKDNESEHAQIVLLPEEAGFNNTLSYNGLCKKFTSHAGSVAQRTFAATFVPAITERLNRGLPKANLTDTETVYLMDLCPFETIADGEEEEEDKDGEIVKKIVGGGRRLSPFCHLFAETEWRDYDYFQTLGKWYGFGDGSALGATQGVGFVNELIARLTSSPVDDHTSTNRTMDADPATFPLDAKVYADFSHDNDMANVFAALGLYNGSAPVGGPSNTTRVEPEDLRGYAASWTVPFAARMYVEKMVCDGDKSDDSEEFVRILVNDRIMPLPNCGADQLGRCRLNRFVESLEFARSGGNWDDCFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIU5</accession>
    <name>A0ABR3ZIU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF22">
        <property type="entry name" value="CAPSULE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="335"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="647" mass="73006" checksum="80DAB16FD047E731" modified="2025-10-08" version="1">MFFRNAGTVFSGRRGPESFSSIARFAFIAGFVTLAATGFLLTQYHPDKVRNVAAKLPHLNLNPDSEHQQAIAEYERLVFNVSDNELHPIDRLIAASRQAHDALVAKQSFDVATAAAKYRERRGRHPPPGFDKWMEYATSHDAIVVEDFFDRIYHDINPFWGLEPNQLAGRAQSWHHVVRVRDGKATGVGDITGRVPWLKLWTDLVSEAAPYLPDVDMPINYMDESRLLVKWEEITALVEKGEKAREMVEPEKALRKYRGLSFIDNAKNANETKPYDPDWIHNNSPQYWDLSRAACAPGSPSRDVPALKDFSRSPSIPFDWHPAYSSEGYVKNFTGSADSCTQPHLRSLHGTFIEPLSISTSTELIPLFSGCKLTTNNDIIIPGAMYLTSDPFYSGGNGHGPQWSQKKTGIIWRGVASGGRNKKENWSHFQRHRLLEMLNGTTVTALEHDGARAMTFDMAPLQMYDYKRRRNMSIGDFLTEFADAGFTDLLCFPAGECDYITPHFKALPSKPMAEQYVNKFIPDADGNSFSARFRGLLLSTSLPLKATIYAEWHDDRLAPWQHFAPLDNTFQDLHAVLDYFTSTAKGDAAARMLASVGKRWGEKVLRRDDMLLYTWRLLLEFARVCDENRLKLGYTDDLIPVAAEGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ11</accession>
    <name>A0ABR3ZJ11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MRT4</name>
        <name evidence="9" type="ORF">Sste5346_002492</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="8">
        <location>
            <begin position="126"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="249"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="31429" checksum="1BDA836FC0B06010" modified="2025-10-08" version="1">MPKSKREKVLHMSQVAKKTREHKDRLFNNVRDAVPEFEHCFVVRVDNMRNNYVKDVRQEMTDGRIFLGKTKLMARALGTTPEDAMAPGIDRLAARYIRGTVGLIFSNRKPDDVISYLESLSPVDFARAGTVASRDVVIPRGMLYSTGGLVAEADDVPMAIALEPELRRLGMPVRLLRGKVVLEEAPENEEGHVNDAAEGYVVCREGQTLDSRQTRLLRLFGICLSEFRIETLAYWSAATGEVTELQPPLPVSVKGASGNNGAAGATSSAPETEDDEDVAIEDAVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK08</accession>
    <name>A0ABR3ZK08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002285</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="118"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="635" mass="67041" checksum="3AFFCCB784D8C2E0" modified="2025-10-08" version="1">MSDTLKAVPAATVTGAGSASNSRAPSPTLAPSRTSVDKELRDEKIPTTSGTGSGEDEEIEDEEVENVNIEAIRAAADGHELGKVETSKSHAEGGLAVAKTATREDGSEYPTGARLGLIMLALCLAVFLMALDNSIIATAIPKITDQFHSLNDVGWYGSAYLLTTAALQLLFGKFYTYFSIKWIFLGAIFVFEVGSLICGVAQNSVTLIIGRAVAGLGSSGIFSGALIILAYSVTLDKRPMYSGMIGSMYGIASVAGPLLGGVFTDKVTWRWCFLINLPIGVITLVVIGFFFTDPDRKNGQPTAARVTTADAAAAADAAANRTFWEKIRPFDPIGSAIFMPAIICLLLALQWGGTTYAWKSGRIIALFVIFGVLIIAFLYVQYLQQDDATVPPRIIKKRSVWAAGWYSFATGAAFLASVYYLPIWFQAVKGASAVSSGLMNLPMLISLVLMSIIAGSVVTVVGYYTPFMIAGSVLMPIGYGLITTFGPGIPHSKWIGYQIIAGAGVGLGMQQPLMAVQTVLDIKDVPTGTSVIVFLQTLGGALFVSICQNIFTNKLQENIIKLVPGLDPTTVLAAGATGIQKVVSAAQLPGVIQAYSNALTQTFVVSTALAAMTIIGSATIEWKSVKGKNVEVGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK71</accession>
    <name>A0ABR3ZK71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33930">
        <property type="entry name" value="ALKYL HYDROPEROXIDE REDUCTASE AHPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33930:SF2">
        <property type="entry name" value="BLR3452 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="172"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="247" mass="27202" checksum="9A19E4A8EDE54796" modified="2025-10-08" version="1">MGEDSFHSGWQSLLATDPQFFRASLSLVSVPRKKQHLSPKDQALVGLAVDSAATHLYRPGIRAQVAAARKAGATIEEVLEVVELTSTLGIHACNIGVPLLVQVLREEGLHTDAITKPFDERQQLLQQQFTDRRGYWHTFWEDFLRLDPEFFEAYLELSGLPWTKDVANAPVPGKGALSPKLKELIYCAFDTAATHLYVPGLKLHMKNALGYGATPGEIIEVMEIATLLSLQTAHETVPVVAELYGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK92</accession>
    <name>A0ABR3ZK92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="39206" checksum="F6DDF55E46A763D4" modified="2025-10-08" version="1">MSPPRPSYYTNPLPGPTAGRWMPPFILIKLEIALRETIFLKDHLQYASINDAALRRVLTPTQRQQWYVDYVNPVDNLRYITELLEEYGNRFIQFYKHCGGSEKSKPSALLQRTALCMHDSAMMDMAVRNGQANQHNGWQGWTPPAPAALKQEMGCVPRATRSWPARLFTTRVPEGILPYFRWIPSPTGWHRNDKTESLDPLNGLRMVPPEPNLEGQYQEPDGTVGDIVQTMILPCGCIGNMDGFDEDRFNELHDFMQTAWPTWQLHWRELYAQGELTQQALDMLLTNRYETSLNKIRAFDVNVFATTRGKETMLEYANMFWRLCGYICPRRQRPEWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK0</accession>
    <name>A0ABR3ZKK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF1">
        <property type="entry name" value="OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="372" mass="39815" checksum="B387E5CBD8A0632B" modified="2025-10-08" version="1">MTTKTVQQWTTVQDGLENLTRDTAPMPTPGPDEVLVKIHAVSLNYRDTEVCMGLYGHHKAIDAGGPQPLVPCSDMCGTVIAVGENLEIVHKVGDRVVSVFNYTHRTGHAREVDMSVGLGLPLPGVLQTYRVFPSVGLMPAPSYLSDIEACCLPIASITAWMAINGMRPLGQPGGKGEVVLLQGTGGVSVAGLQIAKASGATTVVTSSSDDKLEVAKKMGGDYLINYKTTPRWADAVMEKTGGHGADIIFENGGASTLRQSFDAIAFGGIINCIGYLGGKTNTVSEGDDMTGINVLALRRNMTLRGILNGPRDRFEEMLAFYNEKKIHPVVNRIFSFNQSKEAIQYLFGGQHFGKVVIQVSAEATLPTTKSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL05</accession>
    <name>A0ABR3ZL05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SMC4</name>
        <name evidence="10" type="ORF">Sste5346_002214</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="9">
        <location>
            <begin position="813"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="769"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="949"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1106"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1255"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1572"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="534"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1109"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1121"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1261"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1319"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1572"/>
            <end position="1583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1608" mass="178486" checksum="8F5C7880A138DDBD" modified="2025-10-08" version="1">MSTRPTRRAASRRTAIVESDDEISGDVTINRTINPDDEEDFTPAPTRSPRRPAASSSRRKTIATEGSSTLALKPTRTRRTRASVAASTSTIEPSEIFDPDQAAATVTQSVEADAAEVAPKRAAPRKRKSVAASKQVVVKSETPDVPSLSSLSSLSSIPTPQPSASPEPATEDAENVAPGSAPAPVVAEDASAAEETGDELGADDTVHARDVTMTPLSDITNTSVNERPRTASSTSAADDALAAAKPIRAMDTILEKPMDIVLKSRTMTNIPPVEPAVPKARTVITYLILTNFKSYAGVQEVGPFHASFSSVVGPNGSGKSNVIDSLLFVFGFRASKMRQGKLSALIHNSAQYPNLEYCEVAVHFREVMDLPGGGSEVIPESDLIISRKAFRNNSSTYYINNKTSNFTTVTTLLKDRGVDLDHKRFLILQGEVESIAQMKAKAGNEHEDGLLEYLEDIIGTSKYKTPIEEAATEVETLNDICMEKSGRVQHVEKEKSSLEDKKEKAIAFIRDENELAMKQSALYQIYTSECHDNVAVTEEAISQMQAELDAELEKHHGGEQDIKLLEKQFAKGSKKCDAHEKQTQELIKEMTKFDQERVKFEEKRKFLTDKRKKLDKAINNAEKSAAEATETIEQCTEEIQTRSEEIAQLEEQIKEEEGDLASIRDSLKGKTQAFSDQIATKQKSLEPWKDKLNQTQSAIAVAESELAILQEKANAGATALEEMEAKISSIEEGRDAKAEELKTAQVEKARLEKEAKKVEAELESLAQQEPKLRAQLSNARQKADEARSSLSQTQTQGNVLTALMRMKESGRIEGFHGRLGNLGTIDQKYDVAISTACPSLDNFVTDTVEAGQQCIEYLRKTNLGRGNFICLDKLRTRDLAPIRTPEDAPRLFDLIRAKDDRFRPAFYHALQDTLVATDLAQANRIAYGAKRWRVVTLDGELIDKSGTMSGGGSTVKKGLMSSKLTPDTSKEQVAKLEVDRDALEQRFAEFQDRQRELEGRLRFLRDQIPQLETQMQKNNLEIESAAKNLADAQRRIKELSKEHQPSQSDDNRIAVLEKEIASLNKTVEKLHGETASVEEEIKELQDKIMEVGGEKLRAQRAKIDATKEQLASNNEETSNAEVRKAKAEKQKTKLEKDHAKATKEYEAATRDLEALEAEIESQDENAESLKAAVEEAQEDLLLKKQVLAELKAELDEKMTALNTTRAVEIEMRNKLEENQKVLSDNHQRLHYWENKLSKLRLHDINDLEYSKPVTIKKEPVEDAEGEAAEGEESAEGTEGSAAETEETESSGEAPSSEGEAEEGDITITQAAPVPRRTDSNTPPLTFSQYSKDELADMDKAVLKSEIATLEEKTQNTNVDLGVLAEYRRRVEEHAARSSDLATAVLQRDTAKKRCDDLRRLRLEGFMEGFSTISLRLKEMYQMITMGGNAELELVDSLDPFSEGILFSVMPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQFIVISLRNNMFELAARLVGVYKVNHMTKSVTIENQDYIVRQRSQQQAQAMRQQQLRQQQQAAAQQQAQHDVTVAQTPVRPQTQMQIGQLASPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLP3</accession>
    <name>A0ABR3ZLP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002189</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF10">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="185"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="721" mass="79719" checksum="337C770D6828CD7A" modified="2025-10-08" version="1">MHIFPMESQAGSDYYSFDGLDFLLDANPLPMPTFQFTSVVTTEQPVPFFSPPSDNDTDMDDGEQAIEATENQQNQQNPIRDGDRAGSFSQLGSRLPSLQPEDKNEDNVEEQDAGSKDDLSRTQTNFDPNYHTIDDIHLPDLPSKHISDITSEDRHFLQKAIGPFFSAIPPGFVLPTRLSLGRYIRAYADGFHEHLPFLHIPSMRIGKDGCSVELVLAMAAVGAQYCFEAEQGLGLFHAARAISIERIRRRDARVARSEPLPSGPLGLATTSPEAMPSSEDLMQSGQALLLLMAMATWARHKEILREALAIQSILASIVRDDGLSDENGKTDIHGSIRGPATNSAWHAWARRESVLRTKYIVYCFFNLHCIVYDIPPLILNSEIYMRLPCNTASFKASTAAQWKMAAQREAQTRQSPVQFQDAVRGLFSGDAARNQHQAHSALGNYVLIHAIVQHIFFVRQSARCRFDTDSELTAEEAAPLDQAVRNWQAAWKHSPESSVNPLDPNGPVAFNSTALLRLAYIRLNMDTGPGRALGTRDPVQIAHALRNTPPLTLHRTSAHTSSKLIRALLHAAHALSIPVKIGIRLVAKTQTFTWSIQHSLCSLECALILGKWLEAMAALGSTPNPPVTAEEERILSLVHTVLDETEYRLPRHSSTNSESSEGLGDAEDCGAYEIMNLPNRAKRLNAGVLRVWAAIFRGSQTWDIVEVIGNALAMYADLVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMF3</accession>
    <name>A0ABR3ZMF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002404</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="225"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="419" mass="46195" checksum="8AE555AA609FB4A4" modified="2025-10-08" version="1">MNLDFPMPWSHDLSLMDWISPQSLEPPADNNFNMTFAYDTPSMMFGTGVPQFQLTPVSESPQVTCDDGNASAVQGIISQSQAMPAIQTWPQPTNGGDVSQVASNQIQADPNPQQTLQDTRAAITHQWITEWDPTSQDNIVAFPDMSRVTRDILEAEELAQVESIGSACYSEIARCLRRHAGLATGGTNATNSGSGATGGGGSRPHYRDFTNANLPPFRAMNCFVQLYFEHFQGIFPMLHQGTFHPAHQPWQLVLAVAAIGCRYSKLPGTAQFADALQELLRRAIADTIESDNSVARATWMCQCIILNSLGMSYSGNKRLLEVAEIKRNTPATMVRRIGCLSQQYSDYRAHQAARGQYDGQAAVPPASTDLDREWKAWVAEEAFRRLGFCAFVGSSRFTTWWCQNANSHDSSPTRKSPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNP8</accession>
    <name>A0ABR3ZNP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional coactivator HFI1/ADA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001571</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024738">
        <property type="entry name" value="Hfi1/Tada1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12767">
        <property type="entry name" value="SAGA-Tad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="53902" checksum="9E7DE69656150772" modified="2025-10-08" version="1">MPDINPADLSRPAVSLSTPILSNKSITVSSSLKPAKAGQSIPPRIELEQAYTSLRMAVGNEQWKIYKTATTQFFIGRLNQAEYTHIIDPILYSPTGEREHLHNQLISAIYGNVTRDLPDPGLAPWVSANDKPSSGLGSKPSGNDANERRIKGEVMLLPSKDRRRIKDIVNNEKFDPYDALASVFTDQQRMKVPRPMDAPPASASGGINRMNLDLEIRKRFAQPLAVESGEFPDTSNIESRMLPFCYEAGLVSGHVSDAAQFMSIATETFVKEVLSSVFSRTRSDGPGEYGSAGFGGSNWVQTRKYRRQLAREEERSLHGEIHRDKMGLLPIEAKKASERGPLGVAEFRLALEMGDCGLTQFPIVGHSLMSSYREGELENWDDFTWMEGLDPTQDDDSLESTLPSLLPAATVNGTVPGTGTGDAAGGAPGAPGGTAMVKTGSSAGAASAVEGIHLKTGQPNGVDYSDMMDIDDNEELSWEGADMGDGDLLSGVLESVLAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNY3</accession>
    <name>A0ABR3ZNY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UTP23 sensor motif region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001663</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09865">
        <property type="entry name" value="PIN_ScUtp23p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="8">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="306" mass="33894" checksum="8015CADD07F58021" modified="2025-10-08" version="1">MRAKRSKQYKKLIQQYQLHHGFREPYQVLVDGDLVRDAERFTMDLQAGLERTLHGKVKIMITQCCIRHLYSMPKEPGINRAIDLAKTFERRRCGHRPDDFEEALSTLDCLTHVVDKDGRGENKHRYVVATQDQSVRRYMRTVSGVPLIYINRSVMIMEPMSEMTAKVGASAERAKFRSELRKSAAAAGEKRKRDDADNGGDGDKDGSDDDNDDDDANGDDKPQTEAQAEEKKKKKKAFGVKGPNPLSMKKKKKTGPPGSGAGAAASKPKTTDDGAPKKKRIRKHKAQPAGESSASAVPAAEATADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP05</accession>
    <name>A0ABR3ZP05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATP4</name>
        <name evidence="10" type="ORF">Sste5346_001529</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0138">CF(0)</keyword>
    <keyword evidence="3 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="248" mass="26652" checksum="4380BEC912D7D09B" modified="2025-10-08" version="1">MASRLARNAAGLARLRPTLSARPALPTLATSVRMSSTSSSSSSSVPAEDPKAKASSILDALPGNSLISKSAILSSAAGLSIYALSNEYYVVNEETVVAFCLISVWAGLIKYGGPLYKSWAEGQNEKIRGILNAARADHSQAVKTRIEDVQQMSSVVDITKSLFAVSKETATLEAQAFELEQKTAIAAEAKSVLESWVRYESQVKQRQQRELAESVIAKVKKELESPKSLQQILQQAVADVEKIAAAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPA5</accession>
    <name>A0ABR3ZPA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I Iterative PKS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="385"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="1311"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1674"/>
            <end position="1751"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1806"/>
            <end position="1883"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1311"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1470"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1755"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1759"/>
            <end position="1771"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="1343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="1531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2194" mass="237021" checksum="FFC4A12384A62BFF" modified="2025-10-08" version="1">MADRLAFLLFGDQSLDTYAFLSGFYREENQGILATAFLNQASQALWREIEGLGRLERAKLPLFKTLQQLNERYHAQELKHPGLDGALLCITQLAHYIDHAEKNWEDVTRHDHTFLVGLCSGLFAAAAIASTPSLSALVPVAVQAVLMSFRTGLHVSSLADRLCPPLAKSESWTYIYPSQREEDVRRILSEFCSSNAIPPAAAVYISAVSSSNVAVSGPPSTLKALAASGKLGRSASIPVHGPYHASHLHADADVKKILRLDDATVSDALFKTKPRSAVMSCATGTWLSETTTEALFEAAVYEILNEPLLFNRVLDGCLDLARDYTSGDCVVIPFGPTQNANTLANLLRSKTELKVTLRSSPEFASTASSITAKPSKIGNHGSSSRGKLAIVGMAGRFPDAASHEKLWELLAKGLDVHRVVPADRFPAATHVDPTGKAINTSHTPYGCWIENPGFFDPRFFNMSPREALQTDPMQRMAIATAFEALEMSGYVPNRTPSTRLDRIGTFYGQTSDDWREINAAQEVDTYFITGGVRAFGPGRINYHFGFSGPSLNIDTACSSSAAAMNVACTALWARDCDTAIVGGLSCMTNSDIFAGLSRGQFLSKKGPCATFDDGADGYCRGDGCASVIVKRLEDAEADGDNILAVILGTATNHSADAISITHPHGPTQSILSSAILDEAGVDPLDVDYVEMHGTGTQAGDGTEMLSVTNVFAPADRKRSADRPLYLGAVKANVGHGEAASGVTALVKVLLMLQKNQIPPHVGIKQEINKGFPKDLSDRNVNIAFHMTPFRRTDGKPRRVFINNFSAAGGNTGLLLEDAPRRVPATADPRSTHVITVTGKSKSAMIHNAERLVSWIDEHPDTPVADVAYTTTARRIQHYWRMNVTATDLAEAKQALQVRLKGNFVPVLPEQPKVAFMFTGQGSHYAALGKEFFAHAAVFRNSIDEFNQIAKIHGFPSFLPLIDGSEPDVTKLSPVVVQLGLACFEMALARLWISWGIKPAAVLGHSLGEYAALNIAGVLSASDTIYLVGARARLLVEKCTAGTHTMLAVQGSLSTVTDALGARASSVNVACINGPRETVLSGDAAEMAEIAQQLGIAGFKCTQLKVPFAFHSAQVDPILDDFEKLARAVTFNAPTVPIISPLLGKLIAVGDSDNNSAPVNPAYLRNHAREAVNFLGGLVSAQQSGAIDEKTVWLEVGPHPVCANMVKAAFGATTIAVPTLRRNEATYKTLSASLCTLHSAGLNVDWNEMHNDFRASTRLLDLPTYAFDNKNYWLQYEGDWSLIKNRFAKMLPAASSAAIEPAKPTLSTSSVHKVVCEEVNGNTVTLDTESDMCRADMRLALEGHLVNNTPLCPSTLYADMAMTISDYMYRLAKPDAKDKVPTNISDMEVVKTLIFDDSTGSHILRVSATAHVDKGYATLSFHTGEGGKKTEHATCRVLYGDAEQWANEFERVNYLIRARIDALKAGEEKGTASKIGRGIAYKLFTALVDYAPRYRGMEEVILDSATCEATATVRFQTSEKDGNYFFNPFWIDSMCHISGFIVNATDAVDSREQVYISHGWGSLRFIEKPDATKTYHSYIRMQPVKGTKMFSGDAYVFDGDRIIGVCGDVRFAAIPRKVLNLVLPPRGVAGAPAPASTAAPARKAVAAAPSASSAAPAKAKNTKVVTHANIGKVNQKLTSVITQVFDILAKEIGVSNDELVDNVAFGDLGVDSLMSLTVSGRIREELDVDLHSNAFVDYPTIGAFKKYLAQFETNRKDSEGASLEDSGISSSDSETDGMKSDSELTTPMEESENGSVKDGGECAPAAGDVSALQKAVRDTIAEEMQVEVDEIIAAPDLANLGMDSLMSLQILGTLREKTGLNIPSDLFVSNPSLKDIERCLGIEARPPPAPKRVVVVEAPAPAATQTVQRGQEIRLEPADPIEKLPPPTKIIDHYPHRKASSVLLQGSHRTATHNLFMVPDGSGSATSYTEISEIGADWAVWGLFSPFMKTPEEYNCGVYGMAAKFIDEIKRRQPVGPYSLAGWSAGGVIAYEIVNQLTKAGETVDNIVFIDSPCPITIEPLPKGLHAWFASIGLLGDGDADKVPSWLLPHFAASVTALSNYTAEPIPMTKCPKITVIWCEDGVCHLPTDPRPQPYPEGHALFLLDNRSDFGPNRWDEYLDPRKMTIRHMPGNHFSMMHGDLAKQLGALMREGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQS3</accession>
    <name>A0ABR3ZQS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein-sorting-associated protein 33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS33</name>
        <name evidence="4" type="ORF">Sste5346_000675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043155">
        <property type="entry name" value="VPS33_dom3b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="668" mass="73443" checksum="E37DD2D41146159B" modified="2025-10-08" version="1">MAPHADFDTGEVREKARRDLLYLLEAVRGKKNLVIEKSLAGPIGTVAKVSTLQDYGVDKFFFLENGNTDTSQRNVIFVARGECGRHAQNIADQIRRLQRESQTGHDFHIFWVPRRTLVTDSILEEAGVLGDVSISELPLYFFPLEHDVLSLELEDTFQDLYLTKDPTSSFILAKALMGIQQRHGLFPRIIGKGDNAKRVAELLGRFRQELLAGEDVSEANKIGPTPSSTTESVIIIDREVDLVTPLLTQLTYEGLIDELYGIQNSQTDVDSTIVGAAPASTNAGGTQSASSSTGGASAGVSSGARKRKIQLDSSDKLYEELRDANFAIVGSLLNKVARRLQSDYEGRHSTRTTAELRDFVQKLPGYQAEQASLKIHAGLVEEIYKYTRSDEFSSLLEVQQNLAAGADPSAQFDAIEELIARDTPLNQVLRLLCIYSCISGGIKPKEYDQFRRLILEGYGYQHLLTLQNLETLQMFLPRSSPLAGMIPMAGSAGAAGTKTNYTFLRKQLRLIVDEVSEQDPNDIAYVYSGYAPLSVRLVQCILQKQYLLTFTKGNGITSGSQGWRGFDEAVKHVRGQTFDILQKGEDKAVKARALLSGSGNKKTVFVVFVGGITFTEIAALRFIARKEEGRRRIVICTTSIVSGNKMMAAAVENGSFKRDTGLDASAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRS7</accession>
    <name>A0ABR3ZRS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Origin recognition complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ORC2</name>
        <name evidence="8" type="ORF">Sste5346_000409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02178">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="6">
        <location>
            <begin position="426"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="7">
        <location>
            <begin position="717"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="296"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="689"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="786" mass="83644" checksum="F13834511603E81B" modified="2025-10-08" version="1">MARSTTKRNSSRDGAVDATTAAVTGHRQTSPFNENHIAEQLNTPTKKRTPARSTNGTNGPGDGLDVFENTGRDEEGLSVLSANKANGARKTRRRAAAATVSYGGMDGDDEGNDDDETEEEVVTEIAQAKTNGAGDGGPVSPIAAGFELDSAMEEEPAAGAPMETPRKRGRPAKARFADRFDSPDGPIERTPTSKRRKTDFATPTKSTPIKARGGIAAPTPNTKRTLADRSARKKSTRALIDRMVAGGDDDDEDEEAINDAILDAEFEDDEEEEMEGPAVTNGLELGRDIPVVQEVAESTPAPEAPTPRKRGRPPKAKGAAPTPAKPAPVVIGPDGQPIVKRGRGRPRKVDGAGPSTSTSAAAARDVTPPRDLPAHEHYFFQNRAGAGIKTSNNTLAALRLLTYDEYFRLRDGGTGNVVNRHEKQIGYLEELHSQSFAQWAFELSQGFGVCLYGYGSKQRVLRAFATALHKGIRDHGAHKIVMVNTSTAGAAASTTTTAPTNGASMGLTASAAASTLKDIMLVLAAAASGVVSHGKDAPPKLPSGLAAAERIVLSLLDKADKTDSAFQVTLIINGIDSPSLRRPAAQATLARLAAHHSVRLLCAADTPSFALLWDGAARSQQNFVFHDATTFRPLAGLDTVDEVHALLGRRIRRVGGKDGAAFVLRSLPENARTLFQLLVGEALAADEGQKSGGGGGFGYDDEDDYGEDGEDRDGGAAESVALEYRMLYNKAVEEFICSSEMAFRTLLKEFHDHQMVTSRKDAFGTEMLSLPFRRDELEALLEDLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRS9</accession>
    <name>A0ABR3ZRS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09397">
        <property type="entry name" value="LIM1_UF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24207">
        <property type="entry name" value="ZYX102 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24207:SF2">
        <property type="entry name" value="ZYX102 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="619"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="683"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="750"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="325"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="435"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="782"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="830" mass="88967" checksum="4B6FCF6951350339" modified="2025-10-08" version="1">MDRPASILPTIKCSSCSQEIEISMMGEHICGKAAEEVTPPPPANFDQFMSYGNKSISSNNNSSRDNYNDNYGSRNNSNSNYGYSSRDQDRSNRLPPQVDTSAANRSYYRAGQLTPVSNSSGSQSVSPKTPVGMMMGGLRTGGLGGGRGNDRNGNDRNMSDRAPAGDYFEPKIAGEFDSPASAYGSSTQPRRPGGYGGLDDDAYPPPSSSPKRQPATNLLQRMNSIAPGPFDTNNSGAGAGGLGRKPTNARNAFPRAANNSDYSRENMEDRSRTLDDDDFQPPSFNRAGTFPRLNESAEPPSRTPSAPGPRPERRRQANNDGYGNMGPANNMNNMNNTYSNNNASSYGSNSPPSNSMRRPSMGPDTSRPPPPRTSLLRPRTSGRDGSSMDSNSPSIPQINLAAEFGIGNPYHSASDSMSSTVSSVMSRPGGNLPFSSSQSSFSSSASSFTTSSSSNSLNNSNNYYNNNSSRDQPREVPREQPRKPSNAANMADFDSLMNDLQSLNPAEERKKERRDERPAQNDRGRNGGYGGFGASSNTATSNSRTSPDRRPQSRGRNGMRDEMDNGYGNNLRREPSRARDQSVGANRGNNGGWSRSAGAAPQMPAMPIIPVLPPMPSRGNCKACGDLITGKSVSSADGRLTGRYHKACFVCTTCSEPFSSSTFYVHNDKPYCERHYHAVNGSLCGSCGNGIEGSYLADEADSKFHPTCFVCADCRLPLEDGYFEVAGAVYCERDAWKRVQQSYLSQAPQVPQISTPTSARGAGMGNNLTVPRGAPGGGLPSGPGVSRRPSVGLPNPNQLGSAARPFGLPSGNRLGPRPRMEKRMTRLGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS29</accession>
    <name>A0ABR3ZS29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="12">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SCH9</name>
        <name evidence="12" type="ORF">Sste5346_000806</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05586">
        <property type="entry name" value="STKc_Sck1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="307"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="512"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="11">
        <location>
            <begin position="774"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="256"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="864"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="174"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="924" mass="99938" checksum="EE897655CF2E62E4" modified="2025-10-08" version="1">MAQQQSKIEDDESQTQIQSRQPDETQTEPLPSAPPPPPQPPQEQTPATEDTALSSESLAAAAPSSLHPYPTPPASIRGVVGTGSGGSGAGAAGVAKESEEEASTKKDGAGGAAAGAAGSTPNPWDAPWTFRSHKKSISDVPEARGRQESLSSSTPLAGVVTPSSVLARHFSIPSIPSLATPSSTSTSSNTPASTRSPSIAPGPGSGPRASTAPDTPVCVGSPAADASLAPAAAVAAAAVLRSASVGQLKKLTTMTRIKSGQSTPTRSLSTAQPQAAEARATPAPTSAGNESARTTMSRGGDDSSRSRAASITPTPQGAQAPAPKGKLTIKIVEARGLRRTRDPYVVAVFQRSELISGGPRSSDNDDEAVLPGVAISSIPIQRQASDNGRPMAIPMRSRQSSNTSTADYGAFRNRNARRSFTNPKWDAEAVFDVVDSNMLVDISVYDHSQSGEEFLGHVDFQANSSEKDGPVRGWFPLRGHADTMAENTPTGEVYVEAFYQRTERKHYGPDDFEILRLIGKGTFGQVYQVRKKDTKRIYAMKVLSKKKIVQKKEVAHTVGERNILVRTATSDSPFIVGLKFSFQTPSDLYLVTDYMSGGELFWHLQKEGRFEEGRAKFYIAELILAIEHLHNNNIVYRDLKPENILLDANGHIALCDFGLSKANLTKNDTTNTFCGTTEYLAPEVLLDEAGYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPKDTLSAEGRSFVKGLLNRNPKHRLGATKDAAELMEHPFFRDIDWDALSRKLITPPFKPKLKSDTDVSYFDPIFTDAMDKSGSLNERAAALARGIATSTPLSPSMQANFQGFTFVDESALEDNMRGRPSYNNNDFDDDMHDAGYHNSHGGRKDDNDWDDINDIDPRNANRMSGIVRTTNDEHMFGDTHFDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH1</accession>
    <name>A0ABR3ZSH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="131" mass="15485" checksum="B81FE79E3804B623" modified="2025-10-08" version="1">MPHHNARPPGPQHQNHNQRRNNRRRRARRQRYRVVQQAQPPRPPPPSSPSPPPWSLSYVDVDEDFDNFPYLDLEEAFEPWWRAVRTYLHCNPFLRYADLDTSNMTYDEAKMEICGIPPEDTSGPQPPYPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSH8</accession>
    <name>A0ABR3ZSH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin-remodeling complex subunit ies6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IES6</name>
        <name evidence="7" type="ORF">Sste5346_000431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="6">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="226" mass="23779" checksum="95D5FBB0528A925B" modified="2025-10-08" version="1">MSNQTPEQIAAHAAHVELVEQRDIHSIHKTFRNPSWKPNQRRNKNVKTILGDVSRREASALATPQENNSGVNTPRASRNSAAAVAAAKAEDDGLSTSGSSTPAGATTGNSGGLPPNLAQANRSLSKLVLEKSLRPPAGGAGGAMGAAALTAVGASAPSVTYTNVESAPSLAPQKRYCDITGLSAPYNDPKTRLRYHNMEVFGAIRNFQQGVAEQYLEMRGAHTVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSU4</accession>
    <name>A0ABR3ZSU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF28">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="327" mass="35923" checksum="533ADF5173C63BDF" modified="2025-10-08" version="1">MSKLIVIIGATGGQGGSVLKTFLSDPEYRVRGITRNPDSGKSQDLKRQGVEVVKADIGDEASLDKAFEGAYAIFAITDYYETFFSKGKDVAMETEFQNGCNLARAASRVPTLRRYIWSTLPFTSHFSGGQAIVPHFEGKARVDQYIKDNLPGLLKKATFAIFGIFSDNLLAYSIFKPIWLESAKKWVQFWPAPPEAPFHSLADHKVNSGVFVHAIISNDTLEGGTYVTCIVEDLTLASALEIWGRASGKAPEPGSTAVVTIPVEQYATLWGAMGEEQASQWIFFSYMQSLGVTSLPGVVDGLSLLSEEEKKSLETTEQSWTKIQDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSU6</accession>
    <name>A0ABR3ZSU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1062" mass="117899" checksum="E1F146A921FF99F4" modified="2025-10-08" version="1">MVMSREAPVISTGAAITGKSHKKNTQEAAAAALQQMAHEKADARLPDTAKYLGFNAVQNKMLKIRAHTLHMALATRFNSDILAPDRKQVLDELLNGRDPENDRPWNLSLLLAEGSQGLILHTLLDPNQFLEDASMYSFCRLRAFISLLLEIEPSMLLEFDKSRRTPLHCLIFSAASEEDEAASSKLLNASKEAIITFMCTKDGFDSRFSRLAKQGKQGKLERQGIESRHIERRQRPAPAPAPTYHNDSENDSADEQTANTCAVYGGTCAGQNNLGMLCCIRDCGAAMEDALASLQELSSMDSGQLTFHAVHAAIEEDIAFPPAVVEALKPCFDIVDSFGRTCLHLAVSMPFTNTKIQWAKSLARMCPGLLAESCEVYVTDSKKKKVTPLQYLAEQRLLDPMPRQRMIKVQNYRFGQDDPMAILDIPPLSTTMDAKLAALEDDLKLHCLAANEDSELCRSYMYTETNEKEIDFPLRDVTVSKKTLDSLCQHFRPDRQLKSVSIENVKIEWDQTSKAYLDTQDWGCAGNSDLYLVFNWLKQTQSVRKVFQVSVNDFDDQTPGSLWRRHSDKAIVECLKGLDVETWDWQRPDIPCSAIQEAAGDSVKTLYLYSSGLDAVLESWASPSGLPRLKKLERIYLCAGQGLESREHAKKSATNFKATIEKNYSEVNGRSLEAVEFAMLQTPEQRALDDRNSSASANEHEANEWLHSMDQFAAFMDQIGNGNSKVPIKVALIDDGVKSSYRGLDDNILCGQSWPIPRTTQETTKVPRVVMSPKYNSSQTGHGTIMAWYIRRMCPRVKLCVAKLDPVVPGLPTVEDKVTFTVDSVIKSLGVAIRKAIDANILIFCANPDKGAEYANNLTYPYHLEKERIFCIGAAGRNGKRWDWIDAKDKSCTYLLPGVDLDIHMETKQPMQPVFVQPSPLITNERPIVGRTLRERSKQSGSSLACALAAGLAAMILHCSRVSGASHKQIDYLRTYDGMKSALDSLYPDGGASASAAGEGQWLPVSSLPSGRSYAHISSSDKKLAVLEDRVERFLENMPDDYIVTVPSNGRVTRTSTMNGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT28</accession>
    <name>A0ABR3ZT28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="480" mass="52404" checksum="7BC4B95C3E2AFD19" modified="2025-10-08" version="1">MSRQSIRNVLRTPGNALQGNVALNCQQRASLSCLSSAARPRSSTTASPLSTSSASATAQRRSTTCASILSPTPAWRPLPSSCQGQVRLLSATAPLNFDAITFRPSSSPELEDLLDNIRNKIILLSYLTELERRKIFDAKYARKLRSDPITREINGEIIRFSHMDLFNDIPKARLATVRAVSLMTTREDFLNLPRLLEGMHRAGRRMHPSDYARIARRAGERNCIIAVIECAKQVHSTGFRLENSEVLAEIFLSLQLKAAESGWDETETRQALNWAEQVVDLLEHPDHGRLPARPPRGHKGNVPADAVVPPQAPLPVYPLHRDPQVLAGRLHLAAAVADRFSANGADTDGKVSRYATELVQLWPAGKGFRALHPEGSYGRRGEMYYLTIDNKFLSVASPLLRGLDTAIKVLGGSQGDSAALVSELQARRDTLAVEVNATLASSPDRRGAIIYNKFFGEEGSGNTNTTTTTITEEAGAAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTQ7</accession>
    <name>A0ABR3ZTQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cation chloride cotransporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000402</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="23"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="8">
        <location>
            <begin position="499"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="610"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="835"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="886"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="953"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1097"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="907"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="919"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="955"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="998"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1063"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1113"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1212" mass="132890" checksum="8DABF14AA5927C18" modified="2025-10-08" version="1">MDRVNHDHGAKKHKLGVVSGVYVPVCLSILSILMFLRFGSILGQIGLLGMLGLFVVSYLVDFVTTLSLSAVASNGEVKGGGTYYLISRSLGPEFGGSIGLLFYLSQVLNTALNVVGLIDCIDLSFDSLVPHGYWWGYFSQTVVLVVCTLLCLAGSALFAKASNGLLVVLAFSTLSIPLSVLVRKPFADPVSGVEFTGVSLATLRSNLLPHSGEDFSFRGLDTFRDLFGILFPATSGIFAGASMSGDLRNPSKSIPTGTLWAMGSTLALYLIVIMSLASSTTHMSLLTQPNIIKETSLWAPIILAGECAVTFFSALMGLIGASKLMQALGRDKLLPGLSVFAWGTEKHDEPLLALLATYAIAQLALFANLNQIATFISMGYMVTFFVMNLACFLLKIGSAPNFRPAFKFFSWQTAFLGSVMSAAAMFFIDETYATSSVILLVMLFLLIHYLCPPKRWGDVSQNLIYHQVRKYLLRLKPEHIKFWRPQIILLTNDPRRQTRLIQFCNSMKKGGLYILGHVIVTDDFTTGVLEAKLQQTLWSQYITEYSRIKAFVQLTMSPSITWGARNLILASGLGGMRPNIAVLGFYNMDELRMAHPLLRIPELPLSAATSMRNGRKGGASTGLSSSGNNPTVVRPRRRRGDTTSRILEGVLPTDVIKTEGMMKATEYLTILEDLALRHRINVAVAKGFHSLETPRADSTNTKKYIDLWPIQMSAELEADGKSVLTTNFDTYTLILQLGYILHTVPAWKRVYSLRVMVFVEYENEVEEERGRVEALLEKLRISAEVHVFWLASGDLTTYEAIVQGEADPSTEKIVDDVLGDSLWWADLQEIRGKVIPRRNGGSDEGPSSWKDDVRKRRPSIAHIQELQKHQTVSALARLGVSMGIRTQNLAGQRPTHPRYNRDDNGDDYSSAISDSSSTSDEDDFDTTDFNDVESAASEGDIDDVDDEADAIPLAPSSSMRFSSNIVPETRITNPEDSGRTIMFAETSASDRPERPPFSRTNSRQSRVSLADSMTKKRPKTTPRPSVSFAEPERDPSAQQEQRPHRPLLSRHSSTPVVQRAPFTEDDLGDENGENGGGEVRIGIAGLLADYKARRRVNSSGSGEIGDGDDSNDDSNGSGSSYSTQDLALSFNDLPSRAQHLILNELMRQHSGESGDLTGGAAVLFTTLPIPDEGTHRDETASVQYLSDVELLCQGLPPVLMILSNNMTVTVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU81</accession>
    <name>A0ABR3ZU81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitotic exit network component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MOB1</name>
        <name evidence="2" type="ORF">Sste5346_000256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="219" mass="25171" checksum="8AD9AFC175AE24F4" modified="2025-10-08" version="1">MASLLTTVNARTRNQFRPRAPGKGGNTSYQLRQYAEATLGGGSLRKVVKLPEGEDENEWLAVNMVDFYNQINLLYGAITEFCSPQSCPEMKATDEFEYLWQDSDNYKKPTKMPAPAYIEQLMAWVQSTIDNEAVMPSRIGVPFPKNFPSLMKQIFKRMYRVYAHIYCHHYPVIRELGLEPHLNTSFKQYVLFIDEHNLASGKDFWGPLGDLVESMLRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH08</accession>
    <name>A0ABR3YH08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_010197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="94"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="491" mass="52143" checksum="8C7162207402015F" modified="2025-10-08" version="1">MTDKETKVAIPGNGTDTDDNTLAAPSISAAAIAEGDASGIRTKESDPEKNNNAPVSDDSDDDEDVVEGVPPGGADLAQTASFSFQDVPDGGWQAWLVVFGAWCTSFCSFGWINSVGIFQEYYQTGPLSTYSSSTISWIPSLQIFFIMAMGPIVGRLFDAYGPRYVILAGSLLDVFGLMMASISSEYYQFLLSQGVCSAIGVSAIFQPALSCIPGWFNKRRGIAYGIVSTGSSLGGVIFPIMVSRLIDSVGYGWAMRACAFLILGLLIIANLTVHSRFHAHPNFKRGEGLSRQQMVAPFVEPGFALLLIGMFFLTFGIFVPITYIPVGALATGNVSASLAQYTVSILNALSLFGRLLSGWASDRIGKYNAFILSCYCAGIVVLALWIPGSSKSAIIAFASLFGFFSGAYVSLIASLVAQVSPHKEMGYRTGMVFLVASIPGLVTSPIAGAILAHNDNWVGVKVFAGVLLLVGSTIIAFARVKYAGFSPMTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHB3</accession>
    <name>A0ABR3YHB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000114">
        <property type="protein sequence ID" value="KAL1887597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF97">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="326" mass="35116" checksum="A23660003B20B06F" modified="2025-10-08" version="1">MVVQHAGLLGGLAEHDFGQVVAELLANGAALAKGRHHGLGITVAWAGVILVFLPDSPHKGRIFSEYERAVFVWRVAQDKRGVKSPKIRMNQIWETLIDPKTWLLCLSSAALGILNGGVVNFKSALIAGFGFAGQEANLLGMPSGAIQIVSCVLFGMLARLKNIKGVAMIVSCIPGVVGLIGILKISHNPKYKYSLVACTWLQACIAAPVAISWSLPVVNVAGHTKRSCTLGLIFIFFAAGMIGGPHLFIASEALRYPTAIIGLLSSYGAAMLLQAAYTALCYFQNKARDEKYGRPTEADVRAREDAALRGFEDQTDMENKEFRFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHI4</accession>
    <name>A0ABR3YHI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-glucuronidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF3">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="1">
        <location>
            <begin position="237"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="344" mass="36947" checksum="625D2DE7E322E1F5" modified="2025-10-08" version="1">MSRTVFYPYTGEAEDSLAISPMLIVQEYGGTSAWTPAVEALNQVQWQLAIEPTLDKKRIFQAGAYYLPPTYGYNAAELLPVASSNGSLEYFGSFSHHNYPQTASAKANSSAPVLDELMSHVNTSDNVALYAADTAAADKYGVEYVFGETNSVSGGGSSDISPTFGAGLWVLDYVLRATSSNITKLNFHFQSYGTSYYIWWDEESIRSPYYGGFVATDALAGESYITALDDGTSNYAAYAIYSADKTLSKVVLINTDYFDGAGTRSSHSFIISGLTSKSISAKRLTAASALSRQDEGDAPTYAGQSFSNNGNCALTGKKEMEQVSVSSGKATLKLYASEALVITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHV6</accession>
    <name>A0ABR3YHV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020301">
        <property type="entry name" value="Mrx7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10906">
        <property type="entry name" value="Mrx7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="96" mass="10595" checksum="62184248BF7E9C4B" modified="2025-10-08" version="1">MAPWSLIVRAVMAMEDIFVQKLLASPGFHGIVRRIHRGVHEARYGRDPNEPLRKGEATADPNKGSGGGGSRGFLSHFVEELQNQARGTTTKDVRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHY0</accession>
    <name>A0ABR3YHY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481:SF0">
        <property type="entry name" value="LD23870P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481">
        <property type="entry name" value="RIBONUCLEIC ACID BINDING PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="120"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="386" mass="41517" checksum="1EF786B3BC91320F" modified="2025-10-08" version="1">MASRDPSAASSMRSRSRSRSARSISKSRSRSRSRSHSRGRSGRPPFSPRSNRSGSRSISRSRSRSPRSTRSRSRSRTPRDRSDSRGRSVSRSRSRSYSRTRSYSRTPSRSRSRTPPARTAKVVVEKLTTNVNEDHLYEIFGEFGHIVDLDLPISHVSHTNRGTAYILYGNETDAVSAAAHMHEALLDGNIINVSVVLPRRKLTRTPKQAKRGGGGGGRQKKGNEGGGRDGGGGGGGGGGGGGRDGGGGGRRRDRGKNARAFDTYRPRSVSPGGRRSRSPAAGPGKGDGDSAKNTKNRYRSRSPQLDRSHSPAYRSRSWSRSKSRSRSRSPPPPGGGRNNNNGGRHRRRKGRRGGSGRRNREGGGGGGGGGGGGRDNGRQVDAQRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ33</accession>
    <name>A0ABR3YJ33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000120">
        <property type="protein sequence ID" value="KAL1887434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="27850" checksum="BC9B3B26AE715E9D" modified="2025-10-08" version="1">MAGDDVKKAFVFYNYKPNLAAAILFSVLFFIMTFAHVTRMAMKRTWYFVPFVLGCLSRGGAIVEAVGYIGRALSSKEAPDFTKDPYIVQSLLILLGPTLMAATVYMVLGRLVLVLQGEKNAIIKPRWITKVFVTGDVLSFFTQGAGPGLLSAAKIQSDVNKANYIIVGGLAIQILFFGFFIVVTAFFHRRITMILIRSVYRMAEYAQGSAGELQKKEFWLYIFDSLPIIVVTLSSSTVEGDIDMANETSSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJE9</accession>
    <name>A0ABR3YJE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-reducing end beta-L-arabinofuranosidase-like GH127 middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049046">
        <property type="entry name" value="Beta-AFase-like_GH127_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151:SF0">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20736">
        <property type="entry name" value="Glyco_hydro127M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045522098" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle" evidence="2">
        <location>
            <begin position="459"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="719" mass="78702" checksum="5D4EB322B94E79C8" modified="2025-10-08" version="1">MMKILWLILCSLGAVGAALAAAETSQRRAVDSSPSLTALKPFRFQNYAPGTITPTGWLRDQMQLLADGLGGNLFDFYRFVHESSWLGGRHEYSTLNEASPYWFNGIVPLAWGLNDARLKAQAKQYLDYVLDHQQADGWLGPETTPQTRGLWARALLFFGLTQYAEADPTETERIVDAMHRFVVLANAMLKDNYRGLINNATLGDVYDPYEFGTARAQELPVSLMWLYDNYPRNNSELILDTISLMFAGSRKANFDWTTFFVDGIFPTGAAPNPAPGFMHGVNMAEGMRYPAVLYRLTGNESLVTQTANAVSLITTYQSALSGTIIADEFVGGLDPQRGSELCIAVEVMFSYAYLYRFFGVNDYADRTERAAFNALPVALAPDWWSRQYLTQTNQPWIQRLSSDPFFNDNTYSLTYALEPNYPCCTVNHPQGYPKFVTSSYVKDGDDGIAHILLSPTSLTTTVGGKSVSITCNTHYPFSEVLEYTIVAKTAFSFSVRVPGWVAGAATAQVTTAASHGRKTVSTVTMTPDANTGLHLFNVAAGTTTISVTLPMANDIVMREATSEAGVSAPSVGIYHGPLVYALSLDYEETTHLPLNFSTGNETPLEAFDVVPKCRDHFLLPTSNWSYAVDPSTIAFQSLDKASDALTNPIWSNNAPPVFITVNAYPITWSNASGTAAVPPAVNASAVDTSEKTQLKLIPFAAAKLHISQFPIFNASVTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJJ7</accession>
    <name>A0ABR3YJJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="221" mass="24061" checksum="986171D5B890AD89" modified="2025-10-08" version="1">MSTATTSTGPAPAALLAKLLEVNEKQIVPLTAKGVASGSKVFGAAILTRDGLEAHTVATNNERDSPLLHGEINCIQTFFGTPAEGRPATADCVFFATHEPCSLCLSGITWAGFKEFYYLFTYEDSRDLFAIPYDIDILESVFRVPAPGDTPETLADRPLYNKTNKFFTSASLADLVTRIEDPAEREHWASEVARVKALYGQLSETYQEGKKAGAETSSVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJQ6</accession>
    <name>A0ABR3YJQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046618125" evidence="1">
        <location>
            <begin position="19"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="224" mass="25047" checksum="5F1918D1A0C736C8" modified="2025-10-08" version="1">MGLVRTTVFTGLLGTSTAAAYLAARNPVISPLAAADPVWSSSVYKKQNPARNPATQDICIKRVPISKIKPELLKKDGDLALEFCRGLWGGWGYTIQRKYLEYKYRGPETASQLWDPEELQTSNYDKGTQITDHFEVLEKTPTSITVRAGDTPRTRGPRASDGLYIISATVDKPNELVELSVKSVFFSSEGKVEGKKGPMPPWIDELHQWYSRVLNETASWRLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJW9</accession>
    <name>A0ABR3YJW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009767</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="619" mass="69407" checksum="8D472CE5883F5B98" modified="2025-10-08" version="1">MSCSILTHRIRQRKVKCDEARPKCSHCDRLNIQCRWRSMSRSVITSGGGQMSSNSSGSRTPTMDTTLGGSLSPRPEPFPNPSPFHHTQTQAQVQHVQPQVAQQTTTPLFDYTNFSWDGRDTWQQMILDVGREINFDPNATDTDFGPTQAHDLTSLATQAAAIRAAEIPTAHNVSEVASALSDDTSPHTNAELTGRNAADNHRLINYFTHAVTPPILSEVEAQKNWITVRRILTKMAGDSRMVRWAVLAFSNAMLCRHEGSWMASQQNHYENAAAEVALFSSQQELETLTHHSPRREKLLATLFFLSYVDILDAKIEAAHVYLKQAYNIFLQGRKAGFAPIEKQLLLWIRLLDARAVPAGGEGLFLSRDNEELFVQQPSPASFGETVAEGTGTFVGDSDVEDALFQALYQPGIVFFQKVQSFMGHIAKIDQWHRSRGTVEDETDVMRIAAAIASDLRDLYEQRPSLMDYAVAGKLTAPHISAKLAFTITRAFRTYLSNYYASKIHLHRVAYKNFPLTKEAIEALDHIRSLARLIAESLDGEDPLPINMLWPLVMLGTEEKDPVERAWIKTQLLRMEKIAGNARITTQVLDEVQARQDASKMREDIGTVMRSIFNVRFAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK01</accession>
    <name>A0ABR3YK01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Niemann-Pick type C-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NCR1</name>
        <name evidence="14" type="ORF">Sste5346_009432</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045791633" evidence="12">
        <location>
            <begin position="26"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="616"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="653"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="735"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="760"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="853"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1093"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1126"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1155"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1199"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1240"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="13">
        <location>
            <begin position="611"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1299" mass="142491" checksum="5B350F957313F9CA" modified="2025-10-08" version="1">MTRLSRAVAAGGSVALLLLAGLGEAAATTASTGLTAKHEAGRCAIRGQCGKKSIFGADLPCVDNDLATEPDEKLREQLVDLCGPKWKSGPICCDGQQVKALKDNLATANQLISSCPACKDNFYNLFCTFTCSPDQSLFINVTDAAEKNGKLLVTELDQLVSEEYGTGFYNSCKEVKFGPTNSKAMALIGGGAKNYTEFLTFLGKQRLGGSPFQMNFPLSYAEPNMSPRQSVPKKCNDEDPNFRCACIDCPAVCPELPALKKEKACHVGLLPCLSFASILTYSVLSALVILWAGLRFWYTQNRNQGLPLLHDPHGDVDDEDDVEDDEHHAFLYGFIRGSTSNVAAAEEAPTDYVLNIWCNKVFRKLGHWAARFPGISIGCSLLVATVLSLGLFRFKLELDPARLWVSPTSAAAQEKAFFDSSFGPFYRAEQVFLVNDTLPSGPGPVLSQETLLWWMDVEKSIQELKGQEYGVTLNDVCFKPTGSACVVQSVAAYFGNEPSLVDKYWKDTLRSCAQRPVECRPEYGQPLDPESILGQFPNASHADEAHGMTVTWVVNNYAEDTPEVKRAMDWEQALKKRLLEVQKEATARGLRLSFSTEISLEEELNKSTNTDAKIVIISYVIMFLYASIALGSTTLSFGDLFRHFGVFLVESKFGLGFIGVLIVVMSITASIGLFSWAGLKATLIIVDVIPFIVLAVGVDNIFLIVHEFERVNISHRDEEVAERVALALGRMGPSILFSAITETASFALGAFVGMPAVRNFAIYAAGAVFINAILQVTGFVSVLALNQIRVEENRADILFCIPVKSARVHLNDEYSGRYNDSNGYKEGLARESLLQRFIRQRYAPTLLKKSVKAGVLIFFTGLFAAGIALLPYVQLGLDQRVAIPDDSYLIPYFNDLYDYFESGPPVYFVTKDLNATHRLHQQELCSRFPTCQLTSLMGTLEQERKRSNVSYIASPTASWIDDFFLWLNPDFESCCVENGKPCFANRIPPWNVTLSGMPEGDEFVHYLKKFIAAPTTEDCPLGGQASYGQALVIDSEHDTLPATHFRTMHTPLRSQDDFIKAYASARRVASDITRETGVEVFPYSVFYIFFDQYATIVSLSATLLGSAMAIIFAVSWVILGSFMTAAVVTCTVAMTICDIVGAMAIMGVSLNAVSLVNLIICVGISVEFCAHIARAFTFPSALLRHNARTRFPDAREQRAWAALVNVGGSVFSGITLTKLLGVTVLAFTRSKIFEIYYFRVWVALVAFASTHALIFLPVALSVAGGREYLDADGEGGLPADLASRLRDAEDTSDDEDGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK34</accession>
    <name>A0ABR3YK34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Meiotically up-regulated protein Msb1/Mug8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04401">
        <property type="entry name" value="RhoGAP_fMSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037508">
        <property type="entry name" value="Msb1/Mug8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012965">
        <property type="entry name" value="Msb1/Mug8_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28093">
        <property type="entry name" value="MORPHOGENESIS-RELATED PROTEIN MSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28093:SF1">
        <property type="entry name" value="MORPHOGENESIS-RELATED PROTEIN MSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08101">
        <property type="entry name" value="Msb1-Mug8_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meiotically up-regulated protein Msb1/Mug8" evidence="2">
        <location>
            <begin position="47"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="796"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="910"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1104" mass="119108" checksum="350F42885C6F3BA5" modified="2025-10-08" version="1">MPSIFSRLKGKDGPTKVKSKKNGAGQAFASQVPAKPRWEDAYTRKTVEPEEIHELVRLCTEELKARALDIPFLLLPFRPTSDPSAVRTFIRHFFDQNAPLSGELLLQELRMTEPMVISGVVKWCWSRLQGGVVGWDAYELFKIGEQDSHGAHSSFTTFIPLSVDNHARSSIIFSFFDLMSAIAAHGKVNGFGGRKLSRMASWWAFENNDTGNGFEGGYKEWLKAADATSHLFFAYLRSLSPQQGIGSFAVLPMSLQKLLQETEYPPQRPSLLQSSTNKVIMIVDTVSPTPFSLLRRGSHFQYRDDDRALREFSDYEDPVQALTDECRRVLKAISAANQTQAVSSSKHSTSLRDASWSRFEDIGFGSVLEEEDEEDDSAKDLANRRNRGLRTTPASGGDGLARPTTPSWADFLSSGFVDDGPNSPTNMLLPPDKVLPPIDTQIRQRSSQSHRPRLETERTLEPGELASISRFDLDDSFWWVWMTSLAPEETPERKSAFGRCAVIETRIRTGRWLVMEEIVKGAAAEPDAGAYIAEKKGFFSWTRRNKGISRSKSTGKQALDRGQHGLLAPNNTLGVSKTSIVADQQAKIQAAAQRLHERQRAEEREQAGSTLAKRGRVENASHEKTTSIMTIQPVIASEASSAMKWASKYDKEAIRDAYLSNSNAGRGNPASMSTPAVHTNGINSSTNGHEKSHPVLDSTRKPVAASPAPVQQPIVAPAPAPAPAPAPVASAAPPASSASLAILPAPARNEDSLDLSEKAVRVADSPTSIHPAERQEESGRTSPPVPPKDNQASLNATRAAIVPPTPTPAVETSPEGKKALKKLHKDGKEEKASLPPSSSTGGLRKLFGRKNRQSKLPDNAAAGVNALLAADAKKNAAPKAAAPAQKPASIASTAPPAAPKATPAPPAPVAPVAAPISAPEPTVETEQAAEPPRTPTVPEPIYAVSNGSESRIGTADAQDAAKEFSRFDQGPLTDQPAFIPEDSDNEADEAVPPPIARQRSPVSPEPLASVPATEASPSPVVPAVDRWAQIRKNAADRAAQRQAEEPPRRDYSTNKPIDGNSDTSGEETIESRVARIKARVAELTGNMEGVSPPGAARAPPPIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL15</accession>
    <name>A0ABR3YL15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED4</name>
        <name evidence="10" type="ORF">Sste5346_009479</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019258">
        <property type="entry name" value="Mediator_Med4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10018">
        <property type="entry name" value="Med4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="313"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="159"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="314"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="386" mass="40467" checksum="9AFD25A627660F6B" modified="2025-10-08" version="1">MDKFIDARFDRVEKALTTLIDSIAKYNPSPALAEDLLAADRELNSGLEELQTHQNNHLRIQSLKEDVAALDGQIKSTLLALAASRRDILAAPATEFPEDSVNRQIRDETKHYPFTYEELMSYARRISRNTVPGPGQTDGSEFFAQFGGPVPGAAGGDGSAPETAAPTPAAAATPGAGPSSVVNGAVGTPGGTAPASATGTPGGAGGTGPGTGTGTAAPTPAPFATSGGAPPPAANVPNVLPDDLKNYIAPTAGTVFSPWPAPDLMMHGGLRALHAVTESACRDKQIALPHLQEPPAQTTQTSRQQPPLRIRFVSLEEHEEQERLRAQREAEEREEREERQRRMDEAAAAASAHHRSNMAGAYGGHAPSAAPAPAQFASTLDMEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLA1</accession>
    <name>A0ABR3YLA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="85" mass="9270" checksum="31795CF0353526B4" modified="2025-10-08" version="1">MHAPKPFLRGPAVRRLPVYAAAAGIGYAIVTYQVANRADPTLANNDSHAAEDRMALLDAYGGRDSLEELEMAARVYEAQRGQGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLR5</accession>
    <name>A0ABR3YLR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HUL5</name>
        <name evidence="9" type="ORF">Sste5346_009372</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000086">
        <property type="protein sequence ID" value="KAL1888746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="771"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="609"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1140" mass="130182" checksum="6C6CFD57F867AE1F" modified="2025-10-08" version="1">MFPTFSGNSRRLRNVNLSGQRHSNPFTAHSLSPGTGSGASKTVADAQAGRRQRQQEREELKAARLIQRSWRGHRSRRQVKTGRREALKELYFSPSPALSPEDRIPRAFPLLVSSFDDRDEASIELLYLFAKDLASTKYVAITSGQLPQARLWHLVRILTLALNQDRLKSYYKMVAKFYTKDTDVLGENTAEYLQKAVLVPLSTADSILKAFTEQTYHEFAASFLTQPILLAETTVASLSQHINLDTLSQAVIDIYGAGTKKPIHSADELLWLLAHVVDIQRRLSGESQGSSLYLRAIYTQLSFLSGDIRVRLASTQKTEDKTPEEDYLATQIRSLVDKEEITKLLEQFAASQSSSSGQDYASLLAGYAIVLIRCFPDKGDDIRMQFFLADLPTKAGPVPAVRFFWEASSATSLFGQVLKSPKATLDYLLQRKRFSTTSTTSHSESTWDREWRTVLLFLELYTFVLRLTDDDDFFSGFSSSQSPFRETKKQPSSRLRSSALSLDALKSLTSFLKNLSFTLLYNASDLLQSDSSDIAFQPSYSTKSKRASEVGNYFVVPGLDFRMFKTIVTTAIQMLYERDSRRKFLPNDHWHMTSNFDMAQFVPAVVTEEQRQHDLRHAVDADDDRDMDMDEEDSEDEEMQEPSHSATSRAFARTSRYAMLEKMRRQRDKSNRERLMATIGPKLEILRNMPYILPFEARVRIFREFVQLDKLRRREGFADPDAWRAHIMDRHGGWGENSPARTIVARHSARIRRDAIFDSAIDQFWELGEGLKEPIQITFIDDFGNEEAGIDGGGVTKEFLTCALMQVLSPQDELFASNKENAIYPNPMKLDQLKVNLQKYNYVEGTEEWNEQVAGMLRHYEFIGRMIGKCLYEGILIDFVFAGFFLLKWALSATDSVYRANINDLREMDEQLYQGMLQLKNYDGDVADLDLDFTIEDQVSSNNNERMQTETRNLVPNGGKLRVTNENRPLYISYVARHRLMAQPYLVTKAFLRGLGTIIDPVWLRMFNQNELQRLVGGDSSEIDIDDLRRNTIYGGLYQIGDDLQEHPTVKLFWDVVQSLPDDDRRLLLKYVTSTPRAPLLGFSQLSPKFSIRDAGTDEARLPSTSTCVNLLKLPRYSTEETLRDKLLYAIRSNARFDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM94</accession>
    <name>A0ABR3YM94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_008854</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499566" description="FAD-binding FR-type domain-containing protein" evidence="13">
        <location>
            <begin position="23"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="487"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="728"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="746"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="832" mass="92032" checksum="3F1C3FFCC47B2F73" modified="2025-10-08" version="1">MVAFKSLLLYLSLSLTPAYVVAGGGKPHGFSPSAPSYDDYCFLTIYNSISSYTFQLPGTVSSTTSASSSSASSGGGGSRGGSSSGHSGHKRAELQKRRKGGGSSSNACTLNLEVASIYASAKAYCNGKQFTAAIPYWQSLCTSGGYTLMDLTEIEANVTQAYINSLPVLNPDSNSTSAAIEKAVILDKAYYEVAYHTNYAHDYAFEQDALFSWGFLGFWGGIMVLGMVHKIVTVVLAFFADRRLSSRRDVEGAGTIAAPSAPSAADPLAKTWHLIRTWFIIPAGFAPFSEHHQRYIYWHTIPRRLDLFIVSAFWITAIVLSFVRYDSFSGNLSYSTVANQNWQLSADRTGILSYACLPFLWLFGGRNNIFLWATNFSFRSFNIFHRHVAWVATFEAIVHSINYTVLYTVYSSSYASSYASNYFYMGVVATITMSLMVLLSHSWLRQKFYESFLIIHIVLAIVMIYALLRHTNFENETWQGYLYPVVAIWGSDRVVRIVRVLYCNLHVKFSKGFIHNETTVRYFADADLLRIEMSPGVRAPFKPGPGQHYYLYQPMALLGWENHPFTLGAYSTKDMPAAHNGVASMTSISSAAGSYGSSLVFYVRPYDGWTQRLRKQCQKAADGIVHPKLLIEGPYGEKADLHHFDTLLLFVGGTGIASAVPYILDHIQCARNGTTRTTNIQLIWSGRQRAMFDHIANTELRDALQRNDVHGNFYITCRAPTTSTAVLGQEEEKKSSSLPQVMAMPSANSNSSDSDSASANYIQVPAYIFTLGRPDVKQLIATTVEQSKASSSKVAVLVCGPAQMADDSRAAVFSALRNGFYGIEYFEETFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNV4</accession>
    <name>A0ABR3YNV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008902">
        <property type="entry name" value="Rhamnosid_concanavalin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF6">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05592">
        <property type="entry name" value="Bac_rhamnosid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25788">
        <property type="entry name" value="Ig_Rha78A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010631">
        <property type="entry name" value="A-rhamnsds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="5">
        <location>
            <begin position="153"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase concanavalin-like" evidence="4">
        <location>
            <begin position="343"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="6">
        <location>
            <begin position="452"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="7">
        <location>
            <begin position="809"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="915" mass="101312" checksum="A742AD1F074A6488" modified="2025-10-08" version="1">MAFVVAVRFDHHRPPNNIGVQDDAPRLSWRIQDRLGGYKQSGCEIELHEVVSGSEQRLLSTVKLTTSSSTLVPWPFDQPLRSRQRISVRVRTWEAAQEATPTPWSEPSVFETGLLDRNDWVCDRLTAPWSSESTGPQPEQLYRKEFSLVDDSAVDHARLYITAQGVYEAEINGQRVGDHFLAPGWTAYDRRLQYQTYDVTGNLLTGANCLGVRIAEGWFCGRIGFEGGHRNIWGPHAALLAQLEITYADGRVQMVRTDSSWVVAEGPIRLAEIYDGEKYDARLEVDGWSLPAAADGDSHRRGVSGWKSVLVMPPLPALVELTSGFGEPVRPVDVIKPVETILTPAGKTIVDFGQNLVGYVRLRNIRGPRGHKITLSHAEVLEDGELCTRPLRICKAVDEYTLRGSSSSEGERYQPRFTFHGFRYAQIDGWLADDIDLLSSAEAVVCHTDMNSAGSFSCSEPLLNKLHDNVRWGIRGNFLSVPTDCPQRDERLGWTGDLALFVPTAVLIYDCVGMLRNWLVDVEHDQRVLGGVPPMVSPNATLPDPVWCRRIPCAIWHDVTILAPWALYQETGDARILTQQYGSMRMWMDTLPRNKTGATHLWDTNVFQLGDWLDPAAPPDQPWKAATDAKMVANMFLVQSLDLMVRIATLLQKPAKEVAEFAADAAAARAQFHQEYVTPNGRLVSDSQAAYALAIGLDILLDPQQRVCAGARLAELVRKNNFRIGTGFAGTPFVCEALFETGHAQVAFAMLLERGCPSWLYPVTAGATTMWERWDSLLPDGRVNPGEMTSFNHYAFGTVAKFLHERVAGLRRVAPGWTACVVAPAVGAAFTSAAAEHVTPRGTISCAWQTHALGEESGVEAMEVSLSVPRDTTVEVVLPTVTGTKTETVGPGDWLFQTTFTRNYEWPVLPLKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP08</accession>
    <name>A0ABR3YP08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="19"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="356" mass="38464" checksum="B85A3C1E7A550FA3" modified="2025-10-08" version="1">MGSIDKFNLPSSMRALEYSSATNFSVVNKPLPQVRRHDVLIQVKACGVCGTDVHIHHGEFGAVFPLVPGHETVGVVAAFGEEVEGFTIGDRVVADNSEVCASCHYCRRGQELFCEKFVAHGVMVDGGFAEYAVYPAHRVFQFRSDTLSDADATLLEPASCAAHGLDKIAPKMGSTVLIFGAGPTGLVLAQMLRENGGCRTVIAAPAGKKMEVAKSLNAADEFIELPRDKEASVATLAKLKSDNPYGFDIVVEATGSAAILEQSIDYVTKSGKLVVYGVYNDDDMVKFSPNKIFKEEITILGSFSQTYKFPAAIDYLTRGRVAVSGIVNKTYKLEQWQECLDAMANKTVIKAAIVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP25</accession>
    <name>A0ABR3YP25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009092</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09000">
        <property type="entry name" value="GH43_SXA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF12">
        <property type="entry name" value="BETA-XYLOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="5">
        <location>
            <begin position="306"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="516" mass="58511" checksum="A35495533A250941" modified="2025-10-08" version="1">MPKRGHDLDVPTHYIATSTFKWFPGVQIYHSRNLADWALVARPLDRKSQLDMLGHPDGGLVYTDVPRKEGSFKDTHNFIVTAPAITGPWSDPIYLNSSGFDPSLFHDGDGRKWLVNMLWDHRRRPQLFAGIALQEFDVASGTLVGPRKNIFQGTDTQYTEGPHLYKRNGRYYLLTAEGGTQYNHTCTLARSRDLAGLYEVHPQKHILTSKDAPFSVLQRAGHGDLVDSSDGQTTYLVHLTGRPITQRRRCILGRETAIQEAYWGADNWLYVKGGPVPSLYVELPSARDEAAYWATQHYSFGASDGDSYKLDPDFQWLRTPEPERIFRVNESGLVLICRESIGSWREQALVARRQVYFSYRAETIVSFRPMDERHYAGLTAYYSQFKFFYLTVTADTVGQRELLIMSSQASFPYGDLDLQYLQERVQVPNEGKIRLALTIRGDQFQFYYAMEGNTDMTKVGPVFDASILSDECGGPGSFTGAFVGMACSDLNGTALPATFEYFTYEPLRDKSDRYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA9</accession>
    <name>A0ABR3YPA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF6">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046506293" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="140" mass="14662" checksum="32762095E1798449" modified="2025-10-08" version="1">MKLSSILLTAAAVSVDALTFTNANFYNISIGNPFNITWADASGPVSLTLLKGGTEPFFTNMTTFANNLSGTSYVWTPSADLTSDTYLIHFADTGGGSAYGFYFALVDAPYSLSTTTTESAAAKTTAATTTAAPQSTYTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ2</accession>
    <name>A0ABR3YPQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">V-type proton ATPase subunit c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">vma16</name>
        <name evidence="12" type="ORF">Sste5346_008351</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="47"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="131"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="200" mass="20376" checksum="B0F02AEEC9378701" modified="2025-10-08" version="1">MSLSYGLGGTGSALLVVGAYMLFTGSGEAFNVGAFLESVSPYAWASLGIALCIGLSVVGAAWGIFITGSSILGGGVKAPRIRTKNLISIIFCEVVAIYGVIMAIIFSSKIQAVSGADLYSGDSYYTGFALFWSGLTVGMCNLVCGVAVGINGSGAALADAADPSLFVRILVIEIFSSVLGLFGLIIGLLVSSKAREFGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPS4</accession>
    <name>A0ABR3YPS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41677:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41677">
        <property type="entry name" value="YALI0B19030P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="45700" checksum="EAD52511AB99A530" modified="2025-10-08" version="1">MSETMTETITATVATTTTVVAEAPVLPFEPAIHLAFEPPAARHSFTELGLDRPTTAPDVCYTDPFPLFSAEGVRMIRQELLSKKVLDKHLTSWPRAPCIISYHEETATWINNMWNHPAVRECIETAFGEKLKILGRRGEVGHCNVQLGFGGKEAVYDLKAEPSPPKTESEKDDDGPYSKTLTDAWHRDSTQLVVVVMLSDTSTMDGGETAIRVGGGKVLKARGASAGTAVLLQGAHTPHAALRATNIHERISMVTSWHFANPDLDDTGTSLRSVKPDNPLGAVITDDFFSHKLKKLRDRIDVQLERLEERRVRPTEDPHRPLLGREAIEGWAREQVSLLTHTAWELCERYPKWLYQDVPATVMGDYAKHTLVADASTASTQKDAHTATSNPSQPSVAVGLGFLAGLTAGVVLARRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQB5</accession>
    <name>A0ABR3YQB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone H4-like TAF Taf6, SAGA complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">taf6</name>
        <name evidence="7" type="ORF">Sste5346_008504</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="6">
        <location>
            <begin position="14"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="52282" checksum="7B50B4E148F76734" modified="2025-10-08" version="1">MAVKSEDAAAVRLLWNPDNVKDVAESVGISQIGDDALRCLSQDVEYRIGQVIVEALRFMRAANRTTLTVQDVSLALRVLDVEPLYGYESTRPLRYGEASIGPSQPLFYIEDEEVEFEKLINASLPKVPRDASMTAHWLAIEGVQPSIPQNPTTAEVRSTQELVAKGPGANPALAALAGNDNVGFKPAVKHIISNELVLYFDKIQAAILDDNPDEEVLRLRQAALESVRSDPGLHQLVPYFVSFVATQITHRIDDVTILRHMMELTTALVENPHVFLDPYVTPLCAPVLTCLLGQKLGLGGDKAAAGGGASANVQGTDAVRDIYLLRELAASLLGLLARKFSKSSTLLRPKLTRTCLKTLLEPDRPVGVLFGAVAGLSAAGGPEAVRVLLLPNLKAFDTYVLQPLQERGASIAVELEMLVAGGLLKAIRTLVPATPSTPNANGSSGSGNSSDVETAELVDFLGPVVGQRVAQLGDSRLNAVILEARNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQZ7</accession>
    <name>A0ABR3YQZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="381" mass="42633" checksum="0DBDC47D05BBDEF6" modified="2025-10-08" version="1">MPFAQLVLGSPGAGKSTYCDGMHQFMGAIGRQCSVVNLDPANDHSNYPCALDIRSLVTLEEIMADDNLGPNGGVLYAIEELENNMTWLEDGLKELGEDYVLFDCPGQVELYTHHNSLRNIFLKLQKMGYRMVVVHLSDSFCLTQPSLYLANILLALRAMLQMDLPHVNILTKIDKIASYDPLPFNLDYYTDVQDLSYLQGALEEESPALRSEKWSRLNTAVADMVESFGLVRFEVLAVENKRSMMHILRVIDRAGGYVFGGAEGANDTVWQVAMRDESSMLEVRDIQERWIDNKEEYDEIERQESEQEQKLREVQEAAARGMDLDEGNRVEELSPEPAAATPVAGSSATGPAADDDDLFDDDLPKPSTTDNGIKVVRRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRR2</accession>
    <name>A0ABR3YRR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="33"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="518" mass="58037" checksum="BA041CCD919E64ED" modified="2025-10-08" version="1">MARHAAPTGRTLADVLPPNVTFWSPHIVQLNLRLFVMLIGGICMGFDSAMMNGLQDLETWRDYFHDPRSWLLGVVNAVLNVAPIVGGMPVAWLSDRYGRLLCVRLGCLLLVFASALQAGSRNLGMFVAARFLIGFGIELCVVSGPVLVSELAYPAYRSQMTSLFLCFFYVGSIIASWTIFGTSQMANTSWSWRIPSLLQAFVPLVQGCLSFLVVESPRWLYSKGRQDEARDILVRFHGGGDPDSPLVDYEMEQIREYFESDSEAKKLKWTGLWKTVADRKRLLLVIYIAFMTQVCGSALISYYLTLVLNTIGITTTTTQTLINAILSIVCCLVAVIGAFLVDRLGRRFLWLSAVSGMLITFAIWTALSAQFEKHNTDTLARGVLAFVFLFQASYSFGITPLSFTYAAEILPFHARQKGIGLIYMCNSIALIYNNMVNPVAMDAIGWKYYFVFIGLLVQWLIVIYYFFPETKGQGLEELQNLFEPDTIQNLAKTDDLEAISREEVDRKQAMTAVTEHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSJ1</accession>
    <name>A0ABR3YSJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Uridylate kinase</fullName>
            <shortName evidence="9">UK</shortName>
            <ecNumber evidence="9">2.7.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:UMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Deoxycytidylate kinase</fullName>
            <shortName evidence="9">CK</shortName>
            <shortName evidence="9">dCMP kinase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Uridine monophosphate kinase</fullName>
            <shortName evidence="9">UMP kinase</shortName>
            <shortName evidence="9">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">URA6</name>
        <name evidence="12" type="ORF">Sste5346_007974</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UMP + ATP = UDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Predominantly cytoplasmic.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.14" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03172">
        <property type="entry name" value="Adenylate_kinase_UMP_CMP_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006266">
        <property type="entry name" value="UMP_CMP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01359">
        <property type="entry name" value="UMP_CMP_kin_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="9">
        <location>
            <begin position="172"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="9">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="152"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="234"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="36469" checksum="ECB08B5800AF8DCC" modified="2025-10-08" version="1">MASLFPRALLRRPLTALPRAATASRASTCRVPTTTAASAFNLPHSALRPLTARRFYSDNNSSNNSNKNSGIPPPPPPPPPKPSNIKFWPFVVVIALGSGGYMLLVNQRNNNKMSGDKKSTGKTSGGGSGSSLPKPTFSTDDVSVVFVLGGPGAGKGTQCARLVKAYGFTHLSAGDLLRAEQDRPGSQFGQLIRDCIRDGAIVPLEVTVKLLENAMQETIDNKKTEKEHKFLIDGFPRKMDQAIAFEQAVCPAKLVLFYDCPEDELERRLMERGKTSGRADDNAASIRKRFRTFVETSMPVVDAYEKEGRVVKIDATSTPDKVFAATQKELGSRLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSS2</accession>
    <name>A0ABR3YSS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="625" mass="68358" checksum="6760DF5572385904" modified="2025-10-08" version="1">MEGNDTKSGVADNSTAARARRRVCNLTPSQVEKKRAIDRTNQQHWRQKKRLYIAELEAEVARLKESLDASRAKLRVYEGDNDDDMSAEQGEDPSSSTQDLNGESSVRGISAVPAVPSLPTLLPATSRPNNNAIGSASPGGTDGSAYLSSTVPQVHGRQAAAGTGTSSASSDVSWPLSLIAPNITSRARQAGLLSLQSATQLQLQAQAQAQVQAQAHARLDNGLQLDLFETTPFQLYDNTEIDGHVPVDVDEVFGAQPNYTDFLSALDPDYQRQEQVRHQSQNQQQQQQQQQHNPYYRQNIQRYQALYGATPPSPFLTNLSYMPYYLAGRYSAPRPGMPDWMVLPLNMPVATELDKLFLITSQALVQRYSTNEFSQPMFPTIEGLMSRLSTDNKPRSARNSSGPSSSVMGEELLQALAAASAGGASSILSASALTAAARASAVAASAANPPSPADSSSSGDDESSSVIASRPVLAAVATHVVWKSPLKHLTGRLSFLYKLAIYLRWCLCPTKENYEAIPEFLRPTPLQRRVPHPAWVDMIIWPDVRDSLIRGGDYSAFELLRFVLGNTVSINWPYTEAHTFMECADGKRLALNPIFEAHIRNLDNYSVGYQAAMAFPVLSRYVRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY4</accession>
    <name>A0ABR3YTY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="30"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="369"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="56779" checksum="72CFC4DF8BE46FBA" modified="2025-10-08" version="1">MDWLDPTDDLRVVLAVIRLPATDRENYGGPVFFNPGGPGGSGIWSMRDHGRNLQDVVGKRYDIITFDPRGIGASVPRIECWASVQNSQFWDLQDVGVVDAHPGTIYDAYARMSAYTTVCEASLGDSGILRHSSTASHARDMLEILHQLGEEKLKYWGFSYGTVLGGVFAAMYPDKVERLVSDGNVDLREWHNKEHLNFLHDTDKVMQAFFDLCHRAGPDACDFYAPSPEAIKKRLETLFANLKVRPVVVSMDKDLGPEIPDIVTYSRVRKVLSSTLYQPQRAFPRFAKTLLALENGNGRPFYEQTSGKVQFAAVCQAETIPPTTPLTGFDEGTSDAFGAVMCSDSVPITETVEDFMELIKSYEDMSYAAGATNANFPIACVNRQVRPKWRFSGPFEGNTSFPILYVANIADNVTPLISARNNSAGFPESVVLVQQAYGHTSLASPSTCTAKIIRDYFQKGLLPAVGTECQPDVLPFGLPTGFVAAEDAELSLAISELSEKASAYRDRMLTLKLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY7</accession>
    <name>A0ABR3YTY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-dependent oxidoreductase 2 FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF10">
        <property type="entry name" value="3-OXOSTEROID 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="51862" checksum="CCB644E6A8EB7591" modified="2025-10-08" version="1">MESLNVDVLVCGGGMSGLACASFAARAGAKVLVVEKQAVVGGSSNYSAGMFWAPQNYEKLRGWVPDGDPQLQKAFLDEYLQAVQWMRDHDVPTAPRFDGIMTIGIGFPITIRALQAVQRSWIDSAAQKSEIWTGSQVVKLNQEAPGVLGSRVAGAVVKNNKTGKLYNINARTVVLATGGFQGSPSLTSRYLGQGADNIFVRANKGSVGDGLQLAAGVGAGTSRGMSTYYGHLMAAPLRVEDVDPKDYLPLAQYQSKHCLLLNEAGRRFTDETTGDEIVNQYLAKQEKRRGFLLFNDNTRLQHCVRALFPNAGDIDRLQKAKSHGCRVESAANLDGLVKILGTWGVDAAQARRTIADYDRSVRLGDSTVALDAPVGRGGTPPVALVDGVDGPFFAMEVQPSITFTYGGIAIDTEGHALTPDKTRIPGLHVAGVDAGGFSNTGYTGGLSLAFVTGLWAARRVTKELGLPEPRLPSANPADVKATISAANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU15</accession>
    <name>A0ABR3YU15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 2</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12 16" type="primary">PSD2</name>
        <name evidence="16" type="ORF">Sste5346_007591</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endosome membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C2 domains have an essential, but non-catalytic function. They may facilitate interactions with other proteins and are required for lipid transport function.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04039">
        <property type="entry name" value="C2_PSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04024">
        <property type="entry name" value="C2A_Synaptotagmin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00663">
        <property type="entry name" value="PS_decarb_PSD_B_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033179">
        <property type="entry name" value="PSD_type2_pro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF17">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5044925888" description="Phosphatidylserine decarboxylase 2 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044925889" description="Phosphatidylserine decarboxylase 2 alpha chain" evidence="12">
        <location>
            <begin position="1099"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="31"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="289"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="588"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="200"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="436"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="483"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="526"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="700"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1135"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="708"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1146"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1175"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="954"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="1012"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="1099"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="1099"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="1098"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="1099"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1184" mass="130526" checksum="D7E8EE920CA48210" modified="2025-10-08" version="1">MVRIIPNRLKPSSGNSAASSAVNSRSASPMRGGKGDPASLNNRDTGLHIHVVIIKARNLAAKDRSGTSDPYLVLSLGDAKHATHSVSKTLNPEWNEICQLPINGVSSLILDVCCWDKDRFGKDYLGEFDLALEEIFVNDKTEQEPRWYPLKSKRPGRKTGVVSGEVLLQFTLFDSTDRSATSQQVMEKFSAFVRATAPDTEDVAPRQHHRVPGLGVGIPKLGARRGSSNPAPTSAPALTRKISNTTNTDDYEDEDAYDDEPVLEDEDPSKPETVEKRKRRLRIKGLKKKRRENPYEFINGGGDVLGIVFLEIKNITDLPPESNLIKTTFDMDPFVVASLGRKTFRTKTISHNLNPVFNEKMIYQVLSHEQSYSFSFTVIDRDKYSGNDFIASTSLPLKEFIERAPKADPETGLYDLREPPEYVPLAQRGRFKRLGLSRSSSSQSLSKQSRPVPAKTPSASAMSSSGTTALEYQIPEISGLPDPSVALGDVTNMPQVTTPSDAGVSDPMAAPGLTRQISAGASGLLTAEGQTSGSSPTSSTGEPGSGDGDDQDFTTFTLPLKMKNLDKWEDKHNPQLFIRAKYMPYPALRQQFWRAMLKQYDTDESGKISKVELSTMLDTLGSTLRESTIDGFFDRFKKGPIYGNGGEDDFSDLTIDEAVICLEDQLDAKPKPTSTSVTDKLKDALPDGVVDKAKAAVSLAVPGQSPNTPEATADTPAPPASSSSTAGSPEIPPLNSALNNSDDGEMLGHDDNERGGEEHVVEIRECPICHQPRLNKRKDADIITHIATCASQDWRQVNNLVMGGFVTSSQAQRKWYSKVITKISYGGYKIGANSANILVQDRMTGQINEEKMSVYVRLGIRLLYKGLRSNNMENKRIRKLLKGLSIKQGRKYDDPISRQEIQKFINFHQLDMSEVLLPLEEFKTFNEFFYRALKPDARPCSAPNNPRIIVSPADCRSVVFNRVDAATQVWIKGREFSVKRLLGDVPAEDAARFENSALGIFRLAPQDYHRFHIPVDGVLGKPRLIAGEYYTVNPMAIRSALDVYGENVRVVVPIDSEQFGRVMVVCVGAMMVGSTVITRKEGEHVKRAEELGYFKFGGSTLVLLFEEGRMKFDDDLVENSSGALETLIRVGMSVGHAPNEPQWRPDMPKAETDVTEQDKIDAKRRIQGSTMAEDITPEDSGGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUE7</accession>
    <name>A0ABR3YUE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047129252" description="F5/8 type C domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="597"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="764" mass="81731" checksum="F532348FB6B8FD58" modified="2025-10-08" version="1">MVTYKWLAFVAAGRLAAAWGTDTEDITYILPIYEGALANDSRTNDLAILNGMKSMLGVGGANTKLGFSFSSWCLSRDVSSAANNFTFDPTNLNYVLGLAVDLDLPILVHANNGRWADCCTSNSDGGWNDALLDQIAAQPDTTMQNSAGDSLYGHDYGSNYFSFSRYNDYYRSYKRRNLQASMSTIAAWAADHPTLFAGISLDSETLYANDAADYNPLIVQEWKEWMQNTGLYGAGAAYFGQGRVPAFTSIDDFNTATGQSFASWDDVTPPAPLSQGNPFTEEWQRWRVQAIVHTTSDETSWIVEAGIPRNLIYGHQTPELEYYNFGDDLTTATAAFGAGGYTAYGRAPLDFQSIDTPLRADGTNNFGLFELNPLSTDNTFSYDTLTTLWSDGAKILCPNAFENVTAKDQYSLFDSPTTGDTWGNNINAFLSAYANTARLQQPPGWNPGNKVFDLYDSFSDATESGPDNHIAANGSSGGVAVKTVYEAVGGVITYSIDLPSVSDGQRLNFYAAVGIKDGAGSGGGTATFQAAINGDSLLLGNGIIIPPTYWTWKHWLPVMADITAWAGQTVTFTLSTTGNDYYGWTQWGSPAIYQTPNGASGGDTSSSNLALDKVVSASSNDKSAPGGGWGTAYLTDGNVRGDSASNGWSSVSHDSSSATEWVQVDLGSSQTVGKVVLHPRSDITTAAGTGFPVAFDISGSTDGTTWTTLSSQPSYGASIKAGRGEVITFESANVRYVRLTATELSGVGGESGYRVQFAELEVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUR6</accession>
    <name>A0ABR3YUR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arf/Sar family, other</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007538</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="18219" checksum="EAA745476257775D" modified="2025-10-08" version="1">MLGLQNAGKTCLLNVLSGGDFTYDTIPTIGFNMKRVQKNNVSIKCWDIGGQPRFRPMWERYCRGVNAILFVVDIADIEKLQAAREELHSIMEQESLEGIPLLVLGNKSDLQVKVSVDELIDALDLKGIDHREVSCYGISAKEETNLEAVLSWLVKRANELQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUY1</accession>
    <name>A0ABR3YUY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polycomb protein EED</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="367"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="461"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="63815" checksum="8DA23E7D04FEA9B3" modified="2025-10-08" version="1">MAPALPSEWEMPKLRYSLNFEDTKSSADDANSDTEFFDVKFYPYNPPGSNPIIRVIRDEDEGALNCSCTWARDPQTERALLCVAGRDAKVKVYNIRDGEAVTSFVGHGGEINDLATCPTNPHLIVSASDDTTVRLWSLDPVHKKQPCVCLLGGEGHSWNLLSVAFHDSGRYVISAGHDQVINLWTLPDIPNEHVEVPIIVHFPHFSTSEIHTGLIDCVAFYGDLILSRACLEDVIVLWRIEGFDSTAEPPSPEQAPSNQDTTKVTRSAFHVPLITSPSAVASANANNASTVAASTTPQYTRLLQLHTPGCGPQFFMRFGLFNVAGHHPMLAFCNAAAKIFFWDFTCFSAYRQFITANHRRERQMAQLGNGANGTNGTENGAGAGASSVVDEGPVPRPPWMRIVVPRKRPTANGGHSNSNTNSSSANPGGRRTRDAANGLGLLGSVHRDGEGSDHESSVVSGAPGAAAEGASIAAGAANGGTPSASTPVPTTTTNTTGATPKGRSAVGYSMSDLYNKETLDDWDSKYNANDPHVLVKAHKAETTKGLSAVGRQAAWSPEGEWCVVVGSNSRVMILQRWANSNNSDNNSHPVEEAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV08</accession>
    <name>A0ABR3YV08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nicotinate-nucleotide pyrophosphorylase [carboxylating]</fullName>
            <ecNumber evidence="6">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA6</name>
        <name evidence="9" type="ORF">Sste5346_007466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Hexamer formed by 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="entry name" value="Quinolinate phosphoribosyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179:SF3">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase N-terminal" evidence="8">
        <location>
            <begin position="44"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase C-terminal" evidence="7">
        <location>
            <begin position="126"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="304" mass="32236" checksum="947FF0CC6B3A90AB" modified="2025-10-08" version="1">MSSTRVPLDHGALSALLPPSWTEQVAQWLAEDTPSFDYGGFVVGDVPRTATLWAKSPGIVAGVPFVNEIFKRCGCAIEWKVEEGAHVGSPDDNGGKTNCATVSGPARGLLLAERVALNILARCAGIATRTHEVLTALRKAGYTGRLAGTRKTTPGFRLVEKYGMLVGGADMHRVDLSAMVMLKDNHVWSRGSITDAVTAAKSVAGFALKIEVEVQSEEEADEALAAGADVVMLDNFTGDGVKVAAASLRQRWAAKGNSAFLIEVSGGLTSDNIDAYVCNDVDIISTSYIHQGVPHVDFSLKINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM7</accession>
    <name>A0ABR3YVM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transglutaminase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052557">
        <property type="entry name" value="CAP/Cytokinesis_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333:SF5">
        <property type="entry name" value="TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="2">
        <location>
            <begin position="486"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="808" mass="89259" checksum="91C9447C43FB8EED" modified="2025-10-08" version="1">MTEVEEPQFSTLAERIAALNKQKNFSSGPPAASTPPPIVRSSSVASTASTATTTTTTNGARRPPPPPPSAKPAIPAKPAKPPGIGAAKPAVSTPSYTPPPPAVAAGFRGPPPKLPPRTASATSTATAGSLQRAATTAALVDRRPSSESVRSHLSTNTTLSRVSSMTTNSVNSNVGGRKLPPAFGTTKLPDLPPSKREREAREREEAERQREEQERQREERERQREERQREEREREDRERERNDRQRDQGRGGWNGQRNNSNNGRDWDDRDRQYDNGRDDERAPALPSRPGGGGGGGRGGPRRSQYDDEEPSGPALPPRLPPRRRTDDFDNNDDEGPAPALPSRRNTVKSALDLGFNSGKSLPRRPGPQQVPYNNRRRDDIPEDDDEAPPPIAPRPSRALVAAAVRGGGNNNNDYEDRPSLPSRPRPRANGGGGVPGFYPKKSEDEECMKCRDFSGPDHVAAQFPIARLPRRDPIGYLAHNLCDDFPSETDKARAIFAWCHHNIAYDVDGFFGGCIPRGQSMEERIFSGKAVCEGYAKVYEALALAAGLECVVVTGHGKGFGFNTVRPGDPIPPADPTGHAWNAVRIDGGDWKLLDACWGAGNVCDKRAERYEKKFSPEMFTMDNETFGERHFPENPRHFFREDGRVPTWGEYVVEKMSADPVILYSNGPKQFIAKESMEPASQEIEVSRGDPNERIEFRLGRSCRHWTMDVGGEGLRPYPMMLKSVSPDGQKRGNGDSEMFDVEFDEPLWFWADVPRRRLGRPGDMLFCYAITTMDGRDLRGATMADYRARMGRCSMSMQAICSWKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX95</accession>
    <name>A0ABR3YX95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SNX4</name>
        <name evidence="13" type="ORF">Sste5346_006953</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06863">
        <property type="entry name" value="PX_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="116"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="444"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="462"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1892667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="616" mass="66443" checksum="73CA17686B05B339" modified="2025-10-08" version="1">MAVIDQDNFSNISWNSDQRTNDEEGASANDNTITSTNQNKNGGSSGINNNNSTKNIRSRMADDDFDQPLSPGGDSRGKQKQKQKAKQTASSGPGGPSSAPDIDYDGHDANVLGPEILQCRVFSPLTENEGGSNPFTSYLVSTTSTFPTFQKPTVSVRRRFTDFLYLYNSLSKDYPACAVPPIPDKQRMVRVTGDRFGPEFTNRRAYSLQRFLFRLSQHPVLRRAPLLHSFLESGEWNATMRSHSGRVGGSDGSSYGAGGGYGGAGGGGSSGAGGSGSEQGVTSSMFDAFADSFINVFTKVHRLDRRFVEVREKSDHLDKDLNHVESVFTRVVRRETDLEADLKDLAEQFQKLITLEPGVEDAVRAFAASVEDQLAGLRGLRDITDQDYIGSLRDMVAYSGSLKNLLKAREQKQLDYEQLTEYLNKSTADRDHLAMASGGYYHSGLSSTGGGSISRRDSSSGGVSGGLGEGSSAGGAGGNGADSTRGGGGSTSTGGGVASYVTGGGGGALAGASGFLRSKLEDVRGVDHEQSRRERQRKLELRVDELTTEVERAKKTSEMFDEEVVKEVADFERIKRIEFKKQLGGLADAHIAYYDAVSDVWEAYVREMEKDGVLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZV4</accession>
    <name>A0ABR3YZV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM192A/Fyv6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006413</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="51"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="228"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="271" mass="28482" checksum="C0BEC0DA4817A474" modified="2025-10-08" version="1">MSSRFVSGGAIDAATGDAVDLAKVKESMKSTSTATTSTATTSTTQSSTPLVSSARQAEWAAVEKELEADRQRRAEARKALGSGAQEKSLYDVLQANKAAKQAAFEEAHGLKNQFRALDEDEIEFLEGVEEDARREAARVAAETAAGLDAFRAAQTKGGGDAGGDKSDDVDNDDTVEKLVDDSAWAVGRKRKRRGDKTDKAGAFPNLKRKGSSAAEKDKEEPEAKKETTTSASSTAKEPAKASPKPIPATAPKAKPALGLVAYGSDDDNDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZW4</accession>
    <name>A0ABR3YZW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="4">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SPO11</name>
        <name evidence="13" type="ORF">Sste5346_006431</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TOP6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="11">
        <location>
            <begin position="63"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="12">
        <location>
            <begin position="132"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="37173" checksum="356F95A8AE1874DF" modified="2025-10-08" version="1">MGSTVNKIEQIIENVLDNVNRGQKLSIPFSRRAKPRAGRVIQKSQSRGFVSFPGKTEAESKLFTQVLSILQLSHQALLSGTFVTKRNIFYQYRELFRDQRVVDGLVDDIAYTLSLGRDSLNIELDLSACQWILVIEKEATFRTLAASGYWNTSMAGPGALVTSKGYPTLVTRWFLHHIHESAPRLPIYGLVDYDPHGVRIFRTYKYGSQSLSHETNTTVPGMKWLGIQSCDLMYPANSVSPRHWSALDDVLPLTDADRRTAACLLKDMVYNANVGTEESSYEQIREVQVMLMLNVKAEIQAADDYGDLAEWLDEKLYRAQEGDMEEMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0J1</accession>
    <name>A0ABR3Z0J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alternative oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="53752" checksum="1E22B80A9D98AC0D" modified="2025-10-08" version="1">MVAKDVRERLAIIIPLTLAFFFAWSFRLFGFRDAVLAVLSGDAPTTTTSPPTSSLNPFGEAAFIQQAMAVEFPAPIDYGPIQEVCSRTPFREGLVFTCEGQHGGIGMLRNQMLKCIRYAIHGGGAIVIPSMAVRNKNDLKDIETATEMPLDYLLERATFKKHLAAGCPQMRVFDRVEDVPFYSQRHGVPLQLLGDQFEPNHPRTGLEHPRDWRRNFDAWLQKQSVHPEKQKPVHIQMEQSFLEYPVRDDGDAFVHEFGKILSFRNDTRELAAKVLYALRTRFELPIDPTVAISPNSYYGAHLRLESDAIWAWPPEQWRFSRMKDQFEEQFRHLEETGLSTVFVASGNQTVVHLFATYLRQRIASDLTARVRHVDVVTKYDLLSESDLQRLSAMTFDQQALVDFLVMFKASAFMGVAFSSFPWNVALRRHELSKYSAYANEGSDLLRDEYSVIMGMAADYPYVDSFVTSIWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0K6</accession>
    <name>A0ABR3Z0K6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF8">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044987009" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="56265" checksum="0EF630C33B6753D8" modified="2025-10-08" version="1">MIPKTMCGAVTGLALLGTELAHGHVISQPGCGGLHIPISHSDFRIVSTKFTPVFNYTSVTGFDFCNVSAILTHPGSNDAVYTELWLPLTGWNGRFVATGGGGLVAGFESSLPPFVKEGYASAYTDAGLTLNNTIDPSTGAWAITSPGHLNNALIENFAYRSIHDMTVFSKAAIKAFYGSTLKYSYYSGCSTGGRMGYFAAKHYPDDFDGILANSPAINTPQVSPADFWPSVVMANSVAPPQCIFDTYLDAIISFCDATDGVVDGLVSEPSLCHFNTSSLIGQTVNCSSPDAEIQITAEHADVIAKTLQGATSTTGEFLWYGLAPGAPFTGLADTVYVNGSVIPVPFSSAQFWIGYFVDQDPNAQTATLTYEEFDTAFYRSVSLFTDILGTDNPDLTSFRNKGGKLITFHGLADPLITHWGTTRYRDRLQNKMGGAAEVNTFYRLFLAPGVGHCGGGTGPNPADPWAALTDWVEHGVVPHTLHANTSTVSRNLCPYPEKLQYKGRGDVNLASSFHCVASDGSKYKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z191</accession>
    <name>A0ABR3Z191_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Yos1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006291</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the YOS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013880">
        <property type="entry name" value="Yos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858:SF0">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08571">
        <property type="entry name" value="Yos1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9591" checksum="069609975E58A1DD" modified="2025-10-08" version="1">MYLLGGFLYVSVLLINAIAILSEDRFLARIGLSPSTYDPTFGQPGVGGVSAGDASIKAKIINLIASVRTLMRIPLIVINTLLIVYELVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1M0</accession>
    <name>A0ABR3Z1M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="92"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="330" mass="35714" checksum="A33F91AF387E097E" modified="2025-10-08" version="1">MTSHTLIPFDKELVGVLQALGTRAPLCRQSLGFLRRIVNGKSTAEAVLIDPEIAHEARTIDSPDGRQLDVAILRRKDFTAGPLSTPPSAAVYFIHGGGMVAGTRFSDISALFGWIKACNIVMVSVEYRLAPEHPYPAALEDCYAGLQWLFASTSELHIDPRRIILAGASAGGGLAAGVALLSRDRGGPRVMAQCLMYPMLDHTTSSASSKQYMTEGLWTGASNIAAWDMYLAGVKEGDHERETLVYAVPGRAADVSGLAQTFIDVGSAEPFRDEDINFAQKLSEQGVPVELHVWPGAWHGFDQLVPTAQVSQDCAQARLAWLKRVLRNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Z4</accession>
    <name>A0ABR3Z2Z4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonucleotide-diphosphate reductase (RNR), small subunit</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RNR2</name>
        <name evidence="4" type="ORF">Sste5346_005605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="403" mass="45830" checksum="515E2C2832A68F62" modified="2025-10-08" version="1">MATNVTPSKAAASAIESFKIESPVKKLDFGDANKENILADEAKPKELVKEEAKTEEAKKAVAPTIKAAEADEPLLQENPQRFVLFPIKYHEIWQMYKKAEASFWTAEEIDLSKDLHDWNNRLNDDERYFVSHILAFFAASDGIVNENLVERFSGEVQVPEARCFYGFQIMMENIHSETYSLLIDTYIKDPARRTYLFNAIETIPCIRKKADWALRWITDEKSTFAQRLVAFAAVEGIFFSGAFSSIFWLKKRGLMPGLTFSNELISRDEGLHTDFACLLFSHLNNRPSKQVIEDIIVDAVKIEQEFLTEALPCALLGMNSTLMKQYIEFVADRLLVALGNEKVYRSTNPFDFMENISLGGKTNFFEKRVGEYQKAGVMANSAKKEGEETQGKGEGDFTFDDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z436</accession>
    <name>A0ABR3Z436_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E2 ubiquitin-conjugating protein mms2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MMS2</name>
        <name evidence="2" type="ORF">Sste5346_005201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="7"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="149" mass="16991" checksum="8B47853B0851D9BE" modified="2025-10-08" version="1">MATAQVPRNFKLLDELEKGEKGLHGGVCSYGLEDPEDILMTNWRGTIWGPPHGNHANRIYELKMQCGEHYPQKPPVLHFVTKINLPGVDGVNGLVDKNSFDILRDWETSPKELLSLEAAMMAIRKCMEKNNKLAQPEENTRYEIYKDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P0</accession>
    <name>A0ABR3Z4P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="597"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="644"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="681"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="825" mass="87926" checksum="78825ACAA0DD9C57" modified="2025-10-08" version="1">MDNAADVLAEAHALYARANELYARAGNLTSSNSTSNGTDTSSTTNNDRPASFKVIGIALAISSGAFIGTSFVLKKVGLLRANEKYNEVAGEGYGYLKNVFWWSGMILMIVGEICNFVAYAFTDAILVTPLGALSVVITTVLSAIFLKERLSMVGKVACFLCIVGSVVIVMNAPQESSVATIQEMQHFVVTPGFLSYTGVILIGSAATAFWAGPRWGKKNMLVYLSICSWVGGLSVVATQGLGSAIVAQVGGTPQFNQWFLYVLLVFVICTLLTEIIYLNKALNLFNAAMVTPTYYVYFTSTTIITSAVLFQGFKGTVTSIVTVVLGFLTICSGVVLLQLSKSAKDVPDSAVFAGDLDQIQTIAEQEQPESEPKADAIRGAAAIVRRFSTARQNMEVAELKRMHEEKMREQNELEAIGEDGQPLPPGEQRPPMYEWDGIRRRRTTIGSQRSRSQTVSSRPFTPGAAPGTAGSSTPHPPLGWSHMPTEEELAALEQRSNTPGVLSSIAGTIRGRGLGGRGRSMLLPTYNADADEEQQHQQMRQQELDPKIQSPMHPVQLTEISLPAGRSASGDSGGSAYNRGYGLPSGKTEYVGAAGYASSDAASSIAPPDPPPHSAKRQFSFQNVFRRHQQHGASGAGSTVDSLPEVDDDEYDEYGSSSTDRGYRRQPVASRGYSAPQVKGSTEEERLGLVKGDSRSAPTILPTYDEEDLEGEGGDVYGDAPDYDDYGDGKHPVYTGTATTASSARYGRGITGSPPSPPRAVAVVGSSGEKSRGHKGSGSGSSGDEYGRGRARQPRHVPGKDDSPPPPPPGGHRYSPPRGGDGAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Q2</accession>
    <name>A0ABR3Z5Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017771">
        <property type="entry name" value="Cyanamide_hydratase_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03401">
        <property type="entry name" value="cyanamide_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569:SF1">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="66"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="246" mass="27083" checksum="81A75F19408B65EB" modified="2025-10-08" version="1">MATSNTSEVAQHGWTAIARDPQVVLSSKSSLHEPKSLLVKDIAFPSDDVLVSQVQTYAKEKLAPQTYNHSMRVYYFASAILEQQFPAENATLSRATLALTALLHDIGTTHDHLRATRLSFEFYGGYLALDLVGKQLHPPAPQAQAEAVAEAIIRHQDLGTTGTITFLGQLIQLATIYDNMGGNPGLVHQDTKVDVNKQFPRNGWSSCFAKTIREENGLKPWAHTTALGEEDFPEGVLHNKLMAEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z675</accession>
    <name>A0ABR3Z675_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF97">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="515" mass="55723" checksum="ED66654E2DFC2436" modified="2025-10-08" version="1">MDDIKTAPVASEPAEMGDTEKVQSLAVYDDVGRALYEQAQTYDVAQLEQDAHKVKRKLDFIVLPMMMITYALGFLDKSTLNYANVYGLQKDLHMTGGQYDWVASAASLGWLISAYPASLILQKFSISRLMGGLLIVWGGLCMLTAATTNYGGIFTLRLLLGGSEAPITPGTLMLTSMMWTSQEAPLRTSMWLAVDGVATIVGALLAWGLGHTASDVIPSWKFVFLVVGAITVAWAGVILVFLPDGPHKGRIFSEYERAVLVWRVAKDKRGVKSPKLRMYQIWETLIDPKTWLLCLSSAALGILNGGVVNFKSALISGFGFAGQEANLLGMPSGAIQIAGCVLFGMLAGLKNMKGVAIILSCIPGMVGLIGILTISHDPKYKYSLVACTWLQSCIASPIALSWSLPVVNVAGHTKRSCTLGLIFIFFSAGMIGGPHLFIAKEALRYPTAIIGLLSSYGAAMVLQAMYTALCYFQNKARDEKYGRPADGGDRATDDGALRGFEDQTDMENKDFRFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6P6</accession>
    <name>A0ABR3Z6P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRE3</name>
        <name evidence="9" type="ORF">Sste5346_005036</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 8 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="229" mass="24710" checksum="FD288B151166FC37" modified="2025-10-08" version="1">MEYGKSGQLSEDGIHVDMDRLKKGEVNLGTSIMAITFKDGVILGADSRTTTGAYIANRVTDKLTRVADTIWCCRSGSAADTQAVADIVQYQLNLFAMLNKQPPTTQTAASIFQEVCYANKDALSAGLIIAGWDERYGGQVYSIPLGGSLHKQAYAIGGSGSTYIYGYCDANWREGMEEAEAVSFVKGALQEAIKWDGSSGGVIRMVVLTAAGADRHLYLPDTDYTVRHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z707</accession>
    <name>A0ABR3Z707_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2 type master regulator of conidiophore development brlA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004743</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="871"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="897"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="354"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="786"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="796"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="852"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="979" mass="103177" checksum="95C29F940829EBA8" modified="2025-10-08" version="1">MSPPSTAAGHIVARHLSHGGIAGAVVGSVLGALLIFILVLPFILRAIREHKYHKKIAAENAEMGITGQGYYGGPPGQQFHPLFHQPSQPAGAGPGAVDPSAQGPSDPATTLGSNNSSEGGKPAVSGSSPTPPPGDSSPQSTAAAVAAPGVAAPSRAALPPGGYPINTNTAPYAGPHSASPGGPQHPTLNSAATFPTFGSQDPMMAPRQRSSTMMTARSSNKLSEKLDTIKAVFRQGSTRSSPSRSPTSRSARGGPDSTRSPVEMSFNQYDASNHHTWLMRNQGIDDHSTGVEPGFFEVNTQYLTGASAEYYSGAPLSPPTDPNSHLMSPVSYAPEPPSMIATGLASIASAAALTGVGSGSKKQKPAVSRTDSLKTAATGEDFSPLPLSPTSPLPSVPEGDRGIKPDSEQYDQTSDRGISSPPDGSRSMTTELTPEPTEFMPRSPSYRPLVPSPRLPAPGTVNPRDVWAPATDDERFVHKTAELDRIEQSPQPAVESSPGDSLDVPHVPSISVAASPSDSNFEAEQEEASGPIEASTQPVEPLSPNTEASPDVTDAPSPQQPPAAPSVSAPEQTIIATPAQPTAVPASDLNIDDSSAELQNAQDFQDTQVTEVTKDTANLQAAPTNQIPLDNIGTTGQIDPADFDELMLGLDDGGYNFAYGEGQQMGYLPNNNDFNNINNVNANNTGLDNSVNNNFDNNFNGAATYPIDGTVGANNMYPTMTQHMPQQLPQQGTPMYWNMPNNPNVPTIAGPFMTPVTQGDFPNGLLGAPFTVPSNNGVDGMNGVDYGKDNGFPQFALQTPQSSPGQLPSNPANGNLPPGMMPMTPSPQKLAPNFNSPLSVPGSNSIPSRPVSPSSNQGSTPGQSSSSPRTFACDDCGRVFDQIHKLNHHKRYHERPHECTVPGCGKRFGTRTHLDRHVNDKHSKSRKYHCTEEGCPYSVPGGKSFPRKDNWRRHMVNKHGVHPDHEPIEVIDQPMVYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7G0</accession>
    <name>A0ABR3Z7G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004637</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="443" mass="48356" checksum="0BF42F7A7E544DE2" modified="2025-10-08" version="1">MAPKNRIIIDTDPGVDDVLAILLALSASPEDLEVVMLSVTYGNVPLQGCLRNVVALFHVLEKEMAWRKSTGRTSKAFGGLKAFKPIVAIGAEHALEDEILMADHFHGSDGLHGVHDAHPDLTPSETWKSLFAEGDAPASSNELSFSNYFTPSKTPSYKEILRILKEEPEDTITIIAIGPLTNMALAAAEDPETFLRVKELVVMGGAVHLEGNITPVAEFNCYADAVAAARVYALTSLTPASTMPPTIHGKSKLPAYPAKLSRPLNLTLFPLDITTPHLLNKNFFLEQIAGPEQTGSPLARWCKTFMVGTFNKIDSILGDGSEPGLSLHDPLCVWYMMLRDDPQWTATPKPEDLRVETSGQWTRGMHVVDRRQRSKPGDHTEGFAGVSAKAVVQGETEIAEEDDNVPGDTMGWLSVRRGNRINRMVGSPGEMAFADFLMKQLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7M6</accession>
    <name>A0ABR3Z7M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PBP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052738">
        <property type="entry name" value="ABC-Tungstate_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37945">
        <property type="entry name" value="EXTRACELLULAR TUNGSTATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37945:SF1">
        <property type="entry name" value="EXTRACELLULAR TUNGSTATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP" evidence="2">
        <location>
            <begin position="91"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="37425" checksum="014B3AD0577F8980" modified="2025-10-08" version="1">MEEGPTYRVEFINGASIFEFTSTSSILRPDDYHPSSAPHIVSAAVADVYGNPDAPVTIRIGNGGLGPTGLLKALCSAYLSQLSQPGNSGASDLKFEWICNHSRHTQAALQAGVVDVALTYEREEEDRAEREGWSRRAGVLCHDHFVLAGPRNDPAGLRRLRATTTLSPSAAFRVIADSRSPFHTRGDGSATMHREQSLWSAAGVSPHGGDWYKRLPCTPLEALRTADAEGAYLLTDRATVLLAYHTGEVRDLDVFFEGAEELLSPCSILLRSDETRNEVLGFVKWLGGQDAQAIIEQYGRGWEAGIPLFTPISQAEVAPDDEFAHQQRGRRGRPGASFHRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z808</accession>
    <name>A0ABR3Z808_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="37891" checksum="40F1D3DAE2CD07DC" modified="2025-10-08" version="1">MAANCSVVPSSTPSNSGIAGAGVLLSFIITAAVALSISAALVFSDTWGRAAQQRKASGGSSTPTSSFAIIGRKLLNSYSDQQIVTGIGIQSLGLSQINSLVPYHFFLIWMLGLLSTAVHNAALLALVHDFRRDWVLRWLRQALMFVNLALSCIYGIFVLRELAAGLPQTLPMACALESGVSKNTTVSTGDKSEDTTAAWSGSAGAFQFIATVAVVAGNCIVFILSTWYLHSRAQRFYRIVQIIGLALMAAVAIGVAVRIVLLSQAFGHPSVALSDNGETQWSFGQLLSLLMLLLPLISVVEIARGEIKVAPPVQDDGKGGSSSGDTMPLVEHQLPMGKAGHASFQPTPFMSRRTKSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z859</accession>
    <name>A0ABR3Z859_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein cms1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cms1</name>
        <name evidence="2" type="ORF">Sste5346_004772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032704">
        <property type="entry name" value="Cms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030:SF0">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14617">
        <property type="entry name" value="CMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="363" mass="39578" checksum="930238A19EC4CD03" modified="2025-10-08" version="1">MSGRQPLPPPEPPKPTRPPFKRGGFQGGGKRKRDDGNGNGNGPGLPTDRDNVNGYVPPPSKGPRPKKQRKEKKEGDDADKPKQTPPPPLTAEEKRAKFKAKKQKAKENNKNNSQKHPNAVNEADLDYDLALNRSFSRMDAALSAAYLARQTKRYGADLSEIELADLSVPIGAFVDSSPYEKDRTLENLADFLEDMAPITETGKPGSKGKGKQILHTAPEAKGAPHTIVVTGAGQRAADLVRAVRAFGTKNNAVAKLFAKHIKLAEAVEFLGKHRTGLAVGTPARLIDLLESGALSVAHLRRIVVDASHIDQKKRGVLDMSDTVLPVMKWLSRPEIKARYNTGEAEREEEKPKDAPKPISILLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z880</accession>
    <name>A0ABR3Z880_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="884"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="681"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="911" mass="101702" checksum="8E6D65DE389AA358" modified="2025-10-08" version="1">MDLLKDLGNPEDLLDKIFDRKGTRSCSPAMISTPASKKEIRSPLVRPFSDENVSPLRAVRNSQGPDRSSDSHMAMTVYSTDTTVGRMYTQYQKHILNPLYANNSSPVPVIPHIVRHRDGAVNRLGFVPDDQSSPPCGDLAVRPLPNANVQRFQDEIAKTPGVTPTDSPKRGSLFLSVPTRESLLYPKPLRVQSMRVEGKHTSLHSGTAVSAAGITTDSEEDPFRYDKDAYNVFLHPSKERDVSAALNQISGISSHSRATLCTQGDDLPTHKLSLRPPPIPKEYLEDPFLTGPTRARSPTPESADGFYDTSVIQPNWAVERSTYEVKVVLQDVSSNQNVNSGRRSKFGDGSITTSEKPFSASAQTPFQAGGLYRRDKENMPPSERDDWETVVTTAPGFGSMRLNPPIGRGLEAINSRGAKITGSSLADVSDDNSFRNVRFDEYASTDRIVQHPSGHEDSEESLQIHHISGTKVPVMVPKQRVHRVNGYPQNSSRIYPTSQRSGSEAAAALARKVSSPFRQLSGRRPHRFSPMPLQPPPFKLQKGRKKFEFRHHSQGSDKDPFFTKGGVYEFQGVSSETGHTRSATNDNTVSELDDRLGDGHSLRDSSSSQSSNGTVHSFPFPLIPLPEAARKQAFERATTTESSAADTFWARNAANKKRPHGSEHIHVPERTHQRVPIRFPSVFASSSPRSSHQSNRLKKRRNLPEDLTMQSALSSTTGGGTWTTILPFGSTSNRHGGPTHMLKSAATRLHLDDLARRFQERKKSSFTMGSSLISRSSQPRLYPWDYQARRRQQRTRGTDPELRAIALEEPGCERDLERNGVPLDPEAFITHEGRRRRQNWFYCMLAVSMFPFISVMVYLGKFDSGLSWYSRGEVDRLNTQQRRVILVMMVAQFVFWPIILGLVIWRAQQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8D1</accession>
    <name>A0ABR3Z8D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004493</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="8"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="402" mass="44560" checksum="45AD5DEB6E0ACDA7" modified="2025-10-08" version="1">MTLDAEQLRALQIVERSASALSIIGIITIIVTYFSSRYFRNPIDRLILINAFYNAFDVTATMISLSGPAAGNGSALCQFQGFLMQMFPLADVLWTLAMAIDVFLIVFYQYDANALRRLEIKYIGGITALTFVPAFVFLFVKTADKGHMYGSVTLWCAIAPDWVLFRIIFYYAPIWIVIGIVFILYCMVGWRIVKGKRALQSVESDVIPLDLQQAAEKDDDDDHSTNNTIGLAVSSPKRALGAHTSIHGGIDAASPSSSSHPATHPGKAWSRDGTESVSPLRPVDDFGSPNQYPSSPYQQSPGSSPSFNTHKWQANRSALSLRQYLLMPVMFFVVLMAIWVTPSTNRVLSFVEPSFVSYPLYVAVGATGSLRGFWNGIVFLAVGMRSRQSQRRLEAVRPGHYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAF2</accession>
    <name>A0ABR3ZAF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="79"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="321" mass="33873" checksum="FF98D75B60412262" modified="2025-10-08" version="1">MAEYTESWQKLEEVIGARPVLSGTADEMRVAFAGLLGMLATQYPPLTDDVTVENGSLDNGPSYRVYRPRSLPSGAPLAVYFHGGGLVLGDLDSEDRLCRTLSSGAGVVLVSIGYRLAPEHKAPTQVDDSLKGLEWTEKNASTLTGSASSPLLVIGISAGGGLALSVTRRVVLGKSSVPATRLSGLVLLSPVSLHPDNVPAALKGQYTAYTDLATSTAVVDKAAMHTFFEASGVSSADPDAFAALDLPTMGFPPTYVAVCENDPVRDDGNVVDSILESGGISMQRKVYRGLPHCFWIFPTLPETAVFEQDTVAAIRSLSSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL6</accession>
    <name>A0ABR3ZAL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase II degradation factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DEF1</name>
        <name evidence="18" type="ORF">Sste5346_003930</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14368">
        <property type="entry name" value="CUE_DEF1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041803">
        <property type="entry name" value="DEF1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051833">
        <property type="entry name" value="TC-DDR_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16308:SF13">
        <property type="entry name" value="PROTEIN LINGERER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16308">
        <property type="entry name" value="UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <keyword evidence="11" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="CUE" evidence="17">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="103"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="245"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="323"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="436"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="619"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="750"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="803"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="945"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="245"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="340"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="482"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="554"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="575"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="619"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="683"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="819"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1897624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="972" mass="99648" checksum="DC57BCDAC74C4489" modified="2025-10-08" version="1">MSSEVQSRPAATRGGRGAARGGRGGFAGRGSTRRTNGDAKNDESSLASLEDEGEIGQLKKLYGAKTTLIREMFPDWSEVDVLFALRETDGDENLTVTRIAEGTISQWDEVSKPKKERTKPKATTAAEAAAARPPRREGAGSDKTRGRANVRAVERGGRSARGRSAPSAAANGTRSDAPLSVPTEESQAWDGQKPSDESTPEPTAAAAAPSTTSAAPTSASAPATAAPKTWASMLRQTVVVHPPKVVAKPKEVAPAPKAPTETTDSLPTSSSTTAPTAAPTTSSAPTADAEPESAADNDATPVVKEAAAPDVAVPVVAVPEAAIAPSKDALTESNLEQVDDDSHPPETDTLHSEAADSWDPRAAALAGTSTPISASQQHHAAKPAAVGSGYATTATKATDRGAVRTPSYSRRVLDQEEAVRMPNGREVDRAAVQFGALNFNGADNEDIDGDREEPETRTQPPDESPVAQPRASLPPVAPPASVPDAFGAQKQAAANATPTATSTLPSGPAAAAPVAPPTGPAAQTAAQNTQQYGRYGQAAQESAFGQKPYDAYGQPAQAQAQTSANSQFDNYQGLPAASTQAQQAPTAYSSAAPNEYSQYFTSDAQSRMPQYNNYYQAYGQQAAQGQQDGLQNNQRSYGGYDSLSQYPQSSGASRFGGSAAATSTAATDAQNSGTSTPNPPVAGQPQSQQQGAGAQGQHGQQQHQSSQYQAYSNHPYYASPYYAQYMQYGAFGGQNNFGAPYGGKGGYGNTHHPYNMPSQYDQHSSQASGGFGGASSLHRGAGADNSGLGSAGLSDYGRVGAGQSQTGFGGESSYGRGGASSYQSQAAGQGYGAQQSQVGSQQTGADDLKPYGDASKGAGAGPTPSGLARPGSATNTQSSQSLPPPQSTQQGGYSGYPSHLQQHGAGGLHGSNQSAAGGAGGYGGNQNHGNNPYIGAYGGHNAQHGGHAGQGFGSNNYYNNQQQQRGWGGNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAN3</accession>
    <name>A0ABR3ZAN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Branched-chain-amino-acid aminotransferase-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053226">
        <property type="entry name" value="Pyrrolopyrazine_biosynth_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48419">
        <property type="entry name" value="SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48419:SF1">
        <property type="entry name" value="SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="35209" checksum="482EAB10AB07B164" modified="2025-10-08" version="1">MAGQPIFVATHPRSCSTAFERVFMTRQEDLSCAHEPFGDAFYFGPEHLAARFANEPKLREESGFTNTTYKDVLDSLLNQDKRVFIKDMAYYLFAPRGQPTSVAPSLADQANGVDKQAGDRAANPTTIPLSALRKFRFAFLIRHPRRSIPSYYRCTVPPLVETTKFNEFMPCEAGYTELRQLFDYLREQGLVGDDDITIIDADDLLDRPAEGIEAFCKAVDLDFRPEMLQWDDSASQEHATAAFEKWVGWHNDALASTGLKARTSHKKTPSTDEEDAEWASKYGAKGQKIIRDCVDANTPDYEYLKQFALKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB30</accession>
    <name>A0ABR3ZB30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-Protein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GNA2</name>
        <name evidence="8" type="ORF">Sste5346_004078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF242">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="354" mass="40869" checksum="0AA97DD4F0375D34" modified="2025-10-08" version="1">MCFGGRSKGDEDAARSRELDKVIRADEKRLSREVKLLLLGAGESGKSTVLKQMKLIYSQGFSKNEKLEWKPVVFNNIIQSFRLIYDAMTEFDIEFADPENEKNIKVILVEFELGANDSMPTDYLEPIKTLWKDDGVRRAIAKGNEFALHDNLDYFCEDLDRIWAPTYVPNDQDLLRSRLRTTGITETIFDLGQMTYRMFDVGGQRSERKKWIHCFENVNCLLFLVAISGYDQCLVEDKDGNQMNEALMLWESIANSHWFTKSALILFLNKMDLFKEKLSNSPITEHGFTDYTGPAADPKQVSKYFMDKFRALNRNPDKEIYGHFTNATDTNLLKITMGSVQDMIIQRNLKQLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB75</accession>
    <name>A0ABR3ZB75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="44"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="178"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="333"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="544"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="718"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="876" mass="98391" checksum="15934257C442F0BF" modified="2025-10-08" version="1">MTLHPVLHRIAQPIAVHEFIDALRAAAPPRFPNYGRRVSGRAGMAISGGVDSMALAFLCAQAHKSIHDVHVADSVAGGFLAMIVDHGLREGSDKEAAAVAQAMLAMGHSCQVWPLKWQGHDTNENLAANIALSEFQIIPGPEPESTIRIHLRGLRQEQGTQGLGQGGGPGQGTGPPASALETHARRLRYRTLGNRLMRQGIMSLLLAHHEDDQYETVLMRLLSGHGTNIRGLRGMRAANDIPECHGMYGVYQSGAVDNKQREYRWPTRVQRKSVRSEFQDDIKLAMKQWRLSGQRWPPTGDLLQQWQWLARLHDAPNSAAPPLPPLDTEDMGVMTYRPLLAFPKERLIATCTANNVTWFEDKTNADPTMTMRNAVRYVAKHHTLPKALKKPAILQLAARCDAMSRQHDAESRRLIMRHQVVVRFNSSVGTMVVRLPKMEAKARRRPWNKQKDFYSVVSAEKRRLYLRTIAALAVQRLLAFVTPETNVTPISQLQSVVDTLFPDLVDPSSRTATQAAALDPKAFMICNVHFVPFIDNSTLPANPYSSPPAAAADTSSSSPSSSSSPSSSSSPTYSWHMARAPYHSPERTARDVPTIPVLQYYGVPFNRRINKEPTRWKWAVWSPWRLYDGRFWVRMRTRLPNNLFLQPFDIDHSKPFREALGQGLRGPGRLEAFLATLKTYAPGKVRYTLPAIYVLGDISWALDPQHPRHQKYWPEESSLKHYPQPHPSSSSSFSSSPSSSRSGGRLHNDKYNSYLGLSALVPLHTPWELELPDFYTDPTQGEPGVYRNSGFRTIDMHAWERRLRYQDDIARLTRPDPFRPPGQLLALPTLGVHIPGIENWLQWDVRYRKVDTGVLETLAAAAVEKMYLERMYGGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK2</accession>
    <name>A0ABR3ZBK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">STE4</name>
        <name evidence="7" type="ORF">Sste5346_003975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="67"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="197"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="240"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="39797" checksum="417B7859F1CA5750" modified="2025-10-08" version="1">MDSQRQSDVSPEAMQARIQQARREAETLKDRIKRKKDELADTTLRAVAQQAHEPISRNQMMKPKRTLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLNQNRDGPTRVARELSGHAGYLSCCRFINDRSILTSSGDMTCMKWDIETGTRVVEFADHLGDVMSISLNPTNQNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLFDIRADRELNVYGSESILCGITSVATSVSGRLLFAGYDDFECKVWDVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSWDSSLKIWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK6</accession>
    <name>A0ABR3ZBK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01831">
        <property type="entry name" value="Endoglucanase_E_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040794">
        <property type="entry name" value="CE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037461">
        <property type="entry name" value="CtCE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052762">
        <property type="entry name" value="PCW_deacetylase/CE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37834:SF2">
        <property type="entry name" value="ESTERASE, SGNH HYDROLASE-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37834">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G00620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17996">
        <property type="entry name" value="CE2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate esterase 2 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="97"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="312" mass="32400" checksum="B063C57E3C9ED8B7" modified="2025-10-08" version="1">MSRTGVAFSFNGTAATIGFTSVTGNNSVELVVDGGAPTVISNVDGNNISVTKLTQGTHTVVLHKRSEALFGSLFVGDVTTDGTLVTGPEPTHQIEIIGDSISVGYGLDGTNPCTNTAAVEDNPKTYGALAADKLGADYSIVAWSGKGLIRNYPTGGVDTSPIMPQLYTRYGADDADNSYTFPATWSPAAIVVNLGTNDFAYSGSRDPIDASAFTTAMVKFVRTGIQAHYPKAHVFLMGSPMLSDPYPSAADAQKTTETDALKNATAQLGANAHFVDWPTQGSDVGCDYHPNAATHAAQGDVLAKAIAAAIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC00</accession>
    <name>A0ABR3ZC00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3500 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489:SF1">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="49407" checksum="E8AE54D7E3EA2051" modified="2025-10-08" version="1">MANSSNNDTPSSFRSFLPDLSTPRFTHMRTQDTYEYSNEFITGGNPPWLHGLYLHWRQLLTEPFVGVTNDGKIRPDLFTLQDEEVPIAAITAAAKAVVSGCDDVQRARLSYHIDSHEWRTWSNPEFLLSDKGIRLDEISETLRGKVLSVLETALSPEGYQKAIGAMRVNGFLGDLVQAPAVMNEFSYNFVLFGNGPSEDRPWGFSFYGHHLCLNAFFYKSQMMLSPWFTGAEPNLIDSGPYKGTRILDVEERLGLQLMQSLSPEQQKRTQTYEKMKDPAMPHGRWNHDDQRHLCGAYRDNRVVPYEGILVSEMSPSQIEVVNGIVEQYLLFLPSKSRELRARAIVDYYHETYFSWIGGYGDDGEPFYYRLQSPVIIIEFDHHSGVFLTNKEPARFHIHTLLRTPNAGDYGMALRPLIDRLDQGFVWEDERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCX8</accession>
    <name>A0ABR3ZCX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NHX1</name>
        <name evidence="13" type="ORF">Sste5346_003981</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="358"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="52"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="504"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="518"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="702" mass="75362" checksum="45911FBDEEC5FB40" modified="2025-10-08" version="1">MPNGAMWSMVTDTAVEIARRASEETDSEGGDSSKKEIYASWAIFILIMLLIVAFFTSYILQQQKVTAVHETVISIFAGMTVGLILRVTAGDSIRDLVSFDYQIFFNLLLPPIILSSGYELHQGNFFRNIGTILTFAFAGTFLSAIVIGVILWLYTRIPLEGLSMSWIDAISVGATLSATDPVTILAIFNSYKVDPKLYTIIFGESILNDAIAIVIFESAQKSKNSSATSSGIVSLLKGIGIFLKDFFGSMFIGAMVGIIAALCLKYTYVRRYPKIESCLIVLIAYATYFFSQAVEMSGIVSLLFCGITLKHYAYFNMSRRTQLSTKYIFQVLAQLSENFIFIYLGLSLFTEKDLQYQPLLIIVTVMAVCAARWVAVFPLSKAINWFIHYRERRRGIVNSADELPYNYQAMLFWAGLRGAVGVALAALLTGKDTYALKATVLVVVVLTVIIFGGTTARMLEILGIRTGVVDEIDSDDEFDIEPVGPYVKRNGGFGYNPPRVPGTYAGSPLPLNRLGSSSGSGSGGGGGAGANGTKRGYYPSGSADDGADRRSWTTGMRSPNPMGGGSSLSRKSSVHDLASGERSDLLGYSASATDSEVGSDIDTSDLPPPAPRRRSSPLPPGAPESYGVDMGGASSSSAAAGSSSAAAGTSTPTTHMSATAAFRQLWNTEDPTALLRQLDEDYIKPKLLLDGGNGRGNGGSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDU2</accession>
    <name>A0ABR3ZDU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="681"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="813"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1181"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1229"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1269" mass="133751" checksum="9CA0BC9157A7C57B" modified="2025-10-08" version="1">MPPAVPTTTRATRSRFSSPLHGGATGTADAATSSGSNTGRQAGSSSIPRSSAASNSHSNNGVTNAQKAMMARWLEPPVQSKSSFEEAGFQRHGVFEGMAPLGTLPKAVNVAKRISGLPEEKLFHEASSPASRQAAKQQQKKKEQTGQPTRRAGQQRQPSADDEDVIGAPRQESIEQTDVDEQEAEASEKQQQQQQEHVEDADEQQHQTTSTLNSKKIILKRPSAGKHVPTRIIVGPKRSTRSGPESTVGDAVEGKGAGAAGKKESGPTTPTTPVTPITPGTRRSIIFRPAPGSAKRQGRLSARQQEKQRQKSQEAMEEEADDADQSDQETGAGPDPVQAADVNVSESAAGQSAEPQVEQPALEKPKPAKRPVGRPKSRRSLAAEQKAQKEKEEAKAEAERIVAAEAEAQIEAEAPSAPAPAPASAPAPAPAISTPVQPEQANNADTDEEIRDSDGDSFDSQAEDGDGYGGRADGFDSSFLPFMTPYGIHRPRSDSNATEVNREVTDKVVDIAVEEALRHFRYPTAWALRTLYDEQAGNQTFLTMVEDVFQQTADRETIDTFARMVHEKKKEGKKDNKGCHHFVPPSTENEAAPMHRPIPAPYADLITMDLPQFTTDESGHIVDSTTDDTAHARKRVKLTDEDSELVPPEPASATVPVAMHTFAPPPATVAVDSANRDSERAPSASAPASASASASASASVSRKSSAKVGTPLQSPTTMRTPVPGSAPPKTPTKTPRRPPGRPLGSKNKTLAEKAAIAQMKQPAATTKVEEDVAMATPQPLTESNVTAAATAAATAPPPPSTPPTTRRHLRADSAASSLSPALSLSPPSRHVRRREDDDETASLPSDKGDNDVVMQDAAGPFATSIGWTADTVKRTTEKCEKDQSLENASGNGKDNDSKASALSSQSNNKRGGGGGSADRRRGGPGSGRGGRRRGAGRPPKNRTLAAAGQPAPKSVTKTQPELAPTPAPVPTPAPEPALQPIATRNRSSAKKSPTPLPALISPLSPSSSSQTQQTHTHTTSSQNTHHQQPKRTSAAAAAAAISASAKEEMPAAVEDHISVRSVSVAKRSQNGNSNGKNRNSTAALPSPALNSTDAAPKSSLGKSESDEAGEERLSRMRREARSITNSIGVAPESFTRGDAAQLPADAVSSSARPASSASRGRRGSVPDASSHQPLLETPQPQRQRQLRASTTATRTTRSARKRAFDEVDDDMSPRSGSFPSDDLPSTRLQTPVPTTQQVAVTNASNLNSRAGTPGPKSKKPRVGPRVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE25</accession>
    <name>A0ABR3ZE25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003319</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="44"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="416" mass="44668" checksum="CE1662123C064797" modified="2025-10-08" version="1">MTSLDAYLAKATLAGPERTLPGSEAHYKTFGTESVDPASPRFDRPLSIDSCMWVASCTKLMTAIAALQCVEKGLLTLDDDISTVLPEWKKEDRTILRGFDEATGAPKLEAAQGKVSLRTLLTHSSGLGYAFMNESMHKYIKYKVANGWKIESELLCPDEPIPLLFEPGTSWAYGIGTDWAGKMVERASGLTLGEFMDKNIWKPLGITGATFRILERPDIRDRQAEMTIRTTDADGKAAVGPHPKPYFPEKTSADHGGGGVFTNPRDFFKVLVACVDSSPILLTPASYELLCEPSLSEASAAAFQAFRTASAEAASAAAEKRGTPMAIPAAKRLNVALGGGLNLDDVPGGRSAGTIAWGGLPNLSWTVDRKAGVAMLYASQMLPPGEPLSAWVVRKLEAEIYSGAFFEGAVRLTANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZED7</accession>
    <name>A0ABR3ZED7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone transcription regulator 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HIR3</name>
        <name evidence="7" type="ORF">Sste5346_003555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HIR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1019"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1598"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2009"/>
            <end position="2034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2057"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2119"/>
            <end position="2504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1019"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1605"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1721"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1790"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2009"/>
            <end position="2029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="2123"/>
            <end position="2139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="2211"/>
            <end position="2224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2247"/>
            <end position="2258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2274"/>
            <end position="2283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2288"/>
            <end position="2309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2331"/>
            <end position="2495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2504" mass="279105" checksum="7EAA912C25078A0F" modified="2025-10-08" version="1">MPAFAAINVEPEDNLEDEVDVTRRIQIDDALKLYQTALKFHAQGPKSFPEAEQAYDVLFKSAIFSYPEAATDYDRAERQTDTPLTPGPAFVASLDPALLDDNSTGSSLPQAYYIAYKNHAQFLLDKVRHKARTWRAEGNKGIAVFAEKAVRDDTKNALDEFDAALDRDPSDAELWRRTSRVAAFLRSGRIERYCLEAAIELDDDPAVVEVAPPSLAEGFAGEQLRNQLQDLSDDISLSHPIMVPYLRREMAASLKRYLDPLPWLPNPTKNIALPLKAVSDSESKEKDSVRITIKFTEPSWADLGLALVKSLNEHGISGRALFLDAPKMPDDHQIMQIEIDQQLSSLHQDVPDVDSNDKAAKEVKAEESGEAELEESTKANGSSISDDKEAATAKDSPDNTSQKDANKDGSASQSRKRSQSTAGLPEAGDDDHADTKRSKRIRRRETLAEVAADPNAAFAEQLQPYQEADQHLFRLAKQLLEKVGVADIPALDETIEVSGQTADRISKLQNQLAKDLRSSLITAFKDDRARILLNKKDTPVLGLEAFLERARSGHQHPPERAAFDEMRELRSFIIKVNKGWYTIQDVVYAWMSAMAQSYGSLKWSESMKTVVVQMLNTFDAPIFTRVLGELERWHSHSGAQKAIEDSNSIPAMAAEEIHSLVQMIFELYIDIYERITNPSSAVDATIRTETKLRLDRWMSLASDIARSSPRSDANLTCRFLWASVFSTTLTPGVPRDHILSCWESLRQTLYEEQEKGQKIEVVLPNNAVMPDVSYKAADREISKLTTMDFFLSLFQEELKDPVVIIDKLEPVLNPDSVYVPISDEVAGEQKPISECASTELRDMWKFLRGSNTELRLFLWTRLADAYKEIDYPTKVLSCYLRCIEMVVRDLESEQYLSTPQESTRLQTFMLLLKTIDEMTIQTLHMAVNDPQAFEVIDEEHVRSSATALVRISCMLHVAALHEDEVRIGMSSNASNTQTFHSLQNKLREMQVRTWSLQYSILKTGLKLMAATSAAEVRASAIPSTPGSTPTSSPMPVTPTKTGSPTGNETPLPPVLPSIQVDLADLIGAIHQVVGSRKYCKASNKIFLRLARAELLKMKGIDNWEDYLGQVLYDLHGIKLGVGSFEVQEHGCPIEKLERKNALALVDKVMALASGMQMKDLLKSDLKNTIEQMQQAIGQTRSTSQMIHNLRYFTEYLKRPIHPMRLYEAWKGVVELDTVSATTPDTVLARTGWFFLMGMVALTKFKGVDLNRRQTPGATDDLRVGTQYLRLQLQLTPNRWDAWFRLAECSDYDLDEAVLWSAEKINKDRAELVKLQRSAIHCYTLALSYYHADPNELSENDFDAVHDLYADFGLRMYSSSREPFAMECFHHSQHERWFIAPDHMSTYKKLQHGEMSSYMVWKYASGLFRRALARRAKDWKSAYMLSKCLWKMYQKPIDELHPREKNSHPSIDAIVRSLEKAIEVVSLLPKPRHGQDPVLEPHYKIVSVIDKLVRRGEMHAQVAADILQRQPYAVQHGETVSITNMTEWDDFMVKSLQHLRDKDKSNWQHRMAIRQARILFGDCDLVEDAVPAIEEMEVDKEHNADDTIVIEFDAAADANGTNGASKETKDTDNDAAKAATKSDGKEEPSDKPAEEAKATTESAKDRDQEGSKPEKEADDKEVDDSKDKADGKKDESSKDAAIEKGSKSKYKSKSDKPTKKTPEEPADKVGDSIVVRSSPRVAAKEAEKEAEKAADKIADKDADKDADKMDIDVEPANKEDVDKDAKDNTGTKDTKDTKKVESNGATDIDMAVDKDADKDGEKAVAKAETDPEEAVRNEKAQAAFSVLRESMFTKTMVMNVWKCDAERPGRHHVFTEQYIRFMTRLLVVLDDRINLEALLRRIRKKGADFYHFNDLWQTCVVSYLRLLRKYYKIPHGADIAFKNVTPEEFEIYAERISKWVEEKPDMDHHALNAMREAIEIKKLNAGLLKGGSIDDLISDCYSAIFADVGRTLPGEDPTKIVEERHRKLREEAEKAEKAERAERAEKEKQAEAASSTTAAIMLSFNLLSDRNNGADKDSINGISRAGSEAPGGLFASEKMERTGSGMGGDHPHRRGRAPGVRRADILRKAEQLSTLLGDIIAKTGGPGASSSGAGGDGHGSSGTNMQSRRGGDGPGERGGMSRRSTRLGSSSSARNDLNMNSVEGLGGGGGGGDNKDGDGSGNDGEEGVSTRGRTRSTRSKSRHRSAGPGQNGDGDGANDDTEMKDVDERDEDGEDEEDGGDVKNNNSKDTKKSGSSEAGSSPHASANDWADDESELSELSDVPPDYEDNAPESMLFPNLRRSEPAETADNSAAEEEEEEEEGGEEEEEEEESGAEQEVGEEEEEEGEEEGEEGAEVEEEEDEEGEEDEEGAEIEEEEEEEEEEEDGATAIEGEEGAEIDEDEDEGEDIGESGEEDEEEEEDEEEGDEEEEEEGEEEGEEEGEEGDDEEEEEEDEEAEEDDTVEVAGEDVEMEDDDRESSVALVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEH6</accession>
    <name>A0ABR3ZEH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Trifunctional dihydropteroate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FOL1</name>
        <name evidence="16" type="ORF">Sste5346_002998</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="15">
        <location>
            <begin position="201"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="491" mass="52608" checksum="3DA7DA463D6B3563" modified="2025-10-08" version="1">MTSTSPAAACCQSAGGPVNKKKRAYIALGGNLGDRIGWIEKACREMDSRGIRVMRTSSLWETEPMYVLEQDKFANGVCEVETELEPLALLDQLQDIERTLGRKKVIDKGPRNIDLDILLYGDETVNHERLIIPHIGIPEREFVLRPLAQLAPNIPVDPTRPWKLVQDYLNELPPQPEPLTPLTPFGQKHAPLQALRSNRGTTVMAILNVTPDSFSDGGKHSTSDTASLAALAETVKAFVVAGATVIDVGGQSTAPGRPQVSAEEELARVVPAIKMIRADPAYDAIAISVDTYRASVAAAAMEAGADMINDVSAGDMDAEMLPTVARLGATVCLMHMRGTPETMSKLNQYGASEGEAASTSASSGGASIIEAVARELLARVEAAEAAGIRRWRIVLDPGLGFAKVGDQNIDVLRHLAELREWPGLEGLPWLVGSSRKSFIGRTTGVATPAERVWGTAATVAAAVQGGADIVRVHDVREMAQVVAMADAIWRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFI7</accession>
    <name>A0ABR3ZFI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_003046</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="142" mass="15462" checksum="E193D58FCB0F992D" modified="2025-10-08" version="1">MGTANKKTLTKTRRKTRDVDEIANDLLSPAHLDRFKATKASEDLPGLGRHYCIACAKWFETEFALSKHQLAKPHKRRLKQLAEGAYTQREAEAAIGLHTDNGPQTKIYSKPLSVSTTGTTAGETDVKAPTALSAPADAIMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFX6</accession>
    <name>A0ABR3ZFX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">sterol 22-desaturase</fullName>
            <ecNumber evidence="7">1.14.19.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ERG5</name>
        <name evidence="9" type="ORF">Sste5346_003004</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.41" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000249">
        <property type="term" value="F:C-22 sterol desaturase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd11082">
        <property type="entry name" value="CYP61_CYP710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="535" mass="60527" checksum="46CEA65464AFE4BC" modified="2025-10-08" version="1">METVNATSFASPLAHAKYVASALPAQLEPVINAIANASIWQILLALLVTAVLYDQISYIWRKGSIVGPAMKLPFMGPFLQSVNPKFEEYYAKWNSGPLSCVSVFHKFVVIASTRDMARKVFNAPSFVKPCVVDIAHKLLGADNWVFLDGKAHIDFRKGLNGLFTRKALECYLPGQTEVYQQYFDRFVQVTKDHGGKPFPFMSEFREVMCAVSCRTFVGHYLPDESLKKIADDYYLITAALELVNFPIIIPFTRTWYGKKAADLVLHEFSKCAAKSKVRMRAGGEVTCIMDAWVKAMIDSERWREAEAKGITVEGLEKPSPMLRDFSDYEISQTVFTFLFASQDATSSACTWLFQIMAQRPEILDRIRDENLKVRNNDPNGTLNLGQVESMTYTRAVVKELLRYRPPVIMVPYLAKKDFPITETYTVPKGAMVIPTTYLALRDPEVYTNPDTFDPERYFSGDAETKGAKNFLVFGTGPHYCLGQQFAQLNLALLIGMASLQLEWEHHATPLSEEIKVFATIFPKDDCPLTFTKREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGJ5</accession>
    <name>A0ABR3ZGJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="379" mass="41934" checksum="AF6157CFD26B0115" modified="2025-10-08" version="1">MDYSIEATPPTTADRKERILDRKHSLCMSPSPWATAAPPTPQDSLASPCQSPPTSPSLQLAEPVSPSPAMLDEDDNILMHDSGSAARTTLIRRSTPTLITIGPKPRPAGRENRDNREIRENKNENRMQHWLSEIPPPVSPQERYIQGLNPAVDHPLHPRPLRAVTPRQARYLSSTDITADDDDALSLSCEKLAIDSSDKENAMIHSRLRALGSPPEITPTNVLGEKVGFGTKKRHMPEDVGDVLARKRTRLLDPVRRFSQRLSSTLAMSSGSEEERRTDSEDLSPEEAAKQSEILYKFSRLSKTPSNSVRSSLSKRYSGTLRSQGSNTIRRMISSKMPPPMPPPSRDGQVGFWTEGRPDMIVNVAFIGDARVGKTALIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIG4</accession>
    <name>A0ABR3ZIG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 8">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002712</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="234" mass="24790" checksum="EEF9746769FD2205" modified="2025-10-08" version="1">MAANKQSSFSYALSSNAAWAGYKAHQNPSFFPNLASGQSPQILWLGCSDSRCPETTILGLQPGDVFVHRNIANIISPTDINTSAVIEFAVVHLKVKYVILCGHSACGGAAAALSDSRVGGVLDTWLTPLKAVRSAHSEELAAIRDEKARAVRVAELNVEAGVKVLLSNVVVQEAIKERGLEVHGCLFDLASGRVRDLGYGTGKSAGMFGADEEIVRGNHGMLVFRAGNASMAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ4</accession>
    <name>A0ABR3ZJJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="331"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="190"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="447"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="626" mass="68714" checksum="FB7031FC9B352456" modified="2025-10-08" version="1">MSNGSDDYNSLYPEPPQGVFASPSMSTNQHMSPSRFFPRTQQNFLPPTSGAFDDGSNGILYTTDLPFTSMFGDHMSPTMYYEDSEMLISSSSLSTASGPSAPSSAVGSPRSHHDIPTSVPEWPAPQVLSVSPNIVSQGDFFGPGEYSYTNSHMDEFAHFEFPQPKSFIADPTILHSQVRTMGMPTLDAYPQMQPPNPVAYSASPRRSPELKADSISPYATGTGAYPQFSSPYLTPTAMDDKRSQVSRGSRDSRSSFSGFSADQASSDGESKEKCPDPTCGRRFKDLKAHMLTHLTERPEKCPIHTCEYNIKGFARKYDKNRHTLTHYKGTMVCGFCPGSGSPAEKSFNRADVFKRHLTSVHGVEQNPPNSRKRPAGSSSANVQKLSTYAPDATGKCSTCSQTFSNAQDFYEHLDDCVLRIVQQEDPAEAVNASRLAEVENDREVQATLEKNQVSSAVADSTHDGDDDEDMDEEDAAGDDESPKDGSFRGVSGSPKKLKTGPANGVQKSRGLTHSRGGVPFTGKPRSRRSRQNYPTSWGFDKGQMTMRKRVMTVFEGPRRLAKDDMMLSTEHEVRLKLSDGKAYVTDLDVQTLKRAEGFLTATDEEKGPWISDDPTAEQMKQMQAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJP7</accession>
    <name>A0ABR3ZJP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">I-AAA protease yme1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">YME1</name>
        <name evidence="16" type="ORF">Sste5346_001999</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048438">
        <property type="entry name" value="Yme1-like_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21232">
        <property type="entry name" value="Yme1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="342"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="751"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="758"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="779"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1900938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="789" mass="84872" checksum="3DDB85A821572881" modified="2025-10-08" version="1">MTHTSVMGASPFMRVAFNGVAMSGASRLQTRTIATSALNNLFRSNIAAAAAGQQMRFYSGASGLTTSSLRASTGSPFASSRTSMLFTQAAQHMMARTTQQQQRRSIVLSGGISRNLLENRESAANRNPSSAAAQNAFYQVLLKANMPMIVIERYNSGRFASNEATTEAYHRALGMISSTPGAVPSSVADGSAVVGGMSGSGLAANNSHLNATQLQAVGQAIAAQHRGASIAVGKGAQGTGAKDAPIHVVVDQPIGDVLFRWIKFVLWFCLFTYFSLVVITMLIEGLNTFKRPTGRSDNEVKAESQKTRFTDVHGCDEAKEELQELVDFLKNPAGFSTLGGKLPKGILLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEVYVGVGAKRVRELFTSARSKSPAIVFIDELDAIGSRRNSRDAAYVKQTLNQLLTELDGFEQNSGVIILAATNFPELLDKALTRPGRFDRLVNVDLPDVRGRLAILKHHATKVKASKDVDLNSIALQTSGLSGAELESIVNQAAIHASKAKSAFVSKNDFDWAKDKVIMGAERKSMVISPKEKELTAYHEAGHALVSYFSPSAPNKLYKVTVLPRGSSLGHTSMLPEMDKYSYSVKDFLAMIDVSLGGKLAEEIVYGNEMVTGGASSDLEHATSIAYRMVTQLGMSEKVGPVQFWSRYNQLSSETKSVIEAEVQKTLFEAYDRSRKLLVSKRKELDLLAKALLEYETLDKDEVLKVISGQKLTDRIPVPIGPMLVPKTPGPLDDPMPPGLGPDSEDNKAPPPPPQTATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJQ2</accession>
    <name>A0ABR3ZJQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RDS2_1</name>
        <name evidence="1" type="ORF">Sste5346_001982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="159" mass="17827" checksum="9789B9138385AE98" modified="2025-10-08" version="1">MRFIVNKLHQADSCSGEKLIKYYRCLFQAALYRDNNAAFQVLEEVKEMIQVGLDSETMVSWPEDELQFLAAISFNEGIDWFAGGREDQARQWVLSAASLAEQCHDGGKLKDLISSRFGLLNIGDLDIRESIESDNRDIQDDVVDAMAFDDMAGGVDPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJY0</accession>
    <name>A0ABR3ZJY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF78">
        <property type="entry name" value="PROTEASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21322" checksum="42CF4C096488A6CB" modified="2025-10-08" version="1">MADRFSAAVKTAFAAIEKKDSKSSTTPATLRLTFGNQADSAADVVVDAQNAGTFVTPTQATKEPQLALAAASATPGTKYLAVSLDPDAPFPSFSFLGPILHGVQANLTAGDAVDGWAPLTSSVAPAVDYIKPGPPSPSAAHRYVFLVYKQPEGVDDSKIREAMGWATEGPAVTRMGRMRFDVGDLEAKLGLGEVVGVNYFESSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK81</accession>
    <name>A0ABR3ZK81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="57212" checksum="AA4F106991CDE521" modified="2025-10-08" version="1">MIDSFESNVLRLLQAEQEQKTTFTADAKRITDRCRSEHGDNKKKTSNGEDVEMTDVPSSTTATNGHSTAPKSYFCRPCYNDILTLLHQTYASPAQPQWYASQQTSFIAGLDKLLDDVRNLKTPLSSADEWISQQKQTWLRSQLQDAVGVKTLAKSLEAEDDKVALEAKLSDSTVQLTDLLGAVTIQAAGQVNQGKGERERERIVADVQTASKKLRQSTDNTEKSTIYRDNLFPGDVVSDLPAVRNIESKLLKGSVGLDQGLADLLRDVHGGEDEDSRAAQIEKHQKRLAELKRAKAAHEAQKLKKMKPVDVPYFLQDDTPCATCNTMSDPQKSPFCQVCFLEVDYCLRENQTVWCSTTCMKKDYAAHLAANHACAAGDRCARKLDASRESHKSDTGAAAARQEPRYYFCRECVLSFSIGTVYCNDRCASRDFQRHREKVHLPNREMRADSRDDRGDLSYSSARKVAYTAADITKHVLSLDEALASCQKKHPDWDLTTTKVKVVLPLTSTGTGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL64</accession>
    <name>A0ABR3ZL64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="47"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="352" mass="41365" checksum="A1F86973804B7B37" modified="2025-10-08" version="1">MLKGGMLRPQIRPLKVDYNDPSEASGGIPEPTQEYLQQANQDWTKLEKAQPLLIISDLNGTLIFRRDTRTRPKDFVPRPHALQFIDYMMTHFWLGFWSSARLNNMASFVDHLVHPTRRDELAFVWDRSKFGLTPDDYERRTMCYKRLTRIWNDPEIAKTHPDYASGGRWSQANTVLIDDTYEKARSEPYNLIEVSPFEGGLSVPNMELTEVHDYINMLAFQSDVSAYMRIKPFRARNHYNTPPTVNIPAVTENEDAFRFMNALRKKHMYDFQSPLQRKGEHRGKAGKSRGKNSPQKKPSKEDFDSSGQVEDNQEMNSRKWQKQQWKTDKPPAPKWEDTEEYQWERLMQSKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLJ1</accession>
    <name>A0ABR3ZLJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001961</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18966">
        <property type="entry name" value="chromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="222"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="465"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="232"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="382"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="494" mass="52969" checksum="9FB6F2F814C57CDC" modified="2025-10-08" version="1">MARGNAVKSEPSASATTEGTDDNTSVTSTPYDSEDPDAEYSVEDILAQDDDMDGVTKYLVRWTNYPLEKCTWEPEENMGHELLEDLWEEKKKRPDYKPFDLSLYLGALADKEARHLRRNLKRKRLGLPETPPFSMDDEVVMSEPVLGTETSLDAADAITGQDIVSAVAGLSSAPGAADTADLTSAAELASENSISAQLITDLTNDSGDDLVVLDAISAPATPKLKKKKKKKKEDSTKEKADSTKDRPPTAEKSASKKDKTMSEKDRTVPAKIKVVFIKKTGAVSKPALKDEGKDAVEAGTPRPTSSFSSALVTSGDLPRKPKRIEKRKSTDGEKPADNTDVTKALKGPNGGARRVSEPGPSAPPTANNKEPATVRKPGQGPETATRNPSAFSARRSATTPQVQVTGNAFNSGEKIRKGPTLSSAMVDPSKPRQLFTKRRTLRQAEILQRDKVDAAIEPSLLSGLFPISKGPPSTPAASSPKPPVSSPGRDQSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV6</accession>
    <name>A0ABR3ZLV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001839</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="22"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="536"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="575" mass="60613" checksum="45C7079F696A8994" modified="2025-10-08" version="1">MKKEPTIHDQTNLLPKNRLLVVFPALACALLITYIDQQSIGVVLPTIGPDLNSASTIVWAGTSSLIANTAFQVLYGRLSDILGRKYLLLGCLGLLALGDLLCGFAKTGTQLYAFRGMSGVANGGIMALVMMIVSDVTTLEQRGKYQGILGSCVGLGNTIGPFVAAGFARSKATWRATFYFISPLAVAVAALLYVLLPPQAIPADEPWRTKLAKVDYVGILLSAAGTIILLVPISGLGTQFAPDSAMVISMLTIGGVLLCLFMINEWRWARLPMFPLRLFKNKALAAMLIQNFLIGIVFYSLLYYLPIYFQTARQYGVLESAALVLPIVIPQALASAASGQYISRIGRYGEVIWLGYGLWAVGAALQCLFASRNFPIGAVAVILAVQGTGVGLVFQPTLVAAQAHSPKQDRAVVISARNFIRALGGSAGLAIASAVFSNTLLSSLPTALPASVRSSIAAAIFAVPDLSGVSDPVVRQGVLDAYSHAFRNICILWAAAMGTCLVLMVLIKDKGLARNVDEKKAGAETAVATAPVVVEGEAEGETSSTEVSENGGGIDGAVEDTVVATVDVERADEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM19</accession>
    <name>A0ABR3ZM19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bax inhibitor family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF112">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37315" checksum="C87D32613384F27F" modified="2025-10-08" version="1">MGPAALRRLAPQAAKASPSTLMGMRAFHQSAVKNSFFTSRTTITNATKKSTTHSSTPASSLLARLAGASRSYYQQTQQTVSQASPLRKLLVGGAIFGGTLMAVNLVFNRETREDGGMPLYEREYLNNTFLHTGLGIGIIAITARAMIQSGFVFRIMTANPWAVGIGGLALSFGTMIGTRSIDPDNYLPKYALWTAFNATQAAFIAPLMAFAPGALLARAGLYTVAMMGSISIVGATAKQEKYLYLGGPLLAGCAIVLASGLAPLIIPATAVRTLAFTENMWLWGGLAVFGGFTLYDVQKVLHHARLAERGVIKRDPVNESISLELDFLNIFIRMVQILMMQQNRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZME7</accession>
    <name>A0ABR3ZME7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001742</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF2">
        <property type="entry name" value="ALPHA_BETA-HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="15"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="280" mass="30449" checksum="B37B23C0A944E0FD" modified="2025-10-08" version="1">MWITYDNSRPPDIVVFFVHGGGFVLGSSHFYLEFLLAWATLLIDGSPGDEKAASFSNPAIFSLDYTLAPDAQFPAQIDEAAHAYAHVLSTAAQGDPSRVVVAGDSAGGTIVLSLLLQMSQTPSSPSPMALPLPGLAVLISPWVSLSSHRYRRSANDYIDAESLVDYAALYAGRAPSQKNKASMIDAILSPGHCNEAKWWRRACPYRGIFVTYGEEEVFAPEIRAWADRLQPDGVDVQTSVDSGGLGVHAWPVASLFLARTNAQRFEGLRRIVGEIKRRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMJ9</accession>
    <name>A0ABR3ZMJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="283"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="509"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="746"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="761"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="807"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="934" mass="100732" checksum="92FF0858695AAE34" modified="2025-10-08" version="1">MHAEQQPRQRDGGPFAGPLSPAASASAPSSSSSTVSVSGTAVTSSTTASNSAKAPKPKRSSVACRRCRRLRTKCLQAEGTNDRSSHQQNNRNGPPPCLPCREAGPDVTKECTYATRGDNADRRFRIKRISYGDVMIQPSSSGSVPPSASVSVSASRASSVSSSVNPLPAPQRMATTTTAVPMLASPVEDDIETVDNDDDEDDEERFIRGPLIRSRRQNSSSSHNNHFHHHHNSHGRPSHAPPPIPASPRRLQVYAASDDIWNLLPPHAELLAGCRVFLATCLQVGFIPKALFLEQMETDPASVNVFLLLSILSISARFTPELCARFRNDGKAAAEFFMDVAHVVTADQMWHTTLENTQAFFLLGMADWGRGARDRSAIHMGIAVRMAGMLRLHREETYKLPAHLEADQVVDAVVDAERARRTFWCIQNHDNLYTQANLPRSFAKSDITTLLPGEETDFAFGRVPAQRAALAGTVPALRDPSLTSLPTQSLFSTLIQAHDLWGIIARSTRAGEGEDSGDDNSGSGSGSGRASEIDDDDAKPWLPHSQYRHMVSTLQAWEAGIPRAHTWTPWNLRGYKAEHVDMAYLSAVTVTRLNNIVLRRTYLDHIVKAMLREGPSQQEGTNDDGAPPGFWEQVSYELFSNAWQLYEAVDVWFSSRGVHDGFPAMLAFCTYVCGSLASHLYRWPQLCPRLAPASAATVLNRSIEVLSTFEDKWPTASQWSSVLRQVAGQTVFPGARPVDDVRSQEALLNNSPGGTGQTTGATNESPAASTAANNNGANGNSNVAGSSSSTQGYSPQAMRVAPRRSMSVSASQQGGGHASSMVPSNHLPPSLPPSAASAGLSHPLPPMVDMAANNHLHLLSRAAAYDSAALAVGVVGQGMSTAHMTTNMMPPPPPTNGAGPTATFDLTDPFADPFDFDFTDIVQGYMHLGWAGWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNI2</accession>
    <name>A0ABR3ZNI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_001236</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="776"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="812"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1081"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1473"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1508"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1534"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="13">
        <location>
            <begin position="1777"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1835" mass="201434" checksum="135DBD4E59FF7EDD" modified="2025-10-08" version="1">MANRMSMYSLASEGPRGAAQQSSQVSTTTLLNAIHNIYLSSSPYHLDAGTSLVVNTWLTANQPGAEGQPGGTVDAALAMRAWEHARRRAEDGCIILGSLHSSAPSVLHPFLASLPLDIPSSLFKSLEAIQPFLRCVTPYNPSTSLQTALGVTLTLNLAGNLTAGSIALSQGGIDTLRGLLKVPSEKGHRAFDVFYYLLTSASTPAEREFLGLKSAADYSLLSRSGTYDPPSYLPTADDAAAADDFRAALKEIGIKGSAHRNLISILAGLLKLGNTLDYDVDEEVLEEVCDDVSGLLGVEPEVLARGCSTEDRSIFIGGLYEALVDWVISKANAAIAAQMTRIRDGDESVAGGHGARTPTSDEDNGDTVCLTVLEIPDPVLGKALSLRGIFDDTLGINSEMKQDGVDVATAGTSVLREMENAVNDVAPDLGIMTGPAGRERTHILEKREELLEKIVLSADSDGFLKSLLMPEEGQGVNLGRAGRLDLATILGSSRVWYHLSVHPTDESPASLAALPSVNSAWSAGTVSRQLRAWRLPEWANRRNKHLDFTADFDHDEFTQRYASLGCRDGRDGIESWVLERGWSNGEVVVGTERIWMRENAWWEAESMLDLKPESGMGMPGMAPGLTPMNLPQGMESGYSANGSGFFQQPMMGDGGSNGSQDQLLIHQHQRNASQGALSVGPSPLGPASVAGMGAMGGMGMGAGMAPSIMGASAMGGTHDAAARERAMKGDYGLGLKGDDMRGQLFYNNEGEFIGLDPELANGKTITSQPITTSRRVWVAFVWAMTFWIPSPLLRYVGRMKRPDVRMAWREKLVLCMLIFLLNGILVFWIVEFGRLLCPNYDKAWTTTELSTHQGSNDFWVAIHGKVYDISKFWKIQHSDIVGRDVSSTNMQPLAGLVLDPYFAPPLVLSCPGLVTDKTLALSFNTTLNDPDAQHTSGQLQTVSSSNLHNADWYTSTFEPKIKAFYHGDLVWNKKDITTQGEDNNYEWVIYDGSVYDLSNYFYTLSLMNNLAQYKFLNSDLTDAVKNAPGTDITETWNNLIASAANNNTAKASIANSMNCIKNNFYVGLPDFRKSARCQVDGYVLLSFTIIICAIILIKFLSALQFGSKRRPAPQDKFVICQVPAYTEGEDSLRKALDSLTALQYDNKRKLICVICDGVIVGEGNDRPTPKIVLDILGVDPKVDPPALPFKSVGTGSEQLNYGKVYSGLYEYEGNVVPYIVIVKVGKESEQSKTKPGNRGKRDSQIMVMSFLNRVHHRSPMNPLELEMFHQINNVIGVDPELYEYLLMVDADTCVREDSLNRLVAACANDAKIAGICGETSLQNEERSWWTMIQVYEYFISHHMAKAFESLFGSVTCLPGCFSMYRLRTADRGKPLIISDAVIREYSDCIVDTLHKKNLLSLGEDRFLTTLMTKHFPYMSYKFIADAYCQTAAPEKWSVLLSQRRRWINSTIHNLVELMWLKEMCGFCFFGMRFVVFIDLFGTIILPSTCAYLAYLIYSVSTNKGAFPLFSIVILSAVYGLQAIIFILKRQWQHVGWMIIYILAFPIYSLILPVYSFWNQDNFSWGNTRVVIGETGKRQIVAADDEGFDPRSIPLQRWDDYATINNLPGRRGGGAANEKGMNVHEGMYDDGYEMDDMKSMYSSVRQPSVLAGLGARGNSFMPPQSQTSPGLYGRSSTVPNMMGGAYSDHPLQHRQSMMSMGTGIQRMNSPYQDAPLGNSRTMSNLRAASNTSPALGGGGLRASTSQLGFGGGARQPLGASEAAHQSVMSFDFQRGNVGPDDGMIVEAIQAVLREVDLDTVTKKQVRALVEQRLQTELTGERRTFMDRQIDNELANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNI7</accession>
    <name>A0ABR3ZNI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002136</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="222"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="469"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="575"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="759"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="575"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="831" mass="90796" checksum="CCDBBF6A404E3AF5" modified="2025-10-08" version="1">MHVKTAGCITCLTINRGHYKPQAEALAKKVRLLEEALAQSRAANQELLAERQQMQGQARLLDVASTATSVGLAGVNASQQSAMRMDIDDTPTVFTVPAPAPVLLPAPSSGIAVPSLLSQSLPATSTVTSTEPSLMPPPSTQIAPQRVSHDNPVQLVMDHGNIVFSRAASPIEQQESRDDQQPLPTETTTAAVGIPFPFPSDRPRLCCCADLDLTPPLVDYLLGLFFHRYQMMLKFVSQEDFMRKHAASSSDGTRHNHHNHSPLFLAMLAAGVRYSTRRDVTARFLLANGENKLATAARQAVEIEVGRPALATVQTVLILCEVETSLDHQMTGYMYSCLASKMIYGMGIDLGQIAPAVRETMSAEEKAIRHWLVWAASVHDQFWSVFLRRPLAIKNGSLQASRMVWRNTGSGLSPLTPAFEDEVNDNLMDLMILAREITDALYGASNTISNNATGSGRQRTELRFDEQQEPMGNNTHDQNDSTSPPCSPPYDGGGLPSALYEQAAQRHACRQRPDVALLDARLGSWFNNLSDRVRQGPINGHSSYHYLFILHLHYNATKIMLHRTRAFSAQATPLQGSDGVNKSHASVPVSSYPLQSPVTPPASSSGDANTPGLPPQQQPAMNFVDHATAQSIATLGRASISMARLFESFRRRDDVRMLQSTGVQWAGMASEALTWYIETLPIDGAIEAVAHLQSLARTLKDMAKTFRPAVYPYDRTSHAIQMFQARMDSSVESPRLESVTLATGRASSRTPLPDLTWAGHGYSGPSQHSHPVSTPRPMPSLHGASAMTIPRAPSQPREPSAPFLMPPGGGTNPLWSWADQDPWDWNDLLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNL4</accession>
    <name>A0ABR3ZNL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF201">
        <property type="entry name" value="MFS AFLATOXIN EFFLUX PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="553"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="577" mass="61408" checksum="6D54B4E98656B592" modified="2025-10-08" version="1">MESRPTTAAVDDLKKSSEDQHNNGNDNVAKTGGDVEAAAEKADEQTFPPMRTVIVVMMALYLAMFLVSLDRIIISTAIPQITDEFHSIDDIGWYGSAYVLASCATQLLFGRFYAFYKNKIVFLAAIVLFEVGSALCGAAPNSTAFILGRALAGAGSAGVMAGAIVITIPLVPLNKRPMYQSMLGAIFGVSSAIGPLIGGAFTTNKHLTWRWCFYINLPIGGVSIVLIMLFLHLPQPPREHALPALEKAKRMDPIGTLLFTPAVVCFLLALQWGGNTYAWNSGRVIALFVVAGVLFISWIASQAWLGSDYATVPGRIIKQRSIMAGVTFSMCVGGVLLSFSYYLAVWFQAIQGVDALQSGIRSLPFVLALVVASIIGGGMTTRFGYYTPFAILCSCLLSIGMGLTTTLRVDSGHSKWIGYQVVGGLGMGFGMQMSSLAAQTVLPGPDVPVGASLMFFGQGLGGAVFLCVTQSIFLQQLFKDLSSVMPAEAARQLVNTGATAIRSAVSSDLLPATLVEYNKALTTAFYVPLAIASFSIIPALCFEWKSVKKAREAAAAEQKPVTDNAVKEGGDESSNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPB4</accession>
    <name>A0ABR3ZPB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="667"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="675"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="745"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="786"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="920" mass="101341" checksum="2F7BA617BE9AD46B" modified="2025-10-08" version="1">MDTYDDSSSSDDDLRDESPEEAQQQQQTALEPLACVACRARKLKCDRTKPACSRCTKATDGTVCVYPESRRKPMFKRRNVKDIEARLAQVEGLLKEAPSLDRKRSAADETESASGRSGRNGTGLFSVITEAEIGGGRGLNDGGPTPCAPVDEDSYSTELMDLGMSEAPPPYEIIEALHTAYFANQHMFIPIVHKTRYLRAFHSAPHLRPPMGLQYAIWAMSSQVYRKYSHFHDAFYRRARQYLENDEMKGHGEHFITIGHAQAWALLAAYEARRLFFTRAAMSCSRCVRLVGMMGLNRLDDNTGGDRLASTLQPPSDWTELEERRRVYWGAFCVDSHASISTGWPTLINANDATTHLPSSEDAFARGTPQPSCTLDNIFSGSTYSTFSSAILVCHLFNSILLHVQLKPSDRPEDFEYGPFWERHRSLDTKMSSAFVFLPERYRLPQNFQDPVAVHTNLNLHAATICLHNAAVERAEAHNLPESVTKNCYDRMFTAAQEIVNIIEKTSHMAGSYKSPLASLSLYCATSVFIYQAMMHEKNQTQNTEAAEKAAGHIEFIMHCMDNGRTNNVTRLLLHQAIMDVDRNGLTTAKHFSWFKRYANRAVDAGHYVPVLARSAVSRHSWQQPPMAGRLPLINKHNTKVMKSQQCCTVGSTNMCDSCRKKMEADQAAGRLPPKNSNAATTNTNGDLNKKRRRLQSPEAVEVPTMDAFQTHYGGAFVVLPRRAETVSPAPSDVSVGSSIHTGQESSSNGESGSRPSVSTQGSLSQLGISSLPGIIPPGVSLVGGQKKQQQQQQQPQQTAAAASATTNDFFPSVSLPDLWTGTSASVVENAGLGDAAAFLGMPSADNDQCVPSSVTLPMDSSFLYNPLDEAVTTCLDEATIQEIVSGDTASQMESNDPWTTFLQAGDFDSTDWSTIDHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPK5</accession>
    <name>A0ABR3ZPK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046784">
        <property type="entry name" value="Eap1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20566">
        <property type="entry name" value="Eap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="587"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="889"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="916"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1069" mass="115388" checksum="CFE422824A91EB39" modified="2025-10-08" version="1">MASRYTAEALLQLRQSPLCVKPPGLPPAEQWMGPVPDNTRVLTTGIRPVTTDRAKTNEGTFSLDPANRRPTGDRHNPRNRSNPEDIVLRPPKMSFTSASSIRTLGNKTDGNDKPFRDSDGRDRFGGRTRGEQSEASNSFLNTSNFGGGNPRSNNTREPRNPDYRRRGDTDQDNEGWSTVKPRKSFGHDGAERFHSRMHNGGSGGAGVGGGGGGGGGGGGADRYGRDDRKPRDRDDADGPGRDRPRRNFDRDGGDDNNDGPRRNGLPSRTPWGGNSNTNNANDDRGGHNDRNNDRNNDRNDRNDRQGQRDRLDRTRNWREREPDSQANDNFRDGRNHDRNDRNDRGGYDRRWDHRDRGDYFNNQRQERDPEWMDEAAFADDVPIGGGSSGGSLGGLGGLGSPSGGGGGGGGRHTEDDLRRFMAEMKGRDAESQKKPGDSSAAGDTKKTWRNEPALAPAVDPGPDRFFEQFSKATKPDDSNLSEADQAALNKLKLNKSSKFSSFFSSQSQTEPPTPAAAPPPPAPQSPSNSGGDAIHGGNFANDGQNPNNGNLLAMLTSQTQSPPAPSGPPTNADKEAFQVLLQKLHSTHVGGSSTTSPAAPPGISIGNIPGPSNTATPPGGGLAFQESPSSVSNPSVPRDGRQPSGFTSPDPPFPQGQPLPGADRRNDPRFQGGVPPVGPQASLQELLMQRQLPVSTQSPSAAARNDQVLHELLLQRQQQAANQEGHPRTGPPSGGSGGPGSNSGTPNAQTEFLMKLMQSRGPDPRRNEDPMMRMPQPQKQVNIPSVPDREAEMAEFARERDRINMQRQQQQQQQQMGRPPQGMPGMFNEEQFHRQEAEGRPPQQPTQILQRPPPPGLEHNMHGPLPPFLQQQQQGGGRPDGGAGGNGGRMPPQQGPPQGQQQQQGPQQPMIPPPGLGSNHMPNMPNMPNMPNMPNMPGMPGMHNMPPNMPPNMPPNMPPNMPPNMLNMPNMPPNLPPNMLNMPNMPPNMASMFPPNFSPSGPFPPDGIPSGPPRNIPPPPPGFFNAPPGPPGFMPPPGMNFQGPPPPDFPYNDGRGMPPPPHGIGYRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ86</accession>
    <name>A0ABR3ZQ86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001288</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050334">
        <property type="entry name" value="Molybdenum_import_ModC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514:SF4">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="103"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="390"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="683" mass="74712" checksum="430116EB6CC844C6" modified="2025-10-08" version="1">MPSLTGVRPPIIRIAKGTFYRHHPSSVPVCDPSGGSSGTAHHNPPLFSDLDFELPSDDTAHGGGAGLGPLTPHNWCVVGPSLAGKTTLLQAFRGQHICLPPTARSYPYLATDSVPHRLKSASRAIRYVGFDADGGGSGLGPATSAYLSARYESRREKTDFSLRDFLLGNTELNPYHEEGSSAAAEDDEKIPVSLLNRVIKDLRLEPLLDLPVAFLSNGQGRRARIARALLTRPAVLLLDEPFMGLDPPTVASLSPLLSGMAAKAQPRFILSSRPQDPLPSWTSHLIYLRTDCQVGAMGPRDVVLEGLRSYVHSVRSGKKAEDEKMPVHALGEMGRILTPGGIEGKGFDEETHSTFASANIPKSTPKQQEVSQGETIVEMNGCVVKYGDRIALGNWSQKVEDGSTVPGLIWTVRRGERWGVFGPNGSGKTTIVSLLCSDHPQTYSLPIRLFGRSRLPEPDRPGRPLTFWDIQSRVGHSSPEVHQHMPRGLTVRQIVQSAWADTFRAKPQLTPEAPGKVDACLRWFASELQPSNAATTTSETDDLAWADNYFFGELSFSAQRVLLFIRAVVKNPDIVVLDEAFSGMDESVRDKCELFLSHGETATYGTDNKIVESEVAKLGKVQVQGLTDQQALICIAHVKEEVPDCVREWVCLPEANTTSAARFGRLDGPLRTDRRRWDEIWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQL0</accession>
    <name>A0ABR3ZQL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="436"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="548"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="65796" checksum="1F2C1E9F2F809D4D" modified="2025-10-08" version="1">MATQDNHGSDGLNGLNVDTAVDADADPGLALREAFRTIRWEYRHPAGKEAYEFLRTQLPALMSEKYTHYHKMVDYGNLALMHEVIEADDVPAMRDLIRMEPDLIKSDWDGEMLCPPMVLAARLGRHAILDVMMKHRATLPPKMRVIIPEYRNDDHYLRWGSPLTTACAWGRLDTVRFLLQGMPDTDINEVALDGLTPLLAAVWVQIGPSEEKARVELIRFLLERGADIHAVRQEYDYISPDKTSGKGFDENGNECPIGWRTRPGGIGNALALALRSGRTAPGVVAVLVEAGVRVYEGHLDRVSIIDILDEVSRFRRAKVYISPIAVGAKSHNVDGVKALLALFPDDHTRLLTTMDVVLLPQVPQPPTPLRDPDDDVPDNEVAVLLPLHAAAMGTVRLEEPTLDSITDECKTAVDMVRLLTADKAICAATINARYRGHYTPLHLATGFHQMPLMLALIERGADIEALPRHNGPGLILSMFSSVSRNSHCSHVRYEALPWFAAEMDASFDVMGMLKQLLARYRPTGKDAQLDAQNAATRLALVNEADARNGNTALHFTMAYRMHRSTAALLAFGARANAVNHAGQVPSAPPPGEWPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQU4</accession>
    <name>A0ABR3ZQU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000964</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="78"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="630" mass="67791" checksum="0A68F0B727A66899" modified="2025-10-08" version="1">MVGVPGKFKGCETCRLRRVKCDNTRPYCKKCHDTGRECAGYERETVFIIGTPQDGGRCSSHPPRVIKSKKPATATVNTPSSIGSRSNSSSNFVGSSSASVSSSSGKSWTSPKSRSNSRSTSVSRTTSNSPAGALSPSSSVSISIHEQQQQRHMTMSASASAAPAPSGIMSTVKFDTAAIPIVPAMMAQRPPRPPPNAGTLKGFGVPDLVPVPPLRSAWHDSIAVASGGIVYQVQVAALSTQLQSIVRQKGSNGADGSFALLPFPVYTPTGVRPPSRDSEFHLSSQCLLPPWKDPAVQHSSIRQTGPARFATFPAHHFFARVYRPNAIWSALIYRKSTFLSDPEWTSMPWEAHPKSGLDRLLDIAALLPVMFSRSDNVTPHEPTMGRRMMAQDVLANCLYVERVLEQWHAGVQDLGMRGGPSVSGASTMSSAPASLDGSVGGGFRSGGARARASSHGGSGNWYWIADPEHTSVTAQIPFADTFAFRDTVTALMFIYYWAILVLLYPCVESLYGSIFQPVLDAFPSPYPNLPASLQIPGGDPSIYYGPKEVRELAGNVCRGLDFALATTVQPDLLAAPLFVVESFYRQINAASGDGALELLWCEAFRNRLAAKGQYLAEVVQSRRWVDAGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQV3</accession>
    <name>A0ABR3ZQV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translational activator of GCN4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GCN1</name>
        <name evidence="5" type="ORF">Sste5346_000755</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022716">
        <property type="entry name" value="Gcn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056809">
        <property type="entry name" value="HEAT_GCN1_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12074">
        <property type="entry name" value="Gcn1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25801">
        <property type="entry name" value="HEAT_GCN1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24916">
        <property type="entry name" value="HEAT_GCN1_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="4">
        <location>
            <begin position="1350"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1527"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="4">
        <location>
            <begin position="1670"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1801"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1990"/>
            <end position="2027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2685" mass="291665" checksum="9E6605C25F2A8F6D" modified="2025-10-08" version="1">MTEPTPTNGPSAAAIDPVSTRVALATSSTSLRIAQLRTIDDKIINGNLEPIAIAKFLPILFWTHASYEDRPSRRAVQKCLISICDKKNDKLLAPLVAAIRTEASKLNTSTGSTFTLVEWCSILMQQLAGTELWDKFAGDIIIAQASAVEKCTRPPARQSLAHSALVVARRGFRKLVSLDSIREKAILESVKLLGAKGAQPTARNSVFLGVIAGVSARNAKAKPIFETTKPQYFEFYTREITSSKTQLSSNVAGGLHDFFQSFVTVQDLETLIVPAIKKGLLRAPEIVLDDLITPLVNSLPKTYDLSKILEEHLAKPLLSNVKSSKEAVRNGTLTAFRALAPRCTDLDVAARVVDETLTPLQTGKLTSPEHRTIHSQILSALPKSEATAAKVTTGIAAAATKEGNETALAAETTSLTLNVKILLKGTTEVPKPVADAYIKGLADKKAPARRLWIIAAGETLYDFHTPTEGLPANVVKFAEAIFPPLLDAYSEVVANPSAASQNNLVTGGLVVCAIAPFLFKDTSSSSLSTLSKKFSLEKQCLVLQPKPSFLLTPRIYTKLVTDDDIRWLYRALVAAFPALGDDEESDASIAWAEAYIYAATTTNGGPFLRKEASSALSDLYFRNPSRVSGSIIAGLWHWLETLAAGDREGASTLAKTQNELLLSILGAICRRPSDFVRATGAEPDKNQIEQQMCGLVVLARPVLIPTSSWIELCLRAEVDPGSLAQHQEKLLLQEIAERTQLTQTSVAIKTAAYEAAAELVFVAPEVMAPRIVELIQHDLAVDELRTIGPVDAAIFRTDPGTLFVDVLAKTTSNLPSKSSKDYDVLKWEEELRAQLAAKKGQQKKLTAEETAKVNAQLKKEAEIREKVGLLEARLLRGIGVIRSLATGPPTDATQWMGPAVKALLDAIEAGACLITGDVAPMAFITLSDRVSNRLGAMRPFIGVAALRAHDVSSLPENLLEEPLPDLITRVLYRLRSTGEQRPFDSVSLIYFLPLLLLVLNKGGFSPEAEDRDAQLVLAIEVLSFHTDTCADEAIPRSDLLSVLISSMQNYSQHYKIIKDCFADMVRCVAPNMSKEETDILSQGVIVPQASVRSTVLQSISAEVDMSDLETSEEIWLACHDDVEENVELGHEIWEESDFKVTEDLPERTLAYLKSKDGQLRRAAARALAESIVLLKSSKIFDSITSQLRESYTELAKPRVAQLDEFGMPRKMDLSDPWEARHGIAAAFKELAPNLDKSEVEPFLHFLIEQGPLGDQNGTVRQEMLDAAIRAIEVHGKPIVAKLMQTFEKTLAAPDKNSDAADRVNEAVIIMYGALARHLKPGDAKIPVVIERLLATLSTPSETVQYAIAECLPPLVQTCGDKSSKYFNQVMDTLMTSKSYASQRGAAYGLAGLVQGRGIGSLKDYRILITLKGASENKKEANQRESVLLAYELLSTILGRLFEPYVIQIVPQLLAGFGDSNPNVRDASLAAAKACFAKLSSFGVKKILPTLLDGLDDSQWRSKKGACDLLGAMAYLDPQQLAQSLPDIIPPLTAVLNDSHKEVRSAANKSLKRFGEVINNPEVRSLVDILLKALSDPTKYTDDALDSLIKIKFVHYLDAPSLALISRILQRGLGDRSNTKRKASQVIGSLAHLTDKKDLVAHLPVLVAGLKVAVVDPVPTTRATASRALGSLVEKLGEDALPDLIPGLMQTLKSDTGAGDRLGSAQALSEVLAGLGTTRLEETLPTILQNVESSKASVREGFMSLFIFLPVCFGNSFSAYLGKIIPPILAGLADDVDSIRETALRAGRLLVKNFASRAVDLLLPELERGLADNSWRIRLSSVELVGDLLFNLSGISSKQEMEEGEMEEDAVREAGATLREVLGEEKRDKILSSLYICRCDTSGAVRSAAISVWKALVSSPRTLKELVPTLTQLIIRRLGSANMEHKVIASNALGELIRKAGDNILQTLLPTLGEGLETSTDSDAKQGICLALKELIASASPESLEDHETMLISIVQSALTDSDEEVREAAAEAFDSLQQVIGKRAVDQVLPSLLHLLQNDDEADNALAALLTLLTETTRSNIILPSLIPTLIAPPISAFNAKALASLSRVASGAMNRRMPHIINSLMENIINCEEEELREDLDTSFDTVILSIDENDGLNTVMNTLLQLLRHEDHRKRAATARHMAVFFAQADVDYSRYSADLVRALLISFDDRDKDVVKSAWTALSEFTKKLRKEDMENLVASTRQTLLQVGVAGSNLPGFELPKGINAILPIFLQGLMNGTAEQRTTAALAISDIVDRTSEASLKPFVTQITGPLIRVVTERSTDVKCAILLTLNNLLEKMPTALKPFLPQLQRTFTKALADPSSELLRSRAAKALGTLIKYTPRVDPLIAELVTGSKTTDTGVKNAMLKALFEVISKAGGNMGEPSRTAVLGLIDMDQDVTDANMIITNAKLLGALVKNVQQEAATNLLKNRVVPPHPTHASALALNAVLVESPAVLLESTVAEDLPALLCQGMTHKDLFIADNFILATGKYLLSPQAKTFEDTKEIFETLAKNIPPGGPADTRRLTLVLVRTLARVHLDMVRPHLPLLAPPVFASVRDLVIPVKLSAEAAFMALFDVIDEESKVFDKYLSSPAAVDLPPQTKRVMGDYFKRVTMRLAAQARERRDAEGGAGGLGLFDDEVEDEREIWSVGKVDVGADVFGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR85</accession>
    <name>A0ABR3ZR85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Transketolase</fullName>
            <ecNumber evidence="4 10">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TKL1</name>
        <name evidence="12" type="ORF">Sste5346_000488</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="356"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="685" mass="74507" checksum="BF98648916FA453E" modified="2025-10-08" version="1">MGFTEVDQQAVNTIRILAADATAHANSGHPGAPMGMAPVAQVLWNNIMRFNPKNPHWVNRDRFVLSNGHGCMLQYALLHLYGFGLTIDDLKAFRQVDSITPGHPEAHDTPGIEVTTGPLGQGICNAVGLAIAQAHTAATFNRDGFDLINNYTYCFLGDGCLMEGVSGEASSLAGHLQLGNLIAVYDDNHISIDGDTNCAFTEDVVKRYESYGWHVIVVADGDHNLEGIHAAIKEAQSVKDKPTLIKLRTIIGFGSLQQGTHGVHGSPLKADDIKQLKEKFGFNPEESFAVPQAVYDLTAKKIAEGAAAENEWNSLFAKYAEKFPAEHADLARRLKGDLPEGWEKNLPVYTPTDAAVASRKLSEIVLGKIEEAIPELIGGSADLTGSNLTRWKGAVDFQPPSTGLGDYSGRYLRYGVREHGMGAIMNGLAAYGTLIPYGGTFLNFVSYAAGAVRLSALSRVRVIWVATHDSIGLGEDGPTHQPIETLAHFRALPNCMVWRPADGNETSAAYYVALTSKHTPSILALSRQNLPQLENSTIEHAIKGGYVVHEDKDAAVTLVSTGSEVGICVDAVKYLADNHNVKARVVSLPCFEVFDAQSKEYRLSVLPDGIPSLSVEVMSTMGWERYTHEQFGLNRFGASGPYKDVYKKFEFTPEGISKRAVATVDFWKDVPNIRSPINRAFQQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSN1</accession>
    <name>A0ABR3ZSN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Toxin biosynthesis ketoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27113" checksum="0F4FCFCE7B047A68" modified="2025-10-08" version="1">MAQTTYLITGANKGIGRAMVQQLLQRANTTAIACVRQPDDPTSVSLKEFEVAESSRLLVVKLNEPADFAALQKTLAGQSVSRINTVIANAGHSTGLDKSLLETTADDVIYDCTVNAAGPLRLFQATWPLLKVSAADSTVTSRFVLISSTMGSIGVQDEESMPVGTSYGMSKAAANWFAKKASIDFKDKGLVVGILHPGWVKTYMGQALADALGMKEPPVTTEESAQKCLSQIDNWTPEKNGKFLTNSGQELPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSS9</accession>
    <name>A0ABR3ZSS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="2">
        <location>
            <begin position="96"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="159" mass="17782" checksum="9A85B84E1A09B722" modified="2025-10-08" version="1">MPPKHQRKTSGGGPGPQKDEQDPIFFHKEWKDFGFMYNYAPARFSRPDPAVVCASWLLASPPTTSLDADTSDNVPIIEFQGDWLGRDARLEILTDHGRKLLATGDRLLVEAAGRDSFWGIGYGIKQGPIRYQKNWGQNQLGKSLVATRERLRKLLGDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTJ9</accession>
    <name>A0ABR3ZTJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1903696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="103" mass="11032" checksum="785B3219E5601C23" modified="2025-10-08" version="1" fragment="single">GKITEDGNYVVGWWTSRFTRVGLPESADHAPDAETPAIVQRAPVAVAASTSTIYETTFTVTTPEAQTVCNPDDAETVIYEGEEATETQVETIALNTLATVWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTS4</accession>
    <name>A0ABR3ZTS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Flavin carrier protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FLC3_1</name>
        <name evidence="11" type="ORF">Sste5346_000417</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF2">
        <property type="entry name" value="FLAVIN CARRIER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893499" evidence="9">
        <location>
            <begin position="24"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="585"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="25"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="664"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="688"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="749"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="769"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="819" mass="88518" checksum="0CB0F0909DE9D561" modified="2025-10-08" version="1">MWSSARSLLFAAVGALSFTAASAEELLKSNSLNTCQANSGFTASLFDVVFTPHNSSANVDLVAVSSIEGNVLFDVSIIAYGLQITRITVDPCDAGLAGLCPMTAGKLSMNFNLAVGSDASDIIPGIAYSFPDLDATVKVYFNMTSGDQAGQSVACVEADISNGKTVNLLGVKWATAIVAGLALASSAVVSGLGHSNAASHVAANALSLFSYFQGQAMLGLTGVKLPPAAASWTQDFQWSMGIIRVGFMQTIFTWYQRATGGTPSQLFNSLTAVSVQVEKRSLSLADAASQYLPHSLSFMPRHIAMTPRHIVRQVTTGIHAVTNSIAKRSTLEVNSSGSYVVYGIQRVAYVAGIESTNLVLTGLTFFIIFVVIVILGVAAFKGFCELAAKRHWIKSDTFLEFRNGWFTVLKGILFRVTLIGFPQMCILCLWEFTQVDSPAIVVLAIFFFFGMLITLGWAASKVIRIARRSVAMHRNPAYILFSDPQALNKWGFLYVQFRASAYYYIVPMLVYTLVKGMFVAFAQSSGVVQSIAFILLEAFALIAASVLRPWMDKKTNAYNIAICVFNFINAIFLLIFTDVFGLPGLVIGIVGVVLWIMNAVFSLVLLIMLIVTTTLVFFRKNPDTRYQFMADDRASFMKSQTQLNTTTELDALAVTARGDKAGYKSNLDLDDDNESISSDSLRRRTDPNLAAANNIATSNNNNNLYRDPPRSPVDPSMPLFPADNRSHASSQNSGGVPQAYGGYSSVPGNARSPSPYNNSNSNLSAGGYRSQNTASPAGDFRQQNNASPAGFRQQNNASPAGFRQQNNASPWQRGAGYDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTU7</accession>
    <name>A0ABR3ZTU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000765</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382058" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="220" mass="21585" checksum="2EEACD3953039AC0" modified="2025-10-08" version="1">MKFSVASVFAVLAATVSATPAFTNSNFDVVPGSTFTLTWGNATGPVTIVLATGTAEDLTKVQTIDSNDSSGSFTWTVPTTLVSGNYAFEISDSTGVNYSKLFALTGTGSASASASTASSTAASSSSSSSAATSSSAASSSAAVSSSSSSSSTSSSSSSKTTHLTTTAGSNTTTTATKTSTTGTKATTSATTVPANTNNGPQAKSPLAFVLVTVAALLYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTX8</accession>
    <name>A0ABR3ZTX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Catalase</fullName>
            <ecNumber evidence="10">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CAT1_1</name>
        <name evidence="13" type="ORF">Sste5346_000124</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08157">
        <property type="entry name" value="catalase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="12">
        <location>
            <begin position="32"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1903497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="511" mass="57603" checksum="5113ECA8D38B715F" modified="2025-10-08" version="1">MVHPAVATDGERGAAYMHVESTYHYDEKPTYTTTSGYPIDDPKKYQRVGNGPLLLQDFHLIDLLANFDRERIPERVVHAKGAGAYGEFELTHDISDLTTIDMLTGPIGKKTPLLTRFSTVGGEKGSADTARDPRGFATKFYTQEGNWDWVFNNTPVFFLRDPTNFPTFIHTQKRNPQTNLKDATMFWDYLSTHQESVHQVMTLFSDRGTPASFRKMHGYSGHTYKFTKPDGSFVYVQIHLKSDQGVATFTNEEAGEKNGSNPDWLTQDLFEAIDRGDNPSWTTYLQVMTPEQAEKFRYNVFDLTKVWPQGEFPLRPFGRMTLNRNAQNYFAEIEQAAFAPSNLVPGAEPSADPVLQSRLFSYADTHRHRLGGNFHQIPVNTPIRSYNPFVRDGQMNVNGNLGANPNYQSSYRPLTYKPNGLGTASHEKWTGEATWAVFGDVTDLDFEQPAGLWKVLGKQPGQQDNFVHNVAGHLSGAKKDTRERTYGMFSRVDAGLGKRIKEATEKEVAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUG3</accession>
    <name>A0ABR3ZUG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ndufs1 NADH-ubiquinone oxidoreductase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NdufS1</name>
        <name evidence="14" type="ORF">Sste5346_000261</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="32"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="13">
        <location>
            <begin position="110"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="249"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1903632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="742" mass="80412" checksum="4E32A70B3FF09EE2" modified="2025-10-08" version="1">MLRQALSRTALRTGRHSVRASRAFSATAQRPAEVELTIDGKKVSIEAGSALIQACEKAGATVPRYCYHEKLMIAGNCRMCLVEVERAPKPVASCAWPVQPGMVVKTNSPLVHKAREGVMEFLLANHPLDCPVCDQGGECDLQDQSMRYGADRGRFHEIGGKRAVEDKNIGPLIKTSMNRCIHCTRCVRFANDVAGMPELGSTGRGNDLQIGTYLEKNLDSELSANVIDLCPVGALTSKPYAFKARPWELKHTESIDVFDALGSNIRVDSRGLEVMRVVPRLNDNVNEEWINDKSRFAVDGLKTQRLTIPLVRREGRFEPASWEQALSEVAHGYAKVAPKGNEFKAVAGALVDVESLVAMKDLANRLGSDNLALDTPTGSVPVAHGVDVRSNYVFNSRIAGIEEADAILIVGSNPRHEAAVLNARIRKQWLVSDLEVAVVGESFESTFEFEHLGTDYAALKKALAGPWGKKLQAAKRPMIIVGSGVTEHADAKAFYELVGGFVEKNAATFQTEEWNGYNVLQREASRAGAYEVGFVPPSAAVAETKPKFVWLLGADEISEADIPKDAFVVYQGHHGDKGAQLADVVLPGAAYTEKSGTYVNTEGRVQMTRAATSLPGAARTDWKILRAASEFLDVPLAYDDLAQVRDRMVEISPALAAYDVVEPVALKQLAKVQLVDQNKGSKSTGAPLTKVIENFYFTDAISRSSPTMARCSAAKASGNPKTNFMAPGTGEDKPLGQVAYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHA7</accession>
    <name>A0ABR3YHA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000133">
        <property type="protein sequence ID" value="KAL1887247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="33"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="439" mass="48442" checksum="2BF44374C718F0A2" modified="2025-10-08" version="1">MTNNNQHTSGTVLQRGTKEYEKALGNYFNSEPVGRFPVEIHSVQSTADVAAALKRARELGVPVGVKSGGHLPSKPSLINGGILIELDKLNRAVDYDAVSGVVSFGPAVRVEEAWKATDAVGRFFPFGHAPDVALGGFCLAGGQGFSMRGWGATITNWIIQLEVVVPSGDVVIASRTQNQDVFWAARGSGQAFFGVVTRLWSRTIPKKTLYARSFVFTLFNTKSTEESIPSSSSLLMSIHLTAYANTLSEAENLLAVWDDVPEAIKSLSVDAKPTAEISWKDFFQLQHAMNPRAPDQNWGIHSVLNDPKVPRKKLIKAIKQALCDLPSRSSYGVIYMADTVDVDETDAVFSLPQKYYISTFSGWKNPELRDPIRAVMRQSYAKANTVACGMYIADFDPSPESTHSRTVPVWTDTARERFMRIREKWDPHGVFPGYKAFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHZ4</accession>
    <name>A0ABR3YHZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="3"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="553" mass="60634" checksum="70BC970725B9DE84" modified="2025-10-08" version="1">MSTIHVTGGLVQGVASPHDPSITLYKGVPYAAPPLGQNRWREPQPVVPWEGVKVCDVTGPVCPQVAPDPRYVNILKGWPQSEDCLYLNVFLPPNTSAESNEKKPVLVWIHGGGFREGGAADPNFDGTGLAQKGVIVVVPSFRLGMFGFFAHPDLTAESPNHTSGNYGIYDTLEALKWVHNNIAQFGGDPCRVTVSGQSGGSAKTHILLLSPLTKGLLHGAIIQSGARSPKEPALAVGAPSWRSLKQAEDEGVAVLKELGLPDIAALRAYQDIPKIAEMSLKRDTTRWGPPPFFRAVLDGYVFPKKYSETFDQGPPNDVPVITGQNRDEGGVYNEPRFTYDDFVASARGRLGPDQTHSKGSEELVEKFLEVYKPADKEEGKGPLDAWNQSARDNTRLNLSLWAQEYHKHTKSPVYGYYFTHAPPPWHGWTQPEPLASPKTPGYTNGKGPLTGAYHSAEFAYTFNSLTTNNIRPWADEDRVLGDKVSTLWANFVKTGNPNGKRPEDRPEGVPEWPSLIDKPDTLLELGGNFEYVQTASPEARAFWESYINAQPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIG8</accession>
    <name>A0ABR3YIG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dihydropyrimidinase</fullName>
            <ecNumber evidence="6">3.5.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009998</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16121"/>
            <dbReference type="ChEBI" id="CHEBI:11892"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15901"/>
            <dbReference type="EC" id="3.5.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050378">
        <property type="entry name" value="Metallo-dep_Hydrolases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647:SF1">
        <property type="entry name" value="COLLAPSIN RESPONSE MEDIATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647">
        <property type="entry name" value="HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="7">
        <location>
            <begin position="53"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="57924" checksum="29C314F4B5B13388" modified="2025-10-08" version="1">MLDLIIRNGRIVTASEILPAGLEIGVKDGKIAVIGIGLDAGPDTEVVDAEGAYITPGGVDSHAHIEQDNSPTGDTWETGSRSAIAGGNTTVLAFASQRRDETSIKPCVERYHAKAGSNSYCDYGFHVIVTNATYAVLEEDLPSLAADGITSVKLYMTYLPLRLGDGDLFSIMMAARQLGVTTMVHAENHDMVDQIAKRLAARGHTQTQFHAVARPQIAETEATYRAISLAEVTDAPILLVHMSAPAALEHVRAAQAHLLPIHAETCPHYLYLTSQKLHSHSYDEIDGAQHICAPPLRHDKKDLEQLWAELANGTYTVVSSDHAPSLYDHPNGKKRGFVVAEDGTKTVDFRVVPNGVPGIETRLPLLFNRTYDPEVGPPASEDAPVHISLPRFVALTSTNPAQLYGLAHKKGSLQPGLDADIVIWYPEATKSGSSSTVLTPSSSTESVASPSPFLITNSMLHHCIDYTPFEGMSVRNWPRYVFLRGRRVWDRDNGGVLGQPGDGEYLPRTKSRILTGQLGRTVTGMAYGERKAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YII7</accession>
    <name>A0ABR3YII7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="490" mass="52581" checksum="69839D8298F6B799" modified="2025-10-08" version="1">MTTRNALDPRDFAKLYLNGEYVAAKSTETYSLNNPKNNTLAVDKIPIAGAEDIDAAVSYAEAAFHGPWSQFTAIQRTECFIKLASLLDEELMPILALDSLTSGIPLSLAPTREKTYIRNCVIYYAGWTDKQKGDYFPADDGFVKLVRHEPLGVCAAVNPYNSPVACLFLKAMPALATGNVMIVKPSEKTPLGTVAIASLFAKAGFPPGVLQVVTGPGSTGALLAEHMRIRKISFTGSIATGKRIQTAAANSNLKRVTLELGGKSPAVIFDDANLENAVNWTVNGILARSGQLCVAASRVYVQRGIASAFIEAYTKRMAAAVDDIGDPQDLNVKYGPIVDKGQLERIKGMVDRAKADAELVVGGGQLPGTIGNYMQPTVFLNPKNDSEIYRNEVFGPVSIIKTFDTEEEVTKAANDTEFGLMAGVFTKDITRAMRMSSAIDSGVVGINCVSLQSLQAPFGGKKQSGVGREFGEYALRLFTEPKTVLINMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIM0</accession>
    <name>A0ABR3YIM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF5">
        <property type="entry name" value="DUAL-FUNCTIONAL MONOOXYGENASE_METHYLTRANSFERASE PSOF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="280" mass="30307" checksum="DBFAF6BF2D6EC77F" modified="2025-10-08" version="1">MTKKKKKFKSKSKSKKGKSTVEDDEDTAVEGEETPSQQQDKQQHGEHQNAVTLVPKYSFMAKRPPSGHSYYETYNRRNVMPVDISGEGGGVDGYDKGVLWGATAKSSRSRSSWLPPASMPAQALWPLLTSVAPKASPSKTPGAPLGKDSLQTFSGVLTPGFPNLFMVCGPHVPFGNMPIVIEDAVQWIGQCLGYMTKEGANKVDAKKEVAAAYMAELHGICDATLFGAAAKVQGAWFADGNIPGKAGQALFYFGGLTGWRRWLDGETKDNAWKSLAFEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT7</accession>
    <name>A0ABR3YIT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="8"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="406" mass="43432" checksum="19FB3581E69901AE" modified="2025-10-08" version="1">MTTSQPRIAIIGAGPAGLALGVLLQKKNIDFTIFERRSKPTAEELAAPSGMLDLHEESGQAAIEACGLTDEFRKLTADCSESMAIIDRDGNILHTDDGGEQNRPEIARHALISLLLGQVQPAHIRWNQKIVAATEQDDGTVSLEIDGSVAETFDFVIGADGAWSRIRPLLTSTKPEYAGLQYVTATVRDISTRFPDLASLVGTGTCFLLGSSKTAVIGHRGVRDTQCLYVTVGTDNSGDIFAGLDSSQIKEALLTRNDMFGPWGDSTKALISAGLDDTIISESDGLPTAKPMYQLPIGHSWTSRPSATLIGDAAHLMLPYAGEGVNLALWDALNLSCVITDAVFVSTSGTSFQEALREPLVAFEANMATRAGERAEETEQNRSIMFAENGAQQMADVMKSYGPPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJP7</accession>
    <name>A0ABR3YJP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="53609" checksum="1E99C0F25B734180" modified="2025-10-08" version="1">MHPSTTSTTDSQNGSTSSSTAEARRLRKRELDRHAQRCARQRTKDRIAFLETRLEESYRAEPGRRRVATLLDELAAVKQQRDELMAIVSSIQKTLVGVSTTTQHTQNTQHTSPPATTTPPLATLTPSPPAPEPLVVDEVEPIVPLPEVPCHCINDTPSSASTSTASRNIWRSVNCTLTKSQQHAPSPKIADTILDEDVPVRAVLEGWQAVERAGLLSAAWKKLRAVDELCFATCDQVVRLAVMATMYIFLRWDTDPTPQNLQAMPKWYLQRPSQKMAHSGAIDYFVWPGVRERFVFSQHRYCSNLFWNTFSANLRILWAHGFDSCYQLDLMTGRYCIAPAFRNQIRDLRCWTMLRGFFDHFPDLACDIPTYDDIPQSLPLALSFSDILEDHYEEEQDVQDVQDVQDVQDVQDVQVALQDALQDVGQEPRMEALPYGMTPAMQLGHLRRSDTADDVDFWQLAGLVSGDGQGFAQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKH3</accession>
    <name>A0ABR3YKH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase-like domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="869" mass="96085" checksum="5C67C6E91BF0F3A2" modified="2025-10-08" version="1">MSDAPDYRALYEEAERRRQEAEQRRQEAEQRQQEAELEAQRARQTIQETSTFNWLLQKELAELRKSTARQSLQAYLAQVSKLHIHLARLIPGPQQPRPGPKASSSSPTTSGRTDIARKYYPLRLRRWEDFDAVQRRIFSRIYTTLQDRQVLPSRQSVQHDEASLLEQLPLGVLNLSGSMTEARTTEVVNLSLLLPASRIINEYLADTDTEQKMFFDTHTYGAAPESAPGSSAGTDSEDNARRLTSNSERRVKKVMPDCLLLTMPTVVPGQAADDSETAARRAAIGEHKPAHAVRGTHVVEIVGHLPESYMLMLARETLARRSTPVAPASDELAGGLAGGEGMASTSASTRPVEGGDSSTRKITKQTYFAYALTQTYHYMIITGVPYGYLCTGETITFLYIRGDDPGTLFYHTSSFPLVSLEDVRSAPGPVTTTPVDDDTTLPDVETLSKMAIAELCSFCLLALDTDVRSADWTAKALAHLAQFPELPASLAAARSPGPSSLGTRRRDSDDDGDNERNRPPPPPPDGSYGSARGHGPSPLRHEVPRQDAHSSIEGHQRSVFTGIASSTLSYCTQACLLGLVHGGELDTKCPNYRLHLQSGSWPGHRHSITQDEFTRRVREQLFNTPSVNCKCYLGNRGCIGFFFKITLTGFGYTFVGKAVEEHYRRRLVHETEIYSHLLPLQGVAVPVHLGLVDLIVPYPERETFTLLKTMMLLSYAGRHIPSDDDEDDGADLPSDLKHEIHRTLQELGDLGLWDKDSNPDNIMWCDDVQRVMRIDFDRAVIVPSRDKSRVSDAPATPGTGDTAPMVNTALGDGKDQKDRENGEDEEHGEHGEDGVVPSPRPSKRPRYEGELAGSHAESQPRTATSMPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKL4</accession>
    <name>A0ABR3YKL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mannosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ALG9</name>
        <name evidence="11" type="ORF">Sste5346_009501</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050103">
        <property type="term" value="F:dextrin dextranase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF2">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE ALG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="619" mass="68519" checksum="D069C53D4941DAFD" modified="2025-10-08" version="1">MVDTTESPAKKEFVHPAARHAKKKPTGNTFEPIKAFYLFLAAGIFSAVYAPIQDCDETYNYWEPAHYLVHGYGRQTWEYSPDYSIRSWFYIGLHAAVAGLRRILPQASKVGEFYFVRYILAVVCALCQTILFQVISGTVNPRIGFFFIIALFTSPGNFHASTAFLPSSFAMYAVMLGAAAFMNWRGGLKTLRGMFWFAVAGVIGWPFAAALCAPFLLEEGVLALSGGGSALFDGFIRVARGVVAALVLVAVDTAVNTFFYRKVAVVAWNIVKYNIFSAAENGGGPNLYGTEPWTFYFKNLALNFNIWFVLALAALPLFLLQKIAGTSKKGLVSGMRAVVFLTPFYMWLAIFTLQPHKEERFMYPAYPFLALNAAFALHILLEAIGHSTPGTLAGLIPGKVKLLAVLGVFTSCLAVSGLRIYGVISGYGAPLSVYKPLGGNVVHHDVAAGIADGSIVGNTGDFVCLGKDWYRFPNSFFLPRDMHVKFVRSEFRGLLPGEFSEARTGFGLWSGAWLPTSGMNDRNEEDMSTYADISTCAFMVDTQYPENARLGKALPPHEPDYVADTANWEIVKCEPFLDAGNTEFLARALWIPDLDVLPEKYQRKWARHCLLKRREQKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKV2</accession>
    <name>A0ABR3YKV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF4">
        <property type="entry name" value="SH3 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G13610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="372" mass="37800" checksum="06C6901B9F73724D" modified="2025-10-08" version="1">MSDYFDDYFFTSNVSDHTCPGFGSNVCKPPNACARDPNTGRRFCCDVKDVCWTITETCANDGSTIDCGTGSTKWCCVNGREKCTAAKNQINICWSTEHDILNNITNKMLNNTYSSLSSAHPSATTWSFDPEALIAQTAPPTSSATSSGADTSATSSAPSPSGSSDNNTGDSSTSVSGGAIAGIVVGSIAGVALIAAGLFFLWRRARNQNSGQAAAVGGYQAPGSGPPPGGIPEGSVAGAVAGANGLDDKARYAGAPNFGGHDYTNNNSYYTGSPSPHPPPSSIPASELHGDNIVPQELPANTAFGAIPSELSATSPSVATHYGAVSHTVDSPASVPAVPASGSANVSPEQAYQRPYQAGGAVAAPSPQEGHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLH5</accession>
    <name>A0ABR3YLH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045988421" evidence="1">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="179" mass="18455" checksum="8E59BDAB391998B5" modified="2025-10-08" version="1">MLFKSAFLVAAATSALAAPSVEKRAVCKTNKPIDTFADFANKTNSLGAVNGDDKTMGTIAASGTTLSLTTKAGSYFYENLPCEDLAAATSGFTGIAFKLSGPAQSSFLLEIQTKTNCNATTHASVFHNVTVPATAGQVTVPLSEFTGANLAVATSLTFSTFNKTGAYTLSDLELICGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLM2</accession>
    <name>A0ABR3YLM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Xenotropic and polytropic retrovirus receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SYG1</name>
        <name evidence="10" type="ORF">Sste5346_009005</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="580"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="621"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="800"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="845"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="9">
        <location>
            <begin position="1"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="8">
        <location>
            <begin position="734"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="939"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1098"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="949"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1003"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1141"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1158"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1180"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1213"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1235"/>
            <end position="1244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1244" mass="137719" checksum="FE0644E1DA4103DB" modified="2025-10-08" version="1">MKFAKELDQELVPEWRVKYLNYKAGKKYVKAVSRAISRANTTPILHRRSGDLPTRQTPRLFAPGSPFSAKRQSSNNNGTSPALARAKTASSRIPKHGKNDIDDGDEGERRSLTSTPIDRPQYGSIMNTSRIRSPSVATDGSRTFELPAPAMRVPSNTNEPAQPASVAKSGTTGASVPPGARPKRRSATMAVIPSGGGSSGGAGDGNSGLASTPSRGAAFPSPYELTPRQRLRRMFSVTSPNQWPAGGNGGGSTVGDNKDDISMRAFDEVRERELEFFRFLDGELDKVETFYKFKEQQAGERLATLRDQLHEMRNRRIDEIQHARRRGIEEPEISPNASGDDEGSRVRSAGNGSGGNSGPQSDGEDGKAWDVYQEWIAPVRAKIFKPGPNSKALQKMPQTPRMLGAGSGVPGVDGHRDYVRRPGDHDIPYRTAKRKLKLALQEFYRGLELLKSYAMLNRTAFRKLNKKYDKAVNARPPYRYMNEKVNRSWFVNSTVVDDLIVAVEDLYARYFERGNHKIAVGKLRALTKRAGDESGSAFRNGLMIGVGAVFAIQGTVDGATKLFAGDPLLHEQTSYLMQLYGGYFLMLYLFTLFCINCRIWTINKVNYPFIFEFDPRSHLDWRQLSQFPSFFFLVFGLFIWLNFSDAANPRLFLYYPVILIGFTFVLLFFPAPVLWHRSRKWFLYSHWRLFFAGLYPVEFRDFFLGDMYCSMVYSMSNIELFFCLYVNSWNNPTQCNSSHSRLLGFFSTLPPIWRLLQCIRRYRDTRNIFPHLVNGGKYTMTIASYVMLSLYRIQESHSNLALFITFSTINSIYTSIWDLFMDFSLMQVDSRHFMLRDILALKRRWVYYVIMVLDPILRFSWIFYAIFTHDTQHNSICSFLVSFAEATRRGMWALIRVENEHCANVAQYKASRDVPLPYHLHELDSSLDQASHPLLQGTEGEAEDDDAQGTLAGTSRRTGTAATGVEGTPNMTGGAGGTPSVKGTPGRATLSGSSIRSSKPKQQEQPSPQQPAPGTAGTAASTTTWPNIPEEHGSINAAAATEEGTAGVATTGTSTGVAVYSGSPSIPAASGNDFGTLRRRFTSTLGKSIGVIMAEAHKQDFEKKRKPGAMDGASPMGRPGPMDDLPSSDEDDDDDHHSGVGDDDDDGDLDDLADYDEGVYHDHDERGERDGQGHDDSGVADSQAPTQAASPQTQAQPQADDRTLDGRNSQGRNRGHSHQSHAGHSRGGRSGGGSSSVKRGSPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLP7</accession>
    <name>A0ABR3YLP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439130" description="Cell wall protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="35060" checksum="C083AF63E26BCF07" modified="2025-10-08" version="1">MKPGSLIISLAFMAFSSALAQNSTASTDVGKHNGSGGEHNGGGHQNHHEHERGKEKHHHHKLKGVNAGSTLERCTTLQRFNNILDTAANATQLQAKFKGNTTRIAHIQAEAAQLQNATSPQGALLVSLRSNATFLGICDAIFATESNDVQCKRLLLLESEAAIAANATALTKLAHGNNTKAQQIQAEVIKSQPELATLQNNQTLQQFCAMFQTRAQCRVIKELYGDVSLARNATKLNQTLEGNTTRIAEFQSLVAKATTQLDKLLNNATLVSVCKTEMPYIIDLANELPNATVTSADSVSQSDASRSAAGSMVSLVVFFMLSFYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX2</accession>
    <name>A0ABR3YLX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="131" mass="14017" checksum="F3B975A369F0E4B7" modified="2025-10-08" version="1">MASQDPSTTIPLVHAADGVGYRLIELPAELVDDHSRWSLSSSSSDGLARLRAAGKTYALRQKNTSNALVLLQATALPTDGELKPTVSAIATVHETVELVEEKEDSATASQQAKPVAAPARGKWHEKFGRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMW2</accession>
    <name>A0ABR3YMW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">A-kinase anchor protein 7-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019510">
        <property type="entry name" value="AKAP7-like_phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009210">
        <property type="entry name" value="ASCC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13360">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13360:SF1">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10469">
        <property type="entry name" value="AKAP7_NLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A-kinase anchor protein 7-like phosphoesterase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="278" mass="28966" checksum="231FA7121B00A974" modified="2025-10-08" version="1">MPPPKPPPRPQLTHFLCIPLATIAGRPQLADSLATFHADVAATSVAMTSGGSGGPSSANNRNTTVRRGPLPPTALRPVGTLHLTLGVLSLDGDRLQEAVSRLQSLSRDDKVVPAAGAAEEKPISMALRGLHAMQPPARATVLYASPVDEKTGSLAAAGGPLLELCERVRSVFADLMVPDERPLLLHATIVNTVYAKERRGGSGRGGRGGNRGGGGGGGGAKLTFDARELIERYDDFVWMEKVPVQKVALCRMGAQTTAVDDDGAVADAAYPVEAEVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN79</accession>
    <name>A0ABR3YN79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome transmission fidelity protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ctf18</name>
        <name evidence="3" type="ORF">Sste5346_008975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF3">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="342"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1095" mass="118589" checksum="5180A52DDFD7EA20" modified="2025-10-08" version="1">MDTDVVSQRVAAPLPSVETVQTVPATAAPQPVKRTLGGFVDSDDEDEDDDIPSATAPITTLTQTTSTQPAATEANTNSTAPSTQPQPTTHSTEPLSTQPTTNISQNDDTNMHDAQVPSQFELDDLMAQSAPPNEEPESQEPGEHEENEEDRYDLLFSAAPAADPIPKVTPTTTSTVFVQTCSGRSIPVRQRSTPRAPVPYEAMVAQRSKTKEGRAQRNYYGIAIHELVDGARKEMATQKEAEKKKATEAEAQPVPEVIPEVVETKPVKGKGPGRRPKKTMLWTEKYRARSFMDLVGDDLTNRLVLRWLKRWDPLVFPGAKKRVPLVKAPNSDNNNEETEKPHRKILILTGPPGLGKTTLAHVCARQAGYEVLEINASDDRSRDVVNGRIRTSLGTESVKAVEQTTIGASSAGDTKKGKVARPVCVIVDEVDGVVGGTGSGGEGGFVKALIDLVLLDQKNSGGGAAAQASSAATSRRRKRGDDFRQMRPLVLICNDIYHPALRPLRLSGLAEIVHVGKPTVETVVTRLKSIFEKEGIPCEKEAARKLCEAAWGMATGSEAARRGTESTAEGDLRGVMVVGEWVARRLRATASKETLASASPHLTRSWVDKHILPDLASGGGGGGIGARGLGRGGVREIVTRIFQEGAGFPKTAASTAASSSTSTASASGTSATTSYRHEQPKEQMSFAEAQQRYSMGRLREMIETSGDVDRIMTDIFGEYPHREFNDDSYLSKPDAAYEWMHFHDACARRVFGSQEWELAPYTSQPVLACHQLFATSKKHVPEDTKGGGDENRPVIPFTGPRADFLAREAEKHSRAALQTIQAQLPPSLLRAFRNAEDLASDFLPYVLRLVSPDVKPVLVNVVAAPTNNGKSSGPTAVASVRREGEKILVRRAAEVLAELGIKLQRGILEDPSNPPASVGSRPQWVYRMEPDLDMLASFETASGLVMASNAAPTRYAVRQVLDQELRKTLAARDNAARQARFQAGTALGVPLGSVDDDKENQGKKGSLKRKSAAAELEEAAVKRDFFGRIIAEVTTTTTNALQEVDGNAREGRSLAKNNASTDDEDRTQRVWVTFHEGLNNAVRKPISVDEFLRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNP1</accession>
    <name>A0ABR3YNP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF5">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046617647" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="31"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="335" mass="36308" checksum="431D6B50DB6D27E4" modified="2025-10-08" version="1">MKFLVALAVAAAPAQAALRFGCSTLSIQRLDPLVQPGAIPSSHLHQIVGGNAFNATMTGDIGAQANCTTCTFSEDFSNYWTAVMYFKAPNGTYKRVPIMQNTALPNGINGGMTIYYTQQDFSSNGNQKITAFKPGFRMTVGNPATTSLSAAEGHVGLRFVCLDEKATRFPELPTFPTRACVGGIMTVHHFPSCWDGVNLDSPDHQSHMYNTQGEAFSNAGACPASHPVRMPQVAYETLWDTTGFNHLYPTDGSNPFFMSYGDDHGYGTHADYVFGWKGDSLQRAMDSSCMFQGCENGKPLLSQSVTEMNKCAVASTVHDDIDGWVTELPGQSMQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNV6</accession>
    <name>A0ABR3YNV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="217"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="52280" checksum="1623DEA69606AB00" modified="2025-10-08" version="1">MAPQLDGFFKQVDDLSNQFIDRLAKAVAIPSVSSDAARRPDVVRMAHFLESELKTLGAEVELRPLGKQPDNPSLDLPPVVLARYGRDANKRTILVYGHYDVQPAEKTDGWNTEPFELTVGEDGRMLGRGSTDDKGPVLGWLNAIEAHQKAGVDFPVNLLMCFEGMEEYGSEGLDELIEAEAKKFFKDAEAVCISDNYWLGTEKPCLTYGLRGCNYYSIEISGPGADLHSGVFGGTAQEPMTDLTRVMATLVDTKGVIQIPGIAEQVAPITADEDSLYDNISFTMETLHESLGSKTTIFEDKKSTLMARWRYPSLSIHGVEGAFSAPGAKTVIPAKVIGKFSIRTVPNMEIDKTNELVFKYVKEQFAKLGSKNTLNVGALHTGNWWVASPKHWNFSAAAKAVERVWGVEPDFTREGGSIPVTLTFEQATGKNVLLLPMGSSTDGAHSINEKLDKRNYIEGIKLLGAYLHYVAEEPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPF5</accession>
    <name>A0ABR3YPF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008685</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="465"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="751"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="906"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="784"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="818"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="918"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="946"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="972"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1071" mass="115929" checksum="104EB68499368E20" modified="2025-10-08" version="1">MLPVSKNKGPRACSTCAKAKSRCVPGPVPNICERCHRLNKPCGLQTPAPPRKRRLDGAMEGVRATGVAQNGNGAPNGGAPGHHNGHNGHHASGNPHMANGHLNGHPASGKTQQRAGAKPTRVAELERRLEDLTSRLDSVSQQQKLHREINPPESNDPNHRTNPLDIFRLKAHWGYMYPARHIFPNDNVNMRPDESGNNGPKGAFGSRQSSFSQQHAGISPPVTVIASPTSNAQNGGSSSGPASNGGDKDDPTPPCTLIPSFVMPGQRQYFHQASAAADAANAKKHRDAAANIAVAAAAASKQQQRYYPPTSMPGEGAPTPASLPSLNSVNLTSDNIWPKNDEAEIMLSEFRKFMMPLFPFVIIPEYITSEQLRIGRPTLWKSVMMAACHLDGARQIVMGNQLLGELAAAAFLQPRRTLDMLQAVLVLIGWFHYNINSFQLINFFYLARAMCVSLGISEPLPPLVAPPRHKKAGPGAGGAGATGGDAAPGSGFNNAGSNSAQAGNNEDGTDCNPLRQTTEYPPVALEQMRTFAGTFYLVALSTTTNKRPDIMMNTAYLETCCQVLERQMEYPSDAYLLQLVRIQQLSQSISVAYSLRGDGMQMGMSLRHMMQNLRQQIEAFKAQLPKAYENDEILLYEAGLQEAGINPVLRDEPMSASDRLELLWACTYAIKDLMRNRFQDHITDQPRFLCLSSFDFMFAFLTALKLMTLQAPGWDGRRVRSELAFDDLIDRQILDLQLLAERRSQNRFRISPEEPLRLSKTDGAGASEAVPSSATATTSEHVSRSGTSSGSSSSNGSPASNEADAIGEDATPTNNSTNASGNADNNKKNNNNAANDANNSKTGNNGRPVWDPRHDPFTRLAERLIELKSMISKELDHLPGNSSGALHPLINGAGAANTMGPLPFASMMDAVPGGSSSQVDQQGHDQNQGQNPMQQQQQQPADMDTEMTSSSPNTINVAAPGIPGYAQMATDPQQQHHQYQHHQQQQQQQQQQPPHLAPPGAMAAAAPDAPFDSITINAEPILSFADATIDYMQNLDGPGFPDLFNAPGWESYMDANMGTPSFYDSWGQMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPJ9</accession>
    <name>A0ABR3YPJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5-aminolevulinate synthase, mitochondrial</fullName>
            <ecNumber evidence="5">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HEM1</name>
        <name evidence="17" type="ORF">Sste5346_008686</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="16">
        <location>
            <begin position="237"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1889828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="674" mass="71591" checksum="7D84A714E571E27C" modified="2025-10-08" version="1">MDAVLRQSKAVCPFLKKASPATLRALSTASRQSAAAPEASSALIAASPCGGALSKLQLLAGRCPVMGKAMAVQATRIGTSRVAANSSMGYRGVAASLSQAFSTSARASAPAPARTCPHAAASATASSAPRTARLHTSRSQEARAVDGHVFNEKGIPTSIPGTAKVPKAAKAAANKASTTPGFAAAPAMMQTKFDYEGFYEAELDKKHKDKSYRYFNNINRLAKDFPRAHMAEKEDRVTVWCANDYLGMGSNPQVLRTMHETLDEYGAGAGGTRNISGHNRHAVHLEETVARLHAKEAALVFSSCYVANDATLATLGSKMPGCVILSDSLNHASMIQGIRHSGTQKIVFRHNDVENLEAKLAALPLNVPKIIAFESVYSMCGSIGPIEAICDLADKYGALTFLDEVHAVGMYGPNGAGVAEHLDFDAHVQGRPSGTLMDRIDIITGTLGKAYGCVGGYIAGSSQLVDMIRSLAPGFIFTTSLPPATMAGARAAIEYQMGYGGDRRLQQLHTRAVKESLAARDIPVIPNPSHIVPILVGDAEVAKQASDMLLHDHQIYVQSINYPTVPVGQERLRITPTPGHVKEFRDRLVHAVDSIWTELGIRRTSDWARQVPGGFLGVGAPPAAENKPLWTDEQLGITQAVRELQEQKQVGSNGVTEALLAQEKQSSSTVSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPK5</accession>
    <name>A0ABR3YPK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lumenal Hsp70 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LHS1</name>
        <name evidence="6" type="ORF">Sste5346_008390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045520953" evidence="5">
        <location>
            <begin position="25"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="615"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="836"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="953"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="633"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="836"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="953"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="968"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="981"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1015" mass="108737" checksum="D6FE5206B395C0E8" modified="2025-10-08" version="1">MARRTISLRLAFAGLFLFACHVLAASAVLGVDLGTEYIKAALVKPGIPLEIVLTKDSRRKEIAAVAFKTPQGGPKAGDYPERAYGSDAMALAARFPGDVYPNLKALLGVTLDGSEGASAVIQEYAARHPSLKLEAAFKDRQTVALKSSGAFVESEDAWMVEELLAMELKSVRRNAEALAGSDTSVRAAVITVPPFYTADEKRAVELAANLAGLRVLSLISDGLSVGINYATSRQFPSVDSVKGKEAGKPEVHMVFDMGAGSTKATVLRFQSRSVKDVGKFNKTVQEVDVLGSGWDRTLGGDALNALIIDDMVAQLVDSKAAKAAGVSATTVQAHGRTIAKLSKEAERIRHVLSANTNTAASFEGLYNDIDFRYKISRADFETMAEAHSVRVNAAVQDALRMASLTVADLDSVILHGGATRTPFVQKQLEQVFGGASKLRTNVNADEAAVFGAGFRAAELSPSFRVKEIRVSEGAVYGVTMKPAADDAGVLSERQIWVPTSHTGPVASTQEFVYQLSEDNKAEASVVFYQQVPGPDGKLVESAVKTFASSNLTATFDKLVEKHACEPSTIQFKLGLRLSADTGEVEVVRAVATCEAEGLEKESIMDGVKNLFGFGKNKDQQPLEGEADEDAEADATSSSSSTSSTSSTFSSTSSSASSSSSAAAAADDKDKEPAKKERVPIAIPVKFTLEEAGVRALSDTELQSVKKRLQAFDASDRARLQREESFNQLEAFTYKVRSLLESDEFIAASTPIERSTLEEMRSETSDWLYEGGADATTEELKKKYTALKTPVDAIETRISEGEKRPELIKGLREALKQSRDFANSIRDRIVEYEDFQAAKAASSSTSTTSSAASEETPAKADFDGLEDDEPVVAAAASEKSPEDRGPVPPIYTRDDLKESEDLAASVGAWLDEKEAAQAKLGPTDDPVLTAKELQAKRDHLDKVGLDLAMKAVRNFEKTQKKGGSDSKSKSSKSKKTSKTKTKTASTSSSSSTSTSSTEAKPSKQATQDEEIKHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPP5</accession>
    <name>A0ABR3YPP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="594"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="846"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="127"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="786"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="801"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="850"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="991" mass="106054" checksum="C9D199828714F007" modified="2025-10-08" version="1">MPLGSVSPRSAATGVGNAFSGSAAGDDRAKATAKWGAACASCAAAKAKCIRTNEEPGSKCDRCERLFKDCTDQIHRPRKKRASKPSKTAQLEERLNGLVDLLRASGELPTNVANAAAAAGVSIPTGRATSSTADRPESTSTDSPTNAASVRSGSAPSGPSTNPSPPDTRDSRDVRNIHNIRDDYPDQDARDREPRDVRRETVPNTTPATIPSTYNSFAPPSCICRPEIGDTITDAVESDETLLQKYLTHMQPLAPIVVLPKSVTAAQLAVDRPFLFLAIRTVASVDNYRSMQGLMYQLINHVADYMLLRAERSLDLVQGLLTIMSWYHHHCMMHAQLGNLLHLASSLVADLNLARPARLAERTDLMVLHPNPPSPRTHEERRVLLGLWYIRSCVALCFQKTEPMRFTPYIRQCMHELEEAKEVPSDAVLVAMVRMQLLAEKMGAFNSREESADDDIPHYPRAPKAAYKIAFRSELDQMVASFSADVKKHVIIESHVCAITLRLYEPPLLDLPLLRKLSTSLTSASSPMMATALDMLYSARTALNGFFDHFFSISIHIYQYLPIPLYVHLIYGITMLSRWARLIGPTRPANANNNAANLRGPAFANKDASAGNTPVTSSTESGTGTSAANNGASSSFVSTPDLDLRDPSHRLVPGQGAAATKPGLGGLGGGPVTSIPFQFIPGMDARELQRDPSLLKAVARLREHMRQQPDLQLDIPATLATIWDKFEQSNREMRASGAAKFGDSVGRGMNVWDLTARKIAIMRFKVGRYLDGATTGAIGGANDSAGGSGGAGGTGAGGDAGTARDSNTTNVANNTTSNTAAPPDQQRQPPAFYSYLPYAQQMFIPGSGYSQQSQTSSQTETPASHQQQQQQHQQQLPIHTAHTAHTGMTFGTTVTGGTPSQAQQTPAGTSSTGGPPPMPLNGLPPDMAGYAMGGSGVPGGVGAGLGVADISFGLGNLEGWENDPLWGADLFGTGPDPAMWAENMDWVATLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ89</accession>
    <name>A0ABR3YQ89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008179</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF19">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01812)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="50"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="496" mass="54893" checksum="95C92DCD4082463B" modified="2025-10-08" version="1">MSDDEKAHGVPVADTISSIPGLPPDPDAHLSDAEREAIDRKLILRLDFILIPWLCLLYLMAFLDRTNIGNAKIAHLATDLDLSTPQFNMTLTIFFISYSVFEPLTNILLKRLRPSIFIPIIIVTWGASMLGMGFVTNYSGLLAARWFLGLCEAGLFPGINYYLSCWYKRSEFGIRAAIFFSAAAVSGSFGGLLAAAIGLLDDKRGYAGWQWIFIIEGALTMALGVVSFFMVHDFPDEARFLSPDDRVRVIRRLKLDQQSSAEHEEFRSSYLMAALKDWKMWLGMAIYMGCDMPLYAFSLFLPSIIANLGWGGSVVHSQLMSVPPYAAAAILTIAIGYVADRTRQRGLCNICTSLLGIIGFSMLIGSARPGVQYAGTFLAALGIYPCIANTITWVANNAEGVYKRGVVLGFVIGWGNLNGIVSSNIYFAAPRYFVGHGVVMGYMVVFLFGGSLLMTLLLRRENARRKRGDRDHWVQGLNPAEIDMLGDRRPDFLYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQZ6</accession>
    <name>A0ABR3YQZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRISE-like Rossmann-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF29">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="1">
        <location>
            <begin position="29"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="48689" checksum="538441F60EA3FA22" modified="2025-10-08" version="1">MPPSTQVVRNDGPFRGLPTYGDDVKDLTAIITGANGMSGYHMVRVLAAAPQRWKKIYCLSRRPPPSNFFEDLGEGAKLIEHIPVDFLSDPEKIAESLKGRVNKVDYVFFFSYMQPKQQGGTLNMWSDAEALAKINGDLIRNFLGGLKGASLTPKRFLLQTGAKHYGFHIGPATNPSFESDPRIDVEANFYYPQEDALSAYCRETGATWNVVRPSYIIGAVRDSALNHMVGLAIYGAVQAHRGLPLAFPGDYAAWDREYCQSTALLNAYLEEWAALTDAAANEAFNVQDGTNFTWGRFWPYLARWFGTTWTPPETDESKYSVVKSRYPDPPRGYGPQGVTRTTFSLLEWSGQPEVKAAWAELSKKHDLALDPFTEVNRPQIFSMTDSAVIGGWALSLSMRKARDLGFHATADSFETAFNTIRDLARLKVVPPPSATAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR43</accession>
    <name>A0ABR3YR43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">rio1</name>
        <name evidence="20" type="ORF">Sste5346_008349</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 20" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="19">
        <location>
            <begin position="38"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="397"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1890347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="489" mass="54729" checksum="5B0986BF11F97EAE" modified="2025-10-08" version="1">MASEDRVASLAGGVANVHISDGGSGTGHKDGKLHLGKEKADRATRDQVLDRRTEVIIEAMVRKELISELQGVISTGKEANVYAAPLHTFDDEDGTHTSTLYRAAKIYKTSILSFVDRERYIAGEHRFRGGGHKGNNRKMVKKWAEKEFRNLQRLNRAGIACPYPIQLKANVLLMEFLGDNDGHAFPRLRDVELIPTEGAANEDDDIALQWRALYVQLLGLVRRLYQVCRLVHADLSEYNILYHNHTLYIIDVSQSVGHDHPQTYDFLRMDLHNIGAFFRRKGVDTLRDRTVFEFVTATPTTSPATSEPEADAAAAAAAIDALYDARPKTETSKGADNKETLAALEVDNEVFRTQYIPQSLHQIYDEGMVARGDGPVGGVEALHAKDSLYGNLLAGDKPAAAEGDEENDEEEDDEDDSDSDSEADSLSNSDNSDDEFGRPRKPRGKRFDDKDEKRAHKQAVKEEKREKRLVKMPKKEKKRKVNTTSRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR59</accession>
    <name>A0ABR3YR59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FRS2</name>
        <name evidence="14" type="ORF">Sste5346_008239</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040725">
        <property type="entry name" value="PheRS_DBD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18553">
        <property type="entry name" value="PheRS_DBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="227"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="511" mass="58164" checksum="A1C40BE6848B3D47" modified="2025-10-08" version="1">MASAKDDLTTAVLRALENVDSIVTNEAFPNEKTIDIKAALDRLRSRSMLAYETLERDEYLLEPEGEQIAANGSHEARVFEALRQAVEGLSVADLEKAVGDKQVTKLGQGKAFREKWIAKTSDGKFKAVATDITDTTRQQLQAIAKDHTYPDAKVIAELRKRKLVRLQKVINFRVRKAEKFALEMVREETDLTADMLASGAWKTATFKPYNFEALGADQNAGALHPLNKVRHEFRQIFFEMGFEEMPTDKFVESGFWNFDTLFVPQQHPARDLQDTFYISDPARADPPRATDADDKKDYKEYWDNVRQVHETGKYDSIGYRYPWSPEESLKLVLRTHTTAISSAMLHRLAAKKGPDGRPPPARYFSIDRVFRNESVDATHLAEFHQVEGVIADYGLTLGGLMEFMEIFFGKMGLEDLKFKPAYNPYTEPSMEIFSYHKGLGKLVEIGNSGMFRPEMLEAMGLPRDMRVYGWGLSLERPTMIKYGISNIRELLGHKVDLNFIKKNPAVRLDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRQ2</accession>
    <name>A0ABR3YRQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Leucine-rich repeat-containing protein 40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007863</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF27">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="428"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="921"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="958"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="428"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="986"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1003"/>
            <end position="1019"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1263" mass="135406" checksum="004B2937EFD03203" modified="2025-10-08" version="1">MGDRTQIPRPSGLPRPASRLPLYSSSTTSSSTSAAATAPAASINPVRPVALRTKPSRESLSGGDLRNPKLRSMPSQDRLGGLSPSSSSSSLSIAKGPLRNASSRTRAVSGEFAKAPPRKTRASMGATPLPSARLADDGFKRPSTAGTLSRRTSAQHLPSRPQHTPTLSNAYSTSPDEELLAEDETVGPAEPESLRPRPSRPRLSLAERTMETLAQIPSSPAVKGKTTAFYDPEAARNSQRPSSRTGSRAGSRPGSSYRSDSSTRSGSRPPSRPRSSSGNDDTTLNFRSSVNSFRSAAPSSFVPIDEVSTPGRSISTASTTTRTLRGRASIGPGVAPGRYGALGGLRQQAEAPSFLPPRSRTPSPEKKLAIPPVTPSALSTRNTAAPGKFASKTVAARPLKSRASVGGLFRKPSMNSMDGSVTATVVASPAATRKSSLASRASSTSYEDTGASNASNASTASTALSIDSADSTGQSPVNNSRKSSAALREQIARAKAARRVASQNMGDNARASPASPLSTQAASFSTGFGDSGLDVEPVVPTDTTFDFGLGSDPFNQNRNAETQAKVVLARVSAARTSGRLNIAALNLREIPAEVMGMYDADAMGTYDGSWAETVDLTRFVAADNEIEMIDESVFPDQTLEELAEMEDSKGNIFGGLETLDLHGNMLISLPMGLRRLPVLTSLNLSQNRITNNALEVISQITSLRDLKLGGNLFYGPLDPSFAKLENLEIADLHGNNISALPLTLSNMTKLRILNISENNFESLVFEPLSKLPLVELNVRKNKLSGVLIEDAVSTMPNLQILDVTSNQITHLVSTTRSDGLALPALQQLLVSMNRLQMLPDMTKWTTLMTLIGEENSINSIPDGFTSLRHLRHADFSSNDIRTIPPEVGRMDNLAMLRLSGNPLRDKKFCTADTDDIKEILASRLEPEPDMGLGPSEEGYILNPQSDMTQNEMKDELRDAVTEMSTKASAHGRQRSRKLSGASAGARSDDDREDSRSDDDFATPPTSRPHSAARSRSQTVSNQLWAVKNGGVLDRSETESSSLHPVISSRVAQEHTIYEIYLQKNLFTALPDALSFFASTLTTLSLSKNQLKGETYFGDAAASDGLELPALKELNLSCNHITGLGPLVKHLRAPVLQKLDVSMNRVSSLPADTQLRDAFPALTVFLAGNNHLAELHPESIEGMLIVDVSNNDIEHLNPRIGLLGGEGGLQRFEVLGNRFRVPRFNVIERGTEATLRWLRGRVPVAEMGAWREANRNGDIDDDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSM7</accession>
    <name>A0ABR3YSM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="452"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="122"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="469"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="801"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="813"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="965" mass="105685" checksum="D3FD7DCA00BF7C4B" modified="2025-10-08" version="1">MSSISSTGSNSNGKSSGRTRPAALTACEACRKLKMRCIRPTATENSESNQNEPCERCRRNKRTCTIPEARPLGRRHGATGRYHGLEKAYRRMQAELKKAQAQKSQLRPDTADETDVPDYAQISDISDIPDIPDITDVPDVSVSVSVDDMPDVSAVPLQRNRNSREPGNRQSANIVEDNFVSPADTIVAATDSAPAPYSYDDPAQQAQPEPEPDPEPDQEPDPEPMSNPLALLADASSDAAQALASVSSGTEATLHIGVGRRLLRRPGYVSLGLRLSRDTLEQGLDVLYAPPSDKHATHANYFKRPSGVSPARDVGPDLDPVDLGLVTMEEATSLFRSYYARFHPINGILDPILHTPTFVRARSALLFTWIMALTAQFEVGHGAASLAKRLRLHGEKLSHHVHACGFKSVEIIQGYYISLLSASPAATMAEERSWLYTMYAFGLGSELGLDKEDKEDKVEKEAETVPAKPSQSMRPSQSPYGTGASTAGPDSGNTDRAAPAPASGPATRPSSDRSERDCRLARNRQRTWLRILLWERANSAARGRMHNFPETALTRNIERWSRHPLAQPADRFICAFILLRRTLADLQQDLHCRAQAQAQAQTPVADIHWVCNLVDATLRPWREAWLPPDDDTDVVSDADTTQTYMGHVYLHARLWTLSFALHRSISHDPAQLHAIRQDCFAAAVQCCESAVRDLQALGVGLYCMLAPTWAMISYAAVLALSLFPTLYTANAGTSSADSELLALVGQVALQLERAGTTPPHRYGIAALLGHHLVSILRTRLRTRHQQSQTTQQGQPAQSLQEQELPTPTTMPYTQQGQQAQQTQQTQATHHLHLPPTQQPPMSMPMATPMSLAQDAYQHRQYPPYPQPDVRADIYTNDAEDGSGRMPMVYHNHEVIHDSIGAMGPMGAIGAMDVDAIGAIADPTVSVYNPFWTPAVASTEGDLDVTGEGFVDLFRDMFGQGLGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTA8</accession>
    <name>A0ABR3YTA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007916</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010451">
        <property type="entry name" value="Acetoacetate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF261">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06314">
        <property type="entry name" value="ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="587"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="597"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="707" mass="76991" checksum="6C1FC25F2D10C267" modified="2025-10-08" version="1">MSDDTDPLNILIVGAGIGGLTAAVGLRAEGHKVTLFERSQLAQETGAAIHLAPNCHGLLKRFSIEPASFGANPLQGIAEYDGLGNLVKDIDLRGAGGMWQHPWVLSHRVSLHNELKRVATSEEGKGTPAVLKVASRVASVDPEMATVTLEDGTIYTGDLVLGADGVSSVTRRCISGDTIKPFGSGSSAFRFLIPRETVLNNPSTAHLATSPQLDGVMTLWYGRDRRLVMYPCVNNTMLNFVAIHPSATSASKTESKSTWSEEGSKSTLLEVFKDFGPVVQDLLSLVDNSGLRLWTLLDMDQLPNWVTGKLALLGDAAHPFLPHQGQGGGIAIEDAASLVALLRAGTPRSEIKDRLALYQDIRMQRAHKVQADTRRAGEDIVDDDQRAVFNVIEFNIYNFTHDEWHNTTHRLNKWLWERNDPSYYRQPSVFGPMPGPRQDSIGRPVDAINGTFKTTSIRFKTSSTYLQTLFPTPAFRFARPGTIVEATFQVNEVDNLPWLGGGGYHFAGLWIHGVQYTKKDGSPLFGSYLPILFEDLADPIVSGRDELGMPKLFADIVGNKQEKSLEIVVSWRGAEFIRLKLDNLHPAPTATDAEKTGPPPSPLAAPPPPDDGQFVYRYVPAVGKPGTPDAEYPVFLPHKGSTTPRVVDMTLASSEASLTFQAGDRTSLPTLHHVSAALAEIPIYGIVKATLELGHGVENLSHAQRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTQ2</accession>
    <name>A0ABR3YTQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrograde regulation protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RTG2</name>
        <name evidence="3" type="ORF">Sste5346_007534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050273">
        <property type="entry name" value="GppA/Ppx_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057512">
        <property type="entry name" value="RTG2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005">
        <property type="entry name" value="EXOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005:SF0">
        <property type="entry name" value="RETROGRADE REGULATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23566">
        <property type="entry name" value="RTG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx/GppA phosphatase N-terminal" evidence="1">
        <location>
            <begin position="58"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="RTG2 C-terminal" evidence="2">
        <location>
            <begin position="462"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="671" mass="71125" checksum="A34CED5EDE9862C3" modified="2025-10-08" version="1">MAPSTNTGADIITLDNYADKLPKWHPDDDNHLHALVDMGSNGIRFSISDLSPPRTRLLPCVYRERAGISLFDALTAVDNSTSSGGRAGDPPALTLPAETIKQVARTLARFRRIALDYGVAPDRMAVFATEAMRRAANAGTLLDAIAVAAPDLSVHVLAPEVETLFGSTGARSGFAVVGNSDTSAGGLMLDLGGGSVQMTYVDPQIGPGYEVAAARAGQSMPYGAARLTRLVASSASHIGDAGSELQLDKKPKHLDAERVRLVAEAKAEADSRATAEAAPKLADDMTAALARLHEMFPSLLQLQQRQQGNKSIDNGIDIYLCGGGFRGYGSMLMHNDAVQPYPVPLMGGYTVPGYFFRDTHGMRRANHELAGGKIFGMSKRRRQQFAAITAVVDALIVALQRSNHTIRSVTFCAGGNREGALMMRLPPSLREADPLKVLVETAAASSSYTRGRADKDVVAAIEASAEALLSALPPLPSSQPAWAPLRPLLALLATHIWERTGADSSANAAFVLHDAVVRNPGMPGLTHQARAVLAVSLWTRWGGGVAPTDKSLLDGLRQLLDRRVGGNSGGSEGDDDLMFWAEYIGGVSAVLALVFPAGPPNAVELASIRFEPTLSTTKSGKKTAVHLNVFVAASRAVGLDLAEELPECFGSVGKLHKESVRLKVHAEKFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU10</accession>
    <name>A0ABR3YU10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall proline rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="954"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="791"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="854"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="954"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="972"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1121" mass="118097" checksum="242878C3BEC89594" modified="2025-10-08" version="1">MDVPPPHTAPPHSPMNMDMGALSATMAAASEPFAKPSSPRPIPSPVSIPPRFDDDSHMSGAFHASGSSPSPQASPRFQHVPPPPPIPDFVFPARSSTSAPSSYSRATGRRPKSVADLHDRGSTLSPGPAGNIPVRTMRSPALPDFSFNPGASLPPTPGHAFLSPPQSPQSPRAIPMRPGGGGHRRGGSEFVGGSVRHGEAFTFMSTSPTKSESGLASPLLSPLKSPAGPSGASGSKPAGPPHGRRGHAHRRSAAISSHDISDILQPTSPNPPPRGNSAPNSPSGFDCKETKSYTFPERTPTDSAKALSITDIEAPEATKLEEVPEPEAATPVEEPVAATPKSAAQPRARVGFSDTLEFIPRPLSLVSSDTSSTMTARPPTGSGNHSVSGSISSIISLNASIAASIERDGISPLVRSPSRSTVTESRPSTAGAVLDRTQSIIGPEDNDDVSPRRRNSIPLLAAMPAETSGTDAAAQALPSPNKTPKRWSFFSLDPFIGGSSSNSISSPKGSCHHSPVFADEPSPKVADSVTSATSHFSTQKTERSVALTEDTVMDDAPSPSKIVTRKPSNNKKKKKVKTWGILGRKSKPRRKSRRAPTPPPVQSQVDSDDEESIEAPAEAIGLAISEPSTTEGFPAPPVVLVTPSGSPSEPRDAFSTWQPLPSPSISAPDDDPSFSMIDLDAALGPFNTPLPRNYEWEAAQRAGGLSKRQLHSAAGMTRFTGPGMHYSHRRAESAPEMPPFNRAGIPRFNSATAMADVFEEEEEEDENKAASGDKTESSTSTKQPEETAPKPTSVHSMSSTSSTPPRQPSEFLDHRPPSIDIRVTSSDGAEGSSYDRGFDFSSAVSDDATSSIALSRRGSGLSGLSDDDKTQPSMGLKSEYSASSLHDDVIVEEDAGSFTFGDDGCDFVMESSSDSTIHSPGRLMKGKDLAPVDVSPLHLPATGSLAPISPYSMAPSSAFPSPRSPMSYDANRISTAPSSVTEDNFQSLLLGEPGPEVRISSDIPSLTSSNSTMTRESAVPHNGPQYPPLGGQPRPYLPSRGNDRPASFTSTAFGRRRSSLASLHRLISTSHGERSKLSIEVQLDSASTTGATDPEKKAKHSKAKRISRMMQFWRGKDEATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU95</accession>
    <name>A0ABR3YU95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF52">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="39"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="58520" checksum="F03D20EBD23ED46C" modified="2025-10-08" version="1">MGGAVGAVPNQDEAHYTTIPNNTKSSWWRDPCLRWNMMHCIGLCGTLFFNGYDGSLMNSLQSINAWQEYFHHPNSNILGLMNSSGFLPGLIVCWIADIFAHYYGKRLTVWIGSGFAIVGALIIGLAQNTGMFIGGRAVMGIGVQGTLVVAPALLQEIAHPRYRSRLSGMYMSIYYFAAIISSSVCRGTHTLAGDKSWRIPALLQVVGPILTIMLTATCPESPRWLEKRGKSAEAKAILAKYHANGDENDELVVFEYRQIQEALLGEELNAQTKYTDYFKGAGNRHRLLIIVVVSLGTNWVGNGIVSYYLSPILNTLGITDSNQQLDINVGLQTWNLLCSTAAALAIDRAGRRLLWLTSTAGMLVCFSVVMALSAVYAQHGQHAVGTAVIPFLFLFFGFYDMAWTPLSYSYPVEILTFSMRTKGQAIFVFLQTLGMAVNTWVNPIAFNAITWKYYGVYLALISLVLVIIYFQFPETRNLTIEEIAVIFDGDRAFGGHGGEVMMGGVATTTIQHDGDLKKGENENVEQTSTASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUB6</accession>
    <name>A0ABR3YUB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007926</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="5">
        <location>
            <begin position="141"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="419" mass="48357" checksum="D1B654560533DE8C" modified="2025-10-08" version="1">MNTADAELRQRVKTAPDPVPAPNLAAGVTAGAPAIVEHPSGKEGHGKAVQILRGVLFALFFFTTVVAIQFTQWIGSPLYFINRDIFYSYMAYTKQLFGIAIATMTNWWGPTTIRISGDESVAGQIRKKTDGRVEFDFPERMVMIANHQIYTDWVYLWWVGYANKRRMDGFIYIILKQSLRYIPILGTGMMFYGFIFMSRKMAVDQPRMAHRLQKLSAKHTDPEGKSYLDPMWLLLFPEGTNTSANGRRKSAAWAQKMNYKDPEHILLPRSTGMYFCLSELKGSVEYVYDCTVAYEGIPRGKYGEDYFSLSSTYFEGQPPKSVNFHWRRFRIADIPLETAEAFDQWLRSRWYEKDAIMEQYLSNGRLPASPTKLEDGSEQPEYIETEVRTQYPWEILQVFSVVGTVYLLYRLIVRFLAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUC7</accession>
    <name>A0ABR3YUC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Multicopper oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007582</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13851">
        <property type="entry name" value="CuRO_1_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046859622" description="Multicopper oxidase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="38"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="161"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="39504" checksum="7E20F70F3A883F11" modified="2025-10-08" version="1">MSPSRRISSWLAVAAALLNFGTATTQAETTVKDFRIGWVLANPDGAFNKPTIGVNGEWPIPQLTATVGDRMIINVHNDLGNTSTSLHFHGFFQNGTNYMDGAVGVTQCAIAPGSSFTYDIHFDQPGTYWYHSHNGGQYMDGLRGAIVVHDPAGPYEGQYDEEIVLSVSDWYHELSGALIDQLINVENPTGAEPVPQAALINDTQNLQIPVQTDKTYLVRLVNIGGFAAQYVWFEGHSMRIVEVDGVWTEPAEADMLYITPAQRYSFLVTTRSDASANFAMVSAMDEELFDVIPEGQNSNVTAWLVYDAAKPLPEPQPVDELEAFDDFELVPVDGLPIFDHVDHSFSLEVQMDNLRDGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUC9</accession>
    <name>A0ABR3YUC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1892000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="4">
        <location>
            <begin position="194"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="473" mass="49860" checksum="6D2A06BF1EC22768" modified="2025-10-08" version="1">MDVQLLVYDLSQGLARQMSMGFLGFQLDAIYHTSIELNGREYVYDGGILAIQPYSSHLGHPFEKVPLGTTTRTIAAIEVHLDTLRPRFTAAAYDLFRHNCNTFTDTFSHFLVGHGIPAHITGMPDAVLATPMGRMLLPQLMQSGMTGGNRGANGGGSLLGLQETAQPATPIPAAPVANGRPSHLHHTLRLPSFSNVDATQPVLFGKVPPLDKLLSKLGDEVAAQPVVHDLRVYLEGKAANTKSVSTPDLASLGKFVRESVTTLPRATLFAAVDLFRCSLADARVSAFFAAEEVDHATVQSVVGVVNSEDVPYALRLVTLQMACNLFGAPAAAARSLLSDAILRAALVQLVSASFLDDAHVSARSAAASLLFNIAVTARKTKTPAQALPADDQVELAASVVEAIGQEQASAGALQGMLAALGHLVYEASLDGELADLLRVLDAAGVVASKARQFPEEPLIAEVGAELLGKGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUR5</accession>
    <name>A0ABR3YUR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="461"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="670" mass="74375" checksum="61688C2319E4A962" modified="2025-10-08" version="1">MSRHIRTSVTVDHTSTSSSRSGSLVDDDNSSYDSRESYTWDDDGYGEVDPTDSASASGDHYQQRRAPARTASRKHTRAQRQAHIPYRTVQAPPQPAMSTDPSEEYATYGARGGYAPHQSAAPYYGHHAQSHVGGYAAPYGGGGGGRSQMVHYGGNYQQNPFAPNAGGGAAYYNDRPQYDMVPYQNNFFGGGPQYGMAPIPPYMYNPPPPPPTEAPGQSQTPAPAEKKPDPEVERMKQQLEILQLEKKAKEEEIKQKQLQEQMRQAAELEFERRMERARKEAEEQKKELDKAKADAERAARERMDAERKAEAEKKAQQEQALARIEAEARAKFEKERRAEEEKAKREAEIAAAAEASLKAKMEAAEAAARAKAAADFKAEIEAKEAAEKKVKEEIEWRKKLEEEAKLKAEIEARAKLEEERKKAEAAKVAEDEKKKADKAMREKIVEETKIKIQEDAKKNEKLPIKFKDAVGRKFSFPYHICQTWAGMEELIKQAFVQVEAIGPHVQEGHYDLIGPNGEIILPSIWEKVVEPDWSVTMHMWPMDKTPPLRNGMPGMHFPPGHPMHQHQRHHGVHAGMPQGRGGMPMPGMPGGVRPGMPGMPPNGVPPRGWMPGMPMPGMMRPGPGGVRMANVVDGDRIPGRHEKKKGSSSKSTGTGFLGFMGGKPVKSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVW6</accession>
    <name>A0ABR3YVW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="335" mass="36471" checksum="EFD79E8FD41AA3A8" modified="2025-10-08" version="1">MGAPPAGSSRAQQFEDEEALPTYTLEPEPSELPAYDEAAGSSTSVPPPPDTKAAPPPPQPLRSMLDVDDGPSGRFLPEDVLPPAIYVLDDTVIYASADSERKPLYKLDWNLTGRLGPRAHWIEFSRMEPKVADPTQHKPRHIYNLNHCSAYTGPPLTEAGATAATALVSFYFVQPTAGPSRRMGCLGFKRESDHWTALPFGIDEQTGVVLPPSKYTAAGGAPLWEARKVQGAACKWVEARPQGDNRPAGDVAMEYDAGSGTAGGRESEPPRLVVTATLTRQKRDALIALWCLRQWATRHQTSAASPPVKEKSESRWKSNSLRWQLGILPTAKKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWZ9</accession>
    <name>A0ABR3YWZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fumarate reductase</fullName>
            <ecNumber evidence="4">1.3.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006808</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Irreversibly catalyzes the reduction of fumarate to succinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF12">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0274">FAD</keyword>
    <keyword evidence="1 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="479" mass="50315" checksum="055BFFE72A0ECBF9" modified="2025-10-08" version="1">MAPSAQGRQTVIVIGSGLAGLSAASAALRSSITDVVLLERAAKPGGNSIKASSGINGAPTRFQQQSSRDLAFFSDTVRSAGGRISQGEPNSARRKRLISLLTERSAAAVHFLADDIGVDLTVVAQLGGHTVPRTHRGAGKTPPGADIVSKLVAVLQKNNRFHLKTGCEVTKLLTRTSDTTTVVGVEYRFDNQLFSIAGPVVFATGGFAGDGDGMLARYRPDLASLPSTNEPRPGMHGLLTSAGAQVVDMDSVQVHPTGFVDPLAPNSHVKFLAAEMLRGEGGILLYKGKRFVNELGTREHVSSTIMGLEPSSGPSRQWDVQVLLDPGACVAAASHVAFYIWKGLLSRMKVSELDEATRETIREYSQAAAGKTSDVFGRVAFGHWVLAGGTEDNDKEVCVGWVTPVTHFTMGGVVINDKSEVMTSTLDANEETAIPGLWAAGEVTGGIHGDNRLGGSSLLECVVFGCIAGEQASAKAVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXM6</accession>
    <name>A0ABR3YXM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF19">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FADE4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="75"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="190"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="308"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="50938" checksum="1B620BBEF8E4217B" modified="2025-10-08" version="1">MSFLKQFPVSAVGRNAVFRPANINNVRLARPLREATSPVPLWSTVSGRRHMASAGGGAASDPRLSLMDASCLSGTQRQVREAVFRVCSDFPDEYWAERDDTGTYPRDFHKAIADAGYIGIALPEELGGVGLGLSEAVTMLQTIAESGAGFAGAQSIHANVYATQPLSRFGTPEQRAAWLPKIISGEWRTCFGVTEPDAGLDTRKLRTRAERIEKPDGSYSYRITGQKIWISSAQVADRMVLLCRTGKGDTDKIDGELTLLCISLDKSKPGLSLNPIPKMGGRAVDANEVFFDGYEVEDGAGALVGNEGQGFRIVLHGLNAERCLIGGEALGLGYAALRRAVAYVGERVVFGKPVGAYQGVAHPLAEAWMSLEAAKLVVYNAASQYDVYKSQGEGKLPANLGVACNMAKYMAAEAAFQACERSVLAMGGMGYARQFHVERYLRESLVPRLAPVSREMIRNFVAEKALGLPKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXR3</accession>
    <name>A0ABR3YXR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar membrane transporter for cationic amino acids</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RTC2</name>
        <name evidence="7" type="ORF">Sste5346_006578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF35">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER YPQ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="398"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="445" mass="48986" checksum="62A3211D4ADB083E" modified="2025-10-08" version="1">MVPPTGPLNLDVEAISGICGSISIACWVVVFSPQIIENFRRKSADGLSLQFIIVWLAGDVFNILGAVLQGVLPTMIILAVYYTIADIVLLGQCFYYRGFTWRDDVVPSKPKHKKQRAVNSAGGSSSSSSSTRNGRPDERTSLLAKNTANNRLIGSVEENGHASGHHHHHHHQERRGSNWSTLSPAMPFVPDLANLDGAAEHTAHHHHNQHTSTTNAAATTNTSSSPSQTASTLQTVIFNAMSMLMVCAAGVAGWYLSGGSNRDDNSSPPSDGGNDNSDLTFNFWGQVFGYFCAIFYLGSRVPQLLLNWRRQSTEGVSMLFFLFACLGNLTYVLSIFAYDGCSGQNRATCTPEDARARYGRYLLVNLSWLAGSLGTLFLDMCIFVQFFIYRVEGADDDEYSEDGEYDEEEGSCDTDVDVDENVDEDSDEERDQRPLLRRNMSSYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXW3</accession>
    <name>A0ABR3YXW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase 2 (Mannanase, beta-galactosidase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BMS1</name>
        <name evidence="6" type="ORF">Sste5346_006630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01882">
        <property type="entry name" value="BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037875">
        <property type="entry name" value="Bms1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="5">
        <location>
            <begin position="62"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="404"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="553"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1110"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="419"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="657"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="672"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1110"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1169" mass="133116" checksum="C0ED3AFC8B4E9A86" modified="2025-10-08" version="1">MEDQAHKPHRKSKEKKKHSGPNPKAFAFSNPGKLQRSAARSHDIKEKRLHVPLIDRLPDEPPPRLVTIVGPSGVGKTTLMRSMIRRYAKETITDPQGPVTVVTSKKQRLTFLECPNELEAMVDVAKVADIVLLMIDGNYGFEMETLEFLNVLAATGMPGNVFGVLTHLDLFRKPQALKDAKKRLKHRLWNELYQGAHLFYLSGVINGRYPDREIHNLSRFLSVMKNPRPLIWRNSHPYAVIDSFRDVTHPTKIEEDELCDRSIAFTGYLRGTNFAAQGQRVHIPGLGDFTVAKMEALPDPCPTPAMEQAAAKATGKTGRRRLDEKDRKLYAPMSDRSGLKIDGDAVYIYRENGFTFDKDAVGVERSEGEELIIGLQGERKLLGETEEGVQLFSKGRKIVAEELNSGRKEQRNARLADNVEGEDDGYDDDGSSDEESDFPNGDGEFDEDEEDEEFEESEFDEKKLGKMFRNRGGDRNGGDDNGEELEFADSDSDLGSLDGDEGNDFDDDEDAAIRWKDNMLERARNAHKRKRPFQVKDLARMLYDTSISLSTVAKRWRGEEEPEEEAEDNIEEEDDFFKKTEEAEKAEDNTEDRSLPVVDNDELKSRWTPDAIEALRSRFTSVKSKKSGGGDDDESGFDDEDGDDDDDESPFGSDAEGGSDSEGDGDFEDLETGEKHGPRKDKAEKAEAENFEDERDKNARRKQELRLRFEEEDREGLNNAKAQARKEAGTTADEFGEDDWYDAQKSLIQKQLDINKAEYDELDDRQRVAVEGFRAGQYGRMVLEGVPAEFVRMFQARMPLIVGGLTATEDRFGFLQVRIKRHRWHKRILKTNDPLIFSLGWRRFQTMPIYSISDSRTRNRMLKYTPEHMHCFAQFYGPFVAPNTGFVCFKNFSASAPINQQGLRIAATGSVLSVDESTEIVKKLKLTGAPYKIFKNTAFIKDMFNSALEIAKFEGAAIKTVSGIRGQIKHALKQEGAFRATFEDKILLSDIVFLRAWFPIKPHRFYNPANNFIGWQPMRLTGEIRRDADIATPQQRNSQYRTVVRQERHFNTLKVPRQLAASLPFKSQIVQTKKQKKTTYMQKRAVVVGGEERKVRNLLQNLTTIRRDVTQKRAAKKEEKRVEHRKAVADAEEKRAAREKRETKEFWSREGKKRHMQAEGGGGGKRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY33</accession>
    <name>A0ABR3YY33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTPase Cdc42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cdc42</name>
        <name evidence="10" type="ORF">Sste5346_006580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01874">
        <property type="entry name" value="Cdc42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037874">
        <property type="entry name" value="Cdc42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="194" mass="21563" checksum="6C7D36B0FA5C8CA5" modified="2025-10-08" version="1">MVVATIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVTSPASFENVREKWFPEVHHHCPGVPCLIVGTQVDLRDDPSVREKLSKQKMAPVRKEDGERMAKDLGAVKYVECSALTQYKLKDVFDEAIVAALEPPAPKKKSHKCLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY63</accession>
    <name>A0ABR3YY63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH:ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NDE1_2</name>
        <name evidence="9" type="ORF">Sste5346_006680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="8">
        <location>
            <begin position="131"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="233"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="354"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="565"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="664" mass="70651" checksum="AACDDC429AC3F767" modified="2025-10-08" version="1">MAEPPSSPPSGDTSTEDALSWYKSQYEQLEHELIEFRESSRELEGELEKDLDAADKRERTLREKAEGLQYEVDEWKKKYKESKAEANAAQNTLEKEITILRDTNRTLQLRLRDTEVANDDFERQARNTTSSLEDLESKYNVAIERGVLLEEEIKMGEQERETLRVDAQRLREELSDLKIEAEILQAKLAKQAEQQREDERVAEEEALAEAAEARARHHHLSAISTDLSVLSVPESPTFDHSPNSTASSPLITTPPDAKSLSAAGSVADAQDLSMSSPPLSDAAAATVSKPLRKQQPVKSSAPIPPLGRTPGPVRKSRLPSSEFGVGATSTPRPKAFSSSISSASGARPLGNRVATASAATRTPASRTTTAGTGTAGPKTGARATSHKLPSSNSLSHIRSLTAQMQRLEARVQSARSKLPAPISTPPRASPRSLGMGAPASALPSTVTIRSRKRTVGSTASSVISGDDSTPTPTNHVSRPAGSKHVPRLSTSGVSRLSFGPLPNRGGGGSNNGLESESSRPSSRASVSSYARPASRNADARDMPPPRPMSRTSLSGARTPLGRPRSSLGSSLHGHSMSMSMSGAVQSLPEDDVAGAEGENFRTPSRRGTYSKYEMEAALNASTSGIPAPAPSGIPMPGSRRQSGANSALGFSSSVSSRRASMSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYE8</accession>
    <name>A0ABR3YYE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Bzip transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007092</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Positive regulator of amino acid starvation-induced autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
            <location evidence="4">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SCOC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019357">
        <property type="entry name" value="SCOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21614:SF0">
        <property type="entry name" value="GEO08385P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21614">
        <property type="entry name" value="SHORT COILED COIL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10224">
        <property type="entry name" value="DUF2205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19622" checksum="262D03FDF3A13D32" modified="2025-10-08" version="1">MDDEQPPTSHVTIPEEETQGNNDSQTPSRLTAPAIARTDSSSASSDGNPSHTTTIHAPVPTRPRLPNRKSSGTIIVPRDSEEASRPMETRLDPGDVRAMSPRRTSEDLEQLGRQTRAEVRKHAKMLQDSLLMIFHRIQAVKEEHDKLDNNNKFLQKYIGDLMTTSKITSTGGGRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYL3</accession>
    <name>A0ABR3YYL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="234" mass="26152" checksum="94D5A23343D58988" modified="2025-10-08" version="1">MATDDKHPDSVTFHEDTSKADMEGGVLAADIPELLRILTPEELKKVGRRAVFKEEIIMMPCLMIMYILNYLDRNNISVAKLAPLHIFLTRLCQDDDREEITPFKGLQMAVRDPKTWLLLSVMYATFTSAGVTNFVSSVVNSFGFSRTITYVLTALPFLLCCVCMLANGFHSDRTGERFLHIVLPLVITLIANILAISTLNIGARYTAMMLIPASYYSSSNVHSPDDPNVAKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYT2</accession>
    <name>A0ABR3YYT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF7">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="386" mass="41918" checksum="D8CBA25E8CB2828F" modified="2025-10-08" version="1">MASTTSSPSRVIRVGIIGCGEIAQVVHIPTLNFLADKFRVTYLCDVAAGARETCADRVVQGTEGKRPVTTASAEELCASPEVDAVLIANADAYHVEHGLLALAQNKHVLIEKPAALCFRDIDRLIEAEKQASGGARVFVGTMRRYATAFEDAVKEVGGFDHVHYARVRDIIGPNALGVSQSGTFPRAFQAGDVSAADSDDRAARELDIQTQALSNEFGVPLNDASKRMLRVLGALGTHSLSAMRELLGMPKSVAGAALTLPGIFAVLFRYETFAVTYESGLSGVPTFDANIEVYSANKIVRVNFDTPYVKGLPVTLTIRERVEDEGVAEPYYQERTIRKTYTDPYTLEMLEFYEVVANGKTPKTSAVDSRNDLELFKIILQAGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYV2</accession>
    <name>A0ABR3YYV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006706</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="710"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="710"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="853" mass="91938" checksum="CECFACB9BBA2DE35" modified="2025-10-08" version="1">MAGRKAAGTGATPASPGSSSTTSTKTKSTTTTAGVSRTHRGLTCANCRARKTRCDGSQPTCKTCEVYRDTCRYEKPPPMSQIVAMARRLQEAEEMVVALKAELAAKSASTSTAPMTTTFSPAAPTSTPQPLTTSPIPKSEDTDMSSTTGTTSRQPSQDLLFDLSVDSNGKLCYVGPTSAVHNPPVIEAHTSPIQTYDETPEDDDRTTSEVRQRKRRATGQQQQTQNKARRPSTHAPSGTNMTTTKADVRALLTTTAIEARAWEAFALGSAAAQTDLPRAALARLLQIHWVWIAPMFMWVYRPAFMRDMARGEGKYYSPLLLIVLCGHAARFEESTATTTIGGSSISTTVPIAASGSSSPTGSLLGDALISRARLLLGAEIHKPSSIPTVQALLQLSARDLAYGHISQAWLYSGMAFRMVSDLGLQHSSSGQLLSLGHLNAEDLEVRRRLYWSCYFWDKAMSLYLGRMPTLVDLPLDASPELLDDFAEHELWSPPPNTGGADGSSYPPMKSHAISCFANTCRLAVILCDIILQLYSRRRPTTSSSPTSIQSLRDRLDAWRAATPPHLLVTGPDRAAVCPPPHILTQNLLYYTTLILLHRPFYSSPVHHAACRQAADHLERLLLLLERTFGFRRITYLMAYCVYTGASVLVQDIKQSHGKDAAAASKIQTFLRALRLGVVSCPLVRRSLDIITDSLGDALAEGQPAEKDVVVVSSSESDSSSSSAKEASVTAPPTVMVDPVITTPAPPHDDPSSSTGTVPSNPLLRNYLPAFPYYHAQLDFFDTSGSGNSGGISTDTSGMGNGGLPQNMPPNNTFGPGSDPYDMAAMDIDAFSLLDCFPENHLDSATAAAWYMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYW3</accession>
    <name>A0ABR3YYW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="5 14">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PGK1</name>
        <name evidence="16" type="ORF">Sste5346_006388</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="5 14"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF0">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 14 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14 16" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1893558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="419" mass="44224" checksum="E2CB2A3AB5BE15C9" modified="2025-10-08" version="1">MSLSNKLSIEDVDLKGKRVLIRVDFNVPLDADKNVTNPQRIAGAVPTIKYALDNGAKTVILMSHLGRPDGRPNPKFSLAPVIPELEKLLGGNKKVTMAPDSVGPEVEKIVADAEDGAVILLENLRFHIEEEGKGVDADGNKVKADKAKVDEFRAGLTKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAAGFLMKKELDYFAQALENPKRPFLAILGGAKVSDKIQLVNNLLDKVNTLIVCGGMAFTFKKVLDNVPIGNSLFDEAGAKTVKELMDKAAKNNVKVVLPVDYVTADKFAADANTGTATDADGIPDGWMGLDCGPQSAKLFADAIDESQTILWNGPAGVFEFDKFAKGTKATLDAAVKACADGKIVIIGGGDTATVAAKYGAEDKLSHVSTGGGASLELLEGKELPGVVALSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZX6</accession>
    <name>A0ABR3YZX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Siderophore esterase IroE-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052558">
        <property type="entry name" value="Siderophore_Hydrolase_D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40841">
        <property type="entry name" value="SIDEROPHORE TRIACETYLFUSARININE C ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40841:SF2">
        <property type="entry name" value="SIDEROPHORE-DEGRADING ESTERASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29414" checksum="A121ECAADEC8D889" modified="2025-10-08" version="1">MVLDGNAYFATATDIVRRLQFVVRKKAIAVGVGYPISEAVFDIDRRVFDMTPPSKSGLPTWKPRQDGGAGVGSSPGQGHAQVGKPKVRYGGAATFQRALVNDVLPAVQDMLPSVPLAEMRKVLFGHSFGGLFTLYSLFTEPGVFDTYITASPSIWFNNCSIKEQEEEFLARGSAVPSKLYITTGTAEEDLLQKPGEDDDWFARRRGDVKAKRMNKNAIELADRLRDSKKLDDVWLQIFDLEDHGSSAQCGLQRGINKVLGEWWIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D9</accession>
    <name>A0ABR3Z0D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RBL2</name>
        <name evidence="5" type="ORF">Sste5346_006265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="127" mass="13873" checksum="A99FF802F574FA8F" modified="2025-10-08" version="1">MPSPSDLCIATKAVERLVKEEAFYRAELAKQQERVRQLAQEIAAAEDPSTLDGNAEFVLKQENRAVDETKAVFAPLKQRTAEAVSTLEEQIAIREADAADDGTSSDDELDKARAVLRTGQTAVAKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0T5</accession>
    <name>A0ABR3Z0T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="573" mass="60303" checksum="75D1E340374FA912" modified="2025-10-08" version="1">MLYRATMCALVLVDVHSSKRSIHNRGIAVHFQNVLAAQNTAPSPGSPDNAAVILASPDFATWLDDEAFLADLLQQLPLSQQKDSNSNETSVLCAVVAALALPQSPKSVSGGPNERPPVSGLSIAYGNTDKLLPGIWQGDDSKAALRSSRGSIGSDLDKDAAVTVEVPPLAGAETDSTSLRVTLPLSNTIFQNGRRSTLLASLWTSGENGLQRQNQESRDQQLIVVPSPSQAVTNVSAPLFPLSEPLKIASGLGNIVRQVFDKETSKPIPAARELEAQIPALLKARRRASPALEDGALAVWGLVVPAQVVPFYEQLKQKLQSEQESSLDALSNDADHAPAAEQQAAAQASAYFTELLATGCRLHRILSGGGGWGLKQGLLSLDPQMSHPAAASLSSVESSSDSASQSHKILGEERRDEEMDDEAMLSFIRSFKNETLVGREVSEAEAAAGEASEGSGVDGVAMPGAFVQFFVAPLSVEGTKVEGETLKSADTGPEWSIALGAHAGYDGSPPILDSKTATTGEVALIHNHFGAVSNHGMYLSAVARSSNSNSGAPSTRTKLDAPNAYVWGSMHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0X6</accession>
    <name>A0ABR3Z0X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF2">
        <property type="entry name" value="B, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="1">
        <location>
            <begin position="57"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="2">
        <location>
            <begin position="388"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="836" mass="93659" checksum="5D7ADAE2D81879E7" modified="2025-10-08" version="1">MTLTVTTTAATASKEAFPKGANWIWLDGFDDAAAAGQFVLLRKTFHLDKIPDQPVAVRVSADTRYRLFVNGQSVSFGPCKSYLEHWHYETVEDIRPFLRNGENVLAARVLRFSSSHPGCMSMIRSALPGFILACTFGGDRSSDIFSDPSWRVKKDDSVSLVDENDWDFRLGPQFLGLNENVDDRLAMATLGWNTPQYDDSEWSTAVIKTARRKMSPLLHPHRLVPREIPAMTEEFARFEGITNTTGTVSDGDWTQLLTSDAPILLPANSTNVVEIQADGHSTAFIDLTCYYDGRRDQSPTIQLLYSESYETPVTEGQQRHKSNRSDFVGGELYGPSDTYIPHSGGTNHYSPFWWRTFRYIRLRITTRDHPLTLTSLTYRATHYPLEVTTTIQTPSPLLTDLWNISLRTLRNCMHETYEDGPYYEQNQFAMDTRSQMLFTYVVARDDRLARKGLRELHASRYLDDDGLVSTNFPSAGRAIRIPTFSLFWVLMVHDHMVYWGDELLVRQYLGAVDGILQYFSEKCVDGLVGTFDDSNSDETWAFVDWVDAWMTPGHGFLGMAVPPAYYSHGAATIHSLLYAYTLLKAAELCIFVGRGDTAREYREKHRVVVEAVRRRCYDVESGLFLDGPGALKQRSQHVQIFAVLAGALSEETVDATTLIRKSLLAPAEHSLVKCTVSMGFYVFRAASLAGVYDECWPTLIQPWQQMMDQNLTTWAESELPNARSDCHGWGATPLYEIVTEILGVECRSAVYIERVLGEKDGVSSLIHVSPRRAVVEEIQSTVAVGGSLGSGDGSKVAETLSIGWKVGEEVALSASRAGQVVEVKLGEATSWETRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Y1</accession>
    <name>A0ABR3Z0Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="16"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="408" mass="43504" checksum="B41045517D9E4647" modified="2025-10-08" version="1">MPGLNPADFPDGGVRAWLVVFGGWCGLFCSFGLINCMGAFEDYYVSGPLADYSQGTVSWILSVEAFFVVFGGLVYGRIYDVVGPRPLLVLGTVLYVFGLMMVSTSTKYYQFLLAQSVCSSIGASAVFNACMASVVSWFLKRRAAAFGVMCSGASMGGVVLPIMLNQLIARVGFPWAVRSVAFLFLALLSVAIVTVRSRVPPRPKPLRVGDYVASFADPLFMLTTVGCFFFFWGMFLPFNYIALQAQTAGLDPDLLPYLLPIINAVSIVGRIVPGIVADRVGRFNIMLCITALSTVVTLGLWIPGKSTGAIVAYAMVFGFSSGGFISMGPTLIAQISDIRQIGIRNGLSFAVQSLGALTGSPIAGAIVSSSNGNFVGMQLFSGATMAASFVIFFAARYVQVGWSPLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2V6</accession>
    <name>A0ABR3Z2V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NFACT RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005757</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039730">
        <property type="entry name" value="Jlp2/Ccd25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049">
        <property type="entry name" value="DUF814-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="135"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="204" mass="24044" checksum="CE261BE0500D9657" modified="2025-10-08" version="1">MVYYFTSTVVDPSAYIYVGKDKFESTANEFHVDKLSSAHIYLRLPEGDSWESIPEDLVKDLAQLTKANSIEGNKKDNITIIYTPWSNLKKDGSMAVGQVSFKDQKKVKRVLVPQRENVIVNRLNKTKVEKHPDLRQEKEDRQRELRKRLQASQLARKKEDARIAKERQEIKYRKDHAYDDIFTEENMEEASNQNRDEDWEDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z357</accession>
    <name>A0ABR3Z357_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="33440" checksum="FAD2DCB4C5F0B760" modified="2025-10-08" version="1">MASNHSLRGNMSQLLPLTQCKIFAARIELDELLHSLQRPVDNVILLFTDEHDAQMSQNHRCRLAEWLFVFKQRYYNLQHEFFLTKLTFDEIKQEKLAEQAVTTLVTSPVSPANRPSLTSLPMELQCMIFSYLVQPPPCKHYFYGATWSHKMIDTDLTSPDLAIKTRLLEKSPAVEMTPDGFLWTLCHASRNVMQRAYSKWIDEMLAHPFCHNDDRVNHRMYADSEEEPATNVRRNRNGNRNVYCANPNWMTGMAFIQWTNADGPLRDDASEYTASDSDVDDDENDDDGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z382</accession>
    <name>A0ABR3Z382_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051106">
        <property type="entry name" value="RNA-bind/splicing_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48028">
        <property type="entry name" value="GLYCINE-RICH RNA-BINDING PROTEIN RZ1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48028:SF4">
        <property type="entry name" value="SC35-LIKE SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045202066" description="RRM domain-containing protein" evidence="9">
        <location>
            <begin position="30"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="743"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="785"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="823"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="893"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="930"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1017"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1087"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="1367"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="1468"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="327"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="447"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1124"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1211"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1342"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1447"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1544"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="542"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1124"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1218"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1243"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1263"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1569" mass="169221" checksum="BD85CB1A2D179233" modified="2025-10-08" version="1">MRVDPLQPPPIWPALLSTVLGLFVHPAAAGMNFTGKSLTDIFWQLEYVDTPTNGNPSLGGQNFTTCCLKAINDAIEIGPDGDLQFVSQFDSWIIFNEGPDQPLDLLVNYSLRGQFPCTAVYNGDSRGAPIVQVNYTWLADTCPGWQISSKDNLNAWLQPLSGFLIPAVIFCLSVPRRRKLEVPRFLFSPDQGGIKSYLLAPFGAILALIMVSADTLVWLCICFGFAGPMILSGLYEAMLDNAVLEYLRLKIDESRLTLDMRCRCLMVILIGNLDLVWNTEDPDGNGGYVDGGTHGGSYISDGAGGDGDDEDDHLNYVGGGGAAGGFDDCHPRGNSAEIPLMPLQGNGAYQSIPGGEQPSPSPSGIPRHGRYDQPGASAAYGQYAPYSSSYRYPPYAPVPFGNNGSPSPSGASLSPGSPAPAVPVTSGEPISTAVAYMPPQVQQFNSIEGAAFGGPPPAGDQGFWQQPNNGRFQGHADVSNAGLQGQPMDAPQVIVPPPPPPIQSAGDHEGQAAPADNNHRDSIIPGLFISPASAGPDSMPLQDPFQGQQQYQQQYNQYPQQQYQQQFQQQQQDQQLYTGAVPGFPPGHVEPSPHISYGVPSGAASPGAPSTPVQHLSAPAHGSMGTPYAGSGFVAAGVIAAGIGVGVSHDANRRLLVNHQNGGPLASPWQHMEEFLYALRLYNDDFPTRQHSPRQYAKHQDCPDGIDCHDDVHNEPPIPRTPETERLIHQVKTRLKTMLHCQYSFGSVIGAPVVFFLGGFIFALLQSLDTLGDEDIAEGLAFGQWYMTIPHIAIISGLLLAGNNPNILEGVLAVERKYRQDNIKFLGLTYGLAYPSCYKVASLWDRGYNKKQWLNTLISTYIVRSNAVYSGNEDYDKDIVDLKKKTTLSLSDWSFLLSLTMLLLGLPYILAFLTAYFTPEIGLSCRSLTFTIYILVQICQIILWLWAYAGPLAVFNVEKPGFFRIGGWLDKRGFYEPYSVRWLVDRGQAVPRNPFKLLRLVWNNPGRLVNWRFLWNFVYYTSQWLLGFIGITAAIGGTAMQLMGVYSADICYVTTPYWFSPLEDRPPPIISVNSADMIRESELMWKPCAITAIVFMSVVSFVGWWYQRRMRDLFQDQVRRIDQNERRDTRASRPDRGRVRPRATSGVPLTVRTLTPSIPSAVPVSAPRHMSGASAVTTGYGGYGSYSGQGGGYGRPYGSLGGGGGGRNSMAMMSGALSNPGPTSMPSMGSMAGASSSLSAQGGVIGPGSGAGSMDGRTPSPMGPGGIGNVPEGGSGQATQSVRRAVLRSAASATAQVARASSTSSTPLVRSVAAKAVRMPVSNLAISARYFSQTARVANESTEETAAAPAAEGAADTRAPAADPTPYGVFVRNLVFDASDANLQEAFEHYGAVKHAAVARDPRGMSKGFGFVYFETAEAQAKALEEANGSFWHGRRLIVLERVRRTSPANGGADRPPRNNLPTRAPSDSLYIGNLPYETTDADLNVVFKELEGLLAVRVAVDRATGWPRGFAHADFSSVEAAQAAVEYLKDKQVASRTLRVDFASPSNSLTRSKNRRGEAVAAEAPKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3M0</accession>
    <name>A0ABR3Z3M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cohesin loading factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCC4/mau-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019440">
        <property type="entry name" value="MAU2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21394">
        <property type="entry name" value="MAU2 CHROMATID COHESION FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10345">
        <property type="entry name" value="Cohesin_load"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="100"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="244"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="352"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="244"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="304"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="352"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="503"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1201" mass="130518" checksum="663E09D47DC82CDC" modified="2025-10-08" version="1">MSGSLPPGQQAYNGQHMVPGSVPMGSMGYSLNGPQMASSMGSMGSSMGSPMGMNGMGNGMSNGMPNGMNSMANGGGLGSPMGLNGMAGLGGLGNLNGGLGGGSQYQQHQQARPLPSPQFYNQGLPHPQYTSPNLMHSPLGQLPQQHQQHQQQQHHQPQQQHHQPQHQQRFQPSPQQNHMQFPVPAQRTPSMSSSNGNSFSFQHNGMSVSPNLSAPISIPVTATVPSPTTNHLASPLQFLPQQLPQLSQQQQQQQQQQHQPQQHQQQQQHQSPRYQQQSLAPMQLHMPVFTGASPGQQSQHLPKQRQQSLSQSQPMQQQHSQPNSQPLSQSLSQPAITQFSPLPQHITPSQLLQHQPSLQSPQMHQHQQVQQQVHQQSPQMHQVPHAHNQLQQQLVQPPMPKPSPQQQHTPKPTKPPKAPKPQKSQQAKKPISLPDPSKQPVPLPPQPEAAPASSITQQKPQPQQRKQSSITPSPMPSPLPTNSPRVSPKGGVQKPAKSSAAVGGAGGKAVGAAGVGAGAAVKAPRKPSVSGIGSSTAKVKPAPKRTPGEAAALLVCIADECLAKAQAAAPTLAKSRNEDRLKEYYKLLATGLGCLDTAVRTFKFPPRIEVKIKIRYASILSTETENLMEAETALQSAIATCEKHRLPDLKIYVQFLFMKVLFRRKPKAALISIQTHIADCSDRRQTYWTYAFRFLKAFFYLQSGNPIETNALENLHGITVLAEQRGDHAVYVLASLLQALALFRTTEPDVVERVQTCMAAASKYQLDESVHIPQLDVLWLLLDLACSLYQKEKALTDKLNNLQNRLEELKESPQWTSDACELLLPLRKDTPNTHTISADTSDVLQPGESNDFLVLTSFSKVKAFVLGFAYSGLTLSPKQQTTDRKSMDYWTEALKMLSQSSASKPPAPIFLHEAIDESRWRANASSYVLVLMGLNAATHCDWAKVQECIKQLETPTAEANDGPLDVLALYLKGVLKQGQGELNDALHLFENSRLALPAVSDGSPGSSSAIASAGPAAAAAAAANAASANEGHLRQEVQLLAAMNRLMIMQLNRLRDEPKINMLVEQLKQTCVNHPNPEIKTAYSLVMAAITTEPPLSMHDIKSHIQQGLNGSTVSGNAQCLNIALNTMRYRLFENVVGEQALKSAKAGSTQAKKSGNILWMSVADGMLADTYEVQGQTAQAQVARQAGVQYANESWERTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Q7</accession>
    <name>A0ABR3Z3Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="4">
        <location>
            <begin position="123"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="32421" checksum="904CD916D1861F84" modified="2025-10-08" version="1">MNEYTARQRRRDPALEPRVVDMTDLTDEEEDGNNGKPVTPPPTTTTQPKQRKTKSKKRQLLEEEDDYSPYLDIFRVLTFLLLASCGLSYLVSGGESYFWGMQNKPNYLKLSWWKMQYNGPRYFTLEELAGYDGSLPDRPVYLSIDGNVFDVSAGRHIYGPGGSYHYFAGVDASRGFVTGCFADDRTGDLRGVEDMFLPLDNPEVDSHWTPAELAAKKAQERKDALKRVHDAVQHWVDFFTKSTKYHYVGKLKREPGWEGEVKPLCKPAQEGRAYREVPTEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7X1</accession>
    <name>A0ABR3Z7X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF1">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540148" description="cellulase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="43"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="341" mass="37032" checksum="B92CF3C9459EA6A2" modified="2025-10-08" version="1">MRFIELLLGAAAVTSVFAAPTTDVATTSVSKQRRKSKFQFTGVNESGAEFGNKNLPGLLGKDYTWPVKSTIDTLTGKGFNIFRIPIMMERVIPTQMTGTINATYFQGLTDLVTYVTGKGAYAIIDPHNFGRYYDKVITDTAGFKAWWQTVAAHFKDNTKVIFDTNNEYHDMDNTLVAQLNQAAIDGIRAAGATSQYIFVEGNSWSGAWTWVSSGTATGMAALTDPSNKIVYEMHQYLDSDGSGTATACVSSTIGRERLAAATAWLKANKKLGIIGETAGGANAQCISALTDMLSFMQDNSDVWSGWLWWGGGPWWGDYIYGMEPPSGTAYTGVLPSLVPYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z811</accession>
    <name>A0ABR3Z811_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045637048" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="24083" checksum="319DF968491B1599" modified="2025-10-08" version="1">MRFTTSILSSLAWYGTTVLANPCKPSTPASSSTSQSSSSSVAPSTSPSPSTVPAVCENLVQNPSFDEGDDFMDHWRITAAAPNGVFGYKRTAGLYCSPTYDATDSSPSPCYYVFNEANAAADFYLYQDDIPVIPGSTYTYTIRYRVSHCSATDAFFLYVNGAAVAHLYLAGEPNAWKTLSATWTAPTTGQDPTVATIGLSNNNLDASVLVYFADISFGTCTHGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Z1</accession>
    <name>A0ABR3Z9Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methionine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MES1</name>
        <name evidence="15" type="ORF">Sste5346_004144</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="entry name" value="Methionyl-tRNA synthetase, Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="Methionyl-tRNA synthetase (MetRS), Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="14">
        <location>
            <begin position="441"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="596"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="633"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1897408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="646" mass="72271" checksum="8F891F8A4987C062" modified="2025-10-08" version="1">MADADNVIRPVKGKKNVLITSALPYVNNVPHLGNIIGSTLSADCFSRYSKQRGNPTLYICGTDEYGTATETKALEEGVTPRELCDKFHKLHKNIYDDFQIKFDYFGRTSTDFHTKIVQEIFLQLWENKWLEERVTTQPYCENHGAFLADRFVEGTCPRCGYDDARGDQCDQCGNLLDPFELINPRCKVCKGLNAPPVPRDTKHIFLALDRLQPQIEEWFAKASTEGKWSPNSIAITKSWLDKGLEGRSITRDLKWGVPVPLPGYEGKVIYVWFDACIGYPSITANYTEKYWQEWWKAPENNVKLYQFMGKDNTPFHAVTFPACELGTGDPWSMVHNISTTEYLNYENTKFSKSRSVGVFGDQAKDTGIPTSVFRYYLLSSRPESSDTQFEWSSFVQANNSILLANIGNFVNRIVKFVNAKFDGVVPEYSTSIKDESFDFAAWVGDVQKLLDEYIFELDAVHLRAGLEKATAISSQGNTLLQYRLDNASLEKEPERTKAVIGYALSLCGLLASILSPFTPSTSDSIAQQLNVDLPLIPDTFDPAFIKPGHKIGKAAYLFSRIDDKKVAEWKEKFGGTSETREAEAAAKAKKLADKEKKKAKKAAARAADAAAKKEGEAATTSKPVDAETVATGEAKELPVREKPVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA73</accession>
    <name>A0ABR3ZA73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="290" mass="32244" checksum="4DC0060D8195D3D8" modified="2025-10-08" version="1">MFALDTHDPQITSADGLKIWAAQAGQSPKDAPTIVFIPGFSSSSLLFDHQFRDEELLSKYCLITYEPRGQGRSEWPTDKAHWGSLYFAQDFEAVCKFYGATKVFLAGWSAGCTISSDVFEHGLGHLIQGLIFMSGMPYMKLFANIDLPAVGKYYMPIQAPSDGDTHGRACADFARCCVWEPNRANMSYTFRSALIGTIAMIPTTVRIEGTKCHPQDPANLLAAAPTQEAIFIVGDEEEIVKPDMMISMYEEMFSKLEVVRVPSAGHTVFWERPIETKKAIVSFVDRLTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAC6</accession>
    <name>A0ABR3ZAC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="26850" checksum="19E153861B5006A1" modified="2025-10-08" version="1">MNSTDPRPSANGSRRMPARNNSVSQANDADRNQSSLSASRTLATTGRSAATNNNASTNGTVEARVAGTLGVTATSSSNNNGGSSYAYTFGTGADTGTNSRGNGTINISYNGNGTSSNNNRYTRNNRIESTADSNYRYNYYKDYQSQPGTPTDNGRDNYDGSGNNGGGGGGGSGGNNGGNNNRNSGSGANDNGNGNDGRRFQHNVNFSFNLGPGVNAGTPEVNIGGGGILGGGILGGGLPILGSGFPFGGRRVPGGFVNISPFGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB51</accession>
    <name>A0ABR3ZB51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOM1</name>
        <name evidence="10" type="ORF">Sste5346_003753</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPL family. TOM1/PTR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010309">
        <property type="entry name" value="E3_Ub_ligase_DUF908"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010314">
        <property type="entry name" value="E3_Ub_ligase_DUF913"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06012">
        <property type="entry name" value="DUF908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06025">
        <property type="entry name" value="DUF913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
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                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="1">Belongs to the SMP-30/CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="SMP-30"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REGUCALCIN"/>
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        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="2">
        <location>
            <begin position="22"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="318" mass="34889" checksum="F199888720F84F91" modified="2025-10-08" version="1">MADNNVQVWEVTEPYLDLHCLLGEGPFYEEATHSLRFVDICQKRIHTVDLAAGPSSLNTLELDSTVSVTGDIEGIDPREKIVVGLKYGLAVLDRKTGQYEYLQRFSNSADVTKSSKPVDYERIRGNDGAADPHGRFWLGSMTDFNLGDFQPEGALFVVDAGGKASTLIRPDLTIPNALGFSPDNRTMYFTHTVDNAVYAFDYDPTSGDLSNERVLYKHTGPGSPDGFRVDVEGNIWHAFYGSAQVLKISHKDGSILGEIRLPTNNITCTQFVGTELFITTAADEEGEGGETSKKYGGAVFRVDVGVKGQPLFKYKLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBL6</accession>
    <name>A0ABR3ZBL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004156</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="766" mass="84388" checksum="1135ABC478BEB941" modified="2025-10-08" version="1">MAGLRVLLCTYCSQTFSKQEHLARHVRSHTHEKPFACRICGKAFGRNDTLLRHARGHRSTTTTTTSDQRPQEKSIDAMDQDTDASSNLNLLNNSAGKSASRDPQVGLPLMATGADINTPQTAAAAATATATATAPYISPANLNLDPKLDPRLQDSSNGHTNSPNFNFQTPTWQTSVDFELDAFHRFMLDTSLGWPLNGSLNGPLDGSLSDSLSAPLSDLDWSQMGVDVPPRAPAPPPQTVPHRQDAVQKHWFISRPPRRRPPGNVAQGVRKDGANKLNVDETYRASLSQKLLLQRIPHEALPSADFLNTCIQMYFTRFNPIFPLIHAHTFRPSAENSLLLLSICSIGSLFVGSPFAAEHGQKIYERVNKAILSSWETVLSSDNKLEAISLTQAGVISQTFGLLSGRPNDLLLAQGLHGTVITWARQCGIFRVLSIEDECGVPPDDVYANWRCWAKKEEQHRAATALFVLDAEHAALFKTEPLMRHSASRLPPLCTDNLWASSTAGEWNKLAPNKYAVQDALPRHPFSVYCELEGITASISEARVLGTLGDTLQQQQSLLQFHHQYLRHKASAVEPFCTEVLWHLAWMTLLADMDDLEVAAGREGHMRAVDSPAAQRNRAWAQSQNAARCAVHAALILRKAEQMQIGTEPAVHVPRALFYAALVWYCYIEFGQDDGDKNEGAARLPNFAEFEQLGVSGPQVLFEAHGFKNTRPTRLQSTVTIGLQGLLSRIGHWGISRTFASSITYMVYGDVQGDYESIVNSPERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC25</accession>
    <name>A0ABR3ZC25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">OLA1</name>
        <name evidence="6" type="ORF">Sste5346_003727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="306"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="394" mass="43708" checksum="0FD4EEA8139C8271" modified="2025-10-08" version="1">MPPKKAVVEEKILLGRPGNNLKSGIVGLANVGKSTLFQAITKSDLGNPANFPYATIDPEEARVIVPDDRYNWLVQKYNPKSRVPANLTVYDIAGLTRGASTGAGLGNAFLSHIRSVDAIFQVVRCFDDAEIIHVEGDVNPTRDLDIISEELRLKDIEFVEKALENQKKKTRQGGQSLEQKKAREEEATIEKILAWIKDGKDVRKGTWTPKEVEVINPLFLLSAKPVVYLVNLSERDFIRKKNKHLPGVAAWIKEHAAGDTVIPISVSFEERLTRFETEAEAEEEAKKLGVESALPKVILQMRKALNLGSFFTVGPDEVRQWTIRNGIKAPQAAGVIHTDFEKTFIQAIVYNYSVLHELGDESEVKAKGKIMTKGKDYVIEDGDILLIKAGAAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCR1</accession>
    <name>A0ABR3ZCR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NWD NACHT-NTPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003794</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031359">
        <property type="entry name" value="NACHT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17100">
        <property type="entry name" value="NACHT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69304">
        <property type="entry name" value="Tricorn protease N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NWD NACHT-NTPase N-terminal" evidence="5">
        <location>
            <begin position="46"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1051"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1492"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="310"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1540"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1659"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1904"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1546"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1569"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1659"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1673"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1910"/>
            <end position="1920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1926" mass="212690" checksum="DDB0940402B055D6" modified="2025-10-08" version="1">MAQLNISSQPAPGVTIDQNDDKITITITTTTTPPSDDGPVGPDTPSLWHEAYVRLREEHTEELVSFEEQVRLAFRPLQRRNSPNALGHSAVPGLHNMAPGTVLGAVQRWISEGESKGDERDEGTERDDGTERDEGTEREKNEARRALLSTKRLFNRNMQESPSAHLAWVAASLCVQTQTLAEKTWPTSDAPGFAYIVARISFYDRLSQLVSSGPGDDEEGDRSLREVLVNLYTAVLKQLVVVLALGRVPRETRANQKKQRTFDGPDMSVGGVSGAMHPIIVLELSLGQDARDKALEESISKLVRLQAPPIALSDMDDGDARETANDTETNDDDDSDDDDSEDDDSDDDADDDNCSDPDQRDNNKDDYSVQSEIQSEIQKLLCVTPVRPPSLQPPPSLALDGSPGVLKDLSRWVSQKDAYQRWCKARSTVDVGVDVDANSDSNDRILWLHGPDGSSTTMLLHALAQAETKKRIADINMDADADIDAGQPRHAVACAFWDWSRDVNGTSVVSVVRDLVWTVLAAQPTLQKHLAEAVRTPLLGGNDNDSTTKALYAALGTSCDFYAMLALLCRIVRDPAFAPTCFVVDYMDELLGDDDDVDDEGDRDESYKIKNGRDGRSGRSDPARNGQKRAWTLRDLVALVHTTCRISGKVAWIVSSSSSSSLSTGGCHLHLSPEDPTFDKIMHSYIRALLQCRPAPTYTLDMLDQLASELTRRSGNNITWSTLAVNLLARVRLPWNAMNVLQRLPDNSAGLGPLLDWIVRDNARDSASDNASGASDQALVNTVLNVTALAFRPLTVPELAALAELPPNVDAAILITVLARPLLELRDVNVDVGSGKVQTYVYFSSQAVLTAHRARLAKATAAPDLHAGMVCRHLRCLARHYGDVRDTGRGQLSLYMKIAWLRHLDRVGIGRIRTGDQLLTGPLTDPLTNGVCDFAARNAGAWLYDLDALGTIAVVRRMLQDLLPSAIEQGQLSPMQAALKTLFTRILRPQVMDMPLADIDRFLCIAGCNIDVDYDDDDLPVLPQVPQISLPGLPSLDSPKMADAAAPIATLEGHTDWVRDTHWPYSSRVIVSISDDDTLRFWDRASCRVQHFTEHTLPGYARQLELSQTDPSMLVAMDRRVLVHFDLDTGAVPVMRKTHAEIVAEWREKQDENAADEELSSFSNIRFDEGSSNDVIVACVEDDLQPREIVLGMPGFNLKEVRRIELGYESLLTGLVDVLAKGPVNALLESECNDAVLADDVQLAAVVSKDGDVLIYNTKLAELQQTLHWSQSKFVNVSYDSLWRMFFTRDERGRLMFHFVQKRGEEVEPREQEPTKPAYMPLIRSYRPPHSNPRTYAFSRDRDEVIFTDTDSSITIYKVIEADADAGNNGNDTRDHITPDTRSIRVTTDTTAPAPDPFTSTLLSHDGLRVATANDKGQVKLWNFPNMATSKSESETSISDASAATIWHTMECTESEINWLTFSSDDTLLLACYDNGKADVWDTNTGERVAVMGGHEMWVRFATFLPGNTVVVTASYDGLIRLWDLESCREVYQDTHGNMDGYFVDEDSKSDDSESDGGKSGDDGDGDGDGDKIDSDQDNRNDSNNEKTPISKRIFVALDRAATGTTGTVAFSPDGRFLATSGQLGHIWDISPDPASNTVLPTGPFVPCATLYWEDTSTQKRRKGRKHKRDSGAEDNDNGNDDDDDDGSDFYDDDDDDEASDATANLHCYSFVFSPDSRSLLGFCSDGRLFVWTRTSSTPSSSSINDDRWQPRAAVLADGFAVPGQDSLWAYQPRRLSVSEDTEGQYLLHTEIGVWVLPSPSSSSSSITDGKVKKVGLQPSPHHPCNVVVTGDHMAILWQNRLLTKLPVLYTPCMPYYFSSYTCDVRSVDGDTSTLVIASRWGREFARQARQEAEENAAAEADFLRRQLGEDDYDDYDADEDRYSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCS8</accession>
    <name>A0ABR3ZCS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA-processing protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019186">
        <property type="entry name" value="Nucleolar_protein_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09805">
        <property type="entry name" value="Nop25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="28778" checksum="5B6A8CA0C479512D" modified="2025-10-08" version="1">MFITRPREKKNPLAVPPRKKRKADFNIEEINFDDSARSDYLTGFHKRKVQRQKQAQEIATEKARQEKIAFRKELKEQRQKDVEEHVRQVNEALRQARLAGGEEVTDEEEDEDEWAGLSDEDDKDKKPAVPEFVDHEEEYIDEDKYTTVTVEAVDIDREGMHALSGRHTSDSEESEPGSDDDDDEDGEGDGTKKKKYKKGEAAGADDKDQKKKKEWPKKAKKKQFRYESKAERAVSRAKNKKGKGKYGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD27</accession>
    <name>A0ABR3ZD27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="68"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="298" mass="32446" checksum="AA6310497522AADB" modified="2025-10-08" version="1">MGLWILEPKSDEKVPGTIHIRRDTERDLGLTRNLKHGTGRHAKTVLVPQPSDSPNDPLNWPQWKKNYMSWYLATGTGIMSGTLNFVNPSNTAYAKYLGTSAAKVSQSVSVALLCIGLSVIISSPAARIWGKRPVLLASNIVAVIGYAIVLAKIRSIKYLYAGRAIHGFGMAGIEYLVTSTIGDLFFVHERGFHLAVWHFGLQAGNSCGQVIGAQIVAAQSWYWAFTYAVIIMSVYTAIFFFTCPETAYIRSSRFNTDVRETLYGERDGESGAGSASDTAVASKEIQQVSVEPASPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD56</accession>
    <name>A0ABR3ZD56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-galactosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="991" mass="109013" checksum="10A265BF08865D29" modified="2025-10-08" version="1">MADDSEYSFVEEFEAFLPKKRSSLTKPRGPIPTTAATMGSAVSIATYPPLGQVSTLAGGSDVTFYAVVEQKGDKETSPLEVNLWHSPTERAAGVEGEDGTEWTAAEFHLVNESGQDVGNKMAGASPIFWALQNESKDEPAVVRHYYRAVVKTSTGGPLHFTVRFRHTNSDENASTWRWVGDEQQVGDGTIILREQTPGTVATGDGNIPNLPPQAVESDVDSTSSTDLKELIGDLNSAFRVTSPRSQASGTQLWELSVPVDAATDDDKDESKYTTVSIGTPWHGNFLRWFSLVRLWAPWLAPRHGRQTIDRELDGVLCSFLSEKDGRHLVFLAVSGIDNVQGLFQGGEANKSQLLLNVRSDSLKTETATVLVAAGDSFESANAAVMYHARSLIHQMTTSGAEDGTKTDQQKDAEEIKKLADEVKPAWLENWYDGLGFCTWNALGQNLSEDKIVAAIDTLADHGIRIANLIIDDNWQSIDRAHPDGQFQYTWTRFEADPQQFPKGLKHAIQRVRKEHPTIEHVAVWHALLGYWGGLTPEKAGGQLAKTYATRVVTRAHPKRRNLPMAGPMTVVDEPDVRRFYNDFYTFLEDCGVDGVKTDAQFMMDTWTSATTRRKLTSTYQDAWTVATLRHFGSRAISCMSQTPNILFYSQLPQNRPPVLVRNSDDFFPDVPASHPWHVWTNAHNSLFTQHLNVLPDWDMFQTVHGYSTFHAAARCVSGGPIYITDTPGKHDLGLINQMTGKSVYDKTVIFRPSVVGRSLDQYVGFHDNVLLKVGSYHGNSAGTGILAVFNVSERRVHEVVPLARVPGVHASSGSDSDSSDTLYVARAHTSGKVTGTPVRADALLTLALDVYQYEIYSVYKVHTFDSGDSNKALHVANLGLLGKMAGAAAVVSTTYSQRDDNGRISLQTSIKTPGVLGLYVSGLAEGKRNVKDSFLATMRGQPIPAHCASVSAQDPHILEIDTARAWKELEFKPMMNNEVQLTIYISVDEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD63</accession>
    <name>A0ABR3ZD63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="7"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="574" mass="61310" checksum="5ED369EBAC45DDE1" modified="2025-10-08" version="1">MMVQHCDLRWAKPAPPLKNKTLQDGSYGHSCVQTAVKNLNVVGSGNSSPLGAAINQFVAGIPVPLFNSGDEDCLFLDVVVPGKALRSPSTSKLPVIVFIYGGAYVFGSKDSYMPDLPFYDGSGMIGQSGGDIVFVVMNYRLGAYGFLAGTTMEREALPNVGLWDQRAAFQWVQDYISLVGGDPTQVTAMGESAGAGSLLHHLVAGGGTLDPLFKRVILQSPAFQWMYDRAGTIEATFQVFARLAGCGQSGDTSTASSQKQTMACLRQADPKTLEEANRALMDTVPAGSFAVGPSADGSFIRQLPVLELALGNYASGVEGFLLSHCADEATLFVTGSASTDALFADFVRATFPNYTHANVVEKILEFYPPVDNTTETPVYSSESAREEAFMRDSCFTCNVRHLTEAVGDDKVWNMQYSVTPGWHGTDLLPTFFNARAGINMSDGWLKDILSVLMPIVGALLLGLSTAVQSYFTSFVTTGDPNTNRVVFDLPSTIQWDHPVSNHSGEQIMGVLNVGDFSFSTINDTQNEKSACDFWRSVAAAVTNLGGYAPPGAVVAQSLVNVGNNPSANYVGGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEC3</accession>
    <name>A0ABR3ZEC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE/SOLUTE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567:SF1">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="186"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="39238" checksum="20C3DEB95B194DE6" modified="2025-10-08" version="1">MSQEAQAPTRVDEETPLLGPETGNGAIRPESNGNGPIKDDNVAGVSVEAQPRSTSWYVWRAVWTLAAALILFVFIKGWIDAGGDVDFDFKDALKRALGSGVSGAAAMVLQVLLLMPLRTIMNYQYRFGHSFTEATAILYRERGLSRYYDGLGAALIQGPISRFGDTAANAGILALLHSNSYLKDLPSLIQTIFVSLCAASFRILLTPIDTVKTTLQAQGPRGTALLRQRIKTNGIGSLWWGALATAAATFAGNYPWFATYNLLTAWLPEPARHPLAIWLLRLAFIGFVASVVSDTVSNSLRVVKTYRQVNDTKVSYVEAAALVVQADGLLGLFGRGLKTRILCNGLQGLLFSILWKLFLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFK6</accession>
    <name>A0ABR3ZFK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF1740-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1127" mass="124280" checksum="689A70659B3B77B4" modified="2025-10-08" version="1">MDIKQRDKHLDIYREAVNDSDEALFSLDTRGDQLIWQFGSNDSRRVPSYNRYRHGRNILGTRERFAFAQEGSKILFGAESTTGGGSIFRDKNNPLLRRTLQGSAKPKSKHEHATSKKAPKPDDALNTDKKATGVDEFVSLSSSKKRRRGSDAGPDSEDSSNRSSSDQRDDSDSSSASLDEGSDAENDDFFAPGDDQSNIIKRKLSELNQRVKEDPQDVDAWLDLVDLQDQQSLLLGNDDVDQNFGSATAPTRSKDEITGISAVKLSIIESALRQVHSPSVRERLELAMMREGAKVWALKRLAQQWADLARDHASGSGLSFLLWKARLDFEMTSLSTLTVDGIKLFLTDRILALEKEATAAKDDITKQADIYSQIIYVFLRATRFLYDSGFRDIAAAAWQATLESSFARPATEVEGASLGQFWDSEIQRIGEDGAQGWRNYAAKVQAGEDAEEALLDYNVQNQTLPTLDFAKLAEAAHRSEHYDMEEYKPLYEDWVVAERQRADFAKLPARVIDDINDGGLEDVFRVAVFSDFSTFLFHIPDSVLPAVKPFLVDAFLLFCQLPSAFFTSTWIETARNDPFLAIVVLSEKGNINDIKLKPPTEIPDAALNTAGRDPPDLFYDGSRIVGSSDVLFSLPGWFRYLPEWLRLQDPTASEAPVSPLWVANTLRQLVRSFGFGDLAPYSLAVDALVNPAGIKRAARTLIKQDVSNTALYEAYAQAEAARGNVDVARTVLASATASNSIADIEAELSLRLAWAWIELEGGQKDDAIRRLVVQSLHSEDVTSSSEAASEANKPVSPAELLRLRHTLRTGMEFGLSAGHARRAALFAQSFVLLEYLSSTDSDRQLSQKQRSKQGNLLAAVAVATAFSKDMQSRAYGATTIHEQFLQGVARIIYFHATHGSYRPVDLQAPLQKMVTLFPRNGIFLRLFAWVDPTSASGLSRLRPDNPLQIILDTAVLTRDNDCPSSRAFVIRQALQSGHGQGHAARAAFERALGANHGSSDYNLACFGNARLWQAFVHLTAVESMASATVAARSDGRGVRVRGVDKKMVALAKDVYYRAVRACPGAKDVLLEAFGPNTGLVATSSEAGMSASDLRAVYQTMVGKGLRVHIDLVEAQDRARQAFKRRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFL6</accession>
    <name>A0ABR3ZFL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="830"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="915"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1364" mass="142468" checksum="C8BFA2879230C185" modified="2025-10-08" version="1">MDRDDAASLSPPTRGAVTNSSFSSASTTSSSPPGTATSAPITASPTAANTTPVAATAAPLARSVSQTSAASSTRSHRSLRRGGGNGTGSRTGSRRASSRVPTRSSSQNPQPFTHSSQVGGYAGSSAASVTSEDSKSLTSFPSFSPKAPSSASPPLLPTSQRPRLAGPTASTQSLVDSLLAADERSTQSLLLPVTAPSTSTASTSSITAAVAAPTSSLPGRSALFDDDAPAIIPSDLHLTDDAHVARLIGKHGAVTLVRQLAEDLARRDTQVAALRARAADRERCLRKIILECGLSSLDLETRLRTLEQEQEARLAAAAANTSIPAAHARRVSDLLGDAMSDHHSPRQVSSDYYYNDATIRAASSAAGALSAKDAANSKPASSTGTSRGWKDYLWGGTTKRANGGSSGASTPVTPQTAQKKTTAIRVTSGGDRRPTITEDLFQPPTPSTSTDATADDNTRPTRSASRASSVHSAATSQSGRKPSLASLALRLVGGGGGGDSQDASGTESTSASAAASLRNASGVANPRRPGPPATTIGRSGRASTLQGGNGGSVGPKSLMSMRRTTSSAVLNGAGAVAALNGGASPQAIPGRGIGGPGNRPNGNGHKQQGSSGGGSNERWGGEMMDASPASDGAAAMRRTTYFPVEMDTILPLDVQPPTLTHMYNRYNSSGHLIDRFGFIYDQRRKKRQREAAQVAQIAQVARHNKRGSRHSEMLDTAGGRASRNGRPSPSQLVGCDNEDEADMVVVEADQASIGDASSLKNDNDADSTHRPPSINLTSTSAPDKDSAAGNAPPGSIPKRWQDYLKIATFPTELLSHTPAMSDSRIEVITEDGSSSVSGGDAAGPKSPGFITSDGRGFVPPSTGAMAAATTAATTTTTTTNATASATSLTGLDTDSIASSTNTADAPADQKQLVKKKQQVQQQSQPAPPAKEDVEPVRLLLQQLSELHDTLQKERTVRWNEFLRKVRAERRREGEMMALAAVENSNNGTTNANSRFLHATAIMPETRLADGEIVGVAGLGNKGKLGRAKWNEFRALVLGGIPVVLRAKVWSECTGATSLRVPGAYDDLVAGRDEGDEGGPGAEDRADVVAQIQADIYRTLTDNIFFREGPGTAKLNEVLLAYARRNPDVGYCQGMNLIAANLLLVTPSAEDAFWLLASIVETILPVGYYDHSLAASRADQQVLRTYVADVLPRLSAHFDALSIDLETMTFQWFLSVFTDCLSAEVLFRVWDVVFCLNDGSVFLFQVALALLKLNEAALLACETPAEIYTYINHQMTNHAISIDGLIQASEALRKLVRREDVEARRATAMDAERALVVARAAAVAEAKATRQQKIAAREAATAAQEVAAATKSSIISAGEEAVAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGU4</accession>
    <name>A0ABR3ZGU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF5">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="247"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="635"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="663" mass="69754" checksum="FCFC216987F39305" modified="2025-10-08" version="1">MPCFKGIAVSIHANGAPLPEHGIQKQSRMSRINSYIPVPAPQLSSESGKPEGAKFAISITLLTPGLAIPYSTPKATDANPYPKPHVVGELPSSNSDSKFAGIVTPYIPMTNSENETIAAYIYFDGRPKEEVATLLRPGEETWVNSRWVQVPNSEGGGLAEREFLFREMGLERWLNGLDLEGHDAAAKLEKRRQRFEKRRRRQELQQKQNGSSTTPGGTHRRKSSASRDLRYGGADEQSPVEALEDDDLSDDSLSSDDEPPEATGQIKVAMFRVLASGEIKKGEYSPQFDAHDDDDAEGSGNGGGGVDADVEHTTSFAKPKTLDPKTISTQTVTGIDGPDKPYATFTFFYRGERQLQKVGIIPSAKNAQQTSTDAKRKSAQLDFSSIGPLKTAGTVGFSTFRDHENEPARQKKTGHKRNGSVANANNAMDEDSDDDDDDDDKILGKIDDADDKDVSKSSDRLAPEDAQFSGELADGVNRIRLKRQHSVDPDSATASSNNFRKSPSTGPFGGELTPTEGSGATPSASGLASGVASAVSGGAGSASGDAAGLSTSANSGSLFGKSLPDDSAIGSPLKRHRASVAEGSDSDPRSVFSSGAFPPALGDILAKAEAAYGRTGGSNAQTGSGLGSALGGSLGSTLGTSPTATATAATTKSPTVKEEEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIW8</accession>
    <name>A0ABR3ZIW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">dTDP-fucopyranose mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fcf2</name>
        <name evidence="5" type="ORF">Sste5346_002877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="85"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="206" mass="23605" checksum="7AF797F7BA7B5A34" modified="2025-10-08" version="1">MATTTQDLTESQIDALLREAEERLAEKNDAVVLAASGRPFQVAVAQAAKNEAEEALASKEIAARKTDDVTIRIAQLEKKKNKNDQDNAGPDWFGLQKTDLTPEAKREFQILRMRGILDPKQHFRKDNRKNMIPKFSVFGTIVEGTAKGERDRLTRKQRKNTMVEEVLASQEYNQQFKRRYNKIQEKNASGKKGFYKKLVAGRRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJL6</accession>
    <name>A0ABR3ZJL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">YFH1</name>
        <name evidence="14" type="ORF">Sste5346_001971</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00904">
        <property type="entry name" value="FRATAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="218" mass="23821" checksum="3838116F90A2B9F9" modified="2025-10-08" version="1">MPRPAISAPSRIVRRLASTTTTTTTSTQPLFSRSACRQCLRAPLVAPSATSRRIFSSTAPAAFRQSVARLAQSPQAASPSVSAYTPQSTAEPAAMTESEYHVLADEYLDRLLVRLEDMQDAREDVDVEYASGVLTLAFSPNEAGARPRTYVINKQPPNKQIWLSSPISGPKRYDWVLDVGASGDGASGQWIYLKDGSALNDLLREEMDLDLDAEWEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL72</accession>
    <name>A0ABR3ZL72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab GTPase ypt31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YPT31</name>
        <name evidence="2" type="ORF">Sste5346_001960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="212" mass="23173" checksum="B5B4D0CD879DBD45" modified="2025-10-08" version="1">MANDEYDFLFKVVLIGDSGVGKSNLLSRFTRNEFNLDSKSTIGVEFATRSIQVDSKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDISKHQTYENVTRWLKELRDHADANIVIMLVGNKSDLRHLRAVPTEEAKAFASENHLSFIETSALDASNVELAFQNILTEIYRIVSSKALDSGDGAQATIGAGTNISLSKPAEDAAGKGGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMN8</accession>
    <name>A0ABR3ZMN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TRP2</name>
        <name evidence="3" type="ORF">Sste5346_001814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="2">
        <location>
            <begin position="55"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="1">
        <location>
            <begin position="254"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="544" mass="59366" checksum="A2945012AC373FDE" modified="2025-10-08" version="1">MAAMDGPDVIVPSLETVKSVLAGVTQTAKAEAAKGSASSYKRPNLVPVYGQISSDLITPSAAYLKVSEHSKSKYSFLFESAATERVGRYSFVAAGPRKVIETGPGFGEASDPLPALEAELARFSVAHVPGVQLPPLAGGAVGYVSYDCVRYFEPKTAREMKDVLKIPESQFCFYDTIVAFDRFFGIIKVITYLNVEPTGEGETYDDAAIEAEYRRATGVINELIDVLNGPETPLPEQKPVELGREYTSNVGQGGYMNHVTELKKHIVKGDIIQAVPSQRFARPTDLHPFNIYRHLRTVNPSPYLFYVNCGGRFQIVGASPELLVKAEAGRIITHPIAGTVKRGKTPEEDEALAEELRQSLKDRAEHVMLCDLARNDVTRVCDPRETRVDRLMVVEKFSHVQHLVSQVSGVLRPECTRFDAFRSIFPAGTVSGAPKVRAMELIAELEGEKRGVYAGAVGYFGYNSVAADGVTTVDGGMDTCIALRTMVVADGVAYLQAGGGIVFDSDEYDEWMETMNKLGANMHCITSAEQLYARRQSKQNGSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC7</accession>
    <name>A0ABR3ZNC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="571"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="814"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="924"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1025"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1399"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1630"/>
            <end position="1788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="832"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="949"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1074"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1114"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1128"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1399"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1456"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1647"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1698"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1710"/>
            <end position="1719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1788" mass="193898" checksum="C1F668F90C5AE7BF" modified="2025-10-08" version="1">MDHGPESKKARLSSAGSSWATPSGPSLVNSNPSSSSSHLYQPHPHHQHHQQSYHHAASTHSPNPSPYPAAPHQQYLHSQQPAHQQHQQQLHGRSPRLPSPRNLSPRLPSPRHSPHYTLQHQQPPPPHPSQHPSHPSAVGPYQAVHPSASSPSSSAPPGSHTNGPIASAAAAIDQRPPITSSPAPPTPVSAHSFTNTTTLPPPPPTHNGINPQHKPSHSHSLSQPRTYTAHLDDRRHHEQDPYALGQDHRQQEFHPQQQQQQQQPPPPPDYRLPSRSPAGAASGLPPPPHNAPPYDRVDKPQHLQSVDDDLARNRPGSVASATGMRSQQQPSMPPMRHPDDNARSMSYDNFAHPNMGGPGQPPQSYPPPYASQQPQPPQMHHVPSQHQQHPPPQPQHPHHQPYAQHTPQPPQPPPPPHHGHGHMHPGGQPQQPSPSVTPQGSQQGPNPQYRQPSYPSTTAPPPMGHPQPPPPPMQQQPPMPTQPHQPSPTQQPPALQPHPSQQLQQPPPPPPQQQQQQPPPQLQPHYEQPSPSQQQTPMFNHASVPPQSADILYPLSYAAAGKKKAQRASQACDSCRSLKAKCDETKPCKNCREKSIECKYRDPIPKQQDKVTADILDSISVLRNDMDTIRHDFHNGMDTMRKDVMGILRQLLARPVGDPANATGASASMDLRGSGIASSADAMDLVGGGSSSEAGILPAEPAFPSTVPEQPPLSSNEAERITRETQGELNAVSDFTGPSVTPTDSAIPSNHTTLAGLLLTWPTIRERVHHLLQKEGIHHLLEYPLRQEEQRGSIRVMGRGEGFDQKMTIRVSEHVTSGSQPGTSVAMERGPSNLSNNSSGGSYDDGSDSVRYPGEIWGQLGGWGQTGAYGASSNVELDLDPKTVWKYVKSYEANIQNMHPLINPKPLYAMVTMFLETLPRASSSTSQASRSTWGGPARAPVAAFAGTPDMSQAQSPTAEGSLKRKRSPFPEGYSGPGGTGSTPVTPIIPLRPGMPFRNAESALVLSILALGKICLYQQGRLPDVVPENLEPESPPPTSSQSSQPSPVFADANIHSYNANPSVNNGYSPALSVHDSPTSSPAMGLGNTPSRRTSTQGGGGGPVPWANATSGAAQGSGSFLPPSSSGAGSAKGGNGGVGSAPSMRRNVDDIPGMEYFGAAMEIISTQRAGRELKHVWILILECLYWGQIGRPVQSLEAVALAGRLLLGIMRPSMHRYKTILMALQEHSGKIDQFGNLVQLPEDKNVQHRDNPFLLAYWSCLQLESDILAELHLPPSGILTYEKHFPYPRIDLLAKHGIEQRVLESYTAQLYVRNQLNDIHKTLYHGDFNGEPNFKSIEMYSGLLSTHTWVPPRYAFKDTDPPPNEILHARLRAKYWGAQAIVHRFYVRRILELNHEKRVKLEEKKRKKEEASRVGKLEDMDGKVEKEETDTVDAKTAVESESQGADAKTPSAILSQEVPVGGIPGGPSVRPEDDDSPFSPKSIALARRGIQALIESTRAFHGLPDRRFIITNVFGTAHAQWGNLLILDSIQHDPVLGRYISEDLVNDLFRKTIAFFEVVSQPSSSLGSDLRILKGLYEMRQKNPVYIEQAKDLPVTQGLPSEATMTYTSDDPQLSMLSANLNQMQELYPYVSDAPSTDTVPGPTPVPASSQSQSQSQSQSQSQSQSQSQYPSRVSPLGPPPLPIPVANAAAQAPVYHDGSPMQMSPMASSPVQHASPGTIQRHTHTYVSPPAALADGSSGGGGSSSMPSPSQARLPGMQFGPPAAVKTPTTPNESAFPHHLPPYNRRPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNE4</accession>
    <name>A0ABR3ZNE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar ATPase assembly protein VMA22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040357">
        <property type="entry name" value="Vma22/CCDC115"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21730">
        <property type="entry name" value="Vma22_CCDC115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="23910" checksum="7F706C9AF311B15B" modified="2025-10-08" version="1">MTSEHIDGLLARYLGLLHEYTELRSQLSTHQSSMFGNLARANFSAERGFRYGPDHFDGRMQALVRLSLSEDDSGSEPAPSFAVTRPKKEVEVEATDDVMETKDAGEKKQEDETDTTKNTTEKPRPKKSSKKKEPAGPRDPLQWFGVLTPMALRQAQSEAIEVIDNIVPRLTTLSAEMAAVEIEVRRARKKRAKALGLQEKEGKSTAANATEAAVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNG6</accession>
    <name>A0ABR3ZNG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aldose 1-epimerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09019">
        <property type="entry name" value="galactose_mutarotase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047215">
        <property type="entry name" value="Galactose_mutarotase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="37844" checksum="483DF216E2C1565F" modified="2025-10-08" version="1">MDGSAFTFLARGAIIQHFELHGIDIVQGFPTTELYESHNSPYFGETIGRFANRIEGAAIKVPGGLNGKEAYPLAANNGVNALHGGVEGWGKKTWDGPSPVGVNREVPSLSPSTLDKGGETVQFTLVSPDGDEGYPGTVNVSVKYSVGKQNLPEKEGVEATVLVIEYEAELVDGAEETVINMTNHSYFNLGNLPTIEGTVAKLGATKYLPVDAGGIPTAGPSTFEKVDTAQSFILGQSEPDIDDCFIVNDKPATVPIDTRGEPLSRHLEAHHPNTGIHLEVYSTEPAFQFYTGKYIDVPAVGGLPARIARSGFCLEPSRYVNASNVEDWKNMVLLKKGGGKYGSRTVYRAWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP41</accession>
    <name>A0ABR3ZP41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050328">
        <property type="entry name" value="Dev_Immune_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373">
        <property type="entry name" value="SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373:SF275">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="563"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="563"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="641" mass="69204" checksum="A694DD56D57B6C58" modified="2025-10-08" version="1">MATQQPAAVGQRRSYDGNLCTVRYVGEVAGTAGGTWLGVEWDDPTRGKHDGVHKGVRYFTCSQRSRPPPVVLVGDVPHPALAAAPTTPASFVRPTRPADPPRTFLEAVRAKYASEATTDATEETRAGGTVPGRQIVISGKVAEEVGFDKIRRQLAQIETLKVVILDGQCVLSAGDAGDGPNAVSQIQTTCPSITELDLSRNLFTDFATVATICGELPRLRGLRVNGNRVSVAEGSAYLGAFDGVRDLALEETFLSWAEIGHMTANFPALTSLAAGSNQLTSLTPALPTASLSTTLTTLNLEFNDFTALSDLASLSELKSLRNLHLKGCRIAQVKAEGAPIFAFSPTLTYVDLSYNLVTSWSFVDALPDVFPGMVSLRFAHNPIYNNPNLDSEPTSSAATANSTAASSSSSSTTASTEESYMVAVGRLARLKTLNFSNITPTDRANAEMFYLSRIAKQMAAVPADGSAEAAVIARHRRYAELCELYGEPAVVRHAEINPAFLEARLVQVLFSLDKEGQEKSAAIPKSFDMYAVKGLAGRLFGRSPQQLRLVWETGEWDPVAGVDEEYEDEDEDEDEDEEIGVGDETKEVVETKEGADSNDVDAADPNLKGRWVKREVELKDSPRQFGFCVDGMEARIRVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ29</accession>
    <name>A0ABR3ZQ29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Translin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tsn1</name>
        <name evidence="9" type="ORF">Sste5346_000707</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14819">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="28716" checksum="2BC8E85567DBDE94" modified="2025-10-08" version="1">MINPRVFESLKAKAEQDLVVRAQLDGIIETLERNVAYAQGVLSRVHSTPRARYPTDLLPAVDAAVADEVATVRSLSEVASAHPYYKFNHRWSRHLQDAIFTVLLAAWLGGVASLSNDSTSPAVGRLLTLEEVGEVFGVPVEINHDAFHIALEEYLSALTALTDELGRLAMNAVTLGDGELAVRISKFVKDLHAGFQLLNLKNDFLRKKVDGVKYAVKKVEGVIYDLALRGLLPAEEAAEKKEDAPAAATEAASTATPADSKMNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQJ5</accession>
    <name>A0ABR3ZQJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Argonaute complex, subunit Arb1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018606">
        <property type="entry name" value="Arb1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09692">
        <property type="entry name" value="Arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="67614" checksum="DC11D959BBB482AD" modified="2025-10-08" version="1">MPSVVDAQTAAPGIPTITAAAPPPPKSVTFDVPVGEEGEQDDLDNDDDTKGNLYEDAPKKEGGDDEDEGGVLIGPDGPVALDGPDGPFVDVPDGPVKGSAVDEVVDIQEATVSGKKKKKSKSTAARGPTALPKRCGTGFEEYYADPPLTIDEYEEEMDLYHATLNFDERIETCIQRYRARRRLDNDRTNMFNRYLKLGGIDCTPRMFNGAAGMEEEESLTKDDVRALTATDVVSRAGSKNSKFYASDNADLWTVDFAGVAAGFLSVTLRNIGGSNERLMNLGIDVVDNFLRYLQLHDVCPEYADDIKASREICKTAKVELPNLLTALPLMPGQFNLACTKLFFKDDAYSHEQMMASHDGLDPRAVLTNEDWDPEYIFRTTVAIQDLVIGTKAKKMAEADMSSIRIVNSREIEVEIVQLIWPDKELKERYAKAIEEGEKQKTEKEAAKAAEKAGDKTADEASDEATDNIIKRAGVIIIKHYRIEEGVANRPHVSDEELQARGGDAFFIDMDTMDLLRLGMKLRVVVHELNCDLNFVSVVKEMLPSFYLYLPQELMVDWKEPKVNDREGPSVNNPDAEAEAANEDMDFEDDEDEKKDTNRKKDKTEGKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQZ5</accession>
    <name>A0ABR3ZQZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pre-mRNA-splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001003</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17935">
        <property type="entry name" value="EEXXQc_AQR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048967">
        <property type="entry name" value="Aquarius_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026300">
        <property type="entry name" value="CWF11_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21144">
        <property type="entry name" value="Aquarius_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038901">
        <property type="entry name" value="AQR_cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="6">
        <location>
            <begin position="36"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="7">
        <location>
            <begin position="505"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius insertion" evidence="8">
        <location>
            <begin position="734"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="4">
        <location>
            <begin position="842"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="5">
        <location>
            <begin position="1153"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="615"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1431"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1431"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1476"/>
            <end position="1492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR038901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1492" mass="165058" checksum="B73B9EF028F4A6ED" modified="2025-10-08" version="1">MPPAKKLKSGAGAKAKGGKKATAKPPAAVPEGESAFAQLAKEHWLKGGKLADKVKVKNDVIKAGLWDALEEEAFAFQSLLSLETLQTLEGYLWPGYNEDSSDEHVLLIVLIINAKKREHLDTWGVFADRPLDFASFFRRTLTLSLDTTSFSLAIRAHILSFVIHAFQSLDTAIVRKECAPLVSISTWHNISNDARRDELLDQTGHLRKQWRAAAKRFDAGDADTQSRLRFDRSWLYTLVLDFIGVLFDESGAEDVVRYCERFVEFLSDLQSQLPTRRYVNALLQDLHVLPVLAVSPVVHDEANGLLRDMAALLAHYTYFSVDDQTGAQLSETEAYDKHCTRLAVLQRLALKHFKEKLTVLALSNYGSIDKRDELAALLAPLTDDEIAQLAGLLHLRTSYPASCKVQIGRKFLLEALLATFEKRPTFQDEARGLSIMPTEQNIFDTSLARSEGYDGSQPMALPKLNLQYLSVGDFLWRSLVLYRNESFYGIRQDIETALLRVEPTFGNAGETRFTRVGKMVMPIQKMTIAQVVPPLVGDDKPSLVKAEIVIDFRGVKDFMRREWEGLRPEDTVFLVAVNASVAKSAADGTSTATSAAQRLGITSIRTAEVLYPMESEHGGRGQGFQRRGRGGRGGRGGGGDRGGHGHRNTVKKLQVKLDPAAFVEDTAQSSEGAPDIYDTFNLVVRRHARENNFKPILDSIRSLVLSDVPLAPWLHEVFLGYGDPAAATYKHLPNRIKKVDFRDTFLDWHHLIESLPGKTVEPSDDVTGSFGPPYVLGLADKPPAAEVLAPAKPASKKRRRDAEPALIADVETLKVSTYTPPNNGPYPVDAPKLNSVRFTPAQTEAIMSGAQPGLTVIVGPPGTGKTDVATQIINTIYHNFPEQRTLLIAHSNQALNQLFAKIAMLDIDQRHLLRLGHGEEELALDGASFSKFGRVEMFLENRNQYLQEVTRLAASIGAPGAHGNSAETAGYFNSVYIEPAWTKFNDVAVHTDGASAADIVQAFPFRNYFADAPQPLFPEDADRDTVLDIANGCYRHISKVFAELSDVQPFEILRRDRDKANYLLTKEARIVAMTSTHAAMRRGEIAALGFKYDNVVVEEAAQITEIEDFIPLALQKANATTGEVPLQRVVLCGDHLQNSPIVQNGAYRNYANLEQSLFSRLVRLGVPTINLDQQGRARPSIADLYRWRYPGLVDLPHVQTNPAFLTANAGFRYDYQFINVPNYRGRGESMPSPHFVQNLGEAEYAVAIFQYMRLLGYPASKITILATYAGQRALIRDVLEYRCRKSPIFGLPKVLTTVDRYQGEQNDYIILSLTRTSRVGYLRDIRRLTVALSRARLGLYIVGRRHVFESCPELRQAFQILLQRPDKLALVTGELWPSNRVIADENKAAAGGTLANEVAMEGVEHLGQYVYEMIQTKMQQMEADKAKAEGVAAEGGAASEDASLKLLPAPAREDDGEDIVALPGGDDDEGPRGEDAGDDDGPGAEEDEDGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR88</accession>
    <name>A0ABR3ZR88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="134"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="682" mass="74711" checksum="B1997A348DE9F24C" modified="2025-10-08" version="1">MSALKSFITGKPSSSSSSGGGGSINGVPNIGVGGGMAGGGGGGGGDGSVNVVDGGQPDLVRAWEIEAREQRIRAQMSEQAHVYDTNRMFTYLKQMGASPKQKVNTVDQMLIFCNSLCKERHAAEEDSRLKSHKLGEANAEIKFLRSDVKDALNDVRQAQIETENYRRKYKENKEKLEKADFRRDDAVAKVTRQMKEAAAAHIVDKQQSEAQLRMQLGVLESQIHRLQGEHAAALKQLEEKHANVLKDVAATHEVAQKSLHDDKEREIDEIIDAHEAETDILKEKVRELAADLISQTDDFRPATDQALRIKLLDLRNRIKNITVPNNLHLRIESSGGSGEGGDGATTASATHQLPPDLDPTGFVSRHGSRDLQYILRGLVWNVLIDAFFSAPFGFGFLGPDPQRNPGRQQLMEIHRAWSRLYEGQQPYRYTYDNDEFAMYKRDYNANKLRSAVFQSFLPVVFPEKAAARQQQMMGGPGQSSDHQTQQTLTLNQLPPLPTAQQSQHQPGAALWPGQFQAFQPGGGQAPPPYSSSSPPPPPPRRGGGGSVSGGPEPGVAIWHRQHCESVVASIKQLLDRITGYATRPDALEAVPAIVNLAAELGIEFGVQRAQVWLVMPKRNDLVQAGPEYQDCLGGTSDNNDKDHGRDLKVDLMVSPGIVRIGDGRGDLSIRKALVSCEVIPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRA5</accession>
    <name>A0ABR3ZRA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM3</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MCM3</name>
        <name evidence="14" type="ORF">Sste5346_000922</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17754">
        <property type="entry name" value="MCM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008046">
        <property type="entry name" value="Mcm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056575">
        <property type="entry name" value="WH_MCM3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF46">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23191">
        <property type="entry name" value="WHD_MCM3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01659">
        <property type="entry name" value="MCMPROTEIN3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="301"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="682"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="692"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="732"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="759"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="775"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="793"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="814"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1903009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="931" mass="101872" checksum="66380C2DEA928A94" modified="2025-10-08" version="1">MDSILLRDNEARDRVRQAEEFLDPNDRNVRSYLPSILTMLQKNQRRLVVNIDHVRDTRPEMAEGLLMRPFDYTLAFNQALKNIVKAAPGVRPDQSDDDVPYYCAWAGSFGMHSCNPRTLSSQHLNQMVSIEGIVTRCSLIHPKIIKSVHHSAANDTFYYREYRDQTMTNGATTTSAYPQQDDDGNALVTEYGFSTYRDNQTISIQEMPERAPAGQLPRGVDVMLDDDLVDRVKPGDRVQIVGIFRTLGNRNTNHSSALFKTLLLANNVVLLSSKAGGGISTVDITDTDLRNINKIAKKKNLFELLSQSLAPSIFGHDHIKKAVLLMLLGGMEKNLENGTHLRGDINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVMADRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVVAAANPVFGQYDPHKDPHKNIALPDSLLSRFDLLFVVTDDIEDTRDRQISEHVLRMHRYRQPGTEEGAPVREQGQQALSVGMQSQANGGSQRPTDVFEKHNDMLHAGVNGTSGGRGRPPANKKKELLSIPFLKKYIHYAKTRVRPVLTQEASDRISDIYVALRNDEMEGNQRRTSPMTVRTLETIIRLATAHAKSRLSNRVEERDALAAEAILRFALFKEVVEDVSRRKKRKTRTIDEAENVESGSDDDDEDDEDDEDGDAADGTFRRAGAAASGTPNSSRATRTSTRARGGAAANGRRANGNVAEEEEEEADEVEGDIYTASPSRASRSTRSGAAGTQSTGSFASSLPSSRLRGTQATEEAEEEDEEDEEADELASGAAALSIAPGSSAAAAPAATLAPARMNTFRRLLGQLQSTDLFQDDAASVDDIITQVNEKIASMPASAGGPFSRADTILALEKMEKDNQIMYTGGNLVYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRV3</accession>
    <name>A0ABR3ZRV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydroxyproline-rich glyco protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="669" mass="72404" checksum="057B40FC93142EC9" modified="2025-10-08" version="1">MDDEPSEATAADSGKRAAVNGAVKTRVESNGSTDGMMTISSRGDVVLDVLFETSRETLRTTRKNAKAASKSYISAASSASASATGTSVLKPQLPMAFRVESAALKKNSRYFANLLGDTRFKEARTVEEGLAALALDDIKPADADISRLPRVHIDDDDEGSRTAGRELVFAELLRILHWDGTVAPVVFNTDSGDQADKATSPQSKSKTAAKPGATAAKGRLARTTPVSGKVAATRKGAAPTGKGVRSEPATQNNSAVPQTHPVLLPGSRWSAKTTPTLLELATLALQADRFACTDAVSAYVRALRLRFPQPIVRSARGEGGIGGGMGSGAGGLPSMANEEAIRQKIFVAWLLDQPLRFHAGTRELIHYGSKRWVAALSGEDDDEVDYANGNGNGNVNGTTNHHDQELPAWWDLPNGLESELQFRRACIINCIASIPRHFLGLYTSRNRRQCKMGYESSAACDSFQLGEIIKFFFHKDLLFLQDFSATVMTPKGRRQQPRLSPADYAAVDINHILATLKQCPAYQLDKHHVNCGLRTRILPILEYIQAMIGASAVALHRHDWTAVHHGKASWLAAAEAAGLLDGDGYGDDDDDSDLDGDGPDGNSDRTPTFGKPPSRSVTAAKTDQYTPQVFRFTRSVAGDQRLRFEGSMAADRMARQLFTARRWNWTPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY9</accession>
    <name>A0ABR3ZRY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21456">
        <property type="entry name" value="DLC-like_SpDlc1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="17999" checksum="BB90BB0263C3C709" modified="2025-10-08" version="1">MADAPSNAPIKPTRLKQITEDACQSAIGSAEFYEHEKTEGWNTTIINSILKSLINESATTAGGAPTYKFAVNSTIVQHLVPTSQLNKSRGTDTATGADDAAADASGAKAAATGTDGKPHVGRRGMHSAQAAYWNEKTDGMWTYKFDGGEGKGFDIIVMVLWIAYDSGNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS35</accession>
    <name>A0ABR3ZS35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_000878</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="264"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="431"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="476"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1902966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="611" mass="66019" checksum="4CFDF08B9C98AC2C" modified="2025-10-08" version="1">MGGHGGGGGGGHGGGSPFNPAQAAMFALRQKYNEKTATYFAAAICGLIAIFTFLHWTRKLVSRSHVVPAALSSPFVVVSRRLRNLLVRPAPGLNSSGHGILVAVYVTINLTLMLTNVDKSSLSPEASRFGWMLVTNLCFVVFLALKNTPLAYLTSYSYERLNCLHQIAGCTTFLLMVFHAASYTAFFFKIGKPEILRENAQIAGILAGFMFLIMVAAAIFLRRYAYEAFYVMHLTAFCVAIVCIGFHRPDIHTRIPVVLSLTAALFLTDRLIRVSRLLLNSTNNEATVYALPNGGTRILLAKKPHRAVPGKHVLMWIPRIRTFEMHPFTIIDTEAANGTTEFVVKSYNGFTRKLHAYATANPGAKLWAAAEGPYGTFPDPMEYDKIILIAGGSGASYTFETLTWFAGHLDTLRSHPNAPKVHVSLYVTRVPGSSSSDEEIGNTTGTRIGRPPTRNNAGGATAAGPTTLTRETTTSDLHHDSDKEIVEEKEHAVEKENVTQRNSEEIGSPSAAANVAADLEKATQAADAAADAAIREANGSESQPLRHSFSPGRPDAETVIRNAVSSTARSQRVLVAACGPPALMKTVRSATAKCITSDGPSVELHCEQFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSE1</accession>
    <name>A0ABR3ZSE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multiple RNA-binding domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRD1</name>
        <name evidence="5" type="ORF">Sste5346_000237</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12565">
        <property type="entry name" value="RRM1_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="27"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="394"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="581"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="710"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="817"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="915"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="915"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="942" mass="101156" checksum="8162CC16EC47CCE9" modified="2025-10-08" version="1">MASSFPTKEAPAAASSSPDDASVEESSRVFVKNLPPNITDDQLRKHFSGGGRHITDLKLIARRRIAFIGYRSADEAKAAVRYFNRSFIRMSKLSVEVAKPISDPSLPTAYKMQRLHDLHNPAAAEPVVPATAAPAEEDASSKKRKREDLDEKSNPKLREFLDVMNTQAKGLSSTADVTSSMGAGAYGVAGEVPVVPDAVLDAEESENEEEYQSISTKKAKTSKGEESTPVAAAAEPAVAEAGRPSRVAAITATSIEEEEAQPAQATPEVVMLAAQPKLDASATDDDWLRSRTNRLLDLMDPSELPAPQMVAVPVAALAAAPAAPALEAPADAKKDDEEMPDAYNDKDNENDDYENPIRRLAPAVVAAAAAAAAPTPAPAPAVPLTAEEQIRKTSRLFVRNLPYDATEAQIQKYFTAFGSVLEVQLPVTNSGVNKGYAMVLFASPEVALAAFHNADGKTFQGRILHVLPAKAKKTAGSAAELDEFALAKLPLKQQRILRKKADAATSSFSWNALFMTTDAVNSAMAERLGVSKSEMLDPTSSDEAVRQAVRQTSIIEETKDYFESNGVDLEAFKPNTKRGDTCILVKNFAHGTASQELRKMFEEYGPVVRVLMPPSGTLAIVQFAQAAHGRLAYSKLAYRRVNETVLMLEKCPDNLLSNSASDTLDTAAATAGQAGKNKLVASDLLDGGKAEEAAADATAEAEDESSKQTASLFVRNLNFTTTTEQLAELFSPLQGFVAARVKTKPDPKKPGQTLSMGYGFVEFCNKADAAGACTTMDGHILQGHTLTVKASHRGTQDAAAQQREADQAKKLAANRGGKLIIKNIPFEASRTDLRKLLGTYGQLKAVRMPKKFGNSTRGYAFAEFVTAREAAAAMTALRNTHLLGRRLVIEFAEAEAVDAEEEIAKMQKKVGSQMDSVAMQQLATSRSHRSKVTIGDEEEEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTA4</accession>
    <name>A0ABR3ZTA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_001147</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1902704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="104" mass="11254" checksum="154F4D03468BA094" modified="2025-10-08" version="1">MASGFGLNGGPGRCFPFWQEMLACYVVNSSGEDEAGKKKCAPLLEDYYECLHHKKEAARVRTLQAALRKAEAATPRDAAPNAGQIRNLGLLGKEEDTQKILGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTC3</accession>
    <name>A0ABR3ZTC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SWI/SNF and RSC complex subunit Ssr2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ssr2</name>
        <name evidence="9" type="ORF">Sste5346_000926</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02336">
        <property type="entry name" value="ZZ_RSC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041984">
        <property type="entry name" value="Rsc8/Ssr1/Ssr2_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF41">
        <property type="entry name" value="BRAHMA ASSOCIATED PROTEIN 155 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SWIRM" evidence="7">
        <location>
            <begin position="206"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="498"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="499"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="791"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="397"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="811" mass="84723" checksum="1A46308498871E9E" modified="2025-10-08" version="1">MDEDSVNFGSPANGTPASNPPAAAPPADEPSTSAPEDVQMGEGDAAETQDAPNTTEPVIKEDSATPAVAGLSDNALNAPEAPAAATSGAEDEEMGDAGNSGSADATSAAAPASGVAAEDTKIDVTAAGENGTPAAGSASGDGAAPTGEANGEANGAAATEGGAAAAAEGAAAGEDGASAGAANSTKSKETVENAAREHLITQTHAIILPSYSTWFDMNKIHAIERKALPEFFNSRNRSKTPHVYKDYRDFMINTYRLNPIEYLTVTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDYEQRPSHVGPPFTGHFKIIADTPRGLQPWQPAADPVVVGNKKHADTDARAAASVAPKSELNLEVGRNIYEANARGAKVAGGSAAPAAGKAEAKTNGEAANGSAAAGAGATTNGTQNGTPAPSSASAAGAEDLTKKPSVKVNCHLCGIDCTRIYYHNPQAEGNPRAQYDLCPSCYLEGRMAGNQTSAQYIRMENPTYSSILDRDAPWSDAELVRLLEGIERFDDDWGQVADHVGTRTREECVLQFLQLDIESKYLDSEVNESGPVGLSIMGGSGGRLPFNQADNPVMSVIGFLASLADPASTAAAANKSLDELKRGLQKKLEAGGEEESASGDKEKEKEVKGDDDAMDVDGQRSTDLTLTTKTTTTTTTTTTLSSAQQNIANLPLASIGARAGGLASHEEREMTRLVSAAVNVTLQKMELKLKYFNEMESILQAERRELERARQQLFLDRLSFKRRVREVQDNLKTAAATGGDQGLRLAQDALVDGQRLAFPAAPPAGGVQPLSATPGTARSLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTR3</accession>
    <name>A0ABR3ZTR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial cytochrome c oxidase assembly factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000119</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PET100 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018625">
        <property type="entry name" value="Pet100"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968:SF1">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09803">
        <property type="entry name" value="Pet100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10711" checksum="918A21B6FC4E88BC" modified="2025-10-08" version="1">MGGLNLEVFKFGMYVLFPIGIMYYFGTNLDDRFAVHDFWPKPENSNRIPTERDEIHAELQRLRARRLYQRDRRLAEEAARPQPPANEDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUF4</accession>
    <name>A0ABR3ZUF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="230"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="555" mass="58723" checksum="3F6043299ACBA210" modified="2025-10-08" version="1">MTKVEITGEPAEPESFYTQQPHLEQTQSHQSHQSLQSHQSHQSHQTQQSQQQTSSPSTPYYVPQVNDNGHTYDDEDSKNEGKTNNSNSATLNNNAAYYRSGLASRLSALGARAASPINMLANRMGSEGFLPETMFKECEKAARVLRGFAEPSLSRTSTNSPSSDSKGKQKAPARRSLIHIPASVLHRAVGLAIFTTGRVGIHVSGATGSGVLIARRADGSWSPPSGIQVHSVGAGFILGADIYDCVLVLNTREALEAFTSNTRLSLGSSLGVTAGPYGVGGGFGVAAGGSSPATKGDMTDGNVPPTTSGTPSRLMDRAVYSYIKSRGIYAGIKIDGTVVTSRQSANASFYGAPVTVQQILRGDVPPGLWQSSVQVLMDAIRVAETSPFQGQPPHMPPRPQQQAQYPQYTQQYPQQYPQQPGQAYPQQWYAPAQAPSASWGVPGPEQPSPQQPTAQREATPVVSPVTPAIVTLTSTPTMTAATPAARSKEQEAAEEAAASAGLPPPTYSMIGEPSSSSSARDIVSPMTTGTADDEAPPAYVDEHNVHPSDSKSELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZV43</accession>
    <name>A0ABR3ZV43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding ribosome biosynthesis protein mak21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MAK21</name>
        <name evidence="4" type="ORF">Sste5346_000059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040155">
        <property type="entry name" value="CEBPZ/Mak21-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048">
        <property type="entry name" value="CCAAT-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048:SF0">
        <property type="entry name" value="CCAAT_ENHANCER-BINDING PROTEIN ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="688"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="605"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="793"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="996"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1021"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1003"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1164" mass="128242" checksum="F72B3D10B9625FD4" modified="2025-10-08" version="1">MAPNKNKAPKGKAGNSNGNASSAAFSQASLTQLTAQIDRDLETRNAKNLNNGGKRKRSDGDDEETKTQKKQATTDSPKSKRKEKKEKAPKSDAAPATNGATDKVADKKTVMLDEIKLLGGDEEDLDLVAGIDSDAEEGGAKVGGGKSSAGADEDLSLDAAFQSELAKFAAGLGFDEVRLEDEDDEAAEEEVEEPAEEEVEEEEEEDDEEDVEEEDVEEENDEEEEEEEEEEEEEEEEQAPPLAVISAPKPTVSTDPFLPRNPKFSQLMLEPRAEWFTADVGDLPAPISDDIGRFSHTIQSLKDYADTLIETDSNAYRTITSASSSHRFMSTIMTSGTMSDKVSALTLEVQEAPIHNNKAFENLLALAGKRSRGAAIAALGALVDLLGNGVVLPSDRRLRSFHAQPALLGALQSASPATALAWKPHLPLPGGITKAHLMLWKYEDWLKDAFFRMLQQLEVWCNDEIEYSRSRSLDFVFGLLRSKPEQEANLLRLLVNKLGDRERKIASRASYLLLQLLTTHPGMKTIVVQTIEQEILLRPGQSLRAKYYGINTLNQTILSNKEPEIADSLVRVYFELFLTLLKSGALGAIDIPGTDNLGENAEAKKDAAAKDSKKKWKRSYNDKNKDTKKGSAADKNEGNEKDVSEKLVSALLTGVNRAIPFANTDNTTLEKHMDTLFRITHSSNFNTSIQALMLVQQVAGSKQIMVDRFYRTLYESLLDPRLVMSSKQGMYLNLLFRALKNDVDVRRVKAFVKRMLQIATLHQPPFICGVLFLVVELESTFPDLKALLNEPEFDDEDEEEYYRDVPEEGDEAAKKAEDTKKAEEEDKKKKRAVYDGRKRDPSYSNAQHSCLWELVPYFHHFHPSVTAFATNLLVRQKSLPKPDMANHTLMHFLDKFVYRNAKSVDASASKARGASIMQPVAASNGSMTGAAQIVAPSGISGASKQTVAINSAAFWGQKAENVAAEDIFFHTYFSQVGKQSQTSRAAKRAAKQEKAAAKAEAAAGEDGEDVSDAEEEEIWQALKGSRPDIEGEDEGADPDMDMDDDDDDDLEDLKDLLNMSDSDEGDLDDDEDDFDGEDAVGGADEMDVDGSDGGVEFADFADFSDEEGGKKDDVEADEDGLVSLVSKNGRKAGRERRKELKALPTFASADDYAEMLGQEEDEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZVG1</accession>
    <name>A0ABR3ZVG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peroxisomal-coenzyme A synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05926">
        <property type="entry name" value="FACL_fum10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045310">
        <property type="entry name" value="Pcs60-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="426"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="56242" checksum="AAC4FF6C1641C741" modified="2025-10-08" version="1">MAIPLTLRSAINGASSSTAVIIPASGPNGKALEVSYLDLVSEVSRYQAKLAALGIGRGAPVSIATVNSYEFIIAFLAASWQRAVAAPLNPAYKQEEFEFYIEDVKSAIVLVPKGAFAADAPAVRAARKFRAAIAESYWDAERGEVALDVKEFGGLESGPQPTLWPKPHDTALVLHTSGTTSRPKVVPLTHRNLTVTMKNIQDTYKLTAADRTMLVMPLFHVHGLLCGLLAPLYSGGSMIVPTKFSATDFWRDFVGHKANWYTAVPTIHQILLKHPIPNPRPNIRFVRSCSSPLSPTVFAQLEKALGAPVLEAYAMTEAAHQMTSNPLPPAKRKPGLVGLGQGVQVRILNDEGAELPQGKEGEICVKGDNVTAGYLNNPSANATAYTADGFFRTGDQGRKDEDGYIQITGRIKELINKGGEKISPIELDNVLTRHPDVADAVSFAIPDDLYGQDIGVAIVRKPNTSLQPGDLQAWVAEKLAKFKVPKKVYFTDVMPKTATGKIQRRIVAETMQKQDGKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGD3</accession>
    <name>A0ABR3YGD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Quinate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_010259</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000124">
        <property type="protein sequence ID" value="KAL1887379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF34">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="28"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="542" mass="59567" checksum="F7BBD7AAADF57809" modified="2025-10-08" version="1">MGMGHVSFAIAEDRPTPKEVYNWRITSCAIVASFSAFAIGYDSAFISTTLALPSFQREFNFASYSASGLTNLQANIVSIYQAGAFFGALAAYPLNYYVGRKKTLYAATIPFIIGASLNCAAHGPALGLMLGGRVLTGFGVGVCSSVAPMYLAELSPPAIRGRLVGTWEIGWQVGGIIGYWINYGVNENLASNHKQWLIAFAIQLVPVGMLFLGGIFIPESPRWLLTKNKREQATKSLCWLRNLEPTHTYILEEISDIDAEVERCPPSIIQPFRSFAKRSIQWRFALGSLLFVLQNCSGINAINYYGPIILKSIGITGTSTALLATGIFGVAKTLCVVVYALVIVDRVPRRTLLMWGAACCSVCMWIIGAYVKIADPSAHVMDSPTGGAIAAIFFFFLWVVPYELSWSSTPWLINAEMFPLDVRGLGQASAAASNWFWNFIVTRFTPRMVLSMKYGFFFFFASLLIVAIVFVYFLVPETSTIPLEAVDRLFSIHPVRKAHAIVLADVRREHAELRHQLEGDGEKVEQTGGAQHDEIAAQQDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGW1</accession>
    <name>A0ABR3YGW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MoaB/Mog domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056596">
        <property type="entry name" value="FLAD1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675:SF1">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24102">
        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="1">
        <location>
            <begin position="72"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="348" mass="38213" checksum="8304ECE462D35E62" modified="2025-10-08" version="1">MSQRLTHILRHVSAPTSPFLRASSSVSASSLSARSGFSAASASFTAARPTLSAMAELSTAARNNAKPIHTAACLIIGDEVLGGKTKDTNSTYVAKWCFSLGISLKRVEVIEDDESQIIEAVRRMSENYDFVVTSGGIGPTHDDITYPSIAKAFGLEVKLYDEAYRRMKEISIARPRPNQPVVDWDVDSPALRARLRMVELPTDPAIAPEKQFVFPREDLWVPVCVVNGNVHILPGVPRLFEMLLDNLTPLLLPRLEGRQIARVLISTPLPESVVAPYLTELAAKVEPQGVKVGSYPRWERKRNTVTLVGKDAALLESLVAEVVENVQGRRITVEGEDDESGDEKEKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH90</accession>
    <name>A0ABR3YH90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RRI1</name>
        <name evidence="12" type="ORF">Sste5346_010050</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="11">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="368" mass="40504" checksum="AA74CBC75B7736E5" modified="2025-10-08" version="1">MESSSQFWGEEGLTTKVDSVRDALYNYDADAQKVINDDRPWARDPNYFKLVRISAIALIKMVMHSRSGGSLEVMGLMQGYVDGTTLVVTDAFRLPVEGTETRVNAQDEANEYLVEYLKLCRDQGRMENVIGWYHSHPGYGCWLSGIDVSTQAMQQTFNDPFVAVVVDPDRTISAGKVEIGAFRTYPENYKAPDDGPGNSSAIASDGFQSVPLNKADDFGAHSSRYYSLEIEHFKSSLDAHLLDLLWNKYWVQTLSQSPLLTNRDYENKQILDLGQKIKEVTATIQRVGRSGGQSGSAGVGLAFGSGGMARKSVQQASERVERNSKTLAARERSGLMASDIKSRVFDTDPAGIASIQTDEETGTSHPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHU9</accession>
    <name>A0ABR3YHU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cutinase</fullName>
            <ecNumber evidence="2">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF1">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045364124" description="cutinase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="251" mass="24960" checksum="665143AF1A6DFAEC" modified="2025-10-08" version="1">MKSSILFSVLLSSGALAAPASQSDSLISGRQSNFLSLVEIFFPVGVSLDNSSEGAAMSTAGNALAKAAGITTTQGDVGTGACSDMTVIFARGTTEPGTVGTLAGPPFFDAIKAKLGGSATLAVQGVDYPADVPGFLAGGDKAGSQTMANDVTAALAACPDTKLVMAGYSQGGQLVHNAAKLLPAATMAKVNSAVIFGDPDNGQPITGLSAAQTKVICHAGDNICQHGDLILLPHLTYSQDANTAAAFVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHZ6</accession>
    <name>A0ABR3YHZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="494" mass="54196" checksum="B06C4D40693C2A2C" modified="2025-10-08" version="1">MANLDDIVPAGASTEDYLAIVNAWSPEERIAREKKLKRKIDFRLLPILIIMYIMNYIDRNALPQARIQGLEKDLGLKGVEYNVVLSLTFVGYILMQVPSNMLLSMLRPSWYLAACMIAWGIVSGSTGAVQNFGGLLACRFFLGIAEAPFFVGVAFLFSGWYTRKELGLRLGIFFCAAMLSGAFGGLFAAGIAAAFKHNKIASWRWLFIIEGAATVVFAAICAFVIPDWPTTTKWLTEEEKALGVVRLIEDAGQEEEDIGMKQGLRIAASDYRVWLCIVGQLCVQAVASLTNFLPTLVANFGFNTINTLLLTAPPYIATALFCLFNTWYSDRTSKRSPHMVYPSIAALVGIIITIATTKTAARYFALFLMLPGTYGCFQISNAWMANIASRPQKARAIALAMNNSIGNLALVWTPYLYPSSAGPRYTVAWGVNLGLTVVTIASSVVLSMALRRANKALDLAEANSVIEGGDLDTKAADSHVEVRATYDQKFRFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIK3</accession>
    <name>A0ABR3YIK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrodipicolinate synthetase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="34707" checksum="CF8CE07E89981402" modified="2025-10-08" version="1">MTTPGKPFPPGIHAPCLTWFDNDATQEIDWDLQTKHIEFIIGSGVHGIILAGTNGEAVALTTTEKEKLVRTTVEVAQRLNRPDVTITMGCGGQSTREVIAETRLAKEAGAEFALVLVPSYFHFAMNDAAIIAFFEELADVSPIPVVIYNFPTVAAGLDCNTDVLSKLGQHPNIVGVKLTCGGIAKVARIAAEFSPPQFSAVAGQSDWLVPALTVGGTGAVTGVGNLYPKSCVQMYDLYKSGNVKEAEAAQLRLAQMEWGFAKGGINGTKWAVGKFLGYAAEKRHCRRPYPQFADESKQAWISTVVETLLADEKKLNRSPLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIK6</accession>
    <name>A0ABR3YIK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mgpp2cl-1, protein phosphatase 2C-like protein 1</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MgPP2CL-1</name>
        <name evidence="8" type="ORF">Sste5346_010037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="167"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="570"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="653" mass="67872" checksum="C95F6540ADFF5027" modified="2025-10-08" version="1">MFGGGSSASLKAESAIDDSSSGGDGATLAPAAAAAGSVRKNSNKSPSPEPDSAKTSPATPIATAEKSAKSSSPERKAGNSSSPPTSGSSAEPKKRRSSGVSSRASSLLASAKNTLNFSQSGRSSSDASSNQTPLEKLGKQDAALAVPQGQHNNSAGESLPGPRSTFRVGVWEDRNKKCRRTMEDTHAFLYNFLRTPAPASNVTDKDSTKSFKSSSDSSAQDAAVSSAGNSGIDLVSDSLETDNGYFAIFDGHAGTFAADWCGKKLHLILEEVIRKNPNAPIPELLDQTFTSVDAQLEKLPLKNSGCTAAVAVLRWEDRVPSNQSATGSQGIAMAAAAKASDDAAPKADEKKGSASASTASTRTTADVETAHAKLKPNALRQRVLYTANVGDARIILCRSGKALRLSYDHKGSDENEGRRIANAGGLVLNNRVNGVLAVTRALGDTYIKELVTGHPYTTETVIQPELDEFVIIACDGLWDVCNDQDAVNLIRNVADPVAAAKMLVDHALANFSTDNLSCMVVRFDKEALVETHNSNDGLIGVEGDEAGSSAKPSEADKIVNDIKQKIAQGGTPAIGVSASNSGRGHDSVPIPPNDEAFKPTAIEGSVEEEPVAASDEPVQTTPEGSTLSNNTESSAATTDDQHLAPAKPSEVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIP4</accession>
    <name>A0ABR3YIP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ESCRT-III subunit protein did4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DID4</name>
        <name evidence="3" type="ORF">Sste5346_010038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="25596" checksum="9F64191218287404" modified="2025-10-08" version="1">MNMLEWAFGKRITPAERLRKNQRMLDKAIRELDQQRVKLEKQEKALIAQIKQSAQKGQMGACKIQAKDLVRTRRYVEKFYGMRSQLQKISLRLQTYRTNEQMMQAMKGATMALGSMNRTMNLPSLQRIAMEFERENDIMEQRQEMMDDAIDDAMDVGVEEEGDEVVEQVLEEIGVDLTQALGDTPQGLQSATVPEGKIAQAVGGGGGGGGGGGGSAGDDDLQARLDSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ78</accession>
    <name>A0ABR3YJ78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="237" mass="25104" checksum="064254DA62CD39AE" modified="2025-10-08" version="1">MAWRSSGESLAELVGNLCANRMITDDRVKQAFLSVDRAHYATRSPYKDAPQSIGHGVTISAPHMHALAVQHLMPYVVPDAAEGRGGPRILDIGSGSGYLTHLLAELAGPQGEVVGVEHISELCETGRANMAKSEGGRAHLESGQVKFVVGDGRKGAPSPLADGGFDAIHVGASAAKLHTELLDQLRSPGRIFIPMDDEGDHGAGNQSVWTIDKAADGTVTKKRLFGVRYVPLTDAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJM8</accession>
    <name>A0ABR3YJM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="567"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="836" mass="92790" checksum="902F2CDF193AA0E1" modified="2025-10-08" version="1">MHLMSKEDMKETAWRWRCKVLRTSDERNLSDYDSASSYDSDSDRNKEDGDSNGGVIQVHQVGPGFVGNLVDSLRTQKKGSKASAQAAKDANVLGSSLTVKTLYEGPNVGDNFHNWQDYPPRQLSKSATKVQDRVAIKLYKIKDKSRPVIDGRFSMKFHQIDIQNPLIVQALAPILRDREDYHLDPEETATFNAPFRPLYFCYDAIVDKLKSLKPQTEPADAALHPFLKLLVCVLDDLFAEVRQKRKALLERGLMSYEHAWTYFPRNAIVRSHGPNCDVLSKVLDTAYVKAMATDSLVIRTQVLRFNGEAFVWQKQELKINSYGGNRPITEFDHCPLEHLPADEQTHLKTRLAERGRLVLDCQGLAYRQYTGVGMLLNEQNKMEKHNVDGRVLIDVIGYNKHHLAQGVREGKDPQSAKNVVEGTGRKPRTAREIAMGHRARVAAAAQAQAQASGTAGNGNDADAKLLLTTSTGKIQRLTEEEQAANKAKMLEKPEELMFMSPMVEGYALKNKLWFSFFVEDIRPIKWNDQAYDHLVYDDQQKDLVLSFVESHGHTTHKVDDVIIGKGDGLIILLSGPPGTGKTLTAEAVADRTHRPLFYLQAEDLGINAAALGANVKKVFEMATEWDAVILLDEADVFMAERHPQDIARNELVSIFLRELEYFRGIIFLTTNLYDTIDSAFRSRVSLHLLFRPLSAEARLSVWRKFLARVDGHTKAVEAIEGGAVEDGDGGADDNGGEGSSGAGSLQIVEAGEAGEAGEAGAGEGGPAVAEPITEEELEELAAWNLNGREIKTAVKMVTTWCAHKGHAMTLERLENGIRVTSPHSTKTTQASSDLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJX8</accession>
    <name>A0ABR3YJX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4 15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Sste5346_009615</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the NSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4 15"/>
    <dbReference type="EMBL" id="JAWCUI010000094">
        <property type="protein sequence ID" value="KAL1888335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Non-structural maintenance of chromosomes element 1 RING C4HC3-type" evidence="17">
        <location>
            <begin position="327"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="405"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1888335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="467" mass="51065" checksum="D491C94475402E8B" modified="2025-10-08" version="1">MPQSSRKRARSDAEGGRSDRRRSRRDDDANNDHDDSRADDSMAGPSNGGGMDVDNHAQSQNGQPSSWQLPAGYDDSNRAFLQAFMAHGALTFQQAQQVLAPILNVKNGLAATAAGASQEDFQFMSADEVTFAMLRQYINQAKSALMPLDFDIRSATNERAVSDGGGYNSNDHRVWVLVSTDNDPKSHLAVLFTPRKLAFIYRLLDALFDTYNTPRIEALCLTEQQALKLSRPPRTTARQSVGADAEGAGAGAAGADAANRDKGLKHSVVLSLLASLVRQGWLSKSAQGFYALTTRALLELEPFLVDQYNEEPAGTTTATSWQRIKYCAACRELITSGLRCATPTCTLRLHDHCEEAFWRTQARGSNTRHRCPKCEAPWGKAEEANGEVTGKLHFIGERAITSTDVYRRKKRQGRPSEGVDELMRTLQPRSATGGRGRGGGGGEGELAEPFRQAASRRREVEADGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJY0</accession>
    <name>A0ABR3YJY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="485" mass="58534" checksum="D038CB99109F1B3A" modified="2025-10-08" version="1">MSRYRDYDDEDEIDVRVYHRNKQSPPPPRVVARPPPPQVRGYYATGPAFLATERTVATRPRSRSRERRSSPPPVIINNYNTQHSDDDSDSGHHSSHHGHGQMVPRRQGRSHSRAPSSDYMSREEYELEKARRELHELKLRQAAANEELELHVRHNDREEWELQQARREIAAFRAEEHDRERKIRQQEEADMARAKRELDVIKANQDKERTERLREKEYKSQAELERAKRELEEIRRREDRELEEKRIKKDLELKALEAQKKAQDEKDKRDRMEKEAIERYKVKEAERIAKEKAEREENEREYKRRLQEDLLRSGVDEKDIKAILDKKSVKPEKKDEKKPQRTDINIEIGGPAPVPQRPTYTRMARRHLSIETLNYYHVDFDYDQVRSTERAVYQPEYENKQILIHYMQDPDYILVKRWVPEDERQYWWQHTKTIRENRKVVLKIEDGTKHHHHHLEPEFEWVRKKERRRSRSKSPGLLMYLAGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKF1</accession>
    <name>A0ABR3YKF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049791" description="Cell wall protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="16435" checksum="58CE9DB8B4D6791C" modified="2025-10-08" version="1">MFAKIVLVAAVAAIAEARFGQEGAIQATIQGLSSFGNPGQAATLAGQTPGVLLAGANACAKLSLADQIVTALGNDAAVLAAAAQLVGAEKNFNPSAQSIPTLCSDATLPATAALRGIVPLVDPSVTGAEVENANAATSLQTPFSATGLSVADVAKAQGFTNFTAQANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL87</accession>
    <name>A0ABR3YL87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPR repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044244">
        <property type="entry name" value="TTC27/Emw1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="672"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="706"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="767"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1054" mass="115740" checksum="12385F82393B8F0F" modified="2025-10-08" version="1">MSTNMELEALLRRGRYGQVLTHSDAHATVEAFVKDILSGSQIQSQTATSDQEDSRQAALAVSLAAFNAFLQVNVTGPVLESSQQVQELLAQLEQPESASSSLRRACLKSLDIDGVSVYPYIPHIELFCLARWVFLSYFANGNYSPLASPDAQAKTDTDPAENSLSWLQLRIHVWHYKLLTEPNPGPGSVFNKMTQWSDLPTLQEQIQKCLDETEQQINATDAAWSQQNRVQFLVEKTNIYAMLGLDIKAQAALDAASALDHFEYVLSGALGKRTRFQEKSTSQLVILAKSATDLKSTASESTGPVPGAEETAAISVPQALPLNNDTLLESIDFTDARKMTTENAVQDAANSQEQAASSSSDAIPASLRDISPDDQPQLSPLDQIILLSVATLKDAFSPADALTLEEILPYATRVLADKSTNWQIYSQALIVRSRIELHRSRTVERGVLQMQAMVDQVVVDTTAPEVTELQSGVVTDVTDEDESSVPAIEVTAPGEHEKQVDKAVDQPTSFFPAAKPSEQAPPQVRLRYIHALATPPKWHLEAELAFAWAGVGSLISALEIFKRLRLWAEVALCLASSSATDDETGRNSGGEEKARGLLRWQLFQASDPSLEPESGEDGAELNVMSLKGSDFEGPERDSPPANAPRLFCILGEIENEPKHYDRAWDLSKGRYSRAQRSLGEHYLQQQEWEKALDAYKKAVLANRLNSQYWSRLGDINLRLGLFSEAAEAFSRAIGAASDAAGGEDARTWSNLGSALYSLYTQTMKERREEARRKKESAENDEEAPTTQVAGLDEDEEGDEEPGAVEKVSVTAKRDPARLLTQSLAAFKRGATISHDNWRIWDNVVTLASRVRPPVVSDITLAMRNILAVRNTEDAIDIDVVRLLLNESVLVKPKPTDGVPARGSQEKAVCDLVENIFVPLITKRSELWELVARERVWRGDYAGAIDAAEKGWRAAVGGANTGALGSTMAVSKPGEASEDEKRNWLENADAWDNVVERTDELVSILENYGPEAATIGSRWKMKARSALRSVMGKGKERWEGSAGWMTLENLLEGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLH9</accession>
    <name>A0ABR3YLH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="600"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="657"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="806" mass="87061" checksum="8230F92911DD5A50" modified="2025-10-08" version="1">MAGSSNSHTPSGGSGLCPSFSIDAVSSASRDGLGPPRAGSPQPSPRTRPATHFSNGGSSFDVDEDLHLSEAGPSDAPTETTALLQDVLSDRHCSHSGSCNHGTFSPRPTSPAPTDGSSDTGVDSAGDGPSASIPIIDGLISTITGSRDSSTWRRSLARKVRSKKMSTSSVLAERHGLTDTGSMYLAYYVPSVAWMSQYKLSYLKGDCVAALTIAGIYLPMALSLASNLSHVPAISGLYSFVFNPMIYALLGSCPQMVVGPEAAGSLLVGTVIRSSVDSGRGDEDDDVLHAQICGVVTGIAGATVLLAGIARLGFLDSVLSRPFLRGFISAIGFVIFVDQLVPELGLSKLASETASVDHGSTVDKLRFVFSNLDKVHKLTAIIAFVSFAVIMVFREIKRRMQPRYPGVAYIPDRLFVVILSAYLAWRLGWDRQGVEILGTVKAASGHTFTFRWPFQASHMNHIRDSMSTSFLIALLGFFESSVAAKSLGGQETFPGIQLSPNRELVALGVANFVGGCFMSLPAFGGYGRSKVNKQTGGKTPMSSVFLSLIALVSILFLLPYFYYLPKPVLCSMISVVAWSLIEEAPSDISFFLRIHAWPEIGLMLIIVLATIFYSLNLGIAIGIGLSLLQVIRHATRPRIQILGRIPGTQRFENAEDHPERLEFIEGCLIVKIPEPLTFANTGELKTRLRRLELYGTNKAHPALPRLRREEHNRNVVFDIHGVTSMDGSGTQVLEEIVRSYRDRGVRVFFSRGPDKAHEVWQQMQLSGIVDLIGGEAHYVDDVQEALKMTEVEEGSELGVRAPPLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMT8</accession>
    <name>A0ABR3YMT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008881</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="393" mass="41879" checksum="46BBA42ACF1CE0B5" modified="2025-10-08" version="1">MGRTFAFSHFEVMGCAAIMKQHADIALHIQGQSSLNTPGMITFTLKQPFGVVAGILPWNVSLIMFAMKTAPALATGNCVIIKSSEKSPLGALKVAALFKAAGFPPGVLSVVTGTGPTTGSLVASHMKIRKISFTGSITTGKKIMAAAANSNLKNVTLELGGKSPAIIFGDADIQKAALAVEMSIHLNSGQHCQANSRVFVHESIAEEFSKALVALMTNRSIGDPSDKSVFQGPQGDKLQKERIVSILEQGKNDGTVLCGGKEADVNGKGYFIEPTIIKDVADTSILATEEIFGPVIILNTFKTDQEVLQRANNTEFGLYSSIYTKDVERALKFARLLEAGAVGLNCSAPTQALDMPVSGWKQSGIGSEMHMYGVENYLQTKAVYMKYADVAMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPC9</accession>
    <name>A0ABR3YPC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008367</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="3"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="36566" checksum="B38F70EDEC5EFC60" modified="2025-10-08" version="1">MATTMKAVQWDPIQQKVVVNTVPKPTPGPGEFLIKLASASLCHSDLMSIAIPDRKEPVTLGHEGAGYIEAIGSTAEGKGFKVGDAVGFLYVQGGCFECKGCLIHNNHCVRSPGQTNGFTIPGFFAEYNTVDWQNCIVLPPAIDVKTASPIFCAGITSFHCVDSCELKPNDWIVIIGCGGLGQLAIQYAKAMGARVIGLDINDNTLANAKAQGADYVFNSRTNAGYKDEIVKITEGGAQSVAVFSAAEAAYDSAVPLVEVGGIIMVVGLPNNGVRFNALDIVTGRYRVKGDSTATPQRMPKAIDFIVKHNIKAEMELHDSLDAVPEMIERMKAGKSTKKMVVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPE7</accession>
    <name>A0ABR3YPE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_008410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="102"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="634" mass="68697" checksum="53B5B0C0CBDA824C" modified="2025-10-08" version="1">MPPTKTDSRPSLDEDDAFALASDVDTDSDAGNDVANRRINTTDKDDFNDFDDDAVPSERQGLVDRQEPSLVANDTAEASSISREPDLTIHQAVRVYRKAILWCLVTSACVIMEGYDMILIGNFFAYPTFAAKYGQFVDDNGQHQLSAAWMAALANAAPVGCFFGTAANGYLVSRYGQKRVLLAALAALSAFIFMTFFAPTIAVLLIGEFLCGLPWGIFASSAPAYASELLPTALRSYLTSWTNMCFILGQLIAAGVLAALVDRRTDEWAFRIPFALQWLWPVVIFPVLCFAPESPWHLVRTGRRSAARKALGRLQTASAPGADIDATLATIERTNAMEVEELKGDVTTGTSAGADGSSETTTYWDCLRGTERRRTEIACMAFAAQVLAGAPFAYNSTYFFQQVGLATHTTYLLNTGGTLLALAGTVVNWIVLMPRYGRRTIFLGGMATMALLLTVVGALGFVAQGDKTPRGVGLVQAALTLAWTFVFQLSVGQLGWALPAEVGSTRLRQKTVCLARNAYYAASIAANIAQPYLLNPGALNLKGTVGIVWAVLAFGVWLWAVFRLPETKGRSYAALDWLFAQRTPTRQFATAKVPKEVVGGGDTTHPEVNTAGYSFVHADDTTDNHEMERLVRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPM1</accession>
    <name>A0ABR3YPM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5 16">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DGA1</name>
        <name evidence="18" type="ORF">Sste5346_008405</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Endoplasmic reticulum membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5 16"/>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003846">
        <property type="term" value="F:2-acylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16 18" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1890251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="432" mass="48826" checksum="2395E9970B49D6B0" modified="2025-10-08" version="1">MPSASLDHELPNNNNSGNRVNGTDGVRQRNHKTNDHADHDHDHTDTEKPSENMESNNQQPRQRTVNGTTNSTSPSSPSASGSTTQQQQEQPKGIRFAPLRVPLRRRKQTLAVLVHCSCLMMSIPLFFFCCAVPLMWPLIIPYFLMIVVSSASTNGRLRWRSERFRSLPIWTWFANYFPAQLHKTADLPADRKYIFGYHPHGIISHGAWVAFGTNALGFREKYPGITNSLLTLDSNFNIPFYREYLLMAGMCSVARESIINILSSGGPDKKGQGRAVTIVIGGARESLQANPGTMRLVLHGRAGFIKVAMATGADLVPVLGFGEVDLYTQLQGGEHPLLHRFQMHVLKVWKFTLPFMRGRGIFNYDYGLMPYRHPLNIVVGRPIPVQKATSETLDPAEVDRLHELYCEELRRLWDTYKDEYAPDRVEEMQILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ32</accession>
    <name>A0ABR3YQ32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039249">
        <property type="entry name" value="GPATCH11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21032">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21032:SF0">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="102"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="399" mass="45716" checksum="991B11D1E2997772" modified="2025-10-08" version="1">MADDEEDDYMTMTFVEEETGASKKNNKKKHVAETSLQRRIRLEREGRERGRVPSKAELAKTAEAEREAALSRSLFDGPKKAAAITAATSKWPSPPTAPAPKPVSKGFAMMAKMGFVAGQSLGKKRGGNEEGKEDGQDRKDDRPITEPIRIQVKRDRAGIGAEEEKREREREKSEKEGDGDGPETKRLRLDDMDPMEYRDRLRQEREAGRLERQIHAAQVVAERMARGDEEEDDSQHKDDMPLSEVNVLWRGLVKERRTKEHEREQRIKAQRLLDDRLRSIVHGDKEKSNYTAFEQDGSDDDDDKNDLVAHGKADKLSYLKGGMNKSIPVDGEDDDEDEDATKEVEDAQLDEFNALEPQERLQQVVDWMRQNRRYCFWCKFKYPDDDLEGCPGPTEEDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQB8</accession>
    <name>A0ABR3YQB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="5">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">IDH1</name>
        <name evidence="13" type="ORF">Sste5346_008183</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="12">
        <location>
            <begin position="46"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="382" mass="41500" checksum="BCA298196AEB8159" modified="2025-10-08" version="1">MMSQRSARAAQSLFKAAATPAPAAARSFATVQSDIFKPTKYGGKYTVTLIPGDGIGAEVAESVKTIFKADNVPIEWEQIEVTGVDTATPTGRTEDLFKESVASLRRNKLGLKGILHTPISRSGHQSFNVAMRQELDIYASISLIKNIPGYKTRHENVDLCIIRENTEGEYSGLEHQSVPGVVESLKIITRAKSERIAKFAFSFALANNRNKVTCIHKANIMKLADGLFRSTFHETAKEFPTLEANDMIVDNASMQCVSRPQQFDVLVMPNLYGGILSNIGAALVGGPGIVPGCNMGRDVAVFEPGCRHVGLDIKGKDQANPTALILSGSMLLRHLGLDDHANRISKSIYAVIAEGKVRTRDMGGVATTHEFTKAILDKMEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRY4</accession>
    <name>A0ABR3YRY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="220" mass="25280" checksum="DE0F0827C63DD07B" modified="2025-10-08" version="1">MSLTMRAGTVDDIDRLVEIYFSAFADNAVQHRVFPESSPQVRPFWRNNFVNDFKEDYVRFRVMEQPSSGDSEGKKEIVAFAIWNAPRKPTDPIPAMPPREAWPSDGDQDAAVEFFHDLERQHKSYMAHPINPGEQQPHWYLELIATHRDHQGKGAAGALLRWGEQQADEQGVPCYLDATPDGRPVYTSKGHGFREVESRTYFGGVYEHVFMIRDPKKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRZ4</accession>
    <name>A0ABR3YRZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008038</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="39"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="517" mass="56429" checksum="4EEFB17A723A8320" modified="2025-10-08" version="1">MAKIDAEAAQADADRLAAVLADDGTPWYQRSYLVKLNYCVVSLVLYSAGNGYDGSLQNGLQVLTRWNDFMDHPAGAWLGWINAIYWLGCFLGYLLAAWISNKYGRKPGIYIGYLPLAIGVAMQTAAPNDKVFLVSRLFLGCTSALFGNGAPLLINEIAHPAHRAIANATFMSGWYVGGSIAAWATFATRNYSTSWAWRLPCILQLLLPVVALPGLLLSPESPRWMVSVDKCEAAREMLVQHHAGGDADSPLVAFEYGEIIAALAADKAAHKSSTYMDMLRTPGNRRRLFISISLGIFAQWAGNGVISYYLTLVLDTVGVTSVTDQTMISAFLQVWNLICAVGAAFVVDRLGRRTLFLASGCIMLVSYVIVTALSAEFAKSGHAAVGTAVIPFLFVFFAGYDIALTPFLTAYPCEIWPFALRARGLTVTWVASISAIFFNTFVNPIALASIAWKYYLVFVVVLAVMIVTVYFYYPETRRRTLEEIAVIFDGESAALPPMTKEGGDATLTVEHADEKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSD7</accession>
    <name>A0ABR3YSD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">P24 complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">EMP24</name>
        <name evidence="11" type="ORF">Sste5346_007723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045871046" evidence="9">
        <location>
            <begin position="22"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="203" mass="23161" checksum="E8736A4123906523" modified="2025-10-08" version="1">MVRLLFGLLAAGAALVQTVAAHNIQLPAHGRECFFEELHKDDKMTVTYQVGDREFGGAGNLDIDFWITNPPGQYETLQKSTSNGDFTFTAHHDGKYMYCFSNEHWGASSKEVSFNVHGIVYVSEADGPKDPLEAEAQKLSEMLAQVKDEQSYIVVRERTHRNTAESTNARVKWWNLFVITVVVGESIFQVWWLRRFFEVKRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSN0</accession>
    <name>A0ABR3YSN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-dependent oxidoreductase 2 FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="KsdD_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009472">
        <property type="entry name" value="PRK12834.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="3-KETOSTEROID-DELTA-1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260:SF1">
        <property type="entry name" value="KSDD-LIKE STEROID DEHYDROGENASE RV0785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036654">
        <property type="entry name" value="UCP036654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="3">
        <location>
            <begin position="11"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="577" mass="62968" checksum="EB1E0923DB973794" modified="2025-10-08" version="1">MPDKSESPPAIIVGHGLAGLVAAYELTQRGVNVVIVDQETRANLGGQAFFSLGGLFCVDSKAQRARGIKDSRALALRDWLGTAKFDRLDTQDRWPRQWAEAFVNFATDEFEQYVTKLGLSFIQVGWAERGDGAADGHGNSVPRFHLTWGTGPEVVRIFKEPVLAAEKRGLVKFMHRHMVDRLITENDDPNGRVVGIAGRVLKDDDEVPRGKPTTREAVDTFEIRGASVLVASGGIGGNVEAVKKAWPLDRLGPKVPKTFVVGVPAHVDGRMMGIAESAGANMVNQDRMWHYTEGIQNWDPIWPDHGIRVLPAPSSLWLDATGKRLPAFLFPGSDTLATLKHICSTGYDYSWFILDKAIVAREFALSGSEQNPDITNKSYWQTLLQRVLTKSGTVAVQKFCEHGVDFVIRDNLTDLVVGMNELAAEVGGPKLDLADIQETVEARDAQMDNPYSKDAQAMLIHNSRLFWYDKVSRVAPPHRIQDPKYGPLIAVRMHLLTRKTLGGIETDLGSRVQRADGSTFPGLYAAGEAAGFGGGGVHGYAALEGTFLGGCIFSGRAAGRAMADEIQGVKTPQESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSV6</accession>
    <name>A0ABR3YSV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytoskeleton-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48947" checksum="946BA3A35E9BE352" modified="2025-10-08" version="1">MAWYSFIRDERLIGIGIMAAASVGIFVGVRAAMQPYHNSSVVYPLMPKTQYITQDTEDSLSADTLNSLLDHYNFSIRETAAKIVCDRAINDDATVGRLLWGMGRPAYDERMMSLRALSMLTDQTTMHRLNNKEAFGAFVKCLEQCMATNLKEGSGVDGISTEGTLIDDVYFDDYYLRDYSEKLCLMFLAQLTDKYDIDLLVRVGFVDRWLAKQRWGSTPGARIDNFASFVRHRDNRVADICRRLKETPLGRSALRKAGLLDPTPTPRRGQRSHHHKQLELLQLQMPPSPLDAPLRLEQRSSSTLTNGNSDAASAQPRGMEAVEDLTTAYTRDIAAGGDGSNIPVRTLLNAMEATGQLDYAQELIDAAVREDTAERENTTDTATTDNDGDSTRQPRPPSQSSREEQRIRRQHREAMVLNDGTRPLRRDDIFERESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT26</accession>
    <name>A0ABR3YT26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_007592</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="296" mass="31456" checksum="076AE5327AB5B84A" modified="2025-10-08" version="1">MDPYSAEGELINIHNHFHQGQFQDVADYPTDSLSPENLLAARVLQLRARVNLGEAKKVLADVKGASEPALQAVGALAEQRAGRSDAAVATITKLAETAGDDATVQIVGGTVFQAAGQSEEALALLSQHDSNLDAVALIVQIHLQQNRNDLALKEVVAARRWAQDSLLVNLAESWVGLRLGGERYQQAFYVFEELAQAPASSSARTLVAQAVSELHLGRTEEAEAVLEQAIKADPESADAIANLLVLSVLTGKDTTEAAAQLQSVDAQHALLTDLEDKSSLFDKAASKYQAKVASSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT40</accession>
    <name>A0ABR3YT40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DRAP deaminase</fullName>
            <ecNumber evidence="3">5.4.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RIB2</name>
        <name evidence="3" type="ORF">Sste5346_007686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.28" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160151">
        <property type="term" value="F:tRNA pseudouridine(32) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02557">
        <property type="entry name" value="PseudoU_synth_ScRIB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="217"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="587" mass="64027" checksum="A8DB32F7F751A1CE" modified="2025-10-08" version="1">MADAQQIGSAPAAAPASVEAVTVQEVISQTPEASIASTTQPTETKTAPVEQLQPVSDDIPEAKAKAAKLDSSHDAATAAHNGSSSIAEPEKAADPSAAELKVAHPDAAKDDPGANWPERYYLESGLRRVKPYYYTYNTWVKERWRGRTLLDVFESEFRDRPLAYYRRAMESGTVKVSEKIVGPDHVLKNGERVSHTLHRHEPPVTADPVQIIHEDDDMLVINKPAGVPVHPAGRYQYNSVVEILKHERGPGFIPYPCNRLDRLTSGIMFLAKSPTTAKRLSLQIQARVVRKEYLARVVGRFPDGEVICDQPILQISPKLGLNRVRANGRSARTVFKRLAYYRPDGEKDVPPSEGPESRKGYSIVRCLPVTGRTHQLRVHLQYLGHPIENDPIYANQKVWGFDLGQGDADATVHTDEDVISRLSRMGKEDVAEAVAYYDEMVDEYHKRKAERMSGQVCDECDTPLYTDPGAHELSLWLHSLRYEAADGAWSYVSPLPGWALPPAGYTGPTEVGGLDDLVGAADAPGFEAEPDTKTDDAVSKKDMKAMEAAPAATATTAATTEAPAPVPTPVPEVPALAVDTPAQASAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTB4</accession>
    <name>A0ABR3YTB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12 13">Homoserine dehydrogenase</fullName>
            <shortName evidence="12">HDH</shortName>
            <ecNumber evidence="5 12 13">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HOM6</name>
        <name evidence="17" type="ORF">Sste5346_007539</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:15763"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12 14">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5 12 13"/>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_Aspkin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070:SF5">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12 13" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 12 13" id="KW-0521">NADP</keyword>
    <keyword evidence="9 12 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Aspartate/homoserine dehydrogenase NAD-binding" evidence="16">
        <location>
            <begin position="13"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="155"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1891623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="368" mass="38869" checksum="B819EBED8BE73E39" modified="2025-10-08" version="1">MATQHRVFIAIIGAGGVGKCFLGQLADLAARRPATRLSLCYITTSKKAVYNKDYSDISITGAVDSLASSSQTPLSIPALADYLAGAPAKVILVDNTSSQDVADTYPLILSRGISIVTPNKKAFAGSYKHWQDIFTSAASSGAKVYHEASCGAGLPLISTVKDLVETGDQITKIEGIFSGTLSFLFNSFAPANPSGAVAGKWSAEVSKAKELGYTEPDPRDDLNGMDVARKLTILARLAGLPVESPTAFPVESLIPKELESAASGDEYLEKLPQFDSQMEELKAAAEKEGKVLRYVGSVDVTTQTLKVGLQSFDRSHPFAALKGSDNIFSFYTKRYGSNPLIIQGAGAGGEVTAMGVTSDLIKVLSQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTL6</accession>
    <name>A0ABR3YTL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Auxin Efflux Carrier superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF2">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="64434" checksum="5BF57D2EDD7FF21B" modified="2025-10-08" version="1">MESLSSGCITEMQAINMMKSHESHPSFSRLVMLVFEAVMEVVCVSLPGYIIARLGHFDADKQKFLANLNVMLFTPCLIFTKLAAQLDANKFVELGIIPVIFVVMTVVSYIVSKVVTRLFGFNRRAANFVTAMGVFGNSNSLPISLVLSLSQTLKGLHWDRIPGDNDDEVGARGILYLMIFQQLGQVVRWSWGYHVLLAPKSKYEEYNQDTAEEGRYRDDPDSDETAEDGSNTVIVGVTAGSDDNEDENDEDEDLMVHSPVTDYSDVFVPSGRTPVAPRSRGSPYASDDENDNGSGSGSQGKRTPKKRSSKQHIHTDGNDFSGLAAANGAAEFDGRILSFPRIRNINEPDIPEGVEGVKVRLAIYRARGVNWIVATGSRTYAALPTPMQTVVDAIQKVASRFSHFLWEFMNPPLWAMLISVIVASFPELKRIFFEEGTFLNNSVTSAVTQTAGVAVPLILVVLGANLARNTQTQESHDPEEAQIGKRLLIASLLCRMVLPTLIMAPILALFAKYVPVSILDDPIFVIVCFLLTGAPSALQLAQICQINNVFERTMSKILFQSYVIWILPSTLVLVVCALEVVEWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTT9</accession>
    <name>A0ABR3YTT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Negative regulator of mitotic exit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KEL2</name>
        <name evidence="3" type="ORF">Sste5346_007471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244:SF456">
        <property type="entry name" value="MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1161"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1385"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1495"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="855"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1063"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1239"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1300"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="558"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="598"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="628"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1177"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1411"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1500"/>
            <end position="1510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1545" mass="166228" checksum="57900A982ECF293D" modified="2025-10-08" version="1">MAFLFKSKKNQEREKDRVLSSRDGPPTTNSQQSSITSNTTSRLARDEKASMQRSTPTGSLNSLDNDGTTSPDQAGYGRRAEQVTSQQSGDIQYRNGPGPTLGNSNMSLYPWSQRRLTYTTSTTSPFPRYGAAVNATGSKEGDIYVMGGLINSQNVKGDLWMIEAGGNMSCYELSTTAEGPSPRVGHASLLVGNAFIVYGGDTKIDENDVLDETLYLLNTSTRQWSRALPSGPRPSGRYGHSLNILGSKIYIFGGQVEGYFMNDLAAFDLNQLQMPNNRWEMLIPNSDNGGPPQGKVPPARTNHSVVSYNDKMYLFGGTNGFQWFNDVWCYDPATNSWAQQDCIGYIPVEREGHAAALVDDVMYIFGGRTEDGADLGDLAAFRITSRRWYTFQNMGPSPSPRSGHSMTSVGKSIVVLGGEPSSATTTVNDLALVYMLDTNKIRYPNDAQIAAGQKNAAQQGARRPSDAARQIASRDGSQGPRDDRKRAMGPGAVNSPTNGFRSPNGSDGNAPSPVNGGSRLPRAAGPSPPAGPPPQGQPPKPNQAARARNASSDRGGEYSSSPVLNNAASQGQSPVTRDPPKEIDSPAALGSGARQGPGPGPTPQLGPRGPPPRSDPPATPSAPPPSTAPGASEAAATVVAAAASAAAAAAVANGPPATPRSKQPRQRGASGSVDNTADRAGTGPGGRPTSPPPPTGTRQPSGNLLARRSSGRNSQTVSLLKELDSARNRNAWYASELELARKSGYTPNATLSPVLDSRAETFNEDDRPLIEALLAMRTELANVQSSVDKQAILAAKQIAEADKQRDAAIQEAVYAKAKLAAHLGGNSANSTPQLGGDRDVDDRVEESNRKLATALSLQKDLHTQLERTNAEVEAEKRARQLADDTLNAAQRRMTDLETYKQQTSYELERLKAELHNAQREAREHSVAAAEAVSTAQLLRVDKEDFERQYKEAVGSSKDTSDSFTSLRAAVAASDEMRSLLEQKLEQERAQRETAETKLTSIKADLEARTAEVLSMTQRLRDTEELAEKHANEARTHRQAVLNGLDTINARSVGTPNKADAERLVALQAQLVTANALVKKHQQDADTAAERLRSAEERIAGLEAYQEQSSREGVTIRRQLQAAMRDTQTLQAQNTDLKNQLSNQQLETNAMTVQHNTLKDILSERGISPTNSSRARGSPRESSPEHEARVRSLEQQLATAVAAHEETKQTFAVQASDSEAVYRDKLTQLENDYQSAVHYVKGTEKMLKQLKEQLARYKSENGRLKTEIEELETKTTSTRNLAASAPPPEWDAERSLLSQKVEALQGDLAQSKTQLESQLQNVQQQLEQVKGERDATMTHLTSSRRDLEELHQENALLEQRAQDAEQKVGLLLDQVESSVGNYRRRSRQVASINSEQLREAATGGPNPTSLPTTNGHGNGTSNGNHTTTTTPALNLGGSGLGHERQDSSETGSAYGESVGGDARNSAALDSLANELETLRSHWEATNKNYRLSNAFDFEGTTGAGAGAGGAGAAPSSLSTGLRKDNKDEGGLGLSESLADWRKRLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUC8</accession>
    <name>A0ABR3YUC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1237 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028846">
        <property type="entry name" value="UCP028846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049801" description="DUF1237 domain containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="58064" checksum="1EE0D082362DEF79" modified="2025-10-08" version="1">MARVSRIVGASVLAGVWTAGTTTGQSCPDYSTYSMMAHEPLSNGSYHLGYMRPDPQCRTFNLTDVESTITSMASSISDPDLYRLFVNAFPNTLDTAIRWKGVAADNADEELTFVITGDIDAMWLRDSANQMQSYRSLLKASSDSNSLASLYRGVINLQARYLLESPYCNSFQPPVESGIEPATNGAATDDTVTPPYDSSKVFECKYELDSLAAFLEVSADYYTATGDAAFFGKFNWISALQNVLQTATSMMTPTYGNNGTVLTSPYTFTRLTTRSTETLANNGLGSPVAANTGLIRSAFRPSDDSTLLQLFIPANMMFSHYLEQTAKIVDKLGSSAPKGLGSQMHGLAASLRTAILKHGIVTDPNAGIIGAPVYAYEVDGFGSSIIMDDANIPSLLSAPFFGFTSISDPIYKNTRAAILSDTPRPGLNQYNSNPYFMHGPVINGVGGPHQGPGYAWPMASIVRILTSDDDDEIVSELQTLVSSTAGLGLIHESVNTFDQTKWTRQWFSWANGLFGQMILDLKERKPALLKRGYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUR9</accession>
    <name>A0ABR3YUR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLD5</name>
        <name evidence="9" type="ORF">Sste5346_007543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21692">
        <property type="entry name" value="GINS_B_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031633">
        <property type="entry name" value="SLD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16922">
        <property type="entry name" value="SLD5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007764">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="64"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein SLD5 C-terminal" evidence="8">
        <location>
            <begin position="167"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="221" mass="24857" checksum="BD0C2B7A8AFA7B2A" modified="2025-10-08" version="1">MDIDDILREVDPSLDPIAGQETHDLQALTRAWIAERSAPELLAWPVGLFERVNQRITRQIETVEDMTGDMDPKTNFALIVIQTELERHKYLVRSFLRARIAKIDKHTLHYLSTPALRERLSDTELAYATRHQALLHNHYLSSFLGSFPANLQNLNDTAGNISMIDSPDLDSAVFVRLLRDGAVRGHGVDVDEIVKGEDGDVLILRWSDAKPLVEAGDAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVL9</accession>
    <name>A0ABR3YVL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VPS41</name>
        <name evidence="6" type="ORF">Sste5346_007119</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="220"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="439"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="728"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1223"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="736"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1223"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1355" mass="148988" checksum="D5E11BFBE9C89B01" modified="2025-10-08" version="1">MPEAHTERDDGGEGGGESRSTLTDRRKVADDTTSDDGIAADSSSEATESETSAKKNDKGKGKAFEADDEDNNEDDGEDDDEEEEEEEEDGDDDDDSDDEDEEPRLKYARLTTNLGGLYRNGDATSAFLVAGDKMIVGTHNGNIHVFQLPTFQPLRVYHAHSASVTAISISPFTPPLPNLKTEQINRIVAESAASRPGSSQASTHSPNTSPRKAREPPPILNIPSNNIHIATASTDGNVCIQSLIDVKDVQLRNFGRPVQAVALSPDYRQDRTYLSGGLAGNLILTVGGQSGRSTSTTVGTAAAAASGWLGSMGLGTNTGRDTVLHSGEGTVSTIQWSVSGRYVAWLNEHGIKIMRTRLHLESADAESAWKRIGHVDRPQTEEWDLMASVWKGRAQWIDEATIDADDDVTNQENTTTEPGVASPAAEVLKQQQARDSKAIERLLVGWGSTIWMVHVHPGRVGTGKHAGERSVGRAEIVKILRMDCIISGISLYTQNLLLVLAYTPADPEEDDDDDNKASYKPGHKATTSTASSSSEPTGGIRRRQNNNPPELRLIDLTSQVEVDKDVLSVSRYERLSAGDYHLSVLPSQTAAAAAVSQRGALEAIAGLGADMWNAALNPSKMLFSSGQSVKSKDSNEGATTNSSKATSMASTLRAQSRLGAGLGGQSVHPSLSTTGIKIFMHSPYDCILATRRDLSDHLAWLLEHQEFQKAWELVDENPDAVPSFAEKASDLGSATPDRSTQTTTQASDDFYPDTDLDALSREANAPAEREKRRIGELWIKEIVDTGDWVRAGQIAGKVLRSSDRWEKWVWTFAGADQFDAITNYIPVEPLHPPIPRTIYEIVLGHYLKQDKPRFRELLERWPTELFDINTVVTALENQLNYRDVREDSVEDGERGRDWRIVMESLAKMHEANGRYREALKSYIRLQDADSAFRLIRENHLADALIDDIPSFIALRVPAGRAEKMSRAELEEATAEAMALLVDEAQHGLVRPESVVSQLQAQDLSLYTFLYFRGLWQGDGLREHLRESHDRLALESKAQLDDFADLAVQLFAQFGDRPLLMDFLKSSTSYSFEKAAAACERQNYIDELVYLYSKTGQMKRALYLIIDRLGDVSQAIAFAKEQDDPDLWEDLLNYSMDKPRFIRGLLEEVGTAIDPITLVRRIPEGLEIEGLRDGLQHIMKEHEIQHSISSGVARVLRSEVSTAQATLRNGQRKGIRFEVVPPAQKKATKAAPDTKAAPAAATAAKGTTDKASPTDVGEDNEKDNLPEWTPGHCARCLEAFTEWDTDTLVGFACGHVFHLSHLLGLSTGEVEELGFGVDSELISRRNITATKIMHARLLRDRVRDGCPVCVKKEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVQ6</accession>
    <name>A0ABR3YVQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007315</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17964">
        <property type="entry name" value="DEADc_MSS116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="152"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="380"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="630"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="655" mass="68771" checksum="34FF9ACC47DCA8D7" modified="2025-10-08" version="1">MADQQQGRKPNRRPRHRGRGGGGGENAEGGEGGNGGGRGGRGGRGGRGGRNGGPRNAPQNQGDDGDVAMPDAVNTLRPFPPPPGGGGNSGVSSNNISGVATPMLSEAVPSDTPRFTDINANGTVVDPILIDTITNDLKFEHMMPVQAATIHELLPPKRLDGLVQAKTGTGKTIAFLLPAIQTMLNKQQALGKARGGPSTRQNNHISLLVMAPTRELAMQIAKEAKNLLQRMPDYHVCIAVGGTNKDREEKQILSGCDILVSTPGRMLDHVQGTPAIKEALTHLDTLVLDEADRLLDMGFLPALKSIVACLPDKVSTKRQGMLFSATVPSHVAQVASLVLSPGYRSISTIPKGEASTHARVTQLLVEVPTFADLAPALVGAIRREQQQLVSQGAGGTFKAIVFAQTAALADFYGYLLANLPDMPPSWTLHARHAQSKRTNVTNAFRGAATGILVATDVVARGMDFPAVTTVFQVGLPMDKESYIHRLGRTARGAAGSDPSKQGGPDAASSGVTESGRGVFLVASIEAYFPTRVLREINFVREEPDLSSTEQLGPIIDRMEESMVGKTYQAWLGYYNGHMKGLHWDKALLVAAANEFARDGLHAVSTPAIQKSTVGKMGLRGTPGLVVVADAPRPHRGGGGGRGGGGGGGGGRGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWD3</accession>
    <name>A0ABR3YWD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division control protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC3</name>
        <name evidence="6" type="ORF">Sste5346_007163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="205"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="525"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="525"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="581" mass="65702" checksum="38664DC7E7CE2EDD" modified="2025-10-08" version="1">MHFDLGSHIKSRSRSAQLEKTLASVAGMGSMSLSDRRSRPTLDAPHSAGPLTENANIANVGGSLRGIPGHGPRPSEPTVHFDVEPPKLLPAIAMTYDELYAKTESEGEEEAEGEGEVTNELEAEKENTNPEEQDEEKGDDENEIEDETQEPLASNGSAPSPPEAMAPQAPPNVSSESQNIVRRKLTGYVGFANLPNQWHRKSVRKGFNFNVMVVGESGLGKSTLVNTLFNTSLYPPKERKGPSLDIIPKTVTIQSISADIEEAGVRLRLTVVDTPGFGDFVNNDESWRPIVDNIEQRFDAYLDAENKVNRMNIVDNRIHACVFFIQPTGHSLKPLDIEVMKRLHTKVNLIPVIAKSDTLTDEEITAFKRRILADIQYHKVQIFEGPRYELDDEETIAENNEILSKVPFAVVGATNEITNADGRKVRGRRYPWGVIEVDNEEHCDFVKLRQMLIRTHMEELKENTNNILYENYRTDKLLQMGVSQDPSVFKEVNPAVKQEEERALHDQKLAKMEAEMKLVFQQKVSEKESKLKQSEEELYARHREMKDQLERQRQELEEKKSRLESGRPLEKEGKRKGFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWG4</accession>
    <name>A0ABR3YWG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aromatic-L-amino-acid decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007193</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="58496" checksum="CB294E830807E83E" modified="2025-10-08" version="1">MDDNAFREAATASIDEIIKYYASLGERPVVSTVEPGYLRKLLPDAAPEQGEAWNVIRQDVEDKIVPGLTHWQSPNFFAFFPCPASYPSILGELYSATFAAAAFNWICSPAITELETVVLDWLAQLLGLPEEYLSTGPTRGGGVIHGTASEAVMTAMTAAADKYLRAALAADHPGFETLAKEEKEDLRALRRSRLVALGGGTAHSSAKKAAQVLGLRYRSVPAPAANGYYINGDGLRETLAKVRAAGLEPFFLSTTFGTTDTCAVDDYASIVEVLDADLKTQVAAGRDAAASDIWVHVDGAYAGSALVAPETRAIMCPAPLDPSNPNSEATGTAVLRRFHSFNMNMHKWLLTNFDCSCLFVRDRRWLVDALGADAHYYKNDYSDGGLVTDYRDWQLPLGRRFRSLKVWFVLRTYGGEGLRAYIRRSISLGERFADSLKARSDLFEIITGPQFALTVFRAAKLTADEPLEVTSARTRRVCELVNGGGKIWVTGTTLEGGVAAIRVMTGNFSTHAEHVDGASKIFVETAEKVLAEEKAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWJ2</accession>
    <name>A0ABR3YWJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zcf27p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ZCF27_2</name>
        <name evidence="4" type="ORF">Sste5346_007102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="659" mass="72830" checksum="50E677BC54FA5F22" modified="2025-10-08" version="1">MHAPLSSPSPADHQEPAASTSTSSTTGKRKLPRAAATYPRKRATQACLTCRFRRTKCDNARPSCAACVRLGADCSYREADHSTFDPASLTILNRLDDLERLFKQRQAGDGPADAGPSAGLPTPPIPAAPLLAAVAASAHDATSPVSQVSQAQSDLSYAVDVWSREKRPQVSIDAVLQWGPLKDEGFTTRMFPAPRRDDGASPEANGSGNAGGGWRGAIDLDLPAADAVLRSFFDNVHVFNPILEEEDVQDYVKMIRFQGIGWDAVSCLTLLIYALGTVCTMFGRDYAGEVALPSVFRQSAAFHEAEAYFLAAQKRMGMLLCRSGVIDAQCFFLAGVYLMTTLRPVEAWKMFVQALACCQGFLVPDEVSATSPATESGGVAEDGSNPKRRIYWACYKSELELRLELNPSQKDVWDLTYPTFFPSPPDALKARDETAWYFYLAEIALTRLKNRILSHLYKSDKQATRESNIEYILDFEEQIHAWLGSLPPPLELTSTIDGDDTDTSGKDDREQNEAFRFVLNGHLLDCQEIMYWPFVVDAVHGRSTSSKYTAAGRHHVASFLRKGLRVCVDRIRQSRQGFRHRHHGTWLMLRSSTRSALVLLAVARCPSLAAQDTLPHGWDDRVADVADMLQLWQDESSDVQAMLTAVETLLRTSPMRTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWN9</accession>
    <name>A0ABR3YWN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF55">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G01900)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="270" mass="30327" checksum="A262425FE14E4CD1" modified="2025-10-08" version="1">MTTMSVCCVKGFKWEGTPEGRTEKIANGKYDAYVAGNNPDAAVLIIHDVYGWDNPNVRLMADHYARNTGATVYVPDFFLGDTLNRDKYPELSNQEFLGKYLMPFIGRHPRDVREKDIFAVTRALRREHGYEKLAAIGFCYGGWAIMRLGAKPEDQPEDEDKDAKPIEGPLVHAVSTAHPSLATEKDIDGVVVPLQILAPETDQMYTPALKQFTFDAAVRNKIPLDYLHFPGIEHGGLMRGDQKTVESRQALVRAQYAAVNFFKLHLDLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX08</accession>
    <name>A0ABR3YX08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="60" mass="6446" checksum="7D643C55C242A73C" modified="2025-10-08" version="1">MPSTDAPQQQQPMAVTTDNSIVTEQPSLQAQPEMQPEATMRGGFFEECGCCGCNEECGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX40</accession>
    <name>A0ABR3YX40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007026</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="64308" checksum="FB761BFD10AE366F" modified="2025-10-08" version="1">MAGFRWSHLYRPPDLNPINHKARSIPVFNPINMYGRVFFFSWFGFMAAFWAWYAFPPLLTVTIKADLDLDTIQVANSNITSLCATLLIRVVSGPLCDMFGPRKVFGGMLLLGAIPTGLAPLVRSANGLYVVRFFMGILGGSFVPCQVWTTAFFDKNVVGSANALAGGFGNAGGGITYFIMPAVFNSFQDHYGLADGPAWRLTFIVPLVVVLATGGALLVLCPDTPDGPWSEREKQAQQHLAEHHVHASQLQEGNTVPTSTEDAVGRDNTSNGTPPDALSLPGLPTTEEDKIPQVWQSHSHGHNRHSRHPTPTLGDSSSSGSSSGSSGSTTTSSPQLQAVTHTASRSSHTSRTSRTTSHEVHLSEEQMLATARGEIVQPPTRAEVRRVVLSPHTWALMLTYMCSFGTELAVNAVLAAYYLRNFPELGQTGASNWAAMFGFLNFVTRPLGGVVADLLYKSINSLWAKKHWITVCGVLGGVALVVVGRVDSTHKPTMFGLVALAAIFLEAGNGANFALVPHVHPFANGIVSGLTGAAGNLGGIFISVLFRFVTRVNDDVPRNSPMADYDRAFWIIGLIHIGVYVAVSWIPPIPKHQIGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXE3</accession>
    <name>A0ABR3YXE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Phosphomannomutase</fullName>
            <ecNumber evidence="5 10">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PMM1</name>
        <name evidence="11" type="ORF">Sste5346_006828</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 10"/>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00445">
        <property type="entry name" value="alpha-phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01143">
        <property type="entry name" value="C2.B.3:_Phosphomannomutase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="268" mass="30079" checksum="AD132FBFE78C2D13" modified="2025-10-08" version="1">MPDASSYPPLAERPIKNTVVLFDVDGTLTPARLHASPEMLDILHRLREKVAIGFVGGSDLAKQQEQLSTPDVPVTDLFDFCFSENGLTAFKSGKSLPSNSFIKWFGEDRYKEFVKFVLHYVADLDIPVKRGTFVEFRNGMVNISPVGRNATTEERLAFEAYDKEAGVRKAFVAALREKFGHHGLTFSIGGQISFDVFPTGWDKTYCLRHLEEDAKKPGGIEYTTVHFFGDKTFEGGNDYEIYTDSRTTGHSVTKPEDTMAELKKLFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY93</accession>
    <name>A0ABR3YY93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145809" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="159"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="467" mass="52587" checksum="2031E9BD04AF37D7" modified="2025-10-08" version="1">MTKGALLFWLTTALALITGTAASTDAKVDLPLPQVGHCVWSKYGYPMPTTGLDVCPRPVSDISSNFAPWSYPPYCIHAPMNATVTDPNGGEGAKLSAGRRKYCVYTSLTFRGRGLSVISTPQGAANLVASLDDTRVLPRLRDHPASTMAKRDARRDAGRPYVIKNVAQGHGKGLVARRRVPKWGEALIGFPIMMARTDFLEALPDADRKKLEDRALQQLPTMAQEAILNLAHGVAGSIDKEFLLEHIFRSNIFGIEIAGVHHFSLQVEGSRINHDCRPNTFWRYSPSTMTHEVVAFREISIGEEFTHSYLPLGLALKDRQESIRRWGFACHCSLCMAPRNVAFASDIRRTRLVEIYTTMEDEAAEGMLTRDKIETLLAEMMLLINGEDLVPQLCEYYAMIARAYLSIEAFDDARHYAQQSEEYWIRYGTEEHDNVDEVRALWKQIEAKEKAVNERRRRQEAARSREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ4</accession>
    <name>A0ABR3YYQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="440" mass="45070" checksum="1D45DB8FB44A987B" modified="2025-10-08" version="1">MTPTQTPALVRAAAPNATAASVLPALSDRRNSRPSSSTAQRTGPNPAVATPKQATPQHPAQQRVSTPASNAAAGPSNGTPSGPGTGKPQLSLFKNTVVPTATHPVSTASNPPAQPRLGTFSTSTTPHPSTLPPKRPTPVSVPSPAPATTATPTPASSAKNGSSIPVSSLPTTSASTSSAAPQPKSDGQPAPRPAYTMKRTGRPGMLPPASMHSSGSRTPTPSGSTTTRTPTDTPSRDSLNIKTQPPPQLQSRLFSQTSTKPALIEIDLLQNAQIPISSTNGQVNGIKRSRESAVNIVNLAQPAQKRAKSTRSSSSPEDVTANPVTLTVSLSSGPEDSSDSSDSSDSSDSDSSDGDIEDTAVPDIAAVVKGNDNSSLSDSIDSDSNLSYEEDEISEDDEDEDEVSDSIEVGDDEAEAVLTSAAPGIFTSAPSGRPYNKYQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZR9</accession>
    <name>A0ABR3YZR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RHO2</name>
        <name evidence="4" type="ORF">Sste5346_006385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="201" mass="22196" checksum="EA8F617F15EC5B87" modified="2025-10-08" version="1">MASTSAARDVIRRKLVIIGDGACGKTSLLSVFTLGYFPTHYIPTVFENYVTDCRVEGRNVQLALWDTAGQEDYERLRPLAYAKAHVILIGFSVDTPDSLDNVKHKWIEEATERCPGVPIILVALKKDLREDPLAVEEMRKKSQRFVTKHEGESAAKEIGARKYLECSSLSGEGVDDVFEAATRAALLTFDRSEGGGCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZT3</accession>
    <name>A0ABR3YZT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="196"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="135"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="491"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="627" mass="66311" checksum="0C3FF042C2125263" modified="2025-10-08" version="1">MDVDAPEAPSGDDAKAVNGTADGNGTNGAMNGAHNAHDAHDAMEIDKPQPAKQEEDQQSNQKKLSSSVQRPPSSSSSPPASPSPPPPPPVVRQIYTPQFSPAMAKLIHGEGGDSLSYKNLAKHGVRTISLGIKSLSPEELSQPRTMPMPVSRKSPGPGPGPRKRRQGTPNTDSTISDFLEDQSTPSLSPETVQGPLCTVCDRPARSIFNPLVPCRRCGQRWHRLCHDPVIADYVAAASAATTDGAAVNNNSTPSPASPADAGPSSSAGGWSCPSCVSATTAETTARLARRARAVRPANSLSLPTRPPPPAHHDVRNLSRQQRHNYLAGLSRPDLQKWLLYAMEKNPEVAVFPPRPPPIAVTTAAAVAATSTTVAAGAAPRRGRPPRSMFLPPLPAGMAPPHGGRVTAAAVMSATKNSQEYRDRIVRSIRKGHAELVAEAERRERAEKMAQGLHVPRRRGRPRKASLEAAAAHQARLAVQAALAQQPVSAQQIQAQPTVTRPAHLRQPQTHPPSASQMSRTHPPQPASQSVKVVKAMPTSPSHIPAFEPTPVDPDEEDPMGLMAGWPKPGQGLYARVGPDWDTSVNGDDGNSTGRALISTNDHASFSSMVFNAAGRKVIENGAPVLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZX0</accession>
    <name>A0ABR3YZX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="112" mass="12662" checksum="41C6CBB720E389A8" modified="2025-10-08" version="1">MIDLSPLGARQPPLPPLPPLPRPPPPPQPPAQSYASHQQQQRQQQQQQQQQQQEQQQQQQQQTRPLEDHNDPFYRLNFDSELVPRGTGTGDSQSSSKGELNSDRAEARPKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0N4</accession>
    <name>A0ABR3Z0N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006243</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF4">
        <property type="entry name" value="ACETAMIDASE REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="36"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="660"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="725"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="803"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="660"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="725"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="749"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="810"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="894" mass="97410" checksum="E344874210BA9313" modified="2025-10-08" version="1">MQTPTQGQGMTRAQANAARSTCTACHQRKVKCDAHDRGYPCTRCRKNGNESDCRLHKKNKRVSRAKQQARQSTSTQDVKPLSPAPPQAPASIQQHSSPVATVHESIVAVAAAPTPAAAATPGSLFLQTVIAEGDSGEHVEHTAPQEPASTPRTPLDRIEHNDRFDHDHDYDHAPHSDTGTAGSTTTTTASTPAVLPSHGADGEYKKYLVEFIDQPQLAERPIDKTARILYVGSSLSNIHFLLRQRMSANGANPKKETNEENVTCASARKEDTAVHYPTNRIAKPSAGLGALAADGLPLEAFQLPPKRTVDQLLGVYLQHINPGFPVVDGRLFMRQYRARDPANPPSLLLLQAMLVAGAHVLYKDDPDTRHTQKAVFFRRAKMLLDARVERNRDTVVQAALLLTWHADGPEDVAANAWHWVGLAARTATGLGMHRDADGSTLVAHNKRMWRRVWWLLVACDVLVALQYGRPPALHLDDTDVAPLTASDFVDCGSGTRVDYVLHLVQLCILLSTHVLRRQFRSTYSSSSREKDRQSALRRTDEALANWSLHLPPSLQLSGQSDPTSSSASTSINVWTASLHLTYNTALLLLHRQAPSPHAALDTKIGGPSPDDVEICTNAAVAIQQIFHAVCASGQAVYLWSSSINSLFTALIQLSGDVQRSTSTTSAPTIKSSSSKSRSRGNPLLAVAALRRYDAALASLRQLAAFWPNAQAVVQFFEQSVRTGSASAAQPTSGDASATSEEMQHSGSNTTTTTTVDSTRHTTPVPDLPQVTESVTVTKDFAAYPSVDPSADMHLEMDTVDSRLSHSHSQSYEDHHMPDHHVSSHGPSDPDMAQHLLSSFVAAARPMLPFEGHHHHHHGHTPPMADPWNAPGANADWQCIYWQQPELTDDFLFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Y8</accession>
    <name>A0ABR3Z0Y8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_006116</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046541">
        <property type="entry name" value="DUF6606"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF34">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20255">
        <property type="entry name" value="DUF6606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF6606" evidence="10">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3638" evidence="8">
        <location>
            <begin position="1973"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="9">
        <location>
            <begin position="2324"/>
            <end position="2357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2781"/>
            <end position="2808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2785"/>
            <end position="2797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="3049" mass="341598" checksum="590E698A9D71CBF8" modified="2025-10-08" version="1">MISRLQQTRDDTTGFLYEDDVSKALHEVVKDGGVLCLPIAAQNAGVVVSRTGDDDPLVETFELSPPHGPVTSTKGRLTRSFPGPAFFVDTPTARHGDFQRAVAQVLAQMSCQDTADVKARTRRTRRGDDSSDDKDTKDPVLVTELLANMFMAAGKPADIPSITKNTRDEAMWSGTGRPWRRSSMYLLLRLSLQSFFVRSTGNDDLYKCFMVYYLASLVRSFAVDQLDTDILHVLVSKLQRRVSKLGDKTVREHAWLQSVTVTVKSTTELISRRWEGVQRTDRRPYGEWLSSLKTVDLDKDTRLLLPELEQYLSDLRTGDTSNNKTDFVPDPSRRLPLFLPDTLPVLDDTLPADYHHFQLLALEAWVQNHMGPWIQATKDRPDTCRALFKCMKEYHKAAQDEYAGNPECLSHMVLTLMELWAACDMAATAQCTLLQDYDHELPGQVLQALLLPRGAQMHRLARMEAYLHNRSEEASCQSSVFRSFCTDSSFGVRYFDESPHHQALRKEIEKHARHERRQKIEELAAKTKEYHHLQRLASTTRCDYVRRNDGYGNAEQVHHPECRRHNFVKAAENLQIDVHEWPLPDDELEAKSTVFELQVPKTVSAWRDATLYVTHDVLGSIVNDPTSLDTDYSPRVYTGLRGWFKGGTHRLGLRSTTKPYVVTNGKSVALADAPTQEDVCVPNGLQYIYFDTVLGIVSDAPDPTDKLTDGCTYALPETSASLQKFLRRTWSAPHGCPPNEALADQYACPEHMNLDAFKALASLPLGLNIQWQNVLVQLSMPAVEFRQMETCLFVLQVVYQAGPPGRGDWAARRGHVVLHDEAFVGALLDAVFDTHARIKDNWMAHLTLGILVWVTTRVLSVSTDEEARLRCISFLADARQTAVAWTRLLSERASSSTRDDEREQFRGQALDVALVCISSFDVDGNVFESLAAEDVAILLECSMLVQEKKPTTIDSSDTLKVLLLARWRHIMYEHRERLQTSSTTIANPLDKAISQSWTTHQPGPQWQPLPQPHQHLLVSTGDNDDVPTLHFNLLTAEFLVNGSPLARLPPDYEAHPLYQVLFGNTALEVMPSTEPGLRFAGKTLYHGHQLQFALREGDLTVRATDHDGRVWFLLPPRLFHNYFPTSFVEEHVHWVDLDKDTVEFRPIDRPWLSAAQLWTLSSVDSDRRLSKSDGSSLANIHSKTASILHQTLNPLEDALNIHIVHVPSTNSLEIELPRLGISFLLAAGSDLLECRQFRDYAVATSQDVGTLVGLQSKLVVEHKLSAKKMVLIPGGQIEFKTTSGHTSVSVVHGTADRVQAYEIDDLLGSVVDNGDLPSKVLLCYLHALTSHCLPDRLTGHTGTEQALSILESASLLSFGRLDRTSIDLLAKIAALSPARHYYPSHLTMAQSVDWNSKLGFLAQHGGLFTAVDHIFQEYETSLIFYPEDAPFFNETWDSLRKTVDRDLVERDLVMSSFLRLSGFGAEASLTRQDRQYSGRDAQLTDPERTARVYTAARLAMSQYPAGHIPLPPNTDLSSTLFRLLRGSSARESTQGPDASLGDKCIGYDAAWLKNMAVLFIRHWCRVHKLLASGSVDRYTFGVWLATLAYNSSADMQALQTLWVVFSQPAVGVSCAPPPRTSFNLFVGKEPVRSDLLDVVNNALRPFSSYSSPEAKTMAGASLDLQRRTYETARLQKRDQFINSLLAAWPTSLPPTPSDTNYHEYINTLEAMEGVVPLFRLWHDNILFGEYLDGLARGVQRCRVLPVTPPDVSPPAENWPSRDSGYAFVPLKSVFQSPVVVLRPRLVSSYINDIQPRPLPAVQNSTSSDDHLDKLSSMFERLHVQAQSDNERTYVDKLGDSLQSLQKYEAASRRSGRWRQAGSSTAVVHAPDLKYRLQKHLKACRENVDTLYKNLVRSYKMALPGLRQFPRLSPTVFLSQLCTRRWTFLSTEWKTAIVDYALALVALHRATRLLSLSGPAHEAEFNKELANVGHTNWSPTEHPEWLLLEVESGITIRAVQRDIAAHMSSSEKGNVVMQLNMGEGKSSVIVPMVASSLADGDSLVRVLVAKAQSKQALEMLVAKTSGLLGRRIYHFPFARPVHLSSPADILRVDKMLRDCQTQRGILLVQPEHILSFKLMGIERCMNGQTDDGIGKAMLATQHYLDHVSRDIVDESDEIFSAKFELIYTMGTQRPTELSPTRWGLLQELMDIVGVAVAQLKKEMPDAVEIFVEDTRWTGRFPRTRLLKKTAYPRLVQLVGRQLCQRGLHGFPIALQPAPIRQAVFRYLTKLHLTDEEVAAVETSSFWTDTTKGPLLLLRGLLAGGILSFALGAKRWRVNYGPAPANRQPPTQLVVPYQSKDMPSPRAEFSHPDVVLLLTSLHYYYAGLSDEALFASLHRLVNTDQPEDEYTAWVKTARSDMPPSFRQLSGVSLADRWQCTDRLFPFLKYSKGAIDYYLAHIVFPAHMKEFPDKISASGWDLSTSTTVTTGFSGTNDARPLLPLSVTQLDLPQQSHTNALVLANLLREENGVHLLEETGAEALLDAVVSMHPPVRVLLDVGAQVLELSNLQAAQRWLSKVEAAEAVVFFDDDLLSVVDRRGRVEPLQASPYAKHLDVCLVFLDEAHTRGTDLRLPTHYRAAVTLGADLTKDRLVQACMRMRQLGQGQSVVFLCQPEIQEKIQSLRPDVTTPTVSEVLSWAIHETQQELFRYMPLWALHGRRFAWQQSLWKGATKTDGYALTNDEAGKFREVEAQSLAQRYLPRNSRQYAADGEHNAGLADASTLQAIDDRCRAFLRDDTDTAHASLNEEQERELAPEIEEERQKARPPQATALKHSVHPDILYFIKTGDIRQDSEAFMPAFHTLGETSIANLVDLNRLSSQPLATLDFARTVRPDGTNWMDAFQRAPQYILTSSVSSSIDHLILVSPFEANEVFSYIHRKRASPAVRLHLYSARVNMAYRPLDRLELYTVGSQASALLPREVSISLNLLAGQLYFDSYQEYADTATFLGMAHRISDASAASSSSAGSSAFFKALMTQLRRQSASIDKTHVGKLLDGVLLTEEDFAVDTVGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3E3</accession>
    <name>A0ABR3Z3E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="563"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="595"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="459"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="600"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="663"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="737"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="811" mass="86758" checksum="E5709C759EC33BFF" modified="2025-10-08" version="1">MGYLSYAEPPHNRHLSLPHTPPDFVNYACSPTSSSHGLPPKDLSWPHPKPPISPPMSSHDQQLPPPPSARRSRSPPRTASPSSVGGGSVGGSISSIGLSMAATAAASLARASISAITDAARAPSGAPSGAARTTSTEDRSDSTPATTTSTTTTAATTAATTAATTATASLTSSPRHEQPRLPGAGAPVPPTLSTNGPLPERLPSLTSIFGPSSLDRPLPPTLAPSSGGPPPLVSGAPTSSYGQRPYQPYDQHGRPPSPGPAYLPPPQSAPSQQAASGRDSYSSSSGYHHHQQQHYQHHDQRSPRSEDRQPVNRMYQPPSPRSHEHEQQQHQHRHSHQWPDSRSDYVAVGKWSLQDGPKTERSYSDSKPSAPYQQQHSPGSHRYSQPLPPPPSQQQQASSSDDYYRQQQHQQHQQGPLPPSQSYSSHKSTQLPPPPPPPQQQQHHASRSPVRRPAGVADGRPSSGSVGSSLPSTPASGAFPEGGAGVGAGVGGVPKETLSMGPKIWTGVDFLPQFMHASEVPGEGTCYFYDDGTHCKAVIDGEAVNPYWGVTKAGKPRKRLAIACMTCREKKIKCDPEYPRCVQCEKFGRVCRFKNAPRGGNNNSPGTASSEPDAHRKINSGNTIHPPPESPSASGPGPNNTNNKRMRSDYDHYTTAGRGRSPPFSNRSPTLSNPSSSADPMRHNSTGSNSNVLPPPIGYSGQPSHSQSSPLPPPPSSYPRSTPQQPYSPHSPYAQHGQLSPRSQYPPQSYDHHHSYHHPAQPRSQPGSPSQPDLPRMLLPPPRSAPDLPRVHDDVMRRSWQSDMSRPHGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K0</accession>
    <name>A0ABR3Z3K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mcm7</name>
        <name evidence="11" type="synonym">MCM7</name>
        <name evidence="14" type="ORF">Sste5346_005353</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="395"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="756"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="834" mass="93020" checksum="63F3E60BA7DFC82A" modified="2025-10-08" version="1">MAEKLPTYKKVVEYTLQLAAFKDFLSNYKTTPEHAITHALGNINIDDDDLSDEYEFVDETDEAAERRAQEKAARRKPTHKYRDLLQKLADREVDEVIVDLDDLSMFEADTQNGLKLTQSIEMNTKHYVEILSQAVDELLPEPSADVSFKDDVLDVLMARRKLRNRELRDGAEALGDPAMLDDVFPAELTRRYTLVFKPRTSTLEHPTKPVAVRNVRGEDLGHLITIRAIATRVSDVKPIAQVSAYTCDRCGCEIFQPVNNKQFAPLSLCPSKDCKENQSGGQLHPSSRASKFQPFQEVKVQELAEQVPIGQIPRTLTVLCYGSLVRRINPGDVVDISGIFLPTPYTGFKAMRAGLLTDTFLEAHHVVQHKKAYEEMTIEPQLVRRIEQFRQSGQVYEYLAKSIAPEIFGHLDVKKALLLLLVGGVTKQMGDGMKIRGDINICLMGDPGVAKSQLLKYISKVAPRGVYTSGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDEFDKMDENDRTAIHEVMEQQTISISKAGISTTLNARTSILAAANPIYGRYNPRISPVENINLPAALLSRFDIIFLLLDTPSRETDAQLAKHVAYVHMHSRHPNIGTADEIVFTPHEVRSYVARARTYRPVVPEEVSEYMVKTYVRMRDQQKRAEKRGKQFTHTTPRTLLGVVRLAQALARLRFSDAVDRYDVDEALRLIEASKESLNAEIIGGAGPGAGRRGTNASSRIYNFVKSLADTGACRPDNNDEDGDDDDDEDDTAGGRGVELSLRRVKERVIAKGFTEDQWLTALEEYAAIDVWQTAGNMSRLVFITSNDAEDDMEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z456</accession>
    <name>A0ABR3Z456_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PCL1</name>
        <name evidence="4" type="ORF">Sste5346_005224</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="3">
        <location>
            <begin position="86"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="441" mass="48789" checksum="FC29B1A069DF65E7" modified="2025-10-08" version="1">MDSTQLSMAELNAAALEHFVFTPVNRDMIRYLADAAANVIQCDPNMMPPTASEVQRRSLPTPPGSPSHSPAPRAVRREDGGLPSLEEFIGQLVVSSNVQVPTLMSTLVYLNRLKSRLQPMAKGLRCTTHRIFLASLILSAKYLNDSSPKNKHWANYSVITTEFYNFGFSRTEVNLMEKQLLFLLDWDLRITEEDLYTDLGDFLAPIREDVAARYTRRQQRRRRQKLLLQQQQEEEEAERQRQAQILAEAEAIAQAQARQKRQEEDAAIWAAATASAAANGYLTPPRRSSHISLNLNLTPSPVTSSKATPDENSLMSMPSLTYSASTSSANSYASSLSSSRSHSRASTPQSLVDLDAAYAASSPYYEEVVGTPNSTNSTSSLKRERALTKDSITGGKPAPAAYLPYEISLEELRDIQDGGNRVKRVRGMLGRVFGSSGVLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4T9</accession>
    <name>A0ABR3Z4T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="240" mass="26344" checksum="F7821F0EAFD39179" modified="2025-10-08" version="1">MADTPELLYHTTLVVYDGSRDPTNRSRSAFILGTHTSLAAAKAFSTTALQGLGYKPSDFLEYHVKEPSSQEEDWIFGDGVVVYAKAFSGEEFAVGLDTTPNDQGFAGAADGTLILQGISSDHNPAHHLHYVLQTKVDYDQDRCRARRCSGTDMSAFKSTEIQGCFLKRADAIKAAKQCLKSAGYEFAQYDERNDLGKEDDWPFGEDVLVHAVSQTGENYAVAVRTISGAHQKHDKKNCGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z519</accession>
    <name>A0ABR3Z519_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557:SF2">
        <property type="entry name" value="NUCLEIC ACID DIOXYGENASE ALKBH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="252"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="386" mass="43715" checksum="01FE4814FDEEDDB5" modified="2025-10-08" version="1">MTADITSLDAHEQPSEYLRSKWKTYAKSSVFDIEKSKDIDEIANGEEGGKQDRTAFVPVSTLPADRIKAAFEQFLADKSPVDGDIEEDEEDDKKDGTSSSDIPVYAHPLLPGLLIIPKLVPLRVQKRLLDRMIHRDLADQRHQTNMHLHYNLPYPADGASFFTYPPPANAHSVDVLQGPGTFPPKDPSVHRPLSIQQVLDKRLHWVTLGGQYDWTNRVYPGKEGEEEDEEEKVPSFPPDLIQLLAGLFPETDAQAAIVNFYTPGDTMMIHRDVSEEVDKGLISLSIGCDALFMAAPTAEFEEEPRPERAPTDKEPYVLIRLRSGDAMYMSGHARFAWHGVPKVLKGTCPEELVAWPAGEHSDERYEKWRGWMRNKRVNFNVRQMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z613</accession>
    <name>A0ABR3Z613_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421273" description="CBM-cenC domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="25637" checksum="FD73A699C62D6F64" modified="2025-10-08" version="1">MKGFFSILVVGLLAVDGVIAGNCRPSKSASSVSSAPSSASSVSSVSSVSSPSPSPSHNPCDNMVVDGTFTNQLVGWDMSYSEGSARWTTQDCSPTCAHCAELEALDGETTIYMAQDITLTAGVEYVLIYTYYKEVDQTGGNNPTFTCEIAPSQMGARRSARDFSSTSPASPLLHKRVGAVAPQGMPLAEKRSLAGRAAAAPAFTIETKLYTPAIALNTLTCTMWSLGISTYEVGQVIVIPASCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z632</accession>
    <name>A0ABR3Z632_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004818</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="57"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="553" mass="60107" checksum="93230098FBEBD225" modified="2025-10-08" version="1">MKDIDTAKNASAHVEEAGQSAGVVLNRNDFEQAQLDTLGEGSPPWQVIKGNLRACATIFVVQLNGVILGLEYALLGGLVGVQAFCRTMGSYDEATGTYAVADNTMSLWGGLFGLMQFLGQIFAGWFADRFGRTWCVYLMCLNVYLGVMTEILSNNKYDYLGAKIIMGSATGIMQVVVPTYVAEITPREIRGISIGMFAFNLSLGSLIGTVVTYGANQAYGANPFDDRGWKVPLYVGLAAPTVALVGMLLLMPESPYWYVLKNRVTDARRSLKCLHPNKTDEEVDRLCHELQYTVLKESDDQASSRDATYWECLKGANLQRTFSALFPSLAQQLVGNQLIQSYSTYFFGIAGLSNSLFGSVIVSVVGLVSAVIAFFLIEMKSVGRWHLVFWGVSGITLSMLAIGIIDSATNTTNASAGGAYVAFVALFNAAVTIGPGVAGWAYCGETASARLRAKTATLAVGCNAIIGTITNIVIPFELTAIGPKTGYMFFGIGVVCCIFTYLWIPDITGRSFSQLDELFERRIPARRFKDAICTGQYGHEHSKHDEMDKQNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6S5</accession>
    <name>A0ABR3Z6S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_004720</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016958">
        <property type="entry name" value="DUF858_MeTrfase_lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="248" mass="26882" checksum="E12CF51BAC8AA4B5" modified="2025-10-08" version="1">MSDEQLPPTASADATPEARVNNADAKAYWEAISADDDGMLGGFAFVSRADLRGSRTFLAKLGIGSKPGLRRITRALEGGAGIGRITEGMLLDIADEVDVIEPVAKFTEQLAGKPGVRRIFNVGLEGWSPEADSTDGGTGAGLPVYGLVWTQWCTGYLNDDQFIEYLRRCRTVLEPSTGVVVIKENLTNTGIDDFDTQDSSVTRSEQSFQNIFAKAGFRLVRSELQRGFPPEAELLPVKMYALKVKEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6X6</accession>
    <name>A0ABR3Z6X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005031</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase S53" evidence="12">
        <location>
            <begin position="221"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="551"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="64557" checksum="7D9254D8658A444C" modified="2025-10-08" version="1">MLAPFLLFASVASAKVFHSLPSVPQGWSLVRNASPSDAISLKIALHQRSAADLERIVLEVSTPGHPNYGMHLTRDEVRSYTAPSDAAVDFVSVWLRDNGIESSSSSVKVDNDWVSFTTTVDRANALLDTKFDWYQYEDSNSPVLRTLEYSVPDALVDHVDLVQPTTRFGRFSTHRSTVFSMEYVEDKADEAENNENKETGSVKSTLATAANEAAVASCNAGVTPKCLHDLYNINYTVTNPAENLIGFASYLNEYARYSDLQLFEKYYVPAAKGQNFSVTLINDGKNDQTSGYDSGEANLDVQNILGVSHPVPIIEYSTGGLGPLVPTPDEPTQPGSNEPYLEFLTYMLALNDSALPQTLSTSYGEEEQSVPEEYAYKICNLFMQLGARGVSVLFSSGDSGPGDACVRVSDNKPYFQPTFPAGCPYVTSVGATYGTGPERGVSFSSGGFSSLHPRPAYQDAAVSTYLKSIGSTYAPFFNASNRGFPDIAAQGNNFLIFDKGRSAQLAGTSASAPVVAGVIALLNAARRSKGLSPLGFLNPWLYNNTAALNDITTGAGEGCTNTTYFASPALWNATTGWDPVTGLGTPNFPALLEAAAPGVPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7G7</accession>
    <name>A0ABR3Z7G7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF2">
        <property type="entry name" value="B, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="1">
        <location>
            <begin position="397"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="835" mass="94554" checksum="8FF23FA1DC743860" modified="2025-10-08" version="1">MAGHQVDTTWMWHPLFEEHRTDTAGLFVHFKRDVVIEDEPPASFKVHITADTRYKLYVNAQLAAFGPVKGDQHLWFFDEVDVGPFLKRGANKVAVHVLRFFHSTLYATAFPRLPSGGLRMVALEPDSGLGRQLQSSTTWLTAIDPSTMLRVDEPEDDFLHIYERRVWGGEAARLHWVHAKVLEYQTSTGNSTPWVLSPRQIPPLRRQKSRFSGLHNIQSSAEHEAWKRVFFIAGGESVDGFGDRPQEHHHLRLPAGSHHKVDLKAPHHMTGFLRIRFRRPQTGGTVVTLLYAESYEDKPTLVPYLRNKEKRTDSSKSLFGPTDSYVLAGADHVERLGYHEQDDVDEVLLPFHFRTFRFIQLDIRVGDSDLVLKEFEIETVNYPLDVHAALLVPAEHDKLSEQLWTTSLQTLLNCMHDCYEDCPFYEQLQYAMDARSSCLFTYCVSGDDRLARQAIIQLHNSFQPRLGLTCSRAPSHRAQVIPHFSLFWICMLSDHFVRYGDERFLAPFVPVVDAILGYFHAHLDATYDIVASDLGPGLWNFVDWTPEWRPYGIPPSASKTGISTYSNHLYAYALKQGATLLRALGRAHLADEYAVRADRIVAALRRHCFDGQFFTDSLASGADPDIDYSEHAQVWAVLSGAVEGEAAQVLLRRCLAGHPEADKEVQSPTFIKTSISMSFYTLRALSIAGGDLYDTLFHTFWGPWRTQLDNGLTTWEEDTVSQRSDCHAWGSAPLYEFMAEVAGVRPAEPGWAAVAFQPRLALYAEFHATVPMKMIDGVLTGMVRVSWATDVTSRKKTVRLRIEMKNDTPPPVVHVLLSSFATQYIPETGEMVFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z802</accession>
    <name>A0ABR3Z802_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="3">
        <location>
            <begin position="56"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="163" mass="17299" checksum="6664C1E8275E4EB2" modified="2025-10-08" version="1">MLNNLRIVRSCIAVCLILVAIVGLVRYQSSSATPFSPSSLSSSSSSPSSSSPTMSVVHTVLFQFSADADPEKVKETCRHFISLKAACVSATTSQPYILSIKGGKDNSPEGLQGGITHGFVVEFASAADRDYYVKTDPAHQAFVKSLDGLVTKAVVVDFSNGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z891</accession>
    <name>A0ABR3Z891_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="415" mass="45108" checksum="DAFCD01E9EDCD3A9" modified="2025-10-08" version="1">MPLSAETLTNLRGIVDAACADPTTDIPGATVVVVDKSGNELFAHAAGKRGVVSSEAMTVEHVYWIASCTKMLTGVAVMQLVEQGVLRLDDGAQIAQLVPELTNLTVLKKDGTTEPQKKAITLRMLLTHTAGFGYSFFNERLRDWGFPAGIDEFTGRFEDIKTPLLFQPGEGWEYGVNIDWAGVALERATGLSLNEYMQKHILQPLGLGNMNMIPTAEMRAKLAYCHFRQPDGVLRHRNHLQRAPLVVDLNSKEEIARIFSSGGAGMFAKPGEYAKVLAVLLNDGTCPRTGAKILSKATVDEMFKNQIPQFPNSSRQPIPAAMPELTNPVGELYPTAGNPPQGWGLTFMLANSDGTGRSANTVHWAGLINAWWWCDRDNGVAGIVCTQILPFADMKVLGLWVGVEAEVYKGLAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8U4</accession>
    <name>A0ABR3Z8U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S26 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S26 family. IMP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052064">
        <property type="entry name" value="Mito_IMP1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383:SF16">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383">
        <property type="entry name" value="PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="7">
        <location>
            <begin position="23"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="7">
        <location>
            <begin position="114"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="166" mass="18118" checksum="03865EA1D9F71501" modified="2025-10-08" version="1">MSFFSGFSRAFYGHPGRWAIGTAKTLAFCHIVWTYGYSVGPASGPSMLPTFSVAGDWLLVAKRFRGGRDVRVGDLVVYRIPVEPSDEAVKRVMGMPGDYVLVNSPEGQSDLMIQVPQGHCFLVGDNLPASRDSRTFGPVPLGLVRGKVIAKTWEWIENPMDAEAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z904</accession>
    <name>A0ABR3Z904_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LAT1</name>
        <name evidence="10" type="ORF">Sste5346_004363</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="35"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="182"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="130"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="469" mass="49209" checksum="371F1A13C2F69396" modified="2025-10-08" version="1">MLAPVLRRRVFQQRTVLRYAVPSALARFYASYPPHTVVKMPALSPTMTAGNIGAWQKKPGDAIAPGDVLVEIETDKAQMDFEYQEEGVLAKILKQTGDKDIAVGNPIAILVEEGGDVSAFEGFTLADAGGDAAPAASESKEAAPAESAPTPAPSPSESAAPAEPEDTSSTGRLQTALDREPNIGAAAKRLAIEKGVKLDGVKGSGPGGKITEADVQKAASSGSSASSGAVSAASGAAYEDIPLSGMRKTIANRLTESWNTNPHYFVSASLSVSKLQKLRQALNSTADGRYKLSVNDFLIKAIGVASRKVPQANSSWREGAIRQFNTVDVSVAVATPNGLITPIVKSVESKGLESISNSVKELAKRARDGKLKPEEYQGGSISISNMGMNPAVERFTAVVNPPQAAILAIGTTKKVAIPAENEDGSVGVEWDDQIVVTASFDHKVVDGAVGAEWIRELKQVVENPLELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9J9</accession>
    <name>A0ABR3Z9J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF2">
        <property type="entry name" value="DUF1446 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11420)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="21"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="525"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="635" mass="69326" checksum="AA6A0EC766E274A9" modified="2025-10-08" version="1">MGSAGEVNAANGASGTPKRPIRIAGCSGGVYDRKRAIHDMAKFEDVDVITGDWMSECNMTLRGSDKRDRLAQKAMTSGSTEVAKGYEPYFLEEIDPAIPWLAKKGTKIAVNAGASDVHGLAEAVKALIKKHGVDLKVGVVDGDDVTDAVLDLYKKGEPFLNLPANKPISEWGFDPICAQCYLGGTGIAACFEGGADIVLCGRVADASVTVGAAMWWHGWTRENISELAGALMVGHIIECSTYATGGYYSGFKDLGTNDLDMGYPIAAVDHKGEAVISMEKDRDGLVNIETVASQLLYEIQGPLYYNSDVTASIEDIVLKQIGKNEVHVSGVKGLPPPPTTKVGITAKGGTQAEFHFYLTGLDIEEKAAMIERQTKARMGEYLDKFSCLKFMIAGHVPANPATQEEATVDMRIFAQTRDPHLLAGSSFVDSDRGSFARFCIENLLQSYPGGTMAPDMRTAIGRPFFEYWVSLMPQTFVHETAHLPDGKVIDIPAPTVTQEYPREQPSYDTVDPVDLSQFGPTTKAPLGYIALGRSGDKSSNCNLGLFVRRDDEWEWLRTVLSTGKLRELLGKDDVGRQIDRCEFPNIKAVHFLLKDHLDRGFNSTSSFDSLGKNLCEYIRCKYVDIPDKFLARGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB29</accession>
    <name>A0ABR3ZB29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057720">
        <property type="entry name" value="RRM_YTH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25701">
        <property type="entry name" value="RRM_YTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="494"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="758"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="793" mass="84382" checksum="28B6F5975801F1F9" modified="2025-10-08" version="1">MADQTSPREPPPAPAEARQQEQQQPKQNQQNQQQSTPIHSPTSPTSTFHQHAPQQYYSPPYQNPQDPRHPQHPHPQQFAPSNMQQPYYRPQGPGGGPHHHGPYDMHGMAQSLPQTDYRQQQQYSGSGNRGGPLGYTLGPGAPSSATGHPGPQYATHTGGMQQAFYMPPQLPMMGQPYYGSGPARYGGSGGGSYSYYGNHAPTPTGYYYPQQGQYTHHQQPQQQQQQHQHQQHQPKHQQGGMPGGSKPGSGAPGNYAPSTYTPRLSSQPMVVTGNPQADVIDGSPKPDQHQRSHPGQAQTQTTSVVRGPPRKPKQSGHAIWIGNLPPQTNLMSLVHHVCQQTDGLESLFLISKSNCAFANYPDEDRCLAAQQKLNDTWYMSVRLVSRLRKNAVEGAPGITAPTGPTALSMSSTASSLSQTDGDMAVDGTDGNSANTATADDTATTDTPATPTKPTPQTSVIVDGSGKSGATRRTTGYEAERAAAAAATPATAKSDRYFILKSLTVEDLDLSVRTGIWATQSHNEETLNDAFKSYENVYLVFSANKSGEYFGYARMTSEINQDPAAAIAFAPAAQTFTGVDLPKAIPTEATKTTPRGRIIDDSARGTIFWEAQRDDVDGEAEGTNTKQEEDTTDGVDGRDGVDGTGGVDGTDGVDGTDGVNGTDVVDGPDGVDGTDGTDGTDGVDGVGGTDGADGTDGVDGADEPKAWGKPFQLEWLSTARLPFYRTRGMRNPLNSNREIKIARDGTEVDPAIGRKLVSFFHQGNSSSPAASGSSGGRTTMQTSTGHSPSIGSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBC9</accession>
    <name>A0ABR3ZBC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF5">
        <property type="entry name" value="GENERAL AMIDASE-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="96"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="557" mass="60230" checksum="72F5DD1EAD74B5C3" modified="2025-10-08" version="1">MSSTVTTTATATEAVPLPTKSWQSIVEAKQAEQLSRIPEEWRLTKEMYPAEGTVDLRPVISTCGILTERELSITGDKYDATSLAAEIAKGTYTATETITAFCKRAAVGQQLCSFMTEIRFAEAIEKAKKLDEHFQATGKTVGPLHGLAMTFKECFHIKGYDACNGYVSRCFDKSTTTTPVIQLVEDAGAIVIGKTNIPQTMLVAECHNNVFGHTKNPIVSNLSCGGSSGGEGSIAAWRGSSIGVGTDVGGSIRLPAAFNAVYGYKPSVGVLPFIGYAPSGWSGVNSGIPAVLGPLGQSMRDMKLFTEVVRAQQPWKFDPAVIPGIMEGPLDKTKKPVVGILYESGITPHPPVRRILREAVAKIEAAGFEVRDFTPTCPDFKELRDIAAEMLTSDGLSYQTRELAKSGEPAVPSVVNFGYWGNRRQEHEEVWALNTRKGAIQKKMLDAWQALGIDILIAPSAPHTPITSDRTTSELYTVAWNAMDYPAIIVPFGHADKAQDVPDTEFTPKNDLDANIHTWYDADLMHGSPTSIQLVGPRLGDAALLHHAELLDAVLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBE0</accession>
    <name>A0ABR3ZBE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Arf guanine nucleotide exchange factor sbh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SBH1</name>
        <name evidence="12" type="ORF">Sste5346_004107</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="115" mass="11830" checksum="8CB540CA69CAB9FB" modified="2025-10-08" version="1">MSSPRASSPTPAGAASGASINRASSSSPPPPPGGARTQIRRRAAADQKEKVANTRPTSTRAAGAGGSSSTMLRLYTDESPGLKVDPVVVLVLSLVFIFSVVALHIIAKITRRFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC32</accession>
    <name>A0ABR3ZC32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="65328" checksum="A0F58486FDB23BB5" modified="2025-10-08" version="1">MADVEKSVQGVDAITPAHHEQQHEATYNDSSDEHEAIGGARFDVDEDELPPGYFKSRFFLGTMLAIGLGLTGGVAGFGYAAPILGTINNDIGPSPNIDWVALVYTLTSSVTLTIIGRVTDIFGRRWVFTGGTFLGIIGSVVCATAKNVNTLIGGMTIIGISAATQLSYYYVMGELVPMKYRFLGNAYVYMWQFPSSAFAPAVSNSFIQYTSVGWRGPFYVLIGVNSASFLCWFFFYHPPTFNMKHQNERMVTYLKEFDYVGTVLFSGGLLILMMGLNWGGSLYPWKSAAVICTIVIGAVSLVAFLCWETFMNLKEPLVPVHLFRNRGWNAATVLSGVAASMYYAYAIIWPSLCGLMWAREDDPMYAPWLSTFVGMFIVTGEIVGGALASRIRYLKWQCLGSAMLGGIFFAVVATCNPDTKVRACVLVSLGVFFLGWVESLSISLITLTAKDQANLGTSGGLAGSIRFFISCISSTIYTVVLRARSAVTIPAAVTPAVEQAGLPASSVPAFINGFTTGSFANITGLTTEILAIGTKAYYVGNFDAYRTVFLVTLAFTGMAFIAGILLPNDIDKYLTNRVHVTLHQGQDESVLAGEKREKRVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDM6</accession>
    <name>A0ABR3ZDM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="167" mass="18433" checksum="7A8E36DBF55136E1" modified="2025-10-08" version="1">MSSSKRIAKEFAKCSANAPAGMTIEMPYPDDMSIWHITLKGPAATIYAKGNFGLVVTLPDNYPFKAPVVTFATRIYHPNVTNDSAGNICLAMLKTDNWKPALPMTEVLEAVRNLLVEPQPDDPLEARIADEYRTQREEFDKQALAYVEKYAKGAPKFPPRGEAGSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEJ3</accession>
    <name>A0ABR3ZEJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF20">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="38"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="421" mass="46410" checksum="FFDEE3D93F04AF61" modified="2025-10-08" version="1">MGSVPTSASHFAALPTAPRDEIFALLGEFRRDTHPQRVNLGAGVYCDNDGEPFPLDVVRTVEKSMNEKADPHRHDYTPIEGDQEFLALARKFVFGDACDESRLTSVQTVSGSGANHVGARFLANTIRPRRVWLSAPTWANHELIWATVGVPVHFYPYYNAETRALDFAAMVETLEKEAEANDVIVLHACAHNPTGLDPTKEQWIVLGELCQRKGIFPFFDNAYQGFASGDPSIDAWAIRHFAQLQPPIEMCVAQSFSKNLGLYGHRAGAFHVVATGEGCTPAAKDAVTANLAQIIRSEYSVSPRYGSDIVKAVLGNKDLTRKWQAELHTMAGRIIAMRVCLYEELRRLGTPGSWTHIIDQIGMFSYTGLTPPEVTYLKEKFHIYIHSSGRISIAGLNTKNVKYVAAAIHAVRSDPSLVTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZER7</accession>
    <name>A0ABR3ZER7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF2B subunit epsilon</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GCD6</name>
        <name evidence="13" type="ORF">Sste5346_003038</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04197">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05787">
        <property type="entry name" value="LbH_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11558">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035543">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044123">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="12">
        <location>
            <begin position="631"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="545"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="831"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="832"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="856" mass="90778" checksum="BD0ACDEDA102ACB2" modified="2025-10-08" version="1">MSQANKKGAGARGKKAGGKGPADDKSEDVLQAVILADSFQDRFKPLTIDRPRCLLPLANTPLIEYTLEYLAMNGVQEVYLYCGAFADQVEGYLAASPRWSPTSKTNPFQSLDIIRVAQASSLGDFLRDLDKRGIIAGDFVLVHGDVVSNVPLDPILARHRARREANRDAVMTLVLREGGDSDASAGSSNNDHHTRAHGIEPIFVLDAATGRCLQYDEMTPLDHGDDRYLVIDPAFLEKNADIMIRSDLIDCSIDICTPDVLALWTESFDCELPRKNFLHNVLKDWELNGKLIYTEIVTDQPHTSGVGSTAGSYAARVNSLQMYDAVSRDILSRWTYPMVPDTNLLPGHSYATLRRRPGAGRGGAGVGVSAERSVTIDHTASVSRAAIGLYTTIGANSVVSGSTIGRRCRIGNNVRIENCYLWDDVVIGDNTVVTRSILASNVHVGSDSVVPAGSVLSFGVAVADKVQLNATAGNPVVLSVSKSNGSAVADDAAVVGAGGKGATYHHTTDDDDEDDEDSDAITAESLQRSLIYSTAHLNLSTSSISSFESDGEYDDEDAVFDDDDEEAGAEGGKSSGFLSASNAGGERGSRSRLPSFASLDGSRFSTSDGLAGRFASGAGGATGLIGADGVSTVSSSFHTDAVNGLLDALRDDASGDFESARLEFMGLRLSTDASDGAVRRAVAAAFARRACELAAPVDTPGEQGQGLDASKAAERAVKSKTGAAKFVRDVGVGNGTSDEQVEFVLALQRTLVGMRIREEKENKGKQIEGLAAPGTLLAALLQQLYDSDVLDEEGILAWWADGRAAEGGSGASGDSSMAGTRERCRVLVEWLETAEEDDSDEDDDDDDEEESDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEU4</accession>
    <name>A0ABR3ZEU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Chorismate synthase</fullName>
            <ecNumber evidence="3 8">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARO2</name>
        <name evidence="10" type="ORF">Sste5346_003306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="827" mass="90309" checksum="5483E32EE9F4A3B8" modified="2025-10-08" version="1">MSTFGEYFRVTTYGESHCRSVGCIVDGCPPGMQLTEEDIQPQMDRRRPGQSSITTPRNEADRVEIQSGTEFGVTLGTPIGLRVMNKDQRPKDYGNSTMDLYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLRLAYGIEIVAFVSSVGKVHLFPPGCEDDTASAEAAALNELLTKIDRATVDKYAPVRCPDEKVAAEMATNIEGFKEREDSIGGTVTCVIRNAPPGLGEPCFDKLEAVLAHAMLSIPATKGFEIGSGFAGCEIPGSIHNDAFVPNEPLPAGTATPPGAAATRSRLTTKTNYSGGVQGGISNGAPIYFRLGFKPPATIGKEQTTSTYDGTAQGVLAAKGRHDPCVVPRAVPIVEAMAALVIMDAVLAQQARHTSRQFLPPLSQTLPVAPPADNGVTEEVKNVTNIDHVPSVPSISAAASAAASPHPSQTDTTPPTVAASTPQSQPQSLYDHRDHHDHSSRDTPAPLSDRDRDRDSIPPANMAQLELVRNVYKTDLGLPYFKNMAAFKFRKIFLDLAAKTPFLMNALLAFSSRHMVETHPDQAAHYQRQALQLQTHALRMFNEERHEFKSPDTCIAVLFFSWLIGTHMLSDVQSSPNNSRQDTDAEIDSSKDADTDTGTLDRFIAYMQTYRGTRTITSTTWEVILATDMASIIHDGIKRLELVSEGPETAPLRTAVRAALAQEHARTGNTAEDMEESQAFDTAIARIQWVVDAYNQHEQDGTDYHEDLVKALSMWTLVIDKAIFARFIDKHPVALVILAHYAVILFWCRDVWLFGNVGALLLEDIARSIPAEWKTVLAWPMEVIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFE6</accession>
    <name>A0ABR3ZFE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">DNA-dependent ATPase protein rad54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RAD54</name>
        <name evidence="15" type="ORF">Sste5346_003027</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013967">
        <property type="entry name" value="Rad54_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08658">
        <property type="entry name" value="Rad54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="244"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="577"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1899105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="818" mass="92206" checksum="10CF33B16D838D13" modified="2025-10-08" version="1">MDCDRATVVPIPQGKPTAVGRHNNKENIPRGRFPPPKAFDALSKPFRCPGSSTASPASDRPARKRKRVDYKGADGGEDGDKPYTNEDRLALATREANKFPVFRVLDKEQAFRKVFVVPLINKSTAAYNPSRPAPALGMRQGRAFVAKPLHDPAGEFSIVLYDPTIDDKPKEKTPEEIEAEKAKVEAPKVEVPLVHKSLAEILGIKKQVQEENPRVPVVIDPKLAKILRPHQIEGVKFMYKCVTGMIDEKANGCIMADEMGLGKTLQCITLLWTLLKQAPEAGKTTIQKAIVACPSSMVRSWADELDKWLGKGTINPFTIDGKASKEELSRQLRQWAIASGRAVTRPVIIVSYETLRLNVDELKNTKIGLMLCDEGHRLKNGDSRTFNALDSLQVSRRIILSGTPIQNDLSEYFSLVSFANPNLLGNRLEFRKQYEIPILRGRDADADEEDRKRGDERLAELLNIVNRFIIRRTNDILSKYLPVKYEHVVFCNPAPFQLDLYNYFITTPHIQALLRGKGSQPLKAINILKKLCNHPDLLDLSTELPGSERCYPEDYVPKEARGRDREIRSWYSGKMQVLDRMLARIRADTNDKIVLISNYTSTLDLFQKLCHHRGYGNLRLDGTMNVNKRKKLVDKFNDPNSDEFVFLLSSKAGGCGINLIGANRLVLFDPDWNPAADQQALARVWRDGQKKDCFVYRFITTGTIEEKIFQRQSHKQSLSTCVVDSAEDVERHFSLDGLKELFQFRGGGATTSDTHDTLKCKRCRPDGKQFIKAPAMLYGDTSTWNHFVNAGLSQIQDLLLRQECGDEVVSAVFQYISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFN7</accession>
    <name>A0ABR3ZFN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF11">
        <property type="entry name" value="METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="59641" checksum="D6066E9652E63328" modified="2025-10-08" version="1">MLNRSALALVLGVVGIVTTSAVFLSADAVVSPSQAARRASRAACDPTAPLQFHSDGSFQISIFEDLHFGENAWTHWGPQQDRNTVRVMGDVLDAERPSLVVLNGDLITGENAFRENSTVYLDQIVAPMVHRAIPWASTYGNHDSDFNLSRVDLLAREQQQVPTGLARTTNMLPTPKHGDTRRAGVTNYYLPVYGSDCASTNDKDMVDNCVPKLILWFFDSRGGFHYQQKDATTGKRVGQENWVDDSVVSWFERTQAELESKYASAIPSLAFVHIPPNVAYALQMNASPDGKASGRSSNIDPHRQPGINDDKPLAQQAEGWCPSGLQGGCAYGGQDESFVRAIAASGNGTGVVAMFVGHDHGDTWCHTWASGRMLPGVDIPGTGVHICFGQHTGYGGYGSWTRGGRQVRVTEESLRRAAAAASPADRRPAIETWIRLEMGNIVGGVSLNATYGHDVYPATPNTHTHCPTCGSASVAPGMVSEQNRPSFWRDWSRWGSVSGLDSKKSSRSGTVDKVGQSAEAAGDIQSPKLQVQHAHRQKQGLRRYLSWPGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGD8</accession>
    <name>A0ABR3ZGD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhomboid protease</fullName>
            <ecNumber evidence="4">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RBD2</name>
        <name evidence="13" type="ORF">Sste5346_003048</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="88"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="294" mass="32070" checksum="A4E9F6D90EA72097" modified="2025-10-08" version="1">MPSPSPQPRRSGIADLWTPRGSSSSASASPAMAAFNPARSTRSYLARLPLFTRVVAGLIVALYLLDWLPFWDLRAWGGLVPSKLSFATLYRTNTFPLIHISLFHMVANVVALVPLMDRFECEHGTITTLALFFGPFSTLPALIYVFFERIFRMDTTVMGASIWVFLLLGVEAIRTYRQNPNLIVASVPVPTWATPLFFVFVIAVFVPNTSLPGHLAGLGVGYLCGLGYLKFLSPPESALRWIEARLNLLARVPHYVSVDQKTYGRFGVLPSVSTGATGAAPAIGLVGSTQRLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH78</accession>
    <name>A0ABR3ZH78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="741" mass="84132" checksum="ABA5AA54513DAE0E" modified="2025-10-08" version="1">MAALSLSRLGSPMGKMGRGRSWTGFARPRKTMYLLLSVVVVYFLMASWSNIRHLASALRKTDLIKDGKGIGVVLRLGGVEIQGLDNNIFDESQLPFDDVNVTQRKSDDEIRQEFDREYSEAGKQPGAGKLYGGTLSNLVLPDDAKKSNTAVKLTKWKTAPSFSSEKPYKVDPYPNYNSWSWRRSGKARYVPCKGPLDRPVEDVSAFLGLPSGFPSPSIGGYNLFDIDQNLCYERDTRLGIYTLPDGTRDTIDWGDVQINCVDRNQARFDLVGPPNELVTTAYGVLPGAESSSSSNQNHKLRRSSSDSRDDTTNDGESERKLSKIVHEQRTAILLRSYTGKKYTENDRYIIRSLVSELNLRSGGEYQVFLLVHVKDENVNLWDNQTYEKYLQESVPKEFIGMTLLWNDDFVQETYPKLEKNWEASVHNAQWLSVQKFMQEFREFSFVWNWEMDARITGHAYDMLEKIGQFARRQPRRGLWERNERYYIPEFHGGYDTEFRESVEAMSKKNPVWGPPKDTPFINPIGPRPPTASPQDDKFKWGAGEDADLITLSPLFDPKDSGWVLGGQVWSYNDDKHSSESLPRRGAIVTQCRLSRRLLDIMHVEDLRGNHVGSEMAPGTVALLHGLKAVYAPMPIFMDRPWAPERLARWFNNGPRGGSSGGPDSAMGWGREGRFRGTTWYYRAEPPQRMYSNWVGYEDNGVGGLEWEMAHGRPCLPAMFLHPVKDVVPTSPGYGSESRLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ7</accession>
    <name>A0ABR3ZHZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette transporter snq2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SNQ2_1</name>
        <name evidence="12" type="ORF">Sste5346_002688</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="648"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="681"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="740"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="820"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1269"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1298"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1338"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1376"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1412"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1530"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="204"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="891"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1556" mass="172700" checksum="F970B69A1E7744B9" modified="2025-10-08" version="1">MAEKDLEQGSAPVAAPVAAAPTEATTPATASQSDPRYEHGKDEVEIAPRPSVSSTSTATTVDLDNLREEARRNNPNGTTRPDPGVSVENAVNEFEHLQHELSGMSRASRVRSRAESRVSHTRIPLDAEKAVAVGKSSDGADGDDNGDESSEDRFDLESYLRGSLAAERAAGIRPKHIGVYWDQFSVRGMGGTSNYVRTFPDAIVSFFDVISPMLRWMGRGPKGTQKTILENFRGVCKPGEMVLVLGKPGSGCTTFLKTIANQRYGYTGVDGDVTYGPFTAKEFEDYRGECVYNQEDDVHHATLTVEQTLAFALDTKIAGKLPEGMTKAKFKAEVVDTMLKMFNIEHTRNTVVGGPFVRGVSGGEKKRVSIAEMLCTNACVVSFDNSTRGLDASTALDFIKCLRAYCSLYQTTTFVSLYQASENIFSQFDKVLVIDGGRQAYFGPAQEARGYFESLGFEARPRQTTPDYLTGCTDEYERIYAPGYSEENAPHDPASLAEAFDKSAFNARLGEEMAAYKATLPEEEEKYHDFRLAVKESKQWGAGGTVYAIPFYRQIWALIKRQFVLKWQDKVALTLAWFRTVVIAIVLATLYLRLPVTTESAFGKGGLMFISLLFNAFEAFAELSTIMLGRGVLNKHRAYAFHRPSALWLAQIIVDQAFAVTRIFVFCVIVYFASNLYRSPGAFFTFFLLILSGNIAMTLFVRIVGCISPDFDYANKMAVVMVTLYVITSGYLIQYQSEKVWLRWIYYINILGLVFSAMMENEFSRITMTCSPETLVPSGAGYNDINHQVCTLAGSVYGTDLVSGTAYIEQGFSYSPNDLWRNWGIVFAIIVFFLFLNVVLGEIVRFGMGGNAALVYSRPSKERTDLNKKLLEKRDERRRTKEEAASSELSINSKSVLTWEGLNYDVPVAGGTRRLLNDVYGYVKPGSLTALMGASGAGKTTLLDVLASRKNIGVISPSRSVLVDGQKPGKQFQRSTSYAEQMDVHDPSQTVREAFRFSADLRQPYETPRAEKYAYVEEIIGLLELEELADCIIGLPEAGLTVEQRKRVTIGVELAAKPEMLLFLDEPTSGLDSQSAYNIIRFLRKLAAAGQAILCTIHQPNAALFDQFDRLLLLRSGGRCIYFGDIGKDADILRAYFKRNGAVAKDTDNVAEFMLEAIGAGSSPRIGNRDWADLWAESPEFVDVKASIEQIKAERIEAVRLEEMEASGVLGGSDNLALEQVKSAATGTGIKAVAPQKEYASPFVHQVRIVVHRTSVALFREANYQFSRLFNHVVIALLTGLTYLNLDDSRSSLQYKVFVMFQVTVLPALIISPVEVMYHIKRSIFFRESSSKMYSGPVFALGMLLAELPYAIICAVAFFLPLYYMPGLQKETSRAGLQFFFVLITELFSITLGQGLASLTPSTFISSQFDPFIMITFALFCGVTISSANMPAFWRSWLYQLDPFTRLIGGMVVTALHDLPVVCKEAELNVFQPPSNMTCEDYMEPFFSRGGAGYIANPSSMSDCGYCAYKVGDQFYEPLNLSFDNRWRDLGIYISFIASNVIIIFLASRFLNFNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIT1</accession>
    <name>A0ABR3ZIT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPP0</name>
        <name evidence="7" type="ORF">Sste5346_002331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="6">
        <location>
            <begin position="109"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="312" mass="33437" checksum="4DAE2C6F2E5281B6" modified="2025-10-08" version="1">MGGKSANKAGYFDKLKGLLESYQSIFIVGVDNVSSQQMHEIRQSLRGEGIVLMGKNTMVRRALKTFVVDTPEYERLLPFVKGNIGFVFTNGDLKEIRDKILVNKVAAPARAGAIAPIDVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEGGSKVGPSEATLLNMLNISPFTYGMGIEQVYDQGNTFPPEVLDIGEEQLLGAFSSAVTTIACVSLAINFPTLPSVMHSLVNSYKKVLAVAIETEISWPEIEDLKDRIANPEAYAAAAPVAAAEETKAEAAEEKAEEEDEESGSDGGFGGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIV2</accession>
    <name>A0ABR3ZIV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SMC3</name>
        <name evidence="12" type="ORF">Sste5346_002862</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03272">
        <property type="entry name" value="ABC_SMC3_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041741">
        <property type="entry name" value="SMC3_ABC_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="11">
        <location>
            <begin position="522"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1048"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="399"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="674"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="851"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1210" mass="138126" checksum="0505AA26D4F5232F" modified="2025-10-08" version="1">MYIKQLIIQGFKSYKDQTVMEPFSPGTNVIVGRNGSGKSNFFAAIRFVLGDAYTQLSREERQALLHEGSGSAVLSAYVEIIFDNSDNRFQTNNREVSLRRTISLRKDEYAVDKKVSTRSEVMSMLDTAGFSLKNSYYIVPQGRVTALTNMKESDRLKLLKEVAGTESYEARRAESLKIMGETENKRAKIDELLEYIRSRMSELEEEKEELRGFQEKDRERRCLEYAFHHHHQVALTEALEEIDRSRQDGADNSGASQKLFLDGENAIIRIDNELQELQRSVDILNMDRQEFELECRDISRSKAKAELKVKSLADSQNAVDRAKKQHDAELKAVRTEIATKESQLARILPDLEKRRAAEAESRQALHSADARRQRLLNKQSQGDRFKNKSDRDRWIDGQLAELNSTLAALRANRVSAAEETEEAKRLIQSLENEIDELWKGIESFGSDRTALSDKLSKAQDRVQKLDDERRALRREDDKLNTHISNARQERDKANRTLSNMMDNATARGLATIDRMKREKDIPGAYGMLADLMEVNEAYRIPTEVIAGNSLFHYVVDNEETSTLLSNTLYRQQGGRITFIPLEQLRPRQANFPQGAKDALPLVDKIQYDKKFEKAIQHVFGSTVVCPTVSVAAQYGRSHGVDGITPEGDTTKRTGTMTGGYVDPSRSRLEAIRSVNKWRSEHDNLVAQADDVKRQMDRKEQEVTNARGEEQKILHQMRQLEEGFGPSRAELSAKRAQLERERARQDTLGQRYENINKSMEEYATSLESHEAERKSEFKKALSTAEEQQLDRLNNEVQALQRQVNEASSRRREIEGQKQILDVDLRQNLRMKEDQLTSQVFETMTSVGGDGNYAEAQKELKKLQKRLDEKETRLRETLNEMDEQQAEISDLQANKVDLERKQQEIATSLEKSQKRMEKSLQRRALLTQQLAEAAKNIRELGVLPEEAFEKYEQMDPAKISKRLKTVLETLKKYRHVNKKAFEQYNSFTNQQEQLLKRREELDASQASIEELVAHLDRVKDESIERTFKQISKEFATIFERLVPAGHGRLVIQRRDGRQQEENGDDDEDDVAGGSSALRRQRRSVESYTGVGISVSFNSKHMDEQQKVQQLSGGQKSLCALCLVFAIQQTDPSPMVVFDEVDANLDAQYRTAVASLLSSISKDAGTQFICTTFRPEIVQVADKCYGVTFTNKTSSIGCVTTEEALNFVDGQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIZ4</accession>
    <name>A0ABR3ZIZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002356</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF163">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_8G05510)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="31"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="418" mass="44948" checksum="EECEB722C3571D11" modified="2025-10-08" version="1">MGLTSGEDYNRNLTIGVVTTCLILSVVSFVFRLFARTRSAAKLWYDDYWMCFVMVLCFAMSACDYTGLKFGSGQHQADLPVDEFTSFLKNLYVYMILWACGVFAVKVGILLFYWRVFPTRSFRVGVIGVSCLSTGIFLGNFFSFALQCLPVALFWDESVDGKCINRNAFYLASAIINVLGDVAVLFLPIPVVWGLHTSRSKKFSLSFLFLLGAFVCVASIFRILAVKEIDPTDFTFSNVGGGLWSTVEVEIGFICANLPALRPLFARWFGHGGGSSAGQSGYGAYGSGARNGGGGGGASGYGMHSKISASRSGRMPLGSKNGDRDVELMSQGNSSDEINLTKGGRPGTSGSDGMGSDSNTPHGQSHGMPSRVTNVSHGVGSNAYGASGIRVKTEVQMTVDEWSQPVDKKRGDSFPLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK20</accession>
    <name>A0ABR3ZK20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF4">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="206"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="775"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="835"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="879"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="957"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="206"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="778"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="852"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="891"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="962"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1029" mass="112977" checksum="EE86ABD4FE44E947" modified="2025-10-08" version="1">MDTMRAPKRAHEDDGASGVPSEAGAHASPARSKLAKLDSTSSTSSNSKSFASDDFSSVVKNKLSSYTRTGQACDRCKVRKIRCDALPEGCSHCLGQNLECYVTDRISGRTERRGYLQELEREKTAMARHIEQLQTLLAERGGVEVLPWRWSPYAPVYPPGVVLDGQGRVVEVKGDDGESVDSGEGSDGPQEKRQWTCMGSVWWRPSKNANSSNTATTSLVTTTTGRASSTTASLSTPNTPTYTYTPTPSSPSSALQSCPVDSYLGVYADRAPLNSVNGTQVSILGTLLDIDAADTGIEPEPSAIYREPTGLYNRSLGSFLRSAMNINPSLDSSIELPSRSDAFEYSEWYFLMVHPFAPILHKPTYLALLTRIYDDPKFTPTTSELVIVHMVFAAIYFQYGVRNREELTRQIHLHDLSNKHYHWALSKFYYIASDFSVTAVQALVLITLYTRAFPKPSCGSTIAMLALTKAINLGLHRSAGIPAARTTLTNEMRKRAWWGALMLAATLNGRLGRPMPIRVEDFDTELPVAIGDEYLTEQGITDPSMIGKASFLVGLHAFQFTPLYMEMFSHLYGVRRDPRRYAPLVRDLEAQYRNIQARLPAELHVDKCKPASLMYALYAQAVSLEFLLCLHHPSACMTTDPQVFAENTRICEETARTLLKHVQKLLELKSLDTTWYQMSVYCAAMFSTLAAAWERRKTVTAAEMERLQDETSIWLSIIAEIGLLTGASENGQPFNRKLTQICARTIFGILRDMPAGARNAVMAHNARAIQGRGIPINGQAQLPGSSSATNPSQTASVHADHNINNGRRSPPGNIDSVALHLETQARLKLEGRGQLSPVTAPQQQQQPPPQQQHPSQFHQPSMQMPTTTEEFVMTSPFPQQQQTMNGAGYDQQTQHQQPPQGQPAHSQQPLMSFTPSALGAPANPWTNWTASIADSQRPNDDRFTSADALLDLSMLHQRLAPGPGPGPGPAPSPLGVTDGNEPATADNGLPTMMVPVGPVNTLGQQQQQQQAQQTSVGTHSAQWPLILFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKP1</accession>
    <name>A0ABR3ZKP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002059</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="100"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="383" mass="42757" checksum="40DBEDC9F9B6C015" modified="2025-10-08" version="1">MAPSAIETITVPEPSPAELQLHTTTAAAGDYKELSPTRFSKEDEVTGIDGFEAAKYPNYLPTWNPDEHYPPLVPFEHYEHGKDADTTFPELIPESATRVDLTPTIGSEISGVQLSSLSNAGKDQLARFVAERKVVAFRKQDFADLPIQEALDFGAYFGRHHIHPTSGAPAGYPEIHLVHRAAGDTTAEKFFATRTNSVAWHSDVSYELQPPGTTFLYILDKPETGGDTLFTDAVEAYNRLSPEFQKRLHGLKATHSGIEQVNSSVARGSIKRRDPVYNVHPIVRTHPGTGQKALYVNPQFTREIVGFKKEESDALLDFLYNHLALGADFQTRVKWEEGTVVVWDNRVTQHTALVDWKGGARRHLARITPQAERPFETPFEEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKU6</accession>
    <name>A0ABR3ZKU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="253"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="41233" checksum="8D09F1D878B1CC36" modified="2025-10-08" version="1">MAEEQPDTHALRAAINAMRRLRTNKTPDPAAFETAQAIPLLVLAVELHHHDAIGVLLTYRTTLPPQLRDPPQREDRGECGIAGTPLITTCAMGFLDTLRLLSQGMPCADLYEVDNNGFTPFLAAAAGRHGPPAERLTFSVVYSSAALTSAMFYDEDEEDDEDLDEFRPRLNGYGNTLALAMEYPDIDPTVLALLVEAGVDIYQSRAETVDRIDKTNNHTDNYTALVRKDRGLSPVAISPSTEYTATINAPYRHHHTPLHMATDFDRIPMLLALIELGADLDVPRHDGRGLVLALFSSVPRLSPIPYNDVTAWAVAVDESTDMTTVLTTLLQRYRPLGHDADVDARNAAARDAIVNEADANGNTPLHFAMAYRLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL42</accession>
    <name>A0ABR3ZL42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NRC2</name>
        <name evidence="10" type="ORF">Sste5346_001853</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="346"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="725" mass="77679" checksum="4079F857847EE745" modified="2025-10-08" version="1">MPSLNAKSVIGGITNSNSTNSNSNNSNSNSNSSSSGNGNSHFPQKLKNFFRINNSSDSNNSGSGGHHEKSEKPGVLSLRTDSSGNTGSGSNGHHGNGTGKTGGFRQSKFFSVGRLRSQTVASEGNILEESLSPTALANPYFAHQGQPGIRHHNEGSQPPSPPDTPSLKVLAANGAGSPGAGQAANAAAAAANGERTTTASKEELARKLRRVASAPNAQGLFNKGAAAANAVANGGPLPNNGFIVGGKDSDERPQTAELGKEPVVMMKNSSGLSLVDAKKMAAGFHSLSSSPALVNDIASGSAGGIVVDKDVLGALPPPGRSPLAFRRTYSSNSIKVRDVEVGPQSFDKIKLIGKGDVGKVYLVREKKSSRLYAMKVLSKKEMIKRNKIKRALAEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCSGGEFFRALQTRPGKCIPEDDARFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKQSDTGGKPTMIIGKNGASTSSLPTIDTKSCIANFRTNSFVGTEEYIAPEVIKGSGHTSAVDWWTLGILIYEMLYGTTPFKGKNRNATFANILREEIPFPDHAGAPQISNLCKSLIRKLLIKDENRRLGARAGASDIKGHPFFRTTQWALIRHMKPPIVPNQGKAIDTLNFRNVKESESVDISGSRPMKLKGVPLDSGLSTPGNEIVVDPFEEFNSVTLHHDGDDEHSYDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMC5</accession>
    <name>A0ABR3ZMC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="587" mass="63231" checksum="CB3BCA020476D595" modified="2025-10-08" version="1">MTNMLRKKELVTIITPIPGFIPRQLAIDILHSHSEVITLNPLVLDHKPIKAPRDAASDEYYSTWYEITERIQYVPGIGKMGSGKLAFNACFHDMPWGLQAHIYAPMNTDLRYKYRIAGNQPGIEPPETLEMGLASLGAPSDGLYLREDVEVKCSIAVMSFVKSQLKAASKLMVQRIIKKAELVDSGVLTAMIENGRLKTINPADRSYTLNAAAANNGGAGSASSPATTSTSPAIPNVDRDSKTPQSQQQGSPQARTETPGSPPPVPYQVPRPQSMQPQSTAAGALGGGGLQSPYGYRPGSAGVAQQYQQQPPGSPGLGIGVYSPYPGFPGQPGQPGQGNYSAHPGHASYAGPSGGGYYQQPMHPMYPQYTGQQPPYPGQNPYGQQQQQQQQQPQQFYAELQAYPQHQLPPQQHLATTGGQQPYTHVAVEMPGDYYHAQAAHQPPPNPYQQQQQPQQQAHTPGSTPQMNRDSDILAQGQWSTPNQPQAGSRPDSVASNNSASGGAPNSNGYRSPGLDKSFSSDLATHRETPEEHRLEALKKLDPTATPAALNISHHPSQQSQQPAQEQGKQAGYSYDGAEYGTPVQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN16</accession>
    <name>A0ABR3ZN16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_001873</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="59"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="168"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="40941" checksum="B7FB9E1344EDAE4D" modified="2025-10-08" version="1">MPTQGGSNSNNSSGGGTIASVQSSSSTFSSSSPSSSSASSSSLPLPTPAKSKEPPQRWVKRYRTEVSASLSSGISTACAFPLDSVKTRMQTYKYAGFIDCLKITYNQEGLRGFFRGVTAPLASVTIVRTISFSIYQRAKYVYSDWLSKNFGFDVLKHVNTPGTYPNLWSIACFGAAGATAGSCITVIACPFELTKLSAQVSVLLSEKTTCPDSQSRAVASSYQNKGTFKTMANIVRHRGFTGLYTGYKLHLLRDTLGTSLYFITYESSKQLLTTFAGDATKSSTVPVFIAGGLCGIVSWSLIYPIDSAKSIYQRNALLYSKGQKVKPVKIHFFQRQMYRGLGVSMSRSCVLNAIFFSSFEFWKKRIDKLEDKPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPF6</accession>
    <name>A0ABR3ZPF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Actin organization and endocytosis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PAN1</name>
        <name evidence="19" type="ORF">Sste5346_001028</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DUF1720"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF173">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08226">
        <property type="entry name" value="DUF1720"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="195"/>
            <end position="284"/>
        </location>
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        <location>
            <begin position="228"/>
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    </feature>
    <feature type="domain" description="EH" evidence="17">
        <location>
            <begin position="468"/>
            <end position="557"/>
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    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="501"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="298"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
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            <end position="652"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="771"/>
            <end position="881"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
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    </feature>
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            <begin position="16"/>
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            <begin position="1379"/>
            <end position="1441"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ21</accession>
    <name>A0ABR3ZQ21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EDC4-like protein pdc1 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_EDC4L"/>
    </dbReference>
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        <property type="entry name" value="EDC4-like"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EDC4-like protein pdc1 beta-propeller" evidence="7">
        <location>
            <begin position="608"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1111"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1203"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1491"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1583"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1137"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1171"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1206"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1222"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1501"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1512"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1536"/>
            <end position="1554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1817" mass="198234" checksum="82A6E20C9947599C" modified="2025-10-08" version="1">MSSEGGDDGQAPGPGIESLLAQLRRKSDQDSSPGHSHQANDLLSHFTSTIQHRPAADHYNYPPQQHAESSPNGSGPAYGNNGLPQAPSHFNPSLSSNLPSAPTPPVGGGFPNAQFPPSLLGSIGSGRPNNNDRATSSHLLNLLKFSGHANASQSSGLSQASNASQHNDSEPESAQQQQQQHTPKVALSSGMIHAPAPAPSDPTGLLAALMQGTLKDESSKPEPAASGNATQQTQQQQSAPWVSTSQSNETQQYLLNLLNRPKPSQNDESLSAESPKAARLTPTSSQQQQKDYGVYDDVAPSSTGSPATLAMPPSTNVFDYEIKGSEAGDENSPAPKPALFHQHNPFDGLVSSPPIGHTPKSSTTAGPGSIHSPAHSATSAPKPVQILRKPASNTGKKSKPSSAEPSPAGSPSISKGRPESSHKSNLAIRPLPPVVSEVTNEASDEGAGDSDAKYDQDAGDSDFKDDQDPDAETTRDSANQSSDDTKDETESTQEAVVREEIAMDLDDMEHAKTEEEFHAAAQAAGRAIQQELEREGGKGALDDSLPRDLADAVRDIVDEAAQGPVADSWESADAEGEEIVVVEELPVPVRVYNFPMRPFISIDVQDDDKDNRPIFRDESILDIARLKKDFDQIDRNLVAASENYMAYGMSKAGGLRVIRQTDGRDAKLFTDTKDRIFNVAMSFSNDEGVVTPKDSVIGTGVSGTVYWVQVRDGDKDHLDYAHPELYGFALPPILSHEGDAPGGVLKTRARTSSGHPEYFAVGRGKSINIVWPGFVMRNNLFQPGHDRVVDTEKLSKQCSLKISTGKAGKDFTFSQDDTVVVSLDKSGRVKFWDVRDLTASRPDGSRNPMPAHTSMEVKEPLLTLTTTPEGEKAWPTSVLLLDKLRPYQKRCALRYMIVGMKQNHTLQLWDLALGKPVQEFNLPHSKESDAVCSVMYHPPTGMIVVGHPTRNSVYFLHLSAPKYAVKNMSQVEYIERLTAQDSSIPQPESTAVISGLREYSLSNRGDLRSLDILENPAANADLNNPTLFELYAMHSKGVSCIFIHQAELGWTKDNKVLQPVDAVESGKVKIGKLKTPQQLAAPAAEIHIADANTPAAQQQPRIIASRSAAKELFQDRDSPVQDTPTRKPVVSSLNSKLRAEPRDEDAVGHPQPSSTPSADKAEKKSRKKKAAAAANNGTSSSSATAAAVAAGAAAVAAGAQTDREVNNATNGNNKSAASGDVSSKSAAGAQQAGASSSKGTLNVSQDAIDTRINTMEARICERVSSSVHVAFDDMRKSIDQQFRLRDTDFENKQRKLLDLVSNVLNSNTEQVLSKIVREEFDKSVVPVLRDDVARSISDSLGTRINTQVSTVLQKELQRILPAQVTSSLRSQEVSKAISDKVVHAIANHVDDQFSKVVESDLLPTVSSMSNQAAKTIMETISRDIAHHASETQALQQRTTVQINVLEQFQAAQSRKIDSLMSLVTHLTETVATMATAQSEYQSQVVKLQGQVTSPQVPAPQSIPQTGSAASYSSQPQQQQQQQQQQQRSPLQHHQHAPQPHQQLRAQQQQQQPHQHAPHQHGGYEGAVQQQQQQQQQPYRNITNRVGEGLSPSQHSNSSQQLQHQLQQQQLQLQQQQIQQQQHLQQQQIQQQQQQQLQQQQQQLREQQQQQHVLYAPQAQEDLEREEIEQIAVQIEGLIQSGKFDDAMMRWLQSNGKEEQLFRRVLVNHSPEIISNLQPLVLLSVGTTVTQDLDDHFAVQKLAWVEMVLLNLHQVVNQLDDQTREITPNVLMHIRARLEQTQIRIARVSHDEANYKNITRMIGIINRLVDATKPRLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ71</accession>
    <name>A0ABR3ZQ71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="5">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">INO1</name>
        <name evidence="9" type="ORF">Sste5346_000771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="8">
        <location>
            <begin position="335"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="58236" checksum="4FA56CEFB3A6C2B7" modified="2025-10-08" version="1">MAPHAEIDSSNGDGPTNGLNGQAAAAGNLFTVSSPNVVYTDSAIESKYTYRTTSVTAGPDGRFTATPKETLYDFKTERAVPKTGVMLVGWGGNNGSTVTAGIIANRRGLTWDTREGPRAANYYGSIVMGSTLKLGTDAETNRDVNIPFHDVLPMVHPNDLVIGGWDISSLNLAESMDRAAVLEPTLKQMVHKEMAAMVPLPSIYYPDFIAANQEDRADNVLPGSKAEWAHVEKLRADIREFKANNNLDKVIVLWTANTERFADIIEGVNDTADNLLAAIKAGHEEVAPSTVFAVASILENAPFINGSPQNTFVPGAIALAERHNAFVGGDDFKSGQTKMKSALVDFLINAGIRLTSIASYNHLGNNDGKNLSSQRQFRSKEISKSNVVDDMVEANSVLYKPGEKPDHTVVIKYMPAVGDNKRALDEYYAEIFMGGHQTISLFNVCEDSLLASPLIIDLVLIGEMMTRIQWRANGAAEYKSFHSVLSVLSYMLKAPLTPPGTPVVNALAKQRAALTNIFRACVGLEPESDMTLEHKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQD5</accession>
    <name>A0ABR3ZQD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07187">
        <property type="entry name" value="YvcK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="579" mass="60917" checksum="0B4F6084942E0D93" modified="2025-10-08" version="1">MDDGTGTPFRPAAVLATSIGLTASPGSASPMQTSAPTAAFTSTGETAAADTARNGVCVFSGGTAANSLVDAFHGVAKHLSTDNEAEETQQQKRKPPCALTYIIPISDNGGSSSELIRFFGGPSVGDVRSRLVRLIPSSDDEGNERAALRALFEHRLCSSDPNQARSEWLDLVEARHLLWTFVPSATRELIRAVLNTLNLEIVKRARPSTSVFNFAGASVGNLFLTGARLFSGSFEAGIYLLSLLCGIPDHVAVLPAINSNFTHHISAGLVDGTTIAGQVNISHPSLPTSLPDGGPLTVGATGGGGTDGTGEVDVAPDAGVPSGPVFRQDLKARKRASTAVDFEDATLPGSLPALRQPAIAFSKEDEEDLPSRIARIWYINPYGHEIRPQANPKALAALRQAEAIIYSIGSLYTSIIPSLVLRGVGAAISCIGNNGDPPRKKVLILNSKLDRETGPSNQAMTAVDFVRAIVAACKQSQSDFSPVQDSECLQYVTHLVFLDTAPHVGNLSSSAAPKVHEEALGQLGIRCLAVPTQASQEKQAAGEGAAVASKKAMERYDQAALTRTLKQLLDGTWEKAQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQI1</accession>
    <name>A0ABR3ZQI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NMD3</name>
        <name evidence="12" type="ORF">Sste5346_001316</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="257"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="323"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="476"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="539" mass="61037" checksum="25DD91F51EDDAA68" modified="2025-10-08" version="1">MSTMDLDDSVQVGNAPKTVATILCYNCGTPIDGTTAAGAICHECIKLTVDISKNIPREANIQFCRDCNRWMIPPTQWVSAEPESREMLAMCLKRLRGINKVRVVDARFIWTEPNSRRVRVEITVQDAIADGVLLNQSFEVMYVVSTHQCPDCAKSYTHNVWRATVQVRQKVTHKRTFLFLEQLMLKHGAHREALNISEAKEGLDFFFAHRNQAVKFVDFLKSVVPIHMTYSPELISEDIHSGTRSMKFAYSIEIVPICKDDLVALPLNMAKKIGGISPIALCHRIGTSVNLLDPTTLQTAEISAPVYWREKFPIAPLADVKELVEFVVLDIEPTGPRKGRWLPAEATVARASDLGSNDVTYFTRTHLGGLLKPGDSAMGYLLQGSNFNNPQFDEIEKSHSYSATIPEVVLVKKHYPNRRKNKHRNWKLKRMAKQESELLPKKADQARMENEYEMFLQDVEEDEELRAALALYKNPSQKAQLAAERRKRMAESGTMDVEEGEEDMEEDEDDEDDDAPRVNLDELLDDLDDLDINDDGEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQZ8</accession>
    <name>A0ABR3ZQZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptide hydrolase</fullName>
            <ecNumber evidence="15">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Sste5346_000360</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053976">
        <property type="entry name" value="PFF1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22251">
        <property type="entry name" value="PFF1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="700"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="737"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="767"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="179"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease transmembrane" evidence="20">
        <location>
            <begin position="449"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="19">
        <location>
            <begin position="793"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="594"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1903076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1023" mass="111465" checksum="FBAEB4AB3F922254" modified="2025-10-08" version="1">MVLPNPFAFRPLQVTFWAVAVYLSILIPVITIQEGVPHAPPESALPHGISVVEAWSDLANLTQNMHPANSHANDDVRDFLLRRICQILDRNGASYKTQADRAAEASSASVVTDSAVTDAVIFDDMLTNVSFTTAYSKGRRSGLYFEGTNIYVYIRGTKDEAGDWWTAAVDSPQAKAMQGQLVMVNSHFDSVSSSFGATDDGVGVVSSLQIIRYFSTPGNQPERGVVVLLNNAEEEFLLGATAFANSPLVPYIGTFVNLEGAGAGGRAVLFRSTDLEVVNAYRTAPHPYGTVIASDGFKQGWIRSETDYRVWVNALGYRGLDIAFMKPRLRYHTQQDDRRHTSQASVWHMLSGALASAKSLTGAAGDAAEKSETDAVWFDLFGSRLVLFALRGLFAWSLTILIVSPLLVGLLLYLLYRLDKDYLFRSSVEQPESADADSKVDIGGWKGFFRFPAALAVAGSAVYGTALLVCKVQPFAIYSNLYAVIILMATIFVFVFWVVMRVADFVRPSAVHRTHSLFWLFGIFWVLLVAATVGEDRAHIASGYVIVYLASSVFGSLIISLLELFALKTKATYIEELDSRMDALANSDEGDALISPTPGEGVSNNESAIADEPNGAGESAGGGLDDEVPTETSPLIGGNIRNNRPTTFATGYRRSLSALMAERRRAEAAAELQNSGLWAKEFQPFGVEQDWSKYLPTWTWFLQFLVLGPFNLIILSQLLLILGAAVQQTGTDGSDLLMPYLLVSAFSILALLPLTPFLHRVSKHIPLFFAVVFIGTLIYSLAAFPFSAENPFKFALCQSFSVDHKNSSVTLTGYEGYIGEIINNLPSAAGRPWTCTDSGGRQSGLLDCTFDGTGLEPRVDGDTTSPFSGNYDGLISVNTTRVSGKLAASFDINAVNTKVCGLRFDRPVKSVSVRGSGKGLDTRFDFDKEPAPSDGNWEIGDFTLWRRDWESPWTVDVEWTDDDDAESNTAVALTGHVLCRWGDANTPGTAPAADEAWKYAPTWSIVTIRQNPPLVQGSKSFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR01</accession>
    <name>A0ABR3ZR01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF962 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21304" checksum="22FFB3C4033BB23C" modified="2025-10-08" version="1">MSLDLEKHLVSYGAYHHNNVNVVIHMVCVPLILVTSFWLASNSPTIIPLPSWLTIPNLPLNLGTLAALTWGALYVLLEPVAGTALALLCLGGAAAGNYALIHFDAHTVTTYAAATHIASWILQFIGHGKFEGRAPALLDNLFQAIFLAPLFVWLELLFAFGYRQELQGRVEKEVQKEIAKFRASKTVTAKNGKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRK5</accession>
    <name>A0ABR3ZRK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000333</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="61"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="520" mass="55153" checksum="56E6869566B07368" modified="2025-10-08" version="1">MPRNSSALKAAAAAERTPLLRDVDGIGNGILGGDNTDASAAMVSMIVPAPADEDRPMPKTQVALLCFARLLEPIAFFSVFPYINQMVQDNGGVASSDVGFYSGLIESLFSLTQALVMIGWGRAADRVGRKPVLVFSLIGMASATALFGTAQTLLQMILFRCLAGVFAGTIVTIRTMLAELSTAKTQARVFSWFAFSGNLGLFLGPILGGALATPLGRPKAGESTEDLPFLAVYPYALPGFVVSGLGYLAALLCALFVEETLVVKKKKTLSTPTSTTTTTVTESIANDDEPAPPTPTIGGLLKAPGVKIVLYVYAHVMLLAFSYTALVPLFWFTPVDLGGFGFTPMQISAMMGLSGASQALWLLVFPPLHSKIGTNGVMRLCAAAYPIFMAASPFASLLLRIWNARTLFWIVVPLLMVLGSGVSMCFTAIQLAVNDTAPSPQLLGTLNALALTGVSTIRAFTPALFTSLYAISARNQLLWGYAIWVVMVIIALGYTVAARYLPDYDELKKARESQSGGEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRM9</accession>
    <name>A0ABR3ZRM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000618</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF6">
        <property type="entry name" value="PROLINE UTILIZATION TRANS-ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="633"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="775"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="807"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="843"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="870"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="940" mass="103663" checksum="8BCAFD9B69B537A9" modified="2025-10-08" version="1">MHDPRHRPSYRTNSTTGTSGQPPTMGPSASEPAPAALLRLMRRRVPPEKRQRTEMSCDWCKKKRCKCLRSASGDTCRACSEIGRPCTTTEPRKRRVYGSLSSPSGPLGQQAHIPPATTAPQASSTASVSSSSTSSPHSPPQGPSMNFDSGIHNMNIDMSTTDPRLLLLHPEPQRHQQQQQHQHRLPAPRQQMTVAPRDVETTSLDALVVAQKKMPPPALPPQQKRLCDERLFEDALGFPRYIGPLGSYTLLVKLWETMAVWSAPMALRDSAQTMSQNQPVLRIGDVDGDDGRRIELPPREVADVLVALFFDKVHCDFPIFHRALFQASYENMWAPLSPSPPHGGPRANQHRHHHENPMNPDTEPAWLMCLSMVFVLGLEAASSQSSAIRRLVGNTARREALKARYLAKAKEVLPDVISGSMLVHVQALMLYCRYLHITRNRNACWNLTGAAIRVAVAIGLHRNGVHGKCSPLERELRRRIWWTLYAFERIECSSLGRTSAIDDAECNVGVPTEGLLDMSDIIPLGYVEVHAELMTILGSICKHQYGGSNSSGGGGASASSTGGVDVPRDQIDFAMASSAALDQWHAQLPGHIRLNADSPNTHQRAILLLHVQHHYTVTLLCRPFLLALVAKNKPGPKGAPSSSSKKRQQKRDTMAIDAIETANDAPASSSDMLMFARKCIDAAKAAVAVIDRLFRAGLFNSKTWWDVYFIEATCMVLALGRFVNDKDLRNDVGILDALRTCIHILKECKEFSPTMHRFAVVTQDFAQALVAEVPKEPGEEAPPRQAQSQTIDHQVSSQLQPDERRGQQSQQQVNCHQNEQRQAQQHQHGQHQFLGHPPHQPFLNPSVTNMNSFSTTHTVRDVDDLGGDPGSNSTAGSQSGSSPDESFIPAIPGLISGAHHMTGGSMLPDPFSMPWNLADISQLWGDFVEPPEHWWQQGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRQ3</accession>
    <name>A0ABR3ZRQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851:SF1">
        <property type="entry name" value="GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="258"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="650" mass="72914" checksum="FC9CF5942C1CABB2" modified="2025-10-08" version="1">MSLFTWCARRSGGLAMIWLGILSYWVISRESAASRYGHQAQPNDSLSAPRYSPNGAGIWTVIFSWYCLLIHVLVFSFPLRACWAIWDLTTSLRKTARSRAVKDFKFGHRRRDSSTSLSSSDTLTPSRASSSASSDAGDADTEFLTDSEAEQGRVVHAIIIPNYKEEMDTLRETLDVLASHPMARSSYDVYLAMEQRESNADIKAMSLIAEFVKKFRSIDFTLHPADIPNDCPGKGSNVDWAARKLSERYPVACRKDVIVTGIDADSHLSSNFFALVTKMHLSFPETAATTLYAAPIIFDRNAHSVPAIVRVADILWCAAGLSGLYRGSTIAPPTSVYSLPLQLVDRVGGWDRDSEAIGEDLHMYLKCFFALNGNLTVRTVLSPISQTNVTAGGYGKGVGGIVSDMRARYKQALRHMWGALDTGFALRKLVELWRNRKQTSRAFRPLHAYSRNSTDTYVPDVQLDTLTSSVDSDQEVDKGFFSDVTHETIKGPNYVRLIVLFHRLFEAHFLPVQMTILVVMSTLYMWVTEGADDIHGVNWIFQICKYLRTLGFMQVAFYLFMYENFHKIAVATREKEMNDAGLAKGMNFSHRTLRKNFIDYIMVPLVAPIYGAIPCAQAQICHFWTVDLVYTVSKKVTRQRTKSVSAEAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSR6</accession>
    <name>A0ABR3ZSR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="65"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="302" mass="32689" checksum="3A4A0F94EE901846" modified="2025-10-08" version="1">MAPSATTVTDAPVDATKAAAAAGTAPAKNAFFEEVHFLGDKDGKVVIRSPPTFANKEDERAYQKQHLAAAFRVFAKQGFDEGVAGHISLRDPINPDHFWINPLSTHFSQISVSDLVLVNDHGEVLPGGAQSPINGPAFAIHSEIHKARPDLNAACHAHSVYGKAFSCFGRPIEMLYQDALRFYNDLAVYPRFGGTVISTEEGARIAKALGPTCRSVLLQNHGMITCGRTVDEAAFLFIALDRCCHAQLLANAAAACPGWGKVLIGDKEAEFTHKKSGNPSKMWLAFQPYYDQVVKEDPSLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSX0</accession>
    <name>A0ABR3ZSX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="470" mass="51676" checksum="67168081E068F553" modified="2025-10-08" version="1">MEETGRENDVVVFKLVDALNGTDPTAATTELKTKFQLKGTSLGGQTPNAGGLVVDEDIGVDTLTVQCVVDSVVHGTLTSDQFSEPASLFIFEFAFCPRSRRRRFRDIAITLTFTAGTELVIQPENRWKTGTTTIDRQRSHTISPSLEGAVGPASGTLSYEWQQTDSRKIDDHVWIEGVVKALGERPDGRRVADSAVWELHENHQTDSGVPSFFRTAVLLKRESTQRNEPFQALLSITGDVHTHISDWAKIHGIKDGHGSGSSPKPARETRKLRKGPHEVDPEDKDTVPMTAAKIPLFFNPTLPDRNPLNLDKTNLQSIDLSKFKGLVHVRSWTESTEEAAQSQNGAPPSRPPAQPQTELPVRPPAPVDNTIARDTVPTNNYSPAPRPVTQPTVLPDLPPVAAIRAPSQVSDLSTIGQLDARLAELATELALVDEEARYMRRMIELVAEKRRLVKETHSLSALRNSALETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTK9</accession>
    <name>A0ABR3ZTK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine synthase 1</fullName>
            <ecNumber evidence="3">2.5.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CYS17</name>
        <name evidence="3" type="ORF">Sste5346_000175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007989">
        <property type="entry name" value="PRK10717.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="2">
        <location>
            <begin position="61"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="392" mass="41650" checksum="864BCB76C35BCDB4" modified="2025-10-08" version="1">MFRTGMRRLASAAPARNALRPAYFSVSASSSYANPSAANPPSAHTLAVSSSQGVVDGFVGAIGNTPLIRLKHLSEETGCEVLGKAEFANPGGSVKDRAALYVVLDAEERGLLKPGGTVIEGTAGNTGIGLAHVCAARGYKLVIYMPNTQSQGKIDLLRLLGAEVHPVPAVAFDNPENYNHQAARHAARLENAVWTNQFDNTANRRAHIETTGPEIWRQTDGKVDAFTCATGTGGTLAGTTRYLKDISGGKVKSFLADPPGSVLHTYISSGGKMIDRSGSSITEGIGQGRVTDNLQPDIDLLDGSLTIADEKSIAMVYRCLAEEGLYLGASSALNVVAAKEVAEKLGRGHTVVTVLCDGAYRYADRLFSRKWLTEKKLIDAIPKELQHHIVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTW2</accession>
    <name>A0ABR3ZTW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1903539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="171" mass="18987" checksum="D9277CD1A3D0CB49" modified="2025-10-08" version="1">MSDEPVRLGTRPYFTRALSSSAASRLESFRDQTAFETAYLVPIAYAGEWHARGFSSLITNPPPPPREGDTINSAGHELIYFKPDLLGLAGTALDQQLLDNRRRPPEALFNRHFEQAILCNVRGTGEPHLEFDFPPGSDMVGEILAAPRAVQRMEFELFTRLGGSEAPQDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFP3</accession>
    <name>A0ABR3YFP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010429</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000145">
        <property type="protein sequence ID" value="KAL1887123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.60">
        <property type="entry name" value="alpha-galactosidase from lactobacil brevis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038417">
        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF3">
        <property type="entry name" value="ALPHA-GALACTOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00743">
        <property type="entry name" value="GLHYDRLASE36"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="762" mass="83854" checksum="9D36C5315A9E196D" modified="2025-10-08" version="1">MAVTEDKTIEWPTAGVRLTLAINDNGTVCLRSFAPHGAKQTQSESQSPYFSRAELPLHSVRLAGEGSSMGKTAKSLVGSCISERLRYESHQIVSQFGAGDNIERLDVSSADAKSGLRVTQHFVVYRGDIGHGDADDCITGALPVLRCWSTATNINKEGGQTLKLTQLSSATVGGLTTGGPREWPQEWTLRTATNTWFREAQWREQSLPDVGIDEMGVLGLNDNGGDHHCTQAIVSFSSRGSFSTGSYLPTGMLTRRDGEDTWFWQVENNGSWRWEIGDYEDAVYLCLGGPTAVDHSWSVDLAPGQSVDSVCVAVGHVMADWQAAFGALTTYRRAMRRPHSDMDRCPIIFNDYMNCLMGDPDETKILALLDYAADAGAEYFVIDCGWYADSTSHWWDEVGLWEPSTKRFPSGFRVLLDKIRARGLIPGLWIEPEVVGVRSIVGQDGSLPEEAFFYDNGTRVIEKGRFQLDFRHEAVIARMNSIIDRLVSHYGAGYFKFDYNIEVIQGTDVPSSIENDPSTSPEAAHLDHHRAYLAWVRSLLERYPDLVIESCSSGGQRCDYAMLSVHPLHSTSDQQDPVLYAAIAAAAPTAVTPEQGAVWAYPQPNWDDETNALTVANCLLGRAHLSGHLDLLTADQSALVRDGMRVYADIIRGPLRTALPFWPLGLPRWNDEWVALGMLAAGGNDAFLTVWRRRGKKITGVGKSVNGEAAGTIDLPLPRAFTSVDLLYPVQLKTEYALFAESSVLQVTLTGLAGARVFYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG02</accession>
    <name>A0ABR3YG02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000141">
        <property type="protein sequence ID" value="KAL1887162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="160" mass="17603" checksum="7B50A6FD802AC4F2" modified="2025-10-08" version="1">MCLQISYTLTCEHVKTQMIFCADAIPAASSSSSSSKKDHKNHKKDSSSSKKKKHGPSSSSSSSSHRQPKMIPCDNLTQQSLPYPTPPSFACDPQTAATSLLAPKCPLPDCPFEAKDRCWNCCWCGKGWNERGRCSCIMIIEGNRVQCEHICCPECEAAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGC2</accession>
    <name>A0ABR3YGC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000125">
        <property type="protein sequence ID" value="KAL1887364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045991288" evidence="1">
        <location>
            <begin position="20"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="160" mass="17268" checksum="819C13AD026630F1" modified="2025-10-08" version="1">MHLSFFWALTATAVSGVSAVPFATSKPEQIRSDQDPVFHFYLQAHPKNASQVVLGPVSTSEYFNIGGSIQSTNTSRYLNIGGDSTSYKTLTFDAAASTTAWQLEGDTIITSTSSSYGRQLNFLACKIDGGFWQVYLQTGSATPSGQTCSNYQSLHLPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJR6</accession>
    <name>A0ABR3YJR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="53" mass="5821" checksum="257DD8FF9F989C7D" modified="2025-10-08" version="1">MSIGDRSTGDRRPTFSIEGLGERSGSRAVSLGEKPYINPQSTSRREAQRAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKI9</accession>
    <name>A0ABR3YKI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Senescence domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009686">
        <property type="entry name" value="Senescence/spartin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045036">
        <property type="entry name" value="Spartin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21068">
        <property type="entry name" value="SPARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21068:SF43">
        <property type="entry name" value="SPARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06911">
        <property type="entry name" value="Senescence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Senescence" evidence="2">
        <location>
            <begin position="309"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="599" mass="62107" checksum="DC553C785724964B" modified="2025-10-08" version="1">MASSLNDPKLLYAITGVSAYHIANGTESSLTPAGPQTLSLLMVPTASPFADLSIDGNLPDNGGQGQEEDFYLHLHLPPELDLPLPATTQIYHQPPSSYLIPRWDLGRNSGVFTRIEFPAVGSRKGLQEDVDTFETILAQCTAFLERAPPPKISSRKEKPPGASGSSSAAAAARESAAGPSSSSSSRHQSRSGEKSGFSDEKQRASRSSRTTVSDDLPAYNPAAFKPGEAYAAGSHSSQSGGQLVLIDEEDGSVIGELGDHYQVIEDKNLMPGSKEPVEITLPTEAVPNISVAPASREYVETLHPAYQKSSLVANAAAASRLIVTTSEMVSKALQNQADKFAEKAVPSNKPITFQPSTHQHIRRINTFSAGAAGLSAKAVGQVGKVAQNLGAKLAGHKAHDSVSSTGSSTAYSGKSRRQPPTGLGPDGQPINDFRPGLLNKSLMAFSTVADGIEQAGRHLLDTGSTAATTVVASKWGNEAGEVTRNLTGGIKNVGLVYIDVTGVSRRAIVKSVAKGMVVGHVPGGGALVVGGGDGGGSVISPTGSPPPLPNRPTSTSTTDPRGHNGSGSNSGSSSANNSASVSRVRSTHDFADNNPYRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKK0</accession>
    <name>A0ABR3YKK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="2">
        <location>
            <begin position="213"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="432" mass="46201" checksum="6DFE6CEAB6241FB1" modified="2025-10-08" version="1">MQVVNRMSMGRQGSPLLGEGRPRSAFEGVSFKKYHADFSTVVGKDARHALLLSSAETSRNAFFHTGCVLVREPAAGSRRNSSGSGTSRAPSEEEVIYTTSNLLQTSSSSQLPVILISRVSLRRNADGDVTSTEWTKLRPPFAMPAGAIPYQTKAGAPVGPLAGTGARGSSGVLYCAQGNPGPGTSGLFYMPTGRPPVPLVSNYYGRDFNSVFDVVRHPEDGSLWFTDPCIGFEQDFRKRPQMPCHVYRFHPETSDLRVVADGLNRPTGICFSPDAATVYVTDADTLYGGGGGSGNVNFVTGNNGGGDGRRAATIYAFDVLRRGGSDFLTNKRVFSYALRGTPLGIRCDAAGNVYAGCADGVEVWNEGGVLLGVIEVPGGVSSFCLSRDGEMFLCSEQQLWWVHLQPTTTETVSRWGGPGPVPMTVDPEDNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNJ5</accession>
    <name>A0ABR3YNJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GABA/polyamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GPT1</name>
        <name evidence="8" type="ORF">Sste5346_008875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF29">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="572" mass="61313" checksum="FB649AFC7619D57A" modified="2025-10-08" version="1">MSADDKDSLKRVDQEPVTSVLPPNEIPVLEGIHDSDDEVLAALGYKPEFKREFSLWSTFCVSFAVLGLLPSVASTLYYGLGYAGTPGMVWGWLIAMAFIQCIAMGMAELCSAMPTSGGLYYASAVLAPPKYGPFAAWCTGWSNWLGQVTAAPSVNYSLAAMILAAASITHPGYVPENYQVFLLTVFLMIIHAVISSAPTRFVAQFNSIGSTFNMAALVVVFVVILAADNRSSQGLDRFNSSSDVWGEFYPGTDFPKGVSILMSFIAVIWTMSGYDSPFHLSEECSNANIASPRAIVMTSGIGGAIGWAFNMAIAYTIVDIDAALNDESGQPFAAYLLQVLGEKAALACLSLTIVAGFSMGQGCMVAASRVTFSYSRDGCLPLSRYWAKVNQTTKTPVNAVWLNCFVGSLSVLLLFAGDAAIGAIFSIGAIGAFVAFTIPIAIRTFFVGSRFRPGPWNLGKYSYVIGVLSTMFTLLMIPILCLPAVTGADLDADGMNWTIVVWGGPMLLAIVWFWVDAHKWFKGPKVNIAHMIHDQQVAPFVIQGQDDEAGEAGELDSNQPIVPSKKDSLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP18</accession>
    <name>A0ABR3YP18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008767</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="863" mass="95080" checksum="E73577B7252AAEDB" modified="2025-10-08" version="1">MSTAPAPSSSNPAAQNDTTKRRRASRACLACRARKVRCDVVLCGKPCTNCRLDFSECVVQLRRKNRTIVVPSNNRLLSVKETSESEDDSTHSNTANTKTEPTVSSTHLTTLPTQPDTRDNEVNSMPPFEWNDAIASMLPTVEPAATTRSHPSISVSDAPSGESLGFDPSMGSDSSFSDHGLGGDNDLDELDMLLNMEEDDQQHKTQKTDDAPLTLSQPPLDDEPMSYELLSHTVDNFSLYGGGLNGTTHDTTGYSYASSSSEAWQRMHFPFSSSLFTTANANIVSMPFSAAMDVDSAGLGLDMVMPPESGVLPPRQMKVRTREPTPEATPQPQQDMTPESTPVCAEEESAAVPATTTTTTTDVPGAAPTTTGLPLIAATKTTATRSNNTTNANTNSGPAFVIFSRYPFLSSKTLWKLDHEDDAQLLEQRGCLHVPKKPILDEFMKKYFLHVHPMVPLLNEHDFWAMYNSPTPQTKAFGQMSLFVFQAMLFIVSPFVSQSTLSQLGFSTVPEARANFYRRAKTLFNLEEGRDDISTAQGALMLTYHSPNMKDRTNSFWMSTAIHFARNANAHRYYDLDEPKNAFKLGITKPSLTIQRRTYLKRLWWCCVLRDKVMSLGMRRPMLIGPADFDVVRPGLNEHDCSDEIPGSSVYSPATKRVISQVFCALCELAGILTGVLDVCYPASGTRPRSDRPPAMVAQDYVAKLDAWYETSASQFQNSLSRIGNNVEDQLVLVTNAAYIYYYIARASVYNYLSHVLATHPEAAASSETTWGSPPAKVDESFRGVTKSLAELKRRDLVRYLPNTFVSMAILPFKWHVASVRVTGGKVSGKETDLTVYYAVFKGFGEIYEMTDSALQSVGTITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP26</accession>
    <name>A0ABR3YP26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045794150" evidence="1">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="110" mass="11242" checksum="3683215529D1069F" modified="2025-10-08" version="1">MKASVILSAVVLAAPVLGAPAAAAPAADAVAARGKTGYATYGDYPPPKGGYASYGDYKGDGEVKDSGKGKDNTGKVDGYATYGDYPPPAGGYASYGTYRRWVESIKSFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP60</accession>
    <name>A0ABR3YP60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="77"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="525" mass="57307" checksum="E703D9E9EA273F99" modified="2025-10-08" version="1">MSSIRKSVDEKDAGSAPTASIAANEPTNVADLEGNTHGSRDLDIAARFLAGLDPSIINEPISAKEARKVLWKLDLHILPVLTLVIIVAAIDKVIISNASIYGMLTDDHMTTAQFSWIASIFYFAYLGFEAPAGYLVQRLPIRSYLAAAVFGFGVLTFCTGATTSFASLAVVRFLLGAFESMLFPTASIITAMWWTRKEQPIRVAMYFNTLSSVVTGLLAYGVGHSSSSIAPWRLLFIILGALTTVLAAFVYIYIPSSPVEAWWLTDREKFICVERVRQNNTGVEDKTFKMYQVVECLKDPKPWLLALFSVSQNICNGGLVTFAAIIVTGLGFTPLKTTLIGVPTGAIGTVWQILLALLSSRLPGYRCGIIVGANCFPIICAALMFSLRGHVSNLHLLGAYYGFYSYWAPYVLSTSLNISNVSGHTKKVTANAMFFIGYCVGNIIGPQVFRSKDAPDYKHGYIGILACLVVSSISIALYGLLCRWENMKRDKAQGGDGTAAVEPTDTANAFSDLTDKEKPEFRYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP89</accession>
    <name>A0ABR3YP89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF37">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="63"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="482" mass="52852" checksum="821CB9FB4A8A1BAB" modified="2025-10-08" version="1">MSSILFTDATIITFDDATKRVKIVAPGSLWVKDDRIAGIYDANTPVPGDLPVNTEKVDATGKIISPGFIDTHRHGWQTAFRSIAGNTTLPEYFYRYGQFASLGAFTADDVYAGQLAGLYECLNAGVTTTLDHAHHCWDAATSKAGLDASIDSGLRVFWCYTFHDLTNGFDHAKQLETAEQLRTDERLKTSPASFGVAYDGWNMSPAETVSSVVDFITTKDIPVLTTHSLGGPWVIDNGPSVLEKNKVLNTPVPVVISHASFMSEKDVELLRSSNQYVSITPESEMHYGHDNEHSHEIMDQCCLGVDTHFTFSTDMVLQARLWLQATRRALYREKLAEKKIGHPNPFDVEQAFYLATVAGGLALRRPDLGVIKVSAKADLVVFDGDSPNMLGFVDPVAAILLHSNVGDVRHVLVDGQWRKKDGVLQPAANTGADWTAEIKPKFLESAKGIQATWAAKPLPTMEGDFLGLTPYAVIDKVNVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPR6</accession>
    <name>A0ABR3YPR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="37918" checksum="748433C1D42EF47C" modified="2025-10-08" version="1">MPATIPTRKLGRDGPAIPAVGFGLMGLSIAYGTPGPDDERLAVLDHAWEIGATNWDTADFYGDSEDLLGKWFALHPERRADIFLASKFALGFGIRPDTNEPGITITSTPEYCRASCEKSLKRLGVDYIDLYYIHRVDGVTPIEKTMAELAKLRDEGKIRHIGLSAPSSTTLRRAYAVAPVAAVQVEYSVFSLEIEGPESTDLLKTCRELGVTTFAYSPIGRGFLTGQIRSADDFGPQDLRRAVPRYQGENFAKNLVLVDTIAEMAAKRNPPCTSGQLALAWLLAQGDDIIPIPGTKKIPYLDENTAAGNVKLTDDEVAKIRSIVDDIGVVGDKMGQGVITDYGDTPALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPU1</accession>
    <name>A0ABR3YPU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oleate hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010354">
        <property type="entry name" value="Oleate_hydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37417">
        <property type="entry name" value="67 KDA MYOSIN-CROSS-REACTIVE ANTIGEN FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G09970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37417:SF2">
        <property type="entry name" value="67 KDA MYOSIN-CROSS-REACTIVE ANTIGEN FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G09970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06100">
        <property type="entry name" value="MCRA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="69194" checksum="5F39B76117F100C8" modified="2025-10-08" version="1">MRRLPQETHAYLVGGGIASLTAAVHLHYDAGVPADQIHIIEAAPLPGGAMGKGGGSPRVDGDVPAWEKGYTVLAARKLNFSYRCLYETLAKVPSARHPGRTVLDDVKGSPSPTPKPEPEREPEVATEEAPKTNGGSASGSEYEVVDMPTIPPTPRTASSFVSTEPPLKPPTFPARLVARGDDGRPQVVNVQSMGLLPAQRMSLLGLILATEESLAATAMSEGKAEIQAHFQPDFFESKFWDVWASLYAFQPWHSAVEFRRYLLRFLHEFSHISTLSGIDHAPLNDYECIVLPIEQHLRQSGVVFQYSTRVEEVVFADGDDLHVSALRVAQNNSQSDITLGPHDIVLLTLGSMTASVLFGGNDRAPPPLPPQDAVLRDPGPVWRFWSRLADPAINPVHHTAFGRPSVFYSHVAKSSWLSFTLTLSGKAAALFTHLTTWAGFGTADTNATDGTNTNGPLITFRDSPWMMSITMPHQPYFTDQPDDVRVLWGYGLYPDQEGLHIRKPMMACTGAEIFAELLSYLDLPADLASLFTAPCPSGVITIPCLMPFIGSPFLTRTAGDRPNVLPSGKDKGNLGLLGQFVEIDRDVTFTMEYSARSAQLAVYGLMGIDGERTPPAVHRSDQDVTVLGEMLMTIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQT2</accession>
    <name>A0ABR3YQT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="383" mass="42905" checksum="4AC6331C3E173FFB" modified="2025-10-08" version="1">MGITTRHVGNEGREWRPGNVRSRDDLQVEDGEEDYDNDEEERRDAFVDYLEEMMQEIDDNDNGKVNDTVVDKAMAKKRVWAVIQALRDPVIQLPDEETNNVAIWQKMDSLVNSIDFAWTGISIDGEEEEGEPRKIDTDRNVTAWYGGRCPLTIEAVGSSAAALLVPQFVVQSALKLSLTATGFNELWGEGTVGGVASIAGKQTVNTLPLGSTALKLWDRYMFALRPIEDPDRPLHNIYLQVVWLLPDPQTIGIPQGLADGDIIHLRTSDPEQHPLPSLPLLQMQCRARQIVAGIRTPSILREIFRGNPDGNIVEELDDDEDIDVEAYGEAEEVPLDWQSLLKAAETTGVLSNALVDRWGKAILRKEQRDYRRAAHASRKKMAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR73</accession>
    <name>A0ABR3YR73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Utp8 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018843">
        <property type="entry name" value="Utp8_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10395">
        <property type="entry name" value="Utp8_b_propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Utp8 beta-propeller" evidence="2">
        <location>
            <begin position="7"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="986" mass="106318" checksum="FF880DA4373E2024" modified="2025-10-08" version="1">MASNFHIQKPYVLASLPRSLAQVDGKSVVGEVYGQRPGVKKRRRAEVVVGIDGESANIYDIASSRLITSYPVPPQAKFSCPPCSVRLRSSASKDATVARYTYIATREPARKLSLFKDTVEAAGATASGSVTVSLGRTGDIIALYTLSLPAEGATTSVDLLAIDRDGQVTCFDGETLKEKYKASVAALSQDPVPRGSNMRVEFVQMGLASDVVKGLGLGDYLSGFFSQKIDVEGSSGGFNPDVLFVITTVTGGRQAAARYLHILSADADRDVLVQAHYIRLPATTTENDASTTYRLDILSGSLFALEGENVLSYDLTRSVPRVVSSIAIPGVTSFLRLSKSSILAATPTSFSVYNPLFKSLQASTTLEVQASVKSASNEAANTSAAAHACSFVSFFPQLELAVALLDSNLVAVQLEPPRTRSKKRRADGLLIDSIGRGASSSLADTKTTSDDALPKKYLPGTMSASYLAQFNEDAKSADALLEAEDVVAFDDLLAEKLGIQSVSDWRWQRPLDTTATTDAMDETQDGGEEAATTTNGLANGTTNGLTNGHTTTPPPTSSSPTTHHVKYPLSDRRWVIYAISRIFSIKEEQTGGRLRLRCKFPASDILNYLVDAGHLSVANTRSALREFLRDVDEDDQLLGESLPVVLAQVDPSLDLLLRWLYETKLGATELLSATLLLMRSLELVDKPEATKPEAKQRTEEDSADKPERELDQLDQQLHLAEYFLQHVENDPRDLALDIAIGKLGSCPAMATVQGLRRIFRTDEIRALIEVLRKQMVDQGWATRYMDMDEAKTGAAAAAAAADTTPLNYSIRLIADLLCRCIDAVRPGEWLINDEEIDTSSEEVALTAPNNSAVSDPTGADFFALLKWQVSAALEGVQEALYLRGLVGETVRYGMGVEKMATKASILAKNGEENKIRPQTVVAPASASVVSGLPLGLRAPTGLTRHTDVAPTKVVSGSGEILKRTKRELGHLTSKKVGAYTLERIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSH2</accession>
    <name>A0ABR3YSH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="110" mass="12325" checksum="ED28A423FFBB16FD" modified="2025-10-08" version="1">MPIPAPGPGYTDPLIGDLIRAHHATYEIMQRRDKGDEAILDCKNMDKLRDFLDAPELERKADVTETLAAIKKGSYMLVDYIAVSWSSDTPALSENEENELRMRFVSGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTH7</accession>
    <name>A0ABR3YTH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="195"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="636" mass="68644" checksum="4CE0E14A21993A4D" modified="2025-10-08" version="1">MTAHDEEKAALGTAPSSTTPPAAATTTETTTAPSTTTAVPTVSTLDEKPHSETKETNGDDGETSNGTTDDDEDDDDEDDARDASPYEVVEIEQVDGNGLSAAEKGVAGIVDDDEIQADENEVVHHQGGSRISATLSRIASNASSAVRRNNKAATAARLAASPIPLMDLDKGIVGWDSPDDPEYPLNFAPRRKWLVIVFLASMTLMTPLASSILAPGINYMDADFNNDNVTIGSLAVSIYLLGYAVGPLMLAGMSELYGRHIVLSVSNVFFCAWQIGCALAPSLDSLIVFRVLAGIGGSACMSLGGAVIGDLFRIEERGLALSIWTLGPLVGPSIGPIAGAWLAQTIGWRWDFWIVLIPGVINTAVIAVFSRETSHHVLVRRKVNRLARELGRDDLRSCYENPDKPRPTTRHALLQGLVRPLKMLALSPVLLVISLYTAFAYGVLYLLFNTIPMVFQEGYHWSIGITGLVYIPLGLGYCCGLMVFARMSDGTVIRLTKKNGGVYEPEIRLVDCIYFACCLPITFFWYGWSADKHVHWIVPVLGLFPYGFAVIGVWQPSQAYVIDAYGHYAASATAAFTVFRSVVAAFLPLAGPTMYATLGVGWGNSLLGFICIALIPAPLLIYRFGGKLRKRFPLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV02</accession>
    <name>A0ABR3YV02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein mlp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MLP1</name>
        <name evidence="9" type="ORF">Sste5346_007465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057974">
        <property type="entry name" value="NUA/TPR/MLP1-2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012929">
        <property type="entry name" value="Nucleoprot-TPR/MLP1-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057577">
        <property type="entry name" value="Nucleoprot-TPR/MLP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25481">
        <property type="entry name" value="Nucleoprot-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25785">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07926">
        <property type="entry name" value="TPR_MLP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoprotein TPR/MPL1" evidence="7">
        <location>
            <begin position="185"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="NUA/TPR/MLP1-2-like" evidence="8">
        <location>
            <begin position="494"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoprotein TPR/MLP1-2" evidence="6">
        <location>
            <begin position="1094"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="948"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1226"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1523"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1742"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1880"/>
            <end position="2186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="164"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="421"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="599"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1273"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1578"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1654"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="975"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1226"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1528"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1746"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1907"/>
            <end position="1963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1967"/>
            <end position="1977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2014"/>
            <end position="2065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2066"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2083"/>
            <end position="2092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2102"/>
            <end position="2120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2144"/>
            <end position="2186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2186" mass="241552" checksum="7F6524CFD1A24B84" modified="2025-10-08" version="1">MAAAAVDVGYLSTHLGVPETNLSTAVTDPTPELVKAILDAVTAKAHEFDELYAAKLNVDIELESVVRSSEARSESFKTAAETSRKDADDLRRKLQDEENARRAIENELQTITASGANAQTEIERLASRNASLEASNRDTLAILESKTSANAELAEELQTQHQKTLKLNQEVTALQQQIQAAQATTSSAKFREQSLQQELEFARKNNEWFEAELKTKSDESLKLRKEKGARIAELQRQTEEAQSTVDALTRSEKQLRTRLDDAQRKADEALAKVQQLQEAAARSEESFRAELASSARLVELKEQQTETHRNRLREVELRLEQVKDESADEVRRVRNEMEQLRQDLQQAERLTQELEAEVDRIQAALATPAAASVIQATPGSAPQTPRANGSAAGGLLRAASPFGTPGSVLRGKSSISAAQALEELYKTKGELNRERRRTQELGQELDEIMSALEAKSPEIADLQEEAERLRSENVQISRLCEESFSERDIAKKAAKKAEASSITAQAEIEILRTQLRDLSTQIQMLVFNIQAREKGLDNLTDEEERQFERLQRGEVAEGSLDDMSDTHQFISERFVVFKDISELQKQNTELLRMTREFAMKMESEEANEAKRQAEQDHAELVSLRDTVGRLQDESKAVTIRMKSYMTERDMFRRMLQQKASHAEIASVLGVGGDAPGTPGQNTREVLASIEQTASSTDDAELTVALRELQNNFDAYRNEQGVDRQTMRAQVDKLSHERSTLQGEIARINSQLTLASERYEILQSNYAALETDNKALQEKNQSLSESYAKQDIRTQQVAMDLVEVRSLLESMRNENANLKAEKSLWKGIQDRLAQDNENLNQDKSRLNTLLSSQQSLLNERELSESETKRRLQTQIDNLEAELTTTKRKLSEEIEDAKKLQLRKEYDAQQSQKRIDDLMASITQSKEELVALKTSRDHLQARVNELTIELRNAEERTQRLQPRPTPRAPPAQQQTDENADGGDDEGDSASRIQELESEVSDLHRDLDLARMELASSKEEANSYKDIAHAIEEDLNNLNEAQEQYRQEMDGALEAKEVRIKELEQRVEALSAELATSTNELNGLRDSQADLARKFDDEKRILESEIARLKDSEDRYKDEKKYHQSDLRAQAEIATRAQKDYEQELVKHAEAAKQLQVLRSEHNHLRTEAASWRAEADSAKVALAQSESSWEERRQQFEQELVEIKARRDDTNAQNKLLGQQLETVTAQITSLQQSRASSGAGADNSGDNADGTPSAYADAATEGLRELNNYLRREKEILEVQYDLKLQENQRLQQKHDYAQTQLDEARLKLEQERRAQADVGRSSQTHKELMEKLNELNLIRESNVTLRNDNQHAQAQLVLKDGKIEMLRNQIQPLEQKVAELENQKLYLDEEVKQITEDRERWQKRTESILSKYGRVDPTELDQLKESMAALEAERTTLQTTETELRAKITELETSLESDRGQWRETRQKLIEQAKEKARQQGAQIRELTSQKTELQEQATAATTRLATIEQELEAANAAKTALEGRLNQQQQAPQQQQDESFAPATPAPVASMDVDSQQPAAESGGLNAEDTALLQQEVHQLRGELEVVRTEKAAVEQELIGLRTQLDNVVAERDQALAQVQAAQAQAQAPAQNPSGEYGAATATNGFAAAATPAPLTDAEKEELQQRIAAAEARAVAFEQKAKEVEDNIQNTLKERSDKMKDALNKKLKEFKEKAEQEAREARDKLQSELDLRVEQEKKIWMAEQSSAPTSATAGTSTEPGEVPATPAKAEPGTGDVPPTPPTGTPLDLSKLGDTETRELLANNPTIRSIVTANIKKKIESETKKVRDEVEQAVKAEYDAKISSARESGQMMAEKKSSIRINMAENKLKTATAKLDVVSTAATQTPQRPVGEVWSIAKDARPPPATPAATPATPAQAPATPAQAPAQTQVPTQAQAQPQSTPAATPGALRPPQQQQQRLSSLPTKPQPGNNNSQIPTSLPAPVVGGPPALDNPFLTKPSEIPQAANNPFAKAAQQQQQQLQQPQQVQHQQQHQHQQQQHQQNQPQRPQSALGQQQQQGGPRSGIPVPGGGRGGAHGNQQSNRGGAGGAGRGGVYQAPRGRGRGGIGQNQGRGGGNTGQGGAANLNPSADAFNPGNKRPRNDGGNDAGGGGGVKRMRGGGGPSGATGGQAGGGGGAQAGGGAGGQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVC9</accession>
    <name>A0ABR3YVC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF4">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="224"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="462" mass="51050" checksum="EB0A1E04A96A1DD6" modified="2025-10-08" version="1">MGSTGHDSSLPSAADPSLILAIPTVEERRKVWELTHPMWGNALVMDDYLHREDYLTTVPLAMESGITHWILTDGTRPANQRPILSSCETLRKHAMSAEAAESPIVVDGIAHGIASVFTDPQYRGKGYAGRMLTELGKRLERWQVGSPKHEEVGPNMMAASKEDDKPKTLFSVLYSDIGKSYYAGKGWPAFPSKHLSFPPLALPPSTTAEIEDGTFSYTSKAVHSEDGSFTVTPLGYHELTELCPIDVQLLRARLIRRATRRAVLGGGSSRRSLAGPSVTLVPDLNTMLWHLMREDYMTKHIFGKTPTVRGALCTLNNSPKPDGSGIIVEKQRSIWVIWTRGYYSGLKSQNGEGNTLYILHVVLEDLDDDFPADPGEVPISQQHVDGFAAIVRMAQGEAAAWKCGEVQLWNPTPAQRILAERSGIAYKEVERAKDSIPSLRWHGAGTLSEDVDWVANEKFGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVH6</accession>
    <name>A0ABR3YVH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF14">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="471" mass="52674" checksum="BECA682A9160CAF2" modified="2025-10-08" version="1">MAPTLEDLTSTFVFAAGPHTDNKAVLAELPKGLPMDPARQRQGHRKSKLGCDNCKRRRLKCNEEMPCAGCWRRGEWCERPDRPERPKATQEMRLRQAAPKAMASMGPLNSSTHASDAVVNLLHLKLLHHFQTHTASTLVFDAAAWDAALQLSFQFEFLANAVLCVSSRHLSSLSAPNDPETASYTAAASSHLCRALAGFRQELQTKDFFTATHLDAFIATSTLLQFELWSSTDFARHGGARHGETGLDMERDRLFTFSASLKQVFLQSVPEALRHQPDSVFIPYIQHNPAVALNEHARISSESVEAYRDYFARRPEGNVAGEMRGRLEEKPPPFVRLQDSSKTSLWKPRADPVTTTTSLSTDDGGYAHVVGGLCLLMSFLPENQSSYSDSKTPTELPTSLLADLTRCVFSFPILCRGTFVALVHNNDMDAFFVLYHFYRTVRQVLPEKTCWWAHGRAATMEKALHNWLHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW66</accession>
    <name>A0ABR3YW66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF647">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="20"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="381" mass="40814" checksum="E433979CB3099B67" modified="2025-10-08" version="1">MTDEEDDDRTTMLALVHDPDTHSLTLSEVPIPVPTGPDEHLIQVHAVALTNGELKWPEPATQTPAIPGYEVSGTVVEAPNKSSPFQPGTEVYALTDFNRRGNACEFAIVLTSELRQKPEALSWEEAATVPLSALTAWQVLFVHGGLTLPNEPVTRPPTPPQIYSIVVGDDVNANKRVLITAAAGGVGLWAVQLARLAGVGHITATCGPANVDFVRSLGAHRVIDYTTLRNTGDAGSSSVNPREGGGSGRNSPSTTHGRTRSSSQSRYGSYYSSDKYDLVLDCVGGDTLKRAWTSARHGGTVISIVMPPDKLRPETGVGMDVRGVFFIVHADSEQLQAITDLIEARAVKAVFDSAFQLEQYEAAFAKVQSSHVRGKVVLRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA5</accession>
    <name>A0ABR3YWA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF24">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="557" mass="61167" checksum="E1C03BC5D9D924D8" modified="2025-10-08" version="1">MSRRACESCRIRKVKCSSGQPCSQCAQLGLPCAVVAGRPKRNNPVRGRLIAKARGEDDDDSARSLPPVAPSLASFSPAFFFDLLPAFEQLVYPFNPVICPDDLYHAIHAMDDSVEDRALVFAFAAATVFLAADETSNAMLSPSVVPSPGRRAARTQVETLVQHSLDAHKRLDSLHGLGGAKDNGDNEDDGMRTAVAEEPPVTIKRIVTCIFLEISMMGFRNYTRSFSLLREAITMLQIIQVRHPATAAGSGEDAARYQRLYWEAFIHERFLTIAAGYPSILPPLPGTNGQGHKVSLLPDPTVPAHIKLGFGRLVQLFLVMDEQFLKYWGQQGPGQTTLGDDDASVAVAWIEAKQAQLDIDEAEVQQIANANANDNANMSDSGLTELQHADLFITRLWLRTLVWQLALARGLLRSDPAAHYHPGHSGGHNAVHEGLSLHFPAQRLSAQLRLLVSRLASVASIGQQGSGIVQKLFEITSTIADVLTLPRSIEQQETIQREGYEGYEGQQTQHDVTDFVFLVQFVSQFARIREQQKAYLWDKVDQLRAQHGLESAGGHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWH3</accession>
    <name>A0ABR3YWH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Telomerase reverse transcriptase</fullName>
            <ecNumber evidence="2 13">2.7.7.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Telomerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">EST2</name>
        <name evidence="16" type="ORF">Sste5346_006814</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.49"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Chromosome</location>
            <location evidence="13">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the reverse transcriptase family. Telomerase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="2 13"/>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01648">
        <property type="entry name" value="TERT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021891">
        <property type="entry name" value="Telomerase_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003545">
        <property type="entry name" value="Telomerase_RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066:SF0">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12009">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01365">
        <property type="entry name" value="TELOMERASERT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00975">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13 16" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="9 13" id="KW-0779">Telomere</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="15">
        <location>
            <begin position="371"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1892731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="842" mass="94469" checksum="6F62061122F179C4" modified="2025-10-08" version="1">MANKRKRSKAKADDGQPQKRTKTDGDREVKTQGQPGAQPKKPVAPAARRGQTVKQDLLGRYFARVETLRAYLLTRLPATSRLRRKKLSAVGKQPHAAEVENLLSHVLDTTLVACAADSNKAVGDGRPASNDSDRDRLRETFSQTRCADESYVTVSSATEGFFSPQSEVIPNVYAVRNPQNAQTLKEAPWPQLLAILGASSEKIMTDLLLDCTLFLPVEAGDGNYVQLTGKPLFNAVSSADVNVPFSQAKQAAVKPKLPSDITFSRSRMFYTKASLTKSAGKGLKIAELPWLAPPKLKYSKLSKTDLEKRQEIFAEFVYFLFESFLVPLLATNFYVTESNLHRNQVFYFRHDVWLRISQPAMAAIKTDRFEEIKMKDAAHCELGFGKLRLLPKNSTVRAITNLRHQAPRKGKLRPARSINTTLRPVAAMLTFEMEEHPERLGSGMLSTRGMYSRLKDFKQRMHAKGKKTFYFAKVDVMSAFDTIPQDAMVSLLGKVPEHAAYQIKPHFEIAATEYNAVHGVSASSNTGLGLRKTWKTAARPSDDTSGFHDAVKNSMAQNKRNTVFVDSTSCWTEDAERMARLAATHISKNIVKIGNKFYRQKEGIPQGSVLSAALCSYFYADLEEKELGFLKEKDSDSEDCLLLRLIDDFLLITVNRSKAAQFVEVMQRGHPQYGVTVNPSKSLVNFNLEINGKTVPKLPSGLPFPYCGTTIHCSTLDLAKDRGSKPQNLFNSITVEHTRSQGYQFQRRVLNYFQIQSHQMFFDTSYNSRRTTLSNLHSAFAETASKMWAYARCMPKTKRPSAQLTIRTIEEVGGMAFGILNSKMRAQQYPDYKFDVSKPHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY44</accession>
    <name>A0ABR3YY44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Armadillo-like helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039868">
        <property type="entry name" value="ARMD3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013636">
        <property type="entry name" value="ARMH3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13608">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13608:SF3">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08427">
        <property type="entry name" value="ARMH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01158">
        <property type="entry name" value="DUF1741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Armadillo-like helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="739" mass="79552" checksum="76F02D5D8D079FC8" modified="2025-10-08" version="1">MEQSPLTQQPRPEAFQPKIVQLYDELLDHPDHIPGEGFWAEFFLLRPDRRALRERLDELSAGALLALEAQTQQLFGRAVSVLLAGSGATGHHTNGAGANGHRRNGSAGRASRANGNGTALSSRSNSKNGAGAPATSPPPVSTHTTSSSTVENTLATLATFLSAMLAKKYNNPSSDVIDLLAGLDRVDAVLSDFVAALDQLLRHGRTPAIRGYAVDVALAVTAGAYQTTLLTYFIQRDLFPSIIKVILDSPSASVSPFILVGLLANYNKFEFQNPYQLRLNDFVNEQAIHTILWGVGDACRGLRQQYIDIQDDLPEGWTLSSTLGMIGLGGGSSKKTPPKPVYDAETAKKLFAELPGDDAAVLLATYDFTHANKLFCFNLVALGARPAPPVSKDAKSQAALPPSPNSSEPPISSFISLTSYLLQHAHRSNRATLYAHLSLMVFRLLVEDPALCKRLCSNDDDARVAVRLCRQRAPHLPLVKTGRPIAASILDLMVDGITHNLRRRLDVGLYTLLVGILLRLVAHLSRTRTRLAYTHWPDLFRALLGLVRFLTTYAGDLRGPTSAATSPGGSATQQLDTLVDHVVNLLALGLSAGEAFLPTPASYDDLFYKVVETGEVLEKFRDTYQLGSGSGTPVAGRPSTNSIDTLLSVNAHYKQLLSEGAKGGKGGRVKGTSSSSSTLTSLQVAEVIKQGYETLSIQATAGLDGWEKYREADERTLLKKVARTAVADVKHKVEVPATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ04</accession>
    <name>A0ABR3YZ04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="189" mass="21676" checksum="8EF7BBDEA3634A28" modified="2025-10-08" version="1">MPTSRDHRSRSRERTPTDDNKNDNNNDNHLEHIIRKVLALALNKFDQNKVDTKEDTRAPNTERAPGERGGDNDLAKLVLSHAVQFGVRRYLKSREKKAKAKAVKSPKPNVKMPRYVGAPAGGPPLPGPLPGPPPGPPDRGIGSASQYYYPPSPQRCYPEDRRQERRERYERRLERERLEQLERMRAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZB3</accession>
    <name>A0ABR3YZB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloprotease m41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="89922" checksum="7E2886AAF0D8FBB2" modified="2025-10-08" version="1">MSSKLPSSTVDKSSAVDDALLASFTPEQRLFVERIKAEAEARAEQERREKEAAEARAEQERREKEAAETRAEQERGERQALQQQMDPTAFAEYLRLADKLLFKTFRLPPPSTTLKSSGMTRVTGKFYPQHLRPWASFEHDHTAMFAVLLNTLGDRPLFPSLTDVLGVGRDVSLGPADEMDLRPFIRAAIEKPAVRAVSAYLEITDDARLSSINFQNNAAGLDLAGPFLEQQQVDEETQPPPAKRQRSATKDIGIPDRWCVGFHRDQSRTHLLVGEYKAAHKLNPKKLAAVLVTVPPGEDFFTQVITSKEKDDEKDDEDTVADTQPETQPGTQPRTQPKTSTKSTVDRQRKTVPGSALVARVLCQAYHYMITSGLEYGYVASGEGLVFLRVLENEPDTLFYFVLHVSQEEEPAPEQNEPPPVRQPQQTAAAHLASMCILATRSTTRPRSWIDARKDDLKAWPELYDASVPPLAPAVLPPRGDPNPPRGGGGGSRSGGGSGRGGGSGGGGNNRPSGSTPKQPRPPSGTSYRGQATQTAPTQFIVELPTLPYCTQACLVGLCNGAPLDHNCPNVAHHREAAVSSPSSSARQGHHPLTAANVCSRIVAQLAENMDKDCECLDRWGCYGRYGVLFKITVTGFGYTLVAKGVQAVHRYILEREANVYLTLAARDANVQGRLIPVFVGLAELSRPLPLHSCASVARLILLSYAGPTLASPGMLKRLQAAGVDCEAEEARTTSELAIIGLRNEDVRPENLTWNAEAGRIMEIDFDQAWVNPKKPTKPTTPETECTRMNMPRSPLTKRTYSTGGVQPQLKKARHTEADKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0B4</accession>
    <name>A0ABR3Z0B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006173</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="99"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="198" mass="22002" checksum="50F528C6180453F3" modified="2025-10-08" version="1">MRTDQISEGHWDTRHRAMLDSVGLRMGILGYGSIGRQCARLAQALGMEMYAYTRTERATPESRKDTGYCVPGTDDSDGQIPSRWFCGAVRDDIDHFLGHDLDMLVISLPLTESTHNLISYKQFAIFSKKKTFVSNTARGPYVDKQALITALETGQIRAAALDVTDPEPLPQDHALWKAPNLFISPHSNSPKGSPVLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0L9</accession>
    <name>A0ABR3Z0L9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="455" mass="50675" checksum="6A2C74222AA57F00" modified="2025-10-08" version="1">MRLSSGVTICEQRHYSASTTNTGILLFTTAVAKAGSAPPASHLHISAQLSPDIDQGLIHHYTSRLCSLLLSRHAHPDYERLFLQSSILPKLQLMVEPLLACASLDLSRQFPAYRPLALAYYAQAVTNTRNTIARKNVQGTEDWLLFNVLHLNLFETWNSDATPDRTPVLLHIQGAAQILKLKLQGHSTVHSSTADMVVARIAAEAFVYHTVNWSMFHGNPIPITTMPAAELWDGLQPYLNLRPFPDASDAENSPVLGVPWQLYRFLSDLALLSRRGPSIDNETDLSTVRSLSDAIEDWERREEETQTQKAEKGSLPYKPSPYRQRTRLFVLALKLLILKLLHPTIATIDLRIQYLVSEATQLILSKEHSQTVLERTDFWPLLVVGSAAVDRSQVAVVRDTLQTMAQTMHSVAFAKTKRALETIWAQKEKEHDACDGLTMLLGGGGVPGLIQGDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0M4</accession>
    <name>A0ABR3Z0M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006393</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="52"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="47066" checksum="53C4492D7676F6AA" modified="2025-10-08" version="1">MADTRLKTQGDAATPETPELHEMHDNTPSAAREDGERPGVPAKDMDGATYLKIASAGFSFFVAGVNDGSIGALLPYILQTYGITTASVTAVYAANFAGWALAAVSNTHLSQHLSLGSMLFVGAGLQVLAQSLRAWLPPFGLYVVTFGLACLGQAYQDTHANTFVAGTRAAHRGLAFIHAMYMAGCLSGPFCATAIAASAPLRWPLFYCFPLGLGVVNMALVSVAFRDCLFRTVSASDTDERPAAGLLKETLALRSVWLLSLFFFFFLGATLTASGWMVAYLVDVRHGRVSEMGYVPAGFSGGALLGRLLLAEPTHRFGPHRMIFIYALLCIGLQLVFWLVPNIIAAAIAVSLLGFLTGPYFATGISIGSKLFPSHLRPTALSLVFVFAQIGGCIFPVITGLLSSTGAGDSVLQPMLCALLASTAISWLFVPRPKTSGTADLHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z150</accession>
    <name>A0ABR3Z150_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802:SF1">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="29484" checksum="42E7AAF15D2038C9" modified="2025-10-08" version="1">MYQRNEHAETSLVALRQLIRDNPLGQLTTAITADGFPLIQSSHIPWVVAVDDESSETEKGRLLGHMAKVNPQVKAMLASVEGKPTATPGVSALEQEVLVVFTSAVQHYVTPKFYTETKPMTAKVVPTWNYATAHVRGKATIYYGAGPPSGATTNVAANDFLEKQLDLLSDYSEQVIMDYTGEGDRPIPWKVADAPGPYLDIMRKNIIGIEIEITELVGKYKMSQEMRAGDRQGVVAGFGKLGTETATAMSAIVAEKDKATTAAKAAKAAEKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z162</accession>
    <name>A0ABR3Z162_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxygen-dependent protoporphyrinogen oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HEM14</name>
        <name evidence="1" type="ORF">Sste5346_006293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="858" mass="94944" checksum="FE95395B909B9D20" modified="2025-10-08" version="1">MGPRSRACAAAAARTALLRRQLLSGRRPHCCAAAAASSLSLSHHRRYASTSTSPPRPIPKNVAVIGGGLTGLTTAYYLSMLLPATSHITLYEGSRRTGGWIDSKSKSEATKTTMRDITETEITADPTDILEAGARMVAPQRNVARYDDLLLLELIDQLELHDELRVSSWKPAQYVYYPDHLVEVSFTSGKPDPLKDQFEGPLDMVNMVQKLKYWGEMAGWALLSLKRILSEPLFLRLIPPVMYYMMPSTQKAEKIHARMIAANKAPGRYPPPSDDESVGAYITRLCDGDRSMADNLLSAVMHGIYGGDVWKISVASSIMRNQWLGEALMPLFALYNRQAKIAELRQQMAEANGRARPEDHDDWPGQNDGLGGGIAGHPPLTEETLRMAKVYSRAKGRLALAMESDTALLTDIMARQRERYERWLAVAERKRGLPGYEGDAGDGLPREPSPVDTLFKMAMNSSTWTQIGFAKGFGTLTDALTQHLRRKPNVTICPGEPVTSLKYEAKQKQVRVVTPRTKDKDGEVYDRVVSTLSSPALFRLAGGSATANVNGNVNGQLPSLKDAHAVTIMVVNLHYAEPHLHAPYRGFGYLIPQAVPLEQNPEGALGVIFDSDRELGLRRLVDLDRLIPMDDAHYQQVREASIRQIDADGDAMMKAERTRGSKYTVMLGGHYWDSYRYPDDFPSEEEAVQMAEAVLQRHLSSSFGWGGTTMPRPIATRAKLCRECIPQHYVGHAKRMAELDADLRREFGGRLTVAGGSFTATGPGVLPSVRSAYDVALRVAGRGYLIPKSQSSKNSRHETDMAHVGDTGLARFADPSTERVLPYDKADLPLRFGNKMMYGRGYFYIKPSNKNKVPIRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1N9</accession>
    <name>A0ABR3Z1N9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gastric mucin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14596">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14596:SF72">
        <property type="entry name" value="ZINC FINGER PROTEIN MSN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1455"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1156"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1476"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1514"/>
            <end position="1527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1546" mass="163005" checksum="5F4A52E9E9B504EA" modified="2025-10-08" version="1">MSQDGSLYSGSLVALEGLPEAALETQLRLLPGSSQILVLPSLQQYLDKDDELADPVAPSSSAPSATISSSLSKSALSTSVSPSGSRPLTTTAPFDARRYIRSIHNAAAARRAVALEFLQDKEASTTRTPPKKFVFLNGGTATSHALCIEAIRQHETAANGNLEQAALLFDQLTAHGVTGLDTTATSPAAAETSRLDDIAVDDDDDDVDGEHDPITKAMRAADALDRKTEGLQPSTHILDLTITKKPRPRSLSLPIHGDLLDLWDAGRRPSQMPTANTNNAAQNDNDNNNNNNNNNDDASTINNRSFYWVPPSMAAGASGSEIYDVNNFSFITPASPTRGGSPTSTIFPVSMRLDAIASQQQRKQQKKTPSTSPARQFVSYRSATTGETMRTVVLGPAPRGRTARRRPSHVDMVNNNDADGEEDDADDDKTFYLHRHQPQQRRARSLERKPSIGAGSLSGFSGFSGISSISGFSGFSGSSSGNGLGMNMNFFLSTSSREPSSTRPRRTSNVSDDVASMSTSVFGTKPSLSSSASSRIMFGGTNIPDVPLLPAADALEKMTLSKKKKAKSKQDVTTTVSASAPQKKTQLQLKTGASTTNISSNVDHGPGTEPVALNNDGIPVAFEAVLPLVEDLVIRFDDDGANVSSPALELAIQRCRELDGAQIITHQAPAINETVLSCQASNGKLSSFDQKTISSVLPETPKSSSHGHSSSSSTASASLLLGATTAAASAAPAASTFSTDDYDPFAPHEYNAGSKLPLSIAVPISVQPQTAPSIKTPQPLTPAHTPPPQQRPNEDDGLHDGSRFHVLSTAKYQTALALQNGIRSILDALFTDDQEDAEQKTVLDPLTTDSPTSFLFSCLPGMEGSNLWAPLLSGNRAGSKEDGKTATETPATDMVLAIGSQRGVPSSLLTKVTGQLDALSSQPATGIGRGGRLDIRYLIANAMQTLAAQQVCKYGKSTGTDVLATLVIAQLDLYLRTYPSSSLPVSSMRLVLLDYPMELLPVVLAIQQLAGRDMVQVASIIAVEDSKYRTESRRPGFQMLQQPLLSPKHKFSLPPVIGVAQNQSSFKRANFLLTSAANETDVEAFVASVRKIMLSSTKLVPSRATSPAEVAFQNGMIPLTLVAQQKSDMGRYSVLSTATTAAGGPGTGISSSSSSRNSKVRTPSRTDNLMQSPTLPSPLIGNTPSPKRRGSSSEKDRKRSTAENGNKTASRPPPLPLPVNTKKSVSSKVSTAPSISAVRPPKSPALSTLSLQSQQSQASSFQSFQSQADSWRTTAKTPSYITQATGLAPAPVVLPSGRLVAKTIQVNGPTVVRRAKEQTAVVLKPGSISGPVILNNLVAASTLSSSSIRSDNDNLSNWDAGLDVSEDGNYTYDDPPFGTSTSNGNGDAKGAAINTNAVPSNANGGSTGSVAFGGYNDDDYDYSDDDDDFENDLDMRRLMPLFMRDRAALLAAKEAAGSRGVRPPPIRSKSGQITGASTRAASASAAIPSSAQGPPQVMDNMTGGGLRGLRGKASLSSIHSQHSHGSSLTTKNGNEGKKALKWLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z264</accession>
    <name>A0ABR3Z264_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Negative regulator of the PHO system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PHO85_2</name>
        <name evidence="2" type="ORF">Sste5346_005664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="892" mass="94100" checksum="7D3750D1E622D94A" modified="2025-10-08" version="1">MDHDRERDRLVAALRHKLSELDARVVAYRRERADEFRRYAVDLLTPAADEAVVAAVAEAIEGKPDPKINLASKTDGKVAQTYPALFAGFLDNAGDDTGNHNRSILAPPPHARTLPRRTASPPPVLYHTSGVPKEGPRRPPTNNNAPEASPSLHARDDDFRGVFTPPFLPLLDSWSYDRRTSDTNTSSNKNDTSASDAATAAATVALDAATAKADAAEAAATKAAAENEAAETKAAETAAAEAEAAAAAAATPPPPPEPKLKSALRRTSSYSSSRSSTRSNTPTFNSPAANTSRPANTHHVRFSFNGEEVLPTASPPREHEQDLSWLMHDDRSNHSGGHSNIYDYSRHYHNATAGSGAFSSSGLDSSSSAHGNNLALGATALSAGPLSHSSLPGNEAEVGTAGPSSNSTSAAASTSTESAAGDQTTPLSQPSKNQPRNESHSTGDTFSSSSNPTSSTSNSHQTPPRPPQPRRRHSQILDDDEDEFVPLSRKVSSSDRLRALSKMPLEDPSMWTVVNPQADAAAAAAGNNTNDSAGSSAPTSNTDLAAATAVNRDNLVYQPSPAETSSSYRAQAPSPPTVEQREYADGNSYNSDASSDDDGFIAMRPSRGKSPISTAPAASTTPTTSTTPATTSATTTNGTASDGNSSRPKQSTSSDKVQVTYANTNGSSGRKKAAAAEDDDFFGFEADDMDGEDVGYPLSRVTDVNTHFDDDDDDVDIQDEDVDDEEANGDDGLVDDKDLVKKEKAALGIGTDGLDSMDLVINRHKPIVNNREGESALSSSLRRDGQLDGAGDEQPSSPGPASISVGSYRGKPIDLFNVVKDPRILQQAAQMGTLNSFVGSIHDHETYAPANMAEFSSLSGREQLNLLSGTPRSLTERMVMEDTRAFFSPSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z265</accession>
    <name>A0ABR3Z265_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005880</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF7">
        <property type="entry name" value="TRP-LIKE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046695907" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="33"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="60"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="588"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="666"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="793"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="669"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="851"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="879" mass="94120" checksum="8F42861D6731B50D" modified="2025-10-08" version="1">MAHSFTRSRQRFSDLSLLSLAALFLSGHHVVADAVSRETAYVYGTDSHGVTRQLAADRTPALYTSDFGDCLGGKSFFNISAFDAAYYADNMTVVFHLDGTSNVHNESTMRNGHNNGSILPLTIYGAFALVPMQTASIPDIALQIPDFDGSVSLQIFANSTQSEIGCFQAAMTNGNSIGIPEILAPTIAFFVGIAMLCSFMTAAYSISVPLMRAHYAHSLSVVLMFETMQTFFLTGALSLHWPSVLVAWWSNFAWSAGIIDITPLVAQIGGFSGVAGNISQFSDDGPMFVKGGSGQLADQIYSSDGTNNGPVLAAVVSLLKRKVYNSSDPYDYTWGGDPVLPGVPLPGTWQSLSGTLGNLNIPGASAFTLCLFWMVIASVVFPLGLLGSDDNIEPRGRPFVHQDEVYIKKFGWLSARYKAGCYWFFAVQLVTQFARACILGGGADNESVVDPSHKTITGTAGPTAQLVILLLFEIAVLTIYAYWQPFESSRNAVLSVWILGVGRILVAALCIGLLPQIGISRIGATVIGFAIIVVQVLMLAVVLVLVAISAVSTWLSLTRNQDDFYSEMFFSVRKRYLETLLASATGAPAPLTRRQEKKQAKANRRADREAEKLAASMTPPAPSFSVFDVRRAPKIEDIHYANDNDSDGDSDVEAFGVHDVMFFRRNIDSSGPSPSGRSGRSGSSSRGGSDTTGLATDRDGEIDLDTLGALGDLGPLNTRRRRDTGSAASLVGAQIYDPARVIARLNRSRTSSAASLRSVPSAHDSIRRVSEMTAQSGPLPGPPQIGILAGRRSASPFGGAGGRASPYDMRSSSVPPVFRGESPGVSVSMMPSGRGTPNSLAGPVSRRMTPTKETLQRYSTERQSLQSLRSTPVPYPVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C4</accession>
    <name>A0ABR3Z2C4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="10">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Biosynthesis of nicotinic acid protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">BNA4</name>
        <name evidence="13" type="ORF">Sste5346_005836</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="2 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="8"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="538" mass="59912" checksum="02341F46DC0EFAC0" modified="2025-10-08" version="1">MAETVRQKTVIVGAGPVGSLAALYAAQRGHEVEVYELRNDLRDPSTTPLNFTKSINLALSTRGITALENSGNVELLEHVFDATIPMRGRMIHGKKPTGELYEAAQDYDAHGRTIFAIDRAGLNGRLLDILEKLPNVRFFFNHKMTGADFRNRKAWFELQDGPKDGPNKKTGRAREIEIGFDFMIGADGAHSPVRHHLMKYVMMDYQQHYIDTLWCEFQIKAAEVDAAVANDADTDAAFRAKFRISPNHLHIWPGKDFMFIAIPSDDGSFTCTLFMPTAEFAQLETVPADDDKTLPAFFNQHFPGVTELIPPADLVASFRRNPHLPLISVNCKPHHFQASAVIVGDAAHAMVPFYGQGMNAGLEDVRVLFGLLDKYANAESNDPSGDVDNSAASVDARRSQALAEYSALRVPDAYAINDLALHNYTEMRASVLSPTYRLRKFLEEQLSVHVPWLGWRTKYARVSFGNERYSEVVRKSEFQGRVLLGGLIGLVGVPVFTGLVLLLHGRGRHGSGSCGSFFRFVTSHTRYLAQWVANGFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D3</accession>
    <name>A0ABR3Z2D3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF30">
        <property type="entry name" value="XENOBIOTIC COMPOUND MONOOXYGENASE, DSZA FAMILY (AFU_ORTHOLOGUE AFUA_6G01920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="2">
        <location>
            <begin position="33"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="493" mass="54390" checksum="00245C40728602FF" modified="2025-10-08" version="1">MGSVEKKQKQVHINFFETACRGNHEAAGQWARPGDNSYQKDSLEYYINIAKLADKNKVACIFFADSYGSHSVYGGNQDAVLRAGTQVAKLDPLVIISAMAAVTESVAFGVTGSTSYIEPYPLARTFSSLDHLTKGRIAWNVVTSWSGAAAKAFGRELLPHDLRYEIADEYMDLVYRMWNGSWADDSIKWDTKSRIAYEPSRIVSIEHEGPHFKLSARGPLHPSPQRTPVIFQAGTSKVGQEFSAKHAEAVYIGGLIPSQATGQIKTARDICRRNGRDPYSIKFFAAINPILGRTLEEAQAKYAEACEYADVIGALAQFSGYTSIDISAYPLDEELKLDTSNPKAGAIQGFLGNFRDSQADGDVWTPRKLGQKIAVGGFHPTPVGTPEMVADIMQQWIDEADVDGFNMAYISNPGSFEDICELLLPELRRRGMVFEDYAVPGGTFRENLMREPGQTTLRPDHYGSTFKFEGEVPYVPKGPDGKPLAKEETKVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2H7</accession>
    <name>A0ABR3Z2H7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="618" mass="66383" checksum="72C809FC9C713658" modified="2025-10-08" version="1">MANVTAAPVVSWLHAYPPLPILASAAMAQPAGRLLGVSAVSSIWLRASPVVCALDALSVIVRCLVYCVLLRATPRQALVLVGTERFSDADTSDDASPSSTERGTTSRITAVAKATISMIIRLAGFALGIVPLVELIWFEPGGQDARWTAAWAWMFVAAYVLLEVVAAVYRWEQAQPQYTAADFELGEVEGLQGTIVAGSGENGMPYDGVSSRGSEEAPRESDERTVVNDDGNKVEDEDEDEDHQVDDAETADLLARGGERSDTAATTETPAGTTGAAADLEANSDKAHPYEYNNDPSSHPRLPAINAKFSTIESYVVGIGWLAHGLFLYWAFLDLIQPELNAHILQVDVTKNGGWEMVSRLSFSLYYLSLPFVFAALILVMALTLGAGALVAFIMLGFAKFVTSQLPPSVENWAGGLVPVVITGGCAILGGLATIVSFFMGSPWLGEYLLSSHSMWIYETITLELIVFILYMGACFTFYAVLKGLTGIFKNKYSQPDPAAPAPNTTRSTFNPRPSSSNPNPIAKDDAPKWAANLVVYTSDDSVALIAMALHTLLISWLWYAIRFAESSHWRQHWSDALIANVTTPHNGTMNGTANATASFAASIVASITPSSTPVQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Y1</accession>
    <name>A0ABR3Z3Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="30309" checksum="6B5A772ECC9100C7" modified="2025-10-08" version="1">MASYPTTTPPPATPVFLKLSFPAPRVLLVRMDRPRDLNAMPTIGQIEMNEVWKWFDDEPNLTVAIITGTGRAFSAGADLKEWNRSMAPDADPSKRMGNAPAFKPLSRRLGKKPVIAAVNGLAMGGGCEFIVNCDLVVAADDAYFALPEVKRGIAAIGGALPRLIRTVGLQRATEMALTGRNVSAQEMQTWGVVNSIVPKDKVVEEAVRYAEMIAQHSPDAIICSRAGIRQGWETAPVERAVEITLEREFAELQKGENILEGLAAFTEKRAPQWKASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z477</accession>
    <name>A0ABR3Z477_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CYP10</name>
        <name evidence="8" type="ORF">Sste5346_005483</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="6"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="200" mass="21310" checksum="1C4E94416E937D80" modified="2025-10-08" version="1">MSVTLHTNVGDLKIEVFCESVPKTAENFLALCASGYYDGSPFHRVVAGFMAQTGMPASASEKSKDKSKEKDKGTSIWGQPFEDEIRMPALRHHARGIVSMANKGAPPVGSGLSGTNGSQFFVTFARTPHLDGVNTVFGRLLGEASFETLDKIEACPVDKKHRPKSGPPPAKGEEGESSSSSSSEPPKIVRVTVHANPLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4J5</accession>
    <name>A0ABR3Z4J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="142"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="446" mass="49765" checksum="D0455CCCA784A8A3" modified="2025-10-08" version="1">MDWFGRASVEFTHSASPLQLALKGVNKNKNGSSNGAASSPSQTTDLATLCRDSTPVCQLNPLLFNGHLQTMWTAVAKGAPEIYYKRRIFEADHKLYTGSFAVDFAVPPYEDQHRPEDAALPPRTSYFDEDGFKNIGSSDTRPMLLVLHGLSGGSYEVYLRHCLAPLLDADDLPWEIAVVNARGCAGSEITSGVLFNARATWDVRQVAQWARATFPNRPLFGLGFSLGANILTNYVGEEGANCPLKAAIVVGNPFDLQVSNKFLQSNFMGRNLYETVMGSNMKKLINRHREAILEHTDLDLDRINQIKTLYEFDREVQCPTWGYPTEEAYYRDASSCDSLLNIRIPFMALQAKDDPIAVAEAVPYGEFKHNPYTVLCMTSLGGHLSWFEPGGGRWHAKPVSQFLHKMAVEVDLDAIPRDLHDVNTKQRKGVNYSPLRRKMEINLDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5B2</accession>
    <name>A0ABR3Z5B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005248</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF316">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045280815" description="FAD-binding domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="6"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="424" mass="46426" checksum="CB1D830271DDAF4D" modified="2025-10-08" version="1">MSTEHNVAIIGAGLSGLTLALALHQQGIKSTIYESRPAPLNIGGAVMLSPNALRVLDALDVYSVVKPQGYSFERLDFRDSDGNVTEMYEFGDVSKYGYQGLRIYRHVLIDTLVAALKKISVDVVYGRKYSHVVSEDEAANTSGGVTFAFADGTTETASLLVGADGIHSTVRRHLYPDLETKFLGMAGITAAVPTAQLKLPADGSYHIPVTIASKNKERGGAFVIAPQNPDGGEVLIGKQRRIQEHERAAWEQRGSLADGRAAAVAFLQEDADNYPDIVANAVATIDPAKINVWPFYVVPKLDRWASATRRVILLGDAAHAIPPSAGQGINQAFEDVYMLALLLGRQWNTTDVADPQAALDFWQSYRQARIDNVFALNHQIDLRRMPATDAAFVTGDARQPFDLTWLYKPDFKKDVEDWVAQQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5R3</accession>
    <name>A0ABR3Z5R3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045713577" description="DUF7580 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7580" evidence="3">
        <location>
            <begin position="181"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="587" mass="65305" checksum="972EB2041E73F46B" modified="2025-10-08" version="1">MAEVAGLVLGGIPLVISAVELIAEPLESYKDYHMNVLIFHSCLKIQKQKLEVTLSNIGLDRPTKDELRECINTKFPTIADEILYIYECIEKEMVKLMRKLGIDPHTKIGSILRASPADPKRIWNAISSRRRKATIRLLKELNEQLCDCLQMETSEMKAEDDDVVVLSLIKRFNIKHCDALRLCLASLHRALASGLVCACEVPHHAALDLDWHLDRSAMSPDLTIAFSYQDLRNTSAPCWRKLLATPSVTRPENTAQPSMAAQSMPSARASSVAPPTTPPRTPSPLRFWPSFWPSRAKVGQRGSSKQLSLLVPQPAVDDPAALVNLCEVLSSDITSEHVLQDDDEDHGRDFSLQLQQHKNVGEGRGEARITHLVPLTKALDPPQSHQRLSLKARCGLAACAALSVLHLSGGPWLSKDWDGSCVGIFFEKVENNAERLADRPWFLYNSLPLPWTCLDDDGDNHEADDAADDDQVTNLVCQDDHEKLLVPNITVFALGILLVELCVGKSFAPGTPVTATTIKARYEFAMSNLDKVYELAGDSYGDAAKKCIRFSFPGRDSHNIFEMEQFRTMFYRQVVAPIQAAYSKFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5T9</accession>
    <name>A0ABR3Z5T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005246</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045208250" description="Chitin-binding type-1 domain-containing protein" evidence="11">
        <location>
            <begin position="26"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="12">
        <location>
            <begin position="238"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="137"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="367"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="181"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="49307" checksum="465A617C705F81D9" modified="2025-10-08" version="1">MRTPATTVALVAAQLLAFFGPLVTADLPTDSDATVSSIWVVPDATEDAFNLTLVAGDSLQVAWSGTDGLTGDTTADLWVAAYAYSTSDTFSQLLTKNVDLSVDGTFNWTVAIPQPQLDATPHYVLTFKTARDDFQFNASDPGLPSPGISVIENHDDGLAEDSNSSGSVLTSADGSTVFDSGDGDDDDDDDDDGDSDYGDDDDDDDGDGDDYGDSSSSNSTSTASASASPSEALTITTNATCGGSFTCIGSTFGDCCSQHNFCGSTIDYCGAGCLSDFGTCDETTSTGDSGGKPLSVAATAGIASGVSVSVVGLSVVAFFWFRRHRSEAGRRKSQEQQMGGGGNGNYLGDGSSAVFYNGAGRGQKPYLMLETGRNGPMPNNGSPLTPGKSIYTGYTSPDSTHQPEYYNMATIQRPPTSSTTAAGTPHPGSVSTTSIQPPLPHQRTGQQSGVFEMEGGEHPYHYGQTPPAELDGTSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Y4</accession>
    <name>A0ABR3Z6Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36209" checksum="F0917EE4743BDFD0" modified="2025-10-08" version="1">MTGAENLTVAPPPAMPVKAEATTELKSPASPLPTVQEFDANTCSVDDLVVALKTAGGVVIRNLLTPQALGAIEADVRPWLEKDKPWNGDFFPPETRRVTGLLTKSETFALDLVGHKLWIGVVDALLTSEFPRNWVGDKQEASVGKPQLNNTIVFSIGPGARDQALHRDDQIHQVSHRAVAAHEMGRDYGIGFFVAGKPTTKANGATRFIPGSHLWDYEEGPPREDQAFYAELGAGDGFMMLSGCFHGGSANKTVDQERLVYSCFFTRSWLRQEENQYLIHDLEKLRKLPLWLIERAGWSLSPPFLGWTSLEDPIAHLFPEKAGSKDMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z866</accession>
    <name>A0ABR3Z866_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF2">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="94"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="191" mass="20625" checksum="C99B7172692A8201" modified="2025-10-08" version="1">MTSSSSNGQLSAPSLSQQKVLVTSHNADAKAIVHSAEDFQWQPYDGNQMAFSVLFSTSQFPADLNNNADIASHEKLLQSNTGLVSPNGTILRCVDFAPGYKCGMHRTQSLDYGIVMAGDIDMILDSGEVHHLKAGDVAVQRATNHQWANTSDTEWARMMFVLQGCAPLTVGEKTLGEDLGEDLAFLPGSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Z4</accession>
    <name>A0ABR3Z8Z4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="873"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1057" mass="112391" checksum="52385DEBA45C03DF" modified="2025-10-08" version="1">MGLCFCHRASMSLSPPGVDARHPMPLNLSALPAAPRPAKLARPGASDTALSSVPPSTPPPRSSRQRGVTAAESPRQGSGRCPIPKIPDFEGLADSETDSDDELLSHARMRAAGLSASPVPSTPVKLSPGGGVGGNDGTGMSPLTSLISRIGIIGRSSPVRPVTQGRTPESSCSTDDLVAAARRAQVRRLTQKMIQEELQSEQLQQQQKSHHHQPQQYISRSYKRSSMSTIKEDPADISAHDLGHPYNTVSIMDGSSYRTSLEYTFTQSREDLSVPSSLYSKGKEAGTYLLPKPPMLSPSVSSRHSAAQAGKASLPQGIAVRGRPRGGVQGKGPKNSIWASFATDPSARRPLPESASPFAHSATSAPKQAAKTTTGVATKTVSSSIHEAEPQSSLRVKHFASNGQMQGDRKNEKQGTVAHSQSQAVSDSLSSVDEDGSIHEARKARVVVSGQLRSSSNRLDNIVDVVTTADNAGAPQRTSSPLVTAVTKFKKSSRRKTSESSHISSLDLPPPLVNILLGSGDTANADTQPTCIAGTDNTATPGPPSHNGLKRLPFLSLDRFGFGLRKSSNTDLPAQKSASAEESKLSASLRNTVSGSVASLGVQLDGQIMDGSGRNDRDSESDKSQYHSMTSATLKVWAEDSPPTQSELKSGVYGSSQAAARATTTDIEIMAEEWHQQIQRLDRNSPYLSDSWWSEPKWQEPEPKEAPSGHEAVDPIPTTKATEKDLPNEKEVVSPLSPIKSENTVVHNEAPSPEPEPSYSRVFSSGIEKAIRAGFKKVMYRKQASTPSLAAAAAVPAAAASSRSLNPQPSTTASHSKASSLNVEKGTPASRAAAPVLESRPQETASESPQTPRHKDDDLIQDIDSIFGVLVNMESNQRSTPVTPVRSQQNKVDKGSALLESENEVVSPQTVPSTPIANAYAEVRAYISAVLPGTPARRVGVQDLHNSPISPYQEAASHQGSDAVCATTQANVKVASHKSLDSMSVKSDSVPVKKAAEADNSSNKYMTWNGSTVPKATVPVLKSTTQFSTDLENIFLGKKENRKAFQDHTLQPAVEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q1</accession>
    <name>A0ABR3Z9Q1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol transfer protein (PITP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PDR16</name>
        <name evidence="3" type="ORF">Sste5346_004134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="123"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="390" mass="43225" checksum="4436846837ED584A" modified="2025-10-08" version="1">MGSPETQSEKDGSASAGILKLPIPQPTADSVPPPRAELTADQATKYEWLLEQVQSWTTVAASKDSKEDKSGPLTDDDRFWLTRECLLRYLRATKWHEKDAAKRLMETLSWRREYGVDALTAHHISPENETGKQVLLGYDKQGRVCHYLNPGRQNTDPSPRQVQHLVYMVERVIDIMPAGQETLALLINFKTSKSRTNTAPGISTGREVLHILQTHYPERLGRALIINVPWVVWGFFKLITPFIDPLTREKLKFNEDMNQYVPAEQLWTEFLGKLEFDYDHDVYWPALTKLAAERRAERLARWEAGGKQIGELEDFLAGKLAQGVKPAEGVVAAAPVAAAPAETATPAAPAAVETGETTANTSVEDLKVADLKVTDETPAAATETQTATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA10</accession>
    <name>A0ABR3ZA10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exosome non-catalytic core subunit rrp40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRP40</name>
        <name evidence="7" type="ORF">Sste5346_004744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22526">
        <property type="entry name" value="KH-I_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049469">
        <property type="entry name" value="RRP40_KH-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041054">
        <property type="entry name" value="Rrp40_N_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18311">
        <property type="entry name" value="Rrp40_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21262">
        <property type="entry name" value="RRP40_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exosome complex exonuclease Rrp40 N-terminal" evidence="6">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="171"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="27461" checksum="45D4AC9970C4D72B" modified="2025-10-08" version="1">MSAPTQIVLPGDDVDPTELLPPRPATGNDKKSKNPPPLRLGPGLRLLLPSGEVVPTVRGELVADRRKNLLWVESEGGRYYPTTGDLVIGQVIRTTADDAIVALAPHDAPPLRAVLPVLSFAGATRKNRPDLHSGTLVYARVSLAAKHLDTELECVDQNTGKSEGLGPLIGGMVFPVSLLMARRLLIASTEKSGLAVLDALGEEGLPFETAVGRNGRLWVNSDSTRTVVLVGRAITATDSQNLDVQQQRALVKKLVRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAH8</accession>
    <name>A0ABR3ZAH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Triosephosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="276" mass="28792" checksum="DAE2B48E1CD3B930" modified="2025-10-08" version="1">MAPASDKRRPILGVSTKMYFTLSKTRSYVDELLTLLAADDNKSITDKIDLFVCPDTLSLPSVVEQVHSAGLPLLPGAQDCADTDYGAFTGFTSPAVLADVGARLVEVGHAERRRLLGETDATTAAKAKAAVKNGLIPLVCVGEIAAPESDATEEEGFRGAAAAAASTVIAQIAPVLESVPDDAEVLLAYEPVWAIGAAQPASAAYVRAVVSCIRDKSPAIQRRGAARTRILYGGSAGPGLFEQLGGAVDGLFLGRFGHDPKQFLKTAHEVAGTSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBB9</accession>
    <name>A0ABR3ZBB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GCD7</name>
        <name evidence="11" type="ORF">Sste5346_004169</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="entry name" value="translation initiation factor eif-2b, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="442" mass="46792" checksum="26C2C3D22CAA600C" modified="2025-10-08" version="1">MAPTQHGYAPTLDSFLHAKLHLEAAVEQACSLLKRRQIRGPESCALVTAHVLSLVVSKAKWADVDQLLDRVYQAGRKLVDAQPQELVIGNIVRRVLGLIHDEAEADRTENGEEAPSIPGSMSNSISDLRDPSQLAPSPPNLMTSPSYTALARTTRQPSLIATGPYQSMFNLLSAAEPASFSASGEVSSAGSGASTPVPTHGAKAESGRVAALRDEILDGIEEIKDEIGQADDQIAGFAEGQIRPGDTVMVGAEPSRTVEKFLIKAAARRRYTLYLVGAIAPSASGSSTLYKRLGAAKCPVVHLSNTAVSAYMPRVNRVVIDAHAIAANGGILAGAGSGRLARAARAQGRTVLVVGGVYKLSPEPLTNPDAFIEWGEPGQLARFADGSLVGDGGLAIETAVTEFIPASQIDIYVTNLGPHSKDYLESVIADHYKNEELELYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBL2</accession>
    <name>A0ABR3ZBL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF5672 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043729">
        <property type="entry name" value="DUF5672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18922">
        <property type="entry name" value="DUF5672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5672" evidence="3">
        <location>
            <begin position="135"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="400" mass="44788" checksum="169701B75886C601" modified="2025-10-08" version="1">MAQQHNQQSVFAITKGKMFILASLVFTWWVAHLLPHYEPMIRSHISDRLQEARQKIPSIKVDWRIPEEPETMFNASKVALIIEPRPLPHLVPLVLHMATVVPPDWRFIFIGSEKSVFSVSRAHAIKHQQVIGKLDLMVLPEPWDISSKEMVFRMLTDIRFYDEFLPGVEWILKYESDSILCGNSPTSLNSWLDWAWAGAPRSADDRFSGNGGLSLRKVSAIRRILRFQARYNNSEPEDEWFGRRLWVLPGEKVTSGLTALAVENVYVENPMGFHIPDSGKNLPDEVWKNPEQRKKIFDYCPELSLIMDMKLERERCDGDDKMGNIVPSRQDLEKERKASIASVSKASAASVASVASVESAASVAAKATDASAAPSDSVLLTAPPQTASKSAAAEATPARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBT5</accession>
    <name>A0ABR3ZBT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF2">
        <property type="entry name" value="GDSL-LIKE LIPASE_ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046108138" description="SGNH hydrolase-type esterase domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="231"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="424" mass="44263" checksum="C93AB24A46FCB5E3" modified="2025-10-08" version="1">MAPSSFVELCSSFLLPLLILGSPASAVPTSVAAGLSAAIEARADDGHWVDTWTSMPQLVEQSNMPPSAFTGGGATFKDATIRQTVHISIGAPRIRVQLSNTFGGSDLPITSASIALPADGKVGSNAIDPATLAGLTFGGKPGITVPKGQIAYSDPIDYKVGPQSMLAVNLYLQGGQSGSSITGHPGSRTSTWMQSGDHLNATTVTGSSTKHWYYVNAVEAWAPANTSALIILGDSITDGRGSTDDANNRWPDLVLAKLQKAGITNLGINNEAAGGNCVLNGGLGPPLMQRYKRDALQQQGVKYVFIFEGVNDIGANANGDSIISAFKTIIADCKAAGLKVYGATITPFGGNSYAGGNHEANRKKVNDWILTSGAYDGTVDFAKLLADPSNPEKLASKYDSGDHLHPNVAGYQYLADNFPTDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC73</accession>
    <name>A0ABR3ZC73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41390">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41390:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 213 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="177" mass="18546" checksum="28C7161CEC8BD28C" modified="2025-10-08" version="1">MSQPEATPPARRPPAPKAQIPPELAEILAPSLQVGLGAGSRSAIVHHWGGESKLTSSDKVKASTLAGASAGLVGGALRGPRNILPAIAVFSIFGATGQAVVNALPSGAAPDDSNSKSSWLDSRWSPVTPMTDTEYATFIEDKILKLDVEVSMIDDQLAALRERKAQRDAQEPRQEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCJ3</accession>
    <name>A0ABR3ZCJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Autophagy-related protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATG11</name>
        <name evidence="12" type="ORF">Sste5346_003719</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Preautophagosomal structure membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="7">During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATG11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040040">
        <property type="entry name" value="ATG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019460">
        <property type="entry name" value="Atg11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222:SF1">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10377">
        <property type="entry name" value="ATG11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="10">
        <location>
            <begin position="110"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy-related protein 11 C-terminal" evidence="11">
        <location>
            <begin position="1141"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="597"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="663"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1080"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1321"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1413"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="880"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1147"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="630"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="663"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1090"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1340"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1413"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1438"/>
            <end position="1453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1460" mass="160998" checksum="BABB4C02173351F1" modified="2025-10-08" version="1">MANEVLIAHTGQRLHVDFSQILSLDEFRTIVNRQTSIPTEYIIALTPQGKPLRLAAFQTEKEIYVYDARTTLSQSDAASAAAIANLEIPLPSKRYTFSNPPNDLRDQRSLSAWQDLFAARQKWATAVADDCASKAGAAQERYAEMDAMMRCLDAAVANLEAVVRGTEGKYTEIRKWLDSARVDYADLVGRWEHYLELARSVSISPSMLRFMTGQTSQQSSSNGRSKQNATLEDLVDLETARKAGKLAPAALRRFTTKIDELERDAPQLLRGCDEVLQNFERAVDRSALSHEGETAQLLDDIKAVANKIGTDYQTTLDFVSDSTRDVLQASKIAATHTERLLPSIKNRAAEMDEMFRYATQSRNALAVETVEFMRNITDLTSLSGSIKAQIAAVSSNNEDDMAHFDYLRLVQQIPYVYASFVSEAIKRREWLDKVKTDSSTLANEMALFHDEEVKRRKKWQKSVGNLAYGPSVTSAENQVAGLEVNLLGEEADWPNVSRKDLEDLYDILQQQKADGALINDIGKLTSELNAPTKQQSKRIKAFKNGSVHEVALGRSGLLVRGDDDVLRRLQEDKAKTENKLRTAESRVRRLEDLLHRQSQASRSSLGGIFQPTPSQQFSVSDRADRDRAESTASVKPGTTATSNGGEARIAQLEAELAAEKARSAAFEKDLQSRTEEHTKTVDQMAGQMDETNSTKNDLLENLEALKKEFTEERKSLEDEIKRLQARLEDTEDEMEHFGESRENEKATLDEKLRLAQEEVERLERQNKSYRDDALKTQGQVDFLRKETKLQREQNESLEKQVQAAHDEAQSTTKHLQDANEAEEILSKGFRDLFVQLVASEGGGSQSKITSPPPDTADLIETVSGKLADALARVQTTIGDMVIVRADLERAEAANQDLQAKMVLSKETLATEETAARRLREKMAEDMARIATLEDELGESRTDLNQLRAKIADGETGSETLRKRLEEEERKVVSLTEEVVAKQSHLGGVEEELRMFREKHSDAQAALASLTARFDARTLRAKDLSQRLYTQNDRLCRLLERLGFSVTRNGDSMVITKIPRSERSTIISGEGASSLLRRSSGMLQPARPGESTAAPATSSTSSSGADVQLLYWMNSADGETETAQYAEFMASVGSFDIDAVAETVYRRVKEVEHIARKMQRDVRSYREKAHTLQKEAHDKIAFKHFKEGDLALFLPTRNQTSGAWAAFNIGFPHYFLREQEAHRLQNREWLVARIGRVQEKVVDLSKSLQQQNRGETASVNTVDNDDNPFDLSDGLRWYLIDAVEDKPGAPSTPGLGKSTVAANHVEAIADIHTHARTASAGHRTLGLGLGGGRPTGIDGVSKTLSRSLESRRSSTSSRKAAPLHAAAGNAAALRGTAVASETNSLRAAPADTPEHGTSPTSAPVVLAAAATATPSTVITPAANDANDAPNTSEVRKPDSSSSPTTAAADTSAATVDSLLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCV7</accession>
    <name>A0ABR3ZCV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="360" mass="38375" checksum="72FACF4EABD8E125" modified="2025-10-08" version="1">MSAQLWDMSNTITITRNDSNSVLEGVTFPQSSSQSMASSGITTGTHDSTQGNTHSGGQSPAGSTHDLYFPMDALFAVSRNFIQTIQIACHGQKDDSGPTSGNGVGTTNMEGASSDRVDAESFIVLADSTYAALLDVYQRVFHLVEVTANNERPTLSSHNGNNNGSNHFMRASKGDLKHSARFASGPSSSWKDSAALSCLRVCRFPDVSVGGFPIVSTPALQLGLGLRLADDFLSHFSSVVVTMHNCFPPARRGENVAVSAPAEQQQQQQQHPLPTVSTNCLPHPPLVISEDLFAIDGFGAPMDWDASTATSVSSSSGTSSLFSLQYGLGMHRSPSSMDDIVLREHDLRQELAGLRNKLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD06</accession>
    <name>A0ABR3ZD06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047444204" description="Thioredoxin domain-containing protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="22"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="293"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="777" mass="86921" checksum="F89D8683D82B0DF3" modified="2025-10-08" version="1">MRLSSILPFLGVAAVTVAAADTKAEANADDGDKPTTFDGIEVPPLINLTPKNFDEHLNSTKYLYVKHYSPYCHHCKKFAPAFQTTYEYYYTEKVEGRTTPSAEHYGITFAQINCVAYFDLCFKHGIQSYPTTILYGDRKKIVDIKGVKNGTILAHHLEGALDRDFPGERPAILYLPAEGETVHPRGKEDAGQILDKAAIAAADKAKAEKAKANKDKAKSGSNKEDKKADVPAAEEKPKEATEVKAEAEAPKEASGAPAIVAAAPEDTTEKTIEAKDTGAVPANEKKGSGKPKKKTPPPAPLYRGPPKPTTPQNPNGASVPLTAETFQTAVTMTQDTWFIKFYAPWCHHCKAMAANWEQLAKEMEGKLNIGEVNCEKESRLCKDVRVHAYPTIVLFRGGERVDYEGLRGLGDFVSYANKALDVVAGVQDVDAASFEALEAKEEVIFVYFYDFATTSEDFMALERLPLSLIGHAKLVKTNDPALYERFKITTWPRMLVSREGRPTYYPPLTPHEMRDTHRVLKWMKSVWLPIVPELTASNAREIMDGKLVVLGILKREDKESFAIATREMKSAASEWMDKQIQLFQLERQELRDAKQLRIEEAEDRNDQRALRAAKSIRVNMDRADKKEVTFAWVDGAFWQRWVRTTYGVDIKEGERVIINDEDNRRYWDITSTGNPILPSRTSILETLNKITQSPPKIKPKLTISAIEKLFFDIRMTFSEHPYLSTGCVLGMSLGIASWLRGRIRRNGGGRGHFRLDEVKDYKLPMLGSGVNPAGKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDL6</accession>
    <name>A0ABR3ZDL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="110" mass="13277" checksum="F43994CF0FE761E9" modified="2025-10-08" version="1">MCYFEQTRWACGYWKWGNFRQQCPKEYRTGETCGLKLVYATVYRNETCKLCDQIEKKNRRLEKLQRDVERWQHEGNRPATIEKTQNDINEIAERVNRLYQDHVGRQASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEB2</accession>
    <name>A0ABR3ZEB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="99" mass="11142" checksum="8DB400953D3B035D" modified="2025-10-08" version="1">MVDWDIGMIPDNAIPVQSFLVTLRLYETKRVDDPATGKIRLADTNVKHLKAKGKTDTELLSWAEVSQNYLVNSSQPRMQTMLSKSPKESMAKEGYQLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEP3</accession>
    <name>A0ABR3ZEP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="415" mass="45169" checksum="4EBC9561B732551C" modified="2025-10-08" version="1">MDPVSPPETPITASPGRRPAAGLHSQPLNVRHSLSSSPRFSGASGRDLRFSVSPGAAGANGIPFRTTPFRPDELSPRSAGSSINGIPSINLATKVEDADDDADDDDDIESDSDSDSVASGSISKSSSSAELSSPPITSRPAPLRRRAGQTSGSASPAYTPGGSRTKSNSSRRASMGRDPTQSSTRLLFVEAAALIIEEVSDFDSDNGRVQVILPYEIEEAESEREKTPDPNQNRSGKFNMGRAPRRRSSARLSRLPEIDRSVMSGLRGFSFRGDSDEEALIDEDDEDGSDFDEAAYNLFRLKQRADRRRRRMTSGSISKRTISESIGSDTDNEDLSATLDASEVGSSARRLRRRIGDRHSLQFQDPPPPRIDELEEPDTSDNEDDVKELTRDGEALARELPYYTLEYISMEVDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF13</accession>
    <name>A0ABR3ZF13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ketol-acid reductoisomerase, mitochondrial</fullName>
            <ecNumber evidence="9">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Acetohydroxy-acid reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ILV5</name>
        <name evidence="13" type="ORF">Sste5346_003189</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016207">
        <property type="entry name" value="KetolA_reductoisomerase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000119">
        <property type="entry name" value="Ilv5_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="11">
        <location>
            <begin position="65"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="12">
        <location>
            <begin position="255"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="404" mass="45123" checksum="31F1B07D30DC0F21" modified="2025-10-08" version="1">MASRGFSRALRSPLARQVVAPAQRRTFVAAAGLVRAKAAVSAVMPAKIAQQQVRGVKTIDFAGSEEQVWEREDWPKEKLLDYFKDDTFALIGYGSQGHGQGLNLRDNGVNVIIGVRKDGKSWKDAVQDGWVPGKNLFEVDEAISRGSIIMNLLSDAAQSETWPHIKPQLTKGKTLYFSHGFSPVFKDLTKVDVPKDIDVILVAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAEEKAQAIGVAIGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMYEACSTTARRGAIDWSPRFKDALKPVFNQLYDSVHDGTETQRSLDYNSQKDYREKYEAEMEEIRNLEIWRAGKAVRSLRPENQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGC5</accession>
    <name>A0ABR3ZGC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="37324" checksum="67A1030D994393B2" modified="2025-10-08" version="1">MADLRRTRRQEMLGRLERFVGEAEVYLYDAADMLGWSFQNLVNPPSRAANWLQWHIAQVRTSIVETVWPWAQNVGTRLSEMINETTAERNTARAGNCNNDAPSQLAQPAQPAQPQPEGPVPVNRSNLTDLDLLSLLSSDSAFDSLPVWVDEDNDEGNANINFDDDADDERNDNSLLRSQPSNFDGAQTALLTEENLSCFLAAIAEKDARDKAVSSAAANAASHGSSKDNNAGRSEYASTNYDPSSENNVAKNVASRTGENSHPARNPNYAQSWPPMPSRRSRQRMNQTLSKATTELGSQASVNGPTQLPSADPACSVGSVGSSAILVNPSDAESDEEDHYFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGM2</accession>
    <name>A0ABR3ZGM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1365 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973:SF4">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="43973" checksum="A1BA0B14E50A14D5" modified="2025-10-08" version="1">MALYLVKFDQLITAALALVALAVVIFVIKTESTNKQRQAEAEPWTGPGKPLLFPCITTHTRLVPKQHSFVYSYLVVGVPVGWTGVCGGMISVATDSPTAERKEIKKGWYHIDAEDYLERGYGDLGLCGKLDSFLKSERIEPEQYPHAYFVTAAKFLGYHFNPISFWYLYDTEKQLKAIVLEVNNTFGERRMYYLPLVLTERNGEESSKKGTLLFKQAWPKDFHVSPFNSRKGSYELLANDPLAPNMQGAGPIAVTVVLRTSDKDSKLVARLFTERQEKKTEAGATTAIHSLDPAVMSLWQKTKFLAAWWWVGFATFPRIVKHAGILFFRKRLHVWFRPEPLAESMSRSADSTETMLESAFSLYLQHLVSNVNDKEDEAGSNKPLACHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGZ0</accession>
    <name>A0ABR3ZGZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDC37</name>
        <name evidence="10" type="ORF">Sste5346_002860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="8">
        <location>
            <begin position="219"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="7">
        <location>
            <begin position="400"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="482"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="56514" checksum="B0298503AF0A3E01" modified="2025-10-08" version="1">MPVDYSKWDNLELSDDSDIEVHPNVDKRSFIRAKQSQIHQERQQRRHQIETLKYERQVNDGLTKRIGSLLNALKAHDEEAKAAGSSPTAKSAGEVAFRAVMTDAASLKPEDDKPPQPPAEVHSNVDQNTTYTQMMAALLDQVNKALEEKKVEGPARYEAMVAEIEEHQNKVADLQRQLVEKLGELEKEESRKITSDTFHTGFDSSHVNKSQPSEGANTSGSGTGKPELLNPSYKSADAAAASSSSSSKPSADDDNDDPSEPTPLARKFAAIAPNNHLESKSFIAANPQVLAEKHEEGILMLAFDAEMEGQQDTARRCVHQAKLLEYCRSLGRDGVALFFKRIETRDHKAHDLFYGDVQDTYVKIMTRVKEIKAQQAAGTSSEGIEQIQLHAVEPGTVINIRVPPADSADPEVAKARQIFDNFAPDMRKALESGSLDKVNEVLGRMKVDEAEALVGDFGEAGILSLEDEIIDATTEEGRAQLKDMGREDFVDEKGVETDAPPAAAPEKEEYGDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHB3</accession>
    <name>A0ABR3ZHB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MDV1</name>
        <name evidence="10" type="ORF">Sste5346_002408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140680">
        <property type="term" value="F:histone H3K36me/H3K36me2 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd22881">
        <property type="entry name" value="Mdv1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="342"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="384"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="479"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="594"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="426"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="210"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="714" mass="77370" checksum="E474C51F750D1C73" modified="2025-10-08" version="1">MANDDSHNAYHDDLGGDEDTSIISAAGIEAFGRKVTTTASHLMGPASDNPSANAHYQSAMSEVHRQLRRPHVQRSVLAMARTTPTDMVRSRLSTSEIRHRALSYLPEEMLQNIPEDDNAYSLFQGFQATFPEMTEEGKKHGHHGHTGNANHRRRSSRGRKMLDDKPSTPDGPHALHKMRKEKSAMMHQFEMLGIRKNMAGSEIREIDIKVANLAGMRKILLDRLANLEQDEALLEHDIMDLEGRIDIAQELADEAESIAANSPTKSDVDLALDNDDEEGALESTNGDASTGFMSQSIYEKIPSAGSTPSRSTAGRRTPKVLRKKSMPILHEHFHPGTSIREIRAHQDAVTAIDFDAPFGTLVSAGMDDTVRVWDLNAGRCIGLLEGHTASVRTLQVEDNILATGSADATIRLWDLSRSRYDPHGSLFSKSGNGGASGGSGGGSAAVEDDDDGGIAFENPDDEPVEPPADSMADCPLITLSAHMGEITALHFRGDVLVSGSSDKTMRQWDLEKGRCVQTLDVMWAAAQASASVNSAASGTGVGEGGTWRQTSRAQTEAADFVGALQVFDAALACGTADGMVRLWDLRSGQVHRSLVGHTGPVTCLQFDDVHLVTGSMDRSIRIWDLRTGSIYDAYAYDSPVTSMMFDARRIVSAAGEDVVKVYDKVEGRQWDCGAGIAAAEDGHSTAPAIVEHVRIRDGYMVEGRRDGRIGVWTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHR3</accession>
    <name>A0ABR3ZHR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032157">
        <property type="entry name" value="PAC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16093">
        <property type="entry name" value="PAC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="15709" checksum="0FC5E2BF3EB92D8F" modified="2025-10-08" version="1">MATDRDSTSKTVTFSTPLPHALDTQIHVRLTTRDKCLMLFVTTAGTDEGEALAPMGSFVYAVPDRFKPSEPLCTNIYVEENSLEFAARLARLVVKRTQQPVYVSSSLSLDRMGLGGTVEEVLEAFQAVTAPLLPLLPKPLQNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHS6</accession>
    <name>A0ABR3ZHS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">HRD1</name>
        <name evidence="19" type="ORF">Sste5346_002537</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 21">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16479">
        <property type="entry name" value="RING-H2_synoviolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057992">
        <property type="entry name" value="TPR_SYVN1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058051">
        <property type="entry name" value="Znf_RING_synoviolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF184">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25563">
        <property type="entry name" value="TPR_SYVN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="363"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="446"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="654"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="690"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="777"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="842"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="446"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="473"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="777"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="842"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="873"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="896"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="908"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="923"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1900226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="944" mass="100371" checksum="1C13EE167ED1B87F" modified="2025-10-08" version="1">MRLAWYAGASTVLAGGVVLSAFHQRANFYSAMVYLFQSNLCMMILVNLIALVYSSFVYSLQRVCFGQLRAIEVEQLYEKAWFAVTETCLAMTIFRDEIGGFFIVMFVTLLTGKVWGWIGEGRIEALEQQPPANPRLFHTRLIISLFLSLVYDAWLLYYAVTTVIDQAKPDMMVMFLFEFAVLLVTSLHTALRYSIILLDTSIIKRQTQERLAERRREIREERAAIIRRREEAAAAAEAAAATGQEGGEDAVATVDAEEDNEPLPDEDDVDEMDIEVAGWEAKGQYILGLDLWTDFTKLCIYAVFFFVLLNFYGLPLHIIRDLFMTIRSFIKRLGALMKYRQAIKDMNRYEDASEEDLARENTCIICREDMHVWNQNDPSRIERTRPKKLPCGHILHLGCLKSWMERQQVCPTCRRSVVIDDASNANRNRDNAIFRMNLMGGGAAGAGAGGAGGAGGAAGAGGAAVAGAGAGAGAPAVPAADGAIPPPNPAFPAINGQAPAPGAAPGAPADANQHHPPPPPPPNGGGGAALRMFNFGPLRLGFAQGGARDIQEMAQRLGLPNAMAGGNNHAVDQGAPNGVAGAPGFGAPDFGTPFGYHPLPAGPASTMSQSTSTAAIFQDLRSIERRIEQGTIELQLASAEARTLRTMLSELQRIRTTQHVRPTAPQPTPTVPLDANAPEVAEAPAVPEVPAAPAAPEAAAAEPAAEPAPEATANPTEESPTGATQAPQEDAAAAWPPASPIMFMGPAAVGFDGHEQALAGLEERNRQRLEQARLSQRLTAQQPLPSVNLEVSGSGSTNRSSQLPPGVQLPPGWSLVALDQYDGSSPTAANVNADADVIADADANANNHSSSSRSVLSHVAAGREGAARPPSPLLSGLFGPPDSLTAATIAATPTPALAPMPATPAPAPTRTQQPARQVQQQNNEEESSSEDSNDSSEGESSDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK67</accession>
    <name>A0ABR3ZK67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF103">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="56766" checksum="00F00BC1E12A0015" modified="2025-10-08" version="1">MSHEDKKDIMTNTDADATKAPSVAAGAVTEAILHNVEKDFEDATAVPVLTLEENNKLLKRIDLYLVPVMLFSYLFQTLDKSALSYSSIMGLETDLHLTGLTYSWASSIYYLGYLVFSYPASYLIVRLPVGKLIGGACVAWGSVLLCTTGTTNAAGLLVARFFLGVTEAAIAPGLTVLVSMWYTRSEQPLRHGVWFMGNVIAGFFASLLAYGISFVKSPVLQPWQVLFLLFGGVTVVWGLGLLYLLPDHPATARFLTPQQRQQAVVRVAANMTSIKDEHFKLYQLLEGLKDIKLWLLFWIMVAMSLANGLASFQSIIIQGFGFSTVHTYLVQMISTAFQALFVLIATIGSTYIPNSRTYFMIFNYTVSVAGAAIVYKLEAERVWARFFGYCLCIAFSANYPLLFAMGTANIAGFTKKTTANAALFVGYCAANVASPQLFLAREKPTYPSGFKACIACISMSVALTAILRAYLVWENKRRDRVYGAVTNENTEEVDVALGLSDQTDFELKQFRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK91</accession>
    <name>A0ABR3ZK91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-dehydropantoate 2-reductase (Ketopantoate reductase) (KPA reductase) (KPR)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PAN5</name>
        <name evidence="6" type="ORF">Sste5346_002367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="4">
        <location>
            <begin position="18"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="5">
        <location>
            <begin position="239"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="408" mass="44673" checksum="EBEA3F723512992C" modified="2025-10-08" version="1">MCRAAANRLSEDDERRRIYVLGMGNLGRLFAVSLAKLPNRPPITLVVHRPGLLEQWRSNPGVVLHPPSYLEGQKDTDDDSSRITDFDIEMWSEAPPPSGQESTEISNISNLVISTKAQDALKTADWLRRYLGPESTVAFAQNGMNKLWPPYGAIYNDARHPSTSAERASPQWLACIVTHGVFSIGPFASVHASLADVVLGVVGDDDLAAPGQDSYLVQQIMAASQLNARWAPRHELWVLQLEKLVVNCIINPLTAILRCKNGALFVPGGESAVPEIIDELLEEASSVLRTLVLHEIENGTIFGQDGNSGTDKDALVERLSFKSLRAMVYRVGELVKDNNSSMFQDASAGKKTEVGEMNGWVVEMARYLESVGATDGGKPISVKTNEKMVDLVEKAVPLSKDELNSHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK2</accession>
    <name>A0ABR3ZKK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Xanthine dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_001985</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="13">
        <location>
            <begin position="25"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="14">
        <location>
            <begin position="258"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1403" mass="153570" checksum="AFFA94ED8F147BC5" modified="2025-10-08" version="1">MAPGAISPERGPYDAVGSLTTTFDDTLRFYLNGTRVVLDEIDPELTLLEYLRGIGLTGTKLGCGEGGCGACTVVVSQYNPTTKSIYHASVNACLAPLASVDGKHVITIEGIGNVKSPHPAQERVARGNGSQCGFCTPGIVMSLYALLRNNDRPTEHDIEEAFDGNLCRCTGYRSILDSAQTFSINATSGCIKTKSNGGSGCCMDGKENGGGCCKDNKESNGDQPIKRFTPPGFIEYNPDTELIFPPALKKHKFQPLAFGNKRKRWYRPVTLDQLLEIKSVYPQAKIIGGSSETQIEIKFKAFNYPVSVFVGDIAELRQYAFSDDYLTIGGNVTLTDLEHLAGQSATQYGPARGQVFAAINKQLKYFAGRQIRNVGTPAGNLVTASPISDLNPVLVAAEAVIVAKAKDTSDPTGVAVADIEIPMSGFFQGYRRTALPNEAVLAAIRIPITPAKHEYFRAYKQAKRKDDDIAIVTTAMRIRLDANGVIEQCNLVYGGMAPTTVSAKTANAFLVGRKFAELETVEGGMNALEKDFNLPFSVPGGMASYRKALALSLFYRFYNEVMTELNGEGAVDGVDGMDGVDGIHSKNHFDRQAVEELERVISTGETDNDAAVDYAQEIVGKANPHLAALKQTTGEAQYTDDMPPMKNELHGCLVLSKKAHARILSIDYETALDLPGVVEIIDRKHMPNDAANHWGAPNFDEVFLAEDEVHTVGQPIAMVLATSPARAAEGARLVKIEYEELPAIFTMEEAIEKESFFNFHRELKRGEEVDSAFERCDHVFTGTARMGGQEHFYLETNAAVAIPKLEDGEIEIFSSTQNPNEAQAFAARVCGVQANKVVVRVKRLGGGFGGKETRSIQLASIVALAAQTMRRPVRCMLTREEDMVTSGQRHPFLGKWKVGVNRDGKLQALDLRIYNNAGWTWDLSAAVCERAITHSDNCYNIPNVRIRGRLCKTNTMSNTAFRGFGGPQGLFIAESYMSEVADRLGMPVEQLRAINMYKDGELTPFNQSITDWHVPLMYEQLQKDVDYNNKRAAVTKFNEENKWRKRGLALIPTKFGISFTALWLNQAGALVHIYHDGSVLVAHGGTEMGQGLHTKMVMIAAQALKVPLDSVFISETATNTVANASATAASASSDLNGYAVYNACEQLNNRLAPYREKLGEGASMKDLAHAAYFDRVNLSAQGFYKTPEIGYSWDENKGKMFFYFTQGVAAAEVELDTLTGTWTCLKADVLMDVGRTINPAIDYGQIQGAFVQGMGLFTMEESLWLRNGPMAGHMFTRGPGAYKIPGFRDVPQVFNVQLLKGVEWKELRTIQRSRGVGEPPLFMGSAVFFAIRDALKASRAQYGVVAKTVDDEAGKEDLDNDQGLLSLESPATPERIRLACVDPIMERARVKAKPGEESFFIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL32</accession>
    <name>A0ABR3ZL32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="207" mass="21425" checksum="FDFB3FEC8E173BCD" modified="2025-10-08" version="1">MAVLQIVAYDVGFAALAADGGVWTWGDPRFPECLGRGIDDTPAEHPGRVASLDDLPTGPIVKLAAGGHVLAAVTQGRDLYCWGGYPGRRPVLEGVTGEPTPIIISTVSPNGDDEEADIVNVGIGDGHMIVLAADGSVFVIGSNANGQLGLGFESVVDEDDDEGSQTSEAKTPSAWVKVAWVKVNGLLPDQVTGVYAGPRSSFVVVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL36</accession>
    <name>A0ABR3ZL36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">C2 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_001948</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="251"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="476"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="665"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="701"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="870"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1095"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="709"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="878"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1138"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1170"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1216"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1235"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1249"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1332" mass="147149" checksum="D6CE6CB9037E5499" modified="2025-10-08" version="1">MSNTQERIVPSGQHYSGNNRIPNIKQFMDSLDNEKKQRDAQIDAQQSQQQQKQHRLASANKQGGEVADHTENEVSGKRRRVVTDPVTGHEVEIDDMDGKLLKAVRDPILSVPNANLDKETTAKTEATQSGEEYRRNQDITAPPDPVEPGSTSDVPIHGEKTNVLFHPTPSVSYEPMYIALEARANVLCATIFLAIILVGRLFGGRLVGLIPLAICVASGIFLWFKDLIRQGRDIEWSSEQKRGETAVVNLIPESVEWLNSALALVWGLINPDMFAGVADTLEDIMQASVPGVVDNVKVNDISQGSNPIRVLSLRALPDSHVKDLKEEIRKDNQQNKDPQEAAADEEGGEFYNLEATIAYHSLPSGNDVASKAKNMGMQLVFYLGIRGLFGVPFPIWVELNGLVCTVRLRVAFTPEPPYVKTLSFTLMGLPKIDASCIPLMEKGANVLNLPLISNFVNWTIATAANMYVAPKSMTLDIGKMLQGDGIQKDTTALGILFIRIHKATGLSKQDARGSKGGGSDPYICVAFSKFGKPQYCTRVIQDDLNPVFEECAALLVTPDIIRVDEQLSLELWDSDRSSADDVVGKVELSIQKLIRHPGKFFPQVSSLRGVKAESTMPGELHWEVGYFSKTQFRRALRTDGKNPALPKELREDPKFQDDHGVITSAEEDAVVHTPPDPLWPSGILSVVVHQVVGLELENVKGSNGKRKGREYEPARPEAGELKEEQGKKLPSSYCTIIINDELVYKTRTKVVSSKPIFEAGTERFIRDWRSAIATVTVRDSRNRQHDPIIGVVPLKLSDALLTGSQSTRWYPLDGGIGFGRIRISLLFRSVELTLPRTQIGFGEVGTFEFLSDFITSTKWAPSSRVKMRLRTGGSSHNIRSDKSSRTDDGNGVRWDISGADEEAKDHKAKHDNRVRLPVQYRYRSPVFFELHPVGRRGKDAYACVWLQDIADNEETTFDIPIWKCDNPLRLSQNYITEENNKDIPDIEIEELGRLQFRGRFKPGMDREHLKFVSDNDSRETVETWEACFAEGVRTEVVEAQVPKHVQKLHNESLIKSRDVLANKSKGDQQKWLAKDGTDWSGAFGTSDSAQIDAANAAEGQGQGPTAEESAAANIAGGDVDGVGGGPSRRETMNSIGAYDDDDDDDEFDYEDDDYDEYDDDDDIDENGETSSRGAADAASRVSRRRSMRSARSSGHRSQPSGDSVDLGINDATSVKSGAGHSRTGSGATGGAMSSKISDGNGSVNGGQNSTSTDGTSISGSRRKSISSITNPIKQYKEYKTRNRDLHRRHRGLMQWKPMRNMQFAKDEATFAVRRVLNVGKLNGRSPDIETEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL46</accession>
    <name>A0ABR3ZL46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl15</name>
        <name evidence="6" type="ORF">Sste5346_001825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="203" mass="24210" checksum="3A029E801CBF1F5C" modified="2025-10-08" version="1">MGALKYVEELQKRKQSDVLRFLLRVRCWEYRQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKKPVRKGATYGKPTNQGVNQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYFEVILVDPQHAAIRRDPRINWIVNPVHKHRESRGLTATGKKSRGLNKGHKFNKTRAGRRKTWKRHNTLSLWRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLN9</accession>
    <name>A0ABR3ZLN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="374" mass="41658" checksum="683BAC4FAA934C30" modified="2025-10-08" version="1">MVKKTTMKKAQVVRPRLSRPVAVSPAPTPVFSSLTTPSSSALPSALPSAYVSEDEDEVAQPAKFDISTIPIHKLSIVETPGEPAAGPTATTGPDGTPVDTADDKGKEPEKPIQPFRFLDLPSELRVKIYGYHYEGVDPVADLTPDNYKKIFRKLFLLRTCRTIYHEASHYYFSRFTFRIFPTYPGRFFKTRRPLLARLKKEQRNAMTSLELRLGPGFNKPPKCWVVNRKLGLKDCINVRKLNVFVQLDPSVSWLDGFRKAGFYETFSRDLLNDILQETPNVEVVEFDAYESVRKNCPIMEALQQTVREHGKRITWGPKNGWTATSDNAANTKLQQGGGGAGNLIINVGANANNGGSNTAIITYDTYDNPILSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMA7</accession>
    <name>A0ABR3ZMA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MGS207 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF6">
        <property type="entry name" value="MGS207 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="53123" checksum="5846E63B5D098667" modified="2025-10-08" version="1">MALLSSIPLVGRIVDAITGASSIPAARRLPSSPIHAVETSPEKRPRTLKHLLRGNHVNHALLYGDDNGRHNHMAHALCSAYLLGATPEQLNLIYDAIAPKLKAWQTSPAEIADVDWRDYLGDTDYQRAYVDFFEDVLAEHSVAYNWRTVVETYLLGQGRPRGDDDTVEVEGDQVDTIFSSRATPHGEGEGDKGTTEVDKYVLFNSLICGLGHPLIHLAYAYEMDSRVLAMEALGMTAVTYNPEYAKRYTFGKLPMADDVSDSLRGLSLQQLVDRIAKDKRFDVIPKGSRVESVMLEPPSAEVETALLEYWHAWDLSTGGDDKFDKNDLTPRVREAQDVSVQMLVASVKPGTHAYNFFVCHALTSSHAMRVLLPEIPPALHVGLLQQWWLLTLATYVAVGRPIVDQDNIPPDYRKTKGWTYVEQQAVSSRWSTDEHYIKTLRAIKDAARTWGDIQDRYLNAAVWFSDDFEDWVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMB8</accession>
    <name>A0ABR3ZMB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1,6-mannosyltransferase mnn11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MNN11</name>
        <name evidence="5" type="ORF">Sste5346_001807</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF10">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="376" mass="42190" checksum="64F382AFAFE0FB68" modified="2025-10-08" version="1">MHFAYPPRKNSNAASFKPRAPTSRLPFIRRGRKRVIALGALFFFGIIYFLTRPGGRHSGANPWMSAHLKAAQQEGTGSTMPGVGGNKAPLASDGNPYGADFSAATENFASFGKTPNVVLVTVYDETNFHRAYLDTVRENRRQYAKKHGYGTFSPKVGYYDLNGSPLSWTKVVAMRHALTLFPESTYFWFLDQNAFVMNMDMSIEGDIMSPAKIDAAMLKDFPVVPPDSIIKTFGHLKGQDVDFLLTQDYDGLSTSSFIIRNGEWARFFFETWFDPLYRSYNFQKAETHALEHIVQWHPTILSKMALVPQRTINAYSKVDHGAKYESGDLSVRVIGCVRTSSAICENEAAPFIEIWRGGDKQHQQQQQAQQAQQAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMC8</accession>
    <name>A0ABR3ZMC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039510">
        <property type="entry name" value="Vint_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032838">
        <property type="entry name" value="Vwaint_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF156">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14623">
        <property type="entry name" value="Vint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14624">
        <property type="entry name" value="Vwaint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="89"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="806" mass="87385" checksum="80F6034FD7AFF3A6" modified="2025-10-08" version="1">MVRVPFLSSSKEEAPKKEEDAYVQSNLSLRPKPSDLPVAVAIHRLPTEDGIIVKVTPPKQPADYPSEEAASASNDAEEAAAPPHHVPCDIVLVIDVSGSMAEDAPVPTVEGERPERNGLSVLDLVKHASRTILETLNEGDRLGIVTFATQVNVLQELTPMTPANKKKANAKIESMVPEDATNLWQGIVSGIGLFNGGKTKSGRVPAIMVLTDGMPNFMSPPQGYIPKMRGIGRIPAPIHTFGFGYSLRSGLLKSISEFTGGNYAFIPDAGMIVSTAAVYCFSSHSSLTFQGTVFVHAVANMQSTFANNAVLRLTYPQSLTIEQTQGATVGLHQPVDRVQKQELVVDIGNIQYGQSRDVYLRYKVGPDVGTQAIVNVELEYRQMSTELYRTSTFSNLADAKLLQKEKGDSDDMAVDNPPLPAGEAAFHISRSMLCAFLSSIFPMDATDEHLNPPFTVSVGGAQLDSLIESLPAASHEHSSNPACAALMTDINGQVRMALAKADYYNRWGKHYLPSLQCAHAAQQCNSFKDPGPLLYAASSPLFIACRNALDTAFDTIPPPKPSKKAPSPYFGTHSAAPNMQPRGRYHTGPLRNILGSHSNSGEAPPSYSSVTVDMSRYHNSRGPCFASFCRVTLADGRHIRVNKLRGGMRVQTPRGPRAVAAVMKTPVSSIPMVTIGRLLITAWHPVSHNGSKWVFPCRDPAANKKTAVRYTGSIYSVLLQPDEDADSHAINIEGVWVVTLGHGLTQKEVDEDGDVISHANDVRVHRFFGDYSAVCRSMATLDVRKDGLVVNGGSSRSNFRLWHTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMG2</accession>
    <name>A0ABR3ZMG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001588</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF3">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="4">
        <location>
            <begin position="5"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="5">
        <location>
            <begin position="180"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="33505" checksum="28757B8F30DF7488" modified="2025-10-08" version="1">MAPSVFFVGLGNMGYAMCKNIVQKANLDKPLVVYNRSKERSAALVEELAAPGKITVADNVAAGAAEADIIWLMLSADAVVESVFDEVLSSDANLEGKLFIQSATIHPDATERLAAKVEKRGALFLAAPVFGAPAMAQAGALVGVLSGSAAAVERAQFLFKGVTSRHDILLKDVPVSHAALLKVIGNTFVFNMIEQLAEGHVLAEKTGLGTDPLHQLMQAMFPGPYAAYSERMVSGQYYTLERPLFAVDLARKDIGYALGLGDKVGVQLQNARTADAHLVQVKEHDGETGDVAAIYGAVRQESGLPYENQKEHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMK1</accession>
    <name>A0ABR3ZMK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF5">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="181"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="281" mass="28702" checksum="5FCB4945BB6A6A7A" modified="2025-10-08" version="1">MPRRTKLVVIAALAFTIAMMLYTSSLRDSRSSDQRTIQDFYHKTKGALAPGSAGSGSDSGPNSNTAPKIVDMDNDGDIDEEDVRLAREMQSRLKAAEQQAKDNANAKAPNPPDAPSNVIGVGSSANGQKGAAGGAGGAAAPAAAGGAVAGAPAGAPADAGAADADAAVAAELSTILKRAPVVIFSKTYCPFSKRAKGVLLDKYVIDPAPFVVELDTHPLGPQLQARLAELTGRRTVPNILVGGTSIGGGDDIAAMDTNKQLVEKVSTLGSKWGVVMKERLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN19</accession>
    <name>A0ABR3ZN19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="18"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="641" mass="69102" checksum="40006A2A06268845" modified="2025-10-08" version="1">MTAPPQTSTSTSTSYKNKTLIVCCDGTWVNATGKKSRNAPPTNVSRLIRVLQPTNSHGEPQIVLYHAGVGSSGELMDAGMGGAFGFGLDQDIRDLYQFLCLNYHGGDRVVLVGFSRGAFTARSVADLVASVGLLTAAGLDRFYDIFDDYENMADPKRTPSQFICPAGTLEAFAGQKGEAWIQWENRRKTQYRGWLKQNGYTVDSYLRPEGGETEIRILAVAVWDTVGCLGIPAVPVLGLQGSARQWKFTNTQISAKVEHAFQALALDEPRYAFLPSLWERLPGNNVTSLKQVWFPGAHSNTGGGYRDQQLANLTLAWMCDELAAPGVGLAIDEQMLAEVFMDGLRYSAVHPYPQVPAIDILSNGLSGVAGSLVTGLFKKGVDASHKGGVLPWAKSGVMGDAAASKAKNAVRDSVDCPSKYLHFHPDASVSDLWSQGARSWALGQARMPTSFVQRAAGMTVRKPGQFVRVDPESNDAQPDQPLVNTNEHVHASVRVRLACGGLGMDDKYVWTCEGLTGRKPVKDDGGSDVSSDDGHDASPLWTLQRVDGVADVGGVIVTSDDSGYPLSKVAGAGQWQWTYTGRPTKPTKADRHSNNQMSTPPLVKVLPEALPTGRYERMLLGMAVGKPDVLAWAAANPYKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN65</accession>
    <name>A0ABR3ZN65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NDH51</name>
        <name evidence="15" type="ORF">Sste5346_001619</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 12" id="KW-0288">FMN</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="14">
        <location>
            <begin position="407"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="524" mass="57223" checksum="CAE52B9EE2FA5D80" modified="2025-10-08" version="1">MLSRSASAAPKAASAASAVARVAPAISSTTSISSSTSAPSSLPARRNFSSSSRRSMATVQDATPEQPKKRVYGGLKDQDRIFQNLYGRYPPDLKHAKKMGDWHKTKEIILKGHDWIINEVKASGLRGRGGAGFPSGLKWSFMNFKDWDKDNKPRYLVVNADEGEPGTCKDREIMRKDPHKLVEGCLISGRAMNATAAYIYIRGEFIYEAEVLQKAINEAYADGLIGKNACGSGYDFDVYIHRGAGAYVCGEETSLIESLEGKPGKPRLKPPFPAAVGLFGCPSTVTNVETVAVAPTICRRGGSWFASFGRERNQGTKLFCISGHVNNPCTVEEEMSISMRELIDKHCGGVRGGWDNLLAVIPGGSSTPILPKHMCDDQIMDFDALKDSQSGLGTAAVIVMDKSTDVVRAISRLSHFYRHESCGQCTPCREGSKWTEQIMTRFEKGQGREREIDMLQELTKQVEGHTICALGEAFAWPIQGLIRHFRPELEARMQKFAAENGGSALAGGWTHDARQQGKLIAPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND7</accession>
    <name>A0ABR3ZND7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001661</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF7">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="79"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="567" mass="61383" checksum="889C77852487874D" modified="2025-10-08" version="1">MGSVAPSWQDKAAAKRQAVLDLIPVAWRLPQPLPTYKAQKDVTGAYVQQHLSPREIEITEADVAQIVANTTAGKWTATEVVTAFCHRAAIAHQLTNCLHEIFFSQAIAEAKLLDAKFAASGGVPSGPLHGLPVSFKDQFHVRGVETTMGYVGWIGTFEGKKGTGKEKVVESELVREIRGLGGIPFCKTSLPHTVMSGETWNHIVGFTRNPNNRLMSSGGSSGGEGSLVSMKGSPIGFGTDIGGSVRIPAAFCGLYGIRPSFGRLPYAGAANSMPGQNSIPSVCGPLAGSAASLKLMLKAVLTQEPWLYDPAVVELPWRDSLAASLPASAAELGEVLTFGLWESDETVAPTPPVKRAFAMVKALIEKLGHQTIEWQPPSHARASELAVVAYTADGGADVHHHLGLSGEPLQWRIEEFYGTQPFQPKTADKLYDYNLELFQYRQDYMNYWNSTAKLTKSGRPVDAILAPVAPIAAIELDKHTHIAGYTPWVNTLDYTAAVFPVTKVDPAIDLVEEDYTPLNDVDKAIHEEYNPQIQENTPVGLQLVGRRLQEEKILSLVEMLSAALAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ0</accession>
    <name>A0ABR3ZPJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="413"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="58323" checksum="DCA44C4C52B13BF0" modified="2025-10-08" version="1">MIGRGSYGAVHIATDQYGKEYAVKEFSKARLRKRARSNLMKQGPFRAGRFPGPGGPLGPPGPSSRFAGEAQAEAKDALYLIREEIAIMKKLNHPNLVELIEVLGDPEQDSLYMVLEMCKKGVIMDVGLGKTATPYNAEACRCWFRDLMLGIEYLHEQNIIHRDIKPDNLLITDDDVLKIGDFGVSEIFEKSDGMRTSKTAGSPAFFPPELCVSNHGDVAGPPCDIWSMGVTLYCLRYGRIPFEHDTMVEIYEAINTAEVNLPDDEDPAFVDLMGKILEKDPAKRITMAELREHPWVTLKGEDPLLSKEENCANPIEPPNALELNHAFTQKMGHLLCVLKAIRKFKGLLHSRRDPSLNVPSFASDVADLGSQMSSIRVASDQGLTSEDEVARLVEERRNNIRKISLQTGMLLGSTATEGQGEGSTSAISDNAGGRESGTGIGADQPTLLLGIGTGGADDFGPGGQHAEPEDIVSESPTTAEFDVYDRAFQSEVARIQSQSNNFKVYPNKVLESKAGAGGGGGNSMADVVARLIKEGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ19</accession>
    <name>A0ABR3ZQ19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PMT4</name>
        <name evidence="17" type="ORF">Sste5346_000704</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23285">
        <property type="entry name" value="beta-trefoil_MIR_PMT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="598"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="636"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="725"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="332"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="463"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1902793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="775" mass="88200" checksum="D1A3A11729936AFA" modified="2025-10-08" version="1">MAASSTPQGTLRQRNVAGSSKKKDGAASDSDLDTIIKEKTVSAKKDAQRDYQITGVIITALAFLTRFWGISHPDEVVFDEVHFGKFASYYIQRTYFFDVHPPFGKLLFAFVGWLVGYDGHFHFDNIGDSYIANKVPYLAFRALPALLGSLTVTVVYLIMWESGYSLPACVLAAGLVLLDNAHIGQTRLILLDATLVFAMACSILCYIRFYKLRHEPFSRKWWKWLIFTGFALSCDMSTKYIGLFAFVSVGSAVCIDLWDLLDIKRPGGALSLPDFARHFAARAFGLIVMPFLFYLFWFQVHFAVLNRSGPGDDFMSPEFQETLSDNVMLANAVTINYYDTLSIMHKETKAYLHSHADKYPLRYDDGRVSSQGQQVTGYPYNDTNNHWQILPADGDENTNRAVQNHDLVRLRHLVTDSILLSHDVASPFYPTNQEFTTASLEDAYGDRAADTLFEVRIENGKPGQEFKSVSSHFKFIHNPSKVAMWTHTTPLPEWGHKQQEINGNKQITPSSNIWLVEDIPSLPADDVRRAKVERSIKTLPFLQKWFELQRSMFWHNNQLTSSHPYSSLPYQWPFLLRGVSFWTQNDTRQQIYFLGNPIGWWIASSLLAVFAGILAADQFSLRRGMDALDHRTRSRLYNSTGFFFLVWATHYFPFYVMGRQLFLHHYLPAHLASTLVAGALIEFIFTTDASEPEQPTYQQVKSGKKAAPGPKRHILAGERFRGQSLMGAWIACFVILAVVAASWYFFLPLTYGYPGLTVDQVLKRKWLGYDLHFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ78</accession>
    <name>A0ABR3ZQ78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="66681" checksum="F9124C7D59B9F673" modified="2025-10-08" version="1">MSASGRVRLPDAPAPGMFQVISLGDNGSSNNNNNSNQIREYKRRRPHKKTRSGCLGCKQRRVKRECVYEGAEGAAASASTSRSKGQKAEDGQEEASSSAAKVNRLSAIRSEARRVPQSQDGGNHYAMGSAHTGHDRHQPSGNAHSLVPTSTTTPLVPSPRLVRVQPFQVTGQELGTPSNELLYHFEVTGSALFGMPNFMGPILPLALQFPHLRGTILASAAAHLTHRAPGFKSYHLAKHYQQGVALQNYQTALSTSFVVQGQLGVDVLLMTAMLINMLMFVMPLDENEARNVWDGSSPGPAPPCADPDPDPRRSWVFSPHPDRLSWLAIQMGLTPLLIATAPWREKSRLRLLFANSDDEQRTLSGTWQSLRRVPQPWLDLFGFNRDATPRPNYRGSGVTTPAPATPTPTASHTPSQYGEDTDMDPDSKSHTMKTPRSGRSTPGAGGSGPASPASTTSTNTTATTASTNLSGIEDTVSEADRIYRAPLRVVAELLNTPVNDRTLLLYFQFVGQLDPGFRHKLFERNEKALWLFGMWMGLLCRFDNVWWTRRRTRCDFRAIRLWLHLVGVAQRPGAEGELWRQLLQDLDDTWGYHFESDPIMRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ93</accession>
    <name>A0ABR3ZQ93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="224" mass="24144" checksum="60A8861FF4E0D6D0" modified="2025-10-08" version="1">MTNAQIYSAFKSYVSRLHDVLNVRRNKNTKPRLVISAPFDFKKEDSMCILPGISSEELYMLREKAAASIVGSALTNPYETYSDSATLAPSVHDLHLGPGSLNRSTSSFDKTSLHRHHLSHNHLAKSMTAPLAMSPGTMLVAPPTPTSIRSATSSSTSPTHHHGNINHHHTCCRRCKSAAAKEQRIGGGVSFYPPIVLASTEPYAPTGLSFPSSSSSASSISSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQM8</accession>
    <name>A0ABR3ZQM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ino eighty subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038014">
        <property type="entry name" value="Ies1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287:SF1">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="764"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="891"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="942" mass="102362" checksum="DF1390F79E4F658D" modified="2025-10-08" version="1">MASPSSAVSTTEVEPRTSPARDERSFANNNLTEDEASDRDDGTPRNVSRNTSRMVGTPDVQERRGGAGGGRGGRGRGGRDSSAAGGPGGPGMFKDPSAIGKIRHLKKEDGEPLWRFDIQYDFLRAIFDDDHRVFTNSYEPDTMPKQCFADLYIDTMARSSKTSKILHDKLLTDREAAKNMAMVCLLVNIGRMNTTLNFFPEMRAQLRTYHAIPSLQANEKLLDYKQLQDAPRLKSILKGGTEDRAEPRSLDILKETDVPRTNPVNLLFLICNNASKVAELHFPPGREFHDLIMKTNLTSESRARAFLWIVWFYLESDFTEEGCEENPFGAGVDYGIDVANQGVPVMVEMTPEEEAQENIDTPVERAFGLSKKSLRAKILHDEQFVEMPPHKRSSRPSRPSAAATAAAAAKEAAAVKEAAAELAGGGGTDNERSVPPAILPRIRPSKHESDLESMRSTPPPRSLIRSFGGGGGAGGATGSARRGGPHKFSLGDGGGPSPVRQPPLIQQLHQQQQMQQTRRKRKQVKPEGGRGSRHRREEDDDDEDDDRANTSVAPSRKPRPPTAHQIAVENNRKQRIEYLLSRGMHRKHHRSRKTRRTEGAIVRALRRLEEVEDPFENSEDESNLSFNRDLFTFMLGAPQSMATGNEFRERGFHGLVQLKSEPEDFGEEVSTYASAMRRACRRLNRWETDGMPKNMVVPTIKRPRVNVPPVEDEYRDPNETEDEQDADTQGMDADASISMSFVETTPAAKKRRTVGATGQVPAVAALSRGGRGGRTSTGRIPSNTPAAISARRRRAAKAAAALAAANGDVTMSDAGTRHGSAAPGAGDDGAGDEDATALASGAEGEGDAEGGEGGDDAGDDTEDVASVSATPPVNKTRVTIKKKTPGPSGLSASTSSRPRASGGRSSKVKREDDDDDETVNNDDDDELNDVDKALLGMGSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQQ7</accession>
    <name>A0ABR3ZQQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA topoisomerase 2-associated protein pat1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PAT1</name>
        <name evidence="9" type="ORF">Sste5346_001458</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="1"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="192"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="540"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="540"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="888" mass="97943" checksum="4347A5FA37C5C78E" modified="2025-10-08" version="1">MAFFGFDQSSQSRHNTCAPGFSQTNDPFAGLASGSAVDDALEFEDTYDGLGDQLEETGDAFNDDTFGGDDGLGSGSGGLGGGGNAGGFGSAKVGNDFDFFGQTAKVSNAIDEEHARFNRLQPINRNPIPPARDNYGHHQQHQGPSVGSYNSNYFAPAPAVKPVRSGYEKYKEPEADMQVDAALWGVAPKKPATFSTPQASSTPSQVPAASSSRKILSLEEVEAQMRNQSKPQQQAPPVQQPQQSMYQNEQFHQQPPPGDYYPIPPQELMGDPSQLHNMNHPMALLQRPPAQQTPPGMFPHPQQLQHQHAPPVQPTQILQNPNRHPEQFGVPPPPFPNQPSHHRQTSSFSGAPHIITHPSQLVHLSDEEKAAYLEQEAKRAKRNHKIFLLSKNNGLMTPQDKNFVTRIQLQQLVSATGNPNEHGTDEALREDFYYQVLNQIRGGNRQHPGQPLNNFAQTYLFQTGSRFNSRRYMNRDRGADNHMQRMEQQVQRAVEAAKNRPKNKQLVIEGTLGKISFSNAKTPKPLLNIKRSSEAAAAAAGGAATGTEGSASGSGSDRPASAHHKVSQSTSAAAAGGHKRVLDRKTVLNSIEKVYATLMEIEDHIRLIPPPPTEQDDLELIQRRGEWEEQMEQLKTQLWRELKVHEPIGEFPVHPFIAFLSFPKGKKAIPRVFRHLSDELRATVLTMIVVHLDQLDIVRNAQVTSDNAQGTGPNAALREEIELFTLTVVHTLFNFMSELQLDMVTGVLGLITNLKVDVIARSRIGASMLTTILSRAELIKQAAGGTREQWQSWEITYNNFFNALEPVLPYMFPGTVSSGEDMYVWQLLAALGIGATADQQQRLVLAVKERVMDTVAVAKTLPVDLSAQRLQNVNLFMRSIGLDVELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR66</accession>
    <name>A0ABR3ZR66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="911"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1134"/>
            <end position="1162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1310" mass="142456" checksum="61A0C0B43621A363" modified="2025-10-08" version="1">MPSRNSFSIRKLFSSPRRLSLIADEAALPTDERFLHSNNSTKRRSDASTNSALSDESRGSSRGSTASDGTRTRSRHGSRGSSGSSSTTIFHPDSSISITTPQAERGLTDNVDHELSQEEIDRIKAVVAAAAAAAASSLRLRMDNEGSEAARTVRTIKTIQATTFDRILMSHETNASTSTTNTTNKKRSESTESAIIALAPPNLLSKALPPPPPPRVSSYFATRPSWKSKTEKSEKFEKSIKTITAPSKTTDTSIHPLYRDQNGEPDCKKDSGIALDQSQTSLVDNTEKETKKKVVTIAHIIDSDSDSDAGSCIDLLQALAIQPEEAGLLRRPTADSTSSVSNMMQPSSLLTVDSDSTANANLNTADGPGLRNVCTTPTFTQPRMAPTPSPSAVPSAVPSETNTPQRMMSPSPSLSPRPSFMGPTSRASGTFSAMPVSVSPSPSSPKKQGTRFLPLRLNKGLPDAALRIQRKRSKKARKRERQAASNMKGESFSDGKSQMDVNNNGSSNNSNSNNNNSNNNSGSSRWTLPDNVTELFNGRLFSRMEVTETLPFEKLQAIRESRALAQKQQEEAEEKRKAKQLLDEQDEKEKHEAQNQKQQRELVDAEQALIKELQRSQAQMLRPDAIDTSSTAPLETLLECEEEEIRVSPLDPEDAVVDADGNPIESNIISMPVSPPTDSYPPPTLPMPPHIATQMVWPGDEEHEEDEEVTPRETKPDSGNNSNNSNNTATKTKTLFLSVAREEPDGSTTPIEPFHMEDLPSRIGAAGVRVSILLPVEEEEAYFASSVAQHKERRRREQEERAREREEEDEADKKSEEEDATNIMPDPPKSPLDEVGPFPSPPTKNPMRFQSFIKKMGKNPNTVTPPPPLVEPPPTQSIPQVTVTDVDSQKRRHRPALAKASRKSLGKTPKSSFFLSSSSTSSSLIPHPRSSLSASSSTSPMAALAAAASATPHQRDEETYVYLSATPFSLVMPTYRHGPIRLNRSDLMDNQTDSRNSYDHKLRHHHHHPNIATVEETLDWTAFQMAILGGAGEFRSEVIDYGQISAAEQDEVDRLADWFLLLDIKPERLLTSAEEDTEWVRAVPPPPEASTTAAPPTLTHHTQRTAGSQWTSVSSSTVAGVGAPVPTDVRGLTHSRTTTSTSIATTASGYSSSCGSSNRDSGTPNNAPVISTDPGLTAQTVNQALPFQNSNSANSPYAMSRDNSAAPGLVSNTSSGTNVVGDDITPTQPRTLHSLPLNSMHSVQDVRASFASVASYESMPQSPMADLIMTHGADGKEYVAPMGYNLSHDLGDYLQWEKDNVYAMALEEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRF1</accession>
    <name>A0ABR3ZRF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">MICOS complex subunit MIC12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Found in mitochondrial proteome protein 51</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_000543</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MICOS complex subunit Mic12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031463">
        <property type="entry name" value="Mic12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17050">
        <property type="entry name" value="AIM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="255" mass="27238" checksum="DF6B37A4E5B81AA9" modified="2025-10-08" version="1">MGFTTGFTGGVTLTLSVAYLTVLAHQRNRQRQCDVLRANTSVLRALALADPITAARLATPHAAETPDDLSAAAAAQEFYYPSKPETSRQPRSSFVEELKTRWNTEVEGAVRKVQTTDWIEVRENAEGRLGQLWRQAFGGEEPAATAAAATAAVMNRAAAVTETVKAEAKGLQRAAIAQANEAAAAAKNVANRAVDKGREVLAAETSKAQTAAAQATGQLSEVELALQQRYTGAAEDARMKKSVGELLDERYKHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRG4</accession>
    <name>A0ABR3ZRG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_000565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="292"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="550"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="945"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1049"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="945"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="959"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1082"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1120"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1146"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1157"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1249" mass="134074" checksum="15D421F7B46EAB10" modified="2025-10-08" version="1">MSNKKISNYTSVFRVRLGDDKVASIGNSSTSNAAGNNGTTDSQQQRSADSNNTAGPPIRRSQPRAKSRPVVSCLLCRTRKQKCDRLLPCGTCTRRGDGALCRYGNEGGVSGVNAGSSAAPSSSLSGRGVAATGAGSSSGSGSGHGRRPASSASAGACAGTGGPTGSSIGARQEAQLRLQRLEEMVNGLVSRAPASGSQDGAAASKDGETAAKTPTLAFGDPDPAVTGGWQATEQGDKREPRFEWNMPIGPGAPPPSVGPVASMLGQTPFSGATNWAAVLDSIRDIQSYLGEAAKEDKSRKQGAAENEDGGEQDDDADENMGDNVEEVSEQVAASGQSATNQAQNQQQKKLHNPFLKFVSKPTMYGGVTDPKTVLLPASLSGLPSIPKRPAAAEPAEKVPPLAKSISVAEAQASLPSYTPFQLAEPDGIFSAVAAAPGLASSDQSNPPATSHIALNPPLPKHLADAIACLPPRSDCDRLMAVYFQTSYMTGPFVHTGYFQRSYLRFWRTGNPAAANPISPLLWMSMLASILSMGAMIDGGRQLAWMADREQGASHMDEHGDNAGADGGGAAAGQKKNNDADPELSNEDLILATRLQTLSTRCLLAGDYLAGRQLAVEALVLNAHVRLMQKRDADATQWATFGVIVRLAQRMGYHQVDAPGGSVCGIGGRRLTPFEREMRRRVWYFVESFDMLFSFQFGMPTVVHEDEVATDPPSNLIDDDFDETTAELPPSRPPTDYTTSLYFTVKLKLIRLLRRVMRVAVWRNDKAQIHGAQSYKATVTRITEELRWNFTTLPVRLRMPQHIRDCPFNDASHDIMHRLAAELMHHKAVCILFRDSLSRDIDPDGGVDSKGFTASETKMQRQACLVSALRILDLHTEFEYETRPESMAATVARTGGPLFQASPEPSGGNRGVGRLATDRNMISSLALHDFLLAATILCLDLIEGNRQDQGKKDDPNKNQASESGSSASNEATTAPASSTKNLELPPSLVFAPFLGGGGSSLEERAADRGAKMIALRTAYALWHERRLTSRDAAHAARILGAIVTKLSSEVSDGVPGDKEYDATGNKVRPWPESDSPGWGHWDIAAREQRRKQYEDDLKKQRAERAERAERNKAATTDHNGSQSDTSRSRDASSTPNNSNTPASQTTDSASTGAQSQGQPQAQNPALPPQYQQQQQPQAPPAQHASPSQPPPPPPHLNYAYEWAEPGPFDAVLNDPMNVDWNMVDWFLLDRQLDVEVGSNVWSADLMALEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRI3</accession>
    <name>A0ABR3ZRI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF9">
        <property type="entry name" value="CELL WALL INTEGRITY AND STRESS RESPONSE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224463" evidence="3">
        <location>
            <begin position="28"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="48339" checksum="7ECF212EE1256EE6" modified="2025-10-08" version="1">MVSSALLSAAVLFGAAAEAIQYKPARATDVPIIPADAMSPRPTSPPELRRNALLRRAGSDTTVYYAPDNTCGFLTGDEDNAYTCNDVNAQCAIITISKSGFIGCCDDGQCGGFHLNCIDSSSYYSSSACGSSCKSDSFTLKCTDSDTPYCNSVSINGGASLKVYGYFCNDEAISTMQPILTTYSGETDGRSFSASVLDTDTTLDSTAAETETFDGGSSSTPSPSPSPSPSPSPSPSPSPSPSPTPPAKKSNTGAIAGGVVGGVAGLALIGAGIFFLLRHQRKNNGMQGGVGGAPGAPATGPGGAPLAGAAVAGAAAGGVAGAGSPGMSQVNTPPPQPYYADPSKTPEYAYAGQGSPQPGQQPYFQGQPQPYPPQQPYPPQQPYYAAAAVAPSPERTDSTSPMPVGSSVQDYRMSSISAAGSSPYTGPISPQTTGNTGVSGVGAVPGGHPQVPATIHEAGGNAVGGAQDFNANHHGQMHELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS15</accession>
    <name>A0ABR3ZS15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vezatin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_000791</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
            <location evidence="2">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vezatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026859">
        <property type="entry name" value="Myosin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026858">
        <property type="entry name" value="Vezatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15989">
        <property type="entry name" value="VEZATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15989:SF5">
        <property type="entry name" value="VEZATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12632">
        <property type="entry name" value="Vezatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0965">Cell junction</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin-binding" evidence="16">
        <location>
            <begin position="225"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1902880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="694" mass="76353" checksum="584F6B81F1B316A8" modified="2025-10-08" version="1">METVVFDQTPLAEYLRDEGEDEPTEWVPAITRSSSTADLSAGDDVDSDDASTSALPVTPTPNQRHEPHQQQQPRQRKKTKDDSQNGVDTPPPSPPSPIFAPVGRPMVRKRFRNKIPNPLRVDVRRSTSLSSSLNNRYSRAVASTISRVDNAQFIEKFRYTIITSHLLGAATLGQHQQPTRPGSSSGIGNSDADNNAATLAQDTLDVQVPTATGIVVAVTSAFVLSWAVRWVYLGGIAHLTKKRFVFGLVLVATAVFVGHAYIRQQWLRYVRQSALTEVRAFVTQSHDFDSAASASIAFIKEVELVSRGYRISAPLPPISRIDDRSQSRRCMRLRKVVRGALADVLPKYIQTAEVIKGFAEQTELEMYYHIHDITDFDISDAIQGFSEAEFDDADSIRTLTVLASRFHTIRKLFLCALLALEARGDESDFLRWTTAVEGLRTLNEVTATGYKRIRTILGEAETFPQIATPKAPLSPGRERWRSQLGKLNSLSTGIRGLQAKLALLREESDRSLNEADDITQLGPNLLAQYDSIGQDLKLLTQAWEEGRAALASGIDRNEKRLSSISALLSPTVSLSGLTTVGEDSISGGGTAEDALRALTGGSPLGGSTVGDPDEEIVFEAVSLPPSSRRKSMLTREERIAKMKEDREKRAEAREQADANRGMLRELEMVINLRPKGGRDSLGLPPRTDTNRNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS40</accession>
    <name>A0ABR3ZS40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="46"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="606" mass="64392" checksum="1EB12FB5FC5D1AEC" modified="2025-10-08" version="1">MTMSPDLDEEVAAYESILVILEPTNTSAGSEDLTREIRFTSDNHTVKVGRASKTVSKGLVPDTTNAYFDSPVVSRTHAEISANFVDGSITVTDMGSLHGTSINEKPLEMNLPSILEQDDIVSFGIHVSRGLDVFYPTSCAVGLVRTPVKPTERSRSYCAPDSDDGLSDGADDYNSDSVCSVDVQVINGQRVTATYEIEDTDSSSDDDEAMSVKEIEICPAMEVLPSLGVSKADVDLSDETNEDEEDEDDGEDYGEIAEDDEDEEDDQDDEDDGEDEDEEEEGEEDEGNEEEEDNEGLTQQPDDINGYLMAELQGFSKNSASPLPGKEATPVGGEDSLAAHGLWTPPSITADDVAELSRIAESTFQGGICDSNEGASTNGSLPRSVTAKFDISSLLNPSPPTSSPAKDQTDDNAIPTVYPSIFDAYETLDATVLPNNDMPMKIDTVINQQSTPPRFLPPIVSNPNSFTANNVASASMGLSGASASAAGAEADEGDNEDAEVAWEGIVDDEEENADDSPAMTSAATFVQYKKQRASNKKRKADEMLADIDAVTASTTAAPSAKRPATPAAIATKRVKSRGWAFAEKIGIAALGGAVVLGSLIYTAPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSC5</accession>
    <name>A0ABR3ZSC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L26A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL26A</name>
        <name evidence="6" type="ORF">Sste5346_000025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="137" mass="15564" checksum="113504AAED208F68" modified="2025-10-08" version="1">MAKSNNNVSASRRKSRKAHFSAPSSVRRNIMSAPLSKELREKYNVRSIPIRKDDEVTIVRGSNKDKEGKVTSVYRLKYVIHVERVTRDKASGQSVPLGIHPSNVVITKLKLDKDRESILARIKAGRDQRQKQKEDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSC9</accession>
    <name>A0ABR3ZSC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster assembly factor IBA57 homolog, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAF17</name>
        <name evidence="7" type="ORF">Sste5346_000199</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvT family. CAF17/IBA57 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057460">
        <property type="entry name" value="CAF17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25455">
        <property type="entry name" value="Beta-barrel_CAF17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="CAF17 C-terminal" evidence="6">
        <location>
            <begin position="310"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00093447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00093637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="453" mass="47747" checksum="9412B6AF10077E75" modified="2025-10-08" version="1">MNAPWLAVPRSLQSVAAVSRSTSASALRSSASSSSSPLNICRTCRRSRTRTGVPSRAYSSSAGAQVPTAGAASLASRRLISVSGPDAAKYLQGVITSNILRLQTTQDDGSAAVAAPQTGLYSAFLSAQGRVLHDVFVYRDTLGVGKNASNSDASFLIEVDAESATILAKHIRRYKLRAKFDVRLLDAGEVNVWHGWGLPEGQQASSFGAESDLIAHNDTRAPGLGWRFIALAASTSSTLRPQIELDVADESAYRVRRYLLGVAEGQREILHNQALPLESNIDLMGGIDFHKGCYVGQELTIRTRHRGVVRKRILPCLVYGPEDEQPRSLAVDAHGAGTGLADTIPGETSIGRVGKKGRSAGKWLSGVGNLGLGLCRLETMTDAVLPGEAAAAAATAAATFDPTSEFVMNVVEKVDGDADGEAEGEAAASAPTTVVKIKAFVPDWLRQGLTPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSL1</accession>
    <name>A0ABR3ZSL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease III homolog</fullName>
            <ecNumber evidence="7">3.2.2.-</ecNumber>
            <ecNumber evidence="7">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <shortName evidence="7">DNA glycosylase/AP lyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NTH1_1</name>
        <name evidence="7" type="synonym">NTH1</name>
        <name evidence="10" type="ORF">Sste5346_000494</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="7"/>
    <dbReference type="EC" id="4.2.99.18" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03183">
        <property type="entry name" value="Endonuclease_III_Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030841">
        <property type="entry name" value="NTH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="9">
        <location>
            <begin position="247"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="474" mass="52145" checksum="46ED10DA6B26768E" modified="2025-10-08" version="1">MTTATVTAAGPQRRRSTRMASTSLARFRYRENDNSDSDSGVKKEEREVDDGDSDHKPSDDESSLSELSFNSDIEDAVAAPKRKATRGARTRTTTTTTTTTTGSAATGKRKRAATTTTTVVTTLPTHKKRNGATSTVNSENYVEIKGEIKDEELDEQDLSSIQQKTASPRKARKPARVITTKVAGKEDETHVEPPTDWELFYNLVKEMRMPGGPAANAAVDTMGCERLALESASPRDRRFHTLVALMLSSQTKDTVNAVAMARLQSELPPHEPGAPPGLNLENMLAVDPNLLNQMIWQVGFHNNKTKYLKQTAVILRDQWGGDIPPTAEGLMALPGVGPKMAYLCIAAEHGWNRVEGIGVDVHVHRITNLWHWQKPGSAAAKTPEGTRLSLQSWLPRDKWKEINWLLVGFGQAVCLPQGAKCGDCTLGLRGLCRGANRKKVLDGRKRRRELGLEDLGDDEDSVIKDEVKDEEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTA1</accession>
    <name>A0ABR3ZTA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-lactate dehydrogenase (Cytochrome)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000099</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF104">
        <property type="entry name" value="CYTOCHROME B2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="9">
        <location>
            <begin position="107"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="53908" checksum="0E4D367AC794AE08" modified="2025-10-08" version="1">MPSVADVAAHNSRSSCWVIVSGKAYDVTEFLDEHPGGARSILRFAGRDATAEYEPLHPPGTIESLPKDKHLGPVDDLTLEPEPTATTSEIQTSTSPLIMTTSAPVILPLSACMSLEDLAQVAAIKLSPRAAAYYHSGAETRYSRDRNRRDWSRIGLRPRVLINVGPTPRMRTNVMGFDSSLPIFISPAAHARFGHPDGELCLARTAARMDIAQCVSTYASMTAPDIAAEFFNDPHKRGGAMFFQLYIPRVKKDAEKLIAVAKKAGYQALVVTVDAPVIGKRDDDDQFQALAAAADGGDSENKGKEDTEETLPPLPSQEPGTLRAAHNATFEWSDLPWIRHCWGPEHPILLKGIQTAEDALLATQQIGPDGKRLVDGIYLSNHGGHQLDYAPTSVQTLLDIRRRAPQVFDQLPVYVDGGVLRGTDVIKALCLGARAVGLGRGFLYALSAYGTAGALRAVQILSDEIQTTLRLLGVADVAQLDERYLDLSEFGIERAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTP9</accession>
    <name>A0ABR3ZTP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30964" checksum="12F0942C1DA34401" modified="2025-10-08" version="1">MADLYAGRSEIWGVDLAPFQPHLMPSNAKFQSLDIESHWMLGAASWDLIHIRCLNGVVRNWSSLYATVHSHLIPGIGHIEHVEIDWTPRQISHEVPGSSPSSSSSTSSSLAAWADILLSCMDRTSRSLRVDPAETRTALHEAGFVDVRQDTYRLPFGRRAPTDSSSMSPTASSTTRTRTSLPSLSSLSSPSSHSRSVFPLSDDDEEDEEGDDGSHDSSRNGRWSGGGVEKWFPRAFDLWLEGLTLMPLLRAGYDLETIYRWIADVRREVADPSCTASCTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUL6</accession>
    <name>A0ABR3ZUL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">YET3</name>
        <name evidence="15" type="ORF">Sste5346_000229</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041672">
        <property type="entry name" value="Bap31/Bap29_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18035">
        <property type="entry name" value="Bap31_Bap29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="13">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Bap31/Bap29 cytoplasmic coiled-coil" evidence="14">
        <location>
            <begin position="162"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="163"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1903600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="211" mass="24311" checksum="6216427783DD04E0" modified="2025-10-08" version="1">MTLYYTLVFMLLMAEMSLFVVLIVPLPFNLKRKIFTFLSENPIVAKIQYGMKITFIFILILFIDSVNRVYRVQIELGLSSENGANGAAIIGRDRLEVQARKFYSQRNMYLCGFTLFLSLILNRTYTMILEVLRLEEKMKKYEGTEKDTKQSEKLTQAGDFAEIGKLKKELAKKDRDIETLKKQASGLQREYDDLCEKYGATQAPAGPKKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZW45</accession>
    <name>A0ABR3ZW45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ABD1</name>
        <name evidence="14" type="ORF">Sste5346_000650</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for methylating the 5'-cap structure of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="13">
        <location>
            <begin position="237"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="440"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="32"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="91"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1903364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="605" mass="69755" checksum="C80E4DB9E019B3F9" modified="2025-10-08" version="1">MADSYEPDRRSHGDSDRHQDSSNKRRRSQSPDQRDRRDHRDDRRDDRRDDRRDDRRDDRRDDRRDDRRDDRRDDRRDDHQPKRRLQSYASRRNEEGRDGRDNRDSRDNRDYRDRDRDRNDYDRRANDELPQPFDARALEPAKRRARSRSPGGGSGAGSGSGAGGSGAEQPRRPKRPGQRARITDTEREAIRQRALERERQIKEDQERQQQRALIDDVVRSHYNAVPERGREWRKTASTIKGLRSMNNWIKSCIIQKFAPDEEFEERTRNGIGGAGQHELLVLDIGCGKGGDLGKWNQAPQKVALYVGLDPADVSINQARDRYREMTTRGGGGRGGRGGYHNRGPPRVFDGRFIVKDCFGESIGDINIIQEVGFDQNPMSRRGFDVVSMMFCMHYAFETEQKARIMLKNVASALKKGGRFIGCIPNSDVLGEQVERFHIKQAEKKKAEEAASTAAPHAAEKEDNEAKDGKAEEGEDGEIKPEAPTQTAEWGNSIYRVRFPGDTPADGTFRPPFGWKYNFFLNEAVEEVPEYVVPWHAFRALAEDYNLELQYHKTFPEVWESEKDDRTLGPLSERMGVRDRNTGELLVSKEEMEAAGFYVAFCFYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGV3</accession>
    <name>A0ABR3YGV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000136">
        <property type="protein sequence ID" value="KAL1887205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="138"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="461" mass="50088" checksum="41C9D11C2A38280A" modified="2025-10-08" version="1">MTSKPFHLAIVGGGITGLALAIALKKRGVQITIYEQAAAFGEIGAGVGMHANAVRAMKIIDTELLAAFERVATRNAWPSKKNVWFDVLDGTAEEPASSPELLKPLFTLIGHDDGHAACHRARFLDQLVPLLPEGLAQFGKRLLSIDDPEDTDIPLTLHFEDGTSAKADAVLGCDGIKSRTRAHLVDRHDQEAAKPKYSHKFVYRGLIPMKDAVATLGEERSANSMLWMGPDRHALTFPVNHGQTLNLVAFVTTDDPWPSKDAQQLTLPATRDDALRDFAGFGLNVLGLLRMTAPQLERWGLFDLAENPLPQFFRGRVCLVGDAAHASTPHHGAGAAMCIEDVAVLAELLGDPSVTDTVGVQAAFAAFDSSRRGRDQWLVASSRRAADMYEWRARGRDFEAIADEVCARQAYIWNIDLDASIAAARKDLANRLALGLPTAAAPDKTVPFPPDIDFHLRDRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGZ5</accession>
    <name>A0ABR3YGZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_010135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058758">
        <property type="entry name" value="UBA_RNF216"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF42">
        <property type="entry name" value="FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26112">
        <property type="entry name" value="UBA_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="365"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="872" mass="94448" checksum="8E0A8DD85A38B099" modified="2025-10-08" version="1">MVFAGLLGSTKQPRRRPSSVASGRSGFLRPGSSSSTRTDGEKEKEKDKGLEDAIDDDEDDGGGEDDANDAASIRTTNSARSARSGRSARSGRSTAATSASPPPLPPPDFIADETHLAPLFPEAPDLRELNNSLAALAVVFPDVQVDVFREMLTSFDGESRLALVADALLKNRATWVKGRWRIADKDKPPPPPNPSTPPSSSEPSSSSSSSTLPAPTIPPISTADRFRTPEYKKAVKTLASHEFMGLSRSTINAVLAEQNYAYLEARRALVQMSSKSWRFTISSLFLRRKPVTCTEAENHPLIVWKSSGQGSIIPTIKATGSAELDRELYTALVAPLRIQQRAAQEDADRTMAAALNTAEAEAIGATYECACCFTTATFEEVTTCSNGDADADEGAHIICFRCVQHSVREAVFGQGWARTIDTSRGTLWCPAVSQTECGGVIPVDHMHRALLDEKRGADTLHHLERRLADHSLVGSGLPLVRCPFCAYAEVDDIYVPFYEAPLRIRVDSLYSLAFILLVSGVTHVLILPLLVLLVLVTVLPGFMAPVGLASWVVSAWSALKFNFGGLGNNNDNSTGPLQRRRTSLPSKPSYFREQLSAAVTRFRRRRRGQQFRCQNPACARVSCLGCSKAWTDIHVCHESSLVALRTQVEQAMSMAIKRVCPRCHTSFVKTVGCNKLTCPCGYKMCYVCRKDISGNDGPDAGYRHFCEHFRPHGDGRPCNQCRRCNLWETEDTEAVLQAAREEAERKWRETERRELSLSERAYLETGIAIGGGTAAGGSVVSSGNAGALGTRVGAGGHGHGHGIGGAPAGAIMVRRVITGAVSWATSPLSWAFLSDKDTDGPPSAVDAFDTANQPRFPTLAETLDWLLESVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI70</accession>
    <name>A0ABR3YI70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trafficking protein particle complex subunit 6B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="26957" checksum="FC4C79C82A798E0E" modified="2025-10-08" version="1">MSFDPVLPPFNASDPGATFFNSSCLDFLLIELVPMAYRVTNELEAGAQAKSLAVAAAEAGLEGAQQSQAATAASQGVPDKAAAAASTSGTGTATGTVTTTAGPNGPAGGRRLLDEDEERDAVFYRLEMLGYRVGQGLVERFSRERPRFHDTLDVIKFLCKDLWTLVFRKQVDNLKTNHRGVYVLTDNSFRPFQRMSTEAGGQAVVRAQPFLWFPCGIVRGALAALGITATVQAESNELPGAIFQIKTIPVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIB4</accession>
    <name>A0ABR3YIB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000101">
        <property type="protein sequence ID" value="KAL1888069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12170">
        <property type="entry name" value="Uncharacterised protein PF07075, DUF1343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008302">
        <property type="entry name" value="NamZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048503">
        <property type="entry name" value="NamZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048502">
        <property type="entry name" value="NamZ_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42915">
        <property type="entry name" value="HYPOTHETICAL 460 KDA PROTEIN IN FEUA-SIGW INTERGENIC REGION [PRECURSOR]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42915:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN BETA-N-ACETYLMURAMIDASE NAMZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20732">
        <property type="entry name" value="NamZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07075">
        <property type="entry name" value="NamZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016719">
        <property type="entry name" value="UCP016719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidoglycan beta-N-acetylmuramidase NamZ N-terminal" evidence="1">
        <location>
            <begin position="53"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidoglycan beta-N-acetylmuramidase NamZ C-terminal" evidence="2">
        <location>
            <begin position="269"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="47845" checksum="1CA497A83E842F3E" modified="2025-10-08" version="1">MKGLLATGLAAASFAAAHPGHSLPPATLFQPTVKTGLEVLIESNYKQLAGKNVLMLTNPTGITTGLELGIDVMVQDGTVNLVGVMGPEHGFRGTSQNGGGESTFVDAKTGLTVYDAYNVNTTVLTSYIAESGADTVLFDIQDVGARFYTYIWAMYDTMVAAAMSNVSYVVLDRPNPITGMNAFGPVLNESFINSYVGRRAIAQAHGMTAGELAKMFVGEGWIKETAGGADLTSLTVIPMKGWNRHMTFAETGLPWVIPSPNMPTVDTAMMYPGTCMFEGTSIAEGRGTTTPFEIIGAPWTNETWTTTMRSQNISLTDYRFQCFTPVSNKFENEVCCGVQTYLRPQTKEDYANLDPVYIGLNLLWAARNLYADGSTSGSGNTTNSFHWTFNGASTTTYDVDVLTGSTLVREGIEAGLTPDAIREAWTPALDVFKKKRKHYLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIP6</accession>
    <name>A0ABR3YIP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycoside hydrolase family 30 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009904</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039514">
        <property type="entry name" value="6GAL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14587">
        <property type="entry name" value="Glyco_hydr_30_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Endo-beta-1,6-galactanase-like" evidence="4">
        <location>
            <begin position="15"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="5">
        <location>
            <begin position="278"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="42055" checksum="A5FF6150B3C5929C" modified="2025-10-08" version="1">MNSIEPQAPTDGKPVYTWDHSASNQVWLAKTARDEYGLATFYADAWSAPGWMKTNGRDDEGGYLVKNKVADYVDYLVEYVRAWSSEGISLAHIGIVNEPNVVKEYATMGLGNETTNSTVATAFDIIRPLRATLNLSTGISCCEAQGWSMARDLLEEVRPALDDLSVVTTHAYKGDPAAPDVPLNTTLPVWITENSPIMHRLNFSQVWHANSSENEGLVWANNLHTALVDGNVSAYLYWIGAGPSGQEAPLVWLADDGGYKVATTYWAMAHWGRFIRPGSRRVEVERSEAIKTSAYVNTDGSVVIQAINNADRNATIFLLAPDSRPRQARSITAWLTDNSHHLQNIGTSYPENGQALDAVLPPRSLTTFHVQYRWLKTDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIP7</accession>
    <name>A0ABR3YIP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="273" mass="31558" checksum="A4FF167917E7309E" modified="2025-10-08" version="1">MIDLIIHTDAPAEGILPLPNTTYSSSDAWFTALADMHKAQFAFQRRDLVEDADDARDKYVARQLFRQVAAEGRYSPSDKDDSDQPRFALYSEDLRPANILLDKDDNIIGVIDWEFAYAAPLSFSSCPPWWLLMEEPESWSPGGLAGWQETYEPRLQLFLSALEGVEKDQTSHSSVGEPLSRRMRTSWTTKCWMRNYAARRSWAFDFMWWKHLDEAFFGPNEDQDHKPRLTRLSEAQRNAMEALVQEKLKEDQDTEITVWTGKEAVSHLAKYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY4</accession>
    <name>A0ABR3YIY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF59">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="35"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="538" mass="59314" checksum="0B9113FB0F7A0B62" modified="2025-10-08" version="1">MSSKSYFGFDVLVRRVKNIQQAPREIIVNPRLLGTAFVFAFSGFPAVWDQGSSSVLPSLPGYDAFFHVSTGANADLIRDLVSLVYVGYAIGSAATFFINDRIGRLWSYRLYAFIYIIGLIVSITAPSLAGLNASRIVTGIGIGALTVTGPMAIAEISPDEIRGMLTSWFGVCMSLSLISSVFCVYGVYIHLAATRFQYQVVWMVPILAMVVVVAGSFFCCESPKWLMMVDRYDDALAELVRLRGLPADHPRVQAEITAIQDAVRAAHIDTTSEVRRIKQIFRDTFTVSANLRRVQQSLVSYLLAQLSGASQITSYLVPIMTLMGVTSSTEEKLFLSGMYGVAKLASVLLASFCIIDTLGRRNSLFIGISLQIISDVFISVYIKYSQEGHVPLAVSQAAIGMLYIHGFGYCIGLFLLPYVFGAELWPDHLRTFGGALGQTFHWMFIYAMNYGLPSLLTKTHNWGAFLFFAAFGTVALIYVFFMVPETSELSTEEIDTIFRGPWFQAYKTNRLILDGVVDGKERPESVIGDSKSVANEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKH5</accession>
    <name>A0ABR3YKH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">sterol 3beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ATG26</name>
        <name evidence="15" type="ORF">Sste5346_009574</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="14">
        <location>
            <begin position="539"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="238"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="449"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="708"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="913"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1494"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1735"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1169"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="31"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="384"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="781"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="843"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="913"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="927"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1494"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1743"/>
            <end position="1768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1888367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1818" mass="197740" checksum="1654B38443EF345D" modified="2025-10-08" version="1">MVPPIDKAAPTAATSHSQTPTPTQTPPPLSTTPSNVSNRNTNTSNTTTSSSTATLSAPNTATAAASLPAPVSTAASASPSPGPSRTVSGTASPTTPSTSTKKHHHHKHSHSHGLRLPSRLSSQSTSALASALAASPNPLSGSSPRHSEDETGRSSSRHKFKRLVKRRHESASGATGGSQRTPKTMEFPERLQQEDDDAGDEEVIRPIVSGNGVFYNMNQSVFSMLAAAGSNIDFNNRFGTHSSDEDDGGDGEGGDDGDDNDGHGRRLGGGDGAATTVLPATGSSSKKSGKKPASDLSQSTIFTRHQSSGSTSSTGGKDGDRRSRFSDSKLMRSLPSLKSKLSSSKRRSSSGLSSKSSKNAGASGTGSSRILEEDEDADAEAESSGGTPSSTQTRLPRGSGATSEADVVVSSERGSNSPSIRVTRADRSDSVRSIPVMSRMLEAKEQAALRPSFDIDRDRKSSDKDKDKRGGGSDLVDVEDGGPSMLARRLMEIFEFDKPEEVIEEYPCWLLQSVMLQGYMYITSRHICFYAYLPKKANEVAKSGHLAKSGKRNPRYNRFWFRLKGDVFSYYRDSKALYFPHGQIDLRYGISATLTDKDKDGTHFQVVTHHRTYYFRADSAASAKEWVKSLQRVIFRSHNDGDSIKISLPIENVIDVEENQAMVEFTETCKIRVIDNDETFAIDEYFFSFFDYGKDAVRVLKILIDANNNGGDGDDQNNSGTGTPHRQHGRRLDLPSAGQGTDDRFSQDSTGSAAFGAGQERISMSGSGSKPPTKLHDSVRATLFPTPPTAASSPRASGEIPRASFDALRSSFGPSRRSLDMNQALGGSGSGSPRRSFSDRIKGSSSQQRKVSSRSQSGTQHQYQQSSDLQDSADSFMQSSVEDPSQISFSNMAASSSDDPSASQILHGSEVFQNPTVDAGSPSSSSKPRHNIPKPHLPHHAATTGHIRRVNDQNAYDAGETEEGLAQNLARLGTYPLQRAGAYAGWLNRQSRRVSTMLATESMGYVEKVSGMWRGGRQHYDDAALIPHAEDGNPDGEPGMSVADAIVSNEHFREHFALPDTEKLQATYFGSIMRVLPLYGKIYISQRYFCFRSLVPGTRTKLILPLKDIENVTKEKGFRFTYSGLVVVIRGHEELFFEFHQADMRDDCAITLLHLLEKARSMKESGILNEEDKADAELALAERDALKEAREEAAARMDEHAETPAESAANAVSAAKAVVSAEAKEERQNRKILRQSALMAEAPTILFDDPKASFLNFKPAKPLRITCLTIGSRGDVQPYISLGRGLLAEGHHVRIATHPEFEGWIRSHGLDYGRVEGDPGELMRICIENGTFTFQFLREANSKMRTWLDELLASAWTACQGADLLIESPSAMAGIHIAEKLQIPYFRAFTMPWTRTRAYPHAFLMPERKMGGAYNQFSYTMFETIFWKATAGQINRWRNKMLGLRNTSLEKLQVNKVPFLYNFSACVVPPPLDYSDWIRVTGYWFLDEGTGIKKGNDPKEKDGGSESQDKTAVEKKDPAWSPPQDLLDFIAKAREDRKKIVYVGFGSIVVTDPAKMTQEVIDAVHKADVRCILSKGWSDRLVAKKDTTVDATVAAPPPEDELPAEIFPIKSAPHDWLFAQIDAAAHHGGSGTTGASLRAGIPTIIRPFFGDQFFFGQRVEDLGVGICLKKWGAMSFARALWEATNSERMIRKAAHLGEQIREENGVDTAIQCIYRDMEYAKSLVREKAVKSGMLRSSVASAGDESDADGYDDDDEPEESWTFVGDDDPMQQSMILTPEAGGSGSVSPAAGQSGAGAGAGGGGYKALGSRILGIATQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKX9</accession>
    <name>A0ABR3YKX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC multidrug transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_009563</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="836"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="880"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="962"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="161"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="521"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="842"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1158"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="756"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1284"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="778"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="800"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1285"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1296"/>
            <end position="1305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1428" mass="156371" checksum="EE95CBB3682AC5AF" modified="2025-10-08" version="1">MASNNGKTFPPRKWYRRVPFLSQKPIEAKLTQRRQKKQKHSLSGAENGANDANNDNTYETVTPEAYANILSIVTFDWLGTLLRTGYSRPLQADDLYDLPGSRLTIDHADRLEKAWAARLKANNERQPAGQWLAWRPFWSRRTSNATVLALALNDVCFRRFWTGGLLRMLGDSTQMISPLLIRVFIQALDNPSQQAYRAGFGYAVGLFAILAFSVVTNIHGFYRAATTGILLRASLMHVIYRRAMTQLTHEAKLRENLSTGKLTSLMSADVSRVDFCCGYFHAVWTSFIQIALCLGLTIWTLGYSALPGFGLLALFYPVQSFMMKNLFRLRRNSMPYTDKRIKAVVEAVSTIRLTKTNAYEKSIMARIGALREDEVVYIRKRMLLRALNIAVSFTAPTLASVVSILTYAATTGNGMSASVIFSSLTFFLLMRTPLGSLPIAISTLADAQAAVERLAAFMVASDNGTARDAALRDTLAEKGRSNGDHDNSFIVQLRQATFWYHDSEQLRAEWERDNADSGSVDEKANVEIQAATASSSLFIDTLNVKQGQLVAIVGPVAAGKSSVFRALLGDMHLARAEACAVNLDASASSSPLAYAPQTAWLLSETVRENIVFGRPFDAAWYDEVLNRCCLHADLEILADGDMTVVGEKGVSLSGGQKQRISLARAVYGRSQLMLLDDCFSALDAHVGSRVFDSVVNQTRHKKESTVVLVTHSMVFASQADHVVFMDKGRIVEQGSFSDIKSGGGLFSEYLRSATATRTDENEDAETIGAEAGPSTKTAKSDNGSKDATKILTADKTPPSTEKKEKERGKEIMQSEERLVGTVSGKTYLHYLKFGNAWVTVPLFIISIAIFQGSSVVSALWLSWWQTDKYRLSEGAYMGGYAAWGAGQSLGLFAMSTVFAFFCFWCSNHLHAASLSGILFAPVAFFDTTPQGRITHRFSKDMDAVDNIVGEQLRIFISTLVQVIGTVIVVSIILPIFLAIAAGVLLVYTWTGMYYRPSARELRRLNNLLRSRIYEHFNESLSGLPTLTAFGLVGGFVADNARRIDTENTAYWLSIACVRWLNLRLDLLGAILVLGTGLLGTGLRDHISPSTGGVVLSYMVTAQAAFGNMIRFSAEIENNMNSIERLLHYAYDVPQEAAHDVKRVDADLKAQAWPSKGRVQFESLTLSHRPELDPALRNVTLDIRAGERIGIVGRTGAGKSTLITALLRLAEPTSGRILIDGVDIQTMGLHTLRSQISVISQDAVLLAGTIRYNLDPFQQYDDAWLAACLQMVGLGELRIQEKETSEAVQVSSEASSDTGPASSDDISGTAPVLHLDSEVKENGANISHGQRSLISIARALVRKSKIVILDEATASIDGRADRQLQVMLGDVMGNATVLTVAHRLDTIIGACDRVLVMEAGAVAEFGSAPELYAKAGLFRVLCDAANIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLR8</accession>
    <name>A0ABR3YLR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11887">
        <property type="entry name" value="SH3_Bbc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057402">
        <property type="entry name" value="AIM3_BBC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035552">
        <property type="entry name" value="Mti1_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46026">
        <property type="entry name" value="RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46026:SF1">
        <property type="entry name" value="RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25459">
        <property type="entry name" value="AIM3_BBC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="395"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="495"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="658"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="708"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="719"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="802"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="814"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="868"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="923"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="978"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1029"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1307" mass="138497" checksum="DD5B9B282E33A909" modified="2025-10-08" version="1">MYKVKAIYEYISEHDDDLKFPVGQIITVTEEEDAEWLVGEYTDDAGNHNEGLFPRNFVEKYEPVAPPRPTRTRTKRDSEIPAAFSPSAIPAAAAASAAADEPTSPPAAPIPVPAAAAPPPAPAPAPAPPSPKEVPQPVEEEQEQEEEEEPETVPEPPKPVVKAAAASAPPPPKAAEPTLPASPVAASKAPEAAHPPPPAASKPAPPPVSEKPSGNSFRDRIAAFNKAAAPPITPFKPSGLGGGPGSSNFIKKPFVAPPPSRNAFVPPPRDVPTAKVYRRDEDPEIKEREAENLESAEKAGLVPGAAPAGASSGGGGNGDDEDEPKPMMSLKERMARLQREQQEQAQRHADAAAKKEKPKRPPKKRLESYDSSGAAASAAGAAATTPGDEAALPPLERKSTSDTIGRRSIEEPAASHPPRVPHAPRRKASKDPGSAEAQDGNDADMSGAGDTTEGQDDELTERDDSDDKSRRPSRTIPIIVPSERRSVEHTRAAEEPEEADEEEEEERAPEPKAAKAPNDDNEEREASEEEGEEEDETDPETRRREELRARMAKMSGGMGMMGMQGMQGMFGAPPPPAPKKKKAAAPAAPAADEATSPSTRAPPVPAMLALPGMIGRRSEDKPAESVPDEEDEKEEEEAPQPITKESRTPSIPTRGAAPPIPGSRPVPPPPPPTAAADIRSQSEGSVSDDELSEAQRDPLETPRGEPSQLPPPPPPPASAPKAPAVPTSPRPTSSGQRAAEAAAASPSSPTSTQNKRASRLPPPIPGAAPAPPPPVQTRPPPPPPPGALSRQSTADMRSPLSPSRPQPPAPPGGSDDEEEEEVTEYEGDYDTDIANPVSHKNSLKAHARDSSLEDNASLKSPTLEKAPSFPPPVPGASRAPPPIPNQPPPPPSLPPTAPPNIPSSQPPPRPSMGDKRRSVDVPRGPPPPPPPPPTSSQTPRYDDDYDPYSYSAQPTSPGVALPGLSSGAPKSFMDDSYTTPDLSLSLSGGSAGTVTGSRGPPGPPPPPPSAPAPSAAIHSSRGARQSTDVSRGGVSGVRRSLDVNRPSMETGHVANDLDLAPHSGWWLQPNGLPPQLQGRKDIFFESEQSQAAKRGGGVEITRDLYVLYVDYSQTVISVRFDPADSSDVSLEQRHEPPPRSLRQDQLEQSYERFGRHIADSILAKKDTIVGDGAPQTLVLGLIKPFRDALLPVGTRAYGALVYSNLANASTSQNDEIRAGDIITLRNAKFQGKHGAMHAKYSMEVGKPDHVAVVGEWDGTKKKVRAWEQGRESKKVKLESYKLDDLRSGEVKIWRVMPRSWVGWEGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLV9</accession>
    <name>A0ABR3YLV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell wall integrity and stress response component 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">WSC4</name>
        <name evidence="9" type="ORF">Sste5346_008969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF6">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046027969" evidence="7">
        <location>
            <begin position="25"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="34357" checksum="8B31843D8D079642" modified="2025-10-08" version="1">MAPSYQSALYGLLFTSTLLARSYAEPSVPMAYCASINTGSTSTNTSIYQSDGLCYDFCNDDYAFAVIQGKNCWCSDYTPSKSSQVSTSECDLSCAGYPSDVCGGDGLYGYMALNKSPSGTASGTSTPSPSKSSSSKTNAGTPTVQTVTAGGVVQTVTVTPSAGSGDSSAVSSSHKGLSAGAAAGIAVGVVAVAVIAAVVAFLVWRRRRQQKEPEDALFVANNPKTPSPRGTSPNTSNSPKVSEVSSAPAFARKVGEGQWESDQSGRRRSTLMPIDPRIDPSFSGIYAHTDNKSRDSVNSLRDDHDYSRRVHQPGRVLRATNPDPEVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM63</accession>
    <name>A0ABR3YM63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET8</name>
        <name evidence="9" type="ORF">Sste5346_009280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>precorrin-2 + NAD(+) = sirohydrochlorin + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.110">
        <property type="entry name" value="Siroheme synthase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3280.10">
        <property type="entry name" value="Siroheme synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330:SF1">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="8">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="7">
        <location>
            <begin position="155"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="252" mass="27515" checksum="02BFD2F6C0C20C74" modified="2025-10-08" version="1">MAPVFPEVQGGGSLIIAWQIRGKRVVVVAAGRILHCLNADAAVTVVAPLSGLNPEVAYRVSQQQVQHVDRLFEPSDLDGADMVLTAVDDPEASTRIWKLCKEKRIPVNVADVPPECDFYFGSVHRDGPLQIMVSTNGKGPRLASAIRKYIAKLLPKQAGQAIDSVGELRVKLRRMVPGPEEGPKRMAWMTKVSDAYSFEDLCNLTDEDVNNLLRFYASGNVPPLDILLSMRGNPDLSKIDVFDGSFGFSIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMH1</accession>
    <name>A0ABR3YMH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="276" mass="31099" checksum="2E1BDADD02F2456E" modified="2025-10-08" version="1">MKILQASTTRGGATGLLSKRVFRLLPNNSQQGPISDIEPLTGQQDGTITTSSNDLSNHVYQLLSGPIFAFYCRLQALSREIAKLTLYHRSRTTSRDQQEVVDRMAALKEDLHALWTSRSVTQCQPADELHAQLAPAIAQRIVSLIAICNAAYYAELVEMGRQLGDPLSRLPDSRDALHKIRETVDREVQRGAGTSHTSTVNPGFLRPLFLYAIESTEPHQTQWAVDRIAQIEPRIYRGQFFSTFAKELAGAQIEKERRVTSRYFCIWYFGVSPPYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN42</accession>
    <name>A0ABR3YN42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045752714" evidence="3">
        <location>
            <begin position="21"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="288" mass="26863" checksum="E79280C1D09BE798" modified="2025-10-08" version="1">MKITSYGVVAVLAGVSAVDAALCLPSWPTHWRSTSSSASNTALPESSSSTTSSASKSGSSAVDSNSEGPTGSSVGPSGSSSASSVPNSRSASASSTASSFGSSSAFSSQSSVYISSSVGPVQSSSVSVSLSSGVSSGSNSEGPTGSSVGPTGSSVGPSGSPSVVSPSGSQSVGPSGSSSVGPSGFGSSSVVSPSGSQSVGPSGSSSVGPSGSFSVGPSSGSSSIGPSGSSSAPSGSQSVGPSGSSSVGPSGSSLGIVGLRFVRFIGFRLLGLRLFGIICLGVVGLRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN66</accession>
    <name>A0ABR3YN66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009027</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="54"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="607" mass="64775" checksum="5635FCE5D064BDDB" modified="2025-10-08" version="1">MSAVQEDKNGVHQAVTNLEHPALADKPATDTEASPPVVAANNDDEETVSWSTLMAVFFMGMSYIPCISAGLLLPTGILQQIGQTLGDTDNILWIPGGWSVASAVSFSIAGGLSDIFGRRYVLLFGQLLTLIGGIVGCTANATTTVAAGTTIIGFGAGVIFVSYPGIQELLPNKYRGAGIGWTEFCINIPWGALSVYLGTQLFVHASWRWCYYIVIIYSVFVIAGTAYFYYPPSRPQHDYDKSRWDEFRELDFIGLGLFAAGLTIFLVGITYLGRSNYSIPMVAATISVGAIVFAGCFAYDFSPIPKHPIFPRHLFALFREFTVHLIILFVSGMIWQGVVTLGPQGTLYMFTNDPIQIGITMIPANFSGVLGGWILPSLVHRIKHVRLQILLALVIQTAFTGAYAAVVPTNKAAWSAMQLFGQSCFTWVTSLAYVASGLFVPVEELGLSAGLLGTFRSAGGSVGNAVFSTIMNSAVNRNLGGNIVAAALGAGFNPSTNGSLTALVPAVIENAVGVPHAFDTVPGGVSDAVKAATSLAFRNTYASAFRLVFYTMVPFGALALGCAWFVRDPSHLLNNHVAVHQEKEVLSGIDHRHENKTAASSGGVRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA0</accession>
    <name>A0ABR3YPA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="101"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="540" mass="58707" checksum="6D5A019483E24C39" modified="2025-10-08" version="1">MLESLANTPLGSFAHWVSGGRLASYPEEQAGFYLPPSPPPSQLQSQPPICTPSSGSEKECSEDTNEADIESGPPSVHVVDWYGDADPANPLHWSGFQKFRIFFTINYANSAIYLSSSVFAASQAAFETAFHTTPMVTGLGISLFVLGYGVGPLFISPLTDMARIGRTPPYLTATFIFLILSIPTATATSVHSFMILRFFQGFFGSPVMTAGGASLSDIASDSIKPLALYTWACSGFAAASIAPIVSGFAVPVLGWRWPLWEVVIVNAPTLLFLLLLPETSPRKILYLRAQRLRKCYPGTNYHSKAELEHRTSVQLLLWRSLIVPWQMHALDPSILFTSIYTGFVYGIYYSFFEMFPIVYQGIYGFNLGECGLVYLAIVVGVVLAGIPYCSYVYYYVVPRDLAGQVQTPPEDRLLPAVFASLLVPTGLFIFGWTARSEVHWIVPTIGAGITSAGMVVIIQCVFVYISLSYPQYVASVFAGNGLLRSLIAFAALLWSRPLTDALGVARGSSLLGGLCVGGVMGLIILYKYGATLRAHSKFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPX2</accession>
    <name>A0ABR3YPX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRE10_2</name>
        <name evidence="8" type="ORF">Sste5346_008250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF51">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="221" mass="24961" checksum="6F6157AA363F5070" modified="2025-10-08" version="1">MAAEDVSKYLQQSHERVFESNRAWAAQKKGEDPTFFDKLAAGQTPEYLWIGCSDSRIPAEQITGLGPGEAFVHRNIANLVCNIDVNVMAVVNYAVEHLHVKHIVVCGHYGCGGIKAAMTPKDLGLLNPWLRNIRDVYRLHEAELDAIKDEAARYNRLVELNVIEQCRNVIKTAAVQKMYAKNGFPIVHGWVFDFHDGLLKDLNVDFKKILADIQKIYNLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ36</accession>
    <name>A0ABR3YQ36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arylsulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047443908" description="Arylsulfotransferase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="561"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="70793" checksum="DAE3B44E74148B8F" modified="2025-10-08" version="1">MKLRWLVLVLQAIGQLPKSTASPTSTSSPSSTGPFFGTPNDAFWYDWGRYGLHPEQHYESFSASPPRPYLLQHDKRCSATVTDDDNVDGQDLIFAAPRGLAVTAPGPIVYDTRGHLVWMDTRWGEAMDVKVQQYNGEDYLTFWHGTDNGTFGEGQYYMLNASYDVVRTVKPAPTADGTQLLGDLHDFVITEAGTALMTIYQTRPRDLTQKYGIQSGWIFDSLFQEVDIATGKLIFQWRASDHFAVEDTFAPLKRGFGKHAAKAFDFFHINSVAKMPTSGDYIVSSRYMCAVICVSGTTGDVLWQLGGRRNSFKDLSDGQATNTHWQHHAVWHEETQELSVFDNGAYDKLETAEYSRGMRIKLGLDSKPPTAELVRAYVAPQKLLAQSQGSVQLLPATDTVLVGWGHIPAYTEFDTITGTPLCDVHLCPLGFAALGWCKNYRTAKHHWVGSPSTLPSIAMRPDEQAVYVSWNGATEVRSWQLQIKADGNSDFVNHGSPVVKNDFESRLDVSSTAKMVRVAALDRSGQVLAYSEAVSTTETTVVAAMAAPPPKETLRGHLLRLALYISLGVAGGCVLAYLVLFRYRAATFAHVRRIVTSVVATVSRVLPSRRSYRYEALPTATPVMTEVVEMSMDGRSGGERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ39</accession>
    <name>A0ABR3YQ39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="16968" checksum="F1D76F76942D85E1" modified="2025-10-08" version="1">MADAQSTTFALPGGHSLRYKMTFPYAPESGRPTILLSGLLATTAAVWDDVVDVLHQNGFRTLRYGYETCIAALLSPQFDLRPVEVAGTVVSSDVERVLVVVGGKDADLPTSMKALADTMRDASGKDVGFHVLPNAGHASFIDGFDVWLEVVLPFLQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQJ6</accession>
    <name>A0ABR3YQJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_008149</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13292">
        <property type="entry name" value="PH_Osh1p_Osh2p_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="456"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="599"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="680"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="799"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="688"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1454" mass="156550" checksum="6420033448B5A633" modified="2025-10-08" version="1">MSEAGDSTHKRTKSAALSILRRKDRGTAASSVSGAGTGDEDVASEDGSVNAPLSHSNSGRDLPTMAYQQQNQSTTSTPVPIKGHVSRVSGTGASLTGRSPSSAYGASPARPGAVNTSAVPPHASASSPSSTLEQSVRKFRIVEALRSGDTAYITKAIRETSDPSGARASISSFATASAAGAAAGGLDDTTVLHLAIQCAEFAVVEYVLSDGAGLIDVNARDKDGNTALHLAAAQGRTQVVRLLLEQKEINDSLPNGQGRLPLDLARNPEIFQLLQLSRSLFTERKINEIQDLIARSEYRTLAQVLEEPRLKTVLDINSTEFASDPVTIQAGGTLLHEAARRKNSQLIQVLLLHGADPFRRDRKGKLPQDVTKDDVTRAMLKKSPAAVAAQRGIQEKAVLGAAAQGGLGYGSSLGVGASNPALGGGAGGTGAGSGSGAGSTAGSAGGPPDPLAGREAREMKGYLKKWTNYRKGYQLRWFVLEDGVLSYYKHQDDAGSACRGAINMRIARLNMSADEKTKFEIIGKSSVKYTLKANHEVEAKRWFWALNNSIQWTKDQAKEEERQRARSAELLRQAKADHTLQPQASHQSHLSLSQAASINNDGESVSASAAGGAGTHNGDPSRRNSTQLSRIQSAAQRSVSHKAAMVTAGGVGASTAGSIDDDTGTGLGANYFADAVEGKSRGANYDNGGDDDDLGDDDDLDNSSGRDRDAPSATRDALNITAQSARLQLETMAQVNQALIAEATRNPALTLTDTKTAAALSTYDAAIRSLTGLIGDLMRISRDRDAFWQYRLDREVEMRRMWEESMAQVAREQEALEARVGEAEEKKKTAKRILKEVINNGMLDDQPASSSASPHLGSSGILAGSTAAAAIAATSAMAADNATATTTVVGAENQDELVIPSSTGPKSPSIYTTNTSRRQTVLDQMATAGLSDSDDDDDDEFFDAVDAGEVVVESRLPSETNATTLGSNTNEKAATADETVDERGAIAKAEKDAGITGGGSGGEIVVSSGIDISQSFKGYENGIRSRLKIDADNRPKLSLWSILKSMVGKDMTKMTLPVTFNEPTSLLYRCGEDMEYVDLLDRAVERSDSIERLIYVAAFAASEYASTIGRVAKPFNPLLGETFEYVRPDKNYRFFIEQVSHHPPVGAAWAESPHWTYYGESAVKSKFYGKSFDINPLGTWFLKLRPKHGGKEDFFTWKKVTSSVIGIITGNPTVDNYGVMEIKNWTTGEIAYVDFKPRGWTAASAYVISGKIVDATGRVRVSLGGRWNSKMYARMTPGYQTTVTEPSGKSSGSADVSGDIDVATGQMRVHSSGPMVDPNRVFLIWQANERPKGIPFNLTPFVLTFNDINDQLRPWIAPTDSRLRPDQRAMEEGNYEFAATEKNRLENEQRSRRRDRETLGEEFVPAWFEKAKCPITGETYWQFNGKYWDMRDRAGQGDRSVWDQLEPIFVEQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQL0</accession>
    <name>A0ABR3YQL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="57814" checksum="D0DDAA97859AD4BC" modified="2025-10-08" version="1">MAVLQFATSNPAGLGITSIVALAAALTGIIYTLWKGIYNLYFHPLARFPGPFFARASPYPNVFNLIRGRIPFWIKACHDQHGPIVRVSPNELSFDNEAAWKDIYGSRPGHLNFHKDPVHVGSIESVPGVSTITMANDADHARQRRALSHAFSTKALMEQEHIIRSYIDVFSDKMKDFARKGTPVNLVAWLAYCTFDIIGDMALGEPFGCMDNEDFRFWVPLISASIKAGAFEQATRRVAQTGGTTQKLLLKLIPDRIRVTRRQHLQYSKEKILKRMEQTQSDHKDFLYYLIKQLENGSIGKDEVIVNGALMIIAGTETTAGFLAGLFNHLLRDQRVLDTLVREIRDNFESDKDLSFERLRQLPYLMAVIDEGLRIFPSAPIGFARTVPIGGDTVDGVFIPGGTTVSVPMWGATHSERNFKDPYKFLPERWLNKETSTDKFGASNPFSLGPRGCIGRNLSMMEMCLIIGKLLWNNDISMAGKQDAWEPARDYPGLHVYNNWMKPGLYAILTPRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRA8</accession>
    <name>A0ABR3YRA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide exchange factor lte1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LTE1</name>
        <name evidence="6" type="ORF">Sste5346_008128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="508"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1864"/>
            <end position="2111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="809"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1004"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1210"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1302"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1545"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1598"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1684"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="818"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1024"/>
            <end position="1039"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1210"/>
            <end position="1223"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1240"/>
            <end position="1275"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1620"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1713"/>
            <end position="1726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2115" mass="231890" checksum="8E292CC164975405" modified="2025-10-08" version="1">MEAAFELPIQSPTSERIVINRTTSAYPPLRPPSPPEAPSLSQLRVAHSRPSLSPKRLPGSSSARARLAAGKAVHGARDGEAAKPVTYSGGSLRELKLRRMTQPRESSDRPGARLTIGRPKKRTSPTNIPKSLLPATERKSQEENKIDRLSKKEATDGGDKWDIAPDGSSAGREGRQFTVANVGNNGRIYLRPTVRPAHLRSPQPNFVFPMTPPGTAGLDILMQDKDKRSDQQQHRPRQQQQQQQQPNKQQEQRHEIQRQPQPLRLEVTSNFYGSDWTPDQPSSPTALPVSRLRLFNANNAPRNVIPRPSTAGAVGGRPGGGHRRAISDSTIQDTSIARESDPGGFKIVITQPADDKLRAKTLEDLSPTHANGSAPHLEIAIPTWKIGSPRFTLRGSPLIRGSSYTPTEEPYSSRPSYFSPAFNHSHSLLEKEDSSVSPRQGIFERQKINGQGLSSPLGSPRSPRFRINEEGPRPTYHSNYAVVVPDMFDSLTFKPACDDRTIVRFSPATNAITAATPPRLVAEITSPKFMDYDLVSDFFLTYRAFLDARDLLRMLVARLRWAVERDDEAGMVVRVRTFVALRHWILNYFMDDFVIDYELRVLFCDLLNGFVNELSQDPRGRKVQLKILTELKKCWRRSCAQYWDGPDFDDSLGPDVPITPGGIAGHRNPTLDPTFWEEVAFGDVPDESEEDDDSNFLTHLQSPESMVNPEPGSSFHSTGGHAGHIDSVVLGDRPTTTENRETSNDFSARRQASPVSITSLDIVSCSFPTKNMKLLQASMGQPLGAHPVEPSLVYSSSGPIATTPRALVGKRVRPNDGQKASSQGQQHKRNNSLTDSLREHASTMDKLLQKNNEILMSLPYAGSLVRGAIFPPGQPYVEVLPPGTSGGVSRQTTLFQPFALDVPDSQKLKASAMSSQGMRKLLGSVRRALSTRGQTISPTQGNFINMAPIGPRGATTNRLPGTAIVPQARPRTNGFRPPVRIDLLGAKIAEDFKVAVREDASLDAAAQPGDDVPAEANDSPDAFGQQQQPDSKTAPSAYSDSLFLGWTPGGLDNLVRPISDTGITTGSKSIVIVDGTLPLEYPAMTGALALPNSNNGSVEMFGETFLSVAADPTPPTTPPGQPMGTPRRSSYVLGQQVLQPSLSMDPLPPFVPDMDTLGHSSTIGPPRPLIADTSIRPSSHVLQHEDSIILPQRPIDDIADEISSAVQEDITINKNPATNSFGLPSSPPIRRPQPSWIQGHSRHRSSRSHKSHKSHKSHKSHMSHMSHKSSRSYGRRRFASYASGTAPPTGILSFDASTYTDASTNEASEAQAPQPLRALRRRPGGDLRAVTTVADLDQGPIRRSRSVGSLTTYSESIRSSFIHSRPRESGGFVDVISVDFAARDKEDTFSVGMMTDKKLKKRMSMFSTHSSKPVMRPSFEAEAQKLAQIPDDVDDDGGVESALLKLEGKFERKSKTISFSESPFKMYTPLMAGKGTAAAPPLSGFLAPQPTSQDNNRLTAEEKIDHRHRQVVHSDLPPSHQSMLSKLGQHSTVAATELDAIESQYDGTETDEPRGSSLATSSHVHAFSPPPAFRPAAVPRMVEDVQSFLSESGESYSSIPLLDRGLTDDGRSKGAPTEEWANQSIFEEGNESSVQTPTGPSSGNNLAHQHSYEVVEKTESIEKIQHGDTMPQSPGQATDISFLEDESDHASDLSSELSVEFPDENEENGIYGPSNTGGPVRSNTVASRLPAHPLGDPQIEPAQTPPIPFQEQHPGKLVEDIDIHDGHPPSPPITLVQALMMSPDTAKIPELHDFQVWEDKPLPPTPSPDGTAPNTLRSKQAEEAEVLNAMGLRSVFEQPPAQVTAKAEAARTLSVHLPFILAFESEILAQQFTLIEKDALHEIDWKELIEMRWKNAENGNARSWVDFLRNSDARGVEVVIARFNIMVKWAISEVILTQDLEERARCTIKFIHIAAHCRRYRNYATMSQITIALTSNEVSRLTQTWAMIPPSDARTLRDLEALVSPTRNFYSLRAEMEAVGIDNADAGCIPFVGIYTHDLLFNAQRPSEIASSPTTAPLVNFERCRFAASIVKTLLRLVEASALYNFKPIEGITERCLWMSALSDDDIRKYSDALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRU1</accession>
    <name>A0ABR3YRU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PMC1</name>
        <name evidence="19" type="ORF">Sste5346_008168</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="601"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1144"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1181"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1222"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1258"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1455"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="326"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="424"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="1101"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="278"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="682"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1366"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1480"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="73"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1373"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1384"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1440"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1480"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1518"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1557"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1576"/>
            <end position="1590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1890652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1590" mass="171365" checksum="EAA2E4BFA5964726" modified="2025-10-08" version="1">MAQNREADAPLRRPRALADDSPTITIDTTAVSAPQDPPIMAEDGVPVYTNSPISVSDDATHSPVAVEPPSLSPPTNNNSLAPTHPPLGTGASSSRRGNSTSTNVSTSSTGRPQLQATTSFESRDSRPTSPHNVSSPVMSRNGDRTHGFLAVPHSHRSRQNSVDSEDGSRSVAISQGETVIGSSASGVHQPTRSMSMDGSNDAIMKDPDALKPDRGTEDAFKVDNNPFAFSPGQLGKMFDPKSLAAFYSLGGLAGVEKGLRSDRKAGLSVDETSLDGSVSFDDATTAKDNGKAVPGHGGAALGSEGQAASSAADGRSKGKDNGFFDRKRIYKDNRLPEKKAKSLLQLVWITFNDKILIMLSIAAVVSLAVGLYQTFGQEHDAEHPAVEWIEGVAIIVAILIVVIVGSLNDWQKERQFAKLNRKKTDRLVKVVRSGRLQELSIWEVLVGDVVHLETGDMIPVDGILIEGHNIKCDESQATGESDLIRKRPADEVYAAIENHENLKKMDPFIQSGARVMEGLGTFMVTATGVNSTYGKTMMSLQDDPEITPLQAKLNVIADYIAKLGGAAALLLFIVLFIEFLVRLPKQPSSVTPAEKGQDFLNIFIVVVTIIVVAVPEGLPLAVTLALSYATARMVKENNLVRQLKACEVMGNATTICSDKTGTLTQNRMRVVAGTVGSSQRFGEQGLADVDGDGSPTTPGSSAGVDNKNKDTDVASPSVANENREMTAQKMTSGLGKDVRDLLLKSITINSTAFEGEVQGKPDFIGSKTESALLTFAREHLGMGPVSEERANAPKTLQLIPFDSSRKCSGVVIELPNGRGARLLVKGASEILLAQCSQILRDPTKDIALTPLTDDNRDSLSALIENYASHSLRTISLVYRDFHQWPPAYARRNEGSADDVVFEDIFKNMGFIGLVGIKDPLRDGVREAVADCQRAGVVVRMVTGDNRLTAQAIARDCGILQENSEIMEGPVFRNLHKDEQLEVIPRLHVLARSSPEDKRVLVQRLKEMNETIAVTGDGTNDAPALKLADVGFSMGISGTEVAKEASAIILMDDNFASIVKALKWGRAVNDAVKRFLQFQLTVNVTAVVLTFVSAVSSEDESSVLTAVQLLWVNLIMDTLAALALATDPPQPSVLDRKPERKGASIISTTMWKMIIGQALYQLAITFLLYFGGKKVLPAREHATNAQVQTLVFNTFVWMQIFNQWNNRRLDNKFNIFEGLSQNWFFIGISAIMIGGQVLIIQVGGLAFNIASEGQSPTMWGYAVGLGFVSIPIGVLIRCIPDAWIESLVPGFVKRWYAGRQQKKREREREQEQVPDVTVSDPYTYDERFDYYPVALAEVRDELAWLKRLRGGRLNNLKFAIQHPRETFALDRSRSPSHSRSHSRSNSHSLPHSRSNSFNMSGGPVPQTPTREDSFGSTNGHGLAGGLGATLMTPTASPDSRRRSRSMRSMRSRSNSALGAPTVMAGIIAGSVAVGWSPIDRSNSSSSLHGQNNNSQNNNNGANNKTTSNKDFGGALPAGSGSSDAGRQASPSPAPNGFSQTPTRESSTARLLRDNTDGTEATSRTTTTDATAESSETAVERGRSTGSAPKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSE9</accession>
    <name>A0ABR3YSE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="356" mass="39716" checksum="B7CDCAA006E919A0" modified="2025-10-08" version="1">MAPNITSMFNRNSTNSLRNGSNNTNNTGNGNNTNNNAAPLNVDHYNTRIQILETRVRELNRQHDDQEEDIRRLKQAKADHQIRHAMRVSDLEHRLMVMKQQLWLATNPEAVAEAGASAPAPPLMHKPSVSMSSLFNETGGANSSSIRATLEAERTRRTELESQVASLRTQLNDERRRATTRDKDQRAEKAQLNDVIAARDATIATREAELRRVQAMLADQSTSSSQKTSRLERQVAEEAARRQQEKDAHTALVAEQTRAADDLRLQKNRESTARAAAERKMKLLQEEVARRGAQLEYYQQRLLRTAEFRLVKTPFDASEAGTPETVVASMAAPAEASQTVPESSTPTPMAPFEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTB1</accession>
    <name>A0ABR3YTB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007526</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. RimJ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF8">
        <property type="entry name" value="[RIBOSOMAL PROTEIN US5]-ALANINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="27"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="224" mass="24317" checksum="0AA0CD933F85AD0E" modified="2025-10-08" version="1">MADSTISDTVFPTTPIVQLERCVLRPYHISDLEPMCKAANDPLIVKYMRDAFPYPYDTDAGMTWLKICKAEGLPVEEKADEAKPAAPDSSPPAPSPEMNVAICLLDGTFIGSTGLRAMGPDGTDRYTREIGYWIGRDHWGKGLATEVASGLGRWALSPASGILTKDGQPLRRIEAGVYAENAASSKVLERAGYVREGVRRQAVIKNGVMQDVVIYGLVASDLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR0</accession>
    <name>A0ABR3YTR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cyp1</name>
        <name evidence="7" type="ORF">Sste5346_007491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="166" mass="18016" checksum="EED99FC331315B94" modified="2025-10-08" version="1">MATTVALDTSMGTVTVELYTEHAPRTCRNFVTLAERGYYDGTVFHRVIADFMVQGGDPTGTGRGGESIYGAKFDDEIAPPKSKLQLKHTGAGVLSMANAGPNTNGSQFFLTLAPTPWLDGKHTIFGRVQSGMGVLRRMGQVAVDAEDRPRETLQLKKARIIKAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTZ0</accession>
    <name>A0ABR3YTZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">High affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HGT1_5</name>
        <name evidence="9" type="ORF">Sste5346_007698</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="189" mass="20918" checksum="AC55FF1D6B874422" modified="2025-10-08" version="1">MFDSGNRLHIINGLCVHIWTQLSGNNAVLYYVTYIMEMAGLAGNVNLIASSIQYVVNVVFALPTILFLDRVGRRLALLFGSTFMMIWLYAIVGTMKTHGHSVPGGFEGSSVVTWTMDTDAPHAKSAVVAFTYLLVATYSFTWALISWCYPPELFPVRLRGKAVSLATSANWAFGFANSYYSPPGYEHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU86</accession>
    <name>A0ABR3YU86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007297</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024319">
        <property type="entry name" value="ATPase_expression_mit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12921">
        <property type="entry name" value="ATP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="729" mass="83673" checksum="FC8D1A805CFD0CA5" modified="2025-10-08" version="1">MATTSREHTPRLTTSDQRLDFVLQTLRAKDSNSLFNWLTNPVVALNHADGQKYVDEDQVQRERQSRTEVIARLPPVTFAEALRMLDPYVVSKNVDALADIAVSPSMAQLTPLGSAVNVYGTRIIYARLLHTLLYIWDLRTEALGASGNLLLNDFIVLLRAAGAASDMVRAKLIWKKMVPHGYTMMRHSQLYGEFLRARFLTERLYTQHDPVRMRVQAVNMHRQKKILHNSRLYHLERMRIRAERGVLHRFGQNINMPDRSEHLTRVLRSRKTLTKVYTKACISGQGHDERVQAAGIIALGRNSSLFMLQDLLLKRYGVKTRRIKGTRGHTVVGSRELPSESPLYPSATLLDAVVQTYCCNNMVPLALQTVTHFSQEYNIKIPDRTWYDLLNWAYALSSPRIDREFEIAGYPQRTTSRGMVKAIWGVMTSEPYNVKPGFEQYSIVIKSMLNNDSSILPALQLMRELKPHYQALLTKQVEAMQVVAETRQLRHRDRGAANYRLQRIIAEKWRVWFYFHSWCLRILKKSAHAEPGGELIARLIPKVIDEFRPFVHRYTWYATPTGMVTLREPHNHSKLVSEKIAFKMPTTRPSARFRNKDPAVLDEADPNGEPNPVDHFDPTFFSGSSVTNHGAIDKSDMQVAKAGPTTGQDEMEEYKVKIKVDIDNYAHDTVVDKAGNVLTPEQLRWYDRRFLPGTDLRRIVTRQRAKPNVLINSRGLPGRDRESLIREFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUR4</accession>
    <name>A0ABR3YUR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 1</fullName>
            <ecNumber evidence="7">3.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS1</name>
        <name evidence="7" type="ORF">Sste5346_007221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF220">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="37"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="610"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="538"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="550"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="697" mass="76967" checksum="DDA2D39D20B6C944" modified="2025-10-08" version="1">MSGTASLATPGGISDPALIQLVNKLQDVFVTINVNNPIDLPQIVVVGSQSSGKSSVLENIVGRDFLPRGSGIVTRRPLVLQLINRPAGSQQNGDAANGTTDKAANADEWGEFLHIPGQKFFDFNKIRDEISRETEAKVGRNAGISPAPINLRVYSPNVLNLTLVDLPGLTKVPVGDQPRDIERQIRDMVMKFISKPNAIVLAVTAANQDLANSDGLKLAREVDPEGQRTIGVLTKVDLMDEGTDVVDILAGRIIPLRLGYVPVVNRGQRDIDNKKPIQMSLEAEKNFFETHKAYRNKSSYCGTPYLARKLNLILLMHIKQTLPDIKARIAGSLQKYSAELESLGPSILGNNANVVLNIITEFTNEWRTVLDGNNTELSSTELSGGARISFVFHELYSNGVKAIDPFDQVKDVDIRTILYNSSGSSPALFVGTTAFELIVKQQIKRLEEPSLKCISLVYDELVRILTNSLSKSLFRRYPQLKEKIHAVVISFFKKAMEPTNKLVRDLVSMEACYINTGHPDFLNGHRAMAIVNERHNPAKPVQVDPKTGKPLPASATPARAASPTLEGDKESGFFGSFFAAKNKKKAAAMEAPPAMLKASGTLSERENVEVEVIKLLIQSYYNIVKRTMIDMVPKAIMLTLVQFTKDEMQRELLENMYRTDALDDLLKESDYTVRRRKECQQMVDALAKASEVVSQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVC2</accession>
    <name>A0ABR3YVC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="39733" checksum="4077289056D52BD0" modified="2025-10-08" version="1">MPSKIQYKFQEPVVLRLSDEERSTGIISEEHVASAITAMHRDGLVVLENAVDLEHVDKLNGLLSTEAEAMAKLPTTHFNDNSVDGKPTGNMSQGPPLDPTLMYEDVWANKPAATVLSSLLGPRPTVTYVNGNTALGGFNGARQRIHADLTFNHAQFPFAIVTNYYLIDVSPANGSTELWLGSHRDTTFRDHRNCTPTDNDDETEYDTSNDNTRDFGIRDECLEARRAWAPPIQPVVKRGSVVLRDLRLWHAGLSNPSSDPRIMLAFVHTPWWYKCPAKVVLPESAKPLVEEWASRQQDPIVYSAHFVPRDVDHKTVVFNPNFSSQNRGYLDMLPKGIGMGFIFYDVATGKEGEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVD8</accession>
    <name>A0ABR3YVD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protection of telomeres protein 1 ssDNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007237</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the telombin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032042">
        <property type="entry name" value="POT1PC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16686">
        <property type="entry name" value="POT1PC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Protection of telomeres protein 1 ssDNA-binding" evidence="9">
        <location>
            <begin position="140"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="596"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="596"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="639"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="734" mass="83232" checksum="F8B79F19C0F5F5B9" modified="2025-10-08" version="1">MVVQLTDKSLDTTEDTLSLHIFHPKAEEIPTFRLGDVIVAKGMRVQKAYNSQSFSLLSDYGTAIHIYRAQASSSNKLDRQQWLKHPESYGHKYSHPSSLAVEGAYAAYLHREINKDVLPSIQTFGDGLERSRFVRTKCHELKDVVDFQFYDLFVSVVTEPVHYADSGKTTFWVSDWSINEKFRDFHNEKHGRPGASRNAATDVGDEQGYLTKFGKQKQQQDDKSLAKDWPGPSGRRSMRIECYSPHAELVKEKVTRGSWIKLNNVHVKYFSHTGILEGFLHEDPQFPDVQRVFLYDTTDLERENADERYFAAMRRKKEYKKNVHAMSLKRKMPHDNSALEPSKPLNAKQRRKINRIEAGKTQDADAVVVAPKNRPNPYIHTEYPDRALLPLSHILGPSLFKAPGSNELQLPFANIKFKTQVRVVDFLPHRLVDFAVQRRICQFSILESDGSSSSSSDDDSDIYDSDDGGKVVWEWRFALCLEDASSATPNNNTDNNDTGKSPAPARVWAVIGNYEGQTLFGEDACDLRADKIACDLLREKMFLLWGNLEEIKRGEFRRKVLTTEAASIKTKEAARQREAAEAVARLAEKDLIRKEQEKRKKQERRQQEREQAAINGGNLRQYKQPDGGDSDDGDDADDANNSGSKSAQAQAPIPAMAPENAKRLSDIKKQLATPLLKLSSKPFVCCLQQYGIRNTVYDNGEDATDGQDEESDEPKQVWQPMLSMFGTKIRNSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXK5</accession>
    <name>A0ABR3YXK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045483575" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="1391"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="720"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="907"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1560" mass="152264" checksum="5C3ABE97C56B1F07" modified="2025-10-08" version="1">MRLSRPPIRRLAALAALVSSLPAASAWPAFPFFRPRDFATGDITGDIQTAVTTDEGPAPYAPAPTTAAETTNQVGGYAPAPTPATGTEDAETTGIEQVATNTDLTGTPTVLCSTYTIVTALVVTTVWTETIPVAYSCPASLTENTITLTGTGTGTGGGGITNTVLDFSSTETLTATMIAKRRRWGIPKLPLFKRDATDPAPEYESTSSSEEPQSTAVSSSSEQPQSMTISSSSESLFYSSSGGQVSPTPSGPVTSDGPSYYSEPPVYSDGPSFYSSEQPQSTTISSSSGPSFYSDGPSYYSEIPSFSSSGGQAISMPSSVVLSSPAPSSAFPSDGGSPVPSSVFPSDGGSPVTSSAEVTSPYYSSSGFVGPVPSSGGIASPVPSSSSFHFTNSSLPASSSTVASSSSVLSSSSSASAAGPSSASLPAGPITSSSSPAGTPSGPQSYSSPAGTPSGPQSSSSPAGPQTGSSPVGPQTSSTPLGPQESSTPLGPSTPSSVVGPQTSSIPLGPQESSTPLGPPFPSSLLSSLLSNHSSSTVIGPQMSSTPLGPSESSTPLGPPRPSSVGPQTSSTPIGPVTSSTGSPSTSNSSSSFTSISSLSLNTQILSSSISTQTTLTSYSTGYACESNSTTVLTSTFTTYASMVTSECITLIATTTPTTTSPNSPSTNQTPTAPSSSTVPVVSSSPTASSSPAESSQSVIGGTQPSTGPVISSTPVATSTPETVSTPQTGTTPQTSSTPQATTTPQVSSTPQATTTPQISSTPQISSTPQVSSTPPVSSTPQVSSTPQVSSTPQVSSTPQATTTPQTTSTPETTSTSQTQNTPQTTSTPKISSTPKDTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSPNPTTSRNPTTSPNTTPTTANTSPNTTPNTSPNTSPNTSPNTSPNTSPNTSPNTTPATSPNPTSAVSQASSAASQASQAASQASSAAAAGATNGDTGAASSAASAASAAASAASQAAADASSALSDAAASSPAAAASAASAAASAATVAASQASAASSAAAAAATSDPTAVAAAAAAAASDAAAAAAAADAAAAAANAAAANAAGGSAAGSNAGTNAGSTGGDAGGSAGSGSGTGSGSGTGSSSGSGTGSGSDSGSGSGSGSGSGSGSGSSSGSGSGSGSGSGSSSGSGSGSGSGSSSGSGGAATLSTAASLDDALLFAGCGNFLDFLKSDPDVWALYSSASVQTIFAVGDKYFNGTMPTSQTPAVSLRRRQLSPADVQRAQLAAGKQESDLARLRSIPGATISTNDAAADLHGSTQVIVSDYRRISSKSTLGRRDDNSSVSTNTSSTDALVTLYSGLGESVSLYNPDIYYKGGVIQVLDGFFTIPATLSQTDEILGYSQFANLVDTAGLTETLDNTSSITVFVPNNAAVQSAQLSGSLSASDIQNLVEDHVVVAANDTESVGYLPNLSDGQVLTTKNGKKLTITVDANNNYYVNGVLITTSNIVLTNGVAHVVDDMLVASASSAAGWSLQRGANTGMAVGVAVSTIFFSLVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYT0</accession>
    <name>A0ABR3YYT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="512" mass="57416" checksum="EE3437BAE8A81900" modified="2025-10-08" version="1">MAWLLAAVGVAALVAFVYYVISGIISYRRLGHIPGPRVAAWTDLWLVRGQLSGQLNFTLQDVNQKYGNLARIGRNWVVCGDPDELRRIWGVRSNYKRAYWYRGLRVDPYRDSTFSTLDDAEHDVLRAKLLPGYGGKDVDNLHDIIDAQVAGFVKLLEDKYLAVEGEGENEKNKGEKGTHKTVDLARKVQFFTLDVISALAFGKAFGYLDADFDKFGYIRTTESTVPILMSTAILPWIVDTLQSPYLRPFLPNVRGMVGIGTVMNLAREAVDARYGDHAVVKRDILGSFVAHGLGRDDAEGEAVVQIIAGSDTSATAIRSTLLYIITNPHVYTRLQREIDDGIRAGRISSPISDTEARNFPYLQAVIREGLRMWPPATGLLPKVSKADDTICGYHIPAGTSVAWAPWTVMRNKEIFGDDCELFRPERWMGISADHWRAMDQTVMLDFGGGSRYECLGKNIAMIELNKVYVELLRRFDIILVDPAHPWKSFNAAFFIQSDMNVRITMREEAVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A1</accession>
    <name>A0ABR3Z0A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="214" mass="22960" checksum="BE518BC1267795DC" modified="2025-10-08" version="1">MSQVLDLFSICGKTALITGANGGIGGAMAEALAEAGASIIVLQVPGDPNAAATKEALARVQPPVSFAAYDCDLADEAAILKTVAAIWDRDGREIDILVNCAGVSGHRPILDVDTAFREKVVRINMTANYVLTQEVGKRMIARTVCVRGTYILTPLTQGYFDNEPGFKEYILSRTPMGRWGEPKDFKGITVFFCSPASDYITGVRMPIDGGFHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0K5</accession>
    <name>A0ABR3Z0K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006205</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="65"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="557" mass="59636" checksum="4610C9E6CED8F0C1" modified="2025-10-08" version="1">MADISSNEPASEPAVHDSEKVGAVGRTDKVDNENDKNIDDLHPSNTSVASAELLLPIGDVDPVYAAKAHVLNHAIQSIGMGKYQWQLFAVVGFGWASDNLWPIVTSLIFTPITNEFQPSRPPLLTLAQNLGLLAGAVFWGFGCDIFGRRFAFNATLGLAAVWGLIAAGSPNFAAIGIFDAFWSFGVGGNLPVDSAIFLEFLPASHQYLLTVLSVDWALAQVVANLVAWPLLGNFTCQEDVAAAGNCTRGANMGWRYFVIAMGGLTLVMFGIRFLCFTIYESPKYLMGRGLDEEAVRVVHEVARRNGKTSELTLADLQACEPEGYINPAAASNNTRAVRSNATAAIRRKLAEVDADRIKALFVSRRLALSTGLIMTVWALIGLAYPLYNAFLPYIQATRGADFGDGSTYLTYRNSLIVAVLGVPGALLGGYLVELPRFGRKGTLALSTAVTGVFLYGSTTAVTSNALLGWNCAFSFSSSIMYAVLYSFTPELFPTPQRGTGNALAATCNRVFGIMAPIIAMFANLQTSAPVYTSGALFLAAGVLVLIMPFESRGKQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1C8</accession>
    <name>A0ABR3Z1C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SRB4</name>
        <name evidence="8" type="synonym">MED17</name>
        <name evidence="10" type="ORF">Sste5346_005915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="98"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="759"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="822"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="825"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="869" mass="94200" checksum="824CD11A7261D010" modified="2025-10-08" version="1">MADNRPRLAARPGAASGSTASGSSASEPLGPPPPPSSTSASASASASGPLFGTRDPVFRPWPLPSKQPTNIGEFVQRLKFQGVDFRDLSEEKLREQIKKEKAGEADDATAQAEKTAAAKKKAAEKSAKRDTSHDRPKGIQEMLAKRDEILFSLEAALQSGLIAVDFVSLLLSKDRPTQALQTLSPIVRDKAGIGTLSAGRVANAQQAVRALRGRFGEVHGLDETTKFNAQRLIEHKTECVGWQLLAMDRASEVLKFGRKRLRVEMRREERYWSEVLAVRDKGWNLSRMPGQRRVLRVKFGFSESAPDLRALSFAPLRRVKNGQVALDLSALGAPSAIVVTLRKKTGKGGRVKTGRSPLATRLADSASLEDCILEARNTVNAKELWRELNREARLMISHGVVFRDSEIVFPAGADTEGTITIEPLYHRSSTNVSVAEKKKREDEATHDPKLNDIAAGLCTSLQLFLAHGHRDHYRQRSSPQPLTDTVPLPPIYYMLRPIVANLKYEKAIQHISQYLADVCGILHGLGLDGSRFTLYERPLSMSIPSQNAAGQRPGQGGQPPQAVPSASEGLCNAFLAPREFSFEFTINPEVRILVRCRTTVVPLKAQYLIQLLPPVNSSPATAGSGPLAPPAPPPPRNPLLDTFPPADNYGTLRDVLDYVGRATTHVLASHARKLAKQWEDRSGMGAAWATSVDGMEIRQLNNAFWKVRFSLVPQSAVTVLDKLVSLTESGGGTTVKQEKTSAFTIENDEDDYVDESAQLVTKNGGGDDSAQDTENASNVDSPLARPSPPELRVYASWPMAESESAVYRKWAWGAASLEAAAQARTGGGGGSGGGGEDDDDDESESNDLESIVVGCVSGNLKPMVDTRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2H8</accession>
    <name>A0ABR3Z2H8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06152">
        <property type="entry name" value="YjgF_YER057c_UK114_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF39">
        <property type="entry name" value="2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="140" mass="15764" checksum="E8372F30A7527537" modified="2025-10-08" version="1">MSSLTYHNYDGYGKYAHDVFQYSQAVRIGDRIEISGQGGWDPKSAPPVLKPDVEHQIDQTFKNIDLTLKTAGGKGLSQVYSIRTYQPNLSKTPETFEILVKKVAEYFPDHKPIWTALGVESLAMPEMLIEIEAVAYDPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2U7</accession>
    <name>A0ABR3Z2U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PMA1_2</name>
        <name evidence="13" type="ORF">Sste5346_005807</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="698"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="765"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="831"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="865"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="76"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="927" mass="100303" checksum="7AC2AD93BFCCF4D4" modified="2025-10-08" version="1">MAESTSAAPALHTDIPAGNFDEKAGASAPAAAAPPVKPKVEEDEEDEDIDALIEDLESHDGHGADDDDDEEESNVHGGRVIPEDMLQTDTRIGLTEQEVVARRRKYGLNQMKEEKENLILKFFGYFVGPIQFVMEAAAVLAAGLEDWVDFGVIIALLLLNAAVGFVQEFQAGSIVDELKKTLALKAVVLRDGTLKEIEAPEVVPGDILQVEEGTIIPADGRIVTEDAFLQVDQSAITGESLAVDKHKSDQCYASSAVKRGEAFVVVTATGDNTFVGRAAALVNAASAGTGHFTEVLNGIGTVLLVLVIFTNLIVWVSSFYRSNPIVLILEYTLAITIIGVPVGLPAVVTTTMAVGAAYLARKKAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLSEPYTVAGVEPEDLMLTACLAASRKKKGIDAIDKAFLKSLKYYPRAKSVLSKYKVINFFPFDPVSKKVTAIVESPQGERITCVKGAPLFVLKTVEEDHPIPEEVDQAYKNKVAEFATRGFRSLGVARKRGEGAWEILGIMPCSDPPRHDTARTINEAKSLGLSIKMLTGDAVGIARETSRQLGLGTNVYNAERLGLGGGGDMPGSEVYDFVEAADGFAEVFPQHKYNVVEILQQRGYLVAMTGDGVNDAPSLKKADTGIAVEGASDAARSAADIVFLAPGLGAIIDALKTSRQIFHRMYAYVVYRIALSIHLEIYLGLWIAILNRSLNIELVVFIAIFADVATLAIAYDNAPFSKTPVKWNLPKLWGMSVLLGVVLAIGTWITVTTMYAHSPNGGIVQNFGNMDEVVFLEVSLTENWLIFITRANGPFWSSIPSWQLTGAILVVDLLATFFTLFGFFQHGQQTSIVAVVRIWIFSFGVFCIMGGVYYLLQDSVGFDNLMHGKSPKGNQKQRSLEDFVVSLQRVSTQHEKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z345</accession>
    <name>A0ABR3Z345_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RPC11</name>
        <name evidence="11" type="ORF">Sste5346_005482</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 9">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="111" mass="12540" checksum="4487C058F358DF52" modified="2025-10-08" version="1">MLLFCPCCANILTVSAHPETGRNRLECRTCPYEYAIATPLFSRREFARKEKEDVFGGPGAWDNAQKTKVQCPTEGCDGGEAAFFQVQIRSADEPMTSFFKCMTCGNRWREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3H1</accession>
    <name>A0ABR3Z3H1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 68</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS68</name>
        <name evidence="7" type="ORF">Sste5346_005323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0220 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007919">
        <property type="entry name" value="UPF0220"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13180">
        <property type="entry name" value="SMALL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05255">
        <property type="entry name" value="UPF0220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="180" mass="19310" checksum="3496945EE05F62E8" modified="2025-10-08" version="1">MSYDEDRLWKFQWPQWASSVWARNAGVYASGALFSLAFYVMLDAAVWSKSPYNGSDVHVTFVDWLPLMCSSLGMLIINSVEKARLASDSIGYSGIGMGGGGGGVAWQARVVLFLGFASLAGGMAGGVCIFVLKYIVPKVGMPMLGMGIENVVANGLVGLSSVILWVSQNMEDEYAYNLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4W7</accession>
    <name>A0ABR3Z4W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="170"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="37809" checksum="566C4A8E51E4FF93" modified="2025-10-08" version="1">MAHRHQGVLDFSDPAVVFGDAASRQHAEALFASLLARLEVDGDEPFVGVNMAAGMATIDIDDARSRLTDFAEFLNNNFFGPLKATAAKTPQPTPSSLSVPDLSRDQILPGSRSRIANLRRDCLIRDRHRCVISRHFDENEVFLRTNKHGDDAADDDGLRFVDTPDADEYDFLQVAHILPHSLMSIEGDDERSVARSNALAILEMLDAGVVHLIEGPNIDRPTNAITLTTRYHISFGTFRTFFEAVEGQPHTYRIQSVLTGRGRRPLQPVTRILFTSETIDPPHPRLLAIHAAICRILHLSGAGGYWDDILREAEGEMAKADGSTSLGVLTALRLGGWWDGVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6C2</accession>
    <name>A0ABR3Z6C2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nonsense-mediated mRNA decay factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in nonsense-mediated mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019458">
        <property type="entry name" value="Est1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF36">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10374">
        <property type="entry name" value="EST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomerase activating protein Est1-like N-terminal" evidence="4">
        <location>
            <begin position="88"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA-binding" evidence="3">
        <location>
            <begin position="209"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="983"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="829"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="849"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1225" mass="133491" checksum="34B76E1CE096ACFC" modified="2025-10-08" version="1">MATSSNSKMAAAPEASEAEQHWLEAKKITHSIVKKLEQIDKDESGSKKLLAELESVEHQLESLRLECMATTFTDFKFAHKNRVLDRLRHVHTLISTEYKKGLQRHRGHGQIVQFRTIEKQYAKHLKTAQYFYKGFIERLSARYRLRSLQRVAHTMQSGNLKMSDVIDADEAHLSHELTVACYRTVLHMGDIARYRLNASRQKGHNPDVAMTYYALAQDLMPQEGDAHHQMAVVLAEQRRDFEVVYHFLRSWSVQKPFALAFKNLTSEFKRLLQPPSNNRKQGNVPPDAHDLFGTWLVRLHANYFKGEEFSSQVELEREVLHRWEALLKKSEQPAYLQKAVLMNIAAYDIALKRVQNEWTEASSQSCQFILQFMVRTILVLSRVLESETERLFDEPPSEDEASVPVTPASAKKTTPTPSSNDKNEKNEKSERNERNPRANGRNRAGNNNTNNAKTAAAADNSVKPPVKKHSVSETCLSLFRVCVAWIATHNEDLVKFESHLAPYIADMHRAVTRCLTLFVELITKTEASPTTYLLPEDVEVIGLAPLDGWTALREGDANSPFKPHFDEEGVERKNTTYETMARIYDVVECTVRLIGDPAFPWVLHHVQEDGREVAKISYAEDRTSAPASSVPLMSIPASAPAVSASYAAASAATTSASPTPAIMRPAQSSGGSREPRQRKQRQPEVAAPAVPVPVQAPIQVQATPVVTVVPVSQPIINQPIGSPANINIASIAHQANPRPMSSPRLVSYKDMDDDDFLPGSMKEPRLMPIAAPVSTNQGPNTGPATADPELDLLESAAYSRVANFLSPPELHPHPPQQQQQQQATAPLKMSPSSPSYGMHSSTVDDAFGQLQTPSMPSVSTSLSPNAGTAKPIPSSPWGGSSYMHSLGYYPQQQQQVPQQAQQHQQMAYGMGNMDRPPTSIEDQLAYLTLVKQQERQMAAAAAAAAASAAAASSAAAAAAPIVPMQTSSSSYGMDSTRGFPSALSPVGAAKQQHHSPSNGGIPSGFANPWATTGGGGAINSHPSNSNGSRLLPQQLQQAQAASLGVGGAVGSMGSMGGMGFASPQAGSSPAMLYSSNFSMNNSMPSVQSSRALGGQGGGLYDNSYESIYSSASNNSYMQQQQQQAQQLQQLHSLQQQQQQQQAMATYAAVYGGGSAGASGAMGSPSSHAMWQDAATAWSRNPLGKDDPTHFRNTMRQSGRMEDTNTYDRNALLSALDDTGSPGQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6E6</accession>
    <name>A0ABR3Z6E6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_005120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF24">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="47"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="542" mass="60424" checksum="4ADD231111BC1D13" modified="2025-10-08" version="1">MAEPESKTALTRLAELDEFDGLTLADVTPPLEKWWFQYPHLLKLNLLLLCGFLAQFTCGFDGSMINGMQSLPEWIEFFGNPKGAALGQLVNAINFGVIASVLVSSQLCEWFGRRRPISVGTFLVVFGSALQGGATTYGMFFAGRFVVGIGTGITAVAAPQIMMECAYPLHRGKIVSLYMTQWVVGYLVAAWTTYGTFQMVGSVWSWRLPSLIQAAPALLQFVLSWFVPESPRWLVYKDRVDEAVRVLAKYHTPDNDTSSRLVRFEMLEIQTTLEAEKIQKASSWKEFFATKGTRKRLSILLFIGYAVQISGLGLTGYYLTKILESIGINDAKTQLLINAYHSLFQLACSITFALLIDRFGRRGLITSGMTTMLVVFVVWTICSALNQERNFEDKSLALAVVAMVFLFQVGYQQLAVASVPYVVETSLFSLRAKTAMIFQFCGYSASLYNGYVNPIALENIGWRYYIFAVAILAVETVFAWWFLPETKGRGLEEIGEVFEDGELVTGAEAIHQQRSAYQENVMETTATKTEASPEVFHGEAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z824</accession>
    <name>A0ABR3Z824_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="631" mass="66652" checksum="1D3754D9461450ED" modified="2025-10-08" version="1">MLVPPAPTVAVTLATAATLTRPPHPPVTTAFASRMLELRQDMTGTDMLSYDLACIDYIDALSCDSAYVSCLDSVESVFYGTDFTATTNDNNAYTQLDNGISSCYCNYGVAYLSCYYGALENKACVSYLGVYDWTSYESYWYIDNCGTVPPTLFGGGGAGKTTKETKPPSTVSLDLQSVHVVTAKSQPPLPDLTYSPLYQSTASGNLLQDECASTQFTLIEDISTVYWAAYVGCASNQPQCCPWTAASEFFPATVTGNTTVTVTSTVTATGADATGTNIGLNAFPVAANKDQGVLKRCASDYYSISGNCCPSNYWPFTRDLGGQTPCYSSLNMVTEAPTLTAGLIGEPTNTEKPTSAVVNVVWAMSYPVESKSSLSKGAIAGISVAAVVIVAAIAALSFFLFRARRKNKVLQQQVPQQQQAAAPPPQEGQVLAAAPLAYDPNKPQGMVQVQPAAGGYVYPQQVYPQQGYAQQVQSGYVDNRASLAPSSATPISQLAPQSTGTTNVSELSTQGLVGGAPTPAPAPIAEADESAVIYHQQLQQQQQQQQYYQQYYQAQGQIPGQVAVAPQPGYVSAQPVYGQPPPQPQPQQAVFYEASDGGQPAPVAPVEVASPDTGVSPLTANTAHPPGHQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z832</accession>
    <name>A0ABR3Z832_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701:SF1">
        <property type="entry name" value="UP-REGULATED DURING SEPTATION PROTEIN 1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="793"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="813"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="908"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="940" mass="97424" checksum="B490307E809DEDC8" modified="2025-10-08" version="1">MGYDKDTPRKPTLASRPFTRAPLTPKIAASSTPSRTPTLSSNNSYSSNNNSTSPYQTVTVSTPLARRVTGLSSTSNSSSSHYHSGNNDTTSPAPSSGAGVPSYLNNVTPRSGARQSRVDGGSTTPTGTPNGQGYGLGIGVTGNNNSASSDPDSKFFYASEAKSSVSVAPSASAAAHASHSTPTPTLAMAGHSSSSLAATPSGRPASTFFYANGKSLPPANGHSPASASTSAFPAHIPPPMVSPTLSSTPAASKFVHANGAALERKLSSSSSTRRAPATPTMAQQQQHQQHQASASSRPLSPVKMAAVSPYPLQKSMSFPVVPSTSSGSSSVNGSTYNANSSTGHRPSIPGNLSLNAAATAVGTQPLVASPGPVSPGSGRLDVISRQRSNFSASIGSIGSNSSAGGGGGHSRKGSLTIADPPTVARLLHSSQPNSEVPSPASGQFPAYPFPSVSSPGASSNGTNNAASSGLAAILQAADDLAEDDEGSEADHNEDGEGSHGDDDHTGGKDSRRSSTNVSASGAGHTHSQVDELVTMARRERKVQDLEITNASLEAINRSLERQLRKQKNELRQFRRLSRSGRLSLAPSTAPGGSVGGGSRITSSSTVEGPIQDMDQLLGEDDSFLEEFDDEYGSDMEVSYNEDEDDDSSSSYSEGDTRRKRDERRLQLDLAQHRQLLVDSQKINQSIKRCMNWTEALIQEGQKALAFQVRVSEVQLGGRVLAADEVEEREQRERDAKANDASERSALLLKESELLLEDDDHFDDQSELNVAHDIESVAALKVDGAVEASVVAADATSADASTSSTANTPASSSTDDHDQANRDEAFSPISHNIRTVRFDTGDGDEKADAPVKVDVPSLDNIATASVPEAGQVEAASELDTMPDTPSKPPPAPVVEDAAPILRSPPEPAPAQDVVAAPPDVAATLTETPPTAVPAEVATATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z864</accession>
    <name>A0ABR3Z864_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ribosomal small subunit component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RSM19</name>
        <name evidence="5" type="ORF">Sste5346_004396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="90" mass="10301" checksum="AFA0A29767B451AC" modified="2025-10-08" version="1">MLPTQALFKRSVWKGPHIVPIAFPKIIPGKYTPPIRTQARAATILPNFIGLKFQVYNGKVYHEVTITEDMVGHKLGEFSPTRKPFIWGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z938</accession>
    <name>A0ABR3Z938_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="258"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="477" mass="55190" checksum="06E763219D91BE1B" modified="2025-10-08" version="1">MSGLQNGAAPARALDDDSDVEEEALVADYREQVEYEDGLEELEQVNSLTLAQQNDDIQSRLAAAAQPLDFSAPLEVKFQSYDAYCSLFHFILNSEGPVDLEPPSYYWAWDVIDEFIYQFNSFSSYRMRIARQNNNEEEIAVLRENPNTWGCYSVLNVLYSLIQRSQITEQLAAQKRNEDPAAVAGEYGSKNLYRMLGYFSIIGLLRVHCLLGDFSLALKTMDDIELNKKAMFARVMAAHFTTYYYIGFSYMMMRRYSDAIRMFSHILVYVSRTKNFQKNAQYDSITKKNDQMYALIAICVAFSPTRLDDAIHTQIREKYGEQLLKLQRGGPESLPIFEELFRAACPKFISPVPPDFENPEANVDPIEHHLAVFMDEVKNNMWSPTVKSYLRLYTTMDLKKLAGFLEVRPEELRSWLIVNKERTKQLRWNDQKLLDGEWVNVSDLDYAMQGDLIHVSEAKVGRKLVDWYLRNLSRTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z982</accession>
    <name>A0ABR3Z982_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_004768</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15413">
        <property type="entry name" value="PH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="300"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="523"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="609"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1151"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="527"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="617"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="679"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="697"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="760"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="871"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="919"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="938"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="965"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="996"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1027"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1081"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1100"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1121"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1162"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1193"/>
            <end position="1202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1202" mass="129618" checksum="268D910941A8DF98" modified="2025-10-08" version="1">MASFTTFLIVYLFGGVTFLPLLFVAVIYAWTRPVEPDTQADLDTILPDGNRVPKGKDNYKYDGLVLPGDDIKTLEAARKEHAQERSDFGSSKKHHKHRQDPADDGATAGYFAVHRKYVAMGGNLRPIERGSSVGSAEVAPPSPSVYQTFFRSMLNKKSDPNKVEVSNAASPRPKNAHNMFYVVLRHGHLILFDDDQQVDVRHVIKLADHDVGIYSGADVVPEGELFIKRNAIHLSPKNHERAKAHNAPAPQPWFFYCENCSEKEDFYFSLLRSLDKAPKPHEIDVKHLTSLMERLHASEEAAEMRWLNALLGRLFLGVYKTSDVLKFIESKIITKLSRTPRPSFIASLVVQRVDIGETTPQITSPRLKSLTAEGECIVEADVRYTGRFEIDLAATLRVSTPIGQQEVKTSLAVVLTQLEGHMLFKIKGPPSNRIWFSFRHMPKIEMETRPIVMARQLTWPVFIQIIEGKIKDAISESIVLPFWDDTPFFPTEKKAYRGGIWEDATDAEHEGTAIRTEAAGGVPVETSAGTSPAIGTNLATGTDAKSASSTGVAINTPENEGNVSPAVLRLRRLSKTHSAPTSGAASPTAMAAATAAAGESANAAAAKAINNRKSRTNGDGSDASSVGMSPPKRFSRTTSALASPSEPTVGTDRSHAEASIQSSSPPKNGKPNTAMSWLSSGTLRSRKSSVSSMDSSTPGQVASNRVNRSRSGTKDEEDEGGDNMFPVNDLETPVGRSKTVPVDAADSSETGSLDGRSIKSRSGGASSSSLAGMAGSGSNSRPPLVRKPSIEPSFTTTITSDSGGTPPAKRSTQLAAAMTGAAQSAKRWGINALQRRAAAAADRKARTGLENRTTSSGEPLDLSKPMGGGMPLPPPGEPLPMPSELALAKDGTSSSSAPSSTPPPQLPARITPIKRRPTTESTFRSNQSQSQMHIPSMQHEHQHNIKRKEVYPQVPHRKPVHQEDSSNSENNNSSPRPPQHRRGQSTTFDEILGLPPSQNSLANSGSQAQYSSHYDEQENMMVVEAPIDSESDEDEMDAPQLPNCDGSTSHKAVPAGEPHHSPSDESGELLIDAPREEADSLNGSEGVSDSQSGYVHEQSALPSTQIDATNTYESSGRESPALEDDEQDGDGDHDDAQWGTLAESVISAFLEGEDGQTTAEHGATENAEHVEHDEHYEHGKVGVDEAEVPTSSLEKERESIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z995</accession>
    <name>A0ABR3Z995_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004784</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04043">
        <property type="entry name" value="C2_Munc13_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052811">
        <property type="entry name" value="Glucose_resp_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010439">
        <property type="entry name" value="MUN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014770">
        <property type="entry name" value="Munc13_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263">
        <property type="entry name" value="ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263:SF1">
        <property type="entry name" value="C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06292">
        <property type="entry name" value="MUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51258">
        <property type="entry name" value="MHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD1" evidence="3">
        <location>
            <begin position="736"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="944"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="domain" description="MHD2" evidence="4">
        <location>
            <begin position="1154"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1429" mass="162030" checksum="CFE2C1A50FA1B5EF" modified="2025-10-08" version="1">MSTASNRTSRPSRSSLHNSRMSTMSARRPRAGSRAAHLAEVQFEEGYSYALRIAYLNYLLQPKKKRKEYVVAPKPVRTHTASNSVGELMKEFMPSGSSSSSSQANMKLPHSLRQALEKRMEGVLRGTEKLPGYNDAAVKRTFGEAYTAFTADSFRKSIDKDRKIEPLILIFYTSASKAQGRGKAADDDSWKPLVDRHVALFVRLVSSLMRDLGSDQGRPEFMGRLATLEKKLLTNDQDLSLDTNQPGEHKTIEVEIPLTYDVKDMPMVQTVARIFGRTQSEVQTDIDRDLTVWTEEAALKDLKTYQHQLTSNMPGALRRGDFDLDSAYDEWKKAEIHQLAQMMLDLLTVRPDLAKSSTGGAGAASLGGNGGDKPLPIRPTSMYGEDQTYADISRMISSHPDPVAAASVVNQFGYDGSMGFSSLSMDDSTNGSSSIRAVEEAPEYTYIPADPRSYYKFVLKHAMSYDQLHHDEGTIVSEAVPLHRSSMDFLIELAVHWRIPQFSREVLLLDVASQKYLDLEMRAEEVYEVFEDVKDSATFDHLPHNKKPPYIQMFGQPLHSIERSHWASHDYAAYQQILVKMQEAMLRELLEVASQCYEPKPQSIGPTLMFIENHIHSDDAFPQRPETIAQFAEALTATMRDRAAGLYREFLDTNIPREEDDWDFSHVVNLGKAVVAVCDRTRKRYRKNPEIMGVSPFKELVGTMFPSFEADAKAIIERIVQKAKDRGLEVNMQDGFDLYKELADIRKIHVESLPGKPFAFHIEGLLEEFVWRWIKGAQERMENIVEEAIKQDQFQVRVQNPGDVPTDDERHSVSIIDTFQAFNQSVDQIYQLEWDDDVHHAKFMTALAKAFTAGIGRYCEIVEQRFAKEMDRPSAQELADANKTTQERWMQYAKDALSNKDKVEPFQFYAESFVKLNNIEYGMQALDALEKAVNVDGCAEVLKRENGPVKPVDRRNAKYVFTIKIVEAEDLKACDPTGTSDPYVVLGDEYQKRLAKTRIIMRNLNPRWDESVEITVSGPLNIIATIWDYDTFGDHDFVGRTSLKLDPLHFSDYLPREFWLDLDTQGRLLLRVSMEGERDDIQFHFGKAFRHLKRTERDMVRKVTDKLVAHINASLSYEALKSLLNRGSTLASMAALWQKRTSTKVQPLTQTDVENTLQPLFTYFNENFAIMNQTLTHATMMAVMTRLWKEALMAIEALLVPPLSEKPSTQKPLTQAELDVVYKWLEMLFDFFHARNEQGEVLGVPADILKSPKYHELASLNFFYFETTENLVRTSERMAAATAQRAQQQLQQQQSQLPANGIIPGLAAGRHLSAPPGFGPGAAGGGAFASMGTIRRGKSIMMARNLGTMRRAKEEKRKDAQADPSDDMILRILRMRPEATMYLKERHRQKERMQAHQAAAMIVRQSISQGWTGPAFGGAMYSRNNLPMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA40</accession>
    <name>A0ABR3ZA40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-T/Histone H4 histone fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22920">
        <property type="entry name" value="HFD_CENP-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF5">
        <property type="entry name" value="CENP-T_HISTONE H4 HISTONE FOLD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="6">
        <location>
            <begin position="475"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="383"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="581"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="617" mass="66329" checksum="DF5DF5443F071E84" modified="2025-10-08" version="1">MSSPMGTSTARGGAAGSAVQTPTTGRQQRQHSNNGPSSVGPASAGGNYRTPNTATKTNFGRRTPGTAGRTPHARAARLALDSRRTAIFTPGGRQSRRKSGRMLRDSPRDLLRNLSRRLAPISQPIASSSSPGSGGSAQQSRRHRQPLDIDMEMDDMMHGGPDSSTASATRRRTIRSVLGIDDDDDDSLLLDRPRMSLNIEDNDNDDDLRPHRSLILENGESDDAEADADADLANFTQRSIELARRAATQEQLLQARRFSRASLGVRSSFGSMRMSDYMDEFGRGADGGGEDNDIAGRLEQTSAFFPEGAFDNLMPGESPPGANMTFERVDSDTGEQHEARLGADGRESGFGVGVLDLGLDGGNETTFMLGQRSPDRTLGTLLVEGDGENEPGLLGGDDAGEHDFGANFDNFDDYGGGDDNGGGNFWDDDDDEPNNEHDAERVAASAHDGAQKAAGVIQASQEKTKPGKRLKLSAHGIAYPSLPVGVVKRVAQTFAQSSGSGKAKLSPETVAALSTASDWFFEQIGVDLQRYAKHGGRKTIDESDVLLLMRRQRQVNAAVTPFSLAQRMLPRELLQELRMIPDAPTLKRQRQNKQSKPAQRLSSGAGRIGKKRANDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG4</accession>
    <name>A0ABR3ZAG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Iron-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ISU1_1</name>
        <name evidence="1" type="ORF">Sste5346_004050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="80" mass="8699" checksum="87090FB0590F49CE" modified="2025-10-08" version="1">MFTARTALTRSLAAASTVAASASTRAALRAAATRPSLAAAPAATVPSARRFYHEKDKCLRTAILRPRFSLHQIWCTQRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK7</accession>
    <name>A0ABR3ZAK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="250"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="356" mass="37797" checksum="32098A0166332B6E" modified="2025-10-08" version="1">MAQLKAMDALEPFVALSKSANSPRQVADLVVRATSHPSTYFFAELLQTPQIQALASADPEYAPYLTVLQIFSYGTYADYERGTAPSPSTKSTQSSQPQSQAAPPTSTSPLPPLTDVQATKLRHLSLISLATDRASLGYDHLVRELRLEDARQLETLVMAAVYAGLVTGTLDPAHQVVRISAVAPIRDPTPDAIPKLHSALSNWSQRCETTLAGLDAQIAGIRRTAAARAEETQKWDSQFKRAVETERRAMLNKDNSGSAAGSAGGEELGGAGGGAVWSHGKRQMTLNVSSGGKGIGNPRFNKRGSNLMASSSSAAPSSQSVPGPQGTPRFADDHGATDAMDLDDDEADGNKRNRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL1</accession>
    <name>A0ABR3ZAL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methylitaconate delta2-delta3-isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003999</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709">
        <property type="entry name" value="ACONITATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709:SF2">
        <property type="entry name" value="DUF453 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="16"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="47489" checksum="86601EFB6A193809" modified="2025-10-08" version="1">MADRIAQRLLTRLRSQGRVAASPLRSNARSSSSSSRPRPQERNFPAYFVRGGTSNGLVIREEVLPKFEVNGGTPSTAEVMKARAAAWTPVLVPAMGSPDPNHGRQLDGMGSGVSSTSKICVIAPPANDAERTYRDVNFTFVQVGIRDGRLDLAGNCGNMISSVGPLAFDLGYGGTTMTAEDGSQEGLVRIFNTNTNKLIRSRFRVAGNPPRFFPDGDYAIDGVPGTHSRITMSFVKPAGAKTGAQNGLPTGHAVDLLSRRPGEEPFIPASLVDVSNPGVFVLGSSLGLANDKDAVLKDVATAIETDRELKATVDHLRREGASRMGMDPDTESVPKIVILFPPSTEAGEAKTDIRCVALSMGQVHKAVPLTLALCLGAAARIPGTLAEQLVAEAQQNSTSASEKGSGTIVIGHPSGRVDVGTTLDETDGTVLSAELHRTARVMMEGRVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAM0</accession>
    <name>A0ABR3ZAM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="50243" checksum="B4E931288F7E2D51" modified="2025-10-08" version="1">MAPGRRASMRSVRTLPIVHEDDDMIVATTPELAAAYPVRQKRHSGVVTQLPPLPAGEVGEATESGSGSASDDDTPSPPSPSRTPQRNPNPRRYSGGSIHSHRSQGSQGSLGSRQSYHSQPQHIGPIPSSGYGLNYPYVNPACSESSEESGITDRKLEEQAGAAGVGAGGRGLPKRSQNREWFSKRGGWWRLILTLLLLAVIAVGLGVGLKFGLQQANNNSSSSSNGDNNGNGSGSGGDVPSTPATPSDQFPAGSYSFTVALTNVSTACTTNGFAFGCAPGANNVFSSSASPTAQNASAVTFEWIIEGTTSGSTSSASTLTTYTISSHSSSPFPFSNIHMTLLDSGLSSERLVFNLSMDLAYIPTNDLVDHQTSAATCYFNQTTTQATLWTKQRATFPSSITAIQAPVNASSTFSAWPFAVELSEVQQAGPAIPDCVDYHGNSLGDFSIPDGGGDAADVCGCWYSNMVSGSSGSSGSKNGTSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAR6</accession>
    <name>A0ABR3ZAR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22849">
        <property type="entry name" value="NuzM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016813">
        <property type="entry name" value="NADH_Ub_cplx-1_21kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022976">
        <property type="entry name" value="NADH_Oxi_21kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="20418" checksum="D56C5900B7C32FC8" modified="2025-10-08" version="1">MASKAAAKAVTSASHVVSISQKQTLQSKGIWEGFRRLMAIDKNRSNGVPLNPYYRTPVPGQQDPLQITDPVTLPAGDIAGNPYWKRDARRNYPRLSTVTQADAVALLSVGSAAAPKAELIGEAGSKALVAATETGKTEGLGTFLAKSNATATPAVADFFVDGLPPLPSGQSLNSGAWDVHKYELVPEQTYPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBX4</accession>
    <name>A0ABR3ZBX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="97" mass="9773" checksum="A72030FAA2B6E2DF" modified="2025-10-08" version="1">MSSSKAMSSTAEAPYVAQAGAGMAGGAMRQMGGPGLPVPMPNLSGQPNGLVGNLLKGPIDANGKLKDAALMVGIKLDLEAEVHLTARVRGDILVGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD30</accession>
    <name>A0ABR3ZD30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyl transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003628</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="340"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="44122" checksum="88D75A8AF3B6B255" modified="2025-10-08" version="1">MLSAVPLPRRLRSRLGLVVTGVLIVIALLSRHILYTAWTLAYLPFIWSRDSPSFVISQALDNFDITFADYNASQTEAGFGYPDRVPPVMHHVVLGSRPPLPAWGETRQSCLDLHQGWETYYWTDETAAAFVAEKFPEVKPTWDSYPFLIQKVDALRYMVLYEYGGAVLDMDLRCKRALGPLRRFGFVAIEAVPVGFSSGFMMAERHNPLVGAIVDSLKEYNRRWLGLPYPTVMFSTGCHFASTIHTLQANRSDYKVLRGPDDNRDMHKLNGKVSTPIFDHLGSSAWHSFDGAAIIMLRNALPYMLPVILVVGVASILIAKRRRLWLLRRPVPHMRDLLRHQQDEHQHDKYVSGSESSSNSGDDSDDEKAFRDLSPRTASREYLSDGSSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD72</accession>
    <name>A0ABR3ZD72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02972">
        <property type="entry name" value="DsbA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="23896" checksum="1A2DC42D9C4E0317" modified="2025-10-08" version="1">MALAPKFAAHRLVFGDLSAAAASVAPVHTVEIFLDYVCPFSAKLFNTFYTGVVPALRSKPVGSRVQVLFRHQVQPWHPSSTLVHEAGLAVQRAAVAAGKPLLFWDFSAALFKDQKAYMDVNVQNEGRNQTYKRLAALAASSSGGAIDADAIYKDLAIAAEPAADGSVNTGNAITNDLKLVIEAGRLVGVHVSPTVLFDGLVNNDISSSWTAEQWLEYLEKNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK9</accession>
    <name>A0ABR3ZDK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="7">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GPH1</name>
        <name evidence="9" type="ORF">Sste5346_003171</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04300">
        <property type="entry name" value="GT35_Glycogen_Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF3">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE, LIVER FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 7 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="895" mass="101451" checksum="B1CEAFA3CDDD1D57" modified="2025-10-08" version="1">MSSEQQLPTRQRRPSATAPIVDIQGSVGPAGVTRPKHRRTFTGFGAQEIKGVEASIPEHMREAWLKHQASGFQNKEQFEKEVVRHVETTLARSMFNCDETAAYAATSLAFRDRLIIEWNRTQQRQTFADSKRVYYLSLEFLMGRALDNAMLNIGEKEVAQNGLSELGFRVEDIISQEHDAALGNGGLGRLAACFLDSLASLNYPAWGYGLRYRYGIFKQEIIDGYQVEVPDYWLDFNPWEFPRHDVTVDIQFYGNVSKTTDESGKVTAHWQGGELVRAVAYDVPIPGYATPSTNNLRLWSSQASGGEFDFQKFNNGDYESSVADQQRAETISAVLYPNDNLDRGKELRLKQQYFWVAASLYDIVRRFKKTKRAWREFPDQVAIQLNDTHPTLAIVELQRILIDLEGLDWDDAWNIVQQTFGYTNHTVLPEALEKWSVGLFQHLLPRHLQIIYDINLFFLQMVERNFPKDRDMLSRVSIIEESQPKMVRMAYLAIVGSHKVNGVAELHSDLIRTTIFKDFVTIFGPDKFVNVTNGITPRRWLHQANPKLSALIATKTGGPEHFLKDLTLLNKIELSVNDPAFRKEWAAIKLANKQRLADYIKTTTGVVVSPQALFDVQVKRIHEYKRQQMNIFGVIHRYLVLKSMTPEQRKKVLPRVSIFGGKAAPGYWMAKQIIHLINSVGSVVNNDPEIGDALKVIFLEDYNVSKAEIIIPASDISEHISTAGTEASGTSNMKFVLNGGLIIGTCDGANIEITREIGEENIFLFGNLAEDVDDLRHHHTYGQDHKIDPSLDKVFQAIQSGTFGNADDFNGMVAAVREHGDFYLVSDDFHSYLETQELVDKSYADQELWVTKCITSVARMGFFSSDRCINEYAEEIWNVEPLKPETNSGVPKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDW0</accession>
    <name>A0ABR3ZDW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846:SF11">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="44"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="196" mass="21387" checksum="613B1CFA5197A091" modified="2025-10-08" version="1">MRLPYMPNPPKFAESAYNAIVERVAARRAPRPLQPLDLALLHSPPVADGWNSFLGAIRTKTDSIPADLRELAVSRVAAVNRAWYEWGHHAPLATAAGVPDAGLKVVLEETPYKLDDTKAVDSGVLTAKQWAVLVYTDEMTRTVEVSDGTFAHLRTLFEEKQIVELTAVIAAYNCVSRFLVALDVGERNGTGPDAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE40</accession>
    <name>A0ABR3ZE40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="45581" checksum="746A7414F8946DFB" modified="2025-10-08" version="1">MAQEKLLPAQMDTVQTLGKRICILADGHVYLWQFGGMLREVDMTGLDEKYLQPDVDGRLPSYFILDPVNEDVFYLGNFELDVGQMGRNGKLGFHLHMFDGLRYKETFSDYIHFDNYAFPLCLIEATVRRDARGLYSLASWRAGSGAPGPTRSVSPTEVVGVASLAFNIYTKTFSLSFWNLPPATPAYGRESSQLIRIHIWNDQLITIVDRYRDAPQGKVRRAKPLLFAFDDEYSEAARCSAARPFSEVPLYTSKLDDEDSTENEDNNNNNFPSPPSDTHIKPELRQKVRFDELTPNSPGQWLQDDDDWTKNKCLLRFALDVDSSPSRADPYRPAHIGSYFMQGDDDFFVFRHGNEYTIWSFRDDIVHSVECPVVGAGGIVDAVGAVSLSGEAVGEAGAASSTIPGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEI6</accession>
    <name>A0ABR3ZEI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PRE9</name>
        <name evidence="7" type="ORF">Sste5346_003373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="251" mass="27902" checksum="E7DD6F8AE97F0F6A" modified="2025-10-08" version="1">MSRRYDSRTTIFSPEGRLYQVEYALEAISHAGTAIGILAKDGIVLAAERKVTSKLLEQDTSAEKLYILNDNMICAVAGMTADANILINYARQSAQRYLLTYNTDIPCEQLVRRLCDLKQGYTQHGGLRPFGVSFIYAGWDPQRQFQLYLSNPSGNYGGWKATSAGANNASAQSLLKQDYKEDCTLKEACGMAVKVLSKTMDSTKLSSEKIEFATVGQTKDGKIYHRLWSADEITALLKEHDLAKEESTDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEK5</accession>
    <name>A0ABR3ZEK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_003025</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="13">
        <location>
            <begin position="349"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="15">
        <location>
            <begin position="622"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="829"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="850"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR003354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1224" mass="136396" checksum="3162CBE63F19A065" modified="2025-10-08" version="1">MATPSQMLTKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRAVAFHKTQPLFASGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTVFFHDELPWIVSCSDDQTIRIWNWQNRSLICTMTGHNHYVMCAQFHPKDDLVVSASLDQSVRVWDISGLRKKHSAPTSMSFEDQMARQNQNQADMFGNTDAVVKFVLEGHDRGVNWVAFHPTMPLIVSAGDDRLVKLWRMSETKAWEVDTCRGHFQNASGCLFHPHQDLILSAGEDKTIRVWDLNKRTAVQTFKRENDRFWVIAAHPEINLFAAGHDNGVMVFKLERERPASAVYLNNLFYINKEKQVRSYDFQKNLESPTLLSLKKVGPAWVPPRTLSYNPAERSILVTSAADGGSYDLINLPKDGSGAVEPTELKRGSGNSAIFVARNRFAVLNTATQTIDIKDLTNNVTRSFKPPAGTTDIYFGGPGNLLIITPTAVHLYDIQHKKTIASLNVNGVKYVAWSNDSLYAALLSKHNVTIVTKTLEQVSTLHETIRIKSATWDDAGILLYSTLNHIKYTLLNGDNGIVRTLDQTVYLVRVKGRNVYCLDRSAKPKILQIDPTEYRFKMALVKRNYEEMLHIIQTSSLVGQSIISYLQKKGYPEIALQFVQDPTTRFELAIECGNLDVAVEMAKELDKPKLWSRLSSEALAHGNNQVVEMCYQKLKQFDKLSFLYLATGDKAKLARMAKIAEHRGDFTSRFQNSLYLGDVEDRIQMFKEVDLYPLAYMTAKANGLEEECQSILEATGLTEDQLTLPDNLGGSLTPPKPVVPTYQANWPSKGTSVSFFEKALLGQVEGLSLEDEPAAANGGDAFGGEEADGGDAKKNGNLMDVDDDEDVAGWDMGDDIVADPDNDFVNVDSADAGGTGSSEADLWARNSPLAVDHVAGGSFETAMQLLNRQVGAVNFAPLKPRFLEVYQASKTYLPASAGLPPLVNYVRRNVDETDPRKVLPIVPRDLEFLVENDLQRGYDAMKSNKLEDGIKTFKSILHSVLINAVSSESEVDEAKKLITSASEYAVAISIELARRNLGANDVVAKDPKLLKQSLELSAYFTIPKIEVPHRQLALLNAMNLAARNKNYNSALSFANRILANGGSGRILETAKKTKAQCERNPNDAIDIEFDQFAEFDVCAASFTPIYSGTAYEECAFDGSKYHSKYKGSVCRICAVCEIGKHGSGLKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEM8</accession>
    <name>A0ABR3ZEM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBP2</name>
        <name evidence="9" type="ORF">Sste5346_003062</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="716"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="839"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="954"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1223"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1444"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="865"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="964"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1233"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1497"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1514"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1542"/>
            <end position="1552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1560" mass="173194" checksum="A33988C60FF624E3" modified="2025-10-08" version="1">MRSASPILYTAPAPCMVPIRTSIPLRTPSPVPKMVFPETAKLVFFARKAHGGKKKRTLIRAVMNPPAYQGTRSRGPVPLPLVEETPHIDLNRPGRLAPRWLQDFVSGDLEDDIDTPGDAFQGVGCASDTFRREKAREQGIHCRDDDTPPVIRHELLLKGHQSFQGEPPSSQPLRRADGSECDEVLACVCQNCRYHFTFYIDRKANKLCGAARGNNNSSSSSSSSSNANADPFHHLVYMRSETDTPRSINTKFYPFLGRGDYTCSAAQCTFKLTVEVSKPRLGDHFLAFLTDNDSISNRLKRAVEDEPERFADVANATPNALAYLRAYLRDIVEGQIKKNADGSEIERKIDQRNKKFFIQFGNGPEAAELLTYLGFEEIIDEDSRAWKVPSPTITRPTRPGSQLAFYQDVKSEVETILGKDSQSMRPNAAISFITNALDIGEFAISDRGYNEYRSKDYAFLGLLPRMHERYFWYAYTCQSQTNPQNRDDYFVCLKNLAQGRNNEDLEIHIQSYDSIRTRQPKASVAAAEEEEEIRLATERSLQDAQPPTVPIQMSNIDKVTQAYNYFGLDEGQRSDDEVLAKFLSNSDAYPSQKPNFREKLLLIARHTQSQNLQRIAVEDMGYKEALSYLGAEKDTDASYIISIAQFSISNDEKDRDVVVAALRRISKERGDDATIASAAHDLLNGQGGASATNVLNQTDADSLTNDKLYLDLALPAGLENIRNTCYLNSILQYFNTVKPVHEILNNFDELGLPNTEESLRARRIDPGSGHLEKGEAYAGRKFVEQLSKLFTKMHESETIYEVPTQRLAIGALKNSARLESDGKRLLAQKQEEQNHALTFDVVNTDRASSPAPPLPVRRAAAPSPTAQNTTVHVNSPASPMATSVLVPDADNNDSSSIMSSQTLVDQNDAQGQSTTDEGWQNVPKVSVSMEELPEDDTTEADVTIVEHAEQAEADVPASPDVTMTGTGDDATKGDAAAPAATTTDIQSRQAAADNVQLVFDPPPVAEPSVETIIELALEDQSVKGTDQQDVEEVMGNIISHLRASVKATGEDADTGVQRDLITDTFFWTSATYSRSDPAGRYNRQVQPNRWVTAFPEEKRKIGLLQALSNSFQREFITQGTWYERFTSIVDLPPILHIHIQRTKGDGTKNKSLVDIPQTLRLDQFMDCLEGSDLFARRRHAWNLQERIRSLKGPNGEEPPITFHPDSVGKAAAYNDLVVQDSIQQQDRAANEVSSSSSSSSSSSPCSADGSSDGDYDMLDDDIRELMHATGVEFEPPAGLSGPEVDARVDATLDEMFGDSEVNQKFLNESRLLTPDSIKQSWARQDLVGSANDTIRRLEPTRDDYERELEALFQDLKAPEYEYLLHAVVCHSGNTGKAGHYWVWIYDFDRCLWRKYNDMFVREHPDTEAVMKKLSNGGEPYYLAYVRASDVKKYVGVSLRKERSATPDNNVLDNIPPPPPRPQNRSLPMIPEVSTAPPVPSSDSRLLATPPLEADDSSELKELNEVNELKDLEQLKQQPPQQEPLIAGLDGQDDDANVLPAPASVPLPTPTPGPDSDSSMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEN7</accession>
    <name>A0ABR3ZEN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SDS23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein sds23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SDS23</name>
        <name evidence="13" type="ORF">Sste5346_003045</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in DNA replication and cell separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SDS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016711">
        <property type="entry name" value="Ssd23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018148">
        <property type="entry name" value="UCP018148_CBS_YBR214w"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="287"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="400"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="530"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR018148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="567" mass="59756" checksum="AE5D41C112950A40" modified="2025-10-08" version="1">MDSSTPPTTERAGSGSSSASSLTNPGGAAQAAVPGSAAAAVPERSPSRSSLRHSHSSSSHRHSFAENLRNPPPSPRSLRQPTFATQVQGLLNHPPPQRQPNPRFAGRDWHDISLGELVSEEDIRWASLDTSVEDCTKTLLRNNNTAGAVLVRNGASDKMAISTFDYSDLNAYLLVVIGMASPDPEHVAACQSIAQRAQERVAIPIRDVLPVCHKEPIATLTYNDDLLAAIEVFGSGARRVIVTNPNGTEVVGVLSQLHLIQFFWNEAVNFPQIDRLYASTLRDLRIGSQEIIAINADRPLSDALTLMNSEGLTSVAVVDNGLNVVGNISTRDVQHLTSVASFPLLQSSCMHFISVILSERGVEEGRDSFPVFHVNPYSTLAHTVAKLVATRAHRMWVVDSLSPSPSAPHTPLLSPVQTTSSSVSSASIATPSGPGHSRTPSGAGILGSPATTTNGTSEGGHARRESTVLTSSATTAAPPHSPIPASSGNGGNVPGFASVPASALPGAHLSGRLSGVVSLTDILNLFAKTTGLRPSDPADIRARRRRSSSSSLRPSLDGVRTSVDLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFF8</accession>
    <name>A0ABR3ZFF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamate 5-kinase</fullName>
            <ecNumber evidence="10">2.7.2.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRO1</name>
        <name evidence="10" type="ORF">Sste5346_002833</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="322"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="436"/>
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        </location>
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            <end position="453"/>
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        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1899436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="52631" checksum="ECFCA6A56C617422" modified="2025-10-08" version="1">MKGPRPLGIVIKLGTSSIIDATSHEPLIATLSLIVETAVRLRKDGHRVVIVSSGAIGVGLRRMDVEHRPKHLAKLQALAAIGQCRLIGLWDSLFSHLRQPIAQILLTRNDIADRTQYLRAQNTFAELFDMGVIPIVNENDTLAVEEIRFGDNDTLSAITAAMIHADLLFLMTDVDCLYTKNPRQHPDAEPIEVVEDINALEADISTPGSALGTGGMSTKIVAARLATSAGVTTVITRSSTPDNLVQILAHIQATQGSSLLQKSSSFASLPAAYAPSAFPAAAPSLSNSTTLTKPPLHTRFLPWPEPVRDRSFWILHGLAPHGTIFVDQGAYQALIEHAGLLPVGVVDVEGPFTENDAVRIVVVDRKPATDRATPAIATPSLVASGTEVGRALVKYSSTEIARIMGHRSRDIQGILGYQTSEYVAQREYISLFRRKDSRPASPSLRDKERDHHRVSPNQKAATVAVESPLHKVEGLTLNSDSGSASKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFL0</accession>
    <name>A0ABR3ZFL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003014</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="96"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
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        </location>
    </feature>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="293" mass="31456" checksum="23C5A3EFCFBAD92B" modified="2025-10-08" version="1">MSGAGYDAVVDVDDEGDLGHTDLREDLEFHPSNFNDSIPGGRKGINSGGLPPPATASGSGSGSAAGGKRFLWTLSFYAQFFDVDTSAVLTRCWAALYPRANFLDVLEGNADLYGPFWIATTVVFILFLSGTISQYLATTGTEPFAYDFTLLSGAAGLIYGYTLVIPVLLFLALRYFGSESANLLECWALYGYGNLIWIPVALIGWSHIDILNWVFVAVGFGLSIMFLLRNLYPVLSATDRQTSKILLIIVVVLHLGLAVTIKFLFFAHHSPVAKGPSPPADGGSGDAAPPAMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFU3</accession>
    <name>A0ABR3ZFU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Frequency clock protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018554">
        <property type="entry name" value="FRQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09421">
        <property type="entry name" value="FRQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="197"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
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            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="743"/>
        </location>
    </feature>
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        <location>
            <begin position="748"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="786"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1092" mass="116620" checksum="DCFA68B6AB093305" modified="2025-10-08" version="1">MAGNNTLYPNEPPHPQPLRQSSSSTQNTGSGSAPQTSPHASRANQRHGQSSRNDGLAVPSADNSHDESSEDQQRTKKPSRQSDASGRSRASIMTDAKKWFDNSNNNPTGAFDVSPPDATLVHANTRSSSSEDYRSVIDDLTIENKRLKEQLKRFQQNVNRDVLENEKLFEIKMHGLPRRKKQELEATLRDFAASLGDTASNDSASLRKREKSLASSKDQSQQPHHHHHHHHHNNSALYSSNGSRSKQASNSSSRSRPVDSAYASMSTGANSSGTSLTRHPFGGSKARASSEQKVERYLKDIPEGLYPYYGFNTLGDKEKKKLIVRRLEQLFTGKIGGRYTGQAHSTAPDSSDLAGTTTIAAAIGDRSAKNSGALNSDSRSGSSGEGGSAPAVNAIPYASTPAVPGSATAKLQIPTSMGASEPSREARIQARTSGHKQAKSHDNGSASNSNGEEAGNGNGNGSGTVLTMSGATSVKGNGNGSGSGSGNGNGNGKSTLGSSLPDQRPTRLLDLDPDRVQVPADNMEYIRHLGLIPPEIGPQSVAKTIDVSPDADGWVYLNLLANLAQLHILNVAPDFIRQSVVEKSTKFQLSPDGQKIRWRGGMDGTKFSSDGGSTGDLSQHSQSTDVDDGSDETGQRKRAKKSGNGSASALSSSKKQSKTGLQDSAASSSFQYKPLFVHRNSVPILTSGEEMSSQESDQPETSHAFGSRMDQSNTKSRNRNDAKSRSKSNNSISNSNNNSNSNIDASRYGTSRSGSSNTRKRRKSDGVLVYYSGMPFCTDLAGDSSGEVSPATNETSTLQTQDSMDEPLQNRPTVHRSSSGSHIPFRPLTDYLSLSRDEWAGLGLLGIGTVGRRNEPAASANDNVSSSASFISSMSNQDDIDDDLVVFDYSSATDASSVDVEEPKLEASGIHRVFPEDHFALRVTTQRPFHSNGSINNCEDDDDCDKSNLNSGSTPSGDTFSIASLTSRVAALKKQTAPVSAAVAMTNKAPSVRINYVSAIYQQREPAKLPRPAMFYPPFSSTSESEEDTDMLDEEGGEEEDESMLASSSVISRRANPHHSVNNASLASHAVMSSGEDGDVEADEAMELEDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGI9</accession>
    <name>A0ABR3ZGI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1295 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41211" checksum="478FC07C59867093" modified="2025-10-08" version="1">MALPPVRSLAACADYANTVEPFLDQLYSLPGDFVAALTSGKIGQLYVDTNPLVSGFAISLALGFVFLVVSEINRNYSQVDRCWSLLPTFYIAHFNLWSRLAGVHRARLDAALLYSVIWSIRLTYNYARKGGYDVGSEDYRWEIVKAAIPKWLFHIFNLTFIAFFQSVLLYAIAAPAYTLLLTGTIERGLTFGDIVFAATEIGLIVFEYFADQQQWDYQTAKYKYRDTGKITAGFDKARLDRGFLAEGLWAYSRHPNFAAEQSVWIVLYQWSCYATGTLYSWAGIGALVLVLLFQGSTGLTERITSGKYPGYKEYQKQVSMFVPTSFEGFKTPSPKVIRTSDLAKKQAEKEAKATGNQSHNTRSAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGP7</accession>
    <name>A0ABR3ZGP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168827" description="Cell wall protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="43938" checksum="7E8F5861F273455C" modified="2025-10-08" version="1">MYYSTALAALAGFGSLVSAAPAHKVHDIFARAKNNNNNNNNNNNNGGASIIGVSPAALLGGNTVIIEQTILQPQITIVQENLDLVSQLALVAEQEFSALVQSQLALVNEVETIKNNIRVNHFKARFSQVNTVIVCVTELVDLRGGAGGRNSRYMINQLLADNGQAQSSVVVMLTAANPVTINAAQPTLDLAGLLGANATALPSGVVASAVAAASASVAASASGAAVVGNVNGSAITSGLAGNVANFDPANPFGQINQTVILPYGSKAPALPNGAQVFVDPANIILPNQGALLVEDINQFNQDCALWNANGLSLFNLQSSIVAAQAIAALEAGSFSLGTSSSLNAAAAALLGAAGAGSIANIGSAGVSTSTTTTVAAASVATSAAAAAVAATSVAAAPAAVSTTAAAAVAAGAAVVSSVAPVASVAPAASAAPAAASGGGVGVQIVPIQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH90</accession>
    <name>A0ABR3ZH90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit TIM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Presequence translocated-associated motor subunit PAM18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PAM18</name>
        <name evidence="11" type="ORF">Sste5346_002807</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TIM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763:SF28">
        <property type="entry name" value="GEO10507P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="J" evidence="10">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="105" mass="11144" checksum="79C2A33A6E22B135" modified="2025-10-08" version="1">MASAVAIGAGVAVAAFLGRAGLVAFRRSRGGVGSLGKAFYKGGFEGKMTKKEATLILSLNERAVTKEKVRKAHRTLMLLNHPDRGGSPYLATKVNEAKELLEKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHN6</accession>
    <name>A0ABR3ZHN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="595" mass="66062" checksum="6EC416FCAE5A0ADB" modified="2025-10-08" version="1">MAGPGGGPPRRSHTKSRKGCETCKRRHIRCDETFPQCRNCTKHKIRCPYNDIPVSEDRSVSPDRPEMMWTPEIEADIARWQQTGIFPFPALNIYPEPNPQYLSVESLRLIYHVASICHQLRSIDADGFTIWTRQIPTIISIGATNAYVMHALLAFSASHITYLNECPIVGIMADEHRGIAMKGLQEAISTFSRETSDAILAASLVLSWQATDWRSWTQLMQGTRSVIEAMDPWKHESQFGDFIAESSTFPTAPPSPVPDHKPSQPRKEDLEVFTRTIQQLQKVETFLKHSKEDFQAISQLITFLKGARKESNTPVAQQFARLRPLRDWLFWTPVRFFQNAGASPSSLISVAHLYTVALVMERLFPEIGAAYFGSLSIGPVEEIARRLLSINVNSAYEGDVQTPLTLMEFSIDVVSEFRSRMGWVNPTRTPSFPQFNPPNFYPHNPAVTSVAAGSLSMSAPTAGPAEYHHMPYGSESIVGNPAFSYSTEDLSMMSADPNNSSAINPLQLSSPYTNQYLNIPSPSYGGYSPASSTFGDFGDRSSVAYSDTDDFNSYDMTYASSSSRSATGGVDHTQMMGGPNNFGVGFVSPLQTVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIU7</accession>
    <name>A0ABR3ZIU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="58057" checksum="448C03379358FE69" modified="2025-10-08" version="1">MILDNFLWTGSAWTSAGLGLGLVLLAYIAASTIKSWHRLRHIPGPPGAGFSKWWMLRNTLGGNMHLATKAACREYGPLVRLGPNQLVTNDPEVLRRLWAVRSPYKKGPFYEAVRFNPERDNLISMRNDALHNELRAKMAPGYGGKDNESLEAAMDKEILVFCDLLERKYISTETDYRPVDLARKVQYLTLDVITALAFSKRFGYTEQDTDLYSYIKITEDSMPVMMFLSIFPGLAKVLQSRLFRRLLPSEHDHVGFGRFIAVAKQIVGDRLASDQPHRRDMLGSFLAHGLTREEAEGETLLQIIAGSDTTATALRTTMLYLMSSPHSYRKLADEVRGASAQNCISLPVVTDAEARTLPYLQAVIKEGLRINPPVAGTMDVVVPEGGDVICGYTVPAGTEVGCSEFGAQSLSTIFGPDADVFRPERWIEAEKEDNKDGGERIKQMNNTWNLIFKYGKWQCLGKEVALIELNKVFVELLRRYDFTLVNPSKPWHSINAGIFIQSDLFVKITRVEAAKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIY6</accession>
    <name>A0ABR3ZIY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 11">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TPI1</name>
        <name evidence="12" type="ORF">Sste5346_002487</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 11"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF41">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="252" mass="27093" checksum="07C967A102A6D736" modified="2025-10-08" version="1">MSSRKFFVGGNFKMNGTIKSIKAIVENLNQSNLDQNVEVVVAPPSLYLLLVRDHLKPQIEVAAQNVYDQPDGAFTGEISAHQLSDSNITWTILGHSERRTLLGESDAVVSSKTKYSINQGLGVIWCCGETLEQRESNQTVAVVTGQLAALKEALGTDAAAWSKIVVAYEPIWAIGTGKVATTEQAQDVHAAIRGWLKENVSPAVAEATRILYGGSVNDKNCKDLAKQADIDGFLVGGASLKPAFVDIVNCHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ62</accession>
    <name>A0ABR3ZJ62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002409</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="390" mass="43265" checksum="49F75808B27806C2" modified="2025-10-08" version="1">MAALFAQAAPPKSALGRYRLLSPQAGVRVSPLCLGGMNIGDAWKDYMGSVDHETAFGLLDFFYDNGGNFIDTANNYQWEESEKWIGEWMEKRGVRDQMVIATKYTTNFRHNNAGEIQANTSGNSTKSLRVSVDASLKKLRTDYIDILYVHWWDHSTSIPEVMQSLNQLVVSGKVLYLGISDTPAWVVSKANEYARNHGLRPFSIYQGRWSAATRDFERDIIPMAREEGMALAPWGALGGGAFKTEEQRRIQQEKKEGRQVPASPEAIAVSRVLEAVAKRHNTIITSVALAYVMQKTPYVFPIVGGRNTEQLKSNIDALSLVLTKEDIAEIEGAIPFDLGFPHNFLNGGMPGNISTPNHYQNGGLLGMSAAYDYVPEQKTITIPKDITKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJI0</accession>
    <name>A0ABR3ZJI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="18701" checksum="AE147552AF08682C" modified="2025-10-08" version="1">MGALTKPPRVVQTPQEQIHRARAQQVLTAERQNLYNTFRTREGAKLTALFEEYVRALALSYEAPRAAAARAPRHRHASPYLCRKSLSTFPTFTWNGHARQSLVCHARDDTPPRHTSAYDSTSYRREPAPCAASRMPAGLGGPPSGGGHSGVYWRRILVRVGWPLGDGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJV2</accession>
    <name>A0ABR3ZJV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="4">2.7.1.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MSS4</name>
        <name evidence="4" type="ORF">Sste5346_002223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="573"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1117"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1247"/>
            <end position="1264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1290" mass="138161" checksum="4114D9DFA79611B8" modified="2025-10-08" version="1">MPSFAHDEENCPVPTQSLASATSTTASTTNAVPGDGPAAVFGKNVTTRITSHALAPVDANAPSSTTVVNGRGSPVRYSPPPPTSPPPSPPSRQAPLPITQSKPINDRPLFFSRKRSSTFIDNDDDDYEDDNASAASSADMTGHGGSTRGGGGSSSVGAASSQTTTGPPDEDLRFDGYGGSSLYEKDNDMNNDVNLNGRTASITSSNAPSIPERAPPPPPDNKPPSLSSLQHIPAASSPLLSPIPTQMAASSPLNRPEAPSLPPPPPPKPDSLSRKTKPLPNGGPISVPNPMNLNLPDRTRVNNIPHSQSQPLPTQQTAWTNGTSTEESELTDTSPDDTFPRHSVASTGASSVQPSIADLYSARQAGSRSSDQYGTSSAGPSAAAAASSTPVPPTTATTAATPESTSASQFSAQSPNPQFLQTGQSSIPPHRFSSPPAYNPAAGPSSSATGTHLSPTAGLKHRHTLEVPKVSPARNSREGFDPSGAFASGRFSPTAAGGVGNGSISSIGGRRASLSLVRRNTRSLHSDLPRDEVVPDEDALRWAEAYRQKRASKKRRMEQDDDQVLVGTKVDETHTNWVAAYNMLTGIRVSVSRTNAKLDRPLTDEDFNAKQKSTFDIAGNELVPSAKYDFKFKDYAPWVFRHLRQKFHLDPADYLMSLAGKYILSELGSPGKSGSFFYFSRDYRYIIKTIHHSEHKFLRKILKDYYKHVTENPNTLLSQFFGLHRVKMPYGRKIHFVVMNNLFPPHRDIHQTFDLKGSTIGRDYPEELLSENPRATLKDLNWLRRHQHLEMGIIKKRLFLEQLHKDVKLLQRLQIMDYSLLVGTHDLRRGNDENLRGKILQVFEPRGDNQNADGPGAAQSVLMRTPSKLEHQRKTRELRQMLKSERPIPIGQSSNKMPDELDDNKQSIFYKDDGGFQATHQDNTPAEEIYYLGVIDCLTHYGIVKKIEHFWKGLSNDATQISALPPQQYGDRFLKFMSGITMSPEDVAREAQDRGEAAAADAAASAAQNGDAVGNAGDGAGFDGVATASGRDKGKDAAGHHHQHGGWSGNLRHRGGNSNNANNSGIGSSNPTTSHRAAEDEADKTSPVNETETTQTTVPIGNGTLLPGLVASPTGQSSTSAPTLPSLPSLPSMSSIPSMPTSSPPAPPHNDRRESMQQPVLPIVDEANENSSMGGRSRSSRFSSHTTESDDRPATPAKDVPAVPGQYGGGVGVGGVRLSGSSGSHHRDNSPPTPPATGCLKPESADSGYGVSGTRSRSGTVGSGRKVKMQMSRDSLDKELPPLPKLDGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK51</accession>
    <name>A0ABR3ZK51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ENV7</name>
        <name evidence="13" type="ORF">Sste5346_002320</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="32"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="175"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="366"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="439" mass="46155" checksum="8C4301C9D8939B7F" modified="2025-10-08" version="1">MASTILDLVYSMGSCLSCFPSTPTLKVNGRSFKILRLLGEGGFSYVYLVQDNATAELFALKKIRCPFGAESVAQAMREVEAYRLFARSEGIIHSIDYSVATERGGGGGGNIGDSGGGPAKTVYIVLPYYRRGNLQDLINANLVNHTQFPEKQLMQLFLGICHALREMHKYRGSAATAAGGGSTNDEHMTVPQGGASSSGAGGSGAGSAARNGGDGRTAGADDEFEAEQQRPLMGEEEPGARVGSGAGRSYAHRDIKPGNIMIADDGTTPILMDLGSIADSPLAITSRSLAIATQDVAAEHSTMPYRAPELFDVKTGGIIDTKVDIWSMGATLFACLVGKSPFEMRSDETGGSLAICVLSGDWRFPDEGPGGKAKPPKRTGTGMSASGTAAGAAAAAAEETTISEPVREVVRRCLRVEPAERPDIDELIHLVEDTLDQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK58</accession>
    <name>A0ABR3ZK58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="38550" checksum="7A31B610B2933768" modified="2025-10-08" version="1">MASAPFDTPVPERPPFDSLPLNPNGPPGNAWGLYGDNDRLGALNMLTPAVVAAAARQEIQTGERVSLDWSLNKPSHPSFGRPPLEWKRIIKKDVHGNNRTVNDDYLAFNTQGSSQWDGFRHYGYQQAKRFYGNVAIEQLEGAPDVIGIDAWVEKGGIVGRGVLLDYAGYCKAHNIDAPPYESTPFTVEDLEKVITFQGGPELQKGDILFIRSGCTEAYEKMTPREQQAIAERPSPNFIGLTSTKTSLKWLWEHNFSAVAGDAPSFEQAPLAGPHVVPGHTELSTEDEEKMKGGGLIHQWVLAGWGVPIGEMFDLEALAAKCKERQRWSFFVSSVPLKVPGGVASPPNAIAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKP7</accession>
    <name>A0ABR3ZKP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056948">
        <property type="entry name" value="PNGaseA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25156">
        <property type="entry name" value="PNGase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal" evidence="3">
        <location>
            <begin position="150"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="754"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="776" mass="82200" checksum="2E3E1D3F13AB2A35" modified="2025-10-08" version="1">MEEAAAPLLEKEHLVALDPEITSPKTARSTRPARPSRPSWRMRVLAILLPVGLALTVVLAFGSHYRPCSSSLRGPKRPAIPYADHLPVSAQISASKRAEEDASPSSTSTIVAVSTPPASPSATVLDCFQVAPPVLTPDGPATERSPGPSSASGAVTVELMTHVFGNSYNAPFVGSYTPPATAFNRVVMNFTVVSEGRQFDRLALMYLNDTEVWRTSTAEPVKAPGIRWVYLKDMTAYLALWRTPQKVIFDLGNLQNDVYTGSFNASLTATFFQSDAGDHVDTAPPSDVVIPISKRKSDVNAVSQFTLPADVATNTITDFPRNARRAVFSVSANGQADEEFWWTNVLQSDTTTFNATGGGIFPGFSPFREVQVLIDGQLAGVQWPFPVVFTGGVVPSLHRPIAGADVFDLREHEIDISPWLPVLCDGEPHTFAIQIAGIDDNGQPSGEVTLTKQVAASWYVTGKIFVWLNNEDGDDSSALVTTGTPPSIQSSGPDVSVSQHLQQNATGANTTLSYTVSVSRSFSVQGSLTLGSKGSRAVSWSQSLSYANEGILTDFGANQINNFSLTGSDKATGSGGSSGVSAYAYSSDYAFPTFCNMTTNVSPQGNLTLWALLDQGLRLQVTGAGVFPTGLEAFSSSGQRYTGSLLDTRAVGTASFFQTGDGKNSSGFGTTNQYMHFGGFSSAGVLGATTPDITLYERNVTAVNQTITYDQETVAGVSSTETSATVPSSAGRGPSYQYAQAPLHPGTGTRVFMGRGGADPAVAVDPSTDSQSPLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL75</accession>
    <name>A0ABR3ZL75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="847" mass="94916" checksum="94B61EBA43CE3C3F" modified="2025-10-08" version="1">MLGAQHYGKWRELIFDYDRLMFESGLAPPSVYPEDAQRSVDRPENAADISLWSAIFNFAQRRGDSDGALVVWREIFQRQQLYQVDGVVANAFWMSVVTAALEAHGSSFLESTWAYAEWMHDTHGRLWPHYYRLVVSSFLDRGDYNGALQWHLRLSPHFSLPKRDFFDLLKTYITDPHPELQETLQYIYVTGRHRALYDTIVPLLWSRGRSAVARAWRETLVRHNDLPASSSSRPFLQFVAGYYPETELTHQEQILVNSRPSQYLSPPPPKPAPKAPDLPTNLFHLMNRVHGETFGIQEKAFNDKIGSKWFATKWVSLDTAINMLYSLGVEEIGPLSLQSIALRSGDLAGVLRSLEHLEQCHIGVGNANYSKAIRYLARMGDAETLNELLRSELHPDVFDDIVLQRQVLGSATYIGDWKTHRLVLAVRLAVSEDALETTSNKLLITSLSQKKKAFALRLLDEFSARSMEVTSATCESVSEIILADAPRKFDPNDAPDVDFYAALCRRLLAMRLPVATEVWQNILLIYGRLGRLDDLEKTALDIVDQYVSLQTTRLPQKPVSSATSSPSSPSSKSSSMILSSSDETAAFKVHIADVPDIVRGETQKLVDVGYRLLPRDLPLHHPLHPVSLIFNEDIVPSIVRWYFHRRTAYRQKKGARIVSRMRPAKAAAKKAADGSIIPKKPKPYTPAPPSDAAPSDFNLAGGIRLLAMLHERGVDISMQTVRSETLICIVALFGPESMSTRYWQPSRAANQLKLGEVKAFCDAAWASGDEIAEHLEVNMAEETDEDAAISSEKPTLLPKFRLLKKALAAVKPVAASFANQITRPGDKKKASRDAFMDVISKKAATST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLA4</accession>
    <name>A0ABR3ZLA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="150"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="542" mass="57931" checksum="C061A576FC5EB253" modified="2025-10-08" version="1">MAAQTDVQPSSASQSTLHSNTHIDNVNMASTAQSATAAASKEEKGDSSPYNDASRRSSTSSYRRRRSLERIPSQNNETEANLYPEPNNVVEADLEKGGYGPEESDESPKEKAAASSGADSKTADGEAAPAPPAAPPGMSPADFPDGGTQAWLVVFGGWCGLFCTFGLINCIGVFETYYVTGPLSNYSQGTISWILSVETFVMTFGGLVFGRLFDTYGPRWLLIIGTIVYIFGLMMTSLASEYYQFLLAQGVCAAIGSSAVFNACMASVVSWFFKRRAAAFGIMVSGSSLGGVVLPIMFDKLIARIGFPWAMRAVAFLFLGLLIISCLTVRSRLPPRPKPLIIRDYLKGFTEPVYALTVFACFLFFWGMFLPFNYIELQAQAAGMSPTLLPYLLSIINAVSIIGRIAPGIIADRLGRYNIMIVITALSAIISLALWIPGKSTGAIIAYSILFGFSSGGFISLGPTLIAQISDIRQIGIRTGTAFAVQSFGALTGSPIAGAITSRQNGSFTGLQFFCGFTMLASVIVFVIARIVLAGPNPMKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE4</accession>
    <name>A0ABR3ZLE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="274"/>
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        </location>
    </feature>
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    </feature>
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            <begin position="355"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="379"/>
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    </feature>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="1271"/>
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        </location>
    </feature>
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        <location>
            <begin position="1285"/>
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        </location>
    </feature>
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        <location>
            <begin position="1388"/>
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        </location>
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        </location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1607"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1634"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1671"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1742"/>
            <end position="1755"/>
        </location>
    </feature>
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        <location>
            <begin position="1764"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="1811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1833"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1851"/>
            <end position="1860"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <begin position="1905"/>
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    </feature>
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            <begin position="1925"/>
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        </location>
    </feature>
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        <location>
            <begin position="1949"/>
            <end position="1963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1975" mass="205808" checksum="F82143829B0C932C" modified="2025-10-08" version="1">MDRVRGGSRSRGSAGGSAPPSHASQNMAQSPHSTHSPLTASPPASPTAMATSTSNSSAGAATSAATPSGGRAGAPPVTRRRSSRANDSDPPMTPAQSYAAAYRAALEAEELAKSQGKGGHSLRKRTRVDYQHMDNGDTSATSTSANGEEAEQDNPTSVSAAEQIEQNEQTPSAPATRGRKRKTVHIGFRTGNTGEDEVASPPSPAMATKKIRLVHHQPASTEGASTNGTSTTATANGHAATSTPAATVPAAKASETAATPTPTPRGRGRPPNRRPNGPAVGTQASGASTAGGAPASGTGDTASPMVLESPSGGAIVVHDTIRVGGSPPSSDTEADNSNTHSNTSSAGATPPLQRSASSNSVTLSSSVQQSNIAKAVHQTAAAPSATSSTKAKGPTSAPSTAAANGHTPGKVGRPRRQSTAAAAAAAAVTSTPTKAKAASADTSPASKVSLSKNVSPQKRGQHHRSRSQSQHRLMVRIPRGRNRSPPSVYHLQTAADQERFDAFMEARANDAKAGAAVLPSYESFDSEKTLKVEADNHDSEETVAKVEPEETPAAVDSFDGATDVEANKSTDVASGEKKNADADVEMEDSHALDMSAADATTTTPANKARSTASDDVMDDAPSPVAFRSMTRRTSTRIASAAAQKELAILEAHEQTLKEQKAAKAAAKAKAASSTASTSAPTSAHNLFATGRNVRRPSGPRSWESLTPFENENVFYPEQFYDNVTMATTTSLAAPSATPNPETSAETPEKTESAEQADQADQADAAAAEQSTPLPLAKDGIDTPVATDLEAALQEKIAADTRLEEAAAAAAAAGTSFASTVATPDIVIDSATGSNSATPAPPTPIDLPTASADLTVAATAPVTAAATPNATSEDLETETPTGTTSAPAANAAAATSSTPTPGRKPMWKKQYRFNKIRDPKEFVDALKDHKDMSTDDLFACLAHMNDTLLAWQEEYKLLRGIADDEENAVRRRQQDATFENRTLMALKRGNVDTEITERDFVVKGIRAPESLADPIKRHARQQDRLMSHIYLFEHDPRDSMISRQDPVAQREGLQNTRLRNRPKQTLKAAEAEALDDGMGVGRRTRRNRKAALDDESGEGSRAGTPVPTSAPTVSAPAPTTATPANPPVRGRRGRPPGPATLAAKAAAAEAAAQAAAAAAAEGKTDDDDAQTDSAATSGVAQTPTKRGRRGRVPRSQLSESVAVDDLEEEKPSTAATSTMPYTNRRASAANMPPPQEKPSATTSTTVSPLAGGPGRKRRRGRKPNSLLRQEAAEAAAAAAAAKGEAGDEDGEGDDDNGNDGNDGDATENGQDPTYDDGDETATESPQHHDGRGHNGYGSGRAAAAKRQRTSVLLKKDGTPDLRRRRTSEIGPRSFYSTGRDNHDEPTRPGSSASSNGNANNANANNADDSSYALRPKRRRKFRAVHNGVDDEEEQDEQKEQQQDNAGEDTTANGPPTKKQKRRRRTTTQSIQEESANTSMQDVGTHQEPQSVHGTPAPQDQQQPYPPPMHSSSMPYDPYAQQQPPHPSQHQQQQPPPPYGQQQYQNQQQQPPVAQSQQPHQPHQPPPPHHQQRQQQPAPYYGHGPMDGHPSASAAYYGHHAPPPPPPQQQSGYSMSPYGQPMQAYQSQPMYYGHGQPPPPPQQAYHHQPPPHQQGPPGPPGPPGLPQSVNNLAPAPQQAQQPPAQAPAPPSSGRQRTTFKIKNYTPAPVAPSAGVHAFTQMMPNAKNGPNTPGSHRHSLGGAPSASSTPMVNHTQFVPHTPSGPGSDHGGYGSPGVGGTPGGPPGGSGGPGSTPGADGDDKDYRQMTKSEKMSHSMKTRWANGSMQAAVAKRKATLAAKKAAAQQAQQVAAVTGGGHPGEGKGNSNSPNDSLGPQAQGPGSTTGSISGPPGPPGQGPPPQGPPPHMGGPQHMDYGAPGPYHHHQQQHPDMMQAQGQGQPGPYDHPSHSMHGHPNNSGHPHNNASAMYPGPGSSRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLJ7</accession>
    <name>A0ABR3ZLJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CPAF-like PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972449" description="CPAF-like PDZ domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="3">
        <location>
            <begin position="242"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="857" mass="91305" checksum="33AA02E52925DCEA" modified="2025-10-08" version="1">MKTVSLASIVALAVGAAANECNADNCLRALRATQTPGRLQSAQAFCSQYTATPSASVAIPSYAAAACVSNQVGPLDVRLSSACSCIAPATTSASTTVTSTPAPTSSASPSATEPCAIASSAWAAIQSANPEAAVSIPAELAYNCLRSVPLHKDEAVQLVDAIAPYLEWQTDAAYKADPPADYFYPPYDMFDALAKVRSNLVNDVYDSEYAFQIDLYLKVFGAGHDGHFVMYPDLLSKAFVYTRPRSLVSVADESSSSKLPVIKVYEDIVADPATASEVILINGIDAATYIENTIFTASFNQDADSAYNSMFFAKAVFGAGEGSGYFSAGGRIRFNYQGPTTTFTFANGTEAVFTNTASVLSSLAGITDGESMFQTFCSGANQFKAANQPVSSSQSPYVPTSASSAAPSATPTGTSSGGVTVPGFPEPVDITDDAIVSCYFLDGPGFEDVAVLSVLAFESESPVEFQAVQRNCIAQARAAGKTKLVVDFSANGGGYILQGYDFFRQFFPQVVQDGYSRWKANDAFVALAHIISDDVATLDPYTSSDAGLIGEYETWFDTRYDLDINDKPFKSFDEKFGPYVFQDTNYTAITRWNLDDPLTTTNATYGMGMEISGYGTLANLTQPFAADDIVLLYDGFCASTCTLASEMLRIQGGVRSIAMGGRHRAGPIQGVGGIKGAQTLAFSDVYGYASSGLPEAENDEQRAALARYNELPILRSSAAALNTRDQILRGNVLDGLPAQYVVEEADCRLYWTAEMATDVTAVWKAAAQAAFNQGKCAAGYIAQSTKQPPPPTHYKRGLAKEALEKRRWTAASEASLARRQAVAAAKARGDEGVFVKRDVAAKDVQRFNAKYNQKAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMK6</accession>
    <name>A0ABR3ZMK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GPN-loop GTPase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17872">
        <property type="entry name" value="GPN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030228">
        <property type="entry name" value="Gpn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF7">
        <property type="entry name" value="GPN-LOOP GTPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="296" mass="32822" checksum="43944E63E7AFB082" modified="2025-10-08" version="1">MSKFGVMVMGPAGAGKSTFSAALITHLQLNRRSSFYVNLDPAAETFEHTPDLDIRDLISLDDVMEEMGLGPNGGLIYCFEFLMENLDFLSEALESLTEDYLIIFDMPGQIELYTHVPILPSLVKFLTRAGSLDIRLCAAYLLEATFVVDRAKFFAGTLSAMSAMIMLEVPHLNILSKMDLVQGQVRKKDLKKFLTPDVQLLEDDPAAAASGIDDSEAVVADPQDKAQLMRGTSFRRLNLAVANLIDSFSMVSYLKLDASSEDSVGSILSYIDDCIQFNEAQEPKELKDDEFEEEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMK7</accession>
    <name>A0ABR3ZMK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF25">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="204"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="741" mass="81666" checksum="ACF80ADDC1D43878" modified="2025-10-08" version="1">MSDPAKPFNNGNGADEKEFAGLANTQTNKVSTQHQEDASTATGPTATGTGVPGASRTPSSGGDDSAADLHERQAWSHKLQNPLAGIDPEELANMGEAYARKHNVGIKKGETGTVSDEDIRAFRLGAVIAANPQMYTGGAVASSAEGMVQPQTEGVTGNVGASSSQEKQVYGGGPFYDQLTDSERNALAREETHKWSNPKHLYAVIVICSLSAAVQGMDETVVNGAQIFYKSAFKIDDPNSSYDSWIVGLCNSAPYLCCAFIGCWLTEPLNKRFGRKGTVLIACIISALACFWQAFTNTWYHMFIARFFLGLGIGPKSATTPIFAAECAPPKLRGALVMQWQMWTAFGIMVGFVADLAFYFVPDHGIELGLNWRLMMGSAMIPAVLVVALIPTCIESPRWYLTKDRHADAYASICRLRFEKVQAARDLFYMQILLEAEEEILHGKKKAAEAAGQSRGRSLLKELFGVRRNRNAVIASEIVMFMQQFCGVNVLAYYSSQIFLDANLGQVNALGASVGWGVINWLFAIPAIYTIDTFGRRNLLLTTFPLMAIFLLFTGFSFWIPDPEDGSSKARIACVALGMYLFGMVYSPGEGPVPFTYSAEAYPLYLRPIGMSLATATTWFFNFLLSVTWPSLLLAFKPQGAFGWYAGWNVIGFFAVLLLMPETKEKTLEELDAVFSVSLRRRVAYGWAQFFYFFHRYVLFGGKSVVAPEEPIAEEFQHMSRPDYEKRPYNQETQRDATARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMN0</accession>
    <name>A0ABR3ZMN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="264" mass="29656" checksum="DDD7437B7CCA48A2" modified="2025-10-08" version="1">MVFSNAADVLYRLERVSEGDINSSNTDTLVVSNVSPTDFQALEAKRKTSEQRYRFSYFADTKAAILTAPTAAHEQMHIALYIHLMDAMCKMEVLDDWQWTASATVRAATGSSGEADTAGSPVHYRQEEGWPTLVVQTGTGSSSQTMHALRQKARWWFTASHRQVKVVLLVSISVQEAKLRIEKWTDQTAEGQQQTIEVSWTGPGPVHQAPLEDRYDPKFFWVEGGPLELKFADLFLRKPKDDEHDIVLSEGDLQDVAVRVWSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNF4</accession>
    <name>A0ABR3ZNF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Quinate repressor protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001204</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the 2nd section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF17">
        <property type="entry name" value="QUINATE REPRESSOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="5">
        <location>
            <begin position="502"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="4">
        <location>
            <begin position="640"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="837"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="839"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="860" mass="95889" checksum="6C7498C4A735412E" modified="2025-10-08" version="1">MALPLSTPPPNKRLFDPDATIVLVGCRGAGKRTLGFIGAMHLRRRLITEDHYFEQVTGVSRGHFLARHGGEAFSRRNAEVFRQMLDSNPRRCIIECGMSSLAEDAQVALRAYGETHPVIYVHREREQILRFLDAADADQLLRADQSHRQCANLEYYNLYDPYRGRSSATGSNGDSLATNSGANSPWEQYQQNSKAGVNGIASGKNSPLAGSSSRLFYAKEDFTRFLDLLQEHPWRKQWAESPFSINALPPEFRAYSYTLRLRLSDLLDMDMELEEFEARGDCIELIIDTWPDDMLSVIARQVALIRRKLDVPIIYNVEEKPREERTRPPEERDRVDTELLELGLRLNVEYLSLDLQRSNELVRHILARRGRTSIIGNYWYPGLTAPQWSSFSLVQNYERAKRLGCNVVRIVRFCTGGSSEEEPLTFKNRIAQTVPDPKPPLVAYDYSLLGIRLPLQGRILNPVKHPDLPNRRDHLASVATSKSATLMQFQTGKADALNFYTIGSHIAYSITPALHTAAYNFWSMSHKFQTAECTTLDDLKNLFLSITSNGNSTFGGATLASPFKITIRPYLKLESKHATAVGAVNVILPMRGHSDAVIEHVKARNKAGACNEFYGDNTDWSSIYKCIQRALSPRNVVQPSRTTALVIGAGGMARAAIYALIRLGCRHIFIYNRTPQNALDVATHFNNWFQSQGQSPSTAAAMNGNSGAGSSKICHVLATKSDPWPAEFQQPTMIVSCVPVVNTDGSAAAGFEMPRQWLQSPTGGVVVELAYEPLITPLVAQMQNIRDTVSPAWVIVDGLEVVSEMAIEAFELMTDRSAPKRLMRSVCRQAWDQQQRGMSTSTSSYTMSAPTTVDAMTDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPE6</accession>
    <name>A0ABR3ZPE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24466" checksum="D707B967B9D63823" modified="2025-10-08" version="1">MGKRPADEAGGASSSAAPHKAKRSRTGIRAALPTSDDAWRRKLERAKESNVIRAKTLQTYAKVKARALAEACEKDGKAEDNDEAAGMHPDRQARIDDAEAGGDDKEEETGEKRERRPRGAGSRPPKRPQSFFQKAQEEAAQRKAEAEARQAEFERRQAEREEAMAQRARNQKAMAKARRVDTRRGAGNGGGFKSSGGSDNQRRKLGRESGVLLVKVRRMMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPK9</accession>
    <name>A0ABR3ZPK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="67246" checksum="A903AC2F105D8FB1" modified="2025-10-08" version="1">MFSSSGVNSPDGEAAGARPRNRRLNASGTTGNGASTSSSSASLSAGGGGLLSPTSANRSFSNLTDARNGSGSGYGTAASSWVPNWSSIQEFASTLLAGNGSTSSGSGSISRSRSAGARPTERRDGNSSRKLPAAWGPAPPDKMSSPSRPRIEDVAAGQVAAREAELKARKTASVLESHPGVNGGLDVRGKFKHRNSDENLRSSAAEAAAAQEVEDCLAYIHRVQATDTYFGIILKYRCNEDAFRKANGLWSRDNIQIRKWVALPVDACEIKGRPCDDPSLFPQGVDLMASTPTPRGVLPPLSQVANGVSNGDYFGSPAAGSSKASLNKSALDDAVAEPPWTHVRWVRLDSSPNPVEIVRMSRTTFGYFPPRRKKSIRGSVSSVSTPRASLDISLSNASLPERPIADSPNRSSRRPSLFGQRVALGTPAMSSSPSLLGRTGTNTPPVTDPRPEWMRRPGGVGSMSKSVRAPGPARDSLNKWTTKHLPGLNIETLPSMSVMGSETAHFGFGDEQQRPGIVESSFEDGRDASTATQKDNGLDKAAASIETWLRGAFAKRPGTPGSAAGTPSTSFAGRIGRQLEETLGDLIELEDGPREDGGSGGAGSSSQASRPNASTGWRADSEGSLRGRSTVAAAGRAKGKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPN4</accession>
    <name>A0ABR3ZPN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="28622" checksum="74E258DC68162830" modified="2025-10-08" version="1">MSDSPFTGPGVFWISSNTSDEAVFPYTDFVRWYEDVHIPDVVNADPENPLPVERRYELVSGDTDAAAKPFLVIYKLPTLSFVTSEAFRHIPLHHKQIPEDGPIAKFASFRGRFARHVETWVGGGATGTLLLSEIVESSNVNDYSECMSTVAGLPGWQRSTHFEVVMENEIDKDKAPPAGGPAPPATTSTDKPPRWLTLHEFDEKRLEGVGEVIAKLESSLLERKGRADEDIFELVPYRLVRVYGDKAAAFADGKDTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPV6</accession>
    <name>A0ABR3ZPV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PDX3</name>
        <name evidence="11" type="ORF">Sste5346_001577</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="9">
        <location>
            <begin position="106"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="10">
        <location>
            <begin position="266"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="313" mass="33910" checksum="2C29C34E10A04BFB" modified="2025-10-08" version="1">MALYPPSPAPPVAGSSSKNEKLIFAPSPDTPLSSPAGQAAVAARAAAHTAKVAAGIATDSSSGTSTPGRAGQFLQHESDGGLRKRDLDATSPISQFHAWFAEAKAVGKIAHPETCTLSTASLPSGRVSARMVYLKELDHQGFVLYSNFGTSRKGDDLFGAMGNPWAALTFWWEAQERQVRVEGKATRLTAEESQVYFDTRVRGSRVGAWASRQSAILEPKGGEDKEDDGRAQLEGWVAEAEQRFGRGADGGEDGQDDPQIPVPEFWGGLRIVPERVEFWQGRQNRLHDRFVYDRVEGEDADGKATWTVKRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ43</accession>
    <name>A0ABR3ZQ43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1237 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF0">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028846">
        <property type="entry name" value="UCP028846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185409" description="DUF1237 domain protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="60693" checksum="9BE7E243C8EDA64B" modified="2025-10-08" version="1">MAPRFLASIALALLIQQSTATAQIDQSVFEASACPDYVLYSTYPHRPLTKGPLALPFQRPHKRCRTFHSDAIETVISDVTSRMKDVDMARLFENAFPSTTDTTVKFHTNGTDGKVSDAMRAKVKAASGGAHDDGKWEGPQSFVITGDIIAEWLRDSTNQLSPYQPLAKTDPAVYNLILGAINTQSEYVIESPYCNAFQPPPIAGLHPSHNGQDDKVHPAFEPTFVFECKYELDSLAHFLALANDFHDHTGSTDYMNTRWYRALATVLRVLEQQSLSTFDPVTSHYRRNEYTFQRQTNLGTETLNLAGIGNPLNNGTGLIRSAFRPSDDATILGFFIPANAMMAVELKRTASVLAKIKGKEALAKAVAAWSQDITDGIWEHGVVKHREFGDVFAYEVDGYGSHIMMDDANYPSLLALPLMGFVPATDPTYQNTRRMLLSKGSNPYYLKGRDFKGIGGPHIGLQNAWPMSLLIQAQTSDDDEEIKGCLDFVLKSAPLGLIHESVDVNYINSYTRSWFAWANGVFAETILDLAKRKPHLIFKAPAKPYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQC2</accession>
    <name>A0ABR3ZQC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alp4</name>
        <name evidence="9" type="ORF">Sste5346_001346</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="257"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="599"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="836"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="939"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="836"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="939"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113340" checksum="53B080C87F264856" modified="2025-10-08" version="1">MSSTAARASNGAAVNGGAGSSRQTRMSHSAAAGERNSNNAAYGHNQQIPDGVHDNFHGSERSDARYRGGEGPPPPPHQHQQSHTYSSTSHKRTASGNPRPSSRATGAGGGGGATGASGLGAEAAANRAARGGTPTGGRTNISEERRTERTTITTRDTYVTRVRSPERQVPSRTATSSAASRDKPTSKSAADTRAREAPAPIAPAVPWKPEVTLLPHTTAPLASRVSIPPLSSQVPPTLQPAALGGLSLEAQEAVIMEDLLCVFMGCEGQYIRFAKGYDPNEERDRLTGPTWRILPGLDPSLQDLTASMLRTAAHYSALEAFVDVQSRETFGLVNHALCASVRKFLQDYLVLIAQLETQFLTDDAFTLHVLNIHMLPTSQMMLQLYALAHELLKKNALLDDDDETDESSDDGVDDYDKIIDRLREGGELVPGNAASKKICKGGAVLEMITKRLEAMSGDPAARALLTALLRDASRPYMVMLNEWLHHGGISDPHAEFLVKEQKSIRRELLKVDYTDEYWDRRYTLRDKDVPPQLAGVKDKVLLAGKYLNVVRECGGVDISKKVMDVPTSFDDSRFLDNINTAYAHANASLMQLLLTTHALPARLRSLKHYFFLDPSDYFSYFLELSHAELRKRNIKAVNTSKLQSLLDLVLRQPGSTVSLDPFKEDVKVEMNDTTLVQALQRVVNITGIEQGEVLQPSMLTGGGNDGASTAGGSSSGSGDADGYASLQLDYAMPFPVSLVISRKTIWRYQALFRFLLSLHHLESQLTTTWQNHMRDLPWFHRSMSKEVAVWKRRLFTLRARMLVFVQQLLYFCTAEVIEPNWQSLMSRLQTEETATAAATAAAATTTTNDDPADASAPVPLPSRTVDELMQDHVDFLDTCLKECMLTNSKLLKIHAKLMQTCFSFVSFASFLTRTMDRIDPDLAGTAPQPKDATAEQWKTFQQNTQSARPSVDPNSSTTTANDAAPTDEEMRSLVERLAKYEHLFGRNLQVLLDALNHYAATETVVLLSLCARLSTANQGTEYAGLRHEEDMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQI3</accession>
    <name>A0ABR3ZQI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="242" mass="25965" checksum="BD91AFC61B6A9450" modified="2025-10-08" version="1">MESQVNRLVDKVWDRYNQTPPGQRVMIAIGGIPGSGKTSLARAVAAGINQKHVQQAGSTDSVNDPVAMAVPMDGFHLTRAQLSAMPDPERAHARRGAEFTFDGAAFLALVNSLRAPVETTSVAVLAPSFDHAVKDPVAGSISIGPRQRIVIFEGNYVCLDKEPWRTASDAQHMDERWFVDVDFTVARKRLIKRHVAAGIAADAEAAAARADENDLVNGAEIVAGLVAAIDETIVSREDASWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQT7</accession>
    <name>A0ABR3ZQT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045085631" evidence="2">
        <location>
            <begin position="21"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="487" mass="51874" checksum="5AC659E5DEAE48FE" modified="2025-10-08" version="1">MKTAVAFAAIGFAVAGLAAPAPIPPPLTVNPDGSVSKAIPKPHPHGNEPDVAPPVDLNKAPAAEGTEEPTKVLMIPPPPTRNPDGSLSTPKVPPLLHRLMPPVENIPPAARTPVPAALRLRRNWWPFMNKPGEPGKTFADVEYEAAHIGPDGFPTSESTLAEEMEKARQANKEADEKANKKAKEPQPYFKEADASENGYFSRPFNPKYNEKHEPRGDADAAADAAAAVAKRTAPPAYKVHEEAAAAAALAKFTEKVAENEAIAAIPSDYGGDDDNLAARENAPWPIHGGYGPVNSEQDYDGPIVVKPPPKTNPVGFDHRLPHHNNPRDATWPEKGGHGPVEQQHGPVYPPGGGHGPADPPQHNRRDERWTGKISNAVVDFVAAAGPDGKHHDKPPTNIDGFDHRPIPTVVGKPPHDARDETVEAAFKDKDQALPPTANHHYSPPNTSKEPMFSEVSHAFPAEAPAEAAAEAEAPVETVAAAPAVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS02</accession>
    <name>A0ABR3ZS02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF128">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="10"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="436" mass="49489" checksum="F2CEAFE263EACC50" modified="2025-10-08" version="1">MPIGKEGNVKWVDGFRGLASSLVVLTHLSRSFDLLLFDITDNEQKASRLVQYPFIRVLFQGRIGVAVFAMVTGYVCALKPIRLSHQGQQAAAAKSMGKSALRRVPRLILPAAFATFLTWVACELGAYHTAAHCDSWWIRETGPKPQPTFWRAIRSLFNNIISTWTSGGNHIDANQWTLLPLLLGSFWVYVFMLATAYVQPRYRMMMAMAMWLYFILANDPTFGMQFFFGVFLSDVQNHPSGNKFLNDHPRIARILCPFFLILGTFVASYPEAHADRVGWSRSLHNVLAAILPNNASSMYPRFASGLGVQLMAIGLHFSPKMRDVLSNRAFLWLGKQSFAVYLLHGPLLRSVLAWMLYGFKTTPDTLDAEGKPEHHYTKFPGMMHLYVSLMMWIPLNYFAAHLWTTYVDPYCGKLTEKFVKYVINEETEKPQPLLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS31</accession>
    <name>A0ABR3ZS31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored serine-threonine rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011824" description="GPI anchored serine-threonine rich protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="17178" checksum="D0ED37BB55E6C8CA" modified="2025-10-08" version="1">MQFLTVAALLASAVSVSAAATTSATAPVATSACAAQNILDACIETETNLLDSCGTNDWDCKCNAYGNMVTCYNNCPNDQTVSTVKGQQQIFCGYASQYPSSTTAAAKKTGNTATTATKATGTNSASGSESSGSATSGTAAGTATAATETNSGADLAFKSGSMLFAVAGMVAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS49</accession>
    <name>A0ABR3ZS49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="194" mass="21525" checksum="C57E0DEB910522FE" modified="2025-10-08" version="1">MSSFAHFFSRGQLAARSDGESGNEHTITAMIILLAIVFSGLLLTSTLVMLRRIKRRQQMLAMGLPQYNDKAGAGNGNPHGLTIQTTNANGRSSTLIFGRDGQPMLANPQSPPYSPDNVPEIRITFPDEHDEMGRRKSGRVVVVRVGEHNAVGMEPVAEQEEQLPAYEKDSKSQFYSIDMDQIGGLKEKQYRDYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZVT1</accession>
    <name>A0ABR3ZVT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_000196</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF24">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="306"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1903568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="597" mass="66364" checksum="FAEC294B9E9059DA" modified="2025-10-08" version="1">MAAVNGTVAATNTTGAAAAQNATTTAASSAFNPALENKLLANYLMLIVGSVAFAMFIHRAVYAMLRHVRTVTSLQNDTQRYYARPDPQMSWIKRNVVYAPIFHKRHNREIQMSSAVNIGTLPSRLQLVFLAAYFGTNVAFCLIDIQLHSNFSTAAAQLRNRSGVLSVVNMVPLFLMAGRNNPLIPLLGMSFDTFNLLHRWFGRIAILEALMHTLAFLIPIAIAKDWAAAFQTAISVKYIMFGLIGVIAFLFIGIQAMSPLRHAFYETFKIMHILAAAVAVMGVWYHLKLKNLPQIVYLYAVVALWAFDRLARVLRVFYHNVGQGGTKTLVEALPGNACRVTVTMARSWNFKPGQHAYLYFPSVGLWQSHPFSVAWSEEAESLDTEKLAMNRQDVLAMRKTSMSFVIRGRTGMTAKLYKKAAASPDGRYATNCLVEGPYGGLHQMHSYGTVMLFAGGVGVTQAVPHVRDLVVGYANGTVAARKIVLVWIIQSPEHLEWIRPWMTEILAMDKRRDVLRIMLFVSRPRSTKEIHSPSATVQMFPGRPNIDTLLGIEMENQVGTVGVSVCGPGALSDEVRRAVRQRQYQGSIEFVEEAFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG83</accession>
    <name>A0ABR3YG83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Small oligopeptide transporter, OPT family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_010289</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000127">
        <property type="protein sequence ID" value="KAL1887331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="601"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="717"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="746"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="811" mass="91560" checksum="C55A309BA75DFAC9" modified="2025-10-08" version="1">MGLLNFRKRHEQEDALPEVLDASGSPGVGESPSAEAVGATSGVEALNALKHFERMHHLDPNLPIEELNDVDNAINTGNVEKGLAVEQGIIEDNSPYPEVRASVRNYDVDMPANTIRAWTIGLILCTVGSGVNMLFSLRNPSVSVTTYVIQLIAYPIGLLWDLVFPDRVWNLFGLKFNLRPGKFNFKEHVIIVVMSNAAYGGGALYATDVIIAQQVWYKQYFGWGWQILFGITTLCTGYGIAGLSRRFLVWPAAMIWPSDLVNAALFYTLHDHSASDPAKTNGWSMGRYRWFMIVFGGSFVWYWFPGWIFQGLSWFCWITWIWPNSKIVNQIFGGLSGYGLFPLSFDWTIISGYLLSPLIPPFYAIANMMFGIITFFVIISAGLHFTNTWYGAHLPVQSSSAFDNTGAVYNVTRILTNFQFDEKKYFEYSPLYLSTQFALSYGLSFAAVAAVIVHVFLYHGSEIWSQFKLARHQEDDVHMRLMKKYRDAEDWWYGALFVIMIGISFAVVCAWDTGFPWWGYVVCMILPLVWTIPIGIIQAITNTQLGLNVLTEFIVGYMLPGRPLAMMMFKNYGYLCMSQALYFAQDLKLGHYMKVPPRTMFASQLVASLWSAIVQIAVMNWALGSIDGVCTDEQANSYTCANAKVFYTASVIWGAIGPRRIFSGQALYANLQYFWLVGAVAPIVTWLLARRFPKSFWRYVNTPLIFGGSGWLPPATVYIYLCWGAVGTFFNWFVRRRWNGWWLQYNYVTSAALDSGLIVSTLIIFFTLYLTLAEAPNWFGNVAVYETADFTKSAIQQPIPDGTTFGPTSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGL1</accession>
    <name>A0ABR3YGL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045674529" evidence="1">
        <location>
            <begin position="22"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="240" mass="25497" checksum="F7D3D676077D31C3" modified="2025-10-08" version="1">MAPSALVALVVSGLPFLAAAAADNMLTLFGPASLDNEVSSTFLACVNATGVDYGVFVEDAGGAVVVPMDQRQLDVFTTDAPLMQCIEASNDAIYVSAESTAEISAVEKGAVSLDAATFEWLVSSGVTGKQAVGTRPAATPLTSKRGADAADITQTYSAYLDTTGKHCTDHDHHTYQEKECHGVRQQYKSSQFENTHGGSLHMEIWPHHDCKKGDSRAFVITGLTVGTCNGRDTYSWNGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGM7</accession>
    <name>A0ABR3YGM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_010183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="84" mass="8949" checksum="F75707C5DA9CFA79" modified="2025-10-08" version="1">MRTLTDGPNGTLGVHLDGSTRAARFPAAVNIAATFDGNLDEHIGEALAKKPQPRALVVFWHPPSVSNAILLVAGISRRIARIHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH79</accession>
    <name>A0ABR3YH79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010372</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000137">
        <property type="protein sequence ID" value="KAL1887197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="205"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="400" mass="46126" checksum="3CEA27426C1EAE8A" modified="2025-10-08" version="1">MAPAAPFSPPAANLPGKPFVPEWVPPPITKETHNFAKLQSVDLSLLDSEDPAVVEKLVQQVKKAIRDDGFIFLENYGISLEQLHRQFAIAQYLYKNISEEDKRRLLFSPETGKWSGYKHPYGFKRHQGPPDGIEQFNWYKPDWEDINRTPSCLHPFMDEIEAFCNYLTQSVNRRLLTLFSRVLELPDDWLWDNIQSHGSPTGEGYFRHALFRPVKRETEEASKGLRMHGHTDFGLTTLLFSVPISCLQIWGEDEQWYYVPYKPGALVINIGDTLEIVSGGHFRATRHRVYKPPVDQLQEERLSLVLFNSSVGDLRMQPALESPLIQREGCVEEQGIYREFKKRTAEADPPTNREWREIQIATCTDPTDTEHNRIGVHQTVINGKLMHQREYMGMKVILPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHT4</accession>
    <name>A0ABR3YHT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitofusin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FZO1</name>
        <name evidence="9" type="ORF">Sste5346_010039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF0">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="8">
        <location>
            <begin position="306"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="523"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="537"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="560"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="950" mass="102849" checksum="3314916EF730EC9E" modified="2025-10-08" version="1">MSPKTRPNKGKAPSNKPAIVGEHDAGDSSNSNSNDNGKDSGNDAAPQPTAPGYMTVGTGSGSEHMSNLKHLIDKDSGYGGSTVGGDDDIRSAVNSSFAWDSAVQDNQHMYPAASSSSAADFEASRRLQAGAVHQMWYNQHRVALGKSITQVVELLKGLQKTNMSWPAHYPTVQRISATAPLPPPSPTRPGLQHAHTTVGDLIATSTPPPEAQPDRGPLRRSYTALEDNAAAESSKTAETRPASTEPRLVTPQIAQEFSVLKLDLKLGGMHQAELVHSLEKASIASLLDEKIRSSLRHLESLRDRIEDISSKVLITGDLNAGKSTFCNALLRRKILPEDQQPCTSIFCEVLDASENSGVEEVHAVHMDVIYNRNDESTYDVFSLQELEKIVTDNTTYMQCKVYVKDERAIDESLLSNGIVDIALIDAPGLNSDTTKTTAVFARQEEIDVVVFVVSAANHFTLTATEFIRAAAAEKAYFFFVVNGFDVIRDQERCKKMILDQVSGLSPQTHKEASELVHFVSSNAIPIAPPPGPPGGPGGPVNGGSGSSSGGGGGGDDDDDANGKGKGKEKLRNFESMEQSLRRFVLEKRAHSKLAPAKNYLLNILNDVNALATVNTEVAQAEITRVANELNEIEPLLENNKKAKTEVATEAEQIIEKTCKDVYDHSRAVIGFSIAHAGDENLGVPYPGLLSAFQYAEDIKQAMFSQISASVAECEESARVKAGGGVNTLKQLGILHLGDDFTDLNFRPEFMFRRRRDELARRLDVPTEIIDFVDLSMILQRQEKVAGTGMALTVATALGTRMIGGQGWMDHALSAVKLMGSNGSRRLLVPGLILAAIAATGYILSQIPKSLPHRLSHKISSRLAEIDYVHYNSTRIAGTVRKVLRYPADSIRDGLNRSVDQLGTRREDTLKIKAESEVALKYFGNLVVDSARQRSVVRSLDLDTPPPGAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHV2</accession>
    <name>A0ABR3YHV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009909</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF17">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="446"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="631"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="640"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="770" mass="88120" checksum="ED4CF9CAC72B0918" modified="2025-10-08" version="1">MLAARAAPRRLLGAVPRLATPTVTRPQWHRLPPSPPLFVCRQCRFETTTTEAAATAEKPKVKRKRRTKAEMAAAAEAEAAAAVDTEKPKVKRTRKKKVTEDAEATDDEPSTRPKRGRKTNAEKEAEAREARRKKDADEAPTISMKYSTNANAPPRHALQKSSRIAEELHATGLWNYGRWSRTDLTAATDAIDTEARPKKRKVKGDRNRVNIVSESLCDDTLKYIEKSLLPRHKGCDILDIYPGVGLWSRKLHDLLQPRSHILLEPDEDLYQPWLQPLLDRPNVKVIPKSGIIWRELSNILTPEHLPHQVERPLQETPQRNDTLLVTANLAFFPKRKFGQFASLSQLVLYQFINSIRASSLFNKYGLVRMLVWVESSDRHGLLARSIQRRRRMAMDGEMATEWITEIAGPDDFSPWFIRDSKLDMASTHRTLARMEKAGISIPAGRAPMNVHEATKTSRPGPKHKKPPPERLDEPPEFERPYREELYDLECRYEDGEFEEKSANHRRMLQLQYRSNREAKVAETINDLLLRREKFADEHDIHATRAANIRLREQKWTDEFDALSDNDRQEYSLYKDNLHIFKQDPPVLTWDRRAVEPLVAKRDEFYPNAPCALLDIQPKAVHPLLRPTRARELQTTAKPASDGSGSTESTSTTEDIPSPWTPDYAHSADFFDLIIRGMLNQSADPVRKSIEAVWPGAAEGVLKYCPSLYDRRSGGHPVGGPYSELTARSLNEKQWIEILDAWMRWPFRPTLSQLARRISEEPETEDNEGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIG1</accession>
    <name>A0ABR3YIG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF15">
        <property type="entry name" value="HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="53"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="36229" checksum="9B8B41B03387EE84" modified="2025-10-08" version="1">MDVQHHIIKDFAFTDGTVLPSISVAYTVLNPTTAKTALVVTCFRGRLQNTCTFAKGALKDHRTIVVALLGNGESSSPSNTPGFPQSTLDYRDCVRAQHDILQNALKIQSLDVVVGFSMGGQTTYHWLLMYPEMVQRAVIICSSARTSGHNVQFLEGPRFALENSVDYVPVAKRDGEMSTATRGIQAFGKAYSAWLTSAEWFQEEGFRSLGFDSRVTWDAATTGVNYSGWDADDLLAMLGMWQRGDVTKIEDGTSKTLFDVLGNIKVPVLLMPCETDQYFRPFVSKREAEVIAQATLKVIPSIWGHLAGSGANPVDTQWMDGQIRVFLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJU1</accession>
    <name>A0ABR3YJU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="159" mass="17675" checksum="690F03BB07B2917D" modified="2025-10-08" version="1">MDRLTDLIGLLPALVEDLHAVPSGPVICLVDKVVLTPVMKLRFDTLVAKLQSWRNEIVPGLRMEELFLSQRTRASNKRKTDPEVEGSSSTRPQLQASISTSTPQKMSVVLKHFHIRLELMGDLGNGDWVKVAHRKPARSTFRTGGSKGPDKWHTAAAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJU7</accession>
    <name>A0ABR3YJU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000095">
        <property type="protein sequence ID" value="KAL1888305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972419" description="WSC domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="183"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="379"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="478" mass="50007" checksum="540F0BD11ECA73EB" modified="2025-10-08" version="1">MKTTALAALTGLVLPLVSTVAAQGYFGGDEYDVCGDDYQFRYIGCYDGELINDAGSTFVLNIGTYIPSDPQLNYANPFPGYVPNTNYNSTVAPYSCAQACRGYGYGYSAMASNECYCSPLPPASDATASNTCTEPCWGDASQTCGGARTGADTVGAAQVYGDPSFASPVFVGSNMAPGSLDSYYQYLGCYYQPNFGPGAAQGNGVIKSCQASYTECYTHCSAYGYPLAAVGYSPSGTQMAQCSLEEPVSCLCGTSFGEGSYRVDDTKAPYESLCAVDCATGLACDSTTQTCCGSNDYYPVYINPELTGCYQPQIPGYGVLSGSTLTDYTCAAPPDSDLIGGPKVLPNGVEYFEGNDYINTVVANHPVFVVSPEDAPYDNYYIIGCCSDCSTGEVFSSTGSIRASYGAENGLHVCAQQCAPLGYPYFAVGGGGVDCYCGTTLSSAATPRDMAECNQPCYSNNEQNCGGAPGPEPGMRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK72</accession>
    <name>A0ABR3YK72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Concanavalin A-like lectin/glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049792" description="Concanavalin A-like lectin/glucanase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="30360" checksum="CB5D146ED7946638" modified="2025-10-08" version="1">MKSFFVSLATALAAGVGHAAPAARSTFAAGELELLSPDFVRHLHQADVVSTPPSTNGTTWTNSTTTPHAGSHNSNTTTCGAFQSAAADAPMYIAATAVFVVPKVAARPAFNWTRDPAVTPRIAVSAGVDGFACPEAVRAGIYATVFQNGTQQHVPFVEFSGKVYAVRIASVAPGEGVRVRVSIVQDDVVNINWSNLNRTDQFFDKDIPTASSMCGQSVSWLVEDLVPFKAGPGDFFAAFDPVHFSVLEGDRMDGNTTKFDATTANFTTEQALCKVDETGTEMTVTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL66</accession>
    <name>A0ABR3YL66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neutral ceramidase</fullName>
            <ecNumber evidence="3">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the neutral ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="entry name" value="Neutral/alkaline non-lysosomal ceramidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670:SF20">
        <property type="entry name" value="NEUTRAL CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="6">
        <location>
            <begin position="110"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase C-terminal" evidence="7">
        <location>
            <begin position="641"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="803" mass="85688" checksum="D3725C34333A99C5" modified="2025-10-08" version="1">MAPYRHAYGPVQNEVHDEEKEFKDDDNEALPQPPHRPPPRRSIIVAIAAVSFFILAIFAVWQIGKPSFSAGSHSSTSSPAADASAEKAAFNGGHNELPPLARSTPTGDKYLIGVGKADITGPVVELNFAGYASLAQTGTGLRQRIYARAFIIGDVSNPDDRFVYLILDAQSGDAAVRLGILEGVAALGSDYSVYGSSNIAVTGTHQHSGPGAWFNYLLPQVTSLGFSQQSYQALVTGAVLAIQRAHASLTEGYLDVGTTNITDGNLSRSLYAYMANPAAERAQYVGATDGSTDTTMTLVRLQRASDLKNIGVLSWFPVHGTSMLENNTHVTGDNKGVAAYLFEKDMASDPNAAPGFVAGFSQANVGDTTPNVLGAYCDDGSGQMCSYENSTCADGKSESCHGRGPEFQKLDLGVSSCYEIGRRQYAGALDIYNSLTTSSTPVVGTSVKSFHFYQDMSFFQFQLPNGTAVQTCPAALGYSFAAGTTDGPGAFDFTQADSGNPDANPLWAVVADLLRTPTAQQTACQHPKPVLLDVGEMSEPYAWSPNIVDMQALRVGQLLIIISPSEATTMSGRRWRNAVRDEAANTFLKGGADPVVVLGGPANVYAHYCATPEEYGIQRYEGASTLYGPWELPAYINLTVSNMKYLAPDATGTPPVGPTPPDNRKTSLSFISPVVFDAAPIGKSFGQVTTQPSAAYTKGQVINATFVGANPRNNLRLEGTFAAVEQLNSAGDWEQVRSDEDWSLVYTWERTNTVLGYSSVIISWESETTAASGTYRIRYYGDSKPLIGSISAFNGASNTFTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM40</accession>
    <name>A0ABR3YM40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS5</name>
        <name evidence="6" type="ORF">Sste5346_009240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="67"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="212" mass="23696" checksum="D53127E70BB2E60D" modified="2025-10-08" version="1">MSDAEIEVETVSYNILPKEVTNEIGTVKLFNKWSYDDVEIRDISLTDYIQIRSPVYIPHSAGRFAVKRFRKANCPIIERLTNSLMMHGRNNGKKLMAVRIVAHAFEIIHLMTDQNPIQIAVDAIVNCGPREDSTRIGSAGTVRRQAVDVSPLRRVNQAIALLTTGAREASFRNVKSIAECLAEELINAAKGSSNSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YND4</accession>
    <name>A0ABR3YND4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NuA3 HAT complex component NTO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15670">
        <property type="entry name" value="ePHD_BRPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="519"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="573"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="178"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="485"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="991"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1130"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1216"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1333"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1246"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1333"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1343"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1364"/>
            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1376" mass="147188" checksum="E9AD3311D824F5AC" modified="2025-10-08" version="1">MAAAPSTPRRTSTGRRRGRPPGSTNAARAAQMAVASSEPPPKRRKYIPGGPGGGGRFVDEDGNVTYVVRGAPKASTGGGGGGGSSSAVAPRRQPKVRALKPATSSPILPRRERSTRTRIAVSRYEPDDEEQFSSAAAVAAAVVQSEGYKPREERGWEEFHPNLDIETTFMVFRSEDVDGTARRQSATATPTAGLSFSGVSPFADGGTSTTSHDAGTTATPTIGGVTDTNGVNGGGLPNGDTNTAATSFSTDASQQDLAATAAGTVSPSAAPGILPETPLRRRIGRPPRDSIGLGLVSYGYSTTPKTPKVLPIHNQTPKEKLDLKLPSYRKTDRILLFEGKTFGRYVDKSMMNVGYQESDIYVRPDRYLIKASDANAEEEIDAYHAAADKDADSTNSTNGNNGSVSSYLPNTYGVPGSSVSLVLAGGGAGSNGGVGRVEYDMDEQDDMWLVKHNAQRKVAGADPITREIFEITITKIEKEWHALEKRIPKPNPKPPQTHRPRSSSAAAVNGETQGGEEQDSKCAICDDGDCENTNAIVFCDGCDLAVHQDCYGVPFIPEGQWLCRKCQLIGRGIPTCIFCPNTDGAFKQTNSSKWAHMLCAMWIPETSLGNTTFMEPVMDVDKVPKTRWRLSCYICRQKMGACIQCGNKACYQAFHVTCARRARLYLKMKNSQGNLAILDNSMILKAFCDRHCPADYAKENNVHQATREAKRHYKRTMRGRIWADSRASALQMAATTHAMVEHPVDESQMTGARITAAMGAAAAAANPGGDDVAMTDAGSSAGDKKKGAVAKPMWRLPSGAPVIPQAVFDIVETALQRFMLRRRREFVSEACRYWTLKREARRGAALLKRLQLQMETFTSMELTRRNFATMGPSGQARLERRIEFAESLLQDLDRLRGITGDLVDREREKLELVNLEQDFVDTCYFPIHQLLAPVIEKATSYDKDKDVFRTAFAGLQAKLNARYYTNTLAFVQDLANMVRYAINEALQVNDKTTPPADEASSSELANGNGEEATAPAVTATPKLTGAAALTEARDRKRIAKRILKAIQPMLEAAIRAEADITRVSLEPLQKELEQLLEASVELQPASGPVQAPASASVAPAEDTVMLDGTEDAGSVGASGQIVVASSATVNGTAEDTVDDNNKATDGEDMMDVDPATPRASTRNKPISIEITTPRSSNLLASGAAALGSLQKATVVECKEADGVDATHVTAAAPSADGGLLSANGGPLTPPQSHNGSLPGGGGSVAIISQDSQRPQTSVDTLHDGGVLWYLNSFGLEGTTAVEEQWSSGRDAVRMLSEDLTDMDDEELNGLGFDVEDNTITAAAEEAKEVAAAAASSLAPAPSTRSQNLTVTTPKRRGAAGATTPHRKGVRSSARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNW9</accession>
    <name>A0ABR3YNW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Catabolic 3-dehydroquinase</fullName>
            <shortName evidence="2">cDHQase</shortName>
            <ecNumber evidence="2">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">3-dehydroquinate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">qutE</name>
        <name evidence="3" type="ORF">Sste5346_008816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aromatic compound metabolism; 3,4-dihydroxybenzoate biosynthesis; 3,4-dihydroxybenzoate from 3-dehydroquinate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homododecamer. Adopts a ring-like structure, composed of an arrangement of two hexameric rings stacked on top of one another.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="entry name" value="Dehydroquinase, class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003804">
        <property type="entry name" value="PRK05395.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003805">
        <property type="entry name" value="PRK05395.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003806">
        <property type="entry name" value="PRK05395.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003807">
        <property type="entry name" value="PRK05395.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="CATABOLIC 3-DEHYDROQUINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272:SF3">
        <property type="entry name" value="CATABOLIC 3-DEHYDROQUINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="Type II 3-dehydroquinate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="118"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="165" mass="17839" checksum="769757CDD5A02428" modified="2025-10-08" version="1">MSRRILLINGANLNMLGTREPEIYGSTTLNDVVVAAQAQAKELGVELEVFQSNHEGAIVDRIQEAGGFGHLVTTPVAGDASRKRVDAIIINPGGFTHTSVVIRDALLGVSIPFIELHVSQVHSREAWRHHSYFHDKASAVIAGLGAHGYTVAIEYAAKHLKIKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPC6</accession>
    <name>A0ABR3YPC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="447" mass="49252" checksum="6B286F745FE081F9" modified="2025-10-08" version="1">MPFNQATDLQPGEARPQYDPTWSTSERYWTNFLYAELNKDALTRNLYNIMRKPYTEGTQVLPGVLSDLLFFEYVAVSVYYNGYDPLKWTNICPHMVLVTNKTFPGYSILDHIEELPEPLWPRFNRAIDPGLTVAYLPTGEYVPIPNNSPASNSESPMLDATIHPAFLSGIGSYIPFDGMLTPPRGGCGAYAILGQPTDVVDLVSPSPQPSPPVQPSLPVHGLQVSLPQKTQVSKTQLSLSGAVDRWNGQNAATVPPWAIPGPNSSAQVGLQGLYIPCTKAAEAIVDLANAGQIHFATDRMQGHQITSGSVIVFREGKIKRWTDGHNWTQSRKGKGKDAQGYMVYRETNGSSKQSTGSQKVTTSVPVTKENIEETLHMTAEELDSCDIPPKEIAKLLLCNYTFDTDLKYGGLVKSSMKVEKPDGSVYRVMSFYRVLDVCNGTVRPFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPD1</accession>
    <name>A0ABR3YPD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028322">
        <property type="entry name" value="PNRC-like_rgn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15365">
        <property type="entry name" value="PNRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="51368" checksum="85615AAA9FF58DB5" modified="2025-10-08" version="1">MPDPPPAPAPAQAKQTSNRRRRPNRKNYASENDVAKADPGFQPDFVPRNKKNGGGGGGGPSTPQKAQKNGMPSKSPAPGTQAASGKAGNNRNNRNQQNNNNNNPTSPPAKAGRRTPPQTAGPKPIGATASVAAFAGATFHASPAPSSLPVPSFFTKTNSPGTPSARPLSGLSQQPSPPASDTEVPSSTATKPVGASSAGGRNPLFPTGGVSIPPPRDESPLDLLFRADRAEKERNRRASSANLYGAPVGPFSPPLQSQSMADNANSNTFPRDFAQQQQQQQSTRRPGPTLRTSSSGISAAELDGTPGQPMGPAFATPFQDRIRAARPVEAKGTSGAGAPSGFRDLAAGSAPSPFAGGPYNQQPPPPAANIDDRSEALKRYLFSKTAGSTAGSTASPSAHPTASAPTTPTRYPGPPGAVQQPPMYGGTPYQNKYSMSPANGTPNHHQGYPNGQPQATPNRPHGGNNGGSSNIAAMEDSLRQILKLGSPFGNGAPSPGLSRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPF1</accession>
    <name>A0ABR3YPF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate transporter (Pho88)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PHO88</name>
        <name evidence="3" type="ORF">Sste5346_008380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="195" mass="21176" checksum="8A3CBEDFAEE481EA" modified="2025-10-08" version="1">MAGLTSLSPQVTNLVIILGMMQVSKRIPFEDPQTLQLVRIGYAASNAIILAIYLYIQAKINSKKDLTTLKYVEPAPMGSSEEGKLVTTTVHAYDKSQLKQLMRSQMMGVGMMAFMHLYMKYTNPLLIQSIIPLKSALESNLAKIYVFGQPAVGELKRPFKAGGGLMSGLQSGPAQSDKKAVEAAERAGHGGVKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPT7</accession>
    <name>A0ABR3YPT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008527</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="71"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="467"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="992" mass="108209" checksum="D6727CAA40F3C910" modified="2025-10-08" version="1">MTNTNQDANAVVDIEKQPSHVVDTTIISSPDTSTPTTEDDTAIESIPGDLQTTSTNGDIYDRFGRGRKRLFVAILSLCAIVSPISSTGSLTAVPSIAADFHTTGSVVNIGNALYITMMGLSAFVWGALSTVTGRRPVVCTSIVSFLAFSIATAVAPNLTAFFIFRMLTGFGGTGLLIAGSGCIGDLYRPTERATALGWFQSGVLIGPAVGPVLGGVLVTYTSSWRDIFWLQSGMAGLAAVLAVFLLPETIHQHAWKDMPRKKERLCSVVVALNPVRMLALFQNLNVVLVALASSSLVWNMYSYLTPIVYVINPRVGLTTPLQAGLLYLAPGSGYLLGTVFGGRWADYTVKKWIRKRGYRLPEDRLRSMVPWMGVGVPALVVMFVQGFCQLMVFPALNSYCLDILPARSAEVIADVMDGRKYKSRGQPPCDACRKRRICCVRLPGTVDCALCQTRQVHCTYKSVPVPKHGRGPSKRRAAVAAAGTARGTTATNTNGTTTAAGSAGMSPSTNSATLTEPTRWITQFLGLSGDQDPFVLRHCTFDADCYKRLDWACLRVSGGNGSSDIPAQFAVVPDTHLDARPAYYPSVDTWNSLMGGPERQKLLNVYAQTIHASFPLLDPQQLDPDTLTSHRDSRSLLLASMCALAAPFARTACTMAHRQALYRYVFEALPIERRHPRLEVIEAALVFIQRHASIHRAPTTPGLWSEVGAVVGMCHELGLHVDPSGWHITAAHRNRRIRLWWATYILATFCSLGLGRPSYIHEGDWCVPMLGKEHFTTSTTSESIGSVHSGGSSGSPNTPGSTAGETLNEIGQTNFIVMAHLATLLARLLQSLYSLASVERLRYAPPAEVHLLFLTFQQQLLQLRAHHIDCRPSMAGAFLDSSGFVRLAYHAVEIALCRATLRHLDASFVYYAGVRQYAREAVESVVTLLRTLQINQMRAYWWNPMSQIHFSLAGSFLFYLLLSSTDEDEIDYWTDTTSSNTDGSTGNCKWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ33</accession>
    <name>A0ABR3YQ33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3 11">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ndk1</name>
        <name evidence="13" type="ORF">Sste5346_008488</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 11"/>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="12">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="151" mass="16675" checksum="7B9EE30188CAA800" modified="2025-10-08" version="1">MATEQTFIAIKPDGVQRGLVGPIIQRFEQRGYKLAAIKLVSPSKEHLEAHYADLKDKPFFPSLISYMLSGPIVAMVWEGLDAVKTGRVLLGATNPLASQPGTIRGDFAIVTGRNVCHGSDSVENAKKEIALWFKEGDVISYKSSQHDWIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQA1</accession>
    <name>A0ABR3YQA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trehalose-6-P synthase/phosphatase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TPS3</name>
        <name evidence="4" type="ORF">Sste5346_008195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF15">
        <property type="entry name" value="TREHALOSE SYNTHASE COMPLEX REGULATORY SUBUNIT TPS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="951" mass="106684" checksum="0013C28D58710188" modified="2025-10-08" version="1">MTVFIASLFLPKTVHFDLPGTPPLVGQSPALDKEPKKKKKKPTASVVAAPSGPSRATTTVEEAPSLFKPQSDITPPDTPTEDTNIDPFANEDGVRIANLPSVLTNSLDVAAAAAAAVAKSASKSAAPADRGSPAWGARRDQPKSRANSPPPALLNGDPHLNEKAKEMRRQGISQPRTYLRSDSHDRIFSSANWHIVNADQGNGGLRNAADAAAREGKLGDYTWVGTLGMPTDALEGTQQKEDINDRLAAEHDMLTVWCADKDFDGHYVHFCKQILWPVFHYQIPDNPRSKAYEDHSWKYYVNVNQAFADLIIKNWKRGDVIWIHDYHLLLVPGMIRQKLPDAKIGFFLHVAFPSSEIFRCLAVRKELLDGMLGANLVGFQIHEYTRHFLQTVTRLLNAEATSDGIQLEDRFIDVINMPIGIDPVALDEHREESEVMSWLNILREKYEGKKLIVARDKLDHIRGVRQKLLSYELFLNMNPEWRGKVVLIQVALSTSERNELDATVSDIVTRVNSLWANLAYQPVVYLKQDIDYPQYLALLTDADALMITSQREGMNLTSHEYVFCQDGKHFEKKHGSLILSEFTGTSELFNGAELAINPWDYRACADAIKQALEMGVEEKSSRWSKLYEAVRHHTGSHWFSEFLSRLDHVYDEQHRRDQTSVPRLSMQTLISQYKRTSRRLFILDYEGTLVSWGPVNKIIPVSPQRTLDVLRDLLLDDRNTVYVMSGRSEKELDRLFRQVPNVGLIAENGCFLKHANCGSGANSANGNTNPWIEMADPEQIRTWKESVKQILQYYKERTPGAEIEDRRCSLIFHYKSAEDYESATRLAADCASHINDSCEEQRVHAIPLDGSILVEPIDWTKGTAAEKIHEELRKELSTDDSSSNKLDFLMVVGDGRDDDKVFKWANQLGDDGTVKEVVTVSLGSRSTEAAATMTQGVSGVLVALSKLANVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK3</accession>
    <name>A0ABR3YQK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460593" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="21502" checksum="9D765A0D99AFD7BE" modified="2025-10-08" version="1">MKSFASLSLFGLLAGLVTAVPTPAEIAPRCGTTYYPTILQQLSESSPNTVGANTAASNGDFHVAQTVVNGGAPYGRIYQFVGFQGIAAGSYGCQLSITFPAGYPITSSVGNVAGASPQLNVTTVLRSNPGAIYYPNGFTFNSFPAQLAPGQGLFGTVSAAAGTTVVINSESCDSNLAFVFSIATWTGQSANVEFAEKKSPLAGVYLTANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQS3</accession>
    <name>A0ABR3YQS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047090365" description="Lipase 1" evidence="2">
        <location>
            <begin position="32"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="53613" checksum="B787BC11FB1A2894" modified="2025-10-08" version="1">MAHCRSGGGFGLRCLLSSLLLVSAFASTATAGFSVHHSPITGEVVKFFGERPSTDNSTVKSNSTTTARYLPPPSKDAWYVPPAGWESAKPGAVLRTRAHAYPTLNIRNAIDTFQVLYRTTDSRNNASWSVGTVFIPKSHANCVLNTTSPAYNASACAHGLVTYEVPSDSADPDAAPSYLLQMREPYGEMRDMLARGWFVLVPDYEGPGASFCAGVQAGHATLDATRAVLSLAGPQLGLRMDRIKVGLWGYSGGAFAAEFAAELAEFYAPELKIDASVIGGSSPNLTTVDERMNAKDTAGLVVTSILGITVQQPSAREFLLNQLHPTGPYNKTAFMNATTMTGADALDAYSGQNVFDYFVNGREDWTNHAMQDVINEDAVMGLHGVPRMPSFYYKAANDEMSPVNETAEIVESFCKQGANILFHRNTLGGHNDELWSGRLRALDYLSMMLDGVEVTGSNLTIPATGCATVDVTIPLDPLYLLPDWWWTEGPGAGLGLAGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQS5</accession>
    <name>A0ABR3YQS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="153" mass="17333" checksum="45B3D5ADA20BBB32" modified="2025-10-08" version="1">MLSLDTPGSPERAAALADIHAVLHGYAFMARDKALFAEMAKFFWPDGWFRFPSGHAVRPTDINLIVQGDEAEYIRHHITTINVQFTSDNEAHVNAQFFATTHLSFYDHWGAWVDDFRRDANGEWRIADRTIVLEGTAPGGWGEAKLGKFVKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR89</accession>
    <name>A0ABR3YR89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein HRI1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11692">
        <property type="entry name" value="HRI1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.320">
        <property type="entry name" value="Protein HRI1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031818">
        <property type="entry name" value="Hri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038744">
        <property type="entry name" value="Hri1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043047">
        <property type="entry name" value="Hri1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16815">
        <property type="entry name" value="HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="220" mass="24339" checksum="011CCD80F99FA761" modified="2025-10-08" version="1">MPARLSTRISIRWGDDEASEPTETLVMSVGGYFMDLRVVKADNSVDWAFAGTRDIVARQPKLHCRWHHVIDSHNTFAPDEGFFTDLPNGDSLETGSMACMEKGGAVTDYEEIWRALPTEGLRAWILKREDAETNNITFLGRVGSEFFAMVQKRGGGPLTVQREVLEEDKWVVKYQSGGAALPSLVNSGLSALTNEVTWKQGDEADVQGEKYTVCSTESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRG1</accession>
    <name>A0ABR3YRG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="757"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="873"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="938"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1266"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1304"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1383"/>
            <end position="1408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1451" mass="154981" checksum="477157A71AAD8C92" modified="2025-10-08" version="1">MNRFRTKKKVKEEQAASTGRASSDEQHSFMGFRRKAKAPEEEKKQIDITNVLPPSDDFRTSLLMTGLSARFSMLREQDDPNTKIGKALDDSVLYPKRQSRLMDFSGGFRGLDDIAEVESIRAHAPFMRTNSFASDTDSLQNDSIMNRTRPTDGNNLFGGRQKIYRIPAGGTSSKNVSEGGMGGRALYENDVALSAFQKLRQEKKEQFLDYEDVSQYANGPSTNNGNTLLSADVYDPSSSSYQRSESPSPIEYNLRRETSSTTSSAARNSTAATSVTSQPGLSSTKEWQSPQLQSSAQPASSNGAVASSGIGVERMPTSRIRRLYEQGLNQDLHEQQNSALSRIDTLTGKRLLRTKTPDLSAAPSPTSSFSFPDRVVPVAGGTVMSTLERLERRQVLSKASAPNLRSMSPPMSGSSIGSVAAPSSNDSAGLKVLVGAPESKNAFPRSPPLSPPVSESSGEHTMLSIQPNDVGKATALGMFQKPTLPYDESRFAERQLQLQQGRETPTERTRPSLDVAPAASSASPVPPAPRPVSVTSDEDSAKAQKTFLFEDDDDDEDDTDAAVKSVQSSTPRPQVLLQRPSDADHPAFRQSAMPPPLSPSRSTENFTASAPDMPEPPIIATEVTLGEETDGPPVDSPTLGPGGGLSGMVLQHLRSTSNASSVYSTAPQTNDFEPPHLQTSITSGSLDLKIGQPWDDQNWTASVYSSVSGVDNNDKKEAEAEPKLPALPQEPAQKIPTQRPPIPEPPKNMFTDVETTRAPSLRSVSSRSRITSVADSNRSSNNLDGEHEDDDFASQLANARKRVQERLTTYVESDSSRNTSPLLAPTELATQPPPIKSNPLGILRAKSSRGSLLERSRDVSQTKSTRKLGLGATTMSTAPSPSKQSFEDMSSPVPTPPISSASAAVNDGFSLEALKEEREEKPRPSQDGYFGRMPASRSASANQSPAIASSAASVPRSSTDTDVDDADEETEGGAGAGNDDNNMHPGLRAFRNARRQLQKRKELETLARHQADAARGADSGPEAAFADQQSPPRRERRPTVSSNPTSRERKPPPVYYQQRDPSLESRSSSNGNGGRSRSGSRTSGQPERDRSGSEASNGGGYTRHALPRIRANQNQNGAGYDDYQHNQPGLNSNNHLGPPTRQGMPMRSPGLPGTDIRRSPHMPPQAYPGSTGNSPSMNNLSVQTAMGGRSPSGFSASDQPSPISPLGSAGLPSSPYFAGSANASGPSTPTTNGPRMQQQRPGMPQHQAPPSSGPGYSTTNSSLNESMKKSVRKNEISEPTFLMSTSRVPTVSLQQSTSAPEMEANGTNGNGSRSRSGSRARAPSNAPAPAFVPPLPPINPLRKQSGTRGPRGMLGGLMGGRRSDGPGDEMDTMSALSMPTLPHSASGSSTNLAPKSPNYQLGGSPSDNEGSRLEQRGLRKQASEANGMHSRMMGGGGDMLSQRMDLPGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRG3</accession>
    <name>A0ABR3YRG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="55882" checksum="4497BA47210CF50B" modified="2025-10-08" version="1">MAQKERVTTRLSGWDQVAMRGYMSKALCFPFDNAQMDAAIKHIVASLARMAQQRPDFAGTLEVRDGGIIHHISGHNNTIPFFFEDISAEFPYKSYAELKAAEFPPGAFVHPRFFQPCALAEGQPGVPVLIVKAFTIPGGLFLATYFSHAFADGDCLRIFLETFSRQTRGLAFDGASTKNLNAPFANESNVKDKDGSRLQELLEKVTEYMVLDEPVGPTTPKFRPGGVPMTDITKIGKVFVFDNARLNQLRCSIFGSNEAAMANGNENGNTRGCLSGNSNKSTNGLALSPSNMPSNYTCLAGLTWAHISKARLADSAQYMPHCPETDKMALLQTMVNWKSRALCEANPTYFGNATAIAVTRLSTTDSILSRASSSPSDLAKLVSTIEKTIAGVDDDFVCDRTELFARVPDPRLVGLRFDPRTPQDLGFNTWRFFGMDTKWSIPGVHGGTDSECDMIRRLQAMWNMSGALILPAKATSTTHELLVTLPKTSMDLLCRDPEWMKWVDRVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS86</accession>
    <name>A0ABR3YS86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPL37_2</name>
        <name evidence="10" type="ORF">Sste5346_007996</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003214">
        <property type="entry name" value="PRK04179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="91" mass="10287" checksum="47B57D3A06A15CE4" modified="2025-10-08" version="1">MTKGTSSFGKRHNKTHTLCRRCGRRSMHVQKHECSTCGYPAAKVRKYNWSEKAKRRKTTGTGRTRFLSGVARRFKNGFRVGAPAAARSTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT32</accession>
    <name>A0ABR3YT32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="69"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="536" mass="59447" checksum="9775FD0932ED917D" modified="2025-10-08" version="1">MADELKTGFAVDAADANNSNSDADYALGETVKAEFADDTRDILEQHGDGVPELTPKTLRTLKNKLYLHIVVFFIFINLMLFIDKSAMSQASLLGVLDDTHMTSTQYNNLNTIFYAGYIVGQVPGQWMIQRLPLRLFVAGSIFVWAVIELLHCVALSYGRMIPLRFLLGVSEAAVVPALEITMSMFFTPEELHTVQPLFWTSCVASPIPSGLVSYALLFSKSSVSPWKFYMVIVGGISLILAGVAFLAYPSNPATAWFLTTDERVQTIRRVHAATRSSIETKRFRRYQFVEALRDPISWLFALSTFCLQLSNNLAFQLSLLYVALGVSDLGSTLVWVAAGGFALVVCIIASFLLHKFPGYSAFWAALWTLPAIAGSIGMVALPWDRTTPLLACLLLATNTWGMTYIITLAWTISSCAGHSKRLTRQGMFMAGYGISNIISPQLWNDTSAAPRYYGTWVAQIVLSFTLAPLLLVVAWFILRRRNASRRVWITQQHAIGNYGEGFLESTAADGSVVKTKVDVSMLDLTDYENKFFLYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTK1</accession>
    <name>A0ABR3YTK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF31">
        <property type="entry name" value="CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="36530" checksum="17E3496FA2ED281C" modified="2025-10-08" version="1">MPLAKYSYSGPVDHTVVPDVKNIAGKSVIITGGANGMGETCVRHFVKAGAFVTFADMNEERGKTVEAELNAGAEAGKPRAVFVKCDIRSWDDQIRMFDTAKTQSPSNSVDVVIANAGISRSSGDSLWRLDDPKGAPTKPDLNIVDVNLVGTMYSFKLAVHYFRQQPDTADRDRAFIMTGSLTAYIDSPGNWEYTATKYALLGLMKTVRRNSWEQGIRINYVAPCYIRSAIRTAEYEKWLVDRGVQFGEQEDVAGCMLRIACDNTINGRSFRIAPRALVKEGFVDIDREDYREGVEADEYFVKNQATQLVIIEDQWRDDYTVRIFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUL4</accession>
    <name>A0ABR3YUL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Low-affinity Zn(2+) transporter zrt2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZRT2</name>
        <name evidence="7" type="ORF">Sste5346_007307</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF69">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="324"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="505" mass="54421" checksum="F8882906D0747C87" modified="2025-10-08" version="1">MKRYHFHSRLLDPNCHAVREYTYTYLPIMRHYVVQRDTDAPDVVPQCSGWGTDLSDKGLRIAAIFIILAGSMLGVFLPMILARTSSNSRYSKLVFFVCKYFGSGVILATAFMHLLSPAVEALSDECLSNILPEYDWGHVICLITIMVMFYIELMAMRFNFNFGHSHGGPSVSPSDLSKKTDNKDHAHDHGNGQAKHASGRTPSRHSVRSVNNNANSNGNANSNGNSNPPSGPGMTEWRQSVNNSALSGLAAYATANLERNDRDPHHEPDLESGTTSMSVKSVSSQNKNEASANAASVAAEPGVLAPVPTGNGGLPSHLNYPPGNEDHLAHDHEHVNGDSHASYGSQIVSLLILEFGVVFHSLFIGLSLAGSDNLKVLLIVIAFHQFFEGLGLGSRLAVAAWPSNWKAWTGYLMAVGYGVTTPIGIAIGLGVNAGLNSHPDKAQLVNGIFDAVSSGILVYTALVELLAHEFMFNPEMRDAKLSVQMLAFLCVAVGVGLMALLAKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUT5</accession>
    <name>A0ABR3YUT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="150"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="218" mass="22997" checksum="8EFB0E37CEED61EA" modified="2025-10-08" version="1">MDDIQPRIRQLAADIDRLEAAVAPLLLSDASGSSSSNNNHAAAAMHLPLLDKAKLHVLASFALESTLYCSLGLAGVDARNHDVFRELQRVRQYMGKIDTAEKPPVVEPPTSRLNKSAAIRFLKADLDDSPDVKSQLNDLLKQEQAAAVAGTQSESAAARAARAANNASPRGRKRGGGAATGGNASGSLTKRPKHGSGRNSPSGDARSRSHPYSRGSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUY5</accession>
    <name>A0ABR3YUY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="554" mass="61806" checksum="222055622DD19FC7" modified="2025-10-08" version="1">MSYIEPPTLTNIRKRKRSARSASVASSVVSHLPRDAIDPHSYGPSARRQLVVAGLSHSDRLPTDYVEGFPHRALPDGVGGDEDENAKARKDKDSFGTGFGSGFGLDGLDDEDDIETDSDDDNASINSESGMYDTTEDDDTDTSGDPSEVAARLAVKQRRIRRKEARRRRNALRMQRAYDQNVGVLATIVQRGLQESEHGTIPSVLTSTGEAGRLAAPIGLARAKRAFGLIVRTEIKGKGVDLRRNYLWAMGAELLMREGEDERNEKNTPAGSRRWGLAANMPRVRAFYEDLIQQHPYNRLFPRSVNALTFWPAMAGTELYNIYAEAQLATEHLDAKAREKQKKKDKKAHAGSDDGSYESEHDSGPDSDEGHFSDNSNDSNDSNDSNGSNRRRRCQRDHPDRLAREDNRLSSLEQLRDLTRRMDAVMAGPPYATSPEMLRLRGMVALYMGDLAIVTPPRTPSETQEGERVRAQERSRARARFARLLDVDRDIQSGRHHKRGGVPDTAVDAYIQKLARGASEDTHDHDSNSEEDDDTVDQGRSRPMFTSLSYRSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVA0</accession>
    <name>A0ABR3YVA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peroxin-16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="455" mass="50307" checksum="335C2509BDC1D2B5" modified="2025-10-08" version="1">MASSQAPAAGRATSNGTRLSPAKWLSAYDDFIAKNLGQVSQIESTLRSLTYIIPGRFRDAEIASEAIHSGVQLLSLYHDLLLLRTPSVSSPPTPSGHASTRASKSPLGPSQPPSHHTRYTRFWTHKSPFYRRVAIVLQVVRYTELLCEMAGKRRGERLRWRVVILIEAIKAICQLLLFRITRGRTLLTPALPVRQPLPENDDEEEEEEEEEINQAGRTAGAHGSAIGEGKENGLVPSQKTSISPQPPLSPPLSPLQASAELVVEDGQLSTLTPPSPPSTIGQSSPASHTKGWTMPRTKMSMPPLPQPGDISSYLLSRVLTADDIKPATKLLNQLHGSAQVAEILHILTPLVYAIALARSREKGRTSWAPWLAGLAMECAARQLRDHSLRTTSLEREEWSRRGWAMGWWTMRGAFYEHVMKGVVGGVRSRVPSFVGGIIEDYEYLWENYYFSTSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVF3</accession>
    <name>A0ABR3YVF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="194"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="807" mass="89538" checksum="FEB3B114BD989127" modified="2025-10-08" version="1">MTGKNDNPTEHNVCQGCHVYWFKLKMWHSSEHPALKTSVTQIEAAAATGNCPCCRVVADSFKVMTTEWLAKVQRNPISVLMRTDSVVIQLRGVDSPSGVAIYGHTDGPRFEGEASFAVRSEVMPNTQSEDAFRAANAWLTECVKNHPGCAQPFFSTTPGKKTADAFVPTRVLDVGGNNKDRIVLVQNAPAGSPYIALSYCWGPDPSGTVTTKKNNVAVHMDPQRGIDLSTLPRTIQDAVLVCRRLNVQYLWIDALCIVQDDGDDWRREAAQMCNVYQRSHVTIAAHRASACQHGFLGAQEFGKDEHQSVFWTESEKCSEDGMPLKKAKMVLRAEYKDIHTLPTAPLGSRAWTLQEVVLPRRILHFFEYEMAWECQTTHHCECGETTGFEAPHLPMLGLGLRSLDDDKKKIKAGDDGRSVIAKLNWMSLVEQYSRRSLTRLSDKLIAMDGLARMVEGATMASSQGGAPVSRLPPLSLDNTVIRSAYVEGLFVADFAQQLMWGVSQNSMAASAPLSTTPPQPTARRQSPDLHAPSWSWASIDAPVGYTIIYTEDIESLIRVNDFSPHTVVGGKAKVTGVRLTATVVPAAIRTMAPVDTITGHDGPARRRQPLTSRPTIVRACNGFSYAVFCDDVQAPDLLMDSPELPCWVADDSMHNTRVRKQWLSTHESTSDTDTDNALIRSCQHNRGRHIRQVVHEEDEPGRANKDRWCDACRVWPSEDAAWQNIDANITGNVSPPTTVVSGLYLLMQVFRKREAGSHTVYFLALRPSIKVPDAWERIGHGRYVLWDKASPHVDLFWGSKSRDLLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVS0</accession>
    <name>A0ABR3YVS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18109" checksum="8B2C75A96BCCFA16" modified="2025-10-08" version="1">MTLWLIDHGADPNQRPVIDTTAMSMPALYAPPSLIRELLDDYGGDIHRGQLLHHALDRQSTTGRNGDSDTIKVLSLLLERGAILNRTMDADDAPSRIMYCFVDHGTPLHKAADKSNIKAVRYLLSQGADTSILSSKKKTALQWAEAAGRKDVAAMLRSPDQYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW84</accession>
    <name>A0ABR3YW84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF63">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="276" mass="30129" checksum="770161911B2197B1" modified="2025-10-08" version="1">MDLPTVVIEPSAPHTHTVVFLHGRGDTAKNFARTAGYSWGSDNKPLYGAFPCFRWIFPQAPVRRCANGNGIMHQWFDTWSTADFSEREELQVFGLQEIVPAIRLILAAEAERLGGRWDKVILAGISMGGATSAHTIFNLAIPPPPPGSVIAADHKLNRLGALMTFSSRCPYVSRPLEELRTILGLPDVPDNAEVLKNTPMLLEHCTDDDLVPISTGHALRDTMLRFGAQVTWKEYPDGGHWFNAPSGIDDAVAFLKKHLFGENVGEASSEAATAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWV7</accession>
    <name>A0ABR3YWV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF102">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="42871" checksum="FB1AEA3999413908" modified="2025-10-08" version="1">MASDGPHDEMADVPPSVSAAGPSASSTPATAPVTSDAASAYSVNAMSGYSVGLSVDTDDRDNDNDSSLGDMDTQSSTRSATSSVYHFVEEFGRTFHKYKEGKYFMPNDEQEQNRLDLQHAIAKHCLGGALGLAPPNNTTDDVAAGGLTDTTEGVAAPPSTGPDGPVSGGAHRVLDIGTGTGIWAIDYAEQHPAADVLGTDLSPIQPEYVPPNCRFEIDDLDDDWAFSSANKFDYIHGRYIVPFLKDVPGVIQKAYDHLQPGGYFELFEGPILFHCVDDTLEGTTIKEWNDLISAGVRKIGRDPLAALKLKQWMEAAGFQDIQEKRYALPINPWPRGKENKLLGHMEMTNLLEVAHGATMTIFTKALGWSVEATEVFLTKVRQDLRDRRIHAYLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWX5</accession>
    <name>A0ABR3YWX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SUV3</name>
        <name evidence="14" type="ORF">Sste5346_007199</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="341"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="490"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="763"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="490"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="519"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="818" mass="90517" checksum="13518ACE81A553D1" modified="2025-10-08" version="1">MRRDFDVSNEPSESGRRQTSQTPDSRSKGRKERGSGTSGGRNARQLTTGRIDQGFSIDSRKYHLFGALVDTRFSYMLKDLGDWEPDSGAMQAFGIHSQGELDRQAKLFRTVLSQSIHLAASKRIVSRPENPLFWSLRNAFVRGDTMGLSKELRYAFQSFILRPSLTPAVNTLQENIADFRYPYEWYPSTRTMQRTIHLHVGPTNSGKTYRALLALENAQSGIYAGPLRLLAHEIYARFVAKGRPCALITGEEQRFPNADGTPMDPADPASVMAAMGGGGVADTYFQSCTVEMTPLNKRVDVAVIDEIQMIADPDRGWAWTQAFLGVQAREVHLCGEERSVDLIKALCAHMGDKCIVHKYERLSALQTMKESLKGDFSNLRKGDAVVAFSRVALHTLKSGIEAATGRRCAIVYGSLPPETRAQQAALFNDPDNDYDFLVASDAIGMGLNLEVKRVIFETATKHDGINFRHLTVPEVKQIGGRAGRFRTAAAAIKSDSSKNASDKAATPSPERSEQFSPSTAAGTDVGTDVGTNTGGGAAKKWGTPGFVTTLDDEDLDIIDEAFQTEAPPLKAAGIQPPIFAIEQFARYFSPDTPFSFILSRMRELAQTSELFQLCNPKEMIEVADIIHPFPMSVQDRCIFLAAPTSLRDPGFRSVLEAFARCVSEMRGGALLDIQELDLEILDIEAEEYPGGAPKYLLAVEALHKSISLYLWLSYRYIGVFVSQQLAFHVKGLVEAKIRQYLDNLTFVPERQRQRVEALRKLAEKREKSDSNKQQLLAEEEEEEEEEKKSMDKDKALADVVAVEAELDQQPVSSTAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX22</accession>
    <name>A0ABR3YX22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="295" mass="32501" checksum="2A5BB22C8329DAC5" modified="2025-10-08" version="1">MPRDPISSVAGSTTRGTAATSNKDYQQLSPHGVDGVSTQDAVCEQNQTMDRDLYVEDAQQLQTKHSSVAAITSEGAEENARLRAKIQQLQSDAEAEQITLDNMFVELTRVEEELQDTKARLADTESECEGLRATLAQAGGSGHGAVLGNSTTTIGRSSPVMQQTILDLTASLRIKDESLKTKEADLVNERTTQIQLSQTPQSTLEQVVAQTHMCDAVVLSQNETGAREYSNSVGELQQHVRFFKANSERLAQIVRDLKDQNWRLSEDLEVKQRELEDVVSMNLVLKMQAAPEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX53</accession>
    <name>A0ABR3YX53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-fructofuranosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006941</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18621">
        <property type="entry name" value="GH32_XdINV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="53"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="477"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="628" mass="68998" checksum="FDC128E1CBB286F3" modified="2025-10-08" version="1">MAAVVDQCALPPSSEPQRSKTSTVVAVTAVPEVSPPATPPAVPSSWYTRPRFHLKAPRGWLNDPCAPGYDPATGTYHLFYQWNPNRCDWGDIAWGHCTSRDGLRWTHRHASEPTLRPDQVYDDHGVFTGCFWPTGPHDEAGKTTVVYSSVRDLPIHWTRPYTRDCAGLALATSTDGGNTWQKNTSNPVLTGEPDDIVVTGFRDPYLAPWAAMDDVRGVPTDAEPQTLYGIVSGGVIGKGPTVFVYTVPANNLTSWTYLGPLVDILVDQHPASHWSGDFGVNWECANFMTLECESRQQDFLVFSTEGGLPRSTNNTARTAAHNDGDVRSGTYTLWMAGKLQSAPQTAQTKTKAPPWQPQYSGFLDCGSFYAPNTYQHPVSGTRVCWGWIREDSQLDLARREDRGWAGYLSLPRELFLLCLTGVTSASKTPLADIPSIEAVPKKDGVSTVYTLGIRPLPSLVDLRKAPPRVWSSLRQSGPLATARSAHWEMQATIQVSTATQGVGFHLRHRPDGSRGVSVYWVPDEEKLVVDTRRSTEEADLIPKEALSGPLTLFTFADGTTESLRLHIFCDGDVLEVFANDRFALSTTVYGGTETCRGISCLVEGAEVAFVFESIQLWEDLDSVDTSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXA8</accession>
    <name>A0ABR3YXA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053161">
        <property type="entry name" value="Ulvan_degrading_GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36848">
        <property type="entry name" value="DNA-BINDING PROTEIN (PUTATIVE SECRETED PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36848:SF2">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17132">
        <property type="entry name" value="Glyco_hydro_106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1035" mass="114128" checksum="B9A3C0FDE2893C16" modified="2025-10-08" version="1">MKLVRFIASLLPLWKWGCNHDVDTSHKTSLDTPRDIAFLNPPVSYRPRLRYWIPDAHVDLDQIYNDIAQAGARGAAGVEVLGFYLYGASPGAYVPTDWNAFGWGTPAWKQVLDTAIDAHWDHGLLMDVAMGPNQGQGVPAHEDDDGLMWDLKPHHVVVPAGKRFNGTLPGWGAGKLQAVVTGRITSTTKLKATEDDEDEDDEPRFFAAEKPPKKKIRHTLDESSLQDVTSQVSKDGWLELDAGTFSSKHSTLCFAVYLVRSGAHTQQPPSILKGPQTTPTDYVHNGSWTVDHFSARGARVLTDFWETNLLVNGTREHLQEVARCMWEDSIEINPNVYWTPDLPRKFARSHGYSLGKYLPLLFHGNSLVDHFSESFVTDEPDAGHSHVAAYRTTLTEGYGEYLDALREWAKSCFGGDVAWSSQIGYNMAVDMQALVAKADLPECEDLAFASNIDAYRQFTSPAYLANKNIVSAEVGAVLGHAYQMTVPRWLQLIHRLFAGGVNAVVMHGLAYSGAYPNTTWPGYAPFTYAWSDMLGRHQPAWDFFGGPFDYLSRTMYLLQQGVPKLDIAFYQKQTTYKTPTTNYEPEDLLRAGYTYGYLDPETLASPEAVVHNGILAPSKQAYKALIVRSSDTISTARDADTLAKLAHAGLPVIFAGHSLPSFLGSHHNPAGKVYVHQTLHSLRLLPNVHHVPDEDGLCEVVASLGIEPHTRVRSSGKWWTVWREDTDRQFAFVYHDGDEPSSGSIEFQSTGRPYQYDAATGQVTPIGVYSQKGGRTKIHLEIGPHQAILVGFHNDESLGVHATSTSKGVVDVRRENGQLVALVASSSSQWVRTSDGVSYYVHIHNVPPPLHLNEWTLTVEHWDPPQPLTNIEAGPHKWNSSHNLKELVSWQDIPGLRNVSGRGYYTTTFDWSGNGGALLSLGPVIHTLVVTINGYSQHALTSDAIDISSFLVAGRNTLTVVVATTLANCLAPIWDSLRTSGAPPTGLFGSETRPPGDAEYGLLGPITVRPYRKVTLEKGEVESDEQGLGLVKQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXC8</accession>
    <name>A0ABR3YXC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1275 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF2">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33262" checksum="CEA6225F0B5FF5A4" modified="2025-10-08" version="1">MADTQPPAAQLFVPPTLTSHAASQSSLEGTLHGQDTQEKKETEKNQTQPTTSPSSTPTTQPTENFTRSGNAVWNHMTATIRPTLLAEAELILLTIFTGMQDAVSFPDYHCFASNQTGNTVFLMLALVLPELNGKMFVTANIGAALGFFLAGGWLTGQLSHIIGPRCRLWLVACNFLQSGMVFAAGAIQYVYGIDLEGSRAIAVIGLLAFASGSQVVQSRSLAMTEISTAMATAAWVDLLIDPKLFAICNRPRTRRVVFLFALVVGALLGAAIYRTVGSSVAILVSAGGKLLVAFMYLFNEAEKPKVEESTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXD5</accession>
    <name>A0ABR3YXD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006731</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="47"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="527" mass="58745" checksum="E41F5F5625F1C9EC" modified="2025-10-08" version="1">MANNDTLDEKEARIEASQMVAINLADVIPVNPKPWYLTKHLALLNMLLIIPLLSAATIGFDGALMNSLQALKPWKTYFNHPNSSILGTMNAIFSVGKILGIGPAAWMVDRYGRKRPIWIGLVCLVCATVLQGAAQNTAMFIVSRLLLGIFTAFIAQASPILVAELAFPTHRGKATALYQTTFYVGSIYASWSTYGTSHMTTSWSWRIPSILQGTLPIVQFIFLYFVPESPRWLIAQGRHTEARSLLMKWHGGGREDDEETVAFIELEMRQIDESVTTEQHVMKTTTYLDLLRSPGNRRRTLIAAIVGFFAQWNGISVVSYYLTLVLNNVGITDATDQTLIAGCLQIFNWIAAILAGALMIDKLGRRTLFLVSVAGMFFSYIVWTVLSGLFTTDSTKYHNLAPGVVAFIFVCYFFYDIAWAPLLLAYPVEIFPYALRSRGVAVTYSSTFIGLIISQFVNPIAMSHLGWKYYCVFLGILFCLFFAIYFLFPETRGHSLEEVAEIFDGPSGNDSTTAHGQKVELSQVEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU8</accession>
    <name>A0ABR3YXU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multicopy suppressor of BFA (Brefeldin A)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BFR1</name>
        <name evidence="3" type="ORF">Sste5346_006608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="360"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="170"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="501" mass="55754" checksum="21E28AEB15189450" modified="2025-10-08" version="1">MAAETATAPAADATPAAAARPQKPDEDAYKKALDKAEKEHKDVMTRFNAIKAKIESVQPKKDGPPSPAQQRRQELIAQLNEIRQKQAGGKTARTSKLDQIKRLDEQLRNRIAEQKAARGKVPFKSVEDLDNQIGRLEDQVNGGMMKLVDEKKALAEVTNLKKVRKNFAAFDVQEKQISELRASIKQIKDSMDDPEAKALSEKYNGLQAELDTIKAEQDGVYKNLSSLRDERSKLHSEQREKFDAIRKIKDEYYGAKKAFAAFEREARNKARERKQAEREKFDRERQKERAQRMLAEASDPAYLDEIRRGRSLLKFFDPSYVPSTDAAADSNGSKSLAAQDIRKVDDAGLKGTRLVRKEDREDDYFLPAAKKGGKKGGKKDKDAAAATSAKGFNVPPSVIEDCAAMGLNPPTSAADVPDVIEKVKAKLEHWEKDQDAQTKRNIEKASKEIEKLEKEEEAAASGDKKADDKAVAEVTADLKDSSLDEKKGEEAKEAAKEETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXX0</accession>
    <name>A0ABR3YXX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U1 snRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRP40_1</name>
        <name evidence="5" type="ORF">Sste5346_006835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25432">
        <property type="entry name" value="FF_PRPF40A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="167"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="236"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="383"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="517"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="581"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="589"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="831"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="859"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="898" mass="105017" checksum="1D5E40069ADEAD4C" modified="2025-10-08" version="1">MSGEQSPAAGGATPSAVATSAAGGWVEYRGPDGRVYYHNAAFGKTQWTKPEEMLTPVERALLNQPWKEYTAEGGRKYWFNTETQKSSWEMPEVYKKALGQDLTPAMPATPVAIPTGPAAQRDRRDYQRDYRENIPESRQLTFGNGHDSTSGAAGALVPTNSDNLPDYPNPEEAEAAFVKLLRRSGVQPDWSWEQALRAIVRDPQYRAIRDAKARRAAFDKYCHDVIANDKERAKERLTKLRADFATMLKSHPEIKHYTHWRTARPIIEGETIFRSTNSEAERRQLFDDYVDDLRRVHREQRTAARKTAMDGLVELLPKLNLEPYTRWADARPVLEATPPFVNDEKYQSLSKFDVLTVFQNHMKALERTFNDARQEEKTAKLRRERKNREAFAALLGDLGRDGKIKASSKWSQIFPLVQNDQRYLALVGQSTGSTPQELFWDLVDEEQRALRGTRNDIEDVIDDKHFEVTPKTTFDSFLAVMKDDRRTANIDREVLALIFDRLQERKKEKRSDDDRLQRRALDDFRALLKRVDPPLTATDTYDKVKPRLQKSEEFLAVSSDEAREAAFDKYVRRLRDREDEDKDRLKQRRDRDRRDRSLDDRSRERERDRDRERERDRDRDLRDRDRRHRGSRLSARSRSPEADSYEADRRRAMAERERNYRKSSVAAESLDGRDRERDRSRGDRDRDRDRRDRDRDRDLRDRDRDYDRDRDRERDRLRDRDRERERDRDRERDRDLDRDRDRDRLRGDAESHYDRERREREEERERQYRRRLADRNLDELNYGDDRPSSNSKPPSVRRRNREDDDAADRRDSRDSKRIRREYSPRERTPQTGASTPAPAPSGSAPPAAATGDKGENGKPKSSTTAARSAKAKSKSAAGAAADGEDMHSGSEEGEIEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY30</accession>
    <name>A0ABR3YY30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alpha-aminoadipate reductase</fullName>
            <ecNumber evidence="6">1.2.1.31</ecNumber>
            <ecNumber evidence="5">1.2.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">L-aminoadipate-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">LYS2_1</name>
        <name evidence="20" type="ORF">Sste5346_006466</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) = L-2-aminoadipate + ATP + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46936"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.2.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(S)-2-amino-6-oxohexanoate + NAD(+) + H2O = L-2-aminoadipate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12308"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>(S)-2-amino-6-oxohexanoate + NADP(+) + H2O = L-2-aminoadipate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12304"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.31" evidence="6"/>
    <dbReference type="EC" id="1.2.1.95" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014397">
        <property type="entry name" value="Lys2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03443">
        <property type="entry name" value="alpha_am_amid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF1">
        <property type="entry name" value="L-2-AMINOADIPATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001617">
        <property type="entry name" value="Alpha-AR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="12 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="19">
        <location>
            <begin position="628"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1893290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1179" mass="128150" checksum="8ABEC59A791855AC" modified="2025-10-08" version="1">MAGPAPPDPTIDLHWDEFRGAIHDIFAANAKKFPDRECVVETKSSQSPERSFSYHQINEAANRLAHHLLAHGCQIGDVAMIYAYRGVDLVVAYMGALKAGATVSVIDPQYPAERQKVLLDIARPRFLVCIDKANRESGPLSAPVLEFVTTTLDLKSFIPALQLCSNGELHGGVPVNSTDGKDALDPETYSGEDPVGVDVGPEAAPTLSYTSGSEGRPKGVLGRHFSLTHYFPWMAEQFGLSDQDRFTMLSGIAHDPIQRDIFTPLFLGAKIIIPPVEVIAYELLAEWMKESKVTVTHLTPAMGQILVGGATARIGALRNAFFVGDQLTKKDTTKLRNLANGANIINLYGSTESQRAVSFIKIPSKNENPDILDTFPDIIPVGQGMQNVQLLVVDRDDPKRLCEIGEQGELFLRAGGLARGYLGDDEKTKELNRSKFVANWFVDNPEPRDRLYKTGDLGRRRPDGSVECTGRIDSQVKIRGFRIELGEIDAHLSQHPYLRENVTLVRRDKNEEHTLVTYFVPETKRWFQHLEELEAQGATRSRTSRAQLDVQSPDESIGQMLLRFRSLSEDCKKFLAGRLPSYAVPSLFIPLARMPLNPNGKIDKAALPFPDEADLAFLAKRRASSVAPKLTDTQQRLASIWASVIPNCFARTLRPESNFFDEGGHSILAQQMFFRLTKEWKDIDVPMRAIFQHQTLEALAAEIDRAQDPIGLRLDAVPLENDANVEDEAYAVDARELTNQLASNIPTAPATTEGAPTVLLTGATGFLGSYIVHELIEGPTKSNVIALVRAKDTAEGLVRLESVMKAYGLWSPAWLTASPTPRIQVVVGDFAKPNFGLTEDVWTQLSNTADAVIHNGAQVNWMLPYSVLRAANVLSTLTCINLCASGSKAKRLAFVSSTSALDNDHYVHTAAGPNGTPVLETDDLSGSRKGLATGYGQSKWASEYLLREAGRRGLVGAIVRSGYITGDPVTGTSVTDDFLVRLWKGCLQVGARPDISNTLNAVPVTQVKRIVVSAAFHLPAAADGVSLAVAQVTGHPRPTLNDWMSALEAYGYAAPLVPYKDWAAKVKAYVDDEANAAAGREHALLPLFHMVVNDLPGNSLAPELDDRQTQGALKLYDANSKPSDNSVPITTMGSYLAYLVAAGFLPAPPAGAATPLPQLSEAALANISAGQLGGRSAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYP8</accession>
    <name>A0ABR3YYP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NPY1</name>
        <name evidence="12" type="ORF">Sste5346_006579</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015376">
        <property type="entry name" value="Znr_NADH_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF6">
        <property type="entry name" value="NAD-CAPPED RNA HYDROLASE NUDT12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09297">
        <property type="entry name" value="Zn_ribbon_NUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="11">
        <location>
            <begin position="265"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="427" mass="46651" checksum="4BC59A9D039DED48" modified="2025-10-08" version="1">MSILPVADLPELPPDNSMLYRKFGREVANYFSGSPLNRVSFLRTDHKFLRAAFAHPSARFLLIDNLAPLVHDSTPPRLAWSTRAEIASVVESDPFERTEEEAIKNYNSEKDPLPIVLFLGIDEKNKFSDPSDAAAAPTAEAPFSFNSFSGSPYFAVDITPRGGTAAKATALIEASKAKGFSFFANPRSMSLSAEEAAVYGQARGLFDWNARNPFCAGCGQPTLSVNAGTKRACPPTDLAGVEAGGEPKERRPCETRKGISNLSFPRTDPTVIMATVSADGTRILLGRSKRFPKYWYSTLAGFLEPGESVEEAVRREVWEESGVTVGRVVIHSSQPWPFPANLMIGAVGQALPGDGEKIFLGHDPELEDAKWFTMDEVRRALQYETAGLDDPIRTGYKEGDLRLPPKTAIANQLIASVVEGFHEQPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZD2</accession>
    <name>A0ABR3YZD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006429</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="8">
        <location>
            <begin position="296"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="663" mass="74075" checksum="E09F7A7C0E43E2EF" modified="2025-10-08" version="1">MLSLRRVAAVSPLAGMAMRRTAAATTTQQLRSFATAVGEGEGEGEASSTNKTSAEGQKKVKNDVKKDVKITYGVNKKSPPRGLPPRTSPPKPTSPTPLFPHLRENISGESVVTKPGDSKLGVSSEPAVGGPAVDGELQSAKFFRDFSMIDLRFKGLQQPVSVSTLWLRDTCTCPQCVTPSSGQKTFHTHDLMPRPHVEECNVVTDAATGRTSLRVVWAAVPEWSAKEAENKGDAENKDDAPAAAATIKSAMEAHESLYDSQELLYRLAKYDPARNYPGYLPRRLWDRSTIEKALKPVSYADWMAADDGNNAEFYRGLLDLHELGILIVDNVPDSETAVKEIANQIGNIQNTFYGELFDVVSKPQAENVAYTNVFLCLHQDLLYMNDPPYIQLLHCLHNDCDGGESLFSDSVRAAVEMQVAEPWYALALGKEPVRYHYERNGHYYYNQRPVLELQHAYEHTDDMAASSIKFTAWSPPFQDTMYHWLSSADKAARKESVSFETRPKAAQYKNLFKYGTAAQRLAYWRAAAGRFSQRLEDPNAMLELKLQPGQCVLFNNRRVLHGRQQFNTSDGTRHLKGTYIDEQTFHSRLTNMVRSGRLPGREKTEAELKARPMGQPPFGPFPPPFAKRALLDQEQVVAMMEASGRLPAWWARRGVTKDEEEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z014</accession>
    <name>A0ABR3Z014_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="93"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="38693" checksum="F941D2315AD3DEAF" modified="2025-10-08" version="1">MATHNPDGSAASLDATNIDPLRDTVYDFPRDLVGYGRSPPSARWPNGAKIAVSFVINYEEGAERSVQNGDAQSENRLWEQSDNKPAQMGARSLNPESDYDYGSRVGVWRLLDCFEKHRMPVTAFAVGQAFEKNPAVAVAFCQNGHEIASHGYRWVTYNGMTPELEKEYVKRQLESLKASTGKYPVGWYYGALSPRSKAIIHEIYKEMGIPLLYESDSYCDDLPYWVDVPAEKDSTDPKGMLMVPYSYDCNDVKYHTASGWSTTSDFEEYLKTAFDVLYEEGARGSPKMMSIGLHCRISGKAGRFAAVRNFVEYIAAKPDVWVTTRKDIAQHWRETYPYKKGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z083</accession>
    <name>A0ABR3Z083_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="3">
        <location>
            <begin position="119"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="368" mass="39004" checksum="227AA994ED737D78" modified="2025-10-08" version="1">MLLNGGGGRLRIFVLTAVILFGIIFLWTTNGRPDPATIKNTVASWPAAVTSHFTPDEADGSADGNADTAANTPSNGPSNGPAGNKEEQPPPSYDITPLSGNKGSNGKAVTETDAPYFILIGDSTTRGQLQNGGGWGDAFLWLLARGAEGTNQGVNGALSTGYFHSPMWNDAMQAVRAYSPARKVYVTIQFGHNDQMPNSNVTLEMYQATLEGMAREVLEAGGTPILVTPLARRDFDADGTTVTDNLKDYRERTLAAFDTLKSEGLPARAINLNAASLAYVGAIGKTAAFRYNKWHPFGADTTHLNELGAIVFARIVADLILGHPATPLIPSGQPDPWSPGEGNDDDGLSGWIPPDPYISGLVWHGDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A5</accession>
    <name>A0ABR3Z0A5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="32191" checksum="6767AC13D72027A8" modified="2025-10-08" version="1">MPRDVDTILHYYADPGDGSEPTPIYVGQGTVTNERKMAQVQVTVHDITERESEFTLDKTGFQLVTRPTTAAACVADNFENVDLIKSEYFPDTVNLLKEETAATRVFIFDHKVRRGPADWHSRGQGNASQRGPLHRVHIDQSYDGADFLVKWFLPDEADTLLQHRWQIINVWRPLHTIAKDPLAVADAHSVADTDLVEARVVYRDHTRKTWTVKAPPAGSPPHKWHYKHQQTTDEVMLIKCFDSADDGSVARRVPHSAFRDKEYDDAPPRESIEVRALVFYHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1F1</accession>
    <name>A0ABR3Z1F1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596:SF3">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="50480" checksum="487C77F34FF47F30" modified="2025-10-08" version="1">MQGALAQSLYFQFADHAVAPTDEMTKLYMKGLADARYMRIWQDIAIEQIHLRGWFKSIEDETKPSTLSLVSLQRALHFRTVSDPADEPLCIATLLSLDQKYVVGASTLQDRMVRVWELIAKKLGGTVPARILFSSDETLDVPGWRWAPRSLLGASDATKDSVMDVHHRIMRFRAWRSDEFEAEDTMRASGVPTPWGLRVQMGGYILKSIPLLQHLPLHPWERVAGSHEDMILVKHSASGRWLRLMDFYRLEMSKKWSPEERREYDRRTDNLLCRLIDSGGQALLYDRSPQKGQYYPSLMVRFEDGWNQQADVGARQTLRARRERMVIFDWASPAHTIVAEGLEELALKVAKSDVTERFLKAMDSVSDWEQGRRAMDQVKDYMKAVVAEKWAYDPAFVEAVRDTRGPKMEDLLWAEIQMRFSHSIVCEEVPDSQAWLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1T5</accession>
    <name>A0ABR3Z1T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="31668" checksum="EF92D6266F7E122D" modified="2025-10-08" version="1">MAPIPIYSQSPLSAAKPDGVTPKTDSGSNNNAGRYVPETPTKTRPLAAGAGGPPPPQPGAIPTLPQPTGSIQSPSNYGQYAPPPPATTSAASSASGRTSNYTPPPPQPGAVPVPPSTAGSNYFQAGQPPAPPTTTAAAVLPPPPRAGETLASTGLLNKQAQPAPPTTTMPPQMGMPPVTDAPYPGAARGTSTGYPGIPQPTGLAQGLAMGQQQEQQHINLDHPPGYVQDAYAAEMTGSQRAAAAQVGTSSGGGGGGLSSYHSSSAFNNNNYSSSTFDDVEGEGLWDAAKKLAASAGQKLSEAETEVWRRINSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2K9</accession>
    <name>A0ABR3Z2K9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="127" mass="14722" checksum="D34EB37382BA34C4" modified="2025-10-08" version="1">MTSAWLHYVSSNQFLTELRGLTPNYPFSTDLLADAQQRVLTDPLSNRSWNMAWLCLSKIRDDNLIPLYAVAEANKPEMWGGAYDQETGQAYQPQPEECAQLASYFEYEWTQAVTTLLRHWPTPPTWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y7</accession>
    <name>A0ABR3Z2Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF1">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="7">
        <location>
            <begin position="26"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="463"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="587"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="633" mass="68547" checksum="8C9DAC6F185A6E87" modified="2025-10-08" version="1">MPTLALTDFNIVVSVLGGWVSLFGLVSYLCKEKFYLSEALISLLAGVAFSPSAANLIRPLEYAGSQANLDAATLYFSRLVLGVQLVLAGVQLPSRYLQHHWRPLTWLLLPIMTIMWLSTSLLIWGLVTPRLPFLHALVIGSCATPTDPILSNVIVKGRFADQNVPLELQRIIIAESGANDGLGYPFLFLALYLVQYIGFDATPEFPVPGGGAGKAIGLWFGETLGYTILLSIVYGAVVGYIAKELLHWAEERKFVDRESFLVFAISLALFIVGTCGLIGSDDVLACFIAGNVFTWDDWFRLETKDDSLQPTIDMLLNVTIFMWYGAVCPWSSFLHGPVPLPRLIALGILMLLLRRLPWIMAIHKYIPQIQDWRQGIFVGFFGPVGVSAIFYLYITLDFLEKLSPPELVDGTDNPARLRPDVATLGETTTSVVWFLSIVSIVVHGLSVPLGKLGFYLPRTLSRALPSSPSSASLGNSDGVLTGRRPRHGPSLPAFRIGSRVNTLSIQPTGDGDTSPGAQQPDMMSSDEQVQQDGSGADTSLDKKVSASSSPPSGGLGSRQIYRIGGSIIRENPADSSGSSTPNRRPVYEGTEGSGNESGNNYSNSPSPRLPALSASPPPPPSRTIRFPDDPPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y8</accession>
    <name>A0ABR3Z2Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">mRNA 3' end processing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PCF11</name>
        <name evidence="3" type="ORF">Sste5346_005787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16982">
        <property type="entry name" value="CID_Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054127">
        <property type="entry name" value="Pcf11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047415">
        <property type="entry name" value="Pcf11_CID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021605">
        <property type="entry name" value="Pcf11_Clp1-ID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21936">
        <property type="entry name" value="Pcf11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11526">
        <property type="entry name" value="Pfc11_Clp1_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="6"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="890" mass="93826" checksum="9475E66B055AFE3B" modified="2025-10-08" version="1">MSYEDQSEGVAADFRDALSELTMNSRVEITTLTVIARENTEYAHGISEVLQEHIKKVAPQRKLPALYLLDSIVKNVGTPYTIYFGRGLYSTFMDAYASVDNGTRRKMDEMLKTWKEPVPGSVDPRPVFSPETTRPIENALIKARTSALQAQHEHMRSEQQLLGRGRPNSATPYRETPTLPGPGGRPGYPPQGPYGQQQQPPQQSYPFHPPPNQTTQTTPQPPAYATAGGPFQPPAQQPPFQNPYGAPAAASRTSLESLNEDVERLIQATKTEFTEKSYDVGVAGRLKALLDLQTILKSQNLEHDKLVLVRSQIDALAVNLPGHLKARIGPTPTPPAATYPPFQPPQSAPAGGAPAPAPGGNPPLSAAVLAALAAARNMAAAGSTPPPQAPAPPPPQPAAPASGVSLDTLLGKGALAALLAARQQQPPQPQQQQQQPPQPPPQTPYVPPSTPQLAQLLQGVLAQQQGAPAPAPAPAAAPNAGNPLALMDMLRKAGILQQQTPPQGAPFQAPAQPPLPPAGLNVPGLANIIASIRGPAFAAPRDPLREIQNEVSFQASSLKQFRPHLLPLMYENLGPPCTQCGRRFRTDDAGRAAKTAHMDWHFRVHQRIVEAEKRGQHRSWYVDQADWIYSRETIDSDGADHGADANGATGSNGGRASGSAAAGGAAGAAGAKLQWIPVPTGSANTNQTCPICQEKFEMKWLDEAQEWVWIDAVRIGSRVYHASCHAEATRSDNNRDHPAAAAHSALQSGNNGPIITKPIPTGPAADRNRHQPVLGKRKADDGFHGNGNGNHRGGKNSARGAAAGGNKHKKKRGGIGGAGGGGNPRRPPDLDRVDPDIGGGGNGGAGSGEGNGGGGGGRFGRNGGKHRGGAHNNDNSNSEEPKVDLNALPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3J9</accession>
    <name>A0ABR3Z3J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome biogenesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRS1</name>
        <name evidence="7" type="ORF">Sste5346_005340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in ribosomal large subunit assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RRS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007023">
        <property type="entry name" value="Ribosom_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04939">
        <property type="entry name" value="RRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="212" mass="23751" checksum="38E4E3837799A15F" modified="2025-10-08" version="1">MATKANSTPVGQRGPKLNVAVEKDTPYTFDLGLLLANDANPATITSAAADKDRHEADLAAVARDGAQALVNQLLTTCRIERTTTDGVLLNLPPVATALPREKPVPEPKPPTKWEQFAARKGIKPKTREQRKNLQYNKETNEWERKWGYKGANKSAAETDWLVEVKTSQYGKDQELADKGHSYRGEGRRERKERFKRNERKMRSNQARAAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3T9</accession>
    <name>A0ABR3Z3T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="44646" checksum="1586F7A4FDB4E85B" modified="2025-10-08" version="1">MGRYDIINSFVRLDLETNVDKKLQRAILDLLHTKTRETNSCQYWAYHSGEMRYCELEEIQRTSRERARIIEGIGPCDADHFFQDHAVPVDGPNYCAPRLEDATWTQAVAASLKNHDSDVTVLYKVIDIGHISGFWTRDTNGNNTYDLAKLVDDWFVSSKNVFATHNGISQGKIVFHEYIHTAEAEAAYAWRRATRSGSIAILTLTLRNNDIRQLERSRRDAVMYQRWTKSDWKLYTWYCMSKIWVPQNMPHLQRYSNADLLIRTMAHREFEHYASIRGENDLRTHKPKEFLYVPEELGRSNETTLSFLLEKGTFNAYLVTSTNIKAMPKIQQLKRVNWQFGTLETDQCDRDMEEDEDEDEVEHDLWDEYYPVLDSDIDMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Q2</accession>
    <name>A0ABR3Z4Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040324">
        <property type="entry name" value="WDR44/Dgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221">
        <property type="entry name" value="WD REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="166"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="206"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="348"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="448"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="546"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="793"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="930"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="546"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="865"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="985" mass="105787" checksum="5D65899E3E03B28B" modified="2025-10-08" version="1">MRAGRKKEDASDIASEAGEPRDDGSNAHVFSSIVDSAGFIPHHKEPPRYIRVKLHNKKVKEFDRMFLAQKLIGTRPLEAHTDSRVTVSTAGQGRRKTATGGAVWATEFSKDGKYLAAGGRDHVVRIWQVISTAEDRRSQEEQEAQDESPNERLSAPVFLEKPVQEFKGHTGEILDLSWSKNNFLLSTSMDKTVRLWHTSRVECLCTFKHKELVSKVSFHPKDDRFFLAGCLDATLRLWSIPDKSVAFSAQLSDMITAVAFSPDGKMAIAGLLSGFCYLLETEGLKPLTQIHVRSSRGRNAKGSKITGITPMILPNARPGDAAILVTSTDARVRLYNLRDKTLDCKFKGHEHTSGQLSASFSDDGKYVICGSEAKKVFIWNATSSDSITKDHYPCETFDAHGDMVTTAVFAPVQTRQLLGASGDPIYDLCNPPPIQLMSLEETLASQSGMSNNTLNHEDGTDAPTSPPHPPPRARPEESPAYIARSTHYDGNIIVTSDDTGIIKVFRQDCAAKKRKHESWETGSNFGQKLGASSRIVGRSGSIITRTSASSAAHSRRGSLSLPSHLTGGAGGITSSGSSPQIGGNPDSINRWRHGIEGGSSRPNSLIGTTPVRSERSISPNKSSRTPLTATAGLASDARKQPYAATTSSPLSPHFAPNQVGRSGMASSATMSPTSAAFAPSARQPGKSILNPSSGDHTSTTAAPSSPAPAPTKIRIEEPKDAHEHDHDHDDHFDDTESEAEHETESEIKPVESLPPTMAYRSDQLRLDPAGASFGFWNLNRWKGIAGLRTSLIGSSSSSNNNEPTSPVDSVHSDKGSENGGGSDSKSAHSRRRSLGVNLLPKSPLSKSETQASGAEGELSPVRPGQTRQKSSGARSSLLSPAITIATEDGDVHDYMDPRLNLGLGDSSHLMTPGGPYARSGSIISRLSSEMTSTDGEGELGEGASGDEGVEMRCTKCGGREFKAKRVAGVQQLQCSRCGKILEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4S1</accession>
    <name>A0ABR3Z4S1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="442" mass="49837" checksum="96AF63F03468A410" modified="2025-10-08" version="1">MSAFKQNQQPVLYSREWSHPKAGTDLWIPPPHHDSPALVRNGGRQLDGVRRSKSPAAKAALNRLMMEAHAAIGERYTLEKYFENDFQGQAKDITTDYAKVVNAFLHLPFKMRYGVAGLHVHLCRLVVARCCCEGRFKKAKELANAARLAHSPPNFEQIVDVPWMDSCPEFDRLEKQLRLPNGHPDMSDKADMARLRVKLEYFYKLMGLKMPSLEPQKNSKEEKPKAPIAVPRPSVKVTKETKARVQHVAKTNVTPTLKPSPKPMLKSKPAPLPKPVETPKPVEQPKVKPAKPSIDSEAKAVVKELQALQTGAGATPAHKISLKRLFDDDNDVEINKSSKKLKKNGEEDKGDKKEEKNDDKKNEADGAKLGASDSEDDDDWIRIVNRPRVPTNSQSTSTSRASSRGFEAHGERITRERIKRKEQREQQNILHQFSKKNSKDHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7H6</accession>
    <name>A0ABR3Z7H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">VCX1_1</name>
        <name evidence="13" type="ORF">Sste5346_004905</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="157"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="371"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="541" mass="57281" checksum="D3EDFDFA0F24693C" modified="2025-10-08" version="1">MPQQPNDGPNGNGNDANKNSDDTASVNFRRGIQKVVNGTYGSTDNADGTGSRVNSILSGGAGNEAAPLLVGAGAASRRSTSGSYIPHVHTAGEHHGFARRLLFDKYHTPGYNSSNVFVRYTAHVLNITKATLYSSPVNVLLVFVPVGIVAGILGWSAVWVFTLNFFAIIPLAAVLSFATEEISVRLGESMGGLLNATFGNAVELIVSIVALRQGQIEVVQSSMLGSILSNLLLVLGMCFLLGGIWNMRDRDNRPMEQSFATVTAQTSCSLMALSMASLIIPATLYSAIDDSADKKAKDESILILSRGTSIILLCLYVLFLFFQLHTHATLFDPETTPSAFVNGLHSDEGSDDEGGSLDGEEEEPHMSPWSAAGVLVVVTLLVSVCAEYLVDSIDEIVASGKISKSFIGLILLPIVGNAAEHVTACVVATRNKMDLALGVALGSSIQIALLVTPSLVIVGWLILDQPMSLRFETFETVVFALSVLVVAYTVQDGKSNYLEGAMLMGLYIIIALAFYVSPGDSLDKALSGVYSVFSSLAPGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Y0</accession>
    <name>A0ABR3Z7Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="237" mass="24697" checksum="B73CFCC8E7FE9FCF" modified="2025-10-08" version="1">MRPQPTLRAAFRSALSASRGQSCASWQSLVASPFPQTAASASRIAATHSFSTSTRSSQDNKSASSSSTASASSSTSTDSAPVLPVSALSQILFSSTTSTPLVGPASTSVSSANPSVYATVQIHGRPYLVTPGDSVRLPFKMPGVQPGDELLLNRVGVVGNRTVTAVAGAGAGTSKVGEESFDVPYVPGATVKAVVLGVETEPLRTLVVKKRRTRRKRTVKSKHHYTVLRIQEVSVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z805</accession>
    <name>A0ABR3Z805_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF4">
        <property type="entry name" value="IMPACT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="3">
        <location>
            <begin position="287"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="577" mass="61793" checksum="C452533B19944F04" modified="2025-10-08" version="1">MSASEKDLQELLRLLTTTRKLPILQAMTQAPADVVKDAIKDAAAAKSLQTSCKTALKKMAAGGSAGSKRIASAAAGSSSAAKRAKQLGGTAAASRSDNLFMGPEPMTAAELERSLELPVFVPTDEEDEERIASTVLMTNRAPLVLAFAVELLRYTMPEQPVSSRLSLAQAVVSANSRSKATSLGMEWAKGPSADDAGWGQGQPRVRILGREVAVLKRSGYTWKGDEEEQEGDDKDKEPAATQAAETDTTVGDTTEDTAPPQSTPQVHNAQSQPAAGIWSNSQTISLKDSTFVARATTITDPGQRAGLLRSLMETHPKLLTATHNAWAYRVRSSYGDHTGSVRQDSYDDGETGCGDLMLRVLHELGAVDTLVVLTRWFGGTMLGPDRWRLMRNCVTGVMAERLRRTGADVALGGEAAWGLDLEAMREQQEAGTGGGSGSNNNSAAARFKHGPSSGLTSVVGMPIHRPEGARQYLMKSFLSAEDTGSSTETTPTKKKKTVKAMDAEKEENLSLLLGALRMVFDSWADHVTAAELDRRAWGWYVAVRPEVEAGPSGWGAKGTLKLKDILALRRPEPKTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z841</accession>
    <name>A0ABR3Z841_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="582" mass="62052" checksum="509F874E9B19D57A" modified="2025-10-08" version="1">MDIKALAALRGLHDRGRTMIRKGAKSRAVDSDTDNDVASNDAEQKLSRAPSLTAFHSRLWMPIGDEEGAFAPRAVAPHAAVPRASSPRTVRFAVSKDAAIETEPVTETKIAGKQAAAEKDEDKVNECAIACTANNDVEKPQDAGQPIDTCAVGNSDAEDDDIDESERRAAFILKAVAKRRAQLRMDEYKKSAAATAGSPTLDANGHLIINGGAVKPARNADGSLISELTMQLRRQDDEVAAAAKALGMIVADDASSSRHSDQSVPPAPHNSPTTSTEHGAGEHPNPLRSNPSGPITPPHTPPFQGAESPQLPPAPPSTPASSNALQLIPRRRLGDVMTPPLSPPTTIPSIVSAVATIISTTSTASSPAMASSSHAGSFSDTASSSLVETFPPITTIDGTLIRGPAFKIPQDAINAAGLSTTGEMSTYAKHSLAWLPHCERPARSFLLGAEVNKALYRHIMQENSLHTRVNYFGPARNESNDALKTTPSITPSAASLACQALRTIKDTDDIDVVTALAPPPFHRKYRPAPRMQKPFYVPKVNTKPIDYNGFRVQPAVPEIDLEAELYRNECYDFANGYNSKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9R5</accession>
    <name>A0ABR3Z9R5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CDC34</name>
        <name evidence="11" type="ORF">Sste5346_004149</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="166"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="25511" checksum="3A41C684CF866B7A" modified="2025-10-08" version="1">MSGAKQRLMSELNALQKEKWLNIEADDLFRWRVSLMIINPDSDFYGGYFNGEIRFSTEYPYKPPVFRFTPTIFHPNVYKDGRLCISILHSPGDDIMSGEQAGERWSPLQGVESVMLSILLLLDNPEINSPANVDASVEFRDHYTEYQQKAKAAVERSKRDIPAGFVMPTSFVEEPPVKKQDNDDAFWAESDDEELDFGSDSDEEMGQDDEDEEDDDSEDDNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCY1</accession>
    <name>A0ABR3ZCY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="463" mass="48727" checksum="948C2C611000D279" modified="2025-10-08" version="1">MATRLTKDIKRRSSPPSSSSSPPPSSTAPQSQPRITRKSSGASSNMAVSIDTSSAHISGQTGDGPPRMLTPPPSSARAELAMRIGDFALNSPVIEQGASGGGPPPASDKAPTGSAFFTQNRAILLSGLPQSPMSKESPSPGQTQRRSLPPPPSRRHLTPLVTVNPPQALHHRHTQQHLQHDCAPLSAVAASTPYSPLQSPRTLSPCVNVKATSLSHRRRSSTSSSNAAPSIMNEGGGTSEAGLTPPPEGRLLVSAYIVPANKGRTPFQLRREFDLQELLDAVPRPPTDRRRLSSVNILASPIVGPPRSPLSALPSSANSAPPAALPSTPVTAGGGNATNYKTGMKRPASDHSPNTPASPHPNLRRQAAGKHSRQASQKDLAPPDQFQADGGVLIPIRPHPSLGSLPALAAIILSRRVDAGDVVELPLPHPEFWPQTASYVYRSRGELTDEVRQNIEHLGGKCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDL1</accession>
    <name>A0ABR3ZDL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PRS4</name>
        <name evidence="13" type="ORF">Sste5346_003750</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002320">
        <property type="entry name" value="PRK01259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="12">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="324" mass="34931" checksum="486B2CFCCB5C9DFF" modified="2025-10-08" version="1">MGDTANEIKLLSGNSHPMLTRLVADRLGIEPAKTLSLNYSNQETSVTIGESVRDEDVFILQSTAPGDINDGLMELLIMIHACRTASARRITAVVPNFPYARQDKKDKSRAPISAKLIANMLETAGCSHVITMDLHASQIQGFFSVPVDNLYAEPSVLRFIRENPNLQRDETVIVSPDAGGAKRATSIADGLEMAFALIHKERPRPNVVGRMVLVGDVQGKVAILVDDMADTCGTLAKAAATLKEHGAREVIAIVTHGILSGGAVDTINKSCLSQVVVTNTVPLGDKQERCPKIKVIDVSSTIAESIRRTHNGESVSYLFRNVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDR0</accession>
    <name>A0ABR3ZDR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045477732" evidence="2">
        <location>
            <begin position="21"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="322" mass="29403" checksum="706C579FE6FCDE91" modified="2025-10-08" version="1">MKISCLLVLALAWASDVAVASPCKPKPPPSSTSSPIAESLSSGSSSAPSVSVSFTPSGSSIAPSSSSSVSGADGAGAGGTSLSSSLSVSASSPLSSIVSSIVSPSSSVSPVSSSSVFSPSSSSFSTTYVLPSSSKPASSRFSPPYANHSSSAVSFSIHSSVIPPSASASLSSSLPASSAASSASSSSVSGADGAGAGGTSLSSGSSTSSASKSSVSQSSVASVGSAVSGSSSLVVSSSGSASSVASSGSSVSSASSISAASSGPSVSSAPSASAGSSSASSVSGSSASSVSSASSASASSSASNGSGSSPLGLGLIWLVVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE79</accession>
    <name>A0ABR3ZE79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="404"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="219"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="46883" checksum="75D69B5B07B65C52" modified="2025-10-08" version="1">MFPSVRRVVASSSAAPPAAAVLVRSGHWSAPSTAASVGQIQPGQTIHQCRSQQPQQRRYSSSKPSSPDNGSKALPGVPSTPSNSTSSSSSSSNSSSSFKRKRKAKQDASRPSVQKLPSVPSTQHLPVESLALSTFFSQHRPISITHSLPKVVTEDAFAAIFAPRAGSGRGKSSEVIRTLSRAVNDLEGPMAGLSVNDNASSTTTQPAQRGSRARQAKEQAQFARQQLQQQLEDDAAAAAANESSNANSSSQLEFKNADGSDAGIYVQLNALSGQFLPFQPPPAPVPEMTEAEASAAAEASAETSSSSNAPGTITFELDGGELSSTGNSAAALDEDAEPRSTRVFKAILTIEEQLDENGEVRIVAHSPQILEEGAEEALQRPHGLRRHRLPSAYHDGTSGMPRMEAISVRRQRKLRMKKKKYKKLMKRTRVLRRKLDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF88</accession>
    <name>A0ABR3ZF88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytomegalovirus gH-receptor family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="883"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="412"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1004" mass="109996" checksum="DDF11E00DBE68481" modified="2025-10-08" version="1">MPPAPQGLSEGDANARRPSRAHLDKGGLTVNVDSVFQLPSPSPSPIEPPVEFPNDKDAKTSVPPSTTTDMTEKPVVSPSIGTPKITSPSHPSGVRRLSASKMAELTESLPIAALPDDAELVMGSLAARSGFSPPLDNQPMAQFPRADVRNGDASEVTPVNAHVDEQPQRVQRHWNSTGSLRTLSTPPISRRKSAATQQQQQLQQQPLQQQPQAAVPPVASNTSTRRHSHNTAPRLPPLHIDSGKAGVGAGPGTGPAATTALRPGPQLGQKGDLSAHTPNHGEQRLPSPIPPSIPLPPMSLPTLLQLELAGQRPSPLYIHHSYTSDIPYESHAVKFERLKNFLLLPTYLERTMYFGALACLDAWLCTLTILPLRFCIAVSVLVRWWGYVLWKEVRWMTAYVWRGLGRMWRRGRQPKPSKVGASTTSTDPALTTTTGRPRGRSNGSSMSDSAGPALDGQPRPRRHVQTSGTGVTMDAPAASTARRKIWGHRRTKSMPSNLTSFHKADLLQGAVIVCSSLALMNLDASRMYHFVRAQSAVKLYVIYNLVEVGDRLLSALGQDIFECLFSSETLSRTASGRSKILLPFGMFCLSLVYNIAHTMVLFYQVITLNVAVNSYSNALLSLLMSNQFVEVKSSVFKRTEKENTFQLACADIVERFQLWIVLFIIALRNVVEIGGLSVPGAGIDLGGSSGGMLEDMAAKVPLHNASILPASFKILPSWLTSIEVLSPFLIVIGSEMIVDWIKHGYINKFNNIKPNFYSRILDILCKDYYTNAFVAPALMRRLGLPLIPLCTLFIRSSVQTYHMFLATHLPSPLPPSTHTSLVAEAATPSSPAIAASLERLDLLIRNALGRAVHGNPYASMGGDAAAAASTSGSWTWWWSSDDLIAGVTMVVVFFLMFLILLIAKLLLGMALLRYARNRYTNMKVQEHAEAMGQAEPESFDATGKRTGGYGKVEVGEERRRWIFSDDPEGLKKVREKDRRESGKGKKEMDLNTITRYEMVAKRIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFM1</accession>
    <name>A0ABR3ZFM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chromosome condensation complex Condensin, subunit G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">YCG1</name>
        <name evidence="10" type="ORF">Sste5346_002899</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="636"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="589"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="598"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1066" mass="118039" checksum="1CD6787BAE9945E5" modified="2025-10-08" version="1">MPTRTSRTSRVSSALSHKTSSTTLGRPSAASRASSVNLDIPAEPEDNALRAKIAPVFREAQKNTASHRKLAVTLRKIQEACCYEPTSVKASAAVSTDFHEDDFNEEFVRCVYRVMPVKKSEPVGDKVIRFIGLFLRHAIEKDNELLGEVDEDASTMPETPGTRLTGFLVDKVLLLLVAKDKYVRYRATQLISHIVNSLDAIDDDLFQKLRSGLLRRIRDKEAMVRAQAVLGLGRLAGNSVEEGQDSDDSEGGAAAIGLLDKLLEVLQNDPSADVRRSLLVNLPILPNTLPYLLERARDSDAATRRAVYSRLLPALGDFRHLSLSMREKLLRWGLRDRDENVRKAAGRLFRERWIEDCAGQPEENEDGQPAEPAAPSFDGLLELLERIDVVNSGVEEGVALEAMQGFWEGRPDYRDAVNFDDTFWETLSAESVFMARSFNDFCRSDDKYEYLVEEKLPEVTKLAFYLERYIKVLVDAIKRAEEKEVGEDEEEEEEDTVEQEFIVEQLLHIALTLDYSDEVGRRKMFALLRQSLSISDLPDEVTKLTVNVLRDICAPGAAGEREFCSIVLEAVADVHDTILDDVDTNEVAEDDSFHSARSEVSSDTTPTKSRQSSKQPEMTEEEAQAKAIKEIVINLKCLHIVQCMLSNVSGSLQKNDHLVAMLNNLVVPAVRSHEAPVRERGLVCLGLCALLDRSLAEENLEVFMRFYTKGHTPLQITALHILTDILNVHGAQLLSSNPALLRVYVKALRSGAKAPEVQATATVAVSKLLLGRVVTDQEVAFELLKTLVVAYFEPSSSTNQGVRQALNYFLPVFCYSRAENQALMQAVSLDALHALFNVREGLEDDDEDVDAEMVSLATIGACLVDWTDPRKCFVPGMSADAEKKNVNADVHLDFAKAILDRLYGNASKEEKKAVAPLLGKLYVSPTSTEEKTRAVYEEVSEAVDSQLLSDATSRNALYKIHVSLGKIVNNLDQAAASHIGGSVMGGRRSMSRATSLGPDDRTVLAGNEDRTIVGQIKEEDEDEGDGVMEELNETDVDADEIGDGTTIQMTTVQVDEDLLTDDLMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG05</accession>
    <name>A0ABR3ZG05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF46">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="488"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="560"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="694"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="744"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="784"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="821"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="882" mass="97832" checksum="1A32F189C5C87207" modified="2025-10-08" version="1">MWPASMVSALQWFAFWSFAGLLTVPWLFCVYQIVTHQLGRTKRIKQVLDEVSAPKVVVVMPCYREEPEVLITAVNSVVECDYPPSCIHVFLSFDGDQEDELYLNTIERLGVPLTLESYPKSIDVSYRSARVTVSRFPHGGKRHCQKSTFKLIDRVYQQYLKRNDNLFILFIDSDCILDRVCLQNFVYDMELSPGNRRDMLAMTGVITSTTQRHSLITLLQDMEYVHGQLFERTVESGCGAVTCLPGALTMLRFSAFRRMAKYYFADKAEQCEDLFDFAKCHLGEDRWLTHLFMIGAKKRYQIQMCTSAFCKTEAVQTVKSLIKQRRRWFLGFITNEVCMLTDWRLWKRYPILILVRFMQNTIRTTALLFFIMVLALMTTSKKIADLPVGFIAVSLGLNWIMMIYFGFKLRRFKIMLYPLMFILNPFFNWYYMVYGIFTAGQRTWGGPRADAAAADGEKTTVQEAIEQAEEQGDDLNIVPETFLPAAEVQRQKSGKRLPGADGKSSAGPTAAGSRRTDAAAIAAIGGAGVTKATANVSQFGRPDAAGEGSYFDRKDAAHDGYPSSAGQHATANVGATVGRSKSGRVMLQPPDKIDGMFSAPERSSTGWYHYPDDSLISLNLLGQSSPSLLNNNGNYIGNRGRNSPFMTLHPRDSFESFMSNNTNPGGGGGGHNNSVYMPRRVESLMSDEDRRKYEMAQASQLSFPGTSSAAGHHQPLGMPSPGQVYEYRSDAEMQQAGFYTDTEVAANPSSSDNIHGGHREVTSHHLAPRRPDHRRLASNDSIGSRHSASRSVSAASSPDLQPQPSMSAMPPHSLLSGGGSNYTQAGSGSTVRPSPLGRLSYIARSPSSEEERGGGAEEDAADNGSKQQVHLSPPSPGYGRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGB3</accession>
    <name>A0ABR3ZGB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thermotolerance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1068" mass="117750" checksum="A19222011271F4E4" modified="2025-10-08" version="1">MEIQTDVLRDGEWVTETVTIDDVLKAKNNNTSNNKDPVPEPRPDQPPNLGILTRTVVESPVAHWMLPVRLRSAQHMDVAVIGDHYVQISELGRDGRLRNIVRKTDFGSRIRNAKVIGTPPESATDEEKDDAEVRIKMEDDDAMLGSGDADSISGDETMEDALNLPAEFDDFAMEVHETSRFHHGRGIPYWAAWTRPYRLPTYNTTRDSIYLAREDGVVMFLDINSDNILGASVEIGKFECNIGTAFCSLFDDFNDILIMGGDSGPGTIWQIRPRQPNMQLGKIPNWSPVVDLVTTDEFSTVNGLIGANGKKIEAKSHGANNVSNPHYSNPDRIFGTSGRGVTGAITEFRYGLRADVGLEVDYLVPVKQSWIFATRTEDYDIEFQVLISLIDKSEAFYLSADLSQVGIHEEGTTLYDLESRTLVAAQPQNKSVLIDPGSDDFSRYLQGQGSSFANRSFESISSVAFLPQHGNKATIVFGTRAGDLVTLILGETGFLAANVERIGPSRVDLVIIDDVQLGKAVLATCNGQVSVHYGSGEKAATFRSSHTVWPFDAAALNKPAPFVNSVTVLSGGLPGRQNKTQLVLSSTSHFMLAELHPQPGPVQRSLPLNGTPAKVLYSHTLGCLVVALKDLENRTTLQFINPDTGEDLSMPTDKNREPAEFISGLGKVGDQILSLGEWNYERQGDKWVFLFVCTKEGRFLVISTARTTIDQQSKVQYWTRYKKSMHEPVHSVVSRGEYVFSCVGSTIYWDKLDPELKRLVTCGTFELNSCATSLRIVNHKLVAVTDDDGSVEIIDISEGSKPGEMTLYHGDSEQRSATHMIEIGSKISGNELDTSLLLVCGRDSTASGLWVPWQQPGKDCWAVFEADLPASVRKLVRGRTRPSWQQARRDVQYGLLPSTPDEAEILGVCLDGSLQHFTLLSLPAWRLLRLVHDLALTSEKLFPFTYEANDDDDDYETDPGAGDRTVMHIDGDMLQRCFDKRALEELFAKPSRSAKLYAALEKLDGGALTAGFDRLQGPAQNAGAYSEMTDGDGEGAASGTNGTVLDERTHRCIKLLYSILEYYLQPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGI8</accession>
    <name>A0ABR3ZGI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PTC2</name>
        <name evidence="13" type="ORF">Sste5346_002694</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="375"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="452" mass="48818" checksum="4930344A91F24D8E" modified="2025-10-08" version="1">MGQTLSEPIVDKSSDKGEDDRLLYGVSAMQGWRISMEDAHTTVLDLLANFPFAQKSHTSKISFFGVYDGHGGDKVALFAGENVHKIVAKQEAFKKSNYEQALKDGFLATDRAILNDPRYEEEVSGCTACVGLITDNKIYCANAGDSRAVLGVKGRAKPLSFDHKPQNDGEKARIVAAGGFVDFGRVNGNLALSRAIGDFEFKKSAELSPELQIVTAYPDVTVHDLTDNDEFLVIACDGIWDCQSSQAVVEFVRRGIAAKQDLDKICENMMDNCLASNSETGGVGCDNMTMSIIGILRGKTKEEWYDEIAKRVADGDGPCAPPEYAEFRGPGVHHNFDDSDSGYDVETDHRQQSFGVGGHRGRIIFLGDGSEVLTESDDTEMFDREDKDLDSQVSKASASSDDEKEEAKEDGADSKAEGAPEVKAEDASSDAKTTEAAKPAETEAAAADASDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH94</accession>
    <name>A0ABR3ZH94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="22695" checksum="71367A1C25982FCC" modified="2025-10-08" version="1">MIIGDGEAEAADGLACDIEGDEDTADDGADEGDGDDEGAGDGDEDGAEVGTEEGADDGEEDGRDGVDDGEDGGTEDETDGVEEGAEEGVDDGEGDGEDDGADEGTENADEGAEDGAEDGDEEKDDDGADEPEDEPEADDEGTDEGTGEAELGTELEPEAEADLELTIELELSIGDTNSTDDADKIDDIEDGPLLLLLDLLGRQAEASTPPKSHRAATAPARML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHH0</accession>
    <name>A0ABR3ZHH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_002885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="489" mass="52583" checksum="E60FC4EE2BE348E0" modified="2025-10-08" version="1">MAPPKSAYEFIDFVNESPTPYHAVASAVSRLEKAGFRAIKERDDWSFSLKPGGKYYITRNGSSIVAFAVGAKWRPGNPVAMIGAHTDSPCLRLKPVSRKSNVGFLQVGVETYGGGIWHSWFDRDLSVAGRVLVRTSDGNIVQKLIKVERPILRIPTLAIHLDRSSDFNPNKETELFPIAGLVSAELNKTAADAASIVTDSDDSASSAAAATAPLQPMTERHHPVLIDIIAKEAGVTADDVADFELVLYDTQKSCLGGLHEEFIFSPRLDNLGMTYCSVMGLISSVAPAGSLDDESAIRLISCFDHEEIGSLSAQGANSNLLPAILRRLSVVPAASTASSEPVSTTAFEQTCSTSFLVSADMAHSVHPNYAGKYESNHHPLINKGTVIKVNANQRYVTNSPGIVLLQETARAAGVPLQLFVVRNDSSCGSTIGPMLSAKLGVRTLDLGNPQLSMHSIRETGGAYDVEYGIKLFSTFFDHYSSLEAKILVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHV9</accession>
    <name>A0ABR3ZHV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Autophagy-related protein 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATG13</name>
        <name evidence="7" type="ORF">Sste5346_002643</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ATG13 family. Fungi subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040182">
        <property type="entry name" value="ATG13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018731">
        <property type="entry name" value="Atg13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430:SF4">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10033">
        <property type="entry name" value="ATG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 13 N-terminal" evidence="6">
        <location>
            <begin position="80"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="394"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="483"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="753"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="837"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="926"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="988"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="487"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="667"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="753"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="776"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="851"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1047"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1092"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1113"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1147"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1165" mass="121063" checksum="2139F34CA0066FC4" modified="2025-10-08" version="1">MHQQSRPPRGGYSPATQPQTNPTRTNNPRDALASRSRATSEAAPPGPSLDGGGDSGVSSATGLASGGPTKESIKKLDQIIQNFHLKAAVLVAQARIPTTPSGGGRGRKTNKWFQIETEDIDDFKDELKVWKHCGGFEHRPPPMVIETYLDASRLATGQALVVIDENGKRWDALEALNSSDLSASGSGSSSSGRSDSNKIRTRSTEIILERWKIELQCIPSLLKSSTGGAGGSGSSSVADAAGEKGRAGDASGSASGSGVVDYDIEDFGPILPTIYKRSIVFFRSLFVTTHVLPAYRFSRQASTKGVHPALKVRCRILTGAEAEARIASRGFDNLRQPLVYDISRDAVTDYMFGDLEVPIGRFSASVTYRNDCSFRIDDSESLLSSRFMGIDENYFRPSLPPSQRPDNTYLSQQRQTQQSSAQQHRRRESSAEVVGSLPSHQRSSRNVAEPAYRPQPQQTYGSLNTFHGADALGTSPISALKAVRTAGSDTSSPTNSYRPSSMEQRPQIDPPNSLPITGGRAAGLSPTSSVSRPNVLRNLDGLGRRTSVSFQPFKAGSLSGSPRTTQDELPLPSSPLSGSRPTSGLSALAQARNRSSLTAGMAASLRGAPQPSTSVGSPSAAMAAAMMDPGQASSPRLAGGSRFSSSFTHRRGRSSFGGASRNEDDQGSSGKQSLASSMAQPGSGLLAEVGGVASSGSFQTDDDNISEFLKALESKKTLQSFETSSKRGESARRTAAQLSRFQLMRESNVALTDSMNSSVQMPRSLSSSSRQLIAPGTSGASSTTGNAAGAAAAGNTSTSLSPSSHSPIKPMSPNTPHTPHTPAVPSRLSENAIIDHQGQVRTRPGGPRPIGGKDDENNVNHDDDEEDGNNQDVAGGTNAIDIPLSPRLLQLGGRRSSSAVQKTRAVHHVDDDSAELAAFAQRSLSVGGAGNREPPPPGALFRLDDHTSAGDDAGDDAASREGATSGGVAGSPAGLKAAAAGILRPASGSALSRSAGVRDDADTSLPPVTSSVGAALRSSNTAGGGSTLSASPRRRYMSRHQPSPAPSTQQQTQSTSQQQQQQQGGDASSGLRGSVGSEGPRGSINSSFLGRYSGGGGSGRGSGAGSVASGLVGNLGGAGATGSGGNSASGGGYGEADDEPLVFDLSELGRDPNRQSIDESRRRQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI06</accession>
    <name>A0ABR3ZI06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpl8</name>
        <name evidence="7" type="ORF">Sste5346_002713</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="121"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="262" mass="29425" checksum="69C6D517E16849AC" modified="2025-10-08" version="1">MAPKATGKKAAPAPFPQSRAGKKAPKNPLIEKRPKNYGIGQDIQPRRNLSRMVKWPEYVRQQRQKKILSLRLKVPPALAQFQHVLDRNTAAQALKLLNKYRPETKAEKKERLLKEATAIKEGKKKEDVSKKPYTVKYGLNHVVGLVENKKASLVLIPNDVDPIELVVFLPALCRKMGVPYAIIKGKARLGTVVHKKTAAVLALTEVRSEDKTELSKLVSAVKDGYLEKNEEARKRWGGGIMGEKANKRIEKKRKAFESAIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIP0</accession>
    <name>A0ABR3ZIP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small subunit ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="17877" checksum="887A8D86C91CDC55" modified="2025-10-08" version="1">MGILHLINTCSHLQNASKARLGLTSIPSNKFNLNFVLALHREGFISSVTRAGPTPPDPAAVLTGTHIDEVVTTANVASRRLWLGLKYWNNEPVMRKLKMYSKPSRIVRMPLEDLEKVARGFPVGMVKGLTLGECLFLSTDRGIIEVREALAKKIGGQVLCVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIU8</accession>
    <name>A0ABR3ZIU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="444" mass="43731" checksum="2C4D91282EC72816" modified="2025-10-08" version="1">MIVTTMKVPTIVTDMPTDTLPDYDYPGPTDEPHYTISNQPINTNFVINPGGFRDTGIGAPVDTDTPVDTTWIGSTTVSVGIVPSGVVIGTSTIVDAPDGSAQTVVVDGITYTIDPTQIYGLGSYVNRPSWSNSFNNYNPFIIPAVIVTSSISGVLAGLPVQVSSNTIEVDGTPFSIPLQPSVATVHGSVTVHLGPDGVVAGGETFSMSPVVISAAPGSNGNAAVGGGGGSEIVVAGGTVLTIDDTNVVVGGHSIAYNAVAGALSTSTVLTVAGDAITIVPASNNKGGSGSNGGHGGVFIVVHGTTMAAPVHGSTHYELVGGATFTEVSPSVIVLDGHSYTIGPAVAAATGGLAAAVAAPGATPTTVVVGGETVTIGPGGVTVGGTLTFRYPFVATPAVTLTGMATITGTAAMRPGAVGGLQSNTMPTATSMPQNVGGFGAADSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ67</accession>
    <name>A0ABR3ZJ67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="244" mass="26122" checksum="2A7BEB1617F9AA70" modified="2025-10-08" version="1">MAGAEVPLSYFCAAGALITSNGWLDVLLWGSTRRSIVFGDVGEENVGISTFTFMRTPPNRRFGNMVWVEGGVNGSSNGNGNRNSKTKRRELSKHGSSRDSSNTNSHMGTSNNSRSSSRDRGREIPLGVAGGIFGRGETMRGVRDRIMRGPRGWRELGSKGLGVSGPGVGNSGDSVNRSVAASQESLQRLGESSSTGGVLAIQMEMETSVVVEIEDIPQRVSRSRAPSTSMPAYYDKDMPYLPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA4</accession>
    <name>A0ABR3ZJA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CMD1</name>
        <name evidence="5" type="ORF">Sste5346_002583</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="149" mass="17025" checksum="380C05714C895A98" modified="2025-10-08" version="1">MAESLTEEQVSEFKEAFSLFDKDGDGQITTKELGTVMRSLGQNPSESELQDMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDEEVDEMIREADQDGDGRIDYNEFVQLMMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJT4</accession>
    <name>A0ABR3ZJT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF1">
        <property type="entry name" value="AROMATIC RING-OPENING DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G00640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="4"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="27215" checksum="F4D8ECE6F575760D" modified="2025-10-08" version="1">MGAHWEAMGDRIEVAMNPNPGKNPVAYVAKEKYEKFKLTADLPMGNRVIGMLRDSGLDAHPNPDFDFIHDTYLVLIRMFPKQKTNIPVVIVSANARMDPHLHTRIGAVIRPLRYEDVLIIGSGGAVHNLYRNNWMQMVLWRDNLAMPFAPQDCMLEFRQAVYDAFTMNRGPAVRRAVTRLMKHPLFRQAHGTDEHFIPACYVAGAAGDKEDKEMDNVFLGECWELVNMANSQFQLGSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK12</accession>
    <name>A0ABR3ZK12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="69981" checksum="92BE2AED73A9A0C6" modified="2025-10-08" version="1">MLPDLRPPGPPPPPPPQSSSSLISSSNSVADLGAYCGVPQALLWELLDIYFTHAYNASLLLHKDTFVHSLRAGTVTPHVLLSVCAWASKFYKDESGNYSLVKPGFGHEWAARAGSLVFAELVDPSEENIVTFINLSLYWYSVGEWRRCYLLKWNAILISYNLNITSAARDEAARDEAQPAMLAVEMSRRRFWSSYLSMNFGSRVEFSTGNYSTAFAKVPLPCADAFFASGMKDLDKKGEGSVYAELVRGLTLWNKISDMVKKTDVPKLATLDSLHESLCQWWSNVPNSLKLPLELPLAGETRTQDVDKDAPSSKSQQSPLPLRLLLCVMYHQSICILHSSIVPLFSYRSDSATTAASSSHSHLSLYSRHVSAQLAFEHAQAVSQLLKLSQRHYNIDADRIPGFVSFAAYSACAVQIPFFWCSNQDVQTRARSNVLMNLRMIQQMGKHWKYVSLLGINSWTLYKTLSRKPPRLTDEPKFMDPSMLDVSWNGTDRAAKSIMSYSEIIWQSTGSYVERTDAEITDLGLSSRSRPSSVPPADDELSSSTVTTVASTFGGADGHGGNGSSNGGMNAAGLYLSPPRFDTSLEFFMPSSPNDGFDFVEAQNGMISSQQLASFNTWLQQIESEMLFRSPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL33</accession>
    <name>A0ABR3ZL33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF1">
        <property type="entry name" value="ISOCHORISMATASE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="31"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="228" mass="24224" checksum="030A0FE63825D099" modified="2025-10-08" version="1">MATLSLDSHPRHAAYRDAGFGQRLGWGRRPALLLIDVCAAYWKPGSPLDLSHNPEGRASVDAMARLVTAARTAGIPVVWAQVRYNHPTLVDGAVQAKKTKTIQAWQDGDTRGLDAPPLQHTDILTPAMGDTVVLKRNPSAFFGTTLATELHLLGVDTVVVCGVSTSGCVRATALDAACSGFRPMVVGEACGDRSPLIQQQNLFDMDASFADVVSEAEAVGEMSRGCQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLT1</accession>
    <name>A0ABR3ZLT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasma membrane low glucose sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SNF3_1</name>
        <name evidence="8" type="ORF">Sste5346_002176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="118" mass="12489" checksum="56056D707214BD49" modified="2025-10-08" version="1">MPAFTKRYGKYNAATDTYSISAPLQSAGSFLPTAGLVIGALLCFAISDRIGRRGAMIATSIMYLIAIIIEVTSNSYAQIVVSRFLNSIPQGMSASLLPAYQSECSPASCHVALVGLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP91</accession>
    <name>A0ABR3ZP91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">D-lactate ferricytochrome c oxidoreductase</fullName>
            <ecNumber evidence="9">1.1.99.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DLD2</name>
        <name evidence="9" type="ORF">Sste5346_000965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.40" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="133"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="589" mass="64340" checksum="FC62589650714041" modified="2025-10-08" version="1">MAFKAQVGSVLRKTAAPKTAVLRSACTARTATPASSTFRTASKTTATAATATRSFSTTPARSWRPTQARRADITRTSERYPDLKRDSRFAALTREHVAYFKELLGENGVIDAVTDPASQDDVEPFNGDWMRKYRGHGQLVLRPGSTEEISKVLKYCNDQRLAVVPQGGNTGLVGGSVPVFDEVVLSMGRMQTIRSFDDVSGTLVVDAGVVLEVADAYLAERGYLFPLDLGAKGSCHIGGNISTNAGGLRLLRYGSLHGTVLGVEAVLPDGTIVDDLCKLRKNNTGYDLKQLFIGAEGTLGVVTGVSIACPQRPAAVNVAFLGLSSYEQALKAFREAKSQLSEILSAFELMDAGSQQIVRTVRPDARRPLDGEHDFYCLIETSGSNAEHDTAKLEAFLEDVMGKEIVEDGVVAQDETQVKALWTWREGITECLGHLGGVYKYDVSIPLPELYKLVEDTRVQLESKGLIGDGDEFPAAQVVGYGHMGDANLHLNIAVRRYDSEVEKALEPFVYEWIAKRQGSISAEHGLGIAKKKYIGYSRNDTLVGLMKQIKNTFDPVSNLPVLVPSFPFLSFWFFSLPFTSLPSFFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPC3</accession>
    <name>A0ABR3ZPC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA polymerase</fullName>
            <ecNumber evidence="14">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">POL1</name>
        <name evidence="20" type="ORF">Sste5346_001000</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="14"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05776">
        <property type="entry name" value="DNA_polB_alpha_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05532">
        <property type="entry name" value="POLBc_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3200.20">
        <property type="entry name" value="DNA Polymerase alpha, zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024647">
        <property type="entry name" value="DNA_pol_a_cat_su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038256">
        <property type="entry name" value="Pol_alpha_znc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045846">
        <property type="entry name" value="POLBc_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015088">
        <property type="entry name" value="Znf_DNA-dir_DNA_pol_B_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861:SF1">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12254">
        <property type="entry name" value="DNA_pol_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08996">
        <property type="entry name" value="zf-DNA_Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase alpha catalytic subunit N-terminal" evidence="19">
        <location>
            <begin position="12"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="17">
        <location>
            <begin position="499"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="16">
        <location>
            <begin position="813"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger DNA-directed DNA polymerase family B alpha" evidence="18">
        <location>
            <begin position="1315"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="54"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="157"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="847"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1287"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="1293"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1902558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1540" mass="170897" checksum="0F0868A567E160F1" modified="2025-10-08" version="1">MSKARERRSKFEGLRALRKSGKTAFNTFEVNDDNALYEEVDENQYKNIVRERLNQDDFVVDDNGEGYADDGREEWDRTHVYESDSEDDVGGGLVGRPKGRGSKKAREEDQAERDAKDRNIAEYFTKGATKAQPKSKITKTEDDDEFMSNLLGEVHANISPALPRMPKKRVSDQHLPMADVTRQPKRVRIADTLPVPGGHHNNNDDEDDGLTPIIHSDAVPPSDDIPMSDPMPSSPTVRVASRKVQPAAAPVEQDPPTATSNDKDTKSKDDEEEEDTMMEVAHTGAVNAASVNLAAARPVKKILKTPAPYPSPANSSPAPRSQETAAALDPTAWTNLNQKLNVMSSPQSADAVTFTGGKINYQDAVEEDGSLQFFWTDYTEAANSLCLFGKVFNKKTKKHVSCFIKVDNVERKLFFLPRETRFVNGVQTDETVNMGDVYSEVDGLMGQLGVKQHRSKPCTRKYAFELPGIPKEGRYLKVLYPYTNRPLSEANNSGETYSHVFGANTSLFEQFVLWKNIMGPCWLKIEDADFSSINNASHCKLEVQVAHPNMVSVLAEAEAPEVPPLTLMSLAMRMVYDPQSKKQEVLAISARTYENVGLSDTTPADKLPCRTFTVIRAHGNAFPVGFDTLAKSRGRGTIKLVGSEAEILSYFLAQLANVDPDVIVGHQLEGVDYSVLIDRLRSRKTPQWSRLGRFRRQQWPGNINRIGGNVFAERQVLSGRLLCDLANDAGRSVMLKCQSWTLTEMCNLYLGGEENQRRDVDNDAALNTWAKTPNGLLDYVAHIEADTYFIAALALRVQILPLTKVLTNLAGNSWARTLTGTRAERNEYILLHEFHRNKYICPDKQAFRGRGGREEDEPSNEAGGEAGAGGGKKKDKYKGGLVFEPERGLYDKFVLVMDFNSLYPSIIQEYNICFTTVERSALASEDEEEAVPEVPKEQEQGILPKLIAGLVSRRRQVKSLMKSKTATPEQLATWDIRQLALKLTANSMYGCLGYTKSRFYARPLAVLVTYKGREILRSTKDLAESKSLQVIYGDTDSVMINANVDDVAGALRVGQEFKKAVNDRYKLLEIDIDNIFRRILLQAKKKYAAINMIETGGKYIEKMEVKGLDMRRREYCALSKEMSTRILNEILSGNETEVSVTRVHEYLREMAAKMRSGDHTPTNGVPANKYTIFTQLGKDPTDYPNADSMPQVQVALREASRGKKMRKGDVVSYIIATGENAPSSEPAPKRAYSPGDLLKKDSGLSPDVEWYIAKQIFPPVERLCANIVGTSTAQLAENLGLDMRRYGNNNGQAGSGSGGSGGNGVDELEIHPLETQIPDEIRFSDCARLQLRCRKCKTSGLFEGLSATPSQEPPAEGAPRPVKVTPAGIACGTCETTLSTLSVVAQMEHAVRLATTRYYEGWLVCDDASCGNRTRQMSVYGARCLGPKGLARDCLGRMRYEVGERDIYNQLLYFASLFDVDKARDNVKNAVAGSNKAVPLPDQERILALAEHNRVRFGTVKAVVERYLDKCGRRWVAMDTLFAKLGFAAGAMAIVKKEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPM1</accession>
    <name>A0ABR3ZPM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA cross-link repair protein PSO2/SNM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pso2</name>
        <name evidence="8" type="ORF">Sste5346_001501</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="706"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="918" mass="98915" checksum="C8145A8AF8844884" modified="2025-10-08" version="1">MPTPTRTRVAPRPGAGQKQKTMTSTTPKTQSKLGFSPASVRNKMAGPPPPKGPPNKSILSFFKKVPPPEESMFVAGSAEAAAVLKQLAASQGQGNEENNVPAMEETDVEIIDDSRFNECKGPVKRRRLSEEQPTKAVQRGPFVDDSDEDEDDEKSQKNESLPAPILNNEEAITLSPRRTETYSSFDETFVKVATKTETTEQTINFGDNDFEADFADFADLDDDDDFAYAGEEFRERKYMEAQARLEADAAAMVAEDADGGSSGDGVADGCPICGTSLAGKTSDQATVHVNACLDGLTGCSSTEAAPPPPPAEPTKTTPTPPTTEPKPTTTISGLSKRFMRTAQPRPGQANPVAFGGPGSSSSNGLGSAFAKLMSGHAEDEAWTTAAASEVASRGKPAYERTCPFYKIMPGFSICVDAFRYGAVEGCRAYFLSHFHSDHYIGLTAKWCHGPIYCSKVTASLVRSQLGTAAQYVVALDFEETVDVPGIPDVRVTMIPANHCPGSSLFLFEKTMQPTGRVHRILHCGDFRACRAHVEHPLLMPDVLDKKLGNGKKRQQRIDVCYLDTTYLNPRYSFPPQDDVVKACATLCATLDQSLRAGEEGEWDKALRRREAGGGDGSGNVKDFFKRANSTNDPVVEEPLVVSPPRDALAVLGQRPPTRDRKRLLVVCGTYSIGKERICKAIAQALGSKIYASPAKIKIVSQLGDPELTALMTSDATEAQVHMQMLMELRAETLAEYLEGYKGHFSRIVGFRPSGWNYRPSLASGAAAPGAQGSGGAAAKGAAAAAATPSASLSPSTLATITLLHGAGWRTRFGVRDLVPQRGSTQEAICLGVPYSEHSSFRELAIFLMSLRIDKVVPTVNVGSDVSRKRMKAWIDRWLAERRRGGVVQTLSEGDQNIKAGKEGKLWEGKDGQGGVAYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPQ4</accession>
    <name>A0ABR3ZPQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GCN5_1</name>
        <name evidence="16" type="ORF">Sste5346_001122</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="160"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="405"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1902680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="500" mass="56172" checksum="DAAE5CC3C1537A15" modified="2025-10-08" version="1">MDPSDLETADAVPKAEDNTKRKASEDPTSPTEAKRIKRSDSSEAADNVNEVADSTEPAVAGTETKATSADNDDNDKNETKDAPKAEAGAINGDEAMETDEKKENGEGSGEADKNGDTKDETNGTAADNDSLEKKPLTKAEMKPIPFPEKPAVIEERTGEIEFRVVNNDGAKDSFVILTGLKCIFQKQLPKMPKDYIARLVYDRTHLSIAIVKKPLEVVGGITYRPFRDRKFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATSPVMHFLTYADNYAIGYFKKQGFTKEVTLDKSIWMGYIKDYEGGTIMQCSMLPRIRYLEMGRMLLKQRECVQAKVRAFSKSHIVHQPPKEWKPGTDGVQPIDPLTVEAISASGWSSDMDELARQPRHGPNYNQLLHLLNDLQNHQSAWPFLIPVSRDDVADYYEVIKEPMDLSTMESKLEADQYATPEDFIHDAKLIFTNCRKYNSDNTPYTKSANKLEKFMWQQIKAIPEWSHLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ50</accession>
    <name>A0ABR3ZQ50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="877"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="928" mass="100424" checksum="5B05982D2D962F31" modified="2025-10-08" version="1">MPPSDNAPPPFESIQSLPPAASSLRNPKMRQTSHGPLGHPGGGGGDLPIRARPLPLSQSEASLPVRRGTPNSAAASLYASTLTPPGSRSMSPVGGVRAGSPATGRTLSMTSNASIATATSNSSATTITAASSQRPNSSSSAAASIPGAVYTRSLLDLPAAENPGDPLNLVLKAFVPHVAVYSSRDTDELAREKGFPNGLWELLRPFGERVAGRVQVRDSNGAPRPWDDFSVRFTKFGDNLETPESAQGIIQPPTSPPPQLAVSRRQRGSSNVSHASSSRGRSRAGTADARSNATSSRIPLVEAIVDKHLTYAESAFSGLPPPPPTPGQGPPPQQQQQYDVDGTSPYYALYLRRMLSGLPVACHETFAHPVACVIAISSRNPAPIQTFQELYRDISQGDRRLPPWVDGDFLRYYVLVHDEENGDIVQSMALFEKMKRSLGLHCHLLRLRSTQSAETDDDSLLLPRSDWMTAVEEYADLVRSEAFDGETSGDDDASEGEKEDDIIDDPTTRYIFESDATAIRTFVREMVTQSILPTMERSVSLWNDQVASKRKGLSGRFMSLSKRWAGFGSSNSNNNSSGGRGDNGSSNYDAVRGYYGAEASEAILRKLADYAFMLRDWKLAMSTYDILRTDYTNDKAWKYHAAANEMCALSLLIMPPSLSSRTKLDSISSMLEQSFYSYHTRCGSAYGATRVVSLSLELERLRGGAFVDEAVKWGMRLLEARLVGNVGDALLRERMAVCCATRAGRGSLGWGTWRRKSAFWSVLAAEAWVHQAKYIQAQRCLNEARRMYSMLQSDDGINGFIHARDFMAGLQQQLKQGLVVAGEVAEATIAAAEAADVSGDVDLTASTTTAGTAGGPDDTAEPDVDVEEVQLAADETSLKMARRRSRRDSLLGQAGLESAPLRRRRLSAAAEQEDDDGHQEDESGFGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQX5</accession>
    <name>A0ABR3ZQX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 10">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">uba3</name>
        <name evidence="12" type="ORF">Sste5346_000345</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 10"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="11">
        <location>
            <begin position="349"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="435" mass="48053" checksum="7A7661BEE5A38A78" modified="2025-10-08" version="1">MAAAAVETSSERWKYLDRIRASVGPFTPVESGYEAENVIPIIDRMKILVIGAGGLGCEILKNLALSGFKDIHVIDMDTIDISNLNRQFLFRKADVGKSKAEVAAQFVMRRVRGVTITPHNNRIQDFDEDFYMQFQIVVCGLDSIEARRWINATLVSMAESDETGDGVKPLIDGGTEGFKGQSRVILPGITSCIECQLDMHAPRAAVPLCTIASIPRQPEHCIEWAHVIAWDKEKPFPALDKDDPEHITWLYQKALIRANEFNIAGVTYALTQGVVKNIIPAIASTNAVIAASCCNEALKVATSVVPALGVDGNNYMMYSGNESIYTYTFTHEQKPDCPVCSADQKARPLPTDLNMTLGEFLDSFSDRPEAQLKKPSIRAEGKTLYMRSPPSLEEQTRPNLDKTLKELKLEYGYEVAITDPAFPSLSFSFVLAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR13</accession>
    <name>A0ABR3ZR13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">YPO7</name>
        <name evidence="16" type="ORF">Sste5346_001224</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="169"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="557"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="368"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="869"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="377"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="876"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1902248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="891" mass="97907" checksum="15B8070E883E4611" modified="2025-10-08" version="1">MNVTMASPSWASSPFIRDLVDAATDAWHTYRIPILLATFVALVSLRIYLHVTGSADDKEGLLVFPKIYDTATASTDEKKKLQQQEQPSVQEEVKIAVLQQTKTISYPGSANDKKKTSTPAAKKAKPTTATDKAASTSTPKTAAGPRRIKGELPKGGASAAARVPTRIQTIVFYTSITGATAKIVRDYAARLSTTLKELKLSEGADNNVFAPAEVLDIAEVDLDEYFITPPKAAGADATAVDDGSAPTTDYFYLFLVPSYNIDSINDTFLEHLKETHHDFRIDTAPLAPLLGYSVFGFGDREHWPTEDEGFCFQAKELDKWMAKLTGRKRAFPMGVGNTKTDAMVRLTEWSEGVVDVLGLVARTGSLGTGVRGSGDAVETDDEDEDEASDVDDGGDAFDDGSNEDDAEADADNDDVLFGVNAARKANVTRLKKAGVIDDVEDLGRLLQSSKEDDATTGAEDAAEAPGTNVNKAPIAIDFTTYGANGNGNGTANGGPRRVGKKAAAPAPKEMVAKDTPTYKSLTKQGYAIVGSHSGVKICRWTKSALRGRGSCYKYSFYGINSHQCMETTPSLSCSNKCVFCWRHGTNPVGTTWRWVVDPPDLIFNGVKANHYQKIKMMRGVPGVRAERFNEAMRIRHCALSLVGEPIFYPHINEFLGMLHNENISSFLVCNAQHPDQLAALHHVTQLYVSIDASNRETLRKIDRPLHRDFWERFQRCLAILREVRFRQRTVFRLTLVKGFNIDDEVQGYADLVEQALPCFIEVKGVTFCGTSTSAGVGLTMANVPFYHEVVQFVTALEKELQSRGLAYGLAAEHAHSCCVLLASERFKRDGKWHTVIDYDKFFNLLREKGPQGDFTPEDYMGPPTAEWATWGQGGFDPRDQRVDRKGRPIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR47</accession>
    <name>A0ABR3ZR47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF3">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="496"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="211"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="260"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="129"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="648"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="717" mass="77274" checksum="94F57BFBBCAA4E8E" modified="2025-10-08" version="1">MTRNAGAGLPITVFDINHVQVDPTTFNKKRKRTNTACVRCHERKIKCDAGRLSRRSGDIDDGEGILTDQQAHYQATHHVGMHVDGRTRAGPIQAILDNGSNNSDNTRDGNDNDDDNEDDGGGGRGGGSSTNDTSETTQSVSQSASHSASQVASHASHSTQGLPSPSRSLPPPSASASAILLPRLPSPAPRAPADVSVQRFEAYVEDNLGTYAPSFRSSRGGGGGSYDMNMNASGPSESGNNNTSASDAALAAAVLSSFTPSATTHDSHSNSNNDPFLGADASSVSNINPNGGGSNHSVDSTAYTDRNYRSGYASNNNYNNQHTPASYTAIATGSGTGGGGGSGGERVEVEMGTRATLDWEREVTDLDAADVDYLRAKGAFDLPSADLQADLIDAFFSDVHPTSPVVNRWAFLADFRAGRRQSRLLLFAIFTAAARACRNPALLDARGTNHASAWRFYRATKALLDTGYERSRLVVVQALLLITWWWDKKDDGGRNMRSCAVDAINTAQSIGMHRWDQYPRQRDASKANVELGLWKRIWWSCVNRDVGVAVAHGLPCMLSLDDSDVHPLTPHDFNEDPTGAAGGQWASYSEAEVLFMIEQTRVAEALRHIHNQYFVQQKLQLRLTGSIAAREEQLGSSFSRRSTHHYGSHAGHGTTGDAHGVPTSSMPGPVGLRPDNYNDAGLRLCREWLANVPAAVQYDVDDVQGHRFWPAFLHILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR95</accession>
    <name>A0ABR3ZR95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="6">
        <location>
            <begin position="252"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="35972" checksum="01628817790FB4F7" modified="2025-10-08" version="1">MTQSDLEVLLDMGFEKERAELAVKRSGGLQGALTWLEETQDTPLEELKAKSATAAAKEGPDGEMDDDEGATAAAISALESGQAAKSLVCNECGKKFRSQATAEFHASKSGHTDFAESTEEIAPLTEDEKKARLEELRQRLKDKRANQAIADREDQKKNEKIRMKATKETQDMKEELERKERIKEAAKKRAEKVADAEAKKRVKDRIEADKEERRRKAELAKAAREGRAVETPAVPAASTGGLAAAVAASSSSSSSQARLRLQLPTGNVMKTFDAEATLFEVAQALEADDGFKATKFELTFPRKTYEGATDLSKTLRELGLTPSAVLRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRH5</accession>
    <name>A0ABR3ZRH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial dynamin GTPase Msp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MSP1</name>
        <name evidence="10" type="ORF">Sste5346_000933</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF3">
        <property type="entry name" value="FI08533P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="160"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="61"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="383"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="467" mass="50906" checksum="8F3F0C9A0769ED75" modified="2025-10-08" version="1">MSDRKRVGDYVMDLVFFAGMTATAYFLARNILSTFSTHFADPEKEKNDQTRLRAKANLQRLLKSRQGQDGDDEDGEFDGEGGGGADSGGSSRRSGPRPEELELNEYENMIALEVVAPEDISVGFDDIGGLDDIIEELKESVIYPLTMPHLYSHGGSLLSAPSGVLLHGPPGCGKTMLAKALAHESGASFINLHISTMTEKWYGDSNKIVRAVFSLARKLQPAIIFIDEIDAVLGTRRSGEHEASGMVKAEFMTLWDGLTSANSAGVPSRIVVLGATNRMHDIDEAILRRMPKKFPVTLPGLQQRRRILQLVLGDTKRDADFDLEYIAKVTSGMSGSDLKELCRDAAMMPMRETLRSHRASGKKMSAIKAEDVRGLRTDDFFPRSAALPVGPLPPRANKTTAEASETQSYTTTTDDASSSRRRSNNRRSSAASSSAKRKSISGRNGANNDDEYEDVLEDSAIVAPALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS23</accession>
    <name>A0ABR3ZS23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF39">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="45"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="519"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="576"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="600"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="616" mass="68443" checksum="1B92ABE89C777578" modified="2025-10-08" version="1">MDTLLTAEIAANAPRYRRKSSTFIDGIHDVSTDPNHMAPAQLYSTMSGRLFHSGRIAIVMVGLPARGKTLGVKTRIFHLGDYRRATVPGGAVPEDYFFPNATPASIMLRQKILKRCREDIYSWLNHENGQVAIYDAVNPTAAARRALAKEFAKHDVQTLFLESYVDDQRILTENARNVKISSPDFAGMEPDEAAQLYLKRIGAKIPVFETMDEKELNFVKMINAGQKFFYNNVSFNYLSHRIVFYLTNLHIKSRTTFFARAGIAADVTEEEESYRADPPLGPAGQNYAELMSEALLAHREYERQAAAAEAGITDPPPLRPLTVWTSTRLRTVQTADYLKERGYKVRQRSQMSQINPGVCEKLSDRALKALYPEEVELHQLDPYHHRFPRAESYHDLAVRLEPIILELEREQNDLLIIAHESVLRVLYSYLMHCSAMDIPKLKFPRNKIIEIIPAAYQNDAKIIRIPGLNDIPQSQGSSSPDNVFFRHASPLLTFGSGAATSTGGSGAMSPIQGLSSGGLTSPPELLEPFTLPPAGTGAGSASSGTPLQQVMVQSPQNTSQPQSQVTSQPQSRTHSRIQSETVSPATSPSQQQQQWVPERVVNKSKEAVADKVADED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSM8</accession>
    <name>A0ABR3ZSM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RHO3</name>
        <name evidence="5" type="ORF">Sste5346_000082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="134"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="233" mass="25201" checksum="9F53789F0B14B4DA" modified="2025-10-08" version="1">MPLLCGGSKTVQRKLVLLGDGACGKTSLLNVFTRGYFPTVYEPTVFENYVHDIFVDNVHIELSLWDTAGQEEFDRLRSLSYDDTDLIMLCYSVDSKDSLENVESKWVGEIADNCPGVKLVLVALKCDLREGGDEDADDAAAGGAAKTGTDPDSAANDSEINPAGAAGGNATAREKKPMINYDQGLEVARRINAMRYLECSAMRNRGVNEAFTEAARVALSVKKDREGGSCTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSV1</accession>
    <name>A0ABR3ZSV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PHB1</name>
        <name evidence="4" type="ORF">Sste5346_000497</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="275" mass="30378" checksum="32440D1654ADC60E" modified="2025-10-08" version="1">MANALGFIYKMSIPAVAGIAVLQSSIYDVRGGSRAVIFDRLTGVKDQVVSEGTHFLVPWLQRSIIFDVRTKPRNIATTTGSKDMQMVSLTLRVLHRPEVQALPKIYQNLGHDYDERVLPSIGNEVLKSIVAQFDAAELITQREAVSQRIRADLTKRAHEFNIALEDVSITHMTFGKEFTKAVEQKQIAQQDAERARFIVERAEQERQANVIRAEGEAESADTISRAITKSGDGLIQIRKIEASREIAQTLAGNPNVAYIPGGKQGTNILLNAGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTE1</accession>
    <name>A0ABR3ZTE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="32922" checksum="634530119A9F1663" modified="2025-10-08" version="1">MSTTPLTLLPLWSRQEAHQQRWGPTIRGMVGSGLVCCGFVLFRCIYGDDDAWARFLDTMKQRVYTHVQRDADAGEAFVRYVEPALAWTVIEDETTLANATKEQVRERFIAWRDEQLRDTAQHVSVAQAGFYNDLPRFNYCLCVDQACLNSLEVYRTVEDQLGFYEAGLPVTVALVASPWARPYASLADLQKQDKWLGWGVFSSRGQPSDDDEDDEDDEEKAAEDEFPPIESSTSYDVGWMYIEVKTLVGTYDMLHGGDKWEHYYLRPPLVHPRHRFRRPTLYSLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH20</accession>
    <name>A0ABR3YH20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010119</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000114">
        <property type="protein sequence ID" value="KAL1887618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="10"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="57728" checksum="886DDDAC3A10FCD5" modified="2025-10-08" version="1">MASLAHPVIGQVVGKESGHITQFLGIKYASLQDRFAEPQLVSYSGKDLDATKYGPQVVSPPAGVDLELGFIQATLPKPDLPGISDTEGLHLNISVPRQATSIAGTEAFPVLVFIHGGGFAIGGNWWPQYDTAKLVELSLRLGKPIIAVNINYRLGAPGFLTSPEMRAAGYKANNGLRDQRAALSWIKEYIQGFGGDPNNVTVAGESAGGVSTGYLLLDENPAPRRLILLGGTPPLMGQLPVPVADGVAQDVLVSLGCAGIATEDVTKVLLDTPKEDFWVRIPPGYPIFPVIDGDIIRKEVTLASLADQSASVFPGANHVESILVVNSKLDASIMAYSGLMQRKKGIAAAFRASLAKTLDGYSAAVTAIVDHYKLGESSTADEDDEEAVQNILVYINDVAFSLPAVELAANFPQKSYFLAFNEKNPWEGLFKGEASHILDVAFLFQNFNDQLSPEQRKAAEQFGKDVISFVSGDEIWPAFNKTQHTMAVYEDGKSKIIEPPSEEEAGRNPFVFTVTTGTDAPSKDLLYKTFVDFMAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHN8</accession>
    <name>A0ABR3YHN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Catechol dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010262</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000124">
        <property type="protein sequence ID" value="KAL1887382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="128"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="37869" checksum="AD68FBF9F10ED2E1" modified="2025-10-08" version="1">MENHTPPDRALMKDLTIENITDNVCIINSNCDNVRLKFLLDRLVNYLHDFARETRLSITEWEAAIGFLVQVGKISTDVRHEFVLLSDVLGLSLLVDAIDHPKHPGATEGTVLGPFHTADAHVVGAGHQISHDPNGEPLLAVCSIRDTAGRPLGGVSVDVWETDSKGFYDVQYADRVEPDGRAIVESDADGVIFFKAIVPVPYPIPHDGPVGKLLMKLKRHPYRPSHMHFMFKKPGYDRLITALYLRGDPYESSDAVFGVKESLVVDLYKVGDHEGYAEKYGVPPETKLLTYDFVLLTNEEALKVRDAEAWKEAKRQGGLKVVDGLLVPEDASETSTTKTATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI45</accession>
    <name>A0ABR3YI45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000117">
        <property type="protein sequence ID" value="KAL1887512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168807" description="GPI anchored serine-rich protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="21520" checksum="FE6DD0E83B2EDD88" modified="2025-10-08" version="1">MKSALVSLLALAAYATANESFGLPGGDEDCSDEPSYASSTGILVPSTTIHSNPTTPAAELSPPGVELTTSTIFSTTTSTIISCHPTVVSCPAESTVLTTVIVAVSTTVCPVTAGATTTPVAAVSPPANTWVAPTSAPATSAPAPPAPAASAPSSAVVVPAPAASSAPASKAWSSAAHPSGVAAGTGTSAPKTPTTSSPHVVVTAGAAHNGLGAAGAVAAAVAVAALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI76</accession>
    <name>A0ABR3YI76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytosolic Fe-S cluster assembly factor nbp35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">NBP35</name>
        <name evidence="10" type="ORF">Sste5346_010130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="86"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="37115" checksum="20900FF974F9747F" modified="2025-10-08" version="1">MAPALELPEPVEDVLSNPLKSKPKLVAPEPEHCPGPESEQAGQADSCAGCPNQEICASAPKGPDPDIPVITTRLENVKHKILVLSGKGGVGKSTFTTLLAHAFSANPDSNVGIMDTDICGPSIPKMMGVEEETIHVSSAGWSPVWVTDNLGVMSIQFMLPNRDDAIIWRGAKKSGLIKQFLKDVDWGDLDFLLVDTPPGTSDEHLSVNAFLGESGIDGAVVVTTPQEVALLDVRKEIDFCRKAGIKVLGIVENMSGFVCPKCRHESQIFRATTGGGRGLAEELGLPFLGAVPLDPRIGMACDYGESFFDSYPDSPACAALKTVVRTLAGELGLDGSQVLPEDEEEKAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK21</accession>
    <name>A0ABR3YK21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 69 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 69 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="62310" checksum="E159464B9FA8DBD3" modified="2025-10-08" version="1">MRSTSPDERAAFLASANGGIGSPPPFSLDDDPDPNDTFSNNDNDGQSQGLLSKEGQSPRRTSRLWRCCACFGLCGGRLSRRGPKWRFFGLVVKTFLGIVLALLVLTPLLAPSYLHPPKHYTQLADKCEALYNGPEESLDRIHGCANPREEKVFISVSLYDKDGHLAAGEWGQALVELVRLLGPGNTYVSIYENDSGRRGASALERLRRQLPCHNTVVYDEHVPLDIFPNVILPDGTTGTKRLAYLSEMRNRALRPLDTLAGTEGYIFHKVLFLNDVAFRPLDAAHLLFNTNRDSEGRAQYLAACALDYKTPFLFYDLYAQRDAEGFSNGLPIFPIFSRAGKGLSRADMLAQKDAVRVQSCWGGMVAMQAKYLQHWNDTLARPDFHVPGSNVIDPVHPTGISTPVRFRYEPELFYDACECCLLFADVTKAARKAGRLAHEMGVFVNPYVRVAYDWTTLSRLRLVQRWERLFSLPQAIISYFASLPTNNPHRLVKEGDKFVEEVWSSKANSWTLEARTGRNGMFCGVREMQLLDPSPRQGDKNWANVAIPKGQALDFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK24</accession>
    <name>A0ABR3YK24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nuclear transport factor 2</fullName>
            <shortName evidence="1">NTF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NTF2</name>
        <name evidence="3" type="ORF">Sste5346_009538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000091">
        <property type="protein sequence ID" value="KAL1888494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="123" mass="13918" checksum="71EDE3F22F073E96" modified="2025-10-08" version="1">MASNFQAVAEQFVPFYYNTFDADRSQLQALYRDNSMLTFESASVLGAAAIVEKLKNLPFQRVKHVTSTIDPQPTIADGVIVLVTGQLQVDEEERPMNFTQVFHLAKDGDNYFVYNDVFKLIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL83</accession>
    <name>A0ABR3YL83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional AP-4-A phosphorylase/ADP sulfurylase</fullName>
            <ecNumber evidence="4">2.7.7.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">APA2</name>
        <name evidence="4" type="ORF">Sste5346_009469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.53" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF3">
        <property type="entry name" value="5',5'''-P-1,P-4-TETRAPHOSPHATE PHOSPHORYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="2">
        <location>
            <begin position="199"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="362" mass="38219" checksum="7A3163EA845D7D26" modified="2025-10-08" version="1">MPPIPANLPDLVRAAFVRAKASGDLTFFPTQVALLRVQGVPFQLRFAPALAKKPKGDKKDDSGKKDDKAPPPKPYDPFEEPPSGLVVLPELNGGSHRLVLNKFAVSQDHAILATTAWRPQSHLLEASDMEAAYVCIQAYADCSEELYVFYNSGKYSGASQPHRHLQLLPVSQMREGLKGDSEGEWSVLADRLLGSDSHEVPFYVAAARLRGDDGTGDAPSAERLHAIYLDLYRQARAAAQGTSAAIEAADGYNTVAEERGELPASISYNLALTHHTMALLPRTAEGGTDNQYSLSLNGTVLAGTALVKNEAEWDALRSDPTQLGGVLAQIGVSPGSAGTTGAAGNGGAAAAGLRGRPSPSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLJ6</accession>
    <name>A0ABR3YLJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009651</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF58">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="593"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="831"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="916" mass="100037" checksum="9867E0DB9FEDBA39" modified="2025-10-08" version="1">MAPLTFSHLSSDTFEQESQKKAGRKRPRIREAVSCWQCRSRKIRCDREVPCRPCVERGAGSRCAYNKNKTTSSTTTSTSKPTSPRAQDVTTSNAPKQTVDGEPATDKASPRSTTSTSSRPIVAAPKSTTASSPTALPTRTQHNTRSLPPRPAPVSNQPFQGHIIQRSNRKTRFIGVSHWMAPCNEMMVINAMVNRTHGFKESMEEFSELKERLRLANNITPILPPYPLVPGGLSASVLLSVLPDRPSCEQWIGRYFQSYGRIYDIVDATTLASDLNQAFSCPTDERRSYATALDSVYILRILMTVALGMQMSDQHRIHGRRIGCLVRDFVHSAARVQKPCTGSLQVLLLLILLGIIMGSDIEGEYDNMGLLGLTSNIILRMGLHRDPEIFPGASPYFMEQRKRLWACFLRLNLASCIRTGAQLNLRLEDSDCPLPTPNILPVPLTTEALDESTRKCVKEWTLDDKSAQNDASFNYACAKLANVVARVHQVLCSAKPRVTIEQQKELQDGFAALVEELPPSLQSGTAVSDPIVELQRALISVGMHSFLLVVFMSFILRNTTAELAASGDFATQRPQLLEIWDLTTSILSQFQSLSQKESEPKTNKTRSKPKSQLPLPEYPNMTASDTSAMAHHLMWTDAGRAALSGCLVVGRLRRHDIDKTMPFSVHPRQQHTASIFQHMLTQSLSALLDLWRSKSHLGPVTAKISMVIAVAIAVTNSLYIDFDGIFDKGVEAAKQQIAEINFALEKQHAAQPTTSSRTRDSAISMEDAAAATATVNQFLATTQAHQLPIATAGLHIMPTSTVPVPFTSPGTLPSQMVPLTSPQAWVPMPLAGGGPPQLSDLSAAGSSAGSQTTTPDFVGMGGNAPGSGNEMFGLDFGSDMSFPYAISSSFDTGCALMGDFDSAFLDFSNDTVMNMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM43</accession>
    <name>A0ABR3YM43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-ketoacyl-CoA thiolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_009265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="30"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="293"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="44066" checksum="2D66D6C5489A3FD3" modified="2025-10-08" version="1">MAERLGSILKHLAPGKGAVDTITSKNADDIVITLAVRTPLTKGKKGGFKDSTLEYIVYALLQQVRERSNLDPALVEDICLGNVSDAKAAYKLRAAALAAGFPNTAGASSLNRFCSSGLKVTADIANSISAGNIEIGIAIGAESMTVGGDSLEKPFDEEVTKHSQESVDCQMPMGWTSENVASDFGITRAEMDRYAVESFRRAEQAQADGHFDDEIVPIKARVKDAEGNWKEVTLTRDEGIRPGTTFEALSKIRAAFPQWGTTTTGGNASQVTDGAAAVLLMKRSTAQRLGQPIVAKYVGSTVAGLAPRIMGIGPSLAIPKLLAQYNLTLADIDVIEVNEAFASMAVYCRDKLSLDWSKMNPRGGAIALGHPLGATGARQIVTGLSELRRTKKKILLTSMCIGTGMGMAGLFVNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMB2</accession>
    <name>A0ABR3YMB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Short chain dehydrogenase/reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF7">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE (AFU_ORTHOLOGUE AFUA_2G00830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="33176" checksum="9165C287502074FF" modified="2025-10-08" version="1">MSVFQPGNTAVITGGASGIGLALAAKCLASGMHVLVADKDAASLAATPKHASKLAGKLYGSDGTSGSVTTHTLDVTNLEDWAGLRSAVEDSNGPLKGRINLLVLNAGVGGKTPWTDVAAFHKILDVNLWGVIHGIATLLPVVQSTAATANDAPTATTTSIVITGSKQGITNPPGTSPAYNASKAAVRALAEQLAYDLSKEDKANQPKTGVHLLVPGWTFTGLSGNDPIKQHGEDLDQRPKKPEGAWWPEQVVDYLLEAMKANKFYVICPDNDVTEDMDKKRILWSAGDITEGREPLSRWRPDYKDAVDAWMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI1</accession>
    <name>A0ABR3YMI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-mannosidase</fullName>
            <ecNumber evidence="5">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Lysosomal beta A mannosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Sste5346_009020</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="17">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="14">
        <location>
            <begin position="91"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="15">
        <location>
            <begin position="280"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="16">
        <location>
            <begin position="843"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="697"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="708"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="737"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1889265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="908" mass="103286" checksum="573D3FF2DAE0A4CD" modified="2025-10-08" version="1">MFVQYTVDVTHRLHTNPEEDNVLLIMFESARLAGLDRVYGGTKHEYHVHQTEIGRAAIRKAQYQWGWDWGPILNTAGPWKPIVLDSYDCCIGNVRIWTHLSEDHKDGKVTANVTVVGNIRRVRLYAELVLPFGDTDSRMVLEVSVDLSRNKSGHNLSFHVANPELWWPRGYGSQALYTLHLTLLQDEYGGDQHQEQVILDKRESTFGFRQSKLVQQPNSYGTSFYFQINGVDIFCGGSNWIPADSFLRKFNYERLLDLLVESNQVMVRVWGGGIYEYDEFYDMCDKRGILVWQDFAFACASYPANDPKFLQSVEKEARQNIGRLQRHPSLVMWAGNNEDYQIKEHYDLGYDSTSRNPQSWLESKFPARYIYEELLPNLVSEYYGAREGYQAVPYQPGSPYGDPRSTTLKVDPSIGDVHQWNVWHGTMEHYQKYATMGGRFVSEFGMQAYPHHDTLRRNISGEDSSDRRSQLWPGSLTMDARNKAIGHHFRMLKYVADNFRIRELDNPVTFGHLTQIAQADAVSCAYKSWRRLWEGRLCGGALIWQLNDCWPTISWSVIDYYGVPKPAFYAIKRAMAPLAVSVQRKFIDWTTRKAGNGWQRDTGHVELNLSLDVEYQVWVASSLQHIEFCSVAVRFVSIETGLDIIPIVKAGHDISPNTTSTIFVDKALLPEERHGEQPAKEKTATQEQVVEVREKEYHVKDHDALRESQQSSPASAMSPASRSRAFGSPRHSPITIRDSRDLQDDNSHRAENRSSSVAGDEPESSVPNGKNADTKDGLRPTDIGWSTQVLRNSSPCVIHVALYGKYGDLVSTDTSWPDPIKYLEFPNRQIVLNVENLLPDKLSGKVSVTAGKPVKGFVFVEKVGGIRFSDNGFDVIPGEANIVSVERQTVGGPWPELEYTYVGRDIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMS6</accession>
    <name>A0ABR3YMS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol-specific monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="56157" checksum="155D5D88574F86B5" modified="2025-10-08" version="1">MPPTIKSVAIIGAGASGAASASALTAEGYFDVIKVFERREEPGGTWIYDAIPPDLKLVPGGLPHDIDPPLAIPEVLPATTAPNTQERFIKTPIYDGLTTNVPEIAMSLSDRRFPYGPFVPHWIPKNYIREYFSLHGDDSLLFLNTTVEDISPIHEKSRGAQNRWRLTLRKHDRTRGVDEWWQEEFDAVIIGNGHYSVPFVPTVTGLPEFLVNYPGRVIHSKSYRSPKLYAGKRVLVIGNSASGHDVADQLVKYEGVHHPVYQSRHSRSLWEGDEPPEGLVWKPVIDEYKADGTIVFVDGTELGPNDIDAIIYCTGYKPSYPFWNVQQNGRRLYNYEEGRFEGTFQHTFVHDFPTLGLVGLPRTLTFRSFEYQAIALARLWSGRAVLPPLAEQRLWEEQRIAERRYSGKKFHDIEWDTGETDAYLNFHYRLAGLPQLDGTGLTPPILNATTRWAIENIKKYPILRPSPPPHQDANRRAAEDDWVVVETVKDSLWYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN05</accession>
    <name>A0ABR3YN05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008721</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="58"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="56145" checksum="7988CB13BFB5048F" modified="2025-10-08" version="1">MKSDIPIQMVEDAQPSTDNTISNAELADEAQAGKVEVAPPEHDPAVVRRFLWKCDIRLIPCLGIMYLLNSLDRANLGNAKTDGLEKDLGLVGNQYNQILTYYYIPYVLCGPGMAIITRLITAKYSLTGMMVFFGSFSIATAFAKNFGQLLAFRLFIGVFESGFLASVVIYMSGFWTRADIASRIGLFFASNVIASAFGGLLAYGTFQINATRLHGWSYLFIIEGSLTVFFAIVMCLYIPRRLTSAHFLTAEEKAAGVARQLSDSVDEVDGKFSWSQALIELKSWHTYVRILICFSISVPLASNNNFLAPMVARLGYGTAKTNLYTVAPALTAAVFLVAWCFSSDRFRERGLHLCAALLVTTIGYVVLITIDVDNLAASYVALFLTTVGAYPVSPLFSSWCVSNLPNMNSRAFTIGLLIPMGNLSGFLVSNIFINAEAPRYITALRVNLAFAVLAIVLCFSYGMWMRYENRRRDRISGRITTLDNHGHGQEYITDGVLTAKDPRFRFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN26</accession>
    <name>A0ABR3YN26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="35"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="456"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="60815" checksum="C011BCD6A93D425F" modified="2025-10-08" version="1">MPPQQVYASPYAVADIPRNQSFWQFILSHNIDDTLPDKVILQEHERPERQLTYGSAPQLAGLGADALRDVLGLSRGDTILIVGKNSLDYLQVEFSALWAGITAAFGSPTATVSDLVHFIDIVEPAVVFCDAGDVMTRVTAAIGQSKWSKTRRPNLVGIGERGTAKLAFPSDFILDTTKPYSPPIDLTNEDGHTVPSVICFSSGTSGLPKGAVLSHRNLIAYLLVGRSTDPSIASADQRDVFYAPLGHIYGVFTASLPLLTGGYVRLLRDYTLREYVKACVQVRATTLRMVPPTLVAMVKDPFVRQQDLTSVRTISCSGAVLAPDIISEVHKVLGTEAHIVQGYGMTEGSATSLRSFSAKRKQGSVGKPMAGMKMRFVDDDLNDVPEGTTGEIMFSAPTVFIGYKKNQTANAEVFPFNDGWLRTGDVGRIDSEGYVWLTDRKKDLIKYKGNQVTPAELENVLHSHPLVTEAGVCGTWDSVQETEVPVGYVNFKPTVPVADRPKVLREVLEFVNSKVAKTKKLRGGLFYLETFPRNPTGKLMRRSLPARLQAAREAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN93</accession>
    <name>A0ABR3YN93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="334" mass="36478" checksum="411FFA630AE81FD3" modified="2025-10-08" version="1">MGSPVVIVLPVRPAALLSHILEHCTYPTTLVICSTSTDFVQRCANDAGQHGDTDGSVLHTASLLQVAVARHIRVAFVPTVAHLRGFLAALDLKASRVPAPPTAEVLLLSGGAPPPARRGDHTLVVYDFLRLHRDTSEWSSQGLSASAAVLVEAGWRTRLEVLVVDGAGGQPGETATTTTALDEKMPVLSTGPRRQLQRAGYPLRSERIRAVLSRWFSFRDTLEAPKEERPAVESMVEEEQPRSERDATVGPVEVKELKETDETEKTEKVEEAREVPVAATENEDEAGTIDVDDVPQASPRVDETIRVPEEKPRRTFVKDSEDEDDDLSDDGLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNE6</accession>
    <name>A0ABR3YNE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF18">
        <property type="entry name" value="NICOTINIC ACID TRANSPORTER TNA1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="66"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="518" mass="58168" checksum="8DE097C953D1163E" modified="2025-10-08" version="1">MTDTAEKTAGTNTDLAVHAETNTVSVIYDRDEDGDTKPAAGLDESNLPNYDDAETKRVLRKVDYRLVPMLMILYLICFVDKGNIGNAKVAGMNKDLGLTDAQYNLALMIFFIPYTLFEIPSNIVLKLIRPSWWLAILLISWGTVMTLHGIVQNSGGLIAVRFMLGLAEAGFFPAAAYLLGEWYCRFELQRRMSMLFVSASLSGAFSGLLGFALELMDGVGGLKGWRWIFIIEGIFTAVVGVILPWALPDNPETASFLTPAEKLFIQQRLQQDSGTSSGHLQTNEKFQWKYIRDTLKDWRIWFTIFIFWGNTVTVYSFTFTAPTIILELGYTAAKAQLLTIPIYVTGAIFSVVIAWFADRRRTRWPFIVIPYTFSLVGFVGIMATPKERYPGVVYFWLFFIPGGVYAAVATLVSWVSNNLSPTWKRAVGVATSIMIGNMGGIVGTNIYIAKEAPNYWTGYGISLAFLVNAIACTFILRHSWSRENERRDAISEEEVFATYTEQELLELGDRSPLYRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNI6</accession>
    <name>A0ABR3YNI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">D-xylulose reductase</fullName>
            <ecNumber evidence="8">1.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Xylitol dehydrogenase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_008844</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="11">
        <location>
            <begin position="19"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="37235" checksum="A79C521A8FD99DCA" modified="2025-10-08" version="1">MEPANLPSANYVCIMQAKGKLGWESRALLTEPGPYEVVVAPQKTGICGSDMHVFLSESAGKDASKKPIVLGHESAGFVTNVGSQVTTLKVGDRVAMEPGKYCLRCEFCKGGSSDVCYKLPDGISLEEGALIEPLAVAIMVVSSVAQMPHNANVTVFGAGPVGLLTMAVAKALGARRILAIDVQEQRLAFAKEYAATDIHSSLPKEAGEDSITYAQRHAQAISDKFGLDAPGRGMDLVMDCSGAEVCIQTGIFLTKRRGTYVQVGAGMPNVLVPMVTVLVKEIRIKGSLRYGPGCYDMAIDLVHQGRVQLKQLITHRFPFNQADLAFKTTKDGVGPDGRVAIKTIIDGPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP01</accession>
    <name>A0ABR3YP01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative glutathione-dependent formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="5">4.4.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">S-(hydroxymethyl)glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008546</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-(hydroxymethyl)glutathione = glutathione + formaldehyde</text>
            <dbReference type="Rhea" id="RHEA:22488"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="4.4.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.22" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00723">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014185">
        <property type="entry name" value="Formald_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02820">
        <property type="entry name" value="formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003829">
        <property type="entry name" value="PRK05417.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033318">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="20"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="190" mass="20046" checksum="AA6C8D64E22951E9" modified="2025-10-08" version="1">MSPSLHPLIDNGLTKGDANLAGGVLRCQCSSSPVEVTLTSNVLHNHACGCSKCWKPSGALFSVVGVVPRDALSVTANEAKLTIVDPAATIQRYACKDCGVHLYGRIEKAHPFHGLDFVHAELASTPGNWQEPQFAAFVSSIIEQGFDPSGMDGVRSKLKSVGLETYDSLSPPLMDAIATWTAKQSGALPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP34</accession>
    <name>A0ABR3YP34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acetyl-CoA hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetyl-CoA deacylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ACH1</name>
        <name evidence="8" type="ORF">Sste5346_008733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O = acetate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="3.1.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.70">
        <property type="entry name" value="4-hydroxybutyrate coenzyme like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="entry name" value="Acetyl-CoA hydrolase/transferase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046433">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43609">
        <property type="entry name" value="ACETYL-COA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43609:SF1">
        <property type="entry name" value="ACETYL-COA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-CoA hydrolase/transferase N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Acetyl-CoA hydrolase/transferase C-terminal" evidence="7">
        <location>
            <begin position="332"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="525" mass="58313" checksum="A958786845A2084C" modified="2025-10-08" version="1">MASAALKSRIQRASMLKKVCQPQDLLHHFPNGTYIGWSGFTGVGYPKKIPTFLADHVENNNLQGQMRYSLFVGASSGAETENRWAGLDMIERRSPHQVGKSIAKGINNGSIKFFDKHLSMFPVDLAYGYYTKDRPNGKRNLDVTVVEATDILADGSIVPGASVGATPELMQMADKIIIEVNTALPSFEGLHDITTTDLPPRRKPYLITTVEDRIGTTSIPLDPEKVVGIVESDYQDQTLPNTPADESSFQIAGHLIEFFEHEVNQGRLPPSLLPIQSGIGNIANAVIGGLQNAKFWHLKVWTEVIQDTFLDLFDSGHLDFATATSIRFSPDGFKRFYSNWESYKDRLLLRSQQVSNSPELIRRLGVIGMNTPVEVDLYAHANSTCVNGSRMLNGLGGSADFLRNAKYSIMHTPSSRPSKTDPNGISCIVPMCTHVDQTEHDLDVVVTEQGLADVRGLSPRERARVIVKKCAHPLYQPILSDYLDKADSYCLKRGMGHEPHLLYQAFDLHRTLDEQGSMLKFNGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPF9</accession>
    <name>A0ABR3YPF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Snf2 family helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_008687</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056026">
        <property type="entry name" value="DUF7607"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24580">
        <property type="entry name" value="DUF7607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="991"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1346"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="107"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="584"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="827"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="908"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1662"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2065"/>
            <end position="2258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2272"/>
            <end position="2395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="910"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1662"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1705"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1721"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1740"/>
            <end position="1750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1758"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2071"/>
            <end position="2080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="2160"/>
            <end position="2169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2187"/>
            <end position="2200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2219"/>
            <end position="2240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2249"/>
            <end position="2258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2272"/>
            <end position="2282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2323"/>
            <end position="2335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2340"/>
            <end position="2362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2395" mass="265152" checksum="468F0FC1A92CABA6" modified="2025-10-08" version="1">MSGSGGNNNDPFEWSNERLIQELCTTKRSWAAPPPKRWPDPALLSAKLEEHDLDGETILCYEDYMGQGGFESLCADLGITKIPHKLSLRVAIKTFQKMSPGYRAWKTSQAASDNNEPVTIPSPSPTKTLTSTTERTPAAAPAVQNGEGHAALTAPKPAPKPAPKPAPEPAPAVVVGTSNSTSNGIANGTADAKNGHSYPDAMQIDTPQPPPTSPLDRSKKRKRVMPTNVSSTTRPRKARSNGPFGDLATVTMDTGSNGLWKKSKRGAYLGDWSLTRYTLLQGADPLDPNNTDDEDDGDSDFGWSAPRPIPSGRRLQVHRTLQHYFQPSKISIPHLGRTRTAQASDPLGLGANPAEDDEVLPALGESDDEGYDTETWEAMELEAKEREREKNNNGEPKKKGQFLPIETVDTVLVEAIRDIEKKWAEKKMDKRRRSEHKLWNKARRDGSRKLLMSRAREESDKLGQRIDKLVQEIRQVAWKNEKEIRLQSAVLELSIEERQDARWRARLYSSPTAPTKVVVARTAPRRRLSSKAARLKALENDEEILTSSSSEGDYDDDPRMHNFIINDEIVGALASGGGLMDLDGDGNGTLSDGPMSMSDGNGADDKDDNEGGRATRSSSMNSEEQEIIRRLDAQYESRIFGITKAPLEICRQDREPGPPPRPLADFHKLDGVQGLLGLLDVDFSLEDMPAIVDKGVSYWEAAGDVTRLLCTIFWTADREQLSRLVDYCSATTDVDVVWRNFCVPVLENEGDTSVPRTGPEDDTTAFTRYFYIFVSCRDLPFRNFDPKGEVMKVFIEHKQGQLGKFCVKLRTLAPYFIEIKTKSITPLPDTAPTAASTSTSTAVPGPSTAVRTGIEVVDIESDEDDEDEDDELDIYDVRPVARRNVFDDDSDSDDDVIFSHSLNRRRHIRKDQGAQDLRDQDKARHQEQENRRKALYESLAQSGTLSQDQTRLIINTAKDAHHGIVYVNDWIGRNIRDHQIEGVRFMWNQIIAPPESRQGCLLAHTMGLGKTMQVITLLVAIAEAAKSPDESISSQIPDDLKQSKTLILCPSGLVENWLDELLAWAQRDTLGRAYSVTSSMHNIARMDTIRQWAIEGGTMVIGYPMFLQVLKEFGEEASNLLEQTPNIVIADEAHTLKNSKSRIHQVTRDFRTSARIAMTGSPLANSVDEYHSMINWVAPNYLAARDEFRATYSNPIREGFYRDSTKPQRRHAVKMLKVLKDTVAPKIHRATIASLQGVLPEKREFILFLPLTPLQMRVYKIFVEGVNAASFMPGISSTVQLWNTMVNLTLLLAHPKIFKMRLEEMKKHKPTTARSGTLPKEMIDALSVAVESPNIDSPMHSAKIMVLIGILDEAKRAGEKVLVFSQSMLVLDHLQGMFRRQKRRFQRLDGDTMVNKRQAQVKDFNVGTDEVYLISTTAGGVGLNIQGANRVVILDFKWNPINEQQAIGRAYRIGQTRRVFVYWLIMDGTFETVLHDQAVFKTQLASRVVDKKNPQAWADQVRNYTKDPEIPRIMYETIAKQEGKDVVLDALVRPGAPTNGRICRVISTDTFEQEEPEESLTNEELLETANLVNMNRMRLRSGTVLGSAVAAGFEAGFQVVGAPGMPPPAEAATIPRLERTQVDGASFPPTTLAASRAIAHVAATRHTEPQASATPPYLVLASQSQQPAQTPAPAQNQNPIPSMYAHDSFITQPPGLPMQISSQNAPKLSKPPQLPAQLPAQPAPPKRPSPRLPPPPPTMTVPSNGHSTVDNDWFFDPVPEPAAAPAPAPAPLSMARPLSTPAPVSMPRTIPTSAPALESEAAQGLRPERFLQLPPLPLAGSSDDFINSLTDKLLNGSIPQQQCIYKLQTADLLARRTVEDMTTFFVSSGLPAKAHWGRLNHLARSSPEFVEAAVFGMINPQLLATFNAMEERQMTDCINAAMAEIDTRPSEYNYDTTPNTCTLLANQKTVIRILERKLFERSWTRPDKAMRNLMVAKKLAATAVLIHIQEHQIPLLTRCAVRAFRDPVFANAFAMPDFDYDGWAAITLAQEDHFVRRLHFRHMTEYPQEYQNGYLKVLYSPGDNSPLPPRTTLNSKNTVARTAKPEPMDDTALNDIPSRPHSLAGTGTGGRASFDESFSTAAAATPPSRPLGRVVHAHGQGETRSEAGGTPVRAKDPDHVKHHLKRSQSRNHETLDRGPMSLGRSDGAGPAPREGGARPRMSSDLIAMREVMERRQRKTAAQSSTPPPQASQASQAQQAPPQEPHRRSPNNPSLNLPNMPAEWQRAARGNTTYTSKSGNAMSQAAASQLPMPPQPQPEQQPVNAFVPETQNFHRGHPRIDPASQLQRGQHGQQTPHKSRSQLERELLEADRRQQSAKKDKNDGNGNNKPKILPPPPGRTSGPQAGDNARNPFVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPX1</accession>
    <name>A0ABR3YPX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HPP transmembrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="3">
        <location>
            <begin position="57"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="334" mass="36556" checksum="509C3C12B6EF630A" modified="2025-10-08" version="1">MAKRPSFLTAAAWQFNIDAHLNRFLAPSVVPHLPRPVAHFLGYRPPPPARQQRKIGNLIIIAWAFIGVFCGVSVVNVVSYHIPDFIGVDGAVTTVGSFGAAAVLEFYAIESPLAQPRNAVFGQLLSCIIGVAVTRLFSFLPPDRFEDLRWLAASVACAAATAVMALTGTVHPPAGATAVIAVTDDNAYQLGWKLIPVVLLGSVLMQVIALIINNLQRRYPMYWWSPEEVGQFWTKSDASEARNKTADEKEPADADKESGVAIPDEEDPDPEMGHVTFTRTRTPSTSVPLTAVASLENAIRHPRVTITRNRVVVPDSIYLRPEERLMLEALSERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ04</accession>
    <name>A0ABR3YQ04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046031847" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8351" checksum="249DC5ADF295E135" modified="2025-10-08" version="1">MKSVSFVSLLSLLSAPAVVLGQNFAAIALGAFNDGGIDNYWVQAYCYDCNGDTTPFLSELDLGDCLLNNNGQLVRFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ28</accession>
    <name>A0ABR3YQ28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="7">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008474</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047090364" description="(4-O-methyl)-D-glucuronate--lignin esterase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="4-O-methyl-glucuronoyl methylesterase-like" evidence="9">
        <location>
            <begin position="101"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="394" mass="41084" checksum="31DAB5E7B0CC8A7D" modified="2025-10-08" version="1">MLRKTLLLAAAAGAAHALPLAATVCPAQAGDYAAVDNAQLPDPWTFANGKPVVTTDDWACRQQEMSQLLQQFELGALPPAPDSVTATISGGSMSLSIKVGSNTKTVSVSLSKGSSGAAIIAVGGSSIPIPSSVGKINFGNDACAAQANPASHGTGWFFDLHGKTHPAGALTAWAWCVGRIIDGLEQLGADKTGIDPKKLGVTGCSRNGKGAFLVGTLEPRIALTLPQESGSGGAASWRVSDSEKTKGKSIQTAHQIIRENAWFSHNFDPYVNKTNELPEDHHFLPALIAPRGLFVMENDIDWLGPVSTTVAMKAGRMIYDALGVRSNMGFALVGGHSHCSFPSSSTSDLNSYINKFLLGTGKTSDAEISPANVTMSDWISKWSATPKLAPAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQC5</accession>
    <name>A0ABR3YQC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_008518</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF20">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="41"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="570" mass="62098" checksum="B93F950F3608B710" modified="2025-10-08" version="1">MAGGAGGGSAGFYDAALARRQALMGASGARALLKNFRVFAIAAFACIGGVLYGYNQGMFSGVLAMPSFQQHMGEYDPFDANADQTKKGWLTSILELGAWVGTLLSGFLAETLSRKYGILVACTVFMLGVVIQATAIKAGYQAILAGRFITGMGVGSLAMIIPIYNSEVAPPEVRGALVALQQLAICFGIMISFWIDYGTNYIGGTTLGKQSEAAWLVPICLQLAPALILFLGMLFMPFSPRWLVHHNREDEARKVLSHLRGLPADHELVELEFLEIKAQSQFEKRTVAEHFPHLRTPTAWNVFKLQFVAVASLFKTRSMLKRVAVATITMFFQQYYAPTIFQQLGLSGTTTSLLATGVVGIVMFIATIPSVLWIDRIGRKPALTIGAIGMATCHIIIAVIVAKDSDKWKNEAAAGWAAVVMVWLFVIHFGYSWGPCAWIIVAEIWPLSTRPYGVSLGASSNWMNNFIVGQVTPDMLNRISYGTYILFGILTYMGAAFIWFFVPETKRLTLEEMDIIFGSEGTSQADFERMDEINREIGLTAMLQNGAAGPVPTKEAAPAAVLEKEEATDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQP1</accession>
    <name>A0ABR3YQP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vesicular-fusion protein SEC18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEC18</name>
        <name evidence="9" type="ORF">Sste5346_008129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="365"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="647"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="860" mass="92440" checksum="C046255333366E44" modified="2025-10-08" version="1">MDLRNNLFGKGPRGGLPGRPGSGGGGGGAPPLDYGHPRGYGGQPPQSPGYQGGGQPQQYGQPQGGGGGGYGAPPPNYGQQQGGGGGGQRPVSTGGRAVRLRLAKVEDKTLQQMYIFTNICAVSPRDFPPSRDGSDLYLRLTGSMIDGDYVVTARPTPGFPDGCISLSDPQRTWLRVGMMDELVAEIYNPFSSSTGRQSYLGSMDVEVGFASAKKFTDTTYDQDALAQQMTQTFANHIFSPGQRLLLDVRNTPLSLVVKTVQLADLSMEKAGAGGAGSEGAVRTDPAARGIMVPQTNIAFYKNAGSPMKLSGSTKRAAANSIIAPDFKFEDMGIGGLDNEFSTIFRRAFASRIFPPGLIEKLGVLHVKGILLYGPPGTGKTLIARQIGKMLNAREPKVINGPEVLNKYVGQSEENIRKLFADAEKEYKEKGDESQLHVIIFDELDAVCKQRGSGAGGGTGVGDSVVNQLLSKLDGVDQLNNILLVGMTNRKDMIDDALLRPGRLEVQIEISLPDETGRVQILKIHTAKMLQNDILDRDVNVDKLAARTKNFSGAELSGLVKSATSFAFNRHIKVDTMAGISDDVSQMKVNMSDFENALTEVKAAFGVSDEELEQALTYGILDYSVNIQSIVKECMVYANNVRQLDRLRNLSVLLHGPAGSGKTALATHVAIQSAFPFIKAITPENLVGYFNEAGKKDYLHKVFTDAYKSPLSLLIIDNIERLIEWNPVGPRMSNVMVQALMTLLKAPPPKGHRLLILATTSRRSVLDQIDMTESFDRQIAVPAVADVRELATALQQFGAFPDPADINQAINTVRQYNGGSDQVGVGIKTVLTMAESAAMVDDSANWFAEQISRSIAANNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR53</accession>
    <name>A0ABR3YR53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF4">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="8"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="33153" checksum="CC094E471F16B6C5" modified="2025-10-08" version="1">MKAVQILGDASSPNIVTTDSIASPGPKGAEILIRVLASGVTGDEVLWPELYETASRIPGHDISGVIAALGPDYNGPLAVGQDVVALLAADRGQGQAEYTIGLADEVALKPDSITHEEAAALPIPVLTAWQAVMDHGKLTAGMRVLVTGASGAVGTLAVQFAMKLADANVIALASSRNHGTLKQLGVQDVHDYNTPGWEANIKDVDVVFDTVGGNVLTKTWETVKSDGIIITVGDPAPAWAFGRSKAPESADHPDVRYMHFIVNADSHTLGRALEMIGDGSIKPIEVESFPVEKAKQAWDRARQRGRSKKIVITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRG0</accession>
    <name>A0ABR3YRG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="451" mass="52272" checksum="D845DEF1E524C0A7" modified="2025-10-08" version="1">MAQWLDQPRKRTLPLVPDAFPNIMVYASLRRLPGSDICDDYESAAETYCRFFPTLNIPQYVSTLTDEDKAWLDKRANRLANRAIDNELSKVSEFCWEVCAWNDVFGRILDDQSLLIDKRQYEYVEVTDKTDETGKVEKTVRVCIPDATMGLRTYNAAELKKGFNCTMPDCRDDHRLKTPDVRLARQRLLDMVRHPDCGLLVDGRWGCADLVFPFAVYEAKKNPEDHDKAEEQVHDACRTYLALLDDLARDPTTNLATYQGYEEEDPSETIRPVKPPKNPRKTDLPLYQMFAFTSSGPHWRVFVAGSLSFFSPCAIEPIWTGDVRDFRSAHKLLCLVDQIHAYAERQHRNFVMQHLHAWYVWYRAQVMDNKVVVDTKMMDDTDDEAGNNGNDCNNSNQISKDHAQDLEKIVGGKEFMKEVRTPEWLSLQHDTKYARQIQAFQTRHKKRKTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRG2</accession>
    <name>A0ABR3YRG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">18S rRNA (Guanine1575-N7)-methyltransferase</fullName>
            <ecNumber evidence="12">2.1.1.309</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BUD23</name>
        <name evidence="12" type="ORF">Sste5346_008185</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.309" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="10">
        <location>
            <begin position="126"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="11">
        <location>
            <begin position="268"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="70"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="35353" checksum="960EA5ED1AF93A6C" modified="2025-10-08" version="1">MSRPEDTLAADIHYDDTEARKYTTSSRIQNVQASMTRRALELLDLPGPSFILDVGCGSGLSGEILTRSGTSIRRKRSGSDGEAGGDDDDDEEGGDDGDDNDSSSEYSGLSDSDSIEEEIGNGPHVWVGMDVSPSMLDVALQRDVEGDLLLADMGQGVPFRAGSFDAAISISAVQWLCNAESSDTSPQGRLSRFFNGLYASLRRGGRAVCQFYPKNDTQRAMITQAAVRAGFGAGILEDDPGTKNMKVYLVLTVGSGQTSGDITGVVSNMDGVDILDDRGARGQNGRTKNKNIKKGSKAWIAKKKEQMERKGKIVKASSKYTGRKRRIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM2</accession>
    <name>A0ABR3YRM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="149" mass="16091" checksum="54C35B4265E26333" modified="2025-10-08" version="1">MGGGGDGIDDGTTEDGEATIDKEDDGAGEDNDGSGEEEDDGTGDDDDEICEEDEGLIEDDEGGREDKVEDEEITSKEDDEEMADEDGEDDGKDDGEKTDEDDDDGTTNRELLELLGLQAEAEALPARSIVVRRQAECSFMVNYLNEINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRQ9</accession>
    <name>A0ABR3YRQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-3-phosphoglycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04902">
        <property type="entry name" value="ACT_3PGDH-xct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12173">
        <property type="entry name" value="PGDH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF22">
        <property type="entry name" value="D-3-PHOSPHOGLYCERATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="Serine metabolism enzymes domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="7">
        <location>
            <begin position="37"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="8">
        <location>
            <begin position="138"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="D-3-phosphoglycerate dehydrogenase ASB" evidence="9">
        <location>
            <begin position="377"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF19304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="67138" checksum="D498E34A58C5566C" modified="2025-10-08" version="1">MAPSAVEEPVTAVSAVPAAVSTSAPAASLATDNRPRILVPEKISPDGLAMLQDLYQVDIRLGLSAEELLQTIPSYHGLIVRSETKVTAAVLAAGRKLRVVARAGVGVDNIDVDAATTHGIIVVNSPAGNIRAAAEHTVALLLATARNIGRADTTMKEGKWARSSLVGVEVGGKVLGIVGLGKVGMQVARMAKGLGMRVVAYDPYASPEVARSAGVELVANTAGAPGSETTGLDALLPQVDFLTIHTPLLATTLNLLGETQFKAMKPTARVLNVARGGVYNEEALVAALDNGWITGAGIDVFTDEPVKPDPEGNNHSWAARLAAHPKVVATPHLGASTVEAQENVSLDVCAQMRTILRGGLPTAAVNAPLILPEEYRKLQPYVRLVERMGSLYTQHFNRASRTGGNNRRPRHRFELVYRGELAEVANTRPLFAALVKGLVSSVTDAGGRDVNIVNATLIAKEKGLAIRETHDRGEGGSGVSLRAQADDEVSTVVTPEEDGPQLAPVADTAAEVSATPATAVLPDEIIEGYVSGKSIYISRVDRFVANFVPEGTLLVLHNYDEPGKIGHVGMALGRHGINITFMHVASVDRGGAARRRSVTTGTENEALMILGVDGPAVTPAVIDDLRESEGILDVSLVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS09</accession>
    <name>A0ABR3YS09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_008054</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF3">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="815" mass="91013" checksum="92A9DCA51C8962CB" modified="2025-10-08" version="1">MSDGQGQSSTATPSISTPSASTSSSSSSPFACTVCRKTYKRREHLQRHVLSHAPVPPHRCSICGNCYRRPDVLKRHFATCQARASGGSLSSLKRRACDRCVQSKKGCSTGQPCTNCQAKGVLCEYSFARDGLESSSMDTFWAEDDTSHVEDDTVNDANDSIQNDDSTDGGGHPSTADAAGDGHLGFVVVDNPINDTSTTNIANTTLNADCEMQPVPTMMELNRPSPFAYLDSNATDFILDSNNQVRVQNASWLDFLNLTNEGHQTLTTADDDEQNQLLNSYTFHFLDNFTKKTGLVTFDCGTPLQAKQVVDSLRLMGDANVSAGLLPNTAIVTNVNGDPRLSLDSTYSFPLQPSPFQDPLIVKTHQILFRIREVATVKPRNSTVTLDWSTALEQQCLHFFSPPNLHKFLALYWARWHPNVNIVHRPTFDPVDSKCVLVVAMALIGACMDADDNKQASMWFNCVEEIVFIDDDFCSPPQGDPQNAGLNGGPFDPVTNKRKIQALQASYIVCLYQNWEGTNESKQRIRRYRFSTVVSVARDIGIGSARHVDYGAATFHAFHWKAFVAREQLIRTFLWIYLLDQAFVIFNNLPPRVMIKEMVMHMAWPESTFQATTAADCAREAQLWLRRSAPLHNVTLREVVESFCSGVIVPDICRTFADLGPLNLFCIVSAFHFLIFQKQNSFGGEDQLHAIRTGLANWKNVWEMYKREFSAGPPHTMVPVPPLGEDDTTAPDDMWRRTGFMRNSPEYWLLAHLVIDRLSSQTQARPLHSAIYSHLHSGPQTVDNTAQNPILAKYDETSMRQVNDLISQFRNVQLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSJ0</accession>
    <name>A0ABR3YSJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA thioesterase</fullName>
            <ecNumber evidence="3">3.1.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TES1_2</name>
        <name evidence="3" type="ORF">Sste5346_007781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="1">
        <location>
            <begin position="49"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="2">
        <location>
            <begin position="158"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="357" mass="38738" checksum="BC1F96DE0A45AFAC" modified="2025-10-08" version="1">MTSRNHPISSIESLLHVQPFIEGDPETDVFVDQPDHADNQQALNALTGQGGRLFGGITLGQSLNAAQQTVSPDLVAHSMHCTFVSGRLATVGVQYHIERVKDGRQFCARLVRAVQNRRTFFLALVNFANLTKFSTKTDGLQYGLDFPHDVPTPPAAYDVDVGSKSTIPFLHHSVGIRTSGTDQDSSSSSNTPTRIHQWMRAREPISDHNGLNKDAHLAALACMSDAYLLAGAPHTHGIYDFVSPPVSEVYDGDHRLSLFSKTHQPIPRPHLGFPGAGGGGDLAVTSMASLDHSLYFHDPVRLRADQWLLCEIHSSWAGGGGRALVHMKIWGRDGTLVASCSQEGLVSLGDKPKESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSJ7</accession>
    <name>A0ABR3YSJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Inositol oxygenase</fullName>
            <ecNumber evidence="4 12">1.13.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Myo-inositol oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_008017</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>myo-inositol + O2 = D-glucuronate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23696"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="EC" id="1.13.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the myo-inositol oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.99.1" evidence="4 12"/>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007828">
        <property type="entry name" value="Inositol_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588:SF0">
        <property type="entry name" value="INOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588">
        <property type="entry name" value="MYOINOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05153">
        <property type="entry name" value="MIOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="321" mass="37095" checksum="501678ACBF31C0AA" modified="2025-10-08" version="1">MAPTAIYDDVPVVSATKAKSGRALEEMSDAIDEVNVLKDQSLGTPPPAYNEGSKFDQEKDKTQFRQYDDACDRVKNFYREQHEKQTVAYNLKARARYHSASRKREAMTIWEAIEKLNTLIDESDPDTELSQIQHLLQSAEAIRRDGKPRWMQVTGLIHDLGKLLYFYDAEGQWDVVGDTFPVGCAFDRERIIYPDSFDANPDATHPVYNTEFGIYSEGCGLDNIMLSWGHDEYLYHVVKEQSLLPAESLAMIRYHSFYPWHKEGAYRKLMSPKDHAMLEAVKAFNPYDLYSKSDDVPSVEDLKPYYMELIDEFFPQKVILW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YST3</accession>
    <name>A0ABR3YST3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="202" mass="22255" checksum="1BCAE041967D230A" modified="2025-10-08" version="1">MAQESIDKYEKGKDELRRQQSLVRWRKDNGQWSSVAEPLLSPIAQSRSSSPQTETEKNPAEHRSSKVQASTLPQRERMSNQEQEIEKTSNEHQHAESALAAAIQGKPNKPGSASIPTITITGSATSLPLADAGASKSKQGTGFDGAIAESQWPHPQHEALFSVFPPECETEQLVEQKRPPSRNSHDRYYIVQTPSGGDEDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSZ6</accession>
    <name>A0ABR3YSZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007641</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="24"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="545" mass="58961" checksum="373C2BE056248BA2" modified="2025-10-08" version="1">MGGRGNVFVGKSAFKTVTPRLLFICIVYAFGSVFFGYDSASFSGVQAFSPFLHQFGTYNAKKSAYALTTQNAALLNSLPLLGKLVGSLAVGPSVERYGHRITMFGTCLIQIVGAVVQVTSKKTAQFIVGRLLVYLAVGFVENVVPTYQSEIASGAMRGFFVGSIQLCLTFGSLIAGIVNNALSGRKDNTGWQIATSIQVIPPVLILLGLYWTPHSPRWLVFKDREDEALAVLKSVRRKEDVDLGVCELELAAMREDAQRHYQNQRKKGPWSDLVKGTNLRRTNIAVGLMSLQQLTGVTFSSSYGPTFYKSEGLGKMAFAYAAINNGVSVVTALLGMIVLDMFGRRSATLHGCWTQGVFLALIGALGSKTNPSTSETNGMVASFILYAAILHMSLGPSAYITAAEVGTGPLREKTMAISTAVNVIVSFAVVYTTPYLLADLGAKLAYLWMAFSFAGAVYVWFVMPELKGRTLEEIDQLFEARIPAWRFAEFETTGLTHDVAAIEQGLSPTKLAGDIELVEETNATRTAQKAEEEGAPTTQTQTQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT49</accession>
    <name>A0ABR3YT49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rho-type GTPase activating protein Rga1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rga1</name>
        <name evidence="10" type="ORF">Sste5346_007731</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09391">
        <property type="entry name" value="LIM1_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09392">
        <property type="entry name" value="LIM2_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09393">
        <property type="entry name" value="LIM3_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF10">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="148"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="212"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="522"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="876"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="677"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="754"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1113"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="703"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1131"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1176"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1218"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1230"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1241"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1264"/>
            <end position="1278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1278" mass="142525" checksum="884A6FCCBA39D881" modified="2025-10-08" version="1">MAGYDNSIHDDHIHNPLQPPPSISSGGYQMERNHSDRSNRSQGQPWQNGGNGNGNGGSDGGYGSMASHPHPPGSPALSYREQHRGDRGDRDRSDRSDRGGDRERTHDRDRDRSRELDRGRDRDLEPRRSAERKHSQQGSSRTTSGQVRTCKKCGEQLTGQFVRALDGTFHLDCFRCKDCGQIVASKFFPADDGNGGPQYPLCETDYFRRLGLLCYHCGGALRGSYITALDRKYHVDHFTCSLCPTVFGAQDSYYEHDGHVYCHYHYSSQFAQRCNGCQTAILKQFVEIFRNGQNQHWHPECYMIHKFWNVRLTAPQDVKPVEPLSETDEAASRRHVREDEEKMEEKVYRIWSVLSTFEESSAACISDMLLHVSNGAYVDGVIVAKRFISHVEILFRSADNLDATMTRLDMKGLSYGREAKLLCKKIVAFFSLLSKSQDSSAAKLGVTQELLSLVTSLAHYLKLLIRICLQGALRIEKDRGAPDGLYQFLDDINDLEALKNEPEDSLRQITASMSRLAANDSDQCVTCRKPIEDECAKSGERRWHLACVNCARCNKELGRTLQDAHVNPYDGKIFCSSCEILNNAEKAVSFEHVTKLQQYVFLLRVALARLLDILHSSGALARALQDESYEGGGKDDDMRRNNRLSIISDHDPNREPSSYETTLNDVRRLRSTRLDKHLSSSFRKARTSRVMGGPEDSSARPGSAGGGAAGGSGPGLHVVEDRVDESMADTMLGRQDALTLDDIPHIVAAEQAREQRMGGFGRQDTNDSADGQQGPPGDRNISEGRFAGGAPGPNRAMSPQKLTGRKYFSELSGLEYFIVRHLAVLTMLPMIEAEFSLEELLGFIESRKPATFWNKFGKAFKNDAKKNVKKKGIFGVPLEVIIERDGADSTDGVGPGTLRIPAIVDDIVSTMRKMDLSVEGVFRKNGNIKKLTELCDRIDREGSDNVGLGQQNVVQVAALLKRYLRDLPDPLMTHKLYRLWLAAAKINDETKRRRCLHLTCCLLPKCHRDCLEILFFFLKWAGSFHQVDDESGSKMDIRNIATVIAPNILFVNSKIPALDSDPMFAIDAVTMLITYIEEMCLVPDELVDVLNDPSLFNNNGEITTKEILKRFGDRTITSGPGQPYGKMGEVMNRHDPSTRPLARRVETDPSVWQDERSVRTVQDAPPAGASIPPYSSAPNQSTPTKWNRAQDDGSLQHVSPYPSQHNLHLDSVDDQPLYPHPQSQPPPPIGSQSRSQSQQRGDPRDPRDPGDMPPRQEWRNSGAWGRGNNGSVGVTGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTL4</accession>
    <name>A0ABR3YTL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xylose isomerase-like TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050312">
        <property type="entry name" value="IolE/XylAMocC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110">
        <property type="entry name" value="HYDROXYPYRUVATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110:SF21">
        <property type="entry name" value="XYLOSE ISOMERASE-LIKE TIM BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="1">
        <location>
            <begin position="26"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="342" mass="37670" checksum="59DB2522A7685355" modified="2025-10-08" version="1">MPIQIAIASNALGKSAAGHTVLRKMEAASKQGFQGMEIAIECLEAHATSVFGHLPIRPARFRAAAADIRKKADSLGLHLVALNPFGAYDGLKDAAAINARLGEAELWFDLCAILRVDIFQITSALYPLDPASFSPDVEILAANMRRLGLMAQARGVKIGYEAPAWGFHLDTWQQIDAVVRKVDLPSTVQHCLDTYHIATRVAGDPLNAEQPVHLEGMAALQASLQEMKASLRPENIAYFQLSDATAADPNQPNYPRRDLDAPPFMIQSRNCRCFPGEGVLPVMEVAKTVFDLGYRGWVTMEVFNLDHWDTRSTVPDEWAQRGMASWRKVEEYCGLNAKASRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTM1</accession>
    <name>A0ABR3YTM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sir2 histone deacetylase Hst2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HST2</name>
        <name evidence="10" type="ORF">Sste5346_007478</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="16"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="308"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="450" mass="48483" checksum="D249CBEDA0A29562" modified="2025-10-08" version="1">MGQEVSNQIDDSTPPQTLSDRSIEAVAQLILDGKAKRIVALTGAGISTAAGIPDFRSPGTGLYANLQRLNLPYAEAVFSIDYFRENPRPFYILAKELYPGQFHPTVSHAFLSLLASKGLLRMLFTQNIDCLERAAGVPADRIVEAHGSFATQRCINFECSTPFPDNEMHEHVRDARVPRCKQPGCGALVKPDIVFFGESLPSRFHELGKLPATDADLVLVLGTSLTVYPFAGLPTMAPDHVPRVLFNREVVGDLGTRADDVLALGSCDAGVLQLADALGWREELDDLWRTMVGDAEVERQRGQEALLAAAGPRPLASDSSDSDSESDEDDLLKKAEIVNNKNSDDDTKFVGGEYDDTNDQPPEIGGALSSAEAEVNEIANEIEAILKLDESGKEKGIPSDTAKTGDTTADSPKAPVAATSSENKETAPAKEQASADTKQDKPKVIERPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU00</accession>
    <name>A0ABR3YU00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="30688" checksum="180877BB873E7D43" modified="2025-10-08" version="1">MTSKAETPFQGNEHDCYYETDPRQNHELASSLKGKNIVIAGAGRGIGRTCAEFLTHASARSLTLVALELNELEDTAEACRRINKDILIKVAAADVCDAGRAEDILAQVDRDFGGVDVLLMNAGRPPQWLPTAESDPAIWWSTVSVSLQGAFNYSRFALPTMQRKKGGSIIFTSSVGAHSNFGMASYTIGKLGMDRLCEILHQENFKEHNIKVFAYNPGCVRTRFFTDFVDFLDDKPIEGSYVVKGIPGERQSAATAKKTLSGATFDTPELAAGLVTALVAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU24</accession>
    <name>A0ABR3YU24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007649</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="4">
        <location>
            <begin position="72"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="203" mass="22006" checksum="5F6B1D7CDC35E76E" modified="2025-10-08" version="1">MAGSKMTNAERITKLLEMISGLDEAGMKDFTSSFIPHLTLVSADDFETAANHHHPPRIVFGYTVQPEHCNRMNNMHGGATATLFDFCTSLAMALAPSSPREATTPQTDAAGNVADDDSSDDDEEDIIKSWRRLGVSRTLAVTYVRPAPNDAQVLIECEQVHAGKRLSSLRGVMRRAKDGAVLATCEHGKVILDLADVPVPSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUG5</accession>
    <name>A0ABR3YUG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30577" checksum="B4F7CE7F3D624DF5" modified="2025-10-08" version="1">MVLIDFVRHAQGFHNLCADNLRMPDPLLTPLGEEQCATLQQTFGAENHSKVKLLVSSPLRRTLQTTLLSFAPVSERGVRVLAVPELQEVSAMPSDVGTPRSKLEKETNLFPADKVDLSRLHIGWNNKGPGSPYAFALPVLAARAKSARAILRVLTKGLGDEDRVVVVTHGGFLHFLTEDYEGVDPGRGTGWKNTEWRTFQFVSEEDENASLKETAESVKRRAGSEIGLTTQEQIELAAVYHGFLAGEQAHWPKPRPEDIRDYETALRDLQEVEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUT9</accession>
    <name>A0ABR3YUT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family 17 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="46398" checksum="7ED8DD373C2782F6" modified="2025-10-08" version="1">MRLLVPAPLGPGRAIRTYIIVLAGLIVTWCLWNGDTGAGVYDLGPSGKSNIDSLASANAVCKAHGWRPFVPQKYHGAAPRPRKVYDLCMVNAELDWLEIRLNTTYDEVDYFVIVEGAKTFTGLEKPLTIHDNWDRFAPYHAKMLYHELQYPANFNPPRAWDREDLQRNAMFLQVLGPGATVATPDAKIDVSKPGGGIPLEALPHQGDVLVVADVDEIPRPETLRALRLCQFPRRLTLRSQFYYYSFQFRHQGPEWAHPQATFYDGPGNTVLPVNLRNGDGRRGGDAKSLIGRLFQLIFAPFTIWARHEDTADMPNAGWHCSSCYATMGELMHKLESVSHVWMNHEFFRNKERAAHHVRLGIDLWDRESEKYDRIDNNTDVPSFLLAQPDRYRYLMNRDGDSAGFIDYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVG6</accession>
    <name>A0ABR3YVG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007097</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="66"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="423" mass="47139" checksum="DAF1F00210F28DE8" modified="2025-10-08" version="1">MAIASPPLGPSPPIKKSRIGCSSRLFPTGGFEVIEPSLQVEEEKLPTYDSTNYYPMRIGDIVDGHYQVVAKLGYGGTSTVWLARDLNKERLYRALKVHTHNAAYHHELSVYEHLKKPIQQEIDDKDSHPGRDHVRQLEDYFMLDGPHGQHAVFVMVPLGMSLATMQARQRTGVFPPILVTQALSQALLGVALLHSTDVIHTDLHADNLLIALTDESILSTIEESETTKPSPRKQAGDTTIHVSQYVLGGAGALTISDLGQARIGRVHTGNAMPIQYRAPEVILDMPWGAPVDMWSAGMLVWTLLEPKSLFHIYDTKSSPKLNDAHHLAAMTALLGPPPKEFRDRSKESIKYWDLQGNWQGPVPLPPKTQLADLVTTLEGDQKALFVDFLECFLTWLPEERLTADQTYFHSWLRGYDENGGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVI5</accession>
    <name>A0ABR3YVI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007126</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF18">
        <property type="entry name" value="MALTOSE FERMENTATION REGULATORY PROTEIN MAL13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="99"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="536" mass="59618" checksum="B92BDA4C86FB70F6" modified="2025-10-08" version="1">MPTPITPEEVDPPKLGPPPVYRRQPVEAYCRFLHVFRTRVYSVWPIVSCDSLERRLVEDDTTKDENNYDYEAWTLAAAACAAVIAQLRLPEHLPEHFPNSSSSNSVSSRFAADAEHFRTRTRHHSGYDAREHISVSSLLASFFLHIYYANAGRLRTAGLCLRESLTQAHMLGLHRSDTYTYGAMPDDDRELRLRVYWILFVSERTYCVQHGLPPILRPIRERPARSSAAVASLLDLTRLFTFLDGDLIEPEAMSSSNIVLHKDDGNDRQTRRRVALFQSFLDMDPSTTAAEKQPLLQGNGAEIDVDETQHVDLFVTRNWIRILLWEYSVRNFVMSSSISHTSSLSSSSSPEHNNQAFSMLLPALVAHSMLGFFSTISPESIRAHGYGMELKVFRIADSLLDVLACNSGSTDGGMLFGSRDTLHGLERVLATVGGTDSVFVSRLHSRMAEVQLPVAAAAPMLLWPVATDEPTASVQDVTDDNTDLSTLILSLQETETHTDASVPGIGLVDNFDVNDVLAMDMDLSVLDGDPFIVGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVV7</accession>
    <name>A0ABR3YVV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GPA1</name>
        <name evidence="10" type="ORF">Sste5346_007143</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="353" mass="41132" checksum="83BF528AA752F60E" modified="2025-10-08" version="1">MGCGMSVEEKEGKARNEEIENQLKRDRMQQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIYSNTVQSMRVILEAMESLELPLEDQRMEYHVQTIFMQPAQIEGEVLPPEVGNAIEALWKDRGVQECFKRSREYQLNDSARYYFDNIARIAAPDYMPDDQDVLRSRVKTTGITETTFIIGDLTYRMFDVGGQRSERKKWIHCFENVTTILFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFIKTSIILFLNKIDRFKEKLPISPMKNYFPDYEGGDDYAAACDYILNRFVNLNQHESKQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA6</accession>
    <name>A0ABR3YWA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Er membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726:SF2">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08426">
        <property type="entry name" value="ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046027975" description="Er membrane protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="55816" checksum="D7700601648F5EF2" modified="2025-10-08" version="1">MWWIFRVLLSTIFLLSVVLSIPIAFDVGGRDAGLAYSLALFLYYSAYSSIKIAVRLAAPDDRASSQRLRWTVAATLRLSQWVVIPSLLIWSLSRFSIDSSSTDWVARTVAHVTGGESGASKVVSSAISGSTTGGGGFGISNFFGLISRGASSASSISASASASAASASASSSTIFSSRPASTSWNDWFFGRGGVVESAALGGWDASLRYSSPIFQVLEGFCTLLVIQAAGQITRWLVNRGRSDSWLIILVVFSGSVIASAVYFLSRIARFPQIDNIDAILIGVTITSAVFLSAYGIGSGRGNPVESSLLFAYIVLCVYQIFTDYQPSSPEAAERRRLQQQQAAALEPEFPPLPPIIMASYSTLVHLLSSLPTAVSSALHFLHAAFQTITPSVIISLTYRIIVFYCATRIIPAVRESGARALLQEPTLEDSDAASKLLGFLSWYSASILIAIYTSLLLQHFTIASNTAGHDAGWSLLRAGEIAGGTTMRWVNVVGVMVLYAVELYLGNDENDGLTNHWKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWF5</accession>
    <name>A0ABR3YWF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Calcium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CCH1</name>
        <name evidence="17" type="ORF">Sste5346_007565</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="532"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="664"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="727"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="760"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="799"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1029"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1072"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1114"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1160"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1286"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1367"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1399"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1429"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1485"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1578"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="1623"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="139"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1845"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1854"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1897"/>
            <end position="1913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1891649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1943" mass="217223" checksum="D1372FD4E517277D" modified="2025-10-08" version="1">MVRRPDEFDSGYAYAPADAGLPPVDTYPSNSHSPYEQNPPPRPPISTSTNLPSITTYWADPQPSAHQSFLYGAPQHGNEPVSPESPIDPAALQFALPPNIFQTGPTTDDHDFEPPSADAFAAISTAYYDDHGHFDAGSDSDRIPLTASAEPISGSLGVPPDGIQSRDSFQTVAGSDSGQAQARDSRMLGFDLEPGYAAGGRQRSYGSSLAPDSASRRSRATSTSGALQKTASIMRAMSQRVVDISGGGEALEQQALRDRSRSPSTDGQRSHHLSAPMLVDTSYQQQAFGTPLEKKAESEFTISQPPPLSDYRPPMPNPLRGKSLGIFSADNPIRLWLCDLLMLPWVESLILVLIVLQAVLLAVEAAPDVWSPGNGRPERWGKTPYDWAMLGLFVIFTLEIMVRIIVSGFIFNAAEYSTIDRKRGMRQGVRAAVTDQYRSFFQPQRQRSVKRPPVETYGPSSFARSFTLMQGQPLPETYEEQQRMQLARRAFLRHSFSRLDFVAVVSFWISFVLGITGIEYRDLMYYTTNSDYLAAALFFAAGIMIMMLWMTNLLIAVITSSFQVIREESKGSAFTADEKEFLTPRPDNRLRRATVLQRVYKKTAWVWVLAIAFDLFVQAFRSASHENRISFINTCEIVVTILLDVEMVIRFSSDWRRFHHNIQNLFDLALAVVTSVILIPPIHNATQVYAWLTAFQILRAYRVVLAIPMTRTLIKLVLGNATGIGNLMLFVFLITFLVSIFAVQLFRGEITPQDPSGNDIRITFASIFNSFLGMYQILSSENWTAVLYTVTGFTKRLDTAWIGAIFLIGWFILSYFILVNMFIAVIQENFDVSEDQKRLEQVKAFLQRRELGTSASNLSLSAMFSLGRRAKRKDPLDYGPGMMEMLLKEAVVREFLNEALDPLQDPSTGHQTSSQVQDVLGGTAKAGVLPTIWAKMSRWTSSNDPNPFYSNVRFDVRNENLDPRQMAREAVSATSARRKAQREYLGRHPTYNNSLFIFTPRNPFRRLCQRLVGPGRGSERFDGVEPNKYAWYTFSAFIYASIVAMVIIACVTTPLYQKQYFDAGHTFSFKNWFVWTDMAFAVVFTVEAVVKIIADGFFWTPNAYFRSSWGIIDAVVLITLWINVATLFANDGAVSRAVGAFKALRALRLLNVSDSARETFHSLIIVGGWKILSAAFVSISLLIPFAIYGLNLFRGQMVSCNDESGSILRLQDCTGEYLSTPFSNDWQLLSPRVAENPYYSFDDFGSSILILFTIVSQEGWVDVSFQAQSVTGVGNQPQFGAAQGNALFFVVFNLLATIFVLTLFISVFMRNYTEQTGVAFLTGDQRAWLELRKLLRQISPSKSSYDESKNRLKQWCHKRAIEKHGKWYLGITMVLVLHLILLILEYSTEPDWWTNTRDYIFLFFTLVYMANISIRIVGLGWSRFRRSSWDVFSMCAVAGAFATSILFLAEPGQDTFIQLHKFFLVAIVLLLIPRNDALDQLFKTAAASVTTIGSLLATWLVFFLVFAIAMTQSFSLTRFSSQETNNINLRTVPNALILLFRMSCGEGWNQIMEDFAGVEPPLCVEAPTFFGSDCGSTAWARVLFIAWNIISMYIFVNLFVSLIYESFSYVYQRSSGLADISRDEIRRFKEAWRSVDPNGTGFISREAFPRLLGELSGVFEMRIYDHEDSVRSILEFARNDETTPQARHASLASQSVLTGVNLQKLNERVNQIDINRVRERRRRFNIFYEEVMVSADPDKGIFFTTVLMILAHYNIISDSKSLRRHMEQKRSARMTGIPQLGIPDILVDDEDERTAGAEVGQSAGAAVPSQAAATLLSAEHAAGSAQHHRSWSGASMDISLHDTNYAHPLSAPRTGGLSSPTGSGGLQPQRHQHNSSAFSFELQEPSAQSAADGSRRGSAVSAMSGVSGVSGVSPGLLREMLDDSVWVESIRRSATQRRSGWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWM2</accession>
    <name>A0ABR3YWM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DAL81</name>
        <name evidence="6" type="ORF">Sste5346_007201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="72"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="338"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="735"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="770" mass="84243" checksum="1B333F8554C593F2" modified="2025-10-08" version="1">MSNPSAMARTAPIPIAPKPSSSSTPSDPVGRTGFSGLRRSLPPSRQGSINVDSYPASLAGLDSPDSDSPRNNYATIPCEACQRRRIRCVMSEDDDICISCQVNQIECSHSGSPQPRKRKLGGDLDDNSSKRGLSSTAVSNSLIEDMANFGDVTMLKRTLGLQQDRYSQYIGPTTDFEPSLINLSSFDPHDESLLSRGTLRKVSDVETFLLLPDQNTPGFEHISEDIDEIERIVAPNGRRLVDLYFRVVHPSFPIIQKTVFYEKYDNALRDLQPPLLAAIYILAINWWDLDEELSNQARPNVPELERLVRTTLADSMFRPKLSTVQAGLLLSQRPEGDQWAPTAQLVAIAQELGLHLDCTNWKIPPWERGLRKRLAWALYMQDKWGALVHGRPSHIFANNWAVRQLLPNDFQDVEWDEDDTEERIEIERGRTLFVQMVQLTQVLAEILDTFYTLQAMQNVTAAGPQGTQLVLTLAKPIQLKLKEWYSALPAAVRMDSSLSSGGSTSINGNRLSSIGYLHLAYFAAEITLHRRIIRSMTSPTDSAASTPQLASSPTMLSNSSSAANLSSSAGGAEPYVQHICRSAAKARLISAMDFVNRLTPSHLRAFWYFASKTNFALIGTFGSLLWATSPGREEADWYRRRLGEYRWTLSVSSKPGEGKGLTNFAMGMLDISTGLLKTLPEKPSFSRSASVVDMDAARRQSILALGVSAAGLGSGATSSSFGGVGGYGSSFGGLHSTDASNAQSPKSSDDSSDEGVYGNFGPSGMANIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX30</accession>
    <name>A0ABR3YX30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="3">
        <location>
            <begin position="52"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="185" mass="20990" checksum="FCA3B303F7FB6787" modified="2025-10-08" version="1">MSQDKNSDQPRLRAQQHEHIDHTSTYPQFDYNTPIKYQPCIKISLFFNKRADVSYDHFYKHWATVHADLTAASHAFKKYNVLRYTQHHCTPDMQARVPQLGVAILDYDACTTMWVRDWDDMVAFHASDDFKRMAADCAHFLDLETPGGLRAMAGQDVIVVGEPIPGVDGETGGVPSSETGQGWRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXJ2</accession>
    <name>A0ABR3YXJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein-sorting-associated protein 60</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS60</name>
        <name evidence="5" type="ORF">Sste5346_006916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF12">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="28"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="215" mass="23754" checksum="E0C3118C1D3FE089" modified="2025-10-08" version="1">MQRLWGTGGSKAPKPSLNNAVTTSNDRIEALDSKIATLNAQLTALNSKMANMRDGSPGKTALRKRAIEVLKRRKQYESERTNYEAQVFNMERFQGMTDSMTNVRTTIAAMESASKDMKKQFGKVDLDKIERLQDEMADLMDVSNEIQETLGRSYDIPEDVDEAELDAELEALGADVELEAELGGAVGLPSFMQDEVPEFIDEAPQTDGKVKEVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXS8</accession>
    <name>A0ABR3YXS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006738</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058846">
        <property type="entry name" value="PAS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF30">
        <property type="entry name" value="TWO-COMPONENT SYSTEM RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26131">
        <property type="entry name" value="PAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="719"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="799"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1249"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="439"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1213"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1399"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="228"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="502"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1149"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1161"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1213"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1399"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1432"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1452" mass="154312" checksum="7B0DD5AB0B72503B" modified="2025-10-08" version="1">MTPPSPAIHGPDPPPGMTDVSTAAASSTATTSTTTTRPTSRPTTKHDAYNAASTMSHTQPDGSSRIPRTVALPSPSALAKSPNSLSPSPPPPQSQQQRQTPTTSADPSATTSHSPILSLPKISFIDLLEVDPRPSFVVSFDSAGPAIVYCNPALTTSSTLREIISAPRASHAAIWDGITANSGSALPAVSHLGHSWTQAVLGAGPARYIVISANQLAPASVEGAPAPTTTPVAPAISTTPAVSATPPPPNPLIVSTQPPTRPSLSRSASTPTTTPTTTPTTKTSKQPLLPLPEPPTPPASAVFSPPEEEASLGKATNTNDSKSKASLDSDVPEQNLAAAPAQVADSPSASTTSNYIPQFESITSFMPVGMSVFDAAGNVSFANRAWYHIMGCVPPETAQENEDVVMSRAHFLACVDEDDQDSVQRFFAQAASVQNRTFGFRVKKRGQQGATTGSTAATPSPSPPPVSSPNDGLPPTAEEGDDIDMTTPKKPASLLSMTSSKTATPTRIPTPSTSTVTAATATTTATAVDSGRDTPLRRNSLAPSSINEKEQPHGSRVLATGHWETDGQGRLVRILVCLRDITEHQNIAEAADRHAQQANNLRRMAEFATVGMYDMDITGRLRGANRVFYEMCGLERRVGDDDAEIDEEFMQPWLKCVVPEDQPLVQRCLDRLVSSVKHTNSFGSGSGSGSGVWEITEGASPGETTTHAIEGGDPETDHQTVEVRFKTPWTADDGAGGRIVAPRWVEASFLPVKDSDGKVQSVTGCLSDISLRRWQLERERQVKEEAIESKRQQENFVDITSHEIRNPLTVIMHCGDAVLECLSKLRDDVRAVAGPVSNTRQRALAMLDDGIDYAEIIVGSALHQKAIVDDILTMSKLDSDLLAVTPVTVDPIEIVRSTLKMFEVQARQQHIQLRMAVDASYYRDLPASCLFPAPTSTSATIKSSSISSEPSPALTPAAIPFLVLDPSRVKQILINLLTNALKFTQIVDIREVTTTLSVSRTRPTDAMCHVSFVPPQPDNKLAPAYNYPGGGANSPMGESVFLIFEVKDTGEGLTKEGMESLFQKFVQAESNTHVKHGGSGLGLFISKRLAEIQNGAIGVASAPGVGSTFVFYIEAYIPPSSAVPEILSPGEAAKIALAAGLGSVTGGLSASTPTPTATPNPKDDSNTSHLFESRPRSSKSSKDFQSLGRNSIDSTISGTGSIESRYAAATAAATTSPANAPSSPTPAEGESGEVGKLASVPATSPEIRGVLLVEDNIVNQKVTRRYFEKNGFHVQVAANGLEAMDIIQASDRRVPGSYPISVVLMDMEMPVQDGLTCTRHIRALEAAGAFAGGRMPVLMITGNARPEQIADARAAGCDDVVVKPFQMHLLFEHIKLVMQTLWEEDVRALDAVANKEVTEVSDVDDADNEKDNNENQLEMPALTSSTKQAKKKDHDERLDEGVVLRRQNSEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ6</accession>
    <name>A0ABR3YYQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="50"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="31364" checksum="278A0153C588C3A8" modified="2025-10-08" version="1">MAPSAVVLSNEEGANAATGALGKTKSGKTLKIRSYPKFASLHEERLYRKQHLAAVFRVFADRGFDEGVAGHVSVRDPILTDHFWLNPLSMHFSQISVSDLILVNEDGEVVEGDETINAAAFAIHSEIHKARPDVHAACHAHSVYGKAFSAFGRSLDMITQDALRFYKSHAVYDQFGGIVLDREEGKRIAAVLGDHNKAVILQNHGLLTVGRSVDEAAFWFLSLDKTCHAQLLVDAAAQGSGHPKKLINDEEAAFTYTQVGTPDKGWLSFQPYYDEQLAKTNGSFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ16</accession>
    <name>A0ABR3YZ16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Solute carrier family 39 (Zinc transporter), member 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006589</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045716065" description="Solute carrier family 39 (Zinc transporter), member 9" evidence="9">
        <location>
            <begin position="18"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="43977" checksum="CAA82A39B61E054E" modified="2025-10-08" version="1">MGGLLLLLVLCIVMALASFLAGALPLSMSLTQSQLRLISSIGVGILVGTSLIVIIPEGVEAIANPMLNPPGSVAASHVHDARHMSYLNSRSVPEAATAPSVDAGNVFADILYRRAKTEDEEAADGTVPAKSGDGETVTDPKKHHQGFGKSKQKQEGASATTPAPTDEPRSLPTFYIGFALVTGFVLMFLIDRLPRHFVDNLNSAPTTRAISLDNLASRGDSDESAEDDTFLGALAPTPRQSRGLATTVGLVIHAAADGIAMGASATTEDMKLGLVIFVAIMLHKAPAAFGLTSVLLKHGLSKRAARTHLGIFSLAAPFGALSTYILVKLVGGGDMEGERGQWWTGMLLLFSAGTFLYVAMQAMQEEAGGHDHHSLGNGYSDTATLAAQRKQGRPQMRDTLATIGGMLLPLLTQFGHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z045</accession>
    <name>A0ABR3Z045_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046147223" evidence="2">
        <location>
            <begin position="24"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="838" mass="87856" checksum="F22D0BA013DDDA25" modified="2025-10-08" version="1">MMARFTFLLPLAALLFAATNVFAQNCSSMGLDYTDGGSYLIDGSSNLPFTFNSMFEGCQDGFISPILVDPSGNQYACDDIETQPDDSQQTSKCDLTYDQMNSGLYTIILQSTDIDFASQREFQITVGNQGLVVVTVTPTETVGVTVTPTAVTEINEVVETQTVVGYPVTVTSYCAVPTQTVFSYVPGPTSIIDTVIQRWITSGTVTNFYQTTVGVNAYCHWPSTWHSPTSDRPPPPTSRPTSTRQCDGCRPWYTSGSWVYTRPSSTPTKPHTIPPKSTWHNTPPPPSSTRHDNPPPPSSTRHNDPPPSSTRHQDPPPPSSTRHTDPPPPSSTRHPDPPPSSTRRPDPPHSDPTTRQPDPPHNNPTTRQPDPPHTQPTTRQPDPPHTQPTTRQPDPPHTNPTTRQPDPPHTQPTTRQPDPPHTQPTTRQPDPPHTQPTTRQPDPPHSNPTTRQPDPPHSNPTTRHPDPPHTQPTTRQPDPPHTQPTTRQPDPPHTQPTTRQPDPPHSNPTTRQPEPPHTQPTTRQPEPPHTTTPPNNGGGNNGGNNGGNKGGGNNGGGNNGGNNGGNNGGNNGGNNGGNNGGNKGGGNGGGNNGGNNGGNNGGNNGGNKGGGNGGGNNGGNNGGNNGGNNGGNNGGGNNNGGNKGGGNGGGNNGGNNGGNKGGGNNNGGNNGGNNGGNKGGGGGNNNGGGNNGGGKGGGHKPDASEGVNEAPEATPTPALARARRALQKIQDVTSTVVETTYTATVTMTSTAPTPTSTEDDFYTVTETFVPPAQTVCNGNGNVPTVTYYYQGPAQTQYTVHYETYNTWATVWVGQTQYSTHTDRDAMTQCWQGGGRYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0R6</accession>
    <name>A0ABR3Z0R6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA-intron endonuclease Sen2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SEN2</name>
        <name evidence="10" type="ORF">Sste5346_006424</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006678">
        <property type="entry name" value="tRNA_intron_Endonuc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016589">
        <property type="entry name" value="tRNA_splic_SEN2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00324">
        <property type="entry name" value="endA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02778">
        <property type="entry name" value="tRNA_int_endo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011789">
        <property type="entry name" value="tRNA_splic_SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA intron endonuclease N-terminal" evidence="9">
        <location>
            <begin position="381"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="8">
        <location>
            <begin position="444"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="307"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="557" mass="59819" checksum="8D28D80E656DBF52" modified="2025-10-08" version="1">MAETKEPPLSGPASSSSSSNGAAAPLKASTDSVKQPPSSSTPTNAVRAPRQKYRMPLPLRTFPLPTFYPSNPVSLVHLAFAWVRQVLLPPASEPSVVHTGVWSAATRSVHVTDSKSINDLWSQGFYGKGSLSRSEPNWLNREKARAAAALVDAASAAAAGGFAVTSEQRTNKRREERADTKWERGRTELEAIEQRRREEEAAEAALADAAAAAKAKAKDVKEEEDKCHVGRASLPSPPPSPTAFKAPVGPLELLALPNSEADLRAPKAAAAAVEPTLHLNGSVSQSADPKPHVNGSANGTAISKEAVGENSAAAEPADAASTDSAPPVRPIEPLKRQKSVRFSPTVESTTFLHSDPPSPNHGASRAAVSATTDVVEDIPNKEHLQLAPEEAFFLAYGVGALRVVDEGGRTLSTKEMLAVCRESRVATSSSSTLFSSTASATDDFLLHYSVYHHFRSLGWVPRHGIKFGVDWMLYGKGPALDHAEFGVMVVPSTGPMPSWHWLHSVNRVLSTVFKSLVLVYVDVPPHTGEIDDISSLLSQYRIREVMVRRWSSNRNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z172</accession>
    <name>A0ABR3Z172_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PHD type zinc finger protein with BAH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SNT2</name>
        <name evidence="11" type="ORF">Sste5346_006308</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAL1893805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Homeodomain-like"/>
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    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029617">
        <property type="entry name" value="Snt2"/>
    </dbReference>
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        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
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            <begin position="383"/>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Z8</accession>
    <name>A0ABR3Z2Z8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">enoyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="11">1.3.1.104</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ETR1</name>
        <name evidence="14" type="ORF">Sste5346_005905</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22564"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.104"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.104" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019166">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08290">
        <property type="entry name" value="ETR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051034">
        <property type="entry name" value="Mito_Enoyl-ACP_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="13">
        <location>
            <begin position="62"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="424" mass="45129" checksum="6ED09E614862518E" modified="2025-10-08" version="1">MAAAFARPTRLPMRTATSLAAAWRPVARVQIPMLQQQMGGARFKSGPYGYTQAKALVFSKMGEPADVLSVHTHSISPTLPPNAALLRTLAAPINPADINTVQGTYGAKPTFSSLIGTAEPSSVPGSEACFEVVSVGSGVTTLKPGDWALPAAPGLGTWRTHALVEEADASLVGISKEKLEGLTPAAAATSTVNPCTAWRMLRDYVDLVELSVKAGQGAWFIQNGANSGVGRAAIQLGKLWGLRSINVVRARDTPEATAALKQELTDLGATIVITEEELQERGFSSGRLRNELMADKESPLLLALNCVGGRPALGLAKCLSDGGQMVTYGAMAKQPLTIPAGLLIFRDLSFHGFWFSRWGKVDPAARRTTVEAVLDLMRTGKFLPGPAEEIPWTWETETETLQKAVAGTLEGYRSGKGIFVFKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z392</accession>
    <name>A0ABR3Z392_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="221" mass="24550" checksum="9A77B134F1607930" modified="2025-10-08" version="1">MSKFVLSGASALAVTTNFAAFWQPATTMTPVHMSLLLPTTCDFFGRTAPFLEDTATSANNGNVQSPAEDDNSGEALFHPSLPKKIDDKAKGAASTIPFFAAHNRVSDELKFQMLRDNTVKDYFQSLEKVVVDGGSQLMLEDGIDGSLPELWEEAAVDEDLFLISSQWVSFAPGQQPSKEDLQKRADFWLDRVTQWPELRAFSPDILRKHLVEVIIVRDLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3F6</accession>
    <name>A0ABR3Z3F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ilp is an apoptosis inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053267">
        <property type="entry name" value="Verrucosidin_biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087:SF1">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="35749" checksum="4186BECB3FB87848" modified="2025-10-08" version="1">MAFNRAGGGFSFQQEQVAHSSFSYSDSNSPVPGTDSTNNRRAAPSSSSSTSTSSKTHQSTSPSPFTSSYYSASPLAARQQAYTYPSSYASSSSSTYSTRGHNVNSNSSPQPFVDAQFDIFEWHVQYQSCVRYFLDHAQYSAPVQAVAAFVNIQLPFQRPTHPILASQPRSGAPGASGGGPTSRSAAAAAAAAAVAGGAAQPTAFVTLVPYIRRLIATAFDFPAVLHGFFGDDWMAGIGPIHETERRNYLFAAKSDNWLKVKADYDMDENQTVPFLRPLQNVSEDEIVNAETTWSEWLAMQDWMLGPRAPSDIGSGGSIRGGRRVNIKREED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K6</accession>
    <name>A0ABR3Z3K6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949669" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="153"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="326" mass="33434" checksum="4CBA3AA5818C7869" modified="2025-10-08" version="1">MKASFALALAGSILAVASPIDKRAIHTKYVTDLVLVTVTVDPPTTTHKPTTHHTTTHKTTPTTTSIKTTSTPPPPPPPAPTTTSTPPPPPPTTSSTPQPQVITITEGANSPAAAATTAAPAVVAPQAAQAPAEVESSSPAPAATTAASSAPSDFGSTAVYHHNLHRSNHSAPAVSWDSDLADYAATVAASCVFAHDLTPGASTGSYGQNIAVYGASGDVSSIDPSKIVAQAITDMWYNGEVWQFPSDGYGESNPDMSNFEAWGHFSQVVWVASTEVGCASQYCSPGTIYSGMGSWFTVCNYRSEGNMGGAYGENVLPSLGEATVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3M4</accession>
    <name>A0ABR3Z3M4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Replication factor C subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RFC4</name>
        <name evidence="6" type="ORF">Sste5346_005376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="68"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="39375" checksum="5954D4D72EBD21D9" modified="2025-10-08" version="1">MPAAAAPVAETPGESSTSAAKKALASAANGTPNYELPWVEKYRPVFLDDIVGNTETIERLKIIAKDGNMPHIIISGMPGIGKTTSVLCLARQLLGDAYKEAVLELNASDERGIDVVRNRIKGFAQKKVTLPAGRHKLVILDEADSMTSGAQQALRRTMEIYSNTTRFAFACNQSNKIIEPLQSRCAILRYARLTDAQVVKRLLQIIEAENVRYSDDGLAALVFSAEGDMRQAINNLQSTHTGFGFVSGDNVFRVVDAPHPIKVQAMLKACHEGNVDAALDTLRELWDLGYSSHDIISTMFKVTKTMPGLSEHAKLEFIREIGFTHMKILEGVQTLLQLSGCLARLCKLNMNPKLFPPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z400</accession>
    <name>A0ABR3Z400_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="198" mass="22932" checksum="0B1755BC01BA64D1" modified="2025-10-08" version="1">MERLPGKPLSHDWVFRSGESRAKILAQLRPMIAELRNVRRPPPPPGYPLNTDIVSGIDGGQFYDGNLPNKRYWGPFSTVRDFHRDLRSNLMAVPDEYTEERFADLRKLISLHEGYVADPPVLTHGDLSANNILADGDTVTGIIDWETAAWMPAYWEFTNAWHVNPFNPYWQAEVGKFLKVWPAELEMEKLRRKFFDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4C1</accession>
    <name>A0ABR3Z4C1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Synaptotagmin-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SLP2</name>
        <name evidence="6" type="ORF">Sste5346_005203</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="105"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="454" mass="48059" checksum="E23C8B24BA6A5372" modified="2025-10-08" version="1">MATAMTRRALSPALRRGPAALQLASSSSKTTSISSALPRTITTIAARANTTQKNNGKTITSVSQPQQRSIQTSSSPLLSAIGGFGGAPSGIPAAYFQKPSLPANTIIRFVPQQTAWIVERMGKFHRILQPGLAVLIPFLDRIAYVKSLKEVALEIPSQSAITADNVTLELDGVLYTRVFDAYKASYGVEDAEYAISQLAQTTMRSEIGQLSLDHVLKERAALNTNITAAINEAAQAWGVTCLRYEIRDIHAPAPVVEAMHRQVTAERSKRAEILESEGQRQSAINIAEGKKQSVILASEALRAENINRASGEAEAILLKANATAAGIASVAAKIAQGSDAAHSAVSLSVAEKYVDAFGKLAKEGTAVVVPGNVGDMAGLIATALGVYGKVGQATANPRAAARQALEKGGVIEGDALANRDVEDAAQLEGLDPAERSKFVRDRIVEDFDRHTADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4D2</accession>
    <name>A0ABR3Z4D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="415" mass="43074" checksum="1098D3C2B5170676" modified="2025-10-08" version="1">MSYYEGSRPWPAVGQNAWNDLDIDSQTVRSGASSTVPSSAPPPPAQGQEGLPFYHQLDEVDRAVDNLVKSGKMFGVPGRQGRQGHMNNRPHSMAEFGDARGAHQSNLQNFYASQRHQSSRGSNEAEQVIQAKRRMAAQRERELRNYHQEQQYNRTMIAELSSFGNKPDRTLSPGSMSETERRDLIARQRSALYGEGSFAETGGYIDETGTPRPGVPGPLHGPPGSSSQRGPSPLAYEYGRAPPPGSAADGSVSKDGVTTSSPSIGATPRSRANSTASPQPNIGGSAPQQASQASRTNTSSPGNSPINGKPGSNVNQGSAVAPIGTRPSVSGSSSAANPSLNKRSTTPLASPQAHSGGFPPPGANGDNAPASGSSSNPSATTPDGSMGVSGWSSRGGSVWGNSSKPGMGVQASVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y3</accession>
    <name>A0ABR3Z5Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Translin-associated protein X</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005162</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32837" checksum="2554FB57EAE909CE" modified="2025-10-08" version="1">MAPEGKRRWQADSNGGPSDSPDHKKMARRGPPPPMTPAVRNAYTPMFEKFRDHLDAHHDRRERVVKASRDITALSKKIIFALQRVRRIHPDLPKDVDGEVNKKLAEIGKLLAGIAPEMQGINRGRYARVLFGMEELLEALTFLNYLKFQTLLSPEDAAEQVAALCVQGRADTVDEKDVLFIHPDDNEFLMGVFDLSGEMMRFATTSAALRGELASDGDDKAGRSIVGDMQELDSFFRMLPRRHDKSWKMKTQTLQSSVQKVERLGYDLRVRGSERPKGWIPDAPEANEGGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z610</accession>
    <name>A0ABR3Z610_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005636</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="288" mass="30000" checksum="FDAD7079BA79C4DC" modified="2025-10-08" version="1">MADRLSQIAGHLQSGKLLQNQTAIITGAAQGIGAEAARLFAEEGAKVVISDIDAAKSQATADAINKAGGKALAVPGDLLKQDYIEELVKKAAEFGGGKIHIIVNNAGYTWDGVIHKMSDKQWDNILDLHAKAPFRLIRAAAPYFRVTDGERRNIINISSTSGMHGNAGQANYSLAKAGVSGLSKTIAKEWGPKFGVRCNTVAFGHILTRLTQAKEKGAFVVGPDGEKIALGIPTAPASAAAEAQANADIALRRPGSATEAASAVLAVASPLFDYVTGQTIMVTGGRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z928</accession>
    <name>A0ABR3Z928_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_004614</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="79"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="500"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="560"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="752"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="865"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="949"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1044"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1251"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1278"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1693"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1818"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="589"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="701"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1076"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1496"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1601"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1661"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="867"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="966"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="993"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1278"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1295"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1701"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1721"/>
            <end position="1741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1742"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1818"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1838"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1875" mass="206138" checksum="A08BBCAD718C96A7" modified="2025-10-08" version="1">MEPLVASSGANAAPASSIPSAIDTHGHSPPSNLQQSPASPGLPRPMSVMVRPSPRSNSRMSVGSKNGGSRASDEDGRTSVKVAVRVRPPLRPTDPGYELIPQRFQRSMVQVNSDTSLAIDSPQGRKLFVFDRVFSPEVSQEGIWDYLTDSVSAFVTGYNVSLLAYGQSGAGKSYTMGTSGPSEQGDAEIMGVIPRAAAALFEKLEGAKPNGNRSSMSHLRAPKGYGASQAAPRAEKTWSLKATYVEIYNEQLRDLLIPESVPTHERASVTIREDVKGNIILTGLHQVEINSVDDLLNALNFGSTLRQTDATAINARSSRSHAVFSLNLVQRKNGFQSTKAEKRMSVPLEAMTGTESFVTVDSKFHFVDLAGSERLKNTGAQGERAKEGISINAGLAALGKVISQLSSRQPGSHVSYRDSRLTRLLQDSLGGNAITYMIACVTPAEFHLSETLNTVQYAQRARAIQSKPRIQQVEEGDKQAIIDRLKAEVAFLREQIRSAASNNSPSERRVMSATERSERQGEREVEMQNALLDAQENYSALSQRHAKLIAEMAKARDIEAAETQQHQLEEAEAGEDSATERLNRSNTFAHAVEQVVLEYEKTIQSLEQSLSSTRATLSNTETSLLEKESKCAYAETINTQLQARLQKLMDREANTENYLHDLESKLDGHTSGEEKNATIIIELRKEIARIRENEATCEDYISTLEERLAEADQDAELMQREIDRLEQVVERQRSLGKLDSLLYELDNMQQQDGSAGPGITSGVDGTEGGAVNGNGAAPNGIGHGHRRTASRSIEKHSRSLSHVSRHSHSHSTDVILEEDGEALEAAAPEIDATIEEEEGVEQEAEVDGGLAQDGEVVTDAEAEITEETNGAQKSVTPRPSQTSLRTAKRSESFTSPAQSKFVADKLEVVTQELVDLRVEHESTVTEFEMLHAKYEEALRTLAELQDAVDEARHPRQTVRDSILSVAETSQTRPSSYLSDARSSEPEKNRHYSSSRSLSSELSSALDSPATMEHSDAETLAPVKKGNRPASIDVAAAIAIPQVREIEPVQTEEGEEPKSPSANGRGLIMSPSSDSILEAEVERLRALAAEKEEAEKQLSGKYAELEQQHHQTLDMVEELKTEVAKAQQAAEVTSPRSSTPVIRRKSSQNVMIIDRAHRSFASLRNIATENFEGNPDVMQNFELNINAAMHELHARSERIQELEADVASTKKEMDTKMAIISGLTRERSSLKSSPMDMSVVSTLRDQLEKNENQMNQLKSAHTAREQELQTELESLRASLEAAATAQTESQSSAAREATEASETRDAQKASTAQEHADKVRNLEAELAGWETKHQTALSSMGETEKQMKEHIEQLESQLTAANEQLAESTKNAAAGDEESAAVSAKHEEQVQMLRTEVDEYKAIINSNAAKVAELEAGHASAKSALEEAVAARDAASTEAATHKELVSQLQTKIADHEKALATHQEGLETLHANHARELENLQASSRKEYDEEVQVLMTEHAENIRILESDLTEAREDLMKVATQVAFALGLDVSVEKITERIEDLIADQKALGVEQNKSLELQETVKELTSISDSVMRDLETVRATLTQVLGPDAEVSRKPNATVAEQAAAVQKRLTDLETKNKKHSRLVDELEEQLQTNFDQAQITTNRLSTLQSERHQQLEEVTSAKIRMQSELDAIREEYAALQARFEGILPADGSGAPQRSNSASSQLRKSSSVASLPSPPPAIPLPPLPGSSSPPPTANNVPSTPTTMRPPSKDIALHQIQQDQEARIRTIEKHLEAEKQLTQTLEEALTDLEEQSKKLKTDCDAWRRRAQDLENENKELKDKPAQDNRWSLHQVEEERKKRRDAEIARAHLEERMNAISKKKKKGSLNCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9I5</accession>
    <name>A0ABR3Z9I5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_004435</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="636"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="614"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="793" mass="88697" checksum="7558E86D0824816E" modified="2025-10-08" version="1">MSGDADSTWSDSHAMDSDDNRLASDVVLRSTTTWIRADSSSSSRSTLVSEISAASHFSAGQLSPISIGVDIPGAVSDAEHYPLTASTSLSSAPTLDNTTSLSSPTLENSTSPSSNSEPRDVYASGHDHSHAHGDHHDSHMNDHSHYNDAVHGHIDTASEMQWDVDMIEDLVIPKLEPMEDDTFRLDDLEEAPANPEPTDNTAPNASTKVKRPRGRPRKLSILPTAPTNPGKIAKGRSKTGCVTCRKRKKKCDEAKPRCMNCEKNAVVCEGYPEKQIWKSGKEKAEEELLKNQSLPVITMQPIFTGLETAEDRVFWRHYNDHLSAVFTVEGEHHNAFRDMLVPVATRHQGMMHSLLSLASRHLDYDTPYGAKILRRNARISIDSLHRRGNFHNNEAVKTLREGMQTDQMDDPEMTNNLAARYGQMLCLILEPLAEGDISGTQRLHYEAFLYLIQNNPPQDDTFHAFIAEIFYYHIFADDLVYYPSPPAKRLVTDDWAPTAPIQRPRLIGVADGLFGYLSQITTIRNRIRARIECNADPRVDYESLYRASDIEDQILEWKPEWPVGDSRERVTLLYKQMAWLYLKTTICPPTSVYSSVSMTRSFNSRTGGPITETPPHSVAASCASSPSPRLEAMVPQENHFNNPRRHSIANPSISGERRPFLNTTSDLFGQKSSNDNDIRSSPPPIRRPSNHEPGVSVAVEESLSLLESFLPSDPTQALLLVPCVIIGTSCYSPKEQERVRNAIRVVHGYTGLRNTFKAQEVLNEVWRLIELGDFLSAWDWQAVANSLDIRHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9V6</accession>
    <name>A0ABR3Z9V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pyruvate, water dikinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004183</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="4">
        <location>
            <begin position="38"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="3">
        <location>
            <begin position="856"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="937" mass="105074" checksum="C386BBCF707DBC00" modified="2025-10-08" version="1">MSSLVKVNGTSRSSTSSDSPARSEYALTFSDPGATEKDKVGGKGCNLGFLTQARFPVPPGFTVTTAAYVRFMDLSGLKPKILALVGAINYDNADDVEAKAATAREMVMQTLMPLELTSEITSHYAQLTGDDGDPFVAVRSSGTAEDLAEASFAGLHDTLLDIRGPEALIDAVRTCWASLWSARAVAYRHRNNFAHADVDLAVVVQRMVAAAAAGVLFTGNPMTAATDEMVINASWGLGEAVVSGIVNPDSFVLKDVGYSLRIRDRTLGDKTHTIRRHPSGDQSTGQGTITEDTPTALREAYSLTDDQALKLARLGQRVQEHYGGFPQDIEWALEGDNDLYLLQSRPITGVDFSWDADLEEWQMFPEIDGTTWTRSLADENWTGAISPLMYSVRAFSWAQGHECAAGVWGDPALQEKRYWKFHRATAYFNCDLERDVVRNTIPPMLRPGLLANLPVPWREEVSAATFSWFGYAKLYARVETLRPQLYKGFELQKNKWYGKFATEGKGIPRSELSSLSDTALRFYVNRQLDIEDEYTRDMWTWFFINARDMLTLLSLMLQMWYDPEDKTAFQAVLTGTPRASETMKANHMLWEMSQRIYKSPILSAAFFAHQDAAFFEACAESDDGRTFLEYYQGFLALYGQRGMPDRDIYFKRRWEDPSIDYRSLQAMLKTPDAPDPQIKEHETNERREAFVDKVFAKMQRSTLGLFKVELFKVVLAWCIEFVIVRDDERNFLDHCTLSIRWGFMEVGRRLAEYGVFESDDDVWFLSKQELYRLWDSRKMTPLVRAKIDARRRDFVRMMERETPLPPYIVDNKAADLDADPSAFEGAGIFKGIGTAKGDVTATARVVRQLKDIGRVREGDILVVNSTDPGWTPVFHIISGIVLETGGILSHGSCLAREYGLPAVQLARAMQFIPDGATVTVNGDAGTVHLAEEDVVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9X5</accession>
    <name>A0ABR3Z9X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Virginiamycin B lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051344">
        <property type="entry name" value="Vgb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40274">
        <property type="entry name" value="VIRGINIAMYCIN B LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40274:SF3">
        <property type="entry name" value="VIRGINIAMYCIN B LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24684">
        <property type="entry name" value="Vgb_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163234" description="Virginiamycin B lyase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="39002" checksum="929CEDB9842B681D" modified="2025-10-08" version="1">MKGTVLALTLVSSSTLVSAAGILGGLFPSKKGGIQEYAAVTLLDTACETEFHPDQLDIAWVELIASNTILRVNVTSGEQTRFPLKNPVGLPSGMEFLPDGYLWFSEVVGNSMIRLDPKDGSMTEFPFPLTGIAAVDDLPAGIRVTIDVSGNRDRGAWFTAAGLNAIGRFDIDTFEYDIYPLPNLLSVPLIIQGGPGSTMVFSEIVGNRIGTIDVNTKEIKEYEIPTPLSLPQGVTVDKDGLIWWTGTGSGNFGTIDVTTGEVTEISIAALRAAGNSTVVGDPSIGTSAALSFPGPIRVGNDGKVYFVEGNLVFLGNRVAQYDPKTRQLVEYTTPTSLSAPCDLNSQHSDSIYFAEFAGAHLGRLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBU3</accession>
    <name>A0ABR3ZBU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Spherulation-specific family 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040:SF9">
        <property type="entry name" value="4-LIKE CELL SURFACE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045597549" description="Spherulation-specific family 4" evidence="1">
        <location>
            <begin position="17"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="32576" checksum="C1EBF4114C6FE9DD" modified="2025-10-08" version="1">MKSAACLPSLVGAASATVGLLVPLYEYPSGTAATTDWTALIAAVDAHPQLPFYVVINDGNGPPYSPNPPSSMPDWAQYIDALNSRANAKTIGYVYTSQSTRSYSDLTAAVDQYASWTTSAGFTTNASRYDIHIDGIFFDEIDTVPTKLTNNTQLTTYAKTKFAERGGPIVLNPGTLVQAGSESLFDLADSILQIETCYTKTEGATDPGPILRCPSGGYSPFTPALAATVGNASQSAKSSIVVHDFYETWSPFVPASLSTLQTDIAAVIKQGVHSFYFTTYGYTTNFTASPASITQVADYAAQLQGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBV8</accession>
    <name>A0ABR3ZBV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="159" mass="18467" checksum="F2BBF0FDEEE35CFF" modified="2025-10-08" version="1">MSIPNRQWFLDYMRAFNAHDFDKQYSYYTDDVILDIPDPQTGTLRGKDGIKAHYMPLFGVCEEIVVPMVLAIEGKHIFYIMESYFKYTKKMEKGVFGYPVDVGDVVKIRVWAHYQVENGLMKEIVCNLFKSEFLPQGNLKELVLESQSRAQPDLCLPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCZ2</accession>
    <name>A0ABR3ZCZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">S-adenosylmethionine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PET8</name>
        <name evidence="11" type="ORF">Sste5346_003767</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="87"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="180"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="280" mass="29249" checksum="5148DE67C98BE9B2" modified="2025-10-08" version="1">MDYSTALLAGAVAGTSVDLSLFPLDTLKTRLQAGPGFWASGGFSGIYRGVGSAVVGSAPGAALFFVTYESVKHALGHNTNGPSFGSGSAYTHMLAASLGEIAACAVRVPTEVVKQRAQAGQFASSAQALAAILRGPSVFSNLYRGWGATILREVPFTVVQFPLWEAMKAWRRGTKNGQEVSAFESAAFGSLAGGIAAAATTPLDVLKTRIMLSTERQSLATMVRSIMAEQGASAFFAGLGPRVTWISIGGAIFLGSYQWVVNFVGTRHGSNSDDKSRIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCZ7</accession>
    <name>A0ABR3ZCZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="515" mass="56493" checksum="DE9376A95F287CBB" modified="2025-10-08" version="1">MDNMFDEDFFDDDLFADSAECSPITKAELEEAYLFDTLVESTTIKLVARIEEDREGDARTTTEQTITGDGPVVFSTEVFSMDRLLWADGVMLPNKTDKAGTTTAATKATFAVFKVNLESHTKSSGSGQNKAVQSARIQVEFHGTGPDADTVRAQRPVVVGWAPFATAEKSNMTKAEKTRIRSMRAGLQAGASQAKGTIEGTASSKRVWTKSYFDVNRSRPVSILGSTGESSNYNGVRWEMEHNRLAGEGVKPELLLCLLVTRQDDREYSVKITANVDNTRLLGHKEHKCVLRVTPRDPDNDTEPAVCYLQGKKMWQKLDVDHFEALLSPNMDSSLRLPWDLEDMAGTEDAKSGKSGAAAKNTKAGTKNGKDPENEAAEDRDGEDDDEDDDGNDSEGGDGDASESNRDENEGAAEAEPNATLTAAVSFAKERSEGSADEKAPRPARRQYEVALLDDPAVMLDTLLGLSAGGSSSHDKDEEDVTARMEMLESRMELMEFRMARQALLIRALLKHRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE13</accession>
    <name>A0ABR3ZE13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase PEP5</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">VPS11</name>
        <name evidence="14" type="ORF">Sste5346_003294</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16688">
        <property type="entry name" value="RING-H2_Vps11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016528">
        <property type="entry name" value="VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007860">
        <property type="entry name" value="VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="CHCR" evidence="11">
        <location>
            <begin position="420"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="918"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="945"/>
            <end position="966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1023" mass="112025" checksum="6E1EDE49E85EBEDB" modified="2025-10-08" version="1">MANSWKSFDFFDVNQARPGDDEARSFFESNEIASVCSGSDSLFLGSFDGYVRIIGPSWKIVRSFLAHEAGSITHMRQVEGTSLLVTVAEDLSVGPVLKVWALDKPVKKTGLPTCLSTIQINNGKKQFPISAFTATPDLSQLAVGFANGSVTLIRGDLVNDTGTRQRIIHESEEPITGVELDVDEKLTTTLFIATTGRILKLPILAKGKAQPPKTVEDTGCAVGCMTIDRRTGDIVVARDDAIYYYTIDGRGPPRAYDAPKSLISVYDDYVALVSPASALGGSGGDSGGASGAAGGGNALRRRFGASAAAADVLFNTSTFALLETDLKVVAHSETLLSPVKSIFQLWGSLCVLTLDGKVRLYREKSLQQRLDMLYQRNLYHLAIELARKSGLDGQQQNIIFRKFGDYLYQKGSYDEAMVQYIKAIDSTEPSQVIRKFLDTQRIHNLIEYLEELHEHHRATADHTTLLLNCYAKLKDIDKLEKFIKSPGDLKFDLDTAISMCRQGGYYEQAVYLAKQHSENDLVVDILVEDAKQYDDALDFIWHLDAETAYTSLMKYARVLIEHCPKDATQLFIDYYTGKYRPKLDVPTSAGVAAAAAASGGSGFAYGAASAVSNLAGRITLPYLTSGAAATEEQKAAAAAAAMAGAPATEAGITQAEAALLAYKVPKPRTAFSSFIDHPDEFIVFLEACLREKKPLADDDRTDLYTTLFEMYLQKSSEKKGDQNREAWEAKAKALINKQGSGEDDDDDDTPVPIEKANVLLLSHLSNFRDGTTMVKEQAGLLSDIFRSYTSAKDTRGALKALHKYGPEEPQLYTAALSYLTSSARVLDEAGPDELAAVLKRIHSDGLMAPLQVVQTLSQNPVATMGMLKPYLQETIERERREIAANQRRISSFRQETEQRRTELADLESKPAVFQATRCSQCALPLELPVVHFLCKHSFHQRCLKSDGGSASGMSSPRDGDAASSSAECPLCAQDNATVRAIRRQQEEYATRHDLFKTELGNSEDRFGTVADWFQRGVMGPAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE41</accession>
    <name>A0ABR3ZE41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">mRNA 3'-end-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">YTH1</name>
        <name evidence="15" type="ORF">Sste5346_003421</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="259"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="361" mass="38404" checksum="5F7C0683B5F37E6E" modified="2025-10-08" version="1">MAAAVQRQGADSPLQAASTASGRLAAGMLVRGAGSAPSHYTFAFTPFLQTTYKHGLPGDRPVCRAYSTTGSCPLGSRCPDRHLSPAAAAAAIAAGAIYTPIGGSGSNNPHHSGGRDQGGFNSLVCKHWLRGLCKKGEGCEFLHEYNLRKMPECNFFLRNGYCSNGDECLYLHIDPRSKLPPCPDYDNRGFCALGPTCPKKHVRRKAICPYFLAGFCPEGMRVCKEGAHPKWTPVAIVAPQVAAEKAAAEVAAAEAALRGETLDENGQAGSPFAGGDDYNMGGTDSHQQQQHDGMDGQNPYQQQHQRQGHHMDGGDDVSSIAGSDRTQGSHRGGFRERGRGGRWRGRGGGGRGFRGRGRGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFC8</accession>
    <name>A0ABR3ZFC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047522847" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29440" checksum="67350455B8153E4B" modified="2025-10-08" version="1">MIPKWVASVAMLSLFAAVAMAKPVGRGSSTDTTTVDTSSKGTPALMANIWTGYLSDSKEPTTLYGNSVEDIIVQIHRYVPAYATDNVASEISYNEFDNGTPEDLPDIGTPPIEWRGPGGPWFDYTKNGITYNYTCGMEGTADPGRTKDGAHKLRNMHNDMATTIAKTCARQWCYDTTAMYVCNWTDEDLVIPYYNIGWMTDGLDRLCCDDDYGKSGQMWHYRLPYSVVLGFGDCNEDPDLSPPYPMGAGNNGMCNAWNTTIWEAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGF7</accession>
    <name>A0ABR3ZGF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0045 protein M15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ECM15</name>
        <name evidence="3" type="ORF">Sste5346_002627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051614">
        <property type="entry name" value="UPF0045_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00106">
        <property type="entry name" value="MTH1187 family thiamine-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777:SF1">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="MTH1187/YkoF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine-binding protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="112" mass="12087" checksum="9AF73C2EBD8F4BE6" modified="2025-10-08" version="1">MATDYSTVPTPVACYADFCLIPVGTGNVSVAEDVAEVQRLLQASGLTVTMHASGTTVEGSWDDVMRVIGQAHTVVHQRGVLRVQSSMRVGTRTDKKQTAADKVKRVKDILEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH03</accession>
    <name>A0ABR3ZH03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Member of the karyopherin-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PDR6</name>
        <name evidence="7" type="ORF">Sste5346_002875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1013" mass="112388" checksum="9BFAA023CF4EC293" modified="2025-10-08" version="1">MEHHNPLPTSIDEVESETLQRLQKSPEGWRLAQTLLDRPVTSAAGDQVKFFGALTIIVKLNTESSSLSDEDASELLQNLLCWLASSAGDQAAGLSTQKVWQALATFFIHFPTLWPNCVKSLLVCLRTGHSVTHEDVERAPSVAEIVSGLDWRLLRVALGFTNTLVTDVGKTDMRIPKFSLVHNRLLHNASDVSELIHVGLTSTSQDYITLRRESIRSLQSWILYAQRLPAGGDVLVGPLRNLVNPVIACLQDEELYEASIELLIDILSNYSNFFTAEHYNAIAQIFESSWGAERLQQLLGGDFDFEPLQYGLLLLAYGDARVETLMQSSDERSRNILASLSSLLTAKGHPVAEDFIFVPALEFWATYIETMLDTMYSSENKYEPWVNSALVLVKEVVGHCWEKIQYPPVKEFMSWDSSDRAGFIDARKDVGDLLQTVFTAAGGELLVIFTDLLLRSIEDKAWAQIEATAFCLAALSDCVSDDDSYDKILERVFSSPLFGLLALGEQQLPVRLRQTALSLIERYSEYFERTPEHLPAALTLLFEAVATPTLALQASKSIATLCSSCRSLLTSEVNAFLHQYQLLHDNPQLDSLAEERIVNAIAAIIQATPDENTRLQLSEQLLSYIVRDAELCLRLSSDISGLDSNTPLMAKAIRQCEQQLQEGQSSPSVNEVLLQAVLIPLRCLFGMARGLQSATEHHVDLDSDDNEAGTSKSLTNAQNNPQLQALQTHIMTMILSIQAAFPKSNEVIDVICSIFKAGFSETEPGPLVFPPEMVTEMLVHQNAQTPYIGSIVNTAHSFASSLAKHPSKEVANKSLGALVPWIFGLLQALPEPDADTELTQRGIEFIDRVMQKNASALLRVEPSSQLEFFFMFTLKVLDGREPLPKGASADFWTTFLTLRLDDPSLTAIVTNAMEHLGPLLAKSLIYNIGGNASRSELDKLGEPLKKMVVQHIRANTWLEQALMSPSFPSDRMTASDKTFFLKKIISLRGARQTNNVVREFWLTCRGSNFAYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH40</accession>
    <name>A0ABR3ZH40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPN9</name>
        <name evidence="4" type="ORF">Sste5346_003050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040798">
        <property type="entry name" value="Rpn9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18261">
        <property type="entry name" value="Rpn9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="173"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="383" mass="43651" checksum="25F182EBB24E4BF8" modified="2025-10-08" version="1">MSAEALTDFLDEQRDAAPAELQGAILEIENLWERKLWHQLTDALLVVFNDEQSEDLRLPFFKVFVLKFADKINQLKFVDLALKAAESCKDDKERLAFLESVAKRVDHEDSQDAFVFATIAVARVKLSLRDFDGARSDLDNAERVLDTFDAVENIVHAAFYDTSSLYYQAKLDFALYYRNALLYLACVDVASLDADDRHDRAYKLSLAALVSSSIYNFGELLLHPILDALTTEDEDDAWLRELLFAYNRGDLRAYERLSEHIAGNSLLNKHSGQLRQKIYLAALTEAVFRRPPHQRSMTFATIAQETNVQPDEIEHLVMKALSLGLLRGTIDQVDEVAHINWVQPKVLDMKQIDNMRQRLGEWGSSVNQLGNWIEQVGQDVWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHQ4</accession>
    <name>A0ABR3ZHQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">POT1</name>
        <name evidence="16" type="ORF">Sste5346_002708</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="14">
        <location>
            <begin position="33"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="15">
        <location>
            <begin position="297"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="418" mass="43418" checksum="A4E4A2BE40864F26" modified="2025-10-08" version="1">MGALDRLSSISNQLTGGSAGGKAKLLEKHPDDVVVTAALRTPFTKGGKGGFKDTQASDLMAGALKSLLERSRIDPALVEDVAVGTVLAPGGGATEMRAAVLVAGFPTSTAAHTLNRQCSSGLQACVDIANRIRTGMIDIGIGAGVESMSTQYGPAAVSEFSELLESHPESANCKVGMGQLSEQMAQDRHISRASQDAFAAASYQKAAKAQEAGLFKDELAPQTVQFEDPKSGETKTITVDRDDGVRPGVTAESLGKIRASFAKDGSIHAGNASQISDGAAAVLLMRRSVAEKLGQPILGKYVAASIVGVPPLLMGVGPWKAIPKALELAQITKEDVDVFEINEAFASQCLWCANELGLPVEKINPLGGAIAFGHPLGCTGARQVSTLLYQLRRTNQKVGVTSMCVGTGMGMAAVWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI46</accession>
    <name>A0ABR3ZI46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the Golgi-associated retrograde protein (GARP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014812">
        <property type="entry name" value="Vps51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="319" mass="33854" checksum="AF540B0AE2081718" modified="2025-10-08" version="1">MSTIASPREPPMRRMPSSSQTPTSSSRPSLETSRRSLSSSPSRNPAASAAGGSAAAGAGTSTAGGAPGGAARRNRAALREYYNLKKTGGGNTPVLEVTEFDSSNGTDALHAGILSNSEVPPSEMDAPNFDPDAYVQKTLQESGLEDLLKIYTRVLTETRALDAEKKSLVYDNYSRLITATETIRKMRATMDPLNPMASTLDPAIAHIYNQAKTLRDAMRENVPPPSSDDDDKTSAAARARNQKLAAAVLQTPDRLRKLVAAGRTEEAEKAWERPRQLLEAWKEHGVGGDDVAACLADGAAALRGEPSPAGRSVQPAGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI79</accession>
    <name>A0ABR3ZI79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_002715</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="70" mass="7943" checksum="944B4FE424E9BEC5" modified="2025-10-08" version="1">MPVPFETLIPYGIMIAMFGISGAGLSKIRHMQNGGKRARRSIDQWDRSDNPLAPPGFDVNNPWRLEKRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI81</accession>
    <name>A0ABR3ZI81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial 54S ribosomal protein YmL35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MRPL35</name>
        <name evidence="2" type="ORF">Sste5346_002788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="526" mass="58602" checksum="7090230FB7CF58BD" modified="2025-10-08" version="1">MSRYTPAARPLVQCLRAGGHRSEQATLVLRPATQSPMQATTSAFSTSTRQSNTDTTTSSASPSTPPPPQRLEDLEGWQRDPNSVALPWAERELMRRGTPPIGSRRRRAALQMATAMTRAQAGNDTLADSAGGPIPFELMPYQCFQEARKVLQADREEKLCKIAVETAKIRKLEEVLATASSDPAKVSSRGGKGYIQKRLTSLRKHLDHLKVMADINDPLVKRRFEDGLGDMNKPVYRHLAEERWRGRPFRLIQQRIEQFHLAPDLLPPNQLHPSADVELFFRTYKVSHGAIVDSLISEVVPRLRIQVFDRGTRLVSIVVVDADVPDLENDGFSRRVHFMATNVPVGPAEPSVPLARLDSASQVVLPWLPAFAQKGSNPHRLAVFVLEQPAIDAELPDKNSSRLDTAALQKTFSSDPESAIANVTADGKPDVLAGRDNFNIRSFVDKHDLTVVGCTLFRTEWDAGTAGVMERLGVPGADVELKATRYNSLKPPRKARGWEAKHQGPKFRHLWKYTHRIATPKRKFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIH2</accession>
    <name>A0ABR3ZIH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SLM5</name>
        <name evidence="10" type="ORF">Sste5346_002219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="218"/>
            <end position="580"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="1"/>
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            <begin position="57"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
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            <dbReference type="ARBA" id="ARBA00022741"/>
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            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
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            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900498.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="588" mass="64690" checksum="8537A6E0FE06DA6A" modified="2025-10-08" version="1">MMRPRISPALRPAPLRASSTAPFSSTTSARTILTTPNPTTSSTQPQPRVPSTRRRQSLQFSCQLSQQSRLRSSQASSPSSETPRSVADFLQWTPTDAVPDVVVHGFVRSVRTMKKYSFVTLGDGSSLAGLQAVVPASLLEELSDTSAHLTNGAAVRLEGAWTPSPGTGQSHELHVTSFEVVGPSDAKTFPIQKKYQTSEFLRTLPHLRPRIPFNTTLLRFRSDVVASLNRFFAERQFVQTHPPLITSSDCEGAGEVFTVTGGPSSTSNFFRSPKYLTVSAQLHLEALAQAVGNVWTLSPTFRAETSDTPRHLNEFYMLEAEVSFVDRLDGVMDLVEDMLRHVAKENHGGRAYGELVAVAKSAKPSRPNKSNKEGKDDKDDVDSTPVVDIETRWSGILSAKPWPRITYAETLRILNEAPANTFEYPPAWETGLMTEHERYLARVIGGAEATPVFVTHYPRESKAFYMLPTATTGASEASQDTVDCFDLLVPEFCEIAGGSMREHRFSELVATMQARGMAVDAKGAARVNEAGEATVGNGLDWYVDLRRWGCPPHGGFGIGFDRFLCYLTGVPTIRDMVAFPRWYGRCDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKH5</accession>
    <name>A0ABR3ZKH5_9PEZI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Sste5346_002263</name>
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    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAL1900540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="395"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="820"/>
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        </source>
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        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1035" mass="111308" checksum="E1262ED221A5ECFE" modified="2025-10-08" version="1">MDEADDDLDEADELADELGVELGGTELPDEADELTDDDEPEGVELGGTDELPEAEDEMSLLHGSEEELAEELTLAEDETDKIDEAELLADDEPEEADDEADELPELAEADELTDEDDPDGVELGGTDELAEELIEDEISLLQGSEEELAEAEELMLTEDEADEEAEIELLADELPEELAETEELAEEADEEPEDVDDETEEADELAEDDGVELTEFEGLELAEEDGVELTDEGVELGGTEELSLIDEEMSLLQGSSEELAELVDETEEPDETDETEDTDEAELLIELAEDDGVELTEFEGVELAEDEGAELTDFEGVELIELTDEGVELGGTDELPLIEDEISLLQGSSEEELADAEELWLTDETDETEEADEMDEAELLTELADELAELTELAELAEDEPEEADELADEADEEGVELAEFEGVELTDDEGVELAECEEEGDELAEDEGVELGGTDELLSLIEEEMSLLQGSSEEELADETDETDETTEIELLTELADGKDDGDDDGDELGDDDGEEEGDEEGDELGLLLGDDTEGEDEGEDDGELEADDEGVLDGRDELGLGDGDEEGVELTLGDTEGLLLGELLGELLGEDKGDELGDELELKDSDEEISLLQGSSELLDSEAEDETDETDENEETLEAEDEGVLEGRDELGIGDGEDEGDELGELLGDELGEELGELLGDELGDEEGEELGLEISEEMSLLHGSSLLLDSEADEETEEIEEIEEALDEGVLDGREELGLGEGDEEGDELGELLGELLGELLGELLGELLGELLGELLGEELGEELGDELGELLGELLGSDELGLEISDEMSLLQGSSLLDSEEDEEVDDTLEEGVEETLDEGVDEAEDEGVLEGRDELGLGEGDDERDDEGDELGELLGELLGDELGEELGEELGDELGELLGELLGREELGLEISDEMSLLQGSSEELLALLSLALALTLLETLLALLLTLLLVELINDDDDSLLQGSSSAKMQLHAAVMEATSAEQLPVQSVGRSQDSLVGGCKKTSHHSQGSGLFLMSIMAWTHAVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLM7</accession>
    <name>A0ABR3ZLM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TTAGGG repeat binding factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TBF1</name>
        <name evidence="7" type="ORF">Sste5346_001991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013867">
        <property type="entry name" value="Telomere_rpt-bd_fac_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052833">
        <property type="entry name" value="Telomeric_DNA-bd_trans-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807:SF1">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08558">
        <property type="entry name" value="TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342774" evidence="5">
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            <begin position="17"/>
            <end position="1201"/>
        </location>
    </feature>
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        <location>
            <begin position="529"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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        </location>
    </feature>
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            <begin position="716"/>
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        </location>
    </feature>
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        <location>
            <begin position="910"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="1098"/>
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        <location>
            <begin position="341"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="507"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
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            <begin position="615"/>
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        <location>
            <begin position="917"/>
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        <location>
            <begin position="978"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1005"/>
            <end position="1014"/>
        </location>
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        <location>
            <begin position="1056"/>
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            <begin position="1098"/>
            <end position="1119"/>
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        <location>
            <begin position="1129"/>
            <end position="1144"/>
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        <location>
            <begin position="1145"/>
            <end position="1171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1201" mass="124965" checksum="6A5F429EFDC440CD" modified="2025-10-08" version="1">MGLPLLGNFAIQLVYALSENPGLGQADDGTATDSRRIYRLLRSAFHDTRKLFSEQAGILSTDELEIKEAGDQETIQMANMATIASSIFESDDDISLTDAHDNFLSSFLTDPEALDKDLADLFVNLKYCMLAAELVRLPDDEKRREFVERLFPVNLQEQLQNLHVDTPITDYEKVFLKDIVDVKEKMLEAVKTEESRQQLQNHFSLDGFRDELRDYLRANEDIVLRYADSHGIEMPGDDDANGDDSEMAADQAEPSIINGTDFTAMGNSIASMLSAAMASSDALAATAASQASAQQAAAPAATNGPTPMVIDSVNGVSDRSALEASPMAEGVSRLIQEAVQRSAARTSSQPPAASPQASTLGLLATPSIRTHTTAPPPNGIAAAPPAPTESMMDLTGLTKLIQDKLGQEAQEAQAPPASAPTLAPTPAYNMQQQTQSPVAQANAALSSMQNTFANNLAMYNRAPAFPYQQVQAPPPPPPQQQQVNTLNGGNPALPPHQSSPSAILYQQARQAAASKTQGHTRREGLHSTRRPWSPDEEQALMAGLDMVKGPHWSQILQLFGANGSLSDILKDRSQVQLKDKARNLKLFFLKANTEMPYYLKCVTGELKTRAPSQAARKEAEERAKATNKEEQARVQGIMTLAGGLQDNSNKMQNQNTAAPVTAHAPAHAPSYAPTHAPAHNVTAGHAPVVHHHNGMANGNVNVNNAVPINGAARPVAAAAPTGPPNGMQNGGATNGAVRTGAPTTLHNLAPNPPVSNLPPRIASATQLSPAVQQQLQQLQQQRQMQQTQLPPRQTTGTATTGTTIGTGAGAGATGVPQRTPVTAADVALAAARGGYSATAQALAAQQANGSAAGRPLLASGALSRASLGTTSASIKSVTADLTAGMTAAINNAINNAAIAARPTSTMLTSAQRLAAGRPSSISPSRSLPQQQQHRPAQSSPSPIRNLAPQSPAVAQEAAARPVQATASPARPSPAPTYAQPSPNVTAQPMRSPATLAGTPKASAHATPQPQSHPSTTVLAPAAAPTTAAPVVQATTTASTTAPAKALVAAPLPTPAAAPVTTQAPATTQPPAQAPAPAAPQQPEDRLWMLQQHIHTEAPRTTPAAAAAPANGAANAAMKPAPAPAPAVPTPAATAPTPTTTTPAPVAAPPATPANVPTPSPVPVVKAPPPNPQQQQQQQKQEQQEDASEESVLARLLASPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLP4</accession>
    <name>A0ABR3ZLP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Kinetochore-associated protein MTW1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_001764</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mis12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="305"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="40394" checksum="559B28DF7DE8D2AD" modified="2025-10-08" version="1">MASSATADTELLTEHFGYPPVSLLDDIINSVNILAERALNSVEQALLRQPPASLGFKPASFQRGRGEEKLSQDALEAAAEDAHRHEVENGTHQLETLLCASIDRNFDKFEIYAMRNIMVVKPEDRDWMRLAHYEGLDFEAATAEGNAADAGNGDAGEEDDASIAHLHRRLQASIKLGHLLDVEAQKNEAMLAKLRTLAVPRTPESTPSAASLAFLLDRGPLTESDAAQPLTTTTAFALSQLPALRQLSSELRQKAPGLAAAVALDDEEKEAGDNSGSSGRAGDSKSWRRERLEYIEGSTRKHLERARGLNLGRNGEMRGDASSSSQNNDGGSNMTVEPEALTNILNILRDNHGSKEAAAEDTSQPEDETMDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM53</accession>
    <name>A0ABR3ZM53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002192</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF114">
        <property type="entry name" value="ARYL-ALCOHOL OXIDASE VANILLYL-ALCOHOL OXIDASE (AFU_ORTHOLOGUE AFUA_3G09500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="81"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="575" mass="63799" checksum="9334C96F02DCEE1C" modified="2025-10-08" version="1">MTSAQPQNTYPDQEYEDAHLMTFSTPKVAIPSILPPDVSQETFSQAISEFAHAIGKDNVFIGEGLSHYVDPYDLSEDDATKRKLPSAAVCPSNVDQVRAVLAIATKHSIPLWTFSRGKNLGYGGPAPRINGSVALDLHKMNRIIEVNDEFSYAVVEPGVTWKDLIDYCNNNGKKVWPSTPSLSWGSVTGNTVDRGTGFGGNFCHFQNISGLEVLLGDGDVVRTGQFGIDGSPSAFLSKFTYGPSIEGLFLQSNLGVVTKLSIWLTPQPQAYMECTLTVPLFEDVEPLVDSLGRMRQTGLIPTCVWVLSRNEIISTLGKRHEFWSGEGAIPEWRLAEIGKQFGLSYWVARWAIYGPKRTVQAQFDDIQEILAREVPTGTVKGTLFVGKDGELLKNTDIPADNGRLMTGVSSMFSLPFIDWALPADGTGKGAHGDYAPIIPNSGKLVLEWLQASYKRYEEAGFEPATDFFMHERHILMVNMFAYNQRDHQQTTNVEKMFLGFHEDSAARGFGMYRSHVNFMDLIAQHSNFNNYAYTRFVEKIKDAVDPSGILSPGKSGIWPQKYRHLRETPAKNGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMD0</accession>
    <name>A0ABR3ZMD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF81">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="76"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="588" mass="62860" checksum="5237A29699B158DF" modified="2025-10-08" version="1">MQTLDHTEYSNHDRIEHSSSSVEHQRLLAEDDDDDNDSDLELDIEAELGHTPVDPSHTTTATSDDDWKPPPGFLWIQVAIMANVFLSGFDGTITASTYAVISSDFGAANAASWLTTSYLVTSTAFQPLYGRVSDLVGRRVCFLLSTAAFALGCAGCALAPSILVLNSMRALAGLGGGGLMTMATIVNSDMIPFRRRGMYQAMQNGVYGFGAICGASFGGSITDTIGWRWCFASQVPVSIVVFVLGMRVVKNPAHMLLSGVDGSFRRTWARIDVTGALLLVVGVSVQLVGLSLGGNELPWSSPWVWLCLVGSVVLLALFLAVEGRRERTTDADGRPTVAPIIPLRMLRGRLPLATQAANVCVGFAAYAYLFSLPLFFQVVLRDSATKAGARLAIPSLASPIGGLVAGVVMSRWGRLTTLVRVGASFMVLGNGLVASLGFEGVAAWKYLVYIFPANLGQGIVFPGLLFTSLATFEHNDHAVAASSVYLIRSLGMVWGVAITSAVLQTTLSLRLPQVLADAIKDTDELERVVDELRHSVSYLLDLPAGLQLKARHVYYEGLQYSFAASAVVALLAVVASLFINGKGLRSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMR7</accession>
    <name>A0ABR3ZMR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin cytoskeleton-regulatory complex protein SLA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">SLA1</name>
        <name evidence="18" type="ORF">Sste5346_001919</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SLA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11773">
        <property type="entry name" value="SH3_Sla1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11775">
        <property type="entry name" value="SH3_Sla1p_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.700">
        <property type="entry name" value="SLA1 homology domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056996">
        <property type="entry name" value="PH_SLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035800">
        <property type="entry name" value="Sla1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035821">
        <property type="entry name" value="Sla1_SH3_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF19">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN SLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24081">
        <property type="entry name" value="PH_SLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="11" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="17">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="17">
        <location>
            <begin position="399"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="128"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="462"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="663"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="760"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="914"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="988"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1160"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="477"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="507"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="807"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="867"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="942"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="988"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1017"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1163"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1187"/>
            <end position="1202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1901512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1235" mass="132856" checksum="AFE3E7C78771D6AA" modified="2025-10-08" version="1">MGFVGVYKALYDYVPQSEGELAITEGSLLYILDKDGGDGWWKAKKKAGDDDEDEPEGLIPENYVEEAQPVRHARALYDYIRQTDEELSFPEDAQLAIYDISDPDWILAGYENEYGFAPANYIDMDGTSAAPAEAEEEEPEAEAPPPALPSRQATFDDDDTPSPRLPPRGAPSEPSSPNANSAAAAALANVLAGRSAAQRPATPPPSLPDRPRYMSDDASEGEDPLSPPLPTRPQPQANFDDDQPSPSLPQRSHTNNYGGGSSSGRGGRNGGGYDEEEHASNTLSPGGFHLYNISEMVSVMGKRKKMPTTLGINLKTGVILIAPERSQDGPSQEWSAEKMTHYSREGKHVFMELVKPSKSVDFHAGAKDTAEEIVSALGELAGAVRAEGLREVILAGTGHELKKAVVLYDFMAQGDDEVTVATGDEVIVLDDQRSEEWCQVRRVKNGKEGVVPLSYVEVTGTITSDIPPQPVSSGYHSPAPSSPTTNSAPAISTQMATVGARSTVKQNRMDEERLTRDAVRAAVRDESRRANEVGNGVHPPERRSSLYATNINTGEQQQRKKENGNGSSSRSGKASTYKAPLKHDPLWPPTNRTEPDASKVRTWTDRTKSFSVDAQFLGLKDGKINLHKMNGVKIAVPVAKMSLEDLEYVEAVTGISLDEDKPLSSMKRKSQIQQQHDESQNSSGTKVGASIEPKKSDYDWFQFFLTCDVAVGLCERYAQAFVKDNMDESVLPDIDASNLRTLGLREGDIIKVMRYLDGKYSRGKKGGDDGGEGGLFSGPGGTLRNNTRRGRPTPSTQASDVVDAKAFSQQTSGGSDESNATNGNRVASPVSQAPTERIAPPPKQAPAATGAGGFDDDAWDVKPSRQPAPAAATPEPPVVQRAPEPAPPPPVAKQQTAALTGSLQELSLLTQPLPAEKLNPNPPPAITLPPQATPAVSLPTIQQQQQQQQQQQQQMPGASPAMFAGLAQQQTGIQTGIQGINGLQPQQTAAAFARARPMAPQYTQGQGGLLPPPPSRPLSAPQSAQPSAFSPPPLQPQMTGMVTGQVAPMGQSLNDITQARMQQQFQQQQQQFQQQMMAQQQQQQPQGMMPMMTGMPMQQQQPQPTGFGMPQQQFMPPQQNQFGQPVQMQPTGFNQFGMAPPPGATLNSMLPPALEPQRTAMPAPQPMQPQPTGPFTQGFGNHGMAPTPAPLMPQQTGPPPPVRFGVTEETKKLMPQATGRRANLSAATPDNPFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNS7</accession>
    <name>A0ABR3ZNS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pantothenate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="57048" checksum="5808999FE10E65D7" modified="2025-10-08" version="1">MSDVHKATKRLTPWQLFKEVFNWYPSEYPAAERKLLFKLDLSILVFACLCFFVKYLDQTNISNAYVSGLQEDFGLYGNQLNYLNVTYFTAYVVFQVPGLMLMSRPKLARWLLPTLEVLWGIATFATSRTTNVNQLYAIRFIIGMLEAPVFAGTHFILGSWYGGHELFKRAGTWFICNALGSMVSGYLQAAAYTNLSGVGGMEGWRWLFIIDGVFTIPVALLGYIIFPGVPDSPKPFHLTDADIVLAKQRLTRFKVRRPGPLGLDVFKRSLQRWHIWVFVFCYICMICSSYPLSYMNLWLKSEGYSVVQVNRLPTVTYAINIVASWLGTTLAAIYPSWIIYTVIETCCVFSTICMIIWNIPTGLKFFAWYLYGVAGCASPILYSAVNTIVRDDSEERALILGSMMTVGYSFNIWVPLLVFPTAGPNGAPRWKKGWPFILVFFVLLWAGFITSILLHRRDTKRNAVHAGTGPPIDGTDSERESEDVSEPVSSADGEVAIINQTVEAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPF9</accession>
    <name>A0ABR3ZPF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08192">
        <property type="entry name" value="MAR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF107">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="2">
        <location>
            <begin position="29"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="3">
        <location>
            <begin position="209"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="44495" checksum="27F5ABF26B696BF0" modified="2025-10-08" version="1">MAEHVERFNPAKELPIISYGLPYEDAIAQHLTTTLKRTRPYLLVSGSLSRDTDVVDRLTKRLKAAGAEVAAVTTGIRSHTLYEDLLPILAEFRSTKADSFVVVGGGSLVDGAKVMSYALANGVDSHESFESLAERSGTNGGPNIKHSEIPYMCATTTLSAGEYSTFGGATNERTHHKQLFYDPSENAGHRVIVIDPRLTLTAPPSVWLSTGMRAVDHCVETVCAKDPKPEATAAALQGIRQLIPALLRSKKDANDLDARLQAQLGAGQSMKGVVVYDVALGGSHGIGHQLGPQGVPHAETTCVLLPAVLKYNARVNKDQQKLVLDTLWDEPIVAETLVKQGKLDRETADLGDALDVIIRALDLPRKLSHYGIGRNKLDSIATISLSDWMVKTNPVPLDTKEKILEILEQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ70</accession>
    <name>A0ABR3ZQ70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001372</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF28">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="207"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="491"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="898"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="898"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="957" mass="104792" checksum="B58CC4C52C3CB4B2" modified="2025-10-08" version="1">MSRTPPRQRLDRLDHSSSEAEREQRPYKIRKTHGDTHGLHGLLHGDTHVDRDSRLGQLGQRGQHRKDIREAPAPAPSASAGEDRNRIPIPSSETSHTNEASSSLSNHNDDREGEGVPNNSGTTTPPKRTRDMDQKISCELCKTRKVKCDRAEPACSWCARHNRQCVYLKRQTPGSRTRINAELEAKVNRIDSLLRALGRRVEEHISQDHAADFERSRTAGPSTASGGQAGSSNGDGVSPSLGSPTAAGSIFRGGDDDNNSNPNATPNTTAGNPISNGNNPNQTPISLPPPVTSSSGISMIWQSGATDYDDDASTVAGGMNQYQQNQGQRYAQAPTFRTPKPPTAELPPHDMLYTLVDLFFKHCNTWCPILDRKTIFGTFFGATSLEEPDRVLLHAIVATTLRFSKDARLTPEARDYYHTTSSQVVRLYAMDHITVPALRALVIVSLDEFGTSSGPRAWNLLAMVAQNVRQLGLCDEVSVYLAPSAVDLEQQQQQQQALNDNSITNPSGPGPRPIHQSKPDSWIEDEGRRRLCWVVYLLDRYATVCAATTTSLSGPGSGFLIEDTAMHRFLPCSYDLFSKNVPVETRSSNAWSDMGTEFSGTPHNMPPPTPLSETASSMANKAEHLGSFSYHCKLLRILSRIHDFLREPVDINSSADMARWRNTYQALDATLDGWLRGLPSEFSKISALCHSDPASRVANWFMLHSAYVTAVVRLHAPAAYPTARSTLFMPSQYAVQRCLAAVHSLADIARDLREANGLDLLGPPFAFSLWVAARVLLVHASVQEAPGHSGGPQPLDGHSRIDFFIETLRHVGRHWAVANHYAATLARVAQRGRQGEITFSNMRRSAYDLLALTSTSRQSGAEPMSTQVTSLCELDNIDVFSFFVYPRMVEDDMMPQPQQHHQMAPSMAPSVSSMGNTSNPGSNMGGVGGGMNSVLRTPMPPSMSMLPGSPHRGSSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ82</accession>
    <name>A0ABR3ZQ82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524:SF1">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="330"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="467" mass="48992" checksum="806C7A475FD21E74" modified="2025-10-08" version="1">MAPYDSDSSDDEDAGPQNYTETNVLLGYADPEDQDADDDAPDNKETVSRLGGRPDWIVAVQAPPSAGLARCLVCKALLVLLLQLNGELPERFPGHERRLYVLACRNKSCRRKPGSVRVIRGVRVDAAVAEAAAAEKAKKETAEATRASKPVGTAPGLGNSLFGVANPFSAGGGSTSSANPFSLGGASSSATGGASNPFSLGGAASSTPASKAAPAKPQPSSSSEKTQKATDEAAKELPKTFAETLSINNDKPEPAAAAAPAEPWPPADSWPAAYPVSWIADAEYETLDPTPAPIPGVVTEAMEVEGESSAGGSGSGSGKEDKFVFESDMDAAFQKFADRVAQNPDQVIRYEFNGLPLFYNKDDTVAGIWAQLQTGGGSISTVLASTSGRLPPCPNCRARRVFEVQLMPHAIDLLEADELGLEGMDWGTVLVAVCEKDCQAKTTPAGEASYLEEWVGVQWEDLESSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQG5</accession>
    <name>A0ABR3ZQG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L28</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL28</name>
        <name evidence="7" type="ORF">Sste5346_001392</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="72"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="149" mass="16963" checksum="343193C1BB3BE4C1" modified="2025-10-08" version="1">MPTRFSKTRKHRGHVSAGKGRVGKHRKHPGGRGMAGGMHHHRTNIDKYHPGYFGKVGMRRFHLLRNHQWNPVINLDKLWSLVPEETRTKYLSGEKKDTAPVIDLLPFGYSKLLGKGRLPEIPFVVRARYVSKLAERKLKEAGAVIELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRM3</accession>
    <name>A0ABR3ZRM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein HMF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="13416" checksum="E9783D8F2D52CCD3" modified="2025-10-08" version="1">MSQEVIFTEEAAFPAGPYSQAIKTPFAIFCSGQIPSDKTGALIEGTIQDKTAQCIKNLEAVLKAADSSLAKVVKVNIFLADMGFFADMNGEYAKWFTHKPARSCVAVKTLPKNVDIEIECIALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRN9</accession>
    <name>A0ABR3ZRN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts with hulA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="4">
        <location>
            <begin position="184"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="442"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="485"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="574"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="485"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="745" mass="80652" checksum="41A1E325292CFB55" modified="2025-10-08" version="1">MPFNPFTSVTGRNALTLFDIRLENDFIVFRGNEHEASGQLLKGVLAICVPSPIKIEDIHMRLTGTQRLVWTDPKVTPSGLASTKVDRTHNILNHQWAPFWGTPGKSAVLEKGNYEFPFEYMLTGDTCESVEGLHEASITYKLKATIARGKLAYDLHAYKHVRIVRTLESSALEFLHAMSVENIWPNKVEYSIVVPQKAVVFGSHIPLESRFTPLLKGLELGDITVRLIEIHEFVSSPPPGTSNYNPAMREFKHEKLVQSWTVNVNREEHWQEMIEDTGQEGWVVNTSLDLPRKLGKCIQDVNVHGIKVRHKLKMVVALKNPDGHVSELRATLPLTIFISPNIPLDEQGNLTAPTGSATANATGLSTIAPPGYGEHVLDQLYDEVDVHNLQTPAPMSAVQSPMYGMSRAGSSENLASMNNPSIPVHPGALTSRLQDVSARELAIRRNRSSTILTPPGSSSDMTTPFTPMHLPHSFMQRSHSHAADLGNLANSHNSHNSHGAAHASGTASGTHSHPQSEAASRRNSGESRHSVGNNSEHSEHSDPEHVDFADLQELCKVPSYATAIKTTRVNKITVGGDSQLPDYRTAASRPAVSRTSSTQSLPGNLSSSNNNSSSGSALGSGLTSEPLSLIAEAPQEAAAALEDVTSAPASRASSNGNNSGASDGGEGLTIARPQRLHHRSRTAGYQPEQTSTSPGTGSGSGSSHRRRPLSSSVSFLHSRHNQPPSGDNDERSWLHLLQARGRVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS26</accession>
    <name>A0ABR3ZS26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06168">
        <property type="entry name" value="LSMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034110">
        <property type="entry name" value="LSMD1_Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF5">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="129" mass="14240" checksum="CDB9404B114CD9F0" modified="2025-10-08" version="1">MDTPAPAVAGATSSANAAAIREESRAYLQTLLNKNLLVHTTDGRMFRGEFKCTDPDRNIVLAHATEYRQPTARQRAQYAAQQAAAGQSSRAVMNMTSRYLGLIVTPGHHIVKIEVEEFASQMKRPPRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSD7</accession>
    <name>A0ABR3ZSD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NADPH:adrenodoxin oxidoreductase, mitochondrial</fullName>
            <ecNumber evidence="8">1.18.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARH1</name>
        <name evidence="10" type="ORF">Sste5346_000928</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 reduced [adrenodoxin] + NADP(+) + H(+) = 2 oxidized [adrenodoxin] + NADPH</text>
            <dbReference type="Rhea" id="RHEA:42312"/>
            <dbReference type="Rhea" id="RHEA-COMP:9998"/>
            <dbReference type="Rhea" id="RHEA-COMP:9999"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.6" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055275">
        <property type="entry name" value="Ferredox_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021163">
        <property type="entry name" value="Ferredox_Rdtase_adrenod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000362">
        <property type="entry name" value="FNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="9">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="489" mass="53132" checksum="63B44FF2A39DB2FF" modified="2025-10-08" version="1">MAVIGSGPAGFYTAYRVMAKTAARVDMYEALPVPFGLVRFGVAPDHPEVKNCQEKFEEVAQSPDFRFVGNVAVGDGSAATNSISSHNPNGGHVPLQTLARHYDAIVFAYGASKDRKLGVPGEKLRGVYAARDFVGWYNGLPSGEDNLGERIVADLVRADTDTAVVIGQGNVALDVARMLLEHVDVLRKTDMSEEALEALSKSRVNRVHVVGRRGPMQAAFTIKEVRELMKLPDVGLHPFDAATLLPPKLKDLPRAQRRLMEVVAKGSVTPLEQAQKSWSLDFCLAPNKFAAADGSEQGRVATATFEKTHLSSPFDANAQAEHTGELVDVPTQLVFRSIGYRSQPLAGFDDLGIPFDERRGMILNDGLGRVLRDVRSQDASMTTEPYPGFYCAGWVKRGPTGVIASTMEDAFTTADAIVNDWQAKAPFLTVGEEGGGWDGVKGEVDMIGARVVSWSDWQQIDKVELDKGKELDKPRNKFTQTADMLAVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFX0</accession>
    <name>A0ABR3YFX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HTA1</name>
        <name evidence="17" type="ORF">Sste5346_010467</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000155">
        <property type="protein sequence ID" value="KAL1887043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="13"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="16">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1887043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="134" mass="14154" checksum="FE0F3098B915AF18" modified="2025-10-08" version="1">MTGGGKSGGKASGSKNSQTRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTGKAGKNASQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGL2</accession>
    <name>A0ABR3YGL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="422" mass="47032" checksum="8ABDA90740E25144" modified="2025-10-08" version="1">MVTKKEFLERWTGDIEQEFTSTAGDPVSWEWAPDHPKAWSSARAIIDLVQETMSTPAFSSDEDLLAVGVGKDIHIYNVATQDRLAVLTGHYGVVENVRFSPTTYDGDYRYILASHSGVTLDDESEAILWKLDGNGQLSSKPQRLEGQLGLWGSSSFTPDGKMLIFISNNESTQFDDQDGVTREKDSLPCINLWSIEERTVQHRLLGHTDQIQSVTVSPDGKHHASASWDGTGRIWDAATGACIHVLGPFATTETTVGQMWSTAFSPNGKHVAISQESPWGLVHVCEVSTGKKLSSAKFHVWTRSLAWSPDGSLLACGADPGTVAIWDPLTDEEKTRWALKFDDYGMGTMARPRAVKFLGQDKIVFQLNEGTVWIYDWEKKQKYRFARGPEDEQDKFLQAKMVCTDKLLAVPDTKGSLRLWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHI6</accession>
    <name>A0ABR3YHI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010353</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000135">
        <property type="protein sequence ID" value="KAL1887216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF55">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="56722" checksum="70C1CBA3AA90A723" modified="2025-10-08" version="1">MTVVSSLSPYVTSNFGEHSLLPVISIVSSIVTGVMQLPISRVIDLYGRPQGLLAMVTLDVSGLVVMATCTNVRAYAAAQVLYYVGADGVIYIIRVFAMDRVAVRSRSMVYGASLYTYFVSPFVGPTLAQAYYKAGIWRWGFGSLAIIIPGVAFTLVFLFLWYEKRHPQPVRPGIKTQPVRPVHGSPFKAICFHLLDLDAVMGVLLACFGIALVLLPLSLTTNRVQEWKSGSTIAMLVMGVVCLIALIIYERLITTRHFVDFSLLRDRTAWGACLVMFGQTLSLYLWWSYYTSFLQVVHYRSIRDAGYILNTHQVGSAFFSVLTGFLLRYTRRFRSVNLVGVAITTLGTGLMVHYSYPDSNFGGVVGCHILIAISSGILTASEVAAVLNGRDDGSVSMRVALLFVFSYIGAAIGSTIATPVWRTRFPHLLAKYLPAELQDQANTIFGSLTVQLSYARGTPSREAIIRAMCETWRYLIIASIATLALAWVGCALLREGEGRLETSDEEEKQTRENSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL5</accession>
    <name>A0ABR3YHL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009989</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="50"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="59827" checksum="D2BAD30F976AEFBD" modified="2025-10-08" version="1">MPFQRRNSLSPSPLARRLLDDDAEKEIHQLPPPPKKNGPVSWSSLPRKGQLAILFLCRFVDFLQVASLQAYVFYQLKSMATGDKSDAAVSTQAGLLQGCFTGAQVLTAILWGKAADAPWCGRKLVLIIGLAGTAVSCIGYGYATTFAWAAFWRVVGGGINGTVGIIRTMISEIIVDKKYQSRAFLILPMSFNLANMIGPVMGGFLADAPTSLPGLFGEGAIFGFDWIREYPYALPSVLNAMALAVTAIVVFFFLEETSKERRGKTDIGLHIAFRIRQIIRQSPSTEGYAPVQMAEPASLSVEPVALQPMSPTPSQKPSRSRTTLPFSRIWTRNVVLTLVTIALYDFHLGAFANVWALFLSTPRVENGSASAHGLGMPASRVGVATSFLGVLGMLLQLTLYPPISARLGTLRSFRWFLVGFPLAYFAAPLLAVLPSTTLPPLPAGGFLIWASIIIVLLLQVTARTFTLPASIILLNNCSPHPSVLGTVHGLGQSVSAGFRTVGPVVGGWWYGWGLEHGVVAAGWYGVAAMSVVGCVSALWIYEGSGHEIVLEGDDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHX9</accession>
    <name>A0ABR3YHX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Bifunctional hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase fox2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FOX2_2</name>
        <name evidence="11" type="ORF">Sste5346_010134</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05353">
        <property type="entry name" value="hydroxyacyl-CoA-like_DH_SDR_c-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="10">
        <location>
            <begin position="318"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="911" mass="98101" checksum="97F5DA20D5D00079" modified="2025-10-08" version="1">MAEQLRFDDQVVVVTGAGGGLGKDYALFFASRGAKVVVNDIGVLVSGSGSASSRPADDVVNQIKKAGGEAVANYDSVEVGEKIIETAISKYGRIDVLVNNAGILRELPFSKTTDKDWDDHIRVHVSGSFKCARAAWPHFRKQKYGRVINTSSAAGIYGAGNLAAYSAAKTAIVGFTETLAKEGIKYNILSNAVSPAAASRMNETLGLDKEIMSLLSPAWVTPLVAFLAHKSNETETGYVYEVGGAHISKMRWQRADGLLLKCDETYTPGALLKNWKKIGDFSKDAQYPNGPNDFMTLLEDSIQMGPSERGEEVSFKGRVALITGGGAGIGRAYCLAFAKYGAAIVVNDLANPDDVVNEIKAMGGKAVGVKASAEDGDTVVKAAIDAFGRIDIVINNAGILRDKAFANMDDKMWDAVMNVHARGTFKVTKAAWPYFVKQNYGRVVNTTSTSGIYGNFGQANYSAAKCAILGLSMAAAVEGQKHNIYINTIAPNAGTAMTRTILPEEMVQAFKPDYIAPLVLALCSDKVPENPTGLLYEVGSGWAGRTRFERSFGVAYPRDKALTPEDVAKTWDQIVDFDNGKADHPTKAEASLSWLKAEQKIKAKSDAAPSGESNEYLRAIEAAKNAKPIPSEYTFAERDSMLYNLGVGAKRTDLKYVFEGADDFQVLPTFGVIPPFDAEMPYSFDDIVPNFSPMMLLHGEQYLEVRKYPVPTSGRLLSYGKLLEVVDKGKSAIVRNGITTVNAETGEELFYNEVSVFLRGCGGFGGQSKVQDRGAATAANNVPTDRAPDAVVEEKTTEEQAALYRLSGDYNPLHVDPAFAKMGGFKVPILHGLCFFGFAGKAVYETFGPFRNIKVRFAGSVLPGQTLVTEMWKDKANPGKIIFQTKVKETGKLAIGGAAAELVSSAEKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHY3</accession>
    <name>A0ABR3YHY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Family of serine hydrolases 3</fullName>
            <ecNumber evidence="4">1.5.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FSH3</name>
        <name evidence="4" type="ORF">Sste5346_009878</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="278" mass="30653" checksum="D6A39A8EE7F2B7A5" modified="2025-10-08" version="1">MASQTQTHPHPQAANRPPKPPAVPKRSVKILMLHGYTQSGALFRAKTRALEKMLQKSLAPFHLAPTMIYPTGPNRLRPRDIPGYQPPEDGSVENDDEDTSDSWAWWRRDDATGEYRFLKEGMTRLAETIKEAGGVDGVLGFSQGGAASGIVAAALEEGRQPPSGEEWSWVKALRAANGHKPLKFAVIYSGFFAPPENLDWLYGPKIKTPTLHFIGGLDTVVDETRTQALIDRCLEPIALTHPGGHYVPINKEWVMPLVSFVKTQAEKNSEEAVAEPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI73</accession>
    <name>A0ABR3YI73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Haloacid dehalogenase, type II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF3">
        <property type="entry name" value="HALOACID DEHALOGENASE, TYPE II (AFU_ORTHOLOGUE AFUA_2G07750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28195" checksum="B2B6033C6FE7DAF8" modified="2025-10-08" version="1">MAATKPIKAVFLDFMGTCLDWHSSVVRALPSSLPEETRSALALEWRQAFFDDIKSRPPGEAPENIDVVHERLLRRLLANEAHTSVATAIYTAGTETTIKAAVQAWHQMTAWPDVFAGLEKLRQLSPGGIEVFVLANGTTRLQLDLVRSSGLHPVIDMLFSSQLIGVAKPTPDIYKKALDLVGISRDHPEQAVMVAAHAYDLRAAKAVGLRTVYIRRWTDDQDELDDDLLVSENDGHVLDDFSGLAEEIQKLQTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI75</accession>
    <name>A0ABR3YI75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF122">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33831" checksum="401F028C9BE46777" modified="2025-10-08" version="1">MDNVVLPETDFTQVIHRDTYPAIEPSRPELSQEGRTVVVAGGGTNIGKAIATSFGQAKAATVIIVGRRQAVLDEAAKALEATASKGGSATKYVGKAVDLTNDAAVDTFWDGLASDGVHVDVLVQCSGIFGQPKPLIELGLEGINKMMASNFKGPVHNALRFGNQADKEREKFFVYVSTNAINYSDHNWLAMRPDYILSKNTATYAFSLLADGVKADNLQILSYHPGMIYTDAWPPLGFTKDMLPFDEIELPGNFAVWAASKEARFLHGRYVYATWDVDELASAEEKSCLDTDHNYLRVGVVGLTDGGHRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ17</accession>
    <name>A0ABR3YJ17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7556" checksum="4299A50B5D265873" modified="2025-10-08" version="1">MFFYGSTSLVFVIVMWFVIPETKNRSYVELDEMFELKVPTRQFATYETSVDRAKKAAAGLPVTQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ44</accession>
    <name>A0ABR3YJ44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial 54S ribosomal protein YmL19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MRPL19</name>
        <name evidence="7" type="ORF">Sste5346_009717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000098">
        <property type="protein sequence ID" value="KAL1888179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_uL11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="5">
        <location>
            <begin position="76"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="155" mass="16592" checksum="1EC694206B05F831" modified="2025-10-08" version="1">MSKRAAGPVDQMVKLIVGAGQASPSPPVGPALGSKGIKSMDFCKEFNARTAHLTPGTPLPVRVIVRPDRTFHFDVRTPQTSWLLLNTAEVPEGKGGKRRGAQKPGTETVGTVSLKHVYEIAKIKQSEQRLSGLSLESLCRSIIYQAKSMGVSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKK1</accession>
    <name>A0ABR3YKK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000095">
        <property type="protein sequence ID" value="KAL1888311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="103" mass="10849" checksum="9D6FF36A4BF3A22D" modified="2025-10-08" version="1">MSIRNDETAMPSPPSSPSLVPCDPFAPAMPSHDHDDDCFHLNLPSSPASPIVPHPRFILPSNGSEGIRSVPLPGVRCPKCAKDGKEVWVIPGRACGYCGTACG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKY4</accession>
    <name>A0ABR3YKY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1889011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="255" mass="28124" checksum="27B74F33097DE153" modified="2025-10-08" version="1">MTQLPEQCCTLPPFTSDYIPTGTYFTIPVPENNQPDLRVYNTGPTDAKTVLVCVYDIFSLHQNTLQGVDHLAAASGYRVVLPDLFRGESWPVDNMPPKEGRAALTAWVQARGNWEKQVRPALVAVVNKVKEDGAVKIGAYGFCFGAKKLIQSQPDHLFDSIGLIHPSFFVPEDGAQVRVPALLVPSSGEDQTIMDAVWAGIQRQGGVVAEKSVRQDFLDVHHGFAAARSNWADERLAGRARDCHALMMKFFKDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL50</accession>
    <name>A0ABR3YL50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclohexanone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="64138" checksum="6999FE434D27E41C" modified="2025-10-08" version="1">MGSVANGIITETDVVVIGAGFSGLYMVHSLRKFGFNVRAFEKAPDVGGTWYWNRYPGARCDSESLTYCYTFDEQLFQDWVWSERYPAGPEVLKYLRHVADRFDLRQHFQFETAVQSATYDEVARRWTITASTGEVVSTQFFISAVGNLSVPATPAVKGIESFQGQWLHTGRWPLQPIDFTGKRVAVIGTGSSGVQVTQEIAKTAAHLTVFQRTPTFTIPLRNMPLDPDYQRLWKSNARELIKKTRYSDGGLPFFASSTPLKGQDPEVVEQGLEAAWGVGGFKFLFGTFCDVGSDHESNAIVADFARRKIASIVKDAEKLRVLTPTGYPLGAKRIPLDTGYFQVYNQDNVHIVDLKENPIKEMTSGGLIAGETEHAFDLVIFATGFDAITGPLMQMDITGRGGQKLKDTWADGPYGYLGVGVPGFPNLLTLGGPGGVGVISNVPPTAEQAVEFAAECVAYLRDHNIDEIEATTEAADLWCEHVHAEAFKTMYPYAPSSWHDGSNLGKKARPFPAYTPGFSKFRRICDNIAAEGYTSFKLHHKGEAGSKANYKAHDPEWYTKVVQAPSSAELASWLEKSPMWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL80</accession>
    <name>A0ABR3YL80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin-related GTPase protein</fullName>
            <ecNumber evidence="7">3.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DNM1</name>
        <name evidence="7" type="ORF">Sste5346_009434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF235">
        <property type="entry name" value="DYNAMIN-RELATED PROTEIN DNM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="27"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="741"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="543"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="672"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="543"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="828" mass="90736" checksum="3467215962E1DE93" modified="2025-10-08" version="1">MAALGDELLTTVNKLQDLVFNTIGNDSLDLPQIVVVGSQSAGKSSVLENIVGRDFLPRGSGIVTRRPLILQLINVPEDEEDAAANAAATKARGYVDPNATRRNEWAEFHHLPNRRFNDFQDVKREIENETSRVAGNNKGITRQPINLKIYSPDVLNLTLVDLPGLTKVPIGDQPADIEKQTRNLISEYIAKPNSIILSVSPANVDIVNSEALKLARHVDPLGRRTIGVLTKVDLMDHGTNALDILSGRVYPLKLGWIGVVNRSQQDIQGNKPMDDALKAEADFFKHHPAYRNISTRCGTPYLAKTLNSTLMSHIRDRLPDIKARLNTLMGQTQQELASYGDMHFSGKEHRGSLILQLMTRFATSFISSIDGTSTEISTKELCGGARVYYIFNSVFGSSLESIDPTSNLSALDIRTAIRNSTGPRPSLFVPEMAFDLLVKPQIKLLEIPSQRCVELVYEELIKICHTCGSTELSRFPRLQAKLIETVSDLLRERLGPASNYVESLISIQRAYINTNHPNFLGAAAAMSHVVNEKQERERKRLIQEERERRERRRLKEIGAANGTGANGAAGAAGTETPEEVDEDNLSVAGGTGATSTALRKTAKGGRSSSMARENGRTASPTRFNQPAINNAKDSFLNYFFGKDGSAMGGGLGGSGPSGHHHNANIGRHVSQASEPTFSQSMRRPDDRPLRSPIGAGSDDYSRVGQPSAHPGALGAGGSMDLFGANGTGGEPALTDREAMETELIRALISSYFNIVRESIADQVPKAIMHLLVNHCKDVVQNRLVSELYKEMLFEELLYEDDGVKKEREKCERLLETYKEAAKIIGEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLL4</accession>
    <name>A0ABR3YLL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF135">
        <property type="entry name" value="ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="50"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="503"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="721"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="721"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="780" mass="85192" checksum="AA8621C3B645F31B" modified="2025-10-08" version="1">MTSMTSDSVSAIQVSCKQTRFQIESPNYRELDVEGLNIAVSAAPPPGTTLKAKGKAASRNTSLEILSDATLRLKAGQRYALIGRNGTGKSTLIRAIAEKLIPGIPEEARISILQQTNDNGEGADAKANRRTVLEEVIERATAKDELEQEIQTLSKGIDASTADDDTNDAYAALRALRKLRHDRLQKRLFVLDKNARLRSGARGMQARKALTALEKTVAEATAAWQQDDTEIAADALQAETQEAADLLAELQIQTEPARLAHIEARAKSILTGLGFSEAMAATKAVGDLSGGWRMRTALAAALLSDADILLLDEPTNFLDMLGIVWLQKFLLAGSEGSGTDDSTAGGEPVRPPPTLVLVSHDRDFVSSATDHLILLQDKGLAYYTGDLPSYEAAQAESRKHLHKIKDAQDRQRAHLQETIQRNMREGKKNNDDTRIRQAKMRQKKLDDRWGLETNAKGHRFKLNRDMPGFHLTKRDAIEAPTEARAMHIVLPEPPDLRFPGALLSLENVCFRYGVIKRNQEPPPWTLDMVNLNVHMGDRIGIVGLNGAGKSTLIRLLVGEDSISAGAGGQARIKPTKGTVTMHPRLRLAYYAQDAVDAIRALDLNNQDEAPLTALSLLTRDVAGQLTEGDLRALLGELGLPGRLASDTPLRRLSGGQLVRCALARLLWQRPQCLVLDEVTTHLDYETSTALRQALRTWPGAVVLVSHDRWFMRGAIEAEVDDVAGSGSDDDSSDGDEGVEDGPSGRKLVYRLRAGKLTLLDGGVQQFEDLLEKRVKKLLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLS8</accession>
    <name>A0ABR3YLS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ring-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000094">
        <property type="protein sequence ID" value="KAL1888334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="48882" checksum="3CF13675AC3ADDCB" modified="2025-10-08" version="1">MLDYFSTKKSRKPKPESASPSATSNQQKEQPPAKPPRPSSTSNRNSPVEDVPVLDRDEQSFLENLTHNWGTSDNDDDYVNDDGTGERPPLPPRIKTPDLTWDSDSESFVRSERLMAVDNDVLKPTSSKDKSGSGGVSGVGRRLSTFFSSKKGKGKDRPHPAHLTVPGKVDVDADAASSNSQLAAVVTPDEEDRERDDLARVLDNLDLGKDPSDKADLKGKDKDKSQSKASKFAVSLSAESTELVRRFVLVLKDLVNGVPTAGNDLKSLLDDRDGALARGFDRLPSSMRKLVSQLPSKLTSSLAPELLAAAAASQGVKYEEEKEGVTAKGAAKTMLLPLLTKPNAIVKMLKAIMNALKLRWPAFIGTSAIWSVALFLLLFVLWYCHKRGREVRLEKEATDAGEGPSNADELPDGADADAREPPIVIKEVSPKDEATTASGMPRPPIGPDAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMD6</accession>
    <name>A0ABR3YMD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="312" mass="34994" checksum="78919085F14EF0BC" modified="2025-10-08" version="1">MGSFNRFADLPAELRITIWRLSRQPRVVEVWYDADADCCRTTARPPALLHVNKESRAEALHKNWYRRCFRTSSYPQDHYIYFSPALDVLYLPRHGLMGYDDTARDFTVHVRDTAEHVRALAIDHVRTDTIRPWEPYNKLMLLLSFPHVQEAMLVVGSSQSSGSSGSSSPSSPSPGLAGQPYDRRVFRRRSQESIESAESVNTSSSLSSSSPSSSPPSKGVVVLVDPQGDSSAIMEVINNVIESFSREIEAVAAASDNNAVENDDNVSPLLKDDNCSPGRTRPHLPCLIPKAIAYHRQQRRHQRQKHRRAICA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMU1</accession>
    <name>A0ABR3YMU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hsp70 chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SSA2</name>
        <name evidence="3" type="ORF">Sste5346_009070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="239" mass="26081" checksum="B8A5377C4FD4AFAC" modified="2025-10-08" version="1" fragment="single">MAPAVGIDLGTTYSCVGIYRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFADAEVQADMKHFPFKVVDRAGKPVIEVEFKGETKQFTPEEISSMVLIKMRETAESYLGGTVNNAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKVEGERNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP59</accession>
    <name>A0ABR3YP59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PA14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008784</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018871">
        <property type="entry name" value="GLEYA_adhesin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10528">
        <property type="entry name" value="GLEYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854065" description="PA14 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="3">
        <location>
            <begin position="267"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="442" mass="46132" checksum="B3588316D930A2E4" modified="2025-10-08" version="1">MLHYNGLVKVILGLLPLTALPVHAGPCRPGKDAFCITHSDVLSSLKIDNTATAFCLNVLSISTATVESTVSVTPSASIDVVSSTFTASTVTSTFVSEDLQSSEATVTSTEVSFSTSTTTLTTSTVTYSCLDSAFTAKVVSPVQSALSQPSFPDKRSQPSSVSGPDAPAGLPDDWTPEAITAICSCLSLPTPTKTNVVTISLEPSIEVATSIVTYTPRATVTSSFVSVSTSTYTSVAVSVSVVIETEYATATTIATNGAAAYRRYFSPYDANLEDAGFTSDDFSPLNPSRPAVLSSGYLASLTFSNWPYGGTDLYLDDGAEFDASQAALLFQGFFVARQSGTYYLSTSGDYIDNYGYLWTGDVSYSTWSDSNAAFKASRTGDGYYGGSTSLSLNEGDAIPIAWLFANGGGAAQSYFVVTSPDGTSTTDTTGFLVPACSANTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA5</accession>
    <name>A0ABR3YPA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008696</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047013460" description="Chitin-binding type-1 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="49"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="310" mass="30684" checksum="BD79181135EC0C62" modified="2025-10-08" version="1">MRRHFTFLLAISASIGTAVSAHDIRDAVGDVASTSTSAAAVPTLVTSTDGTCGNGITCEGSTAGKCCSAHGYCGDGDAYCGAGCNSVFGSCNAGTGSGGSGSSPPAPAPTSVVWLTETTTISRTDVATRIVTSTSVSVTVSTSFVTSTATVTSGVKATQTATVTSTAVVTRTSTLVSISTLTTTTAVASTVVSTVLRTSVTIVTSTATVTATVAGNQPPAPTTGPGRPTGSPNPVPTVTTTVIVFGPGGNDGSSATLWFPQPTRGRNPPAATPSPILKGAVSDCTKYYKVQAGDTCDTVADKEDVPLVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQC0</accession>
    <name>A0ABR3YQC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="74"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="409" mass="43562" checksum="29C77CFB66716DD2" modified="2025-10-08" version="1">MPTSTVVQVADLSTGLVTDFSTTLGHALVEQQAQLLDGTLEARSSQNAQEDSLDLFPSLPKDQLAVVTPILGPKLNLKLLTIPVIRPRPGEVTVKIEWTGICGSDVMFSLGPQPGFPSEFHIGGHEGIGRVVASHDPSFVGLPVAARYLCNTCRACHHCREGVPESCSKQENFARTLAGTFQEYVTAPWDSFMPVPDWVLGEPDIVSPHLYTAALCSGAAALKAVKNAAVRPGDVVVVLGVAGGIGHLTGLLAKSAMHAKVIGVDMASKRDILDHGACDIFVPIADSGPGSPKDWDAFQREIADAVQWLRPRGSAVRKADSVIVTASTETAFVNLCDYVCDGGSIIKITGSLMGDWEETYEVMDHIRAGTIKPVTQVVTLDEVPDAMAKIHEDNHTGKLVVRVGGDVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRV9</accession>
    <name>A0ABR3YRV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypoxanthine-guanine phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HPT1</name>
        <name evidence="3" type="ORF">Sste5346_007869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="210" mass="23197" checksum="DD0EA537CEFA892B" modified="2025-10-08" version="1">MVQKLYVTYNEIHKLCQEAAPTILDKFQPQLMIAIGGGGYVPARILRSFLKKPGSPNIPIQAIGLSLYESLSTDAAAVEEEPGTKVTRTQWLDLSSLGEMSNLVGKNILIVDEVDDTRTTLEYAVKELEKDVELARQKIGADAAPTNFSVFVLHNKNKTKKGTLPADMMDEGRYMAARTVGDEWICYPWEATDIEAHDEAARQALANGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRZ6</accession>
    <name>A0ABR3YRZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF30">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="325" mass="36407" checksum="61A1F3C79D947ACF" modified="2025-10-08" version="1">MPTPGRTTVASKACDACRTRKVKCDLTPGVGDGERCRRCSRLDLACTFDRPSGLRGPRRRVTGASVINVKVRRPITAVTPTISITNTLTPDHVDTPSSTSQHIYPTDGLCARPLVRLIVEDYLERVYPLVPVVHRPSFCAALAADHDIDNPVFASLLLAICAVTVGLLPSRYESCYCTWSSPGPPLRFTSREAMMNYCYDGVLRRRGPRYFDEIDFAKLAISYLLSITFFQIGDQNRARMMEVEAMQLGRLLQVHKIQEYAGLSCIEAQLRRKGFWLLFYAYVHGELQNFRKERLCFLDAGQLAALDLEALLPLDIDDEQIVADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSC7</accession>
    <name>A0ABR3YSC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ARF1</name>
        <name evidence="13" type="ORF">Sste5346_007724</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 12" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="184" mass="20890" checksum="C09D35BC48ABD38E" modified="2025-10-08" version="1">MGLNFSRIFASFLGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYGNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIIEAREELQRMLNEDELRNAVLLIFANKQDLPNAMNAAEITDKLGLHSMRQRQWFIQSTCATSGDGLYEGLDWLSGALKKSQASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSN8</accession>
    <name>A0ABR3YSN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="24340" checksum="E406995FC75B1D2B" modified="2025-10-08" version="1">MDISQLTMPSRRQPPKSSAYVDPDETISATSDDGRTIVKDEKPLIAPAPAKKCAIMYIIDDDDDDDAAVSDIVVHYVKTARGSTAAKPILLDNNDVEDKVAAAPVPRVYHVRPRIKQEPVDDVPVVKIKKEFDPVADAKLSNALNGAQVNSFLSIPDNTQPSQDEPLLSFPPPTKDKAVVPSCESRFTALGDNWLDELYHETAIDNQAPPPAAASKTLLWWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTJ3</accession>
    <name>A0ABR3YTJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="9">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MAK5</name>
        <name evidence="14" type="ORF">Sste5346_007447</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17946">
        <property type="entry name" value="DEADc_DDX24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="234"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="265"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="533"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="92"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="672"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="234"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="141"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1891698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="839" mass="91916" checksum="6FA2960D38BB88AA" modified="2025-10-08" version="1">MQNKRKNGNQAGQGADAKKRRKGNGGAKVNNKNGADAAAAAAKPRRAVAINEQAWKPVQAPATDGSEGFGFDGFLGFEELTGFDVVRSGNSIQFVSTNPDDDDEDDVEETNPAHDEEFEGFGSDNEDDQDDEDDTEAAKPTQDKKSKDNKNKNDSTTKADGKADTKAEAAKEKKTKKKEQQEKAKKEKKEKAAVAKAAAAAAAAEPADELSKGGGFASLADMNMDALEDDADVAAWVPLNLSPPILSCLARLKFTTPTEIQSEAIPEILAGHDVIGKASTGSGKTLAFSIPIVQRWVARNNSRNAAKAKNKKAADSEEKKKMAPLALILTPTRELAHQIYKHIKELCAALPTSPYVCPVTGGMSVQKQQRELERADIVVATPGRLWDVLNLGPEFLEAFQNISFLVIDEADRLLADGHFKEAKEIVDALERQDTQHGYEDEDESDDEEGAGSKKRPRQTLVFSATFNKGLQQKLAGKSRFDLMDETQSMEHLLKQLNFREDVPKFIDVNPVSQMAGKLRERLLQCDAMEKDLYLYALIMLLGKKRTIIFTNSIDAVRRVTPLLQKLDLPAVALHSTMAQQARLRALERFKGSTHARGSILVATDVAARGLDIPGVDAVIHYNVPRSADFYVHRSGRTARANTAGVSILMCGPKEVTPTQRLVAKIHARDAAKSEKKAAANGEATEDQSKKSKKNTSSFIHTIDIDRRIIGQLRDRIALAKKLADSGLAKEMQNKDDKALQELADSLDLDYDEVFERTNSGPKKWRSASRKEELDSQTLPKNEVKAATYELKTLLAKPINMGVSERYLAAGGVNMRELMRNGPGDFLGHVDYLGLDDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTS6</accession>
    <name>A0ABR3YTS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meiotic recombination protein DMC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031349">
        <property type="entry name" value="Tfb6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781:SF1">
        <property type="entry name" value="ADR380WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781">
        <property type="entry name" value="TFIIH COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17110">
        <property type="entry name" value="TFB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37217" checksum="7448277508D5FB37" modified="2025-10-08" version="1">MADPAQTPVSSAASPGPGGFFQSGTSNAGLMSPSPSIRSTSSALGLPHPRSQPLRPGSAKEDLVRRYVSERLLQISRRFVKKYGIAEPTDTIIGYASMGELCRDVDALLNNLWKSGTPSLQVQYLLNIASELITWMDGFKPSPRATLALLRKLDYCFASLLIGEDLETHETLPGFEGGGNTTNFRRAGLSRTDMVRCRSIAEQSRVAVMDMFQRGPPDPFDENNNSNRRRRQDREGTVGTEASTAQGEDTDMERETTAEPTDDDATTLADATEDDEDEYENDDDDDINEDTQMGVARVYENTLVKLGEVLGDQPGRIGDFEPPVPDGGMVFEDENDDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTT1</accession>
    <name>A0ABR3YTT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46201:SF9">
        <property type="entry name" value="PHD FINGER PROTEIN MALE MEIOCYTE DEATH 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46201">
        <property type="entry name" value="PHD FINGER PROTEIN MALE MEIOCYTE DEATH 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="277"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="493" mass="53280" checksum="0F1BE6B2CDB7602B" modified="2025-10-08" version="1">MASAKRSSRIAGRQEQQKQEELLREEEQKRRLELDVLRKQEQRQRKAEKEREARLFSREKRLHEREIRRVQHREELAQLSEDSKSAENIPGRMSERKRQAEIEKNKEALRELDDEVEEEWAFDCICGLHGKIDDGQHSVSCEKCNIWQHSKCLGIDEQEAEKDDFHFVCNPCKRKAANAANGQQSNRPIIRIKINTSASEKTAAGPGPIGTEPPAPAAVQSTLPKPLLVHPAESTLAKKHEGSGINPDTDLSNIAPPILAPPGMHNGGSTVPVKVDGSSSSLPKSDANSDSSNPTTGSGYNTVQRSAQNGHTNPFVVPHPGLSQPDQSPRKSHAYGTIHDHPDPVPMLPNGLLPQPVVHLGPLTPTTATTTSSTQLAPASAQRTPTSLGTPRLQHSQGDRHATNSSMQSSPSLLPSHGGLSPTKHSPTVASSQATILPSGSPMSIVLPPTAALSPSTPEQILIPPVKPEGLAHRQSFSNPAADLASQPRASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTV4</accession>
    <name>A0ABR3YTV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Eisosomes component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SUR7</name>
        <name evidence="3" type="ORF">Sste5346_007486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36414">
        <property type="entry name" value="PROTEIN SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36414:SF1">
        <property type="entry name" value="PROTEIN SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="264" mass="28570" checksum="BD678F1454BA80B3" modified="2025-10-08" version="1">MALIHAPFGIGAALMLATSILFLFFVILGGVTNNTPLNKTYFLQADTTGITGAHDITQWTYLYSCGPNNEQCGKAHPAMPFGKVWDANAANAPPELIGKYGGNTTSFYYYYMWRFGWVFYLLALFFEVLAFFSSFLACCGRLGSGIGSLVTIVAFVFLTIAVSLMTATFVRARNVFHNAGRDAVLGGYGFGFSWGAFAALLIAMILLCAGATRKGTSKNTVDDGTNGTPAASGGRRWGRRNRRNRAGSFSKVNYEDGRLDNVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVE6</accession>
    <name>A0ABR3YVE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA damage-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007396</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="7">
        <location>
            <begin position="12"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="8">
        <location>
            <begin position="478"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="6">
        <location>
            <begin position="844"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="6">
        <location>
            <begin position="1044"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1007"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1231" mass="135328" checksum="E5B1A642F6BFA4F3" modified="2025-10-08" version="1">MAYVAPVHRPSSIRHALRIKLFSAHEECLVLSRANRIEIWRFTEQDDLALFHSQKIYGTVAMLEALRPKDSDTELLFVGTDRFDYFTLVWDEAQQSLETIDNFHDVGEKHLRDSQSQDRCVVDPSGRYMALLLWEGVLGVLRLKSRRDQSRNIDWMDQVRLSELFIKACTFLYTETGHPKIAFLYQSQSERRDAKLSSYRLTSDDHDKVVSRFDVNRERELNLDLDDIGAALLIPVEPNEGERRHNMRKTSNNTPGEPHLGGLLVVGETRFVYIDDTTQAKVLAQPKTPAVYVAWTRFDSTHYFLGDDQGVLRLLTLITDGPVIKNIEVFPIGKTSVASSLVYLASKRLLFVGSHHGDSQLYHINLTDDSSDSSDDNNAMTDGPVKSEPVTVPQPPAATATKDKGPEKKHKYCKLVQIFSNIGPILDFTVMDMGNSEDGKANEYASGQARIVTGSGVNKGGSLRSVRSGVGLEDIGILDDFSNVRALFPLRWRSASGKTDTLVVSLLTETRVFVFDSDGGVEEVDSFPGIQLDEETLYAANIKDASGVATSRILIVTAKAATLVDAQSGAALASWLSQHGKQITLASANDKWVLLSVEGKLLVSLSIDNGLSQAAVKDFGTDQIAAIHAAPQFQDTGVVGTWMVGTIAVLDLKTLEPTQASVSVRQKDDTASVPRSLALAQVMPKHLSSPTLFVAMDDGTVVTFSINMKDRTLHSKKSVSLGTRRANLYPIPQPDGTTYSIFATTEHPSLIYGSEGRIVYAAVTAQDANVVCPFDSDGYPEAIVVASLSSIKIARPDTQRQTHVQTIQMHETIRRLAYSPAEKVFALGCIDISVVNGTEVPTCSIKLVDEIMFRTIGMTLPIEGEQGELIESVIRAELKDAQGTPVERFLVGTSYIPGGQTTMVDDNGSLGRVIVVGIDSERNPYIISTHRMRGPCRRLAVLDGRIVLGLSKTVILGEYIETSSMSAKLKKIASFRAATYITDLAVHDNLIAVGDMMKSTTIVEYVPASGGGDEDDEDKGKKTTDSMDVDEDGNDNKKKEVTPAKLEGRARYFQSSWVTAVGHVEDETWLEADGFGNLSVLERNVNGVNEEDRRQLRAVCDMNLGDMVNRIQPIAVESAANAMVHPKAFLATVEGALYMFGTVSANAQDLLMRLQAKLDSTVTGLGKTSFASYRGFRSPERETDEPNRFIDGEMIERFLDLDEATQKEVAQGLGPSVEDLRNSIEELKRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVP7</accession>
    <name>A0ABR3YVP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF21">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="75"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="521" mass="58211" checksum="710230E56DD30FA2" modified="2025-10-08" version="1">MANESIQPAGSPTLGAGIADEKPAAVQHVVSADVETAMKPINVEDAAFIPVGGLTMTEEEKKLDRRVNRKFDLLVLPLLVILFVFDGMDKNNVGNAATVNFLETAHLSKNAVNNAASLLFVTFVPLQPVSAAFGKWIGVTRWMPFVMFIWGMLTISNAFIKSDGQFYAIRILLGACEAGFFPMSMFYISTLYPRFWLGRRLAIFYGSNTFAGCFSGLIAYAILQWENKPLYSWQYLFIVEGACTAFFAIVAFFWMPSDAGTAWFLTAEEKEWASIRMIRDSAHAHQAARGITKQDLIEVLRDWKIWLIIPGNMCASVIYQAFNVFLPLIVENLGYTSYRANLFTVPIYFVGSIGLIGAAFSSDHFKERTIHLLCALAIVIFGSILVVTLKSNVGRYVALCIMNIGTYTQTPLVNASIMNNTPHPNKRVLIVGFSGLGNVGGVIAAQLFRSKFQPTYHIPFYVALSLSVVGWLFYFSYRMGMIYYNKKRAAIIANWTPEEIEEENTNDVRLGDQKYTFVYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXG1</accession>
    <name>A0ABR3YXG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006919</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with histones H3 and H4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RTT106 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF3">
        <property type="entry name" value="HISTONE CHAPERONE RTT106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="5">
        <location>
            <begin position="275"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="377"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00037550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="499" mass="53442" checksum="3DBA71B20866D658" modified="2025-10-08" version="1">MASLDLERLSLAFQSRPDLVEQIRAAAAESPARTPLFNSIASYVYEQVHGADGSEPAHKRRKVDANGHSALPARQGTAPAKSQNGGEVDILSAAAAETVLLEVKDISVSIPQRKKYDLCFTPNYLYARASNTTTPVPGIVYAWKDFEHVFYLPVPEKAQVQYNYILFPRHSALASLAKPPAAANGAAPTTPPAAEPLVFTVPATAPKPGQVGGPSAGLAAAVSDSYTTLFHWAIEGQLRAVDNVYLANQRSIIVAADPKVFHSAARQPFRPTEKAVHVRAFRGSKDGYLFFLPTGILWGFKKPLLFLPLDRIVAVSYTNVLQRTFNIVVEVDLQGSGGAGGSGDGDGNGENENEEIEFGMLDQEDYGGISETYVQRHNLQDRSMAERRKAKRELAENARGEKANGGEGGEGGEGGANGGAVPDDGLTELQRAEQQLQDEEDEDEEDYDPGSDGDSDGSGSIDDEGSEDGDEGEGEEGDDDDDEEGEEGEGEEAEEGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY52</accession>
    <name>A0ABR3YY52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006464</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="754" mass="83111" checksum="EB4751F5ED575F64" modified="2025-10-08" version="1">MNPDEPPILDSITVVPRREPEPSVAVLPRRERSVLLGSDSSYVPLRSPSPQVLSLSPIKPKAKSKRKQASLPQLNCEECRDRKVKCDKQQPACSACVAAKVPCVPIFRRRLARGRHVPAIDAAMTTPNSLDEDIRQRVRRLEAIVTRVSPVPILPALRKTNGAAGILKQGVAPAPAQAQSQEPPLRSHAMQHPDHFWTDLSAEVHGLRDVIESTPEDAEDDTAQAQAEVSTQYHRPRDISVLGLSSMGASIFDPSLILHDRSLVSQLCKIYLYQVDPILKVLHRPTLEQHLMEDTPYLGYPEGHTSVVALDTAVMYVAINSMEEGQCRSLVGRDKSDLLAVTRQASEAALEKAGLLTTRDVTVLQAFVIYLAGRQVEEPSRAVWTLLAVAVRVAKALGIDLPRTKETFFLRQMRQHLWLTICLMDVQLAFNMISQPLISANEACLSPENIPRHINDADYAPWTVDPPLERGGLADTTYALIKYRIQAFGRQTHFVPLPGASGSDGEATSDANERLAKEQQNADALCDNFIKDLMARTFGIDPSQSPFAWLVFHSTQCFAAGAKAALLKNRPDKTKQGRPEFLRVSTQVLEKTVLMHTEPRGTSFRWSITVRWHILAITLAECYVCSKATNPDVQLLRQVWPTMEAAYAHHASIIGKHRGGRLSGPLSKLMSHARLAVEAVIGSENDRHVVAVSDSSITPAVGSPDLSAVLPAETASDLWGATWESCWDDLVSAVALDDDMAMFDTQFYVQSDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYK6</accession>
    <name>A0ABR3YYK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="6">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">IDH2</name>
        <name evidence="15" type="ORF">Sste5346_006597</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="14">
        <location>
            <begin position="53"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1893165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="382" mass="41065" checksum="76F92D11815818BA" modified="2025-10-08" version="1">MLAIRAAAGPARRQFRAAPRVAVSISMQARFYSDKKPVAQFTGVKGSDQGLYPVSLIEGDGIGPEISDAVKDIFKAAKAPISWEPIDVTPIIKDGKTAIPDAAIESIRKNKVALKGPLATPIGKGHVSLNLTLRRTFNLFANLRPCRSVAGFKTPYDGVDTVLIRENTEGEYSGIEHVVVDGVVQSIKLITREASERVLRFAFQQAEEIGRKKVRVVHKATIMKMSDGLFLSVARDVAKEFPGIEFDDELLDNTCLKMVTDPLPYNDKVLVMPNLYGDILSDMCAGLIGGLGLTPSGNIGDECSIFEAVHGSAPDIAGKALANPTALLLSSMMMLRHMGLGEYATRIEKAAFDTLAEGKALTGDLGGKAKTHEFAAAIIEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZB1</accession>
    <name>A0ABR3YZB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006940</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="38"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="536" mass="59074" checksum="3C028737C166F0B9" modified="2025-10-08" version="1">MTTDEKTGQVQQAKQATLREHALGWRESLRLYPKAIAFSLLFSSAIIMEGYDLSLTGSFYGYTAFQNKFGDQPGPGGVGRVVSADWQTYIQNSGMCGQIVGLFLNGYVTDRFGYKKTMIASQLLMIALIFVPFFAQNIQTILAGATVLGIPWGVFQTLAINYAADVAPVVLRPYLTTYVNMCWVIGQLIASGVLRGLLNRSGDASWRIPYALQWIWPPLIIAGTLFAPESPWWLVRAGRYEEARTVVQKLASPTLADEADDAVALMVETDRLEREVSQGTSYWDCFKGVDLRRTEIVCVSYLAQAWCGTSLMGYSVQFYERGGLDTSHALDFNIGQSAIGLVGVVLSWVLLTRFGRRPIYLTGVFLLLILLVVVGGLGFANPDDKGPSWAIGTLLLVYTLVYDAMVGPLCYAIVAEIPSTRLKVKSVVLARNVSNIAGFLNNSLMPRMLGVNSWNWGAKTALFWAGFCVLILIWAFFRLPEAKDRTYGELDVLFQRGVSARHFSSTAVDQFEFADEDGQPKGHATAGVEEVEAKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZB6</accession>
    <name>A0ABR3YZB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Vacuolar protein sorting-associated protein VTA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_006225</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.270">
        <property type="entry name" value="Vacuolar protein sorting-associated protein vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044538">
        <property type="entry name" value="Vta1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039431">
        <property type="entry name" value="Vta1/CALS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023175">
        <property type="entry name" value="Vta1/CALS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041212">
        <property type="entry name" value="Vta1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04652">
        <property type="entry name" value="Vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18097">
        <property type="entry name" value="Vta1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vta1/callose synthase N-terminal" evidence="10">
        <location>
            <begin position="17"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Vta1 C-terminal" evidence="11">
        <location>
            <begin position="393"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="44604" checksum="344E9520433DAD7E" modified="2025-10-08" version="1">MADALASLRQADANLYKTAMRAEQLQNAEPIVAYWCDYWVLKQILSKGLHTSSPDILEYSTKLMNRMEHTKDTRGTEPAIADDTEGQLYIEQFAQKRLDSAQNVVKASKVTATTANTFDAAATLFGLVNIWGAPDTETIQKIKYAKWNATRILRAIKDGKDPNESNPKPDELPLAKDDESAVGALSPGSEVPPSASASAPRPVTIEDEADGNTLAPSADSRTRRDSAGVSLPHSPASSAAAPASTAGGIPDLPPPASGALPSFGSPTAPPAAAASPTIYSDPDALVPPANFSPTVPTFSPPTAPPDLFYQPPSQEQPSAPPSAPPSAPPPAASVPPNNGYFVGASAQTPRAAATGYPPAYNNRVVPQPSAPPPPPAAAAPSQSAGGAVDDLAMVNAQKHAKWAISALNFEDVSTAVRELRKALEFLGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZJ1</accession>
    <name>A0ABR3YZJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_006525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF53">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="55"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="547" mass="60789" checksum="A25538CD1DD8A5BB" modified="2025-10-08" version="1">MASNKVIPTENELKAFNLDDPQTIELIQHARDGHEADAKLTLLEAVKKYKKACFWALFLSTSLIMEGYDLVIITSFYGQTQFKERFGTVDPATGDKLITAPWQSGLSNSSVVGQLAGLLINAWAQDRFGNRPTMMAFMAWLLAAIFIPVFAPSLPVLAFGEAMCGIGWGVFQTLSTAYACEVVPPIVRPYVTGYVCMCWGAGILLSSGVVRAVASIDGDWGWRLPFVIQWVWPLPIIIGTFFAPESPWNSVRRGKEDEARKNLKRLREDTPDRDLEVEAALALIVHTMRLEDAETEGSTFFDCFRGTNLRRTEINCVVWAAQILCGNAILGYSVEFLEVAGFNELQAFDLNISLSACYIVGGIICWLLFPHFGRATIYMSGLLFMFFCLLAIGGLGFSTNPNANIAVGILLVISTLVNMITIGPVCYPIVSETPSGRLRYKTIVIGRFVYNLTGIFNNSVTPRMLSALSWNWGAKSGLFYAGTNLLCLIWCWFRLPETKDRTFGEIDILFENKVPARKFKYTKVDQFAHQGEINEKSGAVEHVDEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z013</accession>
    <name>A0ABR3Z013_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006344</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="76"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="558" mass="62377" checksum="8DB975310A00720E" modified="2025-10-08" version="1">MSPAPAPGYGDSVTVSTTNNTSSTGNGDFGKRTKVACKSCHRRRVKCDATEEQPCWHCRLRGTSCELIESRRGKYIRKKSTAGTNPSTANANANDNRRSSTATASSAVVKSTSPPGILTPHTVHGDTRSPDPTANALGQPSPPSTIHRSSDGGDDNQTATARSDGDMGMDVAATTEPPESEGPEMLYTRILEGDYAANSPPGTLPMDNVRYFYMGEPFSLAFVIRSLSDNPAMQNMQNGSLQLHHPIPHTVPEYAQDGAEAFRDTDPAVRASLNLYGAFEMLPRAVSDELVRLYFQLVNPAYPVFDRTEFIALYRQNKVSLLALHTIYFLSLTVCGEETIKAAGFSDRFTARRAVYLRAKALYDTGYEKNKITVVAVLFLFGFWWEGPEDQKDSWHWLSAAVSLAQTLGMHRSTVHSGMHHRQRSMLKRIWWSIYIRDRHAAAALGRPCRIQDEDCDVEMLTVDDFLIDQENDRSLIIEETEYQRNYVIEMARLAQILGRLLKREFAPHGAASPAFNADIYGELEDWERRLPHDLRRTAVDESLEAPFWSCMLYANYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z080</accession>
    <name>A0ABR3Z080_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lactase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LAC4</name>
        <name evidence="8" type="ORF">Sste5346_006217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF1">
        <property type="entry name" value="LACTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="7">
        <location>
            <begin position="795"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1095" mass="120697" checksum="536B0C2748BFF870" modified="2025-10-08" version="1">MGLPRQEVAGRHDYENEAVIRRNTLPHRTYYLPPEATLCLNGSEGEWQFHYAESPLEAPDAEKESSPSSSSTTSPDNWHPITVPGHWQLEGRQRGHGDAWGYPWYTNVQYPFPVTPPHVPAANPTGTYRRVFSVPTEWTERFPGGNGPQLRLRFDGVDSAYHVWVNGILVGYAQGSRNAAEFDITEVVASTKSTEVTLVVQVYQWSDGSYIEDQDQWWLSGIFRDVHLLGFSSTTSIDDWFVNTDLDATYTDAELHASVTVRTAEPAELTLHLTEHKDTGVTVDELTVKVEPSTTSPVKIRLPVKNPHKWTAETPNLYRVELTLRPLSGKDKPHTVHQTIGFRKVQLIDGLLCVNGVSLRLRGTNRHDHHPLHGRAVPHDFMLHDLLQIKQYNLNALRCSHYPPHPKLLDLADELGLWVMDEADLECHGFYDVVARPLDIPEEMDYEQRKKMTFPKAAKFTSDNPTWRAAYLDRMEAMVQRDKNHASVIVWSLGNEAFYGQNHKEMYHYSKKFDPSRPVHYEGDAHAETADMYSYMYPSVNRLAKLAKNEGVDPKTGKFEKPIVLCEYAHAMGNGPGGLEDYEELFRTHPRVQGGFIWEWANHGLWKEDADGKKYYAYGGNFGDEPNDSTFVMDGLCNSKHLPTPGLVELKTVVQPVRLSLDGKTLTIQNLYDFIDLSHLTLSYRIENFSSSSSKNTTTTLFTSGEIELPKIAPHGGKGTLVLDGIDTSAYSGNADVLLTVLLSKKNVQPGLKGVAHFQQYLTTERKNNLQLAPLTISPSSTQTATVLQSGANITASVGQHSFVFNAAHGSLTSWTINSTNGGSPVVILGSESSSLPAIAPGFWRAPTDNDRPLSVPYWKRFGVDTLHLHRVISVGHSTSGDTATVAIETVIAAPVLGWGWNCKTTYTLSGRGLVVAVSLAPFGSAPDHVPRIGLDVRANKSFQNYAWYGQGPGESYPDKNLSQMVGVYKANLEELQVPYDVPQENGNRMGTGWVTASAEAGGVQLRATLSDAATENTGHASGFSWAAGPYSAQVLDAAAHPCDLVGKEDPDAVLLRLDARVAGVGSAACGPGVRSDLLAKVEATSFAFTLEATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0W1</accession>
    <name>A0ABR3Z0W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="188" mass="22110" checksum="00371F1CEE5FCE8F" modified="2025-10-08" version="1">MFPNDNRDHGDQFLGEHFDHPVIHDDESEIGSDFDDLGFEPTPLQSNPDLPRRRTRTRAQRMINFRRKWDTQYTVGFLGYDSDPATDSHYMPHHQDMQVQVARPNRHGYNTAGMSTAGSSEWVPERYSVVAYHQAADFIEHVRDAQSFILGVDGPDRRASMYRSINHTYLTDREHRQLYRLRELYKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Y0</accession>
    <name>A0ABR3Z1Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_005992</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF111">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_1G10100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="291" mass="30579" checksum="69743E7745076956" modified="2025-10-08" version="1">MSSPRLVPRSLEGKYAVVTGFSRGIGAAIARTLATKGANVHGVYTSDSSTKAALELADELRGDHGVKIAVTQADLAEGESAAAKVAADFKEFSSLAGKAPQLDILINNAGIGGNHRLGEVPVADFHRQYAVNVLAPILVTQALMEWLPHDRSGRIVNISSVSSSIGFATQTVYGGTKAALESMTRTWARELAERATVNAVNPGPVEGDMYFAAGEAFWKEMDPFQQACPLSAVRPGIDDPTLVKLATAKMGGRRPGYWREVAAVVGMLCGADSAWTTGSVICASGGLKFQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2N9</accession>
    <name>A0ABR3Z2N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribose diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">YSA1</name>
        <name evidence="4" type="ORF">Sste5346_005581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.13" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="55"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="222" mass="24100" checksum="D21C6E566CFE3A14" modified="2025-10-08" version="1">MSSLPRVVSRKPLPHNQAQWTKLVQVTYQDADGTSRIWESAECTTRPPATKDNPDPVDGVDIVAVVSNTEGPPRIVLIKQFRPAVGCTVIELPAGLVDAGESVEQAAVRELREETGYAGKVSASTAASLAPSPTLYADPGFGNNNLQVVYLDVDGSDPHNQDGQRQPQLEEGELVQEVFTVPLADLFEMVRKFAYEDGYAIDARVGTLAEGMEMAKRYLSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3R8</accession>
    <name>A0ABR3Z3R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">KCS1</name>
        <name evidence="6" type="ORF">Sste5346_005423</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF21">
        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="532"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="737"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="779"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="941"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="969"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="355"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="539"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="558"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="754"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="787"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="822"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1269" mass="139676" checksum="1363B287FD226EF3" modified="2025-10-08" version="1">MAAQESQTDYGTRSSAGGNDLDGATSTAGLDSLDTGSRQIKDRQQSFDEPAGHLDLDIDDGADRNARDSTPVASQQLPPLQLHTTARHDLSGTAVPDFTPTQCHKGLNPPTQTAPAAEGAETTNLSTTPTLSSATMAAPPAPSTPTPSPRRQQQLSSSSIISTSSTSTTNDYPTSSDFVVVLRDAKQQVSGKDPTARPNPPLYFSVQSPNADRSSSREYFDNANRQERSPTSPSAQMSGASIDRAPIPIPISKPSGSSVLRSRATHSSTDDTDTDSRNALDALTKRRANGRRESVDKSDGSADTAVAVEDGDDSGEEKISALFVPHQSVEEGAETPPLGSTPNAAIAAAAAAASSVGTRQPTNRETFSTWRSGSSTTTEPEAVRQTPSIPSSDLSPEFSNKIRRQMSHIDQQYAARIASHPVTPNEEPEPAVSDSAETAVEMPSRPMSQYFEETDLDIEPEPSQPRDAIELIPYKHQVGGHTTLWRFSKRAVCKQLTNRENEFYERIERYHRDLLPFLPRYIGVLNVTFHKKPRRKSTMKKDDMAAAERKQIGQGELSAVMKGSSADSSSAVRDDSTKSSSDRPAAPTTTRIISQSIQNSQTQVPTVTFIDNQHILPRHLLQPTASANHTPRGSYSAATAAESNLLREHLQRAVGSVEQRGFVVSEPPSRSTATRPTLEGRHLNSWGATLVNKRLRNEVFNDAFLKQPVDVQKYQKGKTARAVPRKILQQHVLRSSNSESTLVTERERRASAKAAQQDQFTSPFKTDLAPAASMMVTQSDMGPTAKELSDKTVIDDDVESPKDVTGTSAPEAQNFVDQIHPQQRRRRYSGTGLRRKPKNVTDPRGDLKYYEGADEAAYKADIDDLTTTNTTTTNTSRSSFNPEMALAAFEDLFVADQSTPKAPAADDKNGNHSTISAMDIKKPQHNGHGFSNLSHQLEMDQDAATETTPVQEPAPFLGDSNALTLAGSPSEFRKIPRPINPKEAQTQSGSRQEYFLLLEDLTAGMKRPCIMDLKMGTRQYGVDASPKKQISQQRKCANTTSRELGVRICGMQVWNVSIESYVYHDKYFGRNVKAGQEFKSVLREFLYDGSNKNSILRHIPIMLEKLHQLENIVRRLRGYRFYAASLLVFYDGDQSQTNKDDSSGMLTGGEDTVIEDSTTDFATDNEDMSEVVRRRRQRRRDKRDIDFKMADFANSVTEADAAKDRPCPPQHPSEVDRGFLHGLQSLQRYLLQIQREVRSEMDLAWQLRNLDMGDDDLITDWDDAGDVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z483</accession>
    <name>A0ABR3Z483_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DLD1_3</name>
        <name evidence="12" type="ORF">Sste5346_005252</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="11">
        <location>
            <begin position="169"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="65042" checksum="47B78DAD680EAF3B" modified="2025-10-08" version="1">MASPVLSRAAAPFSRYCSRTASIVTKTSRGPTSIPRQRTFSSFAPRRQPSPSSPSPTSTKSIAGTTAAAHPVSWWTSQRAFAAAAAAGLAGWGLAAVYFGGWPGSAAIRLDSEKSTAPRYANMRGMEVAIKEIRREIKKAGFENSEDIISTDPEDLLAHGYSEWSSTNPDGLPVAVAYPRSTEQVSVIMRVCSAHRVPVIPYSGGTSLEGNFSAPYGGISVDFAYMDQIIQFNKEDMDIVVQPSIGWQDLNDQLAKMDSGLFFPIDPGPSAKIGGMIGTNCSGTNAVKYGTMKDWVINLTVVLADGTVIKTRRRPRKSSAGYNLNSLFVGSEGTLGLVTEATLKLTVVPEELSVAVVTFPTIRDAASAAAEVMQTGIPVAAMEIMDEVQMRVVNLGGATAPRVWQEMPTLFFKFAGTKASVRENIENVAKITGRNRGSNFEFAKDAREQKLLWSARKESLWSMLALRKAGEEVWSTDVAVPFSRLADIIEVSKKEMDDLGLFASILGHIGDGNFHESIIYNRADSGERAKVEACVKNMVKRALDMEGTCTGEHSIGWGKKDSLLLEVGPATLGVMKAIKAALDPHWILNPGKIFDKQYLAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4R8</accession>
    <name>A0ABR3Z4R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DCN1</name>
        <name evidence="4" type="ORF">Sste5346_005090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="3">
        <location>
            <begin position="117"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="333" mass="37684" checksum="1BC8191B83B395E1" modified="2025-10-08" version="1">MVFNVKKIFRISSDKHGRKEQQQQQLQTDTDSPSEDDVYSQRLRNGSSNRPWASSSSTSLWRSKDSNQNQQNEQAQNDSSSSLKGVRKKASRIGRRGKESEKYFNNMAPGGGSLANAAEPKLDKMFDELRNPSEDAKDSLGVESTMGYLTSLGLNPESGEVFVALELVQAPNLGEITRKGFVDGWKASGNATLEDQTKYIASLVKHLGSDPAYFKRVYRYTFGAGKEPDQRSMSLENAIEFWKVLFAAPGRPWKTASRDWTPLWIEFLQEKWTRSVNRDMWNQTLEFAIKCSEDETLGFWSEDSAWPSVIDDFVSWSTEKGYTGVKKDSMETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5E4</accession>
    <name>A0ABR3Z5E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF50">
        <property type="entry name" value="MFS SIDEROCHROME IRON TRANSPORTER MIRB (AFU_ORTHOLOGUE AFUA_3G03640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="571"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="89"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="605" mass="66822" checksum="707FC2BDF201B738" modified="2025-10-08" version="1">MSHEATIAMDTIQAAPAVEVPPTEKATAEKSDLEIAAAPVAAEADEGVLGEDADAEKRDMEMPGQDLQQGVQDVEAITLSWSKWHLAAVLFNIWMLYFVNAMQSSILSNLIPFLTSDWESHALLTTIYVVSDAMSAAVYIPLSKIMDMWGRAEGFLCMIACALLGLIMMAACNNLPTFCAAYVFYNIGFYGMTYCVDVITADVTTVKSRGLAYAFTSSPYIISAFAGPKAADDAVYDNMRWTFGCFAIILPFVAAPLYFILKRSLKKAENFGFRSQEKNNRTLAQSIWFYIIEFDIIGVLLFSCGLAVFYLPFDLASLAPNGWASGYIIAMIVVGFAVLCFFVVYEWKIAPKPMINYSILSDRTVIGACLLDVTYQISYYCWDYYFSSFLMVVNDLTVAEAGYVGDTFDVVSGVLLLGVGYVIRRTGRFKWLLYIAVPLYIFAQGLMIYFRRPNQNVGYLVMCQIFISIGGSVFILIEQVAILAAVDHQHVATALALLNVVGTVGDGAGSTICGAIWQNTFAKALYMYLPADALDNFDNIYEDIYTQLDYPVGNATRTAIQESYGYAQTRMLAAGTGVIGLALIWMLFIRNIDVSKVKQTKGMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5R6</accession>
    <name>A0ABR3Z5R6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein HRI1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11693">
        <property type="entry name" value="HRI1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11692">
        <property type="entry name" value="HRI1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.320">
        <property type="entry name" value="Protein HRI1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031818">
        <property type="entry name" value="Hri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038744">
        <property type="entry name" value="Hri1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043047">
        <property type="entry name" value="Hri1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16815">
        <property type="entry name" value="HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="266" mass="28648" checksum="14C138CE77FB2A52" modified="2025-10-08" version="1">MASISLRQSIAWLPDPHSEATSTVVLTSPQRRFVDVRILLPADAKPSMADGSFSAPSSPSTLGLDWALAGTSSSTPVADTNGKFSDGVWRHWVDSRYADADSQVDAGRNTEQPDGSVLEVGCMENPATGQVAAYEEVWRDIAPVSSFPENGKPPRCLVLQMHNTETNDRGVVELLGQFCQGISRTQKEGVTVERWQWLPTESMARGDGRNEVYRSSSPSSTWQMLFRHGSGSLPCVCAITGAEKLAEGETVTSGGATWTVVEATDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5R8</accession>
    <name>A0ABR3Z5R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="97"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="427" mass="48032" checksum="F9E62A9982984FEB" modified="2025-10-08" version="1">MANPLCLHCYRTYETIRSSTFLVSQHEAMSSFRTISHQQQKRGQPLSKMAFVQESNAFADIYAPGQDILRQQTSPPASRKTTPTFVPVYPPPTTKFPPPINSLPPELLDQVLSFFATPALLPFAGVNRRFYNLVARLLYRRLRHAVALANHQLILACYHPSAKISSPYLNCTYLGTEGLDLPCFDTDKDDGSPEGTLLRMPTMYSRFRPVPPNESDVHVRNYRAIRRTMNFFLLSDTTSGGTAATALQTVKEGDSDIPLVSYDVHLDEGELFSQLCTVTNLVKTSSQPGLFLNCVNINDGVIRVWRDWLDRRASGEEKEEPSKRDGIASIADTDSHVLWAYTGKHVGMRFRVAERSVPQARLDAAAAAQPQNERFRRSTMPQEEPPVSFVLEYEELLVRTYELLLAMEAVEVQDETQETRGVVVSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5X1</accession>
    <name>A0ABR3Z5X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Maleylacetoacetate isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF4">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="104"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="25262" checksum="56C6DFBD67A03F12" modified="2025-10-08" version="1">MAANDISNAELTLYTYFRSSCSARVRTAAALKGITVTSKYVNLLKGEQSASTYTDNVSPCGTVPAIVIRFPDGSQSTIRQSMSILEFFEEAFPDKRPLMPGVDQPLQRATIRDIINIIGSDVQPKTNSSVIRRMQGLGVEATDWCNETMVPGLRSVNAILQESAGKHSVGDEITLADVFISPACEAALRWGVDLTPFEAITRAYNACKDLPEFVAADWKHQPDTPEQFKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Q6</accession>
    <name>A0ABR3Z6Q6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) endonuclease 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">APN2</name>
        <name evidence="13" type="ORF">Sste5346_004687</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF4">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="12">
        <location>
            <begin position="875"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="436"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="488"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="640"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="706"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="765"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="789"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="933" mass="101320" checksum="C87FB82E0875CF88" modified="2025-10-08" version="1">MTVRIVTWNVNGIRNPLKYSPWNKDRSLKVQFHEDEQARARSSETRDKRNADADGAMFDILEADIVCFQEVKTPKASLTDDLVFVDGWDTFYSFPHSLTGYSGVAVYTRDSKCVPLRVEEGVTGILKIPGTQTRYVDAPPDKQIGGYPTDRQLRRAAVGRDVIDSEGRCLILEFPLFVLINVYCPARRNHERTGYRNTFLLALDVRIRNLAAEGKNVVLCGDLNIMRDQLDTAGIWGHGGIKVLAEALEFDENYMTMRAPKLLSQLLFNSRTISDTGTPFIDETTETRRPPVLYDTCRELHPDRTGMFTCWDTRKNHRPANFGSRIDLIMCSPKVMQLVQEANIQPHLLGSDHCPVYVVLQEAIGDDDAVEAGETAESKDMAYTLDYLNPPGRFVDGHNVLPPDEDTALLKKRFPQSGRRMPQFSNRRHIASMFQRASKPAAPTPVAQDQKSSAHPAAADTSVQPSTPELPAILKAEAVELVESDFEGDDGAGMIEDEEEDGNNVEDTDDANGAPGTVEEDERFEYVARSGAVSKMSKTQQPTDLPQASIKDNEGRGSQKKQRPPPLHANEDALSSVVPSVVSPSLPSRPLPLTAADENQNGGVDADVGVSETSAVHGCRSQTPSTDLPFERGRSKTPIVESSTSTSERKPNQMQSFWGDRSGVDVSRERGNTGASGESGEAEVALAPPPLTAPSLASPPPPPKPKTALPASQSATPSLLPSSTTTATRRSLARSQSGASNSSTANTANASLSSSSARPAKKAKTSANSSSSASTGIQMSMNMFLTARPAKEKEEHKKQPPPVAESTPVPQSQPSPSPSTAVASALDEANTAAAADNEAAEWMTAEEVDAAFKNLDAAKASWSRLGLGQRQAPLCEHGEPCKTFVTKKAGVNSGRSFYMCARPPGPLGKKEKGTAWQCTTFVWCRDWRPDRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6V1</accession>
    <name>A0ABR3Z6V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF37">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="38384" checksum="75955D89BA1E2556" modified="2025-10-08" version="1">MNSKFWCVQLIPQIWTNWRTKKTDGLPALMMFLWGVCGVPFGAYAIMQNYNIPIQVQPQVFMGLCLISWSQILIYGNGWSVKKAAAAGLALAVLFAGIEAALILALKPIYERGNEAPALAVGIIASIFLAAGLIPPYFEIYKRRGRVVGINFVFLAMDWSGAFFSLMALVAQNTFDILGGVLYVICALLEIGIFMSHIIWLIRTRKLRKQAKAEGKTFDELAAEIIAERGADNFPFAERPLHPFFTSAWWRNRFNGKHMKPNALDLEAATARRNDEEQALPTNEKAVPTEVPAYGGPSHLTAASSTPAVATQSAPNTATTDDACLSRSCSDSVAPTQCGEIETEFDEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6X0</accession>
    <name>A0ABR3Z6X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c oxidase assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11371" checksum="38131675F3F1FE13" modified="2025-10-08" version="1">MPPPNNVAPKVRVRGMILTIGIAAITIVGTMAGAGLKTDIEKKEARKMAAEPAGEDDLIAALETRRRGLVQTRESWEKKAEVLRERMASNAQRSIGGGSGGSGTESGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7A9</accession>
    <name>A0ABR3Z7A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF1">
        <property type="entry name" value="AROMATIC RING-OPENING DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G00640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="15"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="288" mass="31717" checksum="B9F29BC1688E60DA" modified="2025-10-08" version="1">MGKTTSSTGLSPVVFASHGSPFMCSKESTSSKWWAEFGKKSLASGIKGVVYIGAHWEELGDRIRVATKFNPDKVQMDIVPRSFWGDYRINISQDLADRVIRLLQDEQFTDVQADPTFDWHDDTITPATWMFPEGTPPATVVSLNARYNPVFHVRIGMALAKLRSEGILIVGTGGAVHNLYRNNWVPMLSKGDNFQVGSTPAKWATDFERAVSDGPALAGALVRLTQSPGYKAAHPTDDHFFPLLVAAGAASVGYDEGRLMAQTWELQHMCNDQFLWGDWNVAPVGVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7P1</accession>
    <name>A0ABR3Z7P1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004836</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="188"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="27038" checksum="18CA8B3CE94C8D25" modified="2025-10-08" version="1">MPKTYIGWLKDKTLRSGRKSTSAKNNALSSTLPSSPTAVESSRPKHDAETNVLGSKPSFDDEAPQDAYAVSIRTRPPPYYDKEGSLEGTGMLRGRLWSEAFITFNDRSPELADTYKALHVAAMSPYDSLNIIRLLLEHGADGNARDMRGRMPLHLAARSNCMPNLRAPVEHEEHDGDEIVDMHARDMYGNEVMHFVTNSAAQQTDVLQYLVDHGANINTLNGSLCWNLTKGPALYLDPKVAELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7X9</accession>
    <name>A0ABR3Z7X9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S acidic ribosomal protein P2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPP2B</name>
        <name evidence="8" type="ORF">Sste5346_004403</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001859">
        <property type="entry name" value="Ribosomal_P1/P2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00456">
        <property type="entry name" value="RIBOSOMALP2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045556744" evidence="7">
        <location>
            <begin position="17"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="111" mass="11146" checksum="2D81EB01032B699D" modified="2025-10-08" version="1">MKHLAAYLLLTLGGNASPSAKDIKNVLESVGIEADDERLNTLLSELKDKDINELIAEGSSKLASVPSGGAGAAAAGGAAAGGAAAADAPAEEAKEEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8C1</accession>
    <name>A0ABR3Z8C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDS1 winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057511">
        <property type="entry name" value="WH_GDS1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25318">
        <property type="entry name" value="WHD_GDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDS1 winged helix" evidence="2">
        <location>
            <begin position="156"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="479" mass="51676" checksum="AB07E7418F1674C6" modified="2025-10-08" version="1">MPYNTRRKSLSLPSLGIHVPVSNAARAAAAAAAVAAAATKTNANTVASQEASSTSSNTSSSSSSATQRQLTPVSDSTTNMAPPTTTTTSSASPKRTSSSSASSDAQQPSSKRAKRTHEVASASNTKAAAVATPPQSPKRQASIEMDSSDVEEVEIDMDEVNDDIVEAVIIQLKATGNRPHLIKELSSILMHTLKSVQQSANPCAIISSRLASYMKRACWSATTKCPLTKELENIHPRRTYYFLTTCPHQPLPDASSVHFIVPRTSIVTPPLSSAASNSEVAEEERRRELSPSPEVDLSSPEFDDLDDDIPMPGTPIAHFSNPRYSRFSRYHGHGHHRSASSYSSRNHRGASPPLEKDEKEFTQTAEGLQKQKHAGSRFLLSPAAIAAQAAPPSAAAAHSMFLEDNGREDSLMFGSETAAARHVDFTLMTSPAMRPVFSLGPKRDHEAENWAKLDSMVNDWDRCPENVELDELDGLLDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9U6</accession>
    <name>A0ABR3Z9U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045555094" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="58042" checksum="F9FF6BD1C682942B" modified="2025-10-08" version="1">MTKLPLRVAWLLIAAASWTATTQTANALSIPIDISVPVNDLGLTIFDRATSECASGFATCPGFSLPGDFCCPSDSVCNVLAGNTTLLCCPTGQSCTIINPITCDITQQDPETHPEAPIKTSALNGVLTKCGGSCCPFGYNCNGNNLCVMEVNQNAAPLQNVPTTTSTKSTSTTSSKTTSTSSSTTLAQAGGAQMTTTADSSITVAVYTGTSTVATAASTSTGTSGTTGTDVSESAVASADDKSKNTSTATIVGGVIGGLAGLLLVGAAIWFLCGRRLRKNGSKSIGGIGGGGGGSRLGSGMKQRDPMNFMSDTNKLTRSTSSFGNIINNPLSISSPKPQGDATAFRTDFIRKLPSSGDYSRPVTPASSFGGGIGSSGLDAASSTVGSVGYNNNRPQQQQQKLGSPSPLGIRLDRELPSPPSPSPPPLVLRRSRDSTSVTPIRGMRNSGPRTQPSKHNPREPSMEEINVGVDPSIIAFGGNFTISPPGTLLPPGRAAAATAALASVTSNANNTNVNNGGLTVPGAGQDRNRNNDRLTTFSSLLQAANLDPERPYVPNSVQSSPASRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAQ0</accession>
    <name>A0ABR3ZAQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="1">FBP aldolase</shortName>
            <ecNumber evidence="1">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="290" mass="31663" checksum="2807C07544E67DFD" modified="2025-10-08" version="1">MTRPPLSENRSMAILNAARDGGYAVPGMCCYNIESVIATVRAAEAARSPAMVLLFPWAIEYAGDALVKAAAEAAHSASVPVSLHLDHAQTPELVRRAADIPDAFDSIMCDMSHYEKEENLKLTRELVQYCHERGIATEAEPGRIEGGEDGVAETIDLEAVLTTPEQAEEFVATGIEMLAPAFGNVHGEYGPRGIQLEYDRLDSINKAVGNRVRLVLHGADPFDEKIFRRCIDAGVTKININKGMNNHYAATQEEMRGKPLTSVIEAGTNRMQAAIEVYMEWFGSKGKADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBL8</accession>
    <name>A0ABR3ZBL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="913" mass="99161" checksum="D160CB96044D3F9E" modified="2025-10-08" version="1">MQSSGVFDETSSLADSAYELISSTDGESQDGRGTDSLAASITSSFNIYPRADDVLSLNGNETAYDDEDDEDADEDEVEDEEDDASSDGGHLDQSSGYLPTQTRNTPGHSQLYHAGHGNGEDNNGARRSSPADSIRYAEQALCNPSTQSLSTLEYDSSHGDIAGCHSPLNQSIEFDEGADVKPYIEKVSVKHTIREFSEGESAIIAANMDIKPADAPKRMAATICQTMSRHCLSTGEPLRVLYVGNDGALDDIIRKISSAILASASSPGSPSPDAERRHSSTPGIYNIIPISSFGSSKVPEIDEIQLMGVSQYYIKVDHCIHAEETVYEGESFPNDTIYSIELESGTSHVSVFDPSGSTVSPKWDLPHVAVFYVSGNDDEQAEKTRNAAWEFMTRHAVPSIFISHTQSFSRSPFSGRWKDFVDHAAVHLSLESRDPSKPATPERLSIDLVSFLNIDARQMNRNLAYLTGLKDIPPKEKKYAGKASVIARLLGALLHPGKNDSHEAHRAGRAPLLSILWRIFFIILTAFCATTLVDHHIAAPIRHRRAVKEEKAFSANILSSASVAATQTRLADSARPTQSTALSSICSAPSVAPTVTISFVSTKTVEVHVSESTSLPSQVFGGYLTDSAHNQGGNKRASDAKIKSTGCSIHVYSSHEILVKVPAATKTKWLAKGAIDIDVWRGQKILKSKLFTTSEGIIIEIDQKDAFGVMSVSIVTTLRPKINETFAVDFGQPTASWFLEAGLTMCQESFRAAADALSVYADEHNISLPYVAKAQAILGNASSLIHSASQGFTAFKDDVTKGYQRLRPDVLLEKATHEAQSLVGNLVPTTDVAEKMRGDVRLTVRRAQVASKLWWLRVQGKTHEHDTYEAKAAEHIRKLELDAKAGRVIAGAEKGVPEGVKVTTQGRSILWLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBP8</accession>
    <name>A0ABR3ZBP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="469" mass="48659" checksum="21F2AEDBFB184FE7" modified="2025-10-08" version="1">MTNEFIAVFHNPTYDDHIGQAMRIMKFFATSDPQARRLSWILDALQEVVDKQAGTSSATTSAGTDVAETASGPNTISDDPKTSDQKTPVRNTQRAFRFEFPKDFVPGVTDPIDTFFVLQNSHVTAGGGAVPFGGINTAAGSQIGSSRLEPRSQLAQPPTDANSGAEASQVMSQLSDSINVDSGFTGRLQGGNEHSQPSLLGMQSTGMSATMSAMPSGLAKHGSMIYTGEGGEGATVGNPLVLPPPFSMSTAIPSTDFSPQVQPQPQHHQLHPPQHQHQHSMDFSGGMTAKGLGPEAYRAMENKTTGDPDGTDSIETDGEGFDFDVLWNWPNQVGQVAVDGTPGAGVNMSGASMGLAGLGGGGAPNTMSYVHTAQQHQGGTADMSAYGDASRGQGDGQGPGPGGSDIEMKHGSAPPHNEPMPLPPMYPPYGMAPLSSNVGGPGFGMSGVHGYGNLVGPLNVPLYTTTDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC50</accession>
    <name>A0ABR3ZC50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="329" mass="36235" checksum="7D69EB9D1956A16A" modified="2025-10-08" version="1">MQLNAQLATWRPPQITPWQRFRRDPAIFLARALYSQRADVVLPSPTADPIKIICISDTHNAQPTYVFDGDVLIHAGDLTNKGSFAELQSQLSWLQSLPHAHKIVIAGNHDLLLDPAFSEKYPDRVPDESGGEGTSVEDLDWGGLTYLNDSSTTLTFESPSPTGSVPSRTLRIYGAPWTEQCGLFAFQYPPVRERVWAGRIPDGTDIVVVHGPPRGHLDQGGKGCPQLLREIERAKPKLVVCGHIHEGHGREDLLNDNLDRAYHAVETGDRGLWGVAVLAGWLLWKNLWAAVWPTVTSKGTRLVNAAVMTRGWTGNADGPALREAIVVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCN8</accession>
    <name>A0ABR3ZCN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003764</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF319">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="79"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="471" mass="50246" checksum="13C61777FBFC7548" modified="2025-10-08" version="1">MSDEKRTLPFDDSHHSADETTLDTNMEASRELDNNAANLDKDTEKAPDTANSADPEKDAAAAESPFAEFGPAPDGGWRAWSVAIGAGFITFAALGFANSFGVFQEYYITHQLSDKSADTIAWIGSCTAFFQFVAGSISGPLFDRYGSWLIRPATILCVFATMMISLCHEYYQFLLAQGILLGIATGMMQFPAMAAVMQFFDKKRAAALGVAVAGSSVGGVVFPIALSRMLNDPVVSSHLSFGWAVRIIGFVMLFSLGISCLTVRPRLPPRTTQFFVWSAFKQVNYISIVLAMFFLFMGLFTPLFFLPSYAVTQGMDTTLASYLLAIVNAASTFGRIIPGILADKLGRINVLAAGGVGTGIIILTLERAHTTAGLVVWAIAFGFASGTIVSGASAAISICTDDPRNMGTYLGMGLGAASIAVLIGPPINGQLLHHYSTYMPLTIFSGVMCLVGGFIAFSGKRDSKQGLFGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCX7</accession>
    <name>A0ABR3ZCX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003752</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22211">
        <property type="entry name" value="HkD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043936">
        <property type="entry name" value="HOOK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF28">
        <property type="entry name" value="GIRDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19047">
        <property type="entry name" value="HOOK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="638"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="200"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="540"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="783" mass="88484" checksum="CDF5CF69E10F3CB4" modified="2025-10-08" version="1">MPQQQQQPISRAGQAALLTWVNTFSLDRRVDRLEDLADAHVFAQMLHDLDPEYDPDELEQLNAGSSSAWLTNKRNIQSVFKALTKYIIHKDGSGAIDFLPRTIDVRAVSDNMNAEGIAQLVAIFTTAAMLGENNTRYIPVMRKNLTTSEQAEIMTILQRKDEERQRLVDSGVDASVDEATAALDPGLVAEAQLATLASDYDRLSKKLADTNTRLEHLQISYEVIKEDLERKERELDLERQRHGASESQLIKDLQEKLREQDDLISNQEGQAEDDRQTKQRLAQENSQLSRKAVLVEQLQDQVQELKHANDDLSKKANTIDRYKQKLEAQRGLEMRLEEALYEVGQNKEALKEFEALQRRNNQQQATIERFREMVSGLEQQIEDNRIQKTALEADIYAVHAQLESLKDQNQMSEVRIAELEQQLLQGTGSTLPTSPGGSKATFNLEEELQHTDDPASAYTLEIARLRAENNLLRSNVSVGSENDRLRADLEVSKTKEELARKKYNDIFEKHTLLEAQMQALASGATMSEGSPLWLEAQKKLQDTASELDRHKNVSRELENQVADKHREMLRLRADLGAVGKEGVDALEELKSTDALISESLKKELESLRTDFRSLQMDNEQQQKHLIEALVSKEELRKTMTTTDDKPLSPPTAATAASGEAEEQHRKTAEMNEKLRTAMKQLKKQYDIADQERTELQKKVKAAEAAGPAGSGSAGAMAAAYAAQRAAQDKIIKNLQRENAMITTAWYDLTSRLQSNHVVLQRRQDAPKSWLNKQRQLVNATPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD10</accession>
    <name>A0ABR3ZD10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003808</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="101"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="46015" checksum="79BF997F8ADC998C" modified="2025-10-08" version="1">MAIVSRAQPGEPLATSSTKAKPLQCSPPPFTKKLEFVIHMYSLQAVLSVPLWVRGWREYFYPPTGGPDIVKAYECRPTLPIRIFFPADYDQEATHTPLPTVMTIHGGGFCIGVNRDDDEYNRELANSQGVLVISLNYSKSPAVPFPTALHDLEALYHATLADESLPLARHSSATKSKIAVLGFSAGGNLALSLPQLPSIRESPDAPSAAISIYGCLDLSRDPAAKLRNRFYKPALPLPQGSRIDSLASLAPVFDWSYIPYGHDLTDPLLSPAYSSLADLPKHVYLVAAELDMLAHESWRLACRLGNEARRLQQKPTAGDREVPDPDSKVDRVKCVGKRASSKRKGVLDQDGDERYGWQETWAGGSVNWLLVPDAIHGFDNFNIRQVMGGEESMLDAELKTKAYVERIGAWLHNVVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDP2</accession>
    <name>A0ABR3ZDP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcriptional regulatory protein RXT2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039602">
        <property type="entry name" value="Rxt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013904">
        <property type="entry name" value="RXT2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08595">
        <property type="entry name" value="RXT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcriptional regulatory protein RXT2 N-terminal" evidence="2">
        <location>
            <begin position="37"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="424" mass="46439" checksum="6A82285F854D667B" modified="2025-10-08" version="1">MAARDQAIFLETVIGLQRALKRRSFDSDSDSDIDHSTNRGSKLKRRARFVRQGQLGAADGLTVLTETIEHAGYRREIISHNPPLIDDEGYEVDSDEDDDAAVQEAEAAAADQNPYAGIQLEHLLAPLTAVTDLPNHPTLSRPFTNKALTELATQGSNWMHKESAALWKVKPLLIKLCGDHIWVDSGLLVTPDDADLFDDDFVARLAAARESTAQPPAAPAGLLGEAGPSSSEQSDQNKEKEADPDADAAMPDAGDEADTADTAKAAATTEANGKSVAQPNGEGALIPRGGDEEMANADGDEEDEGFIHPLFLAPRSAHPEPNLGLPEAEAEDVRRLLQLWVQKQEEVSRGTKKLHEGLLRADRLRHTVLRWAKAEAHSGPNRDMSDGEDWYDQEEWGLDEDLKKGHDEEEEDQQLPNKKTRNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFA1</accession>
    <name>A0ABR3ZFA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPN8</name>
        <name evidence="6" type="ORF">Sste5346_003283</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="16"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="310"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="39978" checksum="1642115FFD8D847D" modified="2025-10-08" version="1">MPSTTAETLSLVTRNVSVAPLVLLSVVDHFNRSAATKTRNKRVVGVLLGQNDSKNVRVSNSFAVPFEEDDKDPSVWYLDHNYIEAMNDMFKKINAREKLIGWYHSGPKLRASDLEINELFKRYTPNPLLVIIDVQPKESGVPTDAYFAVEEIKDDGTTTAKTFVHTPSIIEAEEAEEIGVEHLLRDIRDVAVGTLSTRVTNQLQSLQGLHHRLGDIQTYLKKVLDGQLPVNHAILGNLQDVFNLLPNLSTKAASATGTPSTATTLGGGEGDLAYAMSIKTNDQLMAIYLSSLIRAITAFHDLIENKIQNRQQQEEKDAAKKEKEAAANGESSGPNGAAASGSKDGDKKDDKANGVNGDAKEDKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFD1</accession>
    <name>A0ABR3ZFD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome biogenesis protein RLP24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RLP24</name>
        <name evidence="6" type="ORF">Sste5346_002806</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF8">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="TRASH" evidence="5">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="210"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="241" mass="27937" checksum="14A2D27B72A17F30" modified="2025-10-08" version="1">MKRRRTIQEDTRSWKLTDLECRPTYPGKGIMFVRNDSKTFRFCRSKCHKNFKMKRNPRKLKWTKAFRKASGKEMVVDSTLLFAARRNVPVRYNRELAAKTLEAMDKIAEIRSRRERHFYKRRMAGNRKRELLAARKLVAEHSHLLLPRPQRPLHPKLRAAAAAKKLAALQEAGVDVELEDLEVDTTDGVKTKAAARRVVRQRITADGRVELAEEEVGNSSLVDEDAGDDDFDEEDDEMDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFI9</accession>
    <name>A0ABR3ZFI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7582 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056004">
        <property type="entry name" value="DUF7582"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24483">
        <property type="entry name" value="DUF7582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7582" evidence="2">
        <location>
            <begin position="224"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="760" mass="81846" checksum="57E63293D191D955" modified="2025-10-08" version="1">MPLKNLISSPLEAGQSVLDAHRLPSHLDAALEYTARRLARKALSIDLVVVRRDYQLPYSSAAPSPAESETFSQVSTDAPLRSVPLRPLPSLSTSSSSTTISSVSSPPASSGSFRFTSAIKSLVRSNTLPNLTPSHSASSSYTSSPAAVSPTLSSASFSSASTTSNANNGRTRGDGGRSSRWPFTPIRTLSSASTASSVPSTPATPATPATPATPATHFTSSSTSSSSQSSFGIRLVHADDLPQTHKRVLCHTLEKAARKFHLGPNWLAPSVDASALGLPFNLVQRSREQNQVLFATASTSALSSTPSLVLRSLDHLYTFKAALCSYAQSGDHYRLEDAVDELRRYILAQAHHGGSQRRRRQLLLKRELLRQYPTLSTFSETHLADVNRMYRRAYGGPELECGIETDGLSSSPPVVWNTLSTPVSDAPSTASKLPQLALDTKCAVSNTVVDGDEEQDTPTAASAENTAIPQTLAWTSFLNISPSDSPLMLPLLGATTERRNRFRRKMEEEEEKEEEEKLGEYEYDNASDVLSETSTTVSSLPSLSSSLLSVLSDEEELPTIRSPKSLSVVIEDSESAILGEVKSSVPEICTTNNTSPVIILRPTSTRPFGSLQTKAPLSPNKLLPVLTLQTTFASKPSKTTISLAHNDQKDDKEEEEEEQLTARPVANIRKNGGGSIFFGAASIGEMLQDAGEATVLVSPEEKIEPFRLPRFSRSSILLSPVVAGAPQPPKEYEDISPITRSEWGFLMGDQTGRQVTVTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFJ3</accession>
    <name>A0ABR3ZFJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Carboxypeptidase</fullName>
            <ecNumber evidence="12">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_002868</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008442">
        <property type="entry name" value="Propeptide_carboxypepY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05388">
        <property type="entry name" value="Carbpep_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045634637" description="Carboxypeptidase" evidence="13">
        <location>
            <begin position="16"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Propeptide carboxypeptidase Y" evidence="14">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF05388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1899470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="558" mass="61759" checksum="159017D5B57347DC" modified="2025-10-08" version="1">MRIAASAVLVGAASASILSPLGGQQHVLGDAAKKRLGSGDDAAAAVSPFATFKEAIKGLTVDTEALWEEVKLMVPDAFEKSTFFSNPKKHTRRPDNHWDHIVKGADIPKAFVTTAGGSKSHDSLEAYNLRVKAVDPSELGIDKVKQYSGYLDDEENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFFELGPSAIDENIKIVNNPMSWNANASVIFLDQPVNVGYSYSGQSVSNTVAAGKDVYALLTLFFKQFPQYAKQDFHIAGESYAGHYIPVFAHEILAHKDRNINLKSVLIGNGLTDPYTQYEQYRPMACGDGGWPAVLDESQCRAMDNALPRCQSLIEGCYKSESVWSCVPAAIYCNNAMLGPYQGTGRNVYDIRGPCKDSSNLCYPQMGWIAEYLNRDDVKKAVGAEVDNYDSCNFDINRNFLFQGDWMQPFHRLLPDVLAEIPVLIYAGDADFICNWLGNQAWAEALEWDGKDAFNKAPTKALKLAGSSSVADAFFKKEGYGTVKAAGNFSFMRIYEAGHMVPYDQPEASLDFLNRWLNGEWFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG77</accession>
    <name>A0ABR3ZG77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-lactate ferricytochrome c oxidoreductase</fullName>
            <ecNumber evidence="7">1.1.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLD1_2</name>
        <name evidence="7" type="ORF">Sste5346_003453</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF116">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE (CYTOCHROME) (AFU_ORTHOLOGUE AFUA_7G02560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="207"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="641" mass="68662" checksum="4605CB13D62C4E80" modified="2025-10-08" version="1">MLQHQLGRGASRALAASTTASARDVARCASSTPSLRRTFASKPPGNNTPTPSNPSSSSSNKPSQSTQQNRRNAAGTPNVDADGRSFRGQMLESIGARMAREKAEREKIAKERQDTASSRNAATTFMLLFVGVACYYLGTKIPQEPSSDSTLPLSATRAPRHRTSRAELEAAWADFVAIVGADNVSTAETDIAAHTSSDWSTHSAPEGTPHPFCVVYPSSTDHVSRLLKICHARRIPVIGFSGGTSLEGNFAPTRGGIVIDFARHMDQIITVHKEDLDAVVQPGLGWESLNETLAEQGLFFPPDPGPGAQIGGMIGTGCSGTNAYRYGTMRDWVLSLTVVLADGTVIKTRQRPRKSSAGYNLTQLIVGSEGTLGLVTEATLKLAVRPTDTSVAVAAFPNIRAAAACAARVVGEGVPVAAIEVLDDAQMKCINEAGSTSRHWAEVPTLMFKFAGSSARAVREQIDAVQAAAKATNSVSFDFAKNADEQAELWSARKEALWSAIATKQPGERVWTGDVAVPISRLPDAIEEAQADLRRVGLRGTIVGHVGDGNFHTIVVYAPEQRHTAEEFVHRMVKRAIELEGTVTGEHGVGLVKRDYLPHELGEDTVAVMRKMKAALDPLCLLNCDKVVRMQKPKAGEIAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGL6</accession>
    <name>A0ABR3ZGL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002687</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59503" checksum="8241AA6A1C34B9B1" modified="2025-10-08" version="1">MDIHRLIYTVAGVLLVILLRSVFRRPVIRRHGVPLPKPPNTLPLLGNGILFLQARQKLFAWFVKCQQQFGYETFQVAVPTLPPGVVINDPKNLEYIFKNEGTLISKGNFVKGMLWDLFGYGIVNADGDVWRTQRKAGLSFLSTANIRVLTDVALPKYLADTISHLREQAEVDDKTKATKEIDLQAVFHELTSRIMGRMAYNMEMHADDEFSKAFDYASGVTTERFQNPLWFITEAISGSAELLKSLAIVKAFGRRIVSTAVADRKKQHLVMHGIIPGPSSLSTPTPFSNDSLADSKINEVSGSLINSLLDAILDEEVVTDAALNYLSAGRDTVAQGLTWTFYTLMKHPEVVEKIRKEVQNVSPTGNGNKNLKYHSLTPVAMPYTMAVFYEGLRLFPPIPFEIKQVDPVGLTLPDGTQLERGSLIIWCSWALNRSRLTWGDDADEFRPERFLEPNGKRLVSRTAWEYPVFHGGPRTCLGKKMAESMAVQIMAAVAYFFDFELVDPTKERVTKTSLTLPMEGGLPCYVRARDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGP0</accession>
    <name>A0ABR3ZGP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxin/Ferlin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="65098" checksum="77A6AD0DB1DBD0FB" modified="2025-10-08" version="1">MPKIKSRSRRAPALKESDYDHEISLFDSAADDPAEINGVDGGDGAAPEIDVERTASPSPEPPSRNTAIDMVDGASDKATSRRPSGMSPTPNSGAALSPVVTATSATPLLNTLSTIPTAVEGAGSASRKPSRGRNPTRYGSISKIVAEPQDGAPSVQVEDATPDVEIPNPADRKGKQATTTATIVTEQPSRQSMQSVASAHSVRLEQEAAIDILYENERGGFLCGIPLFSRQALGNLDPSPWTNYAHGTSPTDITTAQVPDPSWEWAWPEWRVNREDDGFEDENGWEYSFMFAKCFSWHGPTWYSSFVRRRVWIRKRVRRKNSAAMSAAASAIGLGEIDSVTDPHLLNPEYFTVMSAAAMRRSSSRASSRHASRLSLAAQSMTPSSKSGAGEGASGCEGEENGHEGHDGGYIEMPKELVNADILMCFLRAARIDREKIEAVDNFIQFAGEDLVRLQDFMHEIMALFVFQASRRTLLTQLTKAHDEAVEARQKATEASEAAKSDKGKGAEAATAEILADDGHTDTVHKLQALGRRIGYLAAAVKHADEEVRRLEYWSDIKAMAQRGATNGAVGQGEWDSHQWQGVDRSGPMPPPPKSPTKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGS4</accession>
    <name>A0ABR3ZGS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOP16</name>
        <name evidence="9" type="ORF">Sste5346_002779</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="291" mass="32096" checksum="D9AEFD6211BD938C" modified="2025-10-08" version="1">MGRSVRQKRKARSSRPTVRQSNNRARPVNPTGNAIIAENWDKAQTLSQNYRRLGLMNRLKVTTGGIERLGTDVVKERAAANSKTDARIEHYIDPFNKTANEILGDKRQAPAKSSSSSSNVREVRVERDANGKIVRILGDAAPAHNPLNDLLNDLEDEEEEEEEEAAGKTYEEWGGIEEAPKTKSKKKLEKQAAAKAQAAASTSTATTPVVAALEQLASRPVGPKHIRHQSQAERAWLQTLVDHYGETNPSDSTLAAMAFDRRRNPFQRTANDIRRRLATFRAEGGAAGVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHL2</accession>
    <name>A0ABR3ZHL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002678</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF54">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045399023" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="198"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="670" mass="71581" checksum="01D80C0D07DD2AAF" modified="2025-10-08" version="1">MAPSLRVAALAAAAVFAPFASAQSLTVDNTTIPATADTVAPAAADVDATSSNSTVDLFSSETVQLTGNVIANLTALNLTSVDLFDFDDETTAATGSSSKCRRSTQCKVVPGNILYPISLVWDIFGLLLGPGALIKTVPLASPCYTNWGDQSASECAFLTNNWSNDSYIHADDPTSIMWPLYQGLTCMPTDTPSNKCTLGGFPSYAVSVSNVAQIQLAVNFARNANLRLVVKNTGHDFVGKSSGAGALSIWTHNLKQIQFFSNLKLNGYSGPAFKLGAGVQAFEMYQAADQYGVTVVGGEGKTVGVMGGYILGGGHSPMSSLYGMAADQVLSMEVVLPNGQFVTASSTSNPDLFWALRGGGGSTFGVVTSVTVKAYPKLQVSVSTFNIVSGGNVTADLFWDAMTAYFKYLPVFTDAGTYSYFDIIQIAPGTYYFAMAPFFAPKLSQAQLETLLAPLFADWAALGVPVNALEYFNYDNFYDGWNLHFPLESVGVATLKTASRLFPRANFEPATGNATLFNETVAAIRYVVEQGSTILAFNIAANPAGGYPDNAVNPAWRKTVLHAIQAISWDADADTATVAAACLKLTNDWQARWRATCPEAGAYMSEADILEPNFQQSFYGSDNYARLYAYKQKVDPWGLFYAPTAVGSEDWYITGQVEGIPTQNGQLCHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ5</accession>
    <name>A0ABR3ZHZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">clc1</name>
        <name evidence="9" type="ORF">Sste5346_002587</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="42"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="235" mass="25693" checksum="078985C74E36D9D8" modified="2025-10-08" version="1">MADRFPSLEDFDSGAQTDVKDTNIEASSDDFLARERAILGDDANQFTTPGDSAAFETSGGDDNLLGGDSAETAQFESSFPDLAAQEQTSSTTITGGPSVNFNSGYQATVEDEEEPEVIKAWREKRDEQNAKRAQQFAQQREETIAEAQRNIDDFYENYNNKRDKLVSATQKEAETFLNNRDDVTSGGTSWERIAKIVDVSGKGAKGGAAGSGKERFRELLMSLRKDEKAPGAEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ54</accession>
    <name>A0ABR3ZJ54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7 9">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_002538</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8 9">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7 9"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="11">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="8">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="37523" checksum="21173A71103799A8" modified="2025-10-08" version="1">MSGGWNTIESDAGVFTYLLENLGVKDVQFEELLSLDAQALAELNPVYGVIFLFKFPTNTPYVGDGGAPRDGKFDHAASENIFFAHQTIQNACGTQALLSVLLNKSAAVGGNVDIGQHLRDFGEFAMALPPDLRGEALSNDELIRDVHNSFAKSSPFVDETQRPSNPDDAEDVFHFIAYTAINGRLYELDGLQPAPIDHGACDQNNTVEFAERALEAVQRRIARYGADEIHFNLMAAVRDRRLQARELGDTELLAREARKRRDWQFENALRRHNFVGFAHEVLEGVVEGKLKEGEAKGEGDAAYQKWVGDATTRFEKRMQDKQRRRHPQGDDVEMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJM6</accession>
    <name>A0ABR3ZJM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CHC1</name>
        <name evidence="10" type="ORF">Sste5346_002317</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015348">
        <property type="entry name" value="Clathrin_H-chain_linker_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09268">
        <property type="entry name" value="Clathrin-link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clathrin heavy chain linker core motif" evidence="9">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="540"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="692"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="840"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="986"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1135"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1281"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1430"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1610"/>
            <end position="1640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1685" mass="190147" checksum="985E9E2961DCF0D6" modified="2025-10-08" version="1">MAPLPIKLGEIVQLTSIGIDSQAIGFNSCTLESDRYVCVREKKNEAASPEVVIVDLQNLSNVMRRGIKADSAIMHWSRPVIALRAQSRTLQIFDLEKKAKLNSATTNEDVVYWKWISEATIGLVTETGVHHWDVFESNKAPVEVFKRNAAMSACQIINYRIDADSKWMAVVGISQQQGRVVGSIQLYSKERGVSQAIEGHAASFATYQMDGAPQISKLFVFAVRTASAAKLHIVEIDKPDANPAFPKKAVDVYFPAEAVNDFPVAVQVSQKYGIIYLITKYGFIHLYDIETGTCIFMNRMSSETIFVSCIDSESTGVVGINRKGQTLSVKVDETTIIPYLLQNPANTELAIKIASRGDLPGAEQLYGRQFEQLFNAGNYVEAARVAANSPQGFLRTSETIEKFKRLPQQPGQMSYILQYFGLLLDKGGLNMTETLELAQPVVAQKRTELLEKWAKEDKLFASEQLGDMVRPLDLALALRIYLKANVPHKVVASLAQANRFNEIIPYATKAGYTPDYMQLLQHVARANPDKAVEFATMLANNEGGPLIDLERAVDVFQSQSLLPQVTAFLIDALKENRPEQAHLQTRLLEMNLLNAPQVADAILSNQMFTHFDKAHIAKLCEQAGLFRWALDLYEDPAAVKRVVINVPGTADFDPEWLTTFFGKLSVEQSLDCLDAMMKHNIRQNLQSVVQIATKYSDLLGPQNLVDLFEKYKTSEGLYYYLGSIVNLSEDPEVHFKYIEAATKMGQFQEVERICRESNHYNAEKVKNFLKEAKLQDQLPLIIVCDRFNLVHDLILFLYQNQQFQSIEAYVQRINPSRTPAVIGGLLDVDCDENIIKNLLASVQPGPIPIDQLVSEVESRNRLKLLLPFLESALAAGNHDQAIYNALAKIYIDSNNNPEKFLKENDQYDTLSVGKYCEKRDPNLAYIAYSKGQNDLELVNVTNENSMYRAQARYLLERADRELWGFVLSENNIHRRSVIDQVISTAVPECTDPTKVSEAVACFLKADLPAELIELLEKIVLEPSPFSDNQSLQNLLLFTATTADKARVMDYIHKLDAFDPQEISAACINVGLYEEAFEIFKKINDSASAVNVLVEHVVSIDRAQAYAEEVDTPEVWSRVAKAQLDGLRVSDSIDSYIKAQDPKNYEEVIETATHAGKNEELVKYLLMSRKTLREPAIDTALAFCYARLDNLPELEDFLRGTNVANIEESGDKAYAEGLFEAAKIFFSSISNWAKLATTLVHLGDYQAAVEAARKANNIKVWREVHEACVEKKEFRLALICGLNLIIDADQLQQLVKQYERNGYFDELINLLEQGLGLERAHMAMFTELGIALSRYTPDRLMEHLKLFWSRMNLPKMIRACEEANLWPELIFCYYHYDEFDNAALAVIERPENSWEHQQFKEIVVKVANLEIYYKAINFYLEQHPSLITDLLQVLTPRIDVNRVVRMFQKSDNLPLIKPFLLNVQSQNKRAVNDAINDLLIEEEDYKTLRDSVENYDNYDPVDLASRLEKHDLVFFRQIAANIYRKNKRWEKSIALSKQDKLWKDAVETAAISGKSEVVEELLRYFVDTGNRECYVGMLYACHELIRPDVVLELSWRHGLTDFTMPYLINLLAQQTKELAVLKADNEERKAKEKEQEKVEDNTPILGGNRLMITAGPTGAGGSVGRASPAPFAGANGFAPQPTGFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJV7</accession>
    <name>A0ABR3ZJV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002062</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="526" mass="59487" checksum="80EB7B7DB8129CBA" modified="2025-10-08" version="1">MSTLNIITQQLQLAVAQPLIVAASAVGLIVVWYLYSYFTSPLRKFPGPFLAGWTNLWRLYHANSGKYQWTIEALHNKYGPIVRIGPNLLDLDYPEMIKTVYGTDGKWRKTEFYHNSSAYIDGKLTYHLFSTTDQAAHARMKRPIVKYYSMSSVLAMEPCVNRVLNDLCTHLETRFMDKAGRASADCDLGRWIAYYTWDFISAATFSKRFGYMEKGYDFDGTIHIADQVTDYMAAVGQMPWLDFVFDKNPIKRIGPPNLQNVTRISYENMVARIQEGDEKADAKTAEEKDFLDHFLDAKRKVPDVVDTNVVMGYLQVNMLAGADTTAITLRAIFNYLISNPRTLACLEKEIAEANLPLVDGVVTFATARALPYLDAVVREAMRMHPGVGLLLERYVPADGATLPDGSFLPPGTGVGLNPYVIGRNKSVWGDDSAEYRPERWLQRADESDDAFKERLRHMNASDLTFGGGSRICIGRHVAMLETYKVVATLVKKYRILPANEPKEFEIVSTWFPRQSGLVSRLEKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK82</accession>
    <name>A0ABR3ZK82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="60117" checksum="01D4D0F99AAA09E9" modified="2025-10-08" version="1">MAVTYENPDSQTISPVRVVISQVVAIWSAHWTVLLPLLFVSRLLYKRYASPLRRYPGPWLASVSRLWKVISTASTNTQWQHIDLHRKYGRVVRIAPDEVSIASPEAARLVLSAGKHFYKTDFYGVFPPPENPDIFTEVREHVHAQKKKVANVPYSMAAMQQLSPFINDAVELLVSKLETLAGGQANDAKGPQVDLGAWLHYFAFDVLGEVAFSRSFGFLEEGRDVENAIKTIDDSQRYNGIVGQVPELDYILRRNPLWKFIPALDTKNALITRMALEELGRRKPFDKESEGKWRGGDGRQDLLASLIKGHLKDPEKFAEGDVFAVAHGAIFAGSDSTASTMQSFFWQVLHDRRIYEKLINEVDTAVADGTIPPTGNVSWTEGQNLPYFQACLRESMRVRPAVGLNITRLVPPEGAELDGIFFPGGTRVAVNGWVIHRDRATFGEDADEFRPERWTEDEERARRMDRYMVQFGGGAHVCIGRNLALLEINKVLPRLLRDFRFSLVHPDRTLNAHATFFVVQEGLDVYIEKKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKV9</accession>
    <name>A0ABR3ZKV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="68"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="23586" checksum="C1856AF315F3530A" modified="2025-10-08" version="1">MWTTTVIDISTNVQKSDWFLRLNPNGRIPVLLDNVQSPPLPVMETSAELLYLARQVDTRNVFSFAENDTASYSEALQWLFFWHGSGAPYHGQVIHFAILAKEKLPYAITRFTNELLRVFGVLEIRLSGKYIGQPREYLAGPGAGKYSVADMGTWPWIKLWMFTGITEEQMSEFPHLRQWLDRIEGRTAVQRAMGDKYKKVDDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL50</accession>
    <name>A0ABR3ZL50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1168 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="24523" checksum="468A4E630CB8D8AC" modified="2025-10-08" version="1">MSGEGPESIPTSADRRSKRPVKKRALTPVSAQAAGLDALFAKPDQTIKVPVSADVARLRGSGGGAPPEIISSVQGSSSGAGSGEFHVYKASRRREYARLRELDEEAARDKDAEEFEKEKREREARDDEKTKRNREKREKAKARKAKGGKKNGGGGGGGAQAATATAAPTKPVLPKFGRDDDDDDTKDDTAQASGDESTSKANGTNGQTRKPAAQEPIPVAEGPGLLIQDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLZ4</accession>
    <name>A0ABR3ZLZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="26"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="233" mass="26131" checksum="7A829BB6F12E5F28" modified="2025-10-08" version="1">MSLRAAIAPETYDERLAWYQENCLAGTAQWLFDNRNFHRWADLTKGVVPSRWIYLHGIPGSGKSHVAAAAVDHIRLKMKVESHSRPVLYGLINHTSKLGLTTLSVLKALLFQVVEDDPDLQCFLIQSKMSDLRGSVTRITELLEATLLPMSGAEYSVPSYIVVDGIDEMEETERLQLLRQLCVIADACANLRIMVSSREEHDIAATAKKQKAKAICVNANNEHSIEAYVNHRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMS8</accession>
    <name>A0ABR3ZMS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_001704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331:SF1">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="205" mass="21997" checksum="7D04FFE65DC59F7B" modified="2025-10-08" version="1">MFRRSFSSALSINPHIKAYRLATLPPSYLLSYLDTPTPSAATAVGTTTELPPTPRSFVANDRFMDILNDVLRENAAQDDGLRAQAVAFAAPGGTIFSNAGASHTGSSGSVQRGGSGGGGVGGWVHLSDLRNPPDFGRIAWPEDIFGSIEVDSTGKLLDNFQVSGSYRILTNEGILGLSDFLREKLVQRLKEEDKNDTSDRPQILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMW1</accession>
    <name>A0ABR3ZMW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="437" mass="44205" checksum="1C48073019F744AA" modified="2025-10-08" version="1">MAGGNLPQAALEWAHQFMFPHGPPPPLPPPPPPPPPHHMQQQQHPQQQQQQQQSPHPQLLLTGPGGGGHHLQESPRQDPQQQHPTTQPPPPPPSLPPQQQQHRPQSPYGQVQYGPGGREGGGPGSGGGGPGPGPSQGGAFMPPNPPSPTRQRGFTLPANSGRPERGPAPPAGAGGGPSNLPTLNTNVAHGTFGQQQLDLQASPPILFHHWQPPGVGGGSGGGGGSGGGSGGGTGGSGSGLREATAPVSESPKKRKATGPQQAPPPPSSHQRYRSPPFAQSQSSGSLGNPPASRRNRGHARQRSDMSSYRGPGRGGYGSGGGGGGGGGGSGGHSRGMSPSPYSSAPPSATGSLREGEEGGGPNRQQQQPSQPRSGGGHTVSSLLSEDVPSSGGPYSQGHRDALDRSSRGGSERRRSPHRQSDEKRRGSATGGHGEGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN39</accession>
    <name>A0ABR3ZN39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="18003" checksum="5D5CBE72A855AE13" modified="2025-10-08" version="1">MASNGSGSIPKEAEKAVEEIKKSSLTEKFSAWGSSSIPPMGLATLIIALHARPLQPFPLLFAPALMFASYVNVAGYVIDAAGMTAAWSGMYVLLSLRRRRGAGIISRAWTPASLRTSTQRLNTPARRAVSAAAIGLGSINTVAGGLVYGITGDRVKEAQEREERNRWGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNR8</accession>
    <name>A0ABR3ZNR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 4</fullName>
            <ecNumber evidence="6">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC4</name>
        <name evidence="6" type="ORF">Sste5346_001328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="147" mass="16482" checksum="41AEA7925B66837C" modified="2025-10-08" version="1">MALKRINKELTDLGRDPPSSCSAGPVGEDLFHWQATIMGPSDSPYSGGVFFLAIHFPTDYPFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRAKYEATAREWTRKYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNZ9</accession>
    <name>A0ABR3ZNZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21715" checksum="5A640237EC09EEE7" modified="2025-10-08" version="1">MHIRPSAKSDNYLNLCLEQAELSPLNFWPGAIVVKGGKVLGAGFNDHRPGYDGGNVYAGTSAPLSMHSDMMAINMALGGQAAGMRNIKANRGTKHGGTKQRRKAVEEYVEAILRASIPSGGISSDKKNSRPSLTEMAEDTERGTRRRRWNTRLADADLYVARLAKPNTCNQGKMSSVDACGVAAILFTTGVVTDVACAATMVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP08</accession>
    <name>A0ABR3ZP08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="6">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="616"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="654" mass="72664" checksum="430EBAD1098CF109" modified="2025-10-08" version="1">MAVLLSALSLRRKTRFLVTVAAAFLFIIYVFQPRAGRIYLHKVLQPARSSSDPIFYVNSSVNWAKRPRLHPIPDADLVRLPTGTPEPMPSIQYNFRADPDYKAADNKLLRDTRRDAIRDAFLRAWNSYRENAWGYDELLPIKLKGKDGFSGWGATLVDGLDTLWIMGLRNEFDEAVRAIATIDWDAATGYECSLFETNIRYLGGLLSAYEMSGATPLLDKAAELAHMLLAAFDTVSHMPSNRFHFDRAWQGLLVPSDHEASAAVGTLSLEFTKLAQLTGDNRFYDAIDRIKRELARVQDTTTIPGLWPTFLDIQNGFTAKGHMYTLGGMADSLYEYLPKMHLLLGGQDATYRDMYTKAADAARQHLLFRPMIPDPDARGHDILVSGTVLAGGGPRSGINLVPEGQHLTCFAGGMFALGGKLFDRPADVDVGRKLTQGCIWAYDSFPTGVMPEAFDLVPCPKPSGWLDKMALGLTNKIPAENTTACPWDEHAWHAAQIPKDKRCPPGFASIRDSRYLLRPEAVESVFLLYRITGDRSLQEAAWSMYLNIERSTATKHANSAIADVTVTGSPQKLDSMESFWFAETLKYLYLTFTEPEYYSLDDYVFNTEAHPFKIPKPEVPKTKASPPAADGKVIAKTHQSSGRTAGKATNKATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ47</accession>
    <name>A0ABR3ZQ47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="351" mass="35695" checksum="33CFB9AA47D18465" modified="2025-10-08" version="1">MTSTRTNLGPLTTAFTYPASCTNNVIQCSTCAFAWQAQTCSNNPNNAAGVQDNANCWPPRQTSSSLTTGVALNGWGVYSPGLSCPVGYNTACSATGTTIGGFQFQFPVSADETGIGCCPSGYTCSYGGSGSYQTCFSVATTGSFSAVQCSAGSSIDLSYYTLGTTATITTTGTTTVSASGTGSETAHAVTNTGVDLVSFNSATLLAPMFQLVHRAGDLPSSGTSGAATENTSPAHTTGAGVSDSGSNGLSSGAIAGIAVGAVVVGLALVGAFVYLFLKQRKQKRMIAQYAPPPNMSGNMGMSPHDGMSPHGMQDGSYFNGATPLSMKSNMVPQPSPVYEAPTESHQRHELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQI8</accession>
    <name>A0ABR3ZQI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chromatin remodeling complex Adenosinetriphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ISW2</name>
        <name evidence="11" type="ORF">Sste5346_000870</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="192"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="488"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="10">
        <location>
            <begin position="857"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="816"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1035"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1086"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1139" mass="129824" checksum="461C8D8CC6570242" modified="2025-10-08" version="1">MPAPRHDDGNDTDASMPDAPISRYEAPADDTPDYTEDSDTNPNTTASSVMGDPLPENRKRKSEANQLRRSIFGRKHDRLGESKEDDTIRRFKYLLGLTDLFRHFIDTNPNPKVREVVAEIDRQNAEASKSKKSARQGGAATGRQRRTEAEEDAELLQDEKHGGSAETVFRESPAFIQGQMRDYQVAGLNWLISLHENGISGILADEMGLGKTLQTISFLGYLRHIMGITGPHLVIVPKSTLDNWKREFAKWTPEVNVLVLQGAKEERNNLINDRLIDENFDVCVTSYEMILREKAHLKKFAWEYIIIDEAHRIKNEESSLAQVIRLFNSRNRLLITGTPLQNNLHELWALLNFLLPDVFGDSEAFDQWFSGQGRDQDTVVQQLHRVLRPFLLRRVKSDVEKSLLPKKEVNVYIGMSDMQVKWYQKILEKDIDAVNGAGGKRESKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLVFNAGKMVVLDKLLKRMQKQGSRVLIFSQMSRQLDILEDYCVFRDYQYCRIDGNTAHEDRIAAIDEYNKPGSEKFVFLLTTRAGGLGINLTTADIVVLYDSDWNPQADLQAMDRAHRIGQTKQVYVYRFITDNAIEEKVLERAAQKLRLDQLVIQQGRAQIAAKAAANKDELLSMIQHGAEKVFNTKGGGTGTMGEKGMEMSDEDIDAILQSGETRTKELNARYEKLGIDDLQKFTSESAYDWNGENFAAKKKDVGLTWINPAKRERKEQVYSIDQYYRQAMYGHVQAQKEAKPKAPRAPKQIHIQDYQFYPEALRDLQDRETACYRKEIGYKVPLADGEEETLSEREAEQQIDQQEIDNATPLTEEEQEEKQRLSTMGFGDWNRRDYQQFINGSAKFGRTDYENIATEVDSKTGAEVKQYAKVFWQRYKEIGDYPRAIKVIEDGEEKLRKIEHQRKMLRKKMQQYRVPLQQLRINYSVSTTNKKVYTEEEDRFLLVQLDKHGVDSEGIYEKIRDEIRGSPLFRFDWFFLSRTPSELSRRCTTLLTTIVKEFDDLNTTKTNGHGHANGKPKREPEDEENDEDSVLGAPPKKKSKNGVKNKPLDNVKAKNGSSSKASSASPSRASSVASSSANKKGGKPQGKAVPAAAAASSKNKSKGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQN4</accession>
    <name>A0ABR3ZQN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000999</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="406"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="709"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="719"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="755" mass="84733" checksum="B95678EAE1E8C776" modified="2025-10-08" version="1">MFMCRACARRWRGPPTAMFAVPGAVRQAQRRPIASSFSQSSSFSTTPLVSTAAIRSTIDARPLQSRQKHTGRTPGPAKISKEKEDDLDEDLDEDPSDYVSGSGKNKIHKSAKDSKDTIAVAALSNEDDKADANLLRRAKQRLRYLNDAYTIAESTGTLLKKNEYDEAVTMVRLASKKDSVVVSWNLLIGHLMRQDKLAAAIKLYNEMKKRAQMPNAQTYTIIFSGCAHSRHADQAVHHATRLYHSMMTNERFPPNKIHMNAVLNVCSRARDIDSMFSIAATANKKERAPDCVTYGTILNGLRYVTAQPHHRPNEPGNAGGGSSGNRNGEDEDGVNDVYIDKEQARTSVARARAVWSEVVSNWHGGVMMVDEKLVACMGRVLLLGDHNDNDDILSLVEQTVGLERLDRTPPGQIAAPKKDAKDEEVNDEKDAKAETATGDKPTITAVQTSPPRETQFDRRDKRAGLVKPGNNILSVVMSSLGTTKKTTLAMPYWEALTGPKYGVVPDSENYYRLLKTLRRGRASKKTVEILEKMPRPFLVPKTFQLAMATCAADNLNDHVFESAGKVLDLMVRTLNDPDPYTMRLYLQTTMTNNRRFRKETDPSKREAAKYAFGRQIVRALSRLWDPFRRAGNVLSYPAKPFRSPEEQHKETYNERRELMALARQMVSAADMVVTERMVTDEAVIRDLSGSRNLLNRQITRFYEKREVFEPKLKKAKRGPRNEKGRRWDAGDNKPKPKENQKPKGDNNGTVDAAWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQZ2</accession>
    <name>A0ABR3ZQZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotide exchange factor sil1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SIL1</name>
        <name evidence="3" type="ORF">Sste5346_001629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185408" evidence="2">
        <location>
            <begin position="37"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="52144" checksum="EF71E13F1C724D75" modified="2025-10-08" version="1">MARPRSRSRPVASRPLLGKFLAVLFVVTCLLAMASAASSAQPSPRQEKDKAGSRSAAASSDDLICHTDVVAECYPRVFQPTHEFQRVHEDQDLPPGLHVRLNINTGLREAKINNESEELPEGLQGLPVDSSVVLVDQPEGANDIEVDAPVARIPKGAPAYDPAGVVKDPGAHADGEGSPASITFHESIALVKGVAVGQVVGHDADGKIGLAVAEQARFIDALVEIDDVAHDIYYGLKLTEDRVITRQLLCLMSGGSIGGGSIFSGAGHSGSGKGLEAAQKAAMAVASAVQNNPVALRELSTYWDMYKSGLCATAGGQVTTLGDVIFGPYHHATEDVPEHRQEGHDNNYIAANHPAWIRSRLLAISGLIKDKDIMQDFLSRGGLTEVLKLLVDHEGDAAYDAVRQRAANLVNDNFLDESMGADLSLWPVKEFAAAVAEKPCDGTVHAFCWDYHIQQLAKAHKKDKTHWSHGLLKGLHEVKKGGSGKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY1</accession>
    <name>A0ABR3ZRY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="73355" checksum="450D0B8CC254DD2F" modified="2025-10-08" version="1">MVCYECRSRLLSGPALRAFPSLDHLRGYSHNRSIPNRRQTIHAVREAFSASAKNFVIEFGDDAAHVAYNLTEDHIKELLDLENNVRLPSHPVRWINIWNPSDQKGIVEAIGSRYHFSKRLTMSIWAWDRVKKKILDEKQAARKQQKNDLRQNSHHLHHHHSPSGTGLRYRFWSKIRPKSPALARSIADPEDGIVVDPIASKIPGVAGGGQFDGSHGSMPVDDGPDGQQQAAPIDAMIKNNIPAFRIMQESLHYTTIDQEQHFVCIGANWLHQRLKGQTQPNMSLVPPKHWSWFVVCDDHTIISFHEEAYYEKAPKSVDKQKWEEEELGHMRSNTLKVFRQLSKVGIKEDQHKFSQLTSVRQTGGGRRLGDNKAQSVDVTSNLFYYLFEDYTAAFDILNSSKAVLDEISGVILGTAVWKNREDTSNVVPRLYKLNKEMRQLQHLFSNYKTLIDRLLSSNANGFDVTGSSFYFNDERDINSLNANSDSRLLSTKAVNRFKRLQIQLQSLMLDAIKDCLDEKESLQSTYFHLITQKDSHSTERLTRSATLLAKLSVFFLPISFMTSYFSIQIPDLIDGYTAWTYWGAFAVIASVSFLSLFFFSKVLMFLSERLDHWADGATQWTSERAGLKKRKALRAMEAEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS58</accession>
    <name>A0ABR3ZS58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ADE4</name>
        <name evidence="10" type="ORF">Sste5346_000140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="59850" checksum="7BE825E57C5B81C8" modified="2025-10-08" version="1">MCGISAILLGDSKADSAAAELHESLFYLQHRGQDAAGIAVCQGGRVSQCKGLGMASKVFDEGRRVSTAALPGFMGISHVRYPTAGTTSAAEAQPFFVNSPYGLSMSVNGNLVNTPDLVTFLDYEARRHVNTDSDSELLLNIFAHALGELGKARANVDDVFSALREVYARCIGAFACTAMLAGFGILGFRDQNGIRPLCMGSRPSETLEGATDYFLASESIALVQLGFKNIVDILPGQAVFIKKGEAPRFAQIVAPKSYTPDLFEYLYLARADSCIDGISVHRSRQNMGVKLAKRMREVLSEDVIKDIDVVIPIPETSNTAAATLAEALQKPFSNGFVKNRYVYRTFILPGQKARQKSVRRKLSPIASEFKDKVVCLVDDSIVRGTTSREIVQMVKECEAKRIILVSCSPEITHPHVHGIDLADPAQLLAHGRSLQDMTDLIKCDALVFQTLEDLKEACIEAVDSTSKVTDFEVGVFCGNYKTPVPDNYFERLNIIHTTGKKPAAGSVTTNGDGAFLVASSGPVNGVRHQENDEGSEYREDISLYNNFSGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS88</accession>
    <name>A0ABR3ZS88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="275" mass="29766" checksum="14E76DA655F70BB7" modified="2025-10-08" version="1">MASPCVACNEPLVFPNEDGVEVPDDLQLTCGCHFHWQVPFPALSPKNLRVVAPAVASTLKCPSCGQNVASSSQVGAGSSSSAAAASETHQILTRYINESGLQEGYDIYSDIAEEAYYSTYPQFLRARPFLAMCSEGHVEGIIELCQEADTEEEDGDDDDEMEDDDGPSVPAVRSAALLRYQDPLNQMATGLHVAIANDQINVAYLLLYLSSHLPMDQFPPDLLQFAAQIGRPEQAILENADIRSLQTAQGETAEVLALRKGGLWAEMAQRGLFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSL2</accession>
    <name>A0ABR3ZSL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="715"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="762" mass="80695" checksum="5361A2C25E8CD48F" modified="2025-10-08" version="1">MDAMYINSKAHVLLSEDKTRDGARESRERSSRQRPASDAGLSSGRAAVKSVSASSTSASAYPRPHAYRHSRISSSSSYSATVTISSPVAALTSYQPRASTSLSALSSQNPSSSLPPPPPLPPQSRPVNGHHRNGSVSSNGNQVVPNPPSSSSILFFNPGNNTTPETSLVGARGKSIPLDDSTAAHRTSALRELNSSFPSPVLRHQQAKSTGAQSTTYSQPVIVRTYSGPPQSPSTSAHYRPPSSSRRAGSRASYARRIPYVPSGTASSSTWDPAANSSNDAQRVGWGLANSLFGMARSKRKKGGFLPWPFVASTDGQSQKDEAKLPPIEAFSYRGFMADLQTTTDIRSDLDRIAEICARSRYCLSDKYDSHVTPHGSGASFMASVSQHPNHSKGRRKGASSPGGPTLQAVPSDDDESSARGHRRRRGGIGGARRRSAAYGTLETIMSSSRSSEEDKTKKKSAADIAEAVRGRAARKGLAATDSPGDGTTTTTEENSVLDQTSSKSSKSPNGKDNGRKGSKSPQNSPRASLVDDDNNAPDSNGQPTTSRSSPDRQQEKIPRRPKSTSFAHAVIGSSRQQQKHRHTAGRERTSTPTASTQRGLSSVPTLLSDPALPQTSDGTIDMYNVLDTVNGQSLPQASNSRRSRNNREPSIHIVDPDSEAGQDPSLYLSPEDAAEAGFFSGLTNWIPWMAPGNDGATIGQPYPGGHHASRSRQPATQTTAVAPAAAGPSHAEGSLRELLKTVDDTNGKEKKGKAVDDSGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSM5</accession>
    <name>A0ABR3ZSM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">QCR7</name>
        <name evidence="10" type="ORF">Sste5346_000509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000022">
        <property type="entry name" value="Bc1_14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="14576" checksum="ED6106BFEA32A58C" modified="2025-10-08" version="1">MSYLTLAPFIRSQPWLHNLLKPVANWYTSLAGYRQLGLRADDLIPEENDVVQQAIGRLPAQVNYDRVYRMRRAVQLSLQHKLLPKDQWTKPEEDTPYLLPLIKQIEAEIKERNELDTIEIIKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT80</accession>
    <name>A0ABR3ZT80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="232" mass="24488" checksum="F3EAB82B0420DA78" modified="2025-10-08" version="1">MTRVTAPMSKLTRSLGSHPSVARPAYIAGSASHQTNASSGAGRTELGDRDDNSRRFTMTHRPTPQPVPSRNRIVPLMQTFNFRTTTPRDARRDVSTIDYAVMPSFAGEADRAAGSAASRMALRVPLLPDNFSPDRQNLDGHAPEVADGPLAGPQIVVVAAHPENIVAASALTEIEGMGIDGVELKFAHLGEESSSGSSSSSSKEASEPGMIRDLWKGLLDDLSGSSAVPKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTF9</accession>
    <name>A0ABR3ZTF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000042</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="207"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="318" mass="35174" checksum="893E4A8F4288367C" modified="2025-10-08" version="1">MAFNGRRGPNISQFLRELHENPTLVENDPAFSMDDQDLSMFTNTEFFDLETGQNTDFQPQHNPHHPPKPGSESNSASSTVSPLSEDTMTTMADFTHMDFMTTGDFNFPDFGATYSSPTIPSYQDNLGNLHQPIQTGPPSVYSASSSVSHPHARSHHNPSYASTAPTPPRIAAAAEKRKADVLSHNPQQQAPRGAVSFEDQTRVAAEEDKRRRNTAASARFRIKKKQREQALEKSAKEMNDKVHALDNRIQQLETENKWLKSIVLEKNAGNEEFLGKLLEDFKSKHASGASSRSGTEAESETAVAVVSDEENETRDSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTM9</accession>
    <name>A0ABR3ZTM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="11"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="56442" checksum="859DB28A4462A923" modified="2025-10-08" version="1">MAKITAFNLVSVFFAASGGFTYGFGFGVFTSSIGQPGFFSYFNLVKGSTYEANIIDAINSLFAFGAALGALTQGYTSDWLGRRRAIFAAAIMCIIGGALTAGSAAIPMLIIVRFFQGIGLGQCVTLAPLYISEIAPARRRGLLIGVFSAALGTGYTVVAWISFGTHYATNETVQWRVPLALACVAPLAQAIGVWFIPESPRWLVLKDRKEDAWQIVRRLHRDPNDAEERNAQAEFTQICRQVAYDKQFDVSYWQMFRRPSWRKRSFLVLFLMFASQSTGVLGIGNFAILIYESLGFTGGLPIMMNAVYTLIGTSATFLGSYLADRVGRRTLLVIGFPINAMFLLGEALLQRQYVDGTGASSHAGLSACVLFLFLYIVSYDICIDPVSFIYVAEVWPTAVRSKGIALGWFAYFMGTLTYTTLAALAFKNISWRYYMVFFGCNIVSSIAIYFFLPETKGKTLEEMGDLFGDEVVVHMADDGRGFVETGGDLMESKVAADGEVVMQEVVDTEREGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGJ7</accession>
    <name>A0ABR3YGJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046031461" evidence="3">
        <location>
            <begin position="22"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="210" mass="22755" checksum="D452B73F2640FE91" modified="2025-10-08" version="1">MRLHPLPWLLAQWIAPALVFGQTPQSIRDCPLPCNFVNGTSWLPYSRVSDLDWCNQTVLFQVMLHQPLDDPDIGSIVQACAASSSSSLSSVLDVLTGLTSGLTNDTASDKALFKRKSLNASAINNENSVTTFAAGATCMNHVETPTKAQRELQLLWSFSETGTSSKSVGDGMDNIRASAEHLAQFLSHDLSYMSSIMFAKINNVTMGVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL2</accession>
    <name>A0ABR3YHL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000133">
        <property type="protein sequence ID" value="KAL1887246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF33">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26064" checksum="A2B6BDEAC01F7986" modified="2025-10-08" version="1">MTSYTITPADLTVLRGKTILITGGVSGIGRAAVDIALEHGVNVAIGDWNDRLGTELAEKHKDRVLFRKCDVSNWDDVLNLFQATTIRFGTIHSVLSNAGVNTHEDLLDETFTDDGKLAAPSLKSIDINLVGQLYVVRCAMHYFTKWPETACQIVLTSSAGAFFPAPPIYMYCAAKAGVVAVMRGLRSEVVKRNVTINTVAPWLTKGAGMALFLPIVQPWMGEQLCQNVRKGQDILLGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHZ2</accession>
    <name>A0ABR3YHZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_009997</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421262" description="xylan 1,4-beta-xylosidase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="13">
        <location>
            <begin position="744"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1887759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="836" mass="88822" checksum="6B9BF00CA6F49CEE" modified="2025-10-08" version="1">MPSFSTALLLAGAAASPAAAALLSFPDCVNGPLANNTVCNTKASPSARAAALVKAMTIDEKLVNLVNTSPGAPRLGLPPYEWWSEALHGVAGSPGVTFNRNNGNNADFAYATSFASPITLSAAFDDDLVERVATIVSTEARAFSNAGRAGLDFWTPNINPYKDPRWGRGAETPGEDPFRIKGYVRSLLRGLEGPYVGGGNHNASAAPLSGPGNHGHGGNRTRSAIRKVIATCKHFAAYDLERWNGTVRYGFDAIVSLQDLSEYYLPAFQQCARDSHVGSIMCSYNAVNGTPACASTYLMTDILREHWGWTDDHQYVTSDCNAVLDFDHEHAYTKDGATAAAAAYSAGTDTVCEVPSYTGTDVAGAYNQSLLSEAVLDRALTRLYEGLVRVGYFDPADASPYRSLGWKDVDTPAARSLAKQSAADGLVLKKNDGLLPLSVENKTVALIGHWADATRMLLGGYSGTPPYYNNPAAAAAARNWSTVVFGRSAGAPISNLPHGTPDSWTRPALELARKADIILYFGGTDLSIAAEDKDRDEITLPGVQLNLVRALSELGKPLVVVQLGDQTDDTPLLKNSNVSAILWAGYPGQDGGNAVLDVITGVKAPAGRLPVTQYPGNYTSAVPMTDMALRPAVSNTSSSWNTSTSAANPGRTYRWFNKAVLPFGHGLHYTTFAANFTRLVPSAARGRNSSVPTTLKANNTFNIADVVGRCVHQGSAAGVRHKDLCHFSNVDTSVTNTGNVTSDFVALAFLSGNYGPAPFPLKTLAAYRRIRNIAPGKTATTSLSLSLSNLARTDAQGNLVLYPGEYTLLLDEPTQSTLNFVLTGDAVVLDEFPQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI28</accession>
    <name>A0ABR3YI28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41423" checksum="88A1ADB3541CD843" modified="2025-10-08" version="1">MPKVLHQKRSSRTNCLAKPTAKRNGTKNHVTNGVKLKQQKQETHASPTSRQRPTFSELPLHPSHPKASAWGLYGTDDELGTLNLLTAEAVRAAAASEIRSGERLPLNLPLTTPVLPMNPRRKPCVHNIISKGYANDDELHLNTQASSHWDGLRHYPYQEAADGTHEGGPRYYNGVTQADISGLEKNERIGIQGIAERGVAGRGVLLDWRSWALEQGIAYSPFESHAIPLEQLKAVAVAQGIGAFREGDILLVRSGWIEEYRKLSPNEQVALAERPDRSFVGVEASRAMLEWHWDNGFAAVAGDTNAYEAWPPRRDWGVSCHEVFLSGWGMPIGELWDLDALAAHCKALGRWTFFLTSCPLNIPSGVASPPNALAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI80</accession>
    <name>A0ABR3YI80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="464" mass="50292" checksum="48365406A70835F9" modified="2025-10-08" version="1">MHYIRLLRPPNVVKASRPGQASALALVLTITTDLGESFLCPDAPISIAVEVVVDAVQDDKRDEDGEDDEAKDDGDDAEAEPPKTVVTHVFDLPVTAPVTAGKAKPGKPPKPTTGSGDGLSWKAGMRVLKLEAKLPKAAEACLWDTATVKRRIRIRPAGRTLSAVHARQLVGSRDGNGGLIMPLWVDVPDSASDGAFEHVALRRLAFDYNKDESTAAVEVEEEIGESIARHVWDAGLVAVAYLADMCLAHTPSRKRPREEEDEEAEVKPQSFHDVLRRTLLSRPKGLRVLELGSGVGILGIGLAAIVHEAEQASTSTEPSKNTFLLTDLPEAEERARANMARSAHLSLDYENLDWEDGREGRFGPAVTGAHGSNWDLVVLSDCTYNVDMLPALVETLSALADVPSSDLKKKPGVLLARKPRHASEEALFTLMKEHGWTVRASSTVPLPVLDNDAEIVELYLYEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIN9</accession>
    <name>A0ABR3YIN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000131">
        <property type="protein sequence ID" value="KAL1887284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF7">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="379" mass="41060" checksum="865F1B1BAFDB2E89" modified="2025-10-08" version="1">MGRSIEQDALTIDLRKLDSVRAASDRQTAVIGGGANNLQVARVLEQEGLATPLGLVATVGFVGWATLGGYGSFMNQWGLGVDNIVEAEVVTWEGKVITANEELLAGIRGAGGAFGIIVSLTVKVYALEKVLAGGILFAPQQFKPFLRMLESEASSFPPALQVGTAVFNFPGKVRVFRAELLWSSPDLDAGYTAIQRLKSLSPPSIGDDVSETALSTLIEKITAMIPPAYGGNETVSFATFDDESLDVLDQYVTAMPNDPATVIALHHLSPVSPSARPLQESMGSSWPLRCGHTMIEIIGSVRDKTKQFESRQWSVECRDALWRTTKSLEETYISMTYPGDRTLAQIYGSKWENLKSLSAKYDPHGIFELSVPRIRSGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY1</accession>
    <name>A0ABR3YIY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lysyl-tRNA synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">KRS1_1</name>
        <name evidence="8" type="ORF">Sste5346_010034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF9">
        <property type="entry name" value="LYSINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="277"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="464" mass="52751" checksum="D07D035A8D3693E7" modified="2025-10-08" version="1" fragment="single">MADSETPAQAPAAVPGAETPAAPAAEGADLHLDEVTGDRVSKTELKRRQKQRQRDEKKLQKAAEAAATAPKKTVGPVPVVEKDLDPREYYKIRCRQIEGLLKTNDPNPYPHKFLVDYDAHNFAKDYSHLKSGEVDKSREIRLAGRIFTTRRAGNKLIFYDIRTGADTKTVGTRIQVMCQAQYAKEDGVPFDKQHVNLARGDVIGIVGWPGRTSPKSRLDKGEEGELSVFASEVVLLSPSLHMLPTEYYGFKDYEQRFRSRYLDLLFNDSSRQILWTRSKMIKYIRDFFDSREFIEVETPTLASIAGGATALPFTTHHNSLNRELFMRVAPELYLKMLIVGGFNKVFELGKNFRNEGVDLTHNPEFTSIEFYAAYFDVYDVMAITEELVSGLVKHLTGSYITKFTTQHGEEYEVNWEAPWKRIDMIPELERITGKTFPPGDELHTDETNQFLKDLLKEKKLECAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJC9</accession>
    <name>A0ABR3YJC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF895 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010151</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF17">
        <property type="entry name" value="DUF895 DOMAIN MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="52516" checksum="2AE0CC20073FC435" modified="2025-10-08" version="1">MVSLAALQVAGVRYNSPWTQIILVGLVAFSSVGIFSAVGGLGAGGTQDVQLVDISSSVLYATFAITGFFAGSVNNILGPRLTMSIGTTGYAIYLGSLWSFQLHGTRWFVILAGAILGVCGALFWAAQGSIMMAYPLEKDKGRSFTVFWAIFQLGTLIGAAIALGIQFHSTLPGVSTGVYVTFLIIQLTAIGTSWLVLPPQAVVRKDGSLVELEPNVSPRAEFRAFLGMFKDWRLLVLFPMFFSSNYFYAYQGALTAFLFNGRTRALVSLLTGLGSMLGSVLIGFLLDNLPFARRKRALVTCSIVALLMVGIWAGGLAFQVKFKRGDTVVLGKPLPWDWTVGPAVGPILLLLAYYIIDAAFQGLAYYTMSSLTNDPFKLARMAGYYKGIQSAGSAVSFGIDAVRTPYLNEQLVSWLLTLVSLVLCAYVLYHTRDTNIDVEQTVFVEDLAPEKLEGIRVPDGHEAGAHTTTAEANVGVPVEVEGTTTKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJM9</accession>
    <name>A0ABR3YJM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC7</name>
        <name evidence="9" type="ORF">Sste5346_009581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="153"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="20"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="186"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="541"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="569" mass="65137" checksum="55847BC71223A5DF" modified="2025-10-08" version="1">MATGLRRKRFEEPFKIHEDMAFREDTPMINDVVAHLQSTLGEEEEEDDQQEQDEHDQDQDDQGYGGEDEDEGEAHPDDEEVILGEGVEDDDDEEAETAKSEAEEGPDDDNGEDDDEEEEEEAGDSSDDDAVDETVQYDMEKLQATFPSFRNQFRLIKRIGEGTFSTVYKAEDLQYERFDNSWDLDKDTEKWASPPLKRTRTASGTRSHSGQQHPDENDERHLVRDSDKPRRRAKYVAIKKIYVTSSPLRILNELELLHDLRSSPSVCPLITAFRSTDQVVAVLPYFRHQDFREYYRHMKISDMAIYLRSLFEALVAVHRANILHRDIKPTNFLYDPATGRGVLVDFGLAEREGSDTKPCLCHEVESVRKARIRAAYVPNAAHNGYPKSDTRPSRRANRAGTRGFRAPEVLFKCTEQTTKIDIWSVGVVLLTLLSRRFPFFNSADDVEAMIEIATIFGSKRMKIAGQLHGCMFETTIPTVGREGFSLERIILWSNCRIDNSKTLVPLSEDEKLAVKFLNRCLDLDPSSRISAEEALKHEFLSPKMTHRNNGHGRGQQYADEDDDEMDMIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJP5</accession>
    <name>A0ABR3YJP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046620881" evidence="2">
        <location>
            <begin position="21"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="184" mass="17662" checksum="8EE5FD460D264AD0" modified="2025-10-08" version="1">MKFFYAAILAVAALGQGILGAPVAQEEGVNAADRPPFGGPGGPGGPGGPGGPGGPGGPGGPGGPGFRGPGGPGFGGHGPHKREEEAGPGGRGGPGGHQGGPGGPGGPGPHNGPNPNPGHYNNGGNNGGNNNDHGDHRHHNDNNNNNNNNHGNNGNNGQYNPNPHNNGNGNNGNNGRHNGGPHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJV4</accession>
    <name>A0ABR3YJV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_009772</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="613"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1234"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1320"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1532"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="644"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1234"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1272"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1328"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1532"/>
            <end position="1548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1630" mass="178460" checksum="4CBCEA32844E6CF8" modified="2025-10-08" version="1">MSTYGFDGVDIDWEYPAADDRSGSPSDFANFPEFIKNLKLALDTSSGGRSGGRNGVTVTLPVSFWYLQHFDIVNLEPWVDWFNVMSYDLHGLWDKDNKWLGPFLNSHTNLTEITEYLDLLWRNSITPGKVNLGLAFYTRTAGTLSNAELTDMIRNAWATSTLDVDAAVKITAVGRNWITYDDAESWQLKVDFARSECLGGVLVWAISEDYADGTYSKQLQSVTNYRSPSVISVLSNGDGDGESTVDVPAAFVLRQQCMWANCGRSCPSGYTTVPRVDDSGSGIMNDGSRCRGGQLRTFCCPANEPIPNEDIIGDHSSEVGSTGIACNNGGFQVACCQTDSSIKSDLGYAACQWDGAPPDCNDNRNGVDPVSGICSLYDAPFTFPLFASPAGDGAVHCNDGFYKAVCPTGTVRLTMKDPTALSGCTGNQGGWAYCCTPRFLTDSENSQDDATAFAQALADVAQHGCGWTFPDDFLDDDDDGADDSTLARRLSIPSADNTTSLGKRVASDYNYKLVFADTFNMLGTAYKGQQELLEGGWNDGTQDAGLPNVPASRIESFPTGVQFSDMAGPTQSSYVHSVLEMLNDINFRPDAGTVLLLCPWWWDVDLSFNEDPDDGGVNDEQPYQRRKKRDTLSLAAEAVPASKQSSSGRQSGRTAANKTEAAAQYELARQNLLAFTRGSEDSLRQLYDVFSNSSDLGLEQLDFAEEDDVSPIHNSRRDGNDDTSISDVIGRGLEERVSTGSSRQYHVRSEHLSAALWPGAVINSSPYPNGDGGDNLIAATQDSSRYKVFSNGCCPQDYILNQFSAEASSSLWVSEHIIELQLIPRLLTALLDAELAPVPSIGMTAVPFRLVPPSIIEAFVITFPAWADLVEEDISPVEVALRHCGSSTDPFGIVVADGALNAIKGKLIGLVQPVADDAWAACCTSATTRATAQEAFSYIQNVMAVFDYFENTNVKDRHQNSYNVIKTTMQQFEDAYEQETGFLIPDIMQDAWRDFMIFMEQPGASGSGGADNEDANTTEYVRDDDGYLITVEELRERKEADAYLANSIREEIQVRERLRLESLRTRNPVAHSIPQEVYDRALNDPDSLTSSDCTMILARGDIYSRALIGAKHLLTQAQRYEIIGWPSPDVIEERIRAATKDMDVQMSTPAELVAKFERDSSDSLPPRAMQLLANNFHQAEPTAGYRAQRMAHADTMVVPGNSEAYKLALRAEGLSLQSLDAIIKHYVDSKMNGSGETMLQNPGQQFEPIPTVGPTVASSQPRESSHPGQPASIPPPPPPPPPPLPPPPPPPPPAQIPPVTLAPASLGGLSAFGGFGGLGGQGAAASSVNSSQNEPQHQQNADPPRRPLNFKPSGPVSYVPVYPRVQQFPVPGRSDPDGPLPIPGPNQVYRVIDEMADELLRIKGDNDWGEAYTNIVASMRGFALQFKSSPDLKLGPSEQHEESTRQRVRTYPPAPRLQLVPNPFGLRLSHGGGRLVGTPNNKSKLLNPAATQMPPWSNWSPIIPHQMAKPVYMQTIPHDQYVAAINEWTSKEEEARKQDLAEGREPPPFHKTPPAWPSGYSPKRDFNIFHESVQDLEEAQAWPKGDINYASEQWEAMSADEQAIYGKLCEERRRSAWLDSLNKRKRPRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJY9</accession>
    <name>A0ABR3YJY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="130" mass="14757" checksum="BBB72F3691AED89D" modified="2025-10-08" version="1">MEDRNEIVEKGIKAAYRDKIPGGIQHVFCVGNKQYWEFRDRPKAEFLPWLRLSGILRLRMHCLSKVADSQLVLATKHVQESIPALLNAVELWVASGAGGRDAEEKKAIRETLDRVENDLITVSIIHDPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK26</accession>
    <name>A0ABR3YK26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MPP10</name>
        <name evidence="8" type="ORF">Sste5346_009691</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MPP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000097">
        <property type="protein sequence ID" value="KAL1888217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="160"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="779"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="849"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="788"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="800"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="861"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="874" mass="95193" checksum="52E5F0F87317D572" modified="2025-10-08" version="1">MADSSTSSLTSTSHTLTIATANPYGIMMAPGSGSGGSMPTLGDIASALAFRDSTRQKPREAFLTPNAALSTASSEITQVALGTFAGQISDEQQERLRQMHAATAARKKRKRANKGAGAAAATEEDDDKFVRPIGPLLKIRRVHVNGFETPQIWQQSNRILATSTQQSQAILDQLEKEEEEEEGEEEDEEDGESEDDEETATNGVNVGSDDEDEEGLLEDDLAALEAEEDEDDDEDLSMGEDGEDDFGDEYDDEDEEDDEDDEEDEDDDDTGHGPAKELVEDGEDDFGDEYDDEDEEDDEDDEEDEDDDDTGHGPAKELVEDADGLNDGFFDINEFNKQSQWFEAQDARADPNTDAASEDDELDWHGDPFAAPMGKKGKADKKAKKGKKNGKKGRDADSEEEDAGADDDDEEDGPPIFGNMDLDAPSGESDIEDMDDTTNGGLASGNNFDDGMDLTANDIFYKDFFAPPAKKRDERARPGRKSAKTNGEEENKPFQPDDADVQRAIKDVRRDLFEQLSDASGDEDSDGIDALSDVSAGDVRSRRSAHERRQAKILAEIRRLEAEAVKGKNWTVSGEASASARPVNSLLEEDLDFEHIGKPVPVITQEITEDIEALVKRRILEQSFDEVRRHYGTGFGENEDGTRRGLIEIDDSQAKKGLAAVYEEEHQQAANPDTYVSQSDERVQAEEREVERMWLDVSAKLDALSNWHYKPRPSAPQMSVVADVATVTIEDAQPATAQGVSGGASMLAPQEVYKPGADKKDKDKGIVVVSRSGLPVARDEMTREEKLRRRRRNKERIRKSGSGLAANGNGTAATGVSAAAGNNGGSSTNASQADTIATLKRAGVKVIGRKGELQDVEGNKPQVSRALSSGNFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL71</accession>
    <name>A0ABR3YL71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tubulin-specific chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009339</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058033">
        <property type="entry name" value="ARM_TBCD_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033162">
        <property type="entry name" value="TBCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022577">
        <property type="entry name" value="TBCD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658">
        <property type="entry name" value="BETA-TUBULIN COFACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23579">
        <property type="entry name" value="ARM_TBCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25767">
        <property type="entry name" value="ARM_TBCD_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12612">
        <property type="entry name" value="TFCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin-folding cofactor D ARM repeats" evidence="4">
        <location>
            <begin position="448"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin-folding cofactor D C-terminal" evidence="3">
        <location>
            <begin position="1131"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1409"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1409"/>
            <end position="1424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1467" mass="155315" checksum="5F7108E2B4DCBB33" modified="2025-10-08" version="1">MDANDEEADVRLQRIASDLLGDFDSSLEPFLFKPSTTGANGAKKGARRARPRVRSRETYRIAHLLEPFQEFPQLLDVYLARWLPMLADAFLQSVERNSQRSNKANATAEAVNAAALAEAATTTATASSGAAAASSASSASSLVMPLQAAVARIMYTVCKVRGEKVVIGFLPNDTKYLEPLLGALEAQAGDMSSLNTGTSDDDSNNHGSWAWEERYLVLLWLSQLLLAPFDLSTISTGRRGRVDDEEDEEEDGEAKSKLPVIDGFTWPGVESTAIPSITLRILPLAVRYLAVPGKERDAARALLVRIAMRRDMQELGIRQSLVQWALGSLDGREAKTTAEVSSSTTSTSAPAIRQPYYYIGTLSFLAGILSAAAGASDMDDALAPIFAAVNAVAEEEELEANTAHQTAVFAAIRSSALARKMMIKATRAVAVRYIQLLDQLGETGPDDNSELVEAADIAIETTIGYLLGRLADNDTPVRFAASKALSIITLRLRPDMAAQVSDAVLEALEKNVLAQNGKLDFTAVDPLEWHGLMLTLAHLLYRRSPPLEALPAIVRALQRGLAFERRSVSGSATGTNVRDAACFGIWALARRYTTAELLPLNVLQMLATDLVVAGSLDPAGNIRRGSSAALQELIGRHPDTICEGIPLVQAVDYHAVALRSRAVTDVAQRATALARNIYGVALREALLGWRGFADAGDAGARRTAAQSFGQVTYLMATAAEGREPGKTPLEYFATTVSTLVARIKTLQARQVEERHGFLLALAAVLDIFPSLAESAAFSQDETSKMTELCLSVLDQLHQVLEKCKALSAARRPELLAEAASRLIVSSFPIVQAAVLLGADIDKEQGLVLISGPALVAEASLLPAPLFQKTVLALDTAFALSAGSDTVAPTRTAIKTYTTLAAACLSGPNVWLSRQEADVIAAASDAALVLLITLGPSAPFTSTTVPSVSPVPPTRDSLIAFWSGVVCKPKAAAAVSFKARASGSGTTGTGYVFALTKAYPLHEITSQNVEPTVASDDDPISRAILGRWAADRSIDTRMALLQALAQCPAVLMQRAAVSTSSSSSVTPPAPGSRFRSMLAAGLDDYTTDARGDVGSHVRMHALRATQVLWTQEAALGSGATPKPAGASILFFRVLRLATEKLDRVRVAAQATLAQAVGGDRAAYLQSLPFSSQAYFRCLLGLWEDITEVNDTNQSSIAAAAAKSGDISSSSSSAATKWMAALMRGYVTSADTGNEELVVASRAAMVEHVVNAGEGDQEKRQARQQCLWQALLRNLPGTSAAATTAAGKVITPPDRIVVPTLEIIAFLFNAGVFLPPTSADSTTTPTHADLLDLCRQVNEAVEKAGSVRKVEACVKVYGAVAASDRAATSEEGGGRVARAKLAELLQHPWPRVRNAVVDELWGLGLDQGLDQADAGTDADPAAGPTTLSSDREPASPSISASFDVLKGVDWVAADAAALQALAGKLGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE4</accession>
    <name>A0ABR3YLE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011666">
        <property type="entry name" value="DUF1604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07713">
        <property type="entry name" value="DUF1604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26093">
        <property type="entry name" value="HTH_TGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="156"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="690"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="744" mass="78901" checksum="0271A300415B6296" modified="2025-10-08" version="1">MSKRSRAAYEADLQAQQSPYVAFGSPLPPVDPNVRDDGSYVPVWKQEVRDAQGRRRLHGAFTGGWSAGYYNTVGSKEGWTPSTFVSSRTNRHKDKADATQGFKPEDYMDEEDLADAEEARKIHMSDAFAGLGTTADDSSRPMAGGDLLAGLFSATGETMGTKLLKKMGWKEGQGIGPKVRRTARLDVGGAQPEGKKTRTTYLFAPENVVVMRLVKKTDRKGLGFQGEGRLGSTASQANKGSDDDSNSDDNADGDNNGITRGLFSKSKFLGGKAKGKPARSVGIGLGVLNDTGSDDEDPYDMGPRISFNRVIGGDKKKKKAKQASALRDDGNGDRAVKPKLVFARGGVLGKGSSQVCHDGRPPLQGFILGKKADALTSDVNANNKFPPPAIPPGWKSSKQPQDKGSSLTAGVQADGAYLSTADVAKASTLNPKSRAAVLGESQLPGKSVFDFLSPEARDRIAAATGRQDLPEARSEVPAEYALSEQEKKDQLLQVVPSLDKATAVAAITRGARGGGPYQDNEAKRSRYRAYLEFQAGITPNLPPKPTSMKDDDWLREAHEFFNCARIFKPMSGLMASRFTTSTSSNSMSTASDGDKSANLVTRPAPKAQDPAEEAAKMGMYGPMTRTVSEFFPSRLLCKRMGVKQPDIVPPDGDVDMGQSYGTSSSSSLNKPPYGSGGNYGATAPPPAPASAPSSGPATQNPTPAAEAAAAAPIQPGHNEALEGKRAGEDVFRAVFGDSDDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM95</accession>
    <name>A0ABR3YM95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase F0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013920">
        <property type="entry name" value="DUF1774_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992:SF1">
        <property type="entry name" value="DUF1774-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08611">
        <property type="entry name" value="DUF1774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32384" checksum="B9807E214C9A991E" modified="2025-10-08" version="1">MDRYNPFSRRESRTRSELATYRVLTLASWALVVAVSIYYSVKSPHGWGHNAHRIAVQNRLHPTAFSLNMIIVYIYFISLYLSQAGYLGHLFASAHQSERVVAAVAVGSHFIVNNIFHTLFVLLFVSGHFFWAEVMLLLNFVNLTSLYFRHPSASHPRGLVHTPTVAGPLAWTFVAIYWNGAIMVPHAQSLAMRILANVFVWAILAYGLFYVMIYADYSMGFALSILAAALGTGQFLRQIVALQWIFAFAVMSILFLATVAVAVPAWTGREPSVLVISRDSERAPLLDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMR0</accession>
    <name>A0ABR3YMR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF27">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="22"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="524" mass="58610" checksum="FCC07BDCA297F30D" modified="2025-10-08" version="1">MASLLTAVRDRTQYFNRRLFLSVSLIALSSLNYGFDNQAFSTTESMMPFQKTFGVFNEKTQTYSLPSVWLSLFNSLNYITFGIGVLFGSFISSRFGRRWCMFGMSCYALVSATACVTSQNKSQIMAARILNYFYIGMELSVVPMFQSEIVPAPVRGLAVATYQLSIALGGLVINGTCFATNNHYKDNRAWRIPLGLFYIIPTIIISGIWFVPESPRWLLQQNRVDEARHNLDLLRQGSARYDSEEVIDQEFVELQKQLERESEKGSFKEIFRGRTNLMRTFIAVVINFFQQASGQGFISQYGAVYVKSLNTFNPTLFSLLNSGISVIVTITVLVTSDKIGRRTSLFVSSIVMIAALFTMGGIGTQPTPLSTASKRGIMSMITIFGVGFSIGWAPLTYVVATELPALRLREHTLRLGFLINVIFNFAVNFSIPYLINADYANLGSKVGFIFGSIMVLSMFFVYFFVPECKDKSLEQIDFLFNCGTRLRDFGKVPAASVAQDAVFEKHVRGQDVEEAAVTVESKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMY2</accession>
    <name>A0ABR3YMY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009011</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="123"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="255" mass="28680" checksum="08FB5B103FAA439C" modified="2025-10-08" version="1">MDSFASFWANTLATYGPRKTEFFGFLIVQFLSFWVPSALYIALDSIAPQFSERHKYQPAPKQPTAADIRHCAAVVLRNNALSTALSVSLALLSGDPADHANKLLGLRIDSKLPSLGEFVRDIVLSCAMREVLFYYSHRLLHQPRFYRTIHKTHHKFIAPVALAAQYAHPIEHIVANVLPVGLPPLILHSHVLTYWAFVAFMLVETATVHSGYDFFDGAAKMHDAHHEKFNLNYGVFGIMDWIHGTDGLKKAKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNS4</accession>
    <name>A0ABR3YNS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06185">
        <property type="entry name" value="PDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46696">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46696:SF6">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="488"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="724"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="812" mass="88790" checksum="DBBD1D025FB8D69B" modified="2025-10-08" version="1">MAAAATAPATCPVPHMAGAVPPPSHPPVPASDSNLSDLFTQPGRLFDDLAAARDKTDGLLWSDRLGAYVVARYDDVVCVLDDADTFSSRPTVPDMPPPVVAAMAGRCPMRGTLLGLDNPDHDRLRKAVASFFVPRRLERFAGMMEARAHALLDKMVSRASRAADFGERGVNIREKFNHALPLQIITAVAGLDVDRWEWVGQALELTTVVAKRPEDDDEGDGKQKEPESDYVKLGRYIELHEYIADLIQQRKTDRRDDLISHIWGERDSGRVTMTDFEHLSLIPGLLLAGHETTTSVMTMGMAHLLHLNLWETATRDEPSRMATIEELVRYESAITGMKREVLKPVTIGGTDLKVGDIVFGAYQSASRDPTKFDKSDVLRIGVQSQLSLSTSGKGQQQHLGFGRGIHACLGAPLARLLLRIEMRVLPERLPSLKLVTKYEAREYTAVQEGRDLLKLMVSWDVEAAAAVAEKRAASTTSQSTAMPRNTAAVETSVVIQSINRLNETVVEIELAAPDGGPLPSWTAGAHIDIPVGGDLGFRQYSLCSNPSDSDVWKIAVLREPEGRGGSLHIHSKLHVGQQLNIQGPRNHFEWKGADSPKHTSLLIAGGIGITPLRAMISAAETAGTDYRLVYLGSSRDRMAYADEMAANPKSTVWAKDEMDSFDLQSLVVDHKAEIDSESLAVYCCGPQRLLRDVEDMFQPHLPARHIHVERFTPLEVDKSTNTAFDVMLARSGRRVHVPVDKSILEAVREAGATPAVLSTCTKGTCGTCEVKLVDGAAEHRDTVLTADEKAAQTSVMVCVSRCRGKELALDLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP55</accession>
    <name>A0ABR3YP55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="14">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MUS81</name>
        <name evidence="16" type="ORF">Sste5346_008431</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21036">
        <property type="entry name" value="WH_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047417">
        <property type="entry name" value="WHD_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21136">
        <property type="entry name" value="WHD_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 14 16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="15">
        <location>
            <begin position="285"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1890138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="597" mass="66118" checksum="4D2AD0C098D059B2" modified="2025-10-08" version="1">MSEECPNPLFLGWVKEWWDQAKERNTKGVLAYRNAHESLRACPIRFEHPDQLLALKGFGAKMCSRLLEQLKQHCAANGLPVPPKRRQAPATISRIAATAPGPSSLTRANNHSINEGVVAGQRPRKRRAYVPQLRQGGYAILMALSSPEAEGRDWLVKPEVIELAQPHCDASFTIAPPGKFYTAWKSIDTLLNNDLVAERGRPSKRYALTEEGWEVANKLRDAVLGGAGGVEAAAQVAQPLQIPDGQAGLSTAVLDLVPDGPAVTSDDVLPSVEPIELPAGSFSVRLVLDMRERVTGQRTYMEDELAKRDAKPLVRALSLGDALWVAKIHDPNLLSILGSEGDELVLDWIVERKRQDDLVSSIKDGRFREQKFRLRKCGAPHVVYVIEESGMDPDMLHKYEEAMQSAIASTQVVNGYFVKKTRTVDDTIAYLAKMTKRLEAQYANKPLRVLPTASLTTQNHMPWLQKLRAKHTGGSMASATPSYCVSYAAFASLTSKSETLTLRDVFLKMLMCTRGVTGERALEIQKVWNTPAAFAQAFEQLESKIKVAYDDFDVEADAIRKRKREMVFDKLGKLPGTKRRVTKPISEKLGEAWGGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP68</accession>
    <name>A0ABR3YP68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="313" mass="33901" checksum="9E8C3C95D869632B" modified="2025-10-08" version="1">MVRLPPAEKLPLALRKNIRDSWENKKSESEQKISEILGTAWTIDINPNAIYPYGDSDYAKDSLGDLIHGYVSGAAYQLSDFARSFGADGINDLNAAASAHVLTMDVDDSTSPVSYCGAAIKDGKLVIIFNPKSLGTNDSDALQSSNITKALNEAPAAAEGGASGLSFSAKDGIRKGYDAKVGAVQGSIAEQLGKSKDDVKLVPNFENLYTTLQANSSKLSSNWEEQLGPFVLQYFEGVQSNLAYNKCKEDEMIQEGVNEAVDKSTFEMRIVDKLKYASYCEVVVEDGKLFVQTTVDRWGVNIGDAANKIIDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPK4</accession>
    <name>A0ABR3YPK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP16</name>
        <name evidence="16" type="ORF">Sste5346_008669</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048938">
        <property type="entry name" value="ATPD_C_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21334">
        <property type="entry name" value="ATPD_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="33"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="F1F0-ATP synthase subunit delta C-terminal" evidence="15">
        <location>
            <begin position="119"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="162" mass="17438" checksum="08A4642D99C72C8E" modified="2025-10-08" version="1">MNSMRIARAALRARPTMASRVAFQRRTYADAIKLSLSLPHQTIYKSQDVVQVNIPAESGEMGVLANHVPSIEQLKPGLIEVIEESGGTKQFFLSGGFAIVQPNSVLSINAVEGYPVEDFSAEAVKTQLAEAQKIANGAGSEQDIAEAKIEIEVLESIQASLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ3</accession>
    <name>A0ABR3YPQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008548</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342755" description="SET domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="152"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="449" mass="49790" checksum="37AC95C9D0CA01FC" modified="2025-10-08" version="1">MTTITSRLAILPFLALVGATTVPVNDIDIRTCAPRIPAPLQRHSRFTCPLTLDDVSAQARGPSSWSPWTHLPVCTEAKEPGFEKIEVKDHGENDDGEDDDDEEEEQDEDEDTPQTRFCVYTNNRHGIGGLSIVTTPETASASMGIWDESLPQPLEMAANTSLAYEIIDIPGRGKGVVAARKIKQYEAFMVDYAALVVDLRVAGGSVERNEGYRLLQAAADQVSDPQRVLGLAQTSTAARHPVENVLRSNAFHTALGAEGDEHMALFPDLARINHDCRPNAFPRFLPHSLAVNVAAARDIVPGEEITISYIPLGQTRIARQKALLRWEFVCKCPLCAASEADIEASDARLTRIDELREKVAEAVDHRYSSTRAEKKAALETIRDLFPRLYEEDLFTAYSEQYASIARLYWALGDHGQAQFYAQRSLDVLADQGFIAEADRDKVHLLMRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQZ9</accession>
    <name>A0ABR3YQZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="22"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="275" mass="29835" checksum="A437D2A3D21422F3" modified="2025-10-08" version="1">MVRAPVIALSHGGGPMPVLGDPSHSDLVESMRTKVPAILGLNDTERRPKAIILVTAHWSENVPSISSGAKPKLLYDYGGFPPEAYRLKYDAPGSPEIAQRVSELLSAKGFKPDLDDERGWDHGVFVPMLLVHPAADIPVIQVSVLASEDPAAHFKMGQALAPLRDENIAIIGSGFASFHNLRLMFAGITRDPAAAAQLKEWNAAVTAAATEADEKSRLTAFEQWRNFPAAYITHPRGGAEHFLPLIVCAGAVGNEKGKTFTDRFQGLDILSYYWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR81</accession>
    <name>A0ABR3YR81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008603</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="57"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="174"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="284"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48550" checksum="5DDEA52062115391" modified="2025-10-08" version="1">MRGRLLSTTSSLTSSLRRPARPLLSFTSRHATPLAFSSRLIHSRATDFLPANLPEWSDAQRSVREAIAKIVTKYPDEYWMDHDTEHKFPWELYKDLADNGWLGICLPEEYGGSSLGIAEAAVMLQTIAESGACMNGASSVHMNIFGLEPVAKFGTTEQKKRWLPPLIAGKERACFGVTEPNTGLDTLKLQSTARREGDHYIAKGSKIFISTAQVSEKILLLARTTPLDKVDKPSRGLSLFYTDLNRDAVKITEIPKMGRSAVDTNVLFFEDWKIPAEDLVGNEGDGFKIILHGMNAERVLVAAEALGIGFAALRRASQYASERVVFGKPIGSYQGIQHPLAECWMNLESARLMVYLAARQYDQGYTGGEYANAGKFLASEAAFKAAERAVLTHGGMGYAKEYHVERYLREATLSRIAPVSGEMIKNYIGQQVLTLPKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS90</accession>
    <name>A0ABR3YS90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008053</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045516833" description="Cytochrome P450" evidence="7">
        <location>
            <begin position="21"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61504" checksum="01E76C14931931ED" modified="2025-10-08" version="1">MTPLVKTSILLLVVAAVVRLLMVGRRPKNYPPGPPTIPILGNIHLMPKRDLHIQLRKWADQYGPVFSLILGTQTLIILSSDQAVKDLLDKKSNIYSDRPELYVGQKLASGNLRLLMMGYGQTWRGFRKLFHSLLNVTASKTYLTYQVLENKQMLYELITQPEDFLYHIRRYSNALTTTMVFGWRTPTYQDDKLMQLFDGFSEFADLNQTGAAALLDAFPLLRNIPESLNPTRRLAKTLHAKEKALYLSHWLKAKDEISKGTIAPCFCVGLAEAQKKEGFSDDQACYISGTLLEAGSDTTSNTIYAFVQAMLLYPEVQRKAQKTVDDVIGEDRLPTMDDDASLQYVRAIMKETIRWMPTTILGAVPHAVTEDDYYNGYLIPKGAGVMNNVWGIHMDEKRHVEPRRFDPDRYLDDRQSLGEASANPDPAKRDQFTFGAGRRICPGIHVAERSLFLAISRILWGFDITPALDAQGKPILPDPEKLTQGFVCMPEEFKATIRPRSEVRKQKMLAEWEAAQKENLDPVTKQWRNTAMDKDMWKVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSF8</accession>
    <name>A0ABR3YSF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046894715" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="58949" checksum="5A52A6D6537844E9" modified="2025-10-08" version="1">MRLHLLLASAATVTEAVFLVATDQLQDAAGFSIQLPGHALASAAQIHKDTAAAVSPILGCTTSSFSIPSWFVYNLTYYRDDDTATFSIVNRATNYTADIGCNNATADESKPNLYSHCQILTDPATNDDALLALVRVTQKGTAANVLLRQTWTCNDRNTTAQPIKFSAAGNSSVPLKCGNGINCPAVDSTLLVRGNLAAPVAIHPAPAEGPIGHSKAGCSAATTKPPSWSLQSVYYLNQTGDNGATALSSQTLMLQVINHAIGYQAGCTGFLSDDLSTKPVSFTCTGQGYDFIGKDRYRISTQALFEPATFNFTVNQTWYCDDVDAGKPVSITASGSTVLPLNCTSVAVGSGATSGNKTTCLSTSDILVQAQKPGTATPLPPYSITDPLPTPDGCTVSSIVGPAWTMSSFEIDSDAKSNNTLAGTNITDVGFNLQFSTGTNEFTYPVSVYQGKPVDGKPQWFHCTFGADQIPLAPYNCTFTYDDAKKQLMLAADWICSDLDKANPILFSGTTTTAVTKPFSCSTDGGQTQCLTDETATWNAPIVNVTWRPADKNVLAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSH0</accession>
    <name>A0ABR3YSH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007942</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="204"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="422" mass="45381" checksum="CB5C8EB525408FD9" modified="2025-10-08" version="1">MDDFVPPPPRPPPFLPPESLHHLCTHGYLGLELPRHLAIKYDHLLATSDAFFAQPVDAKLPYRPATDRAPGHLGPPSNPNNTERGYTHLDGEKEYLTLRKSMTHLPLGIYDAAAPVWHDTAHLLHRILGDIGVYLGLGPTAWDSVVADSLEPGDGVYYSDAVISGAEGDQDKGKGKGKGKAEGKDGDTPAVDKPPKRHHPRDDPPTLLRLFRYEPGGGGAEQHRDLGLLTLCVCWGKGLQVRPQPPRPLPQPTVDADGNSVDPSLAPPVPPPAAPEWVDAPRVTVMTGDTLHVLSTNRVPSALHRVVVDPKEKAEADSAAVTGDSPPYKSRRSIVFALRATTAGDIALSGFGGFGSVGARELYDSIRKSRVNINADKERRAVMRAEYEKAKALDKPVEEPPANKCDAMDGDTAIEGEITGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTP9</accession>
    <name>A0ABR3YTP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">wis1</name>
        <name evidence="9" type="ORF">Sste5346_007479</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="305"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="336"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="687"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="54"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="711" mass="73819" checksum="DB4F99847D364322" modified="2025-10-08" version="1">MSHPDVSAASTPDEFPDSGPVSPGSVDESSGNTTPGDHTSLFGENPLFPTTANRSPSSSQPPRRVPSVRATSDPSNASSTSATANINMSPSSTVTGTLNNARRPPPSASNLPLDLMAKARALQQQRMAMSGPGGANGPIGDGARSASPGTMGGGMAGGMAGGVPGNLRMHPHMNRGMNLGGMARPTAPGFQSAPAVPNLSGRPGGPSLSERRAMKLGPLPGNAGAASPRSGPPKLSDMGGGAGPGAGGPGRPPLKDGRHDSKMNDFKHYIDAEKGWITFEGAATITRTGVNFAGGHTFKISLDEIQVLDELGKGNYGTVFKVRHAKPAVPRFGPGLSSFKSNHAKQQQQLAAAQSSQSTQSDGTAGSCDKSGSNGTVSTATTGKVMAMKEIRLELDEAKFSTILKELVILHECVSPYIIDFYGAFFQEGAVYMCIEFMDGGSIDKLYAGGIPENVLRKITYSTVMGLKTLKDDHNIIHRDVKPTNILANSDGQVKICDFGVSGNLVASIAKTNIGCQSYMAPERISGGGMSAGGANAEGTYSVQSDIWSLGLTIIECAMGRYPYPPEVSSTIFSQLSAIVNGDPPDMPEGYSPTACDFVRSCLNKNPMKRYTYSMLLNHPWLKPLTQAATVIEEEDESDSDSDLDSDDGDKDGDGTASAVNKLSLNDSGVAGDAEVAAWVTGVLERKKSESNEAANAASAKPALHAAPLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU7</accession>
    <name>A0ABR3YTU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Plasma membrane channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="8">
        <location>
            <begin position="23"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="7">
        <location>
            <begin position="212"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="769"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="779"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="800" mass="89591" checksum="92938B711400EBF9" modified="2025-10-08" version="1">MASISDIYGHGAADKPELNNNFHVDYVIHFLIPPKEREEAEAAFIQVIQALANAGFATEVRPGGDRASLLIFCKIASEKLLRAQIYRSRLQDYLYGIRTTAPPSRKNQGGVDVDFDSYFADEPVSEAERLRLAYLLITKPRAEGGAGITPKGTLGESSSPAKGGPGARQTNVGTQNKFVASIFPLHDHAFNRAWLRKWSTKYMLDAADLDAIRDKFGERVAFYFAFMQSYFSFLLFPATFGFFAWLTIGQFSWIYATVNCLWSIVFFEYWKKREVDLAVQWGVHGVSKIQLARPQFRYEREAKDPVTGETVKIYSPFRRLSYQLLQVPFALACVAVLGGLIILCFSIEIFMTEIYGGPFKQYLTFLPTILLTVFLPLLTGVLTNFAEQLTNLENYETQDDHQAAFVQKIFVINFITSYLPVFLTAFVYVPFGKVLVPYLDIFQITTQRLTGDDKTDHAAHKAAFQVNPHRLTQQVIYLTVTAQVVNFLTEAVVPYVKRKVFKAVKDVSEEIAHRGQADHLTKDVPEEAAFLERVRNEATLDVYDVTIDYREMVVQFGYLSLFSVVWPLTACSFLVNNWVEARSDAMKIAISSQRPIPWRGDSIGPWLTSLGFLSWLGSITSAAIVFLFRSNTFGPDHSPWDIKAWALLLSIIFSEQVYHTLRGVVHYVVDKLDSPGLQKERAERFALRKLVLAESLGEAEAEKAMGGAGVAGPGVMDGEKITREAVEAEARELSAKGQDTPEEVFWLRQRGPSESVEVGRTLIAEFTVANGNGNGNNGNNGHNNNTNNKSTTVPTPVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUM4</accession>
    <name>A0ABR3YUM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF11</name>
        <name evidence="5" type="ORF">Sste5346_007243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="22"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="157" mass="17516" checksum="2DA638950BAD4148" modified="2025-10-08" version="1">MPKNKGKGGKNRRRGKNESDKDKRELIFKEEGQEYAQVIKMLGNGRLEARAFDDSGTMRLASIRGKLRKKVWINTGDVILLSLREFQDGKGDVILKYSSEEARNLKAYGELPEHAKINETDTYGDGGEGDVGFEFDEERDESSDEGGNAGDIAIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUV5</accession>
    <name>A0ABR3YUV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">TFIIH complex serine/threonine-protein kinase subunit kin28</fullName>
            <ecNumber evidence="14">2.7.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">KIN28</name>
        <name evidence="14" type="ORF">Sste5346_007266</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.2" evidence="14"/>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07841">
        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037770">
        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="82"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="15"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="373"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="427"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="443" mass="48860" checksum="BFAA64A83F419D61" modified="2025-10-08" version="1">MSASPLLAVPTDVLTASSAASSRPGSALPSRPPTHSNGSTPHGGAAAAAGTGTKSQTQPPQHRHPITMDVAERLNEEEKNKYIRGKELGEGTYAVVYEGRVRDKWNQLVAIKKIKVQKEYSDGIAPDAVREIKFLQELHHPNIIRMHSVYSTRDQNLCLVLEHLPRGDLEMLIRDTAAVRYGAADIKAWMGMLCRAVAFCHDRAVLHRDIKPNNLLVAADGALKLADFGLARSCADPYRVMTANVITRWYRPPELLFGARHYTGTVDVWSVGLVFAELVIRNPYLPGNTEVEQIGLICRALGTPNEDNWPGVTRLDSYTVPTDRVYPVATRDTFLGPFGTVGSEGVDLLMKTLVLDPRRRITARAMLDHPWWHAEPRPTPVQDLPRRNVAAAEKEKEREREAARMAADLKRRPGAVGGGSGANTGDEQDRGAKVARRLDFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW37</accession>
    <name>A0ABR3YW37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein JIP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">WD repeat-containing protein jip5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">JIP5</name>
        <name evidence="7" type="ORF">Sste5346_006983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="339"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="429" mass="46096" checksum="E6AD4817AE90126D" modified="2025-10-08" version="1">MLENLCKLPLSADVFAQVLHPTEPLLTVGLSNGRVECYRLPESGAGNDGKKAGVIKPLWTTKRHKGSCRNLAYSIDGKWVYSAGADAIVKHFDPHTGKVVSKFAIPPRRDGALDPPAILHILSPQTMLLGTDDGFLYIYDLKEDGSVAAKPSRTHKPHDDYVTSITPLPPSAESTSGYPKQWVSTGAGTLAVTDLRAGIIARSEDQDTELLCSTIIPRGLGPKNLRGNPVVAVGTGNGVLTLWDKGAWDDQQERFYVAGGRNQKDGESLDAVVRVPDSVRWSNGQTVVVGAGDGTVSIVDLRGREVRQVLMHDEVEGVTAVGFDSLGRLVTSGGHTVGIWQENKDANGGGVGGSDDEDYEDKDSDDDSDDSDAPPKKTASKKRAADSDDSDDSDSDDSEREQTKRRKKKNKKGRKGKPQAKRASFPGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWH1</accession>
    <name>A0ABR3YWH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052772">
        <property type="entry name" value="Endo/PolyKinase_Domain-Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535:SF1">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="169"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="415" mass="45267" checksum="66E665D4FDEC1169" modified="2025-10-08" version="1">MARRKKSPKAPQTPQSPQAVQSPQTPQTPQTPSPQPKAVEKSPEDQLAELVEKYGQFLEESIIILTFQDHGFEVANEFLASLAENVFSEEASGFDPSGLQGTATDGANDASEGSSYHTPVEGPSQVASISGHGSGSTSGSQYTPLSAGGGSRSSAVDDWSAVTNDLPSDGSSTLAILRDAFPTVKDSDIKRALKESDDDVDRASDVLLNLEHLIETGQRPKGIDGFAVDDDDAYEWGSRKKKNNSHNNKATWSKNHREKRLALDYKLAPLGLDGSYEIDDGSKPAPKRGSSQPFRDTTARERRQGNAQLSLYDAIVDKQSKDALTVDLHNVPVKDGIRIAMERTRYWWAHLGEDRVRKARENPLRVVTGVGLHSPEGYSRLNTGVEAALKREGWKFHDGFGYYDVTGKTIAERTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWH8</accession>
    <name>A0ABR3YWH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006816</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the velvet family. VelB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="8">
        <location>
            <begin position="147"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="475" mass="51852" checksum="A3EA0424149AD98A" modified="2025-10-08" version="1">MQHDMHNQLPALGHQSYQQPHQSTHLPTMSLPPPHGYADQYQHPPPPHSQHSQHSQHPQHPQHPQHSQHPSHSQHPPHPQHPQHASQHSQHSQHSQHGQHAQHAPPPPSLSPVDPTRSPPTPALEAPKPTPEQEAATRKALEPTVGSEGTRSYRLDVVQQPKRARMCGFGDKDRRPITPPPCVRIVVTDLATGKEVDCNEIEHTMFVLNVDLWSEDALKEVNLVRHTTTTPSISSTTPASYEQVENAPTYSSLIQSDSRGPGYGSSMYGHSGMTPYGQSAYSQVPPSYMHQSNGYGQSSQYGGYHGGDYGMQLSSQAPGYGPPRVFGGPGDMMTQRLIQGNQPQGMFTRNLIGSLAASAFRLQDPADKIGIWFVLQDLSVRTEGNFRLRFSFVNVGPPSASPSGAPGSQIVNTGKAPVLASCFSDVFTVYSAKKFPGVCESTVLSKTFATQGIKIPIRKEGIGKNGRGDDDDDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWT9</accession>
    <name>A0ABR3YWT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="723"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="783"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="847"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="868" mass="95885" checksum="871EC91199E793EE" modified="2025-10-08" version="1">MPPPGGNLTGNTLSPLNSNQPNTSDRPASLLSPVEYDADAVSIRSDQDSDSDDDQLQQRARNSRELRAHDRMVFLEEDETDQLVLNARREQDRGRRRGSNLAIANPLKFLGIRRYSDGSRSRSPDPNGEGRGGTTPRSTVTNATTLRASTSTDNFHDEKTGSSKTEKRRQRRQRRKDKKKRLLSQARDGEDAELMFEMEEGGMKEGSSTGESSERDDSDEIDRRGLAGLTDLKGRRKRRSWGRWLLLHALIAVAFALLVLGAWKMTLVKKAEHQQQQDTLKGDKPAKARTLVSNGTCLFAPTTLIISLDGFRADFLNRGLTPRLNAFVREGVSPLYMLPSFPSVTFPNHYTIATGLYPESHGVVGNTFWDPEFKADFHYTDPDRSLDPKWWGGEPFWVTAERQRARTAVHMWPGSEAHILGLEPSYVDKYNGNEKLSKKVKRILEFLDKPGLETAAADDVDGMNVPNLRPQLIAAYVPNVDSDGHRYGPNSTEIRGTIAAVDSMLNDIFAGLEARNLTNIVNVIVVSDHGMATTDVSRLMQLEDLVDMDRIQHVDGWPLVGLRPKGDAPEDLEALYQSVLNRTSDNPNLEVYLRDVNMPERYHFSNNPRIAPLWLVPKAGWNIVQRAEFNVAEGLANDLVYHPRGLHGYDHEHPLMRAIFVARGPAFPHAPNSKLTTFQNIEVYNMLCDSIGIEPRPNNGTLHLPLKPVGLHDAPPVEPEDPVPAYTKESSTVQTKSKTTSTTATTKTTPQPIPTQPTKAATTQTTQTTATTSATVGVDPVKPTTKTSVSSSSSSSSTSPSQPSASGSPGDSKNDKNPLNKVADAAGHLWDWLTDKVGEVWGKIKGHGGDADDKKEETNEAAARSRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX04</accession>
    <name>A0ABR3YX04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14364">
        <property type="entry name" value="CUE_ASCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052586">
        <property type="entry name" value="ASCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041800">
        <property type="entry name" value="ASCC2_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494:SF0">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="370"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="707" mass="75235" checksum="30C71E4AAF207491" modified="2025-10-08" version="1">MTALPPFALFPDSAAWRQQIGPTDWALYLSSWRALAAAYLALPDAAFAAALANDEQTGVSSFLVSLARALVEAGPAALAPYFSTNSGSEGDAAAALKKSAFLLTARALRLPKPPPPALLSWEHLSDVSRVYGRRRTGHVLAKLPPASVGVAEASLSALKKYLIKNMEEGSAGKGDVRAVESRLLRVNYLISAWPAAGALLLTGSDYLDGLAACFVIMNPPLRRAIVTNLYVSLIGLTEPPTPRYSLLSDLLYALRAAAEEHKKGPLRPSDSLVAELVSVTPLLQQIQQRAEAPSSSGSTGAGTSTNRILPILKDLAKFKKPGSGLHLPPGRLKRKLDKGKAAAPAPAPVAVPSSSAAGAASSTPPTLHPHKLSQIAVVQDLFPDLGSAFVAKLLDEYNDDTEQVVACLLEDNLPPHLVGLDRTENLGHVALSDAPPPDNQHTSMAPHATPPLPPSQRNIFDNDELDSLSLETSKLHFGKSKAKTTADDLLADRSSSKAPNKAAIWSALAAFDSDDDERDDTYDAVDVGGTVDNSVPAGSGAAEDLHAANEQTLYAAYMATPDASVFQRDAFTRRSQERAKLREETGMTDEALEGWAMMLARNPQQRRRLELQSSAFGGEQTQLERTSWRAGEDDEEDGAPSRGGFRGRGRGGPPRGGGRGRGNVAGPTGDKDTQQARNRKEANKGSRANHNRRDQRAKKMARGGFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY31</accession>
    <name>A0ABR3YY31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="727" mass="82112" checksum="B930043BA6677C92" modified="2025-10-08" version="1">MFARRENEKPLHLGLTAHCGLCGTAMKVGDACTALLGVDRATVYQRRTPPFSYPKYAFFHGEESAGKDPDHKPKEGEDEDDSIPMMCRNPECTKGTATLEACTVHVNCHAMFRKHCVGVRGNAGSKESLDRLWIAAAWRRPWRQAAWLWLDTPDEADNRMSLDRVVTTIIDTEKGAKDADDNDRTDRQESITGIFHRLLKLPAELVEMIREDSAESLIWRYAAVLDRCQPLAGEDNQLTSMPLTDIAAWERGSPAQVSDNTADNPILRLMIDARGLRSIERLAALPPATHDRHSYKEAYVIVHQDEVKGVMIHFKYGLARLELPKKMKGLHIWDTPTPPSLTTDCSMLFQQILPRSRFQTVPLDRCDGITLLFEHGKVAVVHMHTPVTPMARMNFLSLDRTDIAWVYVPINRAAGDRVIAYGGRRAIKDVRLAEEEVEELSTYKAEKEAENAAKGEADDKDEDDEEEEIEGEEEWDNMYRNFNVDFLFRLKLAGDVSVGPMLLGPRKDTVLATSAPISLIFSSHESFILSVAGAYSESPALRPPLQLDPPFGDLPPREVTHANDYSSFLSTAPLDKPIRRITVFSDPVRDFDRGILIEYKDGGQRALGQCRIGWDDETEFEAPKCLCISRDSYTYKVPKPAARQPGTQSWQVFYAQCSDDISDGHEHEHDDENGIWECVPLGEPGCGRLELWFSSKTGRLTVIEDDEEHKAWRKKRNDASYTNHFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY49</accession>
    <name>A0ABR3YY49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="609"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="680"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="688"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="699"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="798" mass="88566" checksum="E74B8B7D920899ED" modified="2025-10-08" version="1">MDDPPSTPRVRARSRVACVTCHRRKVRCNVAQTGPPCTNCRGEDRECVTVPRKKHKPRRSKVAPLAPAVKPVAPDVAAESSPRARAPTTEPSSISSPSRLTPEADGRLPDDDATSYIGDNRGPRQSVYELCHPQTPQEARQQQTVEGRDKEGSNSSPQVRLPAWSSHELAYLRHEGAFQTLRPDLCDDLIRVYFEHVHFFMPILDAADVLGDYTRHGAAGLHPLLCWSMCLAAANFVPDDVLAKTGYNSRKAMKEVMYARAKCLYDLDRSTDKVTLIQAVLLMGFWYTDAYDHTGAWHWVGIAISLAQSLGFHRKPSRRSAGGDNNNIRRASLIRRIWWTCLVRDRWVALAKGRPMRIHDEDCDVPLPVLDDFAGDLEAAANPSFQRLLPAGGARSAAPLARMWLRLVSISALLGRIVRAHYRVQGPPPSLQDIDVFEKELRVCGQSDVSADIDMVEDENGDNHSEIADHLRLHANHVDLFYNATVAILYRPYLLHAPISLPPGAGPAWQKDVARRARSAAARTNDTLNTLIELDAIHQLKPMTITALVPAMQIHLFDSGKGATPLLRSLGKNKLGLCLLVLSHIRRTYWSASVIHRLFARAQQILQGAPASTMKTQSQSMTADEPTNSHDEQPPAEPRQHNLRGRPSTDTPTQPIYEEAQQPQKQPPQDDTIHTLNTYIADMPTPTPTLTPNSSTQPFLQSYLPSLPQNLPQGLPSSLSTNMDLQQQPQPPHLQQPDPGWWDEPATFLNVDLLLSPGFALSDDVCQTLFQSYDSSGQNVNVNAVTAGPSEMDMMYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY61</accession>
    <name>A0ABR3YY61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="3 8">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NMT1</name>
        <name evidence="13" type="ORF">Sste5346_006868</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="11">
        <location>
            <begin position="193"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="12">
        <location>
            <begin position="361"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1892785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="580" mass="64407" checksum="A76DF4FF28EA8346" modified="2025-10-08" version="1">MADNTKPAGSDDVPPSNVKGKEVAADASDSEGGSDDETNAPEEGASTTAEGGAAAPSKKKKKNKKKKTKTGTLADAESQLKKTIASLPANQVAELLKLNPAISQEIADKAGASSSSSAATGNEPKISAEAALAALKKLNLAEIMTGMAPSGKNAKDMASYKFWQTQPVPKFGEAEAGTGKKKSSVAEGPIQTLTVDQVPKERPPLVEGFEWDTLDLTEDAQLQEVFDLLSGHFVEDDEAMFRFRYSKSILKWAMMSPGWKKEWHIGVRATQSRKLVAFISAIPLELRVRKNVLHSSEVNFLVVHKKLRSKRLAPILIKEITRLCNVEGVWQALYTAGVVLPKPVSTSRYYHRSLDWQKLYEVGFSPLPANSKPQFQVRKYALPERTKTKGLREMVASDVDAVQDLLQRYLQRFDMAMEFTKEEVDHWLLDKKLPGDEQVVYTYVIEDDKTKKITDMFSFYCLDSSVINNPRHNVIRAAYLFYYASETGLTTPFDKSALKARLNELMSDALILAKKHRFDVMNALSIMDNALFLEQQKYGPGDGQLHYYLFNYRAAPITGGVDRNNQLDEDKLSGIGFVMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYN2</accession>
    <name>A0ABR3YYN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="98" mass="11298" checksum="009ACC3208AD3782" modified="2025-10-08" version="1">MGNGEKIYRGDWRCAVVARLLVKRRWQKLGNGPLAWQHGDLSEDSMEELVRRDADLLQGMRHGEYAPMQPRSRLTQASSDSQAEAFLISRPWFRLAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ06</accession>
    <name>A0ABR3YZ06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="714" mass="78423" checksum="EE72F4A32AE0FCE3" modified="2025-10-08" version="1">MVAAGSPDSLAAILTTSPSSSSAAQKRHQSPIRSYGALAFLNFFFHRVTRSGPKLLLYLALLLTSLLVLTQCLPSSVSNQIVSSTSHLWEFRPSGLGGSGGSSKTKPIPSPGDNNAHDALAGGGLRVVVFGENDIATSVQPDTANPLAGNGTSWTRELCIDLGCTTYISYVPVLESPRRSLSSNPLYGAATDEVVRDSKEKGPADDFTYVSEQYPIPWEAPDLYTQVSKFLEQPAPQRPPKETVWVLVSGMWDVWSLAAFPSKTAESYLTSMVFDLISAIEMLYDASHDVKSIAYSNYNAITLDDDIIIASGNQTANINNPEGATSQKSGLKWDDSNFEPFRVVIPLLFDPSLVPGWHLNRPNAPALHTKPEQLRNAVRLTKRWNDYVMEEMNNWMKKNVTFIHPGDREKFDPNAAAAAAAPPAAEAKPATESKAKVPNKLAPMGGAPKGALPNISAKQRRDNSRPNVPTLLRDGILFRMSDYLMDMIIDGQMRMRGIVDKKGFGKLPKDTSFLEVHRPCMAPEFVGLPTESNIKTEKIQFQYEEDEKHHKTALKGVDDPTHTLVAPGPPTGTEKVNDDPTHTHVEPGPPTGTEQPEHNHNPSLSHAKSRYRSKAKAKREEVPWKGPPVPPALPAVSQPQTPPTSPKLLVCEEPDRHLFYTPFSLGVRAIEDIGRLAASVVRASPKTRSAWEMDRHNSIENDRQPASWKEYYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZW0</accession>
    <name>A0ABR3YZW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mannitol-1-phosphate 5-dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_006549</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19661"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:61381"/>
            <dbReference type="EC" id="1.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannitol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.17" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00196">
        <property type="entry name" value="Mannitol_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023028">
        <property type="entry name" value="Mannitol_1_phos_5_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000669">
        <property type="entry name" value="Mannitol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002647">
        <property type="entry name" value="PRK02318.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002652">
        <property type="entry name" value="PRK02318.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524:SF0">
        <property type="entry name" value="ALTRONATE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524">
        <property type="entry name" value="MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00084">
        <property type="entry name" value="MTLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol dehydrogenase N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="215"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="400" mass="44789" checksum="22F55E7DC1C72721" modified="2025-10-08" version="1">MASNNSTYSKKAVHFGAGNIGRGFVACFLHNSGYEVVFADVNEDIINQLNDNKSYNVYEVGSDGTTETTITNYRAINSKTHEAELIEEIASADLVTCSVGPNILRFIAPVIAKGLDMRDVEAHATPMAVIACENAIGATDTLADFIRKATPEERLADHDTRARYANSAIDRIVPAQDADAGLSVKLEKFFEWIVERQPFAPQEPPAIEGVQWVDNLEPYIERKLYTVNTGHATAAYHGYNRKKRTVHDALQDRHIHHHVHQALEETANLITEKHGIDRKQQEAYVRKIVSRISNPHLEDAVERVGRAPLRKLSRKERFIGPAAELAEKDERCTFLLEAAEMAFRFQNVEGDDESFELGKIMSTEKPETIARTVCGLTENEKLFPMVVDVVKRVQADSMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z052</accession>
    <name>A0ABR3Z052_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein Mpv17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006387</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF50">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YOR292C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35774" checksum="8D5ABB78F2FC248B" modified="2025-10-08" version="1">MSWDLFSRRIARAANSKYIYGQIPLLHFIIFLIEMAIVARLTARFNAYYEERPVLTMMVTNAVLGGIADTVAQTITSMKQRQLRKGYEAKDDDDIALGRYNYRDRDDANKDSNSVAIEIHELAAGRTPNSTGQGIASASSSRHSTPDNVLPNYNNNNLPASKMLPPPFDFERLTRFMAYGFGMAPIQFKWFQFLSRTFPITKNTSALGATLKRVAMDQLVFAPLGIAWFFTVMTVTEGGGRRAVQTKLKDMFVPTLKANFMVWPAVQLVNFRLMPVQFQLPFVSTVGIAWTAYLSLTNAAEDVQQIKAHVPDAPGVRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z062</accession>
    <name>A0ABR3Z062_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SUA7_2</name>
        <name evidence="10" type="ORF">Sste5346_006407</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="9">
        <location>
            <begin position="154"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="479" mass="52142" checksum="AC22965D2F68CEA8" modified="2025-10-08" version="1">MRLALTLLSDKTDAHASDLTSCNLTPEEANKSINLVLDTWEEKTRRALTKSKRSKKSKKSKSLSTKSTTRKTKSPINKTRLVQTKLVAATRKPLKELHNKSSPETSTSPSTTSTTSTSSTAPSPSAPLSTPAKMDAATAAANAARDAYKENLDNIVMCPDCKEFPPNLVEEFSSGDMVCDSCGLVVGDRIIDSRSEWRTFANDDQGNDDPSRVGESANSLANDEGLRTQVDMRAANGRLAGKLNSINKKSQSEKLNNDLQEGFRAISGLVDMMQTSGIVGQTAMHIYKLAYEHGQLKGKPREAVIAGCIFIACRQCGVPRTFREIYAITRVTKKEIGRVFKSLESFLSKIQEKNPQASAAQGVKDYKASSSTTAEELCTRYCSLLGFRNTPRMEKISKALARKTTGIPDLAGRSPLSVAAACIYFASQYLDDPRASKDIASIAGVSDGTIKTAYRFLYNTRTTLVEPDWNGNLDNLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z068</accession>
    <name>A0ABR3Z068_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="437" mass="47134" checksum="E72A5016141A54BD" modified="2025-10-08" version="1">MFNRLKAHLFSGGAAGPASSGASASAGTTSTTSATPPSTTRPRYIPNLYPVGDTTIETYFRRLLSGPDTAESTSLSDLVREDVVAAAIHVARTDPSGRCVVPPADKFLPVLTRCITTVDFETAQFADEYMAEPEEAGISALQSPLLLQILVAVALKHRHKEMLRDLLKKHGENRPPSTIFEDAGCDAFRGSPFGSGVLDDPNYGKQAWLLLSDAGWAPPLTEEFDRPSLAINGIAADSDTARHTLTKMAEMSSADPAGALLHLDMLVASGLDPQPFTGYILDALVKDGTPAMVAHFLGVVTRKTYDGIPPRPKWPGMQSLLTKAAARPPNVEEEVLASDGEDPDVVDEGNAAANVSEDQKDKRNPRKERRRQRKRAERAQQGQNSEKNNGYGVLRVLVDIGGMDIHTSPGIWYKQGPDDEHPMALSRSTELPDGSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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    <name>A0ABR3Z078_9PEZI</name>
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        <name type="scientific">Sporothrix stenoceras</name>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AKR"/>
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    </dbReference>
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        <property type="entry name" value="ALDKETRDTASE"/>
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    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
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    </dbReference>
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            <begin position="20"/>
            <end position="281"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1894040.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="303" mass="33805" checksum="9BFC861A5BB0F296" modified="2025-10-08" version="1">MVQNTSLVYPLNDGRSIPAIGLGTWQSKPNEVRDAVTYALEHGYRHIDTALNYGNEKEVGEGIRQSGVPREKIWVTTKLDNTWHKRVAEGFQKSLTNLDIDYIDLFLIHFPCSTDPEDSTKHLPDWDFVKTWQEMQKLLDTGKAKSIGVSNFQIRHLEKLLSDPSCKVVPAVNQIELHPSNPSPKLLQFCKSKGIHCTAYSCLGGTSGSPINNSGPLMEEPAIVELAKDKSKTPQQIGLMWGLQRGTSIIPKSVTPSRIDQNFALDGWSLTTEEMDSISAIKSRFKVVQDGWMPIRVFLGDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0K1</accession>
    <name>A0ABR3Z0K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="568"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
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        </location>
    </feature>
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    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="835"/>
            <end position="894"/>
        </location>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z171</accession>
    <name>A0ABR3Z171_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="156" mass="16100" checksum="B291655DF59DB2FF" modified="2025-10-08" version="1">MSSSSSITAPTSTGVTSTVVSTSVASTGGPPAPTNTCPPGGNFMPDLKSLDIPHDVRVAVIPGTNTSAPWMVNCCYPNVPNLVDGCYLYCVVPANISNIDDFTNCLTRLNRPLNESRIVGFSNDAAPGHKSPTMSVTQLGVLVLVVSGISSLVFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2J0</accession>
    <name>A0ABR3Z2J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="321" mass="36593" checksum="A2500C024672C54E" modified="2025-10-08" version="1">MAALDLRVDSVDNCDDEVDNRTAVEDGTKIQKRGSWLKPPWGKKEKTSSVPRQSYKGATGYTDAKIATILRDFLQPDTKLSHLDVIATILPLIPANATASAEISSFSEMCVELAEQIPYHHPSQLKFAQLLSRLGKSPKFQSKYPIEGSSEILYDKYQRLREELADATGLDEDFPYDWVNINSFQAKLYSMGTFGATPGRSFVQLRYVFERESQKPEEGRLATLERNNEIMAATQWIIWHGQTMFSFIIYDDDIKDTHICPVGDIGDATPFQPRSLERWRYWARKFEKVETWTEATDECKGLSARAARLMHVLEENMVFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3D0</accession>
    <name>A0ABR3Z3D0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial DNA replication protein yhm2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YHM2</name>
        <name evidence="8" type="ORF">Sste5346_005805</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="21"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="110"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="219"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="316" mass="33969" checksum="E42ABB95802D679B" modified="2025-10-08" version="1">MTSLPVPAAPAAPQKLEKKPIKFSNLLLGAGLNLFEVTTLGQPLEVTKTTMAAHRGDSFASAIRRIWSRGGVLGFYQGLIPWAWIEASTKGAVLLFVASEAEYYARAAGGSEFVGGIAGGVAGGVAQAYATMGFCTCMKTVEITKHKAAAAGQAAQGTWATFMDIYRREGIRGINRGVNAVAIRQMTNWGSRFGLSRLAEQGIRNASGKSETEKLAAWEKILASSLGGGLSAWNQPIEVIRVEMQSKKDDPNRPKKMTVGNTFKYIYDTNGIRGLYRGLAPRIGLGIWQTICMVAMGDMAKTYVEKLTGEKVTAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3H6</accession>
    <name>A0ABR3Z3H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005336</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="174"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="525"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="701"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="568"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="704"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="730" mass="81420" checksum="A8D17770F4D23BCF" modified="2025-10-08" version="1">MGMPKSKKTVGLGNALMNDRFGNGKGKDQYRAGITRKNHATGEDYITNDRADAAWVKMRSITEQGAIEEFLSTAAYADTNFRAVKMNNSQIIHTDQKNPYLLTDAEEGRRLKLHNQNRERLTVPRRPQWDASMTAAELDKAERESFLVWRRGLAELQQNQDLLMTPFERNLEVWRQLWRVIERSDLIVQIVDARNPLVFRSDDLEDYVKSVDPAKQNLLLINKADMMTDRQRRAWAQHLTENKIAYKFFSAHMAKEQNELRQAEEEEEERRAAAGGNASKAPATPAKEEDDEKEETEDNKEEADELDTRILSVDELEALFLKHTPKTDDPTRKLKVGLVGYPNVGKSSTINALIGAKKVSVSSTPGKTKHFQTIELSPRVTLCDCPGLVFPNFATTKADLVCNGILPIDQLREFTGPCQLVTARIPKAFLEAVYGIHIRVQNISEGGTGVPTAEELLSAYARARGFTRTGQGQPDESRAARYVLKDYVNGKLLFVAPPPGHDIDPMDFNRELYDHKHLPEKRQIAMAAAAAADDESRVSSKSKNSATGRSLKRPSKKAAKKAGPNAWELEEDEESSDFTSDEDEEMDDDEEEASEEEDTDGEPMEDVAMTLPIREKQSTKSRDLDKNFFRENASGNRGIVVKPFSHKYTEQGQAELAAQAAEGGATVGGKKLTGRKARTMDALAKGLDAEDARAAAKIAADSKKHFKGGQRGKGKKKMPSNAIEAWGEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z401</accession>
    <name>A0ABR3Z401_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="641" mass="70374" checksum="6606CA36FC6B4F17" modified="2025-10-08" version="1">MTRLGPLTSQALGRSPYDILIPGDGEANPREPPQDYDERGRPVNAETKRINRNIVRSHNEVMHVIGVAEPDSLITAESESDNQLIQQHLEDMIGRKLWDPSRVIGALGVWGAEPLRQRALLYLRFSAYPPWSSPHFRQDYGANTLLDVVTSGVIARVADRYLRLASLERKSIRNSLWKRIGIRYVRLHLQVFTTLQRLSIIPAFPWLPGPLYFIPFSSESPIARPPPFPSSFSIGGWLEWGLQAALCVAPIAIFYGYTELREQLTHHLDYAIYDTLGTPSNPPLQRPISEFDPYTGERRLAGLPNVEVLPPRPPVPPPPQPQTQPTAPRERPAVPPPPADSQRLLSEGDENADTGRRNAIDGQDRQDGQEIMVGEASGSSETTPTQQHHHHRPSATPLPGSPTNPPQRRNTVSSSGGGAAADGYMSEEEEFELSATLISFDVEAGSAGDTPPNPWSAELRQSATVSIGYEGDGYGQYGDGDTGNGGHAPSLGTYLRGVYYPGVNAPFYSDTMLTRLPASIFAASASSLCAKLLLVDCEAAVVRILARGYRLQHGLPVDDLYDLGTVPFPFVPGGTFSLNATCHYAMAILMETAVKGVGVLVALGLAWLYRGSQQGWSFFRVVREKVNLYMTRREPYPVDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4B1</accession>
    <name>A0ABR3Z4B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005479</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046271634" description="CFEM domain-containing protein" evidence="11">
        <location>
            <begin position="17"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="12">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="126"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="194" mass="17918" checksum="93B6F2466B3ED286" modified="2025-10-08" version="1">MKSAVVALALAGAAVAQNLSGEPACASSCLISAISAAGCAADDVSCQCGPTETAIASLVAPCLISNCHSAAELIQAQSAGYALCSAYSKTAGAPASASATATSGSATTGSGSSTAATTTVTTTSASGSLTTTTKTSSSSSSRGIGSNATVTTGTKTTTKGGASGTGPSTTQSTAGAATLGAGVLAAFIGLMAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4U0</accession>
    <name>A0ABR3Z4U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40128">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40128:SF1">
        <property type="entry name" value="PHYTANOYL-COA HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="36114" checksum="5350CD82A654BD49" modified="2025-10-08" version="1">MTIDIEEPLYVNDGPLQPSDYAQLQPSDPATVPLEELRRRLRDDGYLFLKGLLPREDVLEARRAYFSYLEPSGVLKPGSDPVDGIFDASKNVAEFPGIGVGRLEDMAPQAQEFVTRALGAHSQPWYNQTLCKHPVLLEFMARFTGWGIENTLPLERTLLRNNIPQAKAIGVHYDQIFLRHGEPTSVTVWVPMGNVSLRGGGLIYLEGGHVLGRQFEDEFTEKAKVTGLSMDEAKSAFNRNMLSSGVLTEGPAAFGREYGRRWLVTNYEAGDVVLHTPYMIHASTINHDPDQVIRLATDLRFVDSSKPWDERWGEQFRLGDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5D9</accession>
    <name>A0ABR3Z5D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Haloacid dehalogenase-like hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051828">
        <property type="entry name" value="HAD-like_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191:SF2">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33224" checksum="06FAC0F8349D9E0B" modified="2025-10-08" version="1">MKRNLLLCFDAFGTLFRIKQPIERQYGDVARRQFGLATDVSDSQLRTAFRTAFKQQSRAHPNYGRWTSGMGATAWWTQVIEETFRPFVETVPPGLAPQLLERFASSEGYTMDERLPRLMRSLKERQSAYGRIVVGVITNSDDRVPGILSSFGLRVSPLRYGKETTVSPSPSTYDIDFHCMSYDAGVEKPDPAIFRAAEELLPRVGGVDADADADAGPAHWDKVYVGDEAPRDVTGAHAAGWNAVLVECEPAGENGNFVVRTLGDLPPQPLGRLFGAPSDAVVVGVDSAASFVEWLLKVEGDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5S5</accession>
    <name>A0ABR3Z5S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF153">
        <property type="entry name" value="AFLATOXIN EFFLUX PUMP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="55"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="544"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="553"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="583" mass="62188" checksum="B10AF8B50AD165D9" modified="2025-10-08" version="1">MEKNASPPRTAGRETIDTKNDPPSSPSKTPDIEAAMPPTALDETPALTKPKLVFLLVSVLTSMFLVALDRTIISTAIPQITDEFHSLPDVGWYGSAYLLTCCSFQLLYGKIYTFFPIKWVFLFSILLFEVGSTVCGAAPTSAGFIVGRAVAGVGAAGIFAGAIVCIVHAVPLEKRPRIQGLFGALFGLASIVGPLIGGAFTSNATWRWCFYINLPFGGIASAVIFYCLDVPDNANAKQPLKTKLKQLDGLGTAVLIPGVVSLLLALQWGGQTYQWDDRRIIVLLALAGVLLLSFVAVQVWKADTATIPPRIFHSRSVVAAVWSTINVGCSQYIYVYFLPVWFQSIKGSSAVTSGIQLLPLMLSMVLATIVGGFSTQKVGYYTPFAITGACLMSVAAGLLTTLQPDTPAGRWIGYQILYGFGMGLVFQAPNLAVQTVLPRRDVPVGTSLMFFSQLLGASLIVSIGENVLDNQLVKKFAGLPGFDPSLVTSGGATALLDELPADVRPLALPLYNEALRSVFRIGLVVSCLSVLGAAALEWKSILKKGPMGPPGAETEKAVPEEKKADSETTDKEMVGDAEKEVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z692</accession>
    <name>A0ABR3Z692_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase 2</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GST2_3</name>
        <name evidence="4" type="ORF">Sste5346_004888</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="110"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="274" mass="30643" checksum="51B146FF77E332C5" modified="2025-10-08" version="1">MADAPRPTGTIATKGIELLTLSTPNGYKASILLEELKDAYGIDYTWQLIDIGLNIQKEPWFTALNPNGRIPVIVDHDRNDLAVFEGAAILNYLVARFDKDRKFSFDPATEPDQVAIAESWIAWQHGGLGPMQGQANHFLRYALDKQSHYAVQRYVGETERLYGVLNTRLADRDFIAGTGRGKYSIADIAAIGWASGLQYAGVDITKFPHVEAWVKRCHARPATARGFTIPKEAFYADSNRAKRLEDPEAAKKEEASLSFLKDAQKQFNYKYTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6T7</accession>
    <name>A0ABR3Z6T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="494" mass="53400" checksum="26B17A8B01109989" modified="2025-10-08" version="1">MGNFETYDVPPPYSTYCSAPSNQYQAPACYAPPPGPPPSLRMATPATPSYNSNNPYAGSAYAGSPYGSRQTYNAIPEEYRAMAEMTQQPQQAQQSHPNTQLPSPSSSQGDEQEVDEIAAHYRQYMQPAPSPSAGGFFSSSSPSPSTALTRLIMIPQAYPASVLHPPAPFLRAYPPALASREIGISPALFVAIVDALNLCLAPPPPLQALNLVGQGVGLVPHHIAQGVSAGLGVVAGVGVAATRITKQKRFLAKVNADVFGPRGLAMEVVKDEAALGGVGLSQSSLPKAVPSTQVAGPVAGGTGLNAATQTRLTQLAPYTSPLSFDVPPAAVPTSLMDRISARQTAARLAKDAKRDDKRMQKREEKMRKLGDRRSSSLSSDDDDSGSSYSDGPAAIHAQFDARRQVAEQQGDWKEVAKIEKKRAKEIEDFQKKQRKHGSKHGGGREDKHQRKYDKKMSKMDRKEHKQDEKGQKKMGKLLWIVIRPVSERVEEYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7A1</accession>
    <name>A0ABR3Z7A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="126" mass="13859" checksum="F582475AA296F9B7" modified="2025-10-08" version="1">METLVAIRERYPAPQPLVLTGCHMTTEIYCFGHELSSLVKSRDNDAGFEFTACVNIIDLVLSMASDIGIRCNKTPALSKLLETAGLTLREVNIVEEIASGKFKDLAENKVMKQPRLRAGPAFSYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8J3</accession>
    <name>A0ABR3Z8J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ERF2</name>
        <name evidence="14" type="ORF">Sste5346_004782</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="568"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="479"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="248"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="701"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="296"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="728" mass="78351" checksum="EB8849EAFCDA63D1" modified="2025-10-08" version="1">MANPEPGARVASPPIPDDEHTFPTFPSTRSEAPGNAPSVISSRMTDIMSDDGKGPADVAGGAPSSRGQTKRTSTRLSQQPQFQPLRRGLSGKRSSAADSGSTAGLAAYGGRPVSSTQRSHVPSLTSHAFFHPMSSQKLQAQRGSVTRPRQSQLGLQQPLQAGESSTAAGASTQPQQSTSPTALARPISRGSEYTETVDRITANTSPTGGFYAAASLTDSVRPLHQQSQSRSGGGPADGLTIRVDKALNSGNVGSLPTPVRTPKSFRSSFMLPGKSGSGGESGVNRDIQGGEKLESVASTPQRSPSATSHPSNGTHVNSSSVQGDRRKIQSGGAGAAGNNGSVHADSKKTFVGRNYQFFQGNTVFCFGGRFENTKSRPINVATGGLVVIPCILFFVFSAPWLWHNVSPAIPITFAYTFYICLSSFFHASMSDPGILPRNLHVFPPIDENDDPLRLGPPTTDWALIKSCESSTAAMEVPVKYCRTCNIWRPPRAHHCRMCDNCVETADHHCVWLNNCVGRRNYRFFFTFVTSCTVLSLYLLAASLTQILLYSNREHVSFGAAIGHFRVPFAMFIYGILACSYPVPLMGYHLFLMARGETTREFLNSHKFPKKDRYRAYTQGRMFLNWIAVLCRPRPPTYLRFKSPHVEGDQRLFLETTKNVNAMRKARNNAANNGTDNSAIAADKNGNDLEMQHVNGVVGSGTAPSTAAGGGGEPFTPGFQGPVALRNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK5</accession>
    <name>A0ABR3ZAK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FRP1_1</name>
        <name evidence="16" type="ORF">Sste5346_004086</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="291"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1897350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="714" mass="78703" checksum="5A41EF1A8FFD28A2" modified="2025-10-08" version="1">MDMMMGTNMFQSTNMALARTYWYIVAAVVGAFVIVRIVNYYDSWVRLRARSATARQYPTKPMSAFLQIWATLTAVFREMSYPQLYVPVRYFTWLTPPPLGRVLMLLIYWGIIIGFMCAGSIIHDVNFWERIGFRNAWVTVTQLPLLYLLAGKSSVIAMLTGSSHERLNWAHRWIARTMFVTASVHGWHFYNEYAKAGMTSIFFEVMPMGKYGMAAWGLLLWSFVVGMAPLRHLCYEVFVIQHIVTAVVLLWVIYKHVPAYAEYNVWFAVAALAFDRVVRFGMLLWQNIKVRNPDRSRCKGGQRIGHEAQIRAVGDDITIVTIKDVHFKWRAGQHLYLWMPWIGPLEHHPFTIACAHQLPETCICNSIQLVVRKHGGFSKRLHDRAAKIRQQSGPGSGSRANTFTSFVTGPYGEPARWDIYETLVLISASTGASFTLPILESVLQADQNAICTKRIDFLLAAKKGDEIGYYVQRLHELIDKAKNMGIELTVSIAVTQDAKSLPALLRRESETPALLTEASEPAQQEKSYSSSSSIAATSAVATPAVPATADSGDIAEAPTSSCCQSKPADADKSALLVAPPAGPTTAEPGEITEAATSSCCMSKQTDIEKSALLVTSPAGPPAAGSTVLGIARRRPGSVASNDSHVQQMTTRPDIAAFIRNAVETTGGETSVVVCGGKSLVSRARNCVAKLSDERAVHKGTDAQGIHLHVEEYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAW3</accession>
    <name>A0ABR3ZAW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24124" checksum="13425A7FEB44761F" modified="2025-10-08" version="1">MTRTSIYGAGTLAFLGTTAMTVAATVIPNWVFYITYPTAGGSDPYWMSLGLHKSCKSDNTTPFSPLVSSAGASSSSYAAGTCRSFPSRTWDCGVEPEQQVFCTVWRTIGWLMAVALVAEFVTLIGFLVMLCGGRMRREYGWRILVPMVEGVALLQLCAMALVTYLMDHDDRFLVPGWHLGTSWTLCTVSWSLAALTGMGLAAAAYMLPPEDGYELLLNPEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB35</accession>
    <name>A0ABR3ZB35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="1">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003728</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF904">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="4">
        <location>
            <begin position="55"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="540"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="570"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="612"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="737" mass="79080" checksum="95168E41FE19F32C" modified="2025-10-08" version="1">MPDKGLSVATYAAGASLATIALVYVFAPTYFIDSAPPSSSGNPLAALTGRKTGVVGLANAANDCFINSVLQALAGLGDLRIYLIRETHRRKIDDAGVYSNAVPHDAEDSGSDGNGSGVPGGRPMPVWKVQGLQAGLVSKGLKDMIDHLNERPIYKKVITAGPFVRVLEIAFQQRISRQQQDAQEFLQVVAERLCDEYHAGRRARRYAKRQADREVSAGAAGVTGVAGPSVALNGNAVNEKLASIAAASNGDGQDSPSSDEVATSNALGVGSDFGSEEEGFPMEGKIESQIECLTCGFKPRPSEQTFCTLTLNVPQASHTTLSACFDSMLKTEYIDEFKCEKCRLVHAKQTYELELNKSKSESQRNELAHAIQKLQQAIDTDPERKPPDVALPDARHAPKRRIARHFRLVNFPKVLAIHLSRSIYDASNQSQKNSAKVSFPERLPLGSILNQRKYKLISVVMHKGSHHSGHYESFRRQTIAPPYSNPNTFQQSHIYSPSSSPAATTPKIGSSDASLGISPSSSRLADSPISSTAELPPSATSTSVDTNSSGSSPAQESLNLLPPKTNAAIGRSSRSSSLRGRSSSSAAMQPGPTSAPRDPTKEDDGNDTTGETASLRSITRSTLSRITSSSRSGSRAGSRSGSQNRGLGGRLSLRPGSKDSATASGVVSNGAPDKDKSKAPAASTHIPQPRHKKKKAPDRWWRISDEKVREASTKEVLGMQREVYLLFYELERDPYMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBB5</accession>
    <name>A0ABR3ZBB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Capsule polysaccharide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="498"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="64659" checksum="912811727B177EE8" modified="2025-10-08" version="1">MSDRFRLDNQCHEGIISKEWFNWTTAFLVLFVWRYLRQVVHLVSFWMYRPAQPLTNPKITRNDVTVIVPTVDPHNPHFIAGLTTAISNTPAKIIICSGVQIDVLAANEANKRAQVMHGVKYADTEICVLMDDHVLWKDTFLDYALPAFERDPKVGIVGTNKRVIREKVHDNLLHRVLNMVQCLYLERHNFEIRSSNAIDGGVFVVSGRTSLMRTSILQDPAFNHDYLNDYFLFGLVGPLAVDDDNFVTRWCIANGWRVKIQYCDETLITTSLGSAHKFTGGLKRWVRTTWRSNSTSLSSLHVYLTQPWSVYAVYLSLFTNFALFYDPLLLYAFAKSGLSSYHYVDNSQALDPIGYKMDGSLDYGTFVGADNFATTASANLFISFLPLICWIFAFKMVKPFAYFWRNPQDLWILWAYILFTYFHSLIKVNGLLTFYNAKWEGRDLASLNADLVRTQSSRGSGSLTSVPPLHPIQETTLPAHFTPGSRFIDVEPSMPSLVNMRLGSPPPPDNTNINRSSSDFPTPVDTDKGRTSTSNPNVNPFAYASPYAASLALDKLHVNDDQEHSNGTAQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC54</accession>
    <name>A0ABR3ZC54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051246">
        <property type="entry name" value="WDR48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021772">
        <property type="entry name" value="WDR48/Bun107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862:SF14">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11816">
        <property type="entry name" value="DUF3337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="141"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="640"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="754"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="973"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1076"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="706"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="762"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="789"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="981"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1106" mass="116221" checksum="71DCD4EF629E937B" modified="2025-10-08" version="1">MASKKTRQRISYVLEDARSLGHRLGVNGLAVDSENNILYSGGRDGVVCAWDLHLDKPTTAPAKPDDSASSSNDDGSKKSEPPARPHIQTAVSRAQTQAHTHWINDIALAQSNSALVTASSDLLVKIWRPREGDNDDEPAILGKHDDYVKCVASPGRQSTWVASGGLDRRICLWDLQGNGKILEIDVSGQEHAEKGSVYALRANHNVLASGGPESTVRLWDPRAGGKNITKFVGHTDNVRAILVNDSGDTIMTASSDQTVKVWSVTAGRCMHTLTMHNDSVWSLYSDAPDLSVFYSSDRSGLIVKTDVRGSLNDWDNGLSVAVAQEHNSISKVVASNGYIWTATSSSSINRWADVNTDEDTAAAAAAAQPPRPFSPSSETHRPHSSSVSTVKPAPRTVPADIPAKSILRISNTAIFPVAAGATPSSPVAGAADGAAGSPPGPGINRKGFEVVTNGDITPEAVEPVRQLPIETIEGNFGLVKHRLLNDRRRVLTLDTAGEVILWDIIACKQIRQFGKRHLEDVEPEVNTTEAVAPWCSVDVSSGQLTVVLEQYNCFDAEMYADELEDAGGEKKDGAVEFREDQRINLGKWVLRYLFAKLIDEEVRRDETHRAKLNETVEKRIQAAAAASKVSMLDVGLSPAAANGDSPKAGNVPPTPGIGLATPLPPASTLPSGVTPGGSEKEDYFSNAITSVEPTTPGPGALRPGQTPAAETPASTAAADAAAKEKEAAAATAAAATAGKGFGKKIRLGMSFKKGNRSASTSVPEKPAAAANVADANKAGGASGTGAAAGEDKSESASSHEKEVDDCFVGAVQRMHNDYEKQLTDNPDRLVVSRMHPCQPDEAPVLHIPAKTKVIIQEELTGGSIELYRGTVGGLGQPSHVDKIERVAPMWLGEAILANAAVIKESTKISFLLLPYRDELPALAAPDGSNRLNANRMLRVKKILAYVAEKLEQPTPVPAPAPAPVPAAIPPTVAEEAEEGDAAPAAAVADVPTPTPAAPEPEESLKAEEYLELYCNEQRLPHAMSLATVRAHIWKNSNDILLYYKSNGRKKLATAAEVAAAAAAAQAAAAAAAAANGESAASTEEAAAADDATPGAIPAAPAATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC61</accession>
    <name>A0ABR3ZC61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF2">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046500016" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="34"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="344" mass="37137" checksum="2FF66047C5B0D3D3" modified="2025-10-08" version="1">MLVKSLIAAAAFQLAAAQELMRFGCSQLTIDRIDPLVNPGDLPSAHMHQIVGGNSFNASMTPGSHDPPTLSSCTSCTYSEDFSNYWTANVYFRAKNGTFKRVPQVANLGLGVKAGATIYYIRGYQASAKVTAFKPGFRMIVGDAMNRKASAVPRGLCFRCETNMQQSPFGGAPCTGSDVPGFPKSPCGGGWRVTVTFPSCWDGKNTDSPDHKSHIAYPASGTFESGGACPSTHPVKIPQVMYEVMFDTRQFNNKADWPEDGSQPFFWSMGDKTGYGIHGDYLFGWKGDALQKAMDSKCAGDNCAALTRQANNKAVACTKNQMAHENIGDDKWLADLPGIDPATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCC1</accession>
    <name>A0ABR3ZCC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidine acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF195">
        <property type="entry name" value="ACID PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="61602" checksum="70CDFDAEEF6348B4" modified="2025-10-08" version="1">MTDTAIGRWAVRIVVGMGLFLAIHSLVLALVASEAVASMRPWPLSIDFAFFDSSDGDHVHADEFHNFGAPQEPDRPPPGSPWYAPRVSDLNNLSVALSPQTKGVYGFLFNDSTTPDGVPYGTYNWCNMPHVRADEYVVPPAEQKRSLVYVELVHRHHKRTPYASNGFPHEPYNWECDDARIHLYGDPVGNTEKRPGVAHYVPTFDAPSNPFLAAAPAWHGSCQFPQLTSGGLEDAWQHGVDLYKVYHDLLGFLPAMTDADAWSEQVAVRVTNNPITSQTVTMVLGGMAAAAGGGPILDTPLLAEAAGFDSLEPQYTCPAAVKMFKAITAASTDYNDNQGGSPVWAEHLEQLEPLFAKLDAASGVDPEDPHGFHESVDHYYDNLSARQCHGKPPVEGISQDEADTVFRVGQWEYSRMYRDDVRSLATSVGAWGVWVAQLAGHLRVASSGNNTDKVRYRHNVAHDGSLSRLLSILQADEMVWPGMGSEVVVELWKKEGEGDENEDKNATSSYDVRILFSGKVLRSSHPKLGLLDMVPLDALLTYIDGLVGVNASLLPAKCNGTSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCS2</accession>
    <name>A0ABR3ZCS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003547</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF187">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="466" mass="49286" checksum="CD5652D24F78EC49" modified="2025-10-08" version="1">MFGQLANVFGRRWPLIMSGVLFMVGSAICGSAFSMAAMIAGRAVQGIGGAGIGVLCEIVVCDLVPLRKRGTYMGAVLSMVGLGAALGPLFGGLFVRYSTWRWAFYMTLPMGGVAVVLLVAVLHVQYDRSQTVATKLASLDWLGNVFFVGGTVPILISLGWAGGTYPWSSYKVLVPLLAGLATLIAFVMLEGNKRLAPHPMVPLRLFRHSTSAIVFLLTFLHGVVTMWALYFLPVYFQGVLTMDAYNAGIALLPTILALLPGAIIGGLLLSKFGRYKPILMACFALIVVGFGLFSLLDAKSSTAAWVGFQVLESFGAGFGMAALLPALLAPLTDKDTALATATWGVLRSFGVLWGVAIAGAIYTNRAAQLAQRVITDPSVAAIFLSGGAYGAADVRFLDTLAPQTRAQVIAVQSDALKRSWQVAIAFGGVGLIAATVMKQISLREENDTEFGITEKNNAQNLETGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDN6</accession>
    <name>A0ABR3ZDN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin reductase</fullName>
            <ecNumber evidence="7">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TRR1</name>
        <name evidence="10" type="ORF">Sste5346_003409</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="9">
        <location>
            <begin position="4"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="35074" checksum="BC2E03BD4549B616" modified="2025-10-08" version="1">MHSKVVVIGSGPAAHTAAVYLARANLKPVLYEGFMANGVAAGGQLTTTTDVENFPGFPDGVMGQELMDRMRKQSEHFGTEIVSETVATLDLSVRPFKYATEWSPEEFHTADAVIVATGASARRLGLPGEDTYWQNGISACAVCDGAVPIFRDKHLVVIGGGDSAAEEAMFLTKYASHVTVLVRRDKLRASNIMAKRLLAHKKVTVRWNSAGVEVKGDDKGLMSALVVKDTKTGEQETLEANGLFYAIGHDPATALVKGQVKTDDEGYIVTTPGTTLTNIPGVFAAGDVQDKRYRQAITSAGTGCMAALEAEKYLTELEDDEEASKSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF18</accession>
    <name>A0ABR3ZF18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="89" mass="9495" checksum="3B2E510D303887F2" modified="2025-10-08" version="1">MSIFPTVENLPEYLANVEKLGKTLRVPAATLRLPKANGYAPELIYFDDGGVVSDLTAMAIDPYNNVLIGAAVLQYGGFAVCKIGHTKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFF5</accession>
    <name>A0ABR3ZFF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS52</name>
        <name evidence="9" type="ORF">Sste5346_003016</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="7">
        <location>
            <begin position="164"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="358"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="687" mass="76147" checksum="F66FE348F16C0DD1" modified="2025-10-08" version="1">MWLDRLSHSGGGPSPQNNGSRSGSPLPRRPSSASRGPYVTSQRSARNSSLSLISNDSTNSLLASRRQQNGSSLKQSTSANSVTGGDSRGQDAAALQLLGKLIGASPKDEKADDEDDVVITDEDLEADFDFSGLTLREIAWESPAQRRGSLQASRTPEELDKDQAKLEDLHKSIRACDEILNSVETNLTSFRNDLGLVSADIENLQSRSTALNVRLDNRKAVEKGLFPAVDDLSVSPDLVNNIVEGHIDEQWVQCLKEVDKRTASLRSSPNVQQSGDRQQGLKVIKAATDLLPLLDKLVLKAIERIRDFLVAQIKALRSPHINAQIIQQQSFIKFKDLFTFLHKHHAVLADEICLAYMNTMRWYYSNQFTRYAKSLEKLKMHILDKNDVLGHDDHSSRRSAAKMSGPPHDAFSLGRRIDLLKGPNQVALSSYMAEEDKATHYLEVPFRHFNLALVDNATAEYTFMASFFSPALSYATIAKHFNYTFEPTFALGKTLTRDLISETYDCLGILLCIRLNQHFAFELQRRKIPAVDGYNNATNMLLWPRYQVIMDHHCESMHSLASSGNSTILASGNAGGGGSSAAAASAAPHVVTQRFGQLLHGILALSTEAGDDEPVVTSMLRLRNEVEAFLTKYSQVCFGKDKRRRERFLYNNYSLVLTIISDVHGGKLATEQKQHIEALKTAFQEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFW3</accession>
    <name>A0ABR3ZFW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ring-14 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003119</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="403"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="56497" checksum="2BD62E3E8597CAFC" modified="2025-10-08" version="1">MKFAREFKAALKSGDFPEEWCKAAIPYPTLKKCLNKIRAEFQDMGLDADTLRQLLAAQAVSERGDQIPLAKYKFDVSDSAVQTHFTIFVDLEDGVVVDASLSPASRAFLQKQADIRRSSVADSSLTGETNGDGDSPMHGAAIDESDDDDSSPPSSLPSPPAERVHSHGARHKSFQRVEVSLTADSEFFGLIYRDMAELERIGHAEQVAITAEVVALGQEVSAVAQPERKKRNWFGGSTSEKSNGSTTTVAHHKYASDLTRWRELFELYLDAQVFFSTRERDHGKARTSAEASKQLDWFQEQVKRRGLLQHFQLAASLAAYQHFLLLNKRLYLNLRFRELNQTAQSKILKKFDKWTALGVSRTFPDALSRRHHDMLVESMARDVCARIAEDVVAVVPRLEDYTCPVCLSLAWLPVRLLCRHVFCVRCVIKMQREEQKFCPMCRGEVVMQADFDNLDVDLEKFLKLYFRQEVKEKQKANEIERGQELFGEEYKPSSCILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG11</accession>
    <name>A0ABR3ZG11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003054</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="323" mass="34742" checksum="44F203A99C21B355" modified="2025-10-08" version="1">MASQLVALPEVERLSPACIRILGGNPGKFTLQGTNTYLIGTGKERLLIDTAEGVPAWADALERTLAEEKATLSAALITHWHPDHVGGIGQVRKLAPGVTIYQSQLESGRLGAAPGEEILDIVEGQAFYVEGTTLRAVHTPGHTTDHMAFVLEEEGSLFAGDNVLGQGTAVFEDLAVYLQSLARMRALYSEKRGAAAGTPNRLYPGHGPVVEDGVAKITEYIEHRQQREDQVVRLLRSPDKAAAVAAANSGASSPPASSSGAADGKFPSSWTSMELVEVVYADVRRDLYPAAERGLIQILQKLEDEGKVIEDGRKWTLRERSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG58</accession>
    <name>A0ABR3ZG58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 93 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF3">
        <property type="entry name" value="BNR_ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045280820" description="Glycoside hydrolase family 93 protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41317" checksum="4E66DBE55ED9E975" modified="2025-10-08" version="1">MRAITPFLVSVASFAALIAAASPISTFNNKVIFTPPNTYTSPRVLYPRTVELRDGTLLATWENYSPEPPAVYFPIYQSTDNGSSWTEISCVTDQTPQGWGLRYQPFLYELLADVGTFKAGTILCAGNSIPTDLSRTQIDVYASTDRGHTWKFVSHVATGGKAHPDNGQTPVWEPFILYYQSQIILYYSDQRDPKHGQKLVHQTSKDLLTWDAAVDDVAYSEYKMRPGMSTVVLLPNNQYLLTYEYGGASGGFPVYYRMAADPRTFASAKEHPLAVGSTRPTSSPFVTWTPYSTVSGNKNGTIVVSANSLSQIFTNSALGDESKWEMHSVAQPAAYTRTLRVLENDPSRLLIMGAGHLPPSTTNAVSLSIVDLGKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHC2</accession>
    <name>A0ABR3ZHC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Microtubules assembly and stabilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MHP1</name>
        <name evidence="5" type="ORF">Sste5346_002665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="924"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1096"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1269"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="933"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1117"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1271"/>
            <end position="1288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1313" mass="141235" checksum="70DEAA85F1A727A7" modified="2025-10-08" version="1">MNSTMEHIHGIDVSWMTHGAPKDGNTPKPTSRRRNTLQSQSAPPPQSPVSPSAGSPAASSPRATPSASPVPIPIANAAGASPTQQLSSSLPAPSSSPRGRRPSWFSNISSKFSTNPGSSPPQATNTTPKQAELSVPRANIAKNAVLQHAAKYEGEGPYTPAPPKSSGQAGLLHVLRRLSTSGGNTGPAVKGNHGLVERRVLNVDRNRERCRLQELNQAKLRRVAFCVDVEIAPMPKYLDQDQVAKQATASVGPVPADKSQKKKTIEKSEGDALKNAKALLPEDPNQPKPTVNAASSLVVAATEASNPVVSSAKPVPVSANAVPSPQNIPPQVPPKKDANGTASPKSSSSPPASTSGDAQTDGAASDPNRKKEKKKRSEEERKMRKERKRRQAEANGMIPMEIYLDSDDSDTTGGRKSTPSTVPTTPRTQLAPTTNPVRIYRRCCQLRETPILKKVTEQLADPAVFSSEHGVVSKLDLTGYWLQLADLVTLGDFLAVVPIREVILENCGLNDEGLRVILAGLLAARKPQKKHIHLHHFHRHLHSNSSATHMGQTVPVTAALPHGEVHQGGFVERLVLKNNKIGVEGWKHVCLFIYMCRSLKAFDLSNVVFPHVLVNSKASHSSQTPDAKSAAQQAPAKQQFDVCQLLSQSIGERLGGSTLELLNFGDTGLSSEQLGWIVDGIIQSGTKRLGLAHNDLDDAGVQHIARYLASGRCEGLDLGGNDLRDRLEVLADAAVTNNSLWALSLADCNLTPASLCKLLPKLVELSNFRFLDLSHNHELFEIRPSATILLRRYLPMMESLKRLHLSDVAMTSEQAIAIAEVLPEVKELAHLNILQNPELTKLADARTEESQEQACALYASFLAATRLSKSIVAVDMPVPTNESSEIVRAMAKQVLAYCLRNVDRVTLGNPAALVVLGNAKSVPPTTDLPEVVSSDSTSSKTSLSKGDADYPDVLQHLVGHDATIIDVDDDIEAAPDDDYVIGGTGVAQALECCLKNRGPELTEGPPGANVVHDGDGALVEAAGASLPGPGKAKDMSKHLLQSARKIRLRLQPALQKARSMSAVDNQAYQRLLFLDNTLDGIIKRFEDEFPETRVSIDSGVSLSQPTADAKNGNRPHASSMDSGSADADVEGEGDTAAVFLSDGEDETDILPSRLSRSNSIMSLSSKGLTNEEGRMLRAGHRFRSGWFKHYNLLSGVDEIGSDPQHNHVLYELINEINDANINKKLAEKGIVRLFKEDREEMLQILKEQDPEHWDRFIESQEKARANKMIELGNPNPNGGSGNNNSVNGLSSSALSNALMAAAAENNESAILDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHT4</accession>
    <name>A0ABR3ZHT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SUN domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053088">
        <property type="entry name" value="Beta-glucosidase/SUN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005556">
        <property type="entry name" value="SUN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31654">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE ADG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31654:SF0">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE ADG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03856">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045320207" description="SUN domain protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="378"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="53805" checksum="0A9F7C24D2B53DFF" modified="2025-10-08" version="1">MKFSTVPAAIASALVLGVVQPALGEHHGHRVAHQHYGKRSVHNHIEAASLQERQPEAASQPEAHQNEKRQPQTIESLPALFTRDSSSTSSPRARAVSRSHADDIPKDLSKRAVCSLPNDPDLYSVPGASNGGWAMAPDVQCTAGSYCPIACVSGKVMAQWKPGTTYTYPESMDGGLYCGSDGQVSKPFPNSPYCVDGTGTVSAVNKCGSVVSFCQTVLPGDEGMYIPTDVTGTSTLAVPGPSYWASTAAHYYVNPPGTTGADGCIWGSDANPVGNWSPYVAGANTDSSGLTYVKIAWNPIFTGSSLSGTKPTFGIRIECSGSGCNGLPCEIGADNMADFSVTSSDSASGAGGADFCVATVPKGGSANIVVYNLDGSSSSSTGSGSSSSSALSTHSSSSSSSSSSSSKTSTTSTTSSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSSHKTSTSKTAGPTTFAGGIFHENGTVASTQSTKTGSVTGPTTGLGESGSSSTHGSAMPSTSSKSEAVNHNQGGAAVAGLIVAVVAGMWLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI11</accession>
    <name>A0ABR3ZI11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="36018" checksum="16FF3CB1642A92E4" modified="2025-10-08" version="1">MSTLQALRGMSQALFSNLFVTLPIPHPAPGLAEKIFIVTGANQGLGFEACKHLLRIGVGKIIMGVRSLDKGEVARKELLELSGRRPETLEVWNVDMASYESVQEFAKRAESLTRLDGVLANAGMMTTTFRRSEDGETTIVVNVIATYLLLVLLLPKLRACPSGSATFTVPNSSLHYVASLKEITPEKERTIFDRLADKSTSDMKDRYNVSKLLVLYATRALDTHLKQSVLAGGGQVIVNTPNPSYCKSQLVRETDQKPPDFVARTPEMGSRALVDGLLGGPETSGQFLNNCRVCPGASFVSNKTGAKIQSAFYDELIQKLDSIVPGVSKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIA0</accession>
    <name>A0ABR3ZIA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="310" mass="33515" checksum="B64E0564F8A57636" modified="2025-10-08" version="1">MNFDIPDQPKDGKTWKEVNKEHYDNLPEDTFKIKWIADMHRQIIEYLTTNSVWIGIPEGANADKGTGIRLLDYACGNGVISTALAPYASHIRGADISSTMVQRYNEAAEAAGFAPERMRAAEADLAAGSDPALAKAAEGDEFQGFNMALISMALHHVEHPVAVIQGMASRLAPGGKLLVIDLNLPEGEAATGPPAGHGHGHDHGHAHSHDHSHGHDHHGHNHDHAHDHAHAHDHSHSHDHNCDHSNAEAPGGLHTVVHRGFSEKDMLRIFNEAGLVNGEVRLNPTVSDLPPQMGSGKLRLFFGVAEKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIY7</accession>
    <name>A0ABR3ZIY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="7"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="436" mass="48348" checksum="D0C83CAB9A92F3F7" modified="2025-10-08" version="1">MSNPINIVIVGGGIGGLSAAVAISLAVTPTPKVTILEAAKELSEIGAGIQVAPNLTRLLVDRFGMADAVTKHAIAPRFVRQVRWEDGRELTRANLNENDRCERAFGHKYYYLHRVDLQGMLLARAVELGVDIITSAKVVSYQHIADIGGETVTCADGRAFSTDLVVAADGAKSRLSEYVLGAQVPVTPTGDSAYRATLPREQVVEDPDFASLNFEEGSVVWLGPLAHVVGYFVRGGSTYNLVIVVPDDDKERNEETWKLKGDPEKLRSHFAGWDWRLRKLLDKVDAENLYLWNLRDRPMLPTWLVPEAGNLVLLGDAAHPMLPYVGQGAASAVEDAVALAECLFHADKQNWALRRAIEVYQDVRRPRTDKMRMAGHKNRDYFHMIDGPEQEERDKKLATNSDVEKTPNQLDDPETLQDMYGYDVYSEIRRALGAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB8</accession>
    <name>A0ABR3ZJB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SMC1</name>
        <name evidence="14" type="ORF">Sste5346_002598</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="508"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="33"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="187"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="410"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="660"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="982"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1224" mass="140380" checksum="0B018FF11429A621" modified="2025-10-08" version="1">MDAISFVLGIKSSHLRSSHLKDLVYRGRVMETSKPNEDTPLQPDANGHTNGHANGDDDDDEAGDKKAGRKDPKNAWVMAVYEDDAGDTHRWKRTITSGGSSEYRINNRVVTAPEYNAALEAENILIKARNFLVFQGDVEAIASQSSQDLTRLIEQISGSLDFKPEYERLKTEAEQAIENQNFHLTRRRAINAEIKQYQEQKAEAESFQRKLNERDDAIVDQMLWKIYHYQRIMDDSSNQIQEHNENLAEFRRNLSDAETKLEEARAEQAAANKEASRVERRIRHKERDIEEEENKLIPVSEKVEQLSNDIALLKQKITSATEERDSQAARVQKAEKEIAVVEKARQQFEKQWKETLQKQGKDLSDEDRKEYHTLRSQVRAKCAVELADRDNIRRQLKSDEVTVNTIKGNVDSRQAKVTKLEAELETIKERHSTCQEDVRKIGQDVDGAKKTFNQAKSERVRVNNAVTDLEEQMQDISTRLETARSGMVQSRRETRMKEVVSQMRRIYPGVYGRVGELCKPKQKKYDEAVVTALGHDFDSVVVDTEKTAAECIQYLKEQRHTPMTFIPLDNVKVSAPNTAIKGISGARLTIDTIDFDSNLERGMAFACGGSVICDSMDVAKNIVYQKRLPVKAVTLEGFLINRSGTMTGGRMPDQKGNRGKRFAEEDVQNLERMFEKKRADLEKLPKPSHLLHHEKVLNDEMVHLEQRLRAARAELQAFEKNLNSKKKEVAEEKQQLREREVKHAEEAAKLAKTQNAVAKTEQAITKVEDKVFGAFCKKHGFKDVREYEAQQGSLEQQAAEKRSEFEVQLQRLKSTMSWEASRHDSTKTRVEQMERRSQQLTKDLKEYQAEKKQIEEVIAQAQRDVDKLRSNLEKMQEENSDTADNVANARTEVQKWQREIESRLKEINGLETEVQKNSAAKFALLQRCKMEQIQIPLEEGSLDDLPNEDQLLNQDPDAMDIDEGDDGVMEVAMNDHGIEVDFERLQAELKDGEDEERVEERLENKIAELTSELEKLNPNMRAIERLESVESKLREVDKDFEDSKKVAHRIKTDFEDVKNQRTDVFRRAFSYIQEQITEVYKELTRTEAYPLGGQAYLDIEAEGDEPPYLSGVKYHAMPPLKRFRDMEHLSGGEKTMAALALLFAIHSYQPSPFFVLDEVDAALDNANVDKIKKYIREHAGPGMQFIVISLKPGLFQDSESLVGVYRDQEVNSSKTLTLDLRKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK33</accession>
    <name>A0ABR3ZK33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPL11</name>
        <name evidence="8" type="ORF">Sste5346_002305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="6">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="7">
        <location>
            <begin position="64"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="172" mass="19808" checksum="5B17EF3D576EAC20" modified="2025-10-08" version="1">MSEKAANPMRELRIQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKISVHVTIRGPKAEEILERGLKVKEYELRKRNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMTRPGERVSRRRRAKARVGSSHKINRDETVKWFKQRFDGIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK46</accession>
    <name>A0ABR3ZK46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="814"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="814"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="857"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114640" checksum="971029848B026555" modified="2025-10-08" version="1">MADNSFNLPLQQTPDIESPSPTVTSQHDAYPPIAPSGNNNLNQNQNHSHNHHVAGQAHAHAAAQPMPPMAGATVYTPTSAPSSELNPRSCVTCRRRKVRCDKLMPCSNCRRAMVPCIFPAPERAPRRPRRKDPIALKPHQSSEREIELLKRLRKLEGIVEELSGQVEMEATSGKLPPSNSNSPEAAAGGSDGNAPRTSLDHSTTPSASSSWGQSPKLAHAGQGGTSGNSPGRLVGRNSSYGSLVKQTKDTQKQLGRLMINDYGRSRYVSSAFWSKINDELDELRAETQRISESDSELSDADSTPGHDDEDRPEADHHAFIFGFQSSTVDLRPLHPLPSQIPYIWQVYQENVDPVVKILHIPTTSKVIRDARTNLDNISPAAEALMFAIYYAAVNSLEESEIQTNFMAEKNVLVNKYRFALEQALAKANFLISSDLVTLQAFVLLLVLVRKQEDTRLAWTLTGLAIRICHSIGLHRDGTNFSNLSPFEIEMRRRLFWALCILDMRCAEDQGTDLTILEQGVDTLPPLNINDTDISPESTSLPPSREGATDMTFALIRFEICRVARRLHAIHSAMGPIEPGDASLTLEDRERMIHEVYDRVENVYLKHGDAQSNPMFWVAANIARVICAKMTLVIYQPVLFPGPANEAMSRDVRDRLFTACTELFEYSYILTMDSRTKQWRWLFQTYTQWQAVAYALIESGRRPWSASVERAWNGLNSIMSSTKPHDHEKMTDNASLFVPLKALYNKARKHRNAEIERLRADPEEVARLDKEDRSRLNPTMFSAYHGSLDGLQWRERWLRLVGAPHLIDEPTPIASTAVSSMNPSTQNPSTPIGGMSTNKAGGNLQMQQQLPQPPMAHGQQQGQDQQQQGETEPVSNDPMYPANKVLDNVFSNPTFEPADLYSVLNLGKNAAGGPAEVFGSFASADMPRQDMTLAQYSTDPSLAFTNPALAGDNGTGNPSTSQPEATPLVDAIVKDYPPPWLWTNDNMDNGSNQLPGMLADANDMKMDDIDENFDWQDFSQTLGGMSNGVWSSHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK57</accession>
    <name>A0ABR3ZK57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fructose symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HXT4</name>
        <name evidence="10" type="ORF">Sste5346_002172</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="57"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="554" mass="61400" checksum="EA87B4D5EA220940" modified="2025-10-08" version="1">MEHEKTKAEALEVVRGGGAQVNEMIEDMERLLEESGGLETGFFHIQFKDPKRFTWLLVAFASMGGLLSGLDQSLISGANLYLPVSLGLDTRQNSLVNSGMPLGAVGGALLLSPANEYLGRKNAIILSIILYTIGAGLEAGSMNFGMIVAARVILGIGVGLEGGTVPIYVAETVERRLRGNLVSLYQFNIALGEVLGYAVAAIFLRVPGNWRIILGSSLLFSTIMFIGMLFLPESPRYLIHKGRMLDAYKVWKRIRGIESAEAREEFFVMTAGVREEQTAVQEAAKNKRFPWMDFFTEPRARRALIYANVMILLGQLTGVNAIMYYMSVLLNQIGFDAEKANYMSLVGGGSLLLGTIPAIFLMETFGRRFWAIITLPGFFIGLVLIGISYQFSLETQLPTVEGLYFTGLVLYMTFFGSYACLTWVVPSEVYPTYLRSYGMTTSDALLFLMSFIVTYNFSAMQVAMGKTGLVLGFYGGIAVVGEIYQLFFMPETKDKTLEEIDEVFERPTMDIVRENWAGIKENMSNLARGRFGVVFSQQTKRRADLHDPDVSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKA7</accession>
    <name>A0ABR3ZKA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002392</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="37223" checksum="C5916EFD753E8199" modified="2025-10-08" version="1">MTKKALIIGINYYGQSYQLSGCLNDAANVRDFLVGEHGFEDNPDNVVVMTDADENKDTLLYPTRDNMINAMRWLVSDNRHGDSVWLSYSGHGGQTTDADGNNPTTEEDTICPVDFPETGQIDSATLYQILVDPLHPEARLTILFDCCHSGSACALPYVYRPDEEGNISVTFNDFVQTLQEGAQLVVAAQQLAHAPVMLSLDTLTQAKSFMHGVTGFAKDLAVVAETAIHGNPDDPNEDGLVRVDATVTVTTVKDVWMFSGCADDQTSADTNIAGVATGAMSWAFLAAMRQIPDGELSYVGLLTATRQLLKENYSQIPQLSCGGEYDLDQAIMVSHSLSLLVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKX2</accession>
    <name>A0ABR3ZKX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF24">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G03170)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16643">
        <property type="entry name" value="cNMPbd_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="79"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="282"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="201"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="413"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="818"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="215"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="825"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1108" mass="120370" checksum="2888565ED6D47A99" modified="2025-10-08" version="1">MRRARGPSPTSPFRALAHHHAAHNANNGAGGQGGTVSSMIRSFNVETNPTRPIRPSPLTASTFPDMPLDLVDRIRSFPLFVSAPDDFLAAIGKHLRPQIHAAHDLILTEGDDAKAMYWLVRGVVAVTSRDGEAVYAELTPGAFFGEIGVLMDVPRTATIVARSKCLLVVLKKEDLQQELPHYPDMEKAIRQEADERLTILKKKQQERRNVGTSGSTATPSTQSNAAATPSSSTTDPSATTTPTNSKKRKSPSPGVIEDPAVGGSALGSGYVNVRKTLKELPLFATLPPDILHFLGLSAQPKSFPPFTDIICQGSPGNDIYFIVRGEAEVVLQLPNGSVLEAASTFARPRLTQGQYFGEVASLGLSRGRTATVRSITSVECLMISGEALEELWRRCPPGLKNQVEATAHARYNQAAEGDNENENGNEPTVESTEDTSGPHEDVEMKDEPAFGSPWRPKTPSPVPSIASLRRHSVPNVTFTTPSKPSSPTKASHKDEAAETRQPSDPDPFLSVDMENLRNRRRNSLAPPVPQTESSASSPSSSSSLSSSSSSSTLQNLPALQASESNNSNSSPLKLFTFPPQTTPPPPDRKEKEKADKETTSIIEEFNGIKVEDHSQQQQQDTRGPFKKARRSPSAVRGSNGDRDHAPLSNSHQFPSEEALVLVFKQFDLSELIRLAGVCRHWRRVATTAPQLCTHVDLAPYNSRINDWSLSHIVAPFVGQRAIEIDISNCFHITDEGFQVLWQRCGRNVKAWRMKSVWDVSANQILDMSEQASGLEELDWSNCRKVGDNLLARVVGWVVPPAPPASSATNTKIVAISSSNNRSRQAQKQEQQRQQHQATAAKSGPAPGTIIGCPQLTILDLSYCKHITDRSMVHLAAHASPRLRALSLTRCTSVTDAGFQSWAPYRFTALTHLCLADCTYLSDNAIVSLVNAAKSLTHLDLSFCCALSDTATEVVALGLPLLQELRLAFCGSAVSDASLRCVALHLQDLRGLSVRGCVRVTGVGVDHVLDGCTRLAWLDASQCKNLASWVAAGGVARWGYDERQEAQRGGPKYNPTGWQPVSRRTLGLDPAFRQAAIAATPTPAMRGQRRRARQPVKFIIEKGPQDGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLX0</accession>
    <name>A0ABR3ZLX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="582"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="613"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="795"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="903" mass="97072" checksum="608464928F5B17AE" modified="2025-10-08" version="1">MSAREVENSAGAAAAPTSAPIRNESSSASTTARPTSSHTGPTGSERRRQQASSSSYHQEPQRYSAGIPASYQPLFGGAYDSDQSSTDRDKGQDNNADADTYAVLPDSYPAAYTLKWGPQQACVRTPLDIDDVVASSVAASASGVAVGKSSSRVNFLRRAWQCDVRSTATSASHKLFVLRDTGNEDTNRLLCVALDVDPAFMTAHISGQRYRPRDRLWRGGMGGNTNFSACYYVYPQTLTLTVGKPLPDGDSPRSSESRNRLDGAGPNAQRSAFHGAVGDVNEKVPALVDASVLAAAASKAPGRGPVNNSLIYDLKPKMRSNPVVMFCRGSLWVSPRANVLILDRDPSSTSLEDALLEALDGATGDPNAGQNLSTDGPQLPAAADILDNALSGLVYDQWLDFVDTLSVSNRESSYGRVNRKLLWSMSQYLEQNLTMARQCEKKFQQRQQQREHQQAQEPTQFSAEKVAQFYYNDQQFASSDDWKELLARLERIVALLPLQSRNPLAPVTIGNKTRFIASDTSYTVNCIPAADNGDITIRSAPEIGLGNGTSTPKGGTPPGGIIDPSHRPFSQTPQGQIALSRISYMGGILLPFSIIAGVLSMSDPFGPGDRLFWVFWVITLPITCFTLTIIYADDIRRAYIWRPMSHKSLQDAINRGEAVTASAAARLARAADRVIDKFSGDEDPEIETDRVSSAVRLVDSRDSEGRPARVRVTTTSGPGGPTFYRLAVGKEPNKAESPVVSPVQEQQDPLSGPGAVEKSNVHIPVAIHQARARPRFGILGPLRRVLPGGGFVTGQAESPASSSPSEQTSQGRFADVEPGLLSSPPSGETVVIDVARPNVDSGTADLFSRPPSGINVAAPGCPTILLSTQSTDDLQQVVAWRRQQLGWAGAFKTMVGYHLPKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMB2</accession>
    <name>A0ABR3ZMB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_001504</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the sal C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051565">
        <property type="entry name" value="Sal_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23233:SF84">
        <property type="entry name" value="FI23031P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23233">
        <property type="entry name" value="SAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="469"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="35"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="293"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="354"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="113"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="54812" checksum="398AEF586738C69A" modified="2025-10-08" version="1">MAVDSSQQRYLNNFDHMNSYSHHAAAAPHFTNPWATSSGASQHNAYSSMPQHPSLSGIDSLRHQHQQPHQQQSSQQQPQHHQTQHHQQTHHQLPQPVPQQQHHHQATPHHAQHSPISQQHPQQPPQSHHSQQQQQASRQSPIQQQQHQQHQQGLPRPPSQQPLPPAPSTMHRNGSTSMAPNASLPYGVAAIATTSAGYADSSNIAAYSAPSPIHPTTAYATAATPYDQMGYAPATTMRGAAPPGSAAAAFGLDAAAADVARRFSQDAAAAQQAAGDNRRGFQDALEASQGMMSLNSQDTPRPLGFPGAPGNTGPARSQRGSADSYGFPSTAHSTSSSVSSQSFGGFYTTGGSSIDSNSNISDYSGSDIEQVSSRHQGHHHQHPHTQILHGGVPQHHPAAHHAGVGAHTGHRQPFVGSVPPAPQSMMGQFSSKMTNSAQKKHKCKVCDKRFTRPSSLQTHMYSHTGEKPFRCEVPGCGRNFSVVSNLRRHRKVHKDLTPSEAGSDDHNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNH9</accession>
    <name>A0ABR3ZNH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FKR3</name>
        <name evidence="9" type="ORF">Sste5346_001232</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="113" mass="12058" checksum="B45D2829DE1E9AEA" modified="2025-10-08" version="1">MGVTKTTHQEGSGASPKVGDRVTIEYTGFLKDTSKPDNKGNQFDSSVGRGDFVTAIGVGQVIKGWDEGVVQMKVGEKATLDITSDYGYGARGFPGHIPANSDLIFDVHLKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNQ7</accession>
    <name>A0ABR3ZNQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="10">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SAM2</name>
        <name evidence="15" type="ORF">Sste5346_001502</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="12">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="13">
        <location>
            <begin position="131"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="14">
        <location>
            <begin position="253"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="397" mass="43428" checksum="6C7D32FCFDC6F4EC" modified="2025-10-08" version="1">MASNGTVVPSWQKHQTGTFLFTSESVGEGHPDKIADQVSDAILDACLAEDPLSKVACETATKTGMIMVFGEITTKTRLDYQKVVRNAIKDIGYDDSAKGFDYKTCNLLVAIEEQSPDIAQGLHYEKALEELGAGDQGIMFGYATDETPELFPLTLLLAHRLNAAMSAARRDGTLPWLRPDTKTQVTIEYKHDNGAVVPQRVHTVVVSAQHAEDITTEKLRSEILEKIIKKVIPAKYLDDETVYHIQPSGLFIIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYLGRWIAKSLVAAGLARRALVQLSYAIGVAEPLSLFVETYGTSEKSSDELVEIIRNNFDMRPGVIVKELDLAKPIYFQTAKNGHFGTNQSFSWEKPKTLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPP1</accession>
    <name>A0ABR3ZPP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding transcription factor cat8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CAT8</name>
        <name evidence="6" type="ORF">Sste5346_001105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15485">
        <property type="entry name" value="ZIP_Cat8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF12">
        <property type="entry name" value="REGULATORY PROTEIN CAT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="668"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="733"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="767"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="800"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="974" mass="106859" checksum="4F59A4254216265E" modified="2025-10-08" version="1">MPGILPMKVIKVGTSSQSRIAQACDRCRSKKIRCDGIRPCCSQCANVGFECRTSDKLSRRAFPRGYTESLEERVRQLESEVRELKDLLDEKDEKIDMLSKMHANQRRASISRNNALSPPSGSATSASPSPTSASSASDNLSRQSTSVSSASPGSTASGAAKSASPRNSIDGNSAPASKRDSKSSATPAVKEDTFRVQASPLVLGVENSDSYFMGSSSGRSFIDVFKRRMQEGGKSCSDFHAEAFLHIQGCYPLVEKVPASSMRAPPRLFSDRCVNVYFQEWSPLFPILHRPAFLRIYDEFVSDADKVKNNHKLAQLYLVFAIAGLSSDQPDVEQIAACEQQWQRALDAVLMDNTIITLQCLVLAILYCSMRADYKRLQYYKGVAIGLSHRLGLHQSQKRFSFGALTIETRKKVFWTLYTLDCFSAAILGLPKQLNDEDIHAEYPADTDDEYVTEKGFQPTLPGESTRLSAALALFRVARILAKVLDANYPAASTHELSLQKMASLESELTEWRDALPAHLTLTFRQEKPSTDVTGNRSPLLSLTYYYIRTLIWRPAVGSSLGTKAASAVMTVSEASKHIVQIIELLEERKMAFSMCMNKPDLLIVCGMTLLYQSMDLKSDSKMMKDTERLLNMVVKIADRTKAPGCYDFKRVAAMLVSIDDVPPTVTRTTAELTMSAPARRPSPGGSQRKGQQQQQQQHQFALGRHNSASMSETDLLMQQDKMRRMTMPVISAGVNSQGLDSEDRSRGRSSFDSPREHVQLPKQHRLSMSQAQMLSRMSQPQQQHNHRMMQKKSNLDFLSMSNSPQPSSPAQPRMSQQQFYPQMKRDQSPSSVTPADWEALLSSMDGGHMNVYDAIYGGPNIGLSAATDTTPASATSQSGDGWSPESWDLTGFTLADLAGTGGHGGPSSIPAPAQSVLSFSDESMSSVAGDDLNAADLNNLGLRGLDMAGLPYRSTSGLMGTGPEGYNVDGLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQJ8</accession>
    <name>A0ABR3ZQJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001333</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045754454" description="Rhodopsin domain-containing protein" evidence="8">
        <location>
            <begin position="29"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="9">
        <location>
            <begin position="82"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="399"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="672"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="770"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="682"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="779"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="791"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="881" mass="94902" checksum="520EA8B3262EF790" modified="2025-10-08" version="1">MSATTTAASVVASTLATLTSLTTDLATATSTTDSSSPTSTSRSGHAGHNGSHAGHRPNDSRRGVIIGVISFILPFTTAVVLLRFYTRHYLSGRAVGVDDWAMLAALVLAAVDGATMLLMTTQGLGRHMWTLTAEQITTYNMYFYMSIVFYYACLGTVKTAILLQYLRVFAVKMRKITLVALVLIGLWSTALVLVSIFACWPIRAFWDKSVTNPHCVADLPQWYANAAGNIATDILIFALPIPVLWRLNLPRSQRLSLIGIFGLGFFTCTISVIRITFLNLNGDDTYANVAAACWSIGELCCAIVCSSLPTLRPVFFHLLPGPLRHHYNNHSNNTNNNRNDTTRGGVGNGNNPNMYRPSSHHRQSAYLNAYANSLGGFTGFGHDLDHAFSHDGYRLKSVVTRDTNKPTNHDDDSTDGIRRSRTMIIPPRPPRPTSYYNPFSSQIHPAEQPRATEATDKVGLSFTTTSHLRSTSSLGSTDSDSGFHTHDLQRGRSLNRNRNRNTLRAARNRRLPTRGASSSGSDDGMDSDSDLDRYMQWAGRDYYQSQHYHYRKDQQDQLNKENNQEKKAITTAVAAAASPTTLTTSSTLVSKQPSLPTTPSHRLLRELVSELTSPRTNTNGGTGLNIRNSSSTETLGQAAREVRLNMLLPETPKSTATATDTHQRNKSGATFFLSDDEDDANHSNNTSSLSSGRSSSNSNNTSNSISPKKILGGQSLPSSAAPTRAHSPSPSLPPPSPPRSYSYSHLKRMAAAVADGVSTAVNAGIGVAGTSGSIGAGAIERKERERERGRSSSAGGLRAQIPKSPTAALAAPAIAPPMPSLNPADPLAIDRDAYLGLRQGTVTSIEATRPSTAEAEALGLTLPTGPGIQIRREVAQDVGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQZ1</accession>
    <name>A0ABR3ZQZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MCT1</name>
        <name evidence="6" type="ORF">Sste5346_000397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050858">
        <property type="entry name" value="Mal-CoA-ACP_Trans/PKS_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681:SF1">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="5">
        <location>
            <begin position="6"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="39890" checksum="55906ED17FA21A7E" modified="2025-10-08" version="1">MLTPWLEAFPITARDTIQEIDHLMGYKLSHIIQEGPGKVLTATPNAQPAIMATSILILRILEREFDFQVAERIDVTLGHSLGEFAALVAGGYLQFEDSLYLVRKRAEAMSSATQKARDEHGGDYGMVAVVTEPEYMEPLVAAVYKFLGYSATGERLTTDTASDKTPPPSQQVLIANINSKNQIVLSGNIERINSLMAQVRLFLGHDPRAVRLNSDSPFHSPIMRPAVAEIRRLLAGHSRVSGRESEDIVSFPGTLPCISNVTARPFNSREELKELLARQCEETVRWWDSIRYLDQEEGVRRWIGIGPGKVGRNLVGKEVGMRGKDLVKGGGVWAITDPTEIEEVLRGLEETESFVDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR27</accession>
    <name>A0ABR3ZR27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_001079</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17964">
        <property type="entry name" value="DEADc_MSS116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="120"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="346"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="589"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="622"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="674"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="704"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="725" mass="78822" checksum="B5ABC69667655DCD" modified="2025-10-08" version="1">MFRTSLLRAARLPRAASAASSASVVASLRLTTTRTAGLVQTAAFQSRVVPALSNVARFGRSYSTQTAAAESQDAPEAEGQDELVTKFADLGSVGVHKNLIRSLTQNLKYENMTKVQSMTISPALSGKDIVAQAKTGTGKTLAFLVPVIQRIIDAQPELASFGRYRPSASDIRAIVMSPTRELAEQIGEEARKLVKGTGIVVQTAVGGTQKNMMLQKTRREGCHLLVATPGRLNDILSSYDSGIAAPHLEALVLDEADRMLDVGFDRELREILKFLPDRSNVPRQTLLFSATVPKNVIQLARTYVDAKNFQFVQTISAEDVLTHEKVPQHVIPVEGYENIYPTMLELFDREIKAATEPGNDRMPFKAIVFLPTTHMVELTQRAFFQLRHSISLPPQYHIHSKLTQKGRTMAADRFRNSRTGILFSSDVTARGMDFPNVTHVIQIGVPPDREQYIHRLGRTGRADKNGQGWIIIAKNEMRSAGQILTDLPIQNVGGFECATHDLTTKGPEEAPFFTEVNEVLKQMPHDILVSAYMSFLGGSALGRSIQTTCDNINQWVKTSWGWDKPPAISRNDANKRGLTRVVGMNIGDEARRPRYSNPGEDEFERQFSSSFGSSGGSDRRSGGGGGFSRGSGGGGGFSRGSGGSGGFSRGSGGGGYDRRSGGGGFSRGSGGGGYDRRSGGGDRRSGGGRSPDFDNAYRATQRVRRTDDMFTGRSNNQKEDTPYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRN1</accession>
    <name>A0ABR3ZRN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="198" mass="22719" checksum="6A7BCB749AEC267A" modified="2025-10-08" version="1">MMALTIKPYLRVYTGADMHYRFNEEAEERYEDRDDMRYFDRYDYSDEDSDSDSDESDSIYGDSASTAFTSWQATVNTGNAVNNQAESKTDVRIEDGKVGDNAQSKAETAEVQTHDLSYYGYGDYDFGQLSRVTTMAVNIHDLMDPNPVTVTVEERDDDGDDEDEEEEEGEDEEAVEEADEADDLGMENRRWHCPEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRT8</accession>
    <name>A0ABR3ZRT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_000026</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="10">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="76"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="897"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1243"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1329"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1450"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1170"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1280"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="906"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1336"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1495"/>
            <end position="1504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1504" mass="164281" checksum="550CFB1BF6321537" modified="2025-10-08" version="1">MEPAVGHIVQLQDGTRGIIRFAGRPHFAPGDWVGVELEAPTGKNDGSVQGERYFDCAMGHGMFLRPKAVTVIGVAGNEEEEEEEEEDDEEEAEEPAPAPPPPRQQPQRPAAAPRPSVGATGPAARKSTVGGRPSSVYTGTSAGSRTSMSGDPGLTKRMSLNAPSPSPVSRSRPSSIARSPTKSPTKQLATGPSSTATSRTGTPSNAGTGAGGRLSSVTSRPRPSVGGSRTSMGPPAVPASRGGRLSTTSSTTSRTTTSQPRLGATRPGVSGTTTSRVGGRPSSIRVASGDSGNESAGSSRLSTARPTRGSIDGRIMSPQKSSDDEILSPQPKSPVQSRAAALERLTSGAPKAVAATSARQTAAAASSAATTTTRPAASTAAAHREIEDLKAKLRVLERKRLEDRDKLKQLDKLNADCEKYQGIIQKIQAKYQPQQQENTDLRKQLKEAETLLESVETMQAEHDSAMELATLDREMAEEQAEVYKAELDAVKLKNEELELEVEVLRGENAEFTQGMSPEEKASASWLQMERTNERLREALLRLRDITQQQEEELRDEVKILEEDVKELTAAKEQHESTKEKLVQAEAVVEDLRQQLDAAQAADDMIMDLTERNMSQAEQVEELKAVIEDLENLKEINDELEINHVQNERELQEELDFKAAVIQEQARRAGQQEEKLEEMEYGLTRFREVVTSLQSDLEDMRASHAVTENESEQLNSRSRAIMDLNMKLQLSAAKAQVKTIDLELRRMEAQEAEQHLEIVKLFLPDAYLQTDRNSVLALLRFRRLAFKANLLNGFVRERINQPAHPGHEDDVFVGCDVVDKLTWVSAMCDRFVSAISRCSTDNFARFDGALYELEPVERALNAWIDGLRRDELKEQTCAAELQRSIALMSHLAEVHLSAAANQQQQQSTPKANGFNNNNSSVSIGNDEEHDGQDLESFADNLHMRAVLMQSHLESASIALHTARGMVQRVIPPTDDEDDAAQYFARRAEAAIAQTRSAKVVAGKAVRALEELKSRSLSLMPDTLEAFETCEAASRGLAELAGRMGLDLFALLHEEGRTEPYTYAEVQTVVHNATLAVARGNNTDGGSADEDLFATYLAKLRAVATQVTDVAALSGDLSQTLEFDRPAAPWVVRGQEIKASKTVPVDAEEELRRLREDHAEARRVITRRDNDLGTAQLKIETLESKMRDAQNKASVIAELERSMAAEQVFTKQLKEDIEKQDRELKSLEADRDRWKKIASDASLLAGGGVDGTGEDGEGADGQLVAGGGSGNQAAARHSKERAVATAREMEALKAEIASLQAVVRYLREDSRRARLTEQANHAWLAEPLLQKSKRRQQKQQQQQKQQQPTATTRAQAVAVEARDVLGELVKMASAARVYDLGKQLPADRLAWRPAHTSPGYHSAKLAEDYAAWKGWEASVVRKARDVNSGAAVAAGAGGAGADFVSSKRLARKQHAASARQQQIRLPGSADDDKENNSPAGGVRVVGEGTQSWWRRQVHTDDPVYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY4</accession>
    <name>A0ABR3ZRY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Leucine rich repeat domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000072</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050715">
        <property type="entry name" value="LRR-SigEffector_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752:SF187">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="66284" checksum="3169053679C2DE2F" modified="2025-10-08" version="1">MSDEPSLPRMPPSRAADAIFGPNRKRGRFFDANGNASGSGSGPHHLSAHQLLMNNSSDPAVFSSDDDPALDNYALPDPNGSGVGGSRVRKKKRYVGAWFAQHPASTDSTFDEDPSLPEQRARGDRDQDEEQQEPHTMTLLLLSSPVRPRPSKKRRTFERQFDSGVWMGKEGIAEGDEGEGQEDMLEVAMAESPPPPSQSSTSSQLSLAPPPTAPFHADFPPPPPRQRRVFQRVPSLAVNSAEEKARKIVQDCIEAGDDKISLIGLGLTALSNATVEPLSGLVPIPVVTEDVAFEQRDPKLQLFLSSNNLMRLPGALFRLQHLTVLSLRGNGLTELPPSIGQLRNLKSLNLSLNKLQSLPAELLPLIRTYGQGGRLTELLVHPNPYFSPEAEHGEEEISRPTRHIGDRPTRVARSPVHYMDSWGKTWSSFTLEPAALGACNLIPTEDLTTASSPPTDNTAAATSRVPTLVSLAMAACYRTPQLPQLADLLPPEAPPRLARQLGKAQALRESGGSTCSKCSHGQSPPKPMVAPMTAWLEWWEFGKPDVNVTYSQAAPWSAGRQDTSGGAPQPVPLRENEIEVLPFMWRGCSWGCVPRVEEVKDVREDVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSF7</accession>
    <name>A0ABR3ZSF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000006</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="339" mass="36372" checksum="5C9293E37D8F21A4" modified="2025-10-08" version="1">MSAQVDPALVEALGLNPTTASIESHGGSGFSSTYKLTGEKEGKSVQYFVKTGSGSDAATMFRGEFASLNAIADTVADFCPRAHAHGEMHDRAGKHFLATDFLELGGSGSGSGNGSGSGRSFAAKLAELHTQCPTNTSAPEGKPFGFPVTTCCGSTEQDNTWKASWAEFYADNRLRHILAACIRNNGTDKKLSESVERLASTVVPRLLGDDHLKRSSERGGGPIRPAPIHGDLWSGNHGRGCIVGADGDSTGTEEVVYDPSSVYGHSEYELGIMRMFGGYSSTFWREYTALVPKDEPADEWEDRVALYELYHHLNHLAMFGGGYRSGAMSIVDKLLKKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUA0</accession>
    <name>A0ABR3ZUA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chaperonin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSP60</name>
        <name evidence="6" type="ORF">Sste5346_000273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="589" mass="62011" checksum="2C09222A778FC797" modified="2025-10-08" version="1">MQRAMTSRARASALSGLRTSTTTGLNLTQRRFAHKDLKFGVEGRAALLAGAETLAKAVAVTLGPKGRNVLIESSFGAPKITKDGVTVARAITLKDKFENLGAKLIMDVASKTNEVAGDGTTTATVLARSIFSETVKNVAAGCNPMDLRRGIQAGVNAVVEFLQKHKRDITTSAEVAQVATISANGDTHIGAMLASAMEKVGKEGVITVKEGKTVNDELEVTEGMRFDRGFVSPYFITDAKSQKVEFEKPLILLSEKKISAVQDIIPALEISTQQRRPLVIIAEDIEGEALAVCILNKLRGQLQVAAVKAPGFGDNRKSILGDIAILSNGTVFTEELDVKLEKATPDMLGSVGSITITKEDTIMLNGDGSKDMITQRCEQIRGVMNDPTTTEYEKEKLQERLAKLSGGVAVVRVGGSSEVEVGEKKDRFVDALNATRAAVEEGILPGGGTALIKAASQALNDLKPANFDQQLGIQIVKNAITRPARTIVENAGLEGSVIVGKLLDEFGTDFNKGFDSSKGEYVDMIQAGILDPFKVVRTGLIDASGVASLLGTTEVAIVDAPEEKGPAAAMGGMGGMGGMGGMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUQ9</accession>
    <name>A0ABR3ZUQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_000644</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="14">
        <location>
            <begin position="333"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="169"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="417"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1903358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="53559" checksum="F35AA9F34889BEAE" modified="2025-10-08" version="1">MNRRGLLVQQPARRSSGPSGNGASSSSSSIPLTRLAPDDLPPHETLELPLSDASVRKIAEITNRSSSLRVYDTHLKKSAELLREAVGNINETLAERSAQLEATAERRRERGGDTPASGEQSLIDSVARLKESVGGLTEKVERGARSTIDLQMELEDERQALGAMASRIEARAREDKQRKQERDEARAAREAEGGSRRRKRRRTGGNAKTEGDEENENGEEDEEGDDDDEDDEDITNAYQGPPAASALSILTEERAIRAANYDNMNAHQKYGLNNDYIAFKQMLHVSMYPDEDVQLPDASQWFNASGEPVPYGPAAGGANGNGEGAGDLDGADADEDLVVQREVISFKCPLSLVTMVDPYRSTVCKHTFEHSAISEYLRPAGGGRNAGMEPKKCPQTGCDKMYTAADIVPDTTMRRRIQQAAKRERLRQDAAEAATSDVEGDDGNGKGNNDPEHAQDVDDIVDASQFRRMTNAESEARTVKRERFQRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFY3</accession>
    <name>A0ABR3YFY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010345</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000134">
        <property type="protein sequence ID" value="KAL1887228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="7">
        <location>
            <begin position="755"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1039" mass="116852" checksum="F2487CB76280D7ED" modified="2025-10-08" version="1">MAGTLLCPTKPDWCNINVIHRNLLPPRSYFFLYRNQDEALEDRAEKACSVSLSGTWKFHHCQSPFDAPQNLTDLSTESTNWNDIQVPGHWQLQGWGKPHYSNINYIFPADPPNVPSFRNETGTYIRKFAVPAEFDGQQLRLRFEGVDSSFHVYVNGHEVGYSQGARNPSEFDISTAVLSSQENTLAVRVYQFCDGSYLEDQDQWRMSGIFRDVFLLAFPEAHIADFRVKTLLQDDFIDAVLDVDIETHGQGIVYLTLLDDKGEKVLRASKEAINGETAHFSLPVSKPRLWTAEDPQLYRLLLSFGERFVAQNVGFRRVEIKDGILQVNGRRIVFRGVNRHEHHAELGRAVPYDFMKADLLLMKQHNINCIRTCHQPSDPRFYKLADELGFWVMDEADLECHGFVTVDRVALSDEDKTKSFMERIDLIYGRAARWTTDNPGWEAQYLDRVVQLFHRDKNHPSVLIWSLGNESFDGCNTYTMSNKLRVLDDTRPIHYEGDRQAKYTDIWSQMYLDPDELIRQVTKVGAGKPLILCEYAHAMGNGPGNLAEHIAAFYAYPQLQGGMVWEWASHGLKTTDATTDSEVYAYGGLFGDRPNDANFVMDGLCFSNHTPSPGLTEYAKAIEPVQVHGGVEGNSVIIINRYDTVSLDHLACHAWLVGDSIKTQLGVVVIPTGVAPHTEARLSIPSLDSALANVDGEAYLQLQFSLRESTLWAQSGHIVAASQVQLRAPSSIITTERVPMTTVPPKVEERTSALVISAGTSTWTVSLSQGKLTSWVKAGIEILQPGQVLELGIYRATTDNDNRKEALEWREKFVHLSRDEPRHVSWTSNAKDLSAMVTIQSRIAPPSMSWGFTSTTIYTFSSDGSLHIECSGEPIEAIDFPPNFPRLGFSFSLAPFFQNVEWFGRGPGESYKDKKNSQLFGNWSSTVDNLFTEYECPQESANRTDVRWVKFLSSSDSGATALKASFGTQEGFSFAATHYTPEDLDGAKYPFQLHANKKDYVVVRLDAQHHGLGTGSCGPKTLDKYALKPQPFSFHIHFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHX3</accession>
    <name>A0ABR3YHX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_010116</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000114">
        <property type="protein sequence ID" value="KAL1887615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF11">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="62163" checksum="DA2922B8E6DD6E1C" modified="2025-10-08" version="1">MAITGLAQQYLPAATPATVVGGLLLLLALATMWGTSVPTSLRAIPGPPGLPVIGNILQMGSRPHRMFQLWANQYGELFRLKLGNDNWVILCSSEAVREIFDKQSAITSGRTPMPVASDVFSGGNRLLFLTYGPKWRKLRAIVHKLLTPKASETYKPSQEFEAKKLIYDLATDNVDEMAFYTHIRRYTTSVVLTSTYGRRAPVWDCDDVREIYQIMNDFTTAAAPGGYVADLLPALARLPTWMQWWRPHAVRGYKKQLVVWMKHWNRLKDQIREGKAPECFVKQFLETDFKKQDITEEQAAFVAGSMLEAGSETTSSALNSCIMYLAACPEVQEMANAELTRVVGDDRSPSYADEDHLPYIWAIGKEVLRIRPVTTIGTPHYTTGDVVYKNYVIPKNTIVCMSQYVLHFDPNKWNDSEKFDPSRYLAYPHKAGYYSAGDARQRDHFDFGGGRRICPGLHLAENSLYITLAKILWAFKIEPPLDENKKPLPMDLSDDAYEEGVNTLPKPFKVRFTPRSQERLDVLKQEWEQAQVDGFYLGNIKVDVNGMVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHY1</accession>
    <name>A0ABR3YHY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPN5</name>
        <name evidence="5" type="ORF">Sste5346_009879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="268"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="503" mass="57738" checksum="B50B59EF1385A120" modified="2025-10-08" version="1">MSDGALKPEKDFSKETAKVIGEAEELAKTDINAAIEKLTLLEKQTRQASDLASTSKILIAIVTICKDAGNWSLLNDQVLVLSKKHGQLKQAITRMVQTVMTFLDATPNLETKLSVIEAVRTVTEGKIFVEVERARVTKILSDIKKKQGDLKAATDILCELQVETFGSMSRREKTEFILAQVALCIEVGDWTQAGILSRKISTKYLSRKPAKTADQLEKERKEREKKEKENPEGVEGEPEEKEDDVTDLKLRYYEQQVILAKHEDKYLDVCKHFRQVLDTEAVEKDPAKLHPVLQRIIYFVILAPYDNEQHDLLERIARDTRNSQVPKDAELLKLFTVQELMRWPEVAKFFGPHLCESDVFDASTEEDDDDDEDDRKARQRWTDLRKRVIEHNVRVVSKYYTRIRMSRLTQLLDLTDDETEKYISELVTSKTIYAKIDRPARIVNFAKPRDADDILNDWSYDMKSLLNLLERIDHLITKEEMMARIQPTGKEPASGKGKGTTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI95</accession>
    <name>A0ABR3YI95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02233">
        <property type="entry name" value="cupin_HNL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047263">
        <property type="entry name" value="HNL-like_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43698:SF1">
        <property type="entry name" value="BLL4564 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43698">
        <property type="entry name" value="RIBD C-TERMINAL DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="129" mass="13967" checksum="8E59F304AF014F7C" modified="2025-10-08" version="1">MPASIIISGGKSPDTAAMQRTDTFTGQVWSQLVLSSGPTMAAGNNVFMPCSRTHWHTHEGGQLLHVTVGSGWICDRGGEPQRIKAGDTIWAEPGTTHWHGADKDSFLSHLAVGLGKTTWHEEVVDDLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIK1</accession>
    <name>A0ABR3YIK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="126" mass="14345" checksum="B0655E7DECE585D6" modified="2025-10-08" version="1">MTVEVPISSITRVGISNTILTITGFVVGMSLSFRSSTAYERYGEGRRSWAQLIFVSNKLARVIWYHVKTRPNHKEKDTLAKLTVMKLLVAFAVALKHKLRFEPYTDYEDFAGFVGHINMYAGEPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIR0</accession>
    <name>A0ABR3YIR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hsp90 cochaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">STI1</name>
        <name evidence="8" type="ORF">Sste5346_009995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="4"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="7">
        <location>
            <begin position="159"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="7">
        <location>
            <begin position="539"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="213"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="218"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="591" mass="65275" checksum="329F98CE9B333664" modified="2025-10-08" version="1">MATSDELKALGNKAIAAKNFDEAVEHFTAAIAVDPENHILYSNRSAAYASKRDWDHAFADAEKTTQLKPDWPKGWGRLGSALYGKRDLVKAYEAYQEGLKLDPNNKGMKTDLDNVERAMDAELRDGGKAGDGSSFPSSAADEMGGMFRDPALLGKLAANPKTAAYLSDPTFMQRLQALQTNPSNVQDMFSDPRMIEVMGVAMGLDFSMAGGMPGAAGGPDPADAPAAPTAAPAAPKEEPKVEEEPMEEEPEDEEAKAKREAKEEADKEKALGTASYKKREFDDAIAHYQKAWDLHKDIVYLNNLGAAQFEKGDYEATIASCTQAVEEGRALLADWKTMAKAYARIGTAHERLGQLDQAIDNYNKSLREQRTPDVVAKLRAAERRRIDEAKQAYIDPAKAEAAREEGNKKFKEMDWPGAVQCYTEMIKRAPTDPRGYSNRAAAYAKLLELPSALDDCDAAIKHDPKFIRAYIRKAQTYFGMRKYSDSVDACAEAERVDKEFHNGANAREIEQQQQKAFAAMYSSRDNETEEQTRERIMNDPEIMGIMGDPVMQSILQQAQGDPAALNEHMRNPSVRTKIQKLIAAGVIRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ14</accession>
    <name>A0ABR3YJ14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cupin 2 conserved barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000095">
        <property type="protein sequence ID" value="KAL1888309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40434:SF1">
        <property type="entry name" value="CUPIN TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40434">
        <property type="entry name" value="CUPIN_2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10373" checksum="F531B00F17CEF345" modified="2025-10-08" version="1">MSKSTKDSEVEVRSWGFGHVFTWTDGPHTYYRPHNHAGLTTHLILRGQLTIAYPDAADAAAKTTYGVGERLDVPAGMRHEVWVGPEGCTYVIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJZ9</accession>
    <name>A0ABR3YJZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyruvate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF13">
        <property type="entry name" value="ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="6">
        <location>
            <begin position="27"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="4">
        <location>
            <begin position="225"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="5">
        <location>
            <begin position="438"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="64681" checksum="FE11F034B1AAD708" modified="2025-10-08" version="1">MADETDYISDRPAGIDPQNAPAEMQWASDAIVEQLSRLGLNYIALVPGSSYRGVHDSLVNYKRNTNPEILLCLHEEHCIAIAHGYAKVVEKPMAAAVHANVGLMHATMAFYNAYCDRVPMVVLGATGPVDAAQRRPWIDWVHTSGDQGALIRPFVKWDDQPASLRAALSSLVQGTAITTTKPSAPVYICLDVELQEQKLVSQPTLPTTSRYLQLPRHGTSPDDVASVRQLLSTSQRPLFLFGRMNRTQMGWDARVALAEHYNALVATDLKQAAAFPTQHPLHAVDPGVFNTPRLCELVRAADVIVAFDWVDLAGTLKASLTENGVPEPAATVVHATLDAALHNGWSKDSGARAPVDMSIAADPDELVSSLLTASQGEEKRLTSWGQLATRVSPSPLSNTGDNDIISMHNLAEAIYSAIPSKELCLIRLPLGWKGGDLKTTHPLSYLGQDGGGGLASGPGQAVGSALALKDAGIVPVAVLGDGDFLMGSSALWTAARYKIPLLVIVANNASFFNDEAHQERVARARSRPIENKWIGIRIDDPLPNLSQNAASLGSTVLAGQVTSRKELASILEKAVATVKEKRTVVVVDVAVPPDGYSSALNKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL42</accession>
    <name>A0ABR3YL42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_009317</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="421"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="75"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="391"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="684"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="702" mass="78295" checksum="75B6EE115D31EAF4" modified="2025-10-08" version="1">MRNILCGGAKAIPQLDEKRKRFPVSLPFRRKSKQQNANNIPNASVVEPKSPVSNILVVVPAAAAVASPQNIWAVEPPQNPPVEEAAEAAPVRAPEPAPAPLPVPEAAPAPAPAPQPEPEVQAQPEAQPEAQLVEVPPEEAVAQMAQEDAVIIPDDDDALAAVAAVADNEAAADLARASFEENVKSACTMAVLAILPDICPIYLQETGESLAYDYESVISHILDKVDAGTPYPRRADLKRKRQMSSAADGGDAVNELERTIAAIIDDETLSAKEREERAIRYYNSEERRISNKATVYINLARTLICQAYPFVPHKHITSHLAEHHNCLLPALLDLDNHIIEKGPMGLSFVFKKTKTKLNPVYSIESLPGTIRIEETPFKKEALEEYLAALKIRQLRKKKREEEKQREIKEAANVRKAEREGTLRDCGCCCGDFPMNRMVHCNASELHWFCIDCARRMAENQIGMSKYELTCMSMDGCEEGFSMAQRERFLSLKTAAALDRIEQDFNLRVAGLEGLEKCPFCDYAAVYPPKEINKEFICQNLDCEIASCRLCREQSHIPKTCEEVKRDRGAAARLNIEEAMSEAMIRICNKCEMPFVKDYGCNKMTCSRPGCTNVQCYVCHQTCDYTHFDDTTRGGKEGNCPLFENAEDRHEIEVHDAEEKARQKVIADNPDVDVDLLKINMSEKVANDEKRRKTNEAARQARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM90</accession>
    <name>A0ABR3YM90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23388" checksum="0544C70E3F6E81E2" modified="2025-10-08" version="1">MPTTRKVPGGRQATLSFNHRVTKPSVQRQSAKEAALLTDKAKGVEKKEQKEDKKEEVEEKLEDKKAKAEVEQDEAPAEEEEEEEEEEEQEAEVAAPAIVARPQAEIVADAVSDAQVRRYWRAIEAEGIAKRVHQEGLDLGEKVLRHFDVSSQFGPCVGIERKTRWLRAQRLGLSPPIEVLAVMLKEEAKGVEGIQRSSFDDILNARVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM91</accession>
    <name>A0ABR3YM91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-trimethyl-L-lysine(9) demethylase</fullName>
            <ecNumber evidence="2">1.14.11.66</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_009219</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:60200"/>
            <dbReference type="Rhea" id="RHEA-COMP:15538"/>
            <dbReference type="Rhea" id="RHEA-COMP:15542"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.66"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the JHDM3 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.66" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055500">
        <property type="entry name" value="DUF7072"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF7">
        <property type="entry name" value="[HISTONE H3]-TRIMETHYL-L-LYSINE(9) DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23258">
        <property type="entry name" value="DUF7072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="8">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="9">
        <location>
            <begin position="553"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="835"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="318"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="738"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1267"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1317"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1501"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1687"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="739"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="780"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1317"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1357"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1436"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1518"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1706"/>
            <end position="1718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1765" mass="188342" checksum="93B241D2C2B09AF4" modified="2025-10-08" version="1">MSSKAISAHALGGEADTIAVASSLQPLDANVLASSTKAAAAASTATTTMPTTNPSAVNAENINPEQQASASASDNSLLPPPPPHRSHPSSSDRATTTTGLHSPPDSNNASKLDGSSDSELSDLDDEALAETFQSMQPETEDGDVDVDATLTSVTTPMATTAADTVYAASAVASDAAPTVFASAPEDSSTTPAPTEDDKPASADASAPAADDEDDIGEVEPDHFSGTVPVFRPTMHQFRDFKKFMGKIDKYGMKSGIVKIIPPQEWKDSLEPLDDLVKPIKVREPIKQDIMGSNGTYRQVNILHQRTYNLPQWRQLCDQSEHQPPARRGERRANADKPKPAPRARAAATATATSGGAASNASAKKGGAAKKGRGGRRGAGGRTQRHAADDDNASTVSEPRPMTPESQRGDDEKMVLDDDKTCVDSPQDTKHQSQHHDDREDADSTVMSSVEVEYPIKQEEDEDMADIPVAPRRMGFVRQGASANKTQSTSARRKYSKREGSAKIDEAAFKDWDYRMDVSDYTPERCEELERTYWKTLTYAQPLYGADLPGTLFSEKTDLWNLNNLPNLLDVLGTKVPGVNTAYLYLGMWKATFAWHLEDVDLYSINYLHFGAPKQWYSISQGDARRFEAAMKNIWPADAKACDQFLRHKAFLISPSHLQQHYNIRVNKCVSYPGEFVVTYPYGYHSGYNLGYNCAEAVNFALESWLPMGKIAKKCECAQAQDSVWVDVYEIERKLRGISTDDEEDLSDEDDEEEEDSEEEGDGDDVDSVAGLPTPPSGRLGGRRVKFPGSKKRKRTVRPSAKRRRALGEVDIDDADDDEGSRRLKKMRTRLWSGDSSPCCLCPNAFPDSELLPTDDGRDAHRLCASYLPEIRIETVDGKDVVKGVTDIQMPRMELRCLYCRLRKGVCLKCSHPKCTRSYHPTCAAAAGVFINEVDASSTSGESDSEHSHSHHSFEFTCRFQRSKRDRKLDSLALEKIERIRNAAAALQPGSICQMQLYRSDIFAGVVVENRPDEESVLVRIVPSGEEVEVSWKWLLVPDAADYRRLLKTNQADSASNKDLEGQQGQNASMCPTTGDVFVEGFTWKQFCDCEGTSFVPAPEQAKVDLDKANQLWHYLGKTSTDAKAQYTSDLANPVHDRKSNFLDSLPPVAIVTVPVNANPSPFVFTVPSTPVSVPNPHIQQVPGQTAGQSGIQPSTVEPRRSYSVIKPPYVPHTSPVVVASPAPPSITLASTAATAAPATTLASTVSPAAPTTATPTPAAIVPIPTPAPASAAPASAVPAPSAVAPATPASTAPVTATPALAPAPALATTPASAPTAVSAPASASVSPLTPLDGSANKIRKTSDGFVHPQQPASRTHQPGHRNRHRSASASQKAPFGPYFSMPKSGAASHKFPQIQHPNLSHGYATVSAGKPQAAGGAMSPPSGSTATTGGGNSVESSNLDPSSSNSSRRDSIIRGPNRVRKSSSGAASLAAAAAKLHKRSASSMSSVSSFGLGLGGGLRGLSRPSPHTNYIGPPPVPSSTASSPLLSAHNMNYNTRPGSSVSSYASYESIMGPGMSPHSPGGVDASPFIGSPGPQMGAFDFSTPSGSANGYQHPGIRPQFGAAWQQNFHAPLGSFAQEMDINFSPPSPMSTALGLPAGGLGAPANIVPGHQGSYLFSGPGNLGADSMLLGGSGGDFGGFGTISPPMIPESPMMSPTLEDTTPPDAGTTQSPAEQLKQQLRSISDSSLPSSYRLRCLHQPRRRHQSRSSLNRIFTSQLLDLSSNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMH9</accession>
    <name>A0ABR3YMH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1889016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="24466" checksum="67D7FBD0635C83FF" modified="2025-10-08" version="1">MVIRKLRKIERGTVIMWGAYMQLWDELPLLNQSTIESTGSPAAKGEEAPSEDQVQQWRNESAFNARCLQSGAGSWDNYAMRALASALESDDWPAPHLRCEILAATQWLIYSSPTLIRWAKENDEDFAQGEVVNWERDVQPGPLFHGREGLSVGRWNFWKERLESLLQSPPDHLFVEDVHGSMSLALERMKIAEKEDAERPEDVESGEVGIPNESGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNR6</accession>
    <name>A0ABR3YNR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="1">
        <location>
            <begin position="3"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="105" mass="11840" checksum="AF0233C9C0B0F24A" modified="2025-10-08" version="1">MAITRVTYFKIANAADWQKLIPMYRAMPTKALKNGKPYIRSVKAGPAKDDPRSQGYTFAAISTFDSLEDMRYYDDGCEAHAELRSYVQSVHNGAMCVYFEDAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNW4</accession>
    <name>A0ABR3YNW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA ligase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF2">
        <property type="entry name" value="ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="7">
        <location>
            <begin position="405"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="746"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="896"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="749"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="948"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="968"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1010" mass="111806" checksum="C08AFBEE265F0999" modified="2025-10-08" version="1">MPFLFSHVCDLFEQVSDLPPAKRNQPRAVNQVVNAWFSKHRKEVDAMIVPPSTAGSTSPTAGPTSTSPTITGSSASALLSTLLPDRRTDRVYALQARGLQRILIRALGLGSSRIPELSRWMRASDHTTTGPVDLADCVEAILQRTPNSIPVVPVTVEEIDSILHGIAARCRFSAPSIRGNRKWGPSSKNKWAAPPPTQDALSRLYQRLDPVGAKWMTRLILKDLRPCVLDGTAVARAFHTALPQALQVHADLCAAVSSLSESFDGRIRPRLGVKIGRQQWAKGRSIQHCIAMGGPQRMSCEHKMDGEYVQVHVNLTRGADDESCLQLFSKSGKDSTWDRVNLHSAIRDSLRLGQPDCPIQKGCILEGEMLAYDERACRIMDFDAIRKHVNRSGSRLYCDPRADGTQEEHEHLMIVYYDVMLIDDESLLSTSHEERFRRLEELVTRRSGYAELVQREIIDFRAHTAPAQLRRAFARCITAHLEGLVLKPLKDPYFDLQGPGSGTTSSTNLEWPYLSSYVIKLKKGYIGGFGEVGDFAVVGARYDAAKAREYPADLPGLKWTHFFVGCRETPKPGQTRPRFVVTNVVTLTAAQMATFLKHCRPRVVPYERKKKGAKQLSKFEEDCPFDLASLEPGLDDSKGGPTDLFTDPPVVDIRCFSFHRQGYGRFWSPRFPSVVKFHFDRTYRDTLSFDDLQSMAVEAEARTTVYDDDFFDGTEDYADGSVDDDPDHAHWVAQLKQADKRHIAMDAETSQSQSQSQSPSQTTTARSQSASVSASTQRSQHSTSLGVPLIEILEEDEDRSHNYHSQLSIVTVKTYKDERVARVKPKPAVVVTVIDLTGDSQETETGQPGSTVESTVESTVEVVDVEDVAPEPEPDIVEAPSTPKRATSLPLPLFRMSPATPITPKTPPHISSSPLPPASCSPIDFVSSLTAPSPTGGDGQESHDSHSSFDSLNSFNSLNSVTHRPKITTKTESLPNDSPSRKRMRGWDVDNSLCPAVSPPQLKWARTFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP86</accession>
    <name>A0ABR3YP86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Catalase A</fullName>
            <ecNumber evidence="5">1.11.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CAT1_3</name>
        <name evidence="5" type="ORF">Sste5346_008795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF26">
        <property type="entry name" value="CATALASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="4">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="446" mass="50138" checksum="37A2397C9E98FFC0" modified="2025-10-08" version="1">MAEGQPVVDPSVSITLPMFGGGAHTTLGDTLLIETLAHFARERIPERVVHAKGVGAWGEFEVTNPEISKYTCAKFLDTVGKKTPILWRLSTTGGEKGSADTVRDVRGFSVKFFTEEGNYDIVGNHIPVFFVRDPMRFPSLNRSHKRHPATNRPDDTMFWDFHVNQPESVHALMHLFGSRGLPDSVRRVPGFGVHTFKLVDNSGNFYYCKWHFRPEGGTTSFATAADAASTASQNPDYHHKDVWDAIAHGDYPVWKLYLQIMRPEQAESVGRALFDITKIWVHRDFPLIEVGKMTLKKNPQNYFAEIEQAAFSPSNMVPGVAMTPDPMLQARMFAYPDAQRYRVGVNYTQLPPNRSIAPVYAPYERDGITTTKNYGSDPNYVNSTLSPGVPARAVTQIRHLESIPRTSSFGLNEIPVGEEDYVQPRQLWQRVFDDAERMKWVGNCAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG0</accession>
    <name>A0ABR3YPG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ERCC4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_008398</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EME1/MMS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20085">
        <property type="entry name" value="XPF_nuclease_Mms4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033310">
        <property type="entry name" value="Mms4/EME1/EME2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047521">
        <property type="entry name" value="XPF_nuclease_EME1_ascomycetes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077:SF5">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MMS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077">
        <property type="entry name" value="EME1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="15">
        <location>
            <begin position="577"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="12"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="171"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="466"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="722"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="504"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1890244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="927" mass="101354" checksum="AB31801C4B46C10E" modified="2025-10-08" version="1">MAGDVVILLSDDSDSDGAFVTPHPVTASPANNRTSGFSTSQEATRLPPPQLNLPTPALAASATRRIVDIIEIDDTPVPPRPSHRPKAPPAPVPPGFWSIPGDGFIEPSSSAAVAAVSSPRPQVLNQTPSQPSVSTRLPPPLSAYRSPLQESIRERAAKAILERLQANQSLQVNNLSSPMPNNHVFDDDDGLDDNDNFGRDRPAKRMRLSSGVGSHDAASRPTQRQPPPPSVDAIDSPPRRSPPRRSLPVQPISSPVAPLNPQRLSRFAHTFNYFDDDIDDIEDDIGDFPAPALQTRPAPAPVRPAQARQPCPPKANAECIDLLSSSDSEHEQSRLSTRLPAIDSDFVDIDDLIANPSPRARKQQQPQSQLQRQSTTQWPTGHMREPSDEIVLLSSPSVVSTVVRQRSRPAVIASAAIPPRRERPLQRSVSEAHGHASHAFVFSDEEDDEYDAATADALLAEWRASRKAAESQSPTKPSVKKAPARTTARRPPAKRRSSFDEASATDRQKQKKLEAEEKRKEREAERERKQKEKEIDKERRKTAADMAKEKKAKEKAEAAAFNDANKSRVDKAVAAPEMIVRLPSTLPQATKEVAQAMLVEVKASHEEWTSRPVDNVVTWRRKTSNDYRPDLGHWVPVPTRIEDEKHALVVLRGNDFVQLVLARDGDPDIRHQTGGHDLDSHVAAMKRAFAGHTIVYLIEGLNAWKSKNKTIRNRQFVAAVRGGSDAGGGGASAASTSSSTTTTVRPSQRLGRRGQKQAPQHLDVTLVEDALFDLQIEHSGSSDGSGGGVLVHETASSLDTARWIKVFTEQIAIARYRQQREELYAAAASFCMDSGQIATGDDAADTFLLMLQQVGRVTEAIAMGVATRYYTLPKLIQGFADDGPLALETCLRSRNRNGALSDRTVGQALSRRLYKVFTGRDPESTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ61</accession>
    <name>A0ABR3YQ61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="8"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="352" mass="40840" checksum="C5868C78E9E2F435" modified="2025-10-08" version="1">MEYTAADDYYGILQVTPLACKEVVKAAYKALALLRHPDQNRDDDTDATRQFQLLSEAHEILSDDLRREAYDRDVYPAVRARQGQAWAPQPPPFSGPTQMPTAGSSPRARPQPSPRKPPPPQQQPQYGYQQPSRPRQPSTPRTTTRPDSPRPQEPTFYQESPRKPRPPPRQSSWQESYQNPPHYPEQFYQQYRPPTPEPPEGLFQKLKVYNSDIKKLNNMRRTLSDKMNEAGWAHNTFQNLQLPNFQLFNPPAHVPRDCQLHDATIRWLRRRAGSRDTMERTWMLQQMLKLEAEGAVMVAQYSDFYYAKEAALRECEQMRDIYLRPQNDPPPPPPPPQADTGYFSGYPPDTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQQ7</accession>
    <name>A0ABR3YQQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="614" mass="62470" checksum="74243818EC754783" modified="2025-10-08" version="1">MAAQQAPRNQAALDMLSQTLGEVLIHAGKAIRAQAKNGRKVVGALSAAKISDANTQFNSTLDSIETDILRAKATLRRDLDLLRAQKSVAASVSAAANNNTKKESTSNGTPAFSQAPAAAMDIDMEELPKPAAAVKIKTEPADVSSSNSNGNGSGNTPAGGAAAAAAMAPFPNMDLDSPMATASLATLGAVSMQASSSNKSGAPTPQAGPPSTKSPAVKKETIVRPPQFGKPNASAPSSTAGASPANAATNKAPARKRTVSPAAMRVPSPAAPRATASPAATKVPSPVLVKSAAGSPAIGKASPVPTPVVGGAGGANKAISLSSSSSPSVTATSPVLTKMSAAASAASRLTPPLKSTTPVPAPRIPTPITAPAVKPPATTAVVPPAPAPAPAPAPAPVPAMEASSNDIDMDNFFDLTGPSGDDPSNADSLGFTNMHFSLVPVETDEQAKPVQQPPMTSQPPPVQTAVPVPQIPQAASQPHQQPSQQQQQQQQMDDSEFDVEKFAADAAQNLMMDTDFSSAPPAQQQFQIQKQIQLQQQQNQPQQQSQPPAQQQASNDLLMPDAGGAGLPGADGDDLFSFINDGMEGLVDDPTTNFDELYMGGGDSIDIDDYFDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR04</accession>
    <name>A0ABR3YR04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="45"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="583" mass="63201" checksum="660D4C6D392BFB11" modified="2025-10-08" version="1">MADTTEKDTAVHGEHVETASGAVTMSEAEQAVYHEEEGKVTLKTKLAVFSLIFMYESYLFTLIMPAAILTYINADLGPDSNYSWIAISWNLGAAVIVTIGGRLSDISGRRWFLLFGAGAGVVGSIVGATGQSINQMIVSGVIFGVGGGFQEMCFACALELVPNKYRFRTMGVMIMANHFSSFGPLIGYAFVAYVKPGWRACYWWCFAWEATAFILLFIFYHPPTFERKHEDDHKTKLDLLKELDYVGLLLFSGGCLIVLLALSWGGGQYPWKSAGVIAPLIVGFASLVALGFWEAYMPLKYPILPPHLFLQWRKFTSFLVVCFVAGMLYYSMNVIWPRQSALLWIPANNTITRGVYSNLVSFGTIMAGWYMIGVAPWVKHERWQVISFITIQTALIGSLASVGINDKIQAIVTVVIVSMTNLPPSPLSFGMVSLHLDDQTDIGVAVGLISTFRLLGGAVATAIYTAIQTTRYTQLLPGEVNAAAESSGFNGSFAALLIAAKTNTAAAYAKIPGISNATIAATELAVKEAAAMSYHLVYFVAIAFGALSIAAALTIKGVEESSRTGHTAVHLENDVHEGLKTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR07</accession>
    <name>A0ABR3YR07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dihydropyrimidinase</fullName>
            <ecNumber evidence="6">3.5.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008058</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16121"/>
            <dbReference type="ChEBI" id="CHEBI:11892"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15901"/>
            <dbReference type="EC" id="3.5.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050378">
        <property type="entry name" value="Metallo-dep_Hydrolases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02033">
        <property type="entry name" value="D-hydantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647:SF1">
        <property type="entry name" value="COLLAPSIN RESPONSE MEDIATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647">
        <property type="entry name" value="HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="7">
        <location>
            <begin position="56"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="55935" checksum="8252E7EA2B20F0AE" modified="2025-10-08" version="1">MGSLAPSPSFEVLLRNANVNGAFVCDIGIQDGVITAMGMHLPSSERIAVIDCEYAVVTPGGVDGHVHLSQDKSPRAKEAGYVAADTIETGTRSAIAGGTTTVLLFTEQSRGQSVAEQVAKYHETAQRIGSYADYGFHAIITDPTTKVLEQELPVLARSGGITSMKLFLTYKHMRLSDAQFLRALKAARELGMVALVHAENGDLVDFFTEQLESLGLTQTQYKAVAHPAAAEAEAVNRAVTFSTVMDTPMLIVHVSVKESMEVIRRAQASLKPVFAETCPQYLLLGKKRLDEAHFCGAKFICSPPLRSDPDDIEAIWRGIVNGTFTIFSSDHCPYRFNDPQGKQLGLTNNEDGTITEKFTQVPNGLPGVETRLPLLFSEGVLKRRCIDVKRFVELTSENPAKLYGLYPKKGAIQIGSDADLVVWHPQSTFQPRKLSHARDLHDACDYSPYEGIEFWNWPRMTLLRGQVVFKEGTVLTKNGVGRFVPRQGCEMPYIKRMEGKWDVLKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR29</accession>
    <name>A0ABR3YR29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="153"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="260"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="46596" checksum="088D1A0E28CFE9C5" modified="2025-10-08" version="1">MSSPSLNLAPFAEPAWLATLASPYYTNSHRQLQKSVRSYLETNVFPFVEEWEENGQVPAEAKRQYAQAGLAFQEMPQEYAHGVTLPGGVSFQEWDIFHFVIMHYEVNRMGSGGIIGGLGGNLAIGVPPIVHFGNERQKKQWLNGIFTGETSFCLGATEPTGGSDLANLKTTATKSKDGKSYVVNGHKKWISGGMTATHMTTAVRTGGPGAKGVSVLVIPLDSPGVSRRKIKNSGFHAGESTWVTLEDVVVPVENLIGEENNGFRYLMTNFNRERLIMAVGMNSMARACLEDAWAYALDRHTFGKPLFSHQIIRHKLATLARYIESHWAWIEQIAYHAKTTGTVGNELASRIALAKVHGGRLLELANREAQQIFGGAGYQRGGVGSRVERIGRDLRVSVVGGGSEEIITDLAIRQEMAQAEKRGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB4</accession>
    <name>A0ABR3YSB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="252" mass="26503" checksum="682D31CB65C4C043" modified="2025-10-08" version="1">MSINFDFRNKVIAVTGGASGIGRATVQLLAAAGARLSIADVQNPQLDCIISEIRASGGDATGYCVDVANPAQVNLWITETRQHFGQLDGAANIAAIIGTGINKNRVEEIEDNDWAHVLTVNLTGVMHCMRAQIQNLRDGGSIVNVTSVAGSMGIAKNAAYSAAKHGVVGLSRSAAKEVGDRGIRVNCVAPGRIETPLQLQAVSSLGENDTAPYSIKRKGEAKEVAELIAWLLSDSTKYISGTVELIDGCWVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSI5</accession>
    <name>A0ABR3YSI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007957</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="46977" checksum="17F6056FBBFB86C8" modified="2025-10-08" version="1">MTASRPLHVAIVGGGITGLVLAIGLRARGVSFTLYERASGFSEFGAGIGLSPNAEIAMTLLDPQLHAAFKEAVTPNGLDYFQWIDGFNTNDHIFKLHLGKDGFQGGRRSEILGAWAALVDQANVQFNKEVVSVEDPKDGPVTLHFADGTTSTAHVVIGADGVWSRMRTLLFGPEYRATYSRQYCFRAVVPMEGAVAALGEDRSSSRFMYNGPGAHAITYPVAKGAMLNVLVVVQDPKPWTTTDTDNQGKVSTDTGVANRQTTGRGHREDAEKVFEKWQATPRGVVSLLPETPDRWAIFDMLEHPVPAYNRGRIALAGDAAHAAGPHLGAGAGFGIEDALALSTIFAEVKDPSTVDSALSAYSKVRYERTQWLVRATRDAVDLFQWQGPDPNKGKDAATFGPEITWRFHTVWKYDLEQMQAEVKALYVAALGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTJ9</accession>
    <name>A0ABR3YTJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit BET3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007759</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="192" mass="21887" checksum="EE2B6945AE70F9F5" modified="2025-10-08" version="1">MSAAKAARVGEEIWKTRIDKVNAELVTLTYGTIVAQLCKDYDNDYIEVNKQLDKMGYNIGLRLIEDYLAKSVSMKRCNNFRETADMISKVGFKIFLNTTPTLTNWTSDGKQFSLVFDELPLADFVELPDDGRAQDELWYSNILCGVLRGALEMVQVQVEAHFISDVLRGNDTTEMRISLIRYIDDELPPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU30</accession>
    <name>A0ABR3YU30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007368</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF103">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="490" mass="52878" checksum="F246A19CF6E1AC60" modified="2025-10-08" version="1">MAPPKDLPKVSELHAYNNAVAGHAGTLSDADGDLFIKPCVQAEIDFYKEVFEGDHEDLASIMPVYMGSLMLNETTDEAAAAVAAAGGVVSAEVTQAISSLDTQSQQSSLPVVVSPPAADAPSTTTATATASTPAAGAASAEAPVEALVDNITWVPRGSASIKTDRAVVLDNATQGYKKPNILDVKLGRRLWGDTAPKEKQKRMDDVCKSTTHAKYAFRISGMRVYQGQEAAAASPDPTDDGAGYRVYDKDYGRKDINDDNVVEAFREFLFNEKAGVDEEHSRAMAEAFKAELEHVYDVLEKERTRMYSSSLLFVYEGDGPTLQAAIAEANARATARERTTVSPTPIRVVEAEASCEEPETAAAVTFLGVESAHVEVDLEQRSRSRREVLGKAADRSSSRTDSGIVIDDDDMEEADLNLTEVDFSFGDDVDIDILGGDDDSEDEEDKAPPIYGLRLIDFAHAKFVPREAGPDKDYLHGVKSLIKIFDELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU62</accession>
    <name>A0ABR3YU62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF18">
        <property type="entry name" value="ESTER HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="346" mass="38592" checksum="E30D31DC430E68E7" modified="2025-10-08" version="1">MNNSSLLVRLGLRQSGPWEPPKLLDRLLSSPIRAAAHYLYRWIVGVRGWATRRHFLDTVEAQGTPKVRVVCISDTHDKIVPEIPDGDLLIHAGDLTDHGTPEDLQRQIDWLASLPHAHKVVICGNHDSWFDPSARVAKGMDVDTKGPQFPDNMYYLQHETRTIKFANGRSLKVYGAADIPRCGPDSFSYQYDRSTPPWKGVVPSDVDILITHPPPRHHLDLGLGCYGLLAEIWRVRPPLHVFGHVHWGAGRQVVFWDETQRAYEVLTEDGKEYGQEFKTESLGNRLSYLGRLVAAATMATILLPVWLFAPDILAAEGRGSSSILVNAGQMYGNTGKLGNSVQVIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVH7</accession>
    <name>A0ABR3YVH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GOS1</name>
        <name evidence="12" type="ORF">Sste5346_007428</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of several multiprotein Golgi SNARE complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027109">
        <property type="entry name" value="Golgi_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR027109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="236" mass="26534" checksum="29D50BAEEA93F647" modified="2025-10-08" version="1">MASAGGNSGWTQLRQQVRSLESQTESSLHTYSQFSATSSIPLKPSEEEKQTEKKLEELLSKRENIIQKLTRILDSDPNLTASAVKQNNLALLREKYEEHRRDMSRLKVQLNHARDRVNLMAHVRQDINAHRAGGDGAEGGLTGEAAEAEYMLGERSRIDNSHDMVDSVLSQAYAVNENFGLQRETLTNINRRITLAASQVPGINTLIGRISSKKRRDGIIMGSFIAMCFLVFWFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM8</accession>
    <name>A0ABR3YVM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF domain-specific O-linked N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="1">2.4.1.255</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Extracellular O-linked N-acetylglucosamine transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_007365</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:90838"/>
            <dbReference type="EC" id="2.4.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48908"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:12252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:90840"/>
            <dbReference type="EC" id="2.4.1.255"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF148">
        <property type="entry name" value="EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="12">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="262"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="36975" checksum="A8B8B99772AE4487" modified="2025-10-08" version="1">MEIWSMTMTMDVLRMARKEDDDKNEPFYRAPIDMDKTHVVILDDHGPGPTMDLWRLFSKHPITTLKDMTKDAGKVPLPVRDASSFASTNLVVPLPGGSNPLWHNDWIVRDCQPSDAPLLHLFVQRVFAHFDVPLLVGPRTDTTDKDGGEPIVVTFIDRRGTRRLLNNGPLFKALRTRFPTDNVIIQSIDMATLSLPDRLKVVQDTDVLVGVHGAGLTHTMFMRRGAGAVVEIQPSGLAYKGFRNLAAMTGQPYFSAEAEMVAQGEETEEERADFDGNTKAPARSTSKKGNDPPKVWQASNVRMEEERFLALVDVAIKSVYNEGLRNKHVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWF6</accession>
    <name>A0ABR3YWF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006878</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="345"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="13"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="652" mass="71769" checksum="BF455FD06969B57F" modified="2025-10-08" version="1">MYRGLDDSSVEIAANGSSMHNNLHLSGNDPERALPPPGSDTGGNQPMPDLSTPNAVVTTASTLVGLAEPRLEMQSEVPSDREDAEKPRAWDFQLPKLPEVEAIDILLAVAQPFGTMEGDEAKFNLRELCAAMQQGADLLTIKRYLQSFPDAVVRHRINGTVEGIPSIFYVIKTNDPALLRLWASYGADTSAIHQDTGTPLLAYAIVLSELLGGRNTSPIVATLLSLGASPASIPDVFYKSYNRDLSEDALLRDVDGLDKSPKKEWQWCQAPSVRSNLARTIHLTQRYYLDRAAKLPRAGTRHRQIATLRNAEAILGIPYYLIGQTVAANHLLRKMMTFITVPSKKPLVLAFAGPSGHGKTELARKLGDLLGLSLQVVDCTIFNDERELFGPRAPYVGSERGSPLNNFVAQHAGQRCIVFLDEFEKTSKAIHQSLLLPFDNGEYQDRRSLATVDCSRTIWILATNALDETILQFCDANPAILQHDAGNGVEIDHAMSQRLVKTLSMNLRTEFLGRFGAPVTGRVSDFIPFLPFSKGEQGVVVHKFLLELAERVAAPVRLQLGTEEQLLGNVRLRVRLDASVCMRLAKAEYSEELGARSLRKAVEDVQDRLVESYLDDEREIEEGELVQPTAFVVDVRADEVVVHKCDGSKEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX36</accession>
    <name>A0ABR3YX36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932973" evidence="1">
        <location>
            <begin position="20"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="68" mass="7621" checksum="870C59508AE8F1CD" modified="2025-10-08" version="1">MRFSFIVSAFLAGMKRSTGLTPSVKTDKVAGDNKEMNKWIDKYLGVGEWVMDQSVALAGSSSWFERTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX55</accession>
    <name>A0ABR3YX55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy-related protein 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="327"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="673"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="758" mass="83299" checksum="FC712E3B5E09A0D7" modified="2025-10-08" version="1">MANSSFLSRLSLSRDEPPVLPLHTKSLRHKPSEYDLEELSPRPSQSVLFSATDNEPPDFFPESPPTKSGLSSVAFAYQDVYRDQPSSVRLSSRRPRDYNYDDDRSTSQTKEPVLFNGPPPPIATSVLLRRDVQDRSGSVLEHGRRRGDHYMGGSTVTGFSSIRLPTNTVILEPAGNRQRRRDGTNFDGDSTWTILQRRERALQNDIQKYLDVQSTGLSAGLGRGPLNPSPSPGPSSDGDRGGGSRGSRSNTPTAESLAGRSLRLPTDRATPTGAVIPVRQPKPRKMGLRTARLGIARSISLLADLKAEEDETLSSALQARKRALAHLRRLAGRRNDIARELETLETDDTEPLTRELKTMQSAHDITSKQITELEDQLAMLRQRKRTLESRIEDAMSQRESGLSGYRGALKDVESQLTAVLRRPPIQPLDVDALGLQGGGGDHPKEGGIRLEERENDEDADASAGMEFLRLLPERRTAEMARFWWENEIRLLGRRKAEVDTERAALEEGGAVWQEAVQLVSDFEANLRKEMAGGSDDGTDTKKGKTRTPTPEERMRTQLQTMATVIKGLRGHVQTAENKGWNLLICAIGAELEAFQEARNMLRQSLREAGIKIEDDDEGEGDVGNTMDGTTDSRNSNGDDFLIDTRGLDTTKSATPTGFGLDDHEDSSATPRLARSTSDASAVAAAAAAAKKSRDRDDQTASESDDNDVPPGLLVTGEDNLDRVSTNGSQNQHNDKDDSSENEIPPEFLSEHQADDDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXQ6</accession>
    <name>A0ABR3YXQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucuronyl hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="55273" checksum="8550955DFDD8800E" modified="2025-10-08" version="1">MPSSPSSTSSEGAVHSDNTSVDGTLDIMDSLDTKMASSGATSKPLQAPLLQRFGGIFAENAVAKITRTAVEALVDNDPPTRYPEYVPQTGEDANQYALREADFWTCGFFPGCIYLLLERFNKFPHTIALSSKTRALAKATLEKTAQSWDGPIRYMAGRTDTHDMAFIVMLSQRSCYEQYHDAQAREAVIKAAYALHSRYNATVGAIRSWDMLNQNGVLVDSLTEDFLVIIDSMINLDLLYYVAGLTGDETLAAAATSHADAVMGSVLRDESKKGDSTPLYSTFHVANFSPVTGAIKELRTAQGYARDSTWARGQAWGILGFARTFLRTGEPRFARAAAGLANYFLLRMDTSPDCVEVPGCNGPKRGRYVPLWDFDAPIDPNTVADTGPLRDSSAGVIAANGLLVLSQALRAGGQTAEADRYLQAAFDIVEDTLALSLARETAEFVDEETEVAKVKDSQAGQTFAAILKHATANANARDHHRYWNHGLVYADYYLLEFGNHLLRMGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ7</accession>
    <name>A0ABR3YYQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="16636" checksum="C695F7660844EE7B" modified="2025-10-08" version="1">MSKSNFLDDLTTGLKGIRGAGDALRGELMEAVDHAFDSNSSHPTTADDINRNHAISEKGKADMAAADNMVARHEQQHREKKAAKTGMASTGAAETGAASAAFSNQGAQTGAAPVATHESTADAYAGGAAAPATTANTAAAAGGQVPVGQPQTGVPVTGTEGTASHPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZL2</accession>
    <name>A0ABR3YZL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">6-phosphogluconate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015814">
        <property type="entry name" value="Pgluconate_DH_NAD-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF2">
        <property type="entry name" value="CYTOKINE-LIKE NUCLEAR FACTOR N-PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09130">
        <property type="entry name" value="DUF1932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="3">
        <location>
            <begin position="10"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphogluconate dehydrogenase NAD-binding putative C-terminal" evidence="4">
        <location>
            <begin position="242"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="37102" checksum="019211C7E2362440" modified="2025-10-08" version="1">MTMASQSLAKVGILSIGDMGMGIAKLLIANGFSVATNVTGRSQDTIDRAKAANVDALPSDAALAAHCDIIFSVVPPRDAIETAQRIVDALPEANRPADKPLYFADMNAVAPSTCKTIAALFAAAGTQPPVHLVDGCILGGPPQLRPAAATPPVVTPSSEADKDGKNASGGTISSDASAPLEWYRPLMPTSGPHNLDAFPTLATALNSRHIADKVGSASGLKMCFAAMSKGYSAIAIQAFTTAHKLGVLEDLQWAMGSLVPGRVKQTEGALTGMAPKAYRWVREMEEISDTFSQEAGFAPDLFRGAAGVFKAVAEDTVLGQEKVGQRKRGRTAEDVASAMAEGLEAKQQKKQKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A6</accession>
    <name>A0ABR3Z0A6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_006233</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF5">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168817" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="26"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="254" mass="27231" checksum="61E2190D32ED43E7" modified="2025-10-08" version="1">MIFSTHLVATLPLFAGIVHAATSTAGHADFTWPTPRPWSNANDQSIPCGSASGAGDRTKFPLANGAVALQINDESFKVNMAISYNSDPSVNGDFVNIVDYSHFPVLDPGNECYAVPDPLSSVLSGQTATLQLSYAAYENGRYRTFYSCADIVFVQLSEFTETVSCYNYSVETGVKTSNPGVAPTPAATSSKKKLSGGDIAGIVIGVVAFFVIIALAFLCRTSRNVRRAARITENHLRLQALRRDPSTAGFKQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K1</accession>
    <name>A0ABR3Z1K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="514" mass="55024" checksum="C53D6D1E8828B164" modified="2025-10-08" version="1">MAKDETAVEITYKSKELQPPLWVAGSFSNPPWTPQEMKHRTTPDGEHVFTKAIHVKPGTAVQYKFRVGSGDWWVLDESLPTVTDDMGNRNNVLKVKDHDSVATTHAQKPPTPPPDSPTLLTTAAGLPHLQIPGGPPRSDASTPSFVKTTMEVADTAARIDARTPESEAAEHEVPDSSIDYLDVDIGPEFPHERPGEEDDGLDAAPVFAYEYAGSYELPPGMSAAEDDHSPTSPSFPAQGQDQDFDPKDPTLERFPSNREDILSRVRTLETGLDEDTTTFEGFPASPIVSPGRKTSVGSIDAAGDFFSISPTNTSNRPVGSRRTEPHKRNTSRDSLVFDPPPSPSPSLQCIVEETGTDDKLGALLPEPVESDLLSPAAAPKSVSPNSEAVSHNSEAVSPKTTTAQLASPAIVVHEAEESADSPKPVNGDNAEEHPGAFPDSDDEGPSSTVAGSQGENRETAAAANQPRSGTQASHHSTGVEAKGNSNWFSAFIRLVFVDWLGGFLGSIFRSRRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1U6</accession>
    <name>A0ABR3Z1U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="318" mass="31750" checksum="992F9CAB4ABC2B76" modified="2025-10-08" version="1">MADFNAPPGPPPPKVPEGWVARWNDQYKEWFFVNTVTKKSQWDKPTAPATGGGDEPDGPPPSYSAGSGPAPSDTKKNPFRSDNDSDRRDGHSTSGQEAEDERLARQLQREENERATSSHSGGGGAASSYMSGGGASPNLSTSGPGSASGDAPSGQRGLLGKLFNKTKTSSSNNYGSNNSGQGYPGQGYGPSGYANTPPPPQQYGGGGYGGGPGYGQPQGGYYGGGPPPPQGYYGGPPQGYYGGPPQGYYGGGYPQQQQQPQRQGMGTAGAAALGIGGGLLGGVLLGEALDGGDDGGDGGGDGGGDWGGDGGGDGGGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2T5</accession>
    <name>A0ABR3Z2T5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit J</fullName>
            <shortName evidence="4">eIF3j</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 30 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF-3 30 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">HCR1</name>
        <name evidence="6" type="ORF">Sste5346_005627</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit J family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03009">
        <property type="entry name" value="eIF3j"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="298" mass="31813" checksum="2B1A765E38F105FD" modified="2025-10-08" version="1">MPGKWDDEEDSSSSGSGSEASTAPAPPPTLLRRANKFEDEEDEDSDVLDSWDADDSEVEREKAKKEAEAKAKAKAAAAAAAANKKSKNQRIADHVADRARAQALADADSALREGETEAERRERMRRSEQEADLQHAADLFGEASFGDAGLSAGTGSGVRKSAAALKASAVSVDASDPSKIVDLGSLPLLNPVTKLQFDKLGQTLGPIISAHSQKGPYVLFAQDFIRELCRGLPSDQIKKINSSLTSLANERLREEKASDKGGKKTKAAKTKTTLAISRPSTIDTGNYDDDAYGDDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3L9</accession>
    <name>A0ABR3Z3L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005355</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="199" mass="22332" checksum="F1A43607FD71E9E0" modified="2025-10-08" version="1">MPKLGMLLDPYFLYSYLSQLEVGNARFARREDLIWYLSFIMLFVLFLDWLISLGSIWHLQALILALAYTCTQDQRGIKANFFFVDIPAQLVPYSMMLVSLIMHGPGMLYLQLCGLFAAHMYDFLTRLWPEFGGGRNLLPTPAFMSRLVPSPGRVEDHGFGRAFRPPRANDTGSSTGASTGGVLPDSWKTRGKGNRLGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3W3</accession>
    <name>A0ABR3Z3W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="434" mass="47564" checksum="372092E4B5B2F9AB" modified="2025-10-08" version="1">MSHTEPMEIDPQASACTMASASTALVLFSLDKTDKTSMHAGQDGRTKEPNSAATAIALPDSGALDSSSDSSSTATLSSPTLPPIKPRAYYCVTRLPRGEIEHRAAMGRCTYCDDENHSRTTCASGRLMRRVPKRVLNERLGRSVCPFCGDPDHDKHCKATCPLRIMLQEVLDAKEEAYRNSTLKPTEARTQRTAADALILALERQTERKFSSYAPGPRFNNRPSRTQRSDWRGFSERGEQRKHGNGQDADQHMPYNQPPRKKVYLKRPPMSKTNAPWRIGLVHSVPMSVPEEDPFCVPTSTRVAEQDQVDLIDLDIAPPSPPSASSSNSLSGSDSDSNNSATSTPFTTPEKSNNVPSGTNFKRLSCDLSPPPLLNLLDTDVTEVVWNNIFIPPSNVAKGSEQNLVTTPDIIPEESGAGEDLIDWGIDDLDLECK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z432</accession>
    <name>A0ABR3Z432_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anhydro-N-acetylmuramic acid kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="ANHYDRO-N-ACETYLMURAMIC ACID KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605:SF0">
        <property type="entry name" value="ANHYDRO-N-ACETYLMURAMIC ACID KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="47814" checksum="4F40BEC48281899A" modified="2025-10-08" version="1">MADSTSATGGQPLDVKVLGMNSGTSMDGIDCALCHFHQETPESPMHFSLLKYGEVPLDARLKKRVLNIIKYDKTSASELSEVNVLLGEVFAAAAIQFCADNGVDLKKDVDAIGSHGQTIWLASMPDEGIPRSALTMAEGTFMASRTGVTTVTDFRVSDQAAGRQGAPLIAFFDALLLHHPNKLRACQNIGGIANVCFIPPSGPQDAYDFDTGPGNALIDGVVRHYTDGAQEYDKDGEMGKRGKVNQGMVDRFQQRIPYFSWNPPKTTGREVFRDTLADDLVAEGASLGMSPDDVVATVTRITAQAIVDHWRRYAPTDRPVDEVFMCGGGAYNPNITDYMKEQFPDVKMYMLDDAGIPAGAKEAVTFAWQGMEALVGRSIPVPDRVETRRPYVLGKVNPGENYRAAMRKGILFGAGRDQLGPVTSMINYVDGKVFDNKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5N6</accession>
    <name>A0ABR3Z5N6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oligomeric mucus gel-forming</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MUC6</name>
        <name evidence="3" type="ORF">Sste5346_005043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850:SF2">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774217" evidence="2">
        <location>
            <begin position="20"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="535" mass="52361" checksum="2BB548C0E5F59C61" modified="2025-10-08" version="1">MFSTTNVLLALAAARAAIATGVSVTPHDSYSSSVGVLGCYIDTNRVAYWPGSVDCNNLCVKVTNGDRSVNLLRIDQSGGAYDISYDAWNYLQTGSSATVDPISGGGVAMEYEEVDASECASLIKTAGNKLPLSASNSMDFVASCLADSSSWVAQNHVLYNIADPLCSLGYDETCTLDLSVSNQPSCPHTLGLTTSLTSTHVYNIEYPSGKCVDASSGDEVSASVALAGDSADGSSASSGSSISGSASVAAAPEAAAAPASSSAAAPVVAITSSPAAVEAPTTSSSSSTAATQANSPGVFVATSQSAGNSQQVSSTSSQSAFSSVLSSSSSLSSSLSSPSTSSTTTATIYKTATSTSTVQCSTSSSSSSSTPSSSAPSSSVPVPVVTVPTSSSSPSSSETPCLTTSQTTTSISSAAPAPTTSTSSSAAAFSSSSSSAATVSSSSSSTKKSSSSTVKPTTSTKTSATTFAKSTLVVAPSSSIAVVGTGSIRPSTSATGSSGASSPSTVVVSGASAGVASSLRIVVGLTGAWAAWMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z686</accession>
    <name>A0ABR3Z686_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004878</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="63572" checksum="49ED8527C06E0A7D" modified="2025-10-08" version="1">MKSPESLDMPRLTAQFTALATSLSQNATKPVKYALALAVVLVGLYLYLVPNSITDPRRRKLPPGPRHWPFIGNFYDLADGEQVRIKVREWHRKYGDVFYTKIGATDYIWLSSPKAVKDLMDRKSGIYSSRPYLPLAQDVASGNSRQLFMPYGPAWRNLRKHSHALLNIGAATKYKPVQDFESKVVLQNLLDQPDKFYTISRRYSTSVIMLVAYGIRVPTFEDPIITKIFSVMENLSIIMAPGAFLVETFPALAKLPEFLVGNWYTWGKRTFKHDSKIYLDLWENLKKTSDEGKARDCFCKDFYLGKPEKNGIDNLLAAYTCGGLIEAGSETTATTINNWILGMLLYPDELKKAQEEIDRVVGLDRLPQWDDEKALPYLRAMIKETLRWRPVNKYGMYHSSTEDDWYEGHFIPKDSVVVLNWWAIHNDPSRYPEPDDFRPSRYLGKDLSAAEYIGINDPYERDHFAYGAGRRVCPGVHVAEKSLFIVISRIVWGFNIRKKIGIDGRPVEPTTVMMPGFLSIPVPFECDITPRSPERAKLIREAYAQSQVEGLHYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7J4</accession>
    <name>A0ABR3Z7J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHA2</name>
        <name evidence="9" type="ORF">Sste5346_004920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="7">
        <location>
            <begin position="5"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="230"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="35870" checksum="8E691C49C2730147" modified="2025-10-08" version="1">MARPAVAFLGPVASYTHQAARSVFAGTDSELLPVATIKDVFETVRNGDAAYGVVPFENSTHGPVTFTLAGLADRDGAYEELSVCGETYLAVHHYLLGRKQKPSTENTEVDQSASGVPLTSLDHITRIYSHPQAFGQTTAFFRKYFPNADRRPEMIDASSTSRAAELAAADTTGASAAISSLMAAETSKLDVLARCIEDRADNTTRFYVLQKSKPKAPATTPPTTCPKSLVSFTVPHRSPGALADVLECFRRARLNLTSINSLPSLVMPFHYLFFIEFEHGHEPGSKEAEAAEASTGDSADERVERVLSEVAKVAETYRLLGTWNKPEPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7T6</accession>
    <name>A0ABR3Z7T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004724</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="41"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="307" mass="33675" checksum="ED34A3050CDF88F0" modified="2025-10-08" version="1">MPSVTEQDTATATAPLPVYFIGHAGASLLFREDPNSVVVRRNLREIGRKIQAITPPPRAILTLSGHFEASEIHGPGVIEVNVKPETPILHDFVNDFHDTRPELYKADWRHRDDPALGTAVWKHLRGLASNPIAAKRVERGVDHGLWVPFTVMFPDEAPLEIPVVQVSTFHGYDLASQVRLGEALAALRRQGFLIIGSGMAVHSFSSLAEIAAETTDEGRAATTAKVLQESRTLDDQIRAATLLQNGDERRAALLALEPLYEFKRSHPTVEHFTPLLVAAGASGDADVEVLGEDVVEPGFSYINFRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7V4</accession>
    <name>A0ABR3Z7V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-galactosidase</fullName>
            <ecNumber evidence="4">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_005078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048912">
        <property type="entry name" value="BetaGal1-like_ABD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048913">
        <property type="entry name" value="BetaGal_gal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21317">
        <property type="entry name" value="BetaGal_ABD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21467">
        <property type="entry name" value="BetaGal_gal-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006336">
        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046695929" description="Beta-galactosidase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 35 catalytic" evidence="8">
        <location>
            <begin position="42"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase 1-like first all-beta" evidence="9">
        <location>
            <begin position="415"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase galactose-binding" evidence="10">
        <location>
            <begin position="556"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="665" mass="72382" checksum="4D6404E78DAC6A12" modified="2025-10-08" version="1">MLLSTISIALWTTCLWAASSASPASTPTTSAATPAFTYNANSFLLHGAPYIIIGGQMDPQRVPPEYWPDRLAKVRAMGLNTIFSYVYWNLMEPQLGTWAGGSGSGSNDIARFMMLAQEAGLHVVLRPGPYICGEREWGGFPAWLSQVTDLKTVRSHDPSFLEKATSYLTRLAADLKDTQVTKGGPLLMVQVENEYGSYGKDHVYTSALRDVLRANYDIPLYTNDGGVDWTLAGGSVPGVLAVVDGDPRGGFNARRLYIKDASMLGPLLDGEYYTLAPDFWGTTQPHNVPNTQQTAAFARDLEYVLRANNSISLYMVHGGTNFGWGNGALWRNNNVSAPFTTSYDYGAPIDESGRTTTLYTQLRKTILGLLPEKERAAVPTPPPNVPHMALPAVTLTPYASLFDTTPTNSSSIASPLTMEALGQAYGLILYEHIYNGTSPLQGVLLPGDRPRDRVLVYVNSRRVGVIDSTYERPATVTVTLKAGDRLQLLVENLGRVDYYSQEATTANMLLDPYKGVRGEVTVGGTTLHGWTSKSHPLEVPPTSEPLKNTTVGNLGPTFYRGTFSVDTPPSTETAYLDTFLSVPAGTKGAVWVNGFHLGRYWVVGPQQSLYLPGTILKVGVNQTNEVVVLELEPENVVAKKIPFTVVGLADRVWANHPDPDAPLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P1</accession>
    <name>A0ABR3Z8P1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Deoxycytidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">REV1</name>
        <name evidence="9" type="ORF">Sste5346_004652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17719">
        <property type="entry name" value="BRCT_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01701">
        <property type="entry name" value="PolY_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1630">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1280">
        <property type="entry name" value="DNA repair protein Rev1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053848">
        <property type="entry name" value="IMS_HHH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031991">
        <property type="entry name" value="Rev1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038401">
        <property type="entry name" value="Rev1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21999">
        <property type="entry name" value="IMS_HHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16727">
        <property type="entry name" value="REV1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="62"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="UmuC" evidence="8">
        <location>
            <begin position="413"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="817"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="901"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="978"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1034"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1123"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="851"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="908"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="981"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1132"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1173"/>
            <end position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1292" mass="143155" checksum="9ECC3A57E84C455C" modified="2025-10-08" version="1">MTNRQLDKNSAAVRKQLETRKFEGEDGEEYDASRFGEFGDYFRRKKLKLLNEDTIMRQSVQGKPQIFKDVTAHVASYTQPPAEELRRLLVLHGAAYIKYLDYKTMVTHIIASTLPPKKADEWRRLRVVRPAWVVDSIAAGRMLPWHDYRLINEGPGQKRIQFDAGGKMAVKEGRPDQMAGYREQSKDSYYADQMKQFAAAQERAGSMTSSIFRQLETTVMGDDDEHDFPNFGIDSNTLSSLEKGKGKEEGVEVHSSFNPNYLFEDIDIDDTYLKEPDRKPEPEPEPYQDLPPGQGMLQNNIDDIYEEEMAELQASSPSKLPKDTSREALRDDTPRKPITSEEHNAMLLADPKIRKASTANPDFLKQFYSESRLHHLSTWKAELKSKMQRLAAEKGRHVAAPKTSKNSKKRRYVMHVDFDSFFCAVSLNSAPEYIDKPAAVAHSAGNASEIASCNYPARKFGVKNGMWMRRAMELCPDLKVLPYDFPAYEEASALFYEAILDVGEGSVVQSVSVDEALVDITSIVVAKGQGENNDLTILSREQDVANTLASNLRQQIKAKTGCDVSVGIGGNILLAKVALRRAKPAGQFQMRPEDVLDILGELKVDQLPGVAYSIGGKLDEIGVKLVSDLRALSKDRLVTVLGPKTGERLYEYARGIDYAAVGDQPVRKSVSAEVNWGIRFVSQDEAEEFVSNLCKELERRLLNEQVKGRSLTMKIMKRAADAPLDPEKHLGHGKCDVFNKSVIFGVATHDAEQIAKEAVSILRSFHFSPGDLRGLGVQLQKLEPIRGGGGLDSAVHDSSQTKLSFGNAAVSTGALRPAPKLPVLQQTADKPKQPRKSIFTTPIAPPISRRPKVEEPKREEREISPPSMAFASTQFFMPANPDPSVLAELPPDIIRRLVGQQPGEAESRTGSGSNTNSSNSRNLSPIKRESRGPSPAVAAPTKSTSLLGFEDLPPDIDPEVFEALPPDMRAEVLAEYRRNTPRQQSDSPASSPHRGNKTKAVNLSSGSGSNNHNKKGSPVKRGIWGTRGLAAAAAARERRHDAQANRVQTSIFVPLPPPGDTGSNSNGDDGLEELDPEVLAALPDDMREEVLEDYRRRKQARLDQQAQQLYAQQALRFEMPASRGRTGAPAAQQGNGESSSTVRERRPLPPFIPFKRPMLQFPPRPPKMSFRASSSDPSSSSSDQETPVILSLADTKAMLKTWHSATRGDGPHETDVEVFERYLAGVITQECDMEKARKLVVWLEWLVEDSDVPEGYDEVDTVGLQSWQFALGRIKEAVQLAMQSRGLGPLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8X6</accession>
    <name>A0ABR3Z8X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF3">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="136"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="463" mass="52439" checksum="0A09DD2AE0459B79" modified="2025-10-08" version="1">MTRDSLSADDGGHVTKTPSNAHSHHSHKHNNHVSHSKQQNANAAAVEYGYPHGHVGYLSESEAEAFAEFKQYITEQGDYKPKTETTPASHDDPTLLRFLRARRWIVPDAYKQFKETEDWRANNHLDVLYDTIDLDAYEQSRRLYPQWTGRRDKRGIPLYLFEIRHLDSKAISAYEKTANNTYSKAASDGKTPAKLLRLFALYENLTRFAQPLCTEMPDRDYAVTTPITLSTNIVDVSGVSLRQFWNLKGHMQAASTLATAHYPETLDRIFIIGAPMFFSTVWGWIKRWFDPVTVSKIFILGHHEVLPTLLSFIDIKNIPKQYGGELEFNWGEMPNLDPAIRERATWEQGFDSFPKGPLYWRPLPTADNGEERVECIAVGSENQVDRLVRVCTLPKHYKGEPEKTDEEEEEDNFEEAAEEQPKEAAAENGAAAAAVPDIQNLSISEKTKDAKAETTAVEPEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9A5</accession>
    <name>A0ABR3Z9A5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="30"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="546"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="61251" checksum="13B780EE8D693BCB" modified="2025-10-08" version="1">MSAHRAVQARAENALVDQTNLLTKSKLLAVFAALSVALLTSLLDQNGVSTALPAIATALDAQDSISWAGTSSLIANTTFQMLYGRLSDIFGRKGVFLAAIALLAIADTACSRAQSAAVFYVFRGVAGVATGGITNVAMIIVSDVVTLEQRGTYQGILGAMVGVGNVLGPFLAAAFVESPHTTWRAFFYLLAPVAAVVFVSSYFLVPPSNTVTTKSSFVAGAKNIDAFGTLASSAAVIFLLIPISGGGAYYAWSSPMVISMLVLGSLLIVAFVVIELKVARLPMMPISLFHNPVIVVMLVQNFLFGAVYQSSLYYVPLYLQNAHQYPAVVSAAVTASLVAMQTLFSILSGLYISWQKRYIEVLWFGFGVWTLGAGLTLLYGRRTSPGFLIVPLLLSGTGIGCIFQPTLVALQAHAPKPLRAVIISNRNFFRSAGGACGLAISAALLQAVLRSHLPDEYRYLASQTYALPSNLPHADSSAILDAYMAGSRAVFILQVPLLGLCLLGTFLIRDRGLSPPEEKVAVNEGDAAATEVVLVVDCEEVIDSANERATAGDKEKEKAIDTDKEASSSEDVLPIPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC37</accession>
    <name>A0ABR3ZC37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteinase inhibitor, propeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF1">
        <property type="entry name" value="INHIBITOR I9 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247712" description="Proteinase inhibitor, propeptide" evidence="2">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="9953" checksum="0AE0F71D2EB5DF0F" modified="2025-10-08" version="1">MKPASLFAIVSALAAGAAAVDLKKQVVITYESNTPDWVLTEAKDAIVNAGGVITHEYNLIKGFAATAGAKVLESVQTMGSKYQALIEEDKVVSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC52</accession>
    <name>A0ABR3ZC52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003906</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF14">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="538"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="113"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="619" mass="68513" checksum="6FADC32D45663025" modified="2025-10-08" version="1">MSAEKTGEKTALPGVNIEHAVGETPVVTPALGANAEDPDDINPLRGIPREELLADVERFARETGLEGHLDLLQKGALLVQSPYNEVDLTEDEARAIREETTHKWKNPRALYFTVFVTSIASAVQGWDVTGSNGANLSFPDAFDIADTGAKCEAAGNCSNNSWLIGLINAMPFITLSLFACWLSDPLNHYFGRRGTIFIGAIFSLLAPIGSGLSQNWKQLLACRMLLGMGMGIKDVTVPVYSAENAPASIRGALVTTFQMFIAFGIFLGNSANLAVRNTGNISWRLQLGSACIPALPLLMGVLFCPESPRWYMKKKRPEAAFKSLLKLRNNPIQAARDLYYMHAMLEYERDHIGQTHGPGVIGFAQRFGELFTIPRNRRATLASFIVMIAQQLCGINIIAFYSSSIFTNAGASVQKALLASWGYGLVNFAFAWPAIWTIDRFGRRFLLLFTFPHMAWTLLAAGFCFWIPSTSPASLPCIALFVFLFAAVYSPGEGPVPWTYSAECFPLSHREVGMSWAIATNFFWASVLTLTFPPMLQALGSVGAFGFYAGTNVIALILIFFFVPETKQLTLEELDNVFAVPTRTFAKHKLTKVLPWFIKRWVFWQRDAVCEPMPRHREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCH9</accession>
    <name>A0ABR3ZCH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF124">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="276" mass="29469" checksum="592DC6056E822E50" modified="2025-10-08" version="1">MSTDNQVRRKLEGRVAMVTGSSSGMGRAIALGLAAEGAYVVCSDLKQEPSPNGFEADKHIPTHEVISQNGGRSTFKKCDMGKTEDIVNLVSFAVTTYGKLNIVVNNAGLWLPLRDFAEETDEMWDAMMGINGKGTATSMRLAIRQFLKQDIDESGSRGRIVNISSSAGITAVRREATYAASKAAVSMLTRNVALDHAKDSINVNAVCPGVVRTAMASTNFKDPAIIAEMKKGTPWPRLGEPSDIAKVVVFLCTDDAQWVTGQNIAVDGGFTAGIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCZ3</accession>
    <name>A0ABR3ZCZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sorting nexin, cytoplasm-to-vacuole targeting pathway/endosomal sorting</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATG20</name>
        <name evidence="11" type="ORF">Sste5346_003996</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06867">
        <property type="entry name" value="PX_SNX41_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044106">
        <property type="entry name" value="PX_Snx41/Atg20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051079">
        <property type="entry name" value="Sorting_Nexin_Autophagy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979:SF2">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="10">
        <location>
            <begin position="94"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="429"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="614" mass="68858" checksum="04A92C58A6266603" modified="2025-10-08" version="1">MWNDEDNNPYGSSFERRDSYGSSETPSSPDSRPNFDASSITSEEAQDVPDYVKPSSDADTDEDEEEDAAAVSHSELQPRRKPGGYDSRIEQLLYENPETPIYITDAGKSVENSGRYIVYTIRTGDLEVRRRYSEFATLRDALTRLHPTLIIPPIPEKHTMADYAANPTNAKQDQQIIDLRKRMLAVFLNRCRRMEQIRTDGVWWRFLDPNASWNEVLHSHPIASIPKSILKAPPLNTANPTPAHSYLPVPATSSKLKLSSGTPNIPVIDGSVARFPPESSQLSEQELDPYFTSFEASIKELEQLLMGPMEKVNRRTLSHLSSLASDQSELGARYNAFALSETAPTLGAAIERIGQAVDSSYIATEELSSSLGASFAEPMRENAQFAGVVRSVLRYRILKRVQQEMTNDDLNKKRALLDQLERSEAEARRIDQYLSGSQQIQPPRRSTSSRDPPGQHRRDGSQEDTASIDSDFPPTHGDYSSVPSAKNGPPERSVSNPGHKKAASGNSITNKIFGPIRHAVQGVVDVDPERTRRDTITKTRESIVQLEQAQVASAQDVKDASANVLRDLKRFQKEKEDDLKRYMIAYAKSQIEWAKKNRETWEEARQEVDKIEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD84</accession>
    <name>A0ABR3ZD84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004207</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="49909" checksum="3BBB98EBB92658F8" modified="2025-10-08" version="1">MSGVGHKKMFELHQKYGDIVRISPNQLSFGYPEAWNDIMGHRKRGQDENGKDPDFWHGDDSLTLVGSNRERHGRLRKILSHGFSAQAMIEQQPIFQQYASMLITKLRAAASSGKAVEITRWYNWATFDMAGDLIFGEPFGCLEKMQYHPWVKLIFMHIKGISIATALIRFPFSNTIINLMTPKSVAKDIHAHIEFTKAQVGKRMAYDNPRPDFMESMIKAHGRGEVTMKEVLANAHNLIVGGSETTATTLAGTTYLLAVNKHIQVKLYEELRANFDSDDQIDIINVQKLDYMFAVIHEALRVYPAVPSAIPRRTPAEGSYIGGQFIPGNTILGVWQWPMFHNPKFFKDPESFIPERWLGDPRFDSDQKVALQPFAVGPRNCIGKNLAYAEMRLILAKMIWNFEMELHPRSEGWLEKNVVYLLWEKPDLYVRLTPRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEH0</accession>
    <name>A0ABR3ZEH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003358</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G12570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="90"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="699" mass="76713" checksum="2436F49C6C86543C" modified="2025-10-08" version="1">MEVDSVVDVPALQQRLPSARTRDVALRISQVVSACTFCKSRKIKCDGVSPACGCCTKFGRAATCSLADGSARPAHDYVVYLQTRIQQAKARLAEGQTGHGGRSEEAPPTRAATKPSQAPTTQQTPFDFNDSSADLPSSRRRQPARPSSHAVPSTASTAIDTLIADIGALPISTSSHAHAHSVSTARRGPTLSTVLLAAASKLPLLSIVQDQEGQQFSSGANAGTGSTSTASVAACLPEESAARKLIQHYIQQVYPRLPFFSLQGFWAQFQQVYGGAGQTSDGPSSTTVGLGLNSGYSYFTVLLVLAIATSSLSRSADSMISNQARRLFQAGLQFRESAILPNTIVGVQSLLFLIQFATLNPSVLDSWYLIGVGMRNCVDLGLHQDPDPSQAMTPSLLETRRRLWWSMYSFDRSLSIGCGRPTEIADALIHVQLPSFRIESTATDVEVEGYVQRYRALQLQSEIYDALSQPPMGDEAAAAAVVAGLHRKLDAWQLSNRPERNRETLADSEWLVGKMLLFRPCRLLPERSVDELRELWVSARGFTALYRQLVETNGIFYVQVACEKVYWTGLILLYSYWKLTSSERSKVRNDRNDRNDDVQALQLWKATKDIAYILQTLSERWEDGKILAVQFDTASAKVIELLDNVDRRENMEQRLPPEVVTLSRYASLVSIWASGAEHWHGGLGAAHSEELQDLVAKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEK1</accession>
    <name>A0ABR3ZEK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_003388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF39">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="121"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="777" mass="83036" checksum="9E5C6CAC9EE23A29" modified="2025-10-08" version="1">MAPSTEAAAPAKNNKRRAPMSCDRCKSRKTKCVDPVPGPCQFCASISAVCHLDPSRRRQRPYYHVSEEEFRYMTKALEHFLPNIDLNLQSLREVVQSLEAGQPIPGAVDQQQFKYNITQPHPALPLTAPPSEGSASSGDSIVVGDDSRTTPASTATAPITTKLEDPLLAEASSIEEIDELHGELGWLRVDSRGTYRHVGADSGYGFHAAVRSLRHRRGSDVPGTGTGGNKTDIVPPFTVAPPLPPSTPDSGGGGGVPSPHALPIYNHAVSALPLVPGTAAAGSLGKGQRMQIFLPRRDLCNRCVSRFFRDIQSVYWFWSAERFYAVLDRLYAGDPSSATPAMLCSLYSILALTCESEAQQAQVTPAGAAAASGGPPPAARYLALAKGLVPALCDEADTDSVRALCLLGLALQSSMFNNTAYIYIGAAARIALTLGLHLQRAIEPKGCLQRQIDLRLYSTLFLIDLDVALCYGNPPAISDEHASAGGNSSGRPPHDLSEQILSPGSHMPLDYLTVSCELAQIRRRLSKLLYIRQGVSASSSAPGPVHFSTAVGTPPAASPSQLLLSSSASTTSSNSSPPKPSIAAVSDVLATLRAWYTAIPPHLRDVSRAASFHQRSVAVLHLRYWSATIFATRPFLLYSALHSESLAALPPAKRASFEAFGATCLDAAQQSLAVIGVMQDAGLLSSLITLDTGCILEILQVFLLGLARGGQGQADNVRACLRTLQGMEQIFWTGHAVLEVMAQLDENGLLNGDQHFSPQSETPGHFFLDIHQQQHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL4</accession>
    <name>A0ABR3ZEL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="13">Aconitase</shortName>
            <ecNumber evidence="13">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ACO1</name>
        <name evidence="16" type="ORF">Sste5346_003047</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01584">
        <property type="entry name" value="AcnA_Mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="14">
        <location>
            <begin position="74"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="15">
        <location>
            <begin position="591"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="789" mass="85332" checksum="1BF503B8ABB07067" modified="2025-10-08" version="1">MLASRQLLGKAVRSHAAFAGFAMRRTMATVSDSPLDQKVPQNIWESNNFINYKKMAENLDIVRARLNRPLTYAEKILYSHLDDPHGQDIERGVSYLKLRPDRVACQDATAQMAIMQFMSAGMPSVANPATVHCDHLIEAQVGGPKDLARAIGINKEVYDFLASACAKYNIGFWKPGSGIIHQIILENYAFPGGLLIGTDSHTPNAGGLGMCTIGVGGADAVDVMAGLPWELKAPKVIGVKLTGKMSGWTSAKDIILKVAGILTVKGGTGAIVEYFGPGTDTFSCTGMATICNMGAEIGATTSLFPYNDRMYDYLAVTKRKNIGDFARVYGNGLKADEGAEYDQLIEIDLNTLEPHINGPFTPDLATPISKFSEAVKANNWPEEVKVGLIGSCTNSSYEDMTRAAHIARDAMDHGIKAKAIFTVTPGSEQIRATIARDGQLETFEEFGGMVLANACGPCIGQWDRTDVAKGTPNSIVSSYNRNFTGRNDGNPATHAFVTSPDLVVALTIAGSLHFNPLTDKLKDKDGNEFMLTPPEETNGLPLLGYDPGEDTYQAPPADRSQVQVQVSPTSERLQVLSPFAPWSGKDATDLPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGATNAENGEANKVRNQLTGEYGGVPDVARDYKAKGVQWVVIGDWNYGEGSSREHAALEPRHLGGLAIITRSFARIHETNLKKQGMLPLTFVDPADYDKINPSDRVDVLSTELAVGKPLTMRVHPKDGAAFDIPLAHTFNASQIDWFKNGSALNTMAKNAAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEM0</accession>
    <name>A0ABR3ZEM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="278" mass="30171" checksum="AA5A4AC9A9F27CC0" modified="2025-10-08" version="1">MLPPELRLKIWHYNMPEPRIVSVRCGARSPSSSLPSLPLRRHCLSSEDAFTACSPACSSHSSSSSSPSPTLSPSPSPSPPPPSSYSPPGWCTSTATLPVNLSVCHESRTEALRRYALMFGIARQPGYVYFDPSRDILYFGPREGYMAAEAQLRTLLVLAEPEELALVQRVALSEGVLDHTGSSSSASTNLAVDVLHQLRTRLPSLRELIVVPRDETAVDSSDAVLVPLPMPPVTLPLGGPSMPCTQQQQLDPDNSEINVPNSEATKRLAKQIHTAMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEN0</accession>
    <name>A0ABR3ZEN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inheritance of peroxisomes protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for peroxisome inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024758">
        <property type="entry name" value="Inp1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12634">
        <property type="entry name" value="Inp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="611"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="611"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="637"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="683"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="725" mass="78938" checksum="0F368948DF02BE96" modified="2025-10-08" version="1">MGRGAGHDAAAPGPPRRSYTAPRLAQHTRSTSTSSHLQNQGVDAEAVKAAAAAAAMAAAAAAAEFGTSPTHSDVSSVTGSHLSTTTATAKDEAVETLYSHPAAKILSFTAGARNLDNIGSAHSRNAARSRRSLTMTAEDEIAPGTLPWRSQFDRTIAVGALSIYRAPGSVAFLSCGSALQPILPKSQCWCIDEESSKFILQIRRPQYWRIEVPVGDGGENDERARRLREVLDHILQFEKTPCPFKRTFTVELPEQPSTPLKKKPWTPVKRPETEGSGSGTGSKSQQKQRRSQSPSSLQERDEEYDDDDEGSVLSSVVSSVAPPRQKLQRSQTEQSGSERPTEFTRKEWAAMLESQKKNAAEGVDEFGRRLVPALVAEHEQRINDLKASEIEVSKMGSPWHNTGGTFSPTNGQGSGTQRDRALSLTSDISTTQKTAWPSIDGRWMEEIDQSTTTDSNSPFNSLRSWLSSAASLPSTTGSAADPSGVPPSLSSLYEDARRKFNNGIGTLEQLQQQQEMQQPRLRHRATTSSISVSNHANLPPAVNIIAPSHLRNLHSSGRATTRLEAMRRIPGSIIYRVFEILLAPPSYLLAMMLKIAARILKGEWRGSAMGKNTDTGENISAQWDYTDVDDPLGRSTELTRPDHDVGRLNRYTEADNEVYTDAEDNDDDDDENDDGDETARCFSTSPSLKRSSSSASKAGSDSDDTDTLSDTGGDPIVWTRRWALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZER6</accession>
    <name>A0ABR3ZER6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031925">
        <property type="entry name" value="TBCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16752">
        <property type="entry name" value="TBCC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="8">
        <location>
            <begin position="224"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="405" mass="43099" checksum="883A94B2FB9B2C52" modified="2025-10-08" version="1">MSQVMNPVAHNYPFAFAGKRPIMDPKERFYRQFQIEVQDIQNHISKLGSIAIVGGERKDATDSILTRISKLSLEVADAADFIPAYDQRTYSATVKSLTDQLNEELTRLAPAKPRFQFKRAPKTAAAASQAASTPAAPDNRLLRGMPDKPAAKPEEQDSTTAAEASDAVGALPVLGTAGTAVVTKNYNAEISSTSTAGGGVRKPSFSSAREVALSGHTGLHIILPLSASRATSYGSLTDLHNCVVDMSVPTSSVAHGGGGAAFQSLMLRNIERSLIVAGHVSGAVHITGLKNCVLVVAARQVRIHECDKVDVYLQCGSRPIIEDCKAMRFAPLPAVYANTDGGDSETVNQWDQVDDFKWLRSDASPNWSVLPEAERLPETVWTGAVASGPGFGTEDVLSAVGIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFF1</accession>
    <name>A0ABR3ZFF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenoprotein W family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417:SF2">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="14504" checksum="6FAE6868A35142F4" modified="2025-10-08" version="1">MLRAAYFAQELLSTFGGDLGEVALQPATGGVFTVTIETADTASSTGTGAPKLLWDRKTEGGFPETKELKRRVRDVVEPGRDLGHVDRNYGKAATAAAAADAKATPTPKAEATLAATPPTAAPTAASGADSGNTVVPVCEDCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFU9</accession>
    <name>A0ABR3ZFU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydrolipoyllysine-residue succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">KGD2</name>
        <name evidence="13" type="ORF">Sste5346_003167</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="117"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="119"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="422" mass="46194" checksum="85C8F685573323C4" modified="2025-10-08" version="1">MLSRRILHAARSAAICRPQPALRHAQLPLMFQHVRNYADLTVKVPPMAESISEGTLKQFSKQIGERVEQDEEIATIETDKIDVAVNAPEAGVLREFFANEEDTVVVGQDLVRIEVGAEGEAKAEKPAESEAPKKEEAPKEESKPADAEPKSESKPVESSKPAPAPEKKSSPAPSKQSSEPASPSPLGSREERRVKMNRMRLRIAERLKQSQNTAASLTTFNEVDMSSLVEFRKLYKDEVLKKTGVKLGFMSAFTRACVLAMKDLPAVNASIEGPNGGDTIVYRDYVDVSVAVATEKGLVTPVVRNAEGMDLVTIEKSIADLGHKARDGKLTIEDMAGGTFTISNGGVFGSLMGTPIINLPQSAVLGLHAIKERPVAVNGKIEIRPMMYLALTYDHRLLDGREAVQFLVKVKEYIEDPRRMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGA8</accession>
    <name>A0ABR3ZGA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MAS1</name>
        <name evidence="17" type="ORF">Sste5346_003483</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="15">
        <location>
            <begin position="52"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="16">
        <location>
            <begin position="205"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1898579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="52585" checksum="F01AAEC3B6F649C9" modified="2025-10-08" version="1">MASRRLALNLRQGLKAPRAGLSLPPLRRGLATPVASPALKTQSTTLKNGLTVATHYSPYASTSTVGVWIDAGSRAETEETNGTAHFLEHLAFKGTAKRSQHQLELEIENLGAHLNAYTSRENTVYFAKSLNDDVPQCVDILADILQNSKLEESAIERERDVILRESEEVEKQLEEVVFDHLHATAFQQQPLGRTILGPRKNIQEITRTELTNYIKNNYTADRMVLVGAGGIPHEQLVELAEKNFTNLPASSPQTGAYLQSKKRSDFIGSDVRIRDDTIPTANVAIAVEGVSWNDDDYFTALVTQAIVGNYDKALGNAPHQGSKLSGLVHQNNLANSFMSFSTSYSDTGLWGIYLVSDQLTRIDDLIHFALREWSRLSINVTQAEVERAKAQLKASILLSLDGTTAVAEDIGRQIITTGSRMSPGEIERVIDAITEKDVMDFANRKLWDQDIAISAVGSVEDVFDYARIRADMSRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGB4</accession>
    <name>A0ABR3ZGB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF2">
        <property type="entry name" value="MIGRATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pleckstrin homology" evidence="3">
        <location>
            <begin position="1018"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="647"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="744"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="810"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="860"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1251"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1398"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="755"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="889"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="911"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1259"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1307"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1346"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1398"/>
            <end position="1416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1454" mass="159184" checksum="80EB3AA0FAC6D804" modified="2025-10-08" version="1">MGVWETEDEMDGPLMAAAAALPTPTDTPYRTPSRTSRRSRRSVTPPRKGISPPPMPNADKTDKTDRSSKRSSKDLATDETISIFDPRRFTPTLHANLVSEILALRRDQEEKMKIIESLETALHSTKEEQESLEETALGTAKENRSLKRQLALLEGGTSSALGELAREREEAIETAGETKKRLDQTQKRLRHHEEDLQRTHDQWAKEKEEWEEEKRKFERKLHVADTRLKTVLEEVAAYHAAQVNGMNGHGMEGYELEDGTTAGKDNDAASVRTMSMTNSIRFSVVPSKPNGNSLADELNFDGDETDETDHGGRESVLSYRLHGRSHSRDSTVSRSHRRQQSNESLRRPGSVARGRFLNQSVLERLEGVTIEEDDEEQAPSPPAPKVPKVEYTDSSCQYSPPPSPKVAPQVALPEPVPIIELQQPQAPPPPIPARADRSSLHESIDSTGEIEANQRRKRVHIARPLTIEPVVMSNNLMVSVGSQTMTEEPLSPPKTPKSPPFEKEIKRASLVAPKPAPPPMVSSETQTDPPTPPASPVPDSQAGLVPLSQMLIPSISIHPPTSRPTTPREPRLPPLNKDFGCQVEIIARPTPSKSVSVQTDEIRVDKRLDRLPPHLHPSAITSRPSSPIVMISDPVAAAVDDLSKQHFVPAPGALPPRNPRRLVSRSGTPSEPPSSPPAPVPTAFGSEETHDAYPGNNDDGPLSNQKAPMRRPHRISSLFAGFDGGSSDEVDEFADADMSDSEYRTALSAPKPTAGGSSRSSNKRNSGAPSGTDSPETLPRRSSVRNSVRMLGNLAGTETYSKYTMNDVTRDSREISTGRKTSVRASRMSFEKGNGSVLGPSGNKSGVMRKAAMIQNGIATHQGLRSRSPSLPDPRDPPFPIPTRASSRKPPTSVSAPSDGQRSPTRADGWHHRRGSSRNHHRANSIRKVRSAAAIPVKPRTRRTGSRSPPLQQGPFSADEEPESPGLPPLPTNDITAPRFGSSTGSRYKHQHQASINTVITDQTNVGSVNSSNQATGVVDAIAQTMVGEWMYKYVRRRKSFGAAETAGRDDSSNDRHKRWVWLAPYERAILWSSKQPSSNSTLMGKSGRKLTIQSVLDVKDDNPPPKGCGQLFNRSILILTPQRALKFTATTPERHYLWLTSLSFLAHSQQAIPENITAPPPLPKAIPDFDLSSRSSKLRKGGIRDSIRLTKNKTATLGTMSGSSVTVPPPLPPMSVASSVVDSVPPSIPSYRPAESYVSAPSVTYTSAPSVAATSSTHQRDTSRDTAEPPVIARFHDRSSQVMVHGRKRSNTGGHVPPPLSFRGFSGPAGSSSSYYHASSNSTAANSDISQSQASSWGIPGGAGSQRTSEASSRPSGAMMNNFFDAIGTVRMEAFISPLALSQFDEYPDEQEEMRYRARRRSKEMRRRASRSRHREQRDSYNSRTTRNTDDYYAASRAGTEEDYFRDDPFKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH09</accession>
    <name>A0ABR3ZH09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPS3_1</name>
        <name evidence="10" type="ORF">Sste5346_003229</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="195"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="264" mass="28593" checksum="D454AA9178D20A8F" modified="2025-10-08" version="1">MATPGAQISKRRKFVADGVFYAELNEFFQRELAEEGYSGVEVRVTPTVTDIIIRATHTQEVLGEQGRRIRELTSLIQKRFKFPENSVSLYAAKVQNRGLSAVAQCESLRYKLLNGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRAARAKSMKFTDGFMIHSGQPAKDFIDSATRHVLLRQGVLGIKVKIMRGSDPEGKAGPQKSLPDSVTIIEPKEEQPVTQPISTDYGAKAAQQAAAAEAARAAEAAAAAPAEEEAAPAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH26</accession>
    <name>A0ABR3ZH26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="559"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="691" mass="73545" checksum="A3C6341999D13EAE" modified="2025-10-08" version="1">MPRPPRRTRAVSTRTTGVATASKESSEPALDKTTTTVTDKTAEATSDNSNDGRRRSRRSGVASEMSSATSSDAYGVSDRELKRRTSLRQTATTTSARLAEKTTAAAAPRQTRGPDASGLDMDDTFADIDTNFGDHDLGDLDDDLDAFDGLGGLDSSPAAAGSANATHTTDSTSSSFNVGLFRRGRPRQSSIHSRDDAPIRPSSRGGTATPSFGSTLNLGTFKRRAREPSILGRRRDTSRHTSRDRDAESGSEMDTAPYTSDAESSSMAARHRVGRAPRASLASRVSQVVHTAQNVADSSMSSASNTTSMMVMSRATRTRAAAKRKSEEGQREDELPKRRAVEEVAAPSLLPPNDTGVMQSVEISSSPPLSSPPRQSSALMSDADRRRYATPGGPDDEVMAPPLSSGSSSASPTVWPSLKGLANAGRRGRVNHADVVPMVPLSRQTPDLMDDDDASDISSPPSLTHSPNYRATALKAKGKAVNTRNAAPTAKTVAPLTTAALAAFLPQRHRRGRRGGNDDDGSDGDDGDNELERSALLSEDDDELAHGPRRGGLRRGRSAARTLAAVPAPAALRSASKTAAGNRESATKTSKASSGKSKRSVRRTYGSRSFSDKENQDSTTVDLDADESTFSPLPDDAFADETTTEVLPTTARKARYFGEELENAAKKFKEVDRWTLEFESVSRESSPIGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH33</accession>
    <name>A0ABR3ZH33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045202068" evidence="2">
        <location>
            <begin position="17"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="29571" checksum="7B907420BBAEE10E" modified="2025-10-08" version="1">MRPVVVLAALVASATAFPFRLLSFTAASTKTSAKDKTAVVYNFEQNKQYHNHHVHSEEKENTHQTHPTAKLTHHRLPLHGNDYSYSYRFQRSNTNPGKAVVYAPDRTHSQKKDDKKKASHATPVDKLTYKHHSRGLDNIDAAALTAPPPCQPMSPPPDEAATKARFDQFAHAFLVTKNITEAFTYISEGYINHNPAAKNGAASAWGILSPIWASQSITVLRTTFKGNFGWLNYRAGGLGEVVDRYRWDAGCIVEHWDQGEKYPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHE0</accession>
    <name>A0ABR3ZHE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002436</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="21"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="552" mass="59806" checksum="9C370116A3C7BC53" modified="2025-10-08" version="1">MFDRFSKPFLGLRGRKLNIAIAAVAGVDMLLFGFDQGVVGGVLTLESFSRQFPEICTTAACTAGLSPSAANHQSVLQGISVSSYNLGCFVGAILTICLGDRLGRKRCIFSGSLIMAVGAILQCSAFSLAQLIAGRVICGVGNGINTSTVPVWQAECSKSHRRGPTVMAELCIVVGGVALSYWLDFAFAQLEPSSAAWRVPIAFQLLFTLTVLATVMFMPESPRWLVLQQKDDQNDGDRKALEVLCAIYDCDADDAFVNAELEAVRVVARQASRGTFRDLFAMGKAKNMQRTLLAYGIQVMQQITGINLITYYAATIYENEIGLSGTLSRILAACNGTEYFLAMFPAIFLVERIGRRPLLLVGSVGMALSMAVLAISTSIASKTDNTAAGIVAATFLFVFNTFFALGWCGLPWLIPTELLPLEIRAQASALATSADWIFNFLVVMVTPIAFQSIGWRTYIVFAVLNAAIVPVVYFLYPETMGRSLEEMDLIFAKSDGWLDTVTVAKTEPRHYGRHGEVLRDMLPDVRDELGRGDGIGLGDGPNKQVTASHVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHL1</accession>
    <name>A0ABR3ZHL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_002515</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="11">
        <location>
            <begin position="16"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="10">
        <location>
            <begin position="144"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="9">
        <location>
            <begin position="258"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50408" checksum="B18FB407D50A1287" modified="2025-10-08" version="1">MSAKIPTIASNRVSDQAKKTLDIVAKFVQEECIPADAVFDAQVGVGDARWEGHPHIIEELKEKAQKLGLWNLFLPKAHYKESPGFSNLEYGLMAEWMGRSRTASEACNCAAPDTGNMEVLARYGNDAQKQQWLKPLMEGKIRSAFLMTEPQVASSDARNIEMDIRREGNEYVLNGQKWWSSGAGDPRCSIYIVMGKTDGKNKDPYRQQSVVLVPADTPGITVHRMLSVYGFDDAPHGHGHLTFNNVRVPVSNMVLGEGRGFEIIQGRLGPGRIHHAMRTIGAAERALDWMLMRINDPQKTPFGKKLREHGVIMEWVARSRIEIDASRMLVLNAAITMDEQGPKAALSQIAEAKVMVPNMALTVIDRAVQAFGGAGICQDTPLAGMWANIRTLRLADGPDEVHLAQMGRNENKRGEAVTQQIKWQQAKSAEMLKQRGLTKAEPGTRIQHRTQSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHV0</accession>
    <name>A0ABR3ZHV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="373"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="446" mass="48988" checksum="DA966814732F794F" modified="2025-10-08" version="1">MAQVLNSFFGGKADEKPIASGDADFADFAGVPDPAPDAFAAAGAAAGAGGAAAPAVTARPYTKWYNVHERYSLNDFKIEGIIFGLMAIVLIVHFVGTRLNRSKARAWAKAHAKLLAGEFALVGFGRVPSALAAQEDEGAALEALAAATTSADPSTLIKENSLFEFASYATGRQNVAFVDTKLKLIKRFNPFMVIAEYILSFFLESMPAPSDQLEATLYPFDGKEALTVAGLPAGSANKSTYDGFVWAIVNKDRMKGVRDDRFDVSITFTKDHAKLPPWLTVMSESAEITEALLTPELIKAAEVAGEALDYLIISDQPIDKPTTLDETAPRKRVFLKYRLPSNNDYESLLPIYSYFLKSADVLVQAAHLRAEVLRKVKAARESIAKEIRKADEEEKAEERALERERLRKQKRDAELSALDAKAQKKYLEREREKELRKAAKKSTMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHW8</accession>
    <name>A0ABR3ZHW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003041</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF13">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="40988" checksum="E4E8E17509D508E0" modified="2025-10-08" version="1">MEDGQYVDGSIYIYAPNKAAPIFFAVAFCISLGLHIWQCIHYKAWRLTGLYVFSNTLFTVGYVLREVGAFNYENVDIYIAQTVLVYAAPPIFELANYVVLGRILYYVPHLSPIHPGRVLTTFTAISAVVEALNANGAAYSANTTLPKKKQDTGHALLKTSLILQLVVVGLFLLLAIVYHRRTLKNNIHNKKLTNALTTLYISTGLLLTRTIYRVVEYFSVDSLHIVDGVDPNTFSPILRYEWFFYVFEASLMLVNTWLINARHPRRYLPKSTKTYLAKDGVTEITGPGYKEDRHFLMTLIDPFDLTGLLQGKDKKTAFWEQQEQQNGQVQQNGQKPHGNRTELVSNGHSASKRSNDDDLEAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIC3</accession>
    <name>A0ABR3ZIC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF166">
        <property type="entry name" value="LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="285"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="287"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="81"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="165"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="417"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="476"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="754"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="826"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="496"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="605"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="760"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="835"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="849"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="892"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="907" mass="93149" checksum="43731468B7D45CDF" modified="2025-10-08" version="1">MLATRRSDTELSHPWSFSKLETSSSALSLKSSPSSPGTRMSNTGFETPLSNAATEWSGQYSFLPPAEPIFAAQAYDHVNGSGGSGGGGSGSGGAVDSTTNSGTSTTINGVTNTGGQTQTRPSTGTNGDGSGNGSIKDDSSLNAGTSPLGLHHRRSIDPLGLRQHSVSGASQTTATPHNLGGKTPPTPTTATSEHHQHNQHHYGQHTHNGHSGVAGSDVVSMTANPLSSVLQQHQPDILSAASGAEDSSGLKEDDDDLIDDEEMGEAGEGEGVPAPAQTAAERTAQRRKMKRFRLTHQQTRFLMSEFAKQPHPDAAHRERLSRQIPGLSPRQVQVWFQNRRAKIKRLAADDRERMIKMRAVPDDFDNVQALHSPYGAVHGLGTPMASPVDYGAAAAAAAAAASSYSDHMMRPLMVDVRRNDGTNTSGGDDQGQHSQHQQHSHLQHSHHSHHLSPTGLSPGFGNIGFGSAATSGMGSSDILSPLSPGSNTDHRYGSYSSLSSGVAGATTTSGSGSGMSPRTSIPYTRQSTGSGLDGNQNQNQQGQSQQSSHQRHHIRPLQPLQLREAVSRSRSDNLQSPLRSSISWKGETLDYSNYHHGSATGGAGSTSPGRSSLYPSDGLGNGSSSAGLGGYDSYSALQAAANSNQNRTSRLRAASATLPLALDLRTTSVGAGSMGSGSPYRSVSTAAGALSPTAGTPRQQQQMGSLNGLVSSSGYATSYATSYASNNFPTSAPLTAPLDFSMSSAVSRTGAGNGVGYRAGSTSSMSNGGITDYTSMPQMSAPLAPPHDFSQAFLGGGVGTSGAASASISATSIAALSNNTSGGRASPYGTGLGHHTSSSIGSSLDRSNTGGTTASTTTTATTIGTGTAATDFSTSPTDTSSSLDGLKRKHSFTTGSNTGTNVYGSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIG7</accession>
    <name>A0ABR3ZIG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 12">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SAS3</name>
        <name evidence="15" type="ORF">Sste5346_002716</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 12"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="14">
        <location>
            <begin position="588"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="308"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="951"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="188"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="955"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="976"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1005"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1026"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1088"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1106"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1191"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1213"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1227"/>
            <end position="1239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1899850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1299" mass="141649" checksum="7F88591EB7E56679" modified="2025-10-08" version="1">MASEQLIQEELQNSAAVSEPSASSHIGDDESTGTQDRNAQLGVTDSMKSDAEAGDDEQYTGEESEEDEEDDDEEFHHEDADDYESEGAADDVDDELDEDDTVLPSTATKRHLRIKHNDGEDEEEEDDGEEDAEGEDDDSEGDHDEDEEASEDDAVGDAEGVGAVKIRPGETEEDDDDDSEASAAASESSDEEWEEQAQNADDDDDDDEEEEAEEEIGDDDEGDGESQDGAVAAHADDEEEEDDEGHNYHLDCIYCMRGYGDEPRKDDSYLWKCPTCSNEAHMECAYENRTVEELYEGNCVKKSRQEAAEAAGETMDGDGSGADQPTDGAEAANGTPPTTIHATLKVTTPRSSPALRGATANADSVPEDPADGVPRSLRKRRTSPVDSADSGMSLRKRRKNVTEDLSIDGFTDIRKAPVPSSARSLRIKPPAASQVSVVKKTRGCLILKIKVSPKDLRRITVKKRKYTKRGTAPPRISKKEKKRLELLAAQQGLSVGTDALPVMPSTTAYTQPFYSFFDKETDEQKGKPYGGILTEAEADTSKTFPTPDDRRRFDDAKQKAEEEWRARLLVMQAEAEAAQPAKKKKAAGPASQIECIEFGGWEIDTWYAAPYPEEYSRNRVLYICEFCLKYMNSDYVAWRHKLKCPAKHPPGDEIYRHESISFFEVDGRKNPVYCQNLCLLAKLFLGSKTLYYDVEPFLFYVLCEYDEFGYHFVGYFSKEKRASSQNNVSCILTLPIHQRKGYGNLLIDFSYLLTRVEEKTGSPEKPLSDMGLVSYRNYWRLVMCRYLLDAMTESKGAKLGLSIKQISDDTGMTADDVISALEGLRCLVRDPQTGLYAFRVDLTYCREYVAKWEAKKYVTLNPAALTWTPYVMGRGNATNFELGPALTAIAPREEDEEQKAAEQFVASLANGDSISTQGGLTNGVATTNDAATGADAAEDNRVDATTAMVLESTEPNDKDGVTEAKNEADIKTNGDQSTASVVASSQTVEADADHPVANIISDIKSEDEDDDEDENDEEENKGHATSAINGVATHQNHTAAPSIADTANGTQKQNGNDDGDWASAYSSIPTTRFVVFPPVSARRLNSYPRAPIGRPPGARTGIGNRARSRHSTGHVRRAVVSVSRPKKAPGSSNKKKSGGTGRGPGRWPKGTKKSDYGNAESGPGLPPAWLAKKIAAGESHKAGSGDAINGDYKDEGKPDVHEDEEAGDDEQHQPITPSRKPTATDNHDDEADAEGEDDDHAVVDTVQVHTPTLPSRLTDKRGGVNGAVLASGTRGRSSPRLGKIKGGDADTVMVDAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKL6</accession>
    <name>A0ABR3ZKL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Pyruvate carboxylase</fullName>
            <ecNumber evidence="4 13">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PYC1</name>
        <name evidence="19" type="ORF">Sste5346_002308</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>hydrogencarbonate + pyruvate + ATP = oxaloacetate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="4 13"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07937">
        <property type="entry name" value="DRE_TIM_PC_TC_5S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055268">
        <property type="entry name" value="PCB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006761">
        <property type="entry name" value="PRK09282.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009554">
        <property type="entry name" value="PRK12999.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778">
        <property type="entry name" value="PYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778:SF2">
        <property type="entry name" value="PYRUVATE CARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 13 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="17">
        <location>
            <begin position="42"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="164"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="18">
        <location>
            <begin position="580"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="15">
        <location>
            <begin position="1117"/>
            <end position="1192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1900585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1194" mass="130916" checksum="AB534FB606661034" modified="2025-10-08" version="1">MASEPLLDGANKDAFEEVFDDDAPPKEGASIQRIRANSSIMKLRKLLVANRGEIPIRIFRTAHELSLHTVAVFSYEDRLSMHRQKADEAYVIGKRGQYTPVGAYLAGDEIIKIAVEHDVQMIHPGYGFLSENAEFARNVEKAGLIFVGPSPDVIDALGDKVSARKLAIAANVPVVPGTKGAIATFEEAKSFTDEYGFPIIIKAAYGGGGRGMRVVREQSELKESFERATSEAKSAFGNGTCFVERFLDKPKHIEVQLLGDNHGNMVHLYERDCSVQRRHQKVVEIAPAKDLPSETRDAILADAVRLAKSVNYRNAGTAEFLVDQQNRYYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGATLQQLGLTQDRISTRGFAIQCRLTTEDPAKGFQPDTGKIEVYRSAGGNGVRLDGGNGFAGAVITPFYDSLLVKAICHGSTYEIARRKILRALVEFRIRGVKTNIPFLASLLTHPIFIDGNCWTTFIDDTPALFDLVGSQNRAQKLLQYLGDLAVNGSSIKGQVGEPKLKSDIIHPSLHDDAGNVIDVSKPCTKGWRQIIVEQGPKAFAKAVRDNKGCLLMDTTWRDAHQSLLATRVRTVDLLNIAKETSHALHNLYSLECWGGATFDVAMRFLYEDPWDRLRAMRKLIPNIPFQMLLRGANGVAYSSLPDNAIEHFVEHAKKNGVDIFRVFDALNDVDQLEVGIKAVHKAGGVVEGTVCISGDLLNPKKKYNLQYYLELVDKLVKLDIHVLGIKDMAGVLKPQAARLLIGSIRKNYPDLPIHVHTHDSAGTGVASMVACAESGADAVDAASDSLSGMTSQPSINAILASLEGTGLEPGLNVHHVRALDTYWAQLRLLYSPFEAHLAGPDPEVYEHEIPGGQLTNMMFQASQLGLGSQWAETKKAYEHANELLGDIVKVTPTSKVVGDLAQFMVSNKLSPEDVKARASELDFPGSVLEFFEGLMGQPYGGFPEPLRTDALRGRRKLDKRPGLFLEPIDFAKVRKDLGKKYGPVSETDVASWVMYPKVFEDYKKFTDKYGDLSVLPTKYFLSKPSIGEEFHVELERGKVLILKLLAIGPLSENTGQREVFYEMNGEVRQVTIDDKKASVENVSRPKADPTDSSQVGAPMAGVLVELRVKEGSEVKKGDPLAVLSAMKMEMVISAPHNGAVAGLVVKEGDSVDGSDLVCRITKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL26</accession>
    <name>A0ABR3ZL26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002171</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="309" mass="33419" checksum="4A9A1494F0569879" modified="2025-10-08" version="1">MGSNIAQKPGALLTIKPQSIPDASSKVFLITGAGSGIGLATIRLLESKNAAGLIIADFKKPSDKILNSLAKTTLFVQTDVTSWDSLLNAFKTAIETFGTLDGVYANAGLGELDHLFFNKIDGATGDPKPPNYANIEVNLKGVLNTVKLAVYYFRKLKVEGTIVMTSSMSGYETPGIPIYTSSKHAVLGILRAASLDLYEEYNIKMNAVSPGPVLTNLIDSFATRAATKYDGLSKDYTFENQGPEQPALAAAHLLLTQKEHGRSILVHAGRFRDAEEVYDSVRDQMLGSELGIPPVSDIGWRNLFRCIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL52</accession>
    <name>A0ABR3ZL52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="796"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="823"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="905"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="920" mass="97018" checksum="B3DF8964D3E27B28" modified="2025-10-08" version="1">MGPPETPAQCLCPLDRSDSNSRGNKKIKDRNFLDAHLDSIDDSNSLIDCTSHNNNNNNNNIRRSPSPISPFSPAAPPQHPVLRRSVSTTFYDGGDAQQCIDACRQGFFDSLSPLSASSPSLSNACSQLSSTTAQQELWQLYWCDSAFCGVWIDAGGSTGQDPNVDLIINQCQNIGYPSIYDPGPPPASYYCSSLLTAGPSANPCLNRAAVATETKTETATPTMTTTLATEHRTQRLTTASGAPITATSLSLGNIASAPAATGSRGASSSSDNDSSSASPSSLPSGPSAGVKGAIVVCVVVLVLLVVGVIFYFLRRRRNNMLGQQSYQHRGGGSGGGGIGIGGGSSRRPSHANNGSSATNGSIGLATRLRQQGQMLFYPGHGRGANRGEVPTPLISPANSCNSVRGVSAAATQISPRRAGAGFFAVFRKSQKSSPSDLRTPPRTVERAPRSILPSFFSRRQRERSISPPLTSLSPPPSPTQMSARGRPDAEAEDDGRPGHNRNRASAANSGSSYYGYYGYNGNFVPYYFPSSPICAPTTNKLEPRRERTPTIRPPKQTEQQKQEQQKKQDQKHGFYNFQRATDGGEITQTMERQSDRAPVPPLPPLPHSIFSTNMSDGFGPGTSRGLRSSYGSYSTASSTIIPATNLYGNAVTTNTVEPMLPLASISAAGSSTAATITPSNPGVTVSPVRPKRPHEGPLEIPDLVMPDPPPPPLFSPHNVGGRSFSMPATAFSVSSSGRRAPPRAPPKDGSILQRGPPPTRSLPPQPPEKQDDMDSIESLELPPLLLRDDDDEEGDTLSSWISPRRSPSHSRHSHVGAGSKPGAATASFSSMASSASILSSSTAETSTTATTVTSIPLTLSMSLPASSSPPPRQLFSYGSPSTASSSLTIRPAGSQNKRSASSADNDSLFPSRAILESEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLK0</accession>
    <name>A0ABR3ZLK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(A)-binding protein binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PBP1</name>
        <name evidence="3" type="ORF">Sste5346_001976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009604">
        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01272">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="2">
        <location>
            <begin position="80"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="538"/>
        </location>
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        <location>
            <begin position="569"/>
            <end position="578"/>
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        <location>
            <begin position="638"/>
            <end position="673"/>
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    </feature>
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            <begin position="964"/>
            <end position="983"/>
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        <location>
            <begin position="984"/>
            <end position="996"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1022"/>
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    </feature>
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        <location>
            <begin position="1030"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1087" mass="115096" checksum="68DCE8CBB8F1F4E4" modified="2025-10-08" version="1">MPPQRKDGPGGGQGGGSVRGQNGSRSGFRTDTAISNNRAGGERNLTRWVDDGPGAMDGSLESSSNSGGKWDQFAANERLFGLKTNYNENFYTTAIDRSHPQYSERLAVAERAAREIEGSTAMTSHVAEERVMDSVGEGQGDGDEEDKYSGVRRQQDFPPLASSARGDAKYTPPARRAPTGHSTVVGAPVDPAIISSQIKGGPPRKQQQQQQPPAIPKVEEPQTPAAAPRPAPPAVALSQQSKTPEPKAAEKPATEAKQQPASKAADSTADQTKSATASKPSSKPSTPAISSGTSSLRASATPNRTSLSPSAKASAFAPSTSAANSPAPPNVADNVESALLKEFKDFASQQRQQAEKARSNKIKADAQVKLQELRRFADSFKLSTPVPNDLISIIAKDPEKQRKIQEKALQNAEELAKSKTESAAGQRGSASSASSSKPAAASSNSTTPVASAAASNAGSNAAATASSTPSLGPSSASGPTAGGATGQENVRPLVSNNNGRPQGPPHAAHSASPSGVPNRHPNSRGGYMQQNFRQQTQPYRGDRSGPQHMSQGHNTGHLAERIRNSDQNQNRYNKNLNNHGPSHFGPSNDARVPPTGPANAADNNYSRRLSALPGGAHTPQKLNPTTHEFRPSPFAASFNPTHPSAGSSPRSTINHISTDQPHTMSSTATSVPTIPSPRVPSTVLIRRKAQNVSADKCDILTMIKTIKPPAGYQGRNWDDNDGLRPSYDTPLLWRQIQDDEKPDSTMHLKYTEYLDRVAFNAASMATPVQGHAMPHNMNQMPHQHQLPAHLQHGHMGPRPNQHMPPMPMHAGGGGPHGHIPQVSFNGSDDHRMMPSNSAQSYASPRMTQLPLYPQHVGSTPQMGYNQPAMPFMQNGPQMNQFRNYQNSPQGFMPPQNGPMMSMMPPQHFVVPGGMMGGSPQMGMYPGGPQQFMGPPGAGGAAGAPPPHQMGGSNGYPSPGRPVAPMMGQQGSQQGQPMYGQSPSIQFQQPAFNPQHQGQGGKTAMRGGYNNPGAQQYGTSPQGMHQYGPPHRGGGGNYSGKGYQGHNNHNTSYHHNGLPQQHQVNHANGPPAAHLNRQTGGDGAEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMU6</accession>
    <name>A0ABR3ZMU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stc1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Stc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12898">
        <property type="entry name" value="Stc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stc1" evidence="2">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
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        <location>
            <begin position="272"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="377" mass="41081" checksum="83F9FA92DBB04F10" modified="2025-10-08" version="1">MAERNGNGNGRPGQDSGVVSLFLRNDRVVQNTSRKIHCFAGGEWKPREEFSNRQLEKYTRSQGKEEISCRAHSTQIRRELKCEGPCAKWHPIENFSRSTRNHSKTWCMNCTDWQLSVEPGYAPYVPPSSLNEDEEEEEADDDEDDDGGIIPIDEVPGERIEDWIQGNPSELGDFDTVDFGTQPSIVGTGSEISRPSLLDTCNRELGGLPEALSAINLGTVPSAAPSYASVATASTVRGPASIAPRSYYTPVGGSLLMSDTDTASQTNRSVSNTLFSDNSRRTSGSQSNSVATSSAGGGGGRQTLWMENRFADLSRPLTQSATPSQRAETRNGWARPVQRRTNLVAPRYVASTGGMEVQPQGRTVYADADDDDSEDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMY9</accession>
    <name>A0ABR3ZMY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="175" mass="19729" checksum="49ABEC49B927BD7F" modified="2025-10-08" version="1">MSCMISQKYSASGLHDKQRNNTNLVPPLGRPVADISTDVDDNGAYWVTYWYEVDNKDPEQLQAVRLADIEGTLSGSILRLEKNLLDWSQVGHGADKDSYEIHGNDIRRLLSAPPLPEWPNDDEDVRKALTQLPRIDPIDMARHFVKRGKYVSEIQNLLAYKGGSCLDSPETNHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMZ2</accession>
    <name>A0ABR3ZMZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001841</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF1">
        <property type="entry name" value="ISOCHORISMATASE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="32"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="234" mass="24301" checksum="E517405524261F5B" modified="2025-10-08" version="1">MLALDPASYPAYAAECGDPSRTKVLGFGSRPALLLVDVCEAYFDQESPVAVPEADLEGVTESISALITAARSPSTSSAERLPIIFAQTLFVHPELRDAGLLGRKAPSHAVLFHKDAPVNKLAFPAALKEAAPLPTDLYHRKKYPSPFFGTNLASQLAALGVDTLVIGGFSTSGSVRATVLDAMQAGFRPMVVGAACGDGGGSEVHWANLMDAGAKYSDVVSLEAAIKALGGSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNL6</accession>
    <name>A0ABR3ZNL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PPH1</name>
        <name evidence="7" type="ORF">Sste5346_001227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="37325" checksum="362D513197D0057F" modified="2025-10-08" version="1">MDTNMEDVGRGPVDLTPPPALEPTTVPTVDGWIESLMNCKQLSELDVQRLCEKAREVLQDESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGPNPDTNYLFMGDYVDRGYYSVETVTLLVALKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNASVWKYFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLIARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNN8</accession>
    <name>A0ABR3ZNN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="20"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="588"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="784" mass="88106" checksum="8365002479B011A5" modified="2025-10-08" version="1">MQGKVAELRLELNSGGKKDKNFAAKKIALKKIVANMTMSNNDMVALFPDIIACMHIQSIEIKKMCFLFLVNYARMRPEIAIKAIPVLENDMENSNPLVRALALRTMSYIHVREFVEATVPIVKVLLRDADPYVRKTAAYCVAKLYDHDKHMVEGSDLIDRLNSLLRDDNPTVVASALAGLMDIWERSDAIKLTIDYHNASKMVAILPDCSEWGQTYILEALMSYTPQESTEAALLAERISPRLSHSNSAVVLTCIRVILYLMNYISDQKQITALCKKLSPPLVTLLAKGPEVQYLVLRNALLILQRRPEVLRNDIRVFFCKYNDPIYVKVTKLELIFMLASEKNIDEVLTELREYATEIDVHFVRKAVRAIGKLAIKIETAARRCINVLLDLVATKVTYIVQEATVVIRNIFRKYPNQYESIIGTLCENLDSLDEPEAKAAMVWVIGQYASRIENADVLLEDFLFSFAEEPVEVQLALLTATVKLFIQRPTKGQELVPRVLKWATEETDNPDLRDRAYMYWRLLSTDIEAAKTIIMGEKPAITAESERLDPQTLEEMCLNVGTLATVYLKPVQTVFRSARPRRLIESPALQRPLNHSANASLPLPPSQQQQQQRQQQLLQQQQKLQQQQQQMLLQQQQQQAAIQQQQQQQMFAQQQQMQPTGQPGQPGTAADLLYIDTNKSLSMLGHGGQPSDIDLRSREPGLAANGNGIANGQFNGNNGLASPQSAVDEADAYFSQMRIQEPTVVAPDSFGGGDGGNTGYLVNQYAPQTAYHPQQGHVNDLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNW7</accession>
    <name>A0ABR3ZNW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3 7">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GUT2_2</name>
        <name evidence="11" type="ORF">Sste5346_001375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00978">
        <property type="entry name" value="FAD_G3PDH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="99"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="10">
        <location>
            <begin position="509"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="686" mass="73671" checksum="14A75EDE57B0967C" modified="2025-10-08" version="1">MAWRLPHVRRPLLISAAAVGAVVTGGTLYAVTRKHAPRVPMPIVPVQRDSAGAIQPPAFRSAKSRAEQIADLRSSHPQNQTTDASSLTTSSSQKSSEYDLLIIGGGATGTGIALDAATRGLKVALVERDDFSAGTSSKSTKLVHGGVRYLEKAIWNLDYGQLELVIEALGERKTFLEIAPHLSSQLPILLPLQHWWQVPYFWVGTKAYDLLSGSQGLDGSYWLGKSKAVEKFPLLNSDRMVGGLVYYDGQQNDARTNVSLALTAMLYGATVVNHVEVTSLEKDAAGKIIGARVRDTLNENDDSFTIRAKGVINATGPFSDAVEHMDNPAKPTMISPSSGAHIILPGNICPNGMGLLDAATSDGRVVFVLPWEGRTLAGTTDNPCAIERSPEATTEDVDFILKEVRKLVSPDAPLSHKDILATWSGIRPLVKNPNSKNTESLVRSHLVTVSPSGLLTCAGGKWTTYRQMAQDAVDDAIRAFHLNPERGIALEAVGSSATSFTPAATTGACVTKSVPLIGAHGFSPALPAQLKEVYPAVDADVVQHLASNYGDRAWSILSSSASSPSARLIPTFPITEAEIRYGIRNESACTAVDVLARRTRLAFVDVQAAREALPRVISILGDELKWSEATKEREFEQSLMYLKSMGLDQVKAATQQTQTVKESVRKPAATPAVDWDVEKTGNNVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPB1</accession>
    <name>A0ABR3ZPB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF26">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_5G13940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049813" description="FAD dependent oxidoreductase domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="401" mass="43161" checksum="9E6347F94A9C3486" modified="2025-10-08" version="1">MPVKIAVIGAGVIGLSAALRLLEENPDGSIEVTIVARDFPAPAETFFLDQAAHINYTSPWAGAHNRWVLWVADGTEAAAAAERDHGFALATFRHMQGIVAKHPEAGVTFMPGIEYLEAPGPEYTQLGDEAIQKQLGLQEENLDLGFRILDKDGGDKDAPFPEGVTWGCAYRTWCANPMVYCQFLLRRFVAAGGKVAKRDLRTPHELFAPAAPDTALDKDKTLGAPAGGFDLVVNCSGNGFGDDPHMFITRGQTCLVRNKCDATVTRQNADGSWTFSVPRNFDGGTIIGGTKEPDNWDVAPSMANRERLLANFAKTYPKVLEGSKSGTFEVLADVVGRRPTRRGGMRLEVEDVVLEAPAAGTSSDDKTKKSVIVHAYGVGGRGYEISWGVAGAVTELVKKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPH3</accession>
    <name>A0ABR3ZPH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lon protease homolog 2, peroxisomal</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_001043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03121">
        <property type="entry name" value="lonp2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027501">
        <property type="entry name" value="Lonp2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="11">
        <location>
            <begin position="789"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="281"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="484"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Microbody targeting signal" evidence="8">
        <location>
            <begin position="990"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="882"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="925"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="546"/>
            <end position="553"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="992" mass="107018" checksum="15B745EA35D8ECB4" modified="2025-10-08" version="1">MARSQSPALPILPLPKGMILFPGILQRVPATSDRPDIPALLASMYARAAAADPADNEGNTRAVNEVPVVCVPMASPLVGPRGQLLINGKEHNSVNSTKTPDFVAGKSTKADLFSCGVVAKISKIEGRAAGEFTLHVEGRSRVWIDKFTQEQPCFEGKVTLCPDEIDVSDAALYEVFQRLKAASRELAQVLRVAAIIAPDRPHARFTPLLARRLDAFILNKSIAEAGVLADFMTNIVVASYEEKLQVLALVDVKKRVARVVELLERQVGNIRNNVKITTVTIDSDGNSDDPNGGGARIWDPLKQSLPQPKNGQGMPFNILIPSNGNGMFGSGMGGPGGGNGFGGGNGFRGGPGGPQTPESQEPDEVEELAKKLEAAELTPDAAKIANRELKRLRKMVPAQAEYSVIRSYLETLAEIPWKTVTDDRLGPGTLAKARAQLDGDHYGLEQVKKRLLEYMAVLRLKQSINEDIEAQTRDAQRALELAKATAAAPTNDASPEATATVSAEEKKEQEVKASAAQAEVRAADEKLKAIGARRMTDRSPILLLVGPPGVGKTSLARSVAASLGRKFHRISLGGVRDEAEIRGHRRTYVAAMPGLIMQGLRKVGVANPVILLDEIDKIGASNNHGDPSAAMLEVLDPEQNYTFQDHYLSVPYDLSRVLFIATANSLDTIPAPLLDRMEMIHLPGYTTLEKKHIAMQYLVPKQIRVNGLTDEQVGLDETVVAKVIESYTREAGVRNLERELGSVCRAKAVEYAEAKDSNNLEAYRPQLTVEDIENILGIEKYEDEIAETTSRPGLVTGLVAYSSGGNGSILFIEVADMPGSGRVQLTGKLGDVLKESVEVALSWVKAHAFELGLTQDPVEDIMRQRSIHVHCPSGAVPKDGPSSGAAQAIALVSLFSGRSVPPSIAMTGEITLRGRITAVGGIKEKLIGALRAGVKTVLLPAQNRKDVRDLPQEVKDGLEIIHVSHIWQAIRCIWPEAQFPGAEHYPAVESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPP7</accession>
    <name>A0ABR3ZPP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF2">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="378" mass="40977" checksum="4AC0AA83C2B13789" modified="2025-10-08" version="1">MPAATLMDLKEEPNAAVDEPIAASETTEGSASNPRKRKKSSRACDFCHINHQPCDNAKPRCSYCERHGKSCLYLRPQKKRGPAQGYRSALHSMRESAAAWGAALNLIPSLGPVIEGYLQKEEGKRLIRAIKDPQQQEFFIQSWQQSSVFKSFFGDEESAENAEAGEAADAPFAPRSSSTAADSATGSSTDTIVPSAPPPYLPPPPQTASADGVPLDLFSMQMPPSLPQPPPSLQHSSSSLSYSPHQHQHPHHPQQHHHQPAPLPYDPKLESLLHPHPGDISHPHDHSMLSSPDGMGGGLGGIHTSLSDIVARDAARATTSFSQTLGSLGFGPDETLNDFLNISYNLDPTDTMADQDPLLGSELDQKAYYELLMGRQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPU1</accession>
    <name>A0ABR3ZPU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal lysine N-methyltransferase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RMS1</name>
        <name evidence="6" type="ORF">Sste5346_001416</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="26"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="546"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="548"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="585" mass="64890" checksum="5DBD9CAE56623D13" modified="2025-10-08" version="1">MSDDYLQPARAFLEWFRAWPGTTFHDDIEIVDLRARGAGRGIIANKDIPVDTVLFTIPRKAIISATTSELAKLIPSIVQGAEAEEKPESEKKEDKEGEDDEDEGDDDNNAQDPWTSLILILIYEFLRGPASPWKPYFDVLPAVFDTPMFWSADEIKDLQASPVVERVGREEADEMIRSKVLPVIRAHSSIFFGEGVAELDDDALVQLAHRMGSTIMAYSFSLEKDDDEDDDEEKKEEKPKGDDEDVEMKDGDDQETHVHENEHEHGPDCNHDHGDDSDDDSEGAGWVEDKDDQLPLGMVPMADMLNADAECNAHISHGVDALTATAVRPIKAGEEILNYYGPLSNGELLRRYGYTTDKHAFFDAVDLPWFLVQLHLARQLGLNAAETVKVAEAIDADEFEDPVMLDRDFDEDEETGELKGVQGDAVLTELPQILRRQARAFAKVALRQQQKRREKALAASKKQTGKNGKNDKTHPPKTEKEVVAAALAAAFTERLAAYPTTLAADEAQFAETPVGSRLHSALRVRIGEKRLLTEAVALAKADLTAAKAEAKAEAKAEKAAEKSGKKNDRRDGNDDQPSGKRQRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPX4</accession>
    <name>A0ABR3ZPX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional activator of fatty acid utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CTF1</name>
        <name evidence="8" type="ORF">Sste5346_001195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF3">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="328"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="634"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="691"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="883"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="636"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="762"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="917"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="965" mass="106363" checksum="198E65AB7BD3220C" modified="2025-10-08" version="1" fragment="single">MEIDSVEDGVQPQQQQQAPAPASPFNAAGQQGAQSAQEQANQSAANHLSFRRHAMPERSASKDSDSERGDGSDDKSPQASSVAASNASNASGVTPSTTTTVGNFRPPAIYHTAEGTPSSAVTELQAKQQEADKSTYVNILMKPRFTRAPITEAGRVAYLGESSNLTLLVHDQAGSTDVVHYPLPENVRGSRARLTELDNVEIEILHQRGAFLLPPRDLCDELIEAYFKWVHPIVPVINRTRFMRQYRDTNNPPSLLLLQAVLLAGSRVCKNPKLMDANGSTTPAALTFYKRAKALYDANYEDDRVTIVQSLLLMGWYWEGPEDVTKNVFYWSRVATIVAQGSGMHRSVEDSQLSTTDKRLWKRIWWTLFTRDRSVAVALGRPVHINLEDSDVEMLCEDDFNEDEPDQPSEYKPDPLQVHFFMQYVKLCEIMGLVLSQQYSVASKGRQKSPMDLAHSDMALADWLQNCPPIVCWNAASRNFWSGLLFSTYYTTLCLLHRAYMPPGSSSRFGDESAMYPSRTIAFQAANNISHIIDYMNSSEQLRFCPAFIVYSLFSALIMHVYQMRSPIPSIQMVTQDNLQICMNGLKEVSKVWLVGKMVYALFESILGNRTYEDRLRRAAGQRHHKLQQSFTGLDQHAAAQQHAQHQAQRQAQQHAQQQQQQQQQQQQQQQQQQFDFSKRKYDDMAIDFSVNTPQPQESYERSRPQTPSMTTAKVEPGTGAAMPPPSSITSPPTRQAGDTFMGGNGPSNAPGGGDGGGTASRPQTRPHTPFNPSYSVPGTPPDLYLVTRNSPILSQSVWENFQPDQLFPDGTGFSTMFPPTMSPGGTTQTLDPNMINAGIPPNQHPQQSPFGQHVTPVAPGDVNANTSPMQNPSMLAPGMPGFQQGGNNGQQQAQQGGAGANGNGMWNTKMDGTLPDGQSPSDSWSTGSVGGQPVPSTLNVEDWFQFFGINGDASTMNLDLSSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ15</accession>
    <name>A0ABR3ZQ15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ASTRA-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">asa1</name>
        <name evidence="9" type="ORF">Sste5346_001323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the ASTRA complex involved in chromatin remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ASTRA chromatin remodeling machinery complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ASA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="493"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="443"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="53941" checksum="6CEAF5F71883D0CC" modified="2025-10-08" version="1">MATTSIAAARPPAQPTAILRGHRAQVHAAVFARLDRAASSDETMTADTRLVTGDSDGYVVLWDLAIVRARGVWRAHQNSILGIAAWDDAGQIVTHGRDHKLVVWQVGVADEVRLSAVLPLDQESKTSSKESHPQPWMVHVLDVNTMNFCAFAWCGLVGSVAAVTTAAPTSTDTQLTTTNGPPTERLVAVPNTLTLEAADIYHLPSQRRINTVRLGTKEGMIMALALFYAPVSEPTDDSQRTLVLIAAFENGVVVLALLRQGADGPAEIIYRAQPHSQPILSLDVAPDCSYFLTSAADAVIAKHPIRVPAVKKTATAAPAPPRPSAPVGPSPPPPAGKTVSLLSAALAKEAALSPSPSSSSAPPKGTAPSAPIEVETQPLTIINTKHAGQQGIRIRDDGRLFATAGWDARVRVYAAQTMKEVAVLKWHQTGCFTVAFAPVVRPDTEGEGNNTAAKPTEGPSAGNTTTTLATRSTRRDISVKERRLRHAVTAHWLAVGSKDGKVSLWDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ61</accession>
    <name>A0ABR3ZQ61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001207</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="385" mass="42639" checksum="B663B642DEBBF3D0" modified="2025-10-08" version="1">MLSRAAIRQSRRALFTTPPTAIGGQIQIARRAFLSTESTTTSIPSSQTAPPPPPSQRQESTAARPDRAANSESADAAQRQQWGAKKEISDEIARNFIVKKTVHRKTKRLGSTIEDRYVPQELINHPPTPKDVTLELLLASQTHMGHNTAMWNPENSRYIHGIRNGIHIISLEQTALHLRRAARVVEEIAYNSGLILFVGTRRGQSDIVVRAAELAGGCHIFDKWNPGTITNRDVMLKGASIRMVDEQDRDISDEGFRPHLMDHRALAPDLVIVLNPLENHVLLRECAQEAIPTIGIIDTDADAARVTYPIPANDDSLRSAALIAGVLGQAGKLGNKRRLRDAKDGLVTWENDTDVLGYLDKQSRQGEQKRPRKTPRWILAGGKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQK3</accession>
    <name>A0ABR3ZQK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001133</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="654"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="697"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="375"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="606"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="743" mass="82052" checksum="316314751D6058DD" modified="2025-10-08" version="1">MYGVLAASVGVTILSFQEHRRNIRPSDTIVLYLVATLAIDLVSLAVPLRFGWPSIFYRATCFEAVVKLVFLVLESKSKKSVLRDELHDLPPEELAGVLSLTYFWWLHDLLSLGYHKILSPEDLPKIDTKLDSDPLRQRILASWDKRGSWIVVTAVFVYFGLMTSTAIYRHLLNRIEIMFRGALVGIIHQKALTGRSHAYDDGKALTLISTDAVELEGSAEVLHEMWAFCLEAVIGFSMLAMEIGWLWPLPTAVEDVILQLRDNELIAAKGVRWINVLYNSSANALGLFSPVITVALYAIISSANGKEFDTRTAFTTTAILSMITHPINMVMTILPRIAASMSSFERIQAYLLRPSVDDKRAFIDSEDSGQPPSAVVFTDVAIGDQQSGKSILESLNFSIDKGSVAIINGPVGVGKTLLAHTILGEVGFQKGTVSVSSLQMAFCSQTAWLPNRTVRECILGLDGDVLVDQMRYERVLEACSLNEDLEELHDGDETVVGTGGQNLSGGQRQRVAIARAVYSHHDIFVFDDSFSALDGKTQGAVINNLLGLDGLLRNNNTTVLWVANNKSYFHLADKIVLLEDGTVKYQGDFQHSNETTLQQIFTETAARREDSDGLTENDTTQAKTSSPSRKVSSNPPAATPDYQRKDGDLSLYKYYITSAGIGNVLLLVLMTATFASFSTMPALYLKWWTESKSDNTVLYALGYVSMMVVAWLATSLLKWTDIILVAGRSGEILHRRLLQAICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR76</accession>
    <name>A0ABR3ZR76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">POR1</name>
        <name evidence="4" type="ORF">Sste5346_000891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00558">
        <property type="entry name" value="EUKARYOTIC_PORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="30026" checksum="A8779E1FF7AA35B8" modified="2025-10-08" version="1">MSVPNFSDIAKPANDLLNKDFYHLSAGTLEVKSNTPNNVAFKVNGKNSHEKTTNGTIEGKYTDKSLGLTVTQTWNTANALESKLELADSLAKGLKAEGVFSFLPATQARGAKFNLHFKQSSFHGRAFFDLLKGPTANVDAVIGHDGFLAGASAGYDVNKAAVTSYSAAVGYQAPTYSAAVTASDNLSIFAASYHHKVNSQVEAAAKATWNSKSGNAVGLEVATKYRLDPLSFVKAKINDRGVAAVAYNVLLREGVTFGIGASFDTQKLDQATHKVGTSFTFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR96</accession>
    <name>A0ABR3ZR96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30966" checksum="37C2CD18DA0B8CC2" modified="2025-10-08" version="1">MAEDKAPTVDGTNGENKEPVEAVGNNEKEAEDNQEDHDHEEDIERFPPDQEAGLLAEANEHKKEANELFKKSQADGALTAYETAVAILPSYLYYDFALLKSNMAACYIKMSDWKEANRTATEALDALDKEVKRIEKEKANPKKEVLANGDLVDDDDDTSVEEEIISEGAKHAARPPPPPKEPTPPPKPVGPTDQDILRIRSKILLRRGRARSELGGWANLAGAEEDYKALSAMPAGTLPATDVQLVKKQLKDLPARTNEAKDAEMGDMMGKLKEVSYFQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSG8</accession>
    <name>A0ABR3ZSG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="307" mass="33730" checksum="4D5A9B767CAAEBF7" modified="2025-10-08" version="1">MAAEQTTADAANFAKYLPNVKLNDGTQIPTIAYGLGTANYKGTRTEFDQKIVDDTVAAIKAGFTHLDGAQVYGNEEELGAAIKAGGVPREKLYITTKYDPKPDGTVEESFALSLKKLGVDRVDLYLIHKPFWNGITDEQIQSRWAELEVIQASGRASSIGVSNFLQNHLEALLKTAKVVPAINQIEYHPYLQHGGLVAFHQKHGIATSAYGPLTPIVRAKGGPVDPVYATLAKKYGVSEGDVGLRWVIDQGIVAITTSSNTERLQNYLNRLTSFNLTPKEVEDISTEGDKKHFRAFFKTTFAEDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSI4</accession>
    <name>A0ABR3ZSI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="7">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GSY1</name>
        <name evidence="9" type="ORF">Sste5346_000464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03793">
        <property type="entry name" value="GT3_GSY2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="3 7 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="706" mass="80320" checksum="DFA0C8B01F196F8F" modified="2025-10-08" version="1">MAQDGAREPREVKNHYLFEVATEVAHRVGGIYSVIKSKAPVTTAEYGDRYTLIGPLHRESAAVEVEELEPTNPELAATIDSMKERGIQIVYGRWLIEGAPRVLLIDTKSAYGFMDEWKADLWNVASIPAPPSDEETNEAIVFGYLVAWFLGEFVCHEKKKAVIAHFHEWLAGVALPLCKKRRIDVTTIFTTHATLLGRYLCAGSVDFYNNLQNFDVDAEAGKRGIYHRYCIERAATHSADVFTTVSHITAYESEHLLKRKPDGVLPNGLNVTKFSAMHEFQNLHQHSKEKIHDFVRGHFYGHYDIEPENTLYFFTAGRYEFRNKGVDMFIESLARLNHRLKSAGSKMTVVAFIIMPAQTHSLTVEALRGQAVVKSLRDTVDVIEKSIGRRIFERSLKWHEGDPLPDEKELITSQDRVLLRRRLFAMKRHGLPPIVTHNMVNDQEDPILNQIRRVQLFNHPSDRVKIVFHPEFLSSANPVLPMDYDDFVRGTHLGVFSSYYEPWGYTPAECTVMGVPSVTTNLSGFGCYMEELIENSSDYGIYIVDRRSKGVDDSVNQLTSVMFDFCQKSRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRAYPDSFASDDEEEDYIPGVEQKISRPFSVPGSPRDRTGMMTPGDFASLQESHEGLSTEDYVAWKLPEEEDPDEYPFPLTLKTKPTGGAASPLDGVILNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSI7</accession>
    <name>A0ABR3ZSI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YKT6</name>
        <name evidence="13" type="ORF">Sste5346_000430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="140"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1903146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="200" mass="22540" checksum="1421E3369C175040" modified="2025-10-08" version="1">MKLYYIGIIRNEGGQNKSAELVAEKDLSEYSRFTRSSIGEFMTLFSKTVAERTKPGQRQDVEEQSYTFHAYGRSEGICGIIISDQAYPPLVAHQLLGKVVDEFLASCPRSAWATGEHPSVSFPELKEYIVKYQDPQQADSIMKIQQQLDETKIVLHKTIESVLQRGEKIDDLVAKSDGLSAQSKMFYTQAKKQNSCCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSK9</accession>
    <name>A0ABR3ZSK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="57685" checksum="6520E7517CF4F2B8" modified="2025-10-08" version="1">MTGFIFVDGRQNDRSTQRRMRRHVMKGKNAGKTLQRASRLPPGKQLMRRKDESAKPALPFMPSYAFTTSTSTGASLTLSEQLTILQRLPPAATFHSPVAMTAYAWQVIDEYFNGTVERVYAPSFGIASDTAKPLWFQSIFADEAAYHCTLALMQASNEAVLGAATGCVLASSGVAYAHYVAESLRQLKRRLAGPKALANSTILLVLMFISQEQMRHESKNARVHIAGLRQMVALRGGLAEFETRGVDRPLLIKICKIDIVYALQFGTPPLFYRDVLSSVTAKLDIGGRCAQEATSTAETHHSSLSERQPDLYSMLVDVMAVALLFEDELPQRPIDIFTFGDIFSSLSYRLLKAGLDTFPGDKVDELYHLGMTMFSMALFLRFDQGRLLDYQPIGRRFKAVVEDEGVERSQDKSERSEDQKEDETCFWVMMLGGTWTRGDWSGSGVEVKAELGGDCPGRQQKARKVRQVADRLGLSSWEDARALLAKYPWLTVLHDKPGRELWEASREVQEKDNGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSS8</accession>
    <name>A0ABR3ZSS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="76"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="383" mass="42320" checksum="7CCB339F36664B5E" modified="2025-10-08" version="1">MSGLLSLVGWSFLPNFVTGWAQSIYYSLTIRAGDPRPMPGTPRFAEHRRRIHILVVALYLAYTIYEADYDMRRAGSFYRDLGVPLGATDREIKSRFRRLAALHHPDKAGSAGADEGAINAYFVHLKTASDTLLDPARRFAYDRFGPISVAWATNNSNNGANRCSTVYDFVSMGVRTLAPYYTVAAAALYGLGLLGYLTWGRYERWLVLTSVLVFELHAISRPYHPQILTDVLNPLFALLVPQHGPYLPFQAVQLARKLSLTMYIGFSQIGPLLGADTRSGQIVTADSEASPTGPKGATDPALIAALDRLEATSRSLDQDATRLLEMEMAPFVGQDEVLSNVRGKIKEWLVQNTIRADPMVRDAVGRSLQRRRTDAPAGARGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT86</accession>
    <name>A0ABR3ZT86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rhamnogalacturonan acetylesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046656211" description="Rhamnogalacturonan acetylesterase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="29463" checksum="E27ECD6BF56A29F4" modified="2025-10-08" version="1">MKTTTALTLAQATMSMAAAVTTSAAAPTIHLCGDSTMASMSGAIQGWGQYLHYSFDPTRYTVLNSAIAGRSARSFTREGRFAAVLKLVQPGDWVVIEFGHNDGGGLGSKDNGRSDCYGAGNETCQTTYDGKAETVETYPTYLKQAGAAFLKAGAKLILSAPTPNDVWSDKGVYSWGPDRFAYYTMLAAEELGGIKAGVYFVPHGTYAAQALKALGSDVVHKNYPQDHTHTSPYLADVMAGAFVLGLTCGTSDLGKATLNSTAALSGTFLGGCISYNSTVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU12</accession>
    <name>A0ABR3ZU12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="175"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="289" mass="31928" checksum="7E605E3C8DD811E9" modified="2025-10-08" version="1">MATVHGNVLRMGPASDQWQYHRKERLYDLTRGYDKNGKSDRLPVEDAAVTIRTTAGPENTNIALAPSRTALVIVDMQNFFLHRRCRDHPTGRAAVVPTLVAIESCRRAGIRVIWLNWGLTEESLATIPAAIMSGFSRRMVLVDADEEPVRSGLGVDPGDGCGLWLVKGEWNSNVYEGEVEGDGRTYDLSAAVRPDLGDVLCDKTRMSGMWSEDEPLRRYLAEQTSVRTLLFAGVNTDQCVLGTLTDAYNAGWDCVAVADCCATTTPHGQELTMLNVAVRFSFTIGWIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFX4</accession>
    <name>A0ABR3YFX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000136">
        <property type="protein sequence ID" value="KAL1887206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="95"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="668" mass="74792" checksum="39E83EEC8CAC017A" modified="2025-10-08" version="1">MSPRLPRSHRTSVHSSSQLFGIEGRFRGHFSGPFVPRPAVTQKDMRPYFRSRRIQKGTIDRPELRTKDPRWIWMNIVPVVGILCGLGIIAVLAYLGYRSVVNHTYCLVFTDDFSSGINPAIWQYEIQTGGYDNGEFEITTADVENVFIRDGQLVIRPTLQTEEYLQSTTVVNLTSAGTCTSNVPGDCILQVNNTAEDIVMPVKSGRLMTKNTAVIRYGRVEIEAKLAAGQWLLSQMIMMPAENYYGSWPASGEINIGISRGNNATYNGGNGNQRVQSNLYWGPDTTEEPWQYTTGTRDALHSEYHDRFHTFGLEWTEKYLFVWIDYRLAQVFYTKFHPGGFWALGNFPATYSNGSLIQNPWTGPGTGPATPFDRPFYLALGVGVGGTSGWFDDGVQGKPWSDKSTAPRLDFWKARDQWAPTWNESGAGEMIVRKVTMWQQCDDGATDLRNIASTFYSSSKRGLVFVPNANFPEDNNVWVQNGSDLTWYYNYKSYPSSEYAKDTSFNFVPMLWGAPSSFNDTTFLDNVTAQITHGSNITHVMGFNEPDGTSDTGGSGVPPDDAAIYWIKQIQPLKKLGVQLGAPAVTGGLSGFEWLANFTKACEGECTFDFIPIHWYGNFDGLQNHLADVASAYPGVHQWVTEFALDDADLNTTQQFFQDSVRFLDENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH42</accession>
    <name>A0ABR3YH42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ATG9</name>
        <name evidence="21" type="ORF">Sste5346_010081</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)</text>
            <dbReference type="Rhea" id="RHEA:67920"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 19">Preautophagosomal structure membrane</location>
            <topology evidence="3 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the ATG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000113">
        <property type="protein sequence ID" value="KAL1887633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0072">Autophagy</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 19" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="595"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="86"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="755"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="851"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="894"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="931"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="942"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="965"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1887633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1007" mass="112559" checksum="03BFF0A0D61AFDDF" modified="2025-10-08" version="1">MSSNIFSRFNSTADRGGRPFYDSAGRNESDTAEGYDVEERAGLAVDEENLNEQFHDYDLENADGLGIDASRATIESAVPPTIAGGAATSAAAAAAASSAAGAAKQSAASRGQRGHRNPSHSRWGDDDGDNDDVPGSLLVEPQGPGADPFPPMLKATPLRSNPSDRRPRGPGGAIPGPSTKKNRGQWEAIQKQQRLHGNDIGDAGGSSRGGYGGPPDPVGGRATSDGGSQPGHALLSYFTSRGGGNHKSTAYDRAMWRWVNVSNLDNFIRDVYAYYRDSGMRCILLARLLHLVNAAFVAVFLTFLTQCVDYSKIRGSTRMDQILVPQCTKNMSWIWNFGLWLFAFYFIWKIMQFFIFDIRRLINLRDFFVHLLQIPEHDMQTVSWQDVVVKVMALRDQNPKTATNMTRVQREWIGSQSKERLDAHDIANRLMRRENYLIALFNKDILDLSVPLPFLRNKQFLTRTLEWTLWFSVLDYVFDERGQVSQEFLKSSRRSQLSARLRSRFLFAGFMNLLLAPFVACYLVVVYFLTYYNEYQKNPSALGARAYTPLAEWKFREFNELEHLFEERLNMSYPFATRYLDQFPKRKTEQVAKTVAFIAGSIMTVLAIASLIDPELFLGFEITHDRTVLFYVGIFATVWATARGMITEDNSVFDPEYALRNVIEYTHYEPDHWKGRLHSFDVKMEFAELYQIKIKIFLEEILSIFFTPLILFTSLPKSSDQIIDFFREFTIHVDGLGYVCSFAVFDFNKGVGATSNPKRQEQQSLQPDPLGAGGGDVRDDYYSTKHGKMAASYYGFLDNYVINPKTGIPGHHPPGGGRHHQGQFHPPPAFPGLNSPTLAADMQNSRIRHRGLGGTGARTPRFGPSSMAQPSPMASILLDPHHQPSTIPYANRSMHRSRVPGRYGAGGPGESYIVEEPTMEDSRVGTSAGVARDDSYRDDDSLQPNQQAQANSGEFPSGPGMLDESTWQTSPPTGLSRENSGVGEDADVGVLGLMYQFQQAHQNHRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH65</accession>
    <name>A0ABR3YH65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000125">
        <property type="protein sequence ID" value="KAL1887360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="248"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="692"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="755"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="755"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="773"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="851"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="933" mass="99590" checksum="603069B5D26915C2" modified="2025-10-08" version="1">MNCKSCRKRKIKYAVPKKRGPKTDILEALLKRVDGLEQQLKDQKEKGGDDGGAEGSEASAVGSGSGSGISPSSDESPGAATSSANAGESSTSPISKAPATDVPMTEQPRKQSKSKGPEMSAPAAKQKKDTEATSSHRQDNTPPVQVDALLHTYFTRSHAKPFHILDESSFRQRLQLGQIPSYLLGSVCALASRYTPNPHGYQAAVRLGEDYALRARAEIDVDEPSIDCLQTLLLLALAFVASGKGKKAYMLLSNATGMAVALELHREMDANARVMPVEREMRRRLFWTCYLLDRFMACGSKRPSLIHDSTIFLRLPSWLNSATSMPVDGDFFQTASNLQYLQNGAGKKLQGGSGMLIDISRILGITNRYLAAGGVKGDSHFPWHSLSNLSKIRQDLDVWATGAQDIFSSVETLFSQPDATVLVMSKLIYHLIHCLIYRPFLPVDLAELSGTGQHQSWQIEATNMCFLHANAIAELTELGKQMPQIEWPGFVGYCICTAGTVHIHGAHYNKNSAGSEMGIFAASAEFLSREMQHMAEMRHAWACVQHHRQTLQSIYNAHTELVKTVSNSPMRYSPVFQLEDFFDRYSNIGGPGGPSFNFDASNLILADVLIDFAPDSYAGHNLYTTKVGFRDASNDTTNNNASSGGDGAMDVVIPERPSLKRRKTVPAIVLPDGSGTNNMTGGMQAPHNLQTPSLQQGPYSAAPFSSHNNTGLLASPSTMTPSISHATTSLNERMMGNDNQSAMGDMSTFSLNQQMGMQHQTQGQQQQSQQQQPLPSGTPFSPSFNFATLAGNATVSSAGSATMAGANRGMGPGGMGQGATHVELSGYDPMFATMPANAFSSPSPWTVDESGGAGGGGGGGSGNAAGKQAQGGGGVVLQHSPDGRSNDGSAGGTVAGEEKDPFLSLLEQLAENEYARGPGNELDFFLAGNAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHF5</accession>
    <name>A0ABR3YHF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="74"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="591" mass="62483" checksum="8599022535F7537B" modified="2025-10-08" version="1">MAISGDEALPGDKEIEQSTFNSGSLSDGPAEGVLAAPNAATDPTATGEADVTTTAPTGEPLYEDGRSTLQTVLIMVSLCSALFLGALDVTVITVAIPTIAADFKSTVGYTWIGSAYLLSNAATAPSWGKISDIWGRKPVILGAVAIFWIGSLLCAVSRNMTMLIVARAIQGIGSGGIIILVNVCISDLFSMRKRGQYYGFTGLVTRLVWRWCFYINLPISGAGFILLVFVLKLHNPKTPMRAGLAAVDWLGSFAVSAGTLLVLLGLTFGDVMYPWKSGAVISMIIIGALVLVAFAFIEARIARYPIIPMRLFNSRVAVASFVCCFFHGIVFVSGSYYLPLYFQAVLGATPLLSGVYVLPYSIGLSITSAAVGIAIKKTGKYLPFIIAGFVLLTAGFALFTNLGDHANWAKIILYQIVASLGVGPNFQATLLSLHTTVDRRDVASATATFGFIRQMSTTISVVIGGVVFQNQMQQQHDKLVASLGAEAANLLSGSNAASSVDVVASLLSGPALQTARSAYWVAIRTMFIMYAALAGAGLIASFFITQSTLSTEHVDHKTGLEGMRGREDDEKAAKKAKQTDGDGETGVKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHM5</accession>
    <name>A0ABR3YHM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FMN hydroxy acid dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000128">
        <property type="protein sequence ID" value="KAL1887323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF149">
        <property type="entry name" value="2-HYDROXYACID OXIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="78" mass="9008" checksum="9CB0ECA6D64756C1" modified="2025-10-08" version="1" fragment="single">MASKPQLYSIDDFEQYAAEYLPKAARDYFNGGSQDSVTLRANRAAYAKWYIRPRVLRDVSSLSPQRHVFQDGHEIPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHZ9</accession>
    <name>A0ABR3YHZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000119">
        <property type="protein sequence ID" value="KAL1887458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF171">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="103"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="235"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="590" mass="62006" checksum="90F7661FC28EB1FB" modified="2025-10-08" version="1">MSLASLSDPTVNDPIVTRKRLHGVAHKNGFQIAPQHEAAYLLGLRSSYAIATQIDALPDYIDPRMSVVPTRNGGDTAASAREYSRPDPADNALNAWCHQCDVAAVEPESSLLKGRAIVVKDTLAVGQLPQTLGTLPEFISPSTEYPISPIDATAVRRLLLAGANLKGTTTCEHFSLSPMSYSSIWGPVHNPWQKGYNSGGSSSGSAALVGAAVVASAKAEGATGSDGTEFTFSAGITLAIGGDQAGSIRVPASYCGIYGLKPTFGLVPYTGIAGLLPMIDYVGPLATNLDDIALCLTVLAGYDDLDPRMGPESPLRENVIAYHEELAKFTESLKTAKPLKVGLITESFAIPGTNADNAACVREAARKHFSAMGATVGDVSVPLHSLGAAIWTAAVRNQMATHAFGGRAPDVLGHDLPHIAPNASAHKSQKFYDVVTKHNPSVVLANMVETLLGEELPYAAQNKARRHVLQLRAAYDEALKKYDVLVTPTAPAVAPPHPNMEHRDINGQSSVERLLRLAAGSINNTAPFNASGHPAISVPCGWAPSLNGDCMLPVGMQIVGKRFNDLGVLKAARVFELGGGRLGSRPSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIN8</accession>
    <name>A0ABR3YIN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BNA5_2</name>
        <name evidence="4" type="synonym">BNA5</name>
        <name evidence="7" type="ORF">Sste5346_010047</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="6">
        <location>
            <begin position="108"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="159"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="468" mass="50506" checksum="680162AD42976FD3" modified="2025-10-08" version="1">MSLPTPTRDRARLLDQKDGLRRFRSEFAVPSTSQIHSNTLGALGDTVGASAVSQPSTYLCGNSLGLQPTRTSTRIQQHLSTWAAQGVQGHFKPMADSPLPTWLDADAKAAEMIAPIVGGEASEVAVMQTLTANLHFLLSAFYRPEASGRHKIILESKAFPSDHFAVETQIRHHGLSTKSSMITVEMPSSDNTAIATRDVVSAISQHAADTAVLLLPGIQYYTGEFLDIPAITDFAHAHGIFVIWDLAHAVGNVPLRLHDWNVDAAVWCSYKYLNSGPGGIGGLFVHARHSQVTRSFVDEQSDTGFTNRLAGWWGNDKATRFVMATKFHPVPGAAGFQLSNPSILDITSLCASLEVFQEAGGVDVLRTKSVSLTGFLEELLNALPSDVRGKFRIITPSDPAHRGAQLSLLLGDGLLDTVMDALLARSVIADDRKPNVIRVAPAPLYNSYEDCVNFVEALEEALRGASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJD9</accession>
    <name>A0ABR3YJD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phenylacetate 2-hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009859</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11066">
        <property type="entry name" value="CYP_PhacA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="57453" checksum="12F1A30794DE8457" modified="2025-10-08" version="1">MYATDIPYIKGLPEVPGAVPVFGHLLKLGDDHATVCEKWWRQYGHSVFQIKLGNTRAVVVNSFDDCKKMLLGHQNAVIDRPKLYTFHGLISSTQGFTIGSSPWDESCKRKRKAAGTALSRPALRNYYPMLDLESYCILRDMFRDSKNGEIEIDVRPYIQRFALNTTLTLCYGIRMDAVYDTLLREILTVGSAISLLRSASENYQDYVPFLRYFPNNEKNARSRDLRERRDKYLNLLLDKVREMIKCGTDKPCISAAILKDEETKLNGVEVSSICLSLVSGGFETIPGTLTSCIGSLSTPEGQAWQNRAYADIKRHYPDVRDAWKNCYIEEKIPYINAIIKEAGRFYTVSAMSLPRKTVTEVHWKGAVIPPETMILINAQAGNHDVDHFGPDGANFNPERWLSSLDPPTEATVDGGLPHLSFGTGSRSCSGQFIASRLLYSSLVRLLSSYKIVASDEAPPNTDYVDYNEIKTALVAIPRYFKVKLVPRDSAVLETCLAETEERTKAYYKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJW8</accession>
    <name>A0ABR3YJW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Peroxisome assembly protein (Peroxin-2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PEX2</name>
        <name evidence="17" type="ORF">Sste5346_009475</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF4">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="16">
        <location>
            <begin position="143"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="517"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="551"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="571"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1888606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="631" mass="68219" checksum="981D107A9F4CBF48" modified="2025-10-08" version="1">MTDRIPPPPPPQTAAAVAAANAAIAPSFAEAQRRLATRRSERAAAEAATRAQIAATEAARREAAAAALRARLDAGGPLASSSSPLVRRLGDTALIAWDGVSRAASTISNTLNSGNDSRNIDVAGTSGQRPAFRVSQVDAELLDEELLDLLRGQVADALKYIRGGTLQDDWQPEIMLLLRAALFKLSVWDHDATYGAALQNLKYADARATSGKRGAIAAAVPLPPSKWQKAAYGLVTVGGRYAWTKWEDWLRDHDEEADDGYGESNESNDNNSLSFLSGRLRLSLSSNAVKRLARVTNVASDLYAGAAFVSFLVFLRYGRYRTLLDRILRMRLVPPTSQVSREVSFEYLNRQLVWHAFTEFLLFLLPLVGINRWRRWLTRTWRKTKSAVAKATTAVKGSSDNEDDNGDVGKTGEYAFLPERTCAICYQDQNAATSEADIMAAAAASSGVIGSAETDITNPYEAVPCGCVYCYVSLATRIEREEGDGWTCLRCGAIVTSCRPWNGNVLEPASVLASAAGGATTADGRPSSSSTNASGSPSYTQKTVGFADDVKGEDEDEEDDEASNDEIQIGEIEDEEEIEDDVEEDDVEEDDGEDDGEDGEDSADVTDDESEAYEEDEDSIEGELDDDLEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKB6</accession>
    <name>A0ABR3YKB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009632</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000095">
        <property type="protein sequence ID" value="KAL1888307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="116"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="666" mass="70510" checksum="FC8C68F1A1CD0214" modified="2025-10-08" version="1">MFSGKESVRLPSTDDEGICSTSPTASTTTMITAAASTSSAVDQQQHTNQQHANPEQQQQQQQQQQQTQSEKNTVTVSDTQEANQMRDIEPMEIEADADHTGARREIKAPPMSSARFMALVGMAFLWTSAQIPVYFWGGIPPIVYGDLGGVDRWVWLITANLLASAAVCPFVGALSDLIGRRYVALLGCGFVVVGQLVCAFAHNMNSFIAGMAVSGVGAGINELTALAGTAEIAPTIQRGKYIGFLILTILPFCPAVLWANLIAANAGWRFVGVLTAVYAFAGLLVLAVFYHPPPRASASGFRSWRTEILPRIDIVGGILSIGGIVLLVAGLLWGGYQYAWTSAHVLAPLIIGIVLLIAFTFWQSRFAPYPMVPRRLVGHHHEGASGPPPRKRTMWLALIITFVSGANFFSVLMLWPSQAYNMYGHDPIGVGLRGLPFATSVLVGCIISLAILTRWRGGNRWLLFGASAVMTAGCGALAAASLDNLAAVYVILVIAGLGVGGIVVPASLVAMVICPEDLIATATAITLAVRVVGGAVGYCVYYNVFVHELVPRLEDELIGTVLKGLQAAAAASPTGSTGVSNVTALIGQVIMLTATSQTEAIAGLEGIGGPGSDFYHSIITAGQEAYAGAYPYVYYSSIGFGVVSMIASLFMDDIGMYMDDHISVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKM0</accession>
    <name>A0ABR3YKM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CDS1</name>
        <name evidence="19" type="ORF">Sste5346_009260</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1888876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="455" mass="51832" checksum="7690C382D439375B" modified="2025-10-08" version="1">MAKPRRGVRFPNRNGHDRRSSFSDASEDGQSPTKSRPAAVLSNISEKQTPEQEQAAEYEKKKQNFITRTFWTFVMIGGFFTALFMGHIYMIIIVTAVQIVSFSEVIAIANVPSKARQLSSTKSLNWYWLATTMYFLYGESVIYYFKHIVLVDKVLLPLATHHRFISFILYVFGFVFFVTSLNAGHYKFQFTQFAWTHMALYLIVVQAHFVMNNIFEGMIWFFLPASLVITNDIFAYICGITFGRTQLIKLSPKKTVEGFVGAWVMTVLFGFFFSDILMKSKYFICPVNDLGANIFTGLECDPNPVFLQRVYTLPHFFFLPASWPTFSITMAPLQIHTVIFSTFASLIAPFGGFFASGLKRTFKIKDFGHSIPGHGGITDRMDCQFIMGFFAYMYYHTFIATHKVTLGSVMELAITGLSPEEQVELVRGVSRYLRNQAIISEEVLACLDVALPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKR9</accession>
    <name>A0ABR3YKR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000084">
        <property type="protein sequence ID" value="KAL1888812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="117"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="211"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="647" mass="63124" checksum="19BC4B9869A0CEC9" modified="2025-10-08" version="1">MHLPRGDVGSGRPVYPRQNGGGFNGGGGGGFGGGGGPPGFGGGFGRGGFGRGGKGHGFPPFGGAGAGGGGGGGGGGGGGGGGGGGGSTANNACPQTNGTTIGSVQSFTLLCDSAVGGDVINSTTVDTFDACTVACASFHPKCEAVSFDGATCSLKANLANTGGGAATAAASTTLNGGIAQFPTASSNCGTLGASVTQSNMNFSLFCNNVVNGSDLTQNNAVTFQDCMDQCATTSGCGAVSFDASYAQGFKNCYLKTVGSTAPLVDTGIDTAVMNNAVVAADSSSAAAATTSVSSAAAVSSTTNAGVITVAPPQPSIVTQTVVSVVTSVSDSVSRTIVTTEVITVPMLSGSTLAGGGLYTSTATGTAAAATSAMSMAGMASSTATAAAASLVSTTDGGGNSRAWIAAPVVGSVAAVMVVAVMFVLWGRRRRNNGLSSPLSPAFLFNRFRGGGGDRGGNGGTNGFRNLSSADSNSQSFSRPHVPFGNSWTTGGKDAEKDDTTRGNNMTEKYSTGSGVARKIVDDEGGSSRTGTGYGKSVPLVINTGLARSSSSKSSKVKPNIVAVAVTTDAAERAVRDKGKEAASSSSGIGAASTTGSSSSEKPVPTRDLTASSSSQNDAKGKVALRDSLNGLAQNRTTLDGIPIFLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLQ2</accession>
    <name>A0ABR3YLQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="54"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="597" mass="64148" checksum="50A301A58C90FFD6" modified="2025-10-08" version="1">MADTGQRISYEKTETERIEQTETNRAPTLAETSADVDADDEGDVRPPGYWTSFRFLGSVVAIVLLANNLFIGYSMPASILSVIGKDLNAGTSISLASLTLTLIKGVCLLLVGSISDVIGRRYFLLGGQLVNFVGAIVAARATNVNMLIGASALVGLGQATQLLYPMLIQEIVPNKYRGISQGLLSLAIFPTIALGPAFARFMVANPKFGWRALYWLDAITVGISFILFALCYFPPGFKELQGGRTTRKSILKHIDYGGFILYAGGLVLLLLALSWGGSKHPWKSATIISMLVIGVLTLVAFALYEIYMPLHTPLLPMKLFKIKNFVVAVVVGSCGQMSWYALNLLWPYHIQNLYTTDNSKVGWMSCITGIALATGELIMGFFCRKGGRIRLQMIASVALYTTFSGIMAIANQHRESLAVGMITTIGFCVGWIELITIVVATLVVPPDQIGTGSAFFASTRATTGTIVSSIYLAIYNNRYPALMEPDITKAVEAAGLPESSLTQLFAAIANGTTAALNAVPGFTPAINAAVIDGRKSAYATALADVYLTSIAFGSIALITIFYGRNDIESKFTNFVNKTVSHVGGGKVEEDPEKVAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM36</accession>
    <name>A0ABR3YM36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peroxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ats1</name>
        <name evidence="4" type="ORF">Sste5346_009276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051016">
        <property type="entry name" value="Diverse_Substrate_AcTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545">
        <property type="entry name" value="DIAMINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF29">
        <property type="entry name" value="GH14572P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="183" mass="20262" checksum="2B05C72F0340E6C5" modified="2025-10-08" version="1">MASEEPIIRFARREDVPSILQLIRELADYEHAIDSVEATEEKLLSTIAFASETAGSIESAVAHTEPTSPSRPARCLVLFTPEGTPVGIALYFYNYSTWRARPGIYLEDLFVSSSQRKKGYGKKLLAALAKEVVAMGGGRLEWSVLKWNEPSIKFYESIGATMMNEWVGMRVDGEGLIKLAGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMZ5</accession>
    <name>A0ABR3YMZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009028</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="64789" checksum="5BCD2474E67C0043" modified="2025-10-08" version="1">MSSADIHPADAKTEATMEHHDASTSSDNVAAARRNVHTDSDSISINSAALGDDLPPGYFYSVGFLGTLIGFCLSAISAYMFVIMPTNILSYINQDIGPSDYTAWVNIARTLALSFTYTILGRLSDLFGRRWFFIGGNIVALIGIIISAVAQNFTTLIVGAAVYGLGETVQLSFNVAIGELVPNKYRPMVLSFVFLSNAPFASFGPIIARKFVATPSLGWRWCYYVNIINTGLAVIFLFIFYHPPNFELLHERKTKREIIKSLDYVGIFLWTAGLTIFLIGVSWGGSIYAWDSAATLSSLIIGIVLIIVLFVWEYFADLKYPAIPVHFFANRGFMALVACATVASMFYYSAVLLWPQQISHFFTKDITYGGWLSTTVASSTALGQICAGAIIRWGGNVRYWMIFSTFAMVGFVASLAALTPEKKDMGIALTILGPFFVGFIELTSLALAPLFCKAEDIGLASGLLASIRSAGGSVAVAVYSAILSNRLLTTIPANIGPAVEQAGLPASQVPALITAYKNNNITSYSSAVQAAVAAADPIAYTQAFKTVYLASLGFGGIAIIGCLFAKDAQKHLTDKVERKMQTVKTTKSAAGVTEKDASTVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN17</accession>
    <name>A0ABR3YN17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF35">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="38421" checksum="E13B72BF62D55F7C" modified="2025-10-08" version="1">MTSSVSLEMPPRTTGFGLLTLDSQFLYRAKYPPKSTNLNGQTGIITGASTGIGLESCHQFLGLGLSRLILAVRSQKKGDDTAAALRKAFPKARVDVWILEMESYKSVQAFAARVDAELPRIDITILNAGMLSNDFELSKETGHERVVQVNYLSTFLLTILLLPILKAKAKANGTSPARLTVVGSGAALASKHGWQDQRPLLPAFDDLNRIPWNFGERYWSSKLLGQLFFTKLYACVDPDDVILNLVDPGLVKNTSLQRGPSESSLLLAVAIYVVTNIAGRSVKSGASSYVDAAVMKGKESHGCFIMDWELRPFAKFIYSPKGKDCAEVLWKETMAELKFAGVEDILANLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNF5</accession>
    <name>A0ABR3YNF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045324770" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="50966" checksum="ECA276457D2EBD6A" modified="2025-10-08" version="1">MYLSRAFGITALVAALASPANAKACKPDVCSLVVQGKDGQSPGQIVQHQKDCSSFLSVTIIPATSTVYEVVSSIIGISSDTVGTLSSTQTDTITVSSTVTDVSIESGATTVDSTDTTTTTTTSTHTSTETFVSSSTWTSSTTTTTSITGTSSATDVLVSIASETDTSTTTATTTHTSTSTSTSYSFQTPAKRSVASEAGSSSAPISALATTISPSHIPDYATSACADSVSLYGSACAAWGIILQTTTLLTPITTVTQTVDVVDTIYVSGHTVVIVDITVTSTATVDSLKMSSMTVTDVSSATETDTLTSSATVTSTSIVPVEVISTKTQVSSTAITHTTTTTTTSTDTTSTTQTISRTVSSVVPWCTDLAVVRAQGCAASEWTLYCNQVVQPLGINRVVFNAPQQSLQECLNICDGNGFCTSGYFNGVTGACVLYLYAGSGYVQLVGTAGAVTAFEFIYGTNQGGYECPAYECPENDQPQCCGGMGCPDYLPPDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNL6</accession>
    <name>A0ABR3YNL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vegetative cell wall protein gp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1888994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="56378" checksum="54D20A8DF123BAC1" modified="2025-10-08" version="1">MNASYSPYASTPAADYYYDKKEYVSPSPTPSPRGPTYYYGSQPQRPATRAHFRHMSSGGVAGLAADRSVGGGGVFHEYAGNTSSSRPPTFSPRYTSDGHYATANVSSSRSAQKKSATTTTTTWATSSPRTPRRERRSASFSYYRTSDSIGDSDEDELIKIDGVTYVLPPRSRTRKQPQQQRSQSYYIRSSDKHYPEQYYHGGKHHRDDHYSSSRNYYYDDVVYGTNHIHHLEQGGYGFVEKDIGRGFESPRFTDATEARRTTPTGSSGGHGHTRRASTSMPMPARPQTARPSSSHYHPPTNASSARKSSAAAPTSTPPPPRATEADAKKYRIPAGYSLKNWDPSEEPIMLLGSVFDANSLGKWIYDWTTYHHGSTSPISEVAGELWLLLIQLAGKIRRTDEVMPRVRTKENREMLEDFIISGERLTDKLRKLLKTCEAPMLRTTGKRDKSQLGKNAGIEFVETLFGHDREMEKTERFMQSVRLWNLRFDANCEDILRKPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNN6</accession>
    <name>A0ABR3YNN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008713</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="21"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="443" mass="48738" checksum="57EA5F1B0DB6C470" modified="2025-10-08" version="1">MTATKSHGAATTANGAHPSKSVVIVGAGPVGMFLALKLGKAGINVTVVERNVEFSDAPRACGYYAASALAMHAAGVWDQIRDEGFVIKGLCWRKKPVDDGEGKGSKKLGSMIAAQPLSELDDDAMPPGTGILCLQQSLLTRLFAREALATKHVTLLFSRELMAIEEGESSTTAVTRDTATGGMHRITADFLVGTDGGRSMTRKLLRIPFPGHTWPERLLATNVTVHNTEDPVYHCYYLLDPSNFTVITPLTDPVLGQESLWRYTMAIDPSDPRTDEELLRDETVGKLYEQVMPGPRPLQYTIGARSVYRIHQRLASTFRRGRSLLAGDAAHLCNPFGALGLNTGILDAEALTEALVMVLHEGRPLAVLDTYSDERRKVFQFFVDPTSTQNKIRVQSNHEDEAVTNDWYFRLLQNPTADVLRAQAQPYFDVWRTDLRKAAENVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP88</accession>
    <name>A0ABR3YP88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hym1p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HYM1</name>
        <name evidence="2" type="ORF">Sste5346_009062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="384" mass="43973" checksum="4C774E0C4DB31586" modified="2025-10-08" version="1">MSFFFNRGRNRTNAAELARQTYDLLARLDVANNPNPKIDEALPKCLSQMKTILQGTPEAESSPEQVYQLVHGIVDEQVLCLLPQILHLLPFESRKDAQVIFSFVFRYRPPSNYPVASDPQNNQQPPPLAVDFVSNHAPSVLISLCHGYDHKESATTAGSILREVLKHEAAAAVVLYDDADDDPSSGSSSGGVQKIAFNRVQSGRGIFWQFFKWIDTSSFEVAADAFNTFRELLTRHKELVPRYLSINFDLFFGRYNTTLVQSNSYVTKRQSIKLLGEVLLDRSNYTVMTRYVDSGEHLKICMNLLRDDRKMVQYEGFHVFKVFVANPHKSVAVQKILIMNRDKLLTFLSHFLEERTEDEQFIDEREFLIKQIRNMPPKPVPPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP96</accession>
    <name>A0ABR3YP96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1488"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1557"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="797"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="948"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="969"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1232"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1293"/>
            <end position="1303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1583" mass="168498" checksum="36112BF9D9DA7E7E" modified="2025-10-08" version="1">MSLRWTPPGIDGFDRPTSWHPGFFNQPPDNGNDTNSASAGPKTAASLQLENDENGSPAPIRIMSGFSASQQQHPDRERQRDWSGRRAAPPPLPLHERSASESNRLTDIRIVPYTPPRLDSAQQEAQSAQGQHFSGPLSGPTSGPPSRSSSSSPRRRRRQRQRRRRSKDRDGNNGSDSNGGEDSDQTTTTTTSRRISRPTSWASRGSWGPSSVFAGATSARAASPSASTSGSPAPGSPGSKASSSRTVVSGKSGKTGRTGGKASVLVEKSRNSVIGTKWANATRSGNGNGNDGKPPLDKEGYAFSGPGSALSTPVETVFPLARGGRRGVSGSKLASPTGSQFTTATTTTIPSATSDTQNTNNATSRLLAHNPRHQPQQQQQQQHQQQQIRSHDFDLEERLHDLHNERNEPPSSVRSAAGPQLGLTPASASFSAAAASYLTEHRSASGAPQLQLPVSPSSPIAFPTSPSSSSTFFLSSSYHQPLSITTSNTASSTITGPSLSPSPSVASLTSTSSSQAAPRPNSRRRNLVALHADKTFSLVPRNVHRSNSGKKRGASSGTAVTSTSAISATSPSGLFVRPDQPPLTSAATTISSLKSPPLSFVTSTVRSSSSHERLSSDVFSGDDHPSSPLTTTSATLQDRTSLSPFTPSPGSSTVQLHHLHDLHEDPIPDPSLFPPPAVPTTAGVSSSNNTSPWNYRLAGGLRKVPKTPDFKRKGKGRAVPSTSVETSTSYSPYSQKHHPVVSGLDVSILPPLSESTSSPTTTIIAAGGASAIGSSTRVASNSTYNTETTLRPQRKTSFASDQSAGSSLSFSASTISAATNYKVYAHSSSPAGAASTSIALESTDSFDLPPSSSHSTNIEILGVSSPAAPPLPALQRSDDPDQTFASLVSYPSIASFDTGISESSAPNFVVLGASSPPAPSRYLDRIRNDFTPDVDIPSSPPLPPRSATTTTGTIDTSDTDPNYVLHGEPSTISFPPQSSSSNASSLVTISRQPRPAYSQESLIVPPLKTVKAKRSNERFGYYKSRSRESLRRAASIKSISSLFGQEAASTFFAGQAFLNIDIPPIPVFTGSKAAAVLKQQGQLPGLVTKKSLPKVKRKPLPLPAPPVKKSENYVVYDRTPNKKTGPPASSDSWDSPSSSQLTSSPHSPTLPQQPLSKHYAKATVQMVEEHPHQWSSQLSTVMSESEADSIRVVSRPVSVVSGAPSGSYIRGDVSAISGASARRSSAGWASSTHSRNMPSISSSLGLQMDELRDRNSRSDSLLLDRPNPAYFRTNSASPATSGSAAPPPPPIRTVRDHDEHGDGLADLQDIGRQPSRSGLSGFFSSSNNSARNLHSSGSMRSIASGGFPSWARVYYGSGEHRALSVEPSMSDLGQGDDYMAGIGRPNSAFRRSPSMDNMHFNIFNTRRRPREVQPAGPRPFSDAASMEAGEAGVMHDYRLRPPGLRKMTSSIWSPHLRVDRRATRFSVWEPPSVTWSTDTSSAFDRRNLQVMCFTFGFIFPFAWMIAAFLPLPLDPKRAMEKRAEGEYGVPEALKRRIAQYDEMRFQSAKWWRTLNRVMSVFGLLILGAVAALVVVGVRQGWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPC8</accession>
    <name>A0ABR3YPC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="120"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="303" mass="33397" checksum="A09E54B4502C962E" modified="2025-10-08" version="1">MPNRAKEGYLSLRRKIRGAGAGAGAGAVNGSGDGAGAGEGTAQPELTPVQKDLALTFDVFALPKLFTPIDTTITPSELFPSGVIVVNGINEVAERQFYRFVYRLDPQAILIYTAGRIATRQSSGMSWTRGGCGHVYHGEVEASNHGDRRFENADRPHERRVLTMQLEEMGADGKGHKVTIGRAALRAALAVLQIREWTANGIKRLVIATDSEYVVKHATQSLGKWAPRNFQTGQDHDMIEDGDLWKKFWAECQFWYEQGLEIFFWHILEEQNSLARSKAVIGAQMPAVEEFGGPKSLAIQKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPL1</accession>
    <name>A0ABR3YPL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577669" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7547" checksum="8717DB1C74EB5758" modified="2025-10-08" version="1">MAVAGLRGRRLNITMSVLAALVFMMQGFDQALVNSLLTVHTWVKTFPGIDTVNKTGARKEHNSKIQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ69</accession>
    <name>A0ABR3YQ69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="1">6.3.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Diphthamide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diphthamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphthine-[translation elongation factor 2] + NH4(+) + ATP = diphthamide-[translation elongation factor 2] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10174"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16692"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.14"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="AANH_PF0828-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06156">
        <property type="entry name" value="eu_AANH_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1490.10">
        <property type="entry name" value="putative n-type atp pyrophosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthamide synthase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="598"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="724"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="730"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="832" mass="89837" checksum="70D2BE04CB7805E1" modified="2025-10-08" version="1">MSLNVIALISGGKDSFFSLLHCMAHGHNVVALANLHPETIDAKDDEDEEDLNSFMYQTVGHQVLPLYAAATGLPLYRQPILGHAVQSGREYHHGSEEGDETESMTRLLRRVMADHPEANAVCAGALLSTYQRTRVESVAVRLGLVSLAYLWKYPILPASISSYISSAGASMSTITDYLDDLTAAGFDARIIKVASGGLDDSLLWTNVATAAGRARLQRALQRLGLADDGPGSMLGEGGEYETLVVDGPRALFRDGSLSVDDADKRVVHEGGGTSWLRIKTATVVPNEKTEGVDDRRVEVRQPRMLDARFSAVLELLKEASADTTEPLAASLSLTDETPFTLTSTQPSAVTTWRVVPELSSTSSSPSIADATQSVVDQVRQRLQYLPNNLSPTHSVVRTLVVLRRMADFPAFNAVYGTLFTGAPNPPSRVTIACGEELPEGVDVAVFLSVLDDTTKTNAAHRQGLHVQSRSYWAPANIGPYSQAVSVLAHGDGNNSSSGPRVVSIAGQIPLVPATMELSDQVVEAREGGENVQPSSSPASFSFHATLALQHLWRIGIDLDVQWWGSTVAYVPRQTDEAALPSLSTSALLAAQAWRTAHEWRPKSEYDEEDDDEEDSDGPDLWDRKFDARFAMYGAIGGGDENTPQLPDWRVLDNSSPAKSGSAVPPVFLAEVQELPRSAPVEWHAQAGFSHVSTGGNSSIQVRAWTGTDNSSNKTWTYQTILKTAPPRDDNYDDITDSDDDTKDSRPAPPPRSSRVVIQTTTAWAYPADTKATVTLSDAALAQNVDMVYADMHVCRVPDTFVGTTPVVPCASLWNGRGERLAAVVVQTIHGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRJ8</accession>
    <name>A0ABR3YRJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="18"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="336"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="548"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="629"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="571"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="661"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="688" mass="74581" checksum="F1DC1B4072BEFCC9" modified="2025-10-08" version="1">MNDDLATMQLSEQQASVVVGLERAGASLSMIGVFLIIVTFALFKRLRTVPNTFILFASMANIGAGTASLIGLLGIAQGSNSTLCRAQAFLLEMFMQSDPMWSFAMAFNVYLVFFHSANPTTFRRHLWAYCLACFGLPMIPAIVCLYVQNADKGPVYGDATLWCWIDDSWNALRIYSYYMPIWVCIFLSAVIYVAVGYHVFHQRNQLRNLTLSNQAKDLSSSENLTRQPEIYGTVTTEVQITSDVCETALSSERTPPMTPLGSPMQCPWSDDPFPQTIDNSTNSAFINHHMHHLDEERGLGSSMVSPPPAVHGGIHGSSSHGIHSGPSTVYQATSTTVITSPSPPHGFQPVSSHHSSRSNDHLASTYRLQPQLSSSHGHSHGHRSHGHVAHSHHLRGNSNRGGRNSNQRISVAEKFRRAWHRFTGKLRHMDPVKLAYLRTSFVFAISVLVTWTPSSINRVYTLVYPSRSSYGLNIASAAVLPLQGVWNAVIYFSTSWSLLQDEVGRRYQRSRWMRRVGGQIHGGLARLRGGNGDKEAAGSSGRIPGIVVAGAGEDGSSGGGAQMGTVLSPARSHSYSQSHPGSSSRRMSEVSPGGIGSMSAVAVSHGCYDENDTESDGLDGLDGLEGFNEHASTIGSSSPGLRAAGGHRRLRPAASMDLDAGPLGRGQRSPRSPPRGTLRVQRGGQLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRX8</accession>
    <name>A0ABR3YRX8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="168" mass="18526" checksum="0DF142051EB65724" modified="2025-10-08" version="1">MYLNKLTDTTKFIGLTANCYPRPHVQSMIFATDSVGMAVLLDPEHATTGVDDKYGASNDTVGLSGCYSSHRAAVHSEIGLATLIQNAGYSVDVMMAAFHQETSLEAYCNATDNKGDVLNNDDYFGLNLHPYETIFFKTNRKIDPVAIKMLTEWHLKRNVTAQTLCPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSF3</accession>
    <name>A0ABR3YSF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="308" mass="34116" checksum="3F19F855654D31C0" modified="2025-10-08" version="1">MATDLDKHDLEQVDTVATGPFRTAPQWIRDVTPDELAKRETHLRRKIDLRLLPMIVLMYILNYLDRNNIAAAKLAGILEDLHLSATQFNTTVSILFAGYLFMQIPSNMILNKLGKPSIYLPSCMLVWGLISGLTAAAQSYGGLLAARFILGFVEAAYFPGCLYLLSCWYTRKELAFRTGLLYSGSLLSGAFGGLLAAAITGGMNGVRGLSAWRWLFIIEGMATVVVAVAAAFIIPDLPRTTRWLNEEEKQLAAWRLEADIGEDDWVDTKHQHPLHGFKLAVLDIKSWLILLVIYGSTASGSMTTFFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSS1</accession>
    <name>A0ABR3YSS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="120"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="418" mass="44650" checksum="D62F081FB92F8164" modified="2025-10-08" version="1">MTSTNPKVAIVGAGLTGLLAAHGLKKNGFDVAIFDGEAHIDARPRDWTIVLHWALPVMQALLPDDVAAKLPRAICNPNLEFDANAESFPVYNGVTGDLMFASPMPGSRRISRQRLRSVLAEGLDIQWGKKLQSITTATSSEGDSSTPALALAFEDGSTVAADFVLGADGAHSLVRGVVVNDADKARSTPSGLLFATAIVNYGDAAKVKTVTDTHPVAAAAMGTDAVGGCGVLYVNDGSDGAPARDIADWTTFWVKIWQGHLDKAVQGQEAIDLLKNSESSKKLAAPFNQQIEWTPEGSVCYIDEMKYWVPVPFAGAEATQDARVTLAGDAFHPMLIYRGQGFQHAITDVDNYIKALVAVREANWDADVRRREIGAYDAEVVERGAKAVTQSAQEAALSFDVEKVSKMLMARKGHGRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSV1</accession>
    <name>A0ABR3YSV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH-dependent flavin oxidoreductase</fullName>
            <ecNumber evidence="3">1.3.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">OYE32</name>
        <name evidence="3" type="ORF">Sste5346_007963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.42" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016629">
        <property type="term" value="F:12-oxophytodienoate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF2">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE PYRROLE 2,3-DIOXYGENASE (AFU_ORTHOLOGUE AFUA_5G01450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="50"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="429" mass="47000" checksum="8D9AF2F2F7846B20" modified="2025-10-08" version="1">MSRPTGTTQRGRKTASLPAPGVPFYTPAHTPSTGTATQSTTHDGKPIPTLFTPHKIRGVEFGNRFVVSPMCMYSADDGHLTDFHLVHLGQFALNGAALTIVEATSVTPNGRISPEDSGLWQDSQIAPLKRVADFVHSQGNKIGIQLAHAGRKASTLAPWHVAKRGEHQFAKESEGGWPDNTWSASNIPYAPDWVNPLEMTLDDIKELKDSFVAAAKRAIAAGIDVIEIHGAHGYLMTQFLSPTTNKRTDQYGGSFENRTRLLLEITKEVRAVIPESTPLFLRLSATEWLESANEPSWTVQDTIKLADLLPSLGVDLLDVSSGGNSREQVIKMHSHYQIDLVSQIKKGLREQGSKAAETLQFGAVGMISTAELASEVAQKGGPVEADLVFVARQFLKEPEFVRRVAHNLGVPVRWPNQYHRAQWKPDAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT34</accession>
    <name>A0ABR3YT34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="180" mass="19519" checksum="DF585BFAA194CC7B" modified="2025-10-08" version="1">MLSPHPELRGTRPAKDKYRRPALSSSQPDLEALSDLDPESDSETIKGANDDTVKIDSTDNTVSTVSSVSNGTKSSVDTKGSVEDLTTSLGTLTVIEKTVDKIEFAREQTPEVFVFNSPQTTPVAKKTVETKGKAPEPISKVELPIRTKEDEKSTETQDKALLAASKEDNKPNEKVTDEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTA0</accession>
    <name>A0ABR3YTA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007524</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF5">
        <property type="entry name" value="DUF907 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G06100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045517118" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="28"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="617"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="29"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="767"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="833"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="853"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="919" mass="97935" checksum="DB5FF397F10B9E16" modified="2025-10-08" version="1">MARNRPTGLRRLALAASIFFQAATISATDILQTTGFNNCGGNDTTVTVQKVDIQYNNANQTVTFDVAGTSAKVQNVTAILNVTAYGTQVYSNSFNPCSASTFVKQLCPVPAGSFAASGSQAIPAEFANQVPAIAFQIPDIAAQATLQLMAMDGDNKGQDVACIQSQVSNGKTTDIPAVSYVAAGVAAAALVLSGVGAVGAAIASGSSAAAAGGSSVAGGMGTISPSFGEVFGWFQGMAMNSMLSVNYPQVYRSFAKNFGFSTGLIPWTDLQIAIDNFRVATGGNLTNDSVQFLQNATLVFPDGSTETPSQSSLSFRLARSLLVSPEVHLLDRRTHALLLREITTSINGTSSAGTNGTDSTGGTVSTVRVAVSGIRAYVEQLSIPSASTFMTVLLIVSIVIAAITVGILLVKVILEAWALIGRFPESLSGFRKHYWRSIARAITTLILLLYGVWVLYCMFQFTQGDSWAAKVLAGVTLGLFTGVLAFFSFRIWYTAQKLTDEEGDASGLYDDKKIWTKYSLFYESYRRQYWWVFVPAIFYMFAKGVALAVGDGHGMAQTIAQLAIESVMLILLLWSRPYERRSGNVVNILIQVVRVLSVICILVFVEEFGIAETTQTVAGVVLIAVQSALSGILAILIAFNAIVACVKENPHRKRRKELEKARDTDNLTPLDARNSLLQVGQVNKRLSGRMSPIDEETASLSSVPDKKVDMAAVPSTNTTNTAALVPAATSTNLAVPRFPPARQASTVSSTLSASSGAVLIGLASSAPDARSLTPSNSNTGAPNFSSRLQYSGSRRIADQGGESLLGDMAPMGRSDTADMRQPTLPNLGGGGNNMNNGPRGPPTRNQTYGGQGYRPRYNYGNGNGPNYQRRSNSYSPFPPQQQQQQPQYMAYNGNQNNYGNFNGNFNGGYGPYRGPPRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVW0</accession>
    <name>A0ABR3YVW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ GRASP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007036</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="117"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="253"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="375" mass="39473" checksum="4CD74973E0B3452C" modified="2025-10-08" version="1">MFNALNRFISRLDGEGPATDKEATHGTFGFQVLRNTNLELTVEPWFDFIVGINGRMIDDSDPMLFAQEVRNCAGGTVTLGLWSAKGQRTRTMHVPVPYDTAALGLSLQWTPLAVVSNIWHVLDVPARSPAELAGLLPYSDYILGTPEGVLHGESGLGELVEDHIGRPLRLWVYNNEYDVTREVSIQPSRDWGGEGALGCVLGYGALHRLPAPLSEPVSGPGETMFDGDNEKTHLHAAHGGPIAAGDMFEQAATTPTAPTFPGSASGAHPPAGGAPPAADNFLVPAQLVSPPPPPASGAGGPPTSGTATRSKKKDRHHNTGGNAAGLSVDDYFKEEEEKSQQLDGAPSRSITPVAPPPKGGPPRAGTPKEAAKEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWX9</accession>
    <name>A0ABR3YWX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="58779" checksum="DB4554FC8E641175" modified="2025-10-08" version="1">MAFDNLPPLISPTVLVTAAASLLLYFLFSLLRRSQHSALPLPPGPPGRFLVGNLGDVSADHPEEDYMRWGKEYNSDVIHVKVLGQHMICLNSVAAATEILDRRGANYCDRPRFALFEVMGWGLTLTFLRWGQQFKLHRSLFQKTFTASNVKVFRPIQLHEARKAVVDLLEQPDKWEEATLLMTTSIIFRIAFGQEITDVSSPYCEMAAAANEATTNGGIAGTSLIDLFPPARFLPDWINPSPALRHARNSRKAIQTIHDVPWAASLKDIEAGTAPPSFMRTHYERLQESIRSGKPIEMTERDIKGATGAVFIAGGNSTWSTVLSNLMFLAKNPAVQKRILEEIDSVLGVSADDPSSTPRLPTFEDRPNLPRLDRFLQEVQRSLPLNPLVIPHKSLKEDEYRGMRIPAGSLVLANTKAMAADPHVYQDPHIFDPDRYISTDEGGRGESFPNGNFGFGRRKCPGNFLAMATVYMFLATLLSVYEVEMVIGPDGKPIEPQPAVTIGLGGHPAPFQCQLRLRNPAMAQLLKESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXE7</accession>
    <name>A0ABR3YXE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="180"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="37572" checksum="A9DF8894F0FCC003" modified="2025-10-08" version="1">MAATIPIIDFSGFYSSDPATKQAVVDQIREQCGINGFFQITGHRVDAALQDNVLHWSKMFFALPDEAKQACSKENNTWNRGYEMLRSQILEEGTQPELKEGFYIGADIPTDHPYFINKKLNSGPNQWPKDGFTAGALEGFKASTMDYYNATVSLAGDVLQALALSLSLEESFFSQFMDGAVATMRLLHYPIQPPDSDAKLTRGIGAHTDFGAITLLLQDDVDGLQVWDKNTSTWVDVEPVKGAYVVNLGNLMQRWTNEKYISNVHRVINRSGKERFSIPIFISGNPDYVVECMPNCKAPGEPSKFPPTTVEAAVSSGYAESYGRAQRFKQGLERAVAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYN3</accession>
    <name>A0ABR3YYN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_006672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF229">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="57991" checksum="6F455E9407518E1A" modified="2025-10-08" version="1">MLDSSLLHIPRPSVAGLFGYLAALLVVYWAAWVVYARFFHPLAKYPGPFWASVSRFWMVGQIRKAESEKTQRKLHNQLGKIIRIAPNEVAISDPEAIKIIYGINSGFTKTDFYTTWRPAWCKYPDAFSNLDEKLHASRRKITNNLYSMSSIARSEDSIDFCTAVLMEKMAAFANSGETLDMAAWSQMYAFDVVGQLFFSRMFGFLEAGHDHRGYIKALDLLLPILCAASVMPTYLRTPFLMGGALVQPRVLKALTSLTDIDNAAAECITEREALLAKNANEPSDILSSLFSTMREKGEKVDFGLTEVKVEVYVALFAGSDTTAAAVSSILYHLMKNREAYDRLTRDIDEATASGELSTPFIRYKEASSLKYLDACIKEGMRLHPSVGLTLPRHVPAGGCQIAGQWFPGGVRVGVNAAVVHRDQTIFGADADEFVPERWFWPEAANMERYMFQFGGGARTCIGKNISLCEMYKMIPQLLREYKLELVEPQRSWKTHNYWFNKPSEVYTRVTARNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYY6</accession>
    <name>A0ABR3YYY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="30375" checksum="A2015A9E1E5D9105" modified="2025-10-08" version="1">MDGETSSALYVDDLDGSNEDASAASGASSSGTLKGKELERDPEASDPVVATSSTTLSSRSDTPASTVPDSTTGPAQQNNTGPAQRNNAATQAPKCPAEQVLAFFKTVKDITRIMISDPEAPSQDIMGTIYGRHPTCQSKVAVALPGRGGEPRTLRGYWVDCSDLKVSWKLTQYKILGHNYVFPRATKADLMASRKRNLILVLSMPWGSTFHISGLFILDGTLALVSGSVMIQVWGKLATNERLLDHTKMAGQTDLNGLGLKRTRDRAQRGPPLPEPFNFQPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZJ2</accession>
    <name>A0ABR3YZJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine repeat protein-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="585"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="65970" checksum="23D5BFEE9B6632A7" modified="2025-10-08" version="1">MQQPGQQPPPQQQMPPGSMPGQQQQMMYAQQFGMPGGQSPFMQGGGNPNMMGTPGPGGMMPSPGMPHMAANGQMGYQAPFTGSPYGVGMPASAGQPQMSPNFNMMAVAGQMPGFPMTPQQQQAFMQQQQQQQQQQQQQQQRMQPPQQGPGGMGTPQRPFNPMQQGSPMAGMPMSQQQQIQQQQQHQIQLQQQLQQQQHKQQQQQHQQQQQHQLQHPQQHPQHPQHPQHQHQQQHPQQHPQHMQQQQHPQHPQHVQTPQQQPQQPPTPSPKQLQHQQMPPHQSPHPQQMQPPPPQQSPHPQQQQQQQPPFNNPMQSPHGPPNAPQHPNAPQPPHSAGLQAGASTPQTPTFPGTGGPVANGTGAAQGPPLSPGSESREKELFTVLLNINQELLYESIQLRSTQIALKKEHAAEAGVEEQQPSETTEPVSEEEKLVRADYIQCMKRIQSNLAYLASLADRKMTANAAKGPSFLSAPPLSLNFRLRAAPPPPPPAGADPSQIPEHQDPNSDREERFKYIRELYGKLQSFYPGIDYTREPAFAAQPSQSNQPNQAAGGPGGPGGPGGPFNNRAGPGGMPNQGSPPMHRTPQMGMMQGPPGAPQGIPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY4</accession>
    <name>A0ABR3YZY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_006050</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF5">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185400" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="10">
        <location>
            <begin position="22"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="11">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="186"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="187"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="296" mass="30700" checksum="B53F495E194B6C02" modified="2025-10-08" version="1">MRFSTILSVTASLAMAGVARAAHGDGDEGSIMGPVAFLWPDDRSWSAAADNQGPCGSSDGVVNRTSYPLSQGSVALSIADEAYKVAFYVAFTNDPTSQTEFQEQVVNNVTEVLPGHQCYKIDPIPSSIKAGTNATIQLQYWAVYEGENNNQNETFYACADITFVEDEDFTGSVPCFNVTAADFNSEGSSSTTAAGSAATTATNTGSGNSAATTTASSDSSGSSSDNTTEKKSGGLSAGAKAGIAVGSIAGAGALLAIGFFIYARKRRTGYLERRRASKINAPIPLNKRNPESITSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0J3</accession>
    <name>A0ABR3Z0J3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="3">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="242"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="502"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="697" mass="78085" checksum="E263FAEC3382F887" modified="2025-10-08" version="1">MLSDRDRGIELARLSSARFRRLRSGEPSPPIVTAQESAMAVVMEHLTDKPTWFEDIFDDAVIVQWRNEITESDLVANPRLLQGTTWPWIVRELRDKAADYKDRGYSSGKESSPYLTSTNTTNNDESSESSEGSTNHRLKHGEIEVADVPPFTEYLEIVQTEATAGVHGEAQADTQTNVQAEVLAEIEAETEDGMFGNLDDFYSDSGEPTPANVVLDRLTAHWDMPTEDEDGQPLVLGPRLAESEYRIAALVDPRLYPLVNGRTQYLSDGNTVALDNVLTSYGANSSALETCQSKQERHQYLPLPCEVAFTGQDTKTTVGVQITSYINNLYPDHKNLYRAIEQECEFHDVIGKEQLSLPPLNSDVWQKANEYLQDYGGGDGKDGINNDDDEDMWGRLCDKTCQRVIHRHPEPGLYDDWKEAMLAHEEKAIDPVQQFQEQGLQVLVAINSIALTPDGPAYGPGATTWQAIYARKTKEAFAEAVTQNKAVCQFGKPPDSDGWSRVEDNIVATAMVAFDVTNVTTPHLAFQQSQSDITEYSYDEAYKYDWHNVPPHLVGKDNDKDALAEVLRMPVSDLWNEGYGVYDFQDIGTVAMREGRVVAFPAALGHRINPFCLVDANQPGHVRWLTLSLVDPGAHGRTVSTRTVPPQQHDWWATAVRRELTSIGGLSNEIIDWILEDTDKWPMGQDEAEWHRDRTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1V9</accession>
    <name>A0ABR3Z1V9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="75" mass="8618" checksum="5D90370B252C5F02" modified="2025-10-08" version="1">MPLSTHRASPSSLTPMTRGFVCMPEEFKATIRPRSVARKKKIIEEWETAAKENLDPVTKQWLSAVMDKDMWKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C6</accession>
    <name>A0ABR3Z2C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF8">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="31354" checksum="1FAC8CB6835A72BF" modified="2025-10-08" version="1">MAAPIMAGYLATPLGQVHYYYSAPVTPPSSPKPPMLLMHMSASSAKSFLKMMPMLTALGYTCYAPDMPGFGNSFDPEEDPPSISWYASLYYEAFTSQVPEFKDGVHVIGHHSGGILGMEFASNPDQYPGFVRSLTIVGASVMTVADRAKMSKTFLSPFNKPVASGEHLQKTWDYLKWEGLNPDVELELVHREALDHARAWKGRNQIYSCVWKYERMEALDAIPAEVKVAGLCAPDDVLWPYYGNFKALVTRPIETTVIKGGNFGPDLDPEGILYAFLRLIGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2J9</accession>
    <name>A0ABR3Z2J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">INH1</name>
        <name evidence="6" type="ORF">Sste5346_005933</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="96" mass="10874" checksum="1F568AC2B98F0CEF" modified="2025-10-08" version="1">MLRQFTAVARPATLRTATRTFATSAIRMAEGDTGAPRGTSDAFTKREKAAEDYAIRQREKEKLMQLKQKLKEQQAHLEQLSQHIDELTKDQGGEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2N3</accession>
    <name>A0ABR3Z2N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045084313" description="Cell wall protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="20201" checksum="2A2781F367A6F655" modified="2025-10-08" version="1">MLFNAFTSAALLAGSAFAAAVPAATSTGNDTADAIDFVVDAPLAVTLGSFLSLIDTISSVPDSVIDAGDDAVHAWLAPIGAPAASAIAAPNSLIEVRSTEATNAADTTAVAAATEAVNGIIKDLECAAAVAAAIASDVLPAAKILKAKKLIKVLGGVKKVAKLFLEFHKNRDEAIKEGGKTLLELVEVLLGIDSIKKHCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3B5</accession>
    <name>A0ABR3Z3B5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PITH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PITHD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045099">
        <property type="entry name" value="PITH1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175">
        <property type="entry name" value="AD039 HT014 THIOREDOXIN FAMILY TRP26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175:SF1">
        <property type="entry name" value="PITH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="3">
        <location>
            <begin position="31"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="236" mass="26169" checksum="10919A55183793F2" modified="2025-10-08" version="1">MSHHCHDEHTGGGGHDHHGHGHGHDHDHDHSDDVTPALQFSLYQHVDFAQVVTLNEAESGSGRAIVQKTWDQRLEDEPELASDVDEQLLMHVPFTGQVKLHSILLRTSTSSDAPRTLHVFQNRDDLDFGSAEEEADAKHATQTFELAQTSDIQEFSVKRAIFGQVRRLTLFFPDNFSDGEQDVTRLSYLGFRGEWMQLGRAPVNILYESAANPADHALKGTSVNQMGSNIGGGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3U5</accession>
    <name>A0ABR3Z3U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Synaptobrevin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005619</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the USE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019150">
        <property type="entry name" value="Vesicle_transport_protein_Use1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050">
        <property type="entry name" value="USE1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050:SF7">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN USE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09753">
        <property type="entry name" value="Use1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="129"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41482" checksum="835FB1BB9DE5E58A" modified="2025-10-08" version="1">MGRPDPIPPYSASPVPSFSSFSSSTSISYDPFVDLGRLLARLEQNLLRADSDRWRRLVADEFQRLQARFDVAAARKLLTRVEQSALSIKVLSQRQEVQAELNRRRALVELLQERLDNLDEEARAAAALHGGVEDADNSEGEGEGEDDDTTHIIRAPSAPHLSVATQPPAALATDLPTPTSTTDAPTPTSTSTNQPSKPRRKKTNRVRIAAPEDQATTTSPATTTTMTTRSRRKQQEVEADDAASIQTQDTARTTATSLFEKSGDGESSGVATEEAVLDHHRREQEALSEDILRLAKALKEKSLVTSRMLEDDKDVVDRVGEGMNTTTDSLSAASRSMAILTRMTEGKGWWGRMLLLGMVYGSMLALLLLFLFLPKLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z406</accession>
    <name>A0ABR3Z406_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="815" mass="90395" checksum="17AF7A72E580C75B" modified="2025-10-08" version="1">MDSPTYQEPDQELDQQLEQELFGSDTEEATPAKSKANNTHTPFLPLPTPMPMFMPMPAMPALPATPAKVVSARASQKAYPTRSCSAASIPDFDGDQKRQLWKMVKATQRRGSKTTDPKQLLQRFLDRQHAAPVPQPPYTAPVPVAPVTHLQHNIPISTQQQPKANPPPPGAKISHARDKNSENRIGQYDWYDEFPTRSNWTARVGDCQVQVKYSKQGELKPIVKFDRKILEAYVRGCEQHGIPLRLWIQNSATMHTDRFPSRASSMCRATNCPVRNNTIARGMYQVCFDEHPTETSNGRFDPFYVAGYMHLFCLEEMIPMAELMTCADVQPDTRDFPLEQRNPMSLNRDGAGRTLLGAYNEWKSAHYDRYVYNDISIPKATRRSSDCLYKFLTVKKMEAQPSTRQKMRDQRNGFDISKHCGNLRKLVTHKADAKKKRKQARSDSSEDGDADSDLEVVLPPRASAPKRVRTEAANVAAASAYPPLQSPLRRSRRLSGAYAAQHINMPAQTMAAAPVPTSQIPYMPYDMRYDLGTMAVPSMSGSPPRSVRAASIGLNVRTDLTLPTAPTNILDFNTANLDVDSDSFWNVYNDIYSKDQQVLPLTGLPPLASYGASPSSPYKLRDTQARRQSAVRLVSARASQVTHSLSSAGLINPLTAGLIDPRLLQGQGSTSHHSPKYPSRLHSSTSAAAAAEEVLTPTRRVTRSMSRHHTGNTPVEQQNSHAQFEKKPKTPAAIQEELAVDQAAEVAADADANANTTTTFDFTSFDASTGMLEEGAFDNIDYTALLEELGNQNDSELLLPDGFYDTMQMPLSANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z487</accession>
    <name>A0ABR3Z487_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1750"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1854"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="736"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="801"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="875"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="903"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1069"/>
        </location>
    </feature>
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        <location>
            <begin position="1272"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1316"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1363"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1412"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1458"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1520"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1668"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1691"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1703"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1716"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1727"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1751"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1780"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1816"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1858"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1883"/>
            <end position="1897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1956" mass="205294" checksum="13C03D8783B221C9" modified="2025-10-08" version="1">MFGSRKKGNKKYTPPTASSVNPSAATAAVSAYNLSSAAAATALRNLPAAPTNVGAVQTKRTMRRSASVSSEGSRRALSPVPSIKRAMGFGGANKDTREGVVVSPTGAPTLRRRGSSSSIRSMSSMTERTFRSPSPHQSRNPALAAAITAQPAGSTTSSHSLSMNAAGTAAAMAAGRSTGSRSRSVPPPPPVPIIPKHVIESQPKQQQKQQVQQTEKQSRRATTLGLVQQPLKLASQKQKTGRSSWFGSAAVGDRASIRSSDTAMDINGNAQPERPGSRNSLHNFSYPSRQRLGSPPPSPTATRSTAAAPAAAATVSLPPAAGKLPRSASTERVMKQEPQQKVAAASARRSASTSRVTSRSYADLSDQTLVYDANSRRMVPRGELIMREQRELAILEAAERPQQQQRKKKQQQGTKTASLAGTHLSQGTMSHAHGSAAPLNRTELERMKEPAPQQPAAVVQAPKTPKSPPLERQLPKITTTALEPPAEEQPAAAEKDLDEAGQPLPALSNSASTPSSSVSSLTALAASQAATSPVAIQSISSPEDGSFEGTLLTEDGRPVLAKRPSIVREDPEREAEEEKLSSAAAVVAAAGSRAARDDLDGVSAKHIHHNPDDATQQAPSTDTQQVQPVLAKPTEKERTRSNSPVRTAHFHPVVKSNLTVRRHSPPPRSISPRKSALKHSSSPRDASPSDSASEANHSLQGDLALQNRKKAHRVSFDDKAVVVSQSPMPPSPPHSPGLSSLPGASEAPPSSNAAHQPPSRSRSWFSNIGRSKKKSDHSNNNFEDDDVVMKPRPALPSFGSVRDKSHPAQHQEERALVRPINDSQPARQPSSSAATAATAATAPLETHNTSSDHAIGYIIGAGAAAVATGAAAAGLERQSSTSPSSSNGNTANTSRYREPLPPVVTSVDGSGYVSDSGASSDDGDDEALADEEEEQEHSPVLRFDEEQDTTVPGNLDDEPIFPTGPTAEDNDPLIILPSPSSPGKSPRKTVPAIEISHPSQENLTAIRGTENDETEDELEEKGEKEDQLTVGTTPVAPAKSSPVRSLFDVPGMFPADTDSDGTAKSSPTQAAFANANNVNAAVPTRQNAFEPITQDDDNSYSPQMPATVFATHMPTLHEETSLRNEKLDEDDSDSEVFSDAYEDLSDIEGDGFLSLDAVVDSPIVPDMVKSPFAASPLTGSPSRKTETLQLGPSPLAKEAAPADTTALTSAAAAGGAVIGMTALTTTAIHKQVNGDAKAGPEGEEDWEKIKAFWRGLTVEKRAQLEKEALQDAADEGDLEDESAAADKKPRRKKSVETRMAEKKAIQELTPAQKTQKPVAVAAPAAAKSTKAATAPAPTPAPIESKSQKPAATRIRKSMRDNAPHATAAATSANDDHFKSTLRPNPPAQKERPTSAYPPKAAVGAINRPQALHSRTMSADSTARSVQGKSGGGMAGLLPSALRRRGSDSSESSFKRARSNSNGASTSGFGSGAAAGAAGAAGFRMSMRGDSKASAAAAAASNSNGGLNHRSSRFSLRSLSPTGSTTLRGSTESSPQFRRSMRDASGGTGFTPMDMKRMSSPGPMANSTLRKGASDSGGGFFSSLGKKRGSKLLQRSKESGGGGGIASFNGKSVRSRFGDSSDEDDDDIFGPTTRASTGGMAANRRSVSTGGAYTFRSRFVDSSDEDEEIPAHRTLDRKGNKDKDHVVPKTLRTGSSMRSASARPTSSSTPLSPLLPEELEEEEEEQQNARPKTAQNGVSAASYAGGVLASATNLDNNNLGTTTLRRSRSGRGQIAPVSPMYSPTTTGAVGLNTGSNATPTRRSGSIMSVLRRKKNDGPSSPTSFSNGSANKIQRAGLVDSAARRDTQLERSTAELAAVRSNSIGSQNRRVNGGSGGNTPRFVPDDDSDDDLDLDDSEDSPVAARRDGTAPTVNGRTASWPLPGPEGQTVVNISAVDFNNEKRKKKFPALRRMFRLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4M1</accession>
    <name>A0ABR3Z4M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thermophilic desulfurizing enzyme family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013107">
        <property type="entry name" value="Acyl-CoA_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08028">
        <property type="entry name" value="Acyl-CoA_dh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="3">
        <location>
            <begin position="39"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase C-terminal" evidence="4">
        <location>
            <begin position="260"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47417" checksum="BB5943B51E971DC1" modified="2025-10-08" version="1">MSATTFESTDPAVYAEYQSKWSTLPTDAAGWIQRAVDVADVLKADAAARDKANKSPRAEVALLKHAGLLKILGPAKYGGGAQPWDVAYRVIREVAKGDGSIGMLLGYHLIWSITANVFGSPEQADRVQKTIVSNNYFVGGAVNPRDNDLTIKADDKGLVFTGHKNFSTGGVISDLTVLEGVVDGTTDHIFAIVPTNQPGIQFQHNWNNVGLRLTESGGVKIDSVPVPWEDALGWDVATKKPDPAVLGIPLASIFLPLIQLIFSNFYIGIAWGALEFAKNYTRKNTRPWPFSGDVKDKVEDEFYVLQTYGNFFAHLRAATALADKANQEAAQLYGKYIAPNSLEERAKFTPEERGAFAEWVASVKVVATDTSLRVTSGVFEVTGSRSTAAKVGLDRFWRDVRTHTLHDPVAFKNRELGRYYLVDEIPEATWYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4W2</accession>
    <name>A0ABR3Z4W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06091">
        <property type="entry name" value="KOW_NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22682">
        <property type="entry name" value="Ribosomal_uL24m-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KOW" evidence="2">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="411" mass="45700" checksum="F93FAD072A3AF4CB" modified="2025-10-08" version="1">MLKLARRTAQAEKQVKRRLKVRERALDAIHGDSVKNVKDVLKEEIQLQARQARRARRETWTMGPLAPQRNHAAAMADEARRGRASSTNRFGGELFAEESLPHWGSLSIRRLRNSSTSPITLREAEARCAWAGSPKTLCLAVGDRCVVIEGPFKGAIGPIKDIQTEHGTLTLEGVARTNITVPTSLVTESSQSVHQMESSMPINAVRLVHPLTDPVTGNTRDVIIRELKPVGFFRDRPTRRSGFSRVVPGLNVRIPWPRTAPTEHEDQDVDTLRIYAEQVTFVPTLLRPPAPEAVLDELRNKYSRFRTRHTPEYIAAKEAEEAAKAEAKKYGPALVKGRQPGLSPPGMRTPLEEFHIQQKALRRARGQPELSDDMLEQIGRLMAQSKISALDNAGMSEVPPSSQSTTQTPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z531</accession>
    <name>A0ABR3Z531_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005139</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="80"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="422" mass="47047" checksum="3462DF97C5557700" modified="2025-10-08" version="1">MASEDAVYRDSSQFRLWSFSPPQLETLREQTNQLAHDSIEERRRETSSNGDDDNKGTPSSSGVVYLTPTEEKMLLDFYTVELLRAAKFTEQPTDVQATAAVFFRRFYVTHSIMTYPPAQLFKTALFFGAKSEGYYHKLDGFAEKFPNTTAADILAGEFLLCQGIRFAFEVKHPFRALEGAIMELRRLVDVDAAAGKDDIDDSRVSDAHRRAREILKFSPLVTDAYFHYSPSQIMFAALWLADRPLVERLLLGETFHRPANMGAAAADVPTPILPGGGNASKKKKNEAAEWERVNGSEIKDRVLDTIKKCSELLATEPPERFTEYWGQPESNNIIKPLLKKLKLCRDPDRFNLVALQQAKKEGAVKSYAKTSTKVAGGMNDDAAVFGKSLGLIGSNAGTGTNTPDNHEAKRRKVDDPFGPPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5H2</accession>
    <name>A0ABR3Z5H2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">2.4.1.25</ecNumber>
            <ecNumber evidence="6">3.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glycogen debrancher</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">GDB1</name>
        <name evidence="22" type="ORF">Sste5346_004980</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.</text>
            <dbReference type="EC" id="3.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycogen debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="5"/>
    <dbReference type="EC" id="3.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11327">
        <property type="entry name" value="AmyAc_Glg_debranch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032788">
        <property type="entry name" value="AGL_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029436">
        <property type="entry name" value="AGL_euk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006421">
        <property type="entry name" value="Glycogen_debranch_met"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01531">
        <property type="entry name" value="glyc_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14702">
        <property type="entry name" value="hGDE_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14699">
        <property type="entry name" value="hGDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Eukaryotic glycogen debranching enzyme N-terminal" evidence="19">
        <location>
            <begin position="42"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="20">
        <location>
            <begin position="145"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme central" evidence="21">
        <location>
            <begin position="766"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="18">
        <location>
            <begin position="1100"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="647"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF14702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1895883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1577" mass="176732" checksum="BDFA839C0EB5C263" modified="2025-10-08" version="1">MIPKTMTSSEVYLLPLNDDGSPQVGGNQYIYLAATSEQPIVVRFAIEGTSSICRHGSLWVNIPEKGAEFQRDHFREFKLDPDFHRTIHISVPIYHPGAFAFYTTYAALPNLSTELSERASFDEEKKTTPLYYIDVAPRLRLDDRPLPLEALSVFSIISKFLGKYPNDWERHLRGISDRGYNMIHFTPLQQRGESDSPYSLYDQLAWDPICFPRGEQDVQDMVRSLETNHSLLSLTDIVLNHTANNSPWLLDHPDAGYNLKTAPHLEAAYLLDTKLLDLGDRLSELGLPTDLQSTDDLVKIMDAIKKECVAGIRLWEYYVLDVELDAANAAESWTNGDVTVPEEFKGGIDGLASLKSADLKTQTEFLTKHALRGNDRLGERHRRTIDAKVAAALLTVILGPASEGAEKEAAHDTMVSLLDAMNVPFYAEYDAEVADILQQLFNRIKYCRLDDNGPKMGPIGPKSALIETYFTRLPRNEQTSKFDIEELVLVNNGWVWGGNALVDNAGPSSRVYLRREVIVWGDCVKLRYGSGPADSPWLWEHMTKYARTMAKYFAGFRIDNCHSTPMHVAEHILDEARRVNPDLYVVAELFTGSEDTDYIFVKRLGLSSLIREAMQAWNTGEMSRLVHKHGGRPIGSFEVDEITRSEVATKKQSQANGHDDNGGDKANGKAADGGELCREIIRRIRVVPVQALFMDCTHDNEVPAQKRDARDTLPNAALVSMCASATGSVMGYDEIYPRLVDLVNETRLYTSESSSRAVKSGSGRNGIGGVKKLLNQIHVLMGKDGYAETHIHHEEEYVTVHRVHPESRKGYFLIAHTAYPGYGNGNGAFSPVHLTGTRARHLGSWMLEVDASEEATKNVLDDTKFLRGLPSRVVDLPGIKLDYNNGDTSIVVPDKFPPGSIALFETWIPAAEHSSGLDTFVTSGAKAAFGELSLVDLNFLLYRCEAEERDSSGGNDGVYDLPGYGRLVYAGLQGWYSILKNVIRDNDLAHPLCQNLRDGQWALNYISGRLERIATKDTHSNLGKPAAWFKERFDAIRPIPAFLHPRYFGLIMKTAYQASWDRAMELMNVNVREGQWFVQSLAMVSIQQTGLVQSASLYPNRLVPSLAAGLPHFAVEWARCWGRDVFISMRGLFLGTGRYDEAKEHILAFASVLKHGMIPNLLGSGGNPRYNARDATWFFLQCIQDYVNLAPDGDELLQTKVKRRFLPNDDTWFDAEDPRAYSQESTIEQVIQESLQRHATGMSFREANAGPGLDMQMRDEGFNIDVHVDWSNGFIFGGNQFNCGTWMDKMGESERAGSKGIPGTPRDGAAIEITGLLYSTLKWLAHRNSKGGFAHEGVQRADGSSITFQDWAALIQDNFERCYYVPQLPADDECYDVNPSVVNRRGIYKDLYKSGKEYEDYQLRPNFAITMTVAPDLFDANHATHALCLADTVLRGPTGMATLDPADLNYRPYYVNSEDSTDFATSKGRNYHQGPEWLWPTGFFLRALLKFDLRRRAADDTEGRTEAFQQVTRRLMGCKQQIQESVWTGLTELTQKNGEYCQDSSPTQAWSAGCLIDLYMDAAEEQAKHKTEKLAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5K1</accession>
    <name>A0ABR3Z5K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF2">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224450" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="35"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="342" mass="37586" checksum="7A559130D723B8A1" modified="2025-10-08" version="1">MRVSSALLGLTALHGASAQQMMRFSCSQLVVERLDPLVNPGDLASPHMHQIGGGNSFNASMDPATHDPVRDSTCTSCTFSEDFSNYWTANLYFRARNGTFKRVPQMANQGLRADGGLTVYYIPPYDGHTNVTAFKPGFRMLVGDAMLRSPRGQQRQICHRCFSTIEQVPFGGAPCTGSDTQSLPSGFCQGGIRTTITFPTCWDGVNTDSPDHKSHVAYPATGTFESTGDCPASHPIRLPQLMYEVMWDTRPFNDKELWPADGSQPFVYSTGDRKGYSQHGDYVFGWKDDALQKALDHRCGNDVCAVLQSQTSEQAMQCTKKQTAVDAVDAWLEKLPGGVELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6I8</accession>
    <name>A0ABR3Z6I8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008902">
        <property type="entry name" value="Rhamnosid_concanavalin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF6">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05592">
        <property type="entry name" value="Bac_rhamnosid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25788">
        <property type="entry name" value="Ig_Rha78A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010631">
        <property type="entry name" value="A-rhamnsds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="5">
        <location>
            <begin position="156"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase concanavalin-like" evidence="4">
        <location>
            <begin position="333"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="6">
        <location>
            <begin position="452"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="7">
        <location>
            <begin position="806"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="926" mass="101971" checksum="DDF988CEC2011D0E" modified="2025-10-08" version="1">MPFLSAPTVEQHATGFGVGTPSPRLSWRFTLAKKDNTVDDADRDWKQTAYDIEVKRQGATDVESYHVESNDSVLVPWPSAPLQSRERASVRVRAFGSDNKSATEWSEWTAVECGLLSKSDWTAVPITSTEKVNSPDNEKALRPLRFKKVFSVPKTSTGRLYITGLGVYRAFLNGQRVGTSEMAPGWTSYNHRLNYETFDVTSLLKDGDNVLAVEVAEGWYAGRLAFHGGLRCIYGQDMGVMAQVEVEAEDGKRSTVVTTDGSWTSSPSATLRSEIYDGEVYDLGQETDWTSSSTEGWTAVRTLDVPAADIISPSAPPVRVTQTVKPIERIVTKTGCIILDFGQNLVGRLRVQLAPLLAQLADSGRQVRVSFVHAEVLEDGELGTRPLRDAECTDTLIVGGDAAEKGLTEWNPNYTFHGFRYASVEGWPEGGDDDEKSLLDNIVADVLHTDMKRTGYFECSHPMVNKLHTNTLWSMRGNFLSIPTDCPQRDERLGWTGDIQVFCNSASYLYNTAGMLGDWLQDLAAEQLLDADDGVPPVVVPNILQTLWPHAPLAVWDDVTVLTPWDLYRSFGDTSFLSRQYESMVAWVDRGVPRGEDGLWVSTLQQLGDWLDPAAPPDQPQETRTSGALVADAYLVRVTDVLAQASAVLGKTKEAVRYTADACRLRSAFQNKYLTPAGLLVGDSQTGLALALVFDLLENPRQRAAAASRLVEHVRAARFRVATGFAGTPIITHALTRAGYPQMAYRMLQEKSKPSWMYPITMGATTIWERWDSMLPDGSINPGEMTSFNHYALGAIVHWLHESVAGVRCLTPGWKEFAVSPIPGGTITSAEAAYETAYGRVEAKWSITDSDKFVLDVLVPANTSAQVILPHERGDKDVTAPEAKDLGRWVGSGRHHFESQWGNLTAWPPAPIKGLFDPEEAESTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7M5</accession>
    <name>A0ABR3Z7M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004617</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF47">
        <property type="entry name" value="ENDOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01220)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045248662" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="140"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="504"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="56509" checksum="9560521A90BCAD4A" modified="2025-10-08" version="1">MAVLSVLLGSLAAASVVAGAPTSLSSSSSSSDTPYYGSHSEYQRHNQHRNSNHFLVSRAPAVALAKHTLPLVRSIPARQGKTPRPRPWHDPNRAPLPLHAGRKLFTVPGGSNSTTNSTSSSPPLAVGVGKAPSANHDIEYITQVVAGSNNLSLVVDTGSSDTWFVRQGFSCVDPQYHRPTLNAACGFGPVFKGDFPGGAIPNQHLAVAYGNPGGPFLEGLLGYSDLEISGLRLKKQTIGLVTRGYWDGDGVTSGLLGLGLPGLTNALPGAPSTTRAGDELDQQRVSVEYAPFVSTLASETNVTQFSLALSRDPEQSFLALGGAPPNIEIDPSLGWVTTPIVKTSTLSNPVGRFMYYTISVESLQYNSSVLRRSTIAVDGQPLRDLPIIVDSGTTLNLFPYEVALAINQLYTPHAQFDPDQGSWIVKCDATPPSLGVQIGDKVIWTDPKSMILPPTGAGSLGNNYCLSGVGARNDAPFILGDTFMQQLVTVFDVGNKEIKFAKRVNNNAPTTTTAPKPSPTKPTLPKPTKGKPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z968</accession>
    <name>A0ABR3Z968_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="43209" checksum="D9815450D1C19751" modified="2025-10-08" version="1">MAIHVLDRYYLGLTAIITVGYQLIFFAIAFTFKFDKVTDFAGGTNFIILAIVSLILGSRDPPFNTVTNIPPTRQLVVTIFLSVWAARLAGFLLFRILRSGHDSRFDDKRDKFLPFLGFWIFQMIWVWTVSLPVTVLNSSTVQSSALSGNLPKFGTANDIVGTIMFGIGFLCESIADVQRLRFRERLSDNDKLAFCKNGLFKWSRHPNYFGEILLQFGIFTIASSDTRYKNGNRPFFASVVYASVTGPVLLTLLLLFVSGLPLSERLAAKKRYEAGGAIWDEYRVYLKRTSILIPLPPSLYSRIPVFLKRTLLFEFPNYVFTPSPDSQPGQGGNQPADAPQQVASPPSRNNIDGNINRDAEHGDDPDAAPNDHRALPPHSASTISSAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA24</accession>
    <name>A0ABR3ZA24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="51"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="360" mass="40098" checksum="86ADCCAB980DB128" modified="2025-10-08" version="1">MATLTETSSASRFRNHVGFDNIPIGEATKSNTLGYTLSISHYGYQPRRRSRTMMVGIDQNVYSDFALQWLLDEYADDGDEIICVHVIDKDARTVEERNYKARADKMVERIKSKIPENCAVSIKLEYAVGKLHATFQKLIQVYEPSMLVVGTRGRSLGGFQGLVNKNSFSKYCLQYSPVPTVVVRDYEKRKKKKDKRSNDPSRHSYANMLAPSNGVHEANSENSSVYNMEARISPDEEAHRVAAAIGLPAAFDPTLKPIDLDQYLGRRSRNTSPARPEPQSVTSETSTIPGSIEVTAASVDSEEEDSADDDEAEFEVTSGQQALQAAAAKESEKEQRKKLHEMEVGEAAALKYVVESDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAA2</accession>
    <name>A0ABR3ZAA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiamine thiazole synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="6">2.4.2.60</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">THI4</name>
        <name evidence="7" type="ORF">Sste5346_003883</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:55708"/>
            <dbReference type="Rhea" id="RHEA-COMP:14264"/>
            <dbReference type="Rhea" id="RHEA-COMP:14265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:90873"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">During the catalytic reaction, a sulfide is transferred from Cys-228 to a reaction intermediate, generating a dehydroalanine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the THI4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.60" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03158">
        <property type="entry name" value="THI4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027495">
        <property type="entry name" value="Sti35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00292">
        <property type="entry name" value="sulfide-dependent adenosine diphosphate thiazole synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="307"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Cys)" evidence="6">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="339" mass="36440" checksum="C3B6B54898007716" modified="2025-10-08" version="1">MAPSAVSHESSPAGTFATPVVQKTLFQSNNENNSATVVNITDKPLGDEVKALMGQWEDNFAFAPIRESQVSRAMTRRYFADLDEYAESDIVIVGAGSCGLSAAYTLGKLRPDLRIALVEAGVAPGGGAWLGGQLFSAMVMRKPADVFLREVGVPYDDEGDFVVVKHASLFTSTVLSHVLRFPNIKLFNATAVEDLITRPAVNDAEGIRIAGVVTNWTLVSLHHDDQSCMDPNTINAPVVISTTGHDGPMGAFSVKRLVSMQRLEKLGGMRGLDMQLAEDAIVKNTREIVPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEALRVFDQRKKENQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBD8</accession>
    <name>A0ABR3ZBD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">beta-glucosidase</fullName>
            <ecNumber evidence="5 14">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_004081</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5 14"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF5">
        <property type="entry name" value="BETA-GLUCOSIDASE M-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="15">
        <location>
            <begin position="754"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1897345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="843" mass="90109" checksum="69B47530087DFE74" modified="2025-10-08" version="1">MASPSEKGTIFLTEERPSNMTANVNNANNVNNVNNVNNVNNGGSTLRSRSLLSARDNATTVPGLITNDTYFYGDSPPVFPSPEMTGVGTWAIAYNKAVALVSQMTLAEKVNLTAGVSSNTGCSGMIPAVPRLNFPGMCLSDAGNGLRGTDFVSSWPSGIHVGASWNRSLAQQRAIGMAGEFKKKGVNIMLGPVVGPVGRTVLSGRYWEGISVDPYLAGALVYETVTGTQQTGVITSTKHYIGNEQETNRTPEGDVQSISSNIDDRTMHELYLWPFQDAVFAGSGNIMCSYNRVNNSYGCANSKTLNGLLKTELGFQGFVVSDWAAQHTGVASALSGLDVAMPNSVYWGNYLVQAVQNGSVPESRVTDMATRIVASWYQMGQDTDFPTPGIGMAVDLTQPHPIVDARDPAFKQTLLDGAIEGHVLLKNNNNSLPLKAPKFLSLYGYSARSAPQNNYEGSYSAWVFGAQAANITDVLAGFLGTTGVDHLAIAPNGTLYSGGGSGANSQTTVISPFEALTQRAWQDGTQMFWDFDNQKPSINAVSEACIVFGNVWASESFDRPAVTDDYTDQLIANVASSCSNTIVVLHNAGVRVVDAWIDHPNVTALIFAHLPGQASGEALVSLLYGDANPSGKLPYTVAKQASDYGAVLEPDLPEGIFANFPQANFTEGVFIDYRHFDAANITPRYEFGFGLSYTTFGYASLNIEKATLVTANETNLFAEYPAGAVREGGQADLWDELVTVTAEISNTGSVEGAEVAQLYITLPNAGVNSTLSATPDIPIRQLRGFDKMLLAAGESATVTFALTRRDLSYWDINAQKWRLQPGTYTVSVGASSRNLPLTGTFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBN3</accession>
    <name>A0ABR3ZBN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="702" mass="76181" checksum="D4546DFA046E7F47" modified="2025-10-08" version="1">MDGLYPENDPPVQLCSDGNEQRDVTESNSLFSGLGCDPAADLGLFLDGEIFAGQSDEQDSLFGGDAEMQNLLARLEGEEPRQEHPGQLQEPASPLSLPSALASSSLPLSSSALQQSDSVEPLSAVSTLHHDETQNQQQFDDNVPSQEEDALLLLQDFGLDGNSSVNFDFDVDFDFGLAVEQEVTRQAQNELEPGTEKDEVTPVSPKYLVTTATITSNSLTSLTPVPEAAADSGLVPLNHAQPSIDKPSPTTDLGTRGDQECPGPSIINIDDNDSDGDVVLLSSRQVECQVQGLVSTPPPPPPPFTVPVPIPHYLELRPRCPQGPPPPRIDLGSYNVEELLPFVQLYSKLSLRGIQERMGLDVDAGKLIVMRCQDHLADPAHAVTFSGSNPAALRALKVTLIYSALALLKDSDGRAGVGSSWFGRESTLEPTSEHMWPEDSTTLTLLFIQLLYRLTRNANSRERYRKAREARAASPVPTFGELNPPQAPEASTSPEEPQLQASNEAPKEPTPPKEPKPRKRKRETPQPKAAAKPVELPVPVPVHPNAGLRYSSPSVLREALLATNASNSTTPASESDKAPSPTLTAPSPATAFAEPGFYYVSKRAPMNASIRYRVNVIDGHAQRRAIPQINLCHDGDIRAAGYSHLTDMCHRLCREVDSVSIMTILGLERVCSDSDWDRVINRVNDDELLMDGEVKILVRLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCK5</accession>
    <name>A0ABR3ZCK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1898007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17136" checksum="BF3BABC16A2FE606" modified="2025-10-08" version="1">MAPAIASSTLHGAVNGTHPHCDRLTAAAAAAVASVSSSSQSTRAADDGTASISVLGYVSLGVIGFAILAMASCWLYVYRKGDNVRKQRRPAPLPTATLPLCMADVEGRNSLGSSVRSDIGTHVNLATSGLHNIVEEGSSSAAQMKPAPKKPAKNSVYFEKLERDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ6</accession>
    <name>A0ABR3ZCQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Clathrin associated protein complex medium subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">APM4</name>
        <name evidence="9" type="ORF">Sste5346_003532</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="168"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="437" mass="49298" checksum="586FD45CFB5395C6" modified="2025-10-08" version="1">MLSGILIFNQKGENLIFRAFRNDCRPRLADVFRIQVISNPQVRSPILTLGSTTFSHVKHENIYLVAITKSNANAALVFEFLYRLIALGRGYFGKFDEEAIKNNFVLVYELLDEIIDFGYPQNTETDTLKMYITTEGVKSEHRAEDSAKITMQATGALSWRKADVKYRKNEAFVDVIEDVNLLMSATGAVLRADVTGQIVMRAYLSGTPECKFGLNDRLLLDSDTVNSLPSGNRQGSKATKAAAGSVTLEDCQFHQCVKLGKFDSDRIISFVPPDGEFELMRYRSTENVNLPFKIHAIVNEVGKTKVEYSIGVRANFGPKLFATNVVVRIPTPLNTARITERCTQGKAKYEPSENNIVWKISRFTGQSEFVLSAEAELTSMTNQKSWSRPPLSMDFSLLMFTSSGLLVRYLKVFEKSNYSSVKWVRYMTRAGSYEIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD31</accession>
    <name>A0ABR3ZD31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenylosuccinate lyase</fullName>
            <shortName evidence="2">ASL</shortName>
            <ecNumber evidence="2">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ADE13</name>
        <name evidence="4" type="ORF">Sste5346_003593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="3">
        <location>
            <begin position="374"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="485" mass="54253" checksum="3AF36E27BE1D21AF" modified="2025-10-08" version="1">MSGFDTYKTPLDSRYSSAEMKQLFSARSRHSVWRKLWLLLAEAEKEVGVEGITDEALEQMRAHVTLTDEDFAVAAIEEKRRRHDVMAHVHAYGQVAPAAAGIIHLGATSCYVTDNAELILMRDAMDLLIPKLAKVIHNLSQFALQTKDIPTLGFTHFQPAQLITVGRRAAQWIQDLMMDLENIQTQRDRLEFRGAMGTTGTQASFMEIFHNDGSKIDKLNEILCAKTGFPKTYDISVQTYSRKVDLDIANAIAGLGATAMHITSDIRHLAHMKELEEPFEKDQIGSSAMAYKRNPMRSERICSLGRKLRSLPANFADTYADQWFERTLDDSAIRRIDIPEMMLLADAVLIGLDNVSSGMVIYPKRIHAHVMEELPFMATETIIMKIVAAGGSRQEAHEEIRVLSHQASEVVKNQGGKNDLIERLKATEYFRPVWAEIDGLLDPALFVGRSGEMVQRYCGAGGPVEKRLGAFQEYISKTGAAQLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD62</accession>
    <name>A0ABR3ZD62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="229"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="561"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="642" mass="71163" checksum="29E61B9C027A3360" modified="2025-10-08" version="1">MGPKSTSSGAVGADNITAPGLSTDLTLSLGLHPTTHFKYIGPGSLHEDLLLDFIEPAFRPHSDQDASKFCRVAEGVTFLARADATVHTNASNTSADGANVADVERLVHPHGPALIDLYFRIVHPSYSILHKDILLEQYGRKERGTVVSAPLLAALYLLALDWWEYDVALGQGVGRGSTSSRDGNTKPDGEALARIASQSLSAAIQRPKLSTVQACLLLLQRGATTGNDSWVLTSQLVAVAEELGLHVDCQNWSIPIWEKGLRRRLAWATFMQDKWSSLIYGRPSHVQAEHWRIPQLDLSDFVEDNSQTMETDDDVLKGRLLFIHLARLTEVMAEALATFYSHDPQHHDVFSSSDGMQTVALVKPVALRLRAWATALPSCLRMEAVRPHKLCSNGYLHLAYFVTEIMVYRCIVRSLARKPLLDAETTMASAGPPLALVNLCREAAKTRLLHVMRFVEALRPEHLQAFWWFASAKSLAYIRTYVSMLWATSPNNAEAEMYRQKLDEFRWSLRVRARGVAFVTAALRDMGESLEDIDMSSPPFERRAQAEVKKRELRGGVRSYTADTSTGRAKGSTGGADTPVVREQERTPTSSMQNFGTDLDHLDDFDDMVLQTTPEFLADFGVDASHTFFADINSLHLSMDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD8</accession>
    <name>A0ABR3ZDD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003573</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="105"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="615"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="645" mass="67744" checksum="6E647BDDDDE7F30A" modified="2025-10-08" version="1">MAQTTPASGQDAPTRDFEADAATIAAAPTPSPQTDEDEKSTPRTGSATEADAIVAPVDAKADETAAAASAAPHDAPQDAPQDEAPPSPPPAAAADKLAKPQIILLMSALCMSVFLAALDMTIITTALPTIAEAFGSSAGFVWVGSAFMLASAASTAAWGKFSDIWGRKPVLLTANVIFILGCALCGAANSLTMVIAGRAVQGMGAGGLLTLVNIIIGDLFSARERGKYYGMIGMVWATASALGPVVGGALTSNVTWRWCFYINLPISGTALVIIFFTLKLPIPDTPLLAGLKAIDWLGALAITGGTLMLLMGLQFGGTSHPWDSAIVVCLIVFGFLTIVLFVVIEHWVAKYPVVPTHIFKSRSNLACLLVCLFHGLTFTQATYFMPTYFQAVLGATPLLSGVYLLAMSFGVSVCAASSGIYLKKTGRYMDPIFAGFFFTILGTGLLIDLPTGSRTPSFSSAWARIIIYQGIAGIGTGLLFQPPLVALQSNVPPQNNASVTSSFALVRSMASAIAVVIGSAVFSNKMTDQYDTVLDAVGGNATLASGLTGANAQANLFLVDTLPAAAETIVRLTLYKAIRTIWYECVAFAVAGLLASFLIRKKALRVSHEVVKTGIEGEQERRRIALAKKEEKRQQKANKKTEGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE52</accession>
    <name>A0ABR3ZE52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="233" mass="25067" checksum="F19F1049CC754C1D" modified="2025-10-08" version="1">MSDLLFVNFSDKDPAPSGSLTTDGAGPSFSFGAPPKSDIYASPRVPQVLHDYTAPVVCKRIPRESFKSLAVTASAAWRTQFDQAGLVFTLPTKTNPDPDTENAKVVERHPAWVKAGIEVNDGCPCVSVVARGPGGTGGWSDWSLIPLSLAGESLGGEVPVSLEFTREKNALMVWLIRGGTKLFIRKVPWVFLEHDTLGEDVLVGAYAAQPDPYDVSKGESLQVTFSGFKIETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL2</accession>
    <name>A0ABR3ZEL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="4">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ANB1</name>
        <name evidence="6" type="ORF">Sste5346_003015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0385">Hypusine</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="5">
        <location>
            <begin position="87"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="161" mass="17567" checksum="C08C78E1A147E672" modified="2025-10-08" version="1">MADDSQHEHTFDSADAGASATYPMQCSALRKNGFVVIKGRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEELCPSTHNMDVPNVRRSEFQLLDISDDGFLSLMSDDGETKDDVKLPDGEIGDKITKLFKTDEKDTNVTILAAMGEESAVDAKEAPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEW9</accession>
    <name>A0ABR3ZEW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17221" checksum="89AA5048DC09220B" modified="2025-10-08" version="1">MDEGTSRDRNIGVSLHRIHLVGFNDCTAAYFCAIADAAVRKEKKQSISDSPSWKALGAVVFHDIVHSTALYQSNRLGSTAGDGELFPLNHMDLGTQNTLVDDELNFLAIIDWEFAQTAPWPVNYYPMPFPFTDSDAETQAILQDPTHLAHENVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF80</accession>
    <name>A0ABR3ZF80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="490" mass="54628" checksum="A1D923578B2F6FEC" modified="2025-10-08" version="1">MASTSTVSMASFFNTAPPPASISKADSSSGCRAPPPTRVESSADVDADEKLTGDRHRFDALVNRLQQKLSERSEQGSKSIAPAKGVEKMPNNTGSSTESKVSQESKAEKREVLIVHGSRQEHSRVSESSRASSSSFTDVQKERLLASTTSFAASKLREVESNTKTGEPEVEPNTETQPPPLPPRPQPKESTRESTGKSNPPSAETRRGKSTSELDPNQPPFQPTNVHASFSRPSYPGQQAMVLGMAPQPDHWRPIHRQAQSLPRAPVSVPVPAPVPAPFITAPMPLLPVPPGPPVPPMPRLPYAGNANSMDNAMPRWPMSKRPSKRRHDITPFVPISAAEQQKIEEHIELLKSTIPNYATLSKRRQEIRTVEGGSCPWTDSRQWQQGNPQLQQQQRQFSQPHVQSILQPEESAQQHQQMQWHQVQRLQQLQQQMNLMHLTQQDQQFYQQQHPAQPAWTEKPMQPFHPYALYNPNAVGVPTWPMPMINMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFD3</accession>
    <name>A0ABR3ZFD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002814</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="58560" checksum="39F80D11C56BBFCB" modified="2025-10-08" version="1">MACCYIAAYCVGQLVKASQFFDLDNGIRYNDEDGIETFIRDIDNDSEKAAIPKPPAADGSNFVVSIDGMTCSACTSAVEDTVGKINGLVRIVGVLQILYWGNIAFLPGAIRALLNAATLATAFYIQVQLVPWIHKDGWGWINWEKLMSGQGISGGGGVVNMNTLISLSIVLGLAVSLCDFIFGGASTTSSPNFTTVGLTLVVVSGRYLEASSRRSAFGFFMGLYKPLHKTNYSTLHLSRQVVPASYLRSQDSIVVWPHSMIPCDCYVSDGKSLVNQSMATAAAAKRGILIDGGMDIIKRLQRSRTVIFDKTGTLTEARLNVEDLVTTPTCAVEERFAGGHPVARAVFGAGLMRLGHKNTHHVQICRNLRNVAQNAGLGVSGKVSLAADQWHSIHIGSRRYLQQSGVEDLPSSSENSSREGGVLAVYVAVDSKYAATLWLVHVGIGLYRDSTYTPMGASLVILNSRLDSASLLYRMAAITTRQFHFNLFWVFGYNLVALSMASGLVEPFGFKLTPSIAAFFMSLSSVFITAQSINVTAKLDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFE8</accession>
    <name>A0ABR3ZFE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_002821</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="132"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="212"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="366"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="412"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="491"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="568"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="568"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="626" mass="67670" checksum="9BDDD4B473321FC2" modified="2025-10-08" version="1">MSMSSATDNRSSVSSGNTPVPAASTTTTTPQSSSSVPAASSSSSNEDNLVCRWSQCSERFTTPEILYDHICERHVGRKSTNNLNLTCQWNQCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKTFKRPQDLKKHVKTHADDSVLAPRPGQDPTGGMGSSYRTHTTSSSYYDHNGHIRTNPSAFNQPHQGGGHAGYYAQQPAYGNGLYFPPALNPRSDGFMGGHHHSHQQQQHHHQAQHHQQHHAPQHHMASGPADVGHGGYPQRRNLDVLNDFFGSLKRGNVDPSSYAQVGRSLMPLQTGGAAGGGGGVATEFMPQPPHLLASAAQQQQHNPMAQHYFLPPIPNLRTKNDLEEMDVLLEQMQTTIYDNSGASPTPNTHAFDLRNNPSPLARPTLVNDHYANAAVSAAHMPSPLTALSHSQSGGSPAVTPPSSGASYTSGHSPSASSTGMSPSSRQAPAVMATSAAGTIAYPHLPTSSGVAYPGSAAPTTLGSSFSYEDRPHRGGMLQSASRKVRPEEEDRRQQRQGSGSKEGASSPSAASDASSEPESYDQWLNNVRMIESLREYIKTRLTRQEYDPSRDARDSRDMPAYGRGRDLPEPPTSTRLPSLKSVSEAPPPPLYPTLRLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFN1</accession>
    <name>A0ABR3ZFN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pre-60S factor rei1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">REI1</name>
        <name evidence="11" type="ORF">Sste5346_003507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="146"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="337"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="595" mass="65692" checksum="9CB7807FA01A0CAB" modified="2025-10-08" version="1">MTTIASGRPATKPADEGAPATHQFSCNSCQVAFRNVDLQKSHMKGEWHRYNLKRRVINLPPISSDLFAEKTLQNRAGAAAEAGRVGFERNCDVCQKTYFSENSYQNHIGSQKHKAKAAKAGPKRAKSSKAPIDDASTVISSTFSLGEPTQKVQPTVVDTETETVGSEAEEEFSQVVEGLKKATMEEGHSPVKRPANPRLSAAAQHKGEHPLDSEEADEEETEESNTPTAKQSEPAHSLKLCLFCNYASPTIALSVAHMSRFHNMFIPEKQYLVDLEGLLSHLETRIRDDHACITCGKVRGDVFAVQTHMRDKAHCSIPYLTLEEQVDIGDFYDFRGTYSDSDPEDDDDDDDSDEEGEKKKAGASKLGAKRATKTTTADGSDITGGEEEDGWETDSSASSLDSADLTAVPADNHIHQYERLDKHPHHSQTDPRAHHQPDGWHSHAHKHNHAVYYDEHELHLPSGRSVGHRSLNRYFRQNLHNYPSLAEREKQMQLAIEAGVEFDSEDEDEDGEGVEGEAASLALARRSNAAKARAVSTRPAPRNTMGLTGVTDKAKANLLKVERRHELAQQIAADKGRIKFSANSIGQSFRFLGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ0</accession>
    <name>A0ABR3ZHZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membrane fusion mating protein FIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033481">
        <property type="entry name" value="Dni1/Fig1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016509">
        <property type="entry name" value="Fig1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28092">
        <property type="entry name" value="FACTOR-INDUCED GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28092:SF1">
        <property type="entry name" value="FACTOR-INDUCED GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12351">
        <property type="entry name" value="Fig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007138">
        <property type="entry name" value="FIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28925" checksum="B0FFFD93AFFE389B" modified="2025-10-08" version="1">MPSGGVVQVGWYRYIPFLGYHHVLMILIAVAIILLSLLLAGCSSSSPLIPGIFLLSLYYEHYTAVPSTAQVDYNVNSAISNIVGSAHMQARVGYFGICVNPDGGSWLCSNNATALANEVSVDQDPLNLIWLASQFKDMIVFPYLIIIAIIFAFICLLLLATFPGWHEEEDSEGSEREVKPFPSRFVSQISLAIIFVASIFVLVSVLWQHTASVAASIIAQDLGNGSVKSGVGASAIAMGWFSFALLIVVTIGLLVMILSIRVLNQLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI02</accession>
    <name>A0ABR3ZI02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_002597</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="32"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="532"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="539"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="586"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="607"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="651" mass="72274" checksum="7F7E67238C5D6A27" modified="2025-10-08" version="1">MADVLILRGAEVLRKVSFNNNDRKRFRRLTLSDMAEPEPGALSSAPGLPTPTSRINKSEDTLTDSEIALTPEGSSGGSNPDAGAAADASAGSPQLLPEHAIADTPTLGPTMSGPSSPRYGASRHPSFSGSSSYQEDWDIPPLDRLTVLDLLDNFALPQQLEKLSKGISAQTRKLKKSRDALKSRSAVARERMVEEWRHRVPSAEEQLDRYRKRMRTSVEKLGRQWNDTKVITLREKVSFICGVLNIFISGYLIGGWPEYMHLWYTVQILYFMPIRFYTYHKRGYHYFLADLCYFVNFLLILSLWVFPSSKRLFVACYCLAFGNNAVAIVMWRNSLVFHSFDKVTSLFIHVMPCATLHCIVHLVSPEIQKVRFPAVYAIQHAPPGTYGNYANVISMLAWSTIPYAIWQLSYYFFITVRRREKIAAGRPTSFTWLRRSYSKTWIGKIVLALPNALQEPAFMFIQYNYAVCTMLPCPLWFRYRWASAAFMMGVFTWSIYNGSTYYIDVFGKRFQKELEAMKQEVAKWHSLESVAGEGSTTSGAGGGASSGSAGAGDGATDNAGGTLSNLTSPPLEPLSERGTDDEDDEERRHSIDAIPLLDRDANDDGSDSASNSGAKTPGVASAAEAMAAATMTGATGSDWDVSAKDVARRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIE9</accession>
    <name>A0ABR3ZIE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="787" mass="82647" checksum="83047B04BD8C4E69" modified="2025-10-08" version="1">MAPLTDAQRDAAERRWMEVSRDNKNHNRRRASSDSQSNVKNNRDAQSGSAGGDSKTPTDFGKGKFGGASGGGNFGKGFKSNGNNNDSDKGKGNSDDDNNTNTKSKGGNKGGNSNRGGGNNNNNNNNNNNNDDNNGSKSSSSSNTNNGNGNGNGNGNGGSSNSNDNNNGNGSGNTNNAGSAATTTPAVIAGDGGSSDSNGAQQFSSESIGDTTTSTDTPTAAAAPTTTEPPTIVLTTSTIVTTGPDAVVTSFVPLITTAATSDTTTTTFHRPFAPFGPFGTNFPGFPTFSRPTGKDSSDDKKHKGVNGTTTDDDNNNGNNSSNNKGSNNNNNNNNKGNNNNNNNNNNKSKSLDPTAERALISVGSIGAFIVICFIFWLVWRAFKKQKQKKLQRGNVSSFPSHDGPFAAISRLPGRVYDRVVNKIPFASRQRKAWQTLEETNSSNAGPMMTNNVAPSSMARAGGPSYPEKGGDTLRTFGFESDLPPALPSLPSQVYYSGGPGLGLQFQSPPQQTEANSVNRMPTGLVRSNSNVSAFTHSPAASFSSSIVSAQTVIPVAAPYGVNNGTFNMGQPTGPVMVVNEAGQQYLTDDIGSAASTMRSRMPDPFYNQSQLARQPSDAYDPARRQVNRASELSSLSSGFGDGEILMLASDQQQTQTGQMPMSAQRPSRVPPGPPLSASAGAAGRFSWMRKQRMSRETVYTESSEDQPAKFRSVNSWVKQQTGRVRRGQASIDTTSSASAGGEGSDMAVVVGNEPGIPHPMPAEQRLTMMDDGEEPRRPDTVPGIQMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIM9</accession>
    <name>A0ABR3ZIM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002232</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RPAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039913">
        <property type="entry name" value="RPAP1/Rba50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013929">
        <property type="entry name" value="RPAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013930">
        <property type="entry name" value="RPAP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483:SF18">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08620">
        <property type="entry name" value="RPAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08621">
        <property type="entry name" value="RPAP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RPAP1 N-terminal" evidence="4">
        <location>
            <begin position="105"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1 C-terminal" evidence="3">
        <location>
            <begin position="336"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="52755" checksum="A50C8C6683DB8438" modified="2025-10-08" version="1">MDGSLRILDIQEKEVGAATPPSFPYPRSTGFPEPKKRARFASAFKQQRQAAEAAVAAGIAADTPKPTFGPAPPTLSNSFPSSSSSSSRPSAPKQSQDASFDEKAGIDRENREMLSSMAPDEIAEARNELLSNLSPDLLQILLRRANLDDGSNARLPGEELSQPGPAAPTPEIRIQDSSADTAETEEEPKEPTKLKKKVLFASVEDADDKDDKPKAAGKNTGDAALFGNDEKVPAADDLAPISSPEKVVQNHDHDHDHDHDHAHDGPGAVHFPHAPAVPDLDPNDPDFLQNLHTKYFPNLPADPARLAWMAPLPTADSPADRESPYYPGQESLAVSQLRFDFRGRLIPPRASREIPVTKGLHHHGVAPEAAGYTIGELARLARSAVPSQRCVAFQLLGRLLYRLGKGEFGGGGGETGTGMGSAVDEATSDPRVQLAQGIWRSLSEGRVLDTLREAASMEEGQGHRGSRAYAIEAIWLYEKGGWKERWQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ34</accession>
    <name>A0ABR3ZJ34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="124" mass="12888" checksum="30623161A19B22AF" modified="2025-10-08" version="1">MSSSPEDVAVLAGQAKNFAPVNDVQPSFFLSLAPATSSSYPQRKASVPEVDAAPVVAAATVTAPAPTEPVAAAAVDAKQRRSSSLSSTGSNSTSTGLRILKLGPVHWGEHLDESKHDWHEVVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJS9</accession>
    <name>A0ABR3ZJS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450 oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002041</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="59790" checksum="73D2965425BFA478" modified="2025-10-08" version="1">MLIPPNVLLAMAGLLLVYGLYRLSQVGKRDPRLPPGPPTTMLLGNAHEIPATGLGKKFMEWSETYGKIFSLKVGPGTIIVICDRRAVYELIDKKGSIYSDRPPNVVPLFITRGNHMTMECQTPSWREKRTVVTRNLNPKSLDEKHFRVQEAEAVVFMNRLLTDPDRFFQYARLYASSVAAILAWGFRAASLDSFWFKDVGAMIEQWLEAIEPGANPPVDLVPWLWYLPGKWKQRAHRMRAYMDATWTHARALVDARRDRGDRRACMIDDKLDAYEKDGWPMSQHAFNLLFGELMEAGADTTANQILTLVLALAKNPHVQEKARKELDAICGTERAPLFSDFARLPYINAIIKEGLRWRPTSDLGLPHTVTKDDYYNGMFIPKGSTIFVGVWAMHMDEQHYPDRDTFNPDRFLQHSSKLANDFAVGPDYANRDHYGYGAGRRICPGIHLAERSMWRIAAKLLWAFEFAEPLDPVTGKVQPLDPDAYTSANLVCPLPFKVRITPRSQAHVEIIKRELAGAEEFLAQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK22</accession>
    <name>A0ABR3ZK22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ELYS-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025151">
        <property type="entry name" value="ELYS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13934">
        <property type="entry name" value="ELYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELYS-like" evidence="3">
        <location>
            <begin position="40"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="324" mass="35786" checksum="77338747D6371D69" modified="2025-10-08" version="1">MSGRLDFRNFSDVFGNGDTLPYDAHVNRDIESKRKSLGGVLFVDRVFTALGISKVKMYPPKDTRTLHDLFQQILASKMTTHHKLSALYYLLLDHDEGLSARSKISDNFAAQTGMPKRYQIFMSGLWHMDRLQFGVALEYLAHPSLLPEFADNIVTVLVRHAENNDYSLALAYYATVQPVLKTQEAVELLFEALSRTDVSEAFYYTRTLAGPARQQLFEQLVGSVLKDAGAGGASSSSNNSGGGNLDVAGRSAELISLPLDAQEETWLRAYLTVGDGRKLKRAKDTMIMKKIVSGDVDLSEGSKSLTGPWGIVLQGFRHETGGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKX4</accession>
    <name>A0ABR3ZKX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein YAE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein yae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">YAE1</name>
        <name evidence="12" type="ORF">Sste5346_002479</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">May form a complex with LTO1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the YAE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038881">
        <property type="entry name" value="Yae1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829:SF0">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="11">
        <location>
            <begin position="149"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="312"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="348" mass="36963" checksum="260BB8ABE391F8C4" modified="2025-10-08" version="1">MHQRPPADPDNKDDLLVPADISFATMTMDRNSPAAEFDNFIAPDPVDTGTIYHGDGLADGETAESTGVTDRRIETTVQGRSAVELFDDIFGSSPDEHHQRGPRSPSGAATASSPTIPSSISNNDPSTRHDDHRHPSDMNRLQQEHSTAGYREGLNEGKNSTLQAGFDEGYSLGAAIGGVVGELLGMLEALVVSGEEEGQAAAADTENGDTLTVLLGRARRDLTAPSIFAPDYFATDGTWNYDVEASETAAAIQANTTQAVEAADATFHATIFDVANAHPLVKTWRGIVDRQLERRRIRWGKEGDDAALAKALGLKDEDEGQSEKPAADAAAPTATARAPANNASALDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLG4</accession>
    <name>A0ABR3ZLG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734989" description="Serine peptidase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="63029" checksum="A509B239B01FEEA6" modified="2025-10-08" version="1">MKFSASVAALVLAGASTVAGIRHHGNMKPPPLSLDNVVSRRTANHDNGNVQHARKIRGTNNVWESSSAASPRAVLNNNPEAADQTTTYGQGTFEQQIDHTDASVGTFSQRFWWSTEYWTGPGAPVVLFTPGESEAEGYTGYLTNKTLTGQFAQAIGGAVVMFEHRYWGESSPYADLTTKNLQYLTLANAIADTTNFARNVKLPFDNSTGSNAPNAPWVLSGGSYSGALTAWVEHLDPGTFWAYHASSAVVETIGDFWQYFEPVRAGLPKNCSADVTLVIDHIDSVLASGSDSEIQALKNKFGLGSVEHNDDFASVLVSGPGAWQSHDFDTGYSTVFQFCDYVENAVAGVFNSTCKPSSAPGTNGVGLKKALNGYAKFIKEFVVPGYCESFGPAFQGTYNTDCMNSHNASNPIYTDISVDNAIDRQWVWLLCNEPFEFWQTGAPEGTPSLVSRLVDYDYQQNQCALYFPEVEGYTFGSNSRIGKTPEDVNKYTDGWSVTNTTRLIWANGEFDPWKDATVSSDYRPGGPLVSTPEAPVNVIPGGIHCSDLIYANAVGNEGVMAIVQDEIATIKGWVEEFYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMN6</accession>
    <name>A0ABR3ZMN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001736</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF27">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="101"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="965"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1203"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="998"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1082"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1133"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1207"/>
            <end position="1227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1299" mass="139882" checksum="E14448B4AB6AEE58" modified="2025-10-08" version="1">MSELQFHSDVDDINQFPAEASTQLPMNEDDSGNLAPDPFTLGAVDEQGPSYATAAATTAMDNDSGPAGQAAGNIADTGMIEVASPHFDDFQFSPYPGLHDDGNTMAALQDDSTNLFGSPSPASALPSGVQADITPATIEPVDSVKAKPAPVQTDDKDEKSAEPTAPKAKPKPSGTNKVGKAKASASQSNDDKSPSKPRQNQAAPEEAISDDGSQDGSEHDRGASMLEEPVSDEFGLTLTDPASMERAGGSGSGSGGHRPSFLVKDERTGSTDATPAWSELKTKAGKERKRLPLACIACRRKKIRCSGEKPACKHCLRSRTPCVYKVTARKAAPRTDYMAMLDKRLKRMEDRIIKIVPKSEQDPIVTTSVNRAIVKPGIPGAGASGATNGTGSGSGASSAKGSSSKKRVADEAFGPELDHWARIGSKSRAANVPRPHSMLLQQESEDNKLFQEGADALPSLELQEHLAEVFFENIYGQAYHLLHRPSYMRKLVMGQLPPVLILSVCAVAARFSPHPIFGNVPNFLRGEEWALHAREIVTRRYEWPNITILTCLLILGLHEFGTCHGGRSWALGGQAIRMAFALQLHKDLDKDPNPRSGSESTLSFIDREIRRRTMWACFLMDRFNSSGTDRPTFIKEESVKIHLPIREKYFQLDMPGPTESLAGPSVTTAAADMSKDDGQLSDARDNMGVAAYMIRAIAVWGRVINYLNQGGKELDPHPMWSPESGYTKLVKQVDEMLSSLPPSLVFSTENLHLHEAEGMANQFLFLHIAIHQNILFMNRFATTGNLQQDAIPKAFVTKAGAKAFAAANRISELLKDAETFLVAAPFVGYCAFLSSTVHIFGIFSGNPAMEATSKQNLTTNVKFLSKMKRYWGMFHFMAENLREQYRQCADAARQGTPANENAAASSPIFQYGDWFDRYPHGVSGSDFNGPATYKKKEKGDDAVLEQKPELHTVEEFFVAVAPQNAEGQAGPSGTQAGRDASAAGSRTGSQAKRKSTVKKASASVASSSRTEQQQPPVDQCMTELGAGNSDALQQQQQQQQQQQQQQQQQQQQQQHHATLQQQGQPHPQAQNTHHGRHYSGSLGRQSSGPTNFNPMSMPQSQAPVATASFHASMTPISPVGVNPFAHPHHPQHQQHQQQQQQQQQHQAFYQPDLLALSLAQQNNSIMPQLDRQLVFGAYGNLDIGGTATVNGGHGTLDGMGWDTSGSASGGGHRGSGQGAGQMGGGSDHGVPSAADAMNPFGQGHEQSSAWFMPFNMEPPEMSQDLSGMGGLDQFGNIFGNNNVSGGGNGGLGGLHHGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN61</accession>
    <name>A0ABR3ZN61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitosis inhibitor protein kinase swe1</fullName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SWE1</name>
        <name evidence="8" type="ORF">Sste5346_001569</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF196">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE SWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="825"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="298"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="545"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="698"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="860"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="54"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="711"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="754"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1237" mass="132186" checksum="6F69208840CA399C" modified="2025-10-08" version="1">MSFSSSGGGTLALPSPTGLHGDSGPSSVRSLRRSLSRSPSRFHLLRAESHNSQHSDSSSSSALPSPCPQPHTTTPAHAPPASLSTSSSASSISSDYNFTSSTPLVTVAGTGAAPHSAQSAPQTGLFSTPLRSGVKLSLRSVRPKTASAKPVSRPRPSPKSPLKRALSINSDMGNSAPSTTPQSAGPSTALSEPLLGQENSSSGGSKFSSLLLALGSSPRNRLDKPSRHSMHLDLSGDSRLDALASAISSPLKRSDAIMNFDQVNPGSPVAKRRSLHGIASLGGDFNVFDFGSPAAVPPARSSFEIHDDSNSREQQNPTATASPAPAPASSASISSPAPAADLNSPSTSSVMAKRTSSLRKSTLQQRHDPRSSWGRRQGEKYLAQQQQQQQQAAPSSPQLQQPKRASNEWLFSAPHTRNKPRASLDQLLKPEPRDSPFKPKGPLPNPSVHPVDRPTGLAGSTHLHQPHPLSRTLTTSSSGSSLPDDSPTHFPVQHPPDRPRPSIFARSLPLNAHRPRPDPVATPQYKSARPLQSVFASAGLVSKMNKNGEDDSLQQANGRPMIMPDTPCKKQVYPSNTYPPSSGSGRKQQQRRFFFSAAPETPFNSSTGSAAQPRGSPANNASESVANFFKRRSTHTRKGSILSLDGDISDSQGAADGFDLPPTPTKSVLAKNLFGSASKGSSTPIAIRDLAASGPGPLSFTPDAAVPRQAPMPISSPIESSSSEKMSPKTPREHSILHNNDFANSMAPPDASRLSISGGPSQQLNAPNKMSVALPSNKSSSMIFPPATPTTDREAYANFVDRRVSITPVHGAAPKDTDMVLTSMFGKVECVGRGEFSQVFRVNTRDSSVYGNGPLDYFSATPSKRSSTRGGNNTPSLARSHSSSAPHVFAVKKVRLPYFGQKEREAKLREVAVLEAVRDRENVLQIFDHWEQNGHLYIQTEYCDEGGMDSFLKKVGENGRLDDFRIWKILLEVSQGLRYVHDAGFIHLDLKPANIFVTYEGHLKIGDFGMATSWPAPKGIEGEGDREYMGPEILQGRYDKPADVFALGLIVLEIACNVFLPDNGPIWVALREGDMSVVPSLTAGEANALVRDSAGMPVVGDFDNSSLDGHSLTASLDLASTTPGRNPPVDFSRSIRPGRNLFGSLSSKKPMGLERPPAFMVNASDAGSLDSVVACLINPDPARRPTVHEILEMESLQWVFGRRRAPATIFEGNWGPEDDEDNVQASFVECDTEMTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPW0</accession>
    <name>A0ABR3ZPW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="137" mass="15351" checksum="8751AED6795D203C" modified="2025-10-08" version="1">MSGETVPTIPKTPWPPQQAHLSAPPSKRRPSMPPLPSLRVVNHDVPIPGHYRAHVMRAIEGLYDVQAAYDKAKNEANDAVEAHKRDLELFSDHSKEWTEREKQFRDKIQRLQDLLAAAGITDQTAQTQGGRNVGVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ31</accession>
    <name>A0ABR3ZQ31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="777"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="890"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="914" mass="97903" checksum="A4C46DB1C251A0A1" modified="2025-10-08" version="1">MSTEVGVAARPSASLTDDELHLMMEYEKIVKLSESITSGKHPRIKIPTHLAPASSNLPARPDKRSGRNTNTKAASKAAASQGANGTTFEAETPAAHLGDNLVAFGQNSELSVGTAATASLPRLGATSGIRPVSPSVVSLEEIPLQRARVEALLREPSNRRGNVKMDEAQADFMIGDVFVRGRELEKTFTPPPVAILSQDAITNLGGASAKSKANVVSSAAADSGDEQTFYSSNFSTPEFALTSRVLAESDNDDMSMEDGSDYEPELDVIPPPGQTAQQTAQNTVPQPDSTALQQAPADQLAAALSQLSGQAPADFLTSLIAANIDPASLCMPVPPQASVNPTPAQIQQAAVAALSAWPGLAGASQTVGGGNGSSATSVHQRVAAGNPQPSSPFVRTHDLSPVAPQPAHISSLAVASHLPLSIDGQSGSQGTPAQVAMLRQGEASQSSPDNSPYIDGRAADKGKGKKRNVGKRKADVAPSSPYIKPEPRSPSPILAPPAQQRPPKRQKQDARPPPREVVYRRHEDEYSPTMQAAPYGTARVARDPRAPIIYERVDRGGRYVQSRAAAPTRRASVQRYEEQRNLEGGYEQSSPSYAPSYPARPPSRQYAAAPGQPNLRPVRAATHALVETSSGYPAHATADYDGSGRMSVRPLAMAPPPRERIVVDEFGREYYEPVPPAPRPQQQVVETVAYDPNLAYERPASRQHQIRHDARYGSQAPQPVYDDEEVVYRRTSPVFAAPRRVVTQPEYVAREYAGYPRREFSARPPSQYPAAAPERGYMVEEAPPPPGYLARASTARPPDAARYEAPPPGRYVERVGSVRPSGSAVYQGYAGGPEDGQQHMYSGPAGGAYIEDHRGPHEVIREYSVRPEPHVVVHGEYGARPGPAPPYYAEQPQYVMGGPPAPQEYGYPDERGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQB3</accession>
    <name>A0ABR3ZQB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1902008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051801">
        <property type="entry name" value="GH28_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31339">
        <property type="entry name" value="PECTIN LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31339:SF9">
        <property type="entry name" value="PLASMIN AND FIBRONECTIN-BINDING PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045124160" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="420"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="789" mass="82739" checksum="8F8A0ABD7B8D0368" modified="2025-10-08" version="1">MGFSTCLTTALALAASLITPVVAAPAVEYTIAERDAANTSVEAASSSYWLASITRQGTVPFGASGYQIYRNVMDFGAKGDGVTDDTAAINNAISSGGRCGEGCDSSTTSPALVYFPPGKYLVSTPIIQYYYTQLVGDAINPPTLLASAGFTGMAVIDSDPYDSNGNNWWTNQNNFFRQVRNFVIDLTQMPFTAGAGVHWQVAQATSLQNIVFNMRTDGDTANKQVGIFMDNGSGGFMADLVFNGGEYGAFFGNQQFTTRNLTFNNCQTAIFMNWNWAWTLQDVTINNCGVGLDTSNGGSVQTVGSVLFLDSVITNTPIGVKTAYTVSSSATNGTLVIDNVDMTSNVPVAVSDATGSTTVLPGNTKIASWIQGNVPASGGASTAVQGSQTAVNKPSALLDSTGKVFARSRPQYETVPVSDFVSVKSAGAKGDGVTDDTAAIQAVFNSITSSQIVYFDHGNYLVTDTIKVPANARITGEIWPIIMAGGNGTFSDASNTKAVFQVGQAGDSGAVEISDILFATVGPQPGAVMIEWNLKGSSAGAAGIWDSHVRIGGAAGTNLQLSQCAKNPTVTAAADPNCLGAGLMLHVTSGASSLYVENAWFWAADHDLEPSANSAQINIFNGRGVLIESQGPVWMVGTASEHSVLYNYQLSSASNVYMGLIQTETPYFQGNPDARTPYASQAALSDPSFDSCTGATCARAWGLRIANSTDVFVYGAGLYSFFDNYDQTCLDTESCQDNIVSVESSQAYIYGLNTKASVNMATINGVSVALDANNRNNFCATLALVSAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQI4</accession>
    <name>A0ABR3ZQI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit I</fullName>
            <shortName evidence="7">eIF3i</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 39 kDa subunit homolog</fullName>
            <shortName evidence="7">eIF-3 39 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">TIF34</name>
        <name evidence="9" type="ORF">Sste5346_000875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the eIF-3 subunit I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03008">
        <property type="entry name" value="eIF3i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027525">
        <property type="entry name" value="eIF3i"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24805">
        <property type="entry name" value="EIF3I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="284"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="340" mass="37983" checksum="F33F4076A24B8457" modified="2025-10-08" version="1">MRPVLLSGHERALTQVRYNYDGDLIFSVSKDQHICAWYAHNGERLGTYQGHQGAIWTIDVDPTTTILASGSADNTIRLWDAMSGKLLKTWEFPTAVKRVEFNEDATQLLGVTEKRMGHLGTIVVLDIKVDVEAEQSDERAMTIVCDESKATVAGWSYLSKYIIAGHEDGSVSQYDGKTGELIYNVPIHDLNQPITDLQWSPDRTYFITASKDKTAKLVSARDLTVLKTYVADTPLNSACITRKKDFVILGGGQAAMEVTQTAARQGKFEARFYHKIFEDEIGRVRGHFGPLNTVAVDPTGKGYASGGEDGYVRVHQFDKGYFDFLYEVERERANQLALQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR55</accession>
    <name>A0ABR3ZR55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038609">
        <property type="entry name" value="HDA1_su2/3_sf"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
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            <end position="893"/>
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            <begin position="1032"/>
            <end position="1044"/>
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        <location>
            <begin position="1194"/>
            <end position="1203"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1418"/>
            <end position="1431"/>
        </location>
    </feature>
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        <location>
            <begin position="1731"/>
            <end position="1741"/>
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        <location>
            <begin position="1742"/>
            <end position="1751"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1792"/>
            <end position="1808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1903173.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1832" mass="197301" checksum="4F4EA4B995A228F8" modified="2025-10-08" version="1">MDDTSPSAATPTLAPLAPPAVLPAQGPSVSIQNGRDSNSGRSNPPRNSFVPVIPPRSSSILKTASKQKETPAALPASSFTTTRVTRTSARRALAASQTPMPELASSHSPHTTLSSSSIAGPSTQPPLSTNPTKASKATKDPKEKSAKPAKSSKSSKTAKQKAQTPASDAAVDSQEGEWYAIKDIVDEKLVRGVRHYLIDWCNDPVSGKVYEKSWIPARDANKEAIDDWKLVKKALDASRSQVKAKPKSKTAKFAPVENSQSSYAESSNNVLTSQESQAPTVVSAESAASEAPQKAPARSLQRKRPISPSQKENADEDDEDEAEDAGPPPHKRRLVRGIRPDNSRALEPSQNSTSQGGGSQSQDLSQNFSQDLSQDLSQNQSQGPIATSSPPVIHEESVEPAIEQSTQESIQQSVEQDEVFSSQEFSSQEAAPALASNAAIPKTTTTIGTINIAPRPNFNPSDYIRTSQQDHAHLTNISRLALQPHGWMQPQSSVAFQFSPDHLGLLSSNDQQHPSLYHFSQHSNSQDEEVDIEEEDDFVQPLPHSGPTIPDSQPEDSSTLHTATSTNNSQSLFVDQYEDEAPVQAVPQTSQDLIEQPAPSEVTSGIPSQQQQQDEVTESSASRDAQVAPPHLAVPSQDNQQLRASADWASEEEPSAPIIQASANKSAASGSRSETLDFLTQPEPDFVLFTQESQQPSQQQVGKQTSQQTPGPVSSLNADSNNFSAVSVVPDSTRPIRVTTSNPTAAQTAHDDHHHSSSNPLPSSAQIVPPPLHSSSQGRDLIFNSPADFSVPRPSTPSQQPYRAPVALMAESPQPPMSAAQKLRAAMRAQFDEMERNSPAQITLTEDSDPLVEAEMRRMEQEIANEAAAREREQQQMQQQGSSQDESIASSSSNVLPVSAPLVPLADPLLSSTGALDVQPSFIAPQTIDATLPLLISPTALAQSGNIVDGSIGDSGDIHPGTIAPGDLSFVDADPMAASGLDLSPEPEAEFRGGDGDEAADDVDDVDAGEIDQPDAEELDDGPQEPSSPLAMEEDAADDEDDDLLSQAGPNFTTSSYVVTLPLAANTRQYYADLVVEKENERTIKEFSGAFSRDEFVAPSAETVARVDVLLRKLMDFSDLPTYYDSLPPMSKQAMMKHAVDTNSKYSFVHEFLDGISTLENDVLILVRKGVAMDYVEAIVSTAGIPVERYHAPGSTSSATTGSDSEKRRRRSSELSVVLADTTEMSEAMNADVTETDNFPPPNAFDIVIGFDHTARTTELIAYFLGEFSPKSMDDAAAALNNGRIARRQLPKPIVMLLVSAFTLEHIDVRLERNSVDDLERKNALLLCTLECLPQLRDCPPELLPAMPHEAAKAFADIVADPTKVLDWEPTPLPEDVFDIYMHSSGVASQPTFTQEETIDNRLLASRKRQLEDDGDEDGNRGNDTPKRMRLTETSTPIIRAVPNRFNDIIKYSLGRLDVAASSNDPVVEISLAQLEALASKVTYLESVLEEKEGIEAKQTDRLRTLDRHVKSQAATINDCQRRLVEAVNERGTFEKNHAIAVKEATATKEKLDACTASLAEVRTEKTTLETQLAGANALLAGSKQPDVAELGSARVALKEAQEKLAVLERKTSSADSDLTYARKAYQDASNSAIETSNENRTLKARIKELERLANDNLRSIHETNARDEAENYRRQWDEANTMLLERERELEWLREELRVLKNGRRETRQQSVPRSPRLSVISPRTVGRGSSVGVGNGGGASSSASVTPAPNLAPNMGGPPGAGYAVAARQSVSRGNSPVSANFDPSVYGGMSSGGNSGNGGNGGAAGGPPLPGMTYLNSGQGSGRWGHLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRF5</accession>
    <name>A0ABR3ZRF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="SCP-like"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="18"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="125" mass="13545" checksum="51588AB604FD7472" modified="2025-10-08" version="1">MGISNDKFPSSVAFDAINDVLNNSEADRKDAIKNGKAVFGITLKNKAGDTESWFIDLAKEGKVVQGLDKSDVELRLSDEDFGKLVMGKAKAQGLFMSGKLKIKGNVMKAAKLEPILNKSRSKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRH0</accession>
    <name>A0ABR3ZRH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">U3 small nucleolar RNA-associated protein 25</fullName>
            <shortName evidence="10">U3 snoRNA-associated protein 25</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">UTP25</name>
        <name evidence="14" type="ORF">Sste5346_000541</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
            <location evidence="2 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the UTP25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 10" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="13">
        <location>
            <begin position="294"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 C-terminal" evidence="12">
        <location>
            <begin position="597"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1903256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="799" mass="89777" checksum="3CF9A0D16BA5FF5A" modified="2025-10-08" version="1">MGPGPKFRGRGGPRGGGSRGGPRGGGARGGSMRGGDRGGRGGRGRGRGRGARGRGRAARFDSSRLAAQDAEEQDSEPESPSEDEVESEVEESDEESESEKKKEAYRALMQSFESRSAAAPAAKRRKLENGAVAEPVEDDSEEEEDEDEEEEESGSDDGEDEEVEGEEGKAKDVDYMDEDDDDADEDLDLDDDDDDDEQVGTTDPFESHYSAPDLKNIELRLEAIQGDNWATSKAKVNDTRQVFTLPKTEAADSFTAPAPVKNPQQLNLKKRLADINKAPFSHDQQTVAPLLFNYYDTLFTERSPQNGDALRKLASLHAVNHVFKTRDRVLKNNEKLAKIARKKQESGAAEDDEDYDENDEYRDQGYNRPKVLILLPTRQSCARMVDAICSVYQPEQQENRKRFDDTYVDKSSTIPEDRPADFRDLFEGNDDDMFRLGLKFTRKTVKYFSQFYNSDIILASPLGLRIAMGSEDTLATSLAESKRKGKPKTDFDFLSSIEVVLLDQADALLMQNWEHVEHIFSHLNLLPRDNNEYDISRLRSWYLDDRAKYYRQTVVFSSVHTPALSELFRRFCHNWAGRVRVQAGEYKGVVGRIGMRGVKQTFSRFESPTIEAEPDARFDYFTKAVVPTLIAKTRTGSGSTAANRSTGVLVFIPSYLDFVRVRNWFATSVAVANVTFGAISEYASVPEASRAMSHFLTGRHRVLLYSERAHHFRRNQINGVRTVILYGLPENPTFYTEITGGFLARSQRSQKLEPGQGTVRVMFSQFDAFKLERIVGSASVGQMLRERSDTFVFEEDKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRK7</accession>
    <name>A0ABR3ZRK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001158</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="677"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="789"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="685"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="800"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="816"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="978" mass="106431" checksum="174E656361ACF3F2" modified="2025-10-08" version="1">MEDDRDFSMLLDDNDFSDSPGSGGGGSGGNVTAAGNRSGAAASAARATATGENALPKRTRVLLSCAPCRISKLKCDRESPCGNCLKKDRIDLCEYAPRPKKPVKPAKGMAARLRRLEGMLREMMDDDTAAAAMSSFGVSSAELLANGGNGSKNGGNEGQPSLMSILTEAEAEGYDGTGKPIPTSATTSAAVDGNGATAATQNPTPQARGKGRVVRGQRATTYVGATHFMAMLDDIEDLKAYFEDPQNVPEDEWQDVSPSAGDSPEQLMLGGQQPRSRVELLAVMPPRPIVDRLIVRYFGSNTPTQHTVHRPSFSRKYKEFWQDPVNADVDFLAVLFIILALGVHFSTFSAPHELELDGTGMTPAERYRVYRGAASAALSLTRFSNPNLHTIRALLMFAESEFLVNRATQTNCFLLLAVCIRLMLKMGLHRDPSRLPTISAFEGEIRRRLWNLAIQIDLIVSFYLGLPSMIHGIPSDTSLAHNLLDEDFNEDSPVLPPPRPDSEYTVMSYPIFKSMVCRIFGQVARLAHTLTPPKYAEVLRTDRLLEDKWRQIPDFMKVRPLGDCVADPPMQVVQRFGLASLYQKSRCVLHRPYLVEAVPLPEHAYSRKTCLQSALTLLAYHEAIHEATQPGGLLYHIGWFITGLGMHDFLLAAMIVYLVVQNDNLFESELLTSRDGVNRNHKGSVDATATTATPSTGPATVGSGTSTTTASTAASTSASATSGSTDPTAPSTDYDTPPSLPVERNSLIDLLRRSHRIWADVAEKNSDTIKAADLLSVMLRKIYARELRENGSPPDWAPPPDHRQEAQRQQQKDRSTSSQWSSSQPLSHAPQPQPSQSSQSSQSMHSHVDPGVVGGIPPLSETTLRSLGLQETMMPQAHPLVRPPLDITPNDAPMGFSRRDLVPPSQLPAGATNNMAAPSRYDSWIPLSLDALDWGSVDNGIRVINSQDTSEWTGADSVINDINYAAAGMWDQPDQAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRL4</accession>
    <name>A0ABR3ZRL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Phospholipase C type enzyme</fullName>
            <ecNumber evidence="15">3.1.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ISC1</name>
        <name evidence="15" type="ORF">Sste5346_000745</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF24">
        <property type="entry name" value="PHOSPHODIESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="443"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="14">
        <location>
            <begin position="10"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="503" mass="55186" checksum="1765E4EA95CD5BF0" modified="2025-10-08" version="1">MADLFEISALTLNCWGLKYISALRTDRLAEIGRRIAVLASSSSSPSTTPLSIVALQECWCYEDFAAIHELTRHELPYAKFFHAGVWGAGLAVLSRWPITSTSMTPYALNGRPTAFWRGDWFVGKGLASATVKVDDATTLEVLVTHTHAPYEGGQPDDSYLLHQVAQTWEAGKRIRAAAERGRLVLAMGDWNMTPDSLPYQSLYLGAGSSGDASSPFVLHDTWRDLHPNAALGNSYNPLEQARQQRHNPQGQQTVPTAAFNLAENGTASDNVLNTWRWPKDKQKRLQKAYARRQTAASAGEDIASEFVIAPDTPDPRAKRLDYIFYAAPCPPAVSTPPASLWRTKTARVAMVEPHPTLGCSVSDHYAVAVTLVREPASAGTIQVDTAGVPTVLPSTFNNVLAELDRYMAREQSQRYWRGVHFFVSVAVTIGCYVAVWFSPRNFVAFLLTLLASLGLATGVVDGLIALLFFGSEIRYIKDFQWEIDNAKAAASSVRAPSSHVEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRP3</accession>
    <name>A0ABR3ZRP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">PKC1_2</name>
        <name evidence="23" type="ORF">Sste5346_001454</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08689">
        <property type="entry name" value="C2_fungal_Pkc1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11620">
        <property type="entry name" value="HR1_PKC-like_2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037778">
        <property type="entry name" value="C2_fungal_PKC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037312">
        <property type="entry name" value="PKC-like_HR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 23" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="22">
        <location>
            <begin position="165"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="18">
        <location>
            <begin position="248"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="483"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="551"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="872"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="21">
        <location>
            <begin position="1132"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="73"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="376"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="617"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="390"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="652"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="770"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="822"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="901"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAL1902473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1197" mass="133054" checksum="10DE0598E68A02B8" modified="2025-10-08" version="1">MADDQQMQTILKKIDIEKVFLGKAIEMRKAANSDNADVLSKLDSAVHSARRHLEYYEDMLRQVQVRRLGQGVDNMSLGSAGSPNSPASGSLRPRSTDLRNEAGPPPTPPPKDSSSTWSDSATLNSQNYPSNTYAQGGLQSPSSYSPADTALVKTRPNYTKLDLIKYDTPYMGPRIQHMLSQIQFKLDVEEQYLKGIEKMVQLYQMEGDKKSKADAASKKVESKQKIVLLKQALKRYEELHIDIDSGDTPDDDSVNVPNMRKPLSGNLSIRIMAVKDVDHAPTGRFSRGPDTFVAVKVEDNVAARTRLSRTDRWESEFHSVDVDKANEIELTVYDKPGEYAIPIGMLWVRISDIAEEIRRKRIEAEINSSGWVSADKMSAAPNRAPPAQFPMNNQGQFGAQQNPQGGPLSPQHPQGGGFDGVGAHAAHLSPEPITGWFNLEPTGQIQLNLNFVRQNKDRRPLDLGLGRKGAIRQKKEEVHEMYGHKFVQRQFYNIMRCALCGDFLKGGAGMQCEDCKYTCHIKCYSSVVTKCISKSNAETDPDEEKINHRIPHRFQAFGNYTANWCCHCGYLLPFGKKSCRKCSECGLTAHAGCAHLVPDFCGMSMAVANQILEGIRTQKQRQKQTTNLSDRTLRPGKPNLSSQPGGYGAQGAGPAPYGPGAASAQATEAAKVMYANQQQTSPQRPQHPDRTSSASSSAAAAAASMAMSSMSSGAKAGTGPQTPAGGDSWRHDPGNYGDPYGAPQQVQAQQQQYGNAPQQRKYNPADYINVGQYPPSQQQPGQMQHAQQQQSPVAIQQQQQQQQMYQQQPQQQPLQQQPPQPQVQVKPQQIEPPVSLSPVTSTAVDITGPGGKKPLPSATDPGTGQRIGLDNFNFLAVLGKGNFGKVMLAETKRSNKLYAIKVLKKEFIIENDEVESIRSEKRVLLVANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRGQFGTRRAQFYAAEVCLALKYLHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILGDEPLYPIHMPRDSVSILQKLLTRDPDQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFLPTIKNPTDTSNFDSEFTSVTPVLTPVQSVLSQAMQEEFRGFSYTADFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRV9</accession>
    <name>A0ABR3ZRV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF3">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="16"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="379" mass="39992" checksum="01F70E84929474E7" modified="2025-10-08" version="1">MPLSLIVQKVDGKPGQVNYPLKLKEVPKPTPGPGELLVRIRAAALNHRDVFIRQNLYPGISFENPLFADGCGVVEVVGSGCKRSEVAQVGAAVVMAPCRNWTSDPDGPEEYNKFSALGGAVGVDAGTGTEYLSVPEDELELAPAHLSASEVAALPLVGLTAWRALVTKSNAVSTAQPAGGRNVLVTGIGGGVAIAATQLAIAHGCRVYVTSGDPAKLQRAANELGVAGGVNYKDADWDKQLLKLLPKERPQFDAIIDGAGGDIIKRAVRLLRPGGVVSSYGMTVSPKMDWLMSAVLRNIELKGSTMGSRAEFRAMVAFVRQHKIRPIVSRVVYGGLSEANLPAIDGLFDDIKAGRQFGKVVLSFEEEGSSSGRDSPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRX1</accession>
    <name>A0ABR3ZRX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EFT2</name>
        <name evidence="10" type="ORF">Sste5346_000990</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="17"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="844" mass="93716" checksum="0F429B6CD71A51FD" modified="2025-10-08" version="1">MVNFTIDEIRQLMDKPTNVRNMSVIAHVDHGKSTLTDSLLAKAGIISTAKAGDARATDTRADEQERGITIKSTAISLYGTLAEDDDIKDIVGQKTDGNNFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTVEGVCVQTETVLRQALGERIRPVIIINKVDRALLELQVSKEDLYQSFSRTIESVNVIISTYLDDALGDVQVYPDRGTVAFGSGLHGWAFTIRQFAVRYAKKFGVDRNKMMERLWGDNYFNPATKKWTKNGTYEGKQLERAFNQFILDPIFKIFAAVMNFRKEEITTLLEKLSLKLSVDDREKEGKQLLKAVMRTFLPAADSLLEMMILHLPSPVTAQRYRVETLYEGPMDDEAAIGIRDCDPKAPLMLYVSKMVPTSDKGRFYAFGRVFSGTVRSGLRVRIQGPNYVPGKKEDLTIKAIQRTVLMMGGKVEPIDDMPAGNIVGLVGIDQFLLKSGTLSTSETSHNLKVMKFSVSPVVQRSVQVKNAQDLPKLVEGLKRLSKSDPCVLTLTNESGEHVVAGAGELHLEICLKDLEEDHAGVPLIISDPVVQFRETVTAKSSMTALSKSPNKHNRLYMEAEPLDEELAKEIEAGKIGPRDDFKARGRVLADNYGWDVTDARKIWAFGPDTIGANLLVDQTKAVQYLQEIKDSVVSGFQWATREGPIGEEPMRQIRFNIMDVTLHADAIHRGGGQIISTARRVLFASLLLAEPALLEPVFLVEIQVPEQAMGGVYGVLTRRRGHVFNEEQRPGTPLFTIKAYMPVMESFGFNGDLRQATGGQAFPQSVFDHYQLLPGGSPLDPTSKVGQIVLDMRKRKNIKVELPTYDMYYDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSJ2</accession>
    <name>A0ABR3ZSJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_000292</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968673" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="296" mass="31893" checksum="AE79AF21BE7F92DB" modified="2025-10-08" version="1">MLLQALLGGVFLAAQVQLAQAAELKQVDYPNNATSKVQMFVYVPDNVVPNPPLVVVIHSCQSTAQTYFRNSKIPWKQGSDKKGYITVWPSSPHSGTCWDVSSKATLTHNGGGDSQAIANMILYSIDKYKVDPAKVFVTGGSSGAMMSNVMAATYPELISAVSLYSGVAAGCFVSSSGGVDQWNNSCSGGQAKATAEKWGDVARAMYPDYSGPRPRMQIWHGSADSTLAPGNYQEEIKQWTNVFNVPQTPTDTRKNYPQANYQTDDYGDHVEGIYATGVGHSVPSNLTASEIWFGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSM3</accession>
    <name>A0ABR3ZSM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M56 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="44380" checksum="F7633C72F9A3E1C9" modified="2025-10-08" version="1">MKTTNRTWRLPCLRLKVGDVILSKTTQVKGHEWTLRWKENTVLDDVGHWASSEVRIVRISEGYTHEFVELRVRKFVPQDGDSLERSWVAPNGETRSVQIPPYAVIEPEAIAPQYSAYIKRGLVTCCKNVLADKKDTILWPTYWVALNLTRESSHNLSEKELKLLTKTLDLWMTVRLTTRSFEIVGNETLDMPPNILDETSPSHGKIPIPPVMGAQLDSVLIHEIQHTLRHDVLQALQDMIGANKTSYWFTLYLVMFILLHNAALVIKHDASYARKHGLKRRFAREDKVQQYYTGAITLLAYFHYCNKGVFPFTESAREQDVRNLANIDDHTMGFVKYTRQYAIDNKARWQDMRDRNDYEDEFYFISQLYEVNWQPRKMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT00</accession>
    <name>A0ABR3ZT00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Post-SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053201">
        <property type="entry name" value="Flavunoidine_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350:SF19">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Post-SET" evidence="4">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="206"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="276" mass="29593" checksum="FD06C0ACE968BDDA" modified="2025-10-08" version="1">MSAPLKPHWVQPSHPEIQEVLIGSNGDSEFTTKSISRVDLPPFALYAPMSSPPVTPAAAATYATVQVGRNQHINLNSDLLYINHSCEPSLLFDTSSRNVWVGPKGLKAGEELTFFYPSTEWDMAQPFTCFCGTPTCRGLISGARNMTQDQLAGLWLNGHIWELLNEQKQQQSKTARPENGTSSTAATTAEIPSAIEQALKEELARAEESLHKADQATENARRALAAHRSGVTTNGKAPSSNGTNGVTKAIPNGAARHGTSSRELGGELGGDTAERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT74</accession>
    <name>A0ABR3ZT74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04090">
        <property type="entry name" value="EF2_II_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01683">
        <property type="entry name" value="EF2_IV_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16264">
        <property type="entry name" value="snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04167">
        <property type="entry name" value="Snu114p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031950">
        <property type="entry name" value="EFTUD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044121">
        <property type="entry name" value="Snu114_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF6">
        <property type="entry name" value="116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16004">
        <property type="entry name" value="EFTUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="132"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="988" mass="110399" checksum="5D8EE2717D9FA4E1" modified="2025-10-08" version="1">MDDLYDEFGNFIGEEPEASEEGSEQGDADADNYVYGDEEEVDEDGMGQELMEVDDEGPSNAVILHEDKQYYPTAAQVYGTEVEALVQEEDAQPLSEPIVAPVEQKKFAVEEADLPPVFFDRSFMTDLMNFPEQIRNVAFAGHLHHGKTAFVDMLVLETHDISDRLEQRTGKNRDEQLRYTDVHVLERERGVSIRSAPMSLVLPSTKGKSHLINLIDTPGHVDFADEVASALRLVDGVCLVVDVIEGVQLHTEMVIRHAMLEDIPLTLIVNKVDRLILELKLPPTDAYYKLKSTIEAVNKVIFETLPGETDDSKRVSPEKGNVLFACTEMKWCFTLPSFTKMYADSFGAMDTDEFAKRLWGDIFFNPKKRSFTRKAVEDNAKRSFVHFVLEPIYKLFTHTISENPQDLKAFLTPLGISLKPSQYKADAKVLLGLVCAQFFGPPAAFVDMIVKHIPSPVEASTRHLQRYYTGPLDTKVAESIGACDQDGPLVMEVTKLYSSTDAKSFHALGRVLSGIARPGTEVRVLGEGYSLDDEEDMAPALISNVWIPETRYNVPVDGVPAGNWVLLGGVDNSIVKSATVVARQFEDDEDAYIFKPVTHYTESVFKIAVEPVNPSELPKMLDGIRKINKSYPLITTKVEESGEHILIGTGEMYMDCVMHDLRLQYADMEIKVSDPLTRFCETVVDESATRCWTLTPNKKNRLTMVAEPLEDGLARDIESGAVRIKDPVRKTAKFFQDKYDWDLLASRSVWAFGPEEMGANLLQDDTLPGEVDKKLLNTVKESIRQGFSWATREGPLCEEPIRNIKFKLTDVTLAQETIYRGGGQIIPTARRACYGSFMLSSPRLMEPVYTVSMTGPESASSKLYQILSQRRGHVLTDVGIPGTNLSRTVGLLPVIDSFGFETDFRISSDNKGLVSLVFDRWQVVPGDPLDRDVILRPMQMAPVQGTARDFVLKTRRRKGLSEDVSIGKFLEPELYSELVSSGTLEEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUW0</accession>
    <name>A0ABR3ZUW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exosome non-catalytic core subunit rrp46</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRP46</name>
        <name evidence="7" type="ORF">Sste5346_000393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11372">
        <property type="entry name" value="RNase_PH_RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="14"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="27881" checksum="8A16EFAA7280217D" modified="2025-10-08" version="1">MAAVAEPLAVLSPLPRADGSATYSHAGYTITASANGPIEAQRRDEDPDEATVDVVVRPAAGVGGPSERHLESVLQKTLQEIILVQDFPRCLIQVVLQVQSVPENDYVNTRLNTPGLNLGVLPALLQSAVLALLSASIPMRTTATAVSLAILPVSSDSTDTKIVSSFSPRDASIAKSTHAFAFLAQSDKLLLAESAGEFSMGEWDDVLAVAKNICCQTAETVDASGDGMALDSNGNTDGPDLRGFLRSTVQGKLEDALKWKAAPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZWC0</accession>
    <name>A0ABR3ZWC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">rmt3</name>
        <name evidence="17" type="ORF">Sste5346_000317</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:48097"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049482">
        <property type="entry name" value="ANM3-like_C2H2_Zf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF116">
        <property type="entry name" value="PROTEIN METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21137">
        <property type="entry name" value="ANM3_C2H2_Zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 17" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="17" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase 3-like C2H2 zinc finger" evidence="15">
        <location>
            <begin position="64"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="16">
        <location>
            <begin position="366"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="181"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1903688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="62351" checksum="ADF5A765B4FB9D9F" modified="2025-10-08" version="1">MSERDFHSSSESSDDEGWLDANPEDDEEPQTVISLLDDHVFPDAASMIAYCKEEHGFDFLAVRDRLGLDFYGSVKLINFIRQRVHNKSALPAEISSADISGDEYLKPVLEDDALIFALDSLPEPRAQPDASEDKGTAAADAAGATDLQKQNEQLQAELEGLTKQFENYRLAVQKTLDQRWGVDEDSQKSAKDTKPASVPNDTKAVSSSEKSGEEVPASGGTDYYFESYSHSDIHETMLKDTIRTDAYRDFIYANKNLFTGKTVLDIGCGTGILSMFCAKAGAKLVIAVDRSEIINKARENIFHNGLAGQITCLKGLIEEVTLPVDKVDIIVSEWMGYALLYEAMLPSVLYARDKYLKADGLLVPSHASLFLAPVSDSEYICDSITFWRDVYGFDMKAMQAGIYDDARMLVMPEKTIAGTTSMFKHLDLHTIKVEDLVFTANWKSVLSKDAESLDGFLVWFDIYFGTSRTSQIEPVDASSQAWVAAGKDRVAFTTGPFDKATHWMQCLLLDKAHSKALTETDVREVDGELSFITADDNPRALTLQVKWTRGTTEQKQSWALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFH3</accession>
    <name>A0ABR3YFH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phospholipid:diacylglycerol acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.158</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LRO1</name>
        <name evidence="1" type="ORF">Sste5346_010466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.158" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000154">
        <property type="protein sequence ID" value="KAL1887048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046027">
        <property type="term" value="F:phospholipid:diacylglycerol acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="59793" checksum="C39953CAD814A5EE" modified="2025-10-08" version="1">MSMAGLVTDMRDLVNGERDLLDSSDAFSVGLKVKADGLGVNHSVIMIPGVISTGLESWGTANASRQYFRKRLWGSWSMMRALVLDKENWKRHIMLDEKTGLDPPGYRMRAAQGFDATDFFITGYWIWNKIFENLASLGYDPTNSFTAAYDWRLSYANLEVRDQYFTRLKMYIEMAATTSDRKVVLVSHSMGSQVLFYFFHWVASPLGGRGGDGWVEKYVDSWINVSGCMLGAVKDLTAVLSGEMRDTAQLNSFAVYGLEKFLSKEERADIFRAMPGISSMLPIGGDAVWGSIEDGAPDDLPGQEQSFAALLNFRKGENWTTPLQNLTVSGALDYLFNTSQAWYREQIWSSYSHGVAQTSAEVNENEKDPRKWINPLETRLPLAPSLKIYCFYGVGKPTERSYYYRSPDPLPPTKLNITIDTTLTQGEMIDHGVVMGEGDGTVNLLSTGYMCNQGWKFRRFNPAGAKITVVEMPHEPERFNPRGGPNTADHVDILGRQTLNELILKVAAGHGEAIEERVVSGIRQYAAKVKIFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGI7</accession>
    <name>A0ABR3YGI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DDENN domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010281</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000126">
        <property type="protein sequence ID" value="KAL1887342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005112">
        <property type="entry name" value="dDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF21">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03455">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00801">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="UDENN" evidence="5">
        <location>
            <begin position="245"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="880"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="738"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="745"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="785"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1148" mass="127306" checksum="F6311A7A9DA87F98" modified="2025-10-08" version="1">MDSSASTPLADYFWIAGVESISYQDPPQAPQPPQQVEETIDEHGEPELAEASRSPVAYRANNRHSRQSSGNRLSKLSLENRFSIQTLDDLDDSTRSNRSSTTIKAPLQPTISASSTATATLESSSNGDAGAGASGAASRADFDFDQMLVKFAAERENFLEDLSFSAGAKLHSRPPMISPRAEKIKAEDSELSGRRSPLRSIKGSIRRKLSFRDMNSVRKPHNTARTASVRTSKRLSNYNSVIPPPEPLNSDPDMHPLKRRFEPVLLDRYPPRSATEEILRRGKFPDYVPMFAFPNDIQIVSSDDRPRSTWHGFTMTSDDNSKVYGICITIWTVLKADTAEEVEKRCEQWRQSHMSDEERELAASLGMRLAAERANLSQLLAKLPGVPSGSPAREVLDDQISTVEEKISLMAEMLRPLRHGAASKIDGLTSGETGLWVPRAYGILGRDPTRMAFWKEWLRAVIVPMTDGAVLRIPPSSPKVGRWQPLERYVVNLCTEAFSPLSSKTQVELGVRELRLYARKEAANELPGSRNVDLFALFRCLSLENIVTLFEYVMVESRIIFLSSHSAMLYLACHAIANLLYPLKWASIFIPLLPARLLSVVEAPCPYIVGIERRYENIDLPEDDFVLVDLDKDTIEATSPPTHMPRQHRRKLLSLLQMAAPHRLRYGVPPGPPPYAMETFPYDSFSAENESLLNPIAPPATLGKWVTQNSTSFGEQDSPGSVRVPIFNAFVQLRNEFARADRPQTARSSKTSPPASLSPISTSFPQMPSTPVSRSDSGFAVTQTLREKRSGHFDEKSRRSSSFGVADRNHPLHRPSLQYLNGHSHTQSMSISAVSVDSQSSYGGYAPSTYAQSTLAASTVMPNMVVQPVSNTDTTMWVEGHCFTWSREDASGTCGICEERSDGDGLYRCAGCKCLAHNRCLGFASLVCPEAFSADKVRAAFVRCLASIFYTYRKHLGRPTREQKSNGQVFAFDIGGFIKSLPYDQQEYVSTLRNTQAFNEFIYERERHPPGHSSTRLFDEIILAKKARGRPVLGGFSGLSRLSTIKASHGISSGMSSASKQTRIPPYLGDTSDHIWRTASVPVPSAKFPGEYRAVTTRVPSKLDPSLMKEPRAIQGVPRPEQRGSRNLIRKQVASMLGPPAPTNNDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL7</accession>
    <name>A0ABR3YHL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000127">
        <property type="protein sequence ID" value="KAL1887332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="227" mass="24429" checksum="68E3111300F0ED04" modified="2025-10-08" version="1">MHTLASSMPRLFGRSQTPTPSQSQPQEPPAPRAKLVRRTGDHFTPLGHPGHPGHTGYSGYQSPASFEPLHREGSIISASLASASASGYEVLLNGPDRSSLCGSIGSGQNQHHPTQNQQHQQHRYYAVRSQRNLHRSWLAAADARRLSGPGGERPPPRKLVKDPGGSARPSAAHEIPDEDGDLRRKAVVGGAGQNNSQSTAGLDRGSFGGPGSLGIRRKISRWRDLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHP4</accession>
    <name>A0ABR3YHP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arylsulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734957" description="Arylsulfotransferase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="587"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="672" mass="73150" checksum="0B6C05B237C859C7" modified="2025-10-08" version="1">MTRLPLFSSMLSSALLTVLSTALFARPAAADTPFNTDLNAYQEGALGTEPNQTFYSAPLVVGPVYQINTFDPKKIDASTDSAYMFMAGKFPGVDWGPSIVSSKDLSLVWADQHYHGLAQATNTYMFRGERVLVVFVDDAVRIISQEYQELYAVKPVGNFSHWHPDSHEAGLTADDTVLTIVCPNWETDMTAVGGPDNGIVANCLVQEIDPTNNELLFEWTTLDFFNVTDSVWDYHGEGVWDFAHMNSVEKTPDGNFLISYRHLSAIVLVDGKTNEVIWVMGGKRNMFTDITKQRTGRDRSARFGWQHNPRLTGTNRFTFFDNHRLDNGYCWPGSGVCSRGLEIEFDPVAKTVWLLDEWPHPQGLVSASRGSTQRTSAGNVLIAWGQNPGFVEYTASGDLAMDIQRGQILTIDHGIEPIVAYRVAKGPWVGKPTWGPNISCVTTASESSEAKTKKTVYVSWNGATEVDNYVLLSADNLDKLDSADAVVAQSPRNGFETAFSVVGYTLKKYARVAALDVHGVILGSTPAVDTTTGALTDLDYAVTSVFAAGAKSVTGVPLSVSAVVPAGTHATKPPSVVSRPLSKDRKISIILGSVGAAVVVLAGLAVVAFKWYVRRRARQQIEAASEQQVRRQERGDDEAGEGLLAAADEYGLDSFAPRNSTDSEGSEAYKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHR7</accession>
    <name>A0ABR3YHR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Modin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="712" mass="78752" checksum="A41B63FD3A11E5DC" modified="2025-10-08" version="1">MSSNQTGDNSTSNNNSSNGNGNDSSDTIIAIVALVVSVIALVGTGLQVVQQYLASAAGYSNCDAAVIGPWHTTKKRRFRLSEMRFQVLFETPVFFVCPADNTRGPIKDAPVWFVKGNPESIAITRSLPLDGPDPNSSAGKPSQRPDGAQNDAAAHTSHASHAAHAAHAALTASKPQDKRGVHTADNEMSTWVRLLQELQRMERDSQHWQKTQVELNPPHSACTFEEHKLCVALQAKKRSWDTMPSSISRPYAASTICHLVEMAAMLGIYWKEFDRSTGRYRAEGNGYVLTGSHMADLGIVFTFQICGKSRFKENRIIPADEAKELAFGLVPTIFRRKEDLRRLAFTTDDTRTLETLLLGNRNELAETLASIGCNTNTSNSLRDENKKHGHLFPLAFEITGMLGRTLHIKKSLFRFLPNPTFYHWDRKYFSMRKLLQEYRTEISCLVTDEPQIKELQTLASTIADLLLRKPERNGASRAKRPPEDAIDRPLMNILHENLDRCDLFLKKKGRKAVELVLREHVQELLRMVNNEGEYGSTTNVAGGTAGAGAGAGAAAEPSGSGAGRNGESSPLGATSKDESKFGVPLRFDDVMTASPEVRQRTLMRIYFSRLQPRVVKLAEEAWLRQQDDGNSDDEDADVEVGNGNNEDSGDNGDNDDGGHGGGNRPGRLEAASVWCTLVFRMLCWLLLHDFSKMDVQISKSELLGNRLPVYIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHS6</accession>
    <name>A0ABR3YHS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proteinase B</fullName>
            <ecNumber evidence="10">3.4.21.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRB1</name>
        <name evidence="10" type="ORF">Sste5346_009931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.48" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000106">
        <property type="protein sequence ID" value="KAL1887873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046813322" evidence="7">
        <location>
            <begin position="16"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="44"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="200"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="550" mass="58575" checksum="D9926D9BC314ED28" modified="2025-10-08" version="1">MKGLIALSLVAVASAAPAFNTETIHGDAAPILSSANAEEVPGAYIIKFKDHVDEKAAEDHHSWVKNIHDTWVKTFPENKDERILELRKRGFGLSLADEVFKGLKHTYKIGSGFVGYAGHFDDSVIEQVRRHPDVEYIHRDTVVHTMKYQEIEVTKSCSPETEKGAPWGLARVSHRKSLNFGTFNKYLYAEEGGEGVDAYVIDTGTNVNHVDFDGRAHWGKTIPQGDEDVDGNGHGTHCSGTIAGKKYGVAKKANVYAVKVLKSNGSGTMSDVIAGVEFAAQRHIEQVAAAKKGKRKGFKGSVANMSLGGGKTTPLDAAVNAAVNAGLHFAVAAGNDNADACNYSPAAAANAVTVGASAIDDSRAYFSNYGKCTDVFAPGLNIQSTWIGSNTAINTISGTSMASPHVCGLLAYYLSLQPDTDSEYSVAPITPAKLKSNLLAVSTVGTLTDIPADTPNLLIWNGGGCSNYTAIVEEGAYDAAADKVAEKSATDVVLDSVTELEKAIEADFEVVSGKVVGGASAFGRKAHKFSEKIHELVDEELKEFFEELKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI18</accession>
    <name>A0ABR3YI18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000112">
        <property type="protein sequence ID" value="KAL1887660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16025">
        <property type="entry name" value="PAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF33">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="617" mass="68018" checksum="246FE0DF950C1717" modified="2025-10-08" version="1">MAGSRPNFLFILADDLGFSDIGCYGAEIETPNIDKLAAAGLRLVNHHTAAACSPTRAMLMSGTDAHLGGLGVLIEFKGNEKGAARYGGKAGYEGYLNQDVAALPEILSDNGYYTVMSGKWHLGMRSSQGPWNRGFQKAFAMLPGCCNHYGWEPVQEKFPVGGRPIHAEAGKKVDIKPNTTEDPEGFYSTDYYTSQLLNFFEERTSEEKEKPFFAFLPYTAPHWPLQCSKAQRNKYKNKYDEGPHALREKRLKRLVELGIIDASVKPHKVETSAVGASEWDSLTDEEKKLSCRAMETYAGMVDSVDVNVGRVVDYLKRTGEYDNTFIVFMSDNGAEGASLEAIPVMGTNIKQSIHKYYDNSHENIGAWNSYSWLGPLWAQASTAPSRLYKCFPSEGGILVPCVVKPPVSTFSSNFQPGALNRSFSTIMDFAPTFLELAGVSLPPAVDRVMPTPLGGGTATRKMTTFRGRDVHAMRGQSWLPYFSSSSPFSAADQTWAIHSESEAVGWELFARGALRKGDWKIVHIDQRNGGAGVGDEGWELFNVAEDPGETHDCATDEPEKFKELLAHWDEYVVECGIVWGDTAAAAGRTRDEAPELWDDDTELQRTWMGARGGETPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIB3</accession>
    <name>A0ABR3YIB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11 13">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ubp14</name>
        <name evidence="18" type="ORF">Sste5346_009803</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20 21 22">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 13">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11 13"/>
    <dbReference type="EMBL" id="JAWCUI010000101">
        <property type="protein sequence ID" value="KAL1888066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11 13" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 11 13" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11 13" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="17">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="17">
        <location>
            <begin position="150"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="16">
        <location>
            <begin position="301"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="587"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="654"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="697"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1888066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="791" mass="86646" checksum="882311952392ADAF" modified="2025-10-08" version="1">MACPHLASISLRPPTPAQSVYREDCTECFDSIDDPEGLDVCLQCFNGGCTGDRNHAKIHNISFQHPLALNIRRTRKAIVRDEPPPKMSKLAIAAETEEDRYDTKVAVKCLECDTELDTTDPKLAPIVDGILKANTFSRKEEVKAWEQELVSCEHVRSLYQDAARTIASQDLGHCSSCELNENLWLCLQCGNLGCGRAQFGGVGGNSHGLAHATETGHGVAVKLGSITPEGNADVYCYTCDDERIDDKLGDHLAHWGIILAERQKTEKSLTEMQIEQNLRWEFTMTTEDGKELRPLFGKGLTGLKNLGNSCYLASILQCLYDLPSFQKRYGRISQDMVGLRDPADDLETQLRKVGDGLLSGRYSKPDADVSVRTGDDPVVPHQKGLEPAMLKHLVGRGHEEFSTMRQQDAFELLQHLIKLITRAKHATPADDPTVPFRFTLEQRLQCLSCKKVRYTTNEQDSIFIDVPLEKLPAEEGSDAADAGYKPVTLKECLDRFTGEETVELTCAACGSKDGYSKRSLFKTLPDVFVVNARKMTLVNWVPIKVDVPVLVDDAAFPLDEYLSPGQQPNEELLPEDSAAATGAPAFVANPEAVAQLEGMGFPLVRCEKALYATGNSDANAAMEWLFGHMEDPDIDEPLVIESGGGGAGGAGAAAADPEKIEMLGAMGFAEPQAKQALRETGGDVERAVEWLFSHPDATGEDESAAAGADASSAERPPAGTSDTPANYQLQSIVCHKGTSIHAGHYVAFIRKKLAEDSDKVSWVLFNDEKVVEVVDVEEMKKFAYIYFFKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIE4</accession>
    <name>A0ABR3YIE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009783</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF32">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="670"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="674"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="714"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="791" mass="89140" checksum="2EAEF8C1B67AA22A" modified="2025-10-08" version="1">MRLCLRLKKDCQPAVGARRKPGRKPAASKTDELEARLNGLMSLLENVPGLNQQQQQQQKQQEQSGSRAGSTPGSSSATAVSSGSTIVPRSSVFFADRQITYSPHEICIGGSQQPMEVDDTDNTPASSSRPQQQHEEPSRTDSHGRPSKKMFDGGGHIPCPVPFDAEEALERFRTRNVKFFPFVHVPPFMSAARLQQTRPLLWLSIMACSARSAEIQTRLCLRLREQIAEQAIVQHQRSVDLLLGIVGFLGWGMYYLKRDPFMLMYCHMATAMVQDLGLDREPPMPRPPAHSAAASEQHPLSTIRMHGFAIKLLESPVRTNEERRAVLGAYLVTVIVTLFHRKPITLPWTDHMNECLCVLDTDPETPLDRLLVYQCRLQRVALDIPGPQAYISITSAAQMRQTRDFQVKSLLARQREAEQMCPPNLPADLLEICRMSNLANEASIYSIALFNTNQSAEERLRHGPDTKRAELLNTCLRLHKEWFDLVFNQRPGLQQHKQQRNKEQERREGTPPQQSSNPACRNVAIEVGPPSMPPVDDGMAPRSPRSLVHELPDDSFFHMFSFHMVAQMSYFLVVVFRLANFEKDDPSCGWDKHWARAELDVPGMVGAIADRFAEVAAYFADHAAVGGFSATAPTMPPPPTGELAFPDFFTRSARAMNMLKATWVAGWAKEDRNNNNNNNNSSSQQQQPGEQPSQQQTPADSVDSDSQDRRKLLQQHQLQQQHQQYQQYQHHEEEMRETQRPDMSFSFSLLNAGPDDALPFESLMGDDLNLDFDGGMGMWLTDMYTSEWGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIU6</accession>
    <name>A0ABR3YIU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamate--tRNA ligase mitochondrial</fullName>
            <ecNumber evidence="10">6.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MSE1</name>
        <name evidence="10" type="ORF">Sste5346_010051</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049940">
        <property type="entry name" value="GluQ/Sye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311:SF2">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="An anticodon-binding domain of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="8">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class I anticodon-binding" evidence="9">
        <location>
            <begin position="215"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="373" mass="41542" checksum="37B298DAABF81E9A" modified="2025-10-08" version="1">MKSDGFPTYHFANVVDDHLMEITHVIRGAEWLISTAKHVSLYDAFGWEPPKFAHVGLLVDSNRQKLSKRNMDIGVDSYKRDGILPAALLNFSALLGWNPTNSSSKGVMSLDDMVKNFGLKFTKGDIIVNAEKLGFFHKKHIQLALSNPSPENNLTLDQYITDSVLQLVRETEAKRQRLLADDLRDNSADENLVSLLGEPILPLFQDDNSTDDTRAYDQIRAAIRISRNEAVTAPSFAEAIRYLVWQPPAAYLEKTSRSLSPPPSRIFIDEVPSSTADVMGYFIDQLEQVDGKGWDVDTIQVSLDETAKRVASCEVEGPPITAGYKFLRWGLLGLNHGPQISHLMDYLGKTETLRRLRLAKTVAESLADSSPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIW9</accession>
    <name>A0ABR3YIW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent protein kinase complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF32">
        <property type="entry name" value="PROTEIN KINASE COMPLEX COMPONENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="43553" checksum="8E4E07D5488A8AFC" modified="2025-10-08" version="1">MSEDDHHSQGSTPDSPPPPPVPADDPSLFSTTSCSDNASDAPSPRLASLTDDIFNVTPLAALQMLGAGIEALVRITGDIPPTPPPLHDERSTPTNMRSMQAEKEVIVRTLSENSLARLREQAEREDRKRKAEEEHSREQREREQKDSTDRSTPPRDENDTTPHTPSTPSRSRLPPTPPPAKPMQMEIDGVHLRTTSPPLNTTDTNTPVSSSGVPILVVPPAEPYIVIGANSQPLNVQHSAITRKFYSKKAPPIGISEYLLRLHRFCPMSTGVYIATSYYIYRLAVSEKAIAVTRRNAHRLLLAGLRVAMKALEDLSYAHTKVARVGGVTEAELARLEINFCFLAGFELSVCAEDMQQHWMLMKSGRAVGSLDQDGTAAVMASMDSLNVTRRPKVEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJL5</accession>
    <name>A0ABR3YJL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000101">
        <property type="protein sequence ID" value="KAL1888072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="213"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="430"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="537" mass="56943" checksum="B1414E8C85559959" modified="2025-10-08" version="1">MADEGRPNQQNPPGREAGIIKSEEEDEDRHRPKPLNLGGDGNSNNNGGSNNGNSDSNRGGGGNIGSGNGNSVTLPSFREAYGTYAQYEPVRPSHHEQSARPPMPGPPRPYGDDPNAHRLPGPPGPPGPHGPPGPPGPPSQRSGPSDPYASRMHPHPEQGYREGYYGPPPYHHYPDQPPPPHGQYWPQQQMPGMPPQYQNGPPETAPRQRTSIACKYCRKRKIRCSGYQNTPDGKCTNCKKTGNDCVFQPVSSTTSTAFVPVSAIQGGVPPGTPLYGAFGQPLGPNGGRGPNGPPGSGPPSSGSMNGPGGHPGYGPTSPGASGYYQQQKHMPPHMDRGAPYGPPHPSSQGPPPPGRQLPLPYPQHQQQQQQHGGYPGDDQRARKRTREEEEAEFPNRLPPPPPYGNYPNSHEMGYYRGPEDARRSPPSMNGSASGPGSAVSPSTSAPRGYGTPAPPVLPPPPMSSVGTDSTSARSSGSVSGTTATPPTEHRGSRSPSGDADEKPKFPPSDYYAFSFQHNKGREPKAGADIDSSMLRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJT0</accession>
    <name>A0ABR3YJT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alginate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045909970" description="Alginate lyase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="47706" checksum="62E3A40BF633A6A2" modified="2025-10-08" version="1">MKLFAILLALSSISCRVLATGGLNGLPVLNGPIPIAPLITGSKTRVGDFVHPGLWHTHDDLERIRDGVLQNKDPWAKVWVNFSSDSYSQASYEMQGPHAVLCRGSCSNYTSFTNDVRAAYQNAIMWYVTKNQSHWDRATTIIDAWGTNLTNIIGTDTSLLVGLEGDMLANAAEIMRWEGGWVEAGAEWYGGSGFSNQLYWLFARQSIIIGQANYGMVSIKALLSFAVYLDDVAMYNYALYAYLNEPCAGLYANIDAKTGQSAETGRDQGHAMGGLGWTAEAARTIQSQGTDVYGEGNNLLLLGAEYTAQYNLGYDVPSFDPTFYRCEAILINGPWAVPSNISRGISETSPQVWDILYYQYVVKRGINSKWLTKAKQAIDSLGGEEHPYGSSPDDHPGWGDLLFSYDSKCTCRNDNSLTIWGGGSIGPNGLGNINAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLW6</accession>
    <name>A0ABR3YLW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flocculation suppression protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SFL1</name>
        <name evidence="7" type="ORF">Sste5346_009046</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000078">
        <property type="protein sequence ID" value="KAL1889188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF396">
        <property type="entry name" value="FLOCCULATION SUPPRESSION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="132"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="592" mass="64189" checksum="ED6E2EBC91336A4F" modified="2025-10-08" version="1">MTAATQSAHIPRMIDGPDEPMASRTIPIMTPTIQMSAPSPGDPMEITTPTNSSPPPPPRSDGKNPDHEANGASGGTSTTAANGSGTGTGTGTGTGTRGSASPPESSEPTPTKPEPNTHLSAPSAAGGNSGSQIPAAAAPAVHQPKIVQTAFIHKLYKQYFKHTNISSFVRQLNMYGFHKVSDVFANGSDSTTLWEFKHGNGNFKRGDLVGLREIKRRASRHSLVHRDYNPQKPPPPSQPGTPAEAIPLPDGSDPRMSGLDHAFFNIETRLQRNEEYVQFMSIKLQTAMDTVGRLLQVNQEMSRVLMNLVPPTDRHLQRDINVLQERQAEMVRNLDDLHDPPFSSSRPYFANVDNAPVSPRQMPQDDPRRSNLSVPQQRPPNFHRPPVPSNLSISTRRPYGSIGGTTQSSPSSVRPQHPPPPPPPSQHPLANVEPSPNMARRHTSADIRAHGWQPTNAHYPPTGGPPLPPTHYPPSPSRAGPPEDQRIRDSFSAYSLQSASQPHSRPETPPPTLPPFANGSNHGNGNGNGPDLGNWSWASANRSNNSLNIKDSSAPPTRRGSMAHILNPTDTAEREDEDGSPREDERKRKRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM11</accession>
    <name>A0ABR3YM11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SMY2</name>
        <name evidence="4" type="ORF">Sste5346_009269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="3">
        <location>
            <begin position="721"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="852"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="951"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1070"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1237"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1454"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1104"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1258"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1457"/>
            <end position="1470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1505" mass="155692" checksum="2C9307ED112239C8" modified="2025-10-08" version="1">MSSNTPASFASAAAGQSRGSRPGEDWSRRDGRSANGTLTFRRPSAAVVNQQSQAAPDASAPVLPSLTESQAARPSLPPYDGTMRYSRGQIVDILKGTQPGTIDVNSLFVEGWNATQANGAARGWGKSLEGTIPQDPTVCWDTSGGVTPMALQEMTEEEKEAFTDVNSTLKPQQPKDSGQIGGGSGNAAGAVNGRKTSISHGTGYSNNNSNNNASNTPSSISSSRPTTRRRETSDTNAFAAGGLTSPLANRTPREESSWFGRKTTDAKDLQQVQHTEEPEGDPGSAATRPTNTATLSRSNTAGSVLGSSSSALWGSSGSAPPPAAGAFGSFALPATTGDKRFGSVRGESRLAHLIPKQDGADTAASGARVASSGTAAGNAAAAPAGAAPAGGAGPKESWRAQPRTDTDPFGDDGHPSSASQNPSSFDTPVKNTRGEFGMSGLNIGSSLDEDPAGSPETNPFRSPPADRSSGGSGGAEGAPTTGPIGGNAGLDHAAVFGSGRGGYPSATFDGSDRSQTSSVGAKGFGSFANIAGWGNPLASSTPDRDRAVFSTAFGNSLFSPGTGELQSPGFGGVVPGGGVFGPSGASGTGSLRTSTSKLGALFPASLQAQMSASQDQEDSGLGDSVPDLRQINPLGAIGREAIGSQVRDSDMGGIRSGRGLFDDPMDPTRVGPAGIFTSEQGSQPNILASASSPLPQHFESGQRPNADTPLNAPRTMVMPDRMRWVYLDPQGLTQGPFTGLEMNDWYKANFFTADLRVRKVEDTEFEPLGQLIRRIGNSREPFLVPQIGVAHGQPSLSGTFAHGDRGTVIPPLVGAFPSYGRTLTAEEQNNLERRKQEEQYVLARQREMLSAHHPPFPAARPGAVGAPGGALHHHSSAHSLQSQPSFGSMTSPLAVAPPPIPGHLGATPGFFDHSGLPATTQPLATASTEFLRDEYNLQDRQMLSNILPPINAAGSFPPQQSSGIAPDHSSLGHLPSVDQLQKDSQGFSERLKEFNQYREQIDAAEAGQFQAEASLTSTSTHGKQQAAAADIVEEVALERRLQGEPGTLVAVGEASDSLASLSLTQQVQKTQAEAAAAKRRGTQSEESAEPPQPDLPLPFPPPANAQSSTPLAAPTAQRTRSTLPDQYATSQSRSETPESGAPSATQQPPLAPWARDPGSESHRGPSLKEIQEAEAKKAAKAEEVAAAARKLAAEQEAALQREREKAVAALAPGLPTSSTWGNGTPVASAAVPASPWAKASGAKPSVASPVTVGAAHSAADRKKTLADIQREEEARKQKTRELSSQSPLAASPFAGKRYADLASRGQPPAVVSPVATSASPVATAAGWATVGAGGKVKTPTAAPAVRSVSAAVTAAKPPVVPATSRSTSRQLSGISGKVEGGVAMDEFNKWLHREVSRGLADDIDVNMFVDTLLQLPLDQSIISEAVYGNSKTMDGRHFAEEFIRRKKLAERGVIEKQASTPASEVKTSGGWSEVAKKGGNAAAAPKEESMPAGFKVVPSRKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM61</accession>
    <name>A0ABR3YM61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000075">
        <property type="protein sequence ID" value="KAL1889381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="36"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="650"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="603"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="724"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="761"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="786"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="807"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="889"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="900" mass="97971" checksum="285C9C756075F323" modified="2025-10-08" version="1">MRTLDESRRRWKETQKDGGDVAALQRAVKFNGPTSPCEAGLRSVCWKAFLLFRDDDSAADRNLVLRETREDYEAMRGTYMRFIKHPERLAEMTDDPLADDPESPWDTFRKDELVRAEILQDVRRLPDDPFYHQEEIQTLILDVLFVYCKEHPDAGGYRQGMHELLAPLVYVLSEDAIESNSLRGVPAPEDADMIEMLDNCFLEHDAYALFVKIMGRARAFYEMSSSSSSANASTATHETGTTSDLFSPLASSSANSAGGVEESAIVELSKEIHEGTLMKVDPELAIHLKNIEILPQIFLIRWIRLLFGREFPFKQLLILWDSIFAYDPKLHLVPLISVAMLLRIRWKLLEADYSVALQSLLKYPAPQPPHGPHTFVDDAIYLRDHLDAAGGSNLILKYTGRAPSRVFSPAGSSPTSTLRPTTPAAAFAAGLGSLRSRTLKVARSPLRVSRHGSNSGSGSGEGLGITGGGDGTSPSPASSRLFQGREGMEALFQGAAKGVLERGEKLGINRAVRDAVGEIKRNMAEARQAAAANRGPGGEGKSVASLFSPTADGKRLSYGQAMRIMTDMERRNQQLARMLDETVTTLKTVARGAPAKAPADTLGEEKSESDKAAAQEEREQQWQEWLEEVELAAAKVQFVKVHLEDSSLTLPVDEPRPASPTEDTTMSVSEKESTPGPSVSSDAKSPADANAAPRTPLLQSEAPDNDFAPVTPLAQTEGSKAEHDDDSMDVDVDNDVLDSPEKAPALPARSPQPQQAEVAPHPQPSQPKQPTPLLVKEEEQRPHTIPTRSTLAQSSFSWMLEPGDTASSLSNNNSGSNNDGARSSSPPKKPPRPTAASRTKHAFLFGEVVNQSPLGGGASDDPLADTQMDGASDGRPRPVTSDEIFGLEPLKRALPKKDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN19</accession>
    <name>A0ABR3YN19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine zipper 2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF10">
        <property type="entry name" value="RICH PROTEIN MS8, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="22430" checksum="0F95B29BEA62B7C1" modified="2025-10-08" version="1">MSAQDYYGSGNQQQQGYSSGQAYGGQQQYGAPPQQQYAQQQYGGQQQYGGPQQPQYGAPPQQQYSNSTSPAPYQQQQYASPPPQDNRGSSPYQAQPQYSAQGPIPATGPGGAAVGPNGETDERGLGATLVGGAGAGWAAHHAGGGALGTIAGAVAGAIGANVIEHFVEKKKDEKHNQQQQHQGGYQQGGYYGGPPPPHHGGHGGHGGHGGHGGHHGGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ03</accession>
    <name>A0ABR3YQ03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="150" mass="15243" checksum="B0B7E7A7E80FD2B0" modified="2025-10-08" version="1">MPAPVAVYTNMPRAGEGLTQELQPEYEGTSPPPTPPVSKINTANVIVVKVALSKDEALADLPALFGSGGAKALVIAGFVSDEDADAVTAAVTAAQAGVRIARLSRADLEGAGVKLPPPGTPMPTGPPPPGTPRPDPAVFTRLFKEKLAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ83</accession>
    <name>A0ABR3YQ83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="594" mass="62029" checksum="7F730A7C3556A346" modified="2025-10-08" version="1" fragment="single">MNSGGSGRHRQHQQHQHHHHQQHPSHGSTGSIGGTGVPLPPPFGSATSTSTTVSTPTPTPTPTHADFGTPLSTSATPAGSLGSLGSTAGSVTGSASASANASASASAGLRKERGAIAAQACDTCRSRKQKCDEQRPKCGTCQKFKLACHYREPQPTKKDKTLGEILDRLKSLEGKIDGLGADASARPPTAGVYGGSSVDSAMLVPPPTATAAANAVSVGAGYRYSPAVYQMLGWPVIQQMLAPLAPRLAVHQVHVPSLATEHDALSVILGLHHPQNRLPSDESTGVNLGMPAVPGMGVGVDVGGMGAPTAGFYPATRVSLTSSMTLPLGASLGSTLGTSLGGPPLLSWDTLYRLSTAYFDSFNYIAPIVDRQSFLGVTLPAALEVGADTTNPTDKSSAGNDTNPNTTLVLLVAALGDVAIAGVQGAPVLGATGGVKGGTVRHPPGLALFNEARRRMGFVLGDCSLESMQIHALAGIYSSTCLRHMDYWRYTTAASLSCQALITSKPSELSSPHADLIRQIFWYCLIIETHFNIELGLPLTGLDRYEDLVGLPSFSGPYSQDDYLANQASHFQEHFASQIVLRRLCVAFHNTLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK9</accession>
    <name>A0ABR3YQK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000071">
        <property type="protein sequence ID" value="KAL1889669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="51861" checksum="829FFC15AA15D780" modified="2025-10-08" version="1">MSNGTGHDEPVEERELPPGFSWGVATAAYQIEGAVAQDGKGKSIWDTFTHLEPSRTNGENADTACDHYNRMPEDVALMASLGVEVYRFSISWPRIIPLGGRNDPVNEKGIAFYSSLIDHLLACNITPVVTLYHWDAPQAIYDRYKAFLNTAEYRADFLRYARVCFTHFGDRVKTWITYNEPYIISIFAHLNGTLAPGHCRATNHATGTEPWRVGHTIILSHADVASLYAAEFHPAQQGSVSVVLNGHFYEPFDAACAADRTAAENRMLFYIGWFGDPLFLGEDYPAQMRAYLKDRLPVFTEEDRDLLRRTAPLNKFYGMNHYSTKYARALPTPPEDDDWTGNVEETSVNSEGQEIGPRSGLTWLRVAPQGFRKLLGWVWKRYRRPIIVTENGCPCPGEGDVGVAVDDRFRQKYFGLYLDAISRAIYEDGVRVDGYYAWSFMDNFGLFSPKPPVSRLSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRA5</accession>
    <name>A0ABR3YRA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carbohydrate esterase family 5 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008027</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439132" description="Carbohydrate esterase family 5 protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="18679" checksum="81C01F3C1E97BE72" modified="2025-10-08" version="1">MQFLLFILTFAAAAAAVPVYLAIRTTCYSGVYVIGARGSEEAAGYGSVASVVSGVLAAIPNSRGIALDYPASVLDPLYDDFVTGGINTLISLVESYASSCSGNIVLVSFSQGANVITDALAGGVLKPTPLSASYASHISAITVYGDLTFTHGQSFDAGTDTGTDGEVPTWGTDAVDFIISKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRW2</accession>
    <name>A0ABR3YRW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="354" mass="37186" checksum="88DBA79FF0FC3F9A" modified="2025-10-08" version="1">MAGHDRDHDHNNDYDVDELDSAAVAAAMGFSSFGAQAPLNKKRRFNPQADAVIGTPRDGRPPARTQVYPAGTGANATKLPPRPVKTMAPATAPATTSLSDLPLHPPQPQNSAKMAMKLPPPTKTNTDEIDLDDDDDNNGEDDKEAGGANLETGGDADANDEPGPQYLDTSRPVGEIRDHLGNSVPENVEEDPVALQARIDAVVAAGNAAYGISPAAAAAAAQQLDGAVHSTSRHHGGIRPVDRHGFNPDLMPSAGPQFGAGDAAGSEAADSEMGDESSLVGSTDGRGQWQGRGGRGGRGGHGSHAHGGHQRDWWTGYYDPTSNENPWARIEQKLGLPTRGSNWLERDHGRVQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS06</accession>
    <name>A0ABR3YS06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123:SF3">
        <property type="entry name" value="NODB HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="76"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="331" mass="38325" checksum="5F07E2402BB47508" modified="2025-10-08" version="1">MVHVEESLQLPRDFEGDFDPQWPNGARIAVSFILNYEEGGERNVLDGDPISEPYLWEKGASGGGREGRHVNGEQDFEYGSRAASWRLMRLFKHFGWQFTTYAVGVALQRNPTFARALVRDGHEIACHGVRWLDIWEYGLEEDKAYIAENIRMLHEVTGEMPVGAYFGRGTPNTRSLFPEVWKKMGGEFLWSSECYNDDVPYWIDLPWEKTLPESEREGMLMIPYNYDCNDGKFHMSPGFGSSVAETYEQYLKNTFDCLYREGGKMMNIPLHTRITGKPGRSEALRKFMQYISEKPGVWVTTRRDIAKHMRAKFPYKPEGKWMTPEVETKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTK8</accession>
    <name>A0ABR3YTK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 74</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS74</name>
        <name evidence="7" type="ORF">Sste5346_007813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="351" mass="38821" checksum="9BE41A2E9919210C" modified="2025-10-08" version="1">MSATTTTSGLTRRRGGGGGGASAAGANSNGADTSDPSKDSAPETSYEQGDNGHKIAFDPRDLSESAERSKQPKLTLMEEVLLLGLKDKQGYLSFWNDNISYALRGCIVLELAFRGRISMQKDPARRRFPLSDRVIEVIDDTLTGEVLLDEALKMMKASEKMSVSAWIDLMSGETWNLMKIGYQLKQVRERLAKGLVDKGILRTEKRNFLLFDMATHPVADGGAKEEIRRRVRNVLTQRTIVLPASQFLPEDLEFRNLRTIAMVCAAYAANVLENALSTLGHEARERAFAQTDELLNEYSVWPFTRKATSHGIGANLPQVIAEEIAKAKDKELQLEVVAACLNVFTRLDSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR9</accession>
    <name>A0ABR3YTR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GIN4</name>
        <name evidence="14" type="ORF">Sste5346_007509</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.220">
        <property type="entry name" value="Fungal kinase associated-1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031850">
        <property type="entry name" value="Fungal_KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043024">
        <property type="entry name" value="KA1_sf_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16797">
        <property type="entry name" value="Fungal_KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="172"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="132"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="663"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="781"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="898"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1129"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="666"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="816"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="984"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1003"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1016"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1030"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1041"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1072"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1141"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1177"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1891759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1326" mass="148345" checksum="62FA1F37018274E1" modified="2025-10-08" version="1">MASRASPSRTGNRVPFGDATSRANTPNAPQVPAQSNKHATGAYIENSDSTANTKLSASLSAVAPGPASVDQQQRHYDQYYQEYQQAYQQQQAAQQHAQQQHANQNQHQQRQHHQQQYADHDMTDAPLMDHAEASKRNSAASRDSQHTVDSKRASQYSSCDGFPNKKSHIGPWQLGKTLGKGSSARVRAARHCTTHQPVAVKIIAKKTARMTQSGSIAQLDQFDSNLPENVNGVRRMPLAIEREVAILKLIEHPNIVKLYDIWENRNEIYLILEYVENGDLFTYVSQNGALTEEASIFVFRQMMSAVQYCHAYNICHRDLKPENILLKADGQIKIADFGMAALHQGPRYHLQTSCGSPHYAAPELLKARPYRGDKADIWSMGVILFVMLAGRLPFDEDDMGLMLAKAKKGIYTMPSSFSPDAKNLVHRILQIEPEVRISMNKMWQHPLVWKYGYLDDLGSNGTDGQGQGGRGTQVTPLDLANIDTQIFRQLRSMWHTLREDDLAAKLVSNEPNDQKLFYWLLHGYRERQQEDYNPTLTHSVSDYHHVNQVYSKKVSTRKFSNSNAAGHKRSVSRFTVISNVAETEAGTEAGTVKSYDPYKSSIIMEPSDTRASHAKIVVHRNNPNVEAEVRSMVQAEAMKAKASSAATKKKVYVQQRRGSAAYLKASRGSMSSIRSTRSMRSMSGKQGVRPSSRHKRGVDFSKARKPSAYEVEADTEPLMSGANGVPQSRDTTPVWNEDLTDFSCKIAKDLDDAFMSSLLAVDSSEHDEGRDSPYSIRISSQELAEAPAPPTQSSQSKKYKPWHSRPLPPSPPRSESVQREIAKAKDKEQKRPKTSAGAKGTRHESAAIGVATSSNTKLQARIVDVQPFSNGSDDRRIVSAPVYSQSGKPGVMQLPSIYETGQENWPLADKDKPRASSAPSKKNAPHKAQDIEELAHMAQAENTIRLVVSPTNTRPKGPISTPRPISLPKKVSRAEPTKARPVSDPQQNTRQRSLENLKQAHTSDQQSLRQQQRPSSRRDEKAAKYRPELITETIVEETTVSNHGSMSGGSDRSSVLPARRSWFKRQSKTDIRNSAVQVSERPVSQISRHTEASVAAPPQALSRKKSFIFPFWKTKSDAKLTAADEDSQFEAEGVLERPRNSRMNSANSRSSRNSKNSGNGSQRSKNSNKGRSAHAGWNDHDDEPARKIDPQQNWLSRLFRVKPATRHLCLGMSQRRARQEVVMLLRDWRRYGIRDIEVDKERNIVFAKVGSDNYLGIREVSFACEIITVIEHGKRNHLCILRLTQEKGSANSFHKVADTIKGVMRERHLLVPDKRKAKMMVKTLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUJ0</accession>
    <name>A0ABR3YUJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione S-transferase UstS-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="1">
        <location>
            <begin position="119"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="253" mass="28110" checksum="EA2136A37DE6EE6D" modified="2025-10-08" version="1">MASLPDIVVYDTPGRDIPLWSHHTLRALYALHRKGLPYTVMSVDYPDIESTFEPTSLPPKDDPVERYEIPVVLFRLKDIENNSTDEYLMEPSRIIAKLDELVPDPPLPFASEHATEARALFSPALAPILQIGVGHIPSVLSDRSREGFLAKRHARWGKPLEEWVAERPKDMLLATAEPRLKVFADWLEGSGREGPFIEGAESGYADMTIVSILEYARLVGATDAFNAAMAHPAIARLYNALPERDGVRSGIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV13</accession>
    <name>A0ABR3YV13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141:SF1">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1025"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1065"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="483"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="831"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="913"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1154"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1296"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="508"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="834"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="919"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1165"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1222"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1300"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1348"/>
            <end position="1360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1360" mass="148394" checksum="D11FF6A9BEE1A5EA" modified="2025-10-08" version="1">MASIASSAPDPRHLQLIAASAQANESRVREILAEESVWSTRHDHDALRQSLQKVAARGNLAVTRLLLEKGADVEPRRESEMPALFKAAEAGHFAVVQELLQHNANPNFVVRSRLGQTALFPACFRGHNKVVGLLLDHGADVRIRDKEGRTPLLYLASEKEKVKWTMDTLKLLIDRGGANIEVRDNIGRTPLLWAATNGNLQLVEALLNGSLGGAQAAEVSAANNRGRSALHLAAEANHEAMVRLLLQHKADPNAVSDGGWTPLHNAVQNGHAGVVALLLAEDANVNAELSNGMTPLHWAAFNGFETVVKLLLARDETKLDVKDSFDRTPMLCAAERFHRDIVQLLSPVHAARRLSPAARAACQEFKATVVDFGNFRDGKQHQVFKRSVFDVLYGWDEENGKPKIDTQIKNIKYQPDFRWIHLPANNIAWVETLLSKWFIEGGSRDIEHFKALEKCFDQEHRGPLAHAHFMRTYCHRIASLHGHGQNSVNDKDSKQPFPPLSEEPTDASVASTNMTASTNLSKVSTAVSADGTTTPTPRKASAADIGEGSSGTPRSDKKKGKGEIIAERHPRRAKRASGPPGNPPGTKAMKAAAAARSAGTQPLVWDASKLPSLNGKLVLFMPFLHYETDERRQRMTHAINLVRDGWDPPEGSPRDIMLTKGYICNTPPLHPRRTLDQFFYHGIDTSIRDTDQVVYRYCKRHDIEKKVFMVDQLWLWVLGKDLVVTCFPQRWDQPARDPLNVVDGIIEETNAKTRPPIQSVYDLAMLITNRCSGMFDRYRLADQDYQFLDMFESSIGLVTNTESELFSRFNKASELSAEWLELHRRPSRRHVGGLASSLSSPSQPSLVPTDASGDGRLHATVPVFPDALLDIGTETSLLAEIKDIRDELNILAVVLASQKATLDEFESHLTEELKPDGINTSSRRANNNSNNYMPGTGPGGMPSAGIFGTPITVDSVVNEIRKRSRDQRRLLEIHQKDIDRMDRQAESIYMSLTNLLDLKQKHSNALEARFARDHAMIAARQGQTIMAFTIVTIIFLPMSFISSFFSMQITDWATDLSLGYVSKYLFGIGLGISIPLVIMAFTVSDIYDAVHNIMAAFHLQRAHWHQRLHKRSGGVGADGNPRADLLSLPGGGKGKADSDMDSLATIEKVKRNLLMGSRGGNHSRNGGGGSGSGGGIFGGGGGGGASGTGGGGRKSRSWSIGGGASGGRPAFRYSNGGPAGDGGDRSNFDRDRSRDGMSGTHSHNPSHGRYESTDDGHQQLHDLRRLSSHQRQINALHPSLNPHPHQHQLLHPPAWAVAAGTGGSGGGMVPRGGGPGSAAAMSGGSGGDIAHERKYSAGSSAGRGWRASFEKTRDLEKGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVP9</accession>
    <name>A0ABR3YVP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="592" mass="66955" checksum="33E18CACD0E64590" modified="2025-10-08" version="1">MKLLDCLTKQIVEFVQDVPKYAILSHTWEDGELTFALITQAKDALRKGKSCDVTKRQGWPKIHWACEQALKDNIYYLWVDTVCIDKTSSAELSEAINSMYAYYRKAAVCYVYMYDVCNGTSLLSTPGHGACSTNRVVPFEKSRWFLRGWTLQELIAPQNMSFFDHHWNEITTKKKSLPLLAKITGIDELILDGGNLRLVSIARIMSWAARRTTTREEDMAYSLLGLFGISMPMLYGEGSEAFLRLQKVLIETYNDQTIFAWEFPPANTLEWDGVLAPSPRVFLNSANMSPHQYSYVSPKMSWKVKPTTITSRGVFFNSCVFATRTILELPSLQGIIMLGCVDMAQRSSMQPSSLITIDVEFTDNTRQSCIRRRNTPLRMRSGRSLDEVHDVYTKASGSYAVWDLSTDKHCIVQICTLPKWPPKHSYTRIFPTAAAHDQPPGLQVVVPDCAFIVYRQNSNSARRVPTDDEIQHKISHLVIYLVHKAHLGLASDYDLELASSGTTPTGLAVAVRSYEGYAAVLNSINELGSDLTYRELSSRAVEHQRPGLRLNANLDVSDLDGSYCLDLFAHPCDESAEVKYSRREEWRTEPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWM7</accession>
    <name>A0ABR3YWM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007474</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DIF1/spd1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000050">
        <property type="protein sequence ID" value="KAL1891724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013900">
        <property type="entry name" value="RNR_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081:SF1">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08591">
        <property type="entry name" value="RNR_inhib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="345" mass="37001" checksum="1ACE44A3532741F2" modified="2025-10-08" version="1">MATPRVKRPFAGSSSDPSQRQITSFFDRSNDVDSPSDSRPSIERRSSTPLLPPGVQANLLAVGMRVRKSVPEGYKTGKEELMESSPVVGPRRAAQTTYTAPVAAPPAPSYNNTFTARQVPVQRELTPFCGLHKIGGLGVQSFGDDDGRPMFAASLFDGSADLDGGNDDSEPPSLTSSQETVSSMTSYYSPPSSQSRFSSASSRFNNSFNAASASTRKRFFGQEEDAQTDASNSNSLFQVHEDARLPASASSSSSINRWLTDGNVGVGKSSMAPPQGRRVLAIPRRRGKSGEQLPPLKQQGDGQQSVRFLDQENVEIAGDFDEADFLDASMLAEGNGEHDMEMGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWR2</accession>
    <name>A0ABR3YWR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GRX3</name>
        <name evidence="5" type="ORF">Sste5346_007016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="257" mass="27739" checksum="ACF1B2E333C0CBC3" modified="2025-10-08" version="1">MSTIQEIKSVDEWDAHLRALDPSTLLVASFHAPWAAPCAQMATVLQALADEYPSTPKPPTTSWVSLNAEDLSDVSEQYDVTAVPFLVLLRNGQVLETVSGSSALKVRAAIEQHAKAGAAAAATGGQEQSSAEPIAPIAAAAPDPAQQKEELFKRLGDLVKAAPVMLFMKGTPGEPQCGFSRQLVAILREHGVKYGFFNILADDEVRQGLKEFADWPTYPQLWMRGELVGGLDIIKEELESDKDFFTEFSVKPSATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX00</accession>
    <name>A0ABR3YX00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="46201" checksum="C662F67AF197FADC" modified="2025-10-08" version="1">MLLSESLGGSRGPEPAFVESGALQTPTTTPDGHSGDQDGDREEDPKEHSTNPNSLSAPFSLSFQPKSILEPADHLAQLIAKSLAATAAAVSAPSNHGHHRKWPRLYHGMFSLGEVARLVGEYPMRMLHPTFCSPFIHPTLCRQRPDGKGGKGPPAPLAVAFACVSMKMHMEGEGKEFVCETMSQERDKLIKQLPSILDNYEDTCVILQALCIYGIEALIAANRFPSRLNLAVLHHEYLVRATRRLLQQIANTSLEGCFSNSFLGSPYVVTVDWKTWVVHESLRRTLFLVYIIHELLHGAETLDHAYFEPLFTKEEGGIHEHIVLPSSDALWEAQNEDDWRRAVESEAQQFQKDTALKLGDAERRVAGEDEPWMLTEFPQLPELTRLILSVSPLYGAAQRCTFSQQMLGDPTRSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX07</accession>
    <name>A0ABR3YX07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbonic anhydrase</fullName>
            <ecNumber evidence="5">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006806</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03379">
        <property type="entry name" value="beta_CA_cladeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175:SF3">
        <property type="entry name" value="CARBON DISULFIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="18206" checksum="EB59AED16BF22C50" modified="2025-10-08" version="1">MTTDIQSNLEAKNGAYAAEFTKGHLPLPPGKEYLVVTCMDARIDTAAAFGIDLGDAHVIRNAGGSSRDALRSILISEQLLGTQEIVLIKHTGCGMLTFTNEDAHALVQKNLGPAAAAEIATLDFLPFPELDQAVRDDVLFLQKQNTIPESIAVSGWVYSVETGRVRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY42</accession>
    <name>A0ABR3YY42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription initiation at TATA-containing promoter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BDF1</name>
        <name evidence="6" type="ORF">Sste5346_006478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="417"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="651"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="5">
        <location>
            <begin position="881"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="507"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="593"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="747"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="838"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="959"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="843"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="858"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="987"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1025"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1042" mass="110526" checksum="0B67FBFD6C813A7F" modified="2025-10-08" version="1">MAVMTSPHPTDIASLDQKQPSKMASLTEDLPTSNGVNGHTDASSTSPKPESAPLAKTDSADVAENISKNAEAFGADSTTSALEKTPTPDAPESDKPADDDTKPEPAAAAADEPASDAEKKDDEPAEAPAARVEEPAAEAAPKEANPEAAAPAPAEAPASATPPVGDAAKEASAEAEKPAAESVPDSAPEATPAAEPASAVEDAPESDSAAKPAEEESAAAAKPASPSAAAEAKDSDADVDMIDVTPAPSENATAAAAPAAAPTPSPAPVSKAPSPEKAKSPPVHAPLTHSLSSSLLPSLRDDRSRENSTNAAAAHDTIMADASGGKVSREREDDEDVAPSAKRAKTEDAEAPAAQTISQSEAPAAGTEMQIDVAPVTMPARVRAVAKEGSLADPKLDDTPISVYASKEIRRVLASVKKTKAGNNFKDPVHKKWPMLWDSYTARVAKPMDIGQLERNLRENVYNTHGEFTSDLFLIFENSVSFNGLGNAVTDEAKSLVDNYFTRLSEISAQEPQKPEKKEPKQLPTRQTEPRAATNRRESRGAASSPIEDSVINVSAAPPTLSTSFGAGAKASSPGAGGASAVEASTPVFAVPSSGVPIIRRDSAKNDGDRPKRPIHPPKNRDLGYEPKNPKKKSPEFRFCEEVLKELVKAKHYEINHWFLKPVDAVALQIPTYHKVIKKPMDLGTMQTKLNLGEYVSAKDFENDFGLIVKNCRKFNVVGEVVDSANRLEDLFKQKWAEKDSWIAAHTTQTAAHSPSVKDEDSDEDAEDSDDEGGEIVAAPLSSDTVNALVKRLDEENARLNKLLEAAAPDMTMITTQQVVTNMIQKQIVEEKIKLAAAEADRRSKKPAKARPAKGKKVSGSSGAAAKKAGSGAAKKASGAAVKKAPKPRHFGQAEKNVVTEGINNLDGNQLEKAIDIIKKDTSQEESETGELELDIDQLSQDALGKLYELIVKAFPHMRVKSDKVRSTGDGSGSKQSSKPKKHKPMGKLEQERNIEKLREIKAQFQRPGSGSQEPLPSVEVNQNVEEEESEEEESEVDSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYD5</accession>
    <name>A0ABR3YYD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Choline kinase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007521">
        <property type="entry name" value="Choline_kin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04428">
        <property type="entry name" value="Choline_kin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Choline kinase N-terminal" evidence="3">
        <location>
            <begin position="317"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="765"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="888"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="803"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="973" mass="106416" checksum="0BB47544DC29D493" modified="2025-10-08" version="1">MSNPPAPTSSPRSVPLRSALRDDSERTPPLSGLTKAVQIAEPDVTDVLEPPPVEELPPRKQFTATVAKRLSGRAAVLPVPASARNSISSQASLDGSLATYMTSPAQLAVDDVANTARPGASPLMRPHINPLQQHHHQQRHRTVDHISGRLLAQISEWIQHERIKKAARKSRKVRAHGSRKNRSPPAAEDVGSGSSSKHRSSKTTRRERMGGDGTVAPEDTTVAPTAAADDDDDDVTPMGQSTVARHHRAPSTGSASSEVSLDRLQRIIDDNVSALGIDLANLRFGGSGGGGSGLNNSGRRHSRTLRYHPSRTASSDTEYMDGDVLVPGCDAILDNSKTLKYSMSTTSIPQLNRAASDAGSISSRREDKERQAWYKFKNEIIRLAHTLRLKGWRKVPLDAGETITVERLSGALTNAVYVVSPPADLGGGNHDNNGQGHSGGSGAGMSPLVTPMGITPSSSTLSLSGAAGTSGGGKNVLPNKLLLRIYGPQVEHLIDREKELGVLRRLARKKIGPRLLGTFGNGRFEQFFTATTLTAANLREPETSKQIAKRMRELHDGIELLEEELDAGPTVWQNWDKWLDAVEATVTFLDREVSLGAERDRLQQQAAKDGVVLDGDVVPQQTGSFIDTWKSKGYVCGVEWPRFKALLEKHREMVKKYYGGSHRIRERLIFAHNDTQYGNILRIRPDERSPLLQPENEHKQLIVIDFEYASGNLPGNEFANHFTEWTYNYHDATASHNCFPKRYPTPEQQRRFIRAYVDHRPEFPHQCASSTPRFGPMSLPPLPPLMEQPLSEPTAQSSGTASAPPTLQAAHAPPQPPASSASSIVDFMLDARAPPGGWIEEERRRDELLERQVDELMEETRLWRAANSAMWVAWGIVQAKVPGFSLPPKEGSSTASLLGADDDVTIDGEVNTEGGADADDDDDHAAEPEEEFDYLGYAQERAFFVLGDCVKAGLLQLDELPADVQAKVKMIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZI6</accession>
    <name>A0ABR3YZI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="147" mass="16051" checksum="0FF71BEDF7F2D9F3" modified="2025-10-08" version="1">MTSNEPADEAKHGDALNHIEAIQNNDRRITGDENDTSLDDSKGSEQEESDTPIDTSHTRTRRLRANDALPNKQPPLTSLTPTKTRPNQAPLLDLQPLPSIAPMINPLPLPPGTAPPRAKLAVQLKMNLEIEVMLKARVCGDVVLTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY7</accession>
    <name>A0ABR3YZY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006469</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="30"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="529"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="547"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="597" mass="63924" checksum="4F3B4BDB9E28B0BE" modified="2025-10-08" version="1">MAKMTRQQSAVEKALYDQTDLLPKKKLVVVFGTLSLTLLITFIDQNGISVTLPTIARDLDAQNTISWAGTSSLIANTTFQMLYGRLSDIFGRKRVYLGAVGCLALADLLCGLSRNGPMFYVFRGVAGIGGGGVTNLSMIIVSDVVSLEQRGFYQGIIGACVGLGNLAGPFLAAGLTARTTWRAFFYLLAPLGVVVGCVAAYMLPSNPPKGGLRENARKIDYWGLLSASAAVILVLIPISGGGSYFRWDSPMVISMLVIGSLLFVFFIVVELRIAQLPMMPMQIFKSHVITVLMIQSFLLGAVYQISLYYLPLFLQNARGYTIIESAAFVAAMVLVQSSCSILSGQYLSRMKRYGEVIWCGFACWTLGAGLMLLNKRTTSVAAIIVPLMLVGAGLGMTLQPTLVALQAHTTKARRAVIISVRNFFRATGGACGLAVAAAVLQAALRSNLPTEYAYLANNAFYLPSSFSSAAEKEAVLDAYMAASHAVFILQVPLVSICFLTCIFVKDEGLEPTDVREAKKKAALEGKTEGEVNGGVVEAPVEAREADADLEANEVDSEDAPQSGEDSDQTAGHEGAADGRKSLHEVPVRHPVSFSEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z127</accession>
    <name>A0ABR3Z127_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ARP2</name>
        <name evidence="2" type="ORF">Sste5346_006147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="390" mass="44085" checksum="82578B003B4065EF" modified="2025-10-08" version="1">MANPPPIVLDGGTGFLKVGYAAQNFPEFQYPSIVGRPILRTEEKGDNDLVIKDIMCGDEAAAARTMLQISYPMENGIVKKWDDMQHLWDYTFYEKMQIDTTGRKILLTEPPMNPLKNREQMCEVMFDRYNFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLNHLTRRLDVAGRDVTQNLIALLLRRGYALNRTADFETVRQIKEKLCYVSYDLELDKRLSEETTVLVESYTLPDGRVIRVGSERFEAPECLFQPHLVDCEQPGMAEFLFNTIQQADVDVRSSLFKAIVLSGGSSMYPGLPSRLEKELKQLWLTRVLGGNPERLSKFKVRIEDPPRRRHMVFLGGAVLANIMADKESMWVTKAEWEEQGARVLEKLGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1E8</accession>
    <name>A0ABR3Z1E8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome regulatory subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPT1</name>
        <name evidence="9" type="ORF">Sste5346_005923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="214"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="439" mass="48949" checksum="662C63C9AA3AF8CA" modified="2025-10-08" version="1">MPSATGKDWEKYQKKFADDEIEEKKIAPLTDEDIQVLKTYGAAPYGAALKKLEQQIKEKQQSVDEKIGVKESDTGLAPPHLWDVAADRQRMSEEQPLQVARCTKIIADDQDDSKSKYVINVKQIAKFVVQLGERVAPTDIEEGMRVGVDRNKYQILLPLPPKIDASVTMMTVEEKPDVTYGDVGGCKEQVEKLREVVEMPLLSPERFVDLGIDPPKGALLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELITQLDGFDARGNIKVMFATNRPSTLDPALMRPGRIDRKIEFSLPDLEGRANILRIHAKSMSVERDIRWELISRLCPNATGAELRSVCTEAGMFAIRARRKVASEKDFLSAVDKVIKANLKFNSTASYMQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1U0</accession>
    <name>A0ABR3Z1U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein S-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_006047</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="596" mass="64380" checksum="EA97E768E30832C0" modified="2025-10-08" version="1">MWLWDNRSKTQLDLPGEFAVLSDGYEGIWITDAIDFAITGGDLPAVHELIRLLGPDVLYLCDMGETSENLTPTALHLAAESGRVDILTVLLDYRDSLPPDERDQREAAYEQDELARDDPFQRPWGTPLTTACMAGHADAVQLLLARMPEVDINASDKFGYTPLQSVARYALSVGPDRPYMDPDEPARRMAIVKMLLAKGAVPRATDGRTEHYFRYTGRTARPNPLILTLMADRGQGDAALTRFFINKVGIDVHAGFSWCTARMDGRGVNGVADEDVNGYDITATNDINVYLTPLATGALFGNVAGVETLLRTPNTNFAADLVPATGLPPLHAAMVGVPTLKAAIREPGGPEPSYQRPILFVHDNKLLLGGNGQMDDSLSDEEREAYWAANKAASVTDRAAYIDARVATVQLLVAEAASVCKSFNINATHAGYTPLHLGARFDRLPLLRVLLDRGADPRIPIPGPGGRSVFAAVVASIHRLCVAQWSRVADDQPWYSAGGTRCTDYNAVVQSIGARVGEGMTALLRELMGDSSVNEADADGNTALHWTMGYSLPSATKALLALGARADGQNHAGEVPTDGTVPTTTRRIPAAFREYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z292</accession>
    <name>A0ABR3Z292_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005696</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14559" checksum="4B229B5089B06C25" modified="2025-10-08" version="1">MFAARPTFCVAAAARAIVLAKPQTRSFSNLPRLRPTSATTTSIFRSPIQIAPSAAPSLEVSAAADLIAPSSISRHPALAGAFASQIRCGPRATMAFATRLIQKRRHGFLSRIRTKNGRKTLMRRKAKGRKRLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F2</accession>
    <name>A0ABR3Z2F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006026</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="59"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="60141" checksum="8278E81C3D618739" modified="2025-10-08" version="1">MDTEKGDISGNTVPDNASGVKVGEVVRTDAALNEAADIYGDLETAEELRYVHRGLKARHLQFIALGGSIGTGLFLGIGGAFIKAGPLSVLLGFSFTGVAVLAMMNCLGEMATWLPLPGAIPQYCARYVDPAMGFAVGWNMWYLSAIAICAEISAASILVGFWNETITPAAWISIIIPIVILLNIFAVSVYGEAEFVFAAVKVIAILGLLIMSVVIDLGGSPTHDRLGFRYWYNPGPPMKELVAKGNTGRFLGLFSTLLYASFSFGGIEMVAVAAGEAENPRRNIPRAVKRLFWRIVSFYVLGSLAIGVLVPSDSPELGITSPWVIAANHAHIKVLPSIINAVIVTSAASSANAFLFVGSRYLFALAQNKQAPRVFLKCTKRGIPIYGVGFTAIWTGLTYMTVAASASTVFFWFVNLGTIAALMTWVSILVAYLRFRTALIAQNVDRNTLHFKSAFQPFTAWFALCYFVMIVFFNGWETFTTGNWSTSNFITAYIGLPIYFGLYAFWKIFKKTKAVEPANADLWTGKAALDAEEWPEVPPRNWVERVWGWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Q1</accession>
    <name>A0ABR3Z3Q1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transmembrane osmosensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SHO1</name>
        <name evidence="14" type="ORF">Sste5346_005553</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Forms homooligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="239"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="205"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="298" mass="31786" checksum="F5B916CB2B55FF7E" modified="2025-10-08" version="1">MEHSRAQYGRRNGISLGNIIGDPFALATISISALAWIISFISSIVAQIQTKSNFPTYTWWTIVYYFFVIAGVFVVVASDTSQTYHVAVVGYLACGLVLTTSSVNGLVYSSNGAKEAAAAGFILLSMVTIVWMFYFGSAPSAVPRAYLDSFALTKESNTNRQTMVGAYGVGRPETSTSAAPPQMYTSAQLNGFENSSPVTGIPTGQRNSALNGGGFGAQTNKGGAGAPGGTEGEIVPPTEYPYRAKAIYSYEANPDDANEISFSKHEILEVSDVSGRWWQARKESGETGIAPSNYLILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Q6</accession>
    <name>A0ABR3Z3Q6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="674" mass="73412" checksum="862580C6C317933C" modified="2025-10-08" version="1">MTPLPSSDFDLQHWSLVPQCGICGTRVVKDDQFVALSGTLDGSAFASCTEPMSFIAPSTVKAYKNSYLCRWAGCKTCVVAPDVVTLHADCLEVYEQAATKDNETAEKARQRLWIAASWRTPWKKAPFLSLFQNDNAQLSMSITLYKHLGISGMARMPPELASNIRELSKDSPLWRLNAAAYLALSLAEREKHEIAEPSKDDAAAHPTSIPLSKVEAWERGGQLVRREEKETTTATTDDSFIRLTVDTHGLLRIERLPERPAYDGTTSAGELAYALCEAKILDGADGAEGAKVHFQLGLGRLELPSGLVGLQIWDTPVPPPIKDVAYMRKHPKRVGPSSYLHVVDLDPEGNTVTGLTLLSNGGSLLGVHAHTAAKPSAAATAARLTVSTEDPLWQYMPLAPGDRIEAIGVRKDAYTPYLSSDAQGAMSLMFRKTLTGDTLLGYSLYDAPCETIMTAPLEKPRALVYSAVNSANGVVTDVGVYNVAASSHAAPAVRNGTRRHRFNHSAYPGDQLTEDAFQSNVPLAGVTHAQVFTYVSEDKDNDGLLRGIVLTYENGGQRALGMCCVAVEDNTKSIDEYARPVRLCFKSNVETGVTRLRVITEADLGTPAADGHGDDCEGGDNGVDEGYAVLRACCLMTGRLEFDVDRDRLVLEHFDNEEKPDNEYDEENEDDDVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P7</accession>
    <name>A0ABR3Z4P7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lpxtg-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949442" description="Lpxtg-domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="63167" checksum="D3F5AA29BADE63E5" modified="2025-10-08" version="1">MWPSLALVTAVALVGPATGLLVAPNSPCEQYCGNVLSTTTGADMTCDDSLYSSSAAGIVFESCIGCELKSAYSTGNVSDLAYLLYNLRFTISYCLFGLENNTNVAGSPCITNPACGLLEDSFNYDNLTVDVGPYDYCQGWVETVVPKCQACLGSGGTNSFMENYVTILDAACRQMPDTGVTLSVTGTPFSTVPMNVTTPSVVPLYTYTPKYEAISLGGKVGIAIGGLVLLLSTAGFLIVCLGRRKRRTYLKSVEARYRNGGNGGGVLGGNGSDVWPSPNIGHGNKAHEKYSTPTSSQPLRGWDDTPVSASTMTEKNGGFFPRYFSPYNSQYNSPVSAEDGPPYTTWPTMASMTDTLAAGSSSSAMGGAGGRSYAIGLRSVSPVDDAHDGSPGSSTGGHDRKQWQHKYTQEEIERMAHEYELAQIGVALGGTDPSLRSKNSNVSLEGSSNKSAVGADDFPTPPQQHAPVQAAFQQASVHGESSSSSLSSMSVTAGALWDQPSSSSAKRKKRSKKSRQSSEPSDNESIILSTMRRPSGNELELVPEPQPAPAPTLQPPRAIPYYPPPPSPQMESPYGESPYGESPYGGLTAEDARHGHAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Q8</accession>
    <name>A0ABR3Z4Q8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="51513" checksum="5874D767FF9D06EE" modified="2025-10-08" version="1">MATPNAGAATGGGASLVVNSMPPPMGTAIGAASSPPNFMGGPCSSMSMGIGGPSSVSSVAATSPGSVTSTTSPASVSSVLDTPTATSSSAQNNTNNPNAQPDQNPATTPGGSSTLSAKEVELQRKRARDRKSQQAMRDRTKWTIFNLNEQVAFLTQMLSDRARDVNLLNSRMRMLETENSQLRAQNAALQLSLMGSQPRGVDISNDPAAAAAAAAAASAAAAASALAGGAPGTSNSIGSAVSPAGEGSVSGRSGSVATLPEVIKKPWEIPPVDGPPTCLSDQILQGFITSKVHQRSVDGALAFNFKPNLCSLLEKDRRTSDAISDIVGDIVRSYFEIDTLPKQVAVFYIMCSLLKWMVLLDKPSWDLMPTWLRPTRAQISTPHAAWIDRIPWPNVRNYLISHPEITLDHFAAVYSTSFSIRWPYDPTHVLLKAVAPGEDVTINPVYEEHIRQLSNWEVGKAFRDRYPDIGDLIDRDATIQNESTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z506</accession>
    <name>A0ABR3Z506_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_005190</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168819" description="xylan 1,4-beta-xylosidase" evidence="12">
        <location>
            <begin position="17"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="13">
        <location>
            <begin position="522"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="974" mass="105890" checksum="D1C4547A36F67F05" modified="2025-10-08" version="1">MRTTVVLSALAASAVGFGFDPPGQRPLTGSEIHLAGTTHDTDKATAKVAFIESLVANMTVEDLVRQLHLMFGDNLVGPKADGKQYDRTMRFIPNSPVGNIHDLYSLNKSHHNELQKENLEKSRLPIPFLHFGECLHGVGSYQQQSMFPQPLGLAASFNPDLVRRVGRAVGSEARSIGIHACFAPVLDLGRDPRWGRTQESWGEDKVLTTHMGVAFSRGLSKDGSWSDPDAVVPVMKHFAAHGSPSSGRNTAPYVGTGMREIMQELMMPFQAAVELGGVRGVMMAYNEIDGIPAAVHPLLYAKLKEWNFDGFVIADDTAVQELETVHHVASSPSDAIGQWFNAGGMIQFYDYPLEVFLNSTQELVANGTVAQSTLQAHVRTILGVKWDLGLFEQPFISEDTDPLPLVDENSDLVLEAAHKSIVLLKNENNTLPLSRPDRETPPKIALIGPFADTLNFGDYSGTWGQTPAVDAITLREALLKYVSTNEDGRPKNTQLLSSWGADSWEYVSQNVIPPCLLSTPDGMVGGLEATYYPEVDFTGEPVILSDPQVPALDWGIFPPEGLPSANFSAVWEGTLTSPVDMITNGWIGVAVGPYSVATLYIDGENVVISGSGDSLSTPSTILGNILPWSFVGNQTSSDGPPGAAPFTFYPNTSYYIRIEFQTWGNLHELHENIASLRSQMLLFWNLVDQGGGGNGKTKAVQNALGLAEQSDVVILAVGSAWNSDGENADRLSLDLPPSQEALVEAVLSDSTKPVVLVLFGGRPLAIPQHYKRATAVVSAFLPGPAGGQAIADLLWGTVDPGGARLPRDVPRDIGQLPVRYDYKPKSKSAQYVDAAREDMEPYFSFGHGLSYTTFEVNNFKPSATTFTAGDNISFSADIHNTGSRLGSFTLQIYLLSRISTVTQPVRQLVAFQRVDDLETGEKSIINLSLEVDRFLRILDRRDQWVLEKGVYEFAARAHGGDDAEEYGRVALTCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z560</accession>
    <name>A0ABR3Z560_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="578"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="615" mass="66103" checksum="115CB4F67ABD3518" modified="2025-10-08" version="1">MAAFLEDPRLRQRWNQLSHNAETVTENAAAGIWTFQQSYVNPCLASLGEAIDSCTAPCLGDREDRARRQRERARGAHRSRAEYSFDFYDDWYDDFNDEQGAVGDQPEAERGGGGLFGSWRARSADWDRLLAGSGSTRNRGQHHDGADEDDENAGEAPGDGGMSSGDGAGGSGEVTDQPRRGRGMSYSTRAMRRKHPQEDDPTVIPSTAPLGFLSRLPWKIGGTLRYKPSAANLREHPNSSASGGSLQQNSMGGRRLGGGADMMRARDENEPLLGGGGNDDDYQDGTGTGSRRGLLSWQSELEAADASRQYGTALSSVPATRPTTRGTVGDHDEYYDDDAGTTTTRKRSGTTSSGDTSNSFRSRGDLFPSDEEDDEDAVPLDDEFAVALNHVDDRSSGRTRFSSSSSLAATGAIEQQQRKGKKRADTGASTTSVTGGAAGPASIKGVLTRSVSRTTIDSVAVGSSPRSPPSSITNRLSSMSLPLGEAFDEPVDEREETGGAVEQPTELTAEQIREEDERAAREEDEAIEKRREAAARLAKERGLTEAEPTELATADKVDETNKTVDVVDKKNDTVEAADATTTATTDSTPAYSPYTLSSKEAREAEFVPARLPRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6U0</accession>
    <name>A0ABR3Z6U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540142" description="Peptidase A1 domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="67"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="556" mass="56217" checksum="D1986BF6515CBAB2" modified="2025-10-08" version="1">MASRISCAVALLLATNHVLATKSLLPRNNKGPLAFSLSAETAQGQQINGLSRRNADIPLTNLSTIAYLVTLSIGTPGQKVRVVVDTGSDELWVNPSCNSSTSASSGRAGNGVGSNDQNECLASGRYDPAKSSTSKNLNKHGHIQYAKGKVSFDYYNDTVSQSDSGVTLNGLQFGVARKSEDMSEGILGLGFAENHNYTTFVGAVAQQGAAGGPGKVFSIGLASANQANAGTLVLGGLDTNRFTGPMMGVPILPPPPSDTLVRYWVKLDSIGLTGSTVKSSSEGDGGVVSSGSDTSNKTYANSGGPIVLDTGSTLSILPFVVMEALAKDLGASTMQNSRAEFAKLTGRAPDTTASASIFPVPCSSLGLGSDVHSKENQAGLKRTVDFSFNNGAARIRVPLSEFSIQITDNLCCLGGISLDDGSSSSSSSTGTGIPDPASGVTLLLGATFLRGAYVVYDQTASSVFMAPYATCNGGTANLQALASATAGAAGGFTGACSAADSLVGGGAGGFAAAAASASAKGESDDSKKNAGLRSSNVSTSSLVAVFVPTMLMLLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6V4</accession>
    <name>A0ABR3Z6V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16027">
        <property type="entry name" value="SGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF53">
        <property type="entry name" value="ENDO-4-O-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="496" mass="56266" checksum="8B61D5E71F820F15" modified="2025-10-08" version="1">MKNILLIIADDLGRNLGVCGETCIKTPNLDKLAAQGTYFDMAFASTASCSGSRSVIQTGLHTHENGQIGLLRGFTGLHYFTTFDHVESSPKLFNEIGYTTGIINKVHVGPDSVYPWHWREESATRDVAWTAERAAAFFSSVNEDPDKKPFFLTVGYIDPHRDHTRGGFGNFKEYPGIDHLAYDPAEVQVPEFLSDCPEVRQELAEYYSAIWRMDQGVAMLLAELKKAGHEDDTLVVFTSDNGPPFVNSKSTLYDAGVHLPLIVKVPGAKPGVINPNMVSFVDILPTFLDWAGHAELNDKPKAQWGGGHPELELNNKRQGRSFLPILNETTTLPEWDHVFGSHTFHELTSYYPTRYLRTRRYKYHRNVAWQLDFPFPGDLYGALSWEGMRNSEEAKIGQRTIANYIRRGPEELFDLEADPNEVNNLAKDPAHQEILLDCRKRLEEWQLATEDPWYFRDGISTRTIYNHIDAGMKMPDRFDFDVDNPASRDGVISRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8T3</accession>
    <name>A0ABR3Z8T3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc cluster transcription factor czf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CZF1</name>
        <name evidence="8" type="ORF">Sste5346_004398</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="611"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="618"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="833" mass="90538" checksum="B36700A8623FBCB6" modified="2025-10-08" version="1">MGDNFDSRRASPVKTRRSRRGCLTCRQRKVKCDETRDVCRNCFRLDARCTWETPGDNEPGRRRSRNWRACARCRDKKLRCTAPSSGPGCGQCLKAGTTCDALSSVTAEVNTALGVTASDGSGSSSASRSAPSKENTSDIVPRAELLRILDAYFDGPHYFCYSTFLHRPSFMKMLDNGLIPRSLLLIVLATGLQVMGASAGNLERSTRADAWADESRSLVVLDVFARISTTNLQTLLLLQRYEWHRGVHLGAWFLSGVAYRLAHALQLHLEPADVCNNGDKVKLPPSVVETRRRLIWSCYVMDSIPDAHQSGARPLQGALDPSVIRSRLPCDEVQYERGEADRDDKINNPSISAYLIRMAILRKRILTYSGSMRTAAVEREESAAKHGMDIDMDISGDHRVWPWHDGSEFHALKQQLDGLAADLPVSFQLRSHASVPHHARTAFYTLHAMFHAAYTDLLRIGTFVARHMPPVSGVGRARRGSVVPPPAFVHACKVEQLKHACGIAHVVQQCLQSLPSEHDPFVAICSCLAIRILVMERWRESTIGGGHAIGADAKEVLSWDDARVKDGMAACLECAKRTARWSMPIRKLLLAVGDLARQYGHLLDLDEFRPPTQRLMPLTPPPVSRGPPPRRPTSPNLRLYGTSGSIQRARDAHDREVVQSVEVVEKSRSISEAGFDEAVTAAATTLAHPVPQPAYSDTSVRSSLSEEALQIASNWADGTYDVPMAQTNFDWGTFEFGMNFVPIGDVNNGNGIVGGGIAGQQDGLQGGISGGISGGISGSLQGSIPGQKVPDVLNIGVGGGIGTGLSAISGLGVPGVEFGIADGEGLDLHFGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8U6</accession>
    <name>A0ABR3Z8U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61261" checksum="8B072966864B1A1D" modified="2025-10-08" version="1">MAMNVSLPLDIWWLICEELTASRDFDALYNFARVSKTMANFALPNLYSIYELASASADDASIIGKRKLAILWRAIILSSSGKTAFPYCLWMQNLKLGDFKELLSDIAPNNDLRQRFFKGDMASYEMMLQSTAANVATRRNRPRLDLQGIINKVGDAVTLFVKEAADRDNRAVALTHLEGQLLPRDLLPSWTSRLSTLMSLHTQDGSVIGEKVAKSIRDNCPKFRELRCFYCNGPTVDEDLAAFFRTISPNSLEVFSVSSQNHMGKEALQALSLHSSSLKKLGLSGLQSAAFEHLGSLRECVSLESLELEANRGTAAEWESIFPESFADVAAWLSACASMTSLRLWHVECAASLLKIALKAPELQLVSLDLNLLDGNDELYVSLGKQAALKEFYLRSNDVMLDSASPQHAQFIKSVCKLEKLRVLDIMQTTITEDDLDSISVALKNLEELSFDGEAMGDTILTPILLMQKLKSISINASTNFTVEGLLHFINTVGELHEFKCGLSLSIMNQSLEAQIYPDEEKFLSNQAHDTFGGKIDIAHPEEYHESDFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z957</accession>
    <name>A0ABR3Z957_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF129">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="59"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="439"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="627" mass="65643" checksum="9AE5BC8FADA35FF0" modified="2025-10-08" version="1">MTVYEEAPEASTAAAALSVDHHPVAGLPSDNPSTSYWLQDPSKVLFGHRTTEELPAEVDVVVVGSGITGSFAADALLEGAGDSSSSSPKVLLLEAREACFGATGRNGGHCQPMVYSSAYDVSDFELATFHFLERFVAEHDVPCDWRTLPGGGVHAYLDKDLFALAEELVSTLREKRPDLADQITVVKADDTAEGKTLDDLRLRGAAGALVQQNAASVWPYKLVVWVLERLVEKHAASGAFNLQTNTPVLSVKKDASSSSSWVVETPRGKVNAKAVLLATNGYSSHLLPRSLADLVVPVRAQIAALVPPSSDTKVETSRTVESAPAGVTSSSTSSSSSSVNDASKSSITVVETKDGQTTTTTTTTTTSNAPADRLTHSYVFVGHDRGQARGGNRDEYLVQRPFTSGSSGRLVPATSSAQSSSGNASASAFSSSSSPSSTSGGHFIWGGGRQRAAGAGVGEWRDDEVETPVAGYLRSNLAPVLAVGGDDSNGEPAAQLEADYEWTGIMGFSRDANPWVGRVPSEESGGDGLYLAAGFTGHGMPSTSLCGRAVAGMIKRDLGYDAAAGDADKVVVTLPLQAGGHAELPRSFLLTAERIQKARETCEPVAAADTRGFLAEFQHLLAARRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9P3</accession>
    <name>A0ABR3Z9P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="317" mass="32943" checksum="594929E79C0139BA" modified="2025-10-08" version="1">MSVKDRVAIVTGAGGGLGREYALLLASKGAKVVVNDYGGSLDGKAGTIARAQTVVDEITAAGGTAIADGHDVSKKDDTKAIAQLAIDTWGRIDILVNNAGITGRTSPIDDLDVDAFMRVLEIGTLGAHLMTSAVWKAMAAQKHGRIVYIASDGILGFGAGGDCAYAASKGANYALVRDLGRYSPQFGIKINALFPSASTRMTELSEGAKFITSTFFAASTCAPVVAALVSDECPVSGEGFTAGANRSARMTMATFPGHTQETTAEGYLKNWDAVWGKTEDAYVPTGTLDHVRYGVLNATGQELKVEDIPGLGVLSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9V9</accession>
    <name>A0ABR3Z9V9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MET6</name>
        <name evidence="15" type="ORF">Sste5346_004484</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03312">
        <property type="entry name" value="CIMS_N_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003556">
        <property type="entry name" value="PRK05222.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30519">
        <property type="entry name" value="5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE N-terminal" evidence="14">
        <location>
            <begin position="4"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="13">
        <location>
            <begin position="435"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="388"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="397"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1896850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="767" mass="85636" checksum="6630FC72290EC12B" modified="2025-10-08" version="1">MVQSSILGFPRMGVNRDLKKATEAYWGGKISQADLLAEAKRLRLAHWKIQKDAGVDVIPSNDFALYDQVLSHIQDFGAAPERYTSAGLDPIDTYFALGRGHQKNGVDLPALEMVKWFDSNYHYVKPTLQDNQTFSLVEKPKAVAEFLEAKEAGIATRPVLVGPVTFLHLAKADRGQSVDPIDLLEKLLPVYDALLAQLKEAGAETVQIDEPVLVFDLPAKTKAAFKTAYEHFAAEAAKLPKLVFATYFGDIVHNLESVPKDVYAVHVDLVRNPEQLDAVIGALGPQTVLSVGVVDGRNIWKTNLKRAIETVETAIQKLGKDRVIVATSSSLLHTPHTLASEKKLDAEIADWFSFAVEKASEVAVIAKAVTEGPAAVSEQLAANAKSMQARATSSRTNDPKVKERQAQIKPADYNRKSEFPERISQQQKKLNLPLFPTTTIGSFPQTKEIRLSRNKLTKGEITEAEYDRFIEKEIDENVRIQDELGLDVYVHGEPERNDMVQYFGERLDGYAFTTHAWVQSYGSRCVRPPIIVGDISRPAPMTVKESKYAASVSKKPMKGMLTGPVTCLRWSFPRDDVHQSVQAEQLALALRDEVVDLEKAGIDVIQVDEPALREGLPLRSGKEREAYLDWAVKAFRLSTTGVEDSTQIHSHFCYSEFQDFFHAIAALDADVLSIENSKSDAKLLKVFVDSAYPRHIGPGVYDIHSPRIPSEQEIRDRIEEMLQFLKPEQLWIDPDCGLKTRQWTETKAALVNMVNAAKAYREKYTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB31</accession>
    <name>A0ABR3ZB31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="325" mass="35462" checksum="00008973CC1615C4" modified="2025-10-08" version="1">MASPINVAVLGATSETGRSVVKGLINSTEPHYNITALTRPSSVNKPTLLDFQKQGVKIVAVDLDGPETKIVEALTGIDVVISAIHAGHLMDQIPLANACKAAGVGRFVPCCFSTVTPRGVLNLQDLKNSVLDHIKKVDIPYTVIDVGWWYQSTLPRLPSGRTDYIASPSEPCIVGDGNVSFALTDLGDIGLYTARIVGDPRTLNQSVFAYAEVKNQNEIYLTIEELSGEKATRKLLPAEVVTSTIADLVAQNPPQGTPDFFKLAVFQYWNTWGIRGDNQPENAKHLGYLLADELYPGLKGRPFTEYCKEVLEGKAHQVYKDVTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB60</accession>
    <name>A0ABR3ZB60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046067471" evidence="1">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="189" mass="18912" checksum="19312C2EE0DBA0E8" modified="2025-10-08" version="1">MRLSSFQFLLLLVPAALASQNKRQATTTTSALNLQAEAASLVSIYVPPTAYAQLTASVASAASAASVTGDPASLFLSAILATNPPAWLNSAVPPYYSSNIAALESAVATLRSEAGTNTLVSTSTSETLVVTQTTNSLGSTVTTSFTSTFPVTSTHTTSSSGNAAAPTAGPQQQAGLGIAALALGLAAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB88</accession>
    <name>A0ABR3ZB88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="58659" checksum="5491585C10B7C7B5" modified="2025-10-08" version="1">MDTIVSVAVRHLPTIVVVGLVIIGRYFWPRIINYVHFSRIPVLDKAYDGKPEHFMFHSASMYEEGYKTRRNDVHRIRTPDGDHVIIPNAFLDHLRQKPDEQIDVTTAFMKLLENDYIHLFPSHHHTHIANSVVKKELTRSLVKINPALSKAVAETVAEVLEDASEEWTPVTIHTRLLRIVAIVSGHVFVGPDLCRDPVYLDAAVNFTTDITAAVPAVKRWPWIIRPLARYWEPQLAKVEGHRARMRAFLAPVIAERQARKARGDAEMPSDTLQWMLNNTEAEGITDVAVITNMQLLLTMAAIHTTTLTTTYILHDLVQRPEVVEACRKEIKEVLAASDSPDEMTTHALFNMKLVDSVMRESQRLNPPFLDAFRRYTLKPVTLPDGTYLPAGCIIEAANKPVLLDPELYPNPTTFDPYRFVRLRTDPDAPDPLGFKNREQYQFVSITKENMSFGFGRHACPGRFFAANEIKLILANLLLNYDIKAMPIKDGKDGNIGVGGGPDPTREILFRRVKKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBE3</accession>
    <name>A0ABR3ZBE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003913</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1076"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="337"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="390"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1079"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1109" mass="122864" checksum="02A1384CE3B082EF" modified="2025-10-08" version="1">MESGQELRTNNSHGMYQCSQCSRVYNRVDHLARHVRSHLNERPFKCDKCHKQFGRPDLLKRHAQSHEAGGSIKRRRTTGPHATRVLEACLACAVTKAKCEDVKPCSRCRQLRIECEYSGDLRFSRTSGGVLPNPPAGHTDKEASVPSVWTNPELPAMPNQNNHAASRPVSETPGRNLLTGVDVATEYTETQLTGESAAGAPVSWNPFSDFLHGVMASSNFGLLGTYPQQPPPPPSWPRADFGIRDVLDFNISDSSNTDAAHTFNSLLGAKTLYPDHLEHIPTATITVTETAAAAAATQSPPPVPPPLTRQQQQQQQQQQQIMLGRMQGQHHPHQHQNQHQQQALEEAQRQQQQLYLAQEEAAQCSQQRHEAEDRQLQTRTHEQHYMPDLGGDEDDEDDEDDEDADEEEDVDEAENDDEDSSNSNSNHSNHSNNNSSNSNSNTATTTIVQRPESRAGVGTQAFQKSSFSRWQPAKQDHMQAGLDNLSILRNDPATPDLRLVLERRLVCDPLETSTRDKVLAMILTTCDAERAAVVAGAFPHSGLLDDMVQNFFAHHQNTASSCIHRPTFFPNSEPPELLGAIMAYGAVLSDNREVQELGLALQEAVHIALPRKCKLANSLTRELWLLQSFMCELEIGLWSGNRRKTEIAESHTNVLFTMLRRAGRFRSCHDSRAPGPPSADATGPALQRLWLEWAQHESFKRLCFRAFLVASQSSMSLLGTPLITCAELRLALPAPQELWLAEDADKWKAAFLRIQEEQQQQQHTSQLKPRTVIVVRSLLQQPLELASLPGRHDLLLSSLVVLHSLWGMVWDFTQSASILQVDPTHSSALMMLRHKDLCQVLDLLSAGMRGFDALDCPEVALTANLLSMYLHVSLEKIQQFAGKEDMDEARQALPWLKWWVDTTEARQALWDAGQVIRSAKRSPSRLLRGFYAIAVYHASLVCWAYGLISQGTVCRRRGAAACSAVTVMQQGDAVCLDGPETIDTQRFIKTGQGIPSMRSVNRDADMNYGAVETVLVPISDPEAVMGVVIRILKDNNLPAAATYNDNNSTGSGGLPALVENLVQLMLDLGMAGASVMKRQQQQQQQQQQAGLAPPHMNHAGGGEISEVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBE5</accession>
    <name>A0ABR3ZBE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF1">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="197"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="835" mass="94414" checksum="806FC4F058285106" modified="2025-10-08" version="1">MSDSEESGSDGRNEMDDGRGHAFVDDEAEESGEDAGTEGDDESGSGFVTEEDDDDEPDLESERRNIFNLMGPRIRGEIPSDLDDEDDSEDDSEEDEDDEEEDDEDSAGIDDERRWEQTTQRLMDLASYADFGEDDYPDSSDIGTDYDFGAYDSDDSWDNTVEEDPHGNITTHLNIKKMTKRLKFFTGREKYPGTRSFPKFTQLPAELRLRIWELYCSELQRKQRVIQVYMQRHGRLTPAVTMDQQTKAVRRLMSICHETREMGTKALPDVLPVGHSKHDKAVIRFNAETDLVHFLDEHPFGLNAVGSSDTDENPWNTSGPMARERDVALNKQKKNHDVPEPYTNVRNLVIGDMLQRSREPGAYHDHHFGHSHIELVSSEDASHRRPEELRGKIYEDSIKYLFPNVQNIYVSEDGAFRRSDKWAGHLRSYQRYHVRAYEVNEYGDGKQGVEYLYLWHAPPKEPRRRSHNAITNGAEDEASSSKEDEQKEKEDKSEAEATGEASAAGESADNNAANGENDENDENNEDADNNDDDHNQPKYPEIPGDFKDGVVINHFSSMREKGVRFSRLLFFENEGLDDYWDLQKGCRPDGSWPNNVYGDPEQDQMPARYEEDEGHGGAWGEFDDEEDDSMIDDDPIDSSDEEDNSGDSDEWEEIDEEDDLDGDDDDAPPPLAAMFSSPEPEPEEVEGAAETQVSRGKKRRVVSDSDDEDSDDEDAGPAAKKSKTSAGLSKRQRRTVNVSSDEAEDDDDKKDNKKDKGDESSSHTEAGSDSDDDDEDEDDKPAKPLTLMQKLAQGRKSNPISIDDDVEEDEDDEEADEDAGDYGEGDEDEDDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ6</accession>
    <name>A0ABR3ZBJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="52"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="232"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="623" mass="68094" checksum="896853342632AC22" modified="2025-10-08" version="1">MSILDSYPEYATTASLDDLRQTEYAYLDEQKHVYLDYTGSGLAARFQHRAHAQRQASMVLGNPHSVSPTSECATELVEATRTAVLEYFNASPDEYAVIFTANATGAARLIGEAYQYGAQGTAKRGVSPRLVISADNHNSINGLREYARRQGVSTEYVPCRTPDLGLDERALLDILGPEMPTKPTKKSKSSATGWSKFMSSVFCGLFDEREEENMDEKDVEEIDTSTTSFDHSHERGMFAYPAQSNFSGARHSLKWVAEAQRRGYDVLLDAAAYLPTSRLNLNEVHPDFVLVSWYKLFGYPTGVGCLVARREALSRLDRPWFSGGTIRAVSVGLNWHAPAHRIEAQFEDGTVNFQSIPDVKVGLDWLTTSVSDDMNRLSAISIRVRCLTSWFLDRLVVLRHSNGQPLIHLYGPDHCLLDGSNRGGTVTFNFLDTDGEIVDERIVAREAAVARISLRTGCFCNPGAGETALGFSTQDLLVLQALAIKSRPSKDAHDVTVTPFTAVGPADSAKDLTRTDSKWETVNLDTNNSTTTEITENNDKDRSLSATSQSVVSTSSSTSSTTSLSTATSATTAGDDWPIAGAVRVSFGVASNVADVDTFFAFARRVFRDRAGDNSGLGSRVEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC78</accession>
    <name>A0ABR3ZC78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-l-rhamnosidase c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF1">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="60314" checksum="B00A821F60E25A99" modified="2025-10-08" version="1">MGQPTEPSSPLEPFPAATVSPGIEMSTVSADQSNNNFGSFGNIDYSKGTSSNKNTNTNEPSSPSSPADEPIFSDRRNTVGRERRESIAALNSNPNQRSSDSIPRRLSKSFQESNLPPGFMAATADMTSTVMTAARSRSSTARTRSSTTSDPDERNRPLQNQRTPSKGGDGTLETLDEQKHFSASYANGINNVDVNNNNPFGTYGANAATEDAKHQKEGAAPNAAVHPTMSAAGTELSADGAPHRNGVAGHGNSAPANVLADADLYNDYDNGYHFPPKYSKGASFRHGAIAFWQYSKTPLGFFVVLYGLNIVAWGGMLFLLLCNASPAMCHPTCNDINSPRRKWIETDSQILNGLFCVTGFGLAPWRFRDMYYYLQWRIGKNEKGIRRLAGVHRGWLRLPGSEDLPITTGPGNVPAETPCSAIPFPESKIPDKPLTGERAPPTRHWAIVFVLGMNIANTFLQAILAGFMWGMNRYDRPSWSTGLFVALGCCAGAAGGLGMFVEGKRVKGIEGVPLTDEDRAKLAHDRELGIYHYNNLKGKKPKEKDHHNSDLEAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCR6</accession>
    <name>A0ABR3ZCR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489:SF1">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="423" mass="47781" checksum="5BD7AC49011B3570" modified="2025-10-08" version="1">MADASPFRQYLPDLALPRFTTMKAQDAHEYAKAFMEGGRPPWIHGLWKHWLSLFAEPFKGVTSDGKVRDGLFEIEDEGVPIDEIVAAANGVVSLLSAEQKKATLYHIDAPEWRTWSNPEFLLSNKGIRLDEISSELREATLKVLAASLSPEGYDKAITAMRINGFLGELVESPKVMNEFSYNFALFGTPSTTAPWGFSFYGHHLCLNIFFYKTQMVLSPWFTGAEPNLIDAGPYKGSRILTVEEAVGLELMQGLEPEVQAKAQIYKQMRDPGMPHGRWNHDDQRHLCGAYRDNRVVPYEGVVVADLPEASQQLVTKIVEAFLSYLPASVRAKRIAQVQKWYKETYFCWIGGYGDADPFYYRLQSPVLIVEFDHHSGVFLNNAEPAKFHIHTLLRTPNGGDYGMALRPLIPGREQGFLWEGERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD41</accession>
    <name>A0ABR3ZD41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF410 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="36477" checksum="B5590024C994B1AB" modified="2025-10-08" version="1">MATRGDKIEKIIARMQQRISEGQYYEAQQQTRVVAARHIKASNWKAAIDILYNVAQALLKAGQGGSGGDLGIFLVDVYKQAELKVDATSRGRVLTLLRLFDAEEPTRKKYITEAVGWTSKYGEYPAGDPELHHVIGSLYADEHEPYEAERHLLTGTKDSPAVLGRMEYSWYKQDDAHTAPQYAARAVLPYLLMANVRAANESFMVFTTALTADNLGLSVQDVSSASADARVFPSLPLLNFLSLLLLAVQRGSPELFRQLSTKYAAQLKENESWSDAVETIAEMYFHIQRPRQSNPLFDMMGSLFGGGAGGGGGSRGAKGGNRTIEAPVAEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEF2</accession>
    <name>A0ABR3ZEF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="9">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="9">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="9">PHB:PPT</shortName>
            <shortName evidence="9">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">COQ2</name>
        <name evidence="10" type="ORF">Sste5346_003756</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="419" mass="44454" checksum="39692B68532CC80D" modified="2025-10-08" version="1">MRSVCFRGIRTLQPGCLSPRRIALGPMPLKAGQIIYASLSTGRSSWKSSGVPVRASTVRISGPPALARIHTTAVVSSAAATVTATTEAPSPVPYIPPTTGLLSVLPKSWVPYAELIRLDKPTGSYYLFFPCLFSTLMAAPMVEPAMASPASVAGTTLLFFTGAIIMRGAGCTINDLWDRNLDPHVTRTRLRPIARGAVTPFNALVFTGAQLLAGLAVLLQFPTSCLFYGIPSLALVAIYPLAKRVTYYPQFVLGLTFSWGAIMGFPALGIDLLSNSAALAASAFLYTSNIAWTVLYDMIYAHMDIKDDAKAGIKSIALKHAAQTKAVLMGLGAVQIGLLAAAGVASGAGPAFFVGSCGGALATLGIMIKRVKLESVKNCWWWFVNGCLLTGGVISLGLSADYLVRYNKQRTEEKKKIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL8</accession>
    <name>A0ABR3ZEL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbohydrate-binding module family 19 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005089">
        <property type="entry name" value="CBM19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03427">
        <property type="entry name" value="CBM_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046226539" description="Carbohydrate-binding module family 19 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate-binding module family 19" evidence="2">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="147" mass="15428" checksum="BE7F462E86962CE9" modified="2025-10-08" version="1">MKYSAALLAVAATTVAAMPSFSAAANAKRDQCTFGTYACLADGSGIQICDIEGNWELVGPCPSGTSCEDLPQNGFDLPFCTSTPSKKTKRGDDGTTGYDWCPTPGQYTCDGWNAIQVCNTTNGLEKVGDCPSGSHCGYINNIPFCVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEM4</accession>
    <name>A0ABR3ZEM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycolipid transfer protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="203" mass="22711" checksum="A3D4C660F9C9D5A2" modified="2025-10-08" version="1">MSADGPVGVTFVDTLKKSFVDVPIDAEKNIETESFLEATESLVTIFDVLGPTAFKLVKDDMLGNVAKIRKRQLEAPGDSATLQSLVVNELKTKKHNATEGLLWLFRGLQFMYEALSRNLASESEELSASFNAAYGDTLSKFHNFLARGGFKLAMSACPYRKDFYAKLSPNYADLKVKLQEWLDALENIVKILKTFLESKEAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEU1</accession>
    <name>A0ABR3ZEU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RecQ-mediated genome instability protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_003130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049363">
        <property type="entry name" value="RMI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790:SF15">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21000">
        <property type="entry name" value="RMI1_N_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01161">
        <property type="entry name" value="DUF1767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RMI1 N-terminal" evidence="5">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="4">
        <location>
            <begin position="82"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="253" mass="27077" checksum="8A16E250BA943D6F" modified="2025-10-08" version="1">MSQALQIRSALAAEQLPAPSQAWLQSVISQQPAQQRSLPALVASAKARLLATDLTASGMFDSASQPPGFLREVLSPQAASVQETRLAQDVVVQVVDMENLSQSRWQQVQALEAIERGEQKRGREIIRIPVGGEEGGEGGDEAGAESSRPGTGRQLASAANNAPSDAFSTHRLVLQDAAGNTLFALELTRIHRISISRLHIGEKLVLKAGTVVARGTLLLEPASIKFLGGQVETMHKTWLDGRLKRLREAAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGK7</accession>
    <name>A0ABR3ZGK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002719</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="64671" checksum="271BD4B47A751654" modified="2025-10-08" version="1">MAFSDLSAIAIGLGTLYFILYRLQLRRSRPDEPPVIPAPGLPFLGHVLCMALQGGRYMQQLGLRIQHMAQGGVGTALGGPTPSAVSFPSSSSTSSQAPTGIVTLPVPGSRIYLVTDPSLAAAVQRASRAMSFTPLVPDVTRRVLGLDEKTVGIVRGENLAVATSPKPRPAATSSTGPTMSIVDDQKYDESYGFLADMHSMVYSYLGPGDTLTTFVKDAVGELVGQVNSYASGLEASTISTPTSPVVDLLAWMKHFVTFGTARFLYGPHNPLAVEPELEPAFWDFVHGLGRLLLVGDRRPGSLMASLLGGRPFAARERLVDGFTTYLTADEHLSSDSSEIVRRRVAIADRYGWARASTARSELSFLFAGIINTAVTSFWVVLRLFSNPDLLKTVRQELKQGGDDNSDGDTLSIEHIRTGCPTLNAVYQECLRLGSNNMSTRLVLSDTMLADRYFLRAGSVVQIAAGVIHADPSLWGADVDTFDPTRFLPKTTSKTDKIPEKATSTAPKRHPAAFRAFGGGKTLCPGRHFATAEILSFAAAVVLTFDAEDATASAKGQHGVPPKVPPRNDRVLPIHILEPAAKDVPQVRLRLRRPGRALRVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGL4</accession>
    <name>A0ABR3ZGL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tpr domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24145">
        <property type="entry name" value="Mgr3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="62769" checksum="02C5812B08773B9B" modified="2025-10-08" version="1">MSQPLATTGAYRKICRTAGPFVLSATQRPLACRQSISPASVQVDVRVQGPGHSQAQVQVQLVASRYANSLVRTRRLSPQSFKVGSIQVRQLSTTSRRNNAENGQNSQGGRSGQQQQQQQQIPKGRVPIFRLLIRALGGSLRSLFTPFQGQTLRTLYRSNPEELVLALAVLIASVFVVGYVVRIYFTYFNSRQFTRYPPEVAKYLRKALYFSNYQPDPKRALKNYRLALEKCDELGLDPFSEDVLGIRIQLASWLEQIQSYDAAIKILEILLADCRRWADLMEQDEKDAKAGKTVAETSELKPRLPPPLLTGKSAKEAEETGVDMSGDSETVWGRRSRILRKAIGVSVKLGQLYADEHVLNSDKAHERLVWAVDTALAEFQRRAMIGTKDGEGEWMSPVEMGAALESLGHSYESRSQFHLALPLFFQALRVCSDPCHSAVIMNNLAISFAQHPVQPPYETLVGSVIDKPASGREITQQEAQRAYYETAQRWATNAHQHATDTSGDARTAECDEACAVALCNLGDIAALLGDAREAVKRFKEAKAMSQTLEYAPGVQQAEAGLARLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI25</accession>
    <name>A0ABR3ZI25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Insulysin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_002871</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="8">
        <location>
            <begin position="42"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="9">
        <location>
            <begin position="212"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="10">
        <location>
            <begin position="398"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="11">
        <location>
            <begin position="793"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1029"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1083" mass="123633" checksum="86F6E151B94E088C" modified="2025-10-08" version="1">MPSTTDQPAAPAVKLVTEALDKPSLDNRSYRVIELGNGLEALLVHDSETDKASASLDVGVGNFSDDNDMPGTAHAVEHLLFMGTKKFPEENNYNQYLSSNSGSSNAYTSSTSTNYFFDVSARPHADETVSPLYGALDRFAQFFIEPLFLESTVDRELRAVDSENKKNLQNDQWRIHQLEKSLTNPKHPFCHFSTGNLDVLKIEPEARGINVRQKFMEFHDKFYSANQMKLVVLGREPLDTLEKWTAELFSAIPNKHLAPNMWTDVVPYSPEYLGLQTFVKPVMDSRDLTLRFPCLDETLLFDSQPSRYVSHLIGHEGPGSIMSYIKSKGWANGLGAGMYPVCAGTPAIFEVTIRLTEEGLKDYKEVIKVFFQYVSLLRESPPQEWVFDEMKGMADVDFKFKQQTPASRFTSKTSALMQRPLPRERLLSGMNCLRKFEPTLIQRTIDCLRPDNLRITVTSRTFPGDWDKKEKWYGTEYKEEKIPADLVEAIEEAYSVTKSNRIANLSLPHKNLFVPTKLEVEKKEVKEPAPSPRIIRNDALARTWFKKDDTFWVPKGTLTVSMKNPIIFSVAENYIKTNMFTELVRDALEEYSYDADLAGLLYNVSLEQRALVIEVSGYNDKLPVLLEQVLITMRDLDIKDDRFAIIKERATRALRNYGFQQPYYLLSNYVSWLTSPYAYTVEELAKELPGVTAESMRRFSKELLGQLHMEVHVHGNLYKEDALKLTDMVESTLRPRALPRAQWPIWREVVLPRGSNYVFEKKLEDKENVNHALEYVLHIGDRGDRPTRARTLLLDQLTQERAWDQLRTKEQLGYVVFSGARSGTNTMNFRFLVQSEKIPQYLEERVDSFLTEYADTLGKMSDSDFEGHKRSLIAKRLEKSKNLYQETSKHWVQINNEFYDFEFAKRDAEEIKLVTKADMIQFFNYYIHPESKMRAKLAVHLVAQATTDVTTKQISDLVKDLGLSEEATTQAATDLKARLGTSSQDEAEEEESVRDYLTKTLSAAADKIEAAVDAWKQLSKYHKAINGTETAEDQGISRPKKDPNGTTPVKIENIREFRMGVALTGGPRAITDISEFLDVDAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIB8</accession>
    <name>A0ABR3ZIB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="32191" checksum="0820684B9A562765" modified="2025-10-08" version="1">MYVDGVPNGPEAPPETTEKTQFCLYDVLQFLARLSCTGRCRFYHQPFEKEHGVVQRPELDVHPEHRIHPLWASRASSSGDQTNEAIGAPNRSVNVDATWAETLASGRAAEVTPLSADVRNLFHALAFRFGRTLRELETVERPRWEPYLRHRGDGRSVNNAMQASIRMWHATYQALVNQGGARHEARLNWIPTSFAKVIQYADLIKFSELQAAHGGSGGSPRRLSEAEARAIVQQHNRSDSVWDWAHPSIVGEAPQFFHMQRGHWTCKHQRRPLKMEEVKKMSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJU3</accession>
    <name>A0ABR3ZJU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540150" evidence="2">
        <location>
            <begin position="23"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="42720" checksum="97551C376233814A" modified="2025-10-08" version="1">MFAKFIFSAVLALLLSASPVLAHMTLASPVPFGDPTTSPLNSDGSNYPCQIVGSPSTFYADAASTSANNTMALGATQTLSFHGSAVHGGGSCQLALTTDMQPSASTSWQVILSIEGGCPTTDGTGPSTYDYTIPDSIAPGKYVFAWTWISKLSGAPEYYMNCAPVTITGNASKSKRETVDSGVIEVRDGNSTSSAALPNLFVANLASINSCKTTTSTDPVYPDPGPNVLKPSKMTTNFQSPSGTDCFPLGASNSSSSSGSGSGSGSSSSAAPVAASSAAVPVVASSAAVPGTTLTTLTKSSSSAAAVTTAPVVGNGTTTAAAATGTGGIFVTVSGASSAAAATTAAATTPAAASSATSAAPAASASSGSTSSSGGLSGACTTEGMFNCVGGSEYQQCASGTWTALQAMPAGTKCQDGQSTTLWARSFRRVRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK83</accession>
    <name>A0ABR3ZK83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNL-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="6">
        <location>
            <begin position="102"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="238" mass="25229" checksum="A3CE246CEBE989B8" modified="2025-10-08" version="1">MASRQAWSRLATQPLLTVAQRSAASTSPSFALRHLARRPAPVPAAAPSQASSPITFIRLAHNIPRPKQTAPSQDSETPAAASQKAQLAGSGQNNNSAAQNVGLAPHYELTFTCLPCGTRSAHHVSKQGYHHGAVLITCPSCRNRHVISDHLGIFGNVTKEGGGRTIEDILREKGQLVKKGTLGEDGDIEFWEDGTQSERQTRLAAEDVMLPPAKDKKAKTGAADEAAPGSTFKSAGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKC5</accession>
    <name>A0ABR3ZKC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">M-phase inducer phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MIH1</name>
        <name evidence="9" type="ORF">Sste5346_002322</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MPI phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01530">
        <property type="entry name" value="Cdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000751">
        <property type="entry name" value="MPI_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00716">
        <property type="entry name" value="MPIPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4 6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="431"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="246"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="658" mass="70696" checksum="3CBF1C77129DECD3" modified="2025-10-08" version="1">METSSPLAAMHRPVAPFGKRDLFTNLRVRLSPGKPRSNGRGLNGSGNGGAFSIRDQLNQECFGPVHGSSPAGSLAADLCQNFSIGEENSPRFPTPRRALFTTTCHSLKAPPLVSSSPLPVEALMDMTPVPKKVVAAFVAAETEMQMSSMSSPASPCPTTNDQNDQMMLESPCPPQPAAAAPAPVPVAASIPIALEPSRTLASALERRKLPRRASLTRAKGYSFAGPTRMHSDNQLPFFRFGESRLPPAAPSANSSSLSLSECFQESPPQPAASQPLAERRPQTSHSPCANASAASGSGVGGPIRSRPSFVSMSNAGSASSSRTGSPINGHIRRQSSSFVRPRRQYRRSLSMFENPIDMMKPKRDEGAGAGATAPSGLQPSLLTSVMDTDEAINAPQTPALPHFFPEGQNDSIPRIDRATLLRVLDGQFNDSFDSKLIIDCRFEYEYEGGHINEAINYNDKDLLATHLFRSNPTDGSPAPLECRGRTLIVLHCEYSAHRAPLMARHIRAEDRAVNAEHYPRLSFPELYILDGGYSGFFGEHPCRCYPQAYVEMDAAEHAFACERGMGRLKQNRKGLHRAQTFAFGQHDASPTAACGRGSALGQKPFQFNDVSSPIAPGRSVNSSSLLSLDSSPVPAMALGFGSPILGSDRGHARRMASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKU9</accession>
    <name>A0ABR3ZKU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 10">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_002400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="11">
        <location>
            <begin position="118"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="425" mass="46730" checksum="AEB02F8935F116A5" modified="2025-10-08" version="1">MSSNPFPVANIPFGVISTEDDAQPRPATIIEDTVVDLAILQDLGAFDHIEAIKSARPFCSAFVNDFAALNKWTRLATRSHIQKLWTDGTLAKTYGKALLPASSVKNHVPMSTINYTDYVSSRGHFENIQNMIGTPTAARSPFYHMPTGYYGNSRNIVVSGTPIHRFHGLIADQFQIEKLAITGPSQRFDYELELGVYLCGSNKYGEAISVEEADEYIFGFVLLNDWSGRDIQRAESGGPTGPFLAKSGAVTISPWIVTLEALEAARMPRQQKPIVPFVDHLSEGTSMSDPCLSIHCSAFWKGPKTTGDIDGTKTSEADYSDTYWTYRQLLAHQTFNGAMVGVGDLLGTGTMSKFESDDMGRCCISERTYNGTKPLDIGDGQTRSWIEDGDEIMFRGWVLDGKTGERLFGFGECKGQVLPALLGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLQ5</accession>
    <name>A0ABR3ZLQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF115">
        <property type="entry name" value="DIHYDRODIOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="151"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="405" mass="43875" checksum="ECE5E86DE42D7479" modified="2025-10-08" version="1">MTDTVHTTRWGILATGWMASVFVKDLLSDPAVRGVTDVRHEVVAVASSTSTDRAQKFIDEHGQMIKTTAKAYGSYADLVADPNVDIVYVATPHSHHYQNALLALKAGKPVLVEKAFTTNAAQARELVEEANAANLFLMEALWTRFFPLAAEVREAVASGVIGAVQRVTADSSFGENVEALWGTQNRIINLDLAGGALLDLGVYALAWVFQILYHLQPSPRQPPTVASSVIKYPSTGADEQTVVLLTFPVGPAVDSKSEGQNNSTQGIATCGIRAGMDPDQKGTAGAPIRIQGTHGEIQVFGPTFRPTKYRLIPKLDTNTGKPVGPLSEVKDVEHVIPGPGERNGGHGMYWEADEAARCLRDGKQQSATMDWEETIVIMDIMDSVRKQHNIKYPNSIETTDYPVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLX8</accession>
    <name>A0ABR3ZLX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-homologous end-joining factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_002101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the XRCC4-XLF family. XLF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22285">
        <property type="entry name" value="HD_XLF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.10">
        <property type="entry name" value="DNA double-strand break repair and VJ recombination XRCC4, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052287">
        <property type="entry name" value="NHEJ_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053829">
        <property type="entry name" value="XLF-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015381">
        <property type="entry name" value="XLF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038051">
        <property type="entry name" value="XRCC4-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32235">
        <property type="entry name" value="NON-HOMOLOGOUS END-JOINING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32235:SF1">
        <property type="entry name" value="NON-HOMOLOGOUS END-JOINING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09302">
        <property type="entry name" value="XLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21928">
        <property type="entry name" value="XLF_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XLF-like N-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="XLF-like coiled-coil region" evidence="10">
        <location>
            <begin position="128"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="277"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="433"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="571" mass="60952" checksum="2731AF1007E2C30A" modified="2025-10-08" version="1">MDDGREWRLLPATHPDVPVLLVATSFGPAAYSVYVTDLAHVWAERLERRDICMRAFQENTTIDPSYDSEQMGVFLGKLQAALEGDADARLSIAMSPKQEGDLVLHTTSALPAGLQPLKWPIYLKKQSATAIASNLVVPLIQNRAAHQRAEARLVAALQDKDAVINKLADKLEAMGAGVESAFPTLVGGGRGSRKISRRDMEARVRGLARFDETNFRKQMEKEAKKNGADEDDDANKTTNLVEEAFGSGSGLQFDDAAVGTSSQPSSTLENWWQELGTGLGVPMNRTGPAKGSNSQQPANSNDDTMDVDQLPDDGFQEATPKKTKAPRKEIEEAKPVVEEPPSPTPAKPKAGLGKIGRLGAIGKKPKASSPPPPSPPPAEKDDSGDETASDGDDLEPPKTRAAEKEEAKKAAATESDDDKEPTPTVTTASLRTKPAKKGLGRIGGKKKAPTPEPEPGLEPELQQEPEAEAAPEEEPEPKAADSPPPKPAPAKAKGGLGRIGKGKPSAVKKEPTDDGSDEEDTGKRKAAQEEEEAKPAAAPPPPPKEDAKKKAEVLQKAVEKHAAPVRKKRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM48</accession>
    <name>A0ABR3ZM48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S-Me-THD N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="1">
        <location>
            <begin position="315"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="517" mass="55146" checksum="0581B4FC49ECDD9E" modified="2025-10-08" version="1">MCGTSTDIGVLLQPGLTRLAAAYVPVGGVNVNCARRHLHSIGLGDRSIVQQAASDGQVIVGLASVGSKFQRRLIFGGTTTMATNIAVAGGRAHIDAVPVIPASVDSLDKSLVNTTLARIKAMLRQVIDEVKTSPQPLSVLLTGGGFILALDIIESASEVIRPPFFDVANAVGATCSGVGVAVDMIHSTSERSAAGLADEVKKLAIDRAVAQGAGPDSVYIAQLDAITIPYLDNRKRYIVTTIGDLDLSTTTFHKPVDEIMATGFDDVEDEQIFDNREQYELRSVAEEAQVDIKTHTPTVVRDKTTGVAEWHLTKTDIDSLADGCYLLECGGGGNPNAGRLQLRDMLDAGHRIRVIDPTGRVAVADDARVYWGGHMGSLSAISEHLMAHETVLAIRALMGYLRHDDLDSVVGIEFGGLNGLEPLLWGSSLFFDRPVLDADFMGRANPMCWQITLTVYQPGQFCPYEINAGTGHTLLLTRAPKDEDVDRPLRGALSELGSLVGLEPAPTTGSAVRQFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNM2</accession>
    <name>A0ABR3ZNM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="9">
        <location>
            <begin position="65"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="8">
        <location>
            <begin position="312"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="375"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="46363" checksum="98953BE08133EF28" modified="2025-10-08" version="1">MADDATVKQEAGSLPIKMDVDADEGGGLASIPAVGTGGGHEDDIYEDAGDLEFFDATQPGNPFGNMYLVRVPPYVWEAWDKLDDDAEIEVATVRQWTEVDNKTGEPKYRMRMLLRNDLASHQSIPKEYELDLPMVDTAGKRNAANSGSGGGAQNTQIKNTFLFSEQDLPGFKAKNKERAQMAAAGIPAHLLRAKNNDKVEKPPQHHGGRHHYRRQPRQEFFRKAIPKKTTVAGRVRHELNCAPVKNVESDMILNERARAAMIPKAQVKFGDASKPEFRIIGSGGIASQFHATDFIKTAQPPPKVKKVETKTARMPENDLLDLIFNCFARFRFWSMRALRAEIPQPEIYLRHTLEKVADLHRSGRFANNWELKAENRKDGSATAEVKASEYVAETADTDTDGEEEDIKLEDVVPPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNP1</accession>
    <name>A0ABR3ZNP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">20S proteasome maturation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="18689" checksum="357FE272603FECDF" modified="2025-10-08" version="1">MSLRIVPVDSHADSFSHVAARERGAPSAPGVHDLMRHGVGPKVAAPSADLSSKAAAAGTAAPQLDSAHPLEARLKQWEATRENMRMEMLRRTYGVAEPVRRGMELKITRDGEWRPLALGSAGPSSSLLPSVHEDILLGRDTTVDWEDIYTGEETRSVPTFHEEMERKLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP71</accession>
    <name>A0ABR3ZP71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyketide transferase af380 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051411">
        <property type="entry name" value="Polyketide_trans_af380"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="36251" checksum="B3ED63B74107E2F9" modified="2025-10-08" version="1">MPVHGRYTTEKVTYPSHGDTIAAVLFKPTNITNPPGIVLTGPYSFVKEQAPFQYATRLADEGYAALIFDPRTVGESTGQPHRLENPKMKNEDAVAGLDYLEKRGDVDTKRLFLVGICQGGPESLDIASYDKRVVGVASVSGYFRDHETDLYMICAGCVAWSPGVDIGSITMPTPDQAEALYQARLKRAQAAKKKYEETGEVIYEPLVDPTAADPNVGSNAGLPGPLVWSWYGPWTLRNEFDNRYAIMSDVDHFSYTTVPGVAKLQTPALIIHGDNCMNAPAAKRHFESIPTENKKLIWNNEVSHFEHYDKPDAVDHNVGEIASWFAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ2</accession>
    <name>A0ABR3ZPJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HGH1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HGH1</name>
        <name evidence="6" type="ORF">Sste5346_001060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HGH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007206">
        <property type="entry name" value="Protein_HGH1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04064">
        <property type="entry name" value="DUF384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="4">
        <location>
            <begin position="95"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HGH1 C-terminal" evidence="5">
        <location>
            <begin position="283"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="362" mass="41125" checksum="EB00700D5CCE2371" modified="2025-10-08" version="1">MPTELEELVGFIGHENPQIRLLAVENLIPYSTSQPSIFKVNNLEPINELKIIVADHPKIAEHALTNLINLTGDADVLKDVASDEKFLELLFHLLTKKDEVNANLLAMLLANLAKWDGLKAILDRKQDAPEGLGSDDHVINQIMDLFVKGADGSYNKHADYDYLAYFFADLAKHAEIRQYFVKRQVYDDVIPLTKIRVFTEHKSEVRRKGVASTIKNVVFDIPSHPAFLDEDDINILPYLLLPLAGNESYDEDEMLDMLPDLQLLPPDKQRDPDATILQTHVETLTILTTTRPGREMMRAVKVYPLIRETHLRVDNEDLRDACDRLVQVLARDEAPDEKEDGAEESRVTEVEDDADDERIVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPS0</accession>
    <name>A0ABR3ZPS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA polymerase</fullName>
            <ecNumber evidence="8">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_001138</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019843">
        <property type="entry name" value="DNA_pol-X_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF29">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY PROTEIN POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00522">
        <property type="entry name" value="DNA_POLYMERASE_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="101"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="517"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="639" mass="71015" checksum="EB4DA4B53C5D9D81" modified="2025-10-08" version="1">MSQSLTFPSIYLLPGRLPKNKLEELQKQIPSLTTDASKADIFLGKLSNKERAQFELRRLGVSTIEIRKPGARTRSATALAPAEAPAAKRRKLGSRSPSPIVISSSSEDEGVQTVAPPELSLKVVKLAWFTDSVARGEVLPLDDYTIYEGRRFRPEPAAKSPTFSSQVPFADGIWKRAQADAAGGGSQSSQRPPPNSTSPFRSPHRKKFDAVPPIRPSLIRQTTSENDKMQGLPPIPDFLHTTYSCQRPTPLHCPNEKFVDALKTIRVARQLTGDRIGIRAYSTAIATIAAYPYELSTPSDVSRLPGCGPKIAELFREFQNNGGHVREADNDNSDAKLSTLRLFYNIWGVAEATARSFYNKGWRDLDDVIEYGWKELSRVQQIGVKYYDELQDPLTRVQVEVIANRVLQHANNLQDGFQMVIAGGYRRGKELSGDVDIIISHPDESATHLLIRRLVLSLEQAELVTHTLTLSTANSERGQEAVSWKGNAPNHNLDSQSSGGGAGFDTLDKALVVWQEPMEEEDGDNKEKGNEETDDEKRKQNTNPRRRVDIIISPWKTVGCAVLGWSSGTTFQRDLRRYCKYEKNLRFDSSGARSRTDGSMVDLEGFYGGDPAPDMLTAERRVFDALGLEFRPPNERCTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ16</accession>
    <name>A0ABR3ZQ16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="3">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="71" mass="7836" checksum="25CC2FF982661B82" modified="2025-10-08" version="1">MPSYILQFNADTPKEEQEKVKKSVTDKGGKIVHEYSLMGGFSFELPADHISTLDAFPCVQNVEADSTVSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ69</accession>
    <name>A0ABR3ZQ69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Cysteine dioxygenase</fullName>
            <ecNumber evidence="2 7">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_001222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2 7"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="227" mass="24678" checksum="994DCE0C61AD5E12" modified="2025-10-08" version="1">MAISVLPMTAGASASLDRVVDDRGAEDVGRFELLVKALKQALGPSSGLTSDDVDVNHLTRLMEEYDANDEGWMPYNFGDASRGYTRNLVDEGNGKSNLLVLVWSPGKGSPIHDHGNAHCLMKILKGDLTETRYAFPEASASDSTEPQPMIITSEKTYHENAVAYMADELGVHKIWNKGSDFAVSLHLYTPPNVAKGGCNVFNEKTGKCSHVSKCGYYTAYGKLLKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQJ2</accession>
    <name>A0ABR3ZQJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycogenin glucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.186</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GLG2</name>
        <name evidence="2" type="ORF">Sste5346_001182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="792"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="792"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="875" mass="96333" checksum="6381F4F7C80D14AF" modified="2025-10-08" version="1">MALQSGEDIYATLLTSDTYLPGALVLAHSLRDAGTSKKLAVLVTLDTVSAEVITQLKNVYDYVISVPRIKNEASPGKLHLMKRPDLHSAFTKINLWKQAQFRKIVYIDADVVAYRAPDELFDLPHAFAAAPDIGWPDLFNTGVMVLTPDVGEYYALSAMAQRGISFDGADQGLLNMHFKNSYHRLPFTYNVTPSAHYQYLPAYRHFQSSINMVHFIGPDKPWTQGRGASHGGGVYDEMVGQWWSVYDRHYRPVTPPPPEANLPASAPPPEIIHLPWILDARHMVSIQKLYRLLLHPSRFMRTTSTSTSNTPKHPQHKTMITIAKDHLASILTTIIIITTTTTINMTILTVMMNNTNPRSMVIPNMLLPQRPLLLSNRTPRTIIRPLTCPLRFLMREHTLRLEKTRFRVHNRERLNLRRKSKSMSQNDPQWSPVGMLNGMQPPPANAKPEAMNFPQTHYEMSRDATPFVPPPRYASPPRDMWYEVPKAAPAPAHQRPAPIFPWETHRPAPARVFAEPPPPPPPAPEPTQAETHTGQSGYNPHPSFQELGAEPSSMNTGSPSTDLKTEPTTPIMSSNTARDRGLPPSDPWASFTRTNAWDGVPQIERYVDAFQKQHRRVRSRGQAPGGGLRSASGSAGHGWTGSGVGDVSGRGVDNDDDASSTAPWRRGSKVTDFPSEVERPSLPVTPAPIRRPRHWGGGGPSFGADDDEDAAGGDGSSHLLPAADGVPQQVDWDPATQLQKLAKEQSEMLLQKLGDTEGGEGSNSPRTIPLRPLPFSSEDIVSPTYVAQAPPVVVSPKPIKPGGLETSSVRNIDTGSDEPTIPSPFSGNDNNSNNSKIAEPSYLGPGIVFEKDESYPEHEVAAALPSEEELDVLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQQ2</accession>
    <name>A0ABR3ZQQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitin deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10958">
        <property type="entry name" value="CE4_NodB_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF137">
        <property type="entry name" value="4-DEOXY-4-FORMAMIDO-L-ARABINOSE-PHOSPHOUNDECAPRENOL DEFORMYLASE ARND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="3" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="6">
        <location>
            <begin position="84"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="297" mass="33476" checksum="0E951DDBCAA04ACB" modified="2025-10-08" version="1">MLRFPRLLRLPSKLRRRARRQRMATLLALLALVCLLLVPFYVVYKPPRPLISYFVSRWPDVLWRVDLPVVVTSGDPSEKPAQRKLVALTIDDAPSEYTRGILEVLHQYDAHATFFVIGGQVPGRQSVLREALAQGGHELANHGMHDEPARSLTDGDLKAQIAEVDGMLQQVYESVRAGRHGGATNTELAQDKPPRYYRPGSGFFSDRMRSLIQQLGYKMVLGGVYPHDAQINYPWVNAQHILSMLKPGAIVICHDRRSWTAPMLRKMLPAAIKQGYQFVTVTELLEAGKEAPYTREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQR1</accession>
    <name>A0ABR3ZQR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SRP54</name>
        <name evidence="15" type="ORF">Sste5346_001411</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="14">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="530" mass="57262" checksum="3D5AC3FF90864E8A" modified="2025-10-08" version="1">MVLQDLGRRINAAVSDLTRAPNIDEKAFDSMLKEIGNALVEADVNVKLVAQLRKSIKSTVNFKELPPAVNKKRLIQKTVFDELVRLVDPHAEPFKPKKGKTNVIMFVGLQGAGKTTSCTKLARHYQSRGFKACLVCADTFRAGAFDQLRQNATKAKIPYYGSLTETDPAVVARDGVEKFKKERFEVIIVDTSGRHRQESALFQEMMDIQEAVKPDETIMVLDATIGQQAEAQAKAFKEAADFGAIIITKTDGHAKGGGAISAVAATHTPIVFLGTGEHMLDLERFAPQQFVQKLLGMGDMAGLVEHVQSLKLDQKDTIKHITEGIFTVRDLRDQLSNIMKMGPLSKMAGMIPGMSNMMSGMDDEEGSAKLKRMIYICDSMTEKELDSDGKLFLEQPSRMTRVARGSGTYVREVEDLLTQQRMMAGMAKKMGGNMKNMQRAQSAMAGQNKQQQLAAMQKRLQSMGGAGGAGGGGGLGGMMPDMGSLMKMLGGGGGGMPDMGGMDMQAMMQQMGMGMGGGGSPAAGRGGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRI7</accession>
    <name>A0ABR3ZRI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="321" mass="35968" checksum="51A94709BA57EEA9" modified="2025-10-08" version="1">MKDVSNVEPAYLISLHFYAAISMEMCARPLNTPSTYRADLFQQARNHYDRASQLVRDAEESAQSKFRASFSLLSLSSPHSPSGSTSSRAWTSETGLSSPTPSVCSSEDLNPRLHQSHFPSPPNLSSFPKPAPRKKVSFELPKDEPAILEPYIRPDSPTLGFDDEYFVTGLARQDLPRIPTCSKKSPVSGPTLHQAGDDDATPRALRDFYSLGHLSQGPLDVESEFDRRSFQLDKSTSRYCEHLSNLKSRLARHRANLEDIIETPVGEGDIADRSSTPVDDGTRCLDRKARIERLRRSGWQRKRFDPSRYEALRNAALSELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRT7</accession>
    <name>A0ABR3ZRT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pali-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF7">
        <property type="entry name" value="PALI-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="24508" checksum="FE1E8B5CB5A11912" modified="2025-10-08" version="1">MARTGFFHHIGSFLLFAATILLLVTTISSPVVNDISMLKVDLSNSTSEHQSAITFGTFGWCTIHTASGHDACSPKKIGYNPSAVIANADGTDNFSNASEDSTKALTRVMVLHPIATGVAFIAFLLAVGAGVVGSFLGALVSLVAFVITAVVLITDFVLFHLVKKHVNEDGSGSKASYGVGLWLILAAGICLLLGTLVVFFSCCSARLHRSRGTSSGKADPAYVAQPRRRRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRW5</accession>
    <name>A0ABR3ZRW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="10">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IDP2_1</name>
        <name evidence="12" type="ORF">Sste5346_000851</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006156">
        <property type="entry name" value="PRK08299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="11">
        <location>
            <begin position="23"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="425" mass="47376" checksum="282419658D786792" modified="2025-10-08" version="1">MASQQAGLASSAAPIKKIKVVNPVVELDGDEMTRIIWQDIKDKLILPFLDIDLKYYDLGLEHRDATNDQVTIDSAEAIIKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRIPRLVPGWEKPIIIGRHAFGDQYRAKDRVIPGPGKLTMVYTPADGGAAEEIAVYDFKNGGGVAQTQYNTDESIEGFAHASFKMALDKALPLYMSTKNTILKKYDGRFKDIFQELYDTQYKKDFEAKNIWYEHRLIDDMVAQMIKSKGGYIMALKNYDGDVQSDVVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLAQRGKLDNTPDLVAFADALERACIDTVDADGIMTKDLALACGKTAREDYVTTTEYLNAVERRIRTSLQEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY6</accession>
    <name>A0ABR3ZRY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Insig domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="49849" checksum="E39C2E60A13EC976" modified="2025-10-08" version="1">MSNNGPPLVVHQPIPRRPFAAKPSMPSEESLEKDDSRRDERRKPAERAQFLDPQPQTNTDANSTPGGSESISRAQSIMNLTSSTLFGIFSPTTPSRGSIGGGNSGIFESSTPWGTGAGTPARDLLVEEPEDNDEDETEGEHTNASAAEIDEVRKASQSLMMLQRQRRRGESFGADGVSGIKLQPAPAGRTKSISSESAQAAASSSQSRILLFLSLTARAALLFTLGMGYGVLVSRLRSETHVAFDDLGEPTPSPKETGPASEYVASYDWRYLVSWGLSGIALGTLLPWFDGVFDRSFGRSGSVLAKARTAPETDWALVVRGIGAFAGVAFAMRKLPWTSTMQASMTLALANPFLWYLLDRSKSGLLLAAAFGFVGSGALMILNLDLMPNPGMHPSPYHVGYNGGMGGSFGGDSYHQNDSAGHSGGNGNLSASTVTAETAIWMLSVLFCSCVCFGNIGRRLALRPATAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSE6</accession>
    <name>A0ABR3ZSE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II elongation factor ELL N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019464">
        <property type="entry name" value="ELL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10390">
        <property type="entry name" value="ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase II elongation factor ELL N-terminal" evidence="2">
        <location>
            <begin position="154"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="834" mass="91133" checksum="6075F06D05224AC9" modified="2025-10-08" version="1">MSFHVPRTGLQLEEDFTGTYDHLPTQSFILDLSDDVIDGMIESVNQGNEIRLSLGNKPTFIYGNSSYHIEPTFEDETDDIELFLESADTTAKAERLPQLAMSLFRKPELGNPWAHYRNSSSEDEDDDYYEMGSSPEPEDADQESYDALDSDIALLRDSMAQREAEKHEKSTRVIEGNAPAPNGKSTAKRTAGSLQKALSDRRSPFNRSSLSPLPTSPAISNAGSPSLLPTDAASQQVAEKTKQARSPIIHELAFKEQSYDMLWQKYPGSSEADFKTALDKVADLDEDTHNYILRKKFWKELDVWRHDYASDEERQQAIDNAIRQFDKMRLSTTEPEWERLLPREERGQGRILSKVQVSIAKGTSAPKIRVSKADDSSAESGHANHDSSESGNGSGSNRTDEEGGDSEVTLSPSRHTTTGAAKKKLSAREAQEKRLLSTSKKKSPPTSAPAARSTSPNTATTSTKVSPAKSAAARAKANENLGKFKSKEFVSESDTSDSESESAPLSATVHHHPKLAGGSSSSKPSPIGSAKAASAKAASATLPVSKERASSAAASSVRKTTKPSPVKESTQKTLLPPKPPLRKRARDYDDDDSSSSSSSGTPLSKRIKPLKSAAKPSSTLRDARDAREAREAREARDSRDARDARDAREAREAREARDARDARDKPRLSAQPAARTRNVSPNESSSSGSGGNRDKDGGNSSTSNKAKNTSPVKSSPLASSPPTNASELDLSSEESVPPIGTTNTSKKRKMVDDHRNSLRAAEASSKNKKRLGLPEDLVEKALRFKVYYEKYEALYRDIAGRSNAPKDRVAELLKMHTRLQEMKSDIHNEAMMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT82</accession>
    <name>A0ABR3ZT82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019021">
        <property type="entry name" value="Mms22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09462">
        <property type="entry name" value="Mus7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1435"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1443"/>
            <end position="1452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1611" mass="180510" checksum="C5F3401DC6F31442" modified="2025-10-08" version="1">MPTPAFIRVAARTARRRTTLGKTSPSRKVINLGSRGDNVDAMSVLRDWKAGKIRPKIPNPPRRPRQSGQQPALQEMSLNLAPHSAPRPLAAHKAATAGKSQPGAFVNRIPQTKLSAPPIPPNLRINMATRTDAMMRPAQLETAARSKPGAAGFISKKKELDDMYRRRRRDAVPLPNVRLEQFVDDQASAYGAVDDYGSAADQPFEPLNFDFEDDIQPAASHHAHGYNATQKTPENNRKRSRFRKRYNPRQVDTSAPRFAHALDPIPLDIAPVMVDLVANTVDLDADKLHGLGPFGSQYPQHFDVFPLDGDVFFHQSTLIGSGRLRLAFGTASLNSSQPARLPDPTTSFQLDERSLRWSTWDEVSSSEYGILMDWLADSLCSLDSPTAPAAPKVHTMVNFLLDFIQTTMATAASEPTARKAFVVRNLEVIKGFIARFEALGQATTSTAGNGLLSALSGIMVIVTWLLQICRDTPECVSYSFQIEDMLKAAAKLSVKVLLKRGLSDMRTSYIDFQRGLFRERGIRRNMQALNSWVVLMQVLEHARIPRAGFWDVTYSVMLADKTAISSCTNAGQFEKLWEDMFTLLPLGEFDSSGAVRPGIRQTLPLDGWELPKKALDRVFQLYKGNLHQSPSFNAYCRAIVGRCHYLVQEWGWRRCKTIVGTIFDFYGSQGFAHLRNEEAHRSPHFLEELAGTPSLAIEPDDKCFHIFIKMLGLVILQLKRLGQSKEMSNLVSRILPNHDRQLLKEMDVHERDLAALRNHHDLLCTLYWAASPDIRPPIHQIEKLVVPANSHKEACLINIRAWNQLARFVISADEGYVVYKGFNSWMKNIFQQMLDQYLSAETDMHRQFQNLSTAMMQGISPDMVKAMAAANRAAAMDVLHACVVSSLDVLRHAKTLGVATYCFNVDQLSAIFTQMDLPGPKTNWSILSTALDVVDHYMDRLEKAMDDQYSSSAEATDPQEADDAVLMLDHRLAKGFFRLNNTLTHMSWDDLPKATADTRVACTERSVTVAARLASRFIHSGVYGLSRFFGSGDYSIFEKLPHAPGLMQRKYLPLFVAAVVRSNVFDFKDLGNSILDLWMLAIVKPQQFLAYENRLAEVLRQHDLPYVRRAHVPANDQTPNYDTNRDFFACAMVSIRKQLRDADGSTRRQQLRGDFARALKLVMQQMKEDLSYAKTEPTEHEKYIVFVRGIVALIRSHGSDICQLDNFFYDQSQEFSPSPEDPQLRTASIITYGLRLGEGEATAAPQLFHYLHNNFNIALANNKLDQECKILERSMENDNVLGFMMERMLPAILRATSEAEEAWPMLDVYYSAMERFVTRSPVPKDIGDDNVTGGVVGLLEDIVAWLQWAASTLAADAVSTGASGDTQPTTFCVRVHTMAQLAALANLLQPYLMTCSCLPISATIQARLDGAIAGFYWFIESVLVDLAPPRIDKRRRYVPPPDDNNDFSDADDVINPPEPKTLFSTFLVDQDDFVSSNFRNSNTFETYSRRISNTTATRRYTGGNTGPGDRAQVDLFSKKVVQHVRDNWIVDKWSISVRKAGARPGMMAAAATTAAGGPGVPFGPWSMGELLAELQRQLDLWKLRPAGTYGMKPHSKRLYPGRLRETKKVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTK7</accession>
    <name>A0ABR3ZTK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein fmp52, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FMP52</name>
        <name evidence="5" type="ORF">Sste5346_000631</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMP52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF7">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="12"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="246" mass="25903" checksum="8A54FC598E571E78" modified="2025-10-08" version="1">MAAAPITSAVFGATGLVGAHLVTSLLSLDAFGTVHTITRRAPKQASDAALSKKLDAVVEKDTEQWVPKFKEVVATTASTSTPTVFSALGTTRQAAGGIANQWKIDHDLNVEVARAAKAAGVKTFVFVSSAGTRSLLARALPYSKMKNGVEDTIKELGFEQAIILKPGLILGDREVEHQGAGVFKALVGATKNVSKAWHDSLGQDADVIAKAAAHAALLASQGKAPSAYWEVEVADIVRLGRDEWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTL6</accession>
    <name>A0ABR3ZTL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carboxypeptidase C</fullName>
            <ecNumber evidence="2">3.4.16.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_000048</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.5" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046817272" description="carboxypeptidase C" evidence="8">
        <location>
            <begin position="16"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="521" mass="56850" checksum="FE6F799998653FB1" modified="2025-10-08" version="1">MHLTTALALAGAASASVLPPILDSIDSRLDAQIRLSPSAPPLKETARSRTSATVASSPRPFSIREQGDDVCRAGTRQYSGQVNVTDDKSLFFWFFESRNNAADDPVILWLNGGPGGSSMYGLFEEIGACLLNEFNNDTYVNEHSWANYANLLFLDQPAGVGFSSDQRNGSIGPNTLEEAAADFAVFLDTFLHDVFPQLAGRPLHIAGESFGGSYVPYFTSRLLASANVPDLEVESIILVDATVDGLGAGVLGYYDHLCAVDEQGHRKTLRGWLGGLNETACAAMERDMPRCEQLNVLCLATYDLDVCAMAAEWCMFNLGIWLYSDVVSGGRNPYDDRRPCNNPPMCDDFSEHGYSEYLNRADIQAALGIAANTTFEGVNLALNTHWLASKNMFRPTTREVTYLLDQTPARVLVVNGNNDIIVNTEGQKRVYDNLPWSKQALYRISSWVDWVWPDTSSSNKDNGIVDIMTVGGQIKTAGKLSFATVAEAGHASPADQKPAVSFLVHCWITNGKSDPRCPQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTR0</accession>
    <name>A0ABR3ZTR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDC14</name>
        <name evidence="10" type="ORF">Sste5346_000735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14499">
        <property type="entry name" value="CDC14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044506">
        <property type="entry name" value="CDC14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="218"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="9">
        <location>
            <begin position="302"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="541"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="607"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="570"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="658"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="680" mass="74973" checksum="26DA6DAA6A7D243B" modified="2025-10-08" version="1">MGQVIEYLPDRLYLGSYLSQPDADTLFPYGASAPKSPSKRSRALASEPAATKPSPEPYYFTVDDSLLYNAFHHDFGPLHVGHLYRFALHFHEILAATESQQRPVVFWSRADPRSRANAACLLACYMVLIQSWPPHLALAPLAQVDPPLMPFRDAGYSQADYGITVQDVVYGVWKAKEEGCCLLDNFDLAEYEQFERVEHGDFNWVTPHFLAFASPQHTPVARITEDSELYASLPRTLDAVDAHPTLPQPFKNVLRHFSERNIGLVVRLNSQLYSPSYFEALGIQHLDMIFDDGTCPPMSTVRKFIRLAHEMITVRKKSIAVHCKAGLGRTGCLIGAYLIYRYGFTANEIISFMRFMRPGMVVGPQQHWLHLNQGVFREWWVEERLERRLRREFAATQAAASANANNLPSTPIRAMQKASLGRSQSTSTPPNRSASGRTPLSEVDKERNNVAQEDYLPAPTPGQPRKSARADRHHPYSRSKTGSYSTATSTVEEEDAAAATLGDEAELFAILQENGGDDQSSRGSRGTDSEEEIHLRMRMHRKANAAASSSPDGASRHQKSRSTSHNSRNTVTATTTTTTTTTTAIHENDASFDAENIGSSISRVKSIKEVQGREHRSTSASGVLAKVRGSDRSGSHASAKRMPGAQPTGIRKTSNRVASGGNAATATAMASAARKISSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTY9</accession>
    <name>A0ABR3ZTY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="19037" checksum="B6C15990ED09808D" modified="2025-10-08" version="1">MTYSKYYGAPSNPYFPNKKVAGTDVGHTLQSSYEKKDNNDGGSGNSNNRHNNKFNGNTKYNRSNTTGPYNRPSKNAFFSGEGPSYRGDGKDSRFDKHRKPLQERKPFSSTMPFTINFGAAGKEESAEFKAMFAEDNPTVSGEGLYMDFLFRSWSQMLDRLLSKFTDPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUA2</accession>
    <name>A0ABR3ZUA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.70">
        <property type="entry name" value="Get5 dimerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049256">
        <property type="entry name" value="Get5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024737">
        <property type="entry name" value="Get5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047154">
        <property type="entry name" value="UBL4A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46555">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46555:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17183">
        <property type="entry name" value="Get5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12754">
        <property type="entry name" value="Get5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="62"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="222" mass="23871" checksum="9768543EF0BD4D58" modified="2025-10-08" version="1">MTEVQFAKVFLGNLDGRPIKLQADYIEDPKSYPSRPPYTLPRMPKPMKKPAAALAPGQVPAVTVSIKSLHRTQPLDVTLSSPEYTFALATTSLLDVKTALSEKSHVPADKLRLLYNKKPVTDSKVLKDLVTGDETEVKLGVMVSGGAETVAAAEAAAAQSKSAAATPAATTPAATAEPTAVVAESEAFWNDLRGFLVKRTGSKTQADELFSLFLRSWEERMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUY4</accession>
    <name>A0ABR3ZUY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable cytosolic iron-sulfur protein assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">CIA1</name>
        <name evidence="6" type="ORF">Sste5346_000304</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat CIA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03037">
        <property type="entry name" value="ciao1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028608">
        <property type="entry name" value="CIAO1/Cia1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920">
        <property type="entry name" value="WD40 PROTEIN CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="294"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="380"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="476"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="590" mass="64187" checksum="F72F09FBED2A6715" modified="2025-10-08" version="1">MDPASGSGPAVAEAVTSSTTTTAASTSDPVQTLQQQSLRLQSVKEIRTLPSFQPDLYQRGWYSIPHPTLPLLATAHNKSVTIFSLATFSAHSTLTGGHSRSIRSATWKPSLPPNKLCLVTGSFDSTAGLWRYEQNGESGGAASGGGLETEVTAVNRRAATAAGDSDNDNDGGDNDEEDDGWEFTLVLEGQEHEIKSVAFSPSGQYLATCSRDKSVWIWEDVGGDEDDDEWETVAVLNEHEGDVKCVAWCPDVPGRRSGSGKHYSLDVLASTSYDNTIRIWREDGDGEWVCVAVLEGHAGTVWGVQWEADPTRKRFPRLLTWSADQTLRIWELEEENEDEEASGDAAAQGANPLFRSNLGGVPNTMRRSLHEPWTCTAVLPKAHTRDIYSASWSGSNGLIASTGSDGTVVVYAELDGPAPPDNEATAEDEAAAMLDGDVHMTNGTDAAPAASNGRSRSPGRINSHNHNHAHGHSHAHGHDHSHDHGHDHSHDHDHDHSHDHVHDHSHDHDHSHDHEEETQPHTHSHVAHHSTAPTKHWRVVSTVASAHGPYEINNITWCRRFDSGTERRGVEEMLVTTGDDGVVRPWEIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGL7</accession>
    <name>A0ABR3YGL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000130">
        <property type="protein sequence ID" value="KAL1887294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR ASQA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="352" mass="39004" checksum="5EAC36F52990F864" modified="2025-10-08" version="1" fragment="single">MCHGKSALTWLTYGTHVRAIVSTAANIHRAVFGRYDDLLAAHKPPLSTPYRHPAVLEQCALILSNLVGPLHELGDQVPEELRLPRLPGGNSEPFSFDSSSVRLDENIPVWLQNQRLYLEMTYHSMAINLYRPFISFYRRGAGSGALYRYLPTTDRHAARAARHAITFVRIVHKVVHNTTLLAPTWNEYFQWLWNAVVTLVGFLFAHPLHPTTTAAREAAECAVSVCDIYAASRFTVAADAATILRCFLKRVDELFARVVAGVPAETGLSSDSTTPTLPSVSGETLLLEAHSEGSIDVVSSDMAIDDPTLSWLDPQQPGNPESLNLFMDWALAVDSFNNFDQLLGPSMEWDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGM5</accession>
    <name>A0ABR3YGM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferrioxamine B transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIT1_3</name>
        <name evidence="10" type="ORF">Sste5346_010182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="607" mass="66121" checksum="35A8508E55C697EE" modified="2025-10-08" version="1">MAEKQVNTVDPVAPASAPEIAYDNKVNNNDVKNADGLNTNTNEKPLNASNSSLNDQSAGVNRIEALAAVLTRTDRFFLFFGVFLVAYAYGLDGTTRYTYQTYATASYAEHSLLASINVLRSVIAAAAQPTAAKIADIFGRVELVLVSILFYVVGTIVQASSNGVSAFAGGAVLYQIGYTMVILLIEVIIADLTSTRARLLFSYIPALPFIINTWVSGNITADVMAATTWRWGIGMWCIIYPVCCLPLIITMMLVARRAKKMGLLSPYTQSLKNQRGSRSFLVDLFWRLDVIGIILMIAVFALILVPLTLAGGVSSTWHEAHIIAPLVVGFVCIPFFIVWEMKAPHPLVPFRLMKDRGVWAPLGIALFLNFAWYMQGDFLYTVLYVAFDFSITSATRITSLYSFCSVITGFLLGFVVFRVKRLKYFILFGTMLFLVAFGLLIKFRGAATASNRSGVIGAEVLLGIAGGMFPYPAQASIQSSLKHENLAVITGVYLATYNIGSAFGNTVSGAVWSQVLPATLEKNLNPINSTLAPLVYGNPLAYADLYPVGTIERDAIIDSYKHVQRMLTITGIGLCVPLIVFALLLRNPKLNDEQTLAKSSDSDSVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGS1</accession>
    <name>A0ABR3YGS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Sste5346_010139</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145802" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="17"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1887528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="230" mass="24370" checksum="F94B6C8276DBF976" modified="2025-10-08" version="1">MKLLPSLLLMAATARAHYRFSKLIVDGVAETKEWTSIRETKNYQDDHGVTDVTSTDIRCFQMKTGTGYATVAAGGNLGFIADQTVSHPGPVQFYMARVPDGKDLNTWEAAGNVWFKAASIGAEPGTTGKALVWPTYHARSVNFTVPTSVPSGDYLVRVESIALHQAQSAGGAQFYLACAQVKVTGGGTGTPGPLVAFPGAYRSGEPGLLFANYPVPTSYTPPGPAVWPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGW4</accession>
    <name>A0ABR3YGW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAS1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ras1</name>
        <name evidence="3" type="ORF">Sste5346_010127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000115">
        <property type="protein sequence ID" value="KAL1887574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04138">
        <property type="entry name" value="H_N_K_Ras_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="213" mass="24041" checksum="C829148554EE2975" modified="2025-10-08" version="1">MASKFLREYKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDDEVALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSITSRQSFEEITTFQQQILRVKDKDYFPMVVVGNKCDLESEREVTRQEGEALARSFGCKFIETSAKSRINVDKAFYDIVREIRRYNREMQGYSTGSGTSNVGGPSNKIEVSDNDTEAGCCSKCILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH94</accession>
    <name>A0ABR3YH94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_010349</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000134">
        <property type="protein sequence ID" value="KAL1887232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="53"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="60525" checksum="3CF418A017313914" modified="2025-10-08" version="1">METTKNEAREDDVQISAEARFAAVSAEAQAATAKEHSMSLWRGIKTYPHAIGWSILFSTAIIMEGYDVVLMGSFFAYPAFENRYGDLQPDGSRVLSAAWQAGLTNGMNCGQILGLMATGIVAERFGYRKTMLGALTSVIGFIFILFFAPNKPALIAGEILMGIPLGVFQTVTVTYASEVCPVVLRAYLTTYVNLCWVIGQIVGSAVLRALLSRTDEWAYRIPFAVQWVWPVPLIIAISLAPESPWWLVRKGRIDEATASLRRLANGPEDDLTETVSMMVHTTTLEAQLSEGTSYWSCFSSSNIRRTEISCLTWAVQNLCGAGLMGYSTYFYENAGLPTAKSFDMSLAQYGIGFFGTLFSWVLMSHLGRRTLYVGGLFTLCGLLMIVGFISLAPGASTIITNADGSTQSSNIATAWATGSMLLVYTFVYDSTVGPVCYSLVSEIPATRVRNKTVVLARNLYNVFSIVNGIVIPYMLNPTAWHWEGKAGFFWGGLCFLSATWAFFRLPEPRGRTFSELDALFEKGVPARKFASEYVDVFGQESEKSAGIEHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH99</accession>
    <name>A0ABR3YH99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GDH2</name>
        <name evidence="6" type="ORF">Sste5346_010046</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="719"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1084" mass="121843" checksum="5C4F0FCC8ECCA9E7" modified="2025-10-08" version="1">MSSNLKLLTLNTADLPLKFPDYVDPFTSDCEDMSSENSTPPPANKLVGKVREEASRHPSPQPSHISSSLSRAAGNGHRILRSATVGYVAPEFKGRSQQMKEVRDMISSSGWIPESLVDKQITWFYNELGIDDVYFQLEQVDVIANHIMSLYAARVAANSREDKREEIRLDMEAYDHAIYIDTSEPGKSAIGGPRYETRLESKYLDGSDLSKRFRVETFRSPGVLGDASTPRSSLRCYFVYQCQFVDPAADPTESRLEIISDRMFLAKATKNTKQIYQEIIELAVSRTGPVIEVFDIEDSQEKRLVVAFRSRTARGMFSALSDLYHYYGVTSSRKYVEQFSNGITVMSIYLRPATNLDRESPPLEQSIHQITKEISLLYCVPYNKLHNLFASGELSLQEAIYGHCVWVFVQHFLNRLGSEYASLSDALDEKNNAHMLLLSKLKRRLRTETFTPDYILEIVSSYPNLVRALYASFANVHLAVGPGFERHAIAPTPTVEVLSDEGLRAKITKEVSNEHEEMVMTAFRVFNNAVLKTNYFTPTKVALSFRLDPSFLPEFEYPRRLYGMFLVISSESRGFHLRFRDIARGGIRIVKSRSKEAYGINARNLFDENYGLASTQQRKNKDIPEGGSKGVILLDPKQQDKAREAFEKYIDSILDLLLPAETPGIKNPIVDLYGKEEILFMGPDENTADLVDWATKHAFERGAPFWKSFFTGKSPTLGGIPHDEYGMTTLSVREYVKGIYRKLELDPSRVQKMQTGGPDGDLGSNEILLSNEKYTSVIDGSGVLVDPNGIDKEELVRLAKNRVMVSQFDLAKLSKDGYRVLCDDTNITLPTGEVVANGTAFRNTYHLRDTGMTDMFVPCGGRPESIDLVSVNKIIKDGKSIIPYIVEGANLFITQDAKSRLESAGCILIKDASANKGGVTSSSLEVLASLSFDDDGFRQHMCHNDKGVAPGFYKAYVKEVQNKIQENARLEFEAIWREHEETGVSRSVLSDKLSVAITTLDEELQKSDLWEDEKIRRHVLGDALPKLLLGQIGLDTIIQRVPDAYLRAIFGSFLASRFVYEFGSSPSQFAFFDFMSKRVAQIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHD5</accession>
    <name>A0ABR3YHD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18657">
        <property type="entry name" value="CSD_Swi6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="103"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="275" mass="30953" checksum="73B876865A365BF5" modified="2025-10-08" version="1">MPPALSDDEMSDASGVGAVTTPPPSKRGRKVGSYVDTADNEDEDSNDSSDNAKKRDNGRAKSGTRTNGASSSANKKKEEEVKDQDNGNDDDDDDDDEEEGDEYEVQKIIDHILDENEKPRFRVVWKGYDNPSDHTWEPEDNLKENASEILSEYISKIGGRPKLFEKPTKGKKRGRQPASVSPTTATKRSRKSEDHPVDRESPAEVQKVFKPPAGSWEEEVVDVEMFRGDDGELRVFLTWRNGSKSQHAAQQAYLRCPQRILRFYESRISFKSPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHH0</accession>
    <name>A0ABR3YHH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin fusion degradation protein 4</fullName>
            <ecNumber evidence="5">2.3.2.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UFD4_2</name>
        <name evidence="5" type="ORF">Sste5346_010024</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="4">
        <location>
            <begin position="85"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="183" mass="19660" checksum="727A6D271F52ABB0" modified="2025-10-08" version="1">MGLGTLRDGSSGVRPSLGAVKVVDPALARSLLLIKRFADAKKAIDESAECPAGKRDAAIEAITINGAHIEDLGLDFTLPGYPDIELIPQGCHVGVTMSNVETYVDKVVSMTLEGGVRLQVDAFRRALMDSVKADHGFNMDSRSVKNLLQVMSEMSPSERRDFLQFATGSPRLPIGGTFSHIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI15</accession>
    <name>A0ABR3YI15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-galactosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.20">
        <property type="entry name" value="putative beta-Galactosidase from caulobacter crescentus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040719">
        <property type="entry name" value="DUF5597"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18120">
        <property type="entry name" value="DUF5597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 42 N-terminal" evidence="3">
        <location>
            <begin position="49"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5597" evidence="4">
        <location>
            <begin position="398"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="62923" checksum="341477FB1B98A801" modified="2025-10-08" version="1">MEGPSTKTSQLRKVGASWQLLVDGKPYLILGAELQNSSMSSAAYMDTVWEEIVKIGVNTVLGVVAWEDIEPKEGKFDFGELDAVIFAARKHKLRLILTWFGSFKNGMSCYVPTWVKTDALRFPRMRCGDPDGSTDVANVISIFNEECVRADAKAFTMLMEHLKQIDGQRTVILVQVENEVGLLGDSRDHSKMADTLFHAPVPAELSEFLVGDWDSMHADLKCNFPSLTSNITTQLASTGRLGSWEAVFGASVYTDEIFMSYYYALYVEHVAAAGKKVYDIPLFTNAWLPKPGTSAGSNIAAGGNLPGDYPSGGPVSTVLDIWQKFAPTLDFFSPDIYTSDYLQICNTYTHRGQALFIPEQRRDEYGARRAWAAIGTYRALGVSPFGIDTLKAKDCAYTKHYHLLASVSQIILKAYMKPESIFGFFFDELNIEDTGGAAPSTIMKSFQDYALTISRAFVPGSSGPGAGIIIELENDRFLLIGCGFKVEYKSTRPGSVHTGILRFLEKSVADPATGELRTERKLNGDESRSGLWANMPNEVLDYAGTVVPICIPARTMIAEVTVYSLSKDGVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI83</accession>
    <name>A0ABR3YI83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009868</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08278">
        <property type="entry name" value="benzyl_alcohol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF20">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="18"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="373" mass="39514" checksum="BDE2E8DABDE7B90D" modified="2025-10-08" version="1">MDGIKARRTKAYVVDHVGGPFELTEVFLDKLRDDEVLVELLYTGLWQDIVVKDGGMPVGGFPAVLGHEGLGIVREVGPAVADKSLQLGDTVILSFHSCRRCSWCQQGQYGGCPHMTETNFINTARQGVANESPISLADGRRVHGQFFGQSSLSKLTVATEKSVVKIDAQPADLAVLAPLACGYLTGASTVLSVLQPKKTDKVAVLGMGAVGLAAVMAAKARGVVDILAVDIVDEKLRIAAEVGASHTLNTSDLNTGLNEGIRRIFATGVDKIVDATGVVPVINDAVKALGHGGTLALVGVPPPNKTLQIDALDMLLSCKKIMGVIEGLSSPQQAIPELTKLYYEGKFPIDKVATVYPAEDMSRAIDDFKNGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIL4</accession>
    <name>A0ABR3YIL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MmgE/PrpD family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000112">
        <property type="protein sequence ID" value="KAL1887668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF8">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="3">
        <location>
            <begin position="287"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="49504" checksum="834F4C59A65FACB6" modified="2025-10-08" version="1">MATQRLASWAKSLEYSDLPDEVVRAAVRSFYNWAGCAIGGSTHPATTIAQYQTLHPLFGPPTASLLGHKEPLKADPQHAALINGIASHVHDYDDTHLDTIIHPTGPVASALLAVAEWKKGVTGKDLIVALVVGIEAECKVGLAVWPEHYDVGWHITSSTGSIGAAVAVSKILNLSTPETAHAIGLAATQVVGLREMFGSHTKSFHPGRAAQSGLLAAIMAQGGYTSSEQALEAKRGWANVVSSPKTDVQQRLANFIGIPSGSQASTLGLASTEAGRWEVLRNSFKPFPCGIVIHPIIDACAQLNNEMFQKRLELADIKAITAKVHPLVLELTGKRTPKDGLEAKFSVFHSGACGLIFGKVTPSEYKDSVVLSDEVITVRDLIQAEIDPALTADQAIVTLALTDGQTLEKHVKHAVGSIDVPMDDAMLQKKFLGQVSKVLSNAEAASKALWELESMDDVSAIASFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIV7</accession>
    <name>A0ABR3YIV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_009776</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000100">
        <property type="protein sequence ID" value="KAL1888089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="388"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1087" mass="118672" checksum="D93D7E99E76F9077" modified="2025-10-08" version="1">MDGQKLASLLQESQIPDTTRIKAITAELQKNYYSRPESLLALIEIVCTHSDVNVRQQAAVQAARLVPRHWKSPTAEQKVAVRKHLLDATLQEQNAKCRHSDAHLVAAIATFDFDDGEWPELLPALFTLATSNEPAQREIGSYIIYSTLEANPIIYKDHVKKLLGLFAQLIKDPASAEVQINTVLSIGSLPVLIEADEDEDEEAVAAVRDLVPPIGIVLKNAVDNGDDDKIQAVFEVLQQFLVFSPAFVGVHLKALVQFMIELSANKEADDDVRVQAMSYLTQTVHYRRLKIQAMKDMAAHLVVKSMEILTEIGDDESIDEETPGHLALSLLDALASSLPPRQVLVPLLDEFPKYASSADPALRKAGILALGNCAEGAPDFVNTQLKTILPVVIQLLNDPDETVRHASLVGLTGLAEEMPESVAVEHEAIMTALVKNLQASMVATSDEAAQKKNSQVIRAVCTAFDSISNGLKGETMKQYALQMIGPIGQLFEHPDLRVKIAAASALGAIAEPLEQDFAPYFEKSMHALGSYVTIKGEELELQLRSAVLDSIGRIAIAVGPKLFQPYVVDLMKASEEGLTLDDDRLKESSFIFWASLAKVYGREFKPFLPGVLKTLLEALDGDNDDTVINLTDEEKAIIAAGGVSGNVLVGGKKVKIEDLDAEDLDDSDLMGDSDDDDDDDWAGIDSEAEEKEVAIEVLGDIISNACGEEEMQEFLEKAVSAAVDLTEHHYGGVRKAAVGMLWRSYARVWQLTEESTGTKWQPGFPPKAAPTPLLAKLAEMVVRPTLDLWTDEAERDVVTDINRNVAATLETCGPAILAQENAVQEIVSVLGQIITRSHTCQQDVGDEEDAQNAEESSEYDWLVVETALDVVMALATAIGPAFGELWKIFEKPITKIASSNESYERSSAIGTIASCAGAMGATVTPYTTPLLKLIVHRLSDEDLETKSNAAFAAGQLVTSSTDSKTYLAAYPTILEKLERLLSMDDTGHRMYDNAAGALCRLITAHPDHVSIPDYLPAVVARLPLKEDFEENKNIYTCLYGLYEHNEPTVQQLTPQLVPVFQQVLGAPEEQLDDDTRALVQQIVSKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIX0</accession>
    <name>A0ABR3YIX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purple acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000108">
        <property type="protein sequence ID" value="KAL1887797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF10">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364974" description="Purple acid phosphatase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="171"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="7">
        <location>
            <begin position="409"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="617"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="617"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="629"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="660"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="749" mass="76890" checksum="E7588184F929201B" modified="2025-10-08" version="1">MRFFAFLALAGQAVASVVIANSSVTSQVRVAYHGDDGMVVSWNTFKQLSNPTVLYGLSADSMTESASSDVSVTYPTSLTYNNHVWIDGLLPDTTYYYQPQDLLANETVYGPYTFKTARPAGDHTPYSIAFVCDLGTMGSGTLGLSDIPNSKLDDNEILKPGEKTTIDSLVALMDSYDFLVHPGDLAYSDYWLKEELAGYINATIEEGPAIYETILNEFYDEMESISAFRPYMIGVGNHEANCDNGGSGSYDSSICVEGQTNFTGVRNHFRMPSDISGGVGPFWYSFDYGMVHYVYFNTETDLGNGLLNDEQAPLSAGPFGSYPNEQVDWLEADLATVDRCATPWVVALGHRPWFTSGDNCPNCSVAFSQMFENHGVDLVLQGHFHVYERNVPVFTNGTIDPAGYDNPAAPWYLINGIAGHWGGMDVFTYPVEDFQVFGLSDANATYGWSRLHFFNSTHLQHEFVASNNNSVLDTTILYKEHVCLSQSSSSSAVASSTSASASASGIVSASASSVTASASGSASKSASGSASGTPSSIADCETTSVSGSTGVSATGSASVSASAVGSATSSYTTSTILSTTTYTITSCAPTVTNCPVGHVTTEVVTLLTTWCPEATETGSGAGSGAQSTPKVGTTSVVKTTQPGGLPSSVPTGGYTNSTGSGSGSSSGSGSGSGSGSSGSGSSSGSGSSSGSGSGSGSGSGSGSSSGSGSGSGNSTTGGGSTVVTAGSSNIVASAASVLLAVMVGAVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ06</accession>
    <name>A0ABR3YJ06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0357 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018559">
        <property type="entry name" value="DUF2015"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023:SF1">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09435">
        <property type="entry name" value="DUF2015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="140" mass="15340" checksum="A4AE567409C1A5E3" modified="2025-10-08" version="1">MALFLYGLALLVIVAGSLLYWTRQRWIAPLVATVQSATDSISDRLSSIRSPFSYTRLPSTFAGDAEAGLSSSTFDLAGNVEGGDSRAGLDDASKAAILKIMKKRRLPFDEARRVYMEQRFKDNGIGADGRPRDPKFVSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ89</accession>
    <name>A0ABR3YJ89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Plasma membrane low glucose sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SNF3_2</name>
        <name evidence="11" type="ORF">Sste5346_009958</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF15">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="70"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="562" mass="61886" checksum="E3B1AD466FCF9DFD" modified="2025-10-08" version="1">MADSEKAMPTTTAAATDGRESPATDAGVKAKDQWVEDHSSRAHLAAQFTAWERGLTTWQAARIYWRTVLWVIYAELAIFGYGIDGVIAGYLTGIPKFTETYGTPYSEGTVTYIISATWLSIWSGVTQITAIIGALAAGYLADLIGRKYTNLIFCLISIAAVGAQYASTRDGSMPILTAGKAINGFSIGAWIVIAPLYASEVSPLPLRGIMTAATNFIMFCGLLLFNGIMYVLAPMDTDLAYKVPLALQWIMPVFLASTIVLFPESPVWLIRFGKKERGLKAMKKLYGENSGVDLDGLVAQIEEDIEHEKRESHQTTDNRGYFEVFKKEHRKRTLIAVMAFTFVQASGNIFVLGYQSYFYQLIGYSARKSFLITVLVNVIMFIATISSWWGITVLGRRTLYVWGELITAICLFAIGGASVAGTVDAYKAVVGFIFVWAFAYQFTVGTVGFPLLLEVPALRMRARTQAVANIAMSVTQWVIGFTFPYLFNPDAANLSGKVGFIYAGLTVLGFLFSFWFLPETKNRSVAELDALFASGVAPRNFSSYVVDFDEENDNAAIVRKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJD2</accession>
    <name>A0ABR3YJD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="32"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="336" mass="37881" checksum="55F6EEF913F5587A" modified="2025-10-08" version="1">MDSFQKKTLVTARSLKYTYHVSRSGEVTDNCPALLFLHGFPDSAHLWTDVIANLGSVPNKIIIPDCLGYASTDKPEDTALYTYDGQAADLVDILGNENILDGAQTVLIGHDWGSALAQRTYLYHRELFRGIVLVNTGYIVPSADKFDLDAVNTLTEKLLGYPQFAYWELFTAPDAAEVINTRLDRMWQALHGDHDQWMKKLFCEKDGMRNFILGDENVPLRPYARGPKFRDHFMEQFSPEKGGFFGAFQMYKSTANNVQAEAFEKLPEVNLKIEVPILYFICRQDAVCLPELMMEPAKGMGLVPNLKEVVLDCAHWSPMEKPVEIATEIKAFLGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJJ2</accession>
    <name>A0ABR3YJJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11616">
        <property type="entry name" value="SAF_DH_OX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048423">
        <property type="entry name" value="DRL_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37850:SF3">
        <property type="entry name" value="BLR7815 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37850">
        <property type="entry name" value="STRU PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21135">
        <property type="entry name" value="DRL_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="1">
        <location>
            <begin position="365"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="468" mass="50264" checksum="0BF697A533425F19" modified="2025-10-08" version="1">MTSLSTKLAALEEAGKPIQVGIIGAGKFGSMFISQAHRTTGLRLAGIADLSKDRALSSLQRTGFPAEKYDGTATLTIEEGIKAGKTAITTDSAELIATPGIDVILEVTGNPAAGIRHALLCCEHKKHIVMINVEADVLAGPLLARKAKEAGIIYSMAYGDQPALIAEMVDWARTAGFEVVCAGKGTKHLPEYHYSTPATVWDYYGFTKEQLATGDFNPQMFNSFLDGTKSALEMAAVANGCDLMPPTKGLQFPPSSVWDLPEVLKPQEAGGQSEHSGTVEVVSCMEKDGRWTFNHLRWGVYVVIKAPGEYQRECFKQYGLKTDESGWYAAQYKPYHLIGLELGVSVATIMTRGEPTGQTKTWAGDVVATAKRDLKAGEKLDGEGGFMVYGKLMPAAASIAIEGLPIGLAHGIVLKRDVKKDQGLSWADVEYSDKAQAVAVRKEMEALFRKEFAAKSNGVKANGANGTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJQ0</accession>
    <name>A0ABR3YJQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome production factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPF1</name>
        <name evidence="3" type="ORF">Sste5346_009489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="210"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="438" mass="49876" checksum="F3336D78CA741343" modified="2025-10-08" version="1">MGSRNKIVRQSSWLQSKAAKGKKSIADRRERRREEEKYPELKAERLAKNKPKTLEDKREYPVSEDYYSRRKRRRVAEEKPAEEEAEAEKAEDVDDAQDEDDKMGVEEEDAKVGDDEVDSDIASLLASDDEEEEENTAGLSKADKKTRREQAQAAAEAKRKEQDEKEAAEEAAARAAHEDAMAAKYSALLPDEDSSATADESGSTATPVQPKILITTSRHATIHKYAQTLTDVFPNSTYIPRSGHRYVSHEYSVREIASYAHNRGYTALLIVNEDQKKPSGLDITLLPNGPMLHFSIQTWVDAKRLPNHARSTGHVPEMIMNNFDTPLGKLVGGVLDRLFPKNPELIGRTVLTLHNQRDYVFVRRHRYMMREKRATERSVTEKDGKAMTGVEDVRVALQEIGPRMTLKLRRVDKGIQRMSGQAFEWKGRMEKKRTVWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJT1</accession>
    <name>A0ABR3YJT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Golgi membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009839</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="206"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="35653" checksum="F703867D16710574" modified="2025-10-08" version="1">MAQYGYGGGNPAYGPSSAQNLQFYPSSYSPGVPGQPTTGHGGAYGYGGSGGVASAYGGAIGSGGVPGVGGPGGVSGRMGEQGGLRTGWLAAFSTEGYDGEPPLLEELGVNFRHIQAKTLAVLNPFQRIDQHLMDDYDLAGPIIFFLLFGTFLLFSGKVHFGYIYGLALLGSISLHVILSLMSPDNQPGSAGGSGLGPSYAQSPAPGYPGDTAAGSSSGVSGNISSASPSKNGPTSKHGRSGSLSQLSSTLTFVRSASVLGYCLLPLVATSLIGIMMPMDTPLGIVLTTAAICWCTYSASGMFCAVGRMRGMRALVAYPLALFYVGFGIMGVFSSRGSGSMAKVIASRTGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJY4</accession>
    <name>A0ABR3YJY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009758</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="415" mass="45789" checksum="BDED6C0C78504C3F" modified="2025-10-08" version="1">MTATSAKRPCMGLTEGRLLTWITFACSMDMLMFGYDQAVFSGVIVTDNFLELHDLVGPSRTNVLSTVTAIYDAILTGTAIMSVGAILMSASFSLPQMFVGRIILGLGNGINTSTAPIWQTETAPAHLRGKLVMFEMMMNIVGFSLCNWINFGLSFASGAVAWRLPLALQFVFILSLFATVPWLPESPRWLVYHSRDTEAKEVVACLAAKPLDDPIVLAQCEEIKYGVAYEKEHAVRWRDLLKSTTPDGTKPLRRLLLGAGTQFIQQFEVLTVAVGLSNELARLLTAVNSVTYLILSCISITLVESGGSGGETNRAAEASIVFFFLYFMSFGFGMLGVPWLYPTEINSVVMWTKGAAVATATNWITNFVIVQITPIGIQNLGWKFWIVFTVFNAFFMPVIYFFYPETGNKPYIGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKE8</accession>
    <name>A0ABR3YKE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BTS1</name>
        <name evidence="6" type="ORF">Sste5346_009398</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF44">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="393" mass="43148" checksum="CA1504DFE6F027B6" modified="2025-10-08" version="1">MASLKASAAAAAAASGNPTGLSTSGADKPTPSSPLLDPTKQLPTLPSQSKDNKASDSSSSGPSSVAASVLTATALQPQPPQDPRRYATEDFNFSARRTWTDEKERIVCGPFDYLNGTRGKEFRTQLINAFNGWLEVPTDSLEVITRVVGMLHTASLLVDDVEDSSSLRRGLPVAHNIFGVPQTINSANYIYFVALQELQKLRNPKALVIFAEELCNLHRGQGMDLFWRDTLTCPTEDDYLEMVGHKTGGLFRLGIKLMQAESRSLVDCVPLVNLLGLLFQIQDDYRNLLASEYSQNKGMCEDLTEGKFSFPVIHSIRTNPSNLQLLNILKQKTSDEEVKRYAVAHMESTGSFAYTKEVLQVLTERARNLADALDEGKGRSQAIHAILNRLSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKF9</accession>
    <name>A0ABR3YKF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000086">
        <property type="protein sequence ID" value="KAL1888751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046306823" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="407"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="780" mass="82263" checksum="68E3B1E85CBF7C17" modified="2025-10-08" version="1">MKSVSPSLVLLALLGYFTAAIPATFWMEEVAHQGFAPYAEDGYVVFRNVKDYGAKGDGVTDDSDAINAAISDGNRCGQGCQSSTTTPAVVYFPAGTYVLSTSILPAYMTLLIGDANSPPTLKAASSFTGLGLIDGDPYYNSPDPNWLSTNLFYRQIRNFVIDTTAIDAATLAYGIHWPTAQATSLQNVKFVMPTTAGVAHIGLFIESGSGGFMTDLTFEGGAIGASLGNQQFTMRNLAFDSCVTAINQLWDWGWTYYGLDIKNCVVGLNISSGGSSAQSVGSITVFDSAFTSVNVAVVSAYVPNVSQPTTAGSIILENIVANQVPVIVQTPDGNLLTGGAAVTVAAWGQGHQYIPNGPTSLQGGFNGNERPSSLLASGNPVAAAAGVPGSYYARAKPQYETLRACHFMSARAAGAKGDGVTDDTAALQEVINFATRTGNVVYIDYGLYLVTSTLTIPPGARIVGEAYPVIMAGGDSFFKSDSNPQPLLQVGATSGEQGTVELSDFVLATQGAQAGAILIQWNLDASASSNLGGLWDVHTRVGGFAGSKLQVAQCLKNPQSSTVNTECIGAFMSMHITEAAAAVYAENVWIWTADHDMDDWNNTQISIYAGRGLYVESSAGPVWLVGTAAEHHTLYQYQFAAARDVFMGQVQTETPYFQPNPVATVPFEANATYNDPDFSGCDSNDATCAMAWGIRILNSDTILVYGIGLYSFFSNYAQTCIPGRSCQARIASIEGSSTTVNIYNLNTIGATSMLDKDGTSLASAADNENVYPDTVALFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKY3</accession>
    <name>A0ABR3YKY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP phosphoribosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000082">
        <property type="protein sequence ID" value="KAL1888946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41774">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41774:SF1">
        <property type="entry name" value="NGG1P INTERACTING FACTOR NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="143" mass="15503" checksum="4FA7B76647D061CA" modified="2025-10-08" version="1">MFARRISAPLNRPASFTSRPYLTYYSTMANPTPTKYQLSFVVPPENLEACKAAIFAAGAGSYPGQGNYTECCWTITKGGLGQFRPGNGANPHIGTVGDLEYVEESRVETLCVGKDVARAAVAALKKAHPYEEVAYSVVKLEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLB4</accession>
    <name>A0ABR3YLB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase</fullName>
            <ecNumber evidence="5">1.1.1.101</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AYR1_3</name>
        <name evidence="5" type="ORF">Sste5346_009450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.101" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000140">
        <property type="term" value="F:acylglycerone-phosphate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="284" mass="30224" checksum="FFB09D4C1F3C123F" modified="2025-10-08" version="1">MPSTKKTVLITGCSAGGIGHALAEAFQKQGLTVFATARNVSKMNGLAALPNVNVLDLDVTSKESVASAVAQVTRDTGGRLDYLVNNAGQSGYMPALDEDLDDPESAARRIFEVNFWSMLRMIQAFTPLLMESGGTVVNVGSVNALVHPPFCVIYNATKAAVHSLGETLRMELQPLGVGILTIITGTIRTQIQANVPVRPLPDNSLYKPVQPYLDSMYAGTAHPNKMDAPVYAQNVVSDVLGGAKGHVYRGTNASNACYASMLLPESVRDKILTGPTHLNEVGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLV6</accession>
    <name>A0ABR3YLV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dimethylaniline monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53907" checksum="19F7CC75EAD471CC" modified="2025-10-08" version="1">MPPRYRRVAVIGAGPSGLASVHALASEKIFDTIRVFERRDQVGGLWHYDPKPDTFPTTTGVPPDQTHKPPVPTSDLPAFAPSSPPDLRARSALYYDLDSNVGAESMAFTHTPFPVVNSPVSIERFGHNNPSRPYGVINNWIEDLFRPYLSLVTLRTTVEKVEKRGNEWVLTLRRSGQLYRGKPHDYWWTEVFDAVVVASGHYHVPFVPDIQNLIQVSSQLPGQFEHSKSYRKAAKYADKRVLIVGGNVSASDFIQDLHSIVAGKLEVAVRNKNPVLESVYNLPNVCLHTTVKAVERAENNKINVIFSDDSRVDGIDYVLFATGYRLQYPFLHPNPTTPENRVAGFYQHVFHIDDPSLTLVGQVKAGLSFRVYEYQAVAVARYYAGRNGIPLPSPDDQRAWETDRVAKLGPSNAFHAIGPDFEPYFNWLVDFAGRPALGTDGYALPRWDDKWATQGLAILGLKDKYWKRLIAQDQVIKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YML6</accession>
    <name>A0ABR3YML6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000072">
        <property type="protein sequence ID" value="KAL1889584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="600" mass="63530" checksum="C4D821133EAD2BB2" modified="2025-10-08" version="1">MKAPDSIEAVHIQQDDQAKGDLLFEKQTARLDNLAEQIDPNAVGGNLSDMPKGYYRSAAFIGTLSAVCLGNACHYLGFVVPASIISVINADIGPNPAYTWISLVWVLTVAVTYSILGRLSDIMGRRWFFLGGNILGLVGNIVVGTAHSIPVAIGGTTLIGIAGAVQLSFPLILGELVPNKHRAHANMAAYIVGLPFSAFGPVIARAFILQTKLGWRWPYFVSAILSVFAVVLLFFCYHPPTLGMIHSKGGRKSAIHLVDIGGVVLYSSGLFLLLLGLSWGGGQYAWKSGQVIGTIVGGGVIIMAFGFYEAYVPLSYPLVLVRLWTKLPYVATIMTASIGATVYYSMSILWPMQVTALYAAGTSHAGWLSCVAGAGTSLGNLIGCVTCGSLGHQKWQMVVSAVGMTVFMGAMAASDQGTVGLAVAFMVLGAMFVGIMEAVAFVTAQLCLEPEDIGLASGTMGTVRSALSTIATTIYLAILNNKKAAYITKHVDEVASQNGVTDAQLAKILAGFASGNINAAGVSQPVLDMLQDVYKTSYSQSLHVVYLASISFGAIAIIFAFYSPNLETKFNDEVSRRLHGSDLTKKERATTEAVEALGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNB7</accession>
    <name>A0ABR3YNB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cardiolipin synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_008659</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="36478" checksum="F2D947435A362DD5" modified="2025-10-08" version="1">MLRLSTTGCGRGGRRAAATVIPASLTIISSMSPFTLASVWAQTQIQTPSLRSRPMSSLPTVSPLRALSSAPGLLSRAPALGRRSLLHGLLSGTLRRPQHMRLLSDKTSSSSPPAAASPTLPPTTTTRHENIYTVPNFLTVARLIAAPFVGYLIVTDQPGWALSLLTAAAVTDLLDGWIARRWNLHTVVGSVLDPMADKVLMTVLAVSLAAQGGLPMWLAVLVLGRDVGLGIAAIYYRWVSLPPPKTFTRYWDFSLPSAEVRPTTISKYNTFLQLALMGVTTAAPVLAMTDGWAAAVLGGPYDLAPALTVMQYIVAVTTVWSGASYVYSKDAVKILTQKSKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNI0</accession>
    <name>A0ABR3YNI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="27"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="520"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="520"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="564" mass="60679" checksum="7F8BEB33D14148E4" modified="2025-10-08" version="1">MKTSQTAAEKALHDQTNILPRSKLIVALITLSLTLGITMMDQNGISVTLPTIAKDLNAQNTISWAGTSSLIANTTFQMLYGRMSDIFGRKVVFISATLLLLLADLLCGLSQNAPMLYVFRGVAGIAGGGITNLAMIIVSDVVTLEQRGFYQGVLGSFVALGNVAGPFLAGAFIDRASWRAFFYMLAPLCLVVASVSFFLLPSKPRTASLKESASKIDYAGVLSSSIAVIFLLIPISGGGSYFEWTSPMVISMLVIGVCSFVFFIIVEWKLARLPMMPVQIFKNPVLCVLMAQTFLFGCAYQSYLYYLPLFLQNARQFSVLRSASITVAMVVVQSVFSILSGQYLSRRRRYGEVLWFGFGMWTIGSGLMLLLNRETHVATIVGFLMLIGSGVGCSFQPTLVALQANSPKARRAVVISARNFFRCCGGAFGLAASAAVLQAALRANLPAEYRYLADNTYSLPKTQGPDFDAVLDAYMAASRAVFVLQLPLVALCLVGCLFVKDRGLEPQEDRDAVAAAAVVSAPASPVESDPESSSSQIEDAEKGLGGKSSKPSVMEVGEEPSRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNY3</accession>
    <name>A0ABR3YNY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_008499</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="12">
        <location>
            <begin position="215"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="62332" checksum="9E21F29621B46910" modified="2025-10-08" version="1">MLPSRGLVQSSQALRLRQVTSQRACARAFSTAMRSRSGASSMPASGLALGQLSGRRVASLNNSTSSSKTTLLRTPPSSAAAFSLWPFGSGKKFNDAEVAAGAAQPASPAAATSTPPQAAAAPPTEFVPETPVASTAAEVPAYSAPVTDTTASSTSAFESADPAALSNLLDGSALLDMAENQIGYLNALGLDFGWGPTSMCQWLLEHVHVYTGLPWWASVVGVALMFRAAIFLPSLTAAEHSAKLQVLRRNPRYAQAMAEMQANALKGGQGGQAKAMEARLTMKRMQEAMNVSTWKMFVPMINIPFGYGMFRLLRSMSALPVPGLETGGILWFTDLTVPDPYFVLPLASAGIMYLIFRTNMRYMAPEQQQTMKYVQMAITPISVLVTIKMSAGLTFFFLSSSILQMIQTWLWHQPWLRNWKGLPPMHEMLSGGALNNVPGGTSAAQHAARPVAFRIDPNSSWKAPRATSTGVQEAESTAGEDAAAAAKKAEEKILTQPPSAIEAAKKGWGKLMGNAKEKQAASKDKEVLRKAQDYEKRRAMEDETQVYQRREAERQYRAMKKTLDAAKKNGGNGNGKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPE9</accession>
    <name>A0ABR3YPE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED18</name>
        <name evidence="10" type="ORF">Sste5346_008735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019095">
        <property type="entry name" value="Mediator_Med18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13321:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13321">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09637">
        <property type="entry name" value="Med18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="301" mass="32887" checksum="732C8FBB7AC69463" modified="2025-10-08" version="1">MHELFLTAVVPDVDIERAKALLQGLSGMTARGTVHRILYFAGPPQPRGLAVKRAIPQPIQPAQGRLWAELHQQMMRQSFVLQARYPVNRDELGATPAASPGAAAILNGSAPGTLRWTDIPDPTGGSSATEIMRMITQRKKVELADTRNLPAILTDNGYRFKSELIEESFIFYNNGNEYVLVRYHRLPSSAPAAPGTPPTPLSALPTWDSITNVPGGPPSGAPPVDPSRQWLFFVRRHVLDDTSPEKMKKAVEELEAARTQLTGIFAFVPVDRRAHDTRVERPAGGVNNAPAPASQAQKLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQF6</accession>
    <name>A0ABR3YQF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline ceramidase ydc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YDC1_1</name>
        <name evidence="8" type="ORF">Sste5346_008344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF1">
        <property type="entry name" value="ALKALINE PHYTOCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="205" mass="23025" checksum="5B638D1CCEEF3E26" modified="2025-10-08" version="1">MIILLSFCEEDYAVSAYLTEFINSLTNLAYVYYALRYMYGPGSRGLFAPKVDFMAVSLLLLGIGSFLFHASMRQTMQFADELAMLGLTWSLLLGALNIQRTSAYNKLVSVGLAVIFPLFSAFYIWTANILYHSIAFGTILTLIVLRGHYLFHWRVPAFPADKCHTPRTQETPPCGPYTVVFAVMVCNVLNVKSTCMNPKYPDLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQQ4</accession>
    <name>A0ABR3YQQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FMT1</name>
        <name evidence="3" type="ORF">Sste5346_008172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="2">
        <location>
            <begin position="587"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="969" mass="105888" checksum="FFF209F69660D2E8" modified="2025-10-08" version="1">MHQPPAASQPAPFSTPDPSRFRVPKPKRSGRDLTDAGPAKDGRTTTPASAAAARPTPRFAPSWKRQPTQSQADIRTPAQSAVRKFSVAGGMNSGSRSSTAASRRFLSHASGLSSQHRRRHSLGRDPFHGGGEDAIEDGSSPPQAPLQTQQTLEEEEGGILMVVRESPTATRTKQPTAASQPPPRPGIFSTSARRRKQRLGLEDDIEDVLSSGSWPGSDDEDDIVRESGKTVDDHVGEGDNEVPMPDSGPNSIVNTTATAIATPVPQSQLPLARQQMSAARLLSSIQPLKRRRLFVSRGLITSSPSAAGSDQEGGGEADEDQDAHGENHGRPPAFVPRFRQRRIRHAWDGDDIVDDDGSGDGGRNEDIRDIVNYGELLEYSQSSDEDGNTQNKEDDDDEIMDHYHDEEDDEDTILDQTPPRIRRARQRQKDNEEQQRQEQRQRMPTFQRARLFMTARWPIYDEDMGGDHEHTAHNVEDTLSQDLTTTPARQRHYYDALLHQPPPDFFSPQKKRRQKRPRKSRHSNENDLDGLGGLTSPSPAAVAATAAAIYAFEHCASLQALYNVMLQQKIDGPSVSPDMPGRIDSLDVVVRPAKRTGRGLKQVVDSPVKLLATELGLPVHERDTFTGWTPPASTNLLIAVSFGLFVPPRLLRAAKFGGLNVHPSLLPDLHGAAPIEHAVLLGRDRTGVTVQTLHETTFDGGRRLLQGPVDLTQQSEPAEAKAEAKASPIEATSFPSGRTLGIPLDDRVTSDDLHELLAPIGAHLLSEVLRRGLYLPERESQKPEVTYTPPFPPAAAPKLSKGDRQVLWQAEDMKKTTSANIDRQARALGELWTYLQIPPSAKAPQGQTKRVIFDNIDLVACPKWLRVALDGGPTANEWPSGVRTLTFVQDVAGQDGEQKTLTLPFVVDGKSIVFPVGVDANGLDNELSCLRIGSIKVEGHGVHTAKEAVGNFGAKDVSAKDISWDVVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQW8</accession>
    <name>A0ABR3YQW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055560">
        <property type="entry name" value="DUF7136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23584">
        <property type="entry name" value="DUF7136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7136" evidence="2">
        <location>
            <begin position="12"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="334" mass="34163" checksum="159EC9B288D77DFE" modified="2025-10-08" version="1">MSDVTPSNSALVLELDVVFPRAETYAAADVFPIAVTFNDFYGVKPNLSALSWSISGPGDGFPKPTVDDGRFEVYATTTYKASAADQEKSPLAPDSYVSSVLLGYTNVSAWPTQYHLADQLQLSILTDDSSSLGGNDSDWVGIFPTGCGATEFHPAFMKIGSSFGSIVFSIESDAKAVAANDSILQPLAADAPACPAAAGSYLSDLYYKNTTTNGICFEDTVNEDGVANYDTVSCTDRSTVPGVVRTALDAAATSLAKESAEGGGGGRTLITPTSVGASATETGASGTGATAKSGSGSNPTTTSTSTTSAAGNQLPSLRRILTALGVVSLAFVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR08</accession>
    <name>A0ABR3YR08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxylic ester hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008319</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36463" checksum="E10C4EEA367FC159" modified="2025-10-08" version="1">MDRRLTTTDVPAKFLGAVFLTGRIPWRVAPEDPRVSYGLYVPPNKYSTKYTADATEEQKQDTSKDDRLPLVVWVHGTGRDTSALTTDLAAFAEANNCAVLAPFFPANMDGPHDLDAYKMLRSKTLKSDKVLLAILDEVAIIWPGITTEKVYLGGFSGGGQFAHRFLYLYPERLAAVGVGAPGRATLLDDTQAWPNGIQDVDTIFGRTVDRAAIAKVAIQIAVGGNDNKIHGGPEFWVWLREMRAKEAAAKKKAREAKGEVIEDKPADKEAATLPTSFSSRLDSVKELHELWKNDGIESTFTVVPGFAHDNTGVRPHILEFLKSRLEADVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRN9</accession>
    <name>A0ABR3YRN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="3">3.5.99.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NAG1_2</name>
        <name evidence="6" type="ORF">Sste5346_008228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280:SF5">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="45474" checksum="1AD403D14B98F4A0" modified="2025-10-08" version="1">MRLIIRDDEDQASAFVANYIVDRIRTFAPTAEHPFVLGLPTGSTPLNVYARLVEAYKQRRVSFAHVITFNMDEYVGLARDHPESYHTFMWTNFFSHVDIRPENVHLLNGNAPDLELECAQYEQTIVDCGGIDLFLAGIGEDGHIAFNEPGSSLVSRTRVKTLAYDTIRVNSRFFGGDIDAVPRCALTVGVQTVLDAREVVAIVLGPRKALALQKCIEEGINHMWTLSSLQLHPHPMVVCDEDATHELRVKTVKYFKSIEQVARTQGFEQALPTRLRVRPEARQTTSRPSLNTAVPTVSAASGTTTPLVIPSPIKPTPSFVLVHGAPDTPDASPTMASKIGLNSVAANLNATLGGSNNINDVDSDLDLIPDRMGDRIPVPNGAAAAGSGNLGVLPVYRRRLTPTPEQQQQKSLGRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS12</accession>
    <name>A0ABR3YS12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UBX domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ucp10</name>
        <name evidence="5" type="ORF">Sste5346_008008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="4">
        <location>
            <begin position="205"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="431"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="557" mass="61521" checksum="CC955817063961CA" modified="2025-10-08" version="1">MATPGPSAAPNAADPPLTEEQQEAVRQFGTLTAQDEEASIALLRRSGWSVTVAVSKFFDGEDDSVPDLNNLPPPQTGPRPANNQPQRLIDLGDPLSGFEPAGPPVHNVFEQARYAAENGRRIAAERTEVARRIVVQPPAPVVRPSFFMALLLSPFNLGYRLLAGLWSAVQYILGLVPGLGAFRRMASGARAAPRRQLNPRDAASRFKREFEEATGSKSLPFVEMGYTQAYDKAKTEPKYLMMVLLAPEHDDTKSYARDTLLHPDVVEFINNPANNIILWGGSVRDPEAYQVSIEHRVTKFPFMAMICVTPKEGGSTRMGTVKRVVGPVSPAYLVEQLRLTTAKYADDLSAVRAVRVANEATRNIRIEQDNAYERSLAIDRERARQRQEAERQRQEAEQQAREREAEAARQAKLGKQWRAWRATTLAPEPAAGTAAANIVRVAIKLPESRGGERLRRSFAADATVEDLYAFVECNSTEASEENDDNNDEEEGPVREKVTKPAGYTHVYKFRIASMMPREVHEPSESKTLLEAIGKSASLVVEEVEESEDGEDSDAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS15</accession>
    <name>A0ABR3YS15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atg12</name>
        <name evidence="8" type="ORF">Sste5346_008169</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="4 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="203" mass="21041" checksum="3BDB847DD17A3AA0" modified="2025-10-08" version="1">MSSPSDSPRMRESTLLPRPPQTSAADTATAAVASSPSPSPMPSPSPSSPAPLDGGAGTPDAVDDDAEDYGQPASQDIPLTMTASTVLLNLPRDATAALATAGRFAKDKVVVRFKPVGSAPPLSGGVGGAAADVRRKITSTQKFEVVVAFVRRALKVKESESVFLYINSTFAPALDEVVGNLHQCFKDSHDQLNVSYSLSPAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS19</accession>
    <name>A0ABR3YS19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol transfer protein csr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSR1_2</name>
        <name evidence="3" type="ORF">Sste5346_007791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="224"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="500" mass="56252" checksum="C192F4887E184AC1" modified="2025-10-08" version="1">MSSELPPGRVGNLTPEQEEKLRQFWAAVFKVYQFDLAGFESGNAAEGTDAPDDDDDGAGATGLGPTSSVAASDKKKDKKKKRSLFKRSKKDGGLKDGSSKDGSPAEEPVAAVTKAVSTVDLAATSEDDKYGQSKLFQEALANQSPESIRDTIWSMVKHDHPDALVLRFLRARKWDVDKALVMLVSTMHWRAQDMHVDDDIMLRGEGGAVEEAAASTDEKTKTVSEDFLAQMRMGKSFLHGSDKQGRPICIVRVRLHHQGDQVEESVERCTVYTIETARMFLHPPVDTATVVFDMTGFSLANMDYSPVKFMIKCFEANYPECLGAVLVHKAPWLFQGIWRIIRGWLDPVVASKVHFTNNVKDMEQFISKDQIIKELDGDEDWEYTYLEPEPGENDKMKDTATRDKLLAEREHLYRAFEEATAKWVVGTNAEQIKTTREKRESVAKQLREHYWTLDPYVRARSLYDRSGMLRADGTVDFYPKLEKDETTQTNGNATAQDDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSK1</accession>
    <name>A0ABR3YSK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007887</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="634"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="688"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="652"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="728" mass="80661" checksum="9733F039642DC6B2" modified="2025-10-08" version="1">MSDSDPHRTSTPHTAVPSSPAPTDSNGSYNPRKRGRTACTRCKNRKQKCDEQLPVCSNCRRAGADCDKADVASQPLPIAYTRALEDRVAQLEMLLERQAATPKEAQAVTSPSSVHGLTHGHPDSALSEVVGIISLGNFEAPAYVGPSAGLSLAVNLGEMVQATVWKKAIPDVFDPREAAETSPGGPLSTRLPRGGVRAMTKDEMARYSIKEPPSDALGTRLLHLYLSQPHSRYPFLQPADLWTLQREHTSSSVGVSSPHLTPSQRYGIFKLYMVYAIGATLLQLTNKNMDVAPERFYVTALQHMAAAREPRTVQNIEAMALLVIYHLRSASGLGTWYMIGLAMRTCIDLGMHRRSHEQGLSAASIHARRRLFWTVYALERNIAISLGRPLSLADRQIDVDLPRATLSAYPSSPGYDIRAVDNSDNIQRAILLFQLRRIESRIHHSVYRADKPLSTLRPKLDSLYTALEAWRENMTSTLRAIATNEDDADTSYLLLHYHRAVRTLIQPFLTILPASDPYLTRCLAAAGNICQSHKRLHQSLHYGHSFIAVQTIFVAGATLLYGLWTQTHRVWSVTLADDLRACSLVLFVMSERAPWVRKYRDAFELLVGATMQKLRSGGNDESAGGDLADMATLAQGQPVRPPPPEETRSDRQTSQSTQSGPTSTHPAEGGRDEDGDVWYLVKELANWIDQDPTQGQGQDQDSSQDKDNAPVWMPDFETLQNWTSFTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSS7</accession>
    <name>A0ABR3YSS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_007905</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF25">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="10">
        <location>
            <begin position="31"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="9">
        <location>
            <begin position="196"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="399" mass="42359" checksum="6B2356E61A2A7BE9" modified="2025-10-08" version="1">MSTTTEISRGQYLQGPRSLKLEARQLEPLAADSVRIAIRSTTICGSDVHYYTHFANGSIQVKEALCLGHESAGLIVAVGSDVANLNVGDRVAVECGVPCSKAECAHCSAGRYNICPALRFRSSGSKFPHYQGTLQDFVDHPAAWVHRLPSVLDFGTGALLEPLAVAVHAVRRAGPTSTTIRAPNCKLTCLVFGAGAIGLLCAVAARAECGNDVDVVMVDIDEGRLQFAKEHCFASVVHAIRPRRGETLQEKLAIATETAAEIAALTLPDGTPVGKVQRTFECTGAESCLQSSIYATAAGGSVIIVGMGIPSHTLPIADLTAREINLTSTWRYASDYERAIEIAAGSITGSPLDGTKLPDVSLMITHRFKGLDSVQDALEMARKTRDDKGALVVKTVVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT66</accession>
    <name>A0ABR3YT66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mannosyltransferase ktr4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">KTR4</name>
        <name evidence="6" type="ORF">Sste5346_007638</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF7">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325884" evidence="5">
        <location>
            <begin position="29"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="393" mass="46123" checksum="0375666D23A970CE" modified="2025-10-08" version="1">MTIARPVRALIVAVVFAVCLLVMHFAGSSPSKSSVFKLDSHERDPNLDPTHEPEGLLRRTSKGYLPGPEGTERINATLLALVRNEELNGMLQAMGDLERTWNHKFNYPWTFFNDVPFTDEFKRRTSAATKAECFYEVIPDEHWAKPGWINEDLFQESVKMLKENDIQYADKLSYHQMCRWNSGMFYRHPALEHMQFYWRVEPKVHFFCDVDYDVFRYMQDNNKTYGFTITLYDAPHSIPTLWPETVKFLAEHPEHVHANNAMDWLTDRVRRPDHNNKANGYSTCHFWSNFEIADLSVWRSKAYEDYFNHLDRAGGFFYERWGDAPVHSIALGLFEDKSNIHWFRDIGYQHIPFFNCPNSPKCKGCVTGRLTDGEAWLNREDCRPNWFKYVGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT68</accession>
    <name>A0ABR3YT68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxidoreductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019180">
        <property type="entry name" value="Oxidoreductase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039251">
        <property type="entry name" value="OXLD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193:SF3">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09791">
        <property type="entry name" value="Oxidored-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase-like" evidence="2">
        <location>
            <begin position="158"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="299" mass="31389" checksum="BB50216A4558BFE9" modified="2025-10-08" version="1">MAVTVTTTTSPRSSQPLSTSSRRHAPPPATVAPTATITQAQPRGGYYDVLLTNPPPYSSARANAPPVTARPKATEAPEPAAPTAPPTIPASAPTTPASTPTPAAQWKQQEAPATIAARKAAEQKIVQERAALVFGSRLAGPMERANRLAEIRKRSTNIAGVMVPPKPTEPDNCCMSGCVNCVWDRFRDEMEEWAAANAEATRRLQAQEGGVAGTTGGPPKAPGTPGAPRPGGHISMDDDGGGSDTNWSMEEAAKSAAGGSKKAGWDEELYKGVPVGIREFMKQEKRLKLKHMNDGQIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY3</accession>
    <name>A0ABR3YTY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="111" mass="12546" checksum="274EBE2888107412" modified="2025-10-08" version="1">MVAFIKRKEGMSLEDFYKYWEDVHGPLVKPWAEKHGLTYKQIHTGSNAPTGVDSQFLSKYDGCAIFEFSDPNAISVAFADPEFKRDVSPDQEFFMQEQVTIMATGSTVTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU48</accession>
    <name>A0ABR3YU48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">60S ribosomal protein L37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RPL37_1</name>
        <name evidence="1" type="ORF">Sste5346_007995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="282" mass="30985" checksum="D668427DD9CBDC38" modified="2025-10-08" version="1">MSGNDPIVPEGVEAAFDAAKDAQLLTVHGIDGAGCGWLTIRLLADWLRFCTINPESGKSDIGVVIFSFKHNFDYYSNHLASFGINLTWHLEQGHLQFLGNQFLSLVADQATDPPTPPSLTFDASMDMVMDMASEMREKYDRTVLLLDNPEMGLMLTSDDDDVRVEKWLMAIDAATYLYHNAIVSMVVEFAHPVHFPVTEKTADATATAVCSLNLNSKMAITVRPGDSQAGSGRISIVYRMGYEVNVGEDRSQQQSDDASNENLNVSVGNNGLNIEIMGQPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUV8</accession>
    <name>A0ABR3YUV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044958477" description="Post-GPI attachment to proteins factor 3" evidence="7">
        <location>
            <begin position="33"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="335" mass="37966" checksum="D3BCF559DD8BF872" modified="2025-10-08" version="1">MPSVLTRGLPASAFVLLAVVVVVLAILPGVAASVGDRLPEFRECLEACCVCKAENCGPNKPATPIPFHLRLLLWDCASECDQTCQRIITGHRLAAGVNVVQFHGKWPFFRLFGIQEPASVIFSVGNLWAHVAGLRRLRRLVPATYTLRPFYIGFGTVGMASWIFSSIFHTRDFTLTERLDYFAAGASVLYGLYFTVIRVFRLDRPTRESVRSVWTAVCVCLYLAHVGFLTLIRWDYGYNMAANVACGIIQNALWSWFSYREWTRTRRFWAVWPGIAVAWVMLAMSLEMFDFSPIWGVFDAHSLWHLGTIGPTILWYNYLVRDALNNIPGKERLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVJ4</accession>
    <name>A0ABR3YVJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1892004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045877286" evidence="1">
        <location>
            <begin position="24"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="131" mass="14498" checksum="DE9373382B8FDC93" modified="2025-10-08" version="1">MHPLFVRIAAALGVLSHITPSTAEFSSHCTDICLDEMHPNILVTRCSSASYFGGAYKWSEFDLNTIFAYRAPYIVYEENGNFSVDSHPFHQYAPSTTNPEETDASLYNVAGDICYGDKFGPICGKDTPRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWB9</accession>
    <name>A0ABR3YWB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="721" mass="78687" checksum="BB9A9D148A5C7CA0" modified="2025-10-08" version="1">MGLPLYIAPVESDLRNKYSAARNSPTHGPNRIRRTRRSTEALVESRRRAILTATANNLPHLDNFREQQRQLDEVQEFIERQHQRQHGSAPEWQRTRPPRVRESLAAPAANPTMQDLNENATSRSSRERIYEHYLGRATRDREQARASASARSPSANPTNPGPGARQEEYRRWFHEHISSHREPPSALLSEGVSSLMTAAITDDMEDSTDRYNRELMAALGSRLARTVGSGIAHRLTDLTSISQPVDDLHQQQGPRASVDTEDPEGQARAMNRARRALRRASSLRRVTNASASASSRRPTVGWSDSNDRAASRSRESSQSRIFGDASQIPNGGTSTPGTNGRATPDAAASRRHAWGVGYLDLNGNRRLPLTDELRREEIGAIGMWDEDGNQLEDGYGVPVDPVDGLGDRRRSPSPEVNSWDTILTTLTADPQLPSVGSSFASSTSALAAATAQGQSAWATSSQPTVTQTPVVSALPAVPSPVTRGQEDDDNNNNNISGSTTGSTPAPILVEMSRSPSWLAEDHRALTDSAPSGTTSAGTSQRIRSPFTVVSADADTADESAVMFNGLEDEVGDNCEDSEMNDGVRRDGEEEGAYDEEEELEAEEARAYLMGLSDEMPARRPGQTSNSMERMFHFENRERPVRTGFGGARPESNSTSANTGANNGNNAGNNSNNNNNNNTEETLDLLGIGGMQHIVRSLARREDIPDEWWAEAGLSRTLPREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWT1</accession>
    <name>A0ABR3YWT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="552"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="155"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="608" mass="68865" checksum="08B924BB7D4DCBC2" modified="2025-10-08" version="1">MASVWSNRPAYDQVPANEGAAEEMEERKDEITMTEGRESEDHLETSSGSTTDVDTEAEAGFPFPREKARFTKSRAGGFISAALVLPTIALRLAYLCWLVATHPLRRLVGRGRSSALSEWPALFNQLGAFKVLVPSFLHPVDAATAASPRKMHPTAWLDGLRGMAAFFVVWNHLSVLWFNWHIHNGYGINEHEHWLIQLPFLRLAISGPPMVAIFFVISGYALSYKPLKLSRMGKFADAYEAIGSSTFRRWPRLFFMPVVITFICACMTYLDMYGTKGWGGVAFPSRRPPRDGTFWGQLEHWWPSVVMLIDPFSKNMNRGGRYAYDMFLWTLPVEFECSLMLFLCQACFNRIRPNVRVVFMFSLAIFAMKYVYWQYFLFLCGMLICDLQFASQEEKARSSSAVSSTSISLPSTSVFAVAAALYARARRFTSRHQTAIGIFFFILSLYILSTPEAIRGAVGTPGYKTMIKWVPQHHQKTHNTDYFWVPIGAALLVYTVDCTPVLQRIFTHRFPQYLGKISYSMYLAHGPVLFTAGHYFVRQTTKLTGLQGQVRYGLGVGLSAIPFWFVLICLADLATRTLDKWSLSLGRLLYERLSSRGPEPEAVLPRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY66</accession>
    <name>A0ABR3YY66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cyclin-dependent kinase</fullName>
            <ecNumber evidence="1">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CSK1</name>
        <name evidence="8" type="ORF">Sste5346_006512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF576">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CSK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="107"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="429" mass="48294" checksum="1DB90151D4AFA6D5" modified="2025-10-08" version="1">MSAPTPYADSTPDIPSPRCVEPEVDWRADVDFMDRYNNVRQIELSRQPREMKATALEIESEIYNNSRSKHDYNANIQGVIDAGEPMETSEGDTSLESVGNGIVIGQYTNCEEIGEGVSSKVYVSGTVALKVRKEPEDLPPHNIGREARIMETLGTRRDNNGGLTRCIHLESYFDSPLGPVLVMPFMPLTLEMVLKDDTHDCSPHSKLSQKRLFHIFEQVFSGLEYVHSFGIIHRDIKPSSILLSSLDGSAVLSDFGASWHPEFSLMVEPVEPETQKCLDVGTGRYRAPETLFGNHAYGTSLDMWSAGAMLAECARPYPHDPLFRSLAAHEDGNQLGLILDIIKKLGTPTHETWPESTTFRTPPFEMYNHFETRPWAEILADVNERIQVIVSKLVRYQSTERLTATQALEEIQKLQNPTEEETHDEEDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY71</accession>
    <name>A0ABR3YY71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="326" mass="35040" checksum="DFE9500A32AEF483" modified="2025-10-08" version="1">MAQPVKVVFGGNRIGNREPFTPSTDLLAAFKILKAHGVDTIDSAQNYNNSQATLGEVHAGDQFALDTKWGASRPAGAPPGGGPPGAGGPWATKEHIVNSAKDSIQKLGVKQVDIFYIHRPDPHTPIADTLAGVQEVYEQGLFRRFGLSNYNAVDVEAIYNHCVEHKYVLPTVYQGTYSPITRFQETTLLPTLRRLGLSFYAFSPSAGGFLGKTVVQIEESLKNPDASPRGRRYAENPVFRGALAQWNAVADKAGVPPAELAYRYIAYHSALKKDLGDALIIGAGSLEQLEETLAAVEKGPLSGEAVAGAHAVWDAIKHEPSAASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYW8</accession>
    <name>A0ABR3YYW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106627" description="DUF8021 domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="3">
        <location>
            <begin position="154"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="30306" checksum="A77FC30439395043" modified="2025-10-08" version="1">MLSSLFFLAALHTVVAAPTAGCSRNQLQAVADSVVAAQTAGNPALVQPAAAADAVFTENRQPSSSLASGILSHLLKPDHVRSSLDTTQCATYTEMIVAGSKPYEIGVQVFLSADASSVQRVDTIYTSTGDWLFNITGTLYWASREKWDTIPEDKRDTRATIQAAADAYCDIFSNKSVVVPWGKPCARLEGGSYTGKGTADDSCNVGIPSGVSLTQRRYVIDETIGAVDVMMAFADLPDSHDFRVEGGKLRYVHTMTVMTGAKGKSSGGKGKNRRSLTGDVKVSAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ91</accession>
    <name>A0ABR3YZ91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="449" mass="50130" checksum="33FB59C554192783" modified="2025-10-08" version="1">MSTESAPVSAPGPAPAPAPAEPAVGSAQYARLHMDADTKAVVTKLIDKEHMAEFLASDPDKGEHNPQDYNYKTTTFPKRFSFIFADMLIAAAPLAAQRTISATAPVQPGLEISATAAATATLIDKMCPYEAYAAKRLAEAEKDEDRKYDEDNDKSEDEDDEDGDVDDTDVEVFVYYLWNVFLDVVRAVPYDSPLQYELLGSDLEKAVTLTQALHGANPYVHPKKPAEYSPEALDSKRRWLESCVQEWTSFSTFKAREILTDPSRSLCWMRFGIVDIAEGLERSPAKLLAGPGGQINEPGDAEAPLRVLCFSNSLRVACHWLLLVGRAIYRLAIRDIDDNLDKGTAFWDDEVSLRIIRHNMYDLYYENGGTKEGKRGPRWLFWKRRLETLGSNNENDPNSGIRLGLDDELRAIARLTAERMGEHKAGMDAEIAEKGWANVKKEYGEENEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP1</accession>
    <name>A0ABR3YZP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039601">
        <property type="entry name" value="Rrn5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28079">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28079:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="138"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="694" mass="77382" checksum="37552B63D3AEB770" modified="2025-10-08" version="1">MEGRRDMESESSDYQPSDSESSPEAAEPSVVEEPEIKDEEEDGSVQMGNVEAYDGNNSNNYDNSGDGTSSSIYRAGLKRTRERTFSTPLVDDNEPQAKKRAKIPLNKHYMDLLQDETDDARRKYISEDLPELSETKIGLTVWTAEEKEMFFESVGRLGTDDIAGIAARLHGSKSEVEVRHYMHVLKECAQGKKHDIRAPLHRPLLSDFPVATEISDACCDALQKTADILAQRERDQESKDEQSKWGLYWLVTGDNCHDLSKVALEKVGMSTTDDDASNQSPLPTVGPQAARLTQLSKDVAPKAPPMLSLLNVPTMLLLSERVFMNGVEEDANYLGLGDELPAIHMSAVHDLYSLVYAITQRLVATAMHICRSRDQATSKIPRSVKKLVRTRDVRAAVASLGMKQNSQVFWARCPRRLGLNVSRSAVPFADTDGLGVQAAPIDDEASKDGPEGDPEGDSEDDSEESDSEEESSEDSSSSDDDDDIISTYGEVERELLPEGFEYFTSQQSSSHNINSDEDLANSEEDDDESDEDSSDDSDDSDDSDDSDREQNDEQAIITEQRVKDEADEIIHYTATSYPTATWAQTSLKNRIRDELKEEEYACAVDDHASRRDELYLWAIVGERPPPELGLDEFDDNATPHVEGFSTDTRRFPVDEVIETGRDWRDKLNYEATWEKAAAEAQKAAREANEQAKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z149</accession>
    <name>A0ABR3Z149_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="341" mass="37375" checksum="077E44C44B66331A" modified="2025-10-08" version="1">MDHTLPKGSLVLVTGANGYIGSHIVDVLLSLKYRVRGTVRTIKNKTWLNDFFDSKYGPGVFETVEVPSLDDTTALDRVMTDVGGVVHVAADVSFSSDPHAVIPQAVETTLNVLRAAQKQESVSRFVLTSSSSAALVPKPNQRGIVVDQTTYNDAMVAAAWSDDTPEATRAYCVYAAAKTESERAAWAWSEKEKPGFVLNTVLPNTNWGRILIPDHQRGSSMRLVRNFWDGNHSALQLIPPQYFVNVGDCARLHVAALLNPSVHHERLFAYAAAFNWTNVIGVLKTLRPDYAGFPEPPPDEGRDYTIVAGQKRAETLLKTTFGQNGWTPLEQSLADGIEGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z201</accession>
    <name>A0ABR3Z201_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Secretory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEC63</name>
        <name evidence="12" type="ORF">Sste5346_006003</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
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    </dbReference>
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        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="106"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="656"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="658"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="718" mass="78479" checksum="AA1E9E72915F77F4" modified="2025-10-08" version="1">MAVDYDYDETGDLWPFFVFTLAVIITLPLTYVLLKGLGNPAAVFPRVQSKFRHGHSDLVDAERAKYRRQQRRLGLILAVAVGWATMGYMLYLIQFAEVAKVERIWNPYDILGIADSATEKVIKTAYKQLSRQFHPDKRKPDASKNETIEMLNDRYVDISKAYQALTDEEIRNNYLLYGHPDGKQGTSISIGLPKLIITDGNGKYVVLLYFLLFGVLLPYVVGSWWYGTQSRSKEGVLMESANRLFHEYADDIDEAGLVSALSTGKEFDAVLPGDKADSGLATVEARITAPAAAAASADDEAATTASSALTVAGLSTADREKLDNLDNGVRRKVLALLWAYLGRVDLGDATLEKHKFEVAPIANTLTRSFTAIALAYGNTAPVIASFKAGQLIIQALAPKSSPLQQLPHITPAIAKAIEGDSTVTMPIQRLMDLPDAKRRKIAVGSGRLSADQYEEAVSVAKQLPQLRVAKAFFKVPGEKHIIPSSLVSLVVKGRFIPPGFAESATEVDPSELLDADPAEDDMDALLGRKPKTIVGRNPDGTAITSDAGNGKPNLPPLAYAPYFGRDYSPRWHVFLTDSKQGKMVVPPFTFTAFDRPLFEEDGKTPTFNMQTLKAQFMAPPQAGQYTFVMHVMCDSYIGFDTKTEVTLVVKDASAAAEMADEDEISEPEEDSIAGIMNAAKGAPVKKAKYESDEEDDESGTDEEADDTSDTNTDTEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2P5</accession>
    <name>A0ABR3Z2P5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247706" evidence="3">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="98"/>
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        </location>
    </feature>
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            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="29059" checksum="3595883EE8CED7DA" modified="2025-10-08" version="1">MSGTYIALIVSLGLLTGDAVIELAYITSMVAYLHGGAPSGTFVVNTPATHVANEGSQPTYEIKGKPLHMLVNQGHTSNGAAGSAIVLIGIVGVLALFARARFPGRRFTRFLYNFWMILQIPCFLLTLSALGYTFAVTNKHRNQIINQNVAYASQPGPYALDQWTPQNWFSAVLSQLDLADADLRSNLAHHLRIMRGWQYNLIPLFLLQLAETVLAIVDWRAWKRTGGHNGGQTGCTPSWSANGYNNEKYQGQGDYNNGADPQQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3L2</accession>
    <name>A0ABR3Z3L2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alginate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alginate lyase" evidence="4">
        <location>
            <begin position="54"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="420" mass="46035" checksum="A4762EC7A6C68E69" modified="2025-10-08" version="1">MADYIPQTVTLDGRELASIKARIKTGADVDDALRNALDLLTTEADGWLTEGPWSVTQKTKAGPSGNLHDYVSQAPYYWPDPARADEGGLPYIQRDGQKNPEVLTYTDRIYLEKVFRSVYVLALAAYYTDDTRYADHAALVLRTWFVAPATAMRPSLNHAQLIPGINTGRAIGIIDFSQSYASVLDAAVLLRAATSWTDEDEVGFKVWNTTFLSWLVDGDFGKTEHAEHNNHGGFAAMLVASIAAYVGDTEQVAKEVAFAVEEHVPKTITADGQQPAELARTRSWHYSTFNLLALTRLAMVAERAAELHDSRAEQTQEGKRAERGQKLWPSLFAAIEYVLPAATGGEDKWPHPDLQFEQFAAADFVRAAAAAGHEPSQKAVPLLQMPPDGDMWPLRPAPEQLDPVRAPRQTPGAAKPGVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4D0</accession>
    <name>A0ABR3Z4D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="267"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="699" mass="77750" checksum="1F13D6B943AB0A50" modified="2025-10-08" version="1">MAHDNNPIAADTSLHANTPLAFRRADGSRREFFFDDRTHSLPHPAASLFLEEGSSTHGGSGEHGSYRQRRPGSAQHPRNVLRPFRNRHGEPAADIRFIRETRQSVCRDGVDRSRCSECRRAVTSTTKTEVKTTTKAKGKSAAIAEISPNTVPTTTTPAVASATPEPEPAHRWHMMSPQRVFRDLVMSDVAEPLQPNLRDALLDAFNATVDLQQLQTRKVQSDTPPKTPFNLGRPLLPSPPPSPTKAVASESPIDEEGTVETTAPTEFHYFSCLPYEIRRMIWEQALPFRVLLREDLQSTTYKSVRRVFRPASHTRSIEMLWQSDLFYVCTEARRVVEAAYGGPKHNSPPTVIMSDDGPQPPLVRQITSPARLRSGRDVLYYPWLGAEAIREHSSAGFSGGGLWVLGRHHDQQQQQQSPYYHGHSSAANNCSWMFKYDGSAPRNRTSPPPLTAPAPITSVPYAHWASQLRLLRLPVSTVALDAAWIDRSHMDTITWAAGVDLSQDDDTQDEGNGEEPVAAPVSLQVVVADLIIPVKIRLDLQSGITLAQRRLLQQHIAPQPWLDARSFQRLLVEGRGRPASSSSSSSSSQQGPIEAPSANLNGMDFTVLVDLYDDWRIEELLSLQTINMDEDSVLNKAACHRCIACTRREWEARSTENRSRTGGNSWTNKFGPVVGQLLQNLCRPTIVFSVVLSFVDKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4V0</accession>
    <name>A0ABR3Z4V0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diphthamide biosynthesis protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DPH4_1</name>
        <name evidence="4" type="ORF">Sste5346_005126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053232">
        <property type="entry name" value="DnaJ_C/III_chloroplastic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45090">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ 20 CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45090:SF4">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="208"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="339" mass="37464" checksum="CAD058A4A432BAEE" modified="2025-10-08" version="1">MPYSTEQTAYTFFGVSSTASPFEIQQAYDRAIRRYPPDRVWDRPMASVSKTGQQDAERWYAKISTPDARQAYDAMLAEKNKKNKLDLSFAVKAGPSMVKEMSEPETEPEGESIGEQDTIQDSRHDGEDDGDSGDDDDKKDSTPPPNKSTPITLASLDNATGSPYLYRSRTRTLCALAILWLGILIIVYGTPSTWPLYTQVSPFSSVPSPYATLGLPKDTSLTAVEIRAAYHRAVLSHHPDKCGGDANNIIEVTTAYETLSEPYSRCLYERAGLVQAWACAHLKAEEEVDVEAGVEKEPAAGSVGRPQTGQVAVFTSLHNLWQRVWHRLAKWLVRVAGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z598</accession>
    <name>A0ABR3Z598_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cerato-platanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005233</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850:SF2">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046028635" description="Cerato-platanin" evidence="4">
        <location>
            <begin position="22"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="28816" checksum="1B4617EE5AEBB841" modified="2025-10-08" version="1">MHSSIRAWASAVTTFVATVSAATTSVPVTPHASYSSSIGVLGCKVNTNRIAYWPMAVDCNNICVSLSYEGRQVYLLRIDQSGGAHDVSYDAWNYLITGKSATADPTAGGAIQMDTENVDASKCAGLINTSGSKLPLSAANSMNFLNSCLEKQADGNDSWVASNYVLYNILDPICTYGYNEVCTLRDWPDQNQATCPNTLGDPVSLTSQPVYNIEYPTGKKVLAGSSASSSSGATPNTIVAASSGGCTNMFTCQPLLFLAFGLCAVLQSFFISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5D6</accession>
    <name>A0ABR3Z5D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-binding protein cassette, subfamily B (MDR/TAP), member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_005683</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="831"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="876"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="949"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="981"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1065"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1096"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="129"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="454"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="833"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1158"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1404" mass="152001" checksum="AF2CF478B3D3068F" modified="2025-10-08" version="1">MAADDVSDKAHEAAASSPFEKGDEAAPAVIAPAPAAVPASKYGSSHADDSSDEKPTPAKASGQATPLDLTKIDSKVVKVPDAAEKEDPYGHLPADEATILRLQVDTTTVKVGFGTLYRYSTRTDIAILVVSAICAIASGAALPLMTVIFGNLQGSFQGFFNHQLGRDAFMSKLSHLVLYFIYLAIGEFVTTYISTVGFIYTGEHISGKIREHYLESCMHQNIGFFDKLGAGEVTTRITADTNLIQEGISEKVGLTLSAAATFATAFIIGFVEYWKMTLILVSTLVALVLVMGGGSRFIVKYGKESVNAYAEGGSVAEEVLSSIRNCVAFGTQDRLAKQYDIYLTRAEKAGFRVKSALAMLIAGMMLVLYLNYGLAFYVGSNFLLDGTIPLSKVLIVMMSVMIGAFNLGNVAPNMQAFTTGLAAAAKIYNTIDRISCLDPSSEEGDKIEKLKGTIRLEHVKHIYPSRPEVVVMEDISLVIPAGKTTALVGASGSGKSTIVGLVERFYNPVQGKVYLDDHDISTLNLRWLRQNIALVQQEPVLFGTTIFNNIGHGLIGSKHEHASDKEKQEFIIEAAKKANAHDFITALPEGYETNVGERGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTRSEGVVQAALDVASEGRTTITIAHRLSTIKDAHNIVVMSQGRIVEQGTHNELIEQRGAYFNLVSAQSIEVVSDLTAEEEAIDAEMDEHLLRTISSANKGNAAASASGSSVTAAGASGEASASKTAAVADAASGKDLEAGFLADPDDNIQEKLKRSDTRKSVSSIAAQARKSEDAETKYGLGTLIKLIASFNKQEWKLMLIALFFSIICGGGNPTQAVFFSKEISTLSVIITPLNRDQVRHDAHFWCLMFLMLAIVIFIAFSVQGIIFARCSERLVHRARDRAFRTMLRQDIAFFDKDENTSGALTSFLSTEVTHVAGLSGATLGTILTVTTTLISALTVSIIIGWKLALVCTATIPLLLGCGFFRFWMLAHYRQRAKKAYEGSASYASEAITAIRTVASLTREEDVLHHYRENLAEQLKASTRSILKSSSLYAASQSLTFLVLALGFWYGGKLLSEGEYTMFSFFLVFQAVIFGAQSAGTVFSFAPDMGKAKQASAELLKLFDNKVAIDSWSEKGEPVTSHEHIEFRDVHFRYPTRLEQPVLRGLDLSIEPGQYIALVGASGCGKSTTIALLERFYDPLAGGIYLDGKEISTLNVNEYRKGIALVSQEPTLYMGTIKENILLGAVDDKQVSDADVEFACREANIYDFIMSLPDGFNTLVGSKGTLLSGGQKQRIAIARALIRDPKILLLDEATSALDSESEKVVQAALDKAAKGRTTIAVAHRLSTIQKADIIYVFDQGRIVEKGTHTELMHRNGRYAELVNLQSLGKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5J5</accession>
    <name>A0ABR3Z5J5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heat shock transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CTA8</name>
        <name evidence="9" type="ORF">Sste5346_005500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="8">
        <location>
            <begin position="215"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="504"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="885"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="762"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="937" mass="98249" checksum="C928281467A302B2" modified="2025-10-08" version="1">MSPNPRKRAAPGDPPIFPMAANGQTAFNPAAQQDQLLQWSGGLPDGFGNLSQNANNYMMGNQGQFFQQQLRQQQAAQQAQAQAQAQAQAAAAPQQLPLQSAQPQQLHIQPQPVGGQIQPQPTSTAIARRPPNRALIPSVSRNAFDPSADWSAFGDDAGVLTANHNAGGHIRAGSGGGSGNNNNGGTGLPGENESIEVLEERAQRIKKDAQAKRKQIPPFVQKLSSFLEEAKNTELIRWSENGDSFIVLDEDEFAKTLIPELFKHNNYASFVRQLNMYGFHKRVGLSDNSMKASERKNKSPSEYYNPYFRRGHPNLLWLINKPKSGSKAKRGKKDDGEGDSDEDGNLDEPSMMAHHASIQGMGGSQQGRGGYAAPGSGVGVGGGVLGAGVGGGASGAGGAVALDANGHASGELGPLQKKDFQIIKDELSTLQTRQAQISKVMQRLQYDNAQLQQQARLFQNMHERHENSINAILNFLANVFRKSLEEQGGVQGVTELLASILPNGQMPTGSVVDLSDDFDPRRPAPQPTNLSTPPMKRQQRLLPPIPAPSASTTAASTPQASGSGSGGVGARGSNARSSSVLSPNQQHLGTGGYGHAGQAGHQPAMGSVTELFDSPGDNNNNNYLQHELQSNPQEGMMRIINDTNANTPASGSAIDLLEAAAGTPTNMSTDQRDRVIGLMNAQGNNPNMGGQQQQQQPNVANLARNTPLTGPGGVPLSPQVPMTIPATAAGGAPPNMAAGANTSLSPILGNMQAIPPPSLQDISNTQSEIEALQRLQEEQNAKISDLTQMLGPLSPSGRVPGIDEDAVSVGGSNNPGMQSPGYFDLNQYLDTNAFGDDFNFATDDLTGSNAAAGGAAGQAAGGTGGAPFGDDFNFTIDHTANNANSDANANTNGVDADDGGNGLFGKSPSPALTEEIPRTDLSTGNSPNPAVKRRRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6U9</accession>
    <name>A0ABR3Z6U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Presequence translocated-associated motor subunit PAM17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PAM17</name>
        <name evidence="14" type="ORF">Sste5346_005000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the PAM complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the PAM17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013875">
        <property type="entry name" value="Pam17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021:SF1">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08566">
        <property type="entry name" value="Pam17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="57"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="293" mass="31522" checksum="9DD1D96D83B82CEC" modified="2025-10-08" version="1">MLTTTAPTLLRPGLAVASRTKPAVTTATKTSAAFILRRPTTISMAMPKMQSRMFAAPAGSLKRKITPTTPSTFRRCASSTPNSTKTNTSSSTTLHSRPPATGATRNRDAAVDAAAAARIAERAQADARVNAATSNGPSTKDLPPLDWNTFFALRKTRRRIQVAFSVTGGLTGGLVGGLFLGSGVAEPILSTIPLDPFLTLGLMTFGFAALGWLAGPSIGNVVFYAWKRQYKTQMTLKETQFFARIKRNRVDPTASSAGNPVPDFYGEKISSVAGYRQWLKDQRAFNKKRTTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7E8</accession>
    <name>A0ABR3Z7E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="29069" checksum="EF91FF358FC0724B" modified="2025-10-08" version="1">MASARINGKTIVITGASSGIGRSTAFEFARIAGPGSTIRLVLTARRLDVLKEVAAEIQKEFGEKQTVHVLPVVLDVSDPDAVRSFVPSLPEEYRDINILVNNAGLAKGFARAPAIAEADMNVMFATNVTGLINMTQAVLPIFQARPDGGHGDIINIGSGAGRQPYAGGGIYCATKAALRSFSESLRMELVNTRIRIIEIDPGQVETNFSVIRNYGDKAKADAIYANVEPLTPEDIAEVIVFTASRRENVVIADAMIFPSHQAGGGVMYRKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7G4</accession>
    <name>A0ABR3Z7G4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Manganese/iron superoxide dismutase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="149"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="276"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="333" mass="36088" checksum="08388E26AD62703F" modified="2025-10-08" version="1">MFRPRLRTPAAFGGIISSGASSLLARQSAQTALAPLSQALRSRSIHNLPVSRHDAYAGVPNLLSAEGYDLAWTQHMSLMLNRLNQLTAGTEYENLNLKTVVQETARFPHLASTFNHASMALNTDFFFKQLLPASQPGAAATPSREIPSTLRAAIEDNFSSVETLRLEFAAIAAGMFGPGFIWLVKANNLHQSGRGGDNLRLLTTYHAGSPFPGAHYRRQAVDMNNVGAETAEGNDPAAQWLADQGRAASYPTPPTQPGAPATYPQQVDKRPPGGVEVIPLLCLSTWEHVWLRDYGLGADGYGGKAAYVDAWWKAIDWQAVDSLANLTRPKLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8G6</accession>
    <name>A0ABR3Z8G6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004526</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF46">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="479" mass="50893" checksum="E9262D0CC6C1E60A" modified="2025-10-08" version="1">MTFTPPKSVLILGSGVFGLGTADALSKRPEFANTTITVVDRGSGEEGGEDASQHFPARDAASIDSSRIIRADYADAAYAALADEAQAFWRGAKRPADAVDDQDYIGGAGRYTESGLVVVADASDTKKANGGKKSGMDYVRESWANVQALASKDAYLATKLKELPNPEAIRAVVGTGGTTGDWGYLNGASGWANAEKSMAWYQKRVQKAGRVNFVRGRVSSLETEESGDKKKVIGVRLEDGRTLTADLTIAATGAWTESLVGGTSLAGSLAATGQVLGYVPFANDEERAHVAKMPVVLNLTSGLFIIPPAPDSRELKVARHAYGYINPTTTKSGASKPVTHLDDPNLNIPAEGADDLRRGLRQMVAMTGLVDRPFAKTRICWYTDTPTGDFLVDYHPDYEGLFVATGGSGHAFKFLPVLGEKVVDCVVGQRPAAFADKWAWRRTAQNASGLNWAAVVTEDGSRGGKPGLLLQEELSKSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P8</accession>
    <name>A0ABR3Z8P8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetoacetyl-CoA synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF4">
        <property type="entry name" value="ACETOACETYL-COA SYNTHASE (AFU_ORTHOLOGUE AFUA_8G04770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="3">
        <location>
            <begin position="43"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="122"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="702" mass="77184" checksum="83E13B8E316DFEB5" modified="2025-10-08" version="1">MSSQTTGHELPRKLWTHPRPTETAMFRFMKQAEQDAQQLFPDYDALYQWSIQHPSAFWRSVLAFFPIVYSGTVPDPVVDEHARIDTVPKWFSGVQLNFAENILFTGTVSGARSCPCPGKEDDKIACTEVREDTPHEPVHITWAALRERVGRLEQAMKAQGIRKGDRVAVVGSVCTNTLVVFLATTALGGIFSSNSTDLGPAAILDRLLQIQPKLLFVEDYAVYKGATIDLRPKTAALVAGLRRDPEFQGAVVSPRFAEAADLLAVPLCQTWDAYVAKAPSALLVFEPMDFAAPMIILYSSGTTGQAKCIAHSVGGIVLSGHKESTLHRLVDHTSTQLQFTTTSWMMYLSAVQLMLTGARLVMYDGHPFTPDTTSLLRLAAQEQVTHLGISPRYLQTLQSGGIVPRRAFDLGHLQVVTSTGMVLSEALFAWFYDTAFPPSVLLANISGGTDIVAAFGTCSPLLPLYIGGCQCISLGMAVEAFDADGRPVPPGEAGELVCTRPFPTMPVRFWGDDNGIKNTKKNNNVGSRYFGSYFDKFANVWTHGDFISFHPHTRQVMMLGRADGVLNPSGVRFGSTEIYNVVDDEFADCIADSICVGQRRPHDTDERVILFVLMQPGKQFNRQLVQNIKQRIRARLSRRHVPSFVFQTPEIPVELPVKHIVSGRDIKPSSSLVNPGCLAFYYAFARDDVLGGKTGAGQMAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S8</accession>
    <name>A0ABR3Z8S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004271</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="524"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="688" mass="75303" checksum="A37B0895FCC66966" modified="2025-10-08" version="1">MAAAMYPEPERRRNRGFLGSDSSALSPQDRQDRSQLRYELDLNSWNLRIWGVAASGFLTDSYNLFATNVILASISFVYFPESNFNYVGTLINVFTLLGSVVGQLTFGFLADYYGRTRLYGIELILVIVSTIGVATSNYGYNDLSFLGLFIWWRFVMGIGIGAEYPLSAVITSEWASTSSRATMLSSVFLMQPVGQALAQLVGVWVVLGRENMYHLQEMQCGINDKYAEECKQAVDGIWRIVIGSGAVPALLAIIFRFFLYDCGLYTLEVKNKPGTAFRDTQRIYGAPVSMMGSGGGGGGDSINGGAVSLYSPGGAHSDEPMPIQFSIQDLKNYFIRDGNWYYLLGTASTWFFLDVSFYGFSLDNRGVLADLWVTRSPPELNSTLGCWNSSLEGGNSTLPTWSAIGHLPIWQTDPTRPCNTIYEVLIQQAKQYLLTVSLASIAGSACFIFAANRIRRRQWLTVSFICLFFLFIITGSVYYGVGHTKYAPATVTMVAVCHFAFNFGANTLTFIIPAEVFPTCYRCTCHGISAAAGKLGSIVAVLIVYGVSVGYESTTRQGLLFLLFGTFMAFGAVFSWAYLPDVQRIVGNRRPGGVGGPGRPGPIGIGGIDLGLPRDVGADRNGRSVHGYGRRYGGARNGTALETKNLEDLGEGRAKARHEGEVITIRDKWTEFKRRRGSRRLGSSSGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAH3</accession>
    <name>A0ABR3ZAH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="309"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="574" mass="64302" checksum="4B961743016BB8C0" modified="2025-10-08" version="1">MIVERDVSITVSDGITLKADVFRPDDDQSPAPVIMNMGPYGKGVEYKTGYALQWKWMLERYPDILPGSTKSNMTWETADPETWTAWGYAVVRVDSRGAGRSPGVIDLFSPREIRDLYESIEWAGVQPWCSGKVSLLGISYYAINQWLVASLQPPHLAAIVPWEGCSDFYREQCRHGGILSNAFLESWYPKQVIPAQHGNGNGPDDPWLQQKATGPEVLSEDELKANRIEPLVHPVARPLVDDWYRERTPDWSRVTVPLLSAANLAGFGLHARGNFEGFGRAASTHKWLAVHPGRHDVAFYLDHAMQLQKRFLDCFLKGIDNGWLDEPPVLLRERRPDKELGDEVRREPAWPLPNTQWTKLHLQASSQALAAASTATTQQEQGSITIDAMGDEAVFRSDPLTVTTEITGPMAVKLFMSSTTADADLFLTLQGWSPDGTEVEFQGAWDPHTPLSMGWLRASHRKLDAALTKPYRPYHSHDERQPLEPNKIYELDIEVWPTSITLPAGYYITLRIGGHDFQRASALADPSLNWREKGAGPFLHNHPQDRGSDVYAGKTTIYTGPGQDSFFLLPIIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL8</accession>
    <name>A0ABR3ZAL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003956</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="82" mass="8787" checksum="78FA8112C8041F30" modified="2025-10-08" version="1">MTCACYLRGFPIAEMSAVVDYIVYMTYDLHGQLDFGNAYSDDECPGGNSLRSHVNKTETLGALAMITHAGVPANKVVVGMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBG6</accession>
    <name>A0ABR3ZBG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="296" mass="32947" checksum="2FB932BA380C9306" modified="2025-10-08" version="1">MAPGSPILIPQRSPTRKSSQELPLFPVPRSNNSDGPPLRNHQKQSSSVNEFSGTNLLAIPEPDPETANLTPSLIADEMDVDNGTTTVDEAAAQQQQQAQQTQQAQQAQQAQHAQQQAQQQQPTLAAPQPIQFSQSRSVRSPVRTPELQTTLPQRQAPNGNGQGYGYTNGHQSQQQQQQQPPPQMQHGASQARESSPSTPGHIPPFDWEEFEARYEHALAEMNGEEKELLEEFDRLVNYFNVWASAATAHDDERAVKRLQTRERYVKIAEQSLGQRKQHLTEVVRAFQSALALLSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBU7</accession>
    <name>A0ABR3ZBU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="155" mass="16933" checksum="07D4B0D5B2943B09" modified="2025-10-08" version="1">MSTRKRKQEQEEEEEFLSLPSGDEEEEEFEDEEDYEEGDEDDDDEEEEDEEGDEEDGDEGDDAAARPAAPPKKKQKVASAEGGEENGDDAEADDAEEDEEDAEEPEEPEELDDDAEAEANGDADDDLVKKAAAKTDAPVVADAEEEVAAGGDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC77</accession>
    <name>A0ABR3ZC77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-repressible alcohol dehydrogenase transcriptional effector</fullName>
            <ecNumber evidence="2">3.1.13.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CCR4</name>
        <name evidence="2" type="ORF">Sste5346_003684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="50"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="194" mass="21890" checksum="5FCF9B7FF6B58168" modified="2025-10-08" version="1">MVTALIMDFVTKQAEKYARWPALKDKKMIEIPGVEKDPNPPECAPSQEYRSNTDIPLFVCGDYNSTAESGVTELLRMGRLAPDHPEIAKFQYGNFTRDGIEHPFSLKSSYQHLNGTPDELPFTNYTPGFANVIDYIWYSTNSLEVVDILGPPDAEYLKRVPGFPNYHFPADHLQIMASFVIKPRKDKKSGTSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC92</accession>
    <name>A0ABR3ZC92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Helper of tim</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HOT13</name>
        <name evidence="6" type="ORF">Sste5346_003953</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016694">
        <property type="entry name" value="UCP017292"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF1">
        <property type="entry name" value="HELPER OF TIM PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017292">
        <property type="entry name" value="UCP017292_Znf_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="116" mass="12958" checksum="105474509B4026C9" modified="2025-10-08" version="1">MVNPTSQPAEDVVVHGVDVRHNTQCAHWHSDRDIIAIRHKCCGDYYACISCHEALAKHPPTCWPKSERDSVPVVLCGHCRRQLTISEYLSSGNACPGCQSAFNPGCALHYDLYFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCA8</accession>
    <name>A0ABR3ZCA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17242">
        <property type="entry name" value="DUF5315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="387" mass="38743" checksum="69D71AE7FAAA3AEB" modified="2025-10-08" version="1">MSQWTKGKFKQRGPPPALFSHSSPAASNVSLAGGDTGSGTAAGGAGTSGHGQPSNATGSTGLGLSAVSTASGANTAATSRMPSLPTLQRTTSRLRQEVSNGAGGGGSSSGGGPPPALSASSSAAHSQAVGHQGSSLLAPGGGSVATPTGSGTSATTAAAATKARAPGTSFSLPLPLRHASSTRATDRTDALWAEMQATLEEVELSASEGTRVFGPDHDQKLAALRQSQIALAQAWAHSEADEAGHISGEGMLGEGELSANNLLKAATNTATSMSGGSGGGGKDDEASASGGFKGGGAGMDGSAATHSRDNVDRFGNRPLEEETQVDILLARKRREANDRYFQRVNRGVLDVVAKLEDVADAMRAVEQESMDIWGGDNDSEQQASFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ0</accession>
    <name>A0ABR3ZCQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15859">
        <property type="entry name" value="SNARE_SYN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="205"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="295" mass="32141" checksum="EF76F9BA256F480A" modified="2025-10-08" version="1">MSNPNALYLLADHIKLSLLERQRSKALNLLQDDDTDAAAAANAEAGSAAASERDTQDGHIARSLDQLEEGITSLKREQERLESEGEENKALNIGDALPGLQKKLDELTAQFNGKAPISSAGTSSSIKPRRSTPLSTAKKGVRFQDKPLPPPGTDGDDVDLEAQRNNLFNRPYTDDPDVDGSSSQEDSGAGRYGDHDNVQLHQMHSRIIADQDAQLDALGLSIGRQRELSMQIGDELDSHVAMLEEGERLTDQHQTRIDRARRQVGKIARSAGDCKQMVAIVVLIIILILLIAILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE05</accession>
    <name>A0ABR3ZE05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="12"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="339" mass="35850" checksum="D0F7053198F49C34" modified="2025-10-08" version="1">MKGIKITQYVKGPDELVVESLPDVQAAPDQYLIAVHAAAANFFDILQIQGKYQNQPPFPWIAGAEFAGVVLATPSASSVLKPRFAVGDRVFGASQGAYATKVVATEAQLQPVPPGWSFTEAAGLFVTAPTSYAALVLRAGVKQGDYVLVHAAAGGVGLAAVQIAKAFGAKVIATGGTEHKLSVAKAFGADHVINYKTDTNWPETVKKLTGGRGVDIVYDPVGMVDLSTKCTAWNGRILIVGFAAGKIEKVAMNKVLLKNISFVGIHWGAYSLKETEAIPAVWSGLRQLIDRGAFRPTVFTDGERFSGLDRVSATLKALGGRETWGKVVVAVPQEGESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF67</accession>
    <name>A0ABR3ZF67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="63"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="43846" checksum="D3BA7D652DB21CD7" modified="2025-10-08" version="1">MRLLTQSIARAAALRSCARRSTPSFAAAFNGARRFATAQSTADDAKAAASSSSSSSPASDSHVHIVEVGPRDGLQNEKRAIPLATKIELIERLAKTGLATIEAGSFVAPKWVPQMNNSAEILEHVLQHKISSPVPISYAFLVPNTKGLTNATAILQQHAEQFVADVAEAQFLAEKLGTNEVDGVETKPSSFLPAIELAVFAAATESFSQKNLNCDIATSLERFREVIREAKQITAAASAAAGTPIPLRVRAYISTVLGCPFEGPDTDPRRVAEIATDLLEMGADEIALGDTTGMGTAPRTKDLLRSITAAGIRNEDVSLHFHDTYGQALVNTAVGLEHGIRKYDSSVGGLGGCPYSPGATGNVATENMVYFLESLGMDTGVDLDAVADIGAWITGEIGKANDSSVGKAVLGARLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFT0</accession>
    <name>A0ABR3ZFT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002922</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF21">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="32"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="58385" checksum="E18BF1695295AFD5" modified="2025-10-08" version="1">MSLGATFVHHIVRNDAAKLDPPEIYNWRVFALAAAACFGGTLFGMDTGIIGGVLTMPDFKREFGLVELAKTNPTAAANLSANLVTVMQAGAFLGALLANPVGDRFGRKPGLIVVSIFAFIGGLLQAFSYGSFACFYVGRFVEGFGLGGATMLAPTYVSENSPRAIRGLLIGFYQLFETMGAMIAFFIDYGALLHIPGRGSWMVPLAMQSLPPVLIFGSILLCPESPRWLASKDNWEAATKVLSDVRHLPEAHPYVQQELLELRTQLEEERRSVHGTGFWAMQKECWLVPGNRKRALMAIGLMVCQQWTGTNAINYYAPVIFNNLGVGGTTQSLLATGVYGIVKMVSCAIFITFLADTLGRRWSFIWTGFFMSFCMFYLGFYVRFDPPVKGAAIPPAGYVALVMVYLFAAAFQFGWGPVCWIYVSEIPTNRLRGYTVSLAAATQWLFNLVVSRVSPVMLLHAGGPTGYGTYFIYASFCFAMAIVAFWVPETKGISLERMDELFGTADFSNIEDVGRAAKQVDVEASHFEAPAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG32</accession>
    <name>A0ABR3ZG32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_003174</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142:SF1">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner centromere protein ARK-binding" evidence="9">
        <location>
            <begin position="1488"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="69"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="270"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="437"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="753"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="798"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1433"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="608"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="798"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="831"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="848"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="897"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="966"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1046"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1090"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1125"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1137"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1157"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1259"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1433"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1455"/>
            <end position="1475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1595" mass="171678" checksum="2C5686087BA64F25" modified="2025-10-08" version="1">MAMRGPRHPIGAAPWIAEERTTALNIAQSEVEEFMFSAKNELDWLNEHMAEILSENQINVADIFKTPGKLRGKTPRTARKANKGDIRATKPLTDVFSSTPKGAPNPFAVSKLTSLQQQQRRQSPTFTVAEDKPAPPQKSQNPQRVVPVKVAAAGKAKTATAAASTQNIKKATTTAAAAPVAAKPTKAAPSLIDSGYHGSQSQDVVVDYNDDEEDELAGDDMLTQPFSQSMRPATPEAIVRKPVPTKAAAAAAAKQKAAVTATPAADLAMSPDVMADHPSPTQPTVEPTFHSAKEEQTAVVPSAAAPVEKPSSPSADTELLSSSPFCPVESPSSVRPTKIASPAKPQAIASPTRKPVPAPSSPLQSTTPACPPPRELLSAMGVSIPNAAVASPALAHMNVPPAVPTPPMASVPAFIAEKRAAIASSWQKEEEDVVVYEEEAHDEPMEEHGASEEGVLQPRKEEEREQDEENEETAARSPSDPSSPVRPMVRKSSMNFASLPARAPFTSNKSLGGAGAGLARADQARTSYYNRPTGGKSIGNVRMEDDDDQDDEMETDANNAANAEKDMAAHNKTYAQRLHDRISMLGKSQANAPRPSKSLAALAHQQETKSQPQKSLSPKRTATSVAAPGAFPEDEEEDDDNWIDPPANAVPASPTKTQAIVPTPTTEEVDPLDIQTEFVLPKQRQQDVSRPASPKRVQAPIIPERTTSTVTGHMKSASVPSLPVTESAALATTKPISVSNPTNAAHAVLAAVSEMQGRPPSPSKSPSRNYRDSPLKHVKNKLSSILKTSKGLLASSAALSAEGKSSLLSSPSSTRLGLLMGPSTESLAIKNRNDSASELTRPDLSRQTSANTTTSTTSSASVFPGNTDVLANQESPVRAEQSPVHSQSPTRPRKTRASTEREKREMKHREKELKEVQRMAEQMGKLEKMREKEREKARVFVEDQEKMAATVEKPAQIPAQRELRGQKQQPKSQPQPKQMVDEDDDMDELSQQPPPPKAKTQTSSPSRVAAKSTRTSPRKAKPQQDDDVDMADTPASMLPPPPPAHSTVSSNSSVPRSAQSTRTIRRPIKPTKDAPAKTKQAPTVIRVNTSSSQQHQQQSSQFHPSNSILAASLHDTLAGPPQLKNKASTASLHTKPSLQSLKSSVSSTGRPKALELAAKRKEAEEREAQRKRDAKAEIERKRAALQEQEEQRKQELQKQREREREQAAAEAAAAKKRQAAIEKAKQTRAPPPAHRTQLPSGPSTDYGRSDAQPPRPQSRLATATGTNMHRSQEEQHRPVNAVLSHTAKAMSKRPLPGTDAYESQNHGRPGTAGGNAGGSNMPAYQHKDAKRIRMSEEFDEDELEMGGVVRVSSIKGPPVRPSNGFKKDLPNKSVFGNGYSTAPTNVSRDLFKSTVTAQHNYQTKTAHPMDMAQVSKAAISFAPSGSNTTSAAAVAAAASQSTHKTPLRPAGPQPAGKSTAKSAGKSVGKSAAKSSPRFPNGDAIELPDIQTDDEDSEEEVVNAAPWADSPDLRRALMRQETVDPFQVFGPPGPLNMEEVFNKSKDRWHKFRARGSSANWSGIDRLTEDDIRKDMAARDKIRREGGWSYELGKQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGY4</accession>
    <name>A0ABR3ZGY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="745"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="809"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1120" mass="116988" checksum="453474ACA5321D65" modified="2025-10-08" version="1">MALDSSYAGSGSINNSNFPKTPKSPARSRFSKALPAPPPVLEKLLPSRSASRPSTSVDETPSLPPLPPASSAVLSTSNFSYIPTTATPTAVAPSSPSVPVSNTSAPLPPPPPKSSARTVPGTISSARSPSLSLFPHQPPPPPAKKPAPLPITGPAAAQPQPQIPAPAVPSRAIRRRPVGSSVSVASSDSNRSVQPSTSPPPQEPTPAAAPVLSSLSTLPQLPDLPSFNSFSSLSELPAAPVARSSLPDLPELPSAPVDADASSNSETQSQTKTVRAPSPPAAAQDASQEEQEQEQEQEPSSSRVASISSILSAYSEDSSALAGLSSSNSEVTISTNTSSVMAAATSSPLRPLPSEKGQVFLDVRQPGSASKLDEDVHTPLSYLLDGDYADEEDDATPPAVEEKVVVTNGITQSSSTNTSSTNYPNNSDEYDPYSDAYYSYKPPQPTVPKKNDTSTGNVISSVQVNEPESPVAPAPISKTEAVRPPRSTSLRHPPPDVMSKTVTTGAAGSGLGSGSGSGLKANDTLPPLPSLPQHSSTPSTEIWRRRSEKAETNLSVTELNLKATPALQNAIAVAVAADAKDKPDIPDTLHQNQKQQQQQQQHQLQKELPPVAPAKDGGYLAYRQPLPPPQSPLPPPPRSALNNQLQPPRSPLVGGTNANGVSPSSVAPSPRLGLPGRDIRPSRQASPAVTPTTAPQLQADAAPSMGSSLTKLENKVESTFKRKPAPVPSISTASPAPPAKELPQPTTTTPTTTTRSPLTSKPQPPPPPPSFQGPPTPEYHDEEDKAKDNSHGRQLKDGASIVPSTMGIVGTSSSSTTVVNVPVSPATSPAASPAASTSSAFASAQQQQQSPALNSGLVGREIRPVKSAARLAGQNQPQQPQQQQFAPRTSSRNVSISTIPGALNGPVPPSKQVPATVPEQQHADSAVSFVSETGSQVTIKPVAQKQLPSQGPQGGLPASNKEQNTVASPRPDSSSTDIDSLPLARGMPPLFPSGYMTDVITPDTVFAAPPPSKIQFNCLQRHHDMFRDRNVNYPLSCQTCQTFERSMRWRCKWCYLRICSGCRDVLHTHAKHDLSQLLTYLTEGGHDAEGAAGEGVQDVDGKANMQSLPSGAELPVIQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHJ6</accession>
    <name>A0ABR3ZHJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002434</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="266" mass="27710" checksum="011B281F8CE2BC66" modified="2025-10-08" version="1">MDKFSLKGKTAVLTGAARGLGLVFADVLASAGANIAVLDVGDPGSSLDEIATKHSVKTAFYRTDVTSRAEVAAAVASIEETFGRVDINVNAAGIVKDEPFLSTSDTNIASTFAVNFTGSFLVAQACAQAMARQKAKDPENFAGSIVFIGSVASHVPTVVQNISVYCASKSAVRGLVKPLAMELAPHGIRVNSLSPGPMQTDMYRQVAAAEPAFARQVEKETMFGRVGQPEELKGAMLFLCSGASSWVTGQDLLVDGGASSWNYPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHT8</accession>
    <name>A0ABR3ZHT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MRPL4</name>
        <name evidence="9" type="ORF">Sste5346_003011</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="288" mass="31950" checksum="A8B7E8D108E1CE4F" modified="2025-10-08" version="1">MAALGPSAARVRGAVSSWSSARNMMACSQSMHFASQQTQPLRPTQTPSSSFQSLGPSTLQSSSFSTSPVLEKRRPRYKPRDNNRLRGVSSIRRTGPREFLSVSDSPLPRSTLTVAPGGKEAKKAMADATRPETDPEHGLFQFFYDGQVAQPPTKDAAFGRPWTAEELRRKSWDDLHKLWWVCVKERNRIATAAVSRKHFDLGFGSHESGERDNAVRETMGRIKHVLTERFYVWEDAVELAKTDPEIDLSGNGPAFRPTAYLEDEPIAAALEGEAAPAENRSEQPVPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIK4</accession>
    <name>A0ABR3ZIK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="100" mass="10980" checksum="2A94ED510E4AB444" modified="2025-10-08" version="1">MSSVDGAIPLGTFVSVGLGQPAKWLIFETPALSTTARTTMMVAGAALLAIGASSDLFIKAALALRRVDWRRVGKHVIHLSECSRWFFTVVSISREVYKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA2</accession>
    <name>A0ABR3ZJA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor cwc26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CWC26</name>
        <name evidence="3" type="ORF">Sste5346_002206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018609">
        <property type="entry name" value="Bud13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051112">
        <property type="entry name" value="CWC26_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809:SF0">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09736">
        <property type="entry name" value="Bud13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="100"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="373" mass="40822" checksum="0851CF769F069C8C" modified="2025-10-08" version="1">MPADLTSYLAERYLVADTKPTTKKRKRKHNKDGGGGDGLLITDDDDSGWTKGGGNKDDDDDDEVIGAGGGYGAGGTIAGTSAEFRKTKKSNWTVLGNAGAETSSTSTPAPETDADAIIAAAAADTAAALAAEDEAPVVEAESGSSSKKPALMSDGTHAGLQSAASVTAQLERRRREEREQYERERKEKRERRRKRGEDEESGEEEVVYRDATGRRVDVALRRQEVRQAALEAEQKERDAKDALRGDVQREQARQRREELADAALMPLARGADDEEMNRELKAQARWNDPMAAFLSKETPITASSAGKTVSKAGSAKSSRPVYRGPAAPNRYGIRPGYRWDGVDRGIGFEAERFKAINRRERNKDLDYQWQMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA6</accession>
    <name>A0ABR3ZJA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="286" mass="30541" checksum="24DEAC4D41F63F24" modified="2025-10-08" version="1">MSSFALPCGRRMAYALSQPTTTKPVVLLSNSLCEDYTSWGRVVPVIENLGFRTLRYDQPGHGQSPAPAAEDIKKTTFESLADDVAQLLKHLDISCLHAWVGVSMGGIKGIYFAARHPGIIQKLVVADAIAASPTVAGAPMDVFANRVAAAKTAGNMTTDLDNVGKRWFGEAWLAANPDEAKRMRASMDTTTLEGLEACCAALSSPTFDLRPLYPSVGKGADEALIIAGEKDADLPVKMQDMRAAVEESLVANGKTTPVALSIVPNAGHVPYVDGFDQFCQILTKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKZ7</accession>
    <name>A0ABR3ZKZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF18">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="62"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="559" mass="61150" checksum="37BC5548DC8BCF33" modified="2025-10-08" version="1">MASERAVPYRAYGKDPALVESGAYDHNDDYSPNGNSVLNDGDDGLVTTAEDRDLKRGLHQRHLSMLGIAGAIGTGLFLGLGGAVQEAGPLGALLGYLTVGLVVCAVQFALGETAALYPVTGSFVRHAEVLLDPAWGFAVGWNLVYGNLLSIPTEITAICVLFQFWTDVTPAVWIVVFIILTNIVGFARIRVFGEVEFFFAFLKILLVVFLIILGLVVDLGGVPGTPRIGFYYWKNPGPFVEYIASGAWGNFLGYWSVMTGAVFSFAGVESLAMAAAETRSPQRAIPRACKRVFARIAVFYVLAVLIVGMLVASDDPRLDDESGTAAQSPFVIAASAAGLPAIPSVVNAVVITSAWSSSNQALLSGTRVLYGLALQKQAPRIFLRTTSWGTPYVAVGLFTLFMFLSFMTLSDSALNVFWWLVDLTAAGVLVSWITILINHIRLRNAFHVQGIPPQSLPWYNSWTVVSSWFGLVMCVLILLTGGFTVFTKGNWDPATFVSAYLDIPLVLVAFVFWKVYKRTNIVKLKDVPLTEALEQVAYYEEEPETKYSKWLVWISWIWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL48</accession>
    <name>A0ABR3ZL48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Plasma membrane ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="21960" checksum="545298FC58915078" modified="2025-10-08" version="1">MVLMGWGGAEGFSPVVGIFFFVGPVLLVFSMVFEWIMGNFFPMMVMGLFAVFWLSFGVLQLPTLQLGAAYVTSADATGTTSPAYNAVIALYLIVWGFALFTFFIFTTMINAVFSAIFLLVSVACWVLSGAYWKVSNGDYTTAGHLQKAGGALLFVVAALGWYMTFLIMAGEMRMKIKLPVGDLSHFWPSTDVDLAAQDKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMG1</accession>
    <name>A0ABR3ZMG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001598</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF413">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="425"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="600" mass="66393" checksum="0B20BD149A71ACCB" modified="2025-10-08" version="1">MSSCCPRLDCRLTFPRLLFSDPIYEGVDTVPSTILRNLTAVSGDIAYSDHVTDNLTVLLSKYTETQNGLLQGLLYVPDLALNDPCTISERDYVPDSAVRQGNLPATNYNLIALAPWYSVACTKSYLSSARYDPLRAFIFYQPTNDTTKPPGPDSDVWDLQDNGAWKLDNHYPIFAVSGALGQEMMYQLSLYSGNLTDVPFGENISQLYNPDPDDYVRIWTELTVSTPTGLPNVWVFILAVIGVLLAVITLTSLSMHFMWRRRRASLQRRVAIGEINLEAMGIKRLTVPASHIQKFPLFTYNYDPPPPQPRSPPPPSISQSPPASPTTEAASTVPPLSSTPPSAVLASRRLSRRSSTRPHQSLDAALDAALDNEIFANSNSTSDTRSQSASDHSVPAVPSAVPASPVAETIPESPVMGDLEFQPMCQICLEPYQNRVTIIRELSCGHIFHPECIDEFLAHVSSLCPLCKTSMLPRGYCPQITNAMVRRERAIRRLRERVTVDDGLPGGSVGDRGRIHSWSSSIKKHLHSATDRLSMPPSFGTITQDRESGIELKNQPILRTHSIPQLPAMNTSEATRRRMARLAGIQLRDLQPEKDETCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMV1</accession>
    <name>A0ABR3ZMV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rfc1</name>
        <name evidence="11" type="ORF">Sste5346_001796</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="359"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="498"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1034"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="259"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1040"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1074"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1108"/>
            <end position="1121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1121" mass="121297" checksum="70399DE76EBEB556" modified="2025-10-08" version="1">MPDIRSFFGPKGGAAPAKPAAPKKEEAPKGRGRARKVVEESDDDDVGEVKKPSKSTPKKKKGDSQPEGVEISASDYFSSSKTNQKPKTQTTPAKAAPKSLPKTEIEIRVSPRKKENVAPAAAAAAAELPAKKKRSTAAYKSYDLDDDEDAYKDDEDGGDDIFAADIKRGKRKNDDYVDDDDESEDDFAPKPKRVASRGAKAAAITIDSDEDDFEPAPKKDKTATPKKSNGAAGGKKRKNPDSESDVDLSPVSKPRKKAATTAATTAASKPKAAAAASTPKKAAAPKAAAPKATPKAVPSSSSGGNSSVQAILDSIPLITPPSPPPKDAKAAKFNWRKAAAGGGNTGAPPNAGAVEMPEGEPNCLAGQTFVFTGLLKTISRDEGQALVKRYGGKVMGAPSKNTGWIVLGDDAGPSKLAKIQQFGIRTIDETGLFEMVKRLPAGGGDSKEAEKAREKQDKELEKIRIAAEEMNREEESKRLAAERAEKAAAKAAAAAAAKAPATNGKGGSSVQAAARPPPVARPPLPASSQQLWTTKYAPTQMNHICGNKAQVERIASWLKNWPKAKKYDFKVKGADGLGNSRAIIISGPPGIGKTTAAHLAAKLADHDIIENNASDTRSKKMVENGIGDTMDNTSLMGFFAADGKKVSAEKKNIVLIMDEVDGMSAGDRGGIAALAKFCRKTEVPLILICNERRLPKMRPFDNVAFDIRFNRPTVDQIRSRIMTICLREGLKMPTQVVDALIEGTGKDIRQIINMLSTAKLDQSTMSYDEGKAMTKAWEKHIVLKPWDICQKMLGGGLFAPASKATLNDKIELYFNDHEFSYLMIQENYLNTRPQALANSTSRSKREANLKYLELVDQAAESISDGDLVDRMIHGPQQQWSLMPTHAVFSSVRPASFIAGQLTHSGFTSWLGNNSKTGKFGRLLREIHSHMRLRASGDHNEVRQQYLPVLWYQLIKQLENEGKDAIDDVIELMDQYYLTREDVDAIRELGLGYMSEDKVNIDTQTKAAFTRKYNGMAHPVPFMKATNNVTVAKKSARDAPDLEEAIEEEDDADVVAEPVDEEDEELDLKKDKYIMKPKAKPKRAAPKKKAAAAKDDFLDDDDEDDAPKARGKGKKTGGRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMX6</accession>
    <name>A0ABR3ZMX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gem-associated protein 5 TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_001830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034605">
        <property type="entry name" value="PGC-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528:SF11">
        <property type="entry name" value="FI18188P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15528">
        <property type="entry name" value="PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="8">
        <location>
            <begin position="562"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="828"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="920"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="976"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1155"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1417"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1691"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="980"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1002"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1070"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1171"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1209"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1243"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1269"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1498"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1545"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1699"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1717"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1732"/>
            <end position="1751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1810"/>
            <end position="1819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1820"/>
            <end position="1829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1863" mass="201560" checksum="2780BEDC022A9D4F" modified="2025-10-08" version="1">MMRHFDPCVATADMFLYAQGNSIVCCHHDTLTIERRFSRHPDEVLLLAVDNQSERGAGRLVVSYDASQNAIVWDIMSGNEIARFASFSNLTAVAWMRNGAVAFGNDSGTIILFEPETSEHVSFRTIDQIAVTALAPATDCRTFAIGYQNGSILICNLQPRFTILHNLTTSRGPSPIVGLSWHASSTRQRSDMLAVQTYDGDLRVWSVAKSHNGVEPAKVVRILKRTDNYFPGPNWMNWSKNGRIIQFSEGETLSWDVRTKHVTYDSIPTLEHVRGLAVYGPGASLFTLGANNTVQQFDLNAPAVLVADVQHPANLLPPSPPVSVEEQEKQEAAAAAAAAAASSAIETDSSVATTSESEISIHLDGGVSESDDDYQSPLARLVNAGHIVDDTESDIARTVSATSSAVSHISEDKSETSSKTPGQYAGSVRSRGMTEYTYMSIGSSLKSSIHPNNMYQQPQHHQQQQQQQHSHRKTPNPQRQSVATYSTATSTTFSTTSSRTGMSRPSRLRNEVPRSPDDAKVLDLFKFTRSRLSDVPYRMPPAPANGARLTNDDLRRQMLYTIFGWTEDIGDLVRDEMDRYPAGSANRILLAKWLGDIDPDIMKASSETMTSSDWMLLALSGIGSQASQHKLGRAYTQRLLESGDVHAAATIMIGMGDCNDAIEIYASHHKYMEALIVAALFYPSVWERQSHLIKKWGEWAIKNGRRELAIRCAACTGKESSEPWTSPSAAQINFPSINSALPELNSPPLSPPSLMQRGPQRSIAKSSALRLITNFSDATSNTRAQIFASDADGATPIAAGVTPIVESAISPGHNDATTAFLRPSQRSVFNTPSSARPAGGGFGRQRLPSIGEGPQGSQDANHPRNILKGVSDALGLQSQPAEGIDAVAAQAPAPAPAPVPQMTQVDNGHNLSIGMALQRASTSSPLYRRKEQPPPSPSPASLAMLMDGRHSRNGPRNRIPVGVDLQLAPVAPETIMDMTSPEQTGASSNRYRWPSRRRGPASVSSSVTSNSSVGHSLRSSRFRTGDAPNTSKTLDEYINSLEVVNAKAARSSSKDRHQRSRDIGRQRRPSVATPSTSSVSTVTSHSREASSNTDVREWVQTRSRAGSKTGGKRSPRSPVPMSPEDLISLASTPRMFARDVPAVDNDDMASLTAKKTISTSSAAPPPVSMQPLRPSSKSRPTSRASSRGRSTRNRSPDRQPLTLDIPRGRNSSRTASAIRSPSSPLPFSNNAAQYRDSDDEEDYQRAVEAQEKFRNRDRTSQRGRSSSQGRRDASPGSVRARERSRSRRRPTPDVTSTAAPAATSRKERALAGPPPAPSAMAVAAGGFDRYPASQQSLGEELGRRRTQSAMTNRGDLRQLSKDERAQRKAAAARELEERRKSLVRHPNAPPIMHPDYLSPGLNQSFGQISEAPELSSDVYSRHPNDLPMRSQSTDPVAMQSSSSTRTRSMFAPRGHQSIGLPATPKAMRLVLEPGAGAGSSTPPSVPPIPAAYGHQRTSSGSAGGRSSPETKPSPKRNAEPAPAPLTLSATTYSLRSEVPPAPKTSVPTKSSEPTLTLLPSTVYQPPSMSRAAIPRSMSAPPQELVYNKDFSASRKASREKNPTIPESSNDDNDLAGTLSPTIYRRPSLDNMIPPPPPPLPAPPMLKELAHLAVPPPPPPAPLPFGSSMNKPVVYGGHTTGTIEVVMDDGEVQPVVTISPQNTGNNGNNGNAPQYANYPPPPPPPPAPPIAQENLSQSRNGHQRGRSSTDNSIAGRISRATERMRSASRGPNAASRTKSPEITMVPYESIQIPQSQSMGYAPYESVPPPQSSFASCNSPPQQTQMQFQPQQQLTQQQLAQQQLQLQQIEYQNQMRTGLHQSEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN55</accession>
    <name>A0ABR3ZN55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SIT4_1</name>
        <name evidence="8" type="ORF">Sste5346_001995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="224"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="422" mass="46239" checksum="4463A473C3A86782" modified="2025-10-08" version="1">MADVPRPGPAKLTPGAGLDEWLEEAKQCHYLPEAVMKQLCEMVKEVLMEESNIQPVSTPVTICGDIHGQFYDLLELFRVAGGMPGETDVQAPRTMTAVITSEDIEPPTEIRNPRLRRKLRPGMIGGGDDAAFDDDGEGSSGGEGEGATPAAAGDAAGDAANGDADNADNSHTGNTTEGASSTSQSADTRFVFLGDFVDRGYFSLETFTLLMCLKAKYPDRIVLVRGNHESRQITQVYGFYEECQQKYGNASVWKACCQVFDFLVLAAIVDGTVLCVHGGLSPEIRTIDQIRVVARAQEIPHEGAFCDLVWSDPEDIEAWAVSPRGAGWLFGDKVAHEFNHVNGLKTIARAHQLVNEGYKFHFPEKSVVTVWSAPNYCYRCGNVASIMTVDNNLESKFRIFSAVPDEFRHTPFNRRGPSDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNV3</accession>
    <name>A0ABR3ZNV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS15</name>
        <name evidence="5" type="ORF">Sste5346_001632</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="153" mass="17538" checksum="2C94237B26C4A9D8" modified="2025-10-08" version="1">MADSEYNAEEAAELKRKRAFRKFSYRGVDLEQLLDLGSDELRDVVHARARRRINRGLKRKPMGLIKKLRKAKQEAKPNEKPDVVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYRPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNW5</accession>
    <name>A0ABR3ZNW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="69502" checksum="4D53839508467F92" modified="2025-10-08" version="1">MVQRRLEFYSQQPPQARQDEAARRTPSVSFLDLPYNVRHRIYTLVDLVRFCPININQEGLRAEALRTGAKKRTGYSCFYTARRFLGRDFGNETVPSCECPALPVALLYVSRSISDEVCHILYSENAFTISRSDLWGLSPLRNMGKRNAASLRRLTIRLNNSQCTFDFKIEAAFDMPPCHPLCQSHGIHDALLSNQTRQGGVVIQEWQDLCRTWGVHLEPGQLRLDFVCDTKDRATAEQISNTLTMLPQLQECSVRLGCKPHWDTRMLSLRTTRRLQEAPFKCSNDRSIGKRAYSYYLPTEILTRILEYSDLIAPYDLEWRPDGGFAPYDCCKSCTSTLDCCTCSKYYATHSTTCKCWLPPTALFLVNRQVHDAAMTIFYGRNRFVALPPGGRMNGNGYFISKTRKLLKDSEDPPLAQFLARIPQRAHALIRYLILVMPSTVPWYRRPAVEEDGGRVWVITKELVKQRLDLQQLQLSMYSETIFYIHSDDLSPCWADYAVAYSRMLGDLSVWRGLRDFFLYLQYPHPYRVRSFDKVAIPFEKALMGDDYNSIERGKWDEPLRLWYNGQSREGTVYGPNGTRVWPFFDEDPERSPPPPLAFEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP23</accession>
    <name>A0ABR3ZP23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF40">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="119"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="838"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="720"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="755"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1218"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1325" mass="142535" checksum="7F8AA75FA97ACCDD" modified="2025-10-08" version="1">MLWATWTNTPLVSSLVLCSLVLLIWAVDPQIIQLNVLFLFASLALLFSLAPERTAAVFEALPGIATALINDYHLGGLFFTNARMLFTGAAAVWLLRRGLQTLWKPVPELIDILGVDVPAPPDVSLTAIGVDKATITWTRPPSNRAVDKYVIQVNGVNVGESATSHDTFITVSGLKPNHFYNVRIIAVGSNNFQAGSRVLRLRTFGSDGRPRLGTSRLPSDFTEDDAASASKQHEASTADENGSVKHFVTSTFGVAQPLPSELPQSLSREGTSLSSLTPSSRRNTVNRRHSPSTTSLDQQQQFNGAAAAPSADEEAGVTEAQMAELNQRYLALRKETEEATAACAKEEEDMKKTIDELEAEKQAKRKEQKRKEEQTEKLKREQGATERAMRNAISRRAQKEKRLKEKTAEFERIHNSIEEWEKSIQEMREKQEDYSRQRTELDEEYQQKGNELRDSNKSVQTECSNLETELKEKRRLVKELEDARTTLESNGDDTGMRTEIMALKRKQQRMENEYRNRLNHENRRREGLDAHILVLSAQMQQIPQPNYAMYNPAASPPIMSNIMSPPNMPTTMGYDYDPSAVGHLEPDNNPMSNGAVSTPAPAFAHADLNGLPPSSTPPFVSSGRPPTQSGGFLTGPFMGSSADHPGPEDADAGFKALTMGAPLSPSATSLLPSNIFADDEPPSPSLNFRTMSPFIPMDAESPDILGSLNNFTNNHKTADSSSSHGSQDNSTGNNSNPLNINGLASTDSPKTFPESIAAGAASGPQSPASSHRSKSIFSSPHASSQNLPFSSYGIDSADGRPPTTSALPSPIADPATVSGQPASSTRFNLFSFQRSRAAKAAGDEGPALGTLKHGQSQSFPRQGEDDEGNKNRRISLSAWSMFNRNSAGPEIIESQFGSSGQPINKTGGFSARNLFPFGARGGNIFADRDTSSPRPASMASIDMPRPSTDSGSIWGPPVDNGAGGSGLGKSSRLWPSDNAWPSRNPSRRPSIHGSPSALKTNLASADDEILDEEELLNPETSPSQVGVIGSRPPASAPKVNKTLNPAAPTFMANIFRPKADKDKDHKDKPKGKGKDKSKKDRSASKEHHESLETGAGTSVPSLMVEDSPSISRMSRDGLSVHTQTSVSESRNSLDYVVSNTTSEPNSLGMLSSSKDSSENALLKLFKKDSTGKLSFPRRIGRAKGPGSMASSDKNASISEQRSSFGDFDDLAADESVLSTSSSRRTGMSMPLATASTVSTSGGGADSVTSSPSLGPSKSSRDGNGKSEGGKLKGTGWFSIKKKNREKESLDIDRSLHGLGLGEPDSTVSSLATTTSNVTDESDRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP34</accession>
    <name>A0ABR3ZP34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VMA13</name>
        <name evidence="7" type="ORF">Sste5346_001559</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="382"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="503" mass="54865" checksum="4DA5F7CDB2A3E38B" modified="2025-10-08" version="1">MSAEAPTYLTALQNNIRTRPIPWDGAVRAGTVLEWQLTKIRAVDKVKKDVRKQAVESDLDGYRILFAGGANDGQPSVLQSAARRTDVVQYILVLLNDLLEAIPSLAKAILATAKKEDPYRNILPLLAHSNNADDPIPLLTATVLTTLLSNARDESKATLERALPALLSYLSTLAQQSTDAGLQDIGVLESSSLLYGRATRKQFWAQRSETVAPLIKILRTAAGVSTSGGEDTAAGLWRATGNGHNGSSASGGDAVTSRIGALLEGSIGGGVGLQLLYHVLLVLWQLSFDAADIGDDLNEEYDFVLLATQLLRLSPKEKTTRLLVATLLNLLSNNRATLLPTAVLARLPALLKNVAGRQHADPDLQDDLQQLRDLLDEYTATKTTFDEYVAEVNTGHLRWSPPHRSTVFWAENARRILDEDNGAIPRKLAEIMAKPWDNDKAVLAIACNDIGALVREVPEKRSTLEKLGLKTRVMQLMGEADEAVRWESLQALGGWLKYSFETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQY9</accession>
    <name>A0ABR3ZQY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044974671" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="544"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="564"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="617" mass="66379" checksum="8EA897ADFE66F67C" modified="2025-10-08" version="1">MRWANNRIWQPLLLTAAVTSVASAGRSLRHVGKSDDVFAAFAERSSSLYDNIFAEAEDPVEKRAPTAKFLNNNTSSFSVNGTGIPDVDFDIGESYAGSLPLSSDPNDENQLFFWFFPSENPAASEEIVIWLNGGPGCSSLEGIVEENGPFIWQSGTYLPVKNDWSWNKLSNIVYIEQPVGTGFSVGEVTATSEEDVAEQFLGFWKNFVTLFSLEGYKVYVTGESYAGMYCPYIASAMVDANDTTYYNVSGVLIYDPVIGQNDIQDNIPAVAFVDYWAGLHPFNDSFVAEIHQRDAECGYTDYLNKYLVYPPAGQQPTVIAGQEANGTTKPDCAALYYDIVFAALTVNPCWDIYQVATTCPLLWDVLGFPGTIQYTPVGANIYFEREDVKKAIHAPLNVNWSECATHNVFVDGNDKSVPSSFHALPNVIDHTKNVVIGHGSLDYVLIANGTLLTIQNMTWGGELGFQSPPTEPMFVPFHDDISLSSVAGSGVMGTVHSERGLTYAGVALSGHMVPEYAPSVAYRHLEFLLGRIPSLSSTEAFTTNTNVTQPTGSIGNGNAPQGYSTVNNSTTSSASGGSSSNSNATGGTTSSAPGPGLSLSAWASLFVLPAGIAALLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR50</accession>
    <name>A0ABR3ZR50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle pole body-associated protein cut12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021589">
        <property type="entry name" value="Cut12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11500">
        <property type="entry name" value="Cut12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle pole body-associated protein cut12" evidence="3">
        <location>
            <begin position="153"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="258"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="667" mass="73767" checksum="72503BA848206DDB" modified="2025-10-08" version="1">MLGWAIKRGLNGGRDAPDDEDDTRIEQPDTPGPVFAARALKSALFGTPARQDETEIDIQPAVAPIPTIQEPAPSTSSAATSVKSNTIAKDTGVTPGRLPGILLTPGTATTRRKRVSFGHEVPGEGVEKKNEFRIDRNGRKPNLFGDHMRSKVSRTTLGTALENARKQSNKAAAPSKEAVDNAPAPNTNNKPAVDEFEDDPWEEVGDDDGPDPDITVDLNEPHSQSGRYWKSEFQRYQEDAKVEMGKLLKYKQLAKSYAKMKDAEAADMRTKLQEEKEKVTEMEGRITELAGQIARKRMDGSDREYQELISDLTRQTARAVQYRNQVKELEAMLQDNEKPAAAALSTLATATSPRTQRTLIDTQRELRRARDQAKELTQAKEEIRRLKSALRAAEKQVTLKTDGSNSESKTLAADLAASKANAESLAAKADDLEKRAQFAEDERRQKDKELRLLQRKYDSLKDDAKTRVGEAEQVMRRKNEEIADLKKQVREATVAAVRHSAQEHVDDVKEVKEIKPIRISKATDAPVSDSAAAKLALLRRRRGAEPLRPISDAVQRPKVLESIGTNHIHAEKEKEKPKVEPLTERRTKVAPTKPYRATISVPATRAPAPAAEHDDPVAAAAAAAADASCLSMTSERAAAAIARIEKRRAQRKLDLEMMRNKENMQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSK5</accession>
    <name>A0ABR3ZSK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF267">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="37"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="343" mass="37003" checksum="659B05A04315C7C5" modified="2025-10-08" version="1">MTSSRPTSVAVLAAANRPTLKDILANSAPPPWTLGAFMAYLSQNHCLETLEFTMEAERYQTTFSQVQLDEGQDGAAQWSQDAQDYTFAIWRRLIGTYITPLGPREVNLPGPVRDRLLALDKSPFPPKPSELNEAVTIVYDLMNDSVLLSFVDSVNTAAHQEQHTTSDADDHHHDGRQGRPRMRMPKDSSSGSDESSRSPKPSFLPQLNLRRNEGRGRSPSSSSVDASSAERVGLVDDNGSSTPPAGEPLTPPTTPPTSDWNFSTSPNGLQRAITVHNAGWKRMSAKLGLGSLNRMSRSSRRPNNTSSGSNHSASACDASSSASTDGDASSGMDIDSQQPGHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTE2</accession>
    <name>A0ABR3ZTE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF39">
        <property type="entry name" value="AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="4">
        <location>
            <begin position="70"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="323" mass="34997" checksum="8120B6B21254B6CD" modified="2025-10-08" version="1">MHLEQPFAPSRRGVGNIKPNPMLDLDRELAKYPPYDAEHNPDGVLDISSSLNLLMRDEAASFVTDHVHVDPAKVLEYGETAGSAALTGAVARFLNRHFRPSSPVDAAHIMAANGVTALLDIVSFAVCDDGEAILVATPMYGMFMSNLQTRNNIAVMEVPLHDVEGEGTNPNTDTFDGRNAAMVVDRFAAALMAARSRKLAVRGLLLCNPCNPMGRAYPRRTLVALAQFCHRNDLHLISDEIYAMSIHPPVTVSSQLLSPSTAPVMAPFTSVLSVVDEAGVDGRNIHVLYGASKDWGLGGLRLGFLVSQHPTLWEACRRLGPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFW1</accession>
    <name>A0ABR3YFW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_010371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000137">
        <property type="protein sequence ID" value="KAL1887196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF12">
        <property type="entry name" value="TRANSLATION INITIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="116" mass="12537" checksum="30A5099D0DD4B8D8" modified="2025-10-08" version="1">MSRELISSEKFPSKPHNNPACRVPGLIFCAGQTATGEIKQATRTALQNLTEVLELSGSSVEKIVKINVYLASMEDFAAMNEAYINFLPQPMPPRSCLQALAPGKGTVIEIECIAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHD8</accession>
    <name>A0ABR3YHD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">nicotinamidase</fullName>
            <ecNumber evidence="6">3.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Nicotinamide deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PNC1</name>
        <name evidence="9" type="ORF">Sste5346_009993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; nicotinate biosynthesis; nicotinate from nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000109">
        <property type="protein sequence ID" value="KAL1887755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01011">
        <property type="entry name" value="nicotinamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="8">
        <location>
            <begin position="8"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="228" mass="25058" checksum="7F56123FB4CC881E" modified="2025-10-08" version="1">MADKFSPALIVVDLQEDFCPPNGSLAVPEGRETVAVVNQMLALPRFVLRIATKDWHPQDHISFASNHPGKQPFVDFATVTNPLNPDEPSYRTRLWPDHCVQNTPGAELVPDLQVKGLDKIIEKGTNKDVEMYSAFYDPFTNPRVSDSGLVGLLKEHKVTHVYVVGLAADYCVRCTALDALSEGFETYIVEEGTRAVDAGAWPTEREQLVAAGVHIVHLGGPEVARLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHS4</accession>
    <name>A0ABR3YHS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Maleylacetate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010263</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000124">
        <property type="protein sequence ID" value="KAL1887383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08177">
        <property type="entry name" value="MAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034786">
        <property type="entry name" value="MAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF105">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="174"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="38515" checksum="D622F766AA5743AF" modified="2025-10-08" version="1">MLDFTYKANPATVLFGSGTIRKVPGELARLKLSKPLILCTPQQTAQANDLRTILNSADAADGQRIAVAGFFDQATMHTPVAVTEQAIAVTKDLACDCVVSIGGGSTIGLGKALSVRTGLYHMCIPTTYAGSEMTPILGETQDGRKTTRSDPTILPDSVIYDVDLTMTLPASLSATSGVNAIAHAVEALYARNGNPIINLIAVEGVRALAEALPAIVQDPSAAEPRAKALYGAWLCGTCLGSVGMSLHHKLCHTLGGSFGLSHAETHTVVLPHAVAYNAAKIPEALGLLAQALPDSDGDAIRGLNVLLRKLGVTRDLKTLGLKGEDVSKAADIAVSNPYWNPRDIERAPIEELIRRAWVGEDARADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ02</accession>
    <name>A0ABR3YJ02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_009744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000099">
        <property type="protein sequence ID" value="KAL1888134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="29"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="563" mass="62647" checksum="E08BC1298626C3D5" modified="2025-10-08" version="1">MSSTSANGAVNGVANGTNGTNGTAAQEVDVLIIGAGFGGCYSLYRLRQQGFKTHLFEAGSYLGGVWQNNTYPGARVDSEIPYYQYSMPEVWRKWNFSERFPSGQELKAYFKHVDETLDLSKDISFNATVADVQYDSTTAKWTVKTESGATAVCRFLICATGSSFKPHFPAFKNLDKYKGELIHSTRWPNDADASITKGKRVAIIGSGATAVQCTQEIAKQAQHLTVYVRTASISLPMFQRPLSEFEQRVNKSIYSGLLARCRATKSGLGYDPRPGSTWDLIDAEREELWEELWARGGFNFNQANHRDFLVDKKAGEMMYAFWAKKTRPRVKNPAKAAFLVPEKPPFAFGTKRSSLEQDYYECIDQDNVDVVDLKANAIQEFSEGGIITADGNERPFDIVVMATGFDAMTGSLTNMNIKGNDGVTFEERWKDGVFTHLGMCSSGCPNLFMVYGPQAPTAFTNGPVFIEVQVDIIVDFLKKLRSENIVSIEAQRPAEEKWKQAIQDANDKTLLPLTDSWYMGANVPGKKREQLNYLGGIQQYEVECRTALETLEGFTIVRGEASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJL7</accession>
    <name>A0ABR3YJL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine-protein phosphatase non-receptor type 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000097">
        <property type="protein sequence ID" value="KAL1888230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="58184" checksum="4500E30A6908A3A2" modified="2025-10-08" version="1">MRLDTTTSTSPTVTTVTSGSAVAAPAAESGGDSQPYIAGDEVSPTFAAQNIFSVKDGSDLGAIRRPSRRRTGPLSASQREKAALIRKLGACIDCRRRRVAEYSPLAGRPISPARSGRVSFGQSDAQDMEIDTTPTPTTPHRMADQQQHTQHQPPHSRTPLQSQAKPHPVSLPPPISRRLSVGNESRLRTPLPSGPSVRNLEKLASAALPGIESLSGDLQNAAARIINSTNPNRTRYEAVQVMILVWSNDTDHEVVDAIDDLAELFEKKYNYSVDLKAIPVGAQSPYRWLLHTASQFINNRESRDTLKIVYYVGHSYLDAEREMVLSSSMDKSAAQDTTIRWSGIQQLLEDATSDTLMIMDAAFYPCSKMARRDGVFEVIAASAGEDPKRALGRVAFTRALIDELSTRLSQKFRGLMSAFSAAELHVKLMSNYPRIIEDHNPDKERLTSFPAPLHIQIASDARLPSILLAPCRKTLPASPEASAPGTQLNLTLRLVDGTVDKPGWIEWMRLLPEGVREVKCETPYRNNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKC4</accession>
    <name>A0ABR3YKC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000089">
        <property type="protein sequence ID" value="KAL1888599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="50758" checksum="EEA3CFBB399CF69C" modified="2025-10-08" version="1">MATGPLRFDPDCDHSFDDYITPLDEAAAENSLAPLHAVQRKRIRGDDNDQDVSACEPAQKKTKIDRQTRHSNEDRRAPNEDVKFDFSLFVHCTPSKDSVAETARDGQLADTTHQDGTDFKPDPVARVSTPPPYHTPDLQRTTVSPKDLQVVADQSVQIVQLAEPFSQPGIVHPISQSISQWHGHGNQFGEGYDGFPVSGLHPFDQPASAPDLMGPNIMYSYPSPLLANEPITRAGYSHHPAHTSYRAPEPNMGDGQQAARRSSSSTSTSGITNSNPGPRPTSAGSRQRPRRTRSTASSSRGRYASEEEIEARRQRDVFFMYLKDEVGLTYKEIKSQHNFTEAESTLRGRHRALTKASDERRRKPKWSDKDITTLRRLVGEKLATQVGAPSFEKISWKGMQEEMRSAGCYAFGFAALKKKAKELLGSSTDDETDIEAAEVDEGHTGNPANVGSNASNPFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLM7</accession>
    <name>A0ABR3YLM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dihydrodipicolinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DAP1</name>
        <name evidence="9" type="ORF">Sste5346_009009</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF72">
        <property type="entry name" value="NEUDESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="64"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="179" mass="19940" checksum="5A8C7316D1701CF1" modified="2025-10-08" version="1">MDYVEQRMAQEAQRADMASAVTTLVTPLNVLLTAIVLYTLYSIFRPTPAPAFPKDPPATVFRTYTPHTLLPFDGQDGKPVFLAVRGRVFDVSSGRNFYGPGGPYENFAGRDASRGLALHSFDEAMLTKDLDGPLDPLEDMTPEMLDAIQGWEERFDSKYLVVGRLVSVADYEKEKKEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA6</accession>
    <name>A0ABR3YMA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF6">
        <property type="entry name" value="BZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="65416" checksum="FD3A16BFC4956D32" modified="2025-10-08" version="1">MSTATGSVTMTSTRPEADAAERKRLRDRVAQQNLRNKRNRHIESLEKQVKLCQELHRFRDDHSNQTDQDNLKTIRDLRAENAALRERQKQLQALFQSFKDVFEPPAEVIAVATTTLADAVTVSQVPDVPEVPTAQETDNSKTLRPIQPSQSLQTNETSADERNPISTPPPPPVQHTAPSPVSSTSTTEVVVSTSVPPYYNYNKTVQDMEGLPDYSTWLAGINATGSSTDGESESDALNHQSHNQNHNLQMDDGNMSGISNQHTGYAMHPPGVPLQATATSLFDTNGQFSATSGVTDMWSNRIPAPMPTSLQATEADLAANYNSTIVAYYPFMYSAKAPAAEETETAAPDNSGLALWAPSGTATSMAGAGTGVEIPVWARIPVRTSGPNDVRRSAWDANMRIIFDSPEVPAPLDIMFGSHQNPLASSLQRSIKTYYHGHPERLAVGWLTYHYIKWRTNPTAERYALLPQFLKPIYEQIWVPHPGSIDLIFWEGLRLKMLKNFDRYDMVKFIRTYTRCLRLRWRWDEDVLVTDALGKHVLRPDYIERFMSAAGWGLKPEFVTYYPELFDGDEWDQIVYNPGPKHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMK9</accession>
    <name>A0ABR3YMK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">O-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="24797" checksum="5573DD1EE73B4A68" modified="2025-10-08" version="1">MSNTAIRDEPKHIRSLLTRLHAESKAQEAALTRADYDNKTSIHDLMRDKFIALDEDKAHYIYQLLRATGATTIVEAGTSFGVSTIYLAMAANSNSKTNGKTPLVVATEHEPTKAARAREHWQQCGEDVVKAIDLRVGDLRETLKTDLENVDFLLLDIWTPMALPTLKIVQPKLRHGALIIADNTVAAKDSYKEFLDYVRAPGSGFIDTTVPFTGGLEVMVYAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN29</accession>
    <name>A0ABR3YN29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-type serine protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_008898</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="323"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="582" mass="63055" checksum="56A8C67D8E1E79AC" modified="2025-10-08" version="1">MSRQYSNDYASGGYPSQSQGYNPSYDYADASARQRQSPSPYYNSTAYDNPSAAASSTYMNSTPPAYSSQQRLADPEAQARNTYGAGGNGRGVSPSPFETVFDDHMYPAASRQNSNVPGGADTSYYGAPNRSPSEDNMLAASVGPDGIPLRDRAGNKLGGAESPDHVYDAPHGGMAGELPPGAGGNGRKGVRFGELGMLGANNRKRIPFVVYIFTIAQVAVFIAEIVKNGILTGSPIMIHPSFNPMIGPSTYVLINMGSRFVPCMHNVNGVQSSTVAIDWPCPNSTTSDASDPSNQCTLSQLCGFNGVPNPLYDGNAKQSPEPNQWFRFIVPMFLHAGVIHIGFNLLLQLTMGRDMERSIGSIRFFLVYVSSGIFGFVMGGNYAATGISSTGASGSLFGIIALTLLDLLYSWKDRRNPVKDLLFIVLDIVISFVLGLLPGLDNFSHIGGFLMGLALGISVLHSPNALRRRIGDDTSYASVSGTYSDNLTTSNFARNPVGFFKGRKPLWWAWWLLRMGAIVLVIVVFILLLNNFYIYHHTCSWCKYLSCLPVNNWCDIGNLQLTNTSTKRDVFSNAAPRLANLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNK6</accession>
    <name>A0ABR3YNK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Maintenance of mitochondrial morphology protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">MMM1</name>
        <name evidence="12" type="ORF">Sste5346_008661</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MMM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21671">
        <property type="entry name" value="SMP_Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03103">
        <property type="entry name" value="Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027537">
        <property type="entry name" value="Mmm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="41"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="156"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="385"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="455"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="555" mass="59119" checksum="B387875241657121" modified="2025-10-08" version="1">MVKDVCPPQAEPAFSFTQGLIVGQLSVVLLVAAFIKFFIFGDPPSAETTASQRASERRSRSDAHRQSLLTLRASQLDQQRGGGLGGGGAQGHGRGGHGHQSSNAHDFLQPRGAAGATGSHQQQLNNRRTSSVLRRPPVLTIGSILNKTYYRVDSHQPESLDWFNVLIAQTIAQFRNDAQHNDAILTSLTKALNGDSRPDFLDEIRVTELSLGEDFPIFSNCRIIPVDEDGYATNAGVGSGGGGGGGAAGLAGATRLQARMDVDLSDMITLAVETKLLLNYPRRLSAVLPVALAVSVVRFSGTLSVSFVPSNPSQATPTKMIFAFLDDYRLDFSIRSLLGSRSRLQDVPKIAQLIESRLHRWFDERAVEPRFQEIELPSLWPRMKNARGGGAGPPSEDVSMSDGGAAAQAGTSGAGAGGVAGAARTGANAVPTSAGVGAGVGSGPGPANSGLDALRQGRPESRDSRDSVATRDTRDPRREAETESWVERQVPPSLHQHQSSLSSISTAQGQSHASGYHQHTLRPSQDSLRFRRRSRHEDAFSMPGSFSDMGIDPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNZ8</accession>
    <name>A0ABR3YNZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="104"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="110"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="44774" checksum="6A5F1FE718E988F8" modified="2025-10-08" version="1">MPSYYHHGRVGSLSGPGVASTNGAVGYYDQLPEGVNSSPAGALGSNAMAAVASYQQQEPFAVGPPLTLGGNLPATVVTSNGRRMSRSGGRSASTSFSVQPPTASGRASSGSWNPQDDDTLIQARARGENWAQIHIHFPGKTPNACRKRHERLMERRNATNDFDARKMEQLAREYMHLRREMWQPLAQRTGEKWTVVEQKCMNAGLKNLQGVSRSSSRRLRIEQSYVGVGGLPAYGGDDDLLGPSVVVGSNGHAHIVGGTGSGDDLLDGHGSPGGSTNSNVGGGNRSVSGGSNSSTVSVQTTHHMGAPSRRHAHSHSHSYSHLQVPSSSGSPGAGTQQDVGSPGAAYPDYYATTTGFSQSLRAMDGAGAGNGTVPSNNGGASMVSPYMGHHQQHQQHHDHPAQQQAHHGQHRLSPDMGIDALLHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPL9</accession>
    <name>A0ABR3YPL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342754" evidence="1">
        <location>
            <begin position="21"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="281" mass="30809" checksum="B6A7238E701EFDBF" modified="2025-10-08" version="1">MPSAKTLLAAALVFPAAVLASSDGPMVPSYEIHLQLDPTVVLDSSYRLVSAVIDEFAMPTTVTKKNVQYIDTVDKALDAQGWSCRIRNIENESGFDLTYKWRLDINNGDVTTALNTAYADGWNSGQGNYEAQVDWYLDSQELSVQRDYTASSSGYSGTDDPTEKDSRSMLIDNAPKMFDNWVSSGWGTTELESGVIYGPVLTKESVGTWNGVELDIEIWPIENSAGTGIDYLVEASFKTDNYTFAADGQTQLIDLLTSKGWFLDASNSKEALVLANYHPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPN4</accession>
    <name>A0ABR3YPN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008629</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019564">
        <property type="entry name" value="Sam37/metaxin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10568">
        <property type="entry name" value="Tom37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal" evidence="9">
        <location>
            <begin position="21"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="466" mass="50028" checksum="4BA041C4302BD582" modified="2025-10-08" version="1">MSLELHIWGPAFGLPSIDPECLATMAYLSVALPRGSWTSLAASPSSIPHTLPALRDNESGQWVAAGFDSIVSFVRSKAATDSSITDLDAGLTLAQTADATAYSAFLRAEAAPLLALSFYVSSANWVETTRPAYSRILPFPLTWLEPPAIRAAYASGAAHLGFSSLDTDNDVSDGDGNHKESSLAAALHAFPDRIRKSVQQQKAEPAQTATEPKPAAKSLSIAEAVSRVNTQSSSSETPESKVQSKLDEAVRACLSVLAEQKGTKRTLIRASGSDDTAPLVSSLTSLDCLAFGYLGLMTVPDVPRTFLRDALRRHHHELAVFVADVRAVCFSDDKSADSSAQIVSTKPRSPRYANPLWLRTLHGLVHSVPGLSGEWMVWLWRRIRVEGDDTDDNSDPAVALWLRDMSAARWQRLITVSATMAGTALFVGLILGYRRLPAFGSRIVVYRRAPVSFAGLGAAGALLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV7</accession>
    <name>A0ABR3YQV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008311</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="74"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="513" mass="54807" checksum="95453471A3FFC7D2" modified="2025-10-08" version="1">MSSSGEKTADHSDVDVEANVLADKPETTLNNTDDTATEKDAVDDANEGVKIVDFDGPDDPENPMNWPSRKKTFTIALVTLMTILSPIGSTISSAAASDIMSHFHSDNQTVGALVTTIYLLGYACGPMAIAPLSELYGRAPLYKICIVWFVIFHVACALAPNLGALVVFRFLAGIGGSCPVTLGTGSIADVVPAEKRAGALAGYVIGSIAGPSVGPIVGGYLTPAAGWRWNFWLMAILSGAVAIIVIPTMPETYAYVILDKKTKKLNKTVPENGPYKSKLDSGRTPREHFAFSIFRPLKMLCVPVVFLQSLYAAVVYSYLYLCFTTFPAVFGDQYGFGSGTSGLVTLGFGVGSTLGVVFCGGVSKKLVAYLAKKNRTGPKPEYLLPTLIVGGILMPVGLFWYGWSAESRTHWIVPIIGTAFLGGGVIITYMASTLYLVDAYTVYAASVTASGTILRCLMATLLPLAGSAMYDRLGFGWGNSVLGFIAIAFLPLAIVLYIFGERIRTTKRFQVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV8</accession>
    <name>A0ABR3YQV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF3">
        <property type="entry name" value="BETA-GLUCOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="7">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="405" mass="43771" checksum="1EBA735AEF582480" modified="2025-10-08" version="1">MAIEHKPDAVRLEGTFTPTSTGAHYFSLPAFGHAKLYVNDELVYDAGPAQDPRAFAEGGPFEQRKQHTFVQGEVYRLRVEVLAPTPKQAIVPLMAGRIAFHLGFMAQDEYEEDVVANAVEAATNADVALVFVGNSAEWETEGHDAADMNLPTFGSQDRLVAAVVAVNPRTVVINCSGVPVAMPWIDSVAGLLQCWFLGQESGNAIVDVLLGTISPSGRLPVSFPRSIQDTPSYGNFPGDQATSTVHYAEGIEVGYRHYDKHPEKVLFSFGAGLSYTTFEYCPAVITPQELVHDGVVTVQLEVKNTGAVDSREVVQVYLAPLLEPRVGRPELPTKVLAGFAKVEIAAQSAASVVVDISFESAAFWDETHNCWAVDEGEYAVLIGNSSTSVKRHGSIKVEKSFTFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR87</accession>
    <name>A0ABR3YR87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Duf1690 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012471">
        <property type="entry name" value="DUF1690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07956">
        <property type="entry name" value="DUF1690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18132" checksum="F62A087FBA108C39" modified="2025-10-08" version="1">MGSGASKPNTPHVWQGSNAPAISQDMLDSLQSSTETDVTRAQTLELHVQARVTDELRRLQAEQLAKLKGLEQAIDDETSATTPSNSTTTASVSKEVAGLRARLEARQREVSRPLPEPVEAARSEVIRCLREHDRRPLDCYREVAAFKEEVRKLEATWVERVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR98</accession>
    <name>A0ABR3YR98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Origin recognition complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ORC3</name>
        <name evidence="9" type="ORF">Sste5346_008234</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20704">
        <property type="entry name" value="Orc3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020795">
        <property type="entry name" value="ORC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045667">
        <property type="entry name" value="ORC3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040855">
        <property type="entry name" value="ORC_WH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12748">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12748:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07034">
        <property type="entry name" value="ORC3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18137">
        <property type="entry name" value="WHD_ORC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 3 N-terminal" evidence="7">
        <location>
            <begin position="94"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 3 winged helix C-terminal" evidence="8">
        <location>
            <begin position="743"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="23"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="763"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="818"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="825"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="850"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="898" mass="98250" checksum="8C77274070C141A4" modified="2025-10-08" version="1">MAAPVGDEAETSIVHKVAYIFNPSDDEDDEANNSVNGGATTSPSESRKSRKHGRTNDRTPKSKKRRTAKGKSKADGDDAQDDGHEEHGEENNALAAFPPLLQGREAPEAIARRKQLFNSLWTKLDDRIQTVLQRSNQATLSAVMDFVEKPIQTKLLAAFVILGPAATTDMLLFRQLSSSFTESEKTINSEKATKDKDRCVRRMVRLRAAEAPNLRAALKTIVQIASSPSSGNGVDGGEADEDDVVAHNGNKYLAYDLEAVAAAITNQSTSRIVVAFEDSEAFDAALLADLLSFLHSWLDRIPFVLLFGVATSVDLFQARLPKQAAHRLSAAQFDVAPSSAVLDRLVRRAVAAADVPLRIGPSLLRSLAERQDEQVTGVSVFVNSLKYAYMCYFYANPLSVFLRDIGDSDDTTTQDNLLKNADYLTAIRQLPSFRRHVEALVADVDIDAAKQLLGDTPDEQQYLRTAVANQLQYQRRWNQRIARSVQLAAASGMFPGRSFTELYITALEDQRGANEDAFTLEEDDTSLAATMTTAIRRMSSVELIAMIRRLVLAVQAGDAELALEAPPENIAEPAEGTDPYETNWTTLSTNLAKIADQIEELQKKLEVTYANRARSRIMMLKAAGSGPSSPGGGGPPQLRSKYTAQSKVLRTTVVAQKVQLSRDSMLLTEEDEAFSELVDATVAAVTGVVDVEPATISRAAAAPSSLASPSPSPAGRLWLQEVWLYDARAPYRDVFIPRPGLVVERALARPHDYLACECCAGTGAPPKKKKKSSKKDNDEDKGSIRPTLPATAILYQLYLDAGPLINVADLWEAFQNAVSDSGNGPRDDKEGDAARNKDKEAAENNSDNAAEGDEEAEEDTQERRHLVQFYQGLSEMKTLGYIKPTRRKVDHVAKIKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRE8</accession>
    <name>A0ABR3YRE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbohydrate-binding module family 18 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011803" description="Carbohydrate-binding module family 18 protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="38571" checksum="524A4CBB4CABDFC1" modified="2025-10-08" version="1">MRAWSSLLVAAASLSGVAADVALDNKIALVNREALLRPGVLEYDNRDSHVVVLPPVGGMFKAKGDANKTEGTVTARSVVDVLLNKRQSCSSGYGYCSSFGRCCPTYDDCCAYGYCIDPEDTCCPNAPCQAGHGCCGEDHCYPEGAVCCGDESYCDAGNHCYKYASLTYDVCCTDSSCTAYVTDGVTVTRTQSYTRTTPPPSTTTDYDYEAYYFTITYYYYYYYWYSIDVTRSVVTSSRTTTRTILSVSATDASDATSSFSDISSTFTPYTPAAATSLESLAGSTTTDVPATFGGGDSGDSSSSPEPTEATTTRTTARGATTTTTTPSPNNAGGGSGVSAGTHVSVSDNILGLWVVVGAAMGVLMVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSC5</accession>
    <name>A0ABR3YSC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1387"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1442"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1495"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1555"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1277"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1296"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1320"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1451"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1511"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1557"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1582"/>
            <end position="1609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1704" mass="171638" checksum="D20F12A7A2CB8334" modified="2025-10-08" version="1">MRLSDLLPGIVALANTAYAVEDLLFYQGMTYAEYKQALSLGYSVKIATQAEWYAMTTADFAQYKAIVVPDADCGTIDQIQFLSDTKATWGPAVGGNVIVMGTDTTYHASTRPGAVALMNDGIKFAASGAGGQTGLYFSLSCYYDDQPFSNIDALSPFGTFVAQGRLSCYDDARIVATPQPSVANAPSQLQLISDSNLSNWSCSAHALIPRYPTGGANGFVPLAVLSDAAAAPGAVGVHSFAGGARGVPYIVARGVTPLGCGDSSVSYQDGEQCDDGTNSNGAPGSLCSSTCQCVFGFDSTKRVCLSQQQNVSSSAVPTSLPIETTTTTTTTTTTSVSVEISIETTTKTQLPSTSSQSVSSSSSSSYPSSSGNVSSSSVPSSSIPLSTAPLSSSFSSGSSIYSSALYSNISSSELPSSSSFSSSSSQLLSTAPSSVPVTSFSSSSPASSFISTNSSSSYPVSSSNLTSSSSYLPTTSLSSISSVYSSQLYNSSSSIPSSSVSASSVYSSAVYNSSASSVLPSSSSYSSASYNLSVSVAPTSSVGPVSSSSSYSSAVYNSSVSSSVPVSSSYSSVNYNSSTSSASPVSSPSYSSAVYNSTSSAFPSSSSYSSAVYNSSASSSIPASSSYSSAVYNSSASTSIPASSSYSSAVYNSSASSSIPVSSGYSSASYNSSTSSAGPLSSSYSSYSSVNYNSSASSSIPVSSSYSSAVYNSSASSSLPVSSSYSSAVYNSSASSVAPSTSSSYSSAIYNSSVSSSIPTSSYSSYSSAVYNSSTSSAGPVSSSYSSAVYNSSASSVVPSTSSSYSSAVYNSSASSMAPSTSSSYSSAVYNSSASLSIPSTSSVYSSAVYNSSASSVGPTSSYSSAVYNSSASSSIPSVSSSYSSAVYNSSVSSSIAPTSSSYSFTVYNSSASSSVPTSSTYSSAVYNSSVSSMLSSSSYSSGYNTSTYSVSPVSSSSISGFSSSSSSVPSSSVSYSYNASTYSVPTSSLSSLSSQSSVISSSSGYNTSSYSVSPVSSSSVSSYSQSLNSTSSSVPYSSSVPLSTGYSSSTFVSLSSPVSSVSPSSFSLNSSSSSVPYSSNVYSSSTSPSSSLSSSATTSVFPTSSSISSSSLISSTASSNLSTSCSTTISGTTTAPPSSSSSYQISSSALPVSSSTTTTDRCGEYIGVEIVIIIDIIEICPNGSSVTITSTSTVDTVTKSICASTSSTSTANCYGCQPGTPGSPGTSGTPGTPSSPGTSGTPGAPGHLGRPGRPNKPGVPDIPGVPGYGDAPSIETTKTTTSSTTVLYPAAPTDGVRRTSPKPEGRFGRLLGSYFGSHNSKDNKDSNGKRSDTLEEGHEINDTPTTIVTSVLPTHRTTVTRTTQHLESLPTAVAVQKKRDDEDVDLSGLWDGLVGGKTNSPFKRDEDDSDDDSSDNTDIITVLLTALGLDTLTGNADSAAADAAKRDTTSTDVVAADAATPSSAPDGPPDARRLGLVEQLLTFTSNLFGRRSAANSATETVAKRDGDPDPSSTGDVTEAASSASDADGLISTLLEALGLGDLLRRNTDDATVVVSKRNDGSVPDVKKRGEQVSDLDSKLSAPAMPGVPATPGVPAADGVPSTPGVPDVPDVPEVPEVPALPKEKRNAEPAVDNQEPLVEDETKDDSPANLPHPPSSLPASFAAFDQKNAVQDSSSGSGSIFTATSKAALSAAALVCVAVVAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YST8</accession>
    <name>A0ABR3YST8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="186"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="678"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1095"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="678"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="691"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="736"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="775"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="799"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="849"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="869"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="891"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="952"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1009"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1124"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1153"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1183" mass="130865" checksum="F61575E22CDB1E51" modified="2025-10-08" version="1">MSIVSGRSSYMHGRPRIIIHDEPPRPAAGSLPRLRPPRRASVHRAPQEVIDDFWAEFQSKRPGKATSIIPQRAYADKAARRIAAQAASGSQSTTASYAEAAAQCRAKVAHIVKECRRVNQKYRDPHFDLELDLQLDRRDCLESLSNVCGIDYGPSSGRGRGRRNPSAAPPPPPPYIAPSFNPQAVKRVDDIFDHPEFFIDGPTANDVRQGRDGDCWLMAALCTLSNKPGLIERVCLAHDAAVGVYGFVFHRDGEWFSEIIDDKLYLTKPDYDESRSERNMLEDRVRINSEEAYRKIYQSNSGALYFAQCENPNETWLPLLEKAYAKAHGDYAAIEGGFTGEGIEDLTGGVTSELYTTDILDKEYFWKEELMKVNDTFLFGCSTGVWGKGRGDRGGIVEQHAYSVMRAIEMDGVRLVLLKNPWGRHEWKGAWSDGSKEWTADWIQKLNHRFGDDGSFWISYEDLLRKYQAFDRTRLFGDDWATASIWTTMTVPWTLEYNDSKFSFTLARPGPVVLVLSQLDERYFRGLEGQYLFSLSFRLHKVGADGEPRSSEEEDAFDYIVRSQASYRMSRSVSVEVDLDAGRYLVLVKIDAQRDDSILPAEDVIRDNVRLRREKLIRIGLAYDLAHSKGRVAETAAEKKARRAAAEKRTARQKERLKKHIMEERALDYLAAKLRLKKQKKGMAKAKAKRKERDARRRARMEEEERAAEEPAREEDSARARTKMDKRDSAIEGANYAGGGVPGGDDGGNSEVGMGQKGGDMPVGDAPVVHEESTKQATAVHSASTDTPADTPTGILADVTTSSNDNGNTTKAAAEEPESPRPVARGQEGGSLQSSPQDRKRLSANYRRPSFEGGRDDGSHNIRHDTRASSRGSRGVQDNSREPSILSHGRGRADGRQRDIPLRGRTSRPASPIHAPIPRGRSVSRYPSPPAFGRRYSRTPPPQRANHPFLGHVDDDNDPRGRRVAPHHPFHAPPGRSANDDSELSSLSSPSDISDDELDFIYKEQSRGASKHNGHRHGAPSGPDGRRGMRPPSPRPVVRDRCGSNESLRGDYGVGDPWNAIAVVGLRVYYQEVDGDGERGGSIIQLGVERAHPFSADRYSGTDDDTGSDTTSLGDTDDDMGRNSDATANSDSGKAGSEGTSDATAGVEDGTSGEEKVLDVDDSLKDATGSIPSRASRRMAGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVJ1</accession>
    <name>A0ABR3YVJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_007089</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="9"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="334" mass="35611" checksum="5E725CB135A5FC94" modified="2025-10-08" version="1">MPSFTVFKGSKEGVKKSTTTKPDELKGDQVLLRVTVSGLCGTDLHYKEQDMVLGHEGSGVVEAVGPEVKNLAKGDRVGWGYQTDACGACQQCLTGHETYCAGRNLYGYHNFDQGSFASGAVWREAFLHKLPDNLSDEAAAPLQCGGATVYAALQGLEKPGVTVGVLGVGGLGHLAIQFAAKMGCRVVVLSGSSAKREQALQLGAHKFVATNEGQTLGDDGEGWTIDRLLVTSSVQPKWDSLLPMMSMRSQIYPLSVSHTDLVIPYLPLIAMGITIQGSLVADRSVHREMLQFAALQGVKPITETFPMTEAGISEAIGKLEDGKMIYRGVLIPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVQ8</accession>
    <name>A0ABR3YVQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">39S ribosomal protein L22, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrpl22</name>
        <name evidence="6" type="ORF">Sste5346_007672</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000053">
        <property type="protein sequence ID" value="KAL1891409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="376" mass="42488" checksum="348E4FF4DBBE3ABA" modified="2025-10-08" version="1">MSLNIPSRRVLATGLRPTTTCTAATTHSALVLRPRTQPQQPLNGATSRPLHTTSPNAISWKGLFGGRKKPASSQSADAAAGLSGDLSRAKTRQELRDRMTNPDLSASPLLASELEQQQQQGVQSTREDGAKKPATSSSARNEIGTSLLQSDLQRALDPDPRSRVRWERKMVVRHVSRLLDPKGQETREERLARTERQLLHKSMPIPTSTKKLVHLARQISGKTLEDALVQMRFSQKKMAREVLWHLEEARDVAVVERGMGLGRVQKKDAEDSESTSHPIKIQTKDGKWLEITDPSRMYIDQAWVGKGIWRAAQAEYRARGRRYTRWSPSSFLSVVLKEEKTRIRQHDERVAKEAKKAPWVHLPNRPVTAQRPYYSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVW3</accession>
    <name>A0ABR3YVW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_007033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="44905" checksum="14A55A9D78C22B37" modified="2025-10-08" version="1">MTDIMSYQYPAPPANGGSTAHMALSPASYHMPMAAADYANGIPQTSSSSGLGQDPHSSPRERRDSLSKSSSHCRRRKIRCIPSPADIQGRCVNCIRLKKECSFYPVDQQPPPDTRKNSTSRSSVGHHHHHLSSTSTAPAAASAPLMPAPAQLPLPSLATLPDPDPRGRPQQNTQPLTMPSIQTMAPPSMKPSGGEPFSPDPKMSGRNSFDYSHSGMPNWMSADASPSSSKPGDMSWRSYPQESPITPAFSPYTTHAAPPSATWTSDAARGSDDLGWSYPPPPPRSLSFGSDTMSSHHGHQQQTYPSISQMTSGHHHTNNGSSHRSSSSSYDRKSSAAAAAAAMSDLYQSPTTIPGVDSIPGTTLDHHVSLTAGAVGTTAYSNWQQPYSYSKDGSDAYVGWGDHNGTPASEGHAASSMYYTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWN0</accession>
    <name>A0ABR3YWN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar-sorting protein SNF7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DID2</name>
        <name evidence="2" type="ORF">Sste5346_007055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="209" mass="23429" checksum="B9D52456EA1CCC71" modified="2025-10-08" version="1">MSQRQLARDMQVEFQARFNAKQARREAQKAAKQDGELRKQIQTLLKKGETQQAAQKARMLLAKQAIATQMDQAADMAELSVAQIQANNAMNRMTNMMAQSSRTMSRAQRSVNPEKTMVTMEQYRTQNEEYAMSNTIYTDAMTQNTSVQVSDDAVHELLGKLADDAGVELSQELNSAQVSKTEPVREAATTEPTAEEEDALQQRLRALRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXQ4</accession>
    <name>A0ABR3YXQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinetochore protein Spc24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">spc24</name>
        <name evidence="13" type="ORF">Sste5346_006601</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Chromosome</location>
            <location evidence="11">Centromere</location>
            <location evidence="11">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SPC24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11565">
        <property type="entry name" value="RWD_Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013252">
        <property type="entry name" value="Ndc80_Spc24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038066">
        <property type="entry name" value="Spc24_Fungi_globular_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08286">
        <property type="entry name" value="Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143026">
        <property type="entry name" value="Kinetochore globular domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 11" id="KW-0137">Centromere</keyword>
    <keyword evidence="3 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="206" mass="22889" checksum="4F7162C4D405666E" modified="2025-10-08" version="1">MLFEEDPSVLIQHTVDNFNTAPDKAAVARIKESLSTLQEARQLQVEQAETAMKRLARQLNTLGAQHDELASKHTAAAHAPTIAHLDTQKFRVAKAASDLEMETERLSAQAADLSAKLQELELQGDDGPLVSNSSSGSGSAPTEDEVLLRLRVYRSLGIELERDGAGHDGEWSRAVIRNDRKGDVHVVNMDKKFSRFFYANYFWQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXW1</accession>
    <name>A0ABR3YXW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TAT-binding protein-like protein 7, AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">YTA7</name>
        <name evidence="7" type="ORF">Sste5346_006623</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000039">
        <property type="protein sequence ID" value="KAL1893191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05491">
        <property type="entry name" value="Bromo_TBP7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="700"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1380"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1505"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1587"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1405"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1422"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1438"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1469"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1505"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1522"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1556"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1606"/>
            <end position="1634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1739" mass="189862" checksum="253900A3C48618DC" modified="2025-10-08" version="1">MPSKRKRDILDFDPNKSDSEDENFVPGDDGERPRRTKKKQKGQKGGPRTTPGHRRRQNRYRGSDIDEDDEEVSDDSLGEPYESESDEDDEDGEPVTTATGRRARKAAVNHLSYKESSEDEDEISDSDRDEKKTNNKKTSPTKKASATIPATPALGRPSRIVVLKTSPKKLRERLGAAEAAAPMTRRTRATTEEADGFVELTNSGRHAQPSRASRSKSPEAYAAGRQTRRASKGLKKPPAPPIEEATQEDSVVFGMNDDDDDEDDEPLTRIGSNGGDGKSLVHSQSLDKIVGDIDVAGDDELALDGAQLDEDAAGDEDYTAVNGDVVMNDDANDDDDDEDDVKPLGRRTTRLRNSIASAAAAAEDGEFTEEVAADAGDEGDQEEGGSRRLTRGSRLRKKSKSVKEQSSDFEPIDDDGSGDGGMSDSDASQKNNNTRATTGDDDSSQNSRGRRRSTRLKTGGKRSRRESDEEDAVDRDEVAMEAEELRNSSRARTRRRRRSPSIVYEETSRRRTTKVVDYSIKPLDQFLVEQEEEEEVAQTPARRRNARGGVNSSLWQRNLMSTFGPFGGGGGAGALIGGPWGTGAAGGVDSDSSDDEMNFRTANPGGAVGGAVGMTPTTGTAPAGFAAPLNLEAITGVTANAGVGKVKNQKALADADPLGVDLNVDFSKVGGLQGHINQLKEMVTLPLLYPELFLRFKVTPPRGVLFHGPPGTGKTLLARALANSVGVGGRKITFYMRKGADALSKWVGEAEKQLRLLFEEARRTQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMDGRGQVIVIGATNRPDNIDPALRRPGRFDREFYFPLPDLDGRRSIIDIHTKDWGLQDNFKKMLAENTKGYGGADLRALCTEAALNAIQRTYPQIYSAPDKLIVDPEKINIHATDFMLSMNRMIPSSERSAAPAWAPLPKAVAPLLDDQLDKIKKLLDDVMPRRKKTTALEEAMYEPFQDADHGFGRENMIQEFERSRTFRPRLLLTGTGGMGQSYLAAAILHHFEGVHIQSFDLPILLGDGRPLEQVIVGLFVEVKRHKPAVLYVPNVDSWYHSLPASAYMTFATMLKTIPPNDPILVLGTCECEREDIPESVLRDFFSYSSKNRFALEKPSRENRRNYFFNFLKHATKNPNDFPDPANRKKRVLEELPIAPPPPPKVKTKEELKEELRKDHLLLNLLKVQLQPIMDQIKKYKKFRQPVIAETQIQYLWQEADPNYVQPDIPTGEPRPFVISHDRDGVRGLLEKATNKFYYNLDLSTIEERLSNGFYARPKDFYHDVVSLAKDARNIGDKERLLKANELSTNVEVDVAEAEARLSQVDWDGLYQRQLKRAKEAEEKATKKKAGLAIFGAAQSSLEDDPLPIIGSDIIPPPANGDDAGAEPISEQQQMQSQARFELKPLGTSTPPSSNGFHHPHLSNGNSVPSVSSTSNGEDVAMVGSDIPVPPQWPRSSAIATQGNTQVSQVSALTGIPAGMSPSAIINEASTTKTSDPSTGPQSTQATNGHIGTTTNNHSILHGNTVSGASGGADAGDGSQIPDTQSIFGSLPSQATSSNDWVHSQMHAMVKGENDNFDGSKSVSGNGEGANGSVAGGAFSSSSQVQAPANSSQQQSPVQPLGPPPPPSQQHLQQSASRLSSQGFPMSVPDASLDPILDTILDRTSGCTVDQLEQISREIMDYIWTSRHERNRSRVINNLSKVFNSTMADMEQVQEGLASPFSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY78</accession>
    <name>A0ABR3YY78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ureidoglycolate hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221">
        <property type="entry name" value="UREIDOGLYCOLATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221:SF1">
        <property type="entry name" value="UREIDOGLYCOLATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="21110" checksum="72D86B0F8104F546" modified="2025-10-08" version="1">MTLSILCQPLRAADYAPYGGVISTDVVTDRTVVVNNGTARRTPEVVPTINKYSEAPSQTPARTVLNVSLASPREVQPWEGEEEGKRVMKIKMLERHRFSTQSFVPMGADIQYLVVVTQNKSECDDSPDLDKLQGFVARDKQGVCYAPGVWHAPMAVIDNPVSFAIVQHVNGVADEDCQFYHLDEEIEIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZL4</accession>
    <name>A0ABR3YZL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_006320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="25236" checksum="17A906019630BE83" modified="2025-10-08" version="1">MQNILQHMISDPELLHPSIHTNLVATQVCAVAMGPNPVLRYHKANTNFPDEARQPVHSDVHYEHPRACFALAVNRIPVDCDAFMGSNEMWLDTHNVTYSRDQDGVRGIFPHLLAERRKVCPPIQPSLKRGSIIIRDMRLWHAGMPNKTEDTVRVKINLIYFANWYRCPMQIKFPPSAKERNEELEKLSGTTIAAQYVEGLNHMTLRHTHDFGQDDKREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZZ2</accession>
    <name>A0ABR3YZZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="62"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="602" mass="66631" checksum="37EEBC7766246294" modified="2025-10-08" version="1">MDAPSPFSGDISPALTITPAFSPLPKQSPFSPCATPDGASPDVPTSPTSAVTTRGPIGDPVKRLFVCCDGTWKNASGTQEPQTNVARLARATARMGRKSGDRPCIQIVYYAAGVGAAKTHHHLPSLLSGMSGKGIEADILDAYCFLSNNFTMAGGEKDDEIVLVGYSRGAFTVRCLASLINTIGLLRRRWLPLLPTLFDSWKMGGQEGAEGLEKITAKVRAAGTSSFIRIKILAEWEPVSATSVLNFVERDATVPQCVENAFVALARDERRFHFSPMVWRQWPGHDAGSGFRNLRQVVFRGGHGDIGGGNTDSGLATVPLLWMVAQIMSVSNAEFDNRVLFETILPMPASKAWLEWGGPGAKDEEAERIKGVARDPPPLHYVDVLRSRGDFVRSTLRRMWEFPSKLGIKTISGDRVFAFQKFVQTADDLVVPTLKTHFTVGLLLGNNRGKLWDTDPSAPDDPDDWAPIHSYEVLMWRRWRKHIQTQKPMPWDLTPGRPGQTRWERAANALNLVELPREAPVATAEQATMENYMTTDTLLGRLLLALNERYPIKGAKSPDEKIETKDENDRDNNRNEIDAVKATKIHELYLNVTYKKDKMLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z050</accession>
    <name>A0ABR3Z050_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006391</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF177">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER MCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="309" mass="33380" checksum="649716AE63893056" modified="2025-10-08" version="1">MRSSPAFVDDDPSYPEGGREAWSVVFGSFCAQMCVFGVINTSAVFQLYFAENQLRMYDASAIGWIFSLYLFLVYFVGMQVGPLFDQYGPRLLVGCGCILLALSMFLLGFCSAYYQIMLDFSVLGGLGGALINSPSLGAVAHFFHARRGLATGLSTTAGGIGGVVFPLLLRSLLPRIGFAWATRVVGFIVLGLAVPATLLVRSRLPPRARDTAALWPDFSMFRNAKFALLCLSIFFIEYGVLIPLAYIVSYAASFDQNTETSYVLPALLNAGSTAGRVIPGLLADKMGRFNVLILSVGLSEATLAWCRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0K2</accession>
    <name>A0ABR3Z0K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein arp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARP8</name>
        <name evidence="3" type="ORF">Sste5346_005942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="744"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="803"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="951" mass="104683" checksum="78667DC82C7D9235" modified="2025-10-08" version="1">MVGKVSERVLLREGLERTDNGMKTTSWPEVTPINQKNYYTEYMKRDDQVLALRVLNEANRDRLVQSAKDRDRALSQNGTIAEQQQGGDLPLGMPTDGGNDISKVIVIHPGSQFLRIGFSTDVLPKTVPMCLATKFQRTESEEYEARPRRQFEAQKIDQQYGEDWSKKYKKMTEDLKADMRLNKRKVLPNSKELVVNYNRRTDPEVIPTHNDPLQVEWTDVNTPVPIPADEVEVDIEEEVVAPEDEPPVTVEGTVKAGEDGGKPADTEAEAEAQAEPKANTDGDVEMADAEAVTEKPQAESEAAATTEAESKPEGETKPEGEAAEVETKDEIVAKTENDDEPKAENGSVPETEQKNGESNGATNGESNGEANGDGKAQEKVPETAQDNGQEEPAEDVAKAKEPTPPPVKRSIVPKIRRKPMPPTVFYGAEAQRIPDDSSPKFRLRWPMQHGWLNEDDYSSVSSLYSDFEAILTHAIQNELGLKKVSSCRQYSCVFVIPDLYDKAYVETILRMCMDWFEFNKVCFIQESYSATCGAGYSQGCVVDVGAQKTSIACVEDGLVVEDSRINLKYGGFDVTETLTKMLLYDHFPYQEINLQRRYDFLLAEELKQKHCTMNQADISVQLYQFHLRVPNQPTHKYQFKTYDEVILAPMGFYEPTLFDSTTKLRGRRKLIDRTYNAYDVDIPDDPVSAAQVAILALDRPSVLPPTVGGLTASGVAGATAEVSTPSKEKQPFNFFARGIEAAGATPSTSKAPSPAPEGGASTPVPAPFVFGAGKDTVNGAASPAPSGRNGGTPAPNGPGGAAGASQSQPAGSGLLQLDPLFHRTAKDIAIERDSVLPVAPLDIAIMTSIQNAAKGDERKLKDYLGSVMVVGGGAKIPHFTTYLEERLRARRLDLVDKILVSRSARDMDEQVVVWKGASVFAKLTTNDSWITPYEYAYLGPRILHHKVLWQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z184</accession>
    <name>A0ABR3Z184_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36773" checksum="913839815FEF1D09" modified="2025-10-08" version="1">MDASKLPNWKDMPKVEGKPHGCAWGLFDKDGVKDELGTLNLLTPEVVKAARDEIQTGHSVALNWGLNRLSEEAFGRHTLKHEIVDWRTKPNYPFYCYDDEISFNTQVGSQWDGLRHWGDAKTGYYYNGIHHDDLLASGKLGIEKWTERGGIVGRGVLLDYVAYAARKGIEYSPMSGHPITVAQLDEMAKDQNVTFRAGDILLVRTGWTKWYDEHNEEEHNKFVANAYAWVGVKGCEETLEWLWNHHFAAVGGDSNGFEVVPMDEDWRLHDFLLSYWGMPIGEMFDVEALAKECERQQRWSFFFTSAPLNLPGGVASPPNAVCVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1J9</accession>
    <name>A0ABR3Z1J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear speckle splicing regulatory protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053246">
        <property type="entry name" value="NS_splicing_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845:SF1">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="4">
        <location>
            <begin position="134"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="449" mass="49736" checksum="3306CFF742C5F8B4" modified="2025-10-08" version="1">MAQPMKIGLNLSKNSKSKPGATSKRPAVFGGGDDSDSDDGGAGVFGGKKGGSKNNKKKQEDDGPVAEAITELGDDFLSGHAPPPPETDRRDEKKLAHRKGQRPLQPPPSKYKSNPTTEDDARFGSDLASALTARKHTEAAEALDPSIYDYDATYDAFKAATSTKKKAGDGDDDGDEVRRKPQYMSNIRKMAEVRERDRRVAEDKKMQREREAEGDAFDGKETFVTEAYKQQQEENKRLEEAERKREEAEAAKAAETGGMTGFYKKLLNRDEERQAAIEEAVKTAASAPKGEDNKNKDEDESSIARARTINTHGGNVAINDEGEVVDKRQLLQGGLNVSARKKSEIERQKERDARNKDRDRDRDRDYGSRNNQGVFSGSKQAMRDRQSQMLASQYEQALKRSRDEEDEQTKAAQEAAKSRKTTADISSAKERYLARKRAEAEAKKAGAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z241</accession>
    <name>A0ABR3Z241_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF272">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37235" checksum="8E8C9D7FEEEBFDB6" modified="2025-10-08" version="1">MSRYAAAHVMNDLKGPGDARPTALDIIRDEKRENEFTGKVAVITGCSSGIGPPTAEALLATGATLYCTARDVQKAKEALGPALVDSGRVHVLFMDHTDLSTVKAAANEIRSREPAISLLINNAGVMMVPTRTETKDGFEMQMGTNHLAHFYLFCLLRDRLEAGSTPEFASRVVNVASSGHRWGLIHLDDLQLAKEGAYSPLAGYANSKIANIYMANELDRKYGNATKSIHAYSLMPGGIRTPLQRHVQAFIEAELKKPATVRYMKSPEQGAATTIFAAVARELEGKGGVYLENCALAPALPANHDETGDSNIDYGYAPWAYDPAKERALWEKSLKLVGLPEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z373</accession>
    <name>A0ABR3Z373_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="2">
        <location>
            <begin position="61"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1218" mass="130706" checksum="2732BFDF3121E4DD" modified="2025-10-08" version="1">MADFASLATSYVLADDEDEQKRLADQAADAIKTAPRKSAAVLGWAQSINQWMPNGDNDADSDAVIRAKALGFLAATLEVLDKDVLRVEQVKHLIAFFGAMFAIDHKAGILAASTALRYLCTMNQFKPTMANAVLSHISKLGEDFRLQVPATRRAIYDLIALLVRNDAALKSLSETSGANGQFLVDLLQLCRHERDPDNLLRWFAILRRVLDRYGPPALAPNVAEEVFKVASDYFPISMRSSATPAGTTVDDLKTALRGVFAASSLAATAVFDFLLQKMDQGDALTVSVKVDILSTIHACIAAFPNPAQTVVPHTSRIWNSLKYEVRHGDVPETIDGTLQVIQAISTRLSRNSSTDTDEATEEDTAALKDFVGTVLADCISDLSNSTFTTPAGRLLTSTMLGGLGAYNLMISSIIGTVKKDLQQAQAANHTRDLVGVLNLVLRTRHALLVATDANPSASATAKATEAEFHTHDDSIVGLLDSVYLRLWNNTLKDTAAAPSPQDPVVLNEVIRGLAALIAQRGPRSSSSSSATAPRPLLCTPAQCTRIFETLAPRILVSYPSVSQSGAADEGLSQTEFLTIAHEAMMALQTATAVYPEGFTFLVERTVSSIAGSPSGPISSYSLMALSSSAESLKSLRDTLSRVAYIGCSTIPYVAEDPESSSRALFHFLTLTQALFTTLERLLDAKASFQATNAVLSGIYGAALNFRDAFSQRGVSPEKAKKAVASASEATAESTAETETLQKLFQAYVNEATSIVRRLYLRATAVDAHQQLSLSADFERNMTSSLTLDDQDEYLHHLAGLATFVVRDLSEEQQKEAKLHEAAFNLFHADYKGPLSFFHAAQGGRADVLGLGILKSLWPSVIASLTDLNISPLNLLDDFDSLDTLPPRTRLVRNNIATVVTNKYSAAASVGPSKALYPGNQAAWQATVEAVKAKLEASDATLTPHRFARLVAIAAGSFARLDKDSKALASLLVFAPARYAESIHNDKAAQQMARILSGLLVSDRTLSTDDHAVVKSIYKQWVYGQTVKALLPLAFPRKSADESEEAAAAARRASTVHTIAILALVRGMPFSVYEDDVAASSGSGNESLVRVLVAAATTLVPQWGDVAVALRVLSAIVTANRADAVRSHLKTVVDASIRVFSSAGPAVTSASPSAPPPPPASRKEALLLVSQLPTHYEEGLLLPYEPRLVRALAAACGDRVREIREVAQKARENWAKVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3T4</accession>
    <name>A0ABR3Z3T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine rich repeat domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="907" mass="98680" checksum="F29DDCDCBAF14011" modified="2025-10-08" version="1">MAHLPSYEEAVTGGHWLDLVAPYVALKDYSKLCRVSRRFYDQFAPRLWNDPLQTVRLLGLHPNDAGTSGRGFSETLRLIGTSFPAVRCIVLSGNTGYDPSDLGHLLNPEDFPEDGSRPMPLILDVGRCGMPLPNNFFHPSYWRQLVYLDMSNVPGSLKGIIKTGTFNQGALPHLRVLKLRGRELDDASLVPIAEHAKQRIWSLDLSYNKLTDRCLRNLFHHCFGVDDLTAQASHYEVEGKLAIVEDVPGETIPPLWRGWFSYIVESVASGTFSHPDRYLADAPVYDADNHNCPSLPRLAGNEPLRSDRAEDVKLALAGGPGQNPLDWHHVRDADICKLPPSLTHLYLSGNRDFTVDGVESIFRCSKGHIQHFDCASPAIPTYGQVPFTLSGILGRSHLFRPVMASNLRSLRVHHSLVTHIPTLSDPSKSPREALAYAETVLCERAEIAYPTVGQGQEEGLGPDWNPRLKSLTLTCLPRVSTGLLIDRLIRFLVSAAEQEAAVREQQAAISAVTSRRRGPTMLSGLRHLRLEFEPYPPQDEDLGDGAFDSLDAKALLNAGTDEGFSFFRETNPAPAAKIVIEATATKMFGDQSLDLSNEEAGKRSERSGESGRGNGVRKSGGAVGAVGTVENASASTNAPRPPDLPGTGGPASPDRLHSSAVTEHAVQARQSKSDRLSHYPLSGALDASSEYVREVVDLGDGNDNQNDNNNSSANAKKKTVQLSVWVGSGQQGTNRAVNAYMANLSRPLLRALIRPATPDQVAAGVPVGACVYNAAWDAILWLPPPPTPPRPPPSASTDENEGEDGGVTPTTSVVSQHGDRYRQDAFRSSLTRLGKSQQVHPRNTGEGKDAMRDVVNAIRQFRAETRSGICRPSGLAPSTSRKTGQQSGEKRDQPRHWAGNLEVLLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Y7</accession>
    <name>A0ABR3Z3Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7908 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057230">
        <property type="entry name" value="DUF7908"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24637">
        <property type="entry name" value="COLLAGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24637:SF421">
        <property type="entry name" value="CUTICLE COLLAGEN DPY-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25485">
        <property type="entry name" value="DUF7908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7908" evidence="2">
        <location>
            <begin position="37"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="478" mass="47366" checksum="0B46221218BF1334" modified="2025-10-08" version="1">MGVLDSLFALFVGSGLLNSDSLSPSSLSSSGLSIDEGAPFLLQVVAKSPYARRHVTKRESSLFVTTSGQTSPACQLAEPFTLVGDQLVLSGNVPVTADPTAACQPFTSFNGSNSISGGFSVNADGTLHWSSSNFSLGNASFCITKANVVYAVFAAGGTPKDCTTVNLQCVPASTCPLPISISGPTAVNINIYNTQNNYYGGAGSSGDGGNGGGSSSSGSTSSGSGVPSVPSVPSVPGVPGVPGASSNSYASAYASAGSESSSSSPDVVVVEGQPGPAGANGQNGDNGEAGQDGKDGSNGTNGTDGAPGPAGPAGPEGPQGPQGPQGPYGYNGTNGMDGINGTSYPSSNSSGNGGTYGGYGYTGCWVVHRETLGGNPVLATEVITESIDECASFCSTANGGRNSLYFTLSSRPSQPGDSDSDTVESVCTCTNSFQGSAITSTTTYACNTPCTFSNADGSTAYCGAYRGGFYFASVFTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4R1</accession>
    <name>A0ABR3Z4R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="318" mass="32856" checksum="AEB9D701D810F485" modified="2025-10-08" version="1">MVRYAFVYMAGLASALPLNINLGAYSPALVVGDGEISFGGNQDVSNLMNVLEGAAVNTAANVANNAAKATGTTVTNEVPSAPAAETTVVAAAAAADPLVEQAQQIANLQGLGNKKEIAPRVQLVQNEADEADDDDDVASVFSDDGESDDESDDEDDAATATAVSKRDLAGFDRALTFAEAALTKGPKVQLGTGKEGSGVGIIVDNTPATATAAKAEKRDVSSSVQESSPKRVRAKVTTMYVRSGIPASLQSKRDVSKVTEREVTISQSVPRSVPVAPVTAPVSSVSRRDAIDAVNLNVDGDQGLTMTFVETVEDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4T5</accession>
    <name>A0ABR3Z4T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c oxidase subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">COX4</name>
        <name evidence="3" type="ORF">Sste5346_005111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="186" mass="20593" checksum="A3D2688709F925CD" modified="2025-10-08" version="1">MFMQRAALTAARRAAVAPVARRAFTTSFIRREAAPPTSTPKIKTLADIKTTDDLLGPGAQPGTVPTDLEQSTGIERLEILGKMEDVDVFDMRPLDASRKGTVENPILVRSAGDEQYAGCTGFPVDSHNVIWVGLSRERPVDRCSECGNVYKMNYVGPQDDGHGHHDHHHGYEEPKTFANFVKPEYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z544</accession>
    <name>A0ABR3Z544_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_005154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="285"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="377" mass="39906" checksum="47E2FC2FFD3B4BE9" modified="2025-10-08" version="1">MGVIGITLIVASIALFIMYPSTWRALAQPFLQWRQTEAAEESPSTATTPSNLRDVKSKTAAVVTNGHATTAPAKTEDSNRTAMPPPPRIRMPTENTEDEEEDEDEEAATPKAVPAIVQNGGAIPTLSLSADSDDEDDDTDNMPPPMFPSPYSAQRAGASADPSRRAAPPTATKLSTASTPTFGMMAPPPRPAVNRGAAALAPVNAARRPANLPIPNRGPPQALRAPASSSSSSLAPPPSSTTKPNKPARKVVLAPGHSPLDWARVASDPVGNRLRGDLPADAPYLLRVTPSQLKQMNGRKGRDAWTALGGMVYNISPYVPFHPGGAGELLRCAGKDGTQLFNDVHSWVNYDNMLSACRIGVMVEEHAATTSPMEEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z559</accession>
    <name>A0ABR3Z559_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acyl-CoA thioesterase-like N-terminal HotDog domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF64">
        <property type="entry name" value="ACYL-COA THIOESTERASE (AFU_ORTHOLOGUE AFUA_1G12060)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="4">
        <location>
            <begin position="70"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="407" mass="44873" checksum="CEDA56801AD80737" modified="2025-10-08" version="1">MARRKTFQESMELIPLPALGSSSSSSNTGALTNADGSSNVARYMSRRAAWLPGSDLRKEMDDLRRNRPGFPVHQAAFGGHVYAQSVLAVCQTLEQEAAASPDSRTDVSGLGLHTIHGYFTAIGKPDRPFVYEVAVLTRGRSFLTARVEARQPLAPSRAATPGDYMVPDDTDFRGEAAGDSPLGFVCFTAIVSFVLPRPHSFGADCQEEPVQQRFASVLSQRAPSKWDPSPPVDIDVLLNVLERRDIVGTFPMVDMKKVDMADWNDEKPLHERRELILYRLLAPLPAGTTPECNNHVLVHAYAADRNGLLMTANHLEFPLNDKVASLSNTFVVHTNVADTAMTYLPTSQTDNDLRSGWWIQEVCFPRAGAGRSVILNKIWSPEGVHVATEYQDGLCTAQEKMLFDFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z575</accession>
    <name>A0ABR3Z575_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005227</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="561"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="68"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="612" mass="65155" checksum="750C14965701F8E4" modified="2025-10-08" version="1">MASNKPSAELQHHDHVDSDNATGLGDGLDTSSPVHPTLTATSEAVIGYETDLTSLPKGYFYSRFFLGSMLAVGLGLLAAVSSFGYAAPILAQINDDLGPDPRYIWISLVYNAVLAVGLALVGRLSDIFGRRYWFIGGGVVGVVGAVVCATAKTIPTLIGGNVLLGLSSATQLSFHYVMGELVPMRYRYIGNAFLYCFTFPGSGCGPSIAYAFIQRPSVGWRGVYWLILGIEGAALICWTLFYFPPSFSKVHASERGERATKTYWAKHFDYVGTFLFTGGFVVFLLGLSWGGSVYPWKSASTIASIVVGAVTLIIFVLWEIYAPLREPLIPMHLFKNVEWVAACVLLGLGAGVYYAFAIIWPAQAAVMYSNGNLTYLGGISNIVGLGIIFGQVIGGMLAKAIGKTKIQCMVVFLLGAIFLAAMATTTPESKNLAIALLTVGCFFIGWNESVCLANATICVRNQREIGVAGGMAGSIRAAICAVLVAVYSTVLTNRLTETVSTEVPPALINAGLPQSSVADFLAAVAVGTAEAFAAVPGITANIIAVGTQAYKVANSDAYRTVYLSTIAFSGIALILTWFAPNTEKYMSAKIVATLHNEHGEVVEKTEKYEEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5S8</accession>
    <name>A0ABR3Z5S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="774"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="138"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="774"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="847" mass="92356" checksum="D62F3E4F0B0BD81B" modified="2025-10-08" version="1">MDTDNYDTSGSSPPRPANTATTSSHLTEAPRFRPRACARCSNSKLKCNWVSEPGEGPCERCARMKAECHLPTLKPRGPRRGNPTRVGQLEQKLDGIMSLLTASKQVQQPAPSTQTTASTTTSTTTATYVDTPPEAQDSPASASTRGASTAAPSPDSSSHSHASQAHSHLQLPHRHAGSGAATPITTATSSPGSYLPPPPQQQQQQPLPSLVPQPPPPTYPPPENQLPSFDSLLRIHPLAHIEVLPGLKVTFTDADLALNEYRKTYSPHFPFVPLPNDLVAFDFFQTQPFLLKVILQVVLPQSPQMQRDGKRWFREQIALHVVTNEEKSVPLLQAILLYVAWSDLGFYIDPKVTPLLQLATGLVSDLGLHRPIHHEMSLTLNAFIADAATALRGFGYDRPPHTLAGIRAMLGCYYVCALSGSFFRRTPAFPFTAYMEQCCHRLMSANEFESDALAVALARMQRVAARIYAVLPNPEVDAPPASAFAPVYMAMATIRKELDQLVHGSSVEHGGPSNASSGGDSDTSGGLHPSVRANCFLWTHYHAILVRLYEPAIFLRLRTASSSAIDLGDSGLRTEALWNCLQATRDFFDAYTAVPPDILGILPLLGTVHLSFGIVTLTRLLSLDAPEWHIGQARRSFNFVALALRLEQQFQAADELEATTSSSAGASTSSTTTFTSPFPRKRRYAYFDTRTILATHRDKMRWIRIWYTTKMPPDPHQVPPPVQTMAGRASMAPTQMGAPQARPSQQQTQAPHTMPWSAESAVAVASAPVPAAVSQPPYPFPTGTTPAQQPQTPQTTNLMDVDTDNPPTPGDRLIISPGGMNVPLEEFDSTFWKAIFDLDSAWEPMAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J8</accession>
    <name>A0ABR3Z6J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mesaconyl-C4 CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="47584" checksum="BE4F5580E2E70113" modified="2025-10-08" version="1">MQLNDQDLNKGLAHETSLARASKPFDVEYLRESMARRPHRATYDHLSPTHSHLLNIALYDVLPRGAQAGAVPDKDLASTLLNPFALPVTKAAAGSLEDHTRVLPAGHHLVYYPLQRPISLLEPDGTDPNQSPGIPFVRRMWAGGSLHFQQPQQLVLDGQRTVCVEGLDTKNMVMRGGPGREKIFVDVVRRYGSGVANLDRTNASHEEVLEVEDAVWQAPALEERRTLVFMRAKDDVPEGTPKETTKPKPKEERVIKAPRAPQYSFPFTPTSTLLFQFSALSYNAHAIHLDVNYCRNIEGYRDLLVHGPLTLVLMLSALRGKLHEVVTKSDVRPPLPYRYIRKFDYRNIAPLYANEELKVCVNRGAQDPGKGFGKWDVWVENSRGSICARGTAITCPDSYEWTTKDADSVSTDNEWDDGWYYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6P9</accession>
    <name>A0ABR3Z6P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004927">
        <property type="entry name" value="MerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053717">
        <property type="entry name" value="MerB_lyase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03243">
        <property type="entry name" value="MerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160387">
        <property type="entry name" value="NosL/MerB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="252" mass="28483" checksum="A2E44BDE125B2907" modified="2025-10-08" version="1">MHTWTTGYGIFPGCASEPYDLAPESKQLRRFIIQYFMDNQSGPNIHTIQKALKFDQETLWHAIDQLHIGVQVMVTPGTELSLLKMPPFSYVPTRNEGTLDDGRVFNLGCAGESAAAHKLFPGQELTVRSLCPCCWEPITTKWKDGELLENDAPDAVIHIGRGPDDWSKNFVYTCENINFFKSHEHVATWEKQFPEKRGATMPIGKVYQWVKPQAEARYWDYDQPPDVVSAKSLVSTSLTGLKKAGFDVSAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6T2</accession>
    <name>A0ABR3Z6T2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1482"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1399"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1619"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1720"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1783"/>
            <end position="1813"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="255"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1183"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1299"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1320"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1399"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1422"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1644"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1796"/>
            <end position="1807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1813" mass="196429" checksum="3D86663455F51681" modified="2025-10-08" version="1">MSFGAGSSHHYRFSDFDEGAFSEHAEVSADQAKRALRAHLAETERRMAEAGRLGTALVQQQKDLTDRLREVEELQSESELAPELKKKLAELEKEYDDVARETARAFLPKQRIPSNESTGSPEGKGGRRSLSPVKYESHASGSPSKLTVSTRKQRNQATNRVHDIEFAAEISTSLISQVRGLQALLAEREEELRDTKQDQARLEDEGESLRDRIKELDESEHRYKEENWNLETRIHEFEAAQRDAADNEKKVAQQLATLLADKTKAQRELDELKATHSRLVDDHTASVKLHDIELGTAKRNMAMADSEKAALQRRVDELAGQNQELARAVSMQHRTRAVESDAVPATSDDDFDTATDNITPEHSPPASPVKGTPRHSVLESETLKTSLLHAQRTLQSLRTNLHREKTEKLELRRMLQDTRDELERSRSDPNGPGSGASKKNRKDPRDLHNKLRSSQLGGARSSRTDLYMLASNDPDWEEVQGDAASPSAVKTRAGPTDASDQFDTANEAQLSDTSFATANDGADTAEDFHTGAEALSSGEDTMTETEQDSSRRRTLIAKGGSSTTAADTSAEMLDNDPANQSTASTSDDDDFDSPRTPTASLSANGVSRMRLRVSRSSLASRRLRHMSSVDEVGSSPVQGSPYSAAGSPATMAALTPGSMNSTPRAAGPQQSLFAELGELGEDSDEEVVSDGTPSRVRSPRIIIPSNFGSARSTSSNNSIAHSPLTQIGHSPKIVMVDRSTLTDAVTILPWSEADDKKEQAGLGADLAQDSRPNSFVSDDAVDMDEKLKEFPSPPTSPPGLGTVAAAAVLAPAIAEVTTRSIEAGPDSEPAVEFTVSDVFSVPIEPVATPIVPVDFTVSGIVSMPIEPIALPAVEFTVSNVGLMSFEPVVEPESPKPSPIILGLSSVQVEHVTPKMPPTPEPEPIPVFATSLLHAVDITPIELPEPVIPVPVPVVLPKVGPPTFTFSAIEKQHVEPVAEPEPEALPLDPLSFSTFHAQHVVPISEPEPVVPPMEPFTFTLLQTQHVEPIAEPEVPLPPLPQFSVSNIQHQHVEPVSEPEAPLPPLPQFTFSSVQSQHVEPIATPEKPIPKMVVSNVLSHHIHPVIEEEPEPEAVPVPVGVSTETQTDEWKPESSLASAGLIGAGAALLGGAATAAALDDDNVPRSPKRNGFIIPRDFDPILAEQNENTRPTTPNKNNMNSLLGWSKAKGPSTPVIAEDETRQSPNASPVPETPESQRPFKEISVNANAPRSGAYGQTQEAADDQNFMPASPSSPQSVIRDETFDNTPRFKAIAPPEHTRTASQDSNTGSVRRAKHSDAIRNEIAAAALASSRRPGSSSSNRRTSNDFALPPLPANHREVIEAARTGSAGSMAEGVPGPATWRVRTPTGSAREPAFAIQGATPTPRANSRTAVIGDMRPPSRPASRTNASQAGASAVPNTISRQTSMSSFASEVDARFNIHDGTDVFGTGHTYTDPRMIQAITQTMIGEYLWKYTRKTGRSGLSENRHRRYFWIHPYTRMLSWSDHGPTPGSRSEQRAKSIPIEGVRVVTDDNPMPPGLHRKSLIVISPGRTVKFTCPTGHRHEIWFNALSYLLLRNDEVPPNDGMTANGEPITREDVDEFNPPFAGQRTSAAAGAPQARRRPPVSLSSYNSRTTRNESPAFDMSMNHPTLTPTHNKKASVAAAGSMTPSTSVAGLTSRSRLSRIGGYWRSSQSLSAQFNSFRGRSTTPLGHRHTNSGTQGSGIYEASEMNDSAEELRAMYEAQDRASDRLENVRACCDGKHDVGMLSHSSRRHRHSNGPSSVMSTPTHSTRHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7G5</accession>
    <name>A0ABR3Z7G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HpcH/HpaI aldolase/citrate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="5">
        <location>
            <begin position="93"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="330" mass="35050" checksum="5C9995C0AB03B862" modified="2025-10-08" version="1">MASRALSAFRRPSQLRTLGLSSNTTSTNTARRSYQTSAPPASTKPLARDAMTQANPLRQAFTRFRSTDGSARGQASLGMWQMLPGANVSRALARTPGIDWVLVDCEHGNIDDAAMHEAVPVIAAEGASPIVRIPDLQSWMVKRALDTGAHGILAPLIRTVDEVKDFVAACKFPPQGRRGFGSPLAMQGFRVAQKGDATHPVALPTFTEYLDQANASVLTIVQIETREALENVEKIAPLVDALFVGPFDLANNIGHPIRDGVFPAEVKHAMARVLAAAKAQPNCCCGVYAGSPEQARGYAAAGFHMVNVVTDVLTLQAAASAAVSIARGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Y5</accession>
    <name>A0ABR3Z7Y5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005032</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="811" mass="90544" checksum="A7D5C537AAE3798C" modified="2025-10-08" version="1">MSNIQGKASTPLMQRRRRDTSSIACNMCRTKKTACDRVRPSCALCIDRGSRCVYRTNYRTSDAAAAGASTVASEALQKQLDVLQTRLSDQSDMVQALAALPPEAAVDILRLLRTTKEPFSVLASLHGSMHTRLRPSENRMSRSISPPTYSQMEFELAARYRAVYARLEPVDDASLQSLIIIQGAGDGSGFLGGVGSLSPSTSSFGDTSSFSTTPTPSASVGIDSDTPFAASPTPQTSTPRRKSRRYIDDRLQLVQIEYWTSVIISNEMAASILSFYLEYDHTLFNIFDTDLFLTDLVECRSDFCSAFLVSSILFFACQAYTAIDSTAAPLVHAFFREAEMLWQGQGNVPSLTGIAACEIFSMGGYFYGRDSVALAALIQGRRMAEKMELLSIAQCSPTTIAHFQQQQPKWLRAASHAAWGVHNWLSAHVFYYNGEAITHPPILPAPGNTEEQYSDEFKKFNLKIEWSSYTSKSFPGISQFWAISQEVAVVYLNQRIDRNRPLAEQVPIAFAEEKYRKLLAWADAMVDVIYDRQTWQLLVCQCWFHCTVLHIFRPFLHEKVPGLKNTPRPRPLGSFAAMDGSPETVFDASVQQLKNLVYIYLSNLSRIPLSGFFNAAFVLVGHSMIQGYRQKHRISTPSSRLSISSQSSEMLVDVNTADLNSTNRVVIEEEDGEEMEVVRQTPREVAEDKKMLRMYFLLCVRAWTDLYMCFPTFSEFSQAFLSMAMEAEIMTGAEAQSSLARLRANGRHHDDELSKPAGVSSLIDFDRSLSNPEEASVNTLAQRFNDLATFSELTNAEDFVAAPDDLRVQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z890</accession>
    <name>A0ABR3Z890_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="27887" checksum="97B346C2609B262D" modified="2025-10-08" version="1">MNTNGVFSKLHDFDLDVPPDLDLNDIGPMLSKLGSTSSPTSSPTSTSTSKKEVDFPWNMGLANMDLNAMATSDHFALLHSTATKLYADHAGTLQSLGASIQPHLRGPMTPVLIIAVSIMVSLLVSFIVSIIQMAVLACVVVYFFPSVVAAVSAGAAGAPTGRPGAAAGKSKPVASRTPVAAFAGVLAASYAFSSIATMVVLASSAYAYLNHYAVAAKNSAANNNNSSSNSNNSFLRPDARSTRRDERSQSHSSMFRRISRHRDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S9</accession>
    <name>A0ABR3Z8S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF6">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="660" mass="76978" checksum="66B1ED8C4DA41585" modified="2025-10-08" version="1">MLSFLDLPESARTLVYEYALVRFERNCPIDLSYWQKRSFQTLEEQEYQLRRGMHQCWRRANTYEPHNRTCVCEPLPLALLRVCRTVHSEAVQVLYSENKFVLRGRTFTSRLIFGEMSYDNHHDDYRLQRLPPAIQFAPLLGEIPLYGLANMRSLLIRLNCWPCPLGHEEAIFTDWYHDNPFEDFDDESANPTSFCRFCNMRSDRADDPLFLTETEEGAKLTQNLAKNKAMLKVWDDVCEQLGLALKQNPHDRPQLDLTFICDVDSAEDAERVVAPLKQAVISSAGTRLRNCTIRLGRDRQDADYTAVARRTVQTLKTGVEVHEEAGDITDTRHIFPFKRLPAELRIKILEYTDLGRLQRAFFRNGRQFFASTNYMGVACCNACTFTRMDCCCPRYYSSVSVHCKCAFLPTELFKVDRQMYHETAQDMFYSKASLEYHSDNFDITLQALKRMTPNTLKLITKLKFVVSTEQFRMWRKPGHRMYVDSDDEEDSDIPSFVWTPNPYRGDKTWAPLVAFISDNMDVSRLSIRLNFIDCVWDKFESYLMSDDTDDLHHEFHDAYCMYMDLVNEVCTLEDLKGFAIDISVFENMEHWFVRQVLGDRDPYKGGVTEEEIEKMHANKRGRRAHRFMPVYHSTNIPLPNSSWVPPVEMGRELDTEAGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8X3</accession>
    <name>A0ABR3Z8X3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854077" description="DUF8021 domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="2">
        <location>
            <begin position="174"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="292" mass="31219" checksum="C22E58F2C8167A89" modified="2025-10-08" version="1">MKKAIIAALVAVVRAAPFGQSDLDSLPTTCNQTALAEAADAYIAAQTAGQLAPLLAITAANWTYLENNQAVSISTTGSATGSILAKALKLDHRRTNFDLTACATYTELVSAADPANPYVIGTQIRHSTDPSAPQKVVSIDSIVSTTGAWLFDAKKTLDHILHENWTTILPASARDARSVLQAAGDAYLDMWSNTTADKAVPWGTPCTRLEGSAYTGRGRPDDSCKAGIPSNHNQAPNTHRRYVIDEAMGSVSVFCVWEHMMNAADSHELRLEGGKLRYVHTMTSCGSKVCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9D3</accession>
    <name>A0ABR3Z9D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein atg6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atg6</name>
        <name evidence="6" type="ORF">Sste5346_004491</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="182"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="313"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="185"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="538" mass="58439" checksum="4B0140FA84D2EB73" modified="2025-10-08" version="1">MYCQKCRTPLKLDSSLEDLNPAAYDLLVATASQSPHRKRQQIRPANAPDADRRALYDQVSKHAGPAAFKRYGGGGSGGSNSSGGSGSGGGGGGGSMRDSSAMSFVLLSDSTIAGGPNHGSNAATAGFSAPAPMRYGIQSGDKNANAGALTSHDDDDASKAQGMERITKLFEIMSARSDVDHPVCVECTELLVEGLQQRLDAATRERDAYVSFLKKQQANVPNADELQAQAAALTQAKQQEADAMAELLQLETEKGRLDDEIRALELETQELDRDEEQFWRERNAFASKLADFQNERDSINAKYDHDARLLERLQRSNVYNDTFCISHDGTFATINGLRLGRLSSRPVDWPEINAAWGHALLLLVTVADKLNFRFENYEPLPMGSTSRIVRYEPPSPTSSRLADGRGGGGGFGAASILSQRLSAPPQAPKKHVLELYSSGDMPLGLTFMHRRFDNAMVAFLELVRQLGVFVHQQTLSDDQHQHPLSLPYRIEGDKIGDVSIKLGIAQDDGWTKACKLTLTCCKFLLAHASNVNSTGRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q9</accession>
    <name>A0ABR3Z9Q9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">POL12</name>
        <name evidence="10" type="ORF">Sste5346_004136</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="9">
        <location>
            <begin position="238"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="8">
        <location>
            <begin position="396"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="78"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR018300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="692" mass="74386" checksum="6182715A2F2F5569" modified="2025-10-08" version="1">MADTVARLNERFGAGDAQPLEPDIVVQLQSIMNMHGLPVQELFYKWEAYCIKMDLPLDQAALTMDRLRAFKQNLQDALERRNQEQQSLPQVSSHAKKIKTERLGGGASATPRRSNKGGDVYGLLDGIVAPSTPGSGGSVTNPRTGSTGKKFTSGTPNAKTPSKLEDQLNALSGGNLTPASPFADRPNAGEVVEVLNDHLPAATPPIVPYAQSRIKLTAASDQKKLAYKPLAMKLSEASEILDDRIDEFTTLVMDHHKIDYEAFGSAASQSTSEIVAVGRIASDAAEGKLNAASVVLETSRRMGGGLRVPLDLSRYRSGNGGFQFFPGQIVALRGTNSSGSAFSVTQILDIPLLPNAASTHATLATHRERMRGGDSADDMDVDGGDGTTKGPAPLNIMFASGPYTADDNLDFEPLHTLVSKASDTSVDAVVLAGPFIDADHPLIATGDFDLPEDAVVDPDQATLTTVFRYLISPALQRLAAANPSVTILLVPSVRDVIDKHVSWPQDAFPRRELGLPKAARIVGNPMTLSMNEMVLGVSSQDVLYELRHEEVTGGRVAESNAVARACRYLLEQRHYFPLFPPMDRRKLLKTGVDDGKGLATGPMLDTSYLKLGEMVNVRPDVLIVPSTLPPFAKVVESVLVINPGYLSRRRGAGTYARMTLYAAEGEDAAPSVGTTMVGHKIFERARVEITKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAJ5</accession>
    <name>A0ABR3ZAJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003924</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="182"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="414" mass="44990" checksum="6B60A452FB3A40BB" modified="2025-10-08" version="1">MDIKSLQAISDAAIDETNDALREINLSLHNNPELMYEEHHAHKILTDLLEARGFDVERGAFDIPTAFKATYPPRDGAVSGRTASINLEYDALKDIGHACGHNLIATAGLAAALGAAAAIKKGKINGRIIAFGTPAEEGGGGKIKMIRAGAYKDLACNLMVHPMSDRSHNNAYSSTMCGSELNIEYIGKPAHAMAAPWDGVNAMDAVTILHTAVGLLRQQIMPSDRIRGVILSTGEQSAVIPERARARYCVRSASLARYRVLKQKFVNCLEAAALATGCELRTSWLPAYWDIRTNDPLADRYVHHVQRTDETSVFRSVLEQKYDRDCYSTDQGNVTYVLPSIHPTFVIHSPEGSVHTREFTAAAATDDAHRRTVAQGKAMAAVALEVLVDDAFAAEVKAQYDAMDLSAADDPFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAY7</accession>
    <name>A0ABR3ZAY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Sste5346_004143</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05304">
        <property type="entry name" value="Rubrum_tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026255">
        <property type="entry name" value="NADP_transhyd_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00561">
        <property type="entry name" value="pntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006942">
        <property type="entry name" value="PRK09424.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="666"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="716"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="779"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="818"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="874"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="898"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="15">
        <location>
            <begin position="119"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="14">
        <location>
            <begin position="264"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1897407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1124" mass="117209" checksum="8547358029E07C40" modified="2025-10-08" version="1">MAASWSLLVRPAVAHTAIPLPAPVERLSRRCVRRVCDNAPPRKWQHSLGHSRLTAASTSSLALTVLPRRAAKSLQLARHASVLSGPPPASHKATVVPANATFSTKVIPPTTPYAKLTVGAPREIFPNERRVALTPQNVALLLKKGYGRVIVERGAGAEAGFLDAAYKQAGATVVDSASAVWNEADIVLKVRGPTLEEAGNAREGQTLISFIQPVQNKELVDVLAKRKVTSFAMDMIPRISRAQVFDALSSMANIAGYKAVLEASNHFGRFLTGQTTAAGKIPPSKVLVIGAGVAGLSAIVTARRMGAIVRGFDTRPATREQVQSLGAEFIEVEGVEEDGSGAGGYAKEMSKAFHDAEMKLFSEQARDVDIIITTALIPGKPAPKLLPTYVIDNMKPGSVIVDLAAEAGGNCEQTKPGELATYKGITIIGYTDMPSRLPTQSSTLYSNNVTKFLLSMAPVEKEYGVDFTDEVVRGSIVTQNGEIVPTAPRPAPPPPPPKPKEIVVEEVVPLTPFQKVSREVGLVTGGMTGALALGKMTGPLFMGNAFIFGLASLIGYRIVWGVQPALHSPLMSVTNAISGMVGVGGFFILGGGYLPHTIPQMFGAASVLLAFVNISGGFVITKRMLDMFKRPTDPPEYPWLYGIPATLFTGGLIAAASTGAAGLVQAGYLVSSLLCIGSISSLASQTTARMGNILGILGVGSGVLASLLAVGFSPEVLTQFGALAVAGGLAGMLIGRRITPTDLPQTVAALHSVVGLAAVLTSIGSVMADVSHASTLHLVTAYLGVLIGGVTFTGSIVAFMKLSGRASSRPLMLPGRHLINSGLLAGNIATMGAFLAMAPGSPAIAAGALAANTAMSFLKGYTTTAAIGGADMPVVITVLNAYSGFALVAEGFMLDNPLLTTVGALIGVSGSILSYIMCVAMNRSLTNVLFGGIGTVAPSADGEQKKIEGTVIQTNVEETAESLVNAESVIIVVGYGMAVAKAQYAIAEITQMLRSKGVQVRFAIHPVAGRMPGQCNVLLAEASVPYDIVLEMDEINDDFSDTDLTLVIGANDTVNPIALEPGSPIAGMPVLHAWKSKQVIVMKRGLASGYADVPNPMFYMPGTRMLFGDAKVTCDAIKSAIETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB09</accession>
    <name>A0ABR3ZB09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyruvate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_003698</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02002">
        <property type="entry name" value="TPP_BFDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006203">
        <property type="entry name" value="PRK08327.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF164">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="6">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="4">
        <location>
            <begin position="215"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="5">
        <location>
            <begin position="439"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="64238" checksum="390568FBB1821CFE" modified="2025-10-08" version="1">MSNYTTATAILEALEDAGVTHLFVNLGSDHPAILEAISKREADTKRDGAKKNGLRFFTAPNEFVGLCAAQGFFQASGRMQAILVHVDAGTLAMGGAIHNVSRARIPVIMIAGTSPVTDEGELVGTRNEFIHYIQDTIDQRGIVRGYTVLNHEIRTGRNAKQLILRAAQMSQSEPKGPSYLIACREVLEEQITPYTVNANKWRPLSPGALAPAAVEEIGKALLGAKAPVVVTSYLGRQPEAVHQLIKLCEATGTAVLEAVPGYLNFPHTHKLYAGNHWSEGLPNGILGGADVIIVLDCDVPWIKSVFRPSPDAKVFHIDCDPLKVNMSLFHIDTELSCKADVLTSLEQVNGYLALPRDGDTAALQTYQAAVEARTAKVAEIHDTYIAGIHAKEVLPADPSIITPHYALSRLRAHLPDDALVMSEGISNFRPICDVLMRRLPGTYFTSGATCLGWNGGASVGAKMAHPDKLVVNITGDGSFMFSIPETVHWMARKYDAPFLTVILNNRGWKSPMLSALACHRQGHSSQAETADDLYVTFDPSCDHAQVAVAAGAGFGCTVKTADEIDAAIQKGLETVAAGRAAVIDIWLPKFQVGDRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ9</accession>
    <name>A0ABR3ZBJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045673982" evidence="2">
        <location>
            <begin position="18"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="404" mass="37071" checksum="61202691B8A4CE4D" modified="2025-10-08" version="1">MKPSTLLVVASLTLAQAAVVDRPGNVKRDFISGLLSSLGIGGNNDANNDNGNGNGNGNGNNDNNNNNNNGKDRGDGNGNGNGNNNANNNCPAVSVSTVTARQTITVGAAPADTANSTVAAVSAAAAPAAASSSAAVALGAAAVSAAPATVTVTVSAAGTTVTETVSVTVTAAGAAVPAPAPVSASSAVVAGAAAAVSSPVAVAATAASVATVASAAAAPPAAAGGPAVDGVPTGGVGVTVVAVPGSAHTSTKVVAPAVSSAVAVTPAAVAATSNVAGAAAATLAPLSSSSSSALAALPPLSSAATSLAVQPAAVATPATSANTLVPLGGSTAAAGLPALTAITSINSLQTTVALGPAQTTTAPVAAAPAAVANNPQELSINLSGLSLNSVLTLGNLAAQTLVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC11</accession>
    <name>A0ABR3ZC11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="559" mass="59695" checksum="0F4E2F05E995AD09" modified="2025-10-08" version="1">MLDENLPTFIFRPMPDHPSSSVVYFTRSGSDPAPEYVLRIADPVSKPACRGVYAAALTDPYNSNDVVYGEAAVTPEWQQPTLSAAELRDHRERGTEAAGASPTPKIPDSFAISLYNPDQSVAVRHTSSGWNRTESWEFEIPIETFRAPSASRLDRQQTIPDSTASASAAGDAGVNVTPKNAFRWKRDGRLGNKDMTCYMTGQTVGLQRSKEPDITVALFKHGRDPAVTIYEPNLQRVDVQDRKGLDLVLLLSAQVIRDLYLVPRSDPFNMDGGAAAAGGRRKNSRPAGAPVPVPVANLVPGSNAAGARPQSTYNEPAVMTSAIPSGPGGPVGGAGGVGGGRVAGSTPSAAAIDAETKRLQVMLEREEKERVKREREEEKRIKKMLEAEEKEQRLRDAEIAKETERLRKMYGTEGQDLPSTVPPPAGPPPSSNASRPVPPPPPPPASSYAGYPGNNGYYFPPQQQQYLGHPPLPPRPVSAGPSSQSNSSSWWQRPGSGSGSGGGAANSGSNKKTSGFLSNPAASVSGFFSSSSSGNRNRSSSAADGDERSRIQKKRSVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC58</accession>
    <name>A0ABR3ZC58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF1">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="68"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="232" mass="26628" checksum="CD7FDADC81CA8406" modified="2025-10-08" version="1">MSSSSEIPAVAASTSAEEALPCVDKATEKKADEVAPDVDTQDAAKAEEEEPKLPPLTPAQFREYNRMAEHMDHFHNHFRQVWTMIYDACEKRKRPAGMSIRQFLDEGLQFISYLTTHHSIEESYVFPMLAKRMPEFQPPTKKKSGAATSKGSAKAAQLIQQHREIHEGMDAFEDYVRKCRNGETELEMTSLKAQMDSWGKVLWQHLDEEVAALGAENMRKYWSLEDMRRMRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCD5</accession>
    <name>A0ABR3ZCD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1898004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="49"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="428" mass="45110" checksum="A7A71D54FC83F916" modified="2025-10-08" version="1">MVRPLSLALLAASVSNIHIPQLATTIAINLPPNSNDINFYMTAPTYYSYVAFGFGSGMANSFMLIAYPAADGKHVTVSPRLGTGDTEPQFDSNYHVRLNSNSTIYGSYIVASGTCVNCRSWPGGALNSNTNNQPMMYALGPAYAAHLASNNQGVTLQKHEAYGRFLMNTIQATGYGGTGVLTSIDNQVNTGTQPVNTYGANSPNGVVINDRDGLGLAHGIVLAVAVLVLAPMDIILGSGRLLASFPLIHAVCSLLYLLMLIAGLGTGIRASFEYVATKHFATAHQVLGFITFFMGLLLLGLGIALHVGRAMSSSGERGIVTVVHKWGTRFLWLLILIDGGLGLKLADASLGLVIGYSVLSGATFLAVVFALACLWCIGGRRTRTRDGAVADGGGGPVNFGFNGRKSVNSRKTSGDSEPVIIPENRHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCS1</accession>
    <name>A0ABR3ZCS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003396</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000015">
        <property type="protein sequence ID" value="KAL1898493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="306"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="400" mass="44392" checksum="2FD5251C74C0DADE" modified="2025-10-08" version="1">MMHPGTALAFATWAMTVLCLALVALRLYTRVYLVHFVGAEDYLFAATAVFFLIFACSIQVAVHFGLGQSFWSLSLQQSSDAIFWTYVANTFAITGNAMAKLTTGLFLLRVVQLRWHKIALWCLVGVTASTSTALTIMLWNQSTPVKMSWDPFRTAGHWNIQIQPMSVGLGVWSSACDFFFAAFPWLFIWSLRMQRREKIMLASSMSLGVIAGVCGIIRTVVLARLNVLNYTLTFVTYFAWAGAEIAVSMVCLAIPTLRPLYLRHRGLAVNSTHPRHPADDVLPQFTMCGPEAPATLDPPMKFLADLESGPSSMESTPRSTPGSTPNSVQDEKFDSLPEVEILPSRLPKAYLSRGQDSVDEILGLYGQNYAYGQNQSHGQIWIKNEVSVQESTATNWPLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD01</accession>
    <name>A0ABR3ZD01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="209" mass="22268" checksum="93433B97D1BB4CE1" modified="2025-10-08" version="1">MDAQPAIPPRPLLVPPNTSHKMDESMPPPPPPPPDAGTPSSSPPPPGKKTLGGRFRELLYPLAIAVTSFIISFVVGVGAALAVATGLASSLLALVDDGIAYGWQLFDVYQRLGLLAVAGTFANAIATIVDNRLEEVATKYKPESFDTVIKGLLVGGRENVPAYRQYPFLGMILVPAMTAVLFVFMFGIRIVRNLRGYQALVNAAGQLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDW9</accession>
    <name>A0ABR3ZDW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ammonium transporter AmtB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003826</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF9">
        <property type="entry name" value="SIMILAR TO AMMONIUM PERMEASE, BUT NOT NORMALLY ACTIVE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="7">
        <location>
            <begin position="8"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="400" mass="42894" checksum="D91F3B90CA9CAAB4" modified="2025-10-08" version="1">MASVSEFFVCWGIIPAVGLGYSGYSTKKNSLASFYLALLAVICCSVQWYVVGYSLAYSDGNGFIGGLTYAFHRHVLSEPVGTIPAILFSEFQLIFCAAVAAIAVGGACERGRLLPLVPFLFLWSTFVYCPLAHMVWSDNGFFSRMGVLDYAGGTPVHICSGATATALSVYLSHPLFRSRLSKTRTPSHMKLHLPQNTMSQLLALITIWGAWLAFDAGTTMSLNFKSVMAMCVTNTCAAMGALTYIGINYYETGRFSLDSTFLGAISGLVMITPSAGFIGMGTAALFGVVGALVTHQALRIKMTRFALAIRWVDNGDSFATHCIGGFIGTICTGLFASKEVAAYDGTTDIRGGVFFDGNILQVGIQVLEAVIGFTWTFSVSYLLYATIDCIPGLEVLAPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFK7</accession>
    <name>A0ABR3ZFK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="47343" checksum="1FAC0462AD85BD39" modified="2025-10-08" version="1">MSKEKQSQPQSLEFVSFDGLKAWVFDQEEYERRTGKPVPLTDEQRRAIAVLAPPPPPPPAVVTNWDDVDTISLLMRYLQARKSSKGEINYPEFLSEDVPGPAGTIHWRTRCRLSVEAYGHLFPPLNHPRPSDCIFTTKKASRQFAARCAIEWLVAQGRMSADGEYIEPLSKSPAKGIANATKKIVVASKPVVNKPVASAAVVGKPVVNNTVASIPVKQSLPRPLKQVPPQQQTVIQTAEASLVTESHDLITVGDSQYGGGSIEAVIRQQQEWQQLAEATPRVQSMASYAAGGGGNGGETNTGRSGQWNLVMAAADNGTNATNGRGNPPSVNERPSHFRSHGNDYEVSNIHMLDQLCRAMKLGSPTYELRPSRVGAEGIFDGRIVFSPPNAKGGGPGKVPNLPAGVGEVYDVFTKKAAREKIAQSVLQYFNQDMRGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGS7</accession>
    <name>A0ABR3ZGS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SKO1</name>
        <name evidence="9" type="ORF">Sste5346_002747</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002112">
        <property type="entry name" value="Leuzip_Jun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021755">
        <property type="entry name" value="TF_Aft1_HRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021756">
        <property type="entry name" value="TF_Aft1_HRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020956">
        <property type="entry name" value="TF_Aft1_OSM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11786">
        <property type="entry name" value="Aft1_HRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11787">
        <property type="entry name" value="Aft1_HRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11785">
        <property type="entry name" value="Aft1_OSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00043">
        <property type="entry name" value="LEUZIPPRJUN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="445"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="470"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="218"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="560" mass="58071" checksum="1BFE757EE97F3E0F" modified="2025-10-08" version="1">MAKHSPTPASRGTSKSPKQKTKSSPLRTETSAQKADSSNAEPAKPLAPPPRPNQQTGNTPDYFASQVGGASGSLSLEPNPFEQSFGGGSGGAVDTSNGTKLPSVAALTSPSSLLPGGTTPSFNWGGGSLRTGPLSPAMLSGPTNDYFGDTHLRGGFPTPNESSLRTGLTPGGSGSMFPAPSPSSQAVFAQLQSGGATPGTLDFHRTAMTAAASKREQQAQLANQANQQQTSAPTSAPQEPAATSAAAPKAEAKTFDQDSNAANSLYLLAQGRGSAQPQAQFVAPPPPQPVSNTAVPLPPTAGMPAGPPVNQTPVPIPVIPGQNGRALNGTSLTNGHAATNGSAPARNGRGTSEAVSAASDDSEPARPNTKGRGKRNSSGDNGSAANNRRKASDAPAKGPAAKKAKTAASASPPHDDMYGDGDSQSDDDENRLGKDGQPRPKMTEEEKRKNFLERNRVAALKCRQRKKQWLQNLQTKVELYSSENENLSSQINQLREEIVNLKTLLLAHKDCPITQQQGLHGTYLQQSIEPFNPQMNPYGLAAPIANQPVIAGQVGARRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHJ1</accession>
    <name>A0ABR3ZHJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF17">
        <property type="entry name" value="STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35436" checksum="EEAAB17C2C12CD51" modified="2025-10-08" version="1">MASAAFLGLTNYNSSPFWSNAVPCALASLAVQYAVGLPSTFLINPPSERYYDLTGALTNIAVAILSLYLPRWRAEDQLATASNGAALTLEPPNWRQVALTGAAVLWAARLGTYLFRRILREGKDSRFDAMRTKPAKLLFAWTAQALWIVLCQSPVTAVNAVGAPVIATAKSGDAPSTSVLPAGVLWTDILGFGLYAFGLVFESVADYQKSAWSAAKHAKQHDEPFISRGLFSLSRYPHYFGETTLWTGIAVAAAGVLTREPIRLALGGISTATAVSIAAVSPAFTAFVLLKLSGVPLSEPKYDKKYGKRADYQKWKKETPKFFPKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHK6</accession>
    <name>A0ABR3ZHK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MDM12_2</name>
        <name evidence="9" type="synonym">MDM12</name>
        <name evidence="12" type="ORF">Sste5346_002461</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="67"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="243"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="488"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="575" mass="62274" checksum="B4C7132773D54E91" modified="2025-10-08" version="1">MSIDLNWETLTTGPDGQELAHRIRDFIHSKFQTVPLPRFIKSVTVHDFEFGSIGPELELKDITDPLPDFYEEDAEDDEDGSDEEGASDDSDEYGPQFSDDEQQQTPGRRQRRRQPDNRSPRRTVEGGRRGMRHHHGHQAHHQHRHDLSGSSHHTITGLGVGGTTTPATAGAPGTRGGVPGGTSNLLHHFHSHLTPAGWSGTQTPLAAMAGGNLGGGSGQPGGPNGGGYFYQDHHYAYNNMNNMNIRQDNTTPPPNHSRNPSHSSSISVGDYYRDNLRLTPGGGIASSPPSNLPSLLQHPALREKHSVSTLAPTSAGGASRPPTRDGKQQQGPPHMSQMLGGSAIEDHDDSSEGGDNDMDRTLLLGQATGGPGGAPGPSPSPRFRREPRAEDMQAVFRIRYAGDVKLLLTADILLDYPMPSFVGIPVRLSITGLTFDGVGVLANIRKRVHFCFLSPEDALAAVGDDEAGEGDEDDDNVGDRRDEDYERPAPATPGRRPTTASAAAAQASPAPSHTLPRTKMGGLLQEVRVESEIGQRESGKQSLKNVGKVERFVLEQVRRIFEEEFVYPSFWTFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHM0</accession>
    <name>A0ABR3ZHM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EHD3</name>
        <name evidence="5" type="ORF">Sste5346_002770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="4">
        <location>
            <begin position="120"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="565" mass="61795" checksum="8AEF20D438071747" modified="2025-10-08" version="1">MLSRTLSRRAGPAASAAFAAAAASASPSPTIAARRTLTTLSSTAFSTTSSSLRASTLRCSFLLSSSMPLRAKILVPSARTMATTIPEPLDPATDVSDRLWEELPGDEPEDVLFTSLYGLRTIELNRPRKYNSLNASMIRKIGPRLLEWSKSDMANIVLLKGAGEKAFCAGGDVTALAEANARGLEGQKWSADYFALEYKLDHLIATYEKPCVAFMDGITMGGGVGLSIHAPFRIATERTVFAMPETNIGFFPDVGGSFFLPRLPGAVGTYLALTSERLTGANVFYAGIATHYLHSTSLAGLEARLAELRFNDYDSAEKRLTAINSTIEEFTTGLPIDQPILIGGNLRRAIDRCFSHDSVNDIVAALQAEATAPGEDEAAEATRTWATKTLKTLQHRSPTAVHVSLRQMRVGGRWSIAETFKREHLIAARFMREPDFTEGVSSLLIRKEKGRPQWKPSTLEDITDSGKVTEFYFTGERQADDPPELQLIRDRDYRESPYSALNIGLPSEAQVAALVNDGTKSQREVIHQLVGQYRGKQGVKEVVSEIIDRKTTRGKQGEAVWVDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIF6</accession>
    <name>A0ABR3ZIF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_002510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="658" mass="73232" checksum="AEE2EDF526C97FAC" modified="2025-10-08" version="1">MASKILMLVGAAVAFFVVATINGLRSNLRKARKTGLPYVIVPCSPYNGCWQLTHQVWVFLIKLFPKSMWEGWLFILLPDWGYNTGQEHFARLGDSFMVVAPFSINLTTQSPAAIHEIASRREHFPKATEHYSILEMFGRNILTTEGAVWRFHRKATSASFNEKNAAHTFAEAIHQSQGLVVKWIATAESNSPTITTIEKDTMTLALNIIGYVGFGLRFTWPGQPLPTDIHPRLLKYGSQEPPTGHTMTFAASVEGALHHIIMLLLTPTPLLNFLSLFWKTARSARHSYENYVQYMNEFLVDKVASAKEDAEKGVRAGDSGMDIMGQLVRGRYDDEAEKVKEKKTDKTKTTTTTPESTLTDDEIIGNAFIMLVAGHETTANSLHFALLKLATNPASQRALQADVDRLLGRDSDPTTWDYEASINGMLASMLGATMNETLRLMPPVVNLPKWVTPTSDQPLALHETGQTHILPAGCDIILSAITVQRHPKYWPATSPDDLDKFQPERWFETDAETTAAKAAKNEKSNIVGTDTEDYGGFSGPDTSAQLFRPVRGSFVPFSDGPRSCLGRRIAQVEMLAALAVLFQRYSIELAVDDWADNKTVEAMDDEARREVYSKAQERCRETLRGATTILTLKLHGMTSVPVRLVPRGQERFVHCVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIQ5</accession>
    <name>A0ABR3ZIQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL43</name>
        <name evidence="4" type="ORF">Sste5346_002497</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003058">
        <property type="entry name" value="PRK03976.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="92" mass="10121" checksum="56B6C073A466A6CD" modified="2025-10-08" version="1">MTKHTKKVGVTGRYGTRYGASLRKQIKKAEITQHAKYTCTFCAKNTVKRTSVGIWQCKACKKTIAGGAYIVSTPAAAATRSTLRRLREIAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA7</accession>
    <name>A0ABR3ZJA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wings apart-like protein C-terminal" evidence="3">
        <location>
            <begin position="496"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="989" mass="106104" checksum="C50D089BFF20CC86" modified="2025-10-08" version="1">MSTFNDLGQRPKKKLPSSYGNGKPGLKSRSQTSTPPVTGASESSQSGSQTPAKDIYDYDFVDDAPPPPKSVSKPRPLSSARPPLTTPRPSNKSTSSSSSGLAPSPMAAPTATPRPLPSIKKGNTARETLDAARGVKRKPSPNEATPVQRPSASIQRPSASVQRPSASIQRPSASAQRPSASLAASSHSLSRNAYSTQAKKIQRRSPSPGPTTVGASSPLYKQSRPISRVAESSSSRPVSSPLRQRVTKTPPREPSGTGLKSPLGIRSPSVSPRKTPASTFATASASKAARRPEPKSPHPMPIRPLDNLPSNSGDATPRKSPQRAAPVARDIYKPPPSTQRKRRRLIDTLASQIEEESSSDEETKPTEEPAAKDENDDDDSSDEDPILARYRNVRSTPSEGRGGYVDLDSLATASPSKASIAPSTPATITRRTTTRRPGVKFTYNLERTMLAEEPVELGGAQGSDLSLLESLLPEPESKPASFDFDEDMGGSSQGAIQSIHELRQAGANSRYADELVDILDRVGAPSAGKPSSARRSALLEMVQKLQEKSFLRHFRDQGAEMKLFRNIGKETDVISGYAIASIVITLLTNGAGSHRLMRELRQQKIKDLFLTLLATDADIVTYSKDRKANVSNHMRQQLTTLKETLKKLLAIWKPATVSPSQLSPRTVSLKALHMFAQQLQAASGGVSGLDEDDGALSAALTKELFAVISSALPSAYDDDGSTPEPPLLSSGLSSDADSVDLFLALSLLEMHSVSAMQSDISAEWTRNYLPIIASALGESLERHQKSSRRLNDLELLVLKLALNTANNNPDAARYYVDKGLLRQLAELSAGALAGVVRSAKTGEEFASDALNELLLMLGVMINFSENDAAAGETLEQGGGLAVFDRLGKAFLDGTAVASEADSEEKSQLNVAFAYLSILLGYLCLHDPIYQAFRQLSPSGNLNPLLESIRQFIILHDQIGKAENSEHGAEASHFTARLRALTQELDARAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKD8</accession>
    <name>A0ABR3ZKD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12841">
        <property type="entry name" value="TM_EphA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF32">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="58885" checksum="45EAA04A53BAE138" modified="2025-10-08" version="1">MSSDCISLQGSTRCPAFQSASISPSVASGQYDFLKFVSDRATFDSELAAYISTTFIQEQFQARIGCQGINLANTSEIYPRYLTSTICSAIVQSSISTCNLSAADSPPLCADTCAQYAESELYIVDDSALCANASSDAVKLIRSDFAICSSPDSALSSECVAGSTNEPDNCGYGNSTIGLCSYCASGSVNSTDTCCYNSNAESRCVGVVLPTIIPTVTFSATSSPTAPATSSAAAAPGTHHGLSGGAIAGIVIGALAGVALLAGLIFLAIVALRRRRTGSQNGSIFNQPSPARKGGIPQMSHAQHQVLPSSHGNQPFEVLPGGRIARMSALEGPGVDGDASPSPPGRGASAGAGAVAGAVAGYAVGRRRGDDHSSSDGYNDSPDSENRTGILRPPPTTMRRNGSLSSGSVLAGEDPQSPSSAGMSSPQAITSQQSEQLPFFKDYYSQDDIHPGDRVAVLWAYQPRAADEFTLERGDMLKVVGIWDDGWATGVMMDERADEWEARRQAQRDSGVSNTSGRGRDISPAVSGEIKAFPLVCVCLPEHWRKTIEGDSSTETASSAHPMHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKJ6</accession>
    <name>A0ABR3ZKJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3500 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_002399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489:SF1">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="47361" checksum="63C9608830FDBA02" modified="2025-10-08" version="1">MASSTPPSPYRKWLCTDAPQYVHLKTATAVSHTEHLFSNVPLVTKINKWWDELWKASFKGITSNGNVIPNLYPKTDHGIPIVEIVQAANGVIAAATEEERKRLLLAVDAPERRAWSNPEIYVHRFGVRLDESSENVQQAVLHVLKTTLSERGYKKAVNATLINHFLGTLHNAPAVLNRWSYNFMIFGQPSQTDDWSFSLYGHHLCLNIAILRGSQIVLTPTFTGAEPNVIDSGPWTGTRILVEEERLGLAFMQQLGPERQKAAQLFTDIDGPNFATEFAAIFPTCPSGCRWNPADQRQICGAFQDNRIVPYEGACLAGINKPLQDLLLKLVEEFVLYLPDEARRERLQQVASHMSETYFCWIGGFGDEDAFYYRIQSPVIICEFDHHSGVFLTNDKPQKFHIHTVVRSPNGGDYGHALRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKX6</accession>
    <name>A0ABR3ZKX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replication factor C (RF-C) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RFC5</name>
        <name evidence="3" type="ORF">Sste5346_001788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="352" mass="39951" checksum="5928A130BE287697" modified="2025-10-08" version="1">MALIVDKHRPRSLDALTYHPELTDRLRSLAQSGDFPHLLVYGPSGAGKKTRIVSTLKELYGPGVEKIKIDARVFQTTSNRKLEFNVVASVYHLEITPSDVGNYDRVVVQDLLKEVAQTQQVDQSAKQRFKVVVINEADHLTRDAQAALRRTMEKYSPNLRLILLATSTANIIAPIRSRTLLVRVAAPTHEEICTVLSASGKREGWPVLPALHQRIAESSGRNLRRALLMYEAVHAQNEKITDNTPIPPPDWEALIGHIAKEIMEEHSPARILQVRAKLYDLLTHCIPPTVILRTLTFKLVALIDDDLKPEVIRWSAFYEHRIKTGTKVIFHLEAFVAKFMRIFEMYLMSMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM61</accession>
    <name>A0ABR3ZM61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF4">
        <property type="entry name" value="CAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224461" description="Cell surface protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="26564" checksum="B434986A5FBE19B1" modified="2025-10-08" version="1">MFSKVFIIALASSPLVSAHGKIAAIQGDAGGNTTGIGIQGGVVPGAGPNSKTEVDTTVFNSVKAQSNGLGKTTGQGKNTLDMVSAAQDLSGGGDLPQVSSSGNGSLSGVYHIVTTDGAGPLKAVLDTTGTGNFADGTMMDVATQVPGTFGEISPNGKSVLRRALESMGVIAKRAANVNKDFPVAVSVPAGTTCTGTVNGQSNVCLAKIANSNPAGPFGGVVAFQMASDGTATAVGSGSADTTAAATASSATAVSAKADKAGKKAGKKARQFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMB5</accession>
    <name>A0ABR3ZMB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RFC checkpoint protein Rad17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rad17_2</name>
        <name evidence="10" type="ORF">Sste5346_001543</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057927">
        <property type="entry name" value="RAD24-like_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25812">
        <property type="entry name" value="RAD24_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Checkpoint protein RAD24-like helical bundle" evidence="9">
        <location>
            <begin position="625"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="236"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="780"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="847"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1015"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="847"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="865"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="899"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1091" mass="117034" checksum="C4489A1E8689A06C" modified="2025-10-08" version="1">MPPRRKRNVLDDSDSEDEKVREQRKTSLRNFFSPNKTISSTTGANSANSTNASPSKSTTIPTTPTTPTPTRRTRAVAANAKTPTKSPLKNAKSAAASVTSSPIAVSSPFGRILSSRVKDSNTKNGTSSSTNGNGNGGTSASGSPCPSPEKRRGSKGLKGQADERGKSADLVALFTKQAEKAQNSPPKKTVRLALDVDNMGSDPIVSDDDDVEEDDDNIAESSAVVSSYVGSRAQKRWKSGNTTLSSQQLPSSSLPSSAMAPPSSTISSSQRFKRPIRPTGANGTNSTTNDDDLRPWSERFAPTNLDELAVHKKKVADVRKWLEDVMHGRLRQRLLVLKGAAGTGKTTTVKLLAKDMNLDILEWRNPQGAYAAGATSMGFTSAAVQFDEFLNRGSKFSQLALDDNSSDSDDNTIRRNSNGNRNVKTDDKSTPRRRKIIVIEEFPNTFMRSSTGLTGFRNSILQYLAANTPSLAAYAQRRASFDPDTISPVIMIVSETLLTTTSASADSFTAHRLLGPEILRHPGTGLIEFNSIAPSLLAKALELIVQKEARKSGRRRTPGPLVLKRLGEVGDVRSAVASLEFFCVKGDDQGDWGAKVAFTKSRKGPKDAALTKGERETLEMVSQREASLGVFHAVGKVVYNKRDDLPPPPGTEEALAEMLPDYFAHHARPKRTLVAADTLIDEIGTDTHTFISALHENYALSCEQTGPRDPMSSVDYLNGCIEYLSESDLLCPTWDIFFGGRGSNRSNFGRDSGSHVLRQDEMAFQVAVRGLLFSLPSPVKRSSGAHYQRGDSTNGSGGVGSGAGGGGNQFKMFYPMSLKLWRSREEMEALVDVWSSKLLRGEVFQQGGSAASTQASTGGNRALSFRRPAPRFSSNSSSQAPSFSQSFGQSQRITAASDDTDRKVVIKKEDSDNSASGLGSISEKNEKPSTSTPPPLLSLGSSARKELLLERLPYMALIARSKRSSFGSMGMRDLEKVISFHGIGAAAAATGNDDADEDAADAACGVGPGNGGSFYTGDDAWATDRPTDDSQSSPRKPRRPLQANGRQAPLPPAANGRNGKAQANDIEDLDALPGLPMYNLVLSDDDIEDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMD7</accession>
    <name>A0ABR3ZMD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C45 hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047794">
        <property type="entry name" value="C45_proenzyme-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047801">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45_hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040521">
        <property type="entry name" value="C45_proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180:SF1">
        <property type="entry name" value="BETA-ALANYL-DOPAMINE_CARCININE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180">
        <property type="entry name" value="PEPTIDASE C45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C45 hydrolase" evidence="2">
        <location>
            <begin position="142"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="441" mass="49203" checksum="1286B6FC9CE4BD14" modified="2025-10-08" version="1">MTQIEESNPFTYQHVVCRGLPYERGVAHGQQAKTKVQENVQYYRRPGKLAHSAELMEAIIQHVYKPALEKYYPSGLQEMQGIADGAGVTLDDVVLLNSRYDLARLGDEPGSKPASDGEEKEKEEYSNECTSAVFHHNATTSGDMLTAQNWDMSARLWENDCIIYLEVHPDPSENKPSLFLVTEAGQLGRSGMNSAGLGVTANSLMSSDDYIPYPYVDAAGVRHDVEVKPMLPISMLRRMILESNHLAEAFTCAYNFPRHVSNNVTVSSAEGFGVCLEVTPDRIYKVYRTQADDRYLVHTNHFVHPGFLARSDVHCLYPGGSSWFRRDRFETNVRPAAQKGELSTKALITAFSDHISYPEALCVHPDRNPIDAVIGHLPGYPFRTNSATVACVIYNLTQKQITVCKGPPCQGQFQMFQLEGPAGNKRGSQHQKPDVERPEHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMW0</accession>
    <name>A0ABR3ZMW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470:SF1">
        <property type="entry name" value="CHORISMATE SYNTHASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="445"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="483" mass="51579" checksum="43F89A045016A447" modified="2025-10-08" version="1">MAIPWGTLKSLLIFFGPMLLPKAIGMYRGLKTQAAVRQRQSQQGAAATSRPLTFRSVLVLSLLTTAALAWLLSGGFILPASVSKALRLPAALRMPENVFVATESRLQAPTDVIFTRLASSRPYHTLTAADEALRLRLVSLESRLLYLQYGPDTIANCPFCGGTGVDSATNFSAANYLYYAMIDLIAAHLANLALIAVVTSPLLLLGRRGKSSGSAPQAAYAPIHSDFDGQGESAADHAYDIAATHIRRWRTPASLVTLCFAALDLYVVASYNRQANARATRLADLDFFYWSMRSYRAVACGGLLAALAAILYLAASGRHSSPRLGLLGVVLFGALPPPSPAHRVTAVTRGLTGTKSKLSAAAIVKNTALRDTDLRARTQAYWQREVMLVAEAMEEREVIEGVNDALQNRIDIQKIARDAEQYAQTVVPSLAVPSGGSRSGNINGQAAPAQSQSQPQPQVVVPRSTTPATGAAAVAGNKPTKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN07</accession>
    <name>A0ABR3ZN07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribosylnicotinamide kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NRK1</name>
        <name evidence="1" type="ORF">Sste5346_001950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02024">
        <property type="entry name" value="NRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="263" mass="29387" checksum="48BD87F164742E3F" modified="2025-10-08" version="1">MSSDDRKAVVVGISGCSSSGKTTLARLLRDIFPNTFILHEDDFYKNDKDIPISVDGLADWDCAEAISLPDMEQALVHIRTHGVLPPDLFSKEDQNSVGNCPVPDETIEAQKAKVKAWLQPGQPGSKLVSANNDGNTLRICFFDGFLLYSEATRASMEQIDVRLFLRVSHAKATQRREARDGYVTLEGFWKDPPGYVDKIVWPNYVEAHKWLFENGDVEGNPDKATLEAEGILTQLDKGIDVDMATTLEWAVDKLIRELEAKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNQ4</accession>
    <name>A0ABR3ZNQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="103"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="33787" checksum="8026A644153FD754" modified="2025-10-08" version="1">MKLLYPTSLELDIDSLRGFAVELCPYNVTVPFLVEHLDADIMVTWINTKDNLADAAARLHNLKWVQALAAGPNDVLEAGFDTSRVTITVGAGIHDDTVAEHTVGLLLDGARRFYEARDCQLQGKWPARLGGPYPRKGEFRTLRGARVLVWGFGGIAAKLTPLLKAFGAEVRGVARRPGVRAGVEILADTELPRLLPDTDALVMILPGSESTKDALNAERLALLPSHAWVVNVGRGISVDEDALADALHAGKLGGAALDVFKTEPLPADSRLWTTPNLLISPHAAGGRPDGCTNLIAENLRNFLADRPMKGVFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNX7</accession>
    <name>A0ABR3ZNX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytosolic Fe-S cluster assembly factor cfd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CFD1</name>
        <name evidence="10" type="ORF">Sste5346_001386</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03039">
        <property type="entry name" value="NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028600">
        <property type="entry name" value="NUBP2/Cfd1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="307" mass="32572" checksum="BED150BB5CCD7F5B" modified="2025-10-08" version="1">MSLTKVKHIVLVLSGKGGVGKSSVTTQLALSLSLAGHSVGVLDVDLTGPSIPRMFAIEDEKVTQAPGGWLPVTVHEANPEKGIGSLRVISLGFLLPKRGDAVVWRGPKKTAMVRQFLSDVFWGETDYLLIDTPPGTSDEHISLAETLLQNTTPDQMAGAVVVTTPQAVATADVRKELNFCTKTSIRVLGVVENMAGFVCPNCSECTDVFMRGGGKAMAEDFNVPYLGSVPLDPQFVVLVESGRTPVYPAGTQVQGADFVPPEASEGNGSSDADGRRRDLLVQKYRACSLEPIFRGITSEVTKAATTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP03</accession>
    <name>A0ABR3ZP03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="46"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="346" mass="37977" checksum="F2E162C656F6A627" modified="2025-10-08" version="1">MGAHQDGPGPESAEALHTTTISTVTDLLSETSIEDTNTSSEMLTTFTCFPNLPTELRLKIWHLSFVPRVIEVHRRKSHYADSASSVGQASLAKWQSWSANPAALAVSFEARSCALEHYSATIRLAVNTPCERAGEARLDLHRRLYIAPHADTLAMLGEFNVAQTVELMRHINNQTRGQTSDDVGRGLQRLALCASSIGHPGSGILLTIYGRNIFRDLDRLVLFLYDERVPPTAWTDGHCALVDCRDTYTFRRFQVGQGAELKSQGGKPGWMTVGHNPLEVLDLAFGREAEAASKLAAPVTKTTITHKSGARSIDDNALDKQLPQVTTIPLQPDRLDDNDRLIAAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP85</accession>
    <name>A0ABR3ZP85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047523047" evidence="1">
        <location>
            <begin position="26"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="154" mass="17005" checksum="7D723192825C719F" modified="2025-10-08" version="1">MKTTSILIGAFAAIATAAPASEVQARTSFDLSQLNNLNFQNQNFQYLNVVNSLDLQLLSQLGSVNNFNILGFQNLFQQSQFNLQSLLEFQQLQMVLQLAQLGLFNGFDLSSLNFNNLNFGLINGVSNFDVNSLIDQSLVPQITQVIQTAVIAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPB6</accession>
    <name>A0ABR3ZPB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001713</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1902007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF745">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="355"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="457"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="580"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="620"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="660"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="702"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="816"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="835" mass="90661" checksum="DDD10D66BC9DE85D" modified="2025-10-08" version="1">MPGLGSGNRSRKSARLSMDDFHNSAHGVRGAVLGEAGPSSERFNRQSLAINMSGCAVEDGDDDHEDDGETEGGLAAAGGPSSAPGKKAIKGMIRRASVSLHGFIQRRASFAGGKTALNTDDATNSTNSGSHFLPNRLLRSSHAHSQSQSSAQPQPQSHGQGKLPVRLQPANADARPTTSHNFSSWRRVRQVASFRHSRIFDSDFSAAAGPSESGSSNAYTNSMALETMEFPIREAGDLDDDNHRLVPTLSSSAPLPGGLSSMHGPPAFRSRPPVIPPNTGGAARAAAAAAFQTDILQMLQPKWLQQDEYGNDRESGIGIAVTSTDSDSADEANGQESYSTLCADGDAPQLDVAKVDFVGNLPMELAIMILLELDAAGLAAASRVSHSWSEAVKNQHIWRESFLREKTTTYATSGPVQPGVGLGVPPIRPSCDWRQIYRVKQELDRRWQEGKTRPVYLNGHSDSIYCLQFDEQKIITGSRDKTIRIWDMKTLACRLVIGPPEVVRDPKLLYDEDGQPAHYITTAYHTRSSNSMPAAVSFPMHHSASILCLQYDDRILVTGSSDGSCIVYSVKSGYRPIRRLQHHSAAVLDLCFDDRYIITCSKDVTICVWDRETGALLKQLRGHSGPVNAVQMRGNTIVSCSGDFRVKLWNIETGKAIREFTGHTKGLACSQFSEDGRFVASAGNDRVIRIWDANTGECVREMKAHESLVRSLHIDSVSGRLVSASYDRDIKVFDMETGQQLLDFPQWHQSWVLSAKSDYRRIISTGQDPKILVMDFGAGIDGIDKLETADANAAIRTPICAADDTTAATTEHMDWTPSAPDASAPQVTVEAATPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQE4</accession>
    <name>A0ABR3ZQE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001448</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="51"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="404" mass="42829" checksum="1B4755BD6960AB3E" modified="2025-10-08" version="1">MSTAPGNQDHPGGSAPTALKAHPPEEPPADNAEVHPAGEPATPNPNASTFVLVTGGQGFIASRLILQLLTAGYTVRTTVNNLAQEAKVRKGLAAALTAAGAVDADADCHLRRLRFFEADLASDNGWSDAMKGCTYVHHDMTDDDAPKESVLRVLGAAHEAVIDRVVLTSSFATIGYGHPPDANRVFTENDWSIDNSSLPACHRSLLQAERAAWEYVQRLPVGSGRHGNKMQLVVLNPVGIYGPVLSGLQSSSTPSAIARLLDGTWSALPDLHLGMVDVRDLADLHVLAMTASDESSSGQRFLAASDGRPTSLSGIALAIRKERPQLAKERKVPSVSVPNWMSKAASLVSGGGSKELPPMLGPVRNTNNARARDQLGWRPRPSYETIMDTVDSLVAVEEAAAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQF1</accession>
    <name>A0ABR3ZQF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="44929" checksum="AF9A6C5499DB9B6F" modified="2025-10-08" version="1">MATIARQPFAPLDGSRLQALTSTKNRQNAVQSPASKRKAPTWTETEDTENVDPHLSAKRSKGTDGSAPGGIMLKKASSPFTLTKANINLTSVANIFDAKPSPLSTSSSPRAMLKPRAPSTKSSAMKINTSPIRSSPISLSSASLSSSLSGRSPIRASRRGGLLTNKRRAASGLSRSSPTNAGASNFGSAAPFSLDAALKGTFSSFDVRLATAALPTLDSSLLDDASGMSASWFFDIHEDTPEQEMTNLLQHSTCVLDISSDEESEQKARRERAEGRDKENIPPPNDVSQTSVAHTTALAAAPASDEMSVDKARNPLSQLNAADFYADGCDEASVVLVEAEAEEEEQAAVAQSIDAVVEAAAEKEVEAVAEAAVMPVEATESTKTNVEDIMTNREVPACEAALLEPIDGTGESFQLWESGSQKDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQH1</accession>
    <name>A0ABR3ZQH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000858</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="219"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="46"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="578"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="600" mass="64816" checksum="0DE7952AC76512F0" modified="2025-10-08" version="1">MNPPDNNTEVHEAAVDAPAGEDLGIQTAADTGLTVSKPIQYERWFIWISFALAIYVMGLSSMTLAVYLNTAAAVFDSLVQYTTLGTVQDIIYGVGNVVFAKLADGVGRPFVFSFSIASWAVGTIILAASNNIATMSAGMIFYSFGNTGLILARNLLLADLVPAHWRCTANNLMLAPFIINFGVASKITAALVPDNWRWGIGMFAILVPVTMAPITFYLYRMAYRAERLLRDTEAAPRRRSFRQIARAVYEFDIPGQLLLLFGFGLLLLPLTIADQAPKGYATGYIIAMFVLGAVCLIAFPFVEKFSPVPSINFSRLRRLGGGWDVVVATAISMADALSVMIAYTPSYNWVRITFDYSVQNATYYLYASSLAVVIFGIAGGLIATYTRRYKWLAVFGAGMRLMALGLMYLYRGPECTTAQIIVPQVLQGIGTAVMTANLQVAAQISVSHADVAMVTGIFLMWGGIADGAGSAIVGAIQQELLPELTSSLAGIANSTVIEDIYASGPLALVDIYPLGDPVRTASIDAWIKNTRQVLAAALAIAGVNFILTFFLKDRVLPDTQNAVTDEATGLPVHFPSQQSDKVAEMSRVDNENDQTTEIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQM2</accession>
    <name>A0ABR3ZQM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="70" mass="8010" checksum="31E9AE756A79BDF8" modified="2025-10-08" version="1">MCFDYITTVIFKGCGHSRPEPYDYYYCPNTEATGIPCPTRLEMDDEICHEVEGILLSLRPKPKPKAAQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRM0</accession>
    <name>A0ABR3ZRM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22952">
        <property type="entry name" value="ART10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="888"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="899" mass="98834" checksum="618832B0F02DAF5D" modified="2025-10-08" version="1">MSVYIHLIEQPEYYTNLDIIHGEVKFFLSKPEAIGAVVVKLEGESSTSLTVPPVEDEEGWTYKNETLHDLDPSRKSGGLITRPAPGTVMQENHKILYQVAQVHPLKSEEPLTSNILPAGQHTFPFRFKVPFNNVCSDPIALSRTGGMVDVDGNVESPSGGPHRYGVGNNGIRIMDGTKQLSYNHVKQTLPPSFAGYLSTTETTEIRYFVKATVQRPGMFRGNWRNTVGFKFLPIEPIRPPPSTREMFARRPFTFRDRIPPSDVTPLRPPKKKNSFFRNNSSSTLSLPDSQAGSNVSPTSPSSSLSTSPRTQKFPIALGCRDGVTPSIQLIALLPFPAILTCNEPLPLRIVARKLEASREQVYLTSLDIRLIGTTRVKGQDLEQTKTATWMIMTRLGLSIPVCDPDAPVDTEMELPDDIWRNKALPNTVMPSFVTCNISREYQLEVRAGLCWSVLPMDTGTPLASETSSNGQSSAGQLSKKEMKEQMKEQKKEQKAAMKAMKVMKPRPAHLLPQTIILPLTFHAVQVYSGIKPNQMLVDAVTRHRQRMSMRQQQMRREGRPSLPDTRIHQQFQRQLHQNPYPNLDQNPQSLPTRQLSRATTFPAESPYTRHQSLSQPVQQQAPLPHMPQQPPLQQQQQVHLPQEYDQPIFELSSEPAPAVPLRPDGSAYVPPPSPSTVTPPAAATSSVPPPSVPGAVEVSGLPVIRRRPVPQQFVAQQREEQQHRQTREKFPSGEDPSAMQQSPIGRMHGSVHWHGPNQPYHMHQQQTFVNPLYPPQLRPGEDPMATPTAHSPSSGSAITPTSTGGASGGIVAQNGEVLVTYNGVVSSMAPAVASAINAFAFADGDTASIYQEPPPSYDEAMADPATAMGFSDNDTGGAAMRPAFSGEANANTMSASAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRR8</accession>
    <name>A0ABR3ZRR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARC15</name>
        <name evidence="6" type="ORF">Sste5346_000011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="209" mass="22313" checksum="7047F531768F9DB9" modified="2025-10-08" version="1">MSIIQQHSNASLGDAWRTINIDALEEDSPANFDIATLRPPVPEITEPEVRQLAGQVRQLLRGGDNDGALRGCLEMPVYVGSDGAKEAALQTILEVLQSIKASDMSPLLKRLYATENGSELLDVLMKYLYKGMATLKGSGSSTPHTPTRTPTSGFNTIGSLGSSKGFLPGQGGGDSTGAAMSVLLSWHEKVVEVAGLGSIQRTMTDWRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRY5</accession>
    <name>A0ABR3ZRY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Sste5346_000833</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01044">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="152"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="549"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="723"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="549"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="585"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="738"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="924" mass="98132" checksum="D5A86FCA393CA3D9" modified="2025-10-08" version="1">MAAVTATPSPNPTHKRNVPRRRRGGAVGRRRRIGEEDVSEDGVQSAVELNNDDSLTEGSIASDERDAVNDSDTSNNVDEASPTILVHSKGPNARTGGGQGNGRGNGTTGGSAPRTPALAVDGSSDAAAAAKPSTPSASPSQQQSSAPPVKQAQPAIVSSSSAQPPRRETAYDRQRREHDLYKQRRDEDPSFVPNRGAFFMHDHRGAGPAANGFRPFGRPGRGGRGRGGFGGSFSPMHNQFQNQADPIANQPWAHDMHEVVTQPNASRLSIPRRQNYDAANQYAANQYAASHAASQYAGSQYAASQYAGSQYAGSQYAGSQYGGSQFGGSRAPPPVAVIPTCPPSSTPINRSMSVEKTLGTVTVRVFFPPMKEPTFFEKFKAMQYTKLPDHRPPLRRDKAVVIDLPDHPKKQIFPAVDRSFIFIPRALRPNQQRTRGGRTRSVMGSVSGFSRRTSVFGGSYYNGSMYSPSVALSRRSSIAQDAARDFIISPAGSVISRPPMTMENAARPVVRLPPSVGPPVQPAGMVPVMPVAAMPGPMAVPPVQPAAIPMPPYPQQQPPYGPGPAAPAFNPQPNQWPSQGPPPSHSSSSQQPEHSQSSQAAQPAQPAQESQPSQPPQLSQSSEPSQTSQQSQPSQPSQPSQSHQPSETSSLSSVPPPQNHPLPQKPTFQENRPSHNLPMHQPRPQKAVSVENIEAPAAAAIGAMQPQTQQPYSMAFHQQVPIPMASGYPPAESHSRHPSYQSHTTGTPLSQIPERAIHAAPFQPNMPGQQQMAYLQHNNMGTPSGQAYYGGAPGGYVMQPAPQQGYYYPTPPSYPSTMASTAGVPTFIPGGTPQGPASAYGQPGQVDASGAANSGPRNMVAQEVNGMVYYVDASQMPSGPTYPGYGQAPAQQGGYMSGIGGMVTPVPADGYYYGGQPGMMYYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS70</accession>
    <name>A0ABR3ZS70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenylyl cyclase-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SRV2</name>
        <name evidence="5" type="ORF">Sste5346_000924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013992">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018106">
        <property type="entry name" value="CAP_CS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01213">
        <property type="entry name" value="CAP_N-CM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01088">
        <property type="entry name" value="CAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="4">
        <location>
            <begin position="396"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="340"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="568" mass="59785" checksum="96EC0F66D0C7EF03" modified="2025-10-08" version="1">MATNNMNNLTTLIKRLEAATARLEDIASSTIELPQAVPGLQQSIASPATGESSVSTPSAATTAAVAAPKAAPTTTPAEPLPEIIEEFDVFLNGAVAKFVELSNKRGGLVAEQAAKVQDGFHAQRTFLLISTKAKKPDLTGAEMSVYQDLLKPINEALMAVSAVKDNNRGATDFNQLSAVSEGIMVLAWVTVSGRPFKMVEESLGAAQFFGNRVLKEYKEKDPQQVEWVQGFYQVFRDLADYTKEYFQNGIQWNPKGKPAAEAAKEVAASATGASSSARAAPPAPPAPSAGGPPPPPPPPPPGPPPVLQIKEQPAAELNGAGAGTAHGAVFSEINKGSDVTKGLRKVDKSQMTHKNPALRASSTVPGGSAPAAGGQRGKSPVPGKKPKPESMRVKKPAKKELDGNKWTIENYDKEAAAALGGPIEIEASINQSILISKCSNATVIVRGKGNAVTIENTERLSLVVETLVSSVDVVKSKNFALQVLGTIPTVMLDQVDGAQVYLSKESTSTQVFMSKTEGVNLNIVTPSDQLGADEEEGDYKEVPLPSQICSYYDAEKGELVSQIVSHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSF1</accession>
    <name>A0ABR3ZSF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PHO5_1</name>
        <name evidence="6" type="ORF">Sste5346_000943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF18">
        <property type="entry name" value="ACID PHOSPHATASE PHO11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045207523" description="3-phytase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1903030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="481" mass="53034" checksum="E1E6530EAAE8ECAE" modified="2025-10-08" version="1">MSSTSLLALGLAFISSVSAGRHGYPQFGEKQFSQSFLDGYNLLKFTSSLGPYSDRVSYGVDRNTPAGCQVDQVFLLMRHGERYPDYSGFGSNYETVLAKMAATQKNDSSSWKGDLAFLNDWTYYVDDPAMYSQESYSGAYAGLADAYSRGTDYRLRYGHLWDKKSVVPIFSSGYERVIETARYFGQGFFGYNYSTSAAVNIISESATQGANSLTPSCPADPTYVSCLVGSFSRTMPELGVAAARFNSQNPGLNLTALDVSYLMQMAAFELNVRAYTPWAEAFTLDEWVAYGYIWDLMYYYCVGPGSDYQIAVGQVYTNATRVLMEAGPKSGSMFWSFVHDANITPVVAALGLDIPANPLPNDTIPFPNQYRVADIVPMGGHLTLERMTCNATVKSTAGIYVRAVINEAVVPFNACQNGPGYSCPLANYSSLIVDAAPRFDEKCNTSSSYPQYLDFFWNYNTSTQYNFQDGPIGYQLTDTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSK6</accession>
    <name>A0ABR3ZSK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Orc1-like AAA ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_000290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048866">
        <property type="entry name" value="ORC5_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21639">
        <property type="entry name" value="ORC5_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="ORC5 lid" evidence="10">
        <location>
            <begin position="240"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="9">
        <location>
            <begin position="349"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="55164" checksum="AF33D0D7A54CBAC0" modified="2025-10-08" version="1">MRSISQVEPAEAQSAVRLLQSFPGREQQIKTLSTLIDPSLAPCGNIVVHGTEASGKSAVTAGVLQMLSLIASPDAAGDASSDAGARENSLDYAIVDSNKCVTARHLFERTVAKVSDAVRYLGPKARRCETLSQLTVELSNMLKYGDHPEGYRFVLVFDAIDRQRDAPPTLLPGLARISEVIPNITVIFIVTFPSPTMLRTSFVPHIQFGNYSKAEFVEILSRSPPPTLEDATDEETSELWTRLCTAVHDSLTRTAGRTLPAFQEACMALWPKFTAPILAGTHGPREFSKLLIAARSHFQDESLLDPGFVVAAAPHVHSQSQPQTQLATGDAADAPAENPLAARHLATLLPATARLFLLCAYLASHNATRHDMTLFSTYYHGKKKRRGGMGGGAGRTGPKSKHRKIARKLLGAHSFTLERMMAIFVAVRSEWTRAPPVSATGRNSAAALMDGDRNTAIATLASLRLVVRVSGAASDPIDRAGKWRVNVGWEVVRSLGRSMGIEMEDWLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTP1</accession>
    <name>A0ABR3ZTP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39132" checksum="7CCDD702CFF6C7ED" modified="2025-10-08" version="1">MAPQSSILITGTNGTLGAKIVATITGNAANAEKYHGLYTVRNIDTASTLKSVIAKAPKTHDYDVLELDLDRLQSVRYLADKIRTRIATGEIPPIRAIIWNAGFQEQSTQTFTEDGFDTTFQANYLSHWLLTMLLLGSMDKEHGRIVVVGSWSHDPADKRNEVGGPDYFSDDKWKTLFNGTRSLAEGTFSPPDSDPKGMAGMRRYGAAKLCEIMMIREMQERFDKDPVLFNISILGVDPGGMATTLLRRGNFWFAHPIASKFITAPLSYAWSKFQANSLMRPVSKSARDVLRAALESGPAPLSEYPKGLYFNGDAPMLQSMEARDPVKTNVLWRDSIMLTGLKEDETALKMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU14</accession>
    <name>A0ABR3ZU14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="318"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="479"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="354"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="668"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="960"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1098"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="702"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="763"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="834"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="846"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="882"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="969"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1099"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1139"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1188"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1247"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1302" mass="141385" checksum="E4D30F765BF0DCA6" modified="2025-10-08" version="1">MLFLHQIGSVKIGEIVRYNITYTPAYDRILPAPEYLYLKVRNTSNSALRAAFVHGPYTLYVDAYPAHFNPNEKFAYPRKYGVPEFEPMLKAGGTWTCRLLVPEHVRHEAGTGSHTSEDGGPPSVSWIINISSQVIFSTSAAVHFEVLLARDPKSLESGGGITAGMPVLLGGSGNGGDGNGSGKGGGGNQGQVLQPGKVSDYQRGRDGRHPDQPRGVFSRAISMRLEDTAALWNKPELPGWGKPPSSMRIRTDESGVTVEAVSGGALTKKQQQQQNQQHENQEEQQHETQKKLEQGHASKSQAKQQARDTIPAPKPGQKKKVHLVILTHGLHSNLGGDMLYIKESIDVAVHQAKIDRKARKEKERAARAEERKKAGISDDDAEEEEDDEDEEDVIVRGYPGNATRTERGIKYLGKRLARYILSMTYPDQPFLPSSKKVNEKTAVVLAGGNPNDVPADRGHASHKHSTIKNAPAESMREYQFTKISFIAHSLGGLVQTYAVAYIQKHSPQFFDLIEPINFIGMASPFLGLNHENPMYVKFALDFGLVGRTGQDLGLTWRAPTIARSGWSSLVGNLSDNAHKKVLGEPQPESKPLLRILPTGPAHTALKKFRNRTVYSNVVNDGIVPLRTSCLLFLDWQGLDRVEKARREAGLVETVVGFGWAELVGNNATTPRHEKWDPNDYVDEDDEDEDEDGEKKKADTSAPGDNTSGTNTPNPEGHNQHEVPQPSKNATQDDDRQSLRAVAVSSSFDQDERPQLASPPLPSPDASKLTTASTNNTNPFSNFFSNLFKSNSNTEDPTHSPGGTTPRRGSGASGGASSSNPRSPSLSQHPHKSPSHSSSMSNKQSKIYQRSQTLRSSDWEAATPMSATSSKSRVTTGQELDGESSNGGSASGMSAPPRTSFFESATDIINPKMPSVEFLIDPSKRPRAIFHDRIYHPSDIPAPPLKRRATGNLALRRLSFQQRSKTSLTSASGGNSANNSASNSKSRSSSPYQERTPATPTATGGPPHMDSGLSAQDYDDMANTNPDRDPDEVIDTSSIKVEEKIARAYHRNLSWRKVLVKLEPDAHNNMVVRRMFANAFGWPVVKHMVDAHFSDSAAARMRDEDEDNKERARPLHEAPDEHGAETRTQKHDHESGQKDDADDGADDEENDDNEDIDSGDAREAEDQAMDLPETPMGGHSGLPPRTKSKSSTSLASDGQNDNVAWTDKDWNDSGDESDSPGGSTAAAEDDPLAYGASKDQKPPKSPLASSTTGVSVTATGGTTTGPQSPLSNPLSSPAGDSLLPELSISAPGEGNNRKRIDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUC4</accession>
    <name>A0ABR3ZUC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">rRNA (Cytosine-C5-)-methyltransferase nop2</fullName>
            <ecNumber evidence="12">2.1.1.310</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NOP2</name>
        <name evidence="12" type="ORF">Sste5346_000270</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.310" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023273">
        <property type="entry name" value="RCMT_NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054728">
        <property type="entry name" value="RsmB-like_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF30">
        <property type="entry name" value="28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22458">
        <property type="entry name" value="RsmF-B_ferredox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02012">
        <property type="entry name" value="RCMTNOP2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="11">
        <location>
            <begin position="315"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="611"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="620"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="683"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="714"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="745"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="532"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="407"/>
            <end position="413"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="757" mass="81547" checksum="29D54260B57EDEBD" modified="2025-10-08" version="1">MGVGRRIGKKQGAPEPLSEEHFARLKRKAGLPVDSPAGNADSPSSKRRRGNNNPKDEKPAKKAATNGSKNGVKKNGTAAAPAAAAPKKSTKAAAPAPKKKQLLDPDSSDDDDEMDIGSDEGAGGALLGEDSDDEAVLLGDDFLGSDLDDDEVLDSDIEDDGKGGFVFSDDEDESDAEEKLTAANIEGLSRKLDKKQAREDAAAEAELKESALQTNIVGTNMFDESEDEEGGEDGLPGAGSGKAKTNLAPDLQLLRTRISETIQVLEDMPRLAAKDRSRTEYVGQLIKDICAYYGYSEYLADKLFHLFPPREAFAFFEANETPRPVVLRTNTLKTHRRELAQSLINRGVTLEPVGKWSKVGLQVFESNVPLGATPEYLAGHYILQAASSFLPVMALAPQEHERVLDMAAAPGGKTTHLAALMKNTGVVFANDPSKARSKGLIGNIHRLGARNVIVCNYDARDFPRVMGGFDRVLLDAPCSGTGVIAKDASVKTNKTEKDFMQLSHIQKQLLLSAIDSVNHASKTGGYLVYSTCSVAVEENEAVVNYALKRRPNVRLVETGLPFGKEGFTSFMGKSFDASIKHTRRFYPHHQNVDGFFVAKFKKFAPTPANAVRAEGGSTKAAATTNSDVENNGDDSDATRASDKAPISETDDDDESKDDGFGGFDDDEDSKYMDRARKNAMRRRGLDPHMLDRKPAGKKEKKAADEKTAEEAAKESATSDSDAAPAVEKKEKKEKAAAATTQKPAKAQKGKPQGKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUG5</accession>
    <name>A0ABR3ZUG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039970">
        <property type="entry name" value="TF_Grauzone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225:SF2">
        <property type="entry name" value="AT09679P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="385" mass="43505" checksum="E6A6BB05DB596F05" modified="2025-10-08" version="1">MIPNAHQQQEQQGISQQELSRQLVESGLSERDAMLVAAAQKPFKISIKLAGQNHMCNECNAGFKDVDSLRNHVRKQHTRPFHCVFNWAGCESTFASKNEWKRHVMSQHILLHYWVCQVELCSKVVNKAPGAAHSSFSLPNGAIFNRKDLFTQHLRRMHTPTHVRKLMKQAKMAHKTANHPAIMEWENRMKDLQEDGRKPRCQLPDFMICPSPGCGVEFHGQGAWDDRMEHVARHLEGAAAGRETLVSFGGKSDPTLTNWATRPMVGIAKRVGPDSWQLDNPLRPEIREWTGNDDDMAVDNPPRTEAGEQVLPSSEKPLPEEVVHDKEETEQRHDSPSDEKSSRERSKSVIEVAIPHSPIRDDSSEHGPEQNSDPEQTTEKGTAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUU1</accession>
    <name>A0ABR3ZUU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="5">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000659</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081:SF8">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="6">
        <location>
            <begin position="80"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="215" mass="23591" checksum="1E14F6EB3AA601A8" modified="2025-10-08" version="1">MLSQRFTTILRTVSAVSARSVASSRSVLRHLPLPPPPPPSVTSRTILRSMPSIPFLGSFFSSSSSATKKEDMSFPDQRSDSEWRAVLNPEQFRVLREQGTERPFTGEYDKHFAEAGVYRCAGCQAPLYKATHKFKSGCGWPAYFDSLPGAVKRNVDNSLGMERTEIVCANCGGHLGHVFKGEGHPTPTDERHCVNSISIKFTPEDEAAAAKDSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH83</accession>
    <name>A0ABR3YH83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF6">
        <property type="entry name" value="ISOCHORISMATASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="25"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="212" mass="23188" checksum="A5EFDC7140734DBE" modified="2025-10-08" version="1">MLEALKHTSTHALRLDDMAGTQTHTALFVIDIQDELARDPATRIPHADRVVQAGERILQSARQAIQNAKANTNTETPSIIIFVQHEETDGTLLRGSEAWQLVLPPKSNTTTELLVAKATRDTFESNPDLAQRLRDLGIGRIVAFGIQSECCVLSTCRGALAAGFDVALLSGAHSTYDVDGKTAKEIERGVETELQSKGAHIHPWEDVVKSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL3</accession>
    <name>A0ABR3YHL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large subunit ribosomal protein L14e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000117">
        <property type="protein sequence ID" value="KAL1887510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein eL14" evidence="5">
        <location>
            <begin position="59"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16213" checksum="15D2DBACFF9836C3" modified="2025-10-08" version="1">MGDATIIGSKWRLVEVGRVVLLQSGPSAGRLAAIVEIIDHKRVLVDGPASDANPGGVARQAVALADVLLTAIVVEKLPRAARSGAVKAAWEKSEVDSKWTATNWYKKRVQNERRKALTDFDRFKVLRLKKQRRFEERKALAKVKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI87</accession>
    <name>A0ABR3YI87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="333" mass="35296" checksum="2AFC3139AB31F72F" modified="2025-10-08" version="1">MGVSATASYADPRRERQAQEQAAMAESPQIGPDIIANNLDDTNAYNALNIHNVGKIGGANVAGPANDSEISPTSSGQTGSNEIRIVIQPARLSRSPNVAGSSSSRALQRQWPMPPGHLGPAVSMFMEDTGTATNTRANTVAETDESNGDNHEPAAYDPTAWSTASEFGGSVTPETQQQYLQYQRYVRQEEERERLQSAQGLQSMQSLQSFHPGGLQPPPSLPLPQPPQLPPSGLSTRRASGVPSSAVLGAGQQWGSAYGFYGDDGNNNNGGGGASSRDRSQRSARSNRSTDIMPSRPSDDRQDSSGGSDNTQTGTSSRRNRFNFGSIGYGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI91</accession>
    <name>A0ABR3YI91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rab GTPase ypt7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YPT7</name>
        <name evidence="6" type="ORF">Sste5346_010028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01862">
        <property type="entry name" value="Rab7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="217" mass="24727" checksum="EB47FBEAC8C2BC6D" modified="2025-10-08" version="1">MLKTSERKHEADSLTILQVNKKFSASYKATIGADFLTREVPVNDQQVTMQLWDTAGQERFQSLGVAFYRGADCCVLVFDVNNAKSFEAIEGWRDEFLVQASPRDPDNFPFVVLGNKIDVEESKRVVRTTLFYNDQGPRERTGLIAVYHQISTKRAMTFCQAHDIPYFETSAKEAINVEQAFEVIAKNALQQESEEFPGEYQDPINIHIENDRDSCPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIA0</accession>
    <name>A0ABR3YIA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000142">
        <property type="protein sequence ID" value="KAL1887149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF12">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="266" mass="28289" checksum="494E571F937ED33E" modified="2025-10-08" version="1">MSGLVQGTAFITGAASGIGQYTALAFARNGITNLALADINLEALEASSKELREKYPNVNVLNLQVDVQSGEQVKATVAAVVAKFGRLDIAVNNAGIGGSGKPTHEVDEEEWRRVINIDLDGVWRCQKEELAVMVKQEDLGVRDGRGRIINTASMYGIVAPGSLMSQTAYAAAKHGVVGLTKGDGNTYGPHNIRVNCICPGYVETPLLLRSMDTDPDSPLGIDIARTPLKRMCAMEEIADAITFLASRMSSFMQGAALISDGGFTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ0</accession>
    <name>A0ABR3YIQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009826</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000102">
        <property type="protein sequence ID" value="KAL1888029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="100"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="757" mass="82590" checksum="A0A56D8A9A1BE704" modified="2025-10-08" version="1">MERTRAARSAKWGEACAPCASAKTRCIRNREEPGASCDRCQSLGKDCFGQVQKPRKKRQARPSRTAQLEERLNNLIQAMSSSGSARSDIAAAAAILSASSTTGTSGTTGTTGTTATTVSDTTNTSQRQSSPPSSPSSPEPDHDDTGFGLPQRFGAPPISPHCTCRVPVSRADLVPVESDEVLLNIFINQLSAKFPFVIVPPGTTVQQMIDTRPFLMKVIRMVSSVRYLRSMWGQSRAVIKHISEAMLVRSERSMDLLQGIIVFLGFYHYFCMSHAHFNNLAHLALSLVGDMGLSAPPRPANHREGAEGTAGGQSRIVPRHARQVVTHTSDEAPAQRTNEERRALLGVWYINSNAGSIVKQLGGTRYTKYIDQCVNELEQAAEYKSDQLVVELIRVQNLAETIFHFHNRDQLLDDLPGVPRLSPIVYLEALQAELDRLRAALPQHLRSNPLLTCHYNSARLSLFVPLLAEECYLADASLGPMDLFTRFTEALKTWFADWLTIPVCSYFYLPQSASSMLVHASRHLVQWARLAGPSAVRLSSTAANCCPLLASTASLSSGSTPSTPSRSSPSSEPYVPRPRFPTFMGIPSCPTLDVPKRPTAVSDAVTVAAQDTIDMLRAAIYAEPDLRLDILGIAAALVARFESAKVEITAAQGGVWKNDTWDAAGDQLRMKRFKIEEWVESATAAGVDENVPLNFGPPPGEQPVSDINNINNSTTNNNWKWPTDLADGGANLDFGTLLDSNNDWNTDWNAQGMSLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK42</accession>
    <name>A0ABR3YK42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="46"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="376" mass="41163" checksum="17B3876D5B37037A" modified="2025-10-08" version="1">MLAHRPDFFSAVSVILVTLDSSTTAGLATILDQASIAQPAPPVDRPILKIQDIPDKGLGIVAGQAIPRGTILFRDQARILADVRFPQHVRRAQGQTLLHKAAGRLPEPDDVRNLSRSIKAKPGEARGLLEENVLSTNSFAATVDGISYMALFPEIARINHACNPTALTRFNDKDLTQQVIAFRDIKPGEEITISYTDFGLTHDARQETLKRRWGFECTCDLCSGGPDATAASDARRQRVTALRAEVVAHLQKGAFDTAIAAYEGELLRLVRTEHLAEHMGEHFEVLARLHLAAGNRTAAVSYAQQALAELETFEGVSGVRAGAVSESSSGSIQELREFVKALHGQEERKKKRKQKKPKGEKKQVKKQKTAKKNGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKZ3</accession>
    <name>A0ABR3YKZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1888999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF177">
        <property type="entry name" value="PROTEIN YOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="393" mass="41655" checksum="8314AC66CA381BDB" modified="2025-10-08" version="1">MFDILPKALASIASFLFPLFASYKALNTADPAQLTPWLMYWVVLACVVLVESWTDWILVWIPFYHYFRLFFLLYLVLPQTQGARVLYQQYIHPWITQHEAQIDEFIGSAHARMRSAGMHYLKQAIAYLRTALGLPAAEESPSAASAASNSGGISGQSYTQALLARFTLPSARWPGGAMGSAAAAHAGNTSGPAVPSSGSDFYGMLATAVGALGTATGAAGGVAAGAAASAFSRGLGLGNNDSDNMSASGTLVPPHVREADRASFLATQRDRLRTLLSALEREAAQLENEDEVLSKTSPLSRPMSSASGLSKSRSEADFEKIDAESGTEEEKPVRQRRQGASGLNESTHPSAGGRTTSGSWMPWGWRTGGGSEDSTHDAADDANTAGKSSSVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKZ5</accession>
    <name>A0ABR3YKZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="239"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="770" mass="85886" checksum="66F28DA4040BBE59" modified="2025-10-08" version="1">MDVVAETREEEVGVPAGTDLCDLCSKRFGEPSSHYKCDCHRSGAHFHLGRVDKYVDVTTNPPTRPKSTCPGCRLFNTIVTNMFAMIRRNDHSIQPAIVSTGVTSELKLLEDMVTSGADKTLKIEMRAAARAVTVKVDVLPGIAGTIIRLAGSPEKERIHGLRVREKQRVHGLHIPAKIDMDRTRRWLTTCQEGHASCRQREVTAPPQGQTPADVDSTSFIRLINVQTRQIVPGTLNSEFVALSYVWGQNTQPLLTRARLTGYMAPGGLATAELPMTISDAMEFVNDLGLRYLWVDSLCIIQDDDVDKQKQLPQMAALYEAAELVIVAAAGRDASAGLVGYKTDRQPSQAVETIDGLTYITYQSGLHDVLRWTHWDRRGWTYQEAFQARRAVVMADTLTYWSCRDTLWQEDLDNDEGSGVRLRKDSNALWRYTPDGQRTLGCTPNTYFTSVEHFCLRSLRDGSDALWAYWGVLAHQSPRFPPNGYIWGHPYGSISDSLLWRTGHFCLSEHRRRQLKTFHGIPIKDGSILKAPFPSWSWLSVDTAVDFLDTCGSSIVSAVKWGVPITLWNPASAELYLEYLRRVGVDGVDKVKELLVKQHGHLKPAPTPGQPFAMDYGLLCFTAKVAQLTLSRQYKHTNDDKCPCRLGPDRGKDKSHMYAAVRHGDKEIGGVVVPLSLFNGDDIQDVAVEVVHLSSNALPRTSTDDLCKVQPASGCREVQHVRGCQHIESHNLMVVAWEHGVAHRQALFALNKDAWEAISSEKKVTKRVILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL07</accession>
    <name>A0ABR3YL07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1889014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="372" mass="41598" checksum="A9444654F6BCE04C" modified="2025-10-08" version="1">MSDELMDVNATTSPPVTVRNFAMPRLRRCPFDIDTIDWRRARKLGAGADGCVYRVYFGDRGPFALKLFWIPDAVVEFPTYSAVHRECQNAALLQMLRASVDQTATTGSSSEKLDVTGPPLVHPNPMDFLTASDNLFSFADEVRRARQKQPPPPELQLVPVTSMPRFAKCHGWLPCNVHELMAKMPRHMRSHGFHVDRKTYRTFDQTRTDFIGIVYEYIPSHDGDETDDGGGTKDDNGGNDSTGEELESCKKSTAPPAARRYNTRSSTIQAVHDANGDNEQPRQARPAAIAASNEDTKDTKDTEDAMHRNRVSAVADFLWLAGFKFCSQPLARNWKNGVLVDHSEIIGPYSSGWQRGPRNTKWSVERLLTPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLC0</accession>
    <name>A0ABR3YLC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF2">
        <property type="entry name" value="DUF1446 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11420)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="517"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="70367" checksum="78763785B4873DE5" modified="2025-10-08" version="1">MGSVEPKRPVRVAGASGGFSDRVRAIESLARFEDVDVIVGDWLSELTMTMHGTAKVRNKSANEGKELTWEEEVRNAMFAENFMDCFEPAIEHLAKNKVRLAVNAGASDTEILAKIVQAKVTEKGYNLKVAWIEGDDVTSSVKNLIEKGEEFRSLMHNKSLKEWGLDPVCAQCYQGGLGIARALEEGADIVICGRVSDASPIIGAAAWWHGWKANQFDELAGSLIIGHLLECGSYVAGGYCSDFKSIMKAGKHIDMGFPICAIDYKGEGVMQLEKNRGGVMTVNSCTSQLLYEIQGPQYYNCDVTAWLEDIKFEQIGEDQVKVSGVKGLPPPPTTKVGITGFAGWQAEYHVYLCGLDIEEKCKFTEEQIRAELGEEMIKKFDVLKFMQNGSSVPDARNQDVATVDFRIFAQSKDRELLNMRNPNGFFRRSMTCFLQGCPGGSLGNDMRQAEGKPYYEYHPSLLPQSEMKQRLHLLFDHPTPIIDLPPPTEFRTYDRQQPTYETKNPVALDSFGPTVRMALGRVVLGRSGDKCSDCNVGFFVRHDDEWDWLRSLLTVAKIRELLGPEEDHGKPIDRFELPNIRAVHFLLHDHLDRGYDACSTYDTLGKNCLEYLRAKTVDIPVKFVERGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE9</accession>
    <name>A0ABR3YLE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">General stress response protein Whi2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF16">
        <property type="entry name" value="GROWTH REGULATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="32110" checksum="3F145A279F91EDF3" modified="2025-10-08" version="1">MAAAGGASSIITQVQQGGPPIQNLSSDVGLDETIAMDLRGTRFVLSRDELLTLPEFVLLSLFPNGLFPEGHMGGYNDDAAIQVDYDPASLQYMLDFFRGVAQSIPTDASPNPTQEGDVGGIDPMGGSKDDASKRAGIIVLREDLDFYVIPPHSGMQQAEIMDVKRAAARALLGQNGIFSGLKRSDEPGTTEAHLIEMLTAGGFDHDDAWGHRAGEPNKAVICSLALARLRSDIRGNEMSNNAVGMAQKLLLFWRKPARRCWWEGVHLENVEGVEGPLKVWIRRVWTLEMSVIGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLV1</accession>
    <name>A0ABR3YLV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000083">
        <property type="protein sequence ID" value="KAL1888882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047129250" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="19"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="285" mass="30452" checksum="88A849928F625346" modified="2025-10-08" version="1">MHSTGYTASLLACLPILAQAWNAPSYSGFNLVWQETFAGNSGTLPSTSTWNIITGNLGVNNELETYTDSTANLQLSGGNTLQIVPWESGGQWTSGRIESTYTFTPAAGAKTLAEADIRFGDDDPSTKQGMWPAFWMLGDSIRHGTAWPACGEIDALETVDGQLIGHGTAHCDITPGGACNEPTGLTSSVNIPDQSWHTWRVQFDRTSNNWQTETITWYLDGASFTSISGSQVGDEGSWTALCHSPLYFILNVAVGGNWPGSPNSATEDGYGALMEVAYVAVYSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMD2</accession>
    <name>A0ABR3YMD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Prostaglandin-endoperoxide synthase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008856</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1122" mass="124866" checksum="AA596D753A61DD96" modified="2025-10-08" version="1">MSDRNLVGEKPQASTSIHGTDTASSKSGPEKLVISGTITNRPPLAKGPQKQSSPGAFAKLSGLRAASKRPLPTQTGNGTYIVAKTQTGLREDIKHLTWANVKTVLDLAKSKKKGGPTDDRTMLMERVIQLVAGLPSKSRKRELLTANFITELWESLDHPPQLFVGDKFQYRMADGSFNNIHNPSLGAAGTTYARSVHSTVASPSALPDPGMVFDSVMRRGEYKSHPNNVSSVLWYWATIIIHDLFWTDHRDHNKSKTSSYLDLSPLYGSNQEMQDTIRTFKDGRLKPDAYADKRLLGMPPGVSVILIMFNRFHNYVADNLAAINEGNRFPRPPGSPDAEGLDERAKAAWAKYDNDIFQTARLVTSGLYINITLVDYVRNIVNLNRSDTTFTLDPRLDTEINSGTGEQSERGTGNVVSAEFNLCYRWHSCISAKDEKWIEDFYHDIFGKPAAEATMMDLMGGFIKFERSIPDDPGVRTFGGFKRGADGRFNDDELVDCMNDAVEDVAGAFGANNVPPAMRCVEVLGMLQARKWNLAGLNEFRKHFGLKPYEKFEDINPDPQVADSLRHLYQHPDFVELYPGIVAEAAKAPMVPGVGIAPTYTISRVVLSDAVVLVRGDRHYTVDYGPKQLTNWGYKEVDYDLNVNHGCVFYKLFIRAFPNHYKQNSVYAHYPMVVPAENVRILQSLKRDHLFDFSRPTAIPQRVNITSYGGALHVLEKQDTYKVTWNEGLGFLMGEPGNRFMLSGDTPLHAHQRQCMGALLYRDAWKADVKAFYASTVESLLQEKSYVLASKRQVDIIHDIGNIVHTHFAARVFNLPLKTAANPKGVYSEQELYMVLALIFVTIFFDIDPVKSFPLRQATKELCTQLGTLIETNVKLALGLGMRAMFSGAAPNKKAKDSLAAYGINMTKGLAKAGLDAKEIAWSQILPTAGAMVPNQAEVFAQAVDFYLSPAGSIHIPEIHRIANEPVSDEGDALLLGYAMEGIRLAGTFGSYRKAATGDTIVEDDGRRIPVKVGDRVFVSFVSAARDPVHFPEPDTVNPRRPLDKYIHYGAGPHACLGRDISQVAIVELFRALFRRKNVRRVPGPQGELKKVPRPGGFFVYMMEDWSSYFPFPTTMKVMWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMM5</accession>
    <name>A0ABR3YMM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">srs2</name>
        <name evidence="15" type="ORF">Sste5346_009101</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17932">
        <property type="entry name" value="DEXQc_UvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18807">
        <property type="entry name" value="SF1_C_UvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.486.10">
        <property type="entry name" value="PCRA, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF2">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE SRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="13">
        <location>
            <begin position="124"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="14">
        <location>
            <begin position="408"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="606"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1046"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1235"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="607"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="630"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1065"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1075"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="145"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1269" mass="139186" checksum="29F75351AA68BB03" modified="2025-10-08" version="1">MAGKPEVIDLCSDSDADSWDECIKIKSSPEASPVKKSTTATATSTKTNATTTTTSTKSTLVVTKTAIIPPAPIFARQHAAPPRPKKKAKTKATDDMLVAPRSKTTTIKTEQPDTYATSDSSLLSKLNPAQRRAVTSDANTVAILAGPGSGKTHTLTSRVAWLIDQVGYTPSNVIVATFTVKAAREMKERIGKVLGGGREKRIVLGTFHSVSLRYLSAYGTRIGLPKGFSIVDDNDSKSIIKRIVKRLNLELDTAMARGWISKKKSKGCLGTDEENKAKKAGHKESAENKDFLAKLQKIYDEYQSHLQSLNLLDYDDLLIRCTELLRAHPACVANVQAVLIDEYQDTNGIQFELMKLFAQACKRITVVGDPDQSIYGWRSAEITNLTRFLSDFPRTAEIALEENYRSSQCILSTSLQVIQQDQERYDKSLLPVHKKGTLPVLRRLQDSMHEAMWIIQEIRRATLLTGNMLNHGDIAILVRSAALSRPIEQALARAAIPYRMIGGRKFFERAEVKLLVDYLRVIHQPHNNEVLARIINVPRRGVGPKTIKGCLEEAETGNMSMWTLITKHCRGDIIAKTGINATTTKKISRFIDLVQRMQSRLRGALEELGEDDGEDGDGGDDEEDEDGDGEDKKPKAPKQKRDASISTATTAGIITDAFTTTEPGKAYDLVQLITALTEQLNYRNYIGETYGGDEEARWANIDEFVTLAREFMNNAKSLMVEDELPTLDGVEQTKETDVLNKFLANISLAADADKKQEGTDEPLPMVTISTIHAAKGLEWPVVFIPAAYEGSLPHSRSDDTNEERRLLYVAMTRAKCLLNISYSLFGSPDRDREREGRRSEQSLSPFLADIVDVWFAECGPAYDRALLHEMGDILGRDVPKERAIYQNLPTGVPIEDNVLPIDPLESSRYHNEDEDGGYEYSSRFKRQGSGVGSGNNAQQNSKRRRMMNEMPNYSGGGDSQGPWQRGYTTTMEAGFTMGGGTAYPGFTTASAHQTAMLEAEAAEAAKGPPPVISTATTAGDNKRKHGALPTGQQTFMQSFIRSNSTGTTAEVEKAAARSAPPPTKPTFQRSSSMFAMQHQQQAPAAPSGIPAELKSRSLGGVRGNLLPAAGVRNSMTGHPDKKKRYAHFSSSPPPAEEPKIVAEETSEPITRPQIDPRHGLPPPQPKQQQPQPLPYNYNHPRPYRAPQRPVAGKENLQHRVGMQANSLGVGMGGARPAASFHTTTYAQVQAHGSVSTNIRPAGGGGGGPSLAPMDRLRRPFKPPTIRRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMX0</accession>
    <name>A0ABR3YMX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Multicopper oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_008996</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04206">
        <property type="entry name" value="CuRO_1_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13910">
        <property type="entry name" value="CuRO_3_MCO_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="138"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="271"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="538"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="684" mass="76110" checksum="90C5299E7F119D65" modified="2025-10-08" version="1">MPDDTSDQGERLLRPEVPGVDHVHQWKEGEESQGSVDDNDEEQAQWPPASRRPPSRWQRLYGSIRRLFSPVVTIIMAIAVVMALFLLLTNGTLPMPTLGGSSSDIPKAHVTQKGPIIVLHPEDHIHREAQKIHLSWNITKGRIAPDGVFRDVILINGEFPGPTIEARTGDMLVVTVTNYLEDEGLSLHWHGLHMRSANHMDGPVGVNQCAIPANGGKFVYEVPTNDQAGTFWYHSHSEMQRADGLYGGLVIHKPAAEDVTNKDTVAVDQEILLLIGDWYQFSGKTIFAVFEDPTSNGNEPVPGSVLINGRGKFECSKATKADPVDCHAVDLPKLTLDKSLRYRVRVVNVGVLTGISTTIPDAHIEMLTVDGGLSVVVPDDIKNQVSNSIGVVYPAQRVDYILSWPDASTVGDDTQLFITVDGEYYVGNWQNPPSQTFDIVAASSSPKTLVKKPVKRASSPPPSTKAIDLRNIHGTALATPLPEPDKLYMIFAVVEILSHNRFIPKGYINHTMWIPQDLPLLSLDRSAWDSHQLVPWTGPEPVWVELTINNIDTQGHPFHLHGFDFYVVGSHEGLGGWDYYNPFFVPWKPPRGGLMNTINPIKRDTVYVPPYGYVILRFRADNEGIWVLHCHILWHQASGMNMAFQVLGHNEHGLGGTPQSFRAAEYCRTRNDKPKQKHEKHPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP71</accession>
    <name>A0ABR3YP71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein of the rab/ypt</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">YPT52</name>
        <name evidence="3" type="ORF">Sste5346_008634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="220" mass="23663" checksum="9860CF4FF7206359" modified="2025-10-08" version="1">MAARGPPGARGLNNRFAQFKLVLLGESAVGKSSIVLRFVKDQFDSYRESTIGAAFLTQTISLDEATTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQASSLDKAKAWVKELQRQANENIIIALAGNKLDLVAEQPDKRAIPTADAEAYAKEAGLLFFETSAKTAENVKELFTAIAKKLPTDQVGAGGRARPGQRPGVSLAPEGSNTQAAGNCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPJ7</accession>
    <name>A0ABR3YPJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="374"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="752" mass="82646" checksum="C709E152F8AAEE76" modified="2025-10-08" version="1">MAVNTGVPLPALQQLQLHDGNLPNGVDDPTSLIGQLSPKRTSQKTLVKRHNAHLKTQEAASTSDNDPRPVKQVILSEAYPACCKSLRELEAIPLASLKVETHHRGQMVIVKAVTAAYRGVGSVSVAVDAAGDADKLAIYNHSDTSLLSNLPAGCVVAVKEPYYKRNDGMSASDYMICVDHPSDVILLRFDDPLVPEELQLSAVDRAALDKTPEEWRSTGDLAFLQRDLPTAAFCYTEALVSKEEKTASFTAGIYAKRAGVNLLLGRYDGARDDALASCTGNAATDWRAYFTAAKATYGLCHYEESRKYFEKALQTQKSVSPTVDAALQREYNRCLARVREETEGTDDAYDFPAMYSSLSLQKNQVHLDRGSFLRKTQVRHSDFHGNGLFAVEDIAVGDLVFVEKAAFMPNQYFEPTRASAALYATMVRQMCDNPSVAAEVLQPLYGGELERTGKEGEIVDGVPVVDVFLAETIRLKNCFSAPLSTLDDTRPETGPYQERALAKGLWKYASYLNHSCVPNTMRSFLGDVLISRAIRPIKKGDELFQQYIPVKADVRARQAELQAGWGFVCQCPLCQTETTEAAQAGHAHRRSLLMAAEKLASKHLPHRFPPDSAVRTMEKLSKQMVASYDEAGEVYGDGQPRLGLVYPTMWLLRAHRCRKRHAKVAQYAEQTLRCFGFGKPEVDGGPASMYSQPGGPLHTVHVVSALVMGREAHRALGQTKEAEAFDAAGKLGFRMVTGFSEDVKAINEEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPT0</accession>
    <name>A0ABR3YPT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="16"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="359" mass="37365" checksum="5F8EC32CB71E527C" modified="2025-10-08" version="1">MPSEQNMRWTLRGPSGGVDNLEYGPAPAAQVTAKLGANDVRVTMHAASLNYRDIAIAKGSLPATQPTPGTIPGSDGAGVVQSVGSNVTAFKVGDKVLPHMVHPANNDFLPRLDNISAGLGQALNGTLANKAVFPADSLVPMPSNMSFTEAATLGCSGLTAWNALFGLRGREVKAGDYVLLQGSGGVSIAALQFAHAAVATVVATTGKGGDVAARLTKLGAAHVLNYKKDPDWGTTARKLTPDGRGFDHIVDVGGGSATLGPSLQAIRTDGIISLVGVLDAGNISPENKVDMMAALWTVATVRGVLLGSKNMFRDMVAFCEKHDVKPALDDVTFSLADALSAYKRLEEQKHFSKVVIEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ22</accession>
    <name>A0ABR3YQ22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000073">
        <property type="protein sequence ID" value="KAL1889489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="62"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="262" mass="28522" checksum="09BE4DD5545B8F50" modified="2025-10-08" version="1">MAAIEVDDIIYREWAIDRLKSYEKVGGDHYVHATKFVELMCATEDKAMTRVDWEPIMAGIPRRWAAPRSVPSPWEGVQDLTAFGPACPQVKEPLFDVPGLPVFGPQPSKSLSILADTEDEFRCLTLNLFAPATLSEDGTKLERPSKLLPVMVWVHGGAFRSGAGGVDLYDGTPLVSRSLDIGRPVVVVTLNYRLGVLGFIHSKQLLDDAAAQTDLPEHFRSTGNLALLDISVAFSWIKNNIAHFGGDPSNIMGFGESAGSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ30</accession>
    <name>A0ABR3YQ30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="69"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="304" mass="34929" checksum="4267648D118E9FE1" modified="2025-10-08" version="1">MALPTDTKTPAPPPAAESPPINDGFWMRALALFLVSFANMQWYRRWKKSNWGVFYISSTLCVRCCERTRLNEARAMQLVRQHTAIPAPKIYCSFEHKGLVYILMERMPGKPLANGWVFRSDTSKAKILAQLKPMLAQLRNVPRPSPQNGHGLPKVNADVVSGIDGGQFFDGNLPNKRFWGPFNTVKDFHRGLRGNLMVVPDEYTEERYTDLRKLIALQEDYVASPPVLTHGDLSANNILADGDNVTGIVDWETAAWMPAYWEYTNAWHVNPHNPYWQEEVPKFLEAYPVELEMEKLRRRIYDTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR01</accession>
    <name>A0ABR3YR01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RCE1</name>
        <name evidence="13" type="ORF">Sste5346_008662</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="173"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="342" mass="38208" checksum="86B7BBB0DB637CC6" modified="2025-10-08" version="1">MPAVKGLIDKYIWHKQKQEIPPPITTRTAVSLLVVYTVIYVAPFYLSKLTRPSPSLSRDAPSVIRARIASVTLSCAICSVVTFLLLTTNGKPEDGTRLLNFDALHLMGYFPVGLAETWNALLLTAGLFLGPLFEYFVVERGWRAWAGLDSSDGSMRPRLFGPLYHLAEWADWRNLVAGPITEEVLFRAAGVPPLLLAHTPVRRTVLLSPIVFGLAHLHHAYEFSVTHPSIPKAHVVLRSLFQFAYTTLFGSYATFLYLRTGSLLAVCVVHSFCNSMGLPRFWGRVQRNPDEGSGNNNGESQQPQGSLLWTLAYYILLVAGAVYWYQHLWTKTESHMALVSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRD1</accession>
    <name>A0ABR3YRD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007994</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF131">
        <property type="entry name" value="TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="484" mass="52880" checksum="D2B829E90CFD3128" modified="2025-10-08" version="1">MMDLYIQAMMAWKNMSEDDELSYFGLSGIHGRPYVAWNGVEQVDGAPLTGYCTHNEVLFAIWHRPLVAVFEQVLAQHIQAAAGLYNATPEIAAKYRRAADTWRHPYWDWAIDKALPDAVVQSNITIRMPPDGRASQTVANPLLHYRFHQFPLNSTLFPSDDDDDYHLASFRETLRCPDPYNNFTSNPGMASANVAGIDLAGQVYNIYTRVSDFGSMSSTACDSTSFEQEHNEVHVAVGGIHPMGHFAHLGYSGFDPLFMMHHAAIDRHVALWQAVHANASMFGSSENYQTKTGQFATAPGTNITANSPLKPFYALANGTFHTGNSARDIGTFGYSYPELLAAQAQMALGSSGNGSQTVSASSVMTLSRAVTAEINRLYAPSNTSSQKYPPYGPSSLSSRSTSTPQKAYFVRIGIEKAGLLLPAAVNIFLGATLAGRLLLLMSPPQGRVHGEISLEKALTASQLDGRPTEDILRQSFRWEVATVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSU4</accession>
    <name>A0ABR3YSU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal STAND N-terminal Goodbye domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61504" checksum="7124CBF0A1E15A8A" modified="2025-10-08" version="1">MARFVQAHPTEPDEIKQKCRIRDRADWTGVFDKLEAAKNAYSQTDNSFKATFRKVYRKTADHSGGAPMAIVDAAKDLLDVDYASPVLGALRLVLDAASKAAKLRQDMMGAFDNIDRNFTEVEVYQQEFAGDENIREASIDLVASVLYAIESVIGFFISKTYRRLLRATFTIDEYRKRIDGSLNDIDKKASELLREVQMSKTHRDHMFQTQALQDTSMTQYGVAQLHSMFHGTRNAMMSMMNDLVMRMDGISAQVSRPPSPRPVTPVYLISAAPSPEPQPLGISPQELLHWVGITDMASQDLEYMESRNHDEISPAEQGRAEQLVVHQQLQSWLSVPASSQLLIHGNDEGGLSPVSALSLFCASLAFNLDSHPRIIRLLFFCGLHSDTGRSYRADDYYEEDDTGGRAIISSFICQLLCAHDFGSELPFGPEIEDTILYGEVNELCNVFSTLVRQLPRSVVLVCVIDGAAYYERREFLDNTAVVLAHILRLSADSSVLAVFKVLITSSTPTIHIRQPFPDEMILSMAAMGDAEWEPSQARLNRFLSNGQDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTL7</accession>
    <name>A0ABR3YTL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Calnexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007547</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF1">
        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044962568" description="Calnexin" evidence="8">
        <location>
            <begin position="22"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="524"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="62495" checksum="1DE8619C2B04829B" modified="2025-10-08" version="1">MRINSVAAALGAAMLAGKAYAEDVQDDSAAAAASSVAPELPTFTPTKLKADFLEQFTDDWEKRWKPSHAKKDMKSSGKEEEEWAYVGEWSVEEPTVYKGMEGDKGLVVKNKAAHHAISAKFPKKIDNKGKTLVVQYEVKLQNGLECGGAYLKLLRDTKALHQDEFANTTPYVIMFGPDKCGHTNKVHFIFNHKNPKTGEYEEKHLSSPPTARIVKTTELYTLIVHPNNTYIVQQNGENVKEGSLLEDFTPAVNPPKEIDDAKDTKPEDWVDEARIADPEAKKPEDWDEDAPFEIVDEEATQPEDWLEEEPLTIADPEAQKPADWEDDEDGDWLAPTVPNPKCADVSGCGPWTKPMKKNPDYKGKWSAPLIDNPAYKGVWAPRKIKNPDYFEDKTPANFEPMGAIGFEIWTMQNDILFDNVYIGHSVEDARKLAEETFFEKHPVEQLLELADKPKVEDEKKPIASDLKFLDDPVLFIKEKINAFIAIASIDPIEAVKQVPEVPGGVAALVIVLLSGLFILGGSAPAAPTGKPAVTQSKGKDKTEAAAASGVDTSKEGATKRATRSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU12</accession>
    <name>A0ABR3YU12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cct1</name>
        <name evidence="11" type="ORF">Sste5346_007390</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="623" mass="66428" checksum="06C448E72B7836A6" modified="2025-10-08" version="1">MTSMFEQSRQGTLFLGGQKISGTDIRDQNVMATQAIANVVKSSFGPSGLDKMMVDDIGDVTVTNDGATILTLLDVEHPAGKILVDLAQQQDKEVGDGTTSVVLIAAELLRRANELMKNRIHPTTIITGYRLALREAIKYMNDHISIKVEQLGRESLINIAKTSMSSKIIGADSDFFANMVVDALQAVKSVNSRNGETKYPVKAVNILKAHGKSATESVLVKGYALNCTVASQAMKTRIPDAKIAVLDMNLQKERMKLGVQITVDDPQQLEQIRAREAGMVIERVEMILKAGANVILTTKGIDDLVLKLFIERGAMAVRRCKKEDLRRIARATGATLLSTLSDLNGDERFEASYLGHAEEVSQVRISDDECILVKGTKVHSSASVILRGPNDFSLDEMERSVHDSLSAVKRTLESGSIVPGGGAVETALHIYLEEYAGTVGSREQLAIGEFAQSLLVIPKTLAVNAAKDASELVAQLRSRHALSQRVLDKPAAGGHGAAGAAASAGAAGATSGAAGGAAGAGAGAKDAQQLASQAATSSKSAAAKQQQLDDEKAIARKKGYKNYGLDLMRGRVVDEIKAGVLEPSMSKVRQLKSAVEACISIMRIDTLIKLDPEQQQEDDGHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU91</accession>
    <name>A0ABR3YU91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM3</name>
        <name evidence="11" type="ORF">Sste5346_007298</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="13"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="99" mass="11043" checksum="EF7767443804C964" modified="2025-10-08" version="1">MADDASDAGPVSEPLDLVKLLLDELVFVKLRGDRELKGRLHAYDSHCNLVLGDVEETIYVTEEDEDEEETPDVRTVSRKSEMLFVRGDSVVLISPVPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ7</accession>
    <name>A0ABR3YUQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000047">
        <property type="protein sequence ID" value="KAL1892120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF11">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="136"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="45773" checksum="C617515B3D99B439" modified="2025-10-08" version="1">MDPSESEEVARRGTQGTIWRRLALVGALIAILPKLLVSYALRRLFGPPSDVPGDLQRSIVRGASTLPLRLLYGRQAPFDVESMLSAPRFQTYDRQLCTKVSTGLGSAYWICKGRPRKLSEAPRTQHLDSRESDLVLFYIHGGAYVFGEPLGSTLLLLRAAEIAAARGVNVSIFTVGYTLAPTGKFPLQQRQAVAAYRYLLDVEHISADKIVVAGESAGAHLAMTCLAGIAQANLPKPAASLLLFPWVSLTNSSPSFERNKYKDVLTKSLLDRCAAEVIGTEADKAESNVYEGIDWDQLELVDLTRPPTKGDGKTLNWKQIMPEFTWINVGEHDMFYDDIQTFIRQATDDGARIELDITPKKPHGWHAGDRPNAQKLIEMSPDAEVPAGMLPGCENVGNALLRVWDEAVSKSSSRAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVA6</accession>
    <name>A0ABR3YVA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL6</name>
        <name evidence="6" type="ORF">Sste5346_007718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000054">
        <property type="protein sequence ID" value="KAL1891259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049633">
        <property type="entry name" value="Ribosomal_eL6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01170">
        <property type="entry name" value="RIBOSOMAL_L6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="201" mass="22397" checksum="DA15881D848E06EC" modified="2025-10-08" version="1">MSPTAPSTKKFGKSSRTVPHHTQRAQKWYPAEDDAQPKKVRKALRPWNPRKSLVPGTILILVAGRFRGKRVVLLKNLDQGVLLVTGPFKINGVPLRRVNAKYVIATSEKVDLAGVDAKKIEEIAAPNYFTADKAKQKAGEEAFFQQGEKPQKKEIATTRVADQKAIDKALIANIKKVELLGSYLATSFSLRKGDKPHEMKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM6</accession>
    <name>A0ABR3YVM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPI12</name>
        <name evidence="3" type="ORF">Sste5346_007296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000048">
        <property type="protein sequence ID" value="KAL1891952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="304" mass="33183" checksum="307431565F812487" modified="2025-10-08" version="1">MSLLTLLGALVVLVPVLYMYTVSVVAGRFPTLRNKRICLLIAHPDDEAMFFAPSVLALTRPETGNHVKILCLSSGNAAGLGETRKRELVKSAMTLGLRAEDDVFVVDSPDFQDSMTTEWDNTAIATLLASAFTPPVPGAKKSADGPPGATIDVLVTFDDRGVSGHPNHVSLYRGARRFVAALVQGKPGWRPPVDLYTLTTVPFIRKYTWVFDVLPTVVSWGFRLRSADPKIAKTKEHPGALVFLADLNPSATGGGLGTAWRAMTTAHQSQMVWFRYGWIALSRYMVMNDLRLEGNFGPADLKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWI2</accession>
    <name>A0ABR3YWI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-dependent DNA helicase Hrp3</fullName>
            <ecNumber evidence="14">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">hrp3</name>
        <name evidence="14" type="ORF">Sste5346_006833</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="14"/>
    <dbReference type="EMBL" id="JAWCUI010000042">
        <property type="protein sequence ID" value="KAL1892750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18660">
        <property type="entry name" value="CD1_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18659">
        <property type="entry name" value="CD2_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041150">
        <property type="entry name" value="Cdh1_DBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025260">
        <property type="entry name" value="CHD1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18196">
        <property type="entry name" value="Cdh1_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13907">
        <property type="entry name" value="CHD1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01176">
        <property type="entry name" value="DUF4208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Chromo" evidence="11">
        <location>
            <begin position="284"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="11">
        <location>
            <begin position="384"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="482"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="800"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1078"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1351"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1606"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1110"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1357"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1397"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1431"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1459"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1611"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1621"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1633"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1651"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1738"/>
            <end position="1748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1759"/>
            <end position="1783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1805" mass="207663" checksum="0654A14D35994FBF" modified="2025-10-08" version="1">MSASPASSPVNGYASAASDSPARNGAAGHASDSDLSDVEPTYANAASPSASAAPEDDDEDENDEDDDLAVANDFEDEQSEPSDNDVSDDADFDDAQSDGDADADADADPDLDVAALDHDDESQASSDSGHAPKRKASAMLAEDEYMRSNPELYGLRRSSRPAQRRRIVSDDDDSEDEPVVRRKPKPRRLLETSRQSSKRGTPARNTSVDESDSDNYGGARARSFQKKARRKQETQPSLYTEKRWSSRRAAQVSVGKYNESDFEDEDESEMTPAQWMPEVEDNSPYIEKIVRHREKEGVAITPDSTRHDYEYYIKWQGKSHLHDTWETTASVAGFRGFRRLENYYRKIVEFELDMRFGGDDYSPEQREQWLLDREREEQAHEDYTKVERVVAKRKGEEGVEYFIKWKGLQYDECTWEIAATVSEHAQDKVDQFLDRSSRSWTSDRTETSLNTRSRMTKLDSQPSYITNGELREFQMKGLNFLALNWTRGNNVILADEMGLGKTVQSVSFLSWLRNDRGQEGPFLVVAPLSVIPAWCDTFNHWAPDLNYVVYLGPESARSVIRDYELLVDGNPKKHKFNVLVTSYDFILQDWEFLKSIKWQVLAVDEAHRLKNRESQLYSRLVSFNIPCRVLITGTPIQNNLHELSALLDFLNPGKVVIDDDLVQLGMADQKTEEENDDDDKRRETQEKLTSFHAAIAPFILRRTKETVESDLPPKTEKIIRVELSDVQLDYYKNILTRNYAALSDASGGQKQSLLNIMMELKKVSNHPYLFPGVEESVLKGSERREDQIKGLIASSGKMMLLDQLLTKLKKDNHRVLIFSQMVKMLDLLSDYLRVRGHTFQRLDGTIPAGPRRMAIDHFNAEGSDDFCFLLSTRAGGLGINLMTADTVIIYDSDWNPQADLQAMARAHRIGQKRPVNVYRLVAKQTIEEEVIKRARNKLFLEYLTIQAGVTDEGKELREQFKEKGLKMDEAKTAEDIQWILKMRSQNLFEQSGNQEKLEQLDIDSILENAEVTKTNVDDKLNLSTGGIDWDNWMQVTDVKVDELALDWDQIIPAERLAVIKSEEEKRLHEEYLNKAMEENAPRRATLKKRNAAVANDSDRADRLAKKRQREKQEQEEYEERQAALRDPRRPLNEKETRNLIRAMFRYGSFDDRSEEIIADARLGDRDRDFMRSVVEDLVALSKQAVDANAARIREEQEKAGKALARKDKKAVLIDFGEVKKINAETIVERPPQLRLLHKVLEEHGNPHSFRLHDASKAAHYTCEWGAREDGMLLVGIDRYGFGAWTQIRDDPELDMSDKFFLEEHRVEKKEERKKGDEKSIQSPGAVHLVRRSEYLLSVLLAKYSDDDAAKKAVENHHRSKKTVNGHRRGDDLSRSPAPLKRPSAHKNRDRLDRDRPISSSDYLNLRPQSGVSGGGERLLTPRSDFKRKHEHDHNDRDRKQRRVTDGDRRDSNGVGPSSGHKDSQPKEKRKKLDAETLEQLKAAQTKAVQRFEELMKLDDGKLDYRDDEQVMWSLLKPVRDNFKTIMETTPERVEKAKERAAIMGKELRQIGDCVIGLKRNQTIPAATLDSLMPRFWDFLSSIWPINEVAVSGNQLSKMYEALRAKDEKGSSNGGGGGGSNNGNNGNSSGARDSSSRPDRPSRDDLEDGEIDSERDNRRDSRREHEHRDSRDHHDRDRNDRDRDRERDRDRDRERDRDRDRDRDRNRDRERERDRGRDRERERDRDRDATRRSTGLLGDLRRDDRHGSSESRSSPYAAETGDRLSFRKDPRRDYQPQREWDRLRPTPWQQQQQQQQQYTASRPNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX03</accession>
    <name>A0ABR3YX03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF380">
        <property type="entry name" value="SYNTAXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="210"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="40887" checksum="AFC89F18C1857C02" modified="2025-10-08" version="1">MADTALLHVHRHKQHSAKGLGPGEELDLVTTKTLRWDATNMENAGSFASGDPNAILNECRSIDRGIDQIDQNLNQLRMLQDRSLNEADTSGSTTSKQLDALASDTMALYRQLTERVRQVKSQREAQQPKNAPQVGRVDRRLKQAIQSYQQVESAFRKKTQDQMARQYRIVRPDASESEVRAVVEDTAAGSQMFQQAMMQSDRRGQSRAVLSAVQDRHAALQKIEQQMVELAQLFQDMDTLIVQQEAQVIQIEQKAEEAVVNIDKGNEEIAVAVTTARKTRKKKWICLGICVGIILIIVIVVVVYVLINKQGSSKKRSIGARGLDFTSDQLAARIYEQANAVVRSAPGRLSSRYVINTDFTKDDPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX47</accession>
    <name>A0ABR3YX47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06587">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058997">
        <property type="entry name" value="YycE-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058998">
        <property type="entry name" value="YycE-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22659">
        <property type="entry name" value="YycE-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22658">
        <property type="entry name" value="YycE-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="132" mass="14531" checksum="48D50CEFFDA36649" modified="2025-10-08" version="1">MSIATAHLRVARPTNDINALIPFYVDGLGFSELFRFDEHDGFDGVMLGLAQASYHLEFTAKKGHDAGRAPTQDNLLVFYLPDKAAFDAALMRMTAAGFPPVPSFNPYWDACGKTFEDADGYRVVLANRESPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU3</accession>
    <name>A0ABR3YXU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Wbp11/ELF5/Saf1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000041">
        <property type="protein sequence ID" value="KAL1892895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="316" mass="34750" checksum="2861E63668367860" modified="2025-10-08" version="1">MPKEKNYNPVQAQRKADKAKAIKKGKADVAAARNERLSKKNPDRIRKQIEDLKAITEGGGKLTTHEQQVLEGLEKELKAVVKAREALGDKAPSFGRGDGSYRSNDRNDRHDGGFGGRKRRRDDDDDNTSGDSDVPDDIRSIPMPRDTPPPIPKRYLDEWYAKRRAKRNANANSEPLGGGRNAGRGEGRNESGRGGSPTPSTAPPPAAVAKPVEVKTVYEAKPVVRDLQKEAVSAFMPTVVRQKLEKSRGMGGLLEPEEADRLEREGYLKSSVQNVDENNYHDNGRASRVTAQPRQPTTSGPRAFHATVEDAEDEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY85</accession>
    <name>A0ABR3YY85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="334" mass="37129" checksum="42FAD9853DCE41B3" modified="2025-10-08" version="1">MVSESEARAIYRDAIHFDGLNICNFSREIFEAWHKGGIDGVSVTCGLWEGFRGSIANVVQWKKWFEEHSDLIVQAHTVEDICQAKKDGKTAVLLSWQNTAGIEDQLDYLRVFRDLGVRKMQLTYNTQNYSGAGYTEPKDSGLTGFGQQVVDEMAKLGMVVDLSHVGPQTTRDTIEYAPEGKPPCFSHILPGGLKEHPRNKTDEIIKLLGSKGGFVGLSQFGPHMEKGNDSTIDDYVAALDYVIDLIGEDLVGVGSDASEGHGRPSDFMAWCNKDKGYARQLTPWGSQKVVKPLGPLAEREELAAAMGRAGWSEEKMRKVLGENWLRYLEKIWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZN5</accession>
    <name>A0ABR3YZN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Catalase A</fullName>
            <ecNumber evidence="9">1.11.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CAT1_2</name>
        <name evidence="9" type="ORF">Sste5346_006354</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08157">
        <property type="entry name" value="catalase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF26">
        <property type="entry name" value="CATALASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="8">
        <location>
            <begin position="6"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="525" mass="58697" checksum="8A7B1965C0B90B95" modified="2025-10-08" version="1">MSRQYTLAEGNPLPNNATSVQLRNGQGGGFVLLQDTQLIETLAHFSRERIPERVVHAKAAGAYGEFEVTHDVSDLTSANFLSEVGKKTKVLLRVSTVGPERGSADTTRDVHGWAMKLYTEEGNLDWVFNNTPVFFVRDPIKFPSLNRSHKRHPRTNLPNADMFWDFHVGNPEGIHEILHLFSDRGTPRSIRTMNAYSGHTYTFTKEDGSFKYIKVHIKSRLGVHNMDAAEATKVAGENPDYLVQDLFDTVEQGNFPQWDIFVQVMDPAEAERYRINIFDMTKVWPHADFPLRQIGRLTINTNPRNYFADIEQAAFSPSNMVPGWGASADPMLQARMFAYPDAARYRLGVNYQMLPTNKAVAPVYAPTQRDGYMNFSDNYGDDPNYIGSMLRPMTFKKSVVAATAVSEAALKHQKWVGEMSNYFTTTPGPKDYEQATALWHVLGREQGHQDRLVENLAGNIAGVTNAALLQEVYALFAKVDVSLAQRIQAGVEAKQAQAKQAAAANGTNDTNGSTIHIVRDAFPYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZY8</accession>
    <name>A0ABR3YZY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006091</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF5">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="136"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="41904" checksum="2668F6B19DC06C91" modified="2025-10-08" version="1">MAPIKVGIIGFGLATNCFHLPFILPNKDLEVYAFLQRAPPSAASSQKYGHCTEKFPRAKHYQTADTFFADEQIELVVVAALNHVEFVTKALEAGKHVVVEKPFTPTSAEADKLIALAKEKNRILTVFQNRRLDSDFRTVQHLVTSGALGDVKEAEIHFDPPSAPWVMNWTDRAYTPGRGIVFELGTHTIDQALTLFGKPAAVTAFFRTLRGMDSDIHDTFQLVLEYDGPQKDLVVTVKTAIVSVLKDQLRFALKGTEGTFLKFGTCPQEDRAIANPGVPATDPDYGTEDRRIWGTLTTKTEFDAATQHRDADTGYYIGAYPSLPGYYRGYYENLVEAIRGTAPLGVDPQTSRDGIRLIELARESHEKRATVKWTDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0V8</accession>
    <name>A0ABR3Z0V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045517712" description="Extracellular membrane protein CFEM domain-containing protein" evidence="3">
        <location>
            <begin position="34"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="35832" checksum="36FF72949C7CFD85" modified="2025-10-08" version="1">MDTRRQSRRRLAPAFSTLFLVLLLLLQTTAVRAAFTNNFDAYPSGTRSCLNASANASGCDGDDVTSMNDCLCGNTGNFVISAAECIGKADYADLETVYTTMASACSFSNTPLSVSQKDFLSAGNGTFSSSTTSMPSTTSGASSTPSLTTITTTSNGHVETITETAGSPKNTGGSSSDNNNSGMSSTTRTGIIAGATVAGVAIVAVFAFFLIRMWRNRQPTEEHRPMLGGDGTVSETGVAGGRGGGPGSQVSGTELSHLSGANTYDWKAGAGGGDPSENKWPHDPYNSSPSPNLLYQQQSGGVYELPVQDGAQHPVEMPATPMVMGATPVHHHPQGQPTEYGQGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z153</accession>
    <name>A0ABR3Z153_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_005853</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="857" mass="92565" checksum="6C4708979E502968" modified="2025-10-08" version="1">MMPPFAPASASASATSTSPPSHVHQPPAWASNLANLLPEQDDDTLATNGDEPSGNGRAKRPRVALACQRCKVRKQKCDGRQPCSKCAPSNVVCEYVVPQKPMPFGKNQYIKSLERRVAELETLLAHRGVAEVGTDHWANVPAPNNIAAAGGDVSMLSTSAPVNSVPASTNNGGHTRAPSAPSEGHSKASSPVGRPAGAATSAKDPDEAILDWQDGGLDPVVSVLRSLSLDVNGSGYIGASSHVALGRLFNFLSRSQRPSTTSTVNIGGHHLNQHQQQQQYCIDNASIVRRRSSSFHQLSLGAANGNGTAAPAAAPSTTATDAASNASGTTTAAATAAAAAAAAIEPIDFADVPTNVADRLYVGYIKNIMTRFPVVHSVWLRQVHHRRYGLTDVFEATILHLVYATSGRFIETTGESGPYHAKRHYASAMRALDTMLEYNDIRTIQALMLMAIYCLRDPAGPGAWTCSRMALLVAIDHGLHRQTKAVAQSRSMESELRKRLFWACYCFDRQISIPMGRPLGIADRDIDIALPLDVDEDITEDALAVIELPTRVSPADPSTSLTSFVLIAELRKIESAIQEAIYRVDNNKDDGTAAIDDAVIDGFLDRLEQWKAQIPHDTTIVKDIPGFPYDGYYFYMVFYYKCQRLLLYPVLSDLTVSPRFLKECAKACAGVCGAYKRLHQTLAVGYSFMALQNVFIAGLTLVYCIWLCPSDIFDMATSNGIHDCSIVLFVIAERVPAATKYRNAFELIRQKVIDQIISQAPDHRQPRAALSGLTVELAPSVHAFEVNMPFEVGNGSFEQFSQIITDMSGGESFVAGLTRFHAEMSSGGGVSNTSQNDMVDPALSSIPYESVFGLSDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z170</accession>
    <name>A0ABR3Z170_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1893937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="11"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="178" mass="19939" checksum="E05193336BCE5342" modified="2025-10-08" version="1">MNTKGISKIITKIDRVRKHNRRPISELVDRMKLVPAYAHQSTTLTDTPESIELGNHLIASQWVAETAETRSGLDEDQVRCISTLAIKDLDEGAATIHPFVDGNGRVSRLMMQGDLMRQGYLPACLKDLTRDEYLKMIRHAADGDPSLLVDCYVTAQLELLTAALMEDRMKTRETSKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1C3</accession>
    <name>A0ABR3Z1C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="432" mass="48877" checksum="60DE95C397ED7BA0" modified="2025-10-08" version="1">MSSLSSLERGCPPSRRRSCLACTKAKRRCDNTLPSCVRCRRRGVECLYPVRKDNSEAVQQTQQTTGKKTTSTTTTTDGYTFVPMPPCDLVLDSPTSTSTPTTSFSLNTPPAFVDTPLVDSTPSLSLILTTPLPLSAPLAAANWNFVSRIVASHLGHAMDIIRDAPRLFVVENRLPWSHPLLYRECMPRAMEDALSSCALYQAKNAVNTAVVLRTIDARLHDLLGAPEPTTLLECIAKTQALLLYNIIGIFDTDINARATVENTQPLLQHAARRLLTFIKFDALQDAPDEAALLVTARAFWDEWVLMESARRTFLISLYFMHLYCIVMGSPSRTCDERRYLNRYWTISSSLWHATGPLDFARAWRANRFFLARVGNFEELLSEARAEDIDDFSRIFLSSLMGIKEFSMWMAKRERDKPDEAVWQKEETERYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1H2</accession>
    <name>A0ABR3Z1H2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000035">
        <property type="protein sequence ID" value="KAL1894042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="183"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="345" mass="39315" checksum="C6ED88764294226F" modified="2025-10-08" version="1">MATAPPSPSIPVIDFGPFYSGRPEDAAAVGKAVYEAFRDFGFAYISNHCIPEESVKAAFDWNEKFFNLSQAVKEKVPHPPEGWWHRGYSGIGREKVVQMVYDKDSIGNLRKVPDFKESFEMGRDYNVGRLKNIWLPEEDLPGFRDFFVKFFEQGYQMELDLLRAIAIGMGLDEKFFWAYHVNKDNQIRLLHYPAVEESLLRDGKLERIASHTDFGTLTMLFQDSVGGLEVEDIYEKGKFNSAPYIPGTIVVNIGDFLQRWSNDQLKSTLHRVRAPPFVEATEADGAGDSTKQRVTRPRRSIPYFVTADHEKVIDTLPGCYGPENPKKYDPINSGEYIAMRLNATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W9</accession>
    <name>A0ABR3Z1W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">STE14</name>
        <name evidence="12" type="ORF">Sste5346_005995</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="314" mass="34305" checksum="DAB675EBAFD97498" modified="2025-10-08" version="1">MESSTGIDISANGATLRRPSPISTASTASSASLGSHHNGQSSNAVPPPGIGSPETPTSGFPPDAASYPGQKRSLAGIALRAFCLGAALVVGVFLGTLLALLPRLFPGTTGIDLLSPLWRLPFFLAALSTFHFLEFWTTARYNTQATSIYSFLLTANWPAYAIAHLAASMECLVRYTLLRNVDVWSYLPFTIPRTAVVMAGFLVVAIGQSVRTAAMVQAGRSFNHTIQHKKATSHALVTDGVYALFRHPSYFGFFWWALGTQLVLGNVMCLAGYTAVLWRFFSMRIRHEETLLVRFFGDDYVQYRKRVGTKIPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D4</accession>
    <name>A0ABR3Z2D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol dehydrogenase</fullName>
            <shortName evidence="6">HDH</shortName>
            <ecNumber evidence="6">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_005979</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF14">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="436" mass="47323" checksum="70E3EC73CD9425AC" modified="2025-10-08" version="1">MTRTYLKKATPTASKAPSTTTDVPTVVRGVIEDIRKEGDAAVRKYSEKFDKWSPESFKLSKADIERIIASVPQQTIDDIKEVQANVRRFAEAQRESIKDFEIETLPGVFLGQRNNPINTVGAYVPGGRYPLLASAHMTIVTAKVAGVPNVIGCTPPIRGEIPNATVAALHLAGADEIFVLGGVQAVAAMAVGTEMVRKVDFIAGPGNAFVAEAKRQLFGEIGIDLFAGPTEVLIVADETADPFMVATDLLSQAEHGPDSPAVLITTSEEVGKKTIEECENQLKTLCTADIARVSWSTFGEVVLASNIDEAFAIADEYAYEHVQVLTKNPRDSLEKMTHYGALFLGPMTCVSYGDKCIGTNHVLPTRGASRYTGGLWVGKYLRTVTYQEVRNAEQSGKLGRLCGRAARAELFEGHARSGDLRAHEYLGDKFDWITKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2S2</accession>
    <name>A0ABR3Z2S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_005859</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000033">
        <property type="protein sequence ID" value="KAL1894360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF8">
        <property type="entry name" value="BENZIL REDUCTASE ((S)-BENZOIN FORMING) IRC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="252" mass="26476" checksum="47995CDD3F98115B" modified="2025-10-08" version="1">MGKVILVTGASRGIGLATARHLLAHSHKVVLVARAAQPLIALKKEFPSQVAYKATDATDYTALASTVDLAVSTFGQLDGVIINHGALTPVQRLADADLDAWKRLYDINVFSALALSKASLPALRASHGRIVLVSSGAAKKGYASWGAYGSSKAAATSLVQHLAVEEPDIVSVAVTPGRVDTDMQKEIREQGEAGGMDAKVLATFVDAHADGILNPPEAPAEVIAKLALDATPELSGTFFNWNDSHMGAYHWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3N9</accession>
    <name>A0ABR3Z3N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">mRNA-decapping enzyme subunit 2</fullName>
            <ecNumber evidence="11">3.6.1.62</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DCP2</name>
        <name evidence="11" type="ORF">Sste5346_005607</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.62" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="95"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="374"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="589"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="888"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1022"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="470"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="642"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="719"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="752"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="786"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="825"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="852"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="891"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="933"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1058"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1117"/>
            <end position="1128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1145" mass="123628" checksum="5A2268134088C5DA" modified="2025-10-08" version="1">MTSQKMTLDDWLDDLCVRFIINLPQADLASMARICFQVEEAHWFYDDFIRPLDRNLPPMSLRTFCLSIFKRCPLLAPFPIENHVRAFEEFLKYKTSIPVRGAILLNETMDMALLVKGWKKGANWSFPKGKINMDEDDLDCAVREVDEETGFDIRSAGLVPLPEDVKYIDTNFRDQQIRLYVFRNVPMDTHFEPKTRKEIGGIQWYKIADLPSYGKNKNNPNANSANANNTNGHETEDPTPANSNRFYMVAPFIGPLRKWIASQRKKDAARAGGNAYLTPQLAHAEDTYTEDEGNALPEPVPQNTTMDPNDILANANRELRQMLRMPPLPSDDQQHQQQQQQQYQQAPAVQPPPDAFADSSQNKANALLAVLQKGGTANAPPPPLPPPSGGQGGISLMGLLGQVSQQPQSNAPPQPQHQQYEPQQPPFQQQYQHQQPPPPHHQMPQPGPPPMQGQPSPGYGQYGAPRPNPQQQQQPQHQQQYTHAQQLAQQNQHLQQRFQLHGQQHKPQNYPYNQQQQQQQGQNINPFAPNPQAQPPPPYTANGQQAHAQAQAAAAAFRNQQHAPPPIPLLHPQPLPPVVQKAMFAREMLVSPDVGGNNGNNNNMMLPPPPPPPQQQQRGQQAPLSNHAAALLNTFKKDDGAPRQQQQQAGGGPQADAGGQDWPQQQSQQPRHASHAVPQQQAQQPQQPYATLPHNFHGAQPQPQPQPTSQHQYGALQTGGPPAQNPNQGGAPNPANGITGNFNQYLPRGLAGNSNNVNVNGPQVQPPATSIKHSEQHRSSLLGMFTAKQTTAPAQPAPTSGSPASAPAPAPPQHATLGRPGQAGGVTTQRTVYSATTISTTQGQGPGPQQGPGPAQGQAIEAAARANGGPIEMNAELNLPFGALSLLTRPKAQQSGSPSHNAGHNGAHPSTFASPITELPAETNTRLRKQPSLPRQVSQVSQPYSTSPSERRPSTRGSQPPPAYNTVGSGAPAVTATLPSHGIVRRPSYASSSSTAPVDHQAHQAQPVHAIPALNYPPTAAATGGVSVRADQPGNPEHKQKLLSLFGGKPQQPPQPQAQPAMSASSAAGVAGTGLHPYAQHQHQQFPQHGQQHGGAQLGPFEAADSTRAVEGPGSRRGSSQTPISPANRNFLLGYLASVSSSGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3T0</accession>
    <name>A0ABR3Z3T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit SPC19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Outer kinetochore protein SPC19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SPC19</name>
        <name evidence="14" type="ORF">Sste5346_005554</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013251">
        <property type="entry name" value="DASH_Spc19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08287">
        <property type="entry name" value="DASH_Spc19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="123"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="196" mass="21175" checksum="E94CF7F7046CE18F" modified="2025-10-08" version="1">MSLYSSSASGSQTLALYGDCVASLRTSLAYLESSVATLAQETTGSPNGGGSTGAVADMPRLASVLKTVRHYELVPQPTLAAAEQSLQSEIGPAVAQLLDRASHQLARQARRIDTLQARAALQAGRLEGDGDSREPATKGRQLGRKTAPKNAVDPLRARMVHQRKEQLKYSVARLEREVAQKERELRQRLRQSTVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3U2</accession>
    <name>A0ABR3Z3U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribose-phosphate aldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase-C9orf114-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150:SF13">
        <property type="entry name" value="METHYLTRANSFERASE C9ORF114-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="37839" checksum="A82355CD3D4A28CF" modified="2025-10-08" version="1">MSYGDGFKRRKVEGDNTFKPSTRFMPLGGRNYTVSVAIPTSLLSDCSTSEQRINAPSRIARALAIFSIDEVVIFDDSPLDSRPPAVDLDAYTGDTDPGHYLFHLLSYMETPPFMRKALFPLHPNLRLQGLLPTLEMPHHPHRDEQLPYMEGLSLAGKPDNPAHKTLVDIGLRKPVSIAEEIPPKTRLTLHFPHESFEGASPVDPAAPRTEAGYYWGFQIRRCSSLSGVFTEAPYEGGYDVSIGTSERGEPASHVFPRGATPATDPPSLSFEHLVIVFGGPRGLEYAAMNDGELSSVGIKVANVREAFDHWVDVLPNQGNRSIRTDEAIFIALTELRRLWSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Y6</accession>
    <name>A0ABR3Z3Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-rRNA-processing protein PNO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PNO1</name>
        <name evidence="10" type="ORF">Sste5346_005629</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KRR1 small subunit processome component first KH" evidence="8">
        <location>
            <begin position="99"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="PNO1 second type I KH" evidence="9">
        <location>
            <begin position="180"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="271" mass="29382" checksum="A5CD82F363766054" modified="2025-10-08" version="1">MPAPTAAKKADAPVVQDVAQPITQDEVETLLDAAAAADSLTLTEIPAEKSTPILLGATDPGSDDFAAGMDIDEESRPKFAAAKDSETAVRREVRKIPIPPHRMSPLKATWSKIYTPLVENLKLQVRMNIKSKAVELRTSRSTTETGAIQKGEDFVRAYAMGFDVEDAVAILRLDGIYIQSFEIKDVKTLEGDHLARAVGRIVGKDGRTKYAIENTTKTRIVVAGGSKIHILGGFKEIGMARESVVSLILGKPPGKVYGNLRSISARLKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Q4</accession>
    <name>A0ABR3Z4Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="110" mass="11863" checksum="39CF565F969EA839" modified="2025-10-08" version="1">MTVTHIVLFQFKSSASAEDIQAGCAQFLNLGTACVHPTTQKPYVLSVQGGKDNSIEPFANGNTHGFVMTFATAEDRAYYVKEDPAHAAFVKTVGAMVEKITVLDFESGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Y4</accession>
    <name>A0ABR3Z4Y4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal subunit assembly or modification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SQT1</name>
        <name evidence="5" type="ORF">Sste5346_005555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="140"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="534" mass="55002" checksum="188C9A25653C356B" modified="2025-10-08" version="1">MSHSARDEHPTEDDGEDSGPEMLDMDDAAEEIEGGDAEDADVAMDSGDEDDNEELVLHNDSIAYFDLHKDSVFAIAQHPKYPSLVATGGSEGEGDDSPGKGYVIDTSAAVERPLLPASYSSDPSAASQPSSTELTPLFEIDGHTDSINSLAFTLPNGDFLVSGGMDGRMRVYGVKIGNGRADFKFVGESQEVPEINWLAPCPGRDYPNTIALGASDGSVWVLSIDPAADPANPIQIVQSFFSHTAACTAGVWTPDGNLLATVSEDSSLQVWDVWGVAAGRGLVPGGAQALLSLTGEDQRFEVPGGLYSVAVSPGGTLVAVGGAGGVIKVVTLPRLTGAQAAGAATKKSGAAAAKSAPAPKGAAGKGAAATDPAQFGTILASLEVQSDGVETLAFAPPPMTLLAAGSVDGSIAVFDVTRSFALRRHIRLAHDDFSVVKVEWVKSAPASLTGGVAAGVGGPAQWLLTSIGMDGVVRRWDLRKNVMPDKPGDNRLVKEWRGHRGDGEGGGVLGFVQGDTGERVVTAGDDGVVLVFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5J0</accession>
    <name>A0ABR3Z5J0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein SLX9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004997</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="216" mass="24238" checksum="8B8FB80B15891297" modified="2025-10-08" version="1">MAPVAPKMSHRAKALARIADPTLPRKVHREDNTVTDAFLHSKRDKQLIRKATFRARVLDKAGPTKKPLKRRRPSKKLVTTLESLADALPDVPSTNDAGEVEYDEWEGIKKRRRQQSLKTRPGSLKRKEKVVQAEMARFGQNLAQLTAVKEEVVQRDAAETTDGGMEVEKDGEKTTTETATPGDATSTRQSTANRFALLRNYITMTMEQNPAFAKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6A7</accession>
    <name>A0ABR3Z6A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13479" checksum="D1ABE6D3EA56EBFF" modified="2025-10-08" version="1">MLYELIGIARPGHLQEVRDIVLTSGQQILRNGGVIRSIANWGVFSLPAPLSAHQARHTRGHYFVMRFDCSVAAHDAVRNTLKLDPRMLRTGVVRLGDDRKLENTARFGEILWSQAFERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6V3</accession>
    <name>A0ABR3Z6V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine protein kinase</fullName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DUN1</name>
        <name evidence="8" type="ORF">Sste5346_004778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="232"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="323"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="639"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="708" mass="77557" checksum="563965644E6F61A2" modified="2025-10-08" version="1">MPRRPSVVISTLLTRLFRQQSIDAEAVDAKKPRRSGRISSQRVDSSYATEASAVTEIATPRTPAAAPPGARDKDGDKNNNKNNQLPTPLTFLAVDDSSSERRLKEPTATPPGGRPSQVAPRAGSSGSGGNGSGDEAGLYSSPPQDTQAMPSQYIDPNQALSDEVKDEVKEGVWGYLMPLGARYGSRSIVMKKRVGCDDDVSTASSSSKGGKKGGSKKSAGKNGSDQPSSKGYLIGRHPECDVVIDDPIVSNRHCLIFAENKGHDTIAIIEDLSSNGTFVNEALVGRNQRRELQEKDEIAVLDKARFVFRYPKTRVTSGFHQQYSLQDRLGKGHFAEVYLCIEKATGQRYAVKIFTKTPGVEDRSKTDGLQQEIAVLMGVNHPSVLCLKDTFNEKNAVYLVLELAAEGELFNFIVLNQKLSESETRKLFKQLFEGVKYLHERNIVHRDIKPENILLVDRDLHVKLADFGLAKIIGEESFTTTLCGTPSYVAPEILADGRHRKYTKAVDIWSLGVVLYICLCGFPPFSDELRSPEFPFNMSQQIRSGRFTFPSPYWDSVGDAALDLIDHMLVVDPERRYTVDQCMAHPWMNETPFNVNDSTDGLVGGVAGLAVNRRGLVRERTLISALNRVEITKIPGGANHDPIKIFNKNPKGGAARNGNGKEARPADNADPSAFMEHGDKGDPEIYGDESSVYSKTDVASKGKGKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7C1</accession>
    <name>A0ABR3Z7C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Sste5346_004590</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="21">
        <location>
            <begin position="60"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1896556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="57578" checksum="20A160FA86285B06" modified="2025-10-08" version="1">MSSQEKSEKGEGAVEVTPTGSEPSPSPSSPPSEHDHDHDHDHGHGRNGHEQTLDFPWSWKLTALACGLMLSWGSSFSENTLGPLKSTLVKELEISNAKYGAIDSATSLINTILPIVGGYGLDYYGVEWGSMACSVAIFLGAVVSASGSNRNSFDLVLTGRIIMGFGSTIIETCTSKILAHWFQRSGLGIVYGLDLAIGKLIVLIAKATAVPMRDATSFWGWALWIPAIVCFANLVQNVLYVWWVQTRPEWTRMPTGRRLARSANGGQRRKAGQAFLSFIVSVGRVLTLVPRIFWLVVCSQSLQAGVVGSFSSLNADIIATTRGSTAQIAGYTSAVQQVIPVVCAPLLGGFFDFYGRRMLIVSVTSGIWILVYCLIGFSHVNALAAMIIASVGSTMNALPFTCSIPLMVPDQTELGLVFGIWKAFNNSGSVIVDMIAGRLQDITPNGTYERVIIFFVSAKALEFCLGLFYGILDKKFLGGVLSFSQKKRVALEREGKLDNLVGRKPAKAFTIAGLTILASLVVVAWVLFIKYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7F3</accession>
    <name>A0ABR3Z7F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF11">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="396" mass="41962" checksum="055D9FE2769CBB6C" modified="2025-10-08" version="1">MSAVPKNLVVVGGSYVGVNVAQQLAAALSDSFRVVLIEKNSHFNHLFAFPRFASTAKVDTKKAFIPYMPGTFAATPGAHNNTVIQAKATGLTRTAVELDRPVSLTTGSTTEKVSSIPYEYLVLVTGTQMVPPSAMPGTEKREGVSYLQQHAAQVEAAQRIAIVGGGAVGVQMATDIKELYPSKQVTLVHSRPTVMNRFHTDLDAIVKARFAELGIETKLGSRVVSPLASTAAPADGTPLEVVSQDGSRLATDLVIVCTGQTPQSGLLASLSPSSINESGFIRVRDTLQVQDAALDNVFAIGDVADTGAAKAARPASKQATIVVQNIQHLLKNEPLDKYTGIDPAGIHMTLGLIKNIVFRNPHPGDKPHVVPREDGTYDMNIDGVWARRGGGIDANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7K3</accession>
    <name>A0ABR3Z7K3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Luciferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_005313</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF16">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="7">
        <location>
            <begin position="43"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="477" mass="52419" checksum="64CD91AC751A9AE2" modified="2025-10-08" version="1">MASTQNSGDSPTTPKKQLIINAFVESCSGHQSPGLWQHPDDKSWQFNSINHWVKLAQTLEAAKFHGIFIADVLGSYDVYKGPRNPAPAIVSGAQWPVNEPLATVPAMAAATRNIGFGVTVATTYEQPYHLARRLSTVDHLTGGRLGWNIVTGYLDSAARNLGHTAQPSHDERYAIAEEYVDVTYKLWQSSWRDDAVKLDRQKGVYTDPSLVREINHEGKYYTVPGPHICQPSPQRTPVIMQAGTSKAGKSFAAKHAEAIFVAGHSPAVVAKNVAEIRQSARDEFGRDPNSVKFLALLCPVIGATQEEAEAKYKEYVSYGSEDGALALFGGWTGIDLATYADDEELRHVESNAIRSAVEAWSKSVPGIAKWTKHTVANHIKVGGLGATVVGTPEKVADEMERWVREADVDGFNLAYALFPGSFEDVIEHLLPVLRKRGLFWDDYAVDGGTYRENLAGQPGQAYPRPDHPAAKYHWKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8V7</accession>
    <name>A0ABR3Z8V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Uricase</fullName>
            <ecNumber evidence="5 6">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_004290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the uricase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="5 6"/>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019842">
        <property type="entry name" value="Uricase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00366">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 5 6" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="294" mass="32908" checksum="CA85EDF51AC64015" modified="2025-10-08" version="1">MPHLSAARYGKDNVRVYKVHRDKETGVQTVTEMTVCCLLEGEIETSYTKADNSVVVTTDSIKNTTYIKAKENPVNPPELFASILGTHFLDTYSHINKANVSIKVHRWTRMVVDGEPHPHSFLRDGEETRNVAVVITRDGIELKSSIKGLTVLKSTGSAFHGYVQDEFTTLQETWDRILSTDVDCTWGWKTFANVAAVKENLPQFDKAWEDARNITIKTFANDESASVQATMYKMAEQILEAAPEAATAAYSLPNKHYFEIDLSWYKDTKNTGADAEVYAPQSGPNGLIFCEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAD0</accession>
    <name>A0ABR3ZAD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF3">
        <property type="entry name" value="CUPIN 2 CONSERVED BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="86"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="183" mass="19934" checksum="0DC89403FBE52D35" modified="2025-10-08" version="1">MAGNSGMRPVKRFITTHDANGKTTFDTSIPEEAPFKVLPDGAEFALCYATNGFPVQLNDGKDLATYDHYTKNLPGVTISTGTVLRVVNIRPGSTAPMHRTVSLDYGVVIEGEIELILDSGAKRLMQRGDMSVQRGTNHTWRNTSDTEWARMLYVLQPAEPVVLAGGQVLTEDTHSIPGVRSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAH5</accession>
    <name>A0ABR3ZAH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">NineTeen Complex (NTC) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CLF1</name>
        <name evidence="14" type="ORF">Sste5346_004276</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059164">
        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF3">
        <property type="entry name" value="CROOKED NECK-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="10" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="13">
        <location>
            <begin position="59"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="12">
        <location>
            <begin position="212"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="12">
        <location>
            <begin position="319"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="612"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="671"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="674"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="709" mass="84068" checksum="8846CA6D60B8D013" modified="2025-10-08" version="1">MESRGPPRVKNKAAAPVQISAEQLLREAVDRQELPLQAPTTRFEDLEELHEYQGRKRREYENYVRRSRTSLKPWAQYAQFELEQKELSRARSVFERALDVLPNSVPLWIKYIEAEIKNRNISHARNLLDRAVTRLPRVDKLWYKYLYVEEMLGNVSGTRQIFDRWLKWEPAEEVWNAYIRLEKRYNEYDRARDIFRSYTIVHPFPRTWIKWARFEEDFGTSDLVREVFDTAMESLGDEYVDEKLFMSYARFEAKLKEYERARAIYKFGLDNLPRAKSMLLHKEYTTFEKQFGDREGIEDIVVSKRRRQYEELVKENPKNYDVWFDWARLEETTGDFDRIRDVYEKAVAQIPPAQEKRLWRRYIFLWLFYALWEETDAKNPERARQIYDTCLGLIPHKKFTFAKVWLQKAHFEVRQGELTAARKTLGRAIGMAPKDRLFKGYIELEKKLFEFQRCRTLYEKHIVYNPANCGTWIQWAELERGLDDLDRARAIFDMGVSQPVLDMPEVLWKAYIDFEEEEGEYERTRELYERLLERTDHPKVWISYAQFEINIPEAGADDDEEEQEEDAPVSEEAKARARKVFERAHDSFRDKELKAERVALLNAWLAFEKTHGSEEDAAKIQKQMPRRTKKKRRMEDGSFEEYVDYVFPADDRQAKNQMNLLAMAQAWKKTGGTVAAAAAPEPAAASEDSDSASSRSVSPVSSRGDDRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBI3</accession>
    <name>A0ABR3ZBI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome p450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003908</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF96">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE STCB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="57549" checksum="70CBE4A1BA092CE2" modified="2025-10-08" version="1">MAMFQISFAGWTCLALAIVCVIKYYILTGKRMYYVHSLHETYGPVVRIAPEEVAVADPEGVAQIHRIGGGFLKGPWYTGTNNAPEPGIFAMVNPKDHAQRRRLFAKAFSNASLRQNWEPTIQDKVKLAVALIKDDAQRGEADMLKWWTLMATDIMAHLSFGESFHMLELGEKTKYVRVIESALASSGIGYELPWLYAIARWIPAEAIQVVVNARNYIIEYGGKAVDNMRKQGGSSQNLFGNMLAACDDGEKQHFTDLSIRLEASNLLVAGSDTTANTLTYAVWAVLKKPDLQRRLVAEVGALGPRFGDAELEQLPLLNAIIEETLRLYGAAPGALQRTVPRGGATLGGHFLPEGTMVETQAYTAHRDPNFWPDPLRRRHAHRRAQWAWRAARHHGTAPEHTALPLPTTATKRARPPTADSSTLASSPLPRPTSDVIVVSGSPRRSPTERSRTAREPKPTAPSTPSGHNATPATPSTPTATTRTVHPATAPHTTAVPWDVATICGILDSHANDPTAALVLQRRFPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC44</accession>
    <name>A0ABR3ZC44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24477" checksum="BDD196207DC4208A" modified="2025-10-08" version="1">MNCCQRALRAAGLRLGRPTQSFLSSTASRASARPTPPHSLPRATAVWPCTSFHSSALARRQPPPRQASGAANPPSAPRGATDFNSLDIFGDTPVPSTSVDICYDDGFKLNSGLQTVDGSGVMLVGGEAFSWRPWGKKTSLVNAKGQFEVDTSAFDLLSLVWPRPDLLILGLGPEIRPLGPSTKKYITSLGMRVEVLDTRNAASQFNMLATERGVDDVAAALIPIGWKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCK7</accession>
    <name>A0ABR3ZCK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flavin-nucleotide-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071">
        <property type="entry name" value="5-NITROIMIDAZOLE ANTIBIOTICS RESISTANCE PROTEIN, NIMA-FAMILY-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071:SF2">
        <property type="entry name" value="FLAVIN-NUCLEOTIDE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="31239" checksum="1271FAE6E3E27290" modified="2025-10-08" version="1">MSKLEPATLRRYQERGLYDVASAKAVFDDSFIAHVSYIDDGYPACQPMLTLIREEEVEGDETEGDAEGETSETSGLAPRKTAYAYLHGHPTSRLMELVKKAGKDAEAEEATNGTNGVNGVNGNGHAAEPVKVCITATKIDGLVLSSAPNGHSFNYRSAILHGTCEQVRDKALKKQIMHEVTDKIVPNRCAEVNPMASIVTSMVYIIRVKIDRLSVKARTGVPGIQPRNVEVDGPNVEPLAWAGVVPMWEQLGEPVDAGLTPGASVSDNLKNFIVERNAKHAAHAKRVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZET5</accession>
    <name>A0ABR3ZET5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA mismatch repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MLH3</name>
        <name evidence="3" type="ORF">Sste5346_003295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="504" mass="54364" checksum="F177BC1AE01E15A6" modified="2025-10-08" version="1">MSIQRLPGAVAAQIKSSSTVASLNATVLGLLRNSLDAGASRVTVSVDYSRGSCAVEDDGSGILSVEFEADGGLGKLYYTSKYPPSKSVHGRYGTFLASVADLSLLTVASSSSTNGFESTLAIHNGKVLWRHASDSSDKTSVTSPSDQDEGIWIARLLSQAGICETTDPEFWVSIGASVSGVRVSGSVCLEPSASRKAQFLRIGVTPLSEAHQADELYGQINKIFTESNFGAADLANSEDPTTRGPMDKFVREQRPRKAVDRWPMFSIGIDLDGTASVDDVLNDRRQYMTIISGLIRTVLTEFSKAHGFYDAPEVLYGSDYSSGSTPGSPSKKQKTKDTANLPTTTRAKHKHQLPRRSKDTQSLFSTWPQTKSAKSAKAKQVQLADAGPEKETHEDGIVEEQNWDGNTLTSGDLKISRASLESAKVIGQVDNKFILIRALAVAEEDGEAGSLLVLVDQHAADERCRVEELLQNHFAPSIEDYSSPGEAIRSILTRPLQFELAARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG94</accession>
    <name>A0ABR3ZG94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="838"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="923"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
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        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
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            <begin position="319"/>
            <end position="331"/>
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        <location>
            <begin position="332"/>
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        <location>
            <begin position="359"/>
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        </location>
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        <location>
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            <begin position="441"/>
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            <begin position="457"/>
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            <begin position="490"/>
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        <location>
            <begin position="924"/>
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        <location>
            <begin position="948"/>
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        <location>
            <begin position="1009"/>
            <end position="1019"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1029" mass="109603" checksum="3DEC877F548A390B" modified="2025-10-08" version="1">MEPTRGRPPSAGKPNLFSSSGGKVITKEQKRSSSRTSILRRLSMSATNVLNGAGAAPGQAPAPAAAAAATARADNAGRSSTQIGRQQQRQQPTETAPTSSGGGLMSFKKHFRRSKNKPLFDSSNNGADTGGSEGKGSGGRRGSGTANAPMLSTGSETSPENGTKGGNDAASDADSESGSESIIEPYDSAEYDTGSESIIEASRSAEDNTGSLDATTTTGSPITTADVVSTRTPSFPKTDERTTGSENSPSDQSPPHKQAQQPQQPQQQPPVTFVVPGPPPPVPEKVPEPANVIALPAVPPKIPAPPPPAGAPTGQMAPVQTNNVNNIGGANSTQTSQSVQSLQAIQRQHQERQQQQQQNATGRVSSPTKTAKETKEKSGGLLGGFKKLRRSDSKRGNLDPARPQPPPQAQAATTTAPGASKPTTVTTPTPAERTASTHALATNQTASQVQVAQTTVLPPPPPPIQSPPGGNRGADIDGVPSSLRPGGGQPVQQHRQHQQQQPQQQQYQQQYQQPYTQQQQQQPQPQQHQLVYEPAPQQTVVVQQQQQQQQQQQQQQLQHQHHQQQQTPCDSCKAYYEAAWAQSEINMYALSSQLAAAHQQSSGQVALLHERDAEIAELNGLVGRLRTRIQEQVKQLEQLPAGLPGLNTMSGLNGYAAGGVGQLPDGQIRSRWKGLRWQIRQCVEARLAALPPSSAASVPVSSERAPFLRRLTPDFDKFLHSRKGSVYLVEAAIWAVLSDSVFSGARRSSRMCWAARWSTSLAKMNDNMMYSRSTDPAFHQWRVQTAVFVRSLETAAEGDSQQQQQQQQQQQIVAAPYVEAVVRQLEVEVGVLLALGTGGPSGVEDASNNGPTGHKESSTPSPPTSSSSSSSVLRRQLYDVVAEAIGLDADLCQQRAWFYVHYPTSTSGQRYGMPFDAREMEPVTVTSETASQSSGGGGSETHLGLAMSGINSSSSNVNNSVGSSNGQHSSDEISLVVRPALFKAGNSRGEGYDQTLTIEPSIVCQTTPSGRGFRRWAAGGRRDRSRSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGE9</accession>
    <name>A0ABR3ZGE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22794">
        <property type="entry name" value="THAP DOMAIN PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22794:SF2">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="811"/>
        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="KAL1899783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="838" mass="89875" checksum="5E6BA1E95552364E" modified="2025-10-08" version="1">MDRATSAGSSARQSKRMQLVQSSSGSDSGSGSDSDSGSGSEHVPKRQPPPPTPPSRLARQASDHQTPQKTQKSHEHHQHQQQQQPHKSTSSAGAPHTRTKAQKHVVGGGGSTARLHARVPSSKALHKTVHHHHHHASSTKLQQQQQQQQQQQLQQLQQYQQQLQQQQHQSHHHRRRSSTSPPTTPADYAARFPFAAAPPPIEQSAPSQQQRPQPHRRSTSTTESNLKRSANSASTSSLVRRNQSATSLLKRNRSHADVAKRMSHGGTRSNTNANIKRVNSNPAVNSDRLRPLSSAGKKKSSAGGGQVHFEIGSPDAQDQEDEWVDAGSSNVSGSRKNSLQYRHEESPKSHRSPSKPTKEESEEEEDDSESESESESEEEEEEARSTKQQPQQQQLKLPIRSASGSQQTPQSQQKQQQQQSTKDNQAEAHPSSSASTVASSHLRTSSSTTRLLLPRTPPRGAPPKMSTETVSATRNTQSSSPDSSPSRRLQHRHQQSLPGGSGDRDAMTSRFITTGSHESAGGTTGGDSYYTTSSSRPSTGRQLDAGTSSGGPSHPRRTHSIGGETMQQQLTDDEDSSAISGGDVRKMTSAALPTGGPVSTHPRRTRAPHAPPAELSRTQQKLNLERASSNIDRGSRQHAVPVAGSLVGAGEFGMHDPRIGKLMEKTGMEYYMIRRYQNPVTRSLSRLTDRLGGDRNWRIPAANGGISRASTGLSDTPAAPGHKATASASGLSQSFRERDIRRGVLQSAAAAAAASGSGANAGGAPRSGKPYVLNGNGAGSGSASGSATPGEAARTSFQQQQQQRLSGASLVEGYDEDSTASILRNLWDKNLYLGTSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGZ9</accession>
    <name>A0ABR3ZGZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bud site selection protein bud4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BUD4</name>
        <name evidence="6" type="ORF">Sste5346_002841</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR012966">
        <property type="entry name" value="AHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08174">
        <property type="entry name" value="Anillin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <begin position="1181"/>
            <end position="1302"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <begin position="1036"/>
            <end position="1066"/>
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        <location>
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        <location>
            <begin position="849"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1355" mass="150737" checksum="50A3C0358606D220" modified="2025-10-08" version="1">MASSEPKLGLNADSSPFQSSPLDSTTSPRLFWQNRNGFNTENLYGGGIGGSPSPTRRSSIERLQKASRVKNSSILAQEQKNEYDPTKIPRVERPLSKVQSNSFGSLSFSASLEGNEVKGHQRRESKTDIPLYNPAKTSPSVVDIDSPPHIPGQLSASIQSDKSDTPAAPAADSTPVMASKEPGSPIKSSLSSRFKSSYDEHGDFSLDASVGEYELPLGRTLHRHAKSVTFDAAPPQVNEYEMATPDLSSVGSNSREGSYDSQDDEDDYDDYRYSANDHGNPDDSFDASLEDTDKTPVVGPDDWRQDSPDARRGHNMYDSSPMPDAVPSSVVGHQDVKSSLGSSGDHRPLPPLPGMGHAHTNSATSPSLSATAERMLGGSPRGLPSPPPAAVSKSEMQNIGNSKMTLEERLKLMMLSDDGKSAAELQRERRMRRAGPKDRANSQTPEPESSQRDAASEHGEEEDTIGDLSGLEEYRLPPRISRESILRRVNGAVSHERESDYNFSSPAPSSSPERRLPLDPDVPIPSTERDDDDNISVDDEACEKHNEAYDIPDMYDDDDDEDDDAEDYESNYSEEQAGDVAQPTHADGVSTPRPATPVQEISSHTVTVDDIHRSDLAAIAQEGRISLGETRLPLMPKSNDGNANANHMQPPNAEVELARPQTPERKVIQHKHLSKPEYDGSGWGDDEEFDDEPGTPDSVIHHPVQDDEDDIFEDEQDEEDAEMEAYEPPAVPDQMATIKASGSKLKTRPSATPSDLVAMREARRQVSREVPDVPPIPDRHRNRLSRDMGREDLEGTGDDFLERHPSFKKRSLTLDLDLGLSLDKDFERVIENQKRGYLMRQNTKLVAASDKEHGEDFRGARSAGNSPVKKERPQSWTVEPWNGERRKSIRKRGVPSSGPVPPMPGQESNATALNPLTEEEYVAETTTDEGAERGRLFVKVMGVKDLDLPISRTERTWFSLTLDNGVHCVTTAWLELARNAPIGQEFELLVPNDLEFQLTLNVKLEKPVQRKVVQASPAKVVRPKASTFSRVFASPKKRKEMELRMKEEDERAAREQQEAQAKLRNAAPTAYDLLSPIVAEDGSFARAYVCLKEHESRCYGRPGIVEIACFNEWATEEAGFASSVKSKRGNMAVVRRAPYKIGKLELQLLFVPRPKGISNDDMPKSMNSCIREMKAAEERQSQNWEGHLSQQGGDCPYWRRRYFKLVGTKLTAYHEATRQPRATINLANAKRLIDDRRALTEKETTGKNGRRRRSAFAEEEEGYMFVEEGFRIRFNNGEVIDFYADTAADKEGWMKVLSEVTARDSYGSEDDLTASRAKTKWCELVLKREEALRRRVEGRSEGGRRVHSRTKSSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH74</accession>
    <name>A0ABR3ZH74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_002964</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="27851" checksum="C6B693DCF154CCEA" modified="2025-10-08" version="1">MASTTLSVIVTGAAAGLGKCIATEFLKRGWQVALVDIAADKLSAATEELRALGHQGEALAVEADITNEESVKAIFDKTVAAFGQVDALVNCAGIMDKFHGTGEQDVALWNKVLDVNLNGAFLLSRLAVQEFLREGRVVRNGDATGEVKTGGAIINIASIAAFRGGAAGVAYTASKFAVLGLTTSTAAAYARQGIRCNAICPGGMATSIAEDFDYSNLGQLFSSVMKINEVSAGLSDTGRLARLVAFLCGEDGQDISGAVIKVDRGWTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHP5</accession>
    <name>A0ABR3ZHP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="504" mass="56148" checksum="454DAE47985A99BD" modified="2025-10-08" version="1">MGEMLFIRAAHAKEAWSGNSITMSQTISTRPTAPSPPIKITAVGDSWDNITQTKTTDSSNTTTELLKADNEDCLEETNVKEPPPQLNTEPDTQQHDVVSSESRAQISPEPVALQSPSPLLRLPLELRLQIYRWVLLLGTIDRKPEAGSSSSEAAKPANDAASSVSVSSTLFHCMPPYFFDSPQDFGPGDGIMFMSMFASNAHQRPLFFRKVLMPTQDNGKKKEKTDYAQLLPAYRPVGRALPLGVMSSCRQVYQEARTIAFKTSEFVFVRLFCSGLSTAHAFVVLGSQTYPGTVGGDIPRLQLWQRDSLRHVRLELDVSVADMGWTGPERDPKYLTAGENQEVKKEGPKIIDGPKWLAFCDALAKSLHGMRVLLNITEERHQGMAEDAGEKEDDTKEEYISEEYAMAARSIVAQGFTRLAALRQLEIELVWVLRGRFRSRAANMTPASTRNNLMWCTAVETAINEARRKRSETESPESSTLRPVSTKVICVERIYDEEKKKEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI41</accession>
    <name>A0ABR3ZI41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002887</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="203"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="350" mass="37691" checksum="8E50CCEFC82DD27F" modified="2025-10-08" version="1">MASPIKRRVLAPLDANTPVSASPMSVAGKPAASESKLPLSPPSSAIAKKRTLPETSLDNETADSTTPLKKTCLASESRIDASPTSLPRDTKQQAQQEARQVPTSTSPVAAIVAGSSRPSLSPTTSSVFDLSAMVDTSQATNITEPDVEAPRPTLAFTREQSRQRAEILKLRLSLARYKVRTGQVDVPLEQLRVVPAATLQQRQQNREWSASEWVRQQQQEQKHMAGSLAGSSQPRQQPPLPQRWALWGPASSSTGGAPGSRGRDQAMSVSQTSSSDEEEDDEDEEGDLPQLPQIRRLSPTKKWTSRHNLLTTPRGNRLLVDDGDGSHLDGLTSSAMRGSAVNGLLSLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI49</accession>
    <name>A0ABR3ZI49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="40"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="363" mass="39744" checksum="D351FC8EB2756A52" modified="2025-10-08" version="1">MTTKLTPDDARVAHHTAAIRDKTYHYIVANPPAGQAAKGTIVLIHGFPDLGFGWRNQVPVLAEELGLRVIVPDLLGYGQTDAPEEPVQYAYKSICDDLVALVDHVGVVGGGPAGEADESKRFFVGGHDWGGAVAWRMALWHADRLRGVFSVCTPFFAPSKGPFVPLADMTKLLPNFGYQQQLAGDEVYSFIDAEPARVRQFLQAMYGGQVKLSEEDAAAKKSPYLFDTTNGVHLDRLAGVGPSPLLSPAEIEYYAAEYARHGLRGPTNWYRTLKYNYDDEREIVESTDESRREIRVPSFMLSATHDAALPPILAEQMGKHFTNLTKAQVPGGHWVLWQSAAAVNEQIKGFLAPLLDGTAKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIJ1</accession>
    <name>A0ABR3ZIJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="154" mass="17527" checksum="0F1470E4ED7A0C97" modified="2025-10-08" version="1">MSTAPPSAEPDNEDAASLRASQRLLEYAGRAALQMPELEVLEIWQTYTHEESIFRYDALAEPGPTVTFLSRFDMEPMWTKEAQTAWEAAAQKHTDNQKSLVVKYDTLDPHPDHFHGTFYIYGTINKLKLRDLVIDPVSLYAATWEECSATYITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJX1</accession>
    <name>A0ABR3ZJX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="9">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CCT7</name>
        <name evidence="11" type="ORF">Sste5346_002238</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="526"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="558" mass="60879" checksum="8E30426FB438092F" modified="2025-10-08" version="1">MSFGGQTPTIIVLKEGTDTSQGKGQIVSNINACLAVQATIKSTLGPYGGDLLMVDANGRQTITNDGATVMKLLDIVHPAARILVDIARSQDAEVGDGTTSVVVLAGEILKEVKEHVEQGVSSQIIIKGLRRACTMAVNKIKEIAVNTDEANRRETLSKLAATAMTSKLIKRNTEFFTKMVVDAVLSLDQDDLDEKLIGIKKIPGGSLTDSLFVDGVAFKKTFSYAGFEQQPKNFVKPKIVCLNVELELKAEKDNAEVRVEQVSEYQAIVDAEWQIIYRKLEAVYKTGAKVVLSKLPIGDLATQFFADRDIFCAGRVAADDMERVVQATGATIQSTCSDILPEHLGTCGVFEEKQIGGERFNIFAECPEARTCTLVLRGGAEQFIAEVERSLHDAIMIVKRAIRNRSIVGGGGACEMEVSAYLHQFADKNVPHKQQAIIKSFAKAMEVIPRQLCDNAGFDATDILNTLRVEHRHRGHTWAGVDFTHEGVADMMERFVWEPALVKINALQAATEASCLILSVDETIRNEESQQPQAPGRALPPGAAQRALRGRGRGMPMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK21</accession>
    <name>A0ABR3ZK21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar import and degradation protein 27</fullName>
            <ecNumber evidence="5">2.1.1.221</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vid27</name>
        <name evidence="5" type="ORF">Sste5346_002250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="266"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="454"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="840" mass="93443" checksum="D5A3167A5930D184" modified="2025-10-08" version="1">MFVLRNAAKLLFGSGSQESMIELPQGQLYLVRPLSPKGYSELLFKDAAARIRRTAQDFQYQLVVQRVYEEGEAELLADEEGEDAEIDPLAAERDEKTFLLDEALEFRVEKRDQDSAEHVLCWRDLTGDAGDVYEFVLDRSTTHAGLVHQFELAAKQCQYERKYRKPYTTATDEDLAQFEFAGKLIPPASPLHSPSLARSIASTDSMLAGAGVGTTVIDTPTKAPAKTPAKTPAAPPTDETPSATASAGTAAAALKTKVGEAPEAKEILTAELAELHFFDFPSGSFVLQDASVTAIVSETGKWQYWLQVASKDRDWLGVPVVADINPVFNFEFLSFIFNQFTADGTAYSWLLRFKDQATLERFQEGLLRALWEQLNEVKWSKIKEKERDYVADAFADLAMTDVPEEEEEEEEEEEESHTEEEDEDDEDDDRPRSEHYDSDEEADDVNLQPRDKAMNKSLAVGYKHDRSFVVRGSQIGVFKHTPQNQLEFSTNISKIETPGGKLFSPKKVMLHNEDRNMILQNDTDPNKLYRMDLEYGKVVDEWNVHEDIPVVTFAPENKFAQMTHEPTFLGVSHNALYRVDPRLAGSKLVDSELKQYVSKNDFSALATTGKGHIAVASNKGDIRLFDRLGINAKTHIPALGEPILGLDVSADGRWILGTCRTYLLLIDALQSSGKNEGRLGFEKPFAADSKPQPRRLALTPEHVAQFAHETGKGVTFTPAKFNTGEGTEETSIITATGPYVIEWSLKKVLRGSKAPYMIKRYRDDVKADDFQYGTDKNIIMALPHEVNMVDNKSLKRPTRESIAGAALAGAGGGRRSGGRISGVNSGRYKLGKDDVVNSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK26</accession>
    <name>A0ABR3ZK26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase 2</fullName>
            <ecNumber evidence="5">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GST2_2</name>
        <name evidence="5" type="ORF">Sste5346_002140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="116"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="280" mass="31547" checksum="89EEB2ABFD58DED5" modified="2025-10-08" version="1">MSPTPTNIVAYLAQVPDCVKIAILLEELGLDYEMRLVDVTKAEQKEPWYLEINPNGRVPALTDILPDGKELKLFESGSIMQYLVDRYDKNHKQVTSRASPIVLLLTYLPSVSYPAGTLENYRTASWLYFQTSGVGPMMGQAMHFTRFAPTTIEYPLYRYRTEVNRLFRTLDTALTTSTSGYLVGDRCTIADLALWPWIVSDFWAGVSVDAYPNLKKWEQLMISRPGVNNGRHKPGRHFMKELAQDPALQKTIEKAGGEWIRGLQDANAKKGNVTIGAGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV3</accession>
    <name>A0ABR3ZLV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002191</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="8">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="9">
        <location>
            <begin position="134"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="265" mass="27827" checksum="61D6911D270514FD" modified="2025-10-08" version="1">MANTVITMLPNSAAVNTVYLHSDNGILAGARAAERDPTTGQPYKKLIMECGTIETSTIMSVAKATQDLSASELSQTLTFVDAPVSGGPMGAKSGTLTFMVGCAPASADEVYPVVKSHLQHMGNADGIFLCGDVGAGTSFKVINNYLSAITSLAASEALNIGVKAGLDPKLLTNVINVSGGQCWVTSKSNPVPGVQPNVPSSRNYEDGFRIELCAKVLGMGTDLAKMVGARTILDGPTQTAFQEAMSDDRYKGKDARVVYKWLNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLX1</accession>
    <name>A0ABR3ZLX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PRS1</name>
        <name evidence="13" type="ORF">Sste5346_002205</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF57">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="12">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="230"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="513" mass="55271" checksum="A24698A81B7B6703" modified="2025-10-08" version="1">MRNTQIFAGTSCPALTQQICENLGMAPGDTELGQFSNGETSVRILTSVREKDVFIIQSGSPKINDTIMELLIMIQACNGGSANKITAVLPYFPYSRQSKKKSHRGAITARMLANLLNVAGVKHIVTVDLHASQMQGFFKCPVDNLHAEPIIARWIRHNVPDWKHAVVVSKNAGGTKRVTSLADALKLNFGMVTTDRRRNNNMTASMIMTHLDNIEQKAPVVSTIYRGAATPIHGRDSPLANGSRGGSANLNGAASSSSPAAQSANGNGPTSHATEPAPPRTPSEASTADTIPTAPNDSSLGQSSEPDQEDSEYNDQRAHEVTHARLFQGHIVPDDFPSPAVSTADGSVVEEDPMMMSHISSFFQPEPHALGGSGDAGASDSEDDEVLPAKPNVERMVTLVGNVRDRAVFIVDDMIDKPNSWIAAAETVVKRGKAKKVYCIATHGIFGGDCLQQMQDCDCIDAIIVTNSYPIPPEQARDISKLVVLDLSYLLAEAIRRNHYGESMSPLFQHIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM06</accession>
    <name>A0ABR3ZM06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="60220" checksum="1C273B754EAADFA6" modified="2025-10-08" version="1">MSLAAHPVVAFAADRPSPAPRILVMPSWSDTAQAPRGGRSRAGLDSVIPAPLQPLVRAYLLGYASSVGPRLLTVLLTYFTALRRKRRGLPLAQSEKASFAYLRDSVQHILRAGLEWRRFPTFCATLVGGSTLLEIPFRKLLAQLAPKLSLVARTRLSRWLAAFVAAYGSLCLLQSKQTPGFTETAVVTPDTSAATTQANKTSKTGDTKAATANSSATPTTITIPYAGRTLDLTLFAVTRALDVIVGELWARRKARRVAVGSWSGLEALIGRLTDPTIFSASSALVMWAWFYVPSRLPHAYNKWITSAAAVDSRLINALRLCRDSRLQYGKDMGLDARLLEGMSRDYNWPLSWGDPAVTIPFPCTMVHMDCGPSCERHAMMRMWRSWRWSMATYLPLSLLLVLRKPYRNPRGVLRAILSAMRSSAFLGAFITLFFYGVCLARTRIGPLILGKSVAARQMIDSGLCTAVGCGLCGWSILVERASRRKDMGLFVAPRALATLLPRRYSLDKQWRETLVFAASTAVVFTAIQENPKRVRGVMGGILKTVLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMR9</accession>
    <name>A0ABR3ZMR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase family domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052765">
        <property type="entry name" value="PGM-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46192">
        <property type="entry name" value="BROAD-RANGE ACID PHOSPHATASE DET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="74942" checksum="127DC9761495C36A" modified="2025-10-08" version="1">MGKPRLLIIVRHGQSEGNKNRDIHQTVPDHRVRLTSEGWQQAYDAGRRLRTLLRADDTIQFFTSPYRRTRETTEGILQTLTSDNPEPSPFKRNNIKVYEEPRLREQDFGNFQPCSAEMERMWQERADYGHFFYRIPNGESAADAYDRVSGFNESLWRQFGEEDFPSVCVLVTHGLMSRVFLMKWYHFSVEYFEDLRNVNHCEFLIMRKQGDSGKYKLESKLRTWSELRRERAALLKQKEELEAAKDKTTDKTDKTLEKGDKDSAKLEKAASGLSSSSPSSSTLVPQRRWGGCPNGCNHDKNFKIRPGLADLIKRDGTNVYDSPNSGSGSSPRSSKLTSAINSHSHSHGKSSATPPSLSRRVTAVRRFQVAGYSDDDDGGDGGDEVDDDNRPSSQASNDTNNDAASKSPKEPLIGGSGSGSSTKLAANNKSTASAGGGLVPPHIDITRAREEIVSSPDATPSFITPEDRQRTVSPGGSPPPLPKPFLHIGRDFGGTYSGHTSDADSSEDDRVRYRMARLKMNIGGTAESGAQHSHSHGHGHGHGHSHNHNHNHSHGSVQFYGTLDAVAATATSGKAEVIAAVATGQLERGSATPGSAGGSSSNLSNIRKKRTKNMANRLGDAPHCSDCEHDHGDTTDLGADELDMDDELLSSGVVVVDDNGDDETDIDPDLALAEKEDKSIQGSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNN1</accession>
    <name>A0ABR3ZNN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="538" mass="60409" checksum="289305D9C30AE0B0" modified="2025-10-08" version="1">MASISTTAIIPPPLPPISSTTNVHFPCRQWVTLDAKWTLTLVVTAELAWDQLGSTPNSTNPGVFRNKRVAAARVVELVRAGRLWIDSSGRRVDLVVRPMLGGMVVGNSHINSEDGVDSVRELFHETILEWPLWEDKLGLRVRSRSAESAEMRPGDDTTLLYFTVNHPPSPSGLYAPSRAGGGIPQARLERVFCQLNINYCAEGFKIPRVVPAAKKSKVKAKPTSKSKSKKRARPSKPKKKPTPRSNLRPRQSEAACRQQQQMVDGPRNELVVGSPAWRQATALIMMSLHVLMGTAGKTPPVPGIRPVDDVSAPSGAPSLLDVAPAVWSNHYFTTIERPPDLIDDDDQLIDLCFDNLEAIFSQSQDDNEGPPREWGDYMEGDTDDEDDIEAQELDWGDIEALPEHYEYGADNYEINEYLEEEDGLFEEIDETWSPQDLVYDESQEMEEGQSQQDPYGSQQDPYGVDLSEDEESGLQLWQEMQAWQLDELQDDEESQPMCYDLGYMDDDEDIRFMDIDEADLDEGIGLCRDEHDIIERIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNV2</accession>
    <name>A0ABR3ZNV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13214">
        <property type="entry name" value="PH-GRAM_WBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044852">
        <property type="entry name" value="WBP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="28534" checksum="843758AEE0A7144C" modified="2025-10-08" version="1">MDFYQEQHSYTLASNASVNSDDSDEDASWVMMSRDGEVVKLPGEKIYYKVIYVPARPTETFKSFSAPILDFEDTRVASSFFGPWSWNAIVKPTIGGGIPSDVPRLELKLTFKEGGHDAFQNKFEVMKERLSYARTLQQETGQVIPTGEDLPQYEPPKPSGPPATASSAATATTTVGEASRASDAKEREALDHFSQSHEQQTPRTAQADLLGATLQQNNSRNQPSPIMPDEPPPDYEEAQAQAIGNRFEENTREAADQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP21</accession>
    <name>A0ABR3ZP21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-amino acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DAO1_1</name>
        <name evidence="8" type="ORF">Sste5346_001434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF16">
        <property type="entry name" value="D-AMINO ACID OXIDASE (AFU_ORTHOLOGUE AFUA_5G11290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208327" evidence="6">
        <location>
            <begin position="18"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="391" mass="42042" checksum="ACCCBD951EA8108B" modified="2025-10-08" version="1">MPNIVVIGAGVAGLTSALLLARDPKNKVTIVARHMPGDYDIEYTSPWAGANVLPMSDAPGSQWEKETWPELRRLAAEVPEAGIHFQKALVLRRPKKAPVADSAAKAPVLSDALFDEDPWYKTLMDDYRDLPAEDVLPGYASASDFTSVCINTALYLPWLVSQCRKHGVILRRAALKHISEAASYAALEVQKDGTTAKVEGLDHSETIVVNCSGLLACRLGGVMDSAVQPARGQIVVIRDELSPMLASESVVGEYGSLPNMEIIYNMTRAAGGGTVVGGTYQIGNWESQPDPNTALRLLTRIAAEHPTLVAAGKTAADLSVIRHGVGLRPYRTGGVRLESEQFDLPKSDGEGKFWVVHNYGHAGWGYQGSYGCSKRVLELVREIVAGKAGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPM0</accession>
    <name>A0ABR3ZPM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cysteine-rich transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_001053</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CYSTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028144">
        <property type="entry name" value="CYSTM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12734">
        <property type="entry name" value="CYSTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cysteine-rich transmembrane" evidence="5">
        <location>
            <begin position="87"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="58"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="125" mass="13375" checksum="DB76854C13F87E5E" modified="2025-10-08" version="1">MANKENPPAYPGSPQPPQAAYYGGPSGGGYNNSRPYQQGPQMGYHNQQQGPYGGQPQYGGQPQYGGQQPYGQPPYGHQQPYGQPPAGYYQQGGYQQQQQRSSSDGCLTALLGTAACCCCLDCLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ89</accession>
    <name>A0ABR3ZQ89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_001237</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="350"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="517" mass="55465" checksum="36D54E4A4976A832" modified="2025-10-08" version="1">MKSLTRPLTAVSVKSTASASLAYRSSSSFSSSSLSSSVSTVSSPARLRCSLPTPLVAIRSLSASQHRRYSSPPSSSPSPSTSSHDDLPPLRDEDIVRLAKEPQHQLRLADLVRHGWPPLGEKALLQSANFSLELIPVRLARRLQALRNLPYIVVSNSHVRQIYRNYRHSLRSLLPWWRRRHDKGPNGGPAITTLDEEIAFTDVLAELVTTHQNTIPILAQGFLESRKYIAPADVTAFLDEHLRARIGTRLIAEQHIALHLSSQPFSSAPANGGGQADTNAQAAAAAASSENAPPASEASSYIGIIDTQLRPARTIDSCAGFVADICELKYGVRPQWRIDGEPDTTFAYVPMHLEYIVTELLKNAFRAVVENKMHREPVVITIAPEPSGGGNGSDSSSSSSILPLDDNASGVTIRIRDRGGGICPEVLPNIWSYSFTTFSDYDDLPAGTSPGGGGDVSDGLNIIAASNNGGSSIAGLGYGLPLSRAYAEYFGGGIAVQSLYGWGTDVYLRLKGVGNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQW9</accession>
    <name>A0ABR3ZQW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="327" mass="33938" checksum="1DF025BC500D5B49" modified="2025-10-08" version="1">MGTKHLTEADRLRARTLFFDAGLPKARICQITGFSLNQVKLAIREKTPKTRSGRPPRRRPGASAAAAGSTSGAAGEASMGGIVQGVDGSEVVGEHDEHGGHGEQGEDGSLMMAHSTAATPSPAMDEAAAGAANPTHRPGDRMPSVHHYGQQPQPQQHQQAHQAHQQHQQHEHHQQYQQQHHPQHHGHHPTKWEPEYHHQGPYYASWTQPAPNSPNSVVGGPRGPATPASPPLPPPTASVRMLATIAPLGIPSSYASAKGRGDVGVGSVGSVGSVSSRDGRSSDGHDFSSSTSSSSLASSATSYSSMSSSASGGGFSLPSILASATGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQY4</accession>
    <name>A0ABR3ZQY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001614</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18833">
        <property type="entry name" value="GH43_PcXyl-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF17">
        <property type="entry name" value="BETA-XYLOSIDASE C-TERMINAL CONCANAVALIN A-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045916519" description="Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="6">
        <location>
            <begin position="446"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="656" mass="71820" checksum="1376EEFDD12FBA4C" modified="2025-10-08" version="1">MPAIRTIVRLLAVLPVVVAVTPHVNSTTSFTNPILPGFHPDPSCIHVPDDDGNSNSPGTFLCVSSSFSAFPGIPVHASRDLQNWSLVGHVLNRRSQLPALVETNRSTSGIWAPTLRYHGGMFYVVTTLVHDERPQTDASRWDNLIFASDDPYDDGSWSDPVHFNFTGYDPSPFWDDDGRSYIVASHAWQVKPGIQLAEIDLDTGEVVGSNWTTIWTGTGGLAPEGPHIYRKDGYYYLLIAEGGTGVNHMVTMARSRTLAGPYTPNPANPVLTNANTIEYFQTVGHADLVQDAKGHWWAVALATRSGPAYTNYPMGRETVLTPVVWPSSHGTYKNETAGWPHFSPIRGTMSGPLPPVDKEFNSDDDDATNEADDDGYSGELVGDDLSFAKWHTGKSLPPHFTYWRPPIKSSYEIVPMPDADHVNDNTTWHSSSASATTKNINTLRLLPSTLNLTGLDGNYAGPSGQTFVGRRQQHTLFSFQVDLAYQPITSREDEAGISVFLTQNHHLDLGLVRLADTTPVPNGTTEYRSNYVYLRFRGITSGDAAVAHLPQDHSVMVPSSWHIAGTGSQFRNDASPLQVTLQIQAANATHYSFSAWPTRAPVEKMTIAWANNDAVSWGFTGALLGVYCTSNGGNASKAAPVYVHRWQYALLGQVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR18</accession>
    <name>A0ABR3ZR18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="298" mass="30568" checksum="2B397B4DCEDCD720" modified="2025-10-08" version="1">MTSYPTAEDEKRLLAHAAETTTTTIAADNQKSQCKHACRRRVAKAKKVVHFTVTLAFVFACCIAVFGLGSLAIGTIRAARPCNKHTGAHGKAGSHHKNGAAVVVAEGAVPTGSSFSRLLEAVSPESLHDLLHEYLPDTYKHGVYPSEKHALEAIHRENAALATSIIQLARRDLNSTTSSSSPSSNTPSSTTSSTTSLPATSTFKNTSTTSHITSKTTSSSSEKTTSSGKKTTNIYTSTVNGTPTVVTATSVVGVSAANTGGTATNGGTLQTGAAAPLAAAGNNARFAVAGVLVGAMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR73</accession>
    <name>A0ABR3ZR73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome c oxidase subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome c oxidase polypeptide VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">COX6</name>
        <name evidence="12" type="ORF">Sste5346_000468</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00923">
        <property type="entry name" value="Cyt_c_Oxidase_Va"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1903183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="151" mass="17032" checksum="C04C7274D3AF75F5" modified="2025-10-08" version="1">MSASIFRAAARGLRAPLVARPAAMATRTAFVQKASFSAGARLRSEHQEETFEEFTARYEKEFDSVQDVFELQRNLNNAFAYDLVPSPSVLIAALKAARRVNDYPTAVRVFEGIKAKVENKGQYEQYLEELKPLKEELGIVLKEELYPEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRH9</accession>
    <name>A0ABR3ZRH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mind kinetochore complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_000580</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007128">
        <property type="entry name" value="PMF1/Nnf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15459">
        <property type="entry name" value="POLYAMINE-MODULATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15459:SF3">
        <property type="entry name" value="POLYAMINE-MODULATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03980">
        <property type="entry name" value="Nnf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="30346" checksum="85DDEC234AD67C55" modified="2025-10-08" version="1">MATHEATATASSGATKKDKTTTTTTDTLSSGQQPPVGDSDEVLPDADDQGVAESGDGTSAQTQPTAQGQSSQSQQPPPPPPPPPGPRAGRLQALFASSLDHTLNKISWDNFAACYPTAAAKSPQALKTVHRAMVDRLGELCTAEFAVVMRNRDVVRRLNELETLSSDAHKRRLAAANSGSTAAPSPPHTLPAETVLAAHLAPQRKAQRQMLEERLAAVQAANTARFAKLTAQQTEAGQLVAALERALADAEGAAALLDGAAENGHGGDALDNTLVAELARETRAAEVEMTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRM1</accession>
    <name>A0ABR3ZRM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tfs1</name>
        <name evidence="13" type="ORF">Sste5346_000349</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="12">
        <location>
            <begin position="153"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="270"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="85"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1903065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="312" mass="33468" checksum="1FC61F5BE7791B81" modified="2025-10-08" version="1">MSDKSIERELTTRIKALNKAVTSNEPVPGILAIMETLKKGAAPSEEVLRSTKAGHIVGKLRTHANAEVKSMAAEIVSKWRKAVEAGKKKGGNSGSSAAPSKTASPSASTPQSKTASPAPAAGGSSSSGGYKGDPEKRKYDVDGVDVNRTGIQSRDNCIGLMYNGLAYRSVEASDKILVKAIEVEKAAFVVYKGETTEYRAKLRSLFQNLKNKSNPALGRRVVAGDIAADAFVVMSSDELKSAHLKKLESDLTKENMKKAQVPMAEKSISDALTCGKCKQKKVSYTQAQTRSADEPMTTFCECMVCGHRWKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRU5</accession>
    <name>A0ABR3ZRU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BRO domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BRO1_1</name>
        <name evidence="9" type="ORF">Sste5346_000787</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09242">
        <property type="entry name" value="BRO1_ScBro1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09237">
        <property type="entry name" value="V_ScBro1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF30">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="8">
        <location>
            <begin position="5"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="561"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="785"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="728"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="564"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="788"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="819"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="897"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="938"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="961"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1006" mass="111868" checksum="3DE6DA1A691D4C5F" modified="2025-10-08" version="1">MVQAPMISVPLKATNEIDWIVPLKNYIRDTYGDDPERYAEECATLNRLRQDMRGAGKDSSSGRDLLYRYYGQLELLDLRFPVDEQHIRISFTWFDAFTHKATSQFSLAFEKASIIFNISAVLSCHAALQNRSDESGLKTAYHSFQASAGMFTYINENFLHAPSADLSRETVKTLISITLAQAQETFLEKQIADQKKVGLLAKLASHASSLYAQAAEGVQANVDRAIFEKVWFYFVQIKASLMGSMAQYFQGLADDDANNHGIAVARLQVAETLGKEAAKLANSFPSTLPSSANLGADTSTLLVDITKRHLTTVQEKLRGFNKDNDFIYHDTVPDAASLSPVAKLPACKPIPVSELYAGQDIQRITGPDLFAKIIPLSVTESASLYDEEKAKILRAETERVDTANSEMAASLDYLRLPGALQVLKGGFDQEVLPDEDFRTWCVDVADHESPEAIFEPLRRQREAIIATLDKNAKQLDMEESVCEKMRSKYESEWTQQPSSRLTTTLRGDIKNYRDALDEAGNSDGLLATKLRQNSAEFDEMRTAAQHGEVDALFQRALAKVRGKSGSQTTSPSEGNLLDTDFEDSNNPSVPDQINAVDDILSKLNLVKRERNQVLKDLKDKIHDDDISQILILNKKSIANYETQLFKSELEKFRTHQNRLVQANHKQAALMKELTAAFNTLLQDKRVRSEQSKYESVQRQRASVVNKYKRAYQEFLDLEAGLNGAKRWYADMKETVDSLEKNVETFVNNRRSEGAQLLNQIEQDRSANKGQQAELERERLRGLMERMSVEPTPSSSSTPPLPSSSSGGMSGRPVPMPLHLSNNNAPRYPATNFTGQYQVPQSPPPNQAAMPSPYASSFGQQAAAYNPSAHGRIPGPASPPPNMTTFGMNAMRGPASPAPTQTTFGHSGGNQYSTYGNQQAQSAQTPHSATPSNFVPAGFVPPPPPRAPPPLGPQQTYHVKPTDYYSQQQQQQQPSQQQQQYQQQYQQQAPPPQQTQADPWAGLNSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSA0</accession>
    <name>A0ABR3ZSA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dimeric alpha-beta barrel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_000191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1903563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="29285" checksum="AAE0BBB179167531" modified="2025-10-08" version="1">MANPNRTDYEGPELSGPGILWINSKVTDPDTLPVDKFTRWYEDVHIPDIIAARPGGIISSWRYQCADAGREAPFLAVYKCPNMGFIQSTEFKSIPMTHPTLPDNGPIHRYADFDARFLKHVETWSSPEATDGRTATLVSEAIEPATDLSADAFNEWIRTEHIKEVASLPGWRRTSRFELVFKKENKDDPNSTAKITPHYLALHEFASNDVVPASGAIGAFPPQLSAASKAILDGARKVDVAAFSILRGFGDVGTRWVDTEEKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSI3</accession>
    <name>A0ABR3ZSI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_001445</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF77">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="19"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="513" mass="55348" checksum="3E2C4B1D45A9752E" modified="2025-10-08" version="1">MAASPPTESILSQWRAIVICLIAAMGAFQFGYDTSYFSGILVMDAFAEHYGTFDAATGAMVVSASRQSLVTSIINVGEFVGAVTAFWIGQSIGLKGGLLLACIIVVIGTTLQVAGTALGLLIAGRLVLGYAVGLISNFVPLYLADCAPARVRGAIVSMYQFNIGLGLIIGVCVDYSTKERTDTGAFRIPMAVQYIFPIILSSGLLLFCPESPRWLAAKNRIDDCTAALRRLKGPDADVQADAQAIVQMLHQESLAGEGSSWRSIIKSSVELRKAYLGCALQALQQGTGINFITGYGPYFFTVIGIENPFIIQVTLYVVGIPATWISQYGIEKMGRRPFLLISGIPMAAALMIMAGVGLNLQEANPTLAASRTVVAMVFVYMIFFSFGWGPTVWVVCSEIATGHNRNKLMTLSTSTNWFFNWLVSFVFPYLFNADAANLQTRVGFIYGSLTLAAVAWVFFLLPEPAGRSLEEIEFLFESRVPARKFSSTKVDLSANAEGEAPKAVALADIEHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSU1</accession>
    <name>A0ABR3ZSU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquinone biosynthesis O-methyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinol 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.64</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Polyprenyldihydroxybenzoate methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.114</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">COQ3</name>
        <name evidence="8" type="ORF">Sste5346_000638</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol into ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-methionine = a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="2.1.1.114"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:81215"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:19654"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:231825"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.64" evidence="5"/>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EC" id="2.1.1.114" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="7">
        <location>
            <begin position="149"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="346" mass="37536" checksum="ABF9D85543A63945" modified="2025-10-08" version="1">MAHPRAAAPILRQACRLRPSAPKRSITTAAAAAQQLSSSQRTIPRASIATTPTASRSRHHSTASTSTSSSSPSSASSSSPSSSVSPEEIAHFNALASTWWDPYGPSRLLHQMNPLRHDFIRECIRDGAFFDPSTTSVKPIEDILPRTYLDVGCGGGIFAESAARLPTTKSVTAIDPSAEVLAVAQVHARRDPVVFERLQYRQMSIEDLAASSEGQQYDMVTLFEVIEHVATDPGAFLDRCGRLLKPGGWLVMSTMARTWTSWLTTVVAAEDVLGIVPRGTHDWNKYINADELEAFFRPGAPAYTSATWQNARFQGVAYVPGLGWKVVPGGEKLGNYFFAIQKADTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSY7</accession>
    <name>A0ABR3ZSY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transaldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105">
        <property type="entry name" value="DIM2-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105:SF1">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="935"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1058"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1218"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1309"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1541"/>
            <end position="2068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
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        </location>
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            <begin position="440"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
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        </location>
    </feature>
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        <location>
            <begin position="570"/>
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        </location>
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        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
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        <location>
            <begin position="850"/>
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        <location>
            <begin position="1111"/>
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            <begin position="1231"/>
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        </location>
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        <location>
            <begin position="1659"/>
            <end position="1673"/>
        </location>
    </feature>
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        <location>
            <begin position="1674"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1718"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1744"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1798"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1850"/>
            <end position="1860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1861"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1899"/>
            <end position="1913"/>
        </location>
    </feature>
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        <location>
            <begin position="1915"/>
            <end position="1949"/>
        </location>
    </feature>
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        <location>
            <begin position="1953"/>
            <end position="1964"/>
        </location>
    </feature>
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        <location>
            <begin position="2032"/>
            <end position="2041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2055"/>
            <end position="2068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2068" mass="222631" checksum="2574B22D4A03B6BE" modified="2025-10-08" version="1">MGGDSKKKKTPIPLPAPTESESIITAPTDVATATDVSRPGDEKSSYSLPEDGTPVTIKTRGHSANRSQTSLLIEYFEGGKSPGGSESPASRRPSVRVRLKPSGSRKDERIMISKNKSSSSHPRKASLSRRSSTPQKGSSSAARDYDGAGGSAISALSSGGDGEDSRSINSYASATEESNVSRNPITVEIDHGSGGNGGVSASNQQRQRQRRPTSPLIPAAASSRGSASYLHGTVSEISAIPADSFLDGSKSPRSSSPTRDMALAAAATAAGAAGAAALERHRVSSRSRGDDPDRIVVSKSRSSRDKDRDRDYDREKDRSGRKHRSSRSRTSSLNVAEREDAGSPSQRRPSRHRHHNESAVSAGAESSVLSSALSPSHRSYDQYSIRSGASKASSINNPKLLETVEDAIRRLILPELNALRREHSHRDRRSSTTSTGTSVSRDEYATNDRRRSGASDRHGSASHTPRDKGREIRDREGRHALVDSPSPAVDYASDSELGATTRNIDDTPKHGTDKVRDAAIAAAAGAALGGLATAAMTGHDGSPSTARDQRRRRRAEAQQGKEVDRGQALPQGQQQQQQQQGPPDLYLTGAHSAASRSFEDQTQGQRNLHEVPIPPGGGGLNAGQLQHLDPDAGYLQPPMPLMSEINSDMTRTSILSAESDPPLSAEEERQIPPVQDVSRGTLPGGPQGSLPPQYTTSSGSLQGLGTQHANISHGDLRALPRKAVGSGSNYQHMTDEGIDEEDEDSVIDREHQYPDQYLQQGGEDEYVEDYDSMADYAGQTYDAYGHQIVPAPLKYVPYQPEHRGLSPIPSVSGYTEGGTSEVQGYRDSGVTTTSTSSPGKSPRIERKSAASLNSIPSNVMSREFEPDDLSVRSSDVDYRPAPTQLTDVTDDGDHDNFRAVDGIATNPDITHTPIGVESAVASLVDGSMLDGSALTTSSSADGAYAPVSGTRGSMDTLEEEQSHGQTTPKNRSVESHDQTLREGDAGFREREELHEAREIAAATPTTTRTNPSEFSGEYEIDQYGRKVRRASPTASEAAAITAGAVGLAIRAARDRNQHPYQPHEDREIHEASGSQNVPTESEWVPAGVQRNKSFKERTMDGRHPANTPTHSTDRLDEYDHEEPHLGASGLPDLSNPIPEIGYGGYSEDEDMETNPSVVHGHIPDEEQDEQEEDWRAGNRTPTQGDRTPTQERHDDATSHALGLAGAAATLIAGAAAANNMHDASQHSRQVSQERDDEWQRSSDERKRDTLITNPYEGTSPVVNEGLIKKSIPNPASGAAAAAAAAAAAAAYGMTGPDYASRSPLGGRYDEGYISQGPGKSPELTNVNKGKGIDYTDAPAAFGAAQEDPFYTTNQTRHFSGLSQGMATPLYDPATGAGIDRIENKDIVALMQHLMVRDAQRSARDTEILVTLVRAAAEMRTSFENVRTMLTMHEKGINNEFSKKLADSEDAIITEILDGTEKTVRTHLGGPRPFPGSGNRSLHASISQAEMEDLPGKRQNIFRRALKSLNTKGNNDLTRIEDMLNQLLNQVDVLKAQSAGGVGPGGMSMSGSASGHGPSPYDEAQMAYEQDRGYEPEGQAGTSTTSHASQSGLLSVNSRGGLIQSTRKFSDNRISTVPEGNEDELEYNHGPPGDAPGSGAAENMGAQGPSGNVRFGSPASIPQMSTALMATPTRQSQDIQQQQYQQSQHSEPQLQQVQQTSLSNENTPRTEKAKKHKSSSSSSWFPKISRWSETTTSSVGRVFRGSRDSKKDHDELGFHSSLSRSGSDLAAYDGYEPTPEDKLHTGFSETDIHGGNYLDRSQPQIQSNRQSHEGGQVYQQNQYDDDIHGYHLPPDSTEILPPNPKSYMTPEDPKYRAHRDSLNLQHPQPRSGQPFKAALESQAADFDSPMSPRSADWAGSATSLNRFPGQNPNRYSDASASNAAAQGAQQQQQQQYWDAGAAQGSQSQSGPPRPPKEPLDAERHQQTPPRPARLTKASKTSPLPYHSVESGYGTATHVPTSYTGSPRFENRNLSGALTVPTRRPSGPRAMTPKSERSTRSYNDEEPGSDPRRQKRNTFGTIASQETDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTE9</accession>
    <name>A0ABR3ZTE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phenol 2-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_000309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF7">
        <property type="entry name" value="P-HYDROXYBENZOATE-M-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="422"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="71410" checksum="74AB0B7C4B81DF9E" modified="2025-10-08" version="1">MTSQSVPHYDIVIVGAGPVGLMLSTLLARWGYKIRHIDNRPEPTATGRADGIQPRSLDLLRNMGLKPAIMAHKPARVYEVAFWDPPKGGDGIERTGTWASCPSFIDARYPFTTLLHQGLIERAFIADLEKNNVEIVRPWTIKDFTSDEASNPEYPVEVQLEHIDGFAQETIRAKYLFSGEGARSFVRQKLGIQVRHKDPISYVWGVMDGVVKTDFPDIKMKCTIHSREGSIMVIPREDNMVRLYIQIASSTDPDFNPRKTATEEEVQDYAKKILQPYSIEWERVEWYSVYPIGQGISDNYTLDHRVFMGGDACHTHSPKAGQGMNTAFLDAQNLAWKIHLVEAGFADRSLLKTYEFERKEVAETLLSFDNKYAKLFSQKPPSASAVAAANESESAPSAEAQSDNAFIQTFKESCEFTSGYGVKYQPSVITWSPDHPAQSPNIHPAGNKLRPGRLLINADVTRVVDANVVHLEQEVPSNGSFRIFVFAGKSSTTAAALRDLEQGLHKRNSFYAAYQRQDIAQVSHHEKHNPHSLFYTFCIIFAGRRQDVEISRDVPGLLAQYRGHVYADDQWNRRVPDATASAHAKMGFDQERGGVVVVRPDGYVGIVTSLVEGSGTLDALNAYFSSFCTKKLSQESAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTN5</accession>
    <name>A0ABR3ZTN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="250"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="387" mass="42809" checksum="AC997554D0F23BC5" modified="2025-10-08" version="1">MSASFMAALADDLETETDEVTRGSCVSSPSCDSIQIHRSNLAVDLSGRRVSSRGAVTSTANSQTDDLTTAFPRLVVTEPACVTNDAPSDAEYAGRDTGADDKVQWTTPETQQDGLETGTGSLALDIQQRKPFHKWVKALNRRRITRWHLRRLEKSDQTRSETSNRASRSSVSRRNSSSISSFAYVSAARDASISSAGTSIAPSSRRQRARSSKRLSKTDRSSRASCSARHSEDDRLQTQDDLDTLERSRHRRRIIEEMIETEEGYIGDVKFLMKAYLMLFASSSLVDPGFRLSMYSSLTDIIELHDEILGSLHRVVPNSEYAGIPRMSSAYGYSATKIRRRRSLDVVPEDRTKGLPLYEYSGLSAEPHTAAAVANIFTKIVGSSNYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUN7</accession>
    <name>A0ABR3ZUN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription initiation factor TFIID subunit 1 histone acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_000244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 1 histone acetyltransferase" evidence="4">
        <location>
            <begin position="463"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1050"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1903615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1137" mass="126132" checksum="1EB49B73219FE824" modified="2025-10-08" version="1">MPAAAENERGFTALNEDDWKRTANEDDEAIMSLLSGSQQGTEGGGLPADLLNIKFSQEGKADDAEDFEDISDDDLPEEEEGTSGASADLPGLTDDAGTSHETDDLFGDDLGSPTHDDPFPPSPGAQDDGDNKGKDGGDAAAGSKDKADDDMDDGRSDQAAGRSPSPTNNDPYIVTDSDRALNFPEDYGHDTTNQDPNIPPVAENLMDLVKMAFPSFEKGKILNFNEQLAPKPLYLTEKKPAKPPKPLVPTKLSLEFEADQEKLFRIPGTAQATILQRVNDAAARGFVSLLQPEAQDQDNGNIFRDPFGDEDDDENTPIGGFLLKDFAIACADWDDITGLPTPPPEDNSSMALVRAEKHKRAAGSDEQDEWEREILGSAAAGQAKRRKVIAEPGLPVLPRYVAPSFDSFQEATARAAKRVYLDMADYRLLLDDGENDRDPKRAKLTAQKRLPNGRLVRNLASRFNYSNDQAYEQLKENHQHRVRAQHSNIQVEHSLPALKLLWPYYAITRYGPEPHDYHRPQLKVNKGMGFSVHMAKLRKVAKREWKHKKIQETFARSKDLSLGDNSTAVLFEYCEEIPTVLSNFGMGNKIINYYRRKSKGDEEKPAKPELGELSFLLPEDKSPFSNFGTVDPGEMVPTLHNPMSHAPIFKHQSRPTDFLFGRTHSSQDGTSYYLRKIDQLFVVGQTFPLAEVPGPHSRKVTALSKNRLKMVAYRMISRNGSVSLSDITAHVKDSNDAQNRQKLKEFLHYDKETKTWGLKANDTLMDLATINSMIKPDEVCLHDAMQVGQNELSQNGYQLDDSAALDDVDDENDKESLAMNMVPWKTTKSFIDACAGKAMLQLHGAGDPTGRGLGFSFIRTSMKGGFMGAIQGPSATSADAMERERKANNGHMYNVKKQDALYNDAIRKIWASQRTTLEDDTPHDDEDVQPQDDEDDRFNAAKEAPTPAAAAASHVVHADDSVSQFSKPSMSIAPEKRKLRIVRTYRDPKTGQAYTKTEIVHDAGVIAQYMRQRASLDMEKIDPYSVKPTGNQDYDRVLMQRLETEEARLNRNKERRHAREKQKALQQQIHDGDPDSPAPSIERGGTTRKCANCGLQGHIKTNKKLCPMLNGQWKTDKTAEEGGFGVYNAPDSLSGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZVZ9</accession>
    <name>A0ABR3ZVZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-serine dehydratase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_000242</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="3">
        <location>
            <begin position="340"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1903613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="504" mass="53468" checksum="26790843D8DD0233" modified="2025-10-08" version="1">MDPRSFIGKRLGDHEIPTPAAVLDRAVVKRNCSNMLAAVQNMNLGWRAHIKTHKTIELTRLQVGEELPVQLVVSTILEAERVLPLLKSYQTQTIPAPRSVNVLYGFPLYAAAIPRLAAVARELGPGGMSVLIDHPDQVAIAQRLAQTADTAIRAFVKVDMGTHRAGIILGTPQFTAVIQRVLTAHAAGEGLSFYGLYCHAGHSYDAREPWAALAHLVTEFTALGDAAESVRTIAKEMLSPTAAGAQFLPLVLSVGASPTAASLQHPDLGGKGEGDAQDPSAAVNAARNAATLRAKLNDLGSQGYELEVHAGVRPVLDLQQLATHAWGGGSNGRAETDDLALTVMADVASIYPGRGAQGGNEILVNAGCLALGREPVKDAPIVSGGGPTYTGWGIVKPWNTDTGKPESGSRVVPPGAEFPRLLPADGSEGWWQVGRISQEHGILTFAGGPAPSVPFLQPQLGQRLRIWPNHACIAGAGFSYYLVVDSLSENPDEVVDVWERWTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZW99</accession>
    <name>A0ABR3ZW99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA polymerase II transcription factor B subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TFB1</name>
        <name evidence="10" type="ORF">Sste5346_000302</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13229">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027079">
        <property type="entry name" value="Tfb1/GTF2H1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013876">
        <property type="entry name" value="TFIIH_BTF_p62_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12856">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08567">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BSD" evidence="9">
        <location>
            <begin position="161"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="BSD" evidence="9">
        <location>
            <begin position="241"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="567"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="657" mass="72184" checksum="DE13496CC8AABB23" modified="2025-10-08" version="1">MVPVQGNAAYKKKEGILAVSDDHTRVTWTPVAGGSPVTLATANITNLQQTPDSVPKVMLKIFEKIPGTEGEPTSYLFHFNSPTDARSQANVVKDLLSRIISDSRVNDPSLPKPISAAGTPQPDAGTPSSTGKAKASDAGAGLSAAMSFANTVAAKPAGERWFDDSQLKVDIELQQSLMKKEKALHQTYMDAQKSKPESISDAAFNSQFWSTRTSLLRAHAIETNQKKGAYNVLSTIKPKTVDGELKLNISLEQVQMILNQHPLVKRIYNENVPRISESQFWSRFFLSRLSKKLRGERVLDSERADPLFDRYDEADDTIASSLILSSHVPHIIDLEANEENQGGFKSGNRKDKEMRPRSNIPIVRTLNSLSEKIMATVAPSDQDPTTSTQADVDAQEELTLRDLRGDVETNRIILNVREQSRFFSDNNATSSQDQAVYEKQVPSEVLFDVQADIDTLEGDGAGGIDLHAGLGIDEESESDDENTQRADHVGSRAARQAAQKQVLAAVSQKRAELYGHSSDEQTPMGIPAETAQKAYITNATTTEFLKQFWNAFLSGDPDRAQELAYHVESLARSMARIEAVADEAEEARNKFIEEKKEEIRVLYGKTGRRIKWRPEMIGGGRKAVCVLLGPTISSLETAQNLYKAALAAEGLKPSTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG99</accession>
    <name>A0ABR3YG99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type 1 phosphatases regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YPI1</name>
        <name evidence="5" type="ORF">Sste5346_010280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the YPI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000126">
        <property type="protein sequence ID" value="KAL1887341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="202" mass="21192" checksum="9A6D5D8B7F69F543" modified="2025-10-08" version="1">MASIPTRQLLSQEPQAAASGSRTITTTPGPSSAPGVSSDPEHQQEQPTAILRLQGANTRDSRNVQWAEGVVDNEGMNRKKSKVDESSNDSSSSDSDSSSSSDEDSDDGRATRGDADQAFRGRAGGANNNRRRAAHHRHAPDCPDHDHDDSGMGSSSDEEGPSGGSGRPGNNKGKGKGKGKRRPSPNAYEKVPRYGKPSTNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGB0</accession>
    <name>A0ABR3YGB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010275</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000125">
        <property type="protein sequence ID" value="KAL1887365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14474">
        <property type="entry name" value="SPX_YDR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="385"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="531" mass="58229" checksum="04169C7543E3CA28" modified="2025-10-08" version="1">MKFGRQLESESVPEWSVHNIDYNTLKEFIKVHTTRHQASAITIPGQKDTALQRFESEFYDELCRQHDRVGLFVATKADEINRRQQHLSDQIHRLLLRGTTARGTTALKRQRRFAKYERVTLELQDEIKDLSRFVNAQVVAFRKILKKYKKWTGSGALTFRFRDNVLSDPKSFTRRDFSQLEGHCDDLLNILRASTPLSSSPQTPREELSVPDFPDSHSRRASNSGQVCSSSSSTVQALSSSAGSNNPPAPQPRPASEGRRLTLLASAPVQTHYWNEYDDGSEAGDVGNAGSGGYAIYLHPDDEEDFPGMATLVSFFTVPLEKAKKWMASRSSKGGADRGPLLSQSAGFPSYGTTLGSGGNDDGLFDALSRQERNETVEIHHDGSNDDVDHDSTEEDDAFASDSDFPRGYEAHYAALPSINDQRIARYRETMLIRGTIGCYAAALVLLGVASILIETGKHKLRVEVDAGVIMGVMASLGFTCAALGMSMARRGPVSMASTAAVWAAFAIICALNGAVLVLVMGNTVITNTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGM8</accession>
    <name>A0ABR3YGM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Carbohydrate-binding module family 18 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000138">
        <property type="protein sequence ID" value="KAL1887180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045988420" description="Carbohydrate-binding module family 18 protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="8">
        <location>
            <begin position="30"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="8">
        <location>
            <begin position="113"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="8">
        <location>
            <begin position="202"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="8">
        <location>
            <begin position="280"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="334"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="388"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="443"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="497"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="518"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="58727" checksum="0C771F4C2E2CA352" modified="2025-10-08" version="1">MNLYNRSLLLASFVLRLARGSSASTVTCSLSLPASTGDTCASFAAEWGLTEAAFTALNPSAVCPNLVAGTSYCVIGTVVTTTATTTTHATTTTTTTHPASPTSTLPTVVDCTLSTAASDGDTCQSFALEWGVTATKFESLNPGVACPGVLVAGQSYCVVGTVVTVSVHPSKTTTTTTNPSTVVWATGAPSPIQSGLTANCTNYYFVASSDSCSTIEARFNITTAEFAAWNPAVGTTCSNLLPNYYVCAGVASSSTTTTQTTSTTTPAYPKQTGIAPNCDNYHLVVPGNHCSTIELQYNITAAEFTAWNPAVGADCANLFPGYDVCVGVRPFSTDGKCGAASSVNATCLGSTYGDCCSSAGLCGSTPAFCGGRLGCQGNFGACTPVSTDGKCGAASSVNAMCLYSKFGDCCSAAGTCGTTSAFCNTFEGCQPDFGTCVTPVSTDGKCGAASSTDATCLGSKFGDCCSSSGTCGSTPAFCGGRLGCQAKYGACTPVSTDGKCGAASSVNAMCLYSAFGDCCSSAGTCGTTSAFCNTFEGCQPDFGTCKTPVSTDGKCGAASSTDATCLGSKFGDCGHLWYYIRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGQ1</accession>
    <name>A0ABR3YGQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_010190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000118">
        <property type="protein sequence ID" value="KAL1887491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="64"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="60174" checksum="3370437B345EFD53" modified="2025-10-08" version="1">MSSVELPKLAIAHVETMTSQKEANQEVDEIATKKMSNGPEILESAFAHMDFFRLVRLFWRVNLIALLSLSGALFDGYAQNLPGSIAANSSFIKTFGTVSSATGAKALNSQYVSAWGGITSGAQVVSMVVGSFLSDRFGRKFNMYSVTFFMAIALVLELTAKNWVYFLMARGFAGWATGIAKTTLPCYVAEIAPIGLRSALLTMFSFWYAMGQFAVAIALQIIQQHGYSWRNAFFSELAFFGIFIPVTIFLPESPWYYAKKKQHARAKASLQKLNGAVPGYDVDHEYAVIADEVERTDALQQKQAAVAWIEVFKGANARRTYVSFLPLATQQLVGSALIFSYLSYLFGLAGVKNPFLVSIASSTILIGFLIIASCTIDKVGRRPLLLTTLTIVFLCNLFMGVVGTLAMKNDNLFTESQSAAAVALSCIWVAAYAMGPAPMGYAYLADTSTPVLRAKTTGFASALTGLFALIFNYSTPLMISTQNAGWGIRVGYFYAPLSFITLVLTYFTVPETTGRSFQELDELFENGTPSRKFKQTKTSVQLAEERAAGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHB7</accession>
    <name>A0ABR3YHB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-hydroxyisobutyrate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000133">
        <property type="protein sequence ID" value="KAL1887242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF81">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="3">
        <location>
            <begin position="6"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="4">
        <location>
            <begin position="179"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="33617" checksum="C9479314C925E819" modified="2025-10-08" version="1">MATPIKLGFIGLGAMGFPMASNLIRNSAKGSQLFIYDVSEASLKRFSEKHPGSTVICKSPAEVSKSTHILFTMLPEGSHVKSVYLDPVTGVLHDGMTAKILIDCSTIDVDTPPLVLDELRSRHPSVSFFDAPVSGGTLGAEAASITIMLGASEQDPLYPMLLAQLSLMGKNIVACGGPGMGLTAKMCNNYCSGLIALATAEAMNIGIRSGMDPRLLGRVFSSSTAQSTICDKWNPVPGVVPAAPSSHGYQGGFKVQLMAKDFGLAMQAAEKVEATTLLGPAGLETYRKAAQDPNCRDLDSRVVFRYIGGDEKWQDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHN2</accession>
    <name>A0ABR3YHN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000110">
        <property type="protein sequence ID" value="KAL1887732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="677" mass="74038" checksum="4B64BE25BCF8B34E" modified="2025-10-08" version="1">MPFEQTITIINNSGKIISTGKHLVGIFKEARSAYKEKKDALRQERLSGIHRARTFDVSRGGYYHGPNFEVEECDDGRRYGQDDGYRRNHRSLGSGPVPLYLENRGNARRLSLDDGDRRSQATSDSRRRRRRPHRSHTSDDSVSNAAGSSRRPPQPPLTANNLRALSDVFTIRPPSAPQSRRDGRGLYAEPPRHDMVLSRPALDRPAAVHPSIYAPVVPSEHSEPPTATFPSPRASLMVHRPRSDPALGLCAGEIDDIGGVPTPPKPIDMNLAYGSIPPDLALRTDLDPDGFVAGEPDAVKESQARTLVDRIETLLNEAQCIHHTAASIICHLQDNPEAAAAVALTLAELSALLAKLSPAFLGVVKGGSPAVFALLASPQFLIGTSIVVGVTVILFGGWKIVKRISEVRAVREEEKQAFEMGSPHNGPPQQQQVPGTESQEAFAPAGVPLLPSQASTRSYDEALVLEEELSTIETWRRGIEPTMEGDSGTEPWSSSEVDVELISPEAMRSRIDDDDQRTLKSTRSTRSRGHVSSRGGQHRHRQKHHQHHQESTQTGSRTREPEGKPEVPQRQSGRVFKSVETGDSYHSARSHHGDEEGSESGRTTASRSSRYSRRSRSGGDRALDKNGSSGPSSKASTTRSKDSGKPNTGSNMLKQLFKMKRSKDDKERKEGAVSALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY3</accession>
    <name>A0ABR3YIY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000096">
        <property type="protein sequence ID" value="KAL1888278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="5">
        <location>
            <begin position="72"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="203" mass="22633" checksum="058D400981A9026F" modified="2025-10-08" version="1">MALGATKNVVTDFDDEYVNTLLNVKVEIEYKAELELDRTLYLCPYGQDKSTVVTQASHGVAAVSEKCGRAGARQEPEALTKAYVDRARLMVSRDKNRPSVVIWSLGNEAFQGRNFQAMYDCVKAYDDTWPVHYEEDVDARISVGTASSCPWWTFDLVRGWLVSLTKPGNDEKGETTSVQILHMGPALSIYPDQTDNDLTVGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ03</accession>
    <name>A0ABR3YJ03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_010245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000122">
        <property type="protein sequence ID" value="KAL1887404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045003207" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="39"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="383"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="519" mass="55871" checksum="A474D101240D2783" modified="2025-10-08" version="1">MVGLLKAAASALAFGPLLASAGPVSLDRGSSNFSIEAPLVVKTSSGIVHGAINESVPLTRHFLGIPYAQSTFGENRFKLAQPLPASAANRIVHAENFGPNCPQYEATAPSVYTKVRREYFIQGVNGDDCLSVSVWAPLYPTEEKVPVIVWVYGGGQTTGGSSVPYQNPQRWVQRTQSHIVVSLQYRLNFFGQPNAPTQNAGLYIFDARAALEWIRDNIRAFGGDSERMVIWGQSAGATLVGALSIGWPDDPIVKGFIQDSGGIEGQGVHTMYQDTAFSNFTFIANQLGCTGNASAKVDCMSTVPQSDVEAFLQYYQDTGLKPAIVFQSYNDNNHTFANYTVAYDSGHYAKLPKILGHNAVDGASTAALQSGPPDIVGPTPEAELAATLHVRCDVVWEAQIRESLGATTYRFEYAGNFSNVSPLPFMGAYHSSELPMIFGTYADIGGEGTQFQKDTSEAMQDLWLTFARDPENGLANAGWPKYSTGVVEVLGGEVNGTQKTRYTVAKGTIEDACLTYTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ09</accession>
    <name>A0ABR3YJ09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000104">
        <property type="protein sequence ID" value="KAL1887940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045202057" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="25332" checksum="1A555BFE07DBC9A4" modified="2025-10-08" version="1">MRSSALLSLLPALAAASPTFVLGDGSTTLNADTAGGAPPAVNLVNPAGSDGTADAPNPNDIQVASVSFSGNGCPQGSVSTSISTDRTVVTFGFDKFQTYIGPGYDLGDKSKNCQLHLNLKYPGGFQFAVLDSTYHGFAQLDQGVTGTFYSTYYFSQDAAATTTTQTSISGGGTWAAGQVYTKNDQIPTASVIYAPCGANGILNVNNRIVLASNNKTATGQVTDDDATVAFTHQLHLTWRPCPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ16</accession>
    <name>A0ABR3YJ16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">beta-glucosidase</fullName>
            <ecNumber evidence="16">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Sste5346_009954</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="16"/>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF20">
        <property type="entry name" value="BETA-GLUCOSIDASE E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 16" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="19">
        <location>
            <begin position="913"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="531"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1887842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="998" mass="107640" checksum="E3D7CE4E8F3A24B1" modified="2025-10-08" version="1">MVTDDQAKRGLLSSGHGHNRDARNSYELGDSDRESDIDATEFLTADPLYEDDTSDDKKGNRKIQRGARHAIRWIGPACLPKRWSRSRCCIVALLIGGTIFLLTAASGGFVYKKLGEEPPYGQSPPWYPTPPGGTAKKWADSYAKAAKMVSRMTLPEKVNITTGTGWQMGLSVGTNGPAVHVGFPQLQLQDGPLGIRMADNITALPAGITVGATWNRALMYAHGKAHALEARAKGVHALLGPCVGPLGRMPAGGRNWEGFGSDPYLQGIAGAETIRGIQDQGIMATIKHFVGNEQEHFRQPYEWGLPHALSSNIDDRTLHELYAWPFGDAVKAGVASVMCSYNMVNNSYSCGNSKLLNGILKDELGFQGFVMSDWLAQRSGVSTALAGLDMTMPGDGLRWQNGLSLWGSELTRSVLNGSVPLERLNDMATRIVAAWYQLGQDDPNFFSGFDGAGERPNFSSWTYNKTGVLAPGSPSPQETVVVNQFINVQGDHANVARHIATEGIVLLKNTNNTLPIGTDGVTGQPNRIVKAQHPAPQSSSQPSKRDANIAPTPKIKIGIFGEDAGPGQGPNFCENRACNQGTLGSGWGSGAVEFPYLVAPADALSAVFDEKKVDIRRRLSNRGVQPESLADLDVCFVFANADAGEGFVSWGGNGGDRNDLLLQKGGEDLVYSVATGCGGGKGDVIVVIHSVGAVVMERWIDLPQVKAVVYANLPGQESGNALADVLFGRVNPSGKLPYTIGRTMDDFGPGGKVMYIPNGVVPQQYFTEGLYIDYRHFDKYNVEPRYEFGFGLSYTDFVVGNLSVKGVLPKSALPAARSPPAAKAPTYDTTVPDAKEALFPKEIRRLAKYIYPYLDSVDDLDIVSEKYPYPDGYDTVQPPSAAGGDEGGNPDLWETYVSVSVDVANVGSRDGKAVVQLYLSYPDGAADAAGVDFPVKVLRGFEKPLLKKGQTQTVTFNLTRRDLSYWDVQRQNWVMVTGGAYRLLAGQSSRDLPVQGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ48</accession>
    <name>A0ABR3YJ48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosome-releasing factor 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MEF2</name>
        <name evidence="6" type="ORF">Sste5346_009620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000094">
        <property type="protein sequence ID" value="KAL1888340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="2"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="842" mass="91367" checksum="880A078A8D733776" modified="2025-10-08" version="1">MADIRNIGIIAHVDAGKTTTTERMLYYSGVSRHLGNVDHGDTITDFLPMERARGITIQSAAISFNWPPEQHLTQGQTPKTINLIDTPGHQDFRFEVDRCLPVLDGAVCIIDAVKGVEAHTERVWASAQQHSIPRLVFVNKLDRDGASFQRSVLDVASRLNAWPLVCQIPLWDKRGDEFQGVVDVIEKRGMRWSSNGSLSLVPEQTLRATEGLWEEIETARVKLIERLCEDDDELVEAFSEKGTDLPSSLVKASIRRVVRTANGGVVPVFAGSSLRNIGVEPLLDAVVDYLPNPQETHDVEVRIGKETHMLGEVLSGDFVEKSKGGKGGKKGHKGHHKAAPAHSGNSTKAGALASVFKVVNDPNLFPGTHGMLTFVRVYHGSLHKNTQVWNANLAKFEKPFQIAQVSAAKIGEIPYLAPGQIGAVTGLKSARTGDTLHILPNSSQGGLSISTLRTMTIRPPDVGPAVAFVSVEAYGPTETKKLADALDKISREDPSLRWSRGDEAGTEDTFVLSGMGQLHLDVAIDRLRTTYQVSASFSDVQVDYKECLTTATTGAKRYVYDRVVANKSGMAACTVEVERIEEGEVMETVEAAGEEHNAEKPGEATFHFERDGNFFFIRFEGGAGEEGGEHADLPFDADMVSRQLFSGAYGAMSRGPRRGSPLHSCKVTVVFNAETDYGGPGTDGHIVNAALHGVRNALRGAHSKGQVGVLEPVMSVHIACPDDSAGAIQRDITGSRGGFVLEVRESSSEGGSTDGKSSFLSEGEDPIDLSQVYAPPDPYISIQSLREAKRGVTRLLEIVAKVPLKEMLAYDQRLRSMTGGRHSFTMELGSFERVVGSREKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ93</accession>
    <name>A0ABR3YJ93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fcp1</name>
        <name evidence="10" type="ORF">Sste5346_009593</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000093">
        <property type="protein sequence ID" value="KAL1888385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="165"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="547"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="338"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="468"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="645"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="379"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="667"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="711"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="841"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="869"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="884"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="897"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="935" mass="101252" checksum="EBACA48F1F55851E" modified="2025-10-08" version="1">METGKKGEKTLHFGARLKYPIRITKLYKTPGDTIRRQEPVLQYSYEYTMELPQDRETLELQKKTLTSITDWNAPEDGKLLAWKVRVGDVVARDRACVTVEEACTHEIQFQGLCALCGKDMNEVNWASEQRDTDRAPINMTHDQTNLTVSHTAATRAELELQQRLLQQRKLSLVVDLDQTIIHACIDPTIGEWQQDASNPNYEALRDVQRFQLEEGHAGGVARGCFYYIKMRPGLREFLAAIAELYELHVYTMGTRTYATNIAKIVDPEQRLFGNRVISRDENGNIVAKSLQRLFPVSTNMAVIMDDRADVWPHNRHNLIKVSPYDFFKGTGDINSSFLPKRDDLPASSTPAAAAAASSTSAPASTSSTPTVAKDDKEVTASPASTAASTAVSGGSDSASDSASTAAASTPATSVANGGTPPANGSSSPASGDENTIDVVLLQKQTEEQERAIEKQIKDRPLLHMQEQLDKEDSEKAATTEATEDNSQATQTRHSAVLFDDDTELDFLKEHLTKLHHEFYEKYDEERGASTELIVDGIPDVGEILDKLKGEVLEGSTIVLSGLVPLGLDVERSEIGMQAKSFGARLQRQISRKVTHLVISSDRPRTQKVRQAARIPTTKIVNQNWLIDCFSQWAHVDETPYLVEIHPADRGQPGGGAGGAVGGTDTDTVSDADADPDDSDNDAGSATNGNPGLRINVPGRRRRAAGDGNTDTGDEGDDDDEFDEFNNSDGMSPIAELGKFDWGSADDELEMFLAEGDDEDDEDGDDDERDESEYGGDHDDGDNDVDMDRNENGDADANGSLLSTSSKRKHNGGGGNDTDTDSERATLRGRSLLAKRQKLASRSRSASQRRAAVALAASQGSGSGSGSGSESTHPLRQQTNISKEPAPTSAPAVASTSNDDDIDDDELEAMLMAELDKEEEEEAAGAGAVGAGSDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJS2</accession>
    <name>A0ABR3YJS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metalloendopeptidase</fullName>
            <ecNumber evidence="11">3.4.24.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRD1</name>
        <name evidence="11" type="ORF">Sste5346_009506</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.37" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="993" mass="111000" checksum="89EB5919E01A9C24" modified="2025-10-08" version="1">MSSNQFDAQASTNYKEAFSLFDKRGNGRVALDSLGDLLRACGQNPTLSEVRDLEKNVGGDFDFETFQRILNRPGGFRDPGEPEEYCRGFQVFDKDMTGYIGVGQLKYILTNLGEKMTDEEVDELLKAVDTSSGQVNYTGPNESTFTLASYTPVPSSPHSPDRSPSASPRPQSPRLRSPSPSKRSSRRFHLVAALVVLALFVIYVATLATRVLPRLSFAVFRGSTQPQIPFLTQLKDQQQNYHPISSQQVYSFSTSHPTYATYKPIFTNPSVESMADKYKNPPQAPPTFKGTKESILADAKAICDRTRAILDKVVADVPPVSDASKTTFDTVLGPQIEDENDVSLTAHILGFYQYVSADSDLRDASTEATRLMDEFGIECNMREDVFKVVDATVQTYGGKDALEATGGTVGGAVTPLNPESARLLVREHKGYIKNGLGLPAGPQRDRFKEIKKRLSQIQIDFQKNLNEENGGIWFTREELDGVPADLLDGLDKGEEGSENAGKVRLSFKYPDLFPALKFAKNPVTRRRIFVDNENKCNANVDLFHEAVLLRDEAARMLGYPNHAALRLEDKMAKDVKTVDDFLGDLRTKLAAGGVKEIDHLLALKKSDTTELGLPFDGNYYLWDHRYYDRLMIEKEFSIDENEIAEYFPLRTTVAGMLKIFEELFGFVFVELGPEERARISPTGRAEDIVWHEDVIVFSVWDDKSEGEGFVGYLYLDLHPRQGKYGHAANFNMQPGYKQSNGTRRYPATALVCNFSKPTPTKPSLLKHDEVVTLFHELGHGIHDLAGRTQFSRFHGTSTVRDFVEAPSQMLENWCWSPPQIKALSSHYESGKPIPDSLVEKLVATKHVNDALFNLRQLHFGIFDMTVHAPESHATLEAMDISSVYNDQRAQISGIKGPEAEGQPSTWGNGQACFGHLIGGYDAGYYGYLYSQVYSTDMFYTVFKANPMNGTEGRRYRHTVLERGGSQDEMKTLEQFLGRKPNGEAFYRDLGITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK03</accession>
    <name>A0ABR3YK03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="758"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="814" mass="86717" checksum="A1C59E7EEFDD2611" modified="2025-10-08" version="1">MGRPPAYIFIVRHGNRLDAADKLWHLSSPTPYDPPLTYGGWSQSRALGQRIADILRESTPPEHASSSDDLNGKQPPKKRKYKIVIHSSPFLRCIQTSIAISSGIASDSLPLEHPRTFEPLPPLRVRTPASNGPTSNPTSNPGYFDAAPKNIAPRLNKSVMRLDAFLGEWLSPGYFELITPPPSSVLMVASAKAELLRREDYSSFSHTTHHQATHAHSHSTSHLWGASRSNTWSSRPTDEEDLPKSGSQPIPPMTPTGLFGNSGADGRPMSSNGSLQTPKWDSSSGMHRPSLAGYVAPVPQFAMSSRAPTPTGYVAHARDACVDLDYQWDSMRAPYDWGDGGEFGEEWTAMHRRFRKGLQKMIDWYTTSDAPAEMVTKTVQFKTGHSKTNSRGSTIDDEECAIDDDDGDSDVVDDDCIEETVVVLVSHGAGCNALIGAITQQPVLMDVGLASLSVAVRRHGMDSLTCLSDDEDSHKDSSKWSGAVHSGHPGGVVPLSKYFEMKLLANSDHLRSVPTTPTTPRGGGSMASVMGGTRGRHSNSLSGTPGNFNLFESGVVGQRSSSAGSFHGGADISTRRPSGASSRPPLLSKNTGGSGAGSSSSNGRGPNGITIGSGVLTFSPPSISTSRLGHSRPGSIGLWSPVSSKDPDEDNFALTDDGDSKDDDDMEILLSFGPESPKSPPQPEEKKKKAPSIRGTSNPIYPSSLSIAHSADGDHDDHSESTGDILKGDYSAMTSALPPLDTRGPTSAPSSTYGAERASTNTSTPSTTSTTARSASPASPGLWINPRVVSISSDELPHENAGSKRRWTVTEPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK35</accession>
    <name>A0ABR3YK35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">beta-glucosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_009386</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWCUI010000087">
        <property type="protein sequence ID" value="KAL1888681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF3">
        <property type="entry name" value="BETA-GLUCOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="12">
        <location>
            <begin position="453"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="892" mass="97774" checksum="507A150B0283D8E3" modified="2025-10-08" version="1">MPAMQPVVSGEIDSDSGIDATTSPLGSAGPSITPDTEISPPNSPFTPSEKLNDARQTAKKKLATLTLEEKVSLLTAADFWRTKAIPEKGIPAAKTTDGPNGARGSIFVGGTKAALFPCGISLAATWNKDILYSIGQHLGNETKARSANILLGPTVCLHRHPLGGRNFESFSEDPFLTGKLSAQYIRGLQQKGVAAAIKHFVANEQETERNNMNTVVSERSLRELYLRPFEIAVREASPWAVMSSYNLINGVHADMNHYTITEILRGEWGFDGTVISDWDGINSTVETLKAGCDIEFPFSKKWRFEKALKAVEDGSLTVEDIDRATENALTLITRVKGDDVSEEAAEREDNRAETRELIREAGVQGLTLLKNETSILPIDPRTTKLAIIGPNANRAIAGGGGSASLNPYYTTIPLESIKSALKEAGNQDEVTYAVGCHTNKWLPVASPLCTTRDGTQGVTIDWFAGDKFEGSPVLTQTRYNTDLFLWDSAPVAQVGPQWSAIATTYLTPTSTGKHTLSFMSVGAGKLYVDGKEVMDLWNWTEEGEAMFDGSIDYLIDVEMEAGKAVELKVRMTNELRPISKQKKTGATHKYGGCRIGFKEEDQIDYIQEAVETAKAADVAVLIVGVDAEWESEGYDRQSMDLPTDGVQDRLIEAVLAANPNTVVVNQSGSPVTMPWADKVPTILQAWFQGQEAGNALADVLFGKKNPSGKLPCTFPRRLEDSPAYHNWPGENLEVMYGEGLFIGYRHYERAKIEPLFPFGHGLSYTSFEYGRPSVNTKTLSSEVGSTVDITLAISNIGEVEGAETVQLYVHDEKSRLIRPEKELVAFEKVFLEPGETRHITISLDKRAVGYFDTAINRWIAEEGRFNVLIGASSADIRRTISFDVKKSFNWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKN5</accession>
    <name>A0ABR3YKN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial import inner membrane translocase subunit tim23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIM23</name>
        <name evidence="6" type="ORF">Sste5346_009364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000086">
        <property type="protein sequence ID" value="KAL1888738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="245" mass="25423" checksum="5DB1CF5235BFEBC8" modified="2025-10-08" version="1">MSIWGALTGRKSSEPAHNDSPSASPSSSSSSTSAHTTVYDSSSPAGGNAALATLGGEGANSFLQSSSFADPTQLHPLAGLNKETLEYISMEDSALSDLPGSQSVLPSRGFTDDLCYGTGITYLTALTLGGAWGLQEGLRRSAGQPPKLRLNSVLNAVTRRGPFLGNSAGVVAICYNCINSYIGYVRGRHDAMNSVLAGGLSGMLFKSTRGVRPMLISGGIVASVAAAWTITRRTFFPIPEPHSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKT5</accession>
    <name>A0ABR3YKT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_009565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000092">
        <property type="protein sequence ID" value="KAL1888448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="342" mass="38590" checksum="E6FB4223D5A8FB65" modified="2025-10-08" version="1">MTAILGSVTDHYQIIMAPPPPGVVSTDNLGPYYPKALGLDQEWVSCRQIMPEDFWQEDNTSPAIRDLRLVDLYIRQTTKIRYFIIGRHIHLAYALKANKDRRYSYSRTACLEASREIIAAYQTMRSRGHAEWSPCGMLDFESFSAAMVIALAMLQDSASSSTQQRQRTRQEEEDYALLVELSLSLRKTHLLKGSCTVAQRAADVMDIVLPILQGQYRRSAKEASSPGTSAADHDINIPFFGRLRVTFPRLETDQSPSEAHSSPSMPETLTSNEIDMSYSAQTAQMSLNDVPITPPIIEFGVPFCNQDFHYNFDFDMELNADWMNTSDMGIYDWTTMMAPGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMG9</accession>
    <name>A0ABR3YMG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable kinetochore protein NUF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">NUF2</name>
        <name evidence="18" type="ORF">Sste5346_008989</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NUF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.60">
        <property type="entry name" value="Ncd80 complex, Nuf2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005549">
        <property type="entry name" value="Kinetochore_Nuf2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041112">
        <property type="entry name" value="Nuf2_DHR10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038275">
        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18595">
        <property type="entry name" value="Nuf2_DHR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="16">
        <location>
            <begin position="27"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Nuf2 DHR10-like" evidence="17">
        <location>
            <begin position="279"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="173"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="327"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1889334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="461" mass="53167" checksum="5259E011B710492C" modified="2025-10-08" version="1">MTFNPRMSILPPNQHRNARPKDVPDLLVRLTDKEIVACVADMGIPFSVADLQKPNPLLVQKIFEWFAEELLNVSRETVEPAMRAAAEEVCGGEYGDVLMPADTRCLMGFCASLRVLLAECCVRDFSLNDLYRPTYERLVMILSYLINFVRFREGQGHIVDQHAQRGAMTRQRADELYGANQDLERRLEALRAARNAAEAEVREKMQRNDALKRSLVDLQRSQRQVGARLDEARERKRQLVDQLERRTQSKIVLRQEIAKLQPYVLQSPAALQASLADLSNTLANNRAHIESLERRARALQTSADSFNVVAGDVAACIKLLDEIGGELSKEEEDNAKKTRQRDALTERGADVKEVERAELMLQKQLAKWNERTEKLREQSAQKAQEAKEKMEELKQIHRTLNEERSDKGRDIEKRRVRIEQTEKKMLDLKENIENEVHNAYDEYLKMESHIKLYITEMEQTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMZ1</accession>
    <name>A0ABR3YMZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="117" mass="12588" checksum="43C559EE1D67B5E0" modified="2025-10-08" version="1">MGHTEESHVNAIDVETEVSLAGKIIAVTGANRGIGLGIAECALDNGAAKVYSIDVRSPGTDSDDEFVVMPNKYLGRLFSVVAEVTKQASITAAIDRIVNAAGAIHGHRRRWFERVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN10</accession>
    <name>A0ABR3YN10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="357" mass="39952" checksum="3131503DB173760E" modified="2025-10-08" version="1">MLRSAFRAVTRGATLAVPRTSFSSQIARTITTRATQFPLNTGGRIPALGFGTFQDADAQEDAVSQCLKAGFRLIDTAQVYNVEKEVGRGLKKSGVPREEVFLATKLWCNTFHPDDVPAALDASLEALDTPYVDLLLMHYPVVFQRGEERFPRDASGKMLLGKTTFVDTWKAMEKLLESGKVKALGVSNFSQGEIQKLLDECSVPPAVHQMEVHPYLQQQAFNGWLKEKKIHVIQFSPLGNMNPFYRQTGWSKDIAHTTPPITESPLLLEIGKKYNKTPVQIALAWGINNGRSVIPKSVVDWQIEQNLEADFELEAADIERISVMDQKARFNDPSADYQYRLYSDLEGIEGTKEGFTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN80</accession>
    <name>A0ABR3YN80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Galactose oxidase/kelch, beta-propeller</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_008967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247697" description="Galactose oxidase/kelch, beta-propeller" evidence="3">
        <location>
            <begin position="21"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="708"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1379"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1454"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="782"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="801"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="887"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1201"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1235"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1379"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1399"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1414"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1462"/>
            <end position="1475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1529" mass="158591" checksum="F590B92336B9B659" modified="2025-10-08" version="1">MAPQVVLLAALLQLLPRVAAASSSSSTPAVFPYTPTTILVPSADSSVVYLFSASESGQVEFLSLNISSTLSSSSTDGLKFLTTGVPFLANSSQENTATTFTPTVRSDGSIFVYAGDCSSSSSSSAAVWSYDPSSSSAQWTSSTLSLSSSQSGPWFLGGSTAFSNQIAPTMSNSTFYIYGGMCPTTESDSSTATSAAATATSITASNWQGSASYSNKMLKLVPSSNTYTPSIVSSKGPPIAEAGFTFTALSASQSNRSGIVTQQVNSVVLGGHTETAFVNMSTAAIWSLPEEAWSFVSIANPSSSSSGNTELAVLRKDSSSVSTAAPDSRSGHSAVLSEDGNSLIILGGWVGDVNQAADPQLAILEMGPDYGQWQWSIPATQPSGTGMYGHGAALLPGNVMVVYGGYNISSSTSSAKLIRRESTNGGNGLMFYNVTSKSWSEDYTNPTYDSSAAAPSSPKSSSSTSKIGLGVGLGLGIPLAILIVVLLVRSCRHKGRQRRRRDEAVRALAQDHQQFLHGHDEMVENSPGAGLPFGWGNGRESMGFYTGGHDPYNSGRRSLGFETLRGAKSSPAFPSYQSPNLNGDEPSMPGPTFTSARKPARNVARGLYQPTNINDYESFLALGNNGGAAAGNGTNGIHPIYEADEEDDDNGTEKGKQRGDMGSRSISPETEELTDPFLTPSTQSVNAGSANPMRSSYAGAFGPNTVNLNPFVRNTPSPEAGTGPSRAPHGGVMGGADLGVMDPSGAPTGPLRVGQDRDVQEWVSGLEIEDLLFSPPAPGAGAAIAASVSPAPGAQQRGRVSPTNTNRRLSLRSKASTGGSPTRSTFLGSAAAAAAGAVAGVAGAWGGGDDEARTGSNLSDKSAFSFLSRTTSSRGHGPHSGAPNVLNNKASNSDSSSASFNTAQSGFRSLRNEGPDLLYGKGHQNGSSAGGSFGAGGASNNSSGHGGASTPNAYTLNAPPTLPPLGFGNSHEYGGAAGVMAAGAVAGAAYHNRHASEDDENDALTGSPSKLKGRRTWMGSIMRIFSSGSPANANLDTDASLDAANSSSMGTGAQQGPNYRDMAHATLLRRKQGRSDWEADELREEENTAVGALRSGGRTASIGSMHGYSHSIGQGARSGAGEQSASGNIAVGRRDGSGKSDEWDVEKAVQNRVVQIMFTMPRGEQLRVVNAEVEREDDEADIGNLSQSVDPHDYSINTDLDHDDTVDDDDAGGLSAPPPPPVLQRPYHSYRSRSPPVTTDTTKTLANDQYRALPPPPKLASPTPPSIIDRQDEQLRQLHEALAESKRLLSTQAIEPWMLDAHDDDDYEDDAATFGEEEVHEDEAQAIPINKGKVVDVGWMEAGSMPSPLNMSYVSEKRSQVAEERERLATAAALARVFMSRPGTGSSPAATPPSARRPVPAPAPVPAPAPSIPTMPAKPAAAAAPPASPTRTQAAMPTTPTKALTPVRSLASTYKTPTKAVSTDSLSTNTSLTSRRSGRRGTLGGDTLLGSPAATEAASTIKKPAGFVLNMVDKIELTGSPKSGHSRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNF9</accession>
    <name>A0ABR3YNF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_008621</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000068">
        <property type="protein sequence ID" value="KAL1889896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF20">
        <property type="entry name" value="PRO1A C6 ZINK-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="619"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="788" mass="85357" checksum="3839C15D0BF1D91D" modified="2025-10-08" version="1">MTSRPPRSSAGCWTCRLRRKKCDEARPVCEACAALEIECLYSEARPSWMDNGPRQRAMADLLKLAVKDRAAWRREKRFLRDIETGAAAIRLGEADDDFANGMMNGVGRATHIFSVDTLSSNSNSNSNSNSNSNSNRNSNNNVMMDGPASPPSTASPSDSSGAEHHAPEAATSGPSTATTTPAGIPSRLPSAAWTPEASLAPPNLEQERELNLMMMYLDYVFPFLYPFCRPTVLGSGRGWLLVLLMKNKAVFHSALSLSSYFLAVVTNTTHALNHIPLSKDPMKATAATTTSTPTTVSEAIDKGMESKDRAPGNHSTCLVAMASELHKQQELSLRELQRTISCISVNPPSTIPCADGSESHLAQSARALESILQLLNFEGLLQRFDRWHVHLDAALALFEQVMHQYGSATLEDGSPAPSGGGWPAIMHQLSPFHASLTAQTLSFPVPYGSDQAALKFYASLLLYMDIVTSTVTETAPRLQQYHQALLGSSEGEGDAPGARFSFVLFDPSRSTLLATDEVIGIRNWVLLALADTAALAAWKKEAAAARRLTVSELLARAASIEQRLRANLQHLKQKMRTAKPHLGQPAAEGVLPSGFYSRYIAAAEAQLNEALTERQNECRDQEQDPHNHIHNNRHNDPSLPAAPHADMAAHLSVDTVSHIWGLAVLSYLKVVVNGWQPAADDVRETADALLRELAALPSASCLRVAAWPLCVAGCLAASPQQRAIYPGMVGEICGGELFGTVNEALRIMRAVWAAQDLQALGGGGVGSVHVEWDFARCFNILGRRAYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNJ4</accession>
    <name>A0ABR3YNJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_008905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000074">
        <property type="protein sequence ID" value="KAL1889421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="746" mass="80811" checksum="8F2F6637BECC724F" modified="2025-10-08" version="1">MDSLRIIPEAAWLAVRDVPNGFSNSNNNGSGIFQLGANATQQQIQFISELRFAAAKSIRTSTIILAAFNAVAAFATACGILYDAYSTRKRNNKRYGTAVDRPKVPFIQPAELFPLIISIGIAVQGVGFSVAQAQGLQSLLSIGCTLVSQFMLPAVFIVPYIQLVFGVEFAIRGLRKSPFPARGRYTTTICLIILGMLLLTNFLVADFIRSPDFCFASLFWFVAIYSRGCFAVLLAIDIILVLCTAIIFVRLTRSTKIDIAERISASRMVYYLALGILSNTLIMPFFFSLAFQYEQDDGGQAITLSMVASVVAGVSGLMTGGLHLFLRSTTISTIGPRGKAGEYERYRMKDRIRRYGGSEPDFQGHMMGPVGRGTDLRRMLSDASLISGTVRDRKEEEAGVLVNRNLSPSYEISPRRPNPLRSNAFYPMDMTSDSATAVSIQAPEPVQMSSASVFSSSAMSAASTRKVPFSPATTKSLVLLPATTYMPGSVRIISANNNGRYDMSSLKPPPSINNLTAGRHRRDSSMVSSATVQIGLRLSNVEDFAPMESQIMDKDVYSLYISGADESGTTAAAKEAEQQRMTAAFLAQQQLPLQASQLAPARRPSPLSNLGRLAISDNQEDLVAIEDVSPIRDPIKDARMKTLPPVPRPQDSIVLPSAQTLSQKAYNPDEDIFASGPTLSPSVYSPQQSPTKALLTTKLPSPRGVGFASVSRSNSSAVRSTAPTLRREMSSASHTGVPSKTASDWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNP7</accession>
    <name>A0ABR3YNP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBM-cenC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_008569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000067">
        <property type="protein sequence ID" value="KAL1889990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247696" description="CBM-cenC domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="18066" checksum="634393A58016C7EE" modified="2025-10-08" version="1">MKVSCLLTAPLLWAGMASATVCKPSTPQVCQNILSAPDFSPSSAWIAYFPANQAPADNSWTPTAPCGDYDSCVQITAHQDTALSIQSFTYPYSGAYTASLKYKVLNAGDGSGNLKFGLVTGEAGVTTNAVTSTWETYTIDFTANAGGGSLYLAYTASGFGTIQVTDVQIIACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPC1</accession>
    <name>A0ABR3YPC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_008707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="91"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="754" mass="81747" checksum="82450F02AF3439CA" modified="2025-10-08" version="1">MPSTPVNSAGPGPTTDIAASSAPGMGAPSAYREAVEPRYSRGRKSRGRGLRKTTGCLTCRRRHISCDELKPSTPSTPSHSNRSSADTIKVASASSSTAGPTTSTATSTNASACTSSNSSISGRRDGVVAEALPQPPIDEDDGMTDAPPVYDTAQSEAHDRRPDVDSRPAVTALSPPSTSAPGLSILSAIATATPQQPPQQNTSAPQNTTSTSAPLHQNTPHSIGTPSTTYSLQLSPSQVRSNPHHAPSVSSGRVSVSQDLFGGASAGSVFSIVPNINIESATAQWLGLLIGDATQDAGGGLPAFEWDCEEAGGLDVFGNSVAAPDITVPEDVPSVSNSTGNKSNPGLQERFSRLVGEQQQLEMQAWHTAIPIELLPHEYALFQHFVLSISCTMDLFDPKKSFGTFVPHLAMHNVGLINAILALSARHLSLKAKAKGHTGDDNALGLANAPSENEAIRYYYKTLHYIQKAMEYDTYKTSLELLATSIIVSTYEMLDGSRRDWERHLQGVFLIQRSQVIHGDSGGLRAAVWWSWLCQDVWAAFRERRKPLTFWQPTRRLDELDPYELAARSVFYFAHVVAFCSSEEMEKHRASPAARMAKADALLESLADWRLHHTVEFEQLPTLSTPEESEAPFTPIWIHPPAFGVAVQLYYCSLILITLNRPLVGDLDAYLQQRKSIQRYVAVVCGIAMTTTTLTSEDASSVMCSQCLYIAGLSIEDPKRQRAVLELLERCRQRAVWPATPLSDELARKWQESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPI8</accession>
    <name>A0ABR3YPI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Exosome catalytic subunit dis3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DIS3</name>
        <name evidence="14" type="ORF">Sste5346_008456</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000065">
        <property type="protein sequence ID" value="KAL1890163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09862">
        <property type="entry name" value="PIN_Rrp44-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033770">
        <property type="entry name" value="RRP44_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17215">
        <property type="entry name" value="Rrp44_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="12">
        <location>
            <begin position="86"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="RNB" evidence="13">
        <location>
            <begin position="548"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="336"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1030" mass="114545" checksum="D5BAE3C2A064CF56" modified="2025-10-08" version="1">MATLKRPAPVDEGIGPNLSSKTFVRTTKSGKVQKIVREVYLRQDIPCSSQLCVTCQENAPRDAAGHVSPFVLSDRPAGTTAYPQGHYLVPDTNAFLTAMDLFEQTSAFYDVIVLQVVLEEVRNRSLPLYNRLIGLTRSDEKRFYVFFNEFRLETYVTRESGETINDRNDRAVRRAVKWYTEHLATAAAHVGKPTPAVVMLSNDRDNLRKARSDGLAASSLADYVRGLENADVLLDMIPETQDPSVTASREEKKAGANGHHLYPEYMTMSKMMTGVKSGLLHQGNFNVSPYNYLEGSVRVPAFPKALLILGRENINRAVDGDTVVVEVLPRDQWKQPSTKIIDEETVTKNESADGGEGEDDAAGGSRGGDLVSAKERKALQEEVKRTQALAGQRATGKDGKNEPSTYVEPTARVVGIIRRNWRQYVGHIDQTSASKATGQGRKQESVFVIPMDKKIPKIRLRTRQASELLGKRILVAMDAWDRDSRHPVGHFIRSLGELETKAAETEALLLEYDVQYRPFPKTVLDCLPAEGHDWRVPTSKEDPGWVDREDLRDLLICSIDPIGCQDIDDALHARPLPNGNFEVGVHIADVSHFVRPNNAMDLEASVRGTTVYLVDKRIDMLPMLLGTDLCSLKPYVERFAFSVIWEITSDADVVDVRFTKSVIRSREAFSYEQAQLRIDDVSEQDDLTKGMRTLLALSKKLKQKRLDAGALSLSSPEVKVQMESETSDPIDVQTKALLDTNSLVEEFMLLANIAVATKIYDSFPQTALLRRHASPPKTNFDELSRQLRAAGPVSSDEGFVLSVESSKALAESLNACVDPNEPFFNTLIRILATRCMTAAEYFTAGSLAYPEFRHYGLASPIYTHFTSPIRRYADLVVHRQLAAAIGYSSSATATRGRLTAVCRNINMRHRNAQLAGRASIAYYVGQAVRGKETVAEGFVMRVFSNGFVVLVPRFGIESPIRLRDLATPEPAATFDADKYVLETSRAVPTGKGDETKLEPVTIRLFQKVNVRITDHKDETTGKRSARMELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQB1</accession>
    <name>A0ABR3YQB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor sap61</fullName>
            <ecNumber evidence="9">6.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sap61</name>
        <name evidence="9" type="ORF">Sste5346_008502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031774">
        <property type="entry name" value="SF3A3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024598">
        <property type="entry name" value="SF3a60/Prp9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF2">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16837">
        <property type="entry name" value="SF3A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11931">
        <property type="entry name" value="SF3a60_Prp9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="8">
        <location>
            <begin position="429"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="524" mass="59959" checksum="C80F349E4D2D8CA7" modified="2025-10-08" version="1">MILEEIRYILEDLERLEQAVVDRLVDEPTQVRDRLNREHEVAQLLDHMQAQSGEALRLYGDANDMRRDEVTLSGEGDPLSLFYKHCNETLAYHQRYPSDQIDQPELRYRHKPQQLMSEYGEFQPTLVDTMFSGEEGFGRFFDLNANYEAFVNLPHVKRATYLQYLEVFDQFGDSNPYTTSLKRSDKLTEDYFQYVGGLADYLEGFMRKTRPLENLDRVFSGFDDDFDALWENDELANWKAEAGGATEGESGGDGDTPVLSSPEAVWCADCEKEFKNQNVYKGHLSGRKHVRAAEARAQSGASNGGGGAPAAAAANRLKERAVAAREYRVQRLVAAMSTEKDDTRVNVERRQGMTERERRQELDNLYAMLQESAQPMDVDPHGEGEGEDGESEGGDDDDKVYNPLKLPLAWDGKPIPFWLYRLHGLGVEFDCEICGSYTYMGRRAFEKHFNESRHIHGLRCLGINNPGLFRDITKIEEALRLWDKLEKEKKRNKQDETGVVQMEDAEGHVMPEKVYYDLQKQGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR27</accession>
    <name>A0ABR3YR27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000063">
        <property type="protein sequence ID" value="KAL1890308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="281" mass="30459" checksum="A8806574AF3EB570" modified="2025-10-08" version="1">MMRVREPCNIDDSQLLEGNVGEPIRGLPLDVPTDMSYYMQRMRLSKVARGIVDRMPMVSGTQFVGGPASSSASAASLLAAYRESAIASDAELDAMLKDMPLFLRFETYEQTQIEWTEDDEDGKSPKTTIVLLIDLCADNGTGSEMDTGDDSPDTSAAFAALQIVSDARPYSPAAAELYTSLTQLLANHRPQLLEEGLQRLGTSMPEISSATTDTAQSVIPATSATITSPLNNATQDYSLSNLAFNDAMYTNPMALHFDGLDDLAQFQWDDLLAGVDTTMFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR79</accession>
    <name>A0ABR3YR79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_007997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="7770" checksum="F4076920623CCCD7" modified="2025-10-08" version="1">MSSLDKDRLQQEMSSLPLSSISTSIAASSTSTAAAASSSNTISYSLSPASTSNPAFLGMVITGAVNEVLSSTTNYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRJ2</accession>
    <name>A0ABR3YRJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PRP43</name>
        <name evidence="13" type="ORF">Sste5346_008131</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000060">
        <property type="protein sequence ID" value="KAL1890615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17973">
        <property type="entry name" value="DEXHc_DHX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044756">
        <property type="entry name" value="DHX15_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="166"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="356"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="822" mass="92834" checksum="02B8BAAB42A6E2BD" modified="2025-10-08" version="1">MPCLDNSNPSSSSSLSQSKKRPSALDPDFGTDSNNNSADGLPPMKRNKGESGERSEKSKTPKVESDSDTASAKKSKLAKNPYLAHLEDDENNSNNESNSKGKQPLYTTEDSGFAGMVRHQTTAEQVSRVEHEEYNAFTNRAHTQQYFRILETRKGLPVHKQRQEFLDMYHSTQILVFVGETGSGKTTQIPQYILYDEMPQLNRKMIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENCTGPKTLLKYMTDGQLLRESMNDPDLSRYSCIMIDEAHERTLATDILMALLKGLALRRSDLKIIIMSATLDAQKFQRYFHNAPLLAVPGRTHPVEIFYTPEPEKDYVEAAVRTVLQIHATEAEGDILLFLTGEDEIEDACRRINLETDEMIRESDAGPMTVYPLYGTLPPHQQQKIFDKAPDPFKKGGRPGRKCIVSTNIAETSLTIDGIVYVVDPGFSKQKIYNPRIRVESLLVTPISRASAKQRAGRAGRTRPGKCFRLYTEKAFKQDLIEQTYPEVLRSNLSNTILELKKLGVEDLVHFDFMDPPPPETMMRALEELNYLACLDDDGNLTQLGNMASDFPLDPSLAVMLITSPEFYCSNEILSIVSLLSVPQLFMRPASSRKRADDAKAQFTHADSDHLTLLNAYHAFKGEELKGTTDMRKWCHEFFLSYRHLTSADNVRTQLKSYMESHGVELISTPWGDKNYYTNIRRALVGGFFMQVAHRQATGKIYRTIKDNQAVIIHPSTGVGTDFDWVVYNEFVLTSKQYIRTVTGIKPEWLLDIAPNYYDLSAFEEGEAKMALKRVADKIKRREAVRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRS1</accession>
    <name>A0ABR3YRS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NDC80</name>
        <name evidence="15" type="ORF">Sste5346_008221</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000061">
        <property type="protein sequence ID" value="KAL1890550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057091">
        <property type="entry name" value="NDC80_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24487">
        <property type="entry name" value="NDC80_loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="13">
        <location>
            <begin position="155"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein NDC80 loop region" evidence="14">
        <location>
            <begin position="481"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="425"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="629"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF24487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1890550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="765" mass="85922" checksum="208904521FFF5387" modified="2025-10-08" version="1">MAQDTGHWSVRRQRETLGGLNLNSTAIPQPPSALKRSNSSAGAANNAGPVPFSTSGHMRSLSGSRHSLAPTRPSQPLFQRTSSSGNNQTTLADMGLASVKRSSVRQPFSTPGMAGRASTDGGSDRRSSVYRGGRQSTVGAMGGALGGGITSMGGGGGSHQSFFSQAPAPAGALRDPRPLKDRSYLARIGQEVIEYMTQHNFELEMSHTLSQNVIKSPTQKDFVYMFQWLYRRIDPSYRFQKSIDQEVPLLMKQIRYPYEKGITKSQIAAVGGQNWGTFLGMLHWMMELAIMLERYSSNRYDDACAEAGIDVVADHITFEFLAHAYQDWLVMDVDGEDGQGSDDAEQLAKMLAPHIDNMTRQLDQAYAKHEEELAILEAEHAKLLQDISDLEKSTPDLAALDEDFKVMEEDKIKFEEYNDLALQRCERHETRIPLFQEELDRLMAEVSEAENEQRNLRQAVDDQGISMADIDRMNSERDRLQKGIEAAGQRLEDAKRKVAEREVDASRKLEELERTVDRYNTLAYQIALIPDTAANAKGRDYELRVRVNEGPSFGESSSNDAAAATTNMGTGNMENERLLADPMTGYLPGHILNLDLRGHVKNSFLALRKEVSERRSTALETMMKDHDLLDSIKEAMEDKRSEVEALEHRVRAAEQEHEKTKEVTTAQRLASDAQIEKMEKELAKMRASLSESVQLMEQREMNTNIEYEQLTLRASALREELHTEIMRMLNDVIKFKMHVQKNLEEYEEFVTEELVKELGDGEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSZ1</accession>
    <name>A0ABR3YSZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000057">
        <property type="protein sequence ID" value="KAL1890970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056023">
        <property type="entry name" value="DUF7603"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24554">
        <property type="entry name" value="DUF7603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7603" evidence="3">
        <location>
            <begin position="1334"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="556"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="840"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1256"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1476"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="932"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1297"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1563"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="517"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="561"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="614"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="767"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="847"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1118"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1256"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1486"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1534"/>
            <end position="1545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1647" mass="178074" checksum="C37E3A9D6048A3BB" modified="2025-10-08" version="1">MSLDMSSGRRTDLLFPVRNNSPFPSTSSPSSSPSISPTPFSTSESASSLVSTSTDLSSVYPASSLYSAAALSPSSSSNSIGDTDAYASSFSPSAVDINSSAITDSSSLFSSPPPLPPLREFDLSRRSSGRPLPLSLKTTTDASESKRFSPRTSSLSTLPNIATITTTVSGGNGINNISISNERQSHSLTSNSHSQATATAAVTSYSPAASARTSAASVAPVLPIRRKPLASSSSANSVTSNSINTNANSASLSAIVDQASPVQPTESSKLDFDLDNLERDTHSESDQAHDLLDQYDQYSQYDDDEQNEQDSDHQHQSSHADAQYAFDLEDALDIDIGDFLPRPDQRFTRSGSVDSPTLYEFPKTPALFAGAASASASAAPAALAPSSLSKSSLHSPSSSLSSSSEKTVEEAVAENVEHEEVVEDNIVEHEIVEHDAEDEIISDSESDKESVKEDDKESFTVALDSQRTEFRESQQSVEIQEIEDIEALDDTENTEDAQSDSESASSAGTVPSRNSVATTPAAPQTGPTTVSSQHEQDLTTTITTVTLGSTDQILTEQPLYESENSENSNNSGESTEEAPEEPETSHNITQRNSTMSLFTRKTSPPHLSLGSISNTNPNNNHHTTPNDNKEDNAQRSVLPDVHNDKNNNRNSLYSVYDDEELQDKNIPIALPTISTSIVNVNNTNTNNSNNSPKNGSSETITTIVTANIANDADSPSTLKPSNKSPSSAFKLGNFFGWPSASPSTTEFSDQSYSPLPSPSSLQPPPSTTFTHASTLSTPGTNSPSQQQDGFANYGSTHTNSNKNRNLLGIISPAKTQTNANTTGDESSAYYEDYLQTPPIITPGARTAASPSSPLSPHSLAQQEQQFGQIEEMEDELKAISVELAASIRREMDLEDLVDRLQTEVNNPQPTGSKRTSDYFSDSGAISSKFGDYDAAKEEIAQVQRRAEQEKAQIRLELTDKLTDERSRRRVLDQQIKDLSERASGLDLDVRNNNDATGRVKQLESTCEDLRRRLSEERGVKENFEDLLAAMKTELQNASNERDNLRDEVVPQLRARVEGLESQATEHARQIYETTKMQQELQSLKDENSGLRSAAAYSAEASAPPSAGLSRSNTVKGMSAPPSNSANTSNSTTESREALAERLKDVEAQRDALHSALKSLLERQEFQNRENDKKIRVLELERQRLLTASPKKAGYERDVAGLRDEVSVLRRRAEEALEQKWQVEKGLSGLKMDLDRAEDEIAHLRTLLQQHDILLPSSDSSRSASNTSSVYDTDGTAATSLGSLRSARVTSASLETAYKFLQKSYADALDRIRALESSSGAPGSVIPSDEKTTLALQRLERSLSSTMAERDAARDEVATHLTRLADSAGSEKTMLENERSLAEQLDASARRVEELAQQVRTQLETNSKLRDRLTQMVARGEADQQTHKNRITGLESRLRALEEQLVATQTAAEDRVARHEEQVAALKEAHNIQLQRLRDASGGIRASSPNRSPVTSPRMLSSSQFGGLGSLGGTIKSPMSPMFSVNGKLVPPPAGSSSRPSSRGSIMSGGGASNSGTAAAAAAAEEQQAQVATLKARVGELETALSKADSEMQEVVGCMNTAQIEVMQLQEELEIAGRETRRLQRLLETEKVKGFEERFKMLSRTTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTK5</accession>
    <name>A0ABR3YTK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS transporter, FHS family, L-fucose permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_007811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000055">
        <property type="protein sequence ID" value="KAL1891178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050375">
        <property type="entry name" value="MFS_TsgA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702">
        <property type="entry name" value="L-FUCOSE-PROTON SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702:SF5">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="43192" checksum="BC3184593AC16637" modified="2025-10-08" version="1">MPFYRRKITVADDTVTSAVNLTTRQSLLPNFLSTLNISSSMSAGLSSTYFGAYFICPPTISGWILRRFGFRVIFMTGLAVLVVGCLLFWPSGVKRSFGGFCGSMVVVGAGLSTLETTADPFLSICGPPRYSEIRLNLAQAIQDVGSFGLKNVQWVYLGVAGFVALLAVLFFLAPMPEITDADINFLESETGKSENGPLRKQYNLFYAVSSQFCYVGAQVAVANYFITFFEEAGRDSTTSSDLLAIGQGLYAFNRFVAGFLLMIPTVKPRYILTLYLGLCVIFIIAAITTTGTASIAILILALCFESACFATIFTLGLRGLGCHTKVGGSLLVTAISGGMAFPAMTGAVIDRRDAHIAMTIPMMGYVLAFAYPVYVNVFKRDLMDSHRSTDVGVIQQNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTV1</accession>
    <name>A0ABR3YTV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fe(2+) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MRS4</name>
        <name evidence="11" type="ORF">Sste5346_007360</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF4">
        <property type="entry name" value="MITOFERRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="78"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="171"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="271" mass="29300" checksum="B1F7E4BC550C8A67" modified="2025-10-08" version="1">MYPIDAIKTRMQILGPSGGTAYTSLIQSTYRMAVGEGIASLWRGMSSVVVGAGPAHAVYFATYEAVKHVMGGNKVGTHHPLAAATSGACATIASDALMNPFDVIKQRMQIEGSGKMYRSMLDCAKYVYRNEGIAAFYVSYPTTLSMTVPFTALQFLAYESISTVMNPTKKYDPVTHCFAGAIAGGVAAGLTTPMDVIKTMLQTRGSAGDAELRSVNSFMAGCRLLHVREGFRGFFKGIRPRVVTTMPSTAICWSAYEASKAYFIRRNDSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTW7</accession>
    <name>A0ABR3YTW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007377</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF15">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="26"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="525" mass="57472" checksum="90E0DF62AE79AE20" modified="2025-10-08" version="1">MAHDWTKVQHERKWSILGMQKRFALWAIYSSIGCMMMGFDFGNAGTITAFPAFQQVMGKPYAGQASGYLISASIQSAWNGVATAGDIAGVMVSGQVLDRIGRKHSILFGVVFTAVGIGMQYASQEWKLYLGGRLVNSIGFGIVYVVAPVWIGETVRPELRGLFLCINNFSIVFGQFILALVAYGAQKVQGRWSYEIVILVQFVFVAVLIVGYPFFPESPYHLLKNNNEERARTMLRRIHGSGDEGLIDAEIIRMKEGIAISQNLEEQAQLNGPLIAQCFQGSNLKRTMISMLAVASQQLIGAAFVLGYITYFLDLIGIDNYFVVSVVLYVIMLLSNLVAFPFIEIFGRRPLLLFGIFGLTAVLLLMGIMGFVHTSGAVWVVLVCIFLWAIIYQLTIGAVGFALAYEVATPQLRPMTASIVGFSQGAAGWVIGFVVPYMINPDAGNLGAKVGLVFAGLGVPLCIAFWFMIPETKGLGFADLDYMFSAKVKPRHFKRVFAERQAAEADSSENGDLKNDAVTAQVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUS5</accession>
    <name>A0ABR3YUS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000051">
        <property type="protein sequence ID" value="KAL1891641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="405" mass="42771" checksum="F73C663C8414BD40" modified="2025-10-08" version="1">MSRPAAPVPVLPPTPEDETNMAQLQPGGGRAKAIQGLDHASKDNGSVDIVVNTPASPSSSLVLSRFEFEPDKGNEGTKVLMVEWDDSGYSTTLGARDIPGKPTGDNTRQDFETTPENDWMVIWEGKDNHNVLAASDNAASLASTARRTYFLLPPGTTVPPLVRITRGSRVCVGSGKESEATDLWTKPMPAIYPTSLGSDAGRAGGRGVLHTLWAKHRLAGLEAEIEAEMKANSESIGLQIALQEHDWVSDHFGIGEPSGLRTSPPYMSSPASPTASRAAMPRSPIGGKLGEKLKGLRLATSPAELAAALQVKTAASSTCATVGTQSTRALDEPVSVGTRLGLRTSIESHNGVHNSLDAVISDSQAVNNNARVDDNSVDADAEDELFALPLSPRSPEMPRSPFSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW32</accession>
    <name>A0ABR3YW32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_006885</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="700" mass="77146" checksum="E98F8584592F05E1" modified="2025-10-08" version="1">MSTTPTATPETLSAPAMPTPTRTRTPKTRSRSGCYNCRRRKRKCDEQRPTCQGCVRRKETCEWGMRVTFRSRNALSLKGGSRKRAGDVRPVVWSDNASSPGNTLDSSLRSRPATSLPAHQSTSTTAHNIHSNNNTHGFLYNDGNEDDSYNSHNSYDTPSAYSPTVSLPPASREPFRYDSNMSAVIAAPSISTPMPTGMENMNTDDSVIATLVSTSGMARGQVDQTTDATVSAWNENGTACEDTAAQPLEWPSHLLSDDHDAPALSQDEEVALWTNWFEEIAPWLDKFDTQRHFQHVLPTMAQTCESLRYAMLALSARQIERKEQEVADAAAEASVAEGGQGDAGNNAHKEKSNTSRTNRRTEDTGRSLALYQQAIHLLLPQLHTRTTAVIAACVVLCVLEMMSCSPKAWRRHLDGCAGLMQAVGCHGFVGGVEQALFWCFARMDVCGGLISSVRTLIPTELWVSGSADANGDLDDPGARFDRSDACGFDMAANHAIFLMAQVLDLLYAGPEAPNDKDKEKEHAGSHRPAPPPVWSEAYRARWLRLWRRVEDWRARRPAELHEILTIPASEAAGSATPFPTLLYSNPAAISGNQMYHTAAVLLLQNLPFSVRFSHLASLSPSPRVPPHSVLWHARQICGISLTNHHHGAWTNSIQPLWIAGRCMSHVSEHRAILALMRQIQRESGWAAQWRADDLVEVWGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWJ0</accession>
    <name>A0ABR3YWJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_007212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="365"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="862"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="891" mass="98370" checksum="0FF62980C54BB6E0" modified="2025-10-08" version="1">MSPTPTSTTPSSGARSPEEQFRVVRKRNRVPLSCYPCRTKKKCDRGHPCSNCVKRDGDNTSTCSYAAPVNRKKNQAASASPDDMQNRIDRLENLVLSLMHTGNGVDAATAASAAGMIPGVSAPNTVSRTDSISSAAKDTGSTQPQDDIDDESDVDDGLATSLGVLKVDTDRGKSMYIGQEHWHTILSDIAEVKNYFVMHRKDLEKSYERVLQSKPATAREAPTFLLGAEATTEGDLRAELPPKSTVLTLCGRYFNSMDNAVNIIHAPTFNAQLRSHWQNPSKTPIMWLGLLYSVMCLAMLSYHKVGDEPPEWKGHAMELASLFRVRTVQCLTTADYTKPVEYTVETMILYVFGEYSSRWDADLGLWLIGSLITRVAFRMGYHRDAKWFPSITPFQAEMRRRTWALVRMCDVMFSHQVSLPNMIYDHDCDTQLPLNIFDEEFGPNTKVLPPSRPNSEPTPIAYMIAKVKLCLELGNILQATTRVGKPVPYEEILRFDTRLREVKEEIPSHLKLQPLEGSQDPLTLIIARFNIDSLYQKIMCLLHRKYLSRARQNPRYAHSRRSAIEASMETLHHLQTLNKESQANGRLRSIKWYVASIATKDFLLPAMLVALEVRFDNLAAKEGREEDSFWTREQRAEMVNILNSTKEIWRPLADGSMEAYKAYNIIRIVLEKIGTAPSEGPRVTEAFVQSGICSVDPPPGAKSTPSDNSVHIDTPLTDPLLDQPEMMAPLNILSGTIPGFGAPPSTTTSPSTAANTAAATTVPATTSMFGSVQTPGGTTYGTIDPTLTAAIDGGLTATDLNGDMMGSMAGFNMFNQAMGSAVPNIMDDTMDFTTNFDWDTLQNYAQSGPFAAADQTFQFFSTDQPPLGTNPSDANTYNYSGTDMPSSGPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX79</accession>
    <name>A0ABR3YX79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_006938</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000043">
        <property type="protein sequence ID" value="KAL1892652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="142"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="579" mass="63259" checksum="E9C4D0DABBAA9FE3" modified="2025-10-08" version="1">MGFLGKKSEADSSPLPTDTEKETRPDTRTPSTPKDISRAVEIDLEKPDETDGNRPSLNERRPLPVLESAENDGRQLDNDEAMVDLEDQNPDHSGSDGTAPTVTGVTAEPLALMDLEHGLVGWDSVEDPDNPRNFPQWKKTYIMIMMGIISTLSPLASSMVAPGIAATMAELHEPSEIVGSFSVTIYVLGYAIGPLFLGPLSEVYGRYPVVILATWFFNAWLLGSALAPSMPALIVMRLFAGIGGSAVMTIAPAMVADLFPVEKRAFTMSLITMAQSVGPAIGPICGGFIVEYLDWRWAYWLLLIVAGTTNAGLTVYMPETYAPCVLQKKAARMRKSTGRADLYPLLNRKMSTRDVLMRSIIRPIKLLTRSAIASLLSFYIATMYGMLYLMFTTIPAVFGDLYGWNVSIAGLAYAPFGIGMVLGLFVIMATNDRTIANLTKRNNGVYEPEMRLPHCVYYAACVPISLFWYGWSTQERVHWSCPVISLLFFGVGIIGIFIPVVTYLVDAFTPFAASAVAANRTAMSIMGAFLPLAGAPLYASLDYGVGNTVLAVIALMMTPLPVIFYKFGGTIRRRWPVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX99</accession>
    <name>A0ABR3YX99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Acetyl-coenzyme-A carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ACC1</name>
        <name evidence="21" type="ORF">Sste5346_006681</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="18">
        <location>
            <begin position="67"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="224"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="16">
        <location>
            <begin position="702"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="19">
        <location>
            <begin position="1530"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="20">
        <location>
            <begin position="1872"/>
            <end position="2190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1225"/>
            <end position="1254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1893001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2302" mass="256812" checksum="D9950E123BCAB61B" modified="2025-10-08" version="1">MTEINGHSAKNGVASKASGSAAATANGKASYAAKYKLADHFIGGNKLENAPESKVKDFVSKHDGHTVITNVLIANNGIAAVKEIRSVRKWAYETFDDERAIQFTVMATPEDLQANADYIRMADHYVEVPGGTNNHNYANVELIVDVAERMNVHAVWAGWGHASENPALPESLAASPKKIVFIGPPGSAMRSLGDKISSTIVAQHAKVPCIPWSGTGVDTVEKDSEGIVTVPDDIYKKGCVESWQEGLERAKEIGFPVMIKASEGGGGKGIRKAISEDGFEQLYKAAASEIPGSPIFIMKLAGNARHLEVQLLADQYGNNISLFGRDCSVQRRHQKIIEEAPVTIAKQPTFRAMEEAAVRLGRLVGYVSAGTVEYLYSHADDKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQVAMGIPLHRISDIRLLYGVDPKTTTEIDFEFKNEESDKLQRRPTPKGHTTACRITSEDPGEGFKPSNGVLHDLNFRSSSNVWGYFSVGTAGGIHSFSDSQFGHIFAYGENRSASRKHMVVALKELSIRGDFRTTVEYLIKLLETEAFEDNTITTGWLDELISKKLTAERPDPVLAVVCGAATKANLASEACIAEYRAGLEKGQVPSKDILKTVFPVDFIYEGFRYKFTVTRSSADSYTLFINGSKCSVGVRTLSDGGLLVLVNGRSHNVYWKEEVAATRLSVDGKTCLLEQENDPTQLRTPSPGKLVKFTVESGEHVKAGQTYAEVEVMKMYMPLITQEDGIVQLIKQPGSTLEAGDILGILALDDPSRVKQAQPFVEKLPELGSPVIVGQKSSQRFSLLRSTLNNILSGYDNQTIMAKTLHDMIEVLRDPDLPYSEWNAQFSALHARMPQKLDAQFTQIVERSKARSEFPAKTLLRAFQKFVEDHVAPEDAGLLRSALAPLTDVLNLYIEGQKVRELNVILDLLNIYADTERLFSGRRSQDEEVILKLRDENKDDITKVVETVLSHSRVGSKNSLVLALLHEYRPNKPGVGNVARYLKPALRKLAELESRQTSKVSLKAREILIQCALPSLEERTSQMELILKSSVVDSRYGESGWEHRSPNLEIIKDVIDSKYTVFDVLPMFFGHEDPWVSIAALEVYVRRSYRAYTLKNVEYHSDETDTPQFISWDFALRKIGQSEFGLPIQSAVPSSPATPTSEYGFKRISSISDMSYLSRKTEEEPTRKGVIIPCRYIDDAEELLSKALDTLTVASKQQRPALRPTGSSTLLPVLEGRRRPAPPRLESNDELSAVVNVAIRDSEGRDDQDIMSIIKPVVEGVKEELLARRVRRITFIFGRQDASNPGYFTFRGPDYEEDDSIRHSEPALAFQLELARLSKFKIRPVFTENKNIHVYEAIGKGVETDKRYFTRAVIRPGRLRDEIPTAEYLSSEADRVINDIFDALEIIGNNNSDLNHMFINFTPVFQLRPEEVEQSLQGFLDRFGPRGWRLRVAQVEIRIICTDPETGMPYPLRVLITNTSGYVIQVEIYAERKSEKGDWVFHSITGTTKIGSMHLLPVSTPYPTKNWLQPKRYKAHLMGTQYVYDFPEVFRQAIQNSWAKAVKHNPALADKQPPIGECIDMSELVLDDHDNLAEVSRDPGMNTCGMVGWLITARTPEYPRGRQFIVVANDITYNIGSFGPKEDGFFNKCTEYARKLGIPRIYLSANSGARLGLANELMPYFKVAWNNPAKPEQGFKYLYLDDAAKKQFKDSVITEEVSEDGEKHHKIVTVVGAEDGLGVECLRGSGLIAGATSRAYNDIFTVTLVTCRSVGIGAYLVRLGQRAVQVEGQPIILTGAPALNNLLGREVYTSNLQLGGTQIMYRNGVSHMVARDDMEGISRIVEWMSFVPDKRNNPVPISISTDSWDRDITYTPPQKQAYDVRWMISGKQDGADFQPGLFDKDSFVETLGGWARTVVVGRARLGGIPMGVIAVETRAVENITPADPANPDSIEQVANEAGGVWYPNSAFKTAQAINDFNYGEQLPLMILANWRGFSGGQRDMYNEVLKYGSFIVDALVKYEQPIFVYIPPFGELRGGSWVVVDPTINPTAMEMYADQEARGGVLEPEGMIGIKYRKDKQLETMARLDPIYSDLKNKIVAAQSGGASAEEIEKIKEKLLAREQQLLPIYQQLAIQFADLHDRAGRMKAKGTIRDVLEWRNARRFFYWRVRRRLNEEYILRKMATVAASASPSATAANRASADFAAQTRARHLTLLEAWSAVPEFKKADREVAQWYEENKKVVQEKLEALKADAVASEIRELIRSNKKDNAAWKGVRDVLRVMPVVDKEKLLKFLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYD3</accession>
    <name>A0ABR3YYD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_006723</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854069" evidence="3">
        <location>
            <begin position="31"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="36652" checksum="C6077EF137785A1C" modified="2025-10-08" version="1">MARLRISSRRSATATATALAVLYLASSAAAAANRTCYFPDGSESPSDFPCSDADTIHCCNSQNACLSTGYCISAEQQPYVISRGSCTDNAWGTGCPAKCAGTNDDPSGGLPISWTGSSNNAGSPLYCCGPLTVDNGSIACANGETAFVLGTSEIMFGVAILQNTTQTNGTSAAASSSVPASSASASSPSTPQSSGSSSGSSGSSSGDSSSKSNSNVTAVGAGVGVSLGVVAAAFATWALYERRKRHQQLQAFMNGTLPPGMSMAHPLQQGPGGPDGAGGAVGAYPDGTYPDGQGMNNLRSGNPGTPFSPAGTTTGTITSNSPSNAGGVYAASNNGNKPYADSQQPLVELSAYPRQFEELPASDEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYI3</accession>
    <name>A0ABR3YYI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Micro-fibrillar-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1892962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="129"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="62748" checksum="F2D069B9D7F90C6F" modified="2025-10-08" version="1">MARLVRPARHRAGKPTGVDSDSSSEEEESGSEQATAAASKAKRPAASSTAAAPKRTGPGRVVTHATLAQAISQDERKLRAELERKAAEEGFITESEDDEPKQKPTKKEEESESEEESDEEESSEEESDSSEDDLQPRKFVLPKFMTKAQREKAAAQSSKTNEPKEEEYDEEKAERERLAAADALVEEQMRKRAEARVASKSKKMWEDSNEAAAAAAAAAAAAAIAAKAKTDAGSGSGSDSDGEENEAAASAAAAAAAAAAALLDVDTEDDVNPEAEYAAWKLRELKRIKRQRERIEEKEKELAELERRRNLTEEERNAEDAGLLAKQREEKEGRGKMGYMQKYYHQGAFYQDASAAEGLDKRDLMGARYQDAIRNPDLLPKALQIRDVTKLGKKGASKYRDLKSEDTGRWGNGLIDNVRSNQNNRYDSWGRERPGWVEGGRDSDGGGYLNRDDGEIKGANAIPLGERKSHGSSSGGDRYRDRDRDRDSSHRDHRDRDDRDRRPPRSRSRSPRRDRDRHSGSRDDRRKRSPPSRDRRDSRDRDRDRDRDRHGGSDKRRRVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYT6</accession>
    <name>A0ABR3YYT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="106"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="509" mass="56037" checksum="D4199F5A12DA37E0" modified="2025-10-08" version="1">MDRYLDVFLLRIHPMFPIIDRQSFSTGVGQLRDGQASDYSLLASTYTVCSLAADEEAGGVSEDGTRFLEAAYVLYAHIVARPSLSSVQALLLLTIALRNRNKDAASWGSLGQAIRLAHAINLQRDDGNGNKDPESELASCVWWSTYILERTMELETGRPSAIRDEECDRPPPSLVREGFDYFGALIRLAQLKTRAIHLLYSGRGATRRNRPIKDLLFEMGHLDRALLDWADTFPESVRPGRDIFCGSDELPLATYVALQYHQTMIALHRPALMSAPGFLRNRINTYCAGTPIRDRLHFSLCIGAASARSIFKATNDLLMYSPVPGRITRLVTADQILLAVLVLGIYVAKVPMSRLNRSDLALVDTFGELVEDEYRLGGHNPEFIKGIGLFRSQLCAYIAGVQGHCLHATAATLSATTAATLCNTTLPATSPATTSNPTSMVTPACTDEFGFDLTMDATDLESSWAHFWNEDFEKLLALPPQTTATEGVETVNIANVTNMYLLGIPQSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYY4</accession>
    <name>A0ABR3YYY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Sste5346_006436</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45783">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45783:SF3">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 11" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PNPLA" evidence="13">
        <location>
            <begin position="9"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="615"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="741"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="783"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="12">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="12">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1893605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="879" mass="98083" checksum="D422D5748E267287" modified="2025-10-08" version="1">MPGDQIRLLALDGGGVRGLSSLMILDGLMATVDPESPPKPCEYFDMIGGTSTGGLIAVMLGRLRMTVDECIEAYTSLSDKVFEKKSHRVKINGKLQGRFDAAKLEDTIKEILRARNLDEDELLKDVAASCKVFVCAMSKQTSDTVCLASYRSPRTKNPYLLNSATIWQACRATSAATGFFDPIVIGPFGEEFVDDLATETERTAQQFQRNKSDLYDEGRYFRFNVNQGLQEIGLEESKKKKEIAAATVRYIESQTVFKQMQASELEQCLLPRRLQFRHEQRRKIFVLHGLGGVGKTQLAANFARRYQATFSSVFWLDGRSEDRLRQSLAGSDVLDWLARPDNVDWLLIFDNVDQDHEQGGTTSVFDIRRYLPGDHGSILITTTLLQLAQLGNPKHAKKLKKVDDNLSKAIFEQWYGGELVLDTAGRELLRLLDGLPLALAQAAAYCRETGLDIASYVRLYNQQWGDLMAPDTEPGSPLIDYDQQRVGTTWTISLKAIETRSKSAANLLRLWAFIANKDLWYGLLQAAAVSQEDEQWPEWLREIAENQAKFLNTVRLLLRYSMIEVQESEQGSYNLHPSLASLYRDQGRLPEAEAMYQRALQGYEKALGSDHTSTLDMVNNLGVLYRDQGRLPEAEAMFQRALQGKEKALGPDHASALATVNNLGNLYCDQGRLPEAEAMFLRALQGKEKALGPDHTSTLNTVGNLGSLYRDQGRLLEAEAMHQRALQGCEKALGPDHTSTLDTVNNLGVLYRDQGRLQEAEAMFQRALQGKEKALGPDHTSTLDTVNNLGVLYRDQGQLQEAEAMYQRALQGKEKALGPDHTSTLVMVGNLGVLYRDQGRLPEAEAMYQRALQGYEKALGPDHTSTLTTVNNLGNLYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZW9</accession>
    <name>A0ABR3YZW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45867" checksum="20C9362C63C2C8C5" modified="2025-10-08" version="1">METRQEEPRQPKKRSIDFLTPDQLRRKREGNVRAQRALREKRKAEMQALQDQNRDLENRLRAAQAALTQAQEQARGQGLQGLNLDPRNVGIDATAPALQLMLGSDMAMPFVPWGENEITSMDVLQIMDDSSDMWTSTLPAVTDLPGNTPDNVKADADTPGDSPHVPSIPPSVPFTTIATDQVWSIIPKHTAPVCVLDDALLTLIHQRRPKDNAPEFQKNSFPSVQSLLNSPPNVTDPDSPDSATSLPEHIEDPRFPVSSTIVHNLRHIMTVPGLPEQIAMLQNVSAIVRWLIAPTRANYEAMPLYLRPTATQLVVPHPPWIDVMPWAAARDWFCSSPSLASLANYNLFSTICNETLCLNWPFQDADILLHCTSFASRKPKEAVDEILLNPIFDRHIKDAANWTVGSKIFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I9</accession>
    <name>A0ABR3Z0I9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF7136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_006230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055560">
        <property type="entry name" value="DUF7136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23584">
        <property type="entry name" value="DUF7136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045988777" description="DUF7136 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7136" evidence="4">
        <location>
            <begin position="31"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="301" mass="31542" checksum="E5527A56549ECCFB" modified="2025-10-08" version="1">MRLSVLAWFSVAYCTLTGPVVSTRADTAAIAPGVVNLDLIFPLNNTYAPFDGPMPIVFGVSRPDIASVLQLKVSYLLSDEPNTNTVYGTSQVFDLSSGSIPSTKNNGNGGYAFFVNFSNASIVGQVGKFRTEITFVFVVDYPGDEKTKETIVPQPLIYDMFFTTVPGAVAAIVPGMEATNSSNSRSNNTTPCMNVGAGSFYFPINITDFITNDGTEFGVISTDRTHHFPSQCAVEVDADTAATIAAGPTTATASGTGTTSSATNTSTANSTPAKMLPSGFVTASVIVAVLYFSMFGGALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0T1</accession>
    <name>A0ABR3Z0T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase eIF4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Eukaryotic initiation factor 4A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Translation initiation factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">TIF1</name>
        <name evidence="21" type="ORF">Sste5346_006304</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000036">
        <property type="protein sequence ID" value="KAL1893801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 21" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="236"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="16">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1893801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="397" mass="44789" checksum="948F309C2B204E2D" modified="2025-10-08" version="1">MATDKGLEDVPEGQIESNYDETVDSFDDMNLKADLLRGVYAYGFERPSAIQQRAIMPVIKGHDVIAQAQSGTGKTATFSISVLQKIDPNVKQCQALILAPTRELAQQIQKVVVAIGDFMSVECHACIGGTSVREDMKALQDGPQVVVGTPGRVHDMIQRRFLKTDAMKMFVLDEADEMLSRGFTEQIYDIFQLLPQSTQVVLLSATMPQDVLEVTTKFMRDPVRILVKKDELTLEGIKQFYIAVEKEEWKLDTLSDLYETVTITQAVIFCNTRRKVDWLTDKLTARDFTVSAMHGDMDQAQRDLIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPANRENYIHRIGRGGRFGRKGVAINFVTAEDVRMMREIEQFYSTQIEEMPMNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z362</accession>
    <name>A0ABR3Z362_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">V-ATPase V1 sector subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VMA4</name>
        <name evidence="4" type="ORF">Sste5346_005496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="231" mass="25441" checksum="058B309D97F531B3" modified="2025-10-08" version="1">MSQTHALSDDQVGQELRKMTAFIKQEATEKAHEIQTKANEEFAIEKSKLVRQETDAIDATYEKKFKQATMSQQITRSTVANKTRLKVLQARQQLLDDLFEAARKKLASEASSSPAKYKEILTKLVLEGAYAMQEPRLQIRVRKADASAAKDALTAAAKEYKKETGEAVEISVDEENALPASSAGGVIIVGGGGKITIDNTLEARLALVEHNALPAVRETLFGKNVNRKFHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z366</accession>
    <name>A0ABR3Z366_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052:SF1">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26024" checksum="B2E80C16E1303E13" modified="2025-10-08" version="1">MTVTEFGVTKGSGESFTPEFRSAVEAALASQTKWLKIDPAATGANPTTGSRAWLLQQIEDPASVLLAATWTTVDQHTEWATTDPDRDTLLPAIGKHLYQPKGDDDPAKPVILVHTEGDVFTNAGEPIPEGKRALLDSPVISVTRMYVTAGKKAEFEKALNDTKGLIEGYTSPNIVRGAWRVDKEKDAATGEDKEEYVLVAGWESREAHYAIADTDIGPKLAAFTSLLDGRDSKHYKRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3C4</accession>
    <name>A0ABR3Z3C4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Sste5346_005458</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 12" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382105" description="chitinase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="15">
        <location>
            <begin position="92"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="16">
        <location>
            <begin position="147"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1895038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="533" mass="57718" checksum="6C2B30456D860C4A" modified="2025-10-08" version="1">MNMATRLPRWRLACLVLLQYSWITVLAKATFADQASASQGGQAAAAANDYTCSKTKACAIGCCGPLDSTGAGVCGAGPLFCGKGCTSQCDWKSECDAGWGLQYANASTCPLNVCCSQFGFCGTTADFCGSAVVSSPQCAATGHSADNRTIGYYEGWNAQHACGTMTADQIPLGYYTHINYAFALVDPRTFHVAAMDADTASHYDAVTNLKAKQPGLEVWIAIGGWAMNDPGPYRTAFSDMASSEANQDAFFESLIMFMSTHGFDGVDIDWEYPVADDRGGVAADFKDYVYMLSRLRARLDGSGRRYGISITLPASYWYLRGFDIIHLERFVDWFNIMTYDIHGVWDSTDKFIGSYAYAHTNLTEISEGLELLWRNNINPQRVNMGLGFYGRSFTMADPNCMTAGCPFTTGANGGQCTGTPGVLSAAEIVKIINGGAKVTFDPVAAVKIVTWKTNQWVSWDDAQTLKLKQDFANERCLGGTMVWAIDLDDGTLINALGSNLARQKANVYNTTMYNADEYLFSVDDSSGSNSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3M7</accession>
    <name>A0ABR3Z3M7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF19">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045130207" description="Fibronectin type-III domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="686"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="791"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="993" mass="107201" checksum="82AC781784F623EC" modified="2025-10-08" version="1">MRWSIVLAGVLPLALAVPQAGVNFGRLNFGHADAVEDAAKAATASATLEAAPSSVSGSAASESSVFEWPTAEGINTSTLLTNGTRITDPVRIAYLTTLHDQVIANMNNGTAVPMNMVKRISKDPPYIHKRQELVADFLGLFIDLILTEYTGEFVKLEAEIGKLFAGGNDAWWDDTDRCRVHFQTQGGAHELIEGYDRGASDPTSKTSDNIGWNNPKDTDPPVLYFDDPDLGMYSVQFTATDTVAWSGLNGTKKCIVQGLCNPQYVFYHTGYRIILNTWQSQGVAADCEYLEDCKGLCNSGVLNQFTTGGDVWGGDCAVPCYDETDDLPTVPDQAPKIMVVGDSISHGMQDDWTWRYRLYSWLTGLGYQATFVGPYVGTHGMSGLDSSEPMAPLLAGETSMTFNVQGGYAGGVSSDFTGSGHAAYWGRQATQDVSQINGWVAQYQPDYLLILLGFNDLGWFVQGPDGLIGQMGNLVENAREAKADVKLLIGNVVQRLFIDGRQDLVDNTNTYNQLLKDTLPSWFRWESPIAYVDVASYYDCGPDSCPDGYDGLHPAVPGEHHIAQAFADMLGNEFDFPGQPYVVPSDLDGRPVSAPTNIKSYAYPEGIFTTWDNMPNNRGYEIRARLTGMTDWWSDGTVYPSTWGSWLSWLEAGQSWDTQVRTRGDFDTVSDWSDIVTVVANPATAPGPSVINTYPNLGPDVMTVNWEPVTGYDIHCYGVIIWDLDTPDAFISTYATIGTEMTFTDLIVGHRYGVWVASYINLSKGSVADFAVTPGGLPASANAIIFGGGVPLPPASLSYTEVDATTMTFTWPATVNAAGYTLYMRNLITDFSVVGSTTDTTLTLGFLFPGVWNYEYCIGSYNGNYESSYGGAGCVTPPICCGYSYSAEHGAVVDVSGNVFNATAMGPNTPPPQVIASNTATPFVLTTGANATVTVPASVIAGNATANATLLTMDPRVGQLYSMYHQAMASLQQNNVSIASLTFASPDTVVQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3S0</accession>
    <name>A0ABR3Z3S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HTS1_1</name>
        <name evidence="11" type="ORF">Sste5346_005430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="22"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="488" mass="53787" checksum="9A23A06018059638" modified="2025-10-08" version="1">MASKEGKEKAKGPAVQLKTPKGTRDWTGADMILRDEIFTTITDVFKRHGAVPLDTPVFELKEVLAGKYGEDSRLIYDLADQGGELTALRYDLTVPFARWLAMNKVQQIKRYQIAKVYRRDQPAVARGRMREFYQCDFDIAGVYDRMIPDAEILRVIYEIFEALKEQIVIKLNHRQILDGIFAVSGVPADKIRAISSAVDKLDKVPWADVKKEMVEEKGLEEAVADRIGEYVKHSGDIPTIVSLLKADESLFANADIKQGVEDMELLTSFLDAFGVPGKKISFDLSLCRGLDYYTGLIFEVIAQPSAAADATAPAAGGKPAKKKGGAEEIQVGSIAAGGRYDNLVGMYGKTQIPCVGISFGVDRIFTIMKAKREKEEGKSRVRETDVYVMAFGGGNFNGLLKERMSIARRLWDAGIKAEFAAKTKPRLPQQFKAAEDVPLGVILGEDELANGQVRLKQLGSGSGEADEKDRGQLVSEDDLVAEIKKLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z500</accession>
    <name>A0ABR3Z500_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Medium-chain fatty acid-CoA ligase faa2</fullName>
            <ecNumber evidence="5">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FAA2</name>
        <name evidence="5" type="ORF">Sste5346_005809</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="89"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="708" mass="77761" checksum="BD93CEA741C2D2BA" modified="2025-10-08" version="1">MSPSEVAAAIAKLSPPPPPGAPYAVPVPNSATPDRSAVYRHWRFRDSPLLETLESGVETLHDAFESSVKHRGNRQFLGWRPWNPTTKTYEEKYVWMTYNEAAERRKNLGAGLVEIHKAAGVTADKYAVGIWCQNRPEWQLTDLAAMSQSLYNISLYETLGPDTTEYIINHGELVCVVASLTHIPSLLKLAPRVPTLKLIVSIDPLDNGEPEGLSKGALLTKMASDHGIKIFSMSEVEEIGLRSGRAIRPPSKNDITTINYTSGTTGAPKGVVLTHRAMLSAVSCARASGFMTPNDTHISYLPLAHIYGRMADWAALSLGARIGYFRGDIVGLVDDMKILRPTGLFSVPRLYNKFNSAIRAATVEAEGFKGSLSRRAVDAKLANMRLPPGKATNYHALYDRIWSPKVRKAVGLDRAVSMVSGSAQLDPDVQTFLRAAFGINFLQGFGMTETCAVGSVQVRGDLSTGNIGGPQAGCEFCIESVPDLEYTVDDKPNPRGELLVRGPILFSEYYKNPEETTRAVDAQTGWFHTGDIVEVNSMGLFSIIDRKKNVLKLAQGEYVSPERIENVYLGACTLLSSAFVHGDPIEACLVAVFGVEPETFAPFASKVLGGDKTMIAPTDREALKKATQDPRVRQAVQAIMDGIGKKHKFNGFEKIRNVYLDLEPFTVENELLTPTLKLKRPQAARAFRKELDQMYAELREQESSKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5F0</accession>
    <name>A0ABR3Z5F0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_005453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="118" mass="13498" checksum="C985DDF4506A2B7A" modified="2025-10-08" version="1">MAPLLAKASFPPLSHIPGSWHTRVTRLVLKYHILKGRRMYYVHALHEVYGPVVRIVPEEVGVADPAAVARIHRIGGGFLKGPWYTKTNQAPEPSIFAMVYPRIRRDGHMAEARRNRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6B1</accession>
    <name>A0ABR3Z6B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">URA7</name>
        <name evidence="12" type="ORF">Sste5346_005476</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="11">
        <location>
            <begin position="2"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="324"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="588" mass="64405" checksum="F010D2FCA449ECFB" modified="2025-10-08" version="1">MKYVLVSGGVISGVGKGIIASSTGLLLKTMGLTVTSIKIDPYMNIDAGTMAPTEHGEVYVTDDGGEMDLDIGHYERYLLTTLTRDHNLTTGKIYQQVIERERRGDYLGKTVQVVPHLTNAIQDWIERVAQIPVDESGNKPDVCVIELGGTVGDIESAPFIHAMSQFPRRVGKGNFMQIHVSYVPVIPPGPHGEQKTKPTQRAVGDVRSAGLRPDLIACRCERPLEDAVIQKIANMCQVEPKQVLTVHNVSSTYHVPLLLRQQKLLDSINGLLELNAPGAPTPSKALIDHGAKMWSEWVSRTRAQDGGNLDTVTICLVGKYTNLEDAYISVGKSLEHAAMYCKKKLNLVWVDSSNLEDTALEEQPAKFHEAWHAVCTADGILVPGGFGIRGTEGMIKATTWARTKNVPFLGVCLGMQLAVIEFARNVCNIPGAGSEELHPGCENPVIVYMPEVDRTKLGGTMRLGKRECVFQPGTAGWSKFRAMYGDDVGSIQERHRHRYEVNPEKMTTIESSGDFVFVGKDEKGERVEVIEIRNHPFFVGVQFHPEYLSRVLAPSKSYLGFFAAAAGVLDEVTASSSGKPLVVKDAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6D9</accession>
    <name>A0ABR3Z6D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="3">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="4">
        <location>
            <begin position="230"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="843"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="644"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1137" mass="125173" checksum="3EA053279009DC2B" modified="2025-10-08" version="1">MHIINVETLMLEEFPRRPQDDYAILSHTWKSVASDEVLYSDIKPNGLAGCPDKPGKHKVKGCCQQAKAEGFKYVWIDSCCIDKSNAVELGEAINSMYRWYRESSICYVYMEDVPNEDDVLEPGAAFSQSRWFTRGWTLQEMLAPVELHFYNTSWNIIAAKQDIIHELEAITGVPRQSLLDFDPNTTQATVAQRMSWASCRTTTRDEDRSYSLLGLFDVNLPMIYGEGGRNAFVRLQQAVMEKTRDNSIFAWGLTDGSTNKAKRRPLSMASTGSDVATDDLVSEGIWASSPSDFSRCGKVVARKPVGGTVFSFSSGRLQIDMTPVSLISPPIKRPDGTFLARSHTRYRGSNDTAATDGQNAASSTPKMYYGLLNCGPESESGSLNVVIGIPLCVATKDKDSNYAPKEYIRPIGYTPFYLNRPVLKEGESWPQESTSIRVEMEAGSRSTSRQVWYSLRYPRKSLALVESYPRSAWRGSTARMPDADDVDLLEQHKKKWYLARFRPVGGEKHELGLGSSEDILLVVCVRLDLDRTKLSVVGSLMTVSQKTLVEKIAGKLPYLRESIYHHKTVSVNGMGMAASVELDTETFTIAPMTTYSPSKTLNAEAEMVHADNNISLPDLFSLQDSLLGSSMRLKSAGEEHSNLLAIRMERLAKVESDLKRLEDERNELVAAITPLQESVAFATAKIDELEVQFRAVERKVEKYVADATANEPPIAQQNWLGELLLARHGVIESCSVCRTHYRSEEMATTDAGSAVHPFRHLYAEEDPIYSIQPVGQMALFCAVAHGRVHETQQLLRAGASADAPIQRQLRPLIMMAAFDGNRTLAGMLVHRGHAKVDVRDKATGETPLWVALKRGHHAAAQFLVDAGANVLAKNASGDTLMNWAAGAGSLSRVRFLIRNGGNALNEIGVQKAPLVAAAYNGNEDVIRTLLERITTTDKEKSDSIVQAALRAAVTSDHANAVRLLLTNKIDSLNIAPLLLEAVEKKSVPVLDALLDSKDVQGLDWQDPASAVAMMVACLENPPDCLAVLLRHNFPVDVVLPKNGPRPLTVAATYGRYEAVDMLLLGGAQVDLESPDELRTPLYMAIKGGHTRTVRVLLAHGADPTKSVGLLGSPLKKAKQMGDKMILDLLENARSKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7A6</accession>
    <name>A0ABR3Z7A6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 55</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS55</name>
        <name evidence="7" type="ORF">Sste5346_004575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OB-RGRP/VPS55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007262">
        <property type="entry name" value="Vps55/LEPROT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050">
        <property type="entry name" value="LEPTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050:SF0">
        <property type="entry name" value="RH04491P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04133">
        <property type="entry name" value="Vps55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="129" mass="13868" checksum="E4E38CE5E4750DA2" modified="2025-10-08" version="1">MTTAGLKTIIALSFVLAVGFLLVILSCALFQVYYPLLVVATYVIAPLPNWICSRCANPDDFVESSGAAILDVGRFFTGFFVVMGIALPVVLAHSGLINMGAMVMSIVGGLLIYGTIISFGMFFQEEQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Y8</accession>
    <name>A0ABR3Z7Y8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SNX3</name>
        <name evidence="14" type="ORF">Sste5346_004769</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Prevacuolar compartment membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07295">
        <property type="entry name" value="PX_Grd19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042138">
        <property type="entry name" value="PX_Grd19_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051074">
        <property type="entry name" value="Sorting_Nexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963:SF2">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="13">
        <location>
            <begin position="21"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="142" mass="16643" checksum="1AC0CD3296ADC856" modified="2025-10-08" version="1">MQTLPESRPQSFDEIYGPPENFLEIEVRNPRTHGVGRHMYTDYEIDCRTNIPAFKVRQSVVRRRYSDFEYFRDILERESARVTIPPLPGKVFTNRFSDDVIEARRAGLEKFLKIVVGHPLLQTGSKVMAAFVQDPNWDRNAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z878</accession>
    <name>A0ABR3Z878_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="139"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="322" mass="35469" checksum="D8ED4F6615EBF033" modified="2025-10-08" version="1">MLEALNEFPQGQHEASSYGQQLSVFTAKAPRLLWFDRATNTQVLEDFPDAIDLKTTLLASAVQRSEKQHSLAKDAQLGHSIGVALGAWLRSFLSWTSERGPARSSLRQAIAGNEPMRKLKHQITYDALVRVVSQFPGALGDRLPVLEEVQAAAAAEFDKKPPADGAEEDDSWGIIHGDFWSGNILLPSDDKLKPDASTAQQLFVVDWEFAQYGHRAYDIGQLIGDLIERDHFRGAKASLDVLAGFVSSYFPSGADDSFAFRVAIHTGVQLIGCFIRRAPRGPLPGTPEQVEQAIQLGTDFIVKGWTKDRAWLEKSVLAPLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8V9</accession>
    <name>A0ABR3Z8V9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SNF1</name>
        <name evidence="16" type="ORF">Sste5346_004413</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14079">
        <property type="entry name" value="STKc_AMPK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="86"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="440"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="513"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="612"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1896780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="758" mass="83564" checksum="885D78C98EE04AB6" modified="2025-10-08" version="1">MGPSRLEDEELSISLPRNQSRRSHAALAAASQGGGQQAPPTINVVDHGSDPKANPETTAASSGKSKKGSHHLPDRIKSTDARLDQYNVVRTLGEGSFGKVKLAIHKSTGQKVALKIISRKKLISRDMTGRVEREIEFLQLLRHPHIIKLYTVIKDSNDIIMVLEYAGSELFDYIVKKGRMAEPEARRFFQQMLCAVEYCHRYRVVHRDLKPENLLLDDKLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGVILYVLLVGRLPFDDDHIPSLFAKIAKGAYILPSWMSPGAATLIKKMLVVNPVQRATIDEIRQDPWFLVDLPDYLRPPAQPFFNTGIDPEKSIKTSDIAPNASTKVQEKLHNEVTDKISKTMGYGKKDVQEALEADEPSAIKDAYMIVRENKLMQINPNFGADNPYFATSPTSGSSSGTSSIAAAVSGSGELDPGASPLGMSSGRSIGSNSTGNSPRPHVSKVGILPSSLPAYHKDYMAGNVSADVTPAPNDAPPAPARTLAEQEETARRLRPHSRSQIRLDESNKRPQGMTPVNPPKKSKPVRWQFGIRSRNVAWDALLCIYKALNRLGCSWVVDEDFDKYNDDEGSSTRGGDDSYDDGYGSSMRRNSRDDITKKYRLPADPWHIQVRWTTEGIRQSAVKNNAASADEVSADKTTVNKNDDDSQHQVVAMRLDIQIYAMEPSVYLVDFKCNGYETAEGFVLEEKEVSSAFPFLDLVAKLILMLADGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z967</accession>
    <name>A0ABR3Z967_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004753</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="539"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="562"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="830" mass="91709" checksum="68481F0764032F5F" modified="2025-10-08" version="1">MSSNGGTSAAAAAAIRGGGRVLLACDSCRQRKSRCDGLRPRCSHCVQSGRTCLYRPTPTNLESDASVLARLADTEARLQALEEKNRMLLAALPTLSPANALAASVGAPVATAAAVGGSPQSMELFHHQQQQHHHLLNQHQQYQQQQQNFNNLQNQSHGPAVQVQQPDSSTPHEKTRAPPDLHTAAAFKLLTCWPRLTINMTIPQLDTQTYLTRCDQADPLLVLPGDGTDEGLRLDDTLAPWQASLALEQLYAPNVLQNLPVGMVALLEAVPILQRDHVVASFAEAINNSNNNGGSTSVSVSHVSDPMDADMDVMDEMTVAAATQLQQFHGGSTHNTNGDSMYDRQHRPHQLNGHQQQQQQQQHRRLGQQPPIDYDRMSFAQLLMLSIGIRTSMGCRGMEVHRQRTPFDPPSRQSLMALSAHTCSLALQKLWMLQAGPTEELVPLVLLLAHYLADFWVRPFHARGLLRSIDPAIKHMAMLQADDPLVTLYARLHFTLESDIITELNGFCTLSSAALLAMPPLETAGASSMVPVSSLLMAASPPTPSTSTSNLSAVDSSAVNGHQQHNPNPHQQRPPQRSPTFHVENHVRLRILLNRILHLLYAPTKAYAQPHELADIVSSLTAGLRTWYQAQPPDQQFVRDATVFSINQPSAVATNMSLRLRETALRYFGCVFLLHRPVLYFFLHKDLEYTVRPPENVRTLHVDREPWVLESCRDCIESAALLIHLSCLTPEERGTSAGNEDGSCVEDIFGSWCNLQMLFAAYLILLQVRSVPSLMPVFRNIGDMDALLDKVERAFTTHPIHKSLVLDKTLAILQDERRNFEAASPLAHMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9X6</accession>
    <name>A0ABR3Z9X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_004209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="125"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="466"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="595" mass="67226" checksum="E5814B62F606418B" modified="2025-10-08" version="1">MYSGALTIPDDAFRDELLRTYVYVVYPFMPTIDLDDFLGSITTADDRNPVSLLLFQAVMFAGVTFVDAKFLRARGYDSRKAARKAFFSRVRLLYGLDYEQDRLPLLQAVLLMTYWYDCPDNDKDTWYWMGIALSLAQVSSYHREPLMPSVKQRRLRRRIWWSCVIRDRLLALGVRRPSRIYNEDFRVDPLTVDDFDLRMPSESVVRLLGESRFAASEPSARLQTAVLCVELSKLCTCLGRILHSQYSLTGSQETRSDYLRKAVVVPKDSSTQLEDLALCDAELDEWLTTQDIRAKYTPARTSRESRANVDDATRVIQLHQAQLHMIYLTTITVLHKPQVFFSGSDRPDNDQTNAQRRTSKAKIMDAAVAITNLAHNLKANDQLRFLSTSSVPAFLSASLIHLMDTRSPDDDVRSISIGRFCQCVGALQQLQDIYSSADYAIYFLRDVLKNANIDVPMVKLALMSPTSNETTTQQQQRTSRSTSGCASSSTRIWTPPYQNQPASQNQQIIYPDLPLGRDTKNYSNSGIPNQPQPFLDGQLNPMSAVNFFGGAQDSGDVIFDPLLMNSWLDIDVTVPTLNGFDVDGNSAPMNTTSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAB7</accession>
    <name>A0ABR3ZAB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Biogenesis of lysosome-related organelles complex 1 subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="12697" checksum="DC82CB0A272224DF" modified="2025-10-08" version="1">MAAASIISPSRQSTSDLIDLNSDLFNFSVDLIDLQSAAPDVGISGVSADVTAEGLETARQQAPPRIMAKGDRSVSKCQGLHAHIHGTAMRLEERIAEVDELHEAIAAAKRDGSLTPPNHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG1</accession>
    <name>A0ABR3ZAG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARO4</name>
        <name evidence="10" type="ORF">Sste5346_003944</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="9">
        <location>
            <begin position="47"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="378" mass="40306" checksum="68592BBAFCC55F09" modified="2025-10-08" version="1">MPGRDASPLVVDNLRVLGQDPLIPPDLLISEIPITEAAVETVVKGRKDAVNIIMGRSDRLLVIVGPCSIHDPATAIEYRDRLAGLATTLQDDLCIVMRAYLEKPRTTVGWKGLINDPDIDSTFKINKGLRVSRQLFCDLTSGGMPIATEMLDTISPQFLADFISVGAIGARTTESQLHRELASGLSFPVGFKNGTDGNLGVAIDAIGAAAARHHFMGVTKQGLAAITRTSGNEHGFVILRGGTHGPNYSKEHIQDAKAVLEKKGQKLAIMVDCSHGNSNKDHRNQPKVAATVAAQLREGEKAIIGVMIESNIGEGNQKVPAEGAAALKKGVSITDACIDWESTVTVLNDLAAAVRERREIHTGAAHAATPKTTLLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK2</accession>
    <name>A0ABR3ZAK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vps16</name>
        <name evidence="5" type="ORF">Sste5346_004306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="504"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="829" mass="92545" checksum="C5B189B82860D648" modified="2025-10-08" version="1">MDTTHPTAGWEQVGDSFYRKVQLYTAVFDRDLDLDNYAVAGAPYSGAIALCRDDNKIMAYRGGQASKPSIDIYSSAGKPIRSISWDKVSEIRGLGWSDDEKLLIVTKDGTVRCYVDLQGEFSQFSLGNGAEEYGVESCRFYDSGLVALLSNNTLITVNSYDEPRPKVLAACPDGRVHSWALIPPNHTLSRSVEALLSINQTIYVVDATDCEDRFLDVGPFAHVSVSPNGKFVGLYTETGVLHVVTSDFQTRLSEHRSKSKIPPKYLQWCGNDAVVIAWEDEVHIVGPGGSLAKFYYDSRIHIIQDIDGVRVITNNVCEFLQKVPDVTEEVFRFGAESPASILLDAVQQLEMQSPKADDNIQLIRPNLTEAVDTCVNASGQEYNVHWQKQLLKAASFGKSVLDIYNSDDFVDMCDTLRVLNAVRYYEVGLPLSYDQYQRLGPDSLIERLLSRHEYLLALRIAGYLHLPTDKIYVHWACAKVRTGSEPDEALCQIVIDRLAGKPGISFEEIARAAYDEGRGRLATELLNHEPRAGRQVPLLLSMEEDELALDKAIESGDTDLTYFVIEKMRRKLPLAAFFQTVNSRPVATALVESAAIRDGDNTLLKDMYYQDDRRLAGASVFIREALRQPDSRTASDKLVLAAKLLADNQKESAFELGALKEATTLLRMQEAFDRDLTDSFTGLSVNETMFKLIRLGYHGRAKKLQSEFHVPDRVAWWIRLRALVAKRDWNEIEDIAKAKKSPIGWEPFFNLVLQAGNARVAAVFVPKCTGLEPGTTISMYEKCGMKVKAAQEAVKIKDAEAWNRLLESAGRGTAEGREIEHLGHGVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAQ1</accession>
    <name>A0ABR3ZAQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="206" mass="21849" checksum="AAEFCC21E883DA3B" modified="2025-10-08" version="1">MVSSNNNSPFAADAETASVDEKNQNLSTIETATTTTRYLTEKPSKNSMASATVIASTSTSSTHEKNGGRLSTTSITEGMPRTSDLSTPSSVHHNNPFDTDVEAMITHTTSEGTSNGCTGTGTGNSRRSIACRGLGDSQVWPGQAHWKKKAKEQKMKRSCSCLSRLSKRNRLIIKVLIVLLVIGIAVGVGVGISKPLGAPIWGQKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBU9</accession>
    <name>A0ABR3ZBU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_003548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21627" checksum="629256296CBB8C32" modified="2025-10-08" version="1">MDETGQESPGPGLPEHPPAALLTCSKKFIDILQTLTPADTLGAGTAKHADTETLLQVLSGYLALMRLFDVLFHGVYQTISKMALLPPVPYEALRVRSVLRIGGVSALQDMPLKAYAVGILEAIYGQMRTIEKYLGSSTQYPGSGFTTNAVSETVPTESPYHYANRFDHVNAERILQRINGRIPGYDVEREYAVMAVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBY9</accession>
    <name>A0ABR3ZBY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004223</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="192"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="367" mass="38845" checksum="22CF4B990FB34D8A" modified="2025-10-08" version="1">MASPYPSPSFNIAKKKRTASDANPQSPALKRRKASNISAASISAVSHPLRQTSFPPEDANTPFSARSPSVDFNDNASFVSGGPSSVAGGTASVSTKKKRGRKPKADKLRDQTPSVVGAGGRGTTAASAVSGTSGANGGPKSSTGAPGDAQGGGGGEDDDNDGGDGDMPDSGAATAKRTDEERKEEKRLRAALVACMDADQYERISAWRAAKLPDAVIRRLVNATVSQSVPSSVVTAVRSVTKYFLTDLITSAQTIQDEWIAAGQEPQTEDNKPWPGMVLARGEPEVAALYEKQSSLAIPEWEPETADHILREPPKGPLRPDHLREAWRRYKASVQSKTAGALDLWHTQQGTGVERFPARTGGKRLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDQ4</accession>
    <name>A0ABR3ZDQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_003208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="225"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="460" mass="51699" checksum="3E354E1ED1C8343E" modified="2025-10-08" version="1">MAASREGQGAFFEAMSTQGGIIIHETPKFDLESYIQNYKGPTRYDRLLLIGRCSVPLYLDALKAAVAEAQKSHDVNRYREAWGYLHLAAPNDPDARLNKNWMESTEAANNAETRRLERELKVYKNNLVKESIRMGNEELGKHFEAIGDLVGATEAYNRMRPDVSTPKHIVDLGKHLVSVSMQRKEWVSVVGQLNKITGLQGTDEEKLMQPYIKSMSGVALMGQEHFEAAAKCFLEVDSSSSASISTVTDGFLSANDIAVYGGLLALATMNRNELQTKVLENSRFRTFLELEPHIRRAIAQFVNGRYAACLSILASYRPDYMLDIFLQRHVNTIYTRIRNKCITNYLVPFSCVTMESMNAAFAEPGESIEKELAAMIQKGLVNARIDSINKLVRTVKEKPRVKLHKEALEALSKFETDALDRMRRINIVAAELEVRGTRKGQGNLPELNDNWFDSATPVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDR1</accession>
    <name>A0ABR3ZDR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_003169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AVL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018307">
        <property type="entry name" value="ABL9/DENND6_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051731">
        <property type="entry name" value="DENND11/AVL9_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017:SF1">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09794">
        <property type="entry name" value="Avl9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="113"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="719"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="838"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="660"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="725"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="838"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="891"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="926"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="937"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="968" mass="105435" checksum="10F491416AB532EF" modified="2025-10-08" version="1">MDTTTTPIPPSEEVDGHAEAVESKVDVATDALVAATEPVAEEVVEVTKTPSAPAPAPAPETAKATASSIHLQPSVTPIDTTGAAAPSAYLPPLTPSASQAPRSPASQAPGFTPLLCVVDFHHARGPEVEMWFGVSLSAEDPAVQYDWPLLPFMALSDGAHASTEDFSYFTLLKPATADTPATSLFGIACTRQIDAAQLRNRPADVTRSTVQKAVVVIADSPQFFGMLKERLSIVTKAWFDQREFTDVDILRRFQEALAEEKARGALGGGGISSSGSGGKSPRLPNDDEDRDQYLGMSLRELVHEFRWQTLVLLKCCLLQPKMLFFSSRCEHLCMIQFSLVSLIPGLLRNLQDCAGPELNSYSEKLKKPTTLKTSDRSSLLTYMGLPLQIFGKGSLFGPYTPLQQLDVLADVGTKSYVVGSTNSLLLQQRDRYSDILINLDDKTVNITSTSLRTALQLSASDRRWIDFITQEVNDTWDDANPGRPKTMGYVGSEEFIRLQFEEYLLSLISSVKYHNYTTIPNSRTGRIPAPPLPHIEGDPSIDFGVEFVEYWSHTENYKLWSANTDSHIFEFVEPKHPCAGGLSIDDVQRRIAQQVQDLHLDERFAQGKEVLGRNIAAGREKASTLFNKLYADMETLREAQRQRAEEARQRQQSEKAQQANGNGDQSSVNGNSHANGEAKQGVTGVDLNKAQQTVQSAGARATAYMSSWASWAGEKRKNTGWGRLSGAPSATSNGSTSNNNGNTNSGMTSPAVGGSGSWSLLGSSRRGNRNTMSSTISDASSERGLRMSVSSFMTGTSETNDKLLPATPSVQTPATFTSAASSIHDFPPDLIIRNLDEERPIHPPPKDLPPKDLPPKDVAPTREVLFSSPDDSLADVTATAATNAVPEEENVWDKDAKDDIIPPIPHPEPLEEENTTAQSEFEQVSLDEKPENKKPEEVEEKSEDEEKEQPASKHAPSRSVGSKVMLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP2</accession>
    <name>A0ABR3ZFP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable Xaa-Pro aminopeptidase P</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_002874</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="10">
        <location>
            <begin position="323"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="12">
        <location>
            <begin position="552"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="614" mass="67138" checksum="0DD3C5DB3570E2AB" modified="2025-10-08" version="1">METVNTGARLEALRKLMVENKVDIYVIPSEDAHSSEYIAPCDGRREFISGFSGSAGCAVVSFDRAVLATDGRYFNQAAKQLDNNWTLLKQGIQDVPTWQEWAATESAGGKVVGVDPTLLASSTAKKLAEKIKKSGGKDFVAVPTNLVDTVWAAERPAHPSEPVALLAEKFAGKDTKGKLADLRKELEKKSAAGFVVSLLDEVAWLFNLRGNDIPYNPVFFSYAIVTPDEAILYVDKTKLSDACQTYLAENNVTIKPYSAIFSDAKQLGEIAAQGKTAAEAKKFLLSNRTSWALVLALGGEDYVEEVRSPIGDAKAVKNETELEGMRQCHIRDGVALIKYLAWLEHQLTTGVKLDEVVAADKLEALRSVQEHYVGLSFPTISSTGANAAVIHYQPERGSCAVLDPNAIYLCDSGAQYLDGTTDTTRTAHFGTPTAAEIKAYTLVLKGNMSLDMAIFPKGTTGFALDAFARQFLWQEGLDYRHGTGHGVGSYLNVHEGPIGIGTRKQYADVALGAGNVTSIEPGYYEDGSYGIRIENMAIIKEVKTTHSFGDKPYLGFEHVTMVPYCRALIDTSLLTEREKRWLNDYNKNVVDKTKSLLGDDELALAWLEKETQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGA7</accession>
    <name>A0ABR3ZGA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003253</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="96"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="541" mass="59648" checksum="5BDB5377144DECDF" modified="2025-10-08" version="1">MADLSDKPEVMHSLSHDEHAPHTIGDVNSHGSDAPEVIDPEKQVPAPDTKEAELVGSAVATARRRDLQPPAFLVGMSAEDREVLEKKLKRKIDFRLMPMIILMYILNYIDRNNISAATLGGLKTDLNLTGQQFSTAVSILFVGYLLMQIPSNLFLNKTGRPAIYLPICMIIWGIISGATAGCHNAGQLYAVRFFLGFIEAAYFPGCLYYLSCWYTRKELGFRTSILYSGALISGAFSGLIAAGVVGHMDYARNLRAWRWLFIIEGAITVVIAAAAFFILPNFPRTTMWLSEEERQLAAWRLEEDIGDDDWIDSKHQTFWQGAKLAFGDVKTYVLMVLLFCIVASGSITNFFPIVVGTLHKNNVETLLLSAPPYVLAVITTYCNALHADRTGERFWHIVLPLCVAIIAYIIGVSTMNIGARYLAMMLVVPGVYTGYVVALSWISNTMPRPPAKRAAALAFINAVSNTSSIYASYMFDSSFAPQYKIAFSVNCVTAFIAICAAAVLKFMLVRLNKKLDRGEYVKGAINAVPGAAAEHGFRFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGC4</accession>
    <name>A0ABR3ZGC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_003033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000013">
        <property type="protein sequence ID" value="KAL1899111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053002">
        <property type="entry name" value="Metalloproteinase_M10B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021917">
        <property type="entry name" value="Unchr_Zn-peptidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054:SF2">
        <property type="entry name" value="MIP04191P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054">
        <property type="entry name" value="ZINC METALLOPROTEINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12044">
        <property type="entry name" value="Metallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="544"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="658" mass="72493" checksum="1783760CBE50C82F" modified="2025-10-08" version="1">MAGLGSPMTNGGSRALPVSPYSPRITNVTDNSWAYQKVLIINGTIGDGTQPQQSLDGVVTVSRLDDGFPPVQWPVTDSHFKALVYLMPGANKLRFDFASPKLANSGTSNPIHSSYITLHMVPPTNSPPLQLAIMLAKDSPGTFDAVPARIEREGNGLETAIRKFRMAAYLWQSFTAEQMWRNRLGRRVFRFEEEWTQGTSNLRDREFGTMRSEARIHVIRSDKTIAELRSLDNTQQNAKAKNRDAQYGFAIDAVRNYFQPKAGQTLYVSVLLLDAHWDKGAQMITGHAALGGGAGDIRVGVFGSHGMQSYPTCFEEVVPAFSDCTPTDLNYVGNDAGESGSSWEAANIGIGAHLHETGHLLGLPHRESGVMLRDYVRFNRSFLTREAYSTRTKSKGGLVLEKDECTWHRLDCLHFRTHPCFKLPNDPPLQVDDSVQAWPIEGNCVAITAASGVAYIELHAEGDSVCKSWIEYPLDNGAPLQRQVVLTEQDIRNRLPEAKRRKDPIKIAIRAWGGGTLVIDDVRHLVSKESSTKLSGGILMGKTAYRSAKLGRGAMQGTQANEVIFTSAQQQNRVLSRVVFYHGRALDGVEFVYDDDSRQLFGKRGGKPGGDTFEMDVRRGEYISGFNVRSGAWIDGIQILTSLGRRSPMYGNAHGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGM8</accession>
    <name>A0ABR3ZGM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021905">
        <property type="entry name" value="DUF3517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12030">
        <property type="entry name" value="DUF3517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="2048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2219"/>
            <end position="2239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2658"/>
            <end position="2694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1333"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2219"/>
            <end position="2232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2694" mass="300603" checksum="1ADAB6F16BC3ECD8" modified="2025-10-08" version="1">MERESRSPETELNEGAGSPEASSTRPNPFEGGDESLRKRRRTSLQVDSRGRSVESTTQSPHDETPIVDTIDLSSPPANDDELDDSVMIMDAAPDPSSPHTPENNPTHPASGGIRPPPGFEHLTRQSTGPSPRVTLSLRNSAPRTLDTIPSSPPASPTPSARPNDRGAVTDAATSTVEVLDDSPMASPNGQAADGSGAAVVGTALPTAHETAASSATARSRTASPQIEIIDIVSDDEDAGFGPAEPDVTLLSEDPGVPPNTLLPDPSGSFPYLSQGDAPSDIMMVLTGPLTQDLIWGTPNLRTPGFGASDMGTRIKILQFCAAFARLAAFFVEFEVNLLQRFSTPESLQSRDNISSFYLLALATLTKRDISLKDEDRMDGAFRSDNTAAIIEQFSSFHQTERGGTLRLLYRLLELQVIVMPVYPKIIESFSQVCVVAASVTREAYRNIAREGHAPFAVAAEKDTLALGQKIFNTASAALDTAITNHITSLGQEYASHCIAALGDLIYINLKVDEQEAVRLATSIEERYPMPPDCVPDAFAMKSRFTMFCRLIMNSQMQLRLMAVTNLCQELVSCWRRYGDQAQEHLQDEHILRYVTDVLASTGVVSYLLGPTCHPEITTESGNIIGFLAVTRTYTNSHTDLFWQTVTNTQDPRICEALIRTASRIVTLFSYEAAVYFCKGFLDVPITSFTHHMRELCEAFLRHVYSKAPQEMAASMDSIIPFDVCLQLLRESSVPSATGPVAYPEVQSFAIDKLRECLRTIPLDLDQRQSLYQTSLLDLTQKTRTTLGSLCAITIINRHYGGHDLSFLTTEHDLTKLVVDELEDAIEKGRNLAIPAVISGPTNSPRRDMIFSILVSHPYTLTPELSSRLWDMMPGLKAACKEDRNASWSIFIACARRRPQENNSFLTQCLSEFLPKLPPSCFCESLLEFLRERLLPLLNDVACSLFDVASTKGQQTKAVLDEDKSLDRITLEQLWRIVLTAPPNTIERHATHFLVKDVYIDSQCIKAFPLYRSRKIHLALVSRCLEQLSSAAKNIKCAASEQSTRSGDVNNSNAELTNSASFIYEQELLFIRSLKVLQEFLHLYRASSQFSTPDLRPFITDNLNSVAGESAELKYQSFDGDNQTEVKPLNIGRQNTAASLLASLKEATGFDNYRIYYRGQAFAPKGGDICRSLEELRIHNGLILVKRDVDPDEDDTKEPYTGGSPVETEILKHFQELWGYLSMEEQLSSEIHEFLVQLTIDEDFLRRFDKEDLSYTDVFYIGQPYKSLYTLHALREYLVLRNRTETEATTVVSSSCESDDAEAQMRTPDSNDVQAQAIEIEIATETAVDPEPSVPKDSESQGDKLPEAACKATPALSYQSALVVAIKLITAALCDPSVTELSANASLQVELNTKLLHMLNFALSNTHLGNSAAKSLDAKLLNRLMEVLSPEYQGRLEGSVRLVGLAFSVTMNACVLSREFWDAFRNDEKTASLIERLLLLDGRLDIRQLATVQIGDKIGSRHAMATVSPSEFREFFWPVVLAIVPKAILEPAKCEGVFNLADRLLSDLLEANSPALDIAALLTTTGDLLLSCTTSEDVTQPECADYAMFGLTRLFNSVYRASQNLDLVDTIPSNFMNKLFWNHLFPPWRNNAASVDGTAVSRRSYPRIVVSSQTRALLMKVISDLIDDNPSLLPIMIRNLDQLVPCEKSEDEEPYHYELPSMFEREKALRAPCGYVGLRNLSNTCYFNSLFTQLFMNVPFRQFMMSVDVRDEGDTQSLLFQTRILFGFLQDSIRRFVDTQMCVGSVKTYDDTPIDIHNQMDVDEFYNLLFDRWEGQLLSENDKKAFRSFFGGQIVQQVKSKECKHVSERLEPFSAIQCDIKGKASLQESLRAYVEGEIMEGDNKYNCSSCDRHVDAIKRACLKDIPDHLIFHLKRFDFNLRTLQRSKINDHFSFPHELNMRPYTIDQLSNPDEEQPADIFELVGVLVHSGTAESGHYYSYIRERPTSKENESWVEFNDDMVSNWDHSLLESMCFGGTVDRAANQFGVDGNNGVPPEKVYSAYMLFYQRSSSLAKEQEALAQSGRFSPAKADIPEALSDHIHNENTSLVRRHALYDPQHLPFVSKMLNQVQFVMPGGECSANHRLENVAIQMALSHLDQVASRTKDTPDFQTLYNGISAMGQKCALCSLAIFDYFDARPEILKQMVQRSLDPDVRLEMGQLIIAALKSIKEAFPVSYTSFEEDPEMDTDEDEETQGVPHGRRTELKRNSTIIHSAAFMMQTLWEVFHLVSRSWNEVFGFMQAFASMGREEVGIFLDLEGLRRTILTISADTAFPLDAQYSRMVLMLQRRTRPPSFETVIALFHTLLVGMYPIRPAIRAEADMYIDDNTSRFQMALDSPDEDIPMSRHEYLLMGRDWNGDFGNVFVDKLICIDQNPQATSSIIAHLMATHPAMESKILTTLRANITSNAAAAPQSPFLRAMIVFMQNVRSPESATRMMAHLSQQCRGVAHGEGRAYFETMRALYRGTATAPGQVDLAAVFNALRFIPMWVPGLLCCFDSTVISNVEAFLQDNIFLFGPNPQFDEDEGGQERAAALRLAVKQLGVEMFKYIELAFIQRDAPIGGTVVGAVQRVISECSPYYSQPNDEPEDELSIRFMQLSTTIPDLINRLIIDDIEEDGSDWNSSHCSSDVLDASDPLDSLGDTSMQTAGEMNDADMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGZ7</accession>
    <name>A0ABR3ZGZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002989</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000012">
        <property type="protein sequence ID" value="KAL1899587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="383" mass="40619" checksum="E760A6060CC3EF4D" modified="2025-10-08" version="1" fragment="single">MSSHPSHHAGLPRLSESSSMSYSGPSSYQHPPPPPSSQHQHQHQHQHQHQHQHHHQHQHQHQQHQHQQPPPPTSSISSSGHSSHQYYPSHSSQSIGSHQGPGNPGIGVSDLYHPSPITAQPPPPTNNSIPSLPSMRTIDPLHPSSSSSLHSSPYPGPPSLPPGPLPFFSIPPPYGISAHGLPSFSSYGHHHGHSSDLRMPSFAIGGLRHKKEIKRRTKTGCMTCRKRRIKCDETHPTCNNCKKSKRDCAGYDPIFKQQPNNPAFLQATAHVSPHDSSTTTTTAPASTARPKSPPPVPYSSVVSSSAASNPVTNLAGIKSPSIIGGPSSLSSTSSSSGSAVSNYYGATGPSSTTSSSYQSNHNGNGSTNHHESNGNGSHSSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHP8</accession>
    <name>A0ABR3ZHP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA recognition motif-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="52187" checksum="5935D6546D3FED66" modified="2025-10-08" version="1">MATRPGEENVATLPETDDPPHHRFNKGSYVYLFENAQEGRTRIEIANRPGTERQDAFDGFLDATAVTYSYKHSCMVSLAVIAPPPNQDEWHLPTYDPSNQNIYHYPLHAVDIYFWTHLDALKFVNGVRRLLPTNQVDIRDEPVAPAPPPPPPQPKHYPAPTSNDNNSGSAGPASGAGSNNGLSHVVQKLEAVAINGGPGGGTPAPRSGPVPAAELNFAGPPTSAISDERGRSTSPQQQQPAPAAFAYNPAAPAAPETIRPREKTPPPEDVAQNPLHQRLYQDAATPFSPGLVVPAGLGPLSPGIPPPSLHSPPGAPSFPAPPAYSSTPPTPAGVPQQLQQLQHQHLQQQQAAQQQQQQQQATQHPGLLRAATMPVTSPSPFNPAASFPAFSPPPTTATAPPPSTTAAGATATPAIFQAPPEAGFSNYNYGKAGGAAAGGTPDFSIHQQLYRPTNGETVSHSPKQDPRGKLEETAGRLEKGMTGMLKKFEKRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI72</accession>
    <name>A0ABR3ZI72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="57528" checksum="C6DA22D9C4FBBA61" modified="2025-10-08" version="1">MRPYDAPVMLPPVLTPSVTTTPTPKTVISSLGGRTAEPRALKSRAFSGEDINYYFDKYFEHFHPHFPIIRSRDPDKCYESAPILFWTIMVISARRFAKDDSVLPFLTESLPSEVWGAMGNPPLPLGVINALLLLCAWPFTTIRFMRDPSMIFSSIAMSSCFMIGLHTGRGEHPELANPNFQIRNTDEEATFTWAGFNIISQRVSSYTGSPSTGQFFNKTIENILDRSSPVPVPINFIILLECARFSNRVSKTTCASLEENRGISHHIVDMFEEEFDKVQRLLFPGISELDYFTLLSTLLDVQAFYFMPVTGFSSEIFKRNVLKAYSTSQLVVRQALKLQDELGFLYYAPHFVCRTLLASACITLNVLLSPYIQDMPVHAKDALMHDAITAVKTCSVHDGDLPSRASKMIESYWSVHHLKGPMEIPMKDVSQFSSRLGTSFAFDYIRRWKRDIEASRTSATNAGVKRQAAGTPTASIDLSTIQPENAQLIDWDAFMDDFDWSFTPDYFNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIH0</accession>
    <name>A0ABR3ZIH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 1, mitochondrial</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">PSD1</name>
        <name evidence="14" type="ORF">Sste5346_002525</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 alpha chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="12">Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 beta chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5044941798" description="Phosphatidylserine decarboxylase 1 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044941799" description="Phosphatidylserine decarboxylase 1 alpha chain" evidence="12">
        <location>
            <begin position="512"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="12">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="12">
        <location>
            <begin position="97"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="250"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="511"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="562" mass="61958" checksum="B9322B26718F10D8" modified="2025-10-08" version="1">MASAPSRLGLSRGSFSKGITTGRFSVSLSERQILFNPPRRLVINTSPFRFYSQKAFRRPRFSARLRHALKNSKIQWYRIPVGLGIGFLGLVQFYKVRNRQAAEENGGEGAVEAAQKPKKRPRIRPDGPWQVQVMSTLPLKALSRLWGRFNELTLPYYLRVPGIKLYSYAFGVNLSEVEEPDLHKFPNLAAFFYRTLKPGVRPIDPNHSALTSPSDGRILQFGKIEGGDIEQVKGMTYSLDALLGKHTPAPSIINGQPSSSASSTSSSTANLRAASTMTTTAASNKGQTNAALTGDEELVRADEEFAQVNGISYTLPGLISGPDVTDRPETELEDQSVRPSAKSISEVQADLDLPWYTQLLSKDKKSALYYAVIYLAPGDYHRFHSPTNWVVERRRHFAGELYSVSPYLQRTLPGLFTLNERVVLLGRWRWGFFSYIPVGATNVGSIKVNFDRELRTNSLTTDTAADRAAEEAAQRGEAYSGFAEATYAAASPVLHGHALRRGEEMGGFQLGSTVVLVFEAPEPDTLGVEPGAAPDKSTPGWHWAVEKGQKIKMGEALGFVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIZ5</accession>
    <name>A0ABR3ZIZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calponin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SCP1</name>
        <name evidence="3" type="ORF">Sste5346_002477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21210">
        <property type="entry name" value="CH_SCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050606">
        <property type="entry name" value="Calponin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385">
        <property type="entry name" value="CALPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385:SF14">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="726"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="817"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="847" mass="94265" checksum="948A4DB2F5027FCB" modified="2025-10-08" version="1">MASVTSLDGDLRKMRLDKYTPGAAREARSWIEGILGEQLASGDLLESLKDGVALCRLANMAIPPPGIRFKQSAMPFVQMENISHFLRVCQAPPLNLQQHDCFLTVDLYEGKDPAQVLQCLGAFSRAANRVNPSAFPTAIGPRAGGGAGNRNSVSSPSGPTPASPPGRGTTPTSGRPMSSIYTGRTPLAPTRTGGDGAPGSVAGRWSPTKANDSSNRERSASPGKSPTSTSSWSKRELEGSTAPAWNIAQYGYMGGASQGNLGISFGGRRQITSAGPSVPNAAEKDRLRREKEAEEARQKEEEERQRAEQEAEEERARQEEQLRWEEETRRQREEKKRKAEEEKRKWEEEERQWKLTEEARIREEEEAEARLAEEREQRLRSSNSGKSASGGTAGAGGAGDPRLRGQFLSQYQADQPKDSTPEVYSNRVRELEKELELARQREQAYERERQGRSSGRPAYEDERARSKSRGARSRSRPRAANANLQVSPPVRQESWSRNDKEVLRTPRSQSRHRFADAEPQQQQQQQQQQQQSDFSPPQRHGDRDDDFMPQSGQQAYHQQQQAPPPSKSPRPLPDPRSHYSQQQQQSQPQLPPRMQNQRTGERQQQQPPPPQQQQQQSGPTSFFQKIRTHRTGEKNPPSNENINTNSGSTSPLRAQRTGDGPNKLTKSHGRPLPDPSSYASSPQQHQQQQPPPQPLQQQPPQPTYARELLGGGVAEHDAEDRRRRQQAYNPQQQQQPLIKQRQPFRNAPPATNSSPASGGGGRPGGAGKSLLEREMEMERQRQREWEEAQRATAAAPRQTNNVDGVDGRWDVNQWSGYTGGDGQNRGSQGIGAGRRQIVGPRPLPGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ88</accession>
    <name>A0ABR3ZJ88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002428</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF28">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE (AFU_ORTHOLOGUE AFUA_8G02210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="82"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="371" mass="41248" checksum="E0F70BDB032C7B2B" modified="2025-10-08" version="1">MSTTTTTINTKTEGASEPLKLSVAYDEKLHEDYKYAAYLPVYDEKTTFPPLKPFAFHDRGLVANKAKPNLLPTDPAAGVTATRLTPAIGTEIRGLQLSALTDLQKDELALLIAERGVVIFRDQDFKDAGVEAQKAFASYFGPLHIHPVGAHVKDNLEFHDIYLGPDNEYRTRQRDNRLTTTGYHSDVSYEHQPPGITILTLLSVPPVGGDTAWASATAAYERLSPPIRTLLEGLRAEHSGFPQADNARRDGKHVRREPVKSEHPIVRVHPATGQKSLFVNPGFTKRIIGLKNEESDALLKLLFKHITFGQDFQVRVKWEEGTVALWDNRVTSHTAISDYNVHNPQEGLRHGVRLTTLADKPTGVHGLESTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ8</accession>
    <name>A0ABR3ZJJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vacuolar protein sorting-associated protein 62</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">VPS62_1</name>
        <name evidence="1" type="ORF">Sste5346_002313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009291">
        <property type="entry name" value="Vps62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48171">
        <property type="entry name" value="DUF946 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48171:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06101">
        <property type="entry name" value="Vps62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="360" mass="38406" checksum="735CD9AF49899DFA" modified="2025-10-08" version="1">MPSIRQLAGVLAAAAVSNAAPAVNNNKRQTTPLPAYALTYAPISYLYSGESWWPSDVATHLANVIPEVDYVAVPGFTTAGSVTLATLNAQSSSVYLTSKDNVDTSPAWLVSAYGKPTTTTGGYSAAPGTIIAVQKNSTWVDVFYFYFYSYNYGGKVLGINFDDHVGDWEHTMIRFVDGVPTGMYFSQHGAGSAYTWASLSKGTGANAGRPLTYIGTGGHANYAKPGTEDYTIALGIVSDTTDAGFAWDMAQNYRGYWFDSASSTFTEAGGVNVGGSEESSTSPVEGSAWLQWGGAWGDEQYATSRSGQYCIFGECHYTSGPTGPVAKNLGRTALCQDESDCTVFTSVNDLTHQSKRNERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKD3</accession>
    <name>A0ABR3ZKD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_002216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="638"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="83822" checksum="7AA0CB32976861EE" modified="2025-10-08" version="1">MADPSLASNNPFRRKSTVPIASSTPSSSSAASGLTLDTTSTAGPAHPSLAKSSTFPQSPSDAPFTTHARAPGASGPTGNSGSAGDTYAYDYEDQDALRGRPQVSSDAFREHLQALPKSTEAPPSTTFLKPKPVKKVRVQSPPPSSPSSVDSVDADFEARFPSNLADPTGAPTGAPPATGFGDYGARGGLLDDRPVRNYDDYSSASDDSESDNDSAGRGGSTGPTAAISSFSSVPSQVAQQPPPNPFQKTLGDLEPGQASAEEPQPDPSAATSAGKATLDVDAFSRLLLTGQGPAAAPPPPPPARTEAIPQAQETPRTSRDIPENDDDRSGLIPGAPPASEPAPRQTLKKKPPPPSSRHGKLIKAQSKEKAPMKEASGGGEDPSSFSSDVNKPLPPPPARRSANASEDEDAMDSIFDREAAGKLPEPEVNLDPEAPEEAVPSPRPPTPPNASHSTDFDPSHPISDLGAEALVSSSAAPVAAATATTSSPHPKKPTPAPPPRRQAGHSRTESRSQPQGERPPLPAPPGDGSVSDQQRDKSPIGSPRSSLDSTRTRSRSSSLIKPNASANANSGANVPAPPPPRRANHASRPSTASFAAPLHPSVSSPALSPSALSDNDRSPGVAGLHPGVSTPTLVPQAGSTSGSGSSTPVPNRLLAKPPPPPARNTSVRHKERPAALASADSSGSLGSGAGSGSGRPSSVASFDAVARRVGPHHQPPPPPPTRQRGSSRGSMDAPASHANATTNSSLLSAPPSISSTPRKVSSESVRRAAGNSGQGLETAQEGDEDQANNAGVDDSGVANNILADLDALRREVDALRGQFKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKF9</accession>
    <name>A0ABR3ZKF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein transport protein SEC31</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein transport protein sec31</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SEC31_1</name>
        <name evidence="19" type="ORF">Sste5346_001940</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">COPII-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SEC31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009917">
        <property type="entry name" value="SRA1/Sec31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07304">
        <property type="entry name" value="SRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="7 15" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="164"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="254"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="18">
        <location>
            <begin position="564"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="SRA1/Sec31" evidence="17">
        <location>
            <begin position="1135"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="472"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="821"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="868"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="979"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1019"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1056"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1114"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1126"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1140"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF07304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1900879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1271" mass="134998" checksum="F5A1FB98C41D5B9F" modified="2025-10-08" version="1">MVHLREIPRTAVFAWSPGTGKPFLVTGTRAGAVDADFSDETKLEIWDLSLDSPSHGVELQPIHSISTDSRFYDIAWGPPDADHPRGIIAGALENGSLDLWDAEKLAAGVSDAHIERATKHSGAIKAVQFNPLKPQILATAGAKGELFIYNVEDIQNPFRLGNAAASRVDDIECLAWNKKVSHILATGSSGGLVTVWDVKTKKASLTLNNNRKAVSSIAWDPTNSTKLITASPDDNTPVIYLWNLRNSNAPEKTLTGHEQGVLSVSWCTQDPSIMVSCGKDNRTLVWNPNTGDMFGELQEGTNWAFQTRFNPENPNLTATAAFDGKIAVQTLQTTNNSADAQVAAQSNLDAEDFFATAHTAPSVVNFSLPTPPNWYLKPVGVAFGFGGKVVYFTQNDTPAGQPQSSTIHIEKFSPDSGVAPATEKFETALQSGDVKSICESHVEAAKTEEEKADWEVLETLVDENPRQKVIERLGFSQDDAETNGATEGDESKEKAAEDSEKETSKDAASEKKIDNRLSNFFEDGGDAGGDDDFLSGLSAEKDAKSSQPFHLLGQGNTALEDTITKAVMLGNFSRAVDICLKENRIADAFVIANCGGKDLVQKVQTAYLADANGSPSYLRLLGSVISEDLWDVVHNADLANWKEALATLCTFAKPTEFPNFCEGLGDRVLEAGSRKDASFCYLVGSKLEKVVGIWITELEEAEQAGVKDSTEDSSFAVHAKSLQQFIEKVTVFRHVTKFNDSEASFTSGWKLASLYDKYIEYADIVASTGLMNVAQKYLDLVPTTYESAELSRSRVKLATQKPAAAQRNTAGQSRAATRTPLVNAGYPMPQPLAQQVQGNPTPPNPYGAPAPLTSSTPYAPAGIPQPNPYSSATPPSYGNQTYAPPQQTSTYAPPLGAYGAPSSNPYGAPPRNATPTSLPPPPKAKDVGSWNDVPMITKAPVRKNTPSVAPITQPFGAQSLSGPPPPVSPYGAGPRVGSTPPPPPKGPAPPRVSSPLVGPPPSSFKAPPRPPSSVANAYAPPPPAAGSAPPPMSRPPPRTDSPYNAPPAAAPPPSRYAPAPSAQQNAPAGLPQNGSSIGPPPGAARTPSGQYAPPPPAGNQYAPPSFDAGHGAGGPPPVGPPPAAGGPPRASPSANAAAATPPPPPQASAPPPKKVKHPAGDRSHIPPKAQKLVQVLDFDLQRVAARAPETFKPQVNDTRKRLNLLFDHLNNAELVKDDTIQQLHELSVALENKAYDAAQKLQVDIHREKPEECGNWMVGVKRLIAMSKATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLQ7</accession>
    <name>A0ABR3ZLQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="474" mass="50579" checksum="54D00BF057DAECA3" modified="2025-10-08" version="1">MDPADKFVTPRPPPATPSVVGPLPPPPASAMAIPYERRPLASSCGNKRPVSPLPTPRHLLRHQRSVRSLSPSPSISTWSPRRLFARRASPSREVKLVDGQNEEENTFMPSSVASENDTYLHRPVLSSRLVSSSASSISSISRSRQGGLAPAPYYPSTASQGSRSRDISPESLRRFLVDDAPLESLSSDNISLTGRSVSSTLPAVAVHTDVIGQNSSFLLSETDDEDEDDFDVININKNNRGHDLDFIDDDEHNFATSTTSETAPMTILSPPPPASRNITPLMVPVEEKVDVVEVEEASPAEPELPLPKAPTRAPPAIPEPTLEVAAEAEAEIEAHLDGTVKIDLPQLNLELPPVLAPPSPMSLSPMSMSSMSGALSFQSHEDDSEPLDVDAGSSAALFLPPPEHPFRGGASESCKADPESQQHRQNHHHHLMDAALTGSTTTLVPGNGLIGAGTSSGLDDLVDELGWMATAIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMI6</accession>
    <name>A0ABR3ZMI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dilute domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_001884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15473">
        <property type="entry name" value="Myo5p-like_CBD_DIL_ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037986">
        <property type="entry name" value="Myo5p-like_CBD_DIL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052072">
        <property type="entry name" value="Vascular_dev_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027:SF6">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN YPR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="3">
        <location>
            <begin position="404"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="777"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="878"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="898" mass="99851" checksum="BA847EB71F877117" modified="2025-10-08" version="1">MDADDVENDAFGGGGFASSGDEDIDNGGKKPRALPLDLPKSLDDRRRPTDLVPETELYDGWQGSSQFLTSPMLAKPLGFGELTLNDPNYSEDLTKGPVTDSDTRLMEMLAAQAALSSNAAAMAEDEDTVASNEELSDDEKRATLQRVFNMAASNGNVAQVRKILEGKARPYIDLNVPDEDGTPPLIYASCFGHEGVVEALIAAGADVDRQDRNHWSALMWAMTNRHKNIAKLLLDSGAATDTKTSSGRTAFDFVPPDSEMSFYLHDSGYNIGSAGVTDDFYNPGFSQDRFEEEMAENEMRRRMMMESARDLEVDLGNVGIDDQPEQPVDEFEEEQQEFDWSRCLHDQMFVFQEADLDRILDIVITNMQPQRSPTQKPVPANVIFLSARYAHYHASQDLLAKLLITAMDKINDVVEQHQWDMTILAFWISNATLLLHYLKKDAGLVEATTEFQAQLAELINEIFILIVRDAERRLDKVLDAAMLDHEIIPGFEDITFQNEWKIFKRKKEVKEEPLERRMRPPSPKQRAKPAPRNVTSLLSSTLFVLDLYDVHSVITAQIISQLLYWLSAELFNRIMSNRKYLARTKAMQIRMNVSILEDWARTNNRMPEHYEHGEMRSSGEPTMEAARRHLEPVIQLLQWLQCFSSLGADDLEALVGTLQQLKSLSPQQLIHAAEHYRPEVGEKGLTKSAMKYLVAIQREAQLRRENRRKTMSPTPPVKNTSKKLSKPAAAPAPQAPAFVVKAVASAAATAYGAPPALADFAGSAAVKLNEAQAAEAAAQAAKDAPSTPAKNKNGGGGSLTPTTTPGKNLLDDGDEDEEDDAPKHLLLDPALMLPFTLPSATDMLVSYGAGFGGMNREREHKYIPTLPPEFLAKLETSNANNGNRRPMFGEKDWENEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMS6</accession>
    <name>A0ABR3ZMS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MAP kinase kinase (MEK)</fullName>
            <ecNumber evidence="10">2.7.12.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">STE7</name>
        <name evidence="10" type="ORF">Sste5346_001696</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="10"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06620">
        <property type="entry name" value="PKc_Byr1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049613">
        <property type="entry name" value="Byr1-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="60"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="346"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="471"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="484"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="557"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="609" mass="66769" checksum="B7D2262178E616D1" modified="2025-10-08" version="1">MTDFAPRSMKRKNVKGLALTPAAPKPPPTAETANIGGNDDESAHLEIGIEYNLDLRPADIEFIKELGSGNGGTVSKVRHIPTNTTIARKVIHVEAKREMRKRIVRELQIMRGCHSEYIVTFYGSFLNDNNDVIMCMEYMDVGSLDRVSRVFGPVRVDVLGKIAEATLGGLTYLYVKHHIMHRDIKPSNILLNSRGNIKLCDFGVSGELINSIADTFVGTSTYMAPERIQGERYTVKSDVWSFGLSIMELAIGKFPFAASEQLSDAESAPAGILDLLQQIVHEPAPRLPKSEAFPSILEDMIQKCLYKNPDERPTPQELFDRDPFVQAAKRTPVDLREWAVGMMERDNRKSHLAPQLSPATQELLRGTDSPTTYHGDDRDRTLQTPTSGEIPIVGDILSPRDQHGISLPNRSPTRPAVGSGNGPDSAGISSSGAGSSSSAGFGSLGRASGQAIHPGLGARVATSDSIPRVPVPISTGLGNGLPGGPASAGASSTTFSLPVRLAPHPSGPPPPPPPKKETPDELRRRQLQQQQQQQQQQQQQQQQHQPHSHHSHHSQHSQHSQHSQHSHQQSQQYHHQIQQQHQSQQPPYQQQTVYTSTTSDTYPLGYPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMT6</accession>
    <name>A0ABR3ZMT6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfite reductase [NADPH] flavoprotein component</fullName>
            <ecNumber evidence="7">1.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MET10</name>
        <name evidence="7" type="ORF">Sste5346_001934</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="7"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06207">
        <property type="entry name" value="CyPoR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF109">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="685"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1072" mass="116446" checksum="EED5018216D1C512" modified="2025-10-08" version="1">MQLKHEETTGSPALPVDQPTEELKRLPTTTAALSSINGPTYATAQLLVQQVAYKLSDKIFAYSPETFDLDVAARHWEAQQEKNVHGYPTTVVPLQTRAGAGAFALGYLFSEDFDKSKRNFPQTLVAPTASLRSLRASLDQLSLLYGVASPFVAHVAALDYAAQDGLVGDYSAALQTAEELGLGLVASTSAAEAQHIALFATLAAQILPTLHVYDGLRTARETVRVTDALSEAHIAEAFSRLSALRDERGALSKRLDHAGQLLELLQAFNNELGTAYQPFEYHGHDEAESVIVAFGSIEAQLAAQTVARLAVQGHKVGAVNVRVYRPFIEEAFLSVLPPTVRRIAVLGQVQNEVAVNEASVQSALFADVLATVAFASKWTETPAIVDVKYAAADVPTPAFITSVLQTLTGKPEAEESQFTVSLVPEQVQQYTFYDVDTSAALGAPAAIARVIAEQPGANVSTHNVHDNLIQGGVVRTDIRKAAGKATSAPFAVEAADVTVVAEEKLLKDIDIVAGAKAGSALIVRLPNFKAEDAEKRIPTNVRQSLQQKQVRLYALDTAAVPAVEENSKVLLEQAFLHVAHPELNADDLVRLAAAVNDVDAARACAEVLSQVLLAVEVPATWAEVPADFVAPVALVKTLKPSSFAVFDKTEVEPVTEVSDWQAAAKGLAFKEVYGTQTAVRPDLPVRTSVVTVQENRRLTPLEYERNIFHIEFDLGDSGVTYQIGEALGVHADNDTALVEEFITFYGLDADALVQVPSREDAAVFETRTIYQALVQNVDILGKPPKRFYEALAEFATDDAQKAKLTALGGKEGAEEFKKYSEVDTVSYVDVLQEFQSAHPSIQDLVKIVAPSKRREYSIASAQAVTPNSVALMIVVVDWVDSRGRKRYGNASRYLSLLPVGAQVTVSVKPSVMKLPTLSTTPLIMAGLGTGLAPFRAFVQYRAMQKARGEEIGSILLFMGSRHQREEYLYGEEWEAYVDAGVVTLLGAAFSRDQPEKIYIQDRMRQSMDAVIKAYIHEEGSFFLCGPTWPVPDLTDVLMESIAKEAKASGRKVDPHKEIDRLKEDGRYVLEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP15</accession>
    <name>A0ABR3ZP15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3 10">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MET22</name>
        <name evidence="11" type="ORF">Sste5346_001622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="361" mass="38260" checksum="1BACFD61114B8897" modified="2025-10-08" version="1">MASPAYVKELQVAQLAVQRAAILTKRVFHEKAKGTVSKDDKSPVTIGDFGAQALIISALRHHFPTDEIVAEEEADQLRSDANLRDTIWGFVQNAKLDDAAAEEALGGPIPNVDAMLDLLDQGKSNGGAKGRIWTIDPIDGTKGFLRGGQYAVCVGLIVDGDVKVGVLGCPNLPTDDAVKLTADVGANQTDEGSNVGVLFSAVKDDGAYSRPLTTGNVAPSREIRMNALSSTNGLAEASFCESVEAGHSNQTESAEIARMLGITKPSVRMDSQAKYGSIARGAGDIYLRLPVSATYQEKIWDHAAGDLIVREAGGEVTDTLGRRLDFSRGRTLAENKGVVAAPKNIHENVLTVVQTVLKVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQJ9</accession>
    <name>A0ABR3ZQJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="1">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ASN1</name>
        <name evidence="12" type="ORF">Sste5346_000890</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="588" mass="66460" checksum="DE82AA3E5BF69C93" modified="2025-10-08" version="1">MCGIFACHRHPDVQKFKPTALRLSKAIRHRGPDWSGSVICNQTILCHERLSIVGVESGAQPLTNADESIILAVNGEIYNHRLLRKNLKTPYHFKTTSDCEVIIPLYLEHGLDAPKYLDGMFSFVLYDKKLDRTIAARDPIGITTFYQGWSSKEEGTTYFGSELKCLHPVCDKIESFPPGHVYDSQTNERTRYFQPTWWDPKRVPDTPLDLTLIRETLERSVRKRLMAEVPYGVLLSGGLDSSLVASIAQRETLRMRELAQANGGAEPASFGAPSADNHDNMDRGEGLVGIDDDNKLSTVTYLPQLNSFSIGLPGSPDNKAALEVAKFLGTKHHVMTFTIEDGLNALSDVIYHLETYDVTTIRASTPMYLLSRKIKAMGIKMVLSGEGSDEIFGGYLYFHAAPDREAFHDETVRRVKNLHLADCLRANKSTSAWGLEARVPFLDKQFLEATMNIEPKEKMITKERIEKYILRKAFDTSDDPSAEPYLPDNILWRQKEQFSDGVGYGWIDALKDNAELQVTDEMMKNPKPEWGDDIPDTKEAYWYRLMFDEHFPQSCASTVMRWTPTWSKQTDPSGRAIATHNAKYDEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQY0</accession>
    <name>A0ABR3ZQY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ndufa6 NADH-ubiquinone oxidoreductase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NdufA6</name>
        <name evidence="9" type="ORF">Sste5346_001019</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016488">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="108" mass="12762" checksum="ABF96886EDD6DB9B" modified="2025-10-08" version="1">MAILPTEFARVTRQSANWEAPEIQTMYSVPLPVSAVRTRMRQEFERHRFVNKLPVVDVLLFQSNADYQETMNFWRQTTHIMSYFKEESFKQGPKIPSSFIEGFLEGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZR64</accession>
    <name>A0ABR3ZR64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">O-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_001690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050362">
        <property type="entry name" value="Cation-dep_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509:SF14">
        <property type="entry name" value="CAFFEOYL-COA O-METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509">
        <property type="entry name" value="O-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="27229" checksum="2B8E1B8E20B12939" modified="2025-10-08" version="1">MKANVPSLFPNVKVATRVIEYAAAKSSVLPEPLLKYHAQILELEHANLTISTYQAQALSFLAQLSGARRVLEVGVFRGFSSMVWSHAVGPSGKVTGLEFSPEYAEAARKGFAQVGVENAEVIVGDAIETLDALDPEEPYDLIFIDAQKSGYPTYLQTILKKSQPGAARRLLRPGGLIVADNVLRRGLVADDSDDNPEAAKEAALIAEGGSYRTVKDMDALREFNTALAEDKRIDTWLVPLYDGIGLGRLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRG9</accession>
    <name>A0ABR3ZRG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046591">
        <property type="entry name" value="DUF6649"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20354">
        <property type="entry name" value="DUF6649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="310" mass="33345" checksum="C653AA8C240E961E" modified="2025-10-08" version="1">MLHPNSASTNGANGANNTNGLAPADPGLTRHSKRKATETPEGNERLSKRLSLLNLESSGTKLYVPVESSSSRESQAVQAPPTVALQDAPIMPPTIPEESAQSDISMSPVTSAPPSPPLIPTSTPTSRSPLSTVRNFDGAGPDDDMRVDDTKYKVYIYNIDDELADDERSVSDTDTPAGEDDVDGSGKLVLLPDIDKHLRQAARTAALTSSSTKQKLAIPRPILPNKDGELAGMQLVLYNDPSSLSVPRESDNVRKAILDARARIRERQQEDQKEQAREQQPELDASMSSTPADTPRPVEGDNDSDAMDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRP0</accession>
    <name>A0ABR3ZRP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="335" mass="37216" checksum="5D0217E308B567C7" modified="2025-10-08" version="1">MSAMPSPYHEMTSSYPTPVPTPASGFHDDGAVGHSRHNGVIQATVGRESPSSFLFPADSIAAIKSAQWQRRHDTHKQHDDSGDYKISYSYPEALEYESSVQRKSSEYAWGYTHAHPETMDLDSHHDHRRVMTESPVSAHDDRTSHAAYNYRPLRSLAHSPSAFSDYNTECHQTAKPFYGVSHQYQEHDFKQRIWETSEATTPVTSAAAFETRRYTSMPSPAHSQGHPSSPRATKTMEEQLSVPRTLPLSPASVPEIMVQPSLQRSSSEMQSQDHGSAYNPDALPATMDFTRTYNPAYTTRNSTIEAHPSPRESVASPAAISTPCHASMYPGSHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRV0</accession>
    <name>A0ABR3ZRV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1903155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="399" mass="43901" checksum="C9524EBBC92AEB1D" modified="2025-10-08" version="1">MTDSALFSPVRVGRLDLAHRVVMAPMTRRRATIDYVPTPLMTEYYAQRASVPGTLLISEATSVSPRSAALPNTPGLFNQEQIDAWKPVTKAVHDAGSFVYVQLWMCGRATRPGAVKRGAAVLSASDVPVGPDSPVPRPLAEDEIQTCIKDYRQAAINAIEAGFDGVELHGANGYLLDQFTQDVSNKRTDEWGGSVEKRSRFGVAVATAVADAIGADRVGYRVSPWSRHHGMRMEDPVPQFTDLVTRLKPLGLAYLHVIEGRVQANADLPAHIVAEPVDFVVDIWGTTSPVIFAGGYNAQTARERVDSEQKKVEGGKTREALVAFGRTFVSNPDLPRRVQEWLPVVRYNRDLFYEVESPNGYTDYPLYVEEKGDGEKKDVVRTSKDHEWPAATVGVLVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRZ4</accession>
    <name>A0ABR3ZRZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_000950</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1903037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF83">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="63"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1903037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="551" mass="60297" checksum="64C134CAC8FC605E" modified="2025-10-08" version="1">MALALEKPDAEPGHVENGFGSENTPQAIADAKLVTADAVEAARDEHAMLFWEAVRSHKKAIFWSMLVSTSIIMEGYDIVLVTSLFAQPAFAERYGSYTEESGWQLSGPWQSALGAAATIGAIIGAAANGSLTYRFGYIRVLLGSLASMLAFVFLLFFAPSPAVLVVGLILCGMPWGVFATSAPAYASEVCPLALRGYLTVYVNLCWAIGQLIAAGVLEAFVDRTDQWAYRIPFAIQWAWPLPLLASLWFAPESPWWLVGRGRLREAEETVLRLSSSKSTPHEHAQEFARRQVALLKHTIDLEVAEETGTSYWDCFRGTDLRRTEIVCVAWAAQVWCGSSLGGTPVYFFVQAGVSTSNSFKFSCGGLGLACLGTILSWGLLSRVGRRTLYVWGLGVLFMCMLIVGVVSAAAGQGSASSYAQAGLVLAWMFLYYITVGPVCYAIVAETSATRLRSKSVALARIAYYISQIIGNVIEPEMVNPNEGDWHGKAGFFWAGTCFVLFLWAVFRLPETKDRTYAELDILFANKVAARRFSKVDVNPYAEEGEQIKDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS22</accession>
    <name>A0ABR3ZS22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_000863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="328" mass="36165" checksum="91E93DFDCBD2554A" modified="2025-10-08" version="1">MIDGLYSSQGSQTSLVRGVDPKLFNRDENSAGRNGRVPFRPPRRAQSTNDYVYPSPPPLMRGESRTVLIHQNSSNNIPQAPPTASAEATLSGDAGKTLAAHGRPPTIDEETASGLASPNAISPVPTPEPTEGGRQTRPKLGPPRRSYSVMDYEPVPHHHRLSENLGLLDLPSELHFTIFDFLDPIDSTCLGLTNRHFYDIHRRMHGSVPLSVRRSGPNDMEWVWHLAGRMMHGGHSDAATLAATTNALAMLRVRGQALCRKCGVSRCELHKHIQGWMGPGYEYCTVREKFGPPAPEGAKEFCYLSNPKDPHRCGRHRVNKSRPTTPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSE8</accession>
    <name>A0ABR3ZSE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">25S rRNA (Uridine(2843)-N(3))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021463">
        <property type="entry name" value="Methyltransf_34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11312">
        <property type="entry name" value="Methyltransf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="43193" checksum="DA3300117E21C4A2" modified="2025-10-08" version="1">MPRLRGTNSAGSSKNSKLAAHKPPTLKPGSKALAASAATRDATKKPPAGYQQKILSHNLQQGLLDVFRRALAPALASPRLNEALQAVKQALFERDFAGAFGTVDDAETKKDEPTKDEALETTDDNIKAEKSVSFAIDSEAEAIPPLDAYAARWSPTRALCYASILASPVVQEHWNTTTDTEAETKPALRMVAIGGGAAEIVAFGAMLTNGEAGAAQPGDLILVDSGPWASVVDRLRNSMVEVRSEGRVLALVEPADRFSVDVRQRDILKVDDEEMGKMIGGSGDGALTTLVTLFFTLNELFTAGGLGSAATFLLRLTAAAPSGTVLLVVDSPGSYSEMTVGSQARKYPMRWLLDKFLLQDAEAWTKVHEDEAIWYRLSASLSYPIRLEDMRYQVHLYVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSR0</accession>
    <name>A0ABR3ZSR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pre-mRNA-processing factor 39</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PRP39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059164">
        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF5">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1903322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="68380" checksum="98169DA2B599FC75" modified="2025-10-08" version="1">MSDVTMTDYNYGGTDEENAEIRTLSLQLDADSDNFELWEKLLYACEALDGGLNRNSTPQAIETMRNTYDRMLRKFPLLFGYWKKFADFEFNISGPEAAEMIYERGCASITNSVDLWTQFCTFKLETTHEPQPVRELFDRAADNVGLDFLAHPLWDKYLEYEERLEATENIFAILKRIIHIPMHQYARYYERFRQLAQTRPVVELASEEVLTRLRAELEAEDPHYSSKTEPEIEAALRAKADALSYETFTKTQEETTKRWAFESEIKRPYFHVTMLDHAQLINWRKYLDFEEASGDYVRTVFLYERCLVTCAYYDEFWLRYARWMSAQPGKGEDTRIVFLRAATLFVPISRPAIRLQFAYFEESCGRIDTARAIHEAILDVLPNSVETIVSLANLERRQVGLEAAIDVFKKKLGEPEVDLFVKAVLVAEWAFMLWKIKGSVDDARTVFVKNVEYYADSRQFWWKWFNFELAQPTTAETEAQAAERVDNVITEMRTRSQLSQSTKKEICEAYLTYLQQRGGKDSMKKFIEIDREIFGPTSVQTSTTKGKEASEPPASLDEATLQKAEARYQSFYEVYASPDPLAQGPASFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZT12</accession>
    <name>A0ABR3ZT12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FKH2</name>
        <name evidence="10" type="ORF">Sste5346_000188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="118"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="337"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="337"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="250"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="427"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="627"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="480"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="683"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1903560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="738" mass="79989" checksum="1281A5F98875B0FE" modified="2025-10-08" version="1">MPTPRRSSQRRRKDSVTDRPEESSPTRPAKRRKQADESPHDVPEEETSSLLADSSAVNPADETQIVARVTQHLLAPNDDLRASKDHSNAIHEANKEGVQAYAKIAAQDWTFYVTKLTINIGRTPEPPPEYPPRYDPDADPDFVHIDLGPSKMVSRQHAQIVFNTKSEKWFLNVKGRNGIKVNCAPWRLGQSKPLESGDVIDVGGIEMMFVLPLETSPLHIHDVYLQRAGLPKAEPGLSDDTPLRHKLRATTPVGAGLESSPRGGSTIRSTLPRGQPTPQVIAPAPPDYKRPGTPPSARSRTSISGSNLKSPQFRDIPTMVVHPNDVDLSLDENKNMKPQYSYAQMITQAIMNTSEGRLNLNGIYTFIMENYSYYKHQQAAGWQNSIRHNLSLNKAFEKVARSTEEPGKGMKWYILPEYKDEMVRTAYRGGRGGHRGSSNPSSPSQLNYVNQGPRDMAAKDTGSARKRRVSPTGSPQPRSSLRDMHMTPDRSSRRLLPDEAPASSDGSPLPRYRRGAAASKAKNSTSILGGAATNDASASGTAPDPVIPRSPTLTSTFLQDDISSSFVTPAPHRVELKLNPPSTLQRPSQHMPTSSPAPFWKYADIGSTPLKPPASFDFSPSKALGLSSGMSSSAAMAASSSPPPVKRSGIKSPISSPTRPARTISETKDEVPASDATEVPPTVETPPAPAPAPAPAPIIPEVEEDGGFDLSKGFQSIGSYHAPVRHGLPVATAMNGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZV14</accession>
    <name>A0ABR3ZV14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rho-GTPase-activating protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rga8</name>
        <name evidence="7" type="ORF">Sste5346_000423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04436">
        <property type="entry name" value="DEP_fRgd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04399">
        <property type="entry name" value="RhoGAP_fRGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF17">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN RGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="6">
        <location>
            <begin position="2"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="DEP" evidence="4">
        <location>
            <begin position="211"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="468"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="678"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="695"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="717"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="798"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="851"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1903139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="893" mass="99014" checksum="903C4945209C9955" modified="2025-10-08" version="1">MPGFADSFWSSDYAAGLGILFGKLQQGVIENRQLLIVSRMRAEAEEVYGQKLGEIPLSVDKVQGGFSRDDGASVRKAYEGVRTEMEDAARNHRKIAQNIRDLVVNPFSRWCDAHEARIQDCQDELQARIKTHDRQLENVKKLRNNYFNKSRLLEDLEEENKLAFQDPETSPKNNIPEIKVEKEEEPEEEEPYEIGDETYPPEQVKKILSHMLNNIKMGETKVPILGTYQNTSAGSDIVEYLQKNMNTSSVSYAERIGQDLVTHGFLRLVGNVGSTFANSSKMFYQWRPKAFQMSGVPEKKVPLGRTFSLTAAGTDPNSIDSPVIGTVNEYLEKWNVLGTAYPNETPSDRMRREAREADERYKAGVRRLDELRCELEEAIFDHLRFLERCELDRLKAIKTVILDFSGTISNVIPSLQSTVDKLVLYQETVQPLGDLRYLLENYRTGSFIPKVVTYENYYNRVDEETFGVDLEARARADKKRVPIVVTTLLTYLDHHYPDLEGDEARRNVWLIEVPLYQVHKLRAKVNHGKTFSPEILQDFDIPTIASLLKLYLRELPDSLVSSHVYEIIRTIYQTPAGETPDDARRVPVLQQTLSQLRLTNIATLDACMNHFTRLIELTSADETYVAALATTIAPCVLRPRVESSLTMEEKHAYRLVRDLFAHKDAIFSELKRLSALTHSSSVSRPSGNLAAANAPGGGGGPGNGGIGNRPRAISTDESNRKAHMEERTRALLEKANGGRSRATSPAPSPRASTHRRDRSIGGPETRFPIQTSPTASTERHRQSIGPILGVKRSSLEVPGDGAAAAGTTDPSATAANGAPGLEASALPADGTSPGSPADKRGSMNRSSVRFVGGRRIAPVAAGGAPASGSGSVDESGNRRHSQHAVTLVDRPMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFK3</accession>
    <name>A0ABR3YFK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000150">
        <property type="protein sequence ID" value="KAL1887079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="456" mass="49238" checksum="CDAF7DF863EEC4D2" modified="2025-10-08" version="1">MGRPKSRAGSKAVQDSVTVATDPTPSPPTTRQKAAAGATAAESPKKTRKQGRSKNKPLEDDSDDNADDRKPSTPSPKKARKAPGKVTATSPTTTREAKKAASKTKKELDKSLRKAKRAVDDMVDSFDASSGYPLPGVLSPSVEHKGEVLRDIVALAIISSLLSSGARFTMEWLADSFEQTWMSGVLFFGTAGPLDIVPFAASVLARTVRLAVSWGSSGSLSALQALSSTPIIYLLHSFYNVPITASFFAEILTINVETYVLEGYHFFKGTSDDDTEDDKERDDFFNLMKRDIITVVYPYTFAAVIYVFILVQACRFFLPEAFVVHFSGIKTVEPARVPSLLSASIPSVSDLFANIFLSFSAVVVSSLCGLFCRNYIFGFTKDAPRRNNTGFSRSAHIRRQTIDARTLACALSVGLSVYTQCLYEIPGVDNVGAAAFAAIWSAAPLAVSMGLIFTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFR1</accession>
    <name>A0ABR3YFR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_010420</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000144">
        <property type="protein sequence ID" value="KAL1887131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="792" mass="85520" checksum="B41E73E04D6C16C6" modified="2025-10-08" version="1">MTTISTTDSTATTKRHRQGRSTKQLACTNCRRKKVKCHPGPNGPGTTCDLCHRLQEVCWTPPFDERRRVHTKQLIAQLRSDNAELQAENAQLRAELEDHRRLCRVDGNGGCDHNFQSGSFSSGMSDGSSEVSTSDEAPDEAAEQTTTQRTATAAFTTLASSSSSSVFRRSDNMIMRLCSGQRQLNSDRVGRLRFFGPTSSLHLVESVTSSLLICGSSRGGRDGSNGRRGGGSGGSSGVAIPTWQTDFPPQVQEHLLDLYWTYQHQVLPWYVTAFLRDMRNGDTKYCSSLLVMCILTRAAAISSEPALRALALADDAEAAEDDPPYLVRKCVVMLEHELDAPGITTAQALQLLSEMHCAISHDTKGWMYAGGAGRLAYELGLHRDPDDFDSSGFGTTSTSVAADMTQLDKEVRQVVFWSCFNLDRAWALYLGRPQSIRLEDVDAKRPGEGGAADTEPTGEVRMAAAWCSLLEIVGKICEILNGVHTPRWRLGKEKPNLHVQHLHLVQRLEQWRATLHPSLQYETSQTPAMIILRMQYAAAMILLHRPLAQFGTDLTALPSPAAADAAQSRQICIEDAGRIARCLQEYADGHGSVMTMSWVSLHIVATAATTLIASIAEHRPPGTMSDSDMAAVAPQLDSLRRCLTTLNELEKSHVVARRVRKVIQSTIRLLNMDAVIKTGPGNSSGGGKSSVGISGIGGIGGGMIGNWPMPFAVDSITGFGMGTMTGVGLPWTTSTSSSLAFLSNMGMGGIPATAGLGQHSDGNTAGSFPLGNFLPSSNAPVEFLNSFETCFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG26</accession>
    <name>A0ABR3YG26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000137">
        <property type="protein sequence ID" value="KAL1887192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="173"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="332" mass="36899" checksum="D5BC3FF763E53E71" modified="2025-10-08" version="1">MANRADKVHLERLSYVIYEHPDPNAFLLFADDFGFELAGSSMKDNSEFFLRGYGVDPYLYIGRQAPSGEGKRFIGAGFRARTSEDFDKATKLDGAQVTDLSGMRPGAGKLVTLKDVNGYDMQIVFDQEERPHPARGVSNVTGGNPNSNGAVAKDRLGEGVFNRMGSGPAKIHKLGHFGYMTDNYKGTCDWYTSRFNFVASDVVVKPGEPDHELMSFFHVDLGKEYSDHHCFLVAGHHGSGKGTSVHHSSFEVEDLDTQMMGHKWLEEKGYKLMWGVGRHIMGSQIFDYWWDPSGFIVEHYADGDVVNEDIPTVRSAGTAAAIWGPPMPTKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG36</accession>
    <name>A0ABR3YG36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Caffeine-induced death protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIX23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000148">
        <property type="protein sequence ID" value="KAL1887099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019171">
        <property type="entry name" value="MIX23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31905">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31905:SF2">
        <property type="entry name" value="PROTEIN MIX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09774">
        <property type="entry name" value="MIX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="23572" checksum="A1B0337D990BC51A" modified="2025-10-08" version="1">MATQPNQPALTPQFCFSTVVLRDFLRASRAIDDTITQHLNALVTPSRAGFDPSSTAHRASSYSSGSSSSSSPPAAACRAFRDALLFPAWQARDDVIRYCAGVADDAVAKDAEEAAQAAAQAAAAAAASGALVEGDFPPPTQPEITERFDPYIKRKQYALAEPQANLLASLMRNEKGVESIVRARSWDVLQARCGSGAVTAGTSETGWEAALEQWRKRERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH29</accession>
    <name>A0ABR3YH29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Golgi transport complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">COG6_1</name>
        <name evidence="6" type="ORF">Sste5346_010079</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000113">
        <property type="protein sequence ID" value="KAL1887631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19509">
        <property type="entry name" value="RecA-like_VPS4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="660"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="172"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="513"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="513"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="919" mass="98982" checksum="FA3D289B86BC65A0" modified="2025-10-08" version="1">MLQSGTAASSLQKIYEEGYLTCSTAVYYEGQGNEEEAMRCWRTAVQQIQNKQADGSIPEYAALTETEKALSDSLRELEYQAQERIDLLQALKESRRVDPFQDPPGSYPGSSANPSNSYNSYNSGYNGSNGNNGSNGYGRSAGYGSYGEGPSQSSSSPNSGYIGGGTIPAITYSELSRPEVSRAPPPVPPRISASSSRPPAYDSGRGPIDQPVTPGQLDGAGTSSYYSARPSMDSLAATDSHYDAESSQGGRHMLSKRTSRSPNKDRQHTLRPTLRSTPTETPLKSSRTSRLARSSAPKSSVERQGASKAATLAWSALGLSAYGKSDSSRKSSSAPADSSSSKAQIMPSSSLQMPSRKPVRETSPSSQPALQWDSNSRRLVPQRSAPEPANVSPSHSSADLISLSPDTRRSGEYASSSKPQSLSLNAAASALGRSMQAPAEGGRPSRLNRSTSNQRPSLAPAASPSLERVSDPSVRPKSTGHTRFPGSGGTSNHSALGNRIEIRRNVHSSYAANVAASSSSPSLDRTTASAPVPPSSSRKPAPRKDKAPVRQAHEVSHLLADVHLEPSSSEDSDKLDDNDKDSEEDLLKMPWKKRKQAILKSLPPGVDDEAAKQILNEIVVQGDVVHWSDIAGLEPAKKALREVVVYPFLRPDLFMGLREPATGMLLFGPPGTGKTMLARAVATESRSTFFSISASSLTSKYLGESEKLVRALFSLAKMLAPSIIFVDEIDSILSQRSGSGEHEATRRIKTEFLIQWSDLQRAAAGREDKDESTKDSRKGDASRVLVLAATNLPWAIDEAARRRFVRRQYIPLPETETRAVQLRTLLGQQKHSLTEQDIQRLVELTDGFSGSDITALAKDAAMGPLRSLGDALLMTKMDEIRGMELSDFVSSLVTIRPSVSKSGLKEYEDWAREYGERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH75</accession>
    <name>A0ABR3YH75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ERV1</name>
        <name evidence="9" type="ORF">Sste5346_010089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWCUI010000113">
        <property type="protein sequence ID" value="KAL1887641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="87"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="197" mass="21007" checksum="E88D02295C94A061" modified="2025-10-08" version="1">MSAETQQPEQPAAGAEAPKRIPKGVVLGPDGKPCRSCTSFASWANQTKTSLKTPSSSGGSAGTAAVAAMAATTATAAASSTGPPSDCPADVETLGRGTWTLLHTIAAQYPKQPTPTQQADVKGFIGTLSRLYPCWVCAEDFQVFLSKSPVRTASRDDFGRWLCAAHNEVNDKLGKPKFDCNLWEERWRTGWKDGRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHV5</accession>
    <name>A0ABR3YHV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 127 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_010236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000121">
        <property type="protein sequence ID" value="KAL1887413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049174">
        <property type="entry name" value="Beta-AFase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049049">
        <property type="entry name" value="Beta-AFase-like_GH127_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012878">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049046">
        <property type="entry name" value="Beta-AFase-like_GH127_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465:SF2">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07944">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20737">
        <property type="entry name" value="Glyco_hydro127C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20736">
        <property type="entry name" value="Glyco_hydro127M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic" evidence="1">
        <location>
            <begin position="55"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle" evidence="2">
        <location>
            <begin position="436"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 C-terminal" evidence="3">
        <location>
            <begin position="523"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="68136" checksum="3B5A6001D83081DF" modified="2025-10-08" version="1">MTLFPVPIRAVSITSPLWAQVTQSSRERTLPSIIQTQKDLHHWWCLTWPEGHLQKPHAFWDSDIYKITEAACNFLITHPDPKMLAEVEATVDMIRKAQYPDGYISSYFTTHGISKRWTNTRDLHELYCIGHLLEATVAYEELTGTGRLLQVAKRVIDHVATIFGPEKHKLQGYPGHQEIEIGLLRIYELSRYQPAFDLAKYFILERGRVYPDGEIFYDKEAKARGADPYDDMGTEHKAWFHGPRDYAYQQADGPLVEATTTKGHAVRAMYYYAAATDLVRLSSEKDADALAVKAALQRLWRDLVDKKLYVTGGIGNARHNEGFEAPYLLSDLEVQGCYAETCASFGLINWCQRMLRLGLDSEYADVMERALFNSFLGAVSADGNAFYYQNVLRTLEGQPKERNTWFAVACCPPNMAKLLGSLGPLIYSTNEDKSLVAVHLYIGSIIQVPGTNIVIEQQTNMPRDGRVKFRIKGTTRLALRVPSWAQSLAVSAKGEVKNGYLYLSSSTDAEIKVEFGMKPEKIYANPLTGKDEICLVRGPIVYCIEDVDNEGMSVDNLILTDGPVSDGQEIEIGSIKALTLETTGRQIQPAAGEGLYSSRPWLKSPSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT3</accession>
    <name>A0ABR3YIT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_010036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000111">
        <property type="protein sequence ID" value="KAL1887696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="774"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="878"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="983"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="933"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1153"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1345" mass="144124" checksum="01DEDE9993736231" modified="2025-10-08" version="1">MSLNGLDNVAVKEAHEAAVSEPGGWFLLKYASRDEIELLGRGSGGIVEIRNAIAEYEEASPLYGFLRYRRRNVILKYLPENCSRLVQARVTVHFNAVCERLAPYNTTFSIADAKELKDTKLSAACSLHTASSSTSSSTSSLRRRRLMEIAEEEEEEQRATKRQSIVKEEGRPGQDETGSTISASALPPVTLNSQLAKSPDESKFAGTTDPPSFTGVERPSSPAKSLDARRLSSQLTRPEMYSYSSYTYGKPKVKLAPRPSLDTSGRPRTSAGTGTHRPISAIPAGFKLFSKGSRKGRGESKPSGNSTKQIDEEEKADATAQTTTEAASIPIPADPSETLDVKRPHTSGGRPTSSSGISMKSVATTAAAAAVTKQNTITPEKARLMKAMKLREKKKKMSIQPPLPIPTVDISEAPNDDGTAEDTSDSAPATGVSLTGSFEDRPGTSDGLNSGDSYASNANPGDSAIDVGLSAAVDQISIETHTTDSHPASPLAMSSEVGDSTKASSLSESTDETVQALQELKAETDPLSPGDSTTVNNHTTTTEVDESSQKVDDVQCDVLQDEETEPSKANAQPEESPSHDAITTPVVDGGESHDDNKPVATQPEPENDTAAVDAPAEESVEEPVQQPIQEPIQEPVQEPIQEPVQEPVQGSIEEFSPAKDPAQTPAEERTGEPTDSSRPSTSTTSEFTADLEDETLIPSITIPTISAPEPRDSQSTIGLETSETASVDTKRARRRALVDPIRTDLGGSQGTDAARSDANLSDDDELMEELQSATVQEAKPMTVSKSPITPVFPSTSPSKNRAAGDEAFGRVVRTVSSPVRGSLLVPGDPAAGGTSRSVSSSAAFLQKIAQQNASNLAPKKTNLGSSISQRIKALEKLSASTAGPTVEAPARAERPTSTFFSVRRPVTRDTSRSPSVVERATSLTRDKTPSPPTSRESTPEMPRLTSRDRSGSMASRLSVFENGNPPRGRPESVQVRARIIRDPTQPFPKVHDSHYDPTDSSQLQLKQSPLVVDHQRATPLFTSAFTSVSGAESSTESERKKESLLERRMSKEKRRSQSQDRSTIADDSEGTRPRRRSSLSIVKDFIKDRRGSVMTGRLPSTDNLSVNNLASPASLFSPSKSPSRPPSVHTTHGLVRRLSISSRRSTSKDRDMNTPPLNTPLSPSLMTETSGSGDESKSSASELGHKKTGSGGNRASRFMRRLSSSLTTGRKTITPTISPTVAEEEEAFNTIPPSRGGPAAQSNVVSYVGDVNVQFPDNLLWKRRTMCLDSQGFLILSTGNGVTAPVSDRPAGTVKRYHLSDFRVPYIPEMEVQELPNSVCLDFVDGSGLQIACEDRAGQMNVLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJH2</accession>
    <name>A0ABR3YJH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_009865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="43152" checksum="2C36F7CC6C54E8A5" modified="2025-10-08" version="1">MATATAIANRSCISSGTVVLVSGLAMFERSNGRNDHWEIHMQGLKELVQYYGGLESLYTQPGILEKIFRADLYGSLDDDVPPYFDAHDLCIRLAEAVPADIFFYNNADADTDTQTVLRSAGLDRLTPQLDPTLVRCAHQLEEAMVGWDNMGGFEASEVTALEAAASVASAISPAAMPIAANRTTITRRPSVAAAMQMRYLLTGIQYMLVSSVLRQKLASVVKVRDRRLGEMVRIGLMLFSLSILNERPMNATYALKLVAKLKGILEEEALAAATELEASTEISIPVDLQLWTIFMAVSVTNGGTRWPDKIRDDDETSWMLDAFTSRLTSSEYSSSNSNSNAAGADHKVQTHLCQYPWVPCIHDKLFQRMWFVATTSTEARVTELGTAHKEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKF8</accession>
    <name>A0ABR3YKF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000105">
        <property type="protein sequence ID" value="KAL1887914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF22">
        <property type="entry name" value="CAPSULE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="339"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="660" mass="74877" checksum="3D00967B06D4DD16" modified="2025-10-08" version="1">MLLPVLAPRRPSLLVRYIAPACFLLLLCYSFSIPSRLQLAAAATAAQLHEKHRQHYHQGQQVPVIIHGDDKKNGKPSSPQTPTPASPSSTQHPVEHLVAEAERQFRDLLAQETHSLGDAAAAYRKRRGRHPPPGFDRWHKFASERNVVVVESFWDQIYHDLHPFWALPPKLIQREARAFDMTIKIRKGRATTKSSWFWTQIWLDLLRTIESELPDMDLALNAMDEPRVVVAWEAMKNYVVEAERTQVFPPPEQVQQAFQSLPFGDDDNSKDREAVRDDNRWTTTGPFWELVQRGCAPHSMARQTSTSSAARTSKDGRPIIDDTYTSPHMYHGFVSNSSLSSDICHQPDLQGLNGIFIEPLSISTTGTLLPIFGGSKLSVNSDILLPAPMYWSNEERFAGGGGEASDVPWSQKRNGAVWRGVATGGHNRASNWKGFHRHRFVAMNDGQLVSKAEANPDDVPNFTLPSPSYHILAQDEDHLGEWVSQWSDVGFVDLMCDGAEKKVNDTTEGSCPYVDDYFFIHNSISLQEQFHSKFLPDIDGNSFSGRYLAFLKSTSLPIKATVWKEWHDARLVAWKHFVPMDNRFSDWFGIVDYFMADRQGGQDKNGDRVADKIANDGRAWADRVLRREDMQVYVFRLLLEYARVLDEKRELLGWVGDLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKI3</accession>
    <name>A0ABR3YKI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_009623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000094">
        <property type="protein sequence ID" value="KAL1888343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13220">
        <property type="entry name" value="PH-GRAM_GRAMDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="909"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="510"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="782"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="871"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1079"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1226"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="786"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="814"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="871"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1085"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1097"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1226"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1258"/>
            <end position="1277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1305" mass="137593" checksum="96C4A81B15FF3D76" modified="2025-10-08" version="1">MDVSTESSPANSINGGNGSNSIGRGKIPKPKPIRRWRRSAKEPASDDDSSSNTPPQPPPSRGRTTLSQQTTAAEDDGLLDMVDEEDASGRSDDELFPPRPKASLSTHPSQIGYLTTSSPLVQADHLQDIRTPDDDNDPFARTSTLPLETTDSGTLDYTLPISSSKTGLVPPSSKNRRSASPVGRFRSVFKSKKSPAASIASTDSHSPERQRPVDLTKADTVEQSSKSSDSAAPSLRTQSFPSITVADSSSSSTPPSSSHDATEGAQHQPDTSKVTPNERFRRLSRGQKVDTTARPETPPANEKATPVIVNTPPTPTDPSHPNTIVRPRTAVTASPDTINYSPAGHSNGSSPASVNHSMIAQRRSRAGSASLVPSKLSNFTLAPLTPTPESGAVTPSASGFFSSVFSAAQNATNSLSNATNSLGNTIASTNLTAPWSNSSKKTGGKDQDDKTGSSVTVSTVGTDEDHDNEVEVESSLGASLVPSVSSGSKEPAVKTLGMGDLSLSQLGIAEQPKSNNSSASNSANNSGMANSPVLHAQHVSEVSSESRHRSESAPADSSHFHSTSDYADHGSDAGHSGRPGSVSDFAHGDRTPPTASLYGDKEPGAVQRTGSIRSAIGRRRHRGSSAVSGGTIAAAIAAANHSLAHPAHAGSTPKLTGFAVASKKRNRDFHSFFKSVPDDDYLIEDYSCALQREILAHGRLYVSEGHLCFSSNILGWVTTLVMSFDEIVSVEKRSTALVFKNGLMISTLHAKHIFASFASRDSTYDLIVKIWKLGHPSLQSSLNGVRIDETGGDKTEKIDEGDEDASTGSRSDSESEEDSDEDSNDVYDEDAEDDDAHDVTQASDTNGGAADADAERTVTRKVSGAAAVAAANGAGADKPKDAPAAAAGGDFPGPATHAPTDCGNADSHYDKGLIDEVIPAPLGKVFSYIFGSTSVTFMPKWLSNDQKCFDIQMPDKKGLGPDNKSRTFSYIKPLNASIGPRQTKCIVTEQVEALDFEKAIHIVCSTQNPDVPSGNVFTVKTNYCLSWAEGNGTRMQMTCTTEWSGKSWLKVPIEKAANDGQAQYGRDLLAGLKEAVSARPRAGTGSNGGANGGKGGKAGKKGRKGKAGASASGPTSDSERSKPKPSAKSDWGLLEPVHGILGPAVDIVKPLLTGNVMYGLLVGLLVASWFRFGSNGNNGGGAGGVGLRRGVGYPDRLAAYEEMWHREESDLWDWLEERVGLDRMMDGGGVVGGPVGSRAGSSSSRGGGSKSGSSSQKRAVEPRTVEDKLREERMDDREIREAIRVTEEKLQVLKQVVDKREKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKY7</accession>
    <name>A0ABR3YKY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF26">
        <property type="entry name" value="ADP-RIBOSE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="208" mass="23286" checksum="A7BE31C80444B6F0" modified="2025-10-08" version="1">MSAKTQEPEILKTEDLQTSEARWLALKRIHYVDQVGKERTWEVATRKTRGKAGVDAVAMGNVLRHPSRPPATLIVIQYRPPLDAYTVEWPAGLVDADETAEQAAVREFKEETGYECRVTSVSPPQAADPGMSNANMQLVMVDVDLAEDDSVAPEQRLEDGEHIERVIVPLSEFYDRLVEYAARPRYVVAAKLFHFAAGMQFAQTTKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLI4</accession>
    <name>A0ABR3YLI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_009118</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000080">
        <property type="protein sequence ID" value="KAL1889053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="578" mass="63868" checksum="A993CC9CC6AF901B" modified="2025-10-08" version="1">MSVPDGSRFDFIVVGGGTAGNIVASRLAENAKVRVLVIEAGIGTSKDNEEIRTPGLAMDIRGSQYDWAYKTTMVKRDDYERIEKPNTRGKALGGSSSLNYFSWVPGSKGTFDMWEEYGGKEWTWDPLVPYLRKSVTYHDDAGLYSAALKKIGSGGPIPIAHAELIPEMKPFRDLVTQGWKSTGEPVTENIFDGTMRGLVHSVNTIYNGRRSGSFLAVADKPNITILAETNSKKIIIDDADRTAKGVTVIRDGKEFSYFATREVIISEGVFESPKLLMLSGIGPAPELARHNIPLLVDSRHVGQHLLDHPGVPFVLKIKDEYSMDTHVLRKGPLQTSVLSAYAKSHQGPMASPFLELIGFPRIDSYLEKSPEYRARKAANGGKDPFCPYGQPHFELDFLPLYGSAFQWHFPLPTKGSHMTVMVDLVRPVSEGGTVTLNSADPLEQANINLNYFADDLDIIAIREGIRFAYDVLKYGDGFKDIVVDEYPWDMPLDDDEAMKRTVLDRSQTSFHPCGTARLSKNISQGVVDPGLKVHGIKGLRVIDASVIPVIPDCRIQNSVYMVAEKGADAIKRDHADLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLS0</accession>
    <name>A0ABR3YLS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_009347</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000085">
        <property type="protein sequence ID" value="KAL1888793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052174">
        <property type="entry name" value="Flavoredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43567:SF1">
        <property type="entry name" value="FLAVOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43567">
        <property type="entry name" value="FLAVOREDOXIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="5">
        <location>
            <begin position="75"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="258" mass="28464" checksum="539787A4951B765E" modified="2025-10-08" version="1">MPRKRKTRSSGEVELLPAEYGPAQSPVATEKRQQSEKEKSPGDAETSPGAEDKEFQGSPTADRPFTSLPLRQVCRLIEPGPILLVSTGAVADGSHNLMTLGFHMMLQHSGPTLVGVCLGPWDASYETLRKQKECVLAVPSVEMAETVVDIGNCSKDDDDQTENKWTRFGLTPLPAQKVKAPLVGGPHIMANIECVLHDRQLVGRYSLWILKVVSAWWDEEKVQTTGRMLHHRGNGVFSVSGDNVVDLHEKMTKWEELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLY4</accession>
    <name>A0ABR3YLY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase, short-chain dehydrogenase/reductase family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000079">
        <property type="protein sequence ID" value="KAL1889139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27412" checksum="38F57A2028995598" modified="2025-10-08" version="1">MSALRTTGTRLAGKVAIVTGGGSGYGAGIARRFAQEGAKVVVADINEAGARETAESLPSSMSFLKTNVTDHSDWQRLLDTTEQRYGRIDCLVNNAGTTYKNKPTLDVTEEEYQRCFDVNVKSIFHSTNLLVPRLIKQGGGVLLNVASVGATRPRPGLVWYNASKGAVWNATKGLAAELGPHKIRVNSVCPLLGATGLFEAFSGVPDTPENRAKFLDNVPLKRLCEAQDVANACLFLASDEASFITGINLEVDGGRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMN5</accession>
    <name>A0ABR3YMN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000088">
        <property type="protein sequence ID" value="KAL1888634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="966"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="774"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="966"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1421" mass="151879" checksum="2B067150E4E21686" modified="2025-10-08" version="1">MNGSRDPTSRLRANLNPLRTTALGGGFHGANVTPLSAISMAQTQTPASAIQPYNPQQWAPSPAPERHHYQDPQQSPPPPPPYSPPRSQRPSSMVFETSPANISAARAPLPSTPNNHHLQQSHQRPSPEPTASQTSFAPPPGTRGASRERRFGLPSFGRRRESSEQHQQTISPSDPYTHAHQPIPPPPVSRSPQPPLQHPQQQQPHHRPHPALQPLQIPDYQQPQQAPVVPPGSRRAASTGAIATPTSARSRSSSQVRWETGMPLPPPPPGPPPSGSRSQSMSRPNQGSDPIVSGPTRRPPPAGVAVLGPVPPTPAGWFDRDLQPEGDNDIIRDGDADNYNDNATPRQVPESVAAAAAVREDHSPNRGSLVESTSSAASSSARDLAESAPSTNSTHSSHSPSATVTNGTNSNSGSSSNNSNMMLARTGAVRGGEKTLRERRNESRNRGASSVRNSIDGTVNAGIGTDGSPGHGHSHSHSTSGHARQLSNIVIPTAGSVGSLMRRPTINKSTPRSGGGGPNSGRALMSLQQQQASPRTGDTITGAAGAATPPFSPYPHSASNTGRPHNGSIASSLANSSNGVPKALPTPPLRSRASSSSSQTRRQSQSPPIPSTSTNGATLTRELAVSQTSDQFCQGSVDRFHAFAQREAAAGSDAERVRLFAEFMVAESRVRRERYAAAIGAMGSEIFDLTRDFFRPMLPAVATAPAPTTTAANGRRESVTSQGSAGVSAGTSAVEFTPQSSEPSRSHRGSIASVFRDGPASAPLVGRDMATTPDNNINNSSAIVDSNSSNSTPNSAHLPMSPTGAPPSGGWAAQANYMPSLSPILSMSVSEHHDDGSSRGRTASRWWESSEHGGEGRDGRGGHRDDSGDRLARSKRESKYMGVPKEAREALQWTDDLPEPLSGRSIRSPQYVDPGVGGSGGPVNYAAYEGSSEYPPEKVQHADYMASPDPVRTPQAMSAHFRNSYLSSTASSSTPGLSTPNTPNAGTAFHQGAPVPQTPAALDVSRLVTLPPPYPRHHPAVNNNHPDLSETRSSVRTLASMSDVEAAYDQFKLATEAKHTEDDRAHQQQTATMRANLQNEIASGRMSYAEAAAIEADAAAANESRQKERLKADFDRFQTTVVQPVNELLTGRIARATQIFDELRSRLFGETRQPSPNLPQEEGDEQPELLETLTLLKWVFEAREALHRAIYDLLTDRNNRYRDMVLAPYRRAGDTAADKLRDAEAFFAGDAATRATAFAGEALQRAEAFRDVVEANVVRGVEVQLSAFWDIAPPLAQLLDQVPQDLTGFVIQIPAAEYEETPSYHAHPLQYLFSLLLHAEKSTHQFIESQTNLFCLLHEVKEAALTAKERVPPAEGGRAVDRNAESARLTDDLKDKVRVVQGQWRAGLGETFELVKERVGGWLLETGGWDESLEDGGVGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN35</accession>
    <name>A0ABR3YN35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_008972</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000076">
        <property type="protein sequence ID" value="KAL1889317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="76"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="322"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="552" mass="58875" checksum="BBE0272EE69CE045" modified="2025-10-08" version="1">MASDGVAANGTSQPHYVTEYLQERISGQPENPFASLIPDQQIAIIPAFDLESGVTLHNVPVAYTTRGTLNAAGDNAMVICHALTGSADVSDWWGPLLGGPGRVFDVSRFFVICLNSLGSPYGSASPVTAKDGDASRGRYGPEFPLTTIRDDVRLHKMVLDDLGVKQVAAVIGGSLGGMFVLEWAYLGAEYVRCVVPIATSSRHSAWGISWGEAQRQSIYADPKYEDGYYPFDDPPVTGLGAARMSALLTYRSRNSFEARFGRNIPDPKRQQLILERERAQAANSSSAGSSSLAPQILPPASPSEGHFRIHNDGHRIKEANRFRAASAASSASGNGKGEGNESSGAATPDPQFHGPGATEETHVGIGGAAKESLTGGSAPPTSTYFSAQSYLRYQATKFVKRFDSNCYIAMTRKLDTHDVSRSRADSVAEALALIKQPTLVLGIESDGLFTFAEQQELAAHIPDCRLERIDSPEGHDAFLLQFEQVNRYILAFLREVLPDIMGRPGLALNEDGTVVGADGANGAAGGNEGSSVGKLTKSSTFGEAEVDDITAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN89</accession>
    <name>A0ABR3YN89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ADI1_2</name>
        <name evidence="4" type="ORF">Sste5346_008666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000069">
        <property type="protein sequence ID" value="KAL1889808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="545"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="545"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="594" mass="61018" checksum="C5A5CDAA89758532" modified="2025-10-08" version="1">MKMIDMNYDGLLDEAFLGASVQGMPIMAETGAAEEAVYTDPSPPSSTTSTPGAGASGRVGGGGGGGGGAAASGGRGDNTSTAGTPGGSSTNKLRVRLPASCDPPSPDTPTKPLVWIVFGGTGHMGRSLVKSALAHGDYVTTVGRTHETSIAAMEALAASEAEHGPGDDDTSPVASTSSPLPPVTTPAPGAVAGTSTTPAADKKKMRCLGALCDVRARESVERVVQRTLAHFGRIDVVANCSGYGVVGACEDQDEHELRNQFETNFMGTLHILQATLPIFRRQHELMLHQQQVQQHNQQQQQQGAPQSQQQQQNNYSSNSGSGGRYLIFSSTAGALGVPGLGPYCATKYAVEGLIEAMLYEVDAFNIKATLVEPGLMRRDDQHLEASELPGGGAGTSGGGNGGGMGRSSGNRGDNTNPLPTWGHFLIKPPSETYANPSAPSLHATRMVQWLGDRQPASVVQCAELVWQLAHCSFPPMRLPLGSYAIESIRDRMRSVTEEIEDWKHLNFPLPPDAAAAPAAAAAATTSNTAGAASTTAATATAASASLSGPASSGGSTTTTATSTALGTGSTAIGGGESVSDNKTDVDEEMLDMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPK7</accession>
    <name>A0ABR3YPK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_008399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000064">
        <property type="protein sequence ID" value="KAL1890245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="111" mass="12621" checksum="6778DF06E635C4EA" modified="2025-10-08" version="1">MCGYAVLVDAAFDDAYYGNPARPAPELDENEREEIEGGDYTYEEWLAIVTDGDDGYAPVEGRVSRDAGWCFVRLPTYSLYQFVSASTEEWDRYYQRPPLVYPDGKPLSEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ21</accession>
    <name>A0ABR3YQ21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Siderochrome-iron transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_008264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000062">
        <property type="protein sequence ID" value="KAL1890436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF107">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="64846" checksum="C3746B647D40355C" modified="2025-10-08" version="1">MADKETATVVATAVDSIDTADAINTDTSPSPRLSLEQQNEKEVITNPDAVTASAPSGVQKAEAAALVWPKTTAFGVYIWVWLLFFVVALQASISNNVVYYAYADFASAPQIAQAYILSAVVSGVLQLPIAKTLNLWGRAEGFLVCVCVYTLGLVLMATCKGPASYAAGYTLYWVGYTATNFVLTVFVADTVGLQNRAFAYALTGAPTICTAFVGPLAANAFVTSPQTNWRWAYGSFAVVIPVTCAPLAVVLKVFQRRAEERGLFVREGSSGRSVWQSIVHYLVMFDLVGALLLMAAFVLVLLPFSLQSNGVTSQYSSPTFIAMLVVGILLFPAFAAWERFGLPRKTGAPFLQWQLLRSRTVLGACVVAAVMFFNFYTWDQYFYYYIQVVYDLNVTRTGYLAQINGVATTIWSVIFGIWIRQTRHFKNACLFFGAPLVVLGAGLMVHFRGSEAPLGYLIMCQIFLAVGTGTLILGDEMAVMAAADREGVPIVLALLGLFSSLGGALGNAVAAAVYQSTFPSALQNALPGTPYDEIMGLYLGGSTAQLAFPVGSETRAAIDLAWATSQKYECITAAAIAVLFFPAIAVWKNYSVDKKQVKGTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRU8</accession>
    <name>A0ABR3YRU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007908</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF77">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="824"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="824"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="923" mass="102239" checksum="76D75FF43219FE0B" modified="2025-10-08" version="1">MESSPKPETKRKHVTTACVLCRESKIKCNGATPACSSCLNKGKECRYEAREDRRKLSLRIAVELLNNRVQQLSEFIQDHGLELPSMPPDDDKTLAGIFHPLQLPRAPFPTATTEKTADSDVSSAGRPKRRTTERTEPIVNVATSASNTTAQKNHDDTASTTAATTSPCIVATTTVSATVSSIPAASTGGLLELANVAGNMDGGPSANIQVPNQMQPPAEVAVPVPVAGNNGAGWEWSMPPDTMQHESMMQPPPFGGDMAMATSTPPMHQQQQPQQHHYQHQHQSQLPMGIPDRPPMDMVEDPGSTKSVNELVDQLSDRVGTLHIRPGGHIRFYGSTSNFNLLESPASDVAMNVHRTIRNDGPEHLDRLGLNKKVPPEVEDHLVELYFTWQDPSFHVVDRTVYEEAKVAWRERKEDTSYYSEALRNAICALGAAFDARHHPAFVTFPRSLADFFADRAKALLEIELDSPCVATIQTCVLLSSHDIGCGRDARGWLFSGMAMRLSFNLALHHDLKPYISKGVVTAAEAEVRRTVFWAACIVDHVWSFYLGQPFRMSLEGVTLEKPSGKARTEAAPTQYCPPNKDINSNSAMTPTFSGMNEHIEDVCRFQVLLFELMSPLSDALCGGDNMSKSMLLDTNYQIFAKLNQWKESLPIELRVDLTNRETAYLPHVLLLHMQYYQSVIYAHRPWMSKSYMPPHMAAQGPDVDHARKMCMEAACAIAQLLRRYEERYTLRRINIQAVAITFSAALLLVFAAVSHYQSMREDEILADLSACFRALDELAPSWDTAKRARDFLIRLQRHWERQARASLTSTSFNDETGSLNGLNNGSMDVSMTSDFSSASTARKRPRKSMRAGNGDDNDPAMWFRAETASSLGGEYWGSSSNSTAVDFDVELDFDLMLATSMEGMPGNWGNVFSVQSSNAMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS94</accession>
    <name>A0ABR3YS94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000059">
        <property type="protein sequence ID" value="KAL1890767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07729">
        <property type="entry name" value="AHL_lactonase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF2">
        <property type="entry name" value="102 KBASES UNSTABLE REGION: FROM 1 TO 119443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="64"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="292" mass="32888" checksum="1F8C0880F52B8680" modified="2025-10-08" version="1">MSSTTDITSLFANAAVPAFKCPEGTKMHFLNLGTLECDESWLLRGGNTSTLSNKNPENKRRQLVVLACLIEYPGVGLILYETGCAEDIEVKWGAPLTDVFPRTKYNVENKLPEAIKQTGNDIKDVKAVIIGHLHLDHAGGLEHFLDTDVPIYVHEEEFKHACWAVATGADLGVYLSHYMILDRLKWQTFNDAHLDIYQGITLHHSPGHTPGLVIMQVNLAKDGTFIWTTDQFHISENYELAHPHGGLARDHNAWFNSLTMIKRLQRLFDAKLVFGHDMDVYSSYVAQKKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSJ5</accession>
    <name>A0ABR3YSJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Urea transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_007998</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000058">
        <property type="protein sequence ID" value="KAL1890857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="58368" checksum="477BB2EC79788F7B" modified="2025-10-08" version="1">MGQPSFQASNAIIYLTYGAFLLLGTGIAWHLRKQTKSGDLLAGNRTQTALGSGILFSYPQLAVISGLQGVLVYALSSALPLFVFAALGPAIRRKCPDGFVLTEWTRQRYGLPAAIFLGFLTLATLFLYMVAELSAIGQVVTALTGLNGLPAVIVECVVTTIYTAVGGFRISFITDNIQGALVLGLIVIASITVGTKTHIQHQDVIDSGLLNANLLGWQLLYILPIAILTNDFFLSNFWLRTFASRTDKDLWIGISIAAVCILIILTLVGVGGLVAVWSGAYPGEGVDPADADSSVAFFLLLAELPNWVVGIVLVMSVSLSTAAFDSLQSAMVSSASNDIFRNRLGPIYIRGGVVLIIVPIVVLALKTPSILQIYLISDLVSASTIPVLILGLWDRFSLWNGTDVIIGGLGGLLTVFIFGTIYYGSALTGAQLLLLEQGLYEGDWGAFGAFVAAPVGGILFGFGSFALRMGYEFIRARKQGRPFQPINPRAHEIGAHASSSDLGADADRGTFGTTVVSVPAEEAYGSATGRSVDAYEETSGRKGPKGHKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSZ0</accession>
    <name>A0ABR3YSZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plastocyanin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_007581</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000052">
        <property type="protein sequence ID" value="KAL1891490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13899">
        <property type="entry name" value="CuRO_3_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="238" mass="26257" checksum="A919B7C0C0A21B89" modified="2025-10-08" version="1">MTYVQPKVPSLYTALSVGGANASSPIVYGSHTNSHFFKHNDVIELILNNGDDGRHPFHLHGHNFQVVHRSEEDGGVYIPDDLAETGFPRVPMRRDTVYVEGNGNFVIRFRADNPGVWLFHCHIEWHMDQGLVATFIEAPEALQGFKVPESHYEACRVAGKPSAGNAAGNTKDVFDLSGENKPPGRLPEGFTAKGYVALFFSTVSALLGMSVITWYGLIDPNVKDRGAEHQPLINEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT27</accession>
    <name>A0ABR3YT27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_007876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000056">
        <property type="protein sequence ID" value="KAL1891052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630:SF7">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="38380" checksum="EBCA8A5EA5EDE2C6" modified="2025-10-08" version="1">MATETVTATITAPAVESGRMRMDGTDARYGDWRDDLLRDGYAVVKGAIPRERALEYADKMYALAESFGYGYDRNDPSTVHSDKLPVINEKGMLLNYGACHEDFVWGVRSEPGVVDAFSKVYGTDDLIVSFDAINYGFANRTNLPLNKPWPHQDQDPDRPGFRCLQGLVNLLPNGPNDGGLIVCRGGHNTSEQFHDDIRGTEDRIPAWTKEWYGYTDKGMAWLKEHGHEWIKVEAEPGDLLLWDSRTPHYNVPATKQQDRLAIYTCFMPVADATQEDLKRKKAAYEARLGTTHWPNAMHTGSNKAMRNGEPDKVQRDRPLNDAVLSERAFKLTGIPYIQAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVD7</accession>
    <name>A0ABR3YVD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
            <ecNumber evidence="11">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RIP1</name>
        <name evidence="15" type="ORF">Sste5346_007395</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="11">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JAWCUI010000049">
        <property type="protein sequence ID" value="KAL1891851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.270">
        <property type="entry name" value="Ubiquinol cytochrome reductase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037008">
        <property type="entry name" value="bc1_Rieske_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="149"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1891851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="247" mass="26302" checksum="EE8BC7F8EFDB1F53" modified="2025-10-08" version="1">MAPLSTASRVFARSAAQAIQTSSKTSTNTTARLAAVASSSFSTSASRNDGSAATFKSPFRGTSKSDQAPDFSHYLSKKSGNANALFGYFMVGTLGALSAAGAKSTVQEFLVNMSASADVLAMAKVEVDLNTIPEGKNVIIKWRGKPVFIRHRTESEIAEANAVNVQSLRDPQADADRVQKPEWLVMLGVCTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPTYEFPEDEKLVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW85</accession>
    <name>A0ABR3YW85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_007030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000044">
        <property type="protein sequence ID" value="KAL1892518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="536"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="569"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1462"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="593"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1756"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="625"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1818" mass="203737" checksum="1128BC571C4D4E91" modified="2025-10-08" version="1">MPFLQLPSIPAPHAELPSYLAEHPNKPMTELFEPYRKYEASVRELYAQEPGHPALADPHVNVLPLFTEDTPKLQIRARDPESEPEDVKAKYIMPLPKENRRASGSPAVVPSIGTFQGNFAVFSESSLADIGWDNVVAAGSSVVNCLLPVPDEFSKSRRSLREYYHEKFCPASDVDLFLYGLTEEQAVEKIKEIEASIRDSILAETTTVRTKHAITICSEYPTRHVQIVLRIYKSVSEILTGFDIDSSGAAYDGKQVYCTPRALQSYMTQVNHIDLTRRSPSYENRLSKYSHRNFEVFWGDLDRSRVDPTIFERSFNRTLGLARLLVLERLPTADSRQSYAAKRRQERGRPPLYNAYNVGSGMHGNIKDQHEDEVAEWITPDDVNNYDTFVLPYGRKYHAKRIEKLCYTRDLLLNAEWNQKKDREVYLHRHPAFFGRAEDVMEDCCGFCPKPQTDKEKEVAEEESKIYISGKISFLKDDPGRQQIGSFNPLTDNDWTEMAYVGNTARLCQAIIDGDLEHVEDWLAQDGVDPNRRDHTGRTPLHLAVMSSTPEIVKKLVHHGARLIARVADGRTAIHLAAQRGNTEIVKILMDKSTENEAEEEEKEDQRRKAKAAAGAEKKKKGEESEGENTDSEAEEEDEDSDGELIDDEMSDDGVHSVTTASFVKVKGRDKQDTSGDAALNDSEEEPDFYDVNVIAWDRPCSALHFAIIAGHDEVVKLLCSEYGADVLLPVKFLNSYNQQPSSALLTLTLGLALPIEKAKSMAATLLSLGATCTQADLNGITAFHRYVEATDIDLVQLLMDLDKTGAPIAMKNISFPSAYYTTSPLLCAIAAGDVRMALKLLESGVPPQIDFDTWLKCAKASTAFGNSLSTFEENNKIFNMRTEQPLIVALRSPNPHIALELLERGADPDTKTKDSHNNRHYSWMPRSTNADNALAIVRDYLTALREYKGEVPKQRKPFKVAENPEAFLSTLSKESWLYVATLSDLKKVKKDMAKQTKVHEDAIAKIRKLGGEEEKKAAIKEMIETFEKIEAKILATTRQPHVVMVEKVNVNEFPPVEFTKDYEFVPHFVGVDDITEDRRLGYVQLFEAAWNGDLEAIKKLTLSAWGDEKNKKPLSVAVNDLQGNNAFSLAFLRGHHNVATAVLEIAQAQYAPEDKPKVRYELKDDRVEEDTDMESEYSYDEDEGESRTYRIIVDNDQFTIDNIGEVNMQVKGTVTPLDLLAKNAATFVFRNGKIEDYKTFSGSLFEFVFRQNDPHGLKFLLDTATHFATQKTDAKNRGSYYNFPTSEFRAAIASGRVEMLAEVIKRTGAGLPLEEMVKDSGITIEEPPEYYQGLTVYGKKRSDWAEAGRRTVTRSSGMTDSPLLFAASVSRLESVEWFLSDAPLRCYLEFTASKAAQDDKRLTNLSQAPGGFEGAVSRWLNKNSDLALIKAINCSDTEKALPIIKYLLKVAPESISAKGDDKLTPLLSAVKLGRLEAVQVLVDNGADQSKRHETTYANLLHAALFESPKAPELEKLLDILDKDAVDHMFVERTHHASWSESRTPLHAWLERTITTGYNGEYGPGRAYDGADEVIAVMRRLLSRSGGRELNIIDSAGDTVLHMLARFQKNPAFLLGLLEAIPRDLAISLLHRENAVGATPLEVAQDKFLASFVTERRDFGGQYSSLMVNNWANTAAKEFVVSVNEGREEAPMQTRITTNKTDQLKRAEETLAVLNKFLQGEVGKRQLVSLNEANDVAHRVGHGFQNKRYPVQLIKPDTEMDGNNPNNGNGNGQAAKSDPMQLAFSIHSFANSSWHTKKEEKEEEDIDAEMDAWINGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWQ7</accession>
    <name>A0ABR3YWQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HSP31</name>
        <name evidence="7" type="ORF">Sste5346_007085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="34"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="243" mass="25615" checksum="738FDD60F0B9159E" modified="2025-10-08" version="1">MSASTTLPRRALIAVTSAQASLFNGKETTGVFISEVLHPFNVLTAAGFEVDLASETGTYTPDWLSQQPDFLAGDDLKAWEDKTSAFRQKIDNMPKAADLDASRYGLFYASAGHAALIDYPTASGLQAIATQVWANGGVVASVCHGPAIFANIIDTATGAPLIQGKTITGFTSEAEDVMGLTAELKAWGQPLVEELAETLGATYKRSAGVWDDFHVVDGRLVTGQNPASASSTARAAVEVFNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWR6</accession>
    <name>A0ABR3YWR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_007080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000045">
        <property type="protein sequence ID" value="KAL1892342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="370" mass="40772" checksum="371D4F1486E9EEBA" modified="2025-10-08" version="1">MDDRGPQLAAILIALLVLSTVSTILRCYSMGVLLKRFYIEDWLAVISLLLYCIYTAAGLTSVHYGVGQHVVDVPPESRVHAVLWRWIGSLLYIVISTSSKYVVGLFLLRICSHRRWQKITIWVILGLVTVFNIMFVFFDIFSCRPIEYQWNRYADPPRPATGAQCNATSFATVTTYVAAFLNVVADWTLAVLPSYLVWQAKMERRKKISVCAVLALGSVASVATIVRIPFADGILDRPDFLYNFTDLAIWSTLEIGIALTASSLATLTPLFRKIKFFSSAYGTSRTGGESGAPGGTRPSFVRTRTGNQSRGDTRRGDGNRVGQQNGGHGGHGGHGSGDGDFGSDLELRPMERLSSGSDTRLKGAWRFEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY20</accession>
    <name>A0ABR3YY20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial inner membrane protease subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_007190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S26 family. IMP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000046">
        <property type="protein sequence ID" value="KAL1892234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037730">
        <property type="entry name" value="IMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041:SF2">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peptidase S26" evidence="11">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="215" mass="23989" checksum="C18092BB4B4B8251" modified="2025-10-08" version="1">MALRSMWTRMRAGRAAFSTTASAAASASTKSKESLPPPPGRQTFTRQFVFRLLGLATWLPVAIWFNTTVAEVTRIEGPSMYPFLNSRFNESLERDWVINRKLYAQGGLQRGMIVFLRSPYHPEVVSVKRIIGLEGDIVQTKQPYPTAYVRIPAGHMWVEGDAGVGKSLDSNTYGPVSIGLITGQLTHVLLPFDKAGRVKWWEYPVEDRISATPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC5</accession>
    <name>A0ABR3YYC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta/gamma crystallin 'Greek key' domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286656" description="Beta/gamma crystallin 'Greek key' domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13148" checksum="BC7675A0745DE295" modified="2025-10-08" version="1">MKPTTILLTFLGIAAAMPDPATESTDAVAGASRRRRLEITFCRIENFEDCDIIQAAEHDLCNAVPASLNDRIRSISFHGADQCTFYNDVGCTGRSFTDAGSVPEVHKKFRDRISSYRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYL8</accession>
    <name>A0ABR3YYL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NSA2</name>
        <name evidence="9" type="ORF">Sste5346_006682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000040">
        <property type="protein sequence ID" value="KAL1893002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="263" mass="29929" checksum="36946BE2735F01FE" modified="2025-10-08" version="1">MPQNDYMERHLKLHGRRLDHEERLRKKTAREGHRKSKDAQNLRGLRAKRQQEARRKEKIQMKKTIKAHEARNVKSSDAPRDDEDGEALPHYLLDRAGERNAKALSTAIKNKRNEKAARFAVPLPKVRGISEEEIFSVVKTGQKTKKKAWKRMITKPTFVGPDFTRGPVKLERFIRPMALRKKKANVTHPGLAVTVLLPILSVKKNPQDPLYTRLGVLTKGTIIEVDVSDLGMTTTTGKVVWGRWAQITNNPENDGCVNSVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYR9</accession>
    <name>A0ABR3YYR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">High affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HGT1_3</name>
        <name evidence="10" type="ORF">Sste5346_006350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="11"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="461" mass="49989" checksum="9B109304E05C8916" modified="2025-10-08" version="1">MGYIITNVYALAAFLAIGGLLQGFDVSSMSGIISYPKFKEYYGYPDANVTGGITASISGASFLGCFVAFALVDRVGRRVTAQIACVLFVIGAILSSASINVAMLIVGRVFSGAGVGMLTSSGPVYLAELCRKEIRGRVLSLQPWASNWGALTMYFVAYGSMQTETTAGFRIPWGVQAVAPVVLFTALFFFPQSPRWLASQDRFEECLEELARLHGNGDPDAPLVQAEYAEIQEAMQLSRHMGAVKWSELVQRDNIQRIMAGIFIHIWTQLSGNNAILFYVSYVFQMSGLTGNISLIAAGVQYAVQVVCTLPAIIYIDRLGRRPALMIGSALMAVFLYSTAATMATNGHYVPGGLNGTKAVSWVINSDAHNAQRAVIACTYLLVAAYSCTWNPIGWAYPPEIFPQRLRGKAVAVATSANWIFAFANNMDAIFTAGVRAWQTSNLPDRLDYAVDDAERGKLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYV0</accession>
    <name>A0ABR3YYV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Small glutamine-rich tetratricopeptide repeat-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sgt2</name>
        <name evidence="7" type="ORF">Sste5346_006381</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032374">
        <property type="entry name" value="SGTA_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16546">
        <property type="entry name" value="SGTA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="6">
        <location>
            <begin position="283"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="377" mass="37438" checksum="624C76311A884E38" modified="2025-10-08" version="1">MSSLTSKQRLALAICDFLSTSSADGTIAADERDSVEVAITCVAESFKVDPTDKAAVKEAVGGQSLEKIYSVYEKLRGAAPAASAASAGGAATSASASASATTDSGSADAEPSAATKKEAEALKSKGNAAMAQKDYASAIALYTQALALHPRNAIYLSNRAAAHSAAKDHASARTDAEAAVAIDPNYTKAWSRLGLAKFALGDARGAMEAYQQGIEYEGNGGSDAMKKGYETAKRRVDELDEEASLTREGGSPSAGGAGGMPDLSSLAGMFGGGGAGGGGGGGAPDFASIMNNPMFASMAQNLMSNPDLMSNLMGNPRLREMANQFGSGGGMPDLSALMSDPNIADMARNMMGGAGGGAGGAGGAGGAGAGRGSGNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A2</accession>
    <name>A0ABR3Z0A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isomerase YbhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_006333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000037">
        <property type="protein sequence ID" value="KAL1893505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="43679" checksum="E5D993A0ECD72A3A" modified="2025-10-08" version="1">MPSNYVFVGSFVMPKPGDHDGLHVFRADTETGALTPVASYIPSLNVGTFAFDGQRSVLYVIDEVLSTAEFRDAHSCSSGGGGQVYAFSLDKATGKLTELGHWPSFGTQPAGLALTADNSHLIVSHFTSRTVTTTVTGDHTSGFALTPRYDDATTVLFSLEGDGILGNNGKPVDVYVHPSHASSPPACLHSVRGPKNGAFFVECDMARDQLITLTVDSAASSLNIQEVRDVPVRDAHAHSGPRYSAFHPTLPIFYVNYEYSPIIETFSYAKTSPKDVKASETRSPSYTSVSTVDVLPGELPGLDQKPGVLLSDLIVHPSGNFAYTLVRGHNVVSGFKVDGETGALKRIQTAQLGGNSPKGCTIGENGRWLYIALSQSSAVEVWRIGDDGLLEATDSTVTVPRPSAMLAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1C1</accession>
    <name>A0ABR3Z1C1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_006491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000038">
        <property type="protein sequence ID" value="KAL1893314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368:SF1">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972437" evidence="2">
        <location>
            <begin position="22"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="316" mass="34091" checksum="83FDB3453D586CB7" modified="2025-10-08" version="1">MTRQLRRLAAAALLLAPTVMAIELNLPSYHYGDAIQVECMNRSSETGEHIQLANNEIQWVPFPVCNETQKPLEFHYGIEGEVNCTIPLVTDPFFHLLEFYLHADAPLMCRLANRPPAHIETIGEKPPVPEYVPLVFALAGTLQMSHLHIASHLNVLLHSTPKHHIHPHDSGVIDSGVAYSTSPLGHNVLDGASGEVKSTGGRTAAAAEHSRRLIIGDPLPLSFSVRWFPTPHLPKTEGRVEWSGMGSHIGPSTVFYSLVSFLAGLIVSAVYFFGTVLPKRLKGRSLGGATPLGYGIGTGGGGVGNGWGMAPKRALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z226</accession>
    <name>A0ABR3Z226_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP:AMP phosphotransferase, mitochondrial</fullName>
            <ecNumber evidence="5">2.7.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Adenylate kinase 3</fullName>
            <shortName evidence="5">AK 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">ADK2</name>
        <name evidence="9" type="ORF">Sste5346_005656</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:13749"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adenylate kinase family. AK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.10" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000031">
        <property type="protein sequence ID" value="KAL1894684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03169">
        <property type="entry name" value="Adenylate_kinase_AK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036193">
        <property type="entry name" value="ADK_active_lid_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028586">
        <property type="entry name" value="AK3/Ak4_mitochondrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57774">
        <property type="entry name" value="Microbial and mitochondrial ADK, insert 'zinc finger' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="8">
        <location>
            <begin position="191"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="5">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="5">
        <location>
            <begin position="190"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="64"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="200"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="288" mass="30923" checksum="43A90AD4EB9A3701" modified="2025-10-08" version="1">MRIRKAARVILIGAPGVGKGTQSERLLGRFPQLAHLSSGDLLRHNVKTRTPLGIKVESTIKNGGLVPDDLILRLIRNELSTRGWLTHNGRPPIMTLASAGLSSGADAESAADSDAGVAAFLSQQSTPSPTDSTSASSSATGLSSDPSASFLLDGFPRTAGQAAQLDAIVPINLVVSLKTPFSVILARIGGRWVHEPSGRVYNETFNAPKVPGRDDVTGEPLVRRADDSEAVYRARFEKFEETSAPLLDHYARQGVLWEVEGMSSDEITPKLMAEFERRFCTGAEKEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z228</accession>
    <name>A0ABR3Z228_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_006033</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000034">
        <property type="protein sequence ID" value="KAL1894247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1073"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1247"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1270"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1365"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="377"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="777"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1151"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1442"/>
            <end position="1673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="466"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1011"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1013"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1030"/>
            <end position="1040"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1674" mass="184065" checksum="372532A351C44101" modified="2025-10-08" version="1">MSSPPNWTNHIWPCYSCCQQIWIPESATFGDGCPGIVAYFPVWIALLVFVGRYALQPLWNRRPVWLRGFATEEDELGLKNGRLPPSNGAASQQSGRYNVQNADNTDTDVEAAASNSAVEIAVEEPTEEAVESDTDNVTDSSASSTVVGFGRRNSVVDVRPVSIGGGFASLTIQSWHLMSVTLFLLSVAGVATSLILTFAAGHGYLYLTPVVPCFITSILLAVDRPRSLPGSVLFIYITTLIVQIALLFGVPVLSQWPLSLTWLAEMSVTGLSIGIMMVMPMRDPRLGTGRENDKIAGLFETPSITKRSPEDNLNLYQWMTVNWMAPVISLGASRQLQDEDVWHLPFEFQHARLYRLFHDVKGSVTTRVVKVNAPDLIITSFLGILDSVLSMLPIILLKQLLASMEGPNASIRVASVYAVFICITNIARAQAGIFSLWFTRRCYERSRGELITMIYEKTLRRKAFTFPGHTDADSSKKGGKGKRRRDSAAPRPRMLIAQGGGGGGGGGGGGGRAAGARGPGGGGGMTEIANSVVSGSAPASTGKILNLMRNDVYEVAQRFWEFPTLFTKPLNFILSIFLLWNVLGGASLLGILVIVAAQIINVYIVKVLVRWELARRAVTDIKLQVTSQFIESIRHLRWYDWQDKWLANILTARQKELNYRVITNLIQKAISVVNQLAASFFPVAAFYAYTVIEKRPLTIDIAFPALNLFNLLEQSLRELPDLITVLLNANVAIRRIEAFMAEPDKEGIDDEQRDVLTQAPEGDLVDGIIRPPGPLYIGIEDAAFAWPTAENPILTKVNFTAEGPGLTVICGKVGTGKTALLMTLLGEMDQHGGTRTIPKETFGYCAQTPWLQSMTVRENILFCLPYDEVRYHRVVEACCLLPDFAEFEAGDMSNVGENGIGLSGGQKARVALARAVYSRARILLLDDPIAALDHNTAESIMKRLFATSGLMKNRLVIFVTHRMDLAANYADQIYEVSDEHGIISKIDADQVRRTQGSSAAPSTLVAIGEESVASSSGDNDGASSSNSEEDNAKPDDTPDKVAKNKFIEEEHRAHGGVMLSVYWRYIKAGGLHWWLMVVLSFVGFRVSKLAYFYFLKVWGEAYGSETVTTVVKRAIMSVLPPSAQVLVSGAHGDEDMFSVAMHHGALNGTGWTDKNFGLPDPEVDVRPWLFWFTVLALSSLFFRTFADTILIAITYTAGKQVFQEVMIRVSTAPFRFFDVTPVGRLMNRVTSDIGTIDGAIAQQIHRCAWFVLNWISSILVIASATPTFLVMAIFMTSAFVLIFFYFLPASQSLRRLEMVSLSPLMSNFGTLLEGLTTVRAFRVQPHFQERIIRTTDAFQRMDHFYWSLQAWLQWRFNALTALSTFALTMTALGTGLSSGLVAFVLTAAANFVNSTQVLCRRYGELQMQFVSVERVTELLDLDQEPVGDVDPPAAWPTTNDDIVFDNASFRYAPHLDPSLREINMRIPAGSTVAVTGRTGSGKSTLALALLGTVLPDNDETSQGSIYIGAMNVATVNKHTLRQRISFVAQDPVLFPGSLRENLDPVGDHTDEECELVLRRVLADAASDFTLNSRVDGGGKNMSQGQRQLIGLGRAVLRRSPIVILDEATASIDKKTAFQIQEVLREELRNSTVITIAHRVEAVRDADFSVVLENGRVIHAAPVEPESVPSSDHDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2N2</accession>
    <name>A0ABR3Z2N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="3 10">5.1.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NAD(P)HX epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_005567</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032976">
        <property type="entry name" value="YJEFN_prot_NAXE-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232:SF10">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="11">
        <location>
            <begin position="11"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="127"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="236" mass="25649" checksum="BE3F97A15D7B3EDF" modified="2025-10-08" version="1">MAFKTISAKAAAALDKELMSSGAFSIDQLMELAGLSVSQAIYRVHPPNNGRRILVACGPGNNGGDGLVAARHLSHYGYQPTVYYPKRSKNELYQRLSKQLEDLNIPFTEDFPAALGSADHVVDAIFGFSFSGEVREPFPAVIKALEETKVPVTSVDAPSSWSIEDGPPEFGVGCNFHPAVLVSLTAPKPLVRHFKGRHFIGGRFVAPSIAAKYNFDVPRYEGIDQVVEVDTSEEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3G5</accession>
    <name>A0ABR3Z3G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell wall assembly regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SMI1</name>
        <name evidence="4" type="ORF">Sste5346_005324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KNR4/SMI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009203">
        <property type="entry name" value="Knr4/Smi1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017023">
        <property type="entry name" value="KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="3">
        <location>
            <begin position="150"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="404"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="561" mass="60748" checksum="244EE3A5BA9CBEE4" modified="2025-10-08" version="1">MTSNDRHSDFNSPYRTGQHVPLNPENGHMSGLATVATASESRHDVSSPYSDYSQNPLDRVMSPTTRPGAASPRIPQGNQAPYSPGARSESARRQTQVGDGFEMQSPTGEIPMQSFQDGLPPAPPVASSWRRIDKWAEENYPELFDNLCEGCTNNDLNELEHVLDCSLPNDVRESLQQHDGQERGGNPTGIIFGCMLLDCEEIVQERDQWRKVNSEYLSAAAAAAAAAAAARPGPLKSMDSFGDGAPSASGSARSSVDHGEASSSRSAPSVASNGTNSTWRQDLLARQQSVPPGAIQRAYAHPAWIPLARDWGGNNLAIDLAPGPRGTWGQVIMFGRDYDTKYVVARSWAHFVALVADDLSSGKWFIDEDSNELKLREFKSARVEPPYMDILRWRMDQKYNRRVNKRRTVVPGAAGSPTNAGSPYASPTDAQPSDRGRPLQRLSVNSPLASPSRPSGYTNSKLSPLARVTEETSLPELNMVLPTNEESETLVEVTTPRATAPAAAETTATPKPKLAVTTTIAEASANNVEPENDENAKPNKGKGRQATVESEAEDAMKTIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z465</accession>
    <name>A0ABR3Z465_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="371" mass="38166" checksum="B3FC0FABD0C0EC31" modified="2025-10-08" version="1">MDLPEVVPDSSLEAASHGHYQQHQQHHGWDHGEKDPKYAVPAAADYKSDYNAPSVHYDAGLIPVHSVHSFNIDDTGHLVPPNGAGAGRKTICGLRPKVFWLLLGIGLVVIIASVAGGVGGGMMAARSKKESNAQVAASPAGVDSSSSTATSTKKPAANGTGVGGKSDGGKSTDGPVNSAEASSTGGNASGKATGTDSSKAAATATEKSTETDKKPASSPAQKTVTTGTTIVSTTTKQPATTPTAPSHEPTTSKAADPTTTKTTAAPAPEPTFLNNQTYSLTGFAFQAFSGSDYSGRVSDVVRDEGFLDLSFSSNSYVWLPNGADCCITFCSDDTTAVGWWCDERRQKDASSAFPRVWIGCGSAAHKEHACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z488</accession>
    <name>A0ABR3Z488_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone deacetylase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CTI6</name>
        <name evidence="6" type="ORF">Sste5346_005470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000029">
        <property type="protein sequence ID" value="KAL1895049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053051">
        <property type="entry name" value="HDAC_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47793">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47793:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="227"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="601"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="232"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="374"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="416"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="436"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="470"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="616"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="680" mass="72538" checksum="7E5593743E52745B" modified="2025-10-08" version="1">MAGPDPRRSSRARTNQPVSRPSSTTSSVSGRIERHSSSKHHQFVKTGSPQKSSTSTASLASEPPDDAAGTDDNTPPPPTRSRRAAHHSNVIKDDEQDQSSVVVSEIEMTNDGDDIQEDDEAVRCICGNEDYPGLPAAEDIEQAAKDGYDVEAIFPAVVTDDLAGFFVQCDICKVWQHGACVGLINDATLPEEYYCEECRTDLHKILPGTNNHRCSIYLALNRRRSRTGSFNKNRERTPQRRDSSKDSKDGDRDIGPDGGRESKQSRSAAAAAAKRRSTMNSRDAAYDEEQLLIALAASREDASDPADPTPRRPKRSRSDSEEKADMKRQRTSSRSVSPPGDKSTLADDSDDAMATRNGSSKKASRSAALARSQAQRERAEREEKERQRAEAASKRNGRAERRRVDDSDPSDEAPLATTRAAAATRTTSAPAPPTATPATASTSGNTSATPTNAPSQSATPAPATAARSAPPRPSQPSPETPPPTSAPAMAQSKSKGGRPTHKKKGRNQYTKERDAREELNSMTRSRSRDVPENGQGKPGSSGGGGGSHGNQNSKSGSRSKGGNANSRVSLTEMRRRVSAMSDFIGKTQIDIASGEYLASAVATPDGGKAGSGSNGNGNNVATNPSSAATTPSSTSAPQLLATSNGVSSDTPEKDFKKLPLLEMMDTLTRNIIHWQNQYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4X2</accession>
    <name>A0ABR3Z4X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000030">
        <property type="protein sequence ID" value="KAL1894853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="357" mass="38807" checksum="B160DA21CBCFAC6F" modified="2025-10-08" version="1">MTNFNLDVVQRAAAEAVQAANSPAGRTALASTAAVVLGLTAVSRFNRLLSNYAVGNPLFGTTSSQWSDWSKEIVLVTGGSSGMGRIMVIEFAKRGVTVVVLDRQAPLQKGDARDAYKSIGENDDDDRFPGPAQGVHFYEFDLTGPDSELEELAARIRREVGEPTVLINNAGIGHGLSLLEATNDQMRAVFAINAVAPIRMTREFLPSMIRNHHGHVVNMASMASFVTIASNVDYSCTKAGLLAFHEGLTQELKYRYNAPEVRTTVIHPHFVKTPLLGEAAIEPSAEIKRRFQGDLLDPRTVAVGVVEHVLAGKSGQLFYPPKFAVATILRGMPTWLQERVRGQLSPILTRPMAMGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Y9</accession>
    <name>A0ABR3Z4Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_005794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000032">
        <property type="protein sequence ID" value="KAL1894559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF13">
        <property type="entry name" value="ASL1-LIKE GLYCOSYL HYDROLASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734971" description="Asl1-like glycosyl hydrolase catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="3">
        <location>
            <begin position="189"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="418" mass="43283" checksum="F1A9EAEC4DF0D28F" modified="2025-10-08" version="1">MMNAKIVALVASLLAQQAVALNAHRHAHNEYHAKKDVTYVNDVVTVTDWTIVTVYEDSPAQTTAPKAIYKGAAHTEKLTSSSTSVNSTTSISSTTSLSSSSSPSSSSSSTSIYTPTTLATSTKVSSSSISTSTSSSAQRQIEAAQAQIPTTVIAAVAAVPNTSSTSSTAAAATTVASSSSSSTGSGARGLAYNSGDLLAPLLGSGTKCTWSYNWGQTADSSAPESLEFVPMLWGPTHSDGWSSNAAAAIASGATSLLSFNECDNVGQCNLDAASAASAHIEYMNPFSGQARISTPAITNSNVAGEGVDWLTAFLEACNGQCAYDFCAAHWYNSPDTDDFLAHLVAVHEACGKPVWITEFAPTGSDEEISAFLTTVMTAMDTDPTYSFVERYSYFMAATGSLLSSSTTASSYGSTFAYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z529</accession>
    <name>A0ABR3Z529_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="4">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_005236</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="4"/>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="532" mass="58159" checksum="45985E760D07A48A" modified="2025-10-08" version="1">MTTSAITNGNGHHANGQASNGVNGVNGTNGVNGTNGTHAANGTNGTNGTHPTNSKHTTSVHSRLRPAVPDEIQDLVCVGFGPASLAVAVAVHDALEAGTLKEAPKILFLEKQHRFAWHAGMLLPGAKMQISFVKDLAMLRNPRSAFTFTNYLHENGRLVDFTNLGTFLPARAEYEDYLRWCATSFDESVIYNSEVVKVVSEQAQQNGDSPVSTFRVVAKDVASGTEHVYYGRNVLMATGGKPSLPPVLPTSHPRVIHSSQYAHQLPAILNNPQGRYRVAVVGAGQSAAEIFNNVQELYPNSETHLVMRSEFLKPSDDSPFVNSIFNPEYIDSLYPKSATYRKNLLSDARPTNYGVVRLELIEHLYDRMYHQRRLLGTDEKKWPHRIHGSSQVARVESDNKESLRLFVEPFQNGSTSAETEILDVDLIVAATGYQRSSHVTMLQGLWPLLPAKELQKADDATLGTWEVNDAATTKVLTVDRDYHVKFDSGRIAPGSGVWLQGCCEGTHGLSDTLLSVLATRSGEIVESIFGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5J9</accession>
    <name>A0ABR3Z5J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="326" mass="35908" checksum="375F9002BBD9BF43" modified="2025-10-08" version="1">MADKYPNRPLIVLGTAGIGDSSIDPELLLDTPEQLGPFLDEFYNRGYRVIDTARNYPPGAPATAEPRIARHNTDGRFVVDTKVFSFTPGDHNEEGLAKSIDGSLAVLGGHPINVEYLHVPERTTPFADTLAAMDKYQKEGKFKKLGISNYPPEEVQQLLSIAQEKGYVAPSVFQGCYNPISRDIEKDLFPILRANNVSFYAYSPAAGGIFSDKKRPGNRFESSGMVGTIYTSMYKRPSIEAAVERVRKVAREHNVPGHDASLRWTVYHSQLLGEHGDAVIVGASNLEQLKKNLDAIEAGPLPQAVVDAVNAVNDSINDEDKQQYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z623</accession>
    <name>A0ABR3Z623_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_005181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000026">
        <property type="protein sequence ID" value="KAL1895709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="50788" checksum="36352A3BBC6EAEDE" modified="2025-10-08" version="1">MATDLESAVATARAAWLSNVTVADSNLATRQLLGLSNLLLDHRDELVTTLVRVYGHSRDVWERELAIIQLDIVAHIKSLNAKGKTTGKKSSKQLSAASKVPKGVSLIISRSENPLRHALAPLAASIASRNAVVLAVLDDNEVIRLFKDKAAAYLDKFALHLVSLDRDEVPTLPPVDHVLICDETPEPWPTYLASTTPSTFVSTAAGYSLAIITEGPVRGPDVAHLVANARSGIRPFDGVDAVFVHHASFEAVTNVVSADNGSSVAPRDNKAPLGLTQITKTVLAWNPGQKDGQDLSLAEAIAVARQRSALLLVNSSSTEEIVDNINQLHNVAQLTVIGAPDDKVTADYIEQWTSSARFSTSSFPTATPLTGLYPWHTGLEQPNDTLFSSSLFSNTRLITHGRENALPDNVNVEKIRALYEKAIPVLEPEHPGGRIDFFVQVEYAFKTAAALVTVGGIAAVYFGVKHFRHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6H9</accession>
    <name>A0ABR3Z6H9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proteasome activator BLM10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BLM3</name>
        <name evidence="9" type="ORF">Sste5346_005229</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032372">
        <property type="entry name" value="Blm10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16547">
        <property type="entry name" value="BLM10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 N-terminal" evidence="8">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="7">
        <location>
            <begin position="395"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="6">
        <location>
            <begin position="1939"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="926"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1402"/>
            <end position="1422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="2027" mass="228873" checksum="62D4A8879B14E079" modified="2025-10-08" version="1">MDEIEAHAPTPGFLAAAATSSHDFLAGNFSVDTISRATSPGVPSSITPDEVGKKRYRPRTFSYFSQLPYPVEDESERDTTLNLILKNLYIAIKAEDFTPGALHWTRELQGWLNLKFEMTREQRASLAQLYYHLALAPGLETTATDRFCRMLITLTKKRHYLRPGEDLTLDWRPLWKQLKSITLPSETAVHQSVQARVYKQVLRLCLHAQAYLDPSDRREMLDEILPYFSTSDMSNAFIVIGLITIMVPTAPAPPTAYMSQPSDFLPTYFHLWSLVNRSKAVDISFVDIFSRMSRDYLAYQHVPFTAHGIFSREQSDLIFTAILRLTEIPVGQANSPYVSTLDYSSGLAVFLDKDRKKYPVPYMAARWIVHALSPLCLDAQDDDNATPASSILTGLEGFLESIDTFFHPSNQGAWTSFLAQFTHYLVDIFVNRWNREQSGELDLPADRRLTPEVKRRFVLALRDVTFMGLFAKSQKTAGYYYVTLQSLAFLEPGLILPGALQRFYPSLQGLVEVHRTTASLCGLQVIAHTMSRVKGFRGHITALLALALPGIDANDLGKTQLTLAFIQTVAYSIPFASLINDEDADNGVYDTGLAMQWVRGEMERFEREGQDIQLDYDKELTDEEEARIVRSSTAGFGEFLIALLGKIFTLVENLPDLSHFRSGSPEDHVINSLPSALTPVFAALSPELFDMAVEKIAAFVASHVVHQARDSMAWIVNALCRVNPEKTLKKFIPMLIVNIRNEIDDNGAASDRSSGADVLPRDRALVWYISILSMCVVHVGSEVLKYKKELLDIGDYMQDKCKGLATIHISNYVHHLLINLTNTYPIDNHMFEPDVIKGGIGLQHWGYITAPSDLTIKWYRPAQPEIQFAAEVFESQVISAKEKMEALMSDNPPVSRKGKNKEWSDELTRALSRIRQVISGVSPLFETSRASTTTTDGRGGPVKEDTDDVEMQDASAPPTAIASIEGNDQDTAIDEDVDPLAEVASDDDLKREFSYPYGYALDRKSILFERIHELREAVGYLLDRTHKFLVTYQEDDVACFTDLYTTYRTFIIDVGFERTSRPLDRLLRLYRSDIASFKINGLRKVYPRPLLVKRADAYQLQRVKYNTTYRLTSQLDKQLLKDLAQSCTSVYADVRRAAQSAQESSLKVLIGSRPVVIPIVLRTLKESLDNVDHDRIKGAMYTLLFTSLVKTMIRDWRFGPTLIRLYIRSADVDKASIQQMGANALFPLLEFGKAFERMVIVNEATVATITPTSKADLEDSATKIQKRHSFILERRRKVEQKKAELGLELIEIAANSHWKVASRCAVFANNLCLRFDTLAPPAFIDLAAKGAISQHPTLRAGYQNAFANIFMFLALRSCYKNDYRNYLLDNERMDNRLEIQVPVTGGDAAWTNKYLDSFAIQSPESNGHGTNGSSTNTNGDDTNSYFVDSDYPGWLVWGKSFTGYSADPKIVTDKYDSVGTGAREQIGKILTKDWLKQYFDFMKQEPRDANADRFKVRYVSMLSYVFELVHSGVAEVTFDEVKELVRGVYDDGSDRHQHRATAEIVAALLSVGPDEPKAYRDRAWEFAGPLLLDIINDKLTPENLHYWMTCVHMITGIRDPRRARELVLGLGSFRLDMTSNAAFKESSKVTLLEFLISDAGWHFRGEKPIVADMLAHIDHPYKAVREAMGRVLATIFRTRYHESFPNVADLLEQNKAASSVGIRPYKATSEFASTVTEVFKRLEAWRHERVPGQQEQSSYTSGSKTVLTWLDWMLSSQECTELVQFFPEPFIDQLLHMMDVKEDPELMRLAYHVYRHLPNIPLREGEDDAFIRKLIDVGRSAPSWHQRLRALINMQVVYFRRLFLSRPVQRKLLFTAVGDMLADAQLEVRDSAAATLAGMIRCSPASIRNPIIQSLMQRFKEQLEANPMPKRKRSVVAGLAGSEGGSGTETPIDTKRQVIRRHAAVLGLGALIEAFPYATPPPSWMPEVLSYLATRTANDPGVVGNATKSILSEFKKTRQDTWVVDQTYFTPEQLEDLEGVLWKSYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J3</accession>
    <name>A0ABR3Z6J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_005244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000027">
        <property type="protein sequence ID" value="KAL1895438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF4">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="36808" checksum="99FCEB399139EE0A" modified="2025-10-08" version="1">MSYASPVSGDGGTPGSYPVFPIPIPVIVARGFQIFLSFVICVMAGLLMHGLVLGPYAFAFVCGLFTLIIAIYAIVTEKATGARAAYNYWAVLSLDLLMIIFWLASMGANAALRGTFKYDTVADCYDDGSTFNANTCYTSKKRDGLPLTKRYAVAGKVALAEISAIAGLSAVQMLLFVASFAYLAHQVRLHLQAQKQGIQSNDAGVVEMKGQQPPPGGAGAYDPDYAVYGAAPGGLAPVQPYSAQTQVPPQSQSYPNQPMPYTSASYDAGGVSAGYAGGVQATAVYDPHAQAQAAAYAPSQHIVSPTATPAPEYQQQHQYSTAPAAQGTPEPYYSTNQTHQQPYYPPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6L5</accession>
    <name>A0ABR3Z6L5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004664</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF11">
        <property type="entry name" value="AMIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="80"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="550" mass="58728" checksum="E0A34C1648077640" modified="2025-10-08" version="1">MTQGKSWEALAAQKREQLAASLPKEWLVPDELLPPADQDDITGWPAASGWFTAEELRITESTASELVPQLASGALTSVAVTQAFCKRAVAAQQLLNCLAETCFDRALETAAARDEYFARTGKPMGPLHGLPVSLKDNINVKGLDSTVGFASHVGDPSAADSALVAVLEAAGAVPYVKTNVPTAMMIAETVNNVFGRTINPLHRGVTPGGSSGGESALIAFGGSCLGVGSDIGGSLRIPAACTGLFTLRASGGRFPVRNCRSGMPGQEAVMSVNGPLARTLDDIEAYTRAVLDGQPWLLDSKCLPIPWRPTVEIPKKLTIGVLWHDGVVRPTPPVARALKLAVARLAAAGHTLVDWDPIDQAEGAHLLARMFVADGGKTIQHELDRTGEPLRPEMHMYGTATELGTADMWKLHMERSTFQGKYLDRWNAAGLDALLCPTIPFNTVKHGMFEHVGYTGVYNVLDYAAMSFPTGLVVDKTIDQPVDVEHPDYTPLSESDKKVSAGYDADTMHGLPISLQLVARRLEEEKVIGMCRSVLAAISDEPKANGVNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6N8</accession>
    <name>A0ABR3Z6N8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">rRNA-processing protein EBP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ebp2</name>
        <name evidence="7" type="ORF">Sste5346_005334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="359"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="453" mass="49730" checksum="60EF86A6F5E36B64" modified="2025-10-08" version="1">MGRSKLRVALAAEKGVDIKKLKEKKKFKARQKEEAKKASAARGEDDEDDDDEEDDEDFEDVDEDEDDDEEEEDEERNALIDDEASESEDEDDDEFDEEISPDFIAAMDDSDDSDSEVEMESKILRPKKEKADKAEKPKKADKKVKGGDDDEDEEDEDELAWSDVDEEERAGLVVRQRQTINNTAALTAALLRIRTFAPTDASIPFQLHQSITASVPTTSHPDGTPMDMSDDKVREQALYSQSLAAAVEARRRLRKEGVPFTRPTDYFAEMLKDDGHMAQVKAKLVEAATAAKASAEARKQRDLKKFGKKVQVEKMQERQKEKKETLEKIKSLKRKRSEFGTTSTHESDAFDVAIDKELASSSKGAGGRGGAGGRGGAAGGVNAKRQKKNEKYGFGGKKRHAKSGDAMSSGDLSGFNARKMKSGGGRGGRGGSSGRGAASRPGKARRQAAASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Q2</accession>
    <name>A0ABR3Z6Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycogen synthase kinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gsk3</name>
        <name evidence="10" type="ORF">Sste5346_005349</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000028">
        <property type="protein sequence ID" value="KAL1895204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="394" mass="45365" checksum="063A10F8B46FC927" modified="2025-10-08" version="1">MSQNRPSAFNNLRMGEVVREKVQDGVTGETRDLQYTQCKIVGNGSFGVVFQTKLSPSNEDAAIKRVLQDKRFKNRELQIMRIVRHPNIVQLKAFYYSNGERKDEVYLNLVQEYVPETVYRASRFFNKMKTTMPILEVKLYIYQLFRALAYIHSQGICHRDIKPQNLLLDPTTGILKLCDFGSAKILVENEPNVSYICSRYYRAPELIFGATNYTTKIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKILGTPTREQIRTMNPNYMEHKFPQIKPHPFNKVFRKADANALDLIQRLLEYTPTERLAAVDAMVHPFFDELRDPKTKLPDSRHQTGTLRDLPPLFNFTLHEMSIAPTLNHKLVPPHMVPVLQSQGLDIDNFTPLTREEMMAKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6R2</accession>
    <name>A0ABR3Z6R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 10">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Sste5346_005051</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWCUI010000025">
        <property type="protein sequence ID" value="KAL1895952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="12">
        <location>
            <begin position="18"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="11">
        <location>
            <begin position="139"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="433" mass="47056" checksum="2D6A453F16419239" modified="2025-10-08" version="1">MAQSWLDIPAGSDFSLINIPFGIVTYSGTSTPRAAVAIGDQVLDLVVFSEFDGFDGLADIQPYLHLFDEPTLNSFAALGRPLHKKVRAYLHDVFVKDGPFRERLQDNAQLRSASLVPLASVQTHLPMHIGDYTDFYVGKHHAFNVGVLFRGPANALQPNYTHLPVGYHGRASSVVVSGTPVRRPWGQILDTDKKTPIYHPSKRLDIELELGAFVCKPNYLGSPIPIGKAEDHLFGYVLLNDWSARDIQAWEYVPLGPFNAKNFASTISAWVVLADALEPFRTDGIQNTSELQPYLKPADSSVKPMFDINLEVDLKPKGVAASSVVSRSNGRHLLWSFPQMLAHHTVGGCPLNVGDLLGSGTISGPDDGTQGSLLEITGGGSKTVNVGGVERKFLEDGDEVVLRGWCEADGQRLGFGECRGQILAAWANGVAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7T2</accession>
    <name>A0ABR3Z7T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_004883</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000024">
        <property type="protein sequence ID" value="KAL1896141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="169" mass="18668" checksum="C95D821EBCC0F715" modified="2025-10-08" version="1">MQWRTRKAHGVQGGKYHGLSPLQIGRELLLDMDPLGLICFAGRFLLVLLPLTISDYAPDRYHTPYIIAMFVTGAVLLLLWPVVETRVPRPLIQLRTFFFNPNALVPTAIYFIDEVAYAFISVPMLQWSEITLGLSAGNATYLTYAQAASTTKTVRGKSAGSSSSSSKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8U0</accession>
    <name>A0ABR3Z8U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G2 m phase checkpoint control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_004611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000022">
        <property type="protein sequence ID" value="KAL1896577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="431"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="75"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="515"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="62637" checksum="A374D516803133E7" modified="2025-10-08" version="1">MSEFLGARISLISKSDIRYSGILHSISSEDSTVSLENVVSYGTEGRKGKPEEEIAPADQVYDYIVFRGTDVKDLRIEDGNSAPPVPPPVPNDPAILGARPRPVNNNGPQQYQQGPPQGPGPRGPPQGPGPRGPPQQGFAPNMPPPPGGWGPNGPPPANMPYPPPPGWYPPQGPGFGPGGPQWNNNFFPGPGQFAPGPNGPPGPNGPGAPGRSPQPQQPGAGGPTPPAQGGDKPKGPTPGPAELEPKSLGQPPSANSRATPTGQSTDVRKVAPPTAPAASGLPTGPKNTTQISPAVPLPAGLVNKTTAQTSTVAVATKTTESAQSSSLQSATEAAKAAVARAMAGLPAAVPQGGAAPASGSSNLDNLTRKVDEMRINAANQNNQNNNYKNNSGHYNNHNNSYNNHHHHNNNYNNQNQNHQRGRGRGGNYNGPRTAKVEVPDAEFDFASSNAKFNKDDVVKEAIASGTLEADVNAAAAAGVSSVHGSEAGGSAEAESGDAPVAYSKKSSFFDNISSEAKDRAAAAASNSGNRPGGREWRGEEQRRNVETFGQGSVDGGYRNNYRGRGRGRGRGGYNRGRGGNNYRRNNDYNNQQQQGQPQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z909</accession>
    <name>A0ABR3Z909_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Sste5346_004691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000023">
        <property type="protein sequence ID" value="KAL1896308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037475">
        <property type="entry name" value="Sos7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048781">
        <property type="entry name" value="Sos7_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329:SF1">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20882">
        <property type="entry name" value="Sos7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="204"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="423"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="531" mass="57510" checksum="D8D5B935B90A1C1B" modified="2025-10-08" version="1">MPPRTRTQSSGATSARSTRSSGTSRRPSGGADSSTDASSVDLSASTRASSVSVSASASGFNSYGSSPTPTEGAPLVPTTTPVDMGLAFGSNSTSIDSLYGPTATYVNLVHMDQMAQYLQAPETQQSLDTLLGVVKMKQDKSGNENDDDETPDYHTALDELDYLEGLFKKLRFSYKEQLTKETVVRRILELELPLLSAADIDRIVQSTEAERQQLRQIKSEGREQGAAAERLIRELAAEKRYLATAEAEAVHLPDRVLRLRHRLARLKLALRAELDAIDQVSSGGNAASTSTNHPCTTCGRSFYSEAFHQLHQAMHSVQSGKGGEEKGGSSLDFGDDAAAAAAASATAMRRCHGCTQMVPALFLDSAPPKGESHKAFHARIQKATAEAHQKLAAAAASTSTSSSHALMTEGARGSLDLTPQAETEEAVRQLQRSEADLAVLEKRVRAEAERQAVIEGEMTQSLQHLRESVGSIRLEMARIEQEADRMVQYIEEGRTYLGRSLQEQTDLFDVLLLGDDNDDDDEDSDEEMQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z936</accession>
    <name>A0ABR3Z936_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Casein kinase II subunit alpha</fullName>
            <shortName evidence="9">CK II alpha</shortName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CKA2</name>
        <name evidence="12" type="ORF">Sste5346_004489</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="JAWCUI010000021">
        <property type="protein sequence ID" value="KAL1896855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024526">
        <property type="entry name" value="DUF3807"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12720">
        <property type="entry name" value="DUF3807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="274"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="92"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="582" mass="66482" checksum="9226DE335DE11ABC" modified="2025-10-08" version="1">MATLADIRVPLISSEELFAFHESHFSIASTADFGENFTGLPEPTSEAQHGDGVGSQEVELQAEAEVVDGDEYDLETSVGVTFTAADFAASFEDGEIPDDDDEGQENEKEQQDERDKPRKKRRRKKHNTGNSNARRNTHGNGGEPKKPDLRKRTWDVVDSGLGSLDYDGTERDGGSMPAPQRRRVQYGDDSKSGHRTSPAHWEDIRNGLGGTLQQSISHYAQTLSTELDLEAKTGNGDDIIINMARVYADVNQNMPRAYWDYDSVNISWGVLENYEVVRKIGRGKYSEVFEGVNVVNYQKCVIKVLKPVKKKKIKREIKILQNLSGGPNIVALLDVVRDSQSKTPSLIFEYINNTDFRSLYPKFTDIDVRFYILELLKALDYCHSKGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSLGAMFASMIFRKEPFFHGNSNSDQLVKIAKVLGTDDLFDYLDKYEIELDTQYDDILGRFQKKPWHSFVNSDNQRFVTNEAIDFLDKLLRYDHADRLTAQEAMAHQYFDPVREPGTRERLMANPPTNGTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Z8</accession>
    <name>A0ABR3Z9Z8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000020">
        <property type="protein sequence ID" value="KAL1897047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="42"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="283" mass="31220" checksum="F4F7BC7C99A8D2B5" modified="2025-10-08" version="1">MSHSIIGAPSSVAGAATATPSARSKEREQLMSGPLMFRTPLTVATIVINGREFFIHANLLCKHSDYFTRCLRGGFAEAETQRVEINDEDISAEDFGLWVDLLYRSHFQKPDSFVLRKEETGGTLSTMQILTLWKLSDRFMNRVLAQMAEESLQHRLSLYSVEQWRKLYRTRPSSDIRSRVSRLQDAYRYCVDQELPFVNDIVNACANSPPQVYAECASLLEVDFMLLVSQRMIMDHADSALISKDQRLSSSGNKANGSAAAGAVNGGRAANGATGSASELGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA26</accession>
    <name>A0ABR3ZA26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_004197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="1">
        <location>
            <begin position="80"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="223" mass="23258" checksum="6DAACAEDFE489705" modified="2025-10-08" version="1">MGAIKRTALQKECDKAAKILKGFVEKDKIPKQVIANAKGLAIFTGFRAAMYFAGSGGSGVVFARLPDGTWSPPSAFSVRTGGIGLAYGVDMFDCVCVLNTQAAVDTYTEPEMSFGGGASIAAGPIGGTADLKDLKPVLTYTRSKGLYGGLTLDGTVIKEKPDTNAEFYGSKLTTAEILSGKVPAQNNWPAGGTQLIEVLKLAEGKDGDAKVLQEVNAEDSPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA47</accession>
    <name>A0ABR3ZA47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="76421" checksum="9946B221C86A0B82" modified="2025-10-08" version="1">MSPSAVPDWDDTPIRPPNADEQIGWAGVPLSETLGYYGVIKRPQLPTNDRLGFKPDYASVDVNNLVSQFIVPFGKSVEQQDVNAIINHIAEDGYWKDVELLTWDIRTLTGHDNISAMLTERLAVTGIKNLRVSPYIPSSLEVLGEDLSFVLFHFEFVFAHGTGIGAARLSPIAARTGSAAELADISSWKLYSIGTAIETVDGWDAENGDKMRYQKAKVQDPLGRARTYRQLREDEREGRDGFQPTVVIVGAGHTGLTMAARFKVLGIPHLVIEKEDTAGYSWGSRYASLSLHGPTFTNHLPCLPYPQWFPTFLPAQQLSKFLQLYAEVMDLNIWTKTQLDGKGAVYDEKSGQWTISVTRGDGSKHVLHPKHLMIATGISGTLPNVPQVPGMSEFEQNGGLIVHSSRHKTDPAWKGKRCLVVGAATSAHDISYELVENGCEVTMIQRSATHVMSVDKSVRTLFKPRERTNRRDGLAADLMDQSNYLKQPFPVEYELLSRGQKIARDLDADLLQSLRDVGYRLHDGYHGGGAYSMFLFDQGGFYWDTGCCKLIAEKKIGLLHSEIEHFTKDGVVFKDGTSYQADVVVFATGYMNSKSAIQALIGDEMAKKCHERWEKGNAFFVGPEGESIINYCPLPQKGLYSMFHQFAFSRFHSARLALRIKAEELGIDVTPYGNKPLGPSNTAAGRAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAI2</accession>
    <name>A0ABR3ZAI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA-binding protein VTS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VTS1</name>
        <name evidence="11" type="ORF">Sste5346_003969</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA-binding protein involved in post-transcriptional regulation through transcript degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09556">
        <property type="entry name" value="SAM_VTS1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037635">
        <property type="entry name" value="VTS1_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAM" evidence="10">
        <location>
            <begin position="524"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="198"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="496"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="596" mass="63719" checksum="BFE7C5580AACEC53" modified="2025-10-08" version="1">MAGNAHLRASADMAALSGTSPSSRIRPSSDFYGQSQPPPPPGIGELDPQDKLAQEWIADIDQYETTLEEMAAATLDQDFKDELSAIEQWFRVLSEAERTAALYALLQQTTQVQIRFFIQVLRQMGKNHPMSGVLSPANFDKDPMSNRLSDAMNKLSVDSARNSMARNSMMSVKRQSGLDPSTINAMFPDAAAAIATEKAKYTQQTGNPPVSNRNSAIDPRNSLVAPTISTPADAAAGSASLPVASNGQNPTSPWGPSSTANPAQPSVTSPGQPPMGQFSQPPPSAGGLRSPRPPMTLAPQTINADKNADLPLLSPYGGGGNWASMVNTPMVANFSQQQSGNQADMVANATAMKLAALSTVNNRVFLDDVRKYRRTRSNDAPGAPQNPLSPSAPTIQLPGGTTNVVMVNEHGQILRSEPMLAVPGQQPLGFGAHRSRPNSPGIAMQGGFGGIPFTSPQNNGFLSAYDGSGLMSNSLNLGGMNLGQLGLGGPHEGYLSDHSDIIRGRSPRGRRGSSKPPEDPTDPTLLQDIPSWLRSLRLHKYTDNLKDMQWMDLVELDDKQLEERGVNALGARRKMLKVFEQVKEAKAEGKLADPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ1</accession>
    <name>A0ABR3ZBJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_003791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000017">
        <property type="protein sequence ID" value="KAL1897939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF149">
        <property type="entry name" value="GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin N-terminal" evidence="1">
        <location>
            <begin position="35"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="206" mass="22498" checksum="6C36E859A204C675" modified="2025-10-08" version="1">MAPINIQSQDYRDLLDIIDCLPSQGLDRYVALPEIIVCGDQSSGKSSDGLCTRFATELILRRHPEASVVVSIKPYHTRSDSEKEKLLAFTATLDAENPDVGPVIEAANEAMGLVDGKVDGEDGSSSSSRHFSNDVLRIELSGPNQQYLTLVDLPGLFLSSNSKQSADEAPVVHQIVTEYMKRPRSIILAVVSNLQTKSSYEAFMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCE7</accession>
    <name>A0ABR3ZCE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5672 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_004013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000018">
        <property type="protein sequence ID" value="KAL1897705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043729">
        <property type="entry name" value="DUF5672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18922">
        <property type="entry name" value="DUF5672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5672" evidence="2">
        <location>
            <begin position="148"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="414" mass="46537" checksum="F361936AE95A40F2" modified="2025-10-08" version="1">MSESDSFLRRRGIDSLREVRFSDIKNAVSLLSMAAWSKTSRRMRLFGAFVLMFVLAIFFSDTLLSASNVNYPTIKLEYAQPQRSTFNESKVGLLIENRPFPILAPLMLHFISVVPPDWRFRFMGSIESVKKINESIAIQEQVKAGKLDLTYIPSNMSTGSQEEISRFLTTRWLYETVLQPAEWLLVFQTDSILCANSQHNLNEYLEYDWIGAPWSTHSRWGGNGGLSIRRVSAMVDVLKDQVRVDGSEPEDVWLAERLGHRPKSKVANGTVSLTFSGEMHSGEAARLENITISAASKEELEEAAREGKLVKGVDDWRAGFYEPMGYHTGGSGKYLHDQIWGSPERREHVWKYCPEVKMTLAMDAAKFVPGTCGASWKRSVDIPGMSQGIVDVGYGSEIINGIQYPVLPPGLVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD11</accession>
    <name>A0ABR3ZD11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Sste5346_004130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000019">
        <property type="protein sequence ID" value="KAL1897394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="150" mass="17198" checksum="419C5BA6791FDAE7" modified="2025-10-08" version="1">MDKSYFCLLVLLFPIVACTWLWRHHKAHKRREGQPQNVKLTRLQRHQARDAEHRRAVEEQTRLHPYWGTLPSAMPRRPTPAQLLPVYEPRPRAASVNYFGFNSNSSDSLARSMTGLPPYSPMSPPGTPVLPWIADADNDNDSEDVNLTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD42</accession>
    <name>A0ABR3ZD42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_003682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF20">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="79"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="523" mass="57388" checksum="3919CE96648F8231" modified="2025-10-08" version="1">MAESPKNEKLESPQVAEFDPEPASQGGISSWWGSGLKIGPRIGPDITGSSLESDSEDSSATILEKQLAQEDGCAIQYRTCSWQKTAALLFSEYICLAMMSFPWSYSVLGLVPGLILTVVVAAFVLYTSMVLWEFCLRHPEVRDVCDIGQMLFWNKKWAWYATAFMFILNNTFIQGLHVLVGAKYLNTMTAADNNIACRTVSFSVVMLVISWVCSLPRTFSMLSKLGTASAFFTFISVLLATIFAGIQAHPAGYDPRPSYTAADGTAAVGGNPIVTAIPVAGTTFVAALNAFMNISYTFIGQITLPSFIAEMKDPREFPKALWACTIAEIVLFSIVGAVVYAYVGNQYMTAPAFGSLEPLYKKVSFSFMIPTLIFLGVLYASVSARFIFFRIFDNSRHKNEHTVVGWGVWTAILLVTWIFAFIIAEVIPFFSDLLSLMSSLFDSFFGFIFWGVAYFRMRKVDGGLELVKQGNVRAILMAIFNVVIILIGIFFLTAGTYASVQSIVDAFNANQVGGVFTCASNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDF2</accession>
    <name>A0ABR3ZDF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CDR1_1</name>
        <name evidence="12" type="ORF">Sste5346_003588</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000016">
        <property type="protein sequence ID" value="KAL1898182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="677"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="819"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1246"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1281"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1321"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1366"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1395"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1425"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1518"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="201"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="910"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1552" mass="172776" checksum="7CD05CB1E40B5BE8" modified="2025-10-08" version="1">MAFMGTGSFGSYDHTAQTGGVPLSRRRTQDEEGNVGTEPVVLGATGVDDAGTRATSLTETGDASFAADKETGKETSPAPAGGRANDLEDDDEESEDHEVHAEMQRRNSAVQSLARQYTRQSQASAGVVGNHNVFLSSSEPDSPLNPASANFNGRAWAKAVVDMVSQNGHEFRTAGVCFQDMNVYGFGKPTDYQKDVFNVWLELAGLARRLVGGGQRRIDILRNFDGVVRKGEMLVVLGPPGAGCTTTLKSIAGEMNGIFVDDKSYFNYQGMSAKEMHTKHRGEAIYTAEVDVHFPQLSVGDTLTFAARARAPRTMPEGIHKNMFAEHLRDVVMAMFGISHTINTRVGNEYVRGVSGGERKRVTIAEAALSGAPLQCWDNSTRGLDSANAIEFCRTLRTQTELFGSTAIVSIYQAPQSAYDLFDKATVLYEGRQIYFGPTGAARQYFINLGFDCPARATTPDFLTSMTSPQERIVRAGFEGRAPRTPDEFAECWRNSAEYRALQADIEDYKTTHPINGPDAEAFRASKRAQQAKVQRAASPFTLSYTQQIRLCLWRGFKRLRGDPSLTIGALIGNFAMSLIVASVFFNLQPVTSSFYQRGALLFFACLMNAFSSALEILTLYAQRPIVEKHARYALYHPSAEAVASMLCDMPYKITNCITFNLAIYFLTNLRREPGPFFFYLLISFVTVLAMSMIFRTIASASRTLSQAMVPAALIILGLVIFTGFVIPIDYMLGWCRWMNYIDPLAYAFEALMVNEFTGRQFLCDTYVPSNKITGYGNVSGNNHVCSTVGSVTGQPYVDGDAYLNTALRYFDAHRWRNFGIIIVFIVFFFGTYMVAAELVSEKKSKGEVLVFRRGHKPASFTESHKADPESGTRVSGPAVAAANKNLDEKSGSDKESGGAGFIQRQTSVFHWQDVCYNVKIKKEDRRILDHVDGWVKPGTLTALMGVSGAGKTTLLDCLADRVSMGVITGDMFVDGHERDNSFQRKTGYVQQQDLHLQTTTVREALNFSALLRQPAHVPRAEKLAYVDEVIKLLDMQEYADAVVGVPGEGLNVEQRKRLTIGVELAAKPPLLLFVDEPTSGLDSQTSWAILDLLEKLTKSGQAILCTIHQPSAMLFQRFDRLLFLAKGGKTVYFGDIGEHSKTMISYFERQSGQRCPEDANPAEWMLEVIGAAPGTHTDVDWFQAWRKSAEYTAVRAELDRLHENPAPQPERSKADYREFAASFPDQCREVIERVFQQYWRTPSYIYSKMALCVLVAIYIGFVFFKAPLTIQGFQNQMFSIFNLLTVFGQLVQQTMPHFVIQRSLYEVRERPSKVYSWRVFMLSQIIVELPWNTLMAVLMFVCWYYPIGLNANAAAAGQTAERGALMFLLLWLFLLFTSTFTDLIIAGFETAEAGGNIANLLFSLCLIFCGVLSTPDTMPRFWIFMYRLSPFTYLVSAMLSVGVANTEVHCAANEFLNFDPPSGQTCGEYLDAYMKLAGGYLTNESATADCNFCSIKETNQALAGVLSFYSERWRNFGILWAYIIFNIFGALFIYWLTRVPKKPKTKKVKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFA9</accession>
    <name>A0ABR3ZFA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATG8</name>
        <name evidence="10" type="ORF">Sste5346_003285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000014">
        <property type="protein sequence ID" value="KAL1898874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="119" mass="13920" checksum="519F554C61DB5748" modified="2025-10-08" version="1">MRSKFKDEHPFEKRKAEAERIRQKYTDRIPVICEKIEKSEIATIDKKKYLVPADLTVGQFVYVIRKRIKLAPEKAIFIFVDETLPPTAALMSSIYEEHKDEDGFLYIQYSGENTFGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHW9</accession>
    <name>A0ABR3ZHW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">AAA ATPase afg3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AFG3</name>
        <name evidence="14" type="ORF">Sste5346_002783</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050928">
        <property type="entry name" value="ATP-dep_Zn_Metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655:SF2">
        <property type="entry name" value="AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="543"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="85"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="261"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="957"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="266"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="994" mass="108983" checksum="10BFDC7A77348B27" modified="2025-10-08" version="1">MSSTTLLRLRPSPATTTATRLALSRLSPCRQQTFVFARLHSSVSSSTKPSRCLTASTLSLSSAPLRTTLSPSAATQSALQQSLRFYSAGPTPPPSNGGRRKKKTDKPEEEESSAVPKGEENASAEQEKLAKQADRLEDGGKLGSEEQPQQQQQSQQQQEQTPTDPEASSDKASGEPPIEEMPLPPNWVRLNDEELALLSRILAYAPPSRRDSMLEVIEGIRRYGAPVELRELIAKQKDGSLSLADGMKVVKVAINMAKQFSESEDSSAANRHPGQNNSNDPANKDNQGQPNNMFNSNEPQKNSGGGNNNGNKQGGQQEGEKKGEDGKKSGPKSIFEGNDWLGWALGAAIFYPIYSLLFPGGQTTEITWQELRRNFLDRGLVERLTVQGKRVLVELNREATQSAYPDSQAASPWQQYFFSIGSVESFERRLEEAQDELQIPPSERIPVSYASEGMLGSLLMGFGPSILLIGLMYWLTRRGAGGMGGSSGIFGYGKSKAKRFNHETAVKVKFSDVAGMDEAKVEIMEFVSFLKQPERFERLGAKIPRGAILSGPPGTGKTLLAKATAGESGVPFFSVSGSEFVEMFVGVGASRVRDLFATARKSAPCIVFIDEIDAIGRSRGDGKFSSGGNDEREATLNQILTEMDGFNTSEQVVVLAGTNRPDILDKALMRPGRFDRHINIDRPTMKGRQDIFRVYLAKIVTKEDVDYLVGRLAALTPGFAGADIANAVNEAALVAARANAETVEMKHFEQAIERVVGGLERKSLVLNPQEKRTVAYHEAGHAICGWYFEYADPLLKVSIIPRGQGALGYAQYLPVGDAYLMNVKQLMDRMAMTLGGRISEELHFDTVTTGASDDFKKVTRMATTMVTEWGMSEKVGPLHFRQDDQNQFQKPFAEATAQTIDAEVRRIVDAAYKQCKDLLKARKTEIGLVAEELLLKEMLTRDDLVRLLGPRPFPEKDEFSKYFNNDGPPPFEPSNTDTELGDGPAPSPALFKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ2</accession>
    <name>A0ABR3ZHZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_002698</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="209"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="391" mass="42366" checksum="9A857E1F644A28E2" modified="2025-10-08" version="1">MNFADLKLLSREVASVDKCFINAKTSEGWVRVRSQHDFFKVCHHLNGLDYQGYILSASADNSSRSVYIWDQKKSRSSTNPSSSSRRAGAPHLSPYSKAASTLDYGHYGPGNEGVSPAEYNACYSYDSGYCSGASSSSGYPYSAEPSTQTVTAMAPDFASSQQYEGADCNSGSSWYPHYSSGSGVDYGCDYGYDHPVDCATGHGVVPQTVKVVVKNLSRHASTNELESYLLSAVGGRNMLQEDVRFPRQTSTSSSSSSSRQHAFLLFKTHSDALMAVNKLDKTKLLGLVIEARLATEMLLPIRGSPSSTSFYVPPLDNRSTTSSGDVGTVTGAATSIYDDDGCSAASGHWDGSQTKREKSHNLVVDGKSIYGHVKKAVEETKARDRKHKHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIB0</accession>
    <name>A0ABR3ZIB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Sste5346_002656</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000011">
        <property type="protein sequence ID" value="KAL1899790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="11"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="508" mass="56151" checksum="877CF9E3D0E43F4B" modified="2025-10-08" version="1">MAHLSSYNVYIVLLVAVGAYTYGFAFSVFVTSIGLDGFYDFFDLDPTSAYTASIIGAVNGLFAFGCAFGSILQGWVGDWLGRKKTIFWGSVVTAVCAGITAGSQNIAMMIVFRLLEGIGLGALICQVPLYISEVAPAHKRGMLSGLTACGFAFGYLFCAWVAYACSFAANVTLQWRLPLALASLAPVILAAVVWFVPESPRYLSWVGKNEEALAVLQKLHRDPRDPTDQRVALAEFLQISQQVAYDKQHSAGYWDMLVRVPSWRRRSLIILFLFFASQSSGILGIANYSVLIYQNLGMTGHMPLLMYGIYIICGTIPNICSIFVVDRLGRRTMLLWGFPTAGLCMLATALLQMKYNSTTNHAGNAAALFFIFFYQWFYGFFIDPTQFAYAAEIFPTVIRAKGIGLAFFSYFVGAVTYTEAASTAFREIGWRMYMVWFACSMATPFVIYFFVPETKGRTLEEVAELFGDRVVLHMTADGTDIVEKDKDKTEEVLAGGVEVATVHDEGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIT4</accession>
    <name>A0ABR3ZIT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002527</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="307"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="724" mass="79175" checksum="9CF52344280D0B40" modified="2025-10-08" version="1">MSSDMAHSRLSEIFAEEAAAAVAAAAATAAAANKHLPGPLRAPSIAPSLTYSESGDDRDEYDDTQQSSSEDEASIATPRRRRASTRLIAQNAADIQRITGESSTQLINRCCGGGCCLKAGSKAEGVQYETVPLPDNDAFRSLQLKIGDIPTSLTSVAEIPEQTAYILPLSARSTPPPTSSGTSVETPVQATAELATVEKEVTPVEVPPPAAEGQAKPAAASEPPHLVPTDSAISMGEDKDELVKAVESETMAEIKDKAAAPAAEAETEQKPVLEGLQNLAIGHEVEEMPDLDTTIQPPFFVQPHPPYHVYPARIHNARELTRPGAEKRTYHFDLDVTDYPVETKMDFRVGGAIGVSAPNDTELVDEILDLLMVPRFLRDKPALLHTTKGRWPTVWGEEKPRELVATRRDLLTWCSDVQSYPPTKGLLRLLAEYASDDNEKKVLLFLCSGEGQGVFCDFRTGPHVSLQQMLHAFPSAKPPLDKLLSILQPQMPRFYSLSNDPHESSAKEGNNARRVIEIAVTVHESSDWLNGTRTGIGSGFFERQAMKFLQARKRGEEPDLYIPMFKGLMANPLAKQFVPDGPMLLIGAGVGIAPFRGFVQRRLKTANCANKVWVLQGIRDSLVDELYSGEWGVHEDEVKRVVESRRGTGRYVQEEVRQQADLVWHVINSVDGRVFVCGSTHGMGEGVQEALIDVAMEKGNLGRDEAAKFWELKKEVGQYTAETW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJW0</accession>
    <name>A0ABR3ZJW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Choline transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_002007</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF1">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="422"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="62937" checksum="545577B058FD081A" modified="2025-10-08" version="1">MALTSDDVGLAKLGKKQEMKRRFGFWSLLGFATSELIIWEAVLSLLSLGFTNGGPAGLVYGYIISWLSSMSVYLVISELASMAPIAAGQYYWVFMLAPNGYREFASYLIGWLTSMAWISTIATDCIYGGTILQGLMILRDPSYAERAQRWQGTLFAWAMIFSAILINAIIPGSQPKFEIGTIMLHVAGFFTVVGCLWAYGEHSTSSFVFTTSINEGGWPTQGLSYLVGYVGCVSNFVGADCSVHMAEEVDRPSRNVPLAIMTSLVFNGIIGLTMMLTLLYNVGDVDSVLNSATGYPFLQVFYNALKSVPGAVALGAVTLALTWSCAIGILTTASRMSWSFARDRGAPFSDTLRKVDKRNQVPINAILVVGACSAVICLIYVGSSAAFNDVVSLNITGFYGSYFVPSAFLLYRRIKGQIKPYPGKASTSVDPEEVPEKVLAGGPAGSDADGDADIADAPEKSAITGSNKVDLATAQTSPSFADGTVAALEIIAEDHSWGWFHVPGWLGIANNIYACCYMVFVIFFSLWPSEYHPNAQTMNYSIVVTSGVLIFSLIWYFIRARKEYHGPIIDSEVAAIVVQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJX7</accession>
    <name>A0ABR3ZJX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_002245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000009">
        <property type="protein sequence ID" value="KAL1900522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="710"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="779"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="866"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="919"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="753"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="871"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="947"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="105129" checksum="3661764087F741C7" modified="2025-10-08" version="1">MDAVKFVPPGGHRACLSCSAAKAKCVFSDDAEAGDGFIDGLDFINSTTNDLAGPSHSASSASNGQEGTPAVPRCQRCERLNRDCLLPTRPRKKRRRRRHESPAPTSVRMAQLARHQGHPELQQVIRDQDLQQQQHQQQQQQHQHHLHLQQQQQYANGVTPPASVKAAPTSIPIPAAPLVPPPPPAFSLPPPPPVGSPPSVDPANLQSYAGSSSSATVIPPGGLGGSTGATPSVASSMPSGGGPGGPGAQPQDPAAPAAPTPNAHQVLIESVFNMEEREAEELLRFYRDAFSKFNPYMEPTPPDTKVADLQAQKPLVWLTIVFVTCFHDFERQNRLARAIIYYITDQVFLNSSKSLHLLQGLLIFVNWFISQNFVLPQFTNLIHTTMALITDLGLNKLEFSKTNARSPLDRYVTKTMHGPGMVAPDEGHTLEERRALAGGFILSHAMSDGILMVTPLHYTLQLEDTCRFFEAAYYEKAKASEPITAVVAADYHLAITVRFYYLISRVLQVQRDADLAGGRFLIPVRTHIENFVAELARIWGGLSREMQSDFKIQLSYSTAKIYIYELSLSVNTTPFKSHSTPSRESDDGSAPLEGDMPIQCYLAAKSFFDVYLTLPVSLYHQFPVTMITQLVHADLTLAKLTAYFRGNTRPPGVPEGVTLPAFTDVIDAVASRFQRVRTVPHPLGYTVRNIIFDAFAVRLRSFKVLDLAGRKKKKNKEKEKAAAQQQQQRGASQGHGHGQGHGHGHGGGPPAPSNVSTSTRTPPTANAVLSISNLIGNVPEAMNTEPDSGSESAGPNPYPSVEMDLEVDNINIHGDLPDRSRPFTVDEEPMMNNDDMDMMELTGSDEEEQAEWWAWFGDFQSSLMGPPKLPSTTAGSVSGTSAAGTSAAGASASVTGGSVAGGSAVGMSVAGSTAGASVSASATGTEDSYSHTGPFPGQFRRRKGPSSVGSIDSLLNNNDQEPNLNSYIQARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKD9</accession>
    <name>A0ABR3ZKD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gylcosyl hydrolase 115 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_002594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000010">
        <property type="protein sequence ID" value="KAL1900283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.520">
        <property type="entry name" value="Glycosyl hydrolase family 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031924">
        <property type="entry name" value="GH115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041437">
        <property type="entry name" value="GH115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042301">
        <property type="entry name" value="GH115_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842:SF2">
        <property type="entry name" value="GYLCOSYL HYDROLASE 115 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17829">
        <property type="entry name" value="GH115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15979">
        <property type="entry name" value="Glyco_hydro_115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gylcosyl hydrolase 115 C-terminal" evidence="2">
        <location>
            <begin position="790"/>
            <end position="966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="970" mass="105221" checksum="9E5A91D0DEADCA1D" modified="2025-10-08" version="1">MFAISSVAGESGGDFYQLADVADSITPQIYVDSNDLPGVLRVAGDLAADFGRVLGSSLNGTVVKTDWAALSAKTSGAAPQSRPAIVLGSIGASKLLDGLAESGPLTGSLSSIRGKWETYVYQVVDNPWPGQDKALIIAGSDLRGAVFGAYGVSEQIGVSPWYWWADAPPTQRTHIAIRKSSSSNNATVFGPPSVKFRGIFFNDEAPALTGWGAANFKKSQYGSAFITEFYKHAFELILRLRGNYLWPAMWSSMFYLDDAQNGPTADLYGVFMGTSHHEPMARADKEQNRFLKGSWDWKSNKAGVQAFMKEGATRSKNWSTMYTLGMRGSGDAASATLTSALLEEVIHWQQQTLTTELDRPLADIPQQWVMYKEVPGYWQNGMNVSDDVTLLWSDDNRGNIRRVPIANETSRRGGSGMYYHFDYVGDPRNYKWINTIQLQKTWEQMTLAYHRGVQNIWLVNELPTAHIMALAWDVKSFDEPASTRQWLTEWCGRQFGPAAAENASAVMITYGTLVARRKYEDLSSTPFAFDTTNYDEARRNYAAWERLAVQAQALYDDDKLVPTAAKASFFEVVLHPVLAGKTVFEIYTKAALAPKYANEHRVSTNDLAKDVQAAFATDKALKSRYHTLLNGKWNHFMDQTHLGYNNWQEPGSDSIPKVTTLGSGSASGGVLGITVQGSTSVYPTASSLTLGTITPYTPAESQRWIDIFLRNTGTVAYHIVSNATYVTVSNAQQTLSSSATDARALVSVDWSAAPSGRSAASLTVSGDNGSSSATILVPLDKTAPPADFHGHVEADGVVSIEAYHHNGAANSTYVTIPDYGRTHSGVRLPPLTASQEPGKGPVLVYPFYTFSNAASPQLTVYLSPSENSNPTHPNRYAFSIDGADDLASSSSVTVVQPVPLANAGGEPSGWSQAVIAGAYVKTNKLGSSLTPGKHVLRVWLLEPTMVVTKLVLDVGGLKSSTLGPPESVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKV5</accession>
    <name>A0ABR3ZKV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="417" mass="42176" checksum="67AEFBBBCFD314F0" modified="2025-10-08" version="1">MSGFSNVLKNGWHPDKNADFKKQVTGIWKKDDSAYDARADHVSRPLSSLRDPDSFGPPPRHVALGSEPSARGTAVSTHHTASSTGSGSYAGSHTSSHHALATPARPSLPSRPRATSSATEEDEEPQESQPYRMDTTGLNTSHLPPPPTRRDGSGISRSPVPPSSGPTKRPNAVPPGLPPRLPPRSTPSPNPPAGAGHTSTHPPPPPRQPAHPRVSPATTGNTGNTGNDTHINQDAVNRLGRAGISVPGLGIGGPATSGSAHSGQAQPTALSAINSLVATSSASTAHEPVQTVNHAPPASQLGELQARFAKMGTGGGVGGGTSRTPSRSPARLRANSGALSGAHSSADVSGSSTPALSSGAAASIAAGKKKPPPPPPAKKPGLAAVKPHAAGAGSHRTDNDDDDAPPPIPMATRPQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLC0</accession>
    <name>A0ABR3ZLC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_002040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1900977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="61648" checksum="A4F7635A9882E38C" modified="2025-10-08" version="1">MSASTLIPDWVPPQYLDMATRSPSLTAALAVGIFLFFRLLTMGRREKGLPPGPPTLPVLGNLHQIPTSGLHAKFIEWGEKFGGVFSLKMGSGTMIVLYDRQAVHDLVDKKGVIYSERPRDHVADIVTHGDSFAFMSNTPMYREQRKIAAHNLSPRVLDERAGPIQDAEITVLLRDLLDRPEAFYNHVRRTTCSVACAMVFGQRGASYESFFGHCVYDAMDSYSESLEPGANPPVDQFPFLKYLPDAVSPWRKRARRSYEAMDATWSAARAVMDQRRARGERRVCIADSVLDDPKLAGKMNDGQLNHFLGVLVEGGADTTASSILTLIACLARHPEYQRMAQVEIDALCGAPEDDTPKTARMPIWSDFAALPFVNSIVKEGIRWHGVLPLGVPHRVAKDDWYKGMLIPKDATVVIPSYAIHRAERFHYSNPTVFDPRRFVNHPRLASDYAGSPDFNKRDHYGYGAGRRICPGMHLAERTQWRAVAKLLWAFDIELPTDPKTGAAIVPDPEAYHEGIAHTPKPYSVIFKPRSPARAAAIRREAKATQVELAKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM92</accession>
    <name>A0ABR3ZM92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156">
        <property type="entry name" value="CCCH ZINGC FINGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156:SF1">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="349"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="349"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="403"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="428"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="468" mass="50540" checksum="D6C4F52B1F4A8E8E" modified="2025-10-08" version="1">MTSENQELLARISHLAGRINRHKNQQAGISSIPSSPYNKYDSSASAPASSSNTYHAPHYNRPTYAPRGRGVGGGYRVKKPAPHRNRTLVLNNSGSSSRSDGTENGGGGGDSATNSDGGSSTTWVARTDRHMQLINADVYEKDAQTRARAIEKTRAQNQQMRDARERAKLRSHFSYLARGQSTGNNSGSNTPQHYQVMVEGIPFAVAKNGSKLIKLPGASLSLPSPPRSPGSTGSTCNDDCFFEDSAHPAHPPLGDPNPASSTPKTAVVGGVKFYRSKNGNLYRHGVVKAQQQRKVAACKDFLLKGDCARGNGDCDLSHDLTPERTPFCLHFAKGNCTNPHCPYTHSQVSSGGPVCRAFGFYGYCDRGADCKERHVFECPDFSNTGVCKIKGCKLPHRERASFMRRANANDSSTGTGTGTDEDNHIDISSDDDSVNSDDVDSDEVDEFVGADGDDADLDFVNQKDYIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMG7</accession>
    <name>A0ABR3ZMG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L23A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL23A</name>
        <name evidence="5" type="ORF">Sste5346_002099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000008">
        <property type="protein sequence ID" value="KAL1901033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="139" mass="14670" checksum="59B50551FAA136D2" modified="2025-10-08" version="1">MAKLSRGAPGGKLKMTLGLPVGAIMNCCDNSGARNLYIISVKGIGARLNRLPAGGVGDMVMATVKKGKPELRKKVHPAVIVRQSKPWKRTDGVFLYFEDNAGVIVNPKGEMKGSAITGPVGKEAAELWPRIASNSGVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMQ6</accession>
    <name>A0ABR3ZMQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VPS20</name>
        <name evidence="2" type="ORF">Sste5346_001904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="74" mass="7913" checksum="C3687BA99EB54B29" modified="2025-10-08" version="1">MYEVSEMLGGSMSVADEDEVEDELAALEAELAPAQPAKVVLPNAPNTQPVAAQDPIAAEEEEEPQPERRQLVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN33</accession>
    <name>A0ABR3ZN33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">Amino-acid acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="5 15">2.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 15">Glutamate N-acetyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 15">N-acetylglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ARG2</name>
        <name evidence="18" type="ORF">Sste5346_001589</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">N-acetylglutamate synthase involved in arginine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="5 15"/>
    <dbReference type="EMBL" id="JAWCUI010000006">
        <property type="protein sequence ID" value="KAL1901884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011190">
        <property type="entry name" value="GlcNAc_Synth_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF4">
        <property type="entry name" value="AMINO-ACID ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007892">
        <property type="entry name" value="NAGS_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15 18" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="552"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="24"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR007892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1901884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="739" mass="80279" checksum="6E5A351E02E918C7" modified="2025-10-08" version="1">MVLRTAAWKQAVFAPIRTGKTCTRWKSSAAGPAAAAPKSGNSNNSSRQPATGAVSSSSSSSSDKKVDLTSLYTSISRNEKHKKSQERDFLVSVLSSSPTKRDAKKYLQTFGSDKSKDASKTATPAKQDTTQKPQPQTSSDGAYYAADSIRAVSQSPQFVQGPGSEKVKLPMDGQPHVAIVKLQDPDTIDDATLEGLAKTFVQLRALGLISVIVIGRTQPASSNGPGWFDYVTHATLRVAAAIDKYGDPVTSLVDSAVGFKDNIPAQRDQHAQLSGSAFTPGQVYVDREESLLRPLKKGDIVIIPPYAFSTTKSEARLVDTDDIVLALTRYFAGMQHQPDTSPSDASTEHSGRTGPVASVDRVIVIDPIGGTPSALRPNGAHVFLNLEEEYRSAKKAVDVMADKSMLKSTNGQPPEAVSEGHKANLDIVRNTLALLPSSSSALLTTPAEAANLVSHERGSADEADDVFGYVGSVGTRRSQNPLIHNLLTDRPVYSSSLPIGRIKPRSKRSAAAITTSVTDEPPMSQTTLLKRGMPLTIYPDPYKAPWTPPKPGEPRLRLTDTCIDLPRLVHLIEDSFNRKLDVQDYLRRVENSLAGVIIAGEYEGGAILTWERPDGLDEEMAYRTGRLVPYLDKFAVLKKSQGAGGVADIVFTAMVRDCFPEGVCWRSRKDNPVNRWYFERSRGTWKLGGVNWTMFWTTPWGATPPGGVTKGVDDQRIWDYASVCRGVEPSWADQKHILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNN7</accession>
    <name>A0ABR3ZNN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SNARE-complex protein Syntaxin-18 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_001296</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019529">
        <property type="entry name" value="Syntaxin-18_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10496">
        <property type="entry name" value="Syntaxin-18_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SNARE-complex protein Syntaxin-18 N-terminal" evidence="10">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="366" mass="40125" checksum="7831D8C783642D3E" modified="2025-10-08" version="1">MYALDLTPVFDQLLKSKEGAPTRKPRFDASQTEGFLKEAYRINEHIATLSKQLGDVRQAYLSTAPPRRSHHHHHSSHNDDSSAPTSLTDSEREDIDANAKRLLRDLNASIRGLAEAEALHQETQQALIRKQYAGPSFRFVGLGTTAKSPEQAAAEEAQTQVAAHHESILWYLRQRLQACGRAQQTMMEARLARMVVETTAASQQHALLVGATNLAPRGSGGFGGASASAAALEEEHNRGQSFAPERHGGDSGNDGAAADLTAEQIQMFEKGNQDMLKHYETTLDKVRAAEQSLVEISELQTMLVGNLEIQSAHVDQMVADSVTTAENVAKGNRELKKALDRPSTARYTFYAASSLCLFVVVWDFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPH4</accession>
    <name>A0ABR3ZPH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045713583" evidence="2">
        <location>
            <begin position="23"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="326" mass="33047" checksum="B2FD169FABF21FFC" modified="2025-10-08" version="1">MTTAKLTKLGALALLAAGPAMADDAGGCTVGDDTTLDFITRTLGHVTYTLLRPDTSKPWEEFMEQTGFAAIATETGVVTVTNTVTETASVTDTVTETTTVTAPAEKLVTVTATATATDVETIVSTSIEGITVSYVETITSYITTTSTLSALAATTPGIPVDVDKNLAKRDVTTTVTVYGGYGNPLTSTTGSSTTTVSATSTTTIYGTSDYPTGVPPMSISMSMSMPEDSSFTSLPPSTFFTEPTSSLSSSQSACSSGNGTWSTSAPSSASSSISASMTVSVSAESETAPAPSKPTATLTSGSGRAVLETTGGFVTLMAAITFALLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPH5</accession>
    <name>A0ABR3ZPH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_001819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cell membrane</location>
            <topology evidence="1 5">Lipid-anchor</topology>
            <topology evidence="1 5">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000007">
        <property type="protein sequence ID" value="KAL1901414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF8">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968843" description="1,3-beta-glucanosyltransferase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="391"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="476" mass="49925" checksum="1F6AA9A0F87CCAC5" modified="2025-10-08" version="1">MKFTTVSGALLAAAASVDAASSSSSLPPVSVVGNKFFNEDGSQFFIKGIAYQLSQDDPLIDGDQCARDVELMKTLGTNTIRVYHVDPTANHDSCMSALASAGIYTLIDLDTFDTYIMDPTMPAPTWTETQFGRYAAVMDAFASYTNVLGFFVGNEVIAVTNQSIAAPYIKAAAHDMKVYRDSKDYRKIPVGYSAADIAELRPMLQDYLTCGGNAADNIDFFSLNSYEWCDPSTFTNSGYANLEKQALNFPVPLFFSETGCNVPGPRLFEDQASILGPDMDSNWCGAIVYEWIQEANNYGLITYGDGSSSDDAPRSGTPKPMTPDFANLKNQWATLNPTGVKSADYNTKSVSTRDCPAATQGGWEVDGNVPIPTLEAAAISAGSKASGGGSSYTPATATGTGAGSKSTGGADKTSDTTSSGSGSGSNSGSSPSPSSTSSAKSSASSLSPKSLSVFNREFTVAGAALVGVMMVFTLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ42</accession>
    <name>A0ABR3ZQ42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="2">
        <location>
            <begin position="63"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="247" mass="27955" checksum="CC700E2FB0474824" modified="2025-10-08" version="1">MASTSSTATPAKMSFQGRVNAAKTPKSDINTLILDYLTMEGYPQAAANFSKEANLQPQQDKPSVETRQKIRSAIHNGKIDEAITLLNYLNPRILDEDPPLHFALLRLQLVERIRQANSNGNDFAPVVKFAQDQLAPRASMKKEFLKDLEETMVMLFFTPDKMPPTQQKLLSPDLREEVADRVNKAVLFEHNKRRDAAIRHIVKMRAWAENVARDKKLDVPDVIDLGLNNATGDSRFHDHEHEAMITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ64</accession>
    <name>A0ABR3ZQ64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase Ryh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ryh1</name>
        <name evidence="3" type="ORF">Sste5346_001283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="187" mass="20996" checksum="5FE690442B214318" modified="2025-10-08" version="1">MAQTGAGSSYNNPLKKFKYGSNEEGWCFWASRVTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDISNAKSFQNTRKWIDDVRAERGNDVIIVLVGNKTDLNDKREVTTQQGEEEAKRNNLMFVETSAKLGHNVKQLFRRIAQALPGMEGTDAAAQASSQMIDVRTTTTPSNQDGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQB5</accession>
    <name>A0ABR3ZQB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8878" checksum="4D0093AA76784113" modified="2025-10-08" version="1">MDSAGGNAARQQRSDSTGSSGSSGSFTGRRKSSGLFSSLEQQKRSDNPEQMARRASMHDQKPAQGMIGKWWSSYVYGTGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQK6</accession>
    <name>A0ABR3ZQK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_001413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046855645" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="51"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="164" mass="17170" checksum="59CC728D0C630AFD" modified="2025-10-08" version="1">MKTTATTLAGIVSAASLFATLAVASPVAPVESRQLIAMNPELLNPVLRGGFTAQCDFYQVTSHGEAYGHLQAMCNPDPGNPATEVASTLDLSLCLGNYNNNLAWGYMGGAFTSCMGCTSRMFATQYLDCDCGTVDLNDGIYVTDTGAVACYDNVGTADPVPYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQN8</accession>
    <name>A0ABR3ZQN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Sste5346_001407</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF14">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="593"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="127"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="644" mass="71608" checksum="17F6118D712EA4AB" modified="2025-10-08" version="1">MAEKIVSNDQEVVSHTEAPNKVEENGFDNGATGTKVDIAKQLAANIEGEIVNPLKNIPREQLLEDVARFRVEKGLPEDILPYLQKGALVAQNPARFESLEELDEADKQVIRNEVLHRWRHPWALYYTIILNSIAAAIQGWDQTASNGANLSFPDALGIPDSAGSACGPDANVGLCAKNGWIVGFVIAMPYITICLFSGWISDPLNHYLGRRGTIWVGAIFSVLAPFGMALSQTWGQLAASRMLLGIGMGLKEVTVPVFSAENAPTNIRGGLVMSWQVWTAFGIFLGTCANLAVGKVSDIGWRLQFGSAFIPAVPLVFGTFLCPESPRWYLKKGKYEKAWESLVRLRNSKLQAGRDLYYIHALLVQEEILVKEAGLDVNSGMFTRFIELFTIPRVRRATWASGVVMIAQQMCGINVISFYSTSIFAESGISAYTALWASFGFGLINFIFAWPAVFTMDTWGRRSLLLFTFPNMFWTLLTAGLCYLINDKNARIAAVATFVYLFAAFYSPGEGPVPFMYSAEVFPLSHREIGMSWAVATNNFWASILSLTLPRMLSVMQPVGVFGFYAGMNLVALAMIFVAVPETKQKSLEELDYIFAVPYRVFAKYQVGTVLPWWIKRWIFWQRTAKCPELYHDANDEPQGENTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQU8</accession>
    <name>A0ABR3ZQU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acid phosphatase pho5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PHO5_2</name>
        <name evidence="10" type="ORF">Sste5346_001059</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000004">
        <property type="protein sequence ID" value="KAL1902617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="61"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="573" mass="61552" checksum="EFF6A5D7FEE62732" modified="2025-10-08" version="1">MADYEAPAVSAAAVAQKTSGGNAAYHNFHNDFVHVQDPNERRRLALAEIDKAPFGWYHVRAIVVAGVGFFTDSYDIFAVSLLTIMLGIVYFPGVGTMPTKSDTAIKLATSAGTVVGQLGFGTAADLLGRKRMYGLELIVIIFATLAQALSSNSPSVNIIGVIIFWRVLMGIGIGGDYPLSSIITSEFATTKWRGAMMGAVFAMQGLGQLTAAFVMLFVTLGFKESLSTSTKVSNCTGVCAVAVDKMWRTLIGFGAVPGCIALYYRLTIPETPRYTFDVARDVEKADEDVKAYISGKHGDGVVDEVARATNKKANAEQLAVGKASWRDFNRHYSQWKNAKVLIGTALSWCFLDIAYYGLSLNNASILNIIGYSTSGTHSTYEYLYNTAIGNLIIVLAGAVPGYWFAVATIDTVGRKPLQLGGFAILTVLFIGMGFGYKHLSSGGLLAIYVLAQFFFNFGPNTTTFIVPGECFPTRYRSTSHGISAASGKIGSIIGQGAIAPLRTRGSTPTSSAPWLDHVLEIYALFMLLGCFSTLLIPETKRKTLEELNGEDQDYSPGPSPVIEANGGVLESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRF4</accession>
    <name>A0ABR3ZRF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Nuclear polyadenylated RNA-binding protein Nab2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Sste5346_000684</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055046">
        <property type="entry name" value="Nab2-like_Znf-CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049017">
        <property type="entry name" value="Nab2_Znf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22683">
        <property type="entry name" value="Nab2-like_zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21803">
        <property type="entry name" value="Nab2-zf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nab2 type CCCH zinc finger 4" evidence="10">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Nab2-like CCCH zinc finger" evidence="11">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="213"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="494"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="506"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="59084" checksum="222735BC33B1D3D9" modified="2025-10-08" version="1">MPVEIAMQTPLAEALQREVQKKLVENSWAPSDDSDNTMAEYIILMLVNGRQEDDISSELARDLLNLDPEDNSAREFSKWLFDTVDTQNAIINGPPVAQAPPVQDNGDQDMDMDLTGADNAGDINAPTGPKAMRSGSGAGGFRGGRDKRVMGQINRAMDRSNDSVLHRVRGQGAGINTHARGGPHGRGGMGGFGNGRQQRNMNGRQAASFNHALANSGMGGGQPGMPWAGQPGQPGQPGQQGLPGQQGMQAGPMDVYAMLEQQSRMMMQMQQQMQMQQNMMQNNNNRRGGMNNRGRPLADRVQRPHQNNKNFRNGQQDISLSDAGDDTQKKDPAADGESLTLEDFDMASETTRPETSSVAETMCKFNLNCANENCKFAHQSPAAPPGITVNVHEVCSFGAACKNKKCTARHPSPAARLAHQSEQDCKFYPNCTNPHCQFRHPAMPLCRNGADCSVRGCKFTHIQTMCKFRPCTNRYCTFKHEEGQRGTFPDKVWTADGSNGGSTNGGEKEHISERKFVDESAPEETILPGVDKDMTTEEAVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRN7</accession>
    <name>A0ABR3ZRN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <shortName evidence="5">AS</shortName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aryl-sulfate sulphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Sste5346_000718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aryl sulfate + H2O = a phenol + sulfate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17261"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:33853"/>
            <dbReference type="ChEBI" id="CHEBI:140317"/>
            <dbReference type="EC" id="3.1.6.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000003">
        <property type="protein sequence ID" value="KAL1902807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012083">
        <property type="entry name" value="Arylsulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000972">
        <property type="entry name" value="Arylsulf_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047404620" description="Arylsulfatase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="7">
        <location>
            <begin position="60"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="625" mass="69886" checksum="381EFA389D1B24DE" modified="2025-10-08" version="1">MQLTLATLLAAATSVAASGGAIKNGGAASHHGQNRLGNFGSDVLEEIVDKHHQHGTGKQPNIVFIITDDQDLHMNSLDYLPYVKKHLRDQGTTFRRHFCTTAVCCPSRVSLWTGKQAHNTNVTDVNPPHGGYPKFVSQGLNENYLPVWLQEAGYDTYYTGKLFNAHTVENYKAPKAKGWTQNDFLLDPFTYQYLNASYQRNDEPPRSYEGEYTVDVLADKAFGFLEDAAANLKSDGTPFFLGIAPVAPHSNVEIDHIQSDIDDIIAAKFTPPIAAKRHEHLFADLKVPRTPHFNPEEPSGVSWVRELKRQSVENIEYNDHFYRQRLRALQSIDELVDGLFARLDRLGLAEDTYVFYTTDNGFHIGQHRLQPGKECGFEEDINIPLIVRGPGIPGGRVSQAVTTHVDLAPTLLKLARAPARADFDGEPIPLTAHELDVAAVDDGSGRHEHVTVEFWGFAASEGDFGYSDDSRVVTNNTYKAVRIIGRSYNLYYSVYCNNEHELYNLDTDPYQLHNLLGSSANGNTPAHLLDHPLAKVVARLDSLLFVLKSCKGRACVRPWDVLHPDGDVRNLREALSAEFDTFYEVEQKRVSYSSCEAGYFVDAEGPQFELDGVAYRHGAKWHEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZS28</accession>
    <name>A0ABR3ZS28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09271">
        <property type="entry name" value="RNase_H2-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204">
        <property type="entry name" value="OS02G0168900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204:SF1">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="162" mass="17905" checksum="60300C34CC78796D" modified="2025-10-08" version="1">MTQPILEITADTAAAKPAQATPHLLPCRVHHSGPVGQADDFWRPEEKNGKSTAYFRGRKLHGQPVKLPADYRGVVGVRRDSPREQARANNTSAPEEVVDVDATAAEQEAQRQRLDTGSLSVLAEFDEVVVWGHQSTADATTDPYVRSMDEWVSLSEKIHSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSC7</accession>
    <name>A0ABR3ZSC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corticosteroid-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_001384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000005">
        <property type="protein sequence ID" value="KAL1902404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="43264" checksum="83BE220C46024F24" modified="2025-10-08" version="1">MDQLRPRLESAWATVQDRVSQLRRNRRDHLVHHVGLGYLLAVPVLLAIATALVLFVHSDVNVAMIFSQCHARARLPILSRIPVLGTPSCFLVSFFQEALARTSNRAFATMSVVLSFIGSLLTVSTVEAARICNGPSVLIAYPTGPWLVFNLVGGAMVWELLIIPAFFRRSKEIIKSADGAAGGDNGEGAANPSTRPDSRHLAVVSEVVAIPVAVALGYVVPSLVMLVTDKPVAIAVWLFFPVYVSLIRQGVRFAIRSVGQHRPGRTLHLESHKPALLAVYAVPILCSVLSHGLVLWGFLTNQPDDRQELTRSTLRFIEIDLFFIVLTVLYWILVEAGWRVVGVVLGASLLLGPGAGLCIGWIYREHQLGFVDDDEHNVAGDEGEGAAAPDEQTPLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSF5</accession>
    <name>A0ABR3ZSF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LSM1</name>
        <name evidence="9" type="ORF">Sste5346_000254</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="8">
        <location>
            <begin position="37"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1903625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="183" mass="19855" checksum="42A775FF836B1FCA" modified="2025-10-08" version="1">MENLSISEPPPQMGPPQMGGPPRPPPQQPQLPAQMFTTAAQLLDLTDKKLIVVLRDGRKVLGVLRTWDQFANLILQNAVERTFLPPGAFEASAAPESAAQGRGLYADIPRGTYLVRGENVLLLGEIDLDRDDEPPPGHDKIDADVMAELAKTKKAADKVVEKARVKKLSGLGFEGENMGEILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZSK4</accession>
    <name>A0ABR3ZSK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LSK1</name>
        <name evidence="13" type="ORF">Sste5346_000462</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWCUI010000002">
        <property type="protein sequence ID" value="KAL1903177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="347"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="700"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="769"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="726"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1903177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="814" mass="89578" checksum="42CF6BACEBE92E3E" modified="2025-10-08" version="1">MAARGGGYRGGAGHGPYSVKNPQQQQQYNYQSPHHQQQQRDQRYSHPPTHPHNQSGHGTPNSSFHGSAPPQSPYGGSQGWGPGHQQISPQGQYPPQSQQPHNNYSPNGTPLGPAAFHQANPPPFGTPSAPRSHYAQGRGGHRNSVGHGGGNGNYNNGQNANSMSVSPHPGNHNRHHHPSHQHSSHGPSHHEGDDVPMQDSDRQSGADDQMPPPSSRQPPTGPQGSKFSFAFKAASKPTVTAPKAEIAQKLSSAAPRQPQQQQSPHQGQQQQQQQQSPRQDRPPRNAPTEPASARARSEQQQRQRAEQQQSKQGPRYRKVKQIIRHPKSRPTLPDDLAASDSVYYRKPGNESVVGSGTYGKVFKAVHVYTKKLVALKRIRMEGEREGLPVTAIREIKLLQSLKHINVVELQEVMVEKNDCFMVFEYLSHDLNGLLNHPTFKLDDGQKKHMALQLFQGLDYLHRRGVLHRDIKAANILVSSDGILKLADFGLARFFAKRHQLDYSNRVITIWYRPPELLLGETQYGPAVDIWSAACVMMEIFTQAPIFPGNGGEISQLSKIYNMLGTPSKSDWPGLTEMPWFELMRPTYKLPNVFADTYKHRVTPAAFDILAAMFRYNPAKRPSAAEVLEHVYFTQEEPPARQTVELADIGGDWHEFESKALRRQNERNAKEARKAAAAIATSSPGKVNSAIAAVAGAIEASDNNQEKKKRPPPATEADGNSEVGNIEQREAKRQHIEEAKPRDGVTEVTLPVAKAEAASVIVAAISEATATSMPIPDVPTQPKQTPAFPPEGKGKPEIPAQPAPQPDTTKDMPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTV9</accession>
    <name>A0ABR3ZTV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">DNA repair protein rad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">RAD2</name>
        <name evidence="16" type="ORF">Sste5346_000109</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001044">
        <property type="entry name" value="XPG/Rad2_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00066">
        <property type="entry name" value="XRODRMPGMNTG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="15">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="14">
        <location>
            <begin position="975"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="456"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="560"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="728"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="873"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1219"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="931"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="626"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="734"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="760"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="787"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="876"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1298"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1328"/>
            <end position="1340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1903482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1340" mass="148166" checksum="617120578FBAAC8E" modified="2025-10-08" version="1">MGVNGLWQVLQPCARPTNLATLNRKRLAVDASIWIYQFLKAVRDKEGNALRNSHVVGFFRRICKLLWFGILPVFVFDGGAPTLKRATLQARRRRREGRRDDAVRTAGKLLAVQMQRFAEEEEGKRKKRELATQQQQEGGPSEVALDDSGVVDGEVLPSADKIVYAEESHMTQQERLRSRKFTKQDAYHLPELEHGSIEGMGRAEDPRIMSIEELESYARNFHAGEDINLYDFSKIDFNGEFFKSLPPPDRYNILNAARIRSRLRLGLSKEQLDTMFPDRMAFSRFQIERVRERNHLTQRLMLEVGMTGLDLTIGVNGRVAGERGREYILVKNDGAEGGWALGVVSREKDRGEVHKPIDVDALTFSYQGDNDGAEEEEEEDMEFEDVPIEGLNRLPKLASRPAAASSGVHGEEDVEDDSLFVQSYEPQEEPQQAEDALEADEDEDLNRAIAMSLQNQHGVSASDGEEGHNEEADDTDRPAPEWQQKAAETARPIFGSTGQMVAHVVNNRSNAAVSASVTAATKARETPTLNDLADDDSSDSELDIRAAMAKAAKKKKTVLGVEKAAPSRPIQPQTKNAFDGPLPFEKLNWQTSIFEKKPTAAAPQPPSTAAKPKPSFAAQAKAADMASPFATSTKASAATTAAAIAAANAAESAAFEVDSEDEFGGGFEREPTNPVSNAGRSEDVGEEEDADMDGWLEKPVDDNAPRPLPPWMSHDTDIRSAMRQQQVYNDEINAEDREAAEEEAKIWQHREEKRVVEIDSSSDEGSDIEVLDAPPPPKQQTLPKQPSPEKDAIVVEDEPAKGEASQPIVEEPITAEAEAAPDETEQPVTETRSSSPEVEFEDVKIPEQPTIFEEEQVVAEEGEPVMEPILQIGEVEAPKEEEKPDDGLFTGEGGGEAEDAYEISDPEDEELLVQMAEEVEEHARFASTLNNNTTTDAQQAYEQELKALRNQQKKDRRDADEVTQVMVSECQALLRLFGIPYITAPMEAEAQCAELVSLGLVDGIVTDDSDTFLFGGTRVYKNMFNGNKFVECYIGADLEREMSLSREKLIAIAQLLGSDYTDGLPGVGPVTAMEIISEFPGADGLEQFRAWWQDVQSHNRPKEADADSAFRRKFRKSQATKLFLPVGFPSPAVVDAYLQPEVDRSAEPFQWGVPDLDGLRSFLMSTIGWSQERTDEVLVPVIRDMNRRETEGTQSNITRFFSGTVGAGARLTEAQVREQQEKQQRLQQQQLANIPEEYAPRHAPRNKNTASSRRLAAAVSKLKASTTPAEAAASVMRASTPKASASRKRKGRASTAAIEEDNEDVMDEDGDAEVGGEDEDEEYSAPRTTRRRGGKKTKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTZ0</accession>
    <name>A0ABR3ZTZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="829"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="726"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="835"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="921"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="1203" mass="127615" checksum="7CF4C5BB0BDC527A" modified="2025-10-08" version="1">MEALLREAGEGLGGRGGFGGDDNTCRSVEELKSRISALFVGKVSDTHAEHVSVSFGIPADVVLNLGEATSFNQNDNTTPDGAANAANNDPEVATVRRGAMLGGVVRNFVTVREVVMSQPEANPLLQRAVAAFLIIQVRQADGSTYAAQEPAKATQGWTVPYACQNSMACWHLAHKMSRVVGMSVLEDMQDPLILSRPAYDCRGVVMISFSRFSRSVVVKYEHTNFHRTVSQLAALFPPPRPPSPIALPLLAPGSMNKRQKTTTADGAPKRKRPKKAPAAAAAANGTKGPAGAEGAVAGAVEGTATADGVVPEGGIPAAPEQELTASEKPKRPRKPRKPAEKKKKKGETGETAGADDNAAGASGSTQGASAIASAAADMMMDLGIDVGNDADLSENQVAEALLRHLNEYPEDNIETAAAMMDALVEHSGASDPNWQLARESATSIAVADASTTDNTLATTTATAGQASTTDTSGTTTEVRDPPYKKVTEAEVSTLRKLTAIKLLTSRNVDPATLTHDQFCTFANQAPALQKESLELLAHYGAERLAIVPAEKNANKTQSPSPTPTAAAATTTAPAATATPTPATTAVPPATTATATATSSTPSKKTAARKPAAKKNPTKDSGAAESTTAPPTTGTTLPGLRETTSTSSSWQAPQHQTAVPLPQTATPMPAAEPTPQRRKSTTSRARRSTSAADVTQTPTQTYVTPTQVSSVPLPLTAYPQETVSATASASVAEKPANASAKKPRASRKKKDPTLAPAAEPSPTITQATNVQTAAYNTGTQDQQSNSYYNNYQQTTQQQQYGHGSNNSNTPRSQQASVLSPPVINAQQATSSLSAYNSRSTTSYNPTTNTTTNQTTDTSTGYNQYGGYGRSNSGISASGTAAVVTTTATNNAGQAATANTQIAFDNYLGDYDTRRTDSPVYNTSQWPAPSTSTATTADQSAYSTTTTQNHHQQPQQSQQQQQRTTTPEAYDSLPRPAEMSGLSAMPTESLLANLNQQQQPGRRTPTSNVTYAHLLQRQQQQQQQQQQQQSHQRQQSAPPQPLPQHQSAQHRQDTAAQQAAWSNYSTTTATQHQQHQHQKNHTHSPVAAYGTQQANNNNAGSNNTAATSRMATRASSGAANNTSYGHTANTGGYQQPQQAAQRSMRSQQPQQQYYQQQQQQPHQQQQQQPHQQQHHQTRSNMDRGAYGGNQVMTEDLYEMLRRTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZTZ8</accession>
    <name>A0ABR3ZTZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="821" mass="89695" checksum="02F4B9F00109CF1A" modified="2025-10-08" version="1">MHCTAATTTTSDGPSTQEMDGTKTLGFKYRGYYQSSIRPGAKSSSSPSIDRDWAAVAKSTPSEFHHLYESIFRAVDALLRATTNTIESPRKSNSLLAMCLRKVPQFIEICEEEEREEAEKEGTMQLPSSSVSLGIYSDLETLGSEASGWKHLRVVVRQHGIDTLKSACAEGLLHETFVHLLVRLCTHLKAHDEAESLTSSLFDSYISTVPKGQYIYEAPSDLSVDLSGCSGPLASLGMLLQYAEETGRTSAALRQITELLSIGHLPASWLSSQPFVGLWHRVVRLLSSRGSPVCEEGVLLEFVATAIAKLVHSRPDDDISNISTRNISKSSNMTRDPLSASSSYHTIISILGSICAVGILQQEATFESGNFEPISSPAAIERLVAIVQRALSEVSRKIKVRKGQHKIEAAAHCYPRQYLLMLALCLLHSSQETHAENVESRDSSTFNDTAFQYLIESADSSQRGRLYDATVAFVTSVAENCGRGSEPTFSGMPVSQTYLLKLSAQAAVYLNSGSENSSSGVLTSRLQTDAAFLLASRTNDIHDLVFAESISRNSVQKEEHRLPPSSSPTSTCMGALSPLSSKTRPPPPTALFDGYLWEEGISEWVVSTPHAPSTRAAPKPKPARKSELVVIIDSMPPPESAVSDTKQRATRSGRLSLPTYFPTSSSSPRDKSDMDDAGSVFDHDSGNDTPPSPRTPGSQSELPSYSRPKRSRHFDAVSPAWESKPRLRTTRSLLNLVSDDEDENDQEDGDDNNEMEEAFDRRRETPRLPLSGHPSKAKNARRRSESTGITLKGRMVAVRRTSFQVANDGIDLASSDDELCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZU09</accession>
    <name>A0ABR3ZU09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c oxidase subunit 5B, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cox5</name>
        <name evidence="13" type="ORF">Sste5346_000296</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 5346</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00922">
        <property type="entry name" value="Cyt_c_Oxidase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707:SF10">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1903667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="176" mass="19367" checksum="90B122B009DA14EA" modified="2025-10-08" version="1">MYRVRPTTLVRGTTLAQRAVQQPQIASVARRAATTHAISNPTLANIEKRWEGLPLQEQADLWMALRDRMKGSWKELTLQEKKAAYWIAFGPHGPRSLPPPGEGKKVALYTAIGVGASLLLFAGLRLFAGPAPHTMNREWQEAANERLLEQKSDPFTGVASEGYKGKGQVQSPPKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZUE2</accession>
    <name>A0ABR3ZUE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">37S ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_000246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000001">
        <property type="protein sequence ID" value="KAL1903617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23703">
        <property type="entry name" value="mS26_PET12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058940">
        <property type="entry name" value="mS26_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26163">
        <property type="entry name" value="mS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1903617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="39118" checksum="E66FCC5BD3D5849C" modified="2025-10-08" version="1">MPLRPTVRPGLLGRPASFCSTLVLRPFSNGTNLASNKIARAPAKPSGGDDIQTALELSVPPDSPRYVRFPTPPQSDEQPRPVVKGHLPVPRNIFRKDYIPGRRKDNEDQWVKKTDIERFSANATPVAKAVQNGEAPWNEYQAMRRRLAENRRQGLQAGLRGLLQRQVEKEHRAKARSTNLANRNRRLALYTPERRDEILTRSSVRESTAKNTTVIRDPLRHEKLAASAERTAALAQQRKEERRDALMELYQAAGKFIVDEEELEKRVSELFRPDYFKEEGYSYGTVNAENIWDVVGKPNSVRELMQGITRTETKLFDAKRSELDRTTKRQKLVAEALTGGKMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFM9</accession>
    <name>A0ABR3YFM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Sste5346_010439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 5346</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWCUI010000147">
        <property type="protein sequence ID" value="KAL1887108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF2">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="554" mass="60236" checksum="6507E637416AF025" modified="2025-10-08" version="1">MFYTTKPCKAGTFSSVLPSFASVERVDTVAANGTYGEGAADLGFPSNATLLPPLCAVIVAVHNGSSNYRLALFLPTAANWNGRIMTIGSYSFAGGINWPNMGEAPHYGFATLATDGGHNSSQSDLDWAPTTLEKLEDWGYRALHGTVGLGKTLTSAYYNNARIAYSYYSGCSTGGRQGLKEIQISPESFDGTLVGAPAWDTSRLMPWLTRIGAANLPDDGPNHIDLPEFATLAAAALAQCDHLDGHNDSIISRPEACVLDWAPITCGNPAVPVGGSCLTPAQVKTAQYLYADAFTASGDFIQSGYSLGSEDLWYVYLAFGDASDFDTRYERFWLYNDTNWNWTQYSDQVFYDSLKLNLGNASADHYDISAYRDRGGKVLLYQGLADGVIMPRMTTYYYNQTIEAMNLRLATTVSSKEDYHRHHKKDGHHNDARPPIQDFFRYFQVPGMQHCFASPQEVAAPWMFAAPGQATLLSQGYNFGAGWGVPNQPASAAHDAVLALMAWVENATAPTSLVASVWNADGTVNRTRPLCVYPQEAVYGGKGSVNLAANWQCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGR6</accession>
    <name>A0ABR3YGR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_010140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000116">
        <property type="protein sequence ID" value="KAL1887529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF2">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="148"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="441" mass="49588" checksum="42FA6AA87977B10F" modified="2025-10-08" version="1">MGSVPKVKRYVLVGTGVRSAFYYESILKDFKESAKLCAICDTNTTRMNAINDHIEEISGSRVPTYKAEDFDKMVKEQEADVVIVTTIDRVHHIYCIRAMELGCDAITEKPMTIDAEKLQLMIDAEKRTGKHIRVLFNYRYAPHHTKVRELIASGVIGDVTTVHMDWILDCAHGSDFMRRWHRDKANSGGIQMHKSIHHFDLVHFWLGTEPETVYCVGDLRFYGKDNAEARGEKNLGERYHNNEAAKSDPFAFDIGASPRLKKLYLDAEHEDGYIRDRNCFAEGITIEDTLSMIVTYKNRATMTYNTYAFAPWEGYRCVFNGTKGRLEINVFETGYSAAGDPIASKVIEQQRDYVQGGVDETKIVVYPLFAEPYAVEVEKGEGGHGGGDPVLLRDVLVGDKEDEFKRAAFIRDGGNAVLVGVGANISMETGAAVKIQDLVKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHF6</accession>
    <name>A0ABR3YHF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Sste5346_010320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 5346</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000132">
        <property type="protein sequence ID" value="KAL1887263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540134" description="FAD-binding PCMH-type domain-containing protein" evidence="7">
        <location>
            <begin position="26"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="64"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="531" mass="56779" checksum="C8816971C8AAD57F" modified="2025-10-08" version="1" fragment="single">MGTTRVVAASLWLLQLLGQAQLSIASPLDVNAALDDCLKTAGVPTDALGTADWSQDVAPFNLRLNYTPIAISVPTSIKHIQDAVSCAAKLGVKANPKCGGHSYASFGLGGEDGHLILEMDRMDLVVLDNSTGIATIQGGARLGHIAAELYAQGKRDFSHGTCPGVGVGGHVLHGGFGVSSHTQGLALDFIVGLKVVLSNSTVVDCSETENPDLFWALRGAGASYGVVAEFKFRTFVVPEVVTYYSAAINWKQDKAADGLKAFQEFAENGMPSELNLRMFITKDFANFEGLYWGNKTGLQAAIAPLLNKTGAKLVLAQQGTWLDQAEHFGNGMDLNQTYPYNMHETFYSSSLYTNKLTDDQVSAFVNYWYGTGKAIKRDWYAQIDVHGGKNNAISKVAPNATSYAHRDFLLMTSFYDRVDTGAYPADGFSFLDNFTANITGSLKPAQWGQYVNYPDPRLSQAAAQNRYWGMHLDRLQGLKAGVDPNNVFHYPQGILPATTAVAATSSVSASASASAVPPSATAPPGAPTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHT2</accession>
    <name>A0ABR3YHT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Urea active transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DUR3</name>
        <name evidence="10" type="ORF">Sste5346_009948</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 5346</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="606"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="648"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="661"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="692" mass="73657" checksum="337146C152CA31A0" modified="2025-10-08" version="1">MVAPALDQGVGYGVVLGLGLAFALGMILVTFILKRYNAEQQTSEMFTTAGRTVKSGLVGSAVVSSWTWAATLLQSTAVCYRYGVSGPFWYASGATVQVLLFATLAIELKRRAPNAHTFLEIIKARYGTMAHMVFLVFGLATNILVSLMLIIGGSATVNALTGMHTIAAIYLLPLGVVAYTLVGGLKATILTDWIHTFILLIILIIFALTTYASSDLLGSPSAVYDLLVKAAADHPIDGNADGSYLTMRSKQGAIFFVINIAGNFATIFNDNGYWNKAIAASPVHALPGYIMGGLSWFAIPFLASTTLGLAALALESNPVFPTFPNRMSEAEVSAGLVLPYAAVALLGKGGAAATLLIVFMAVTSATSSELIAVSSIFTYDIYRTYINPAASGRRLVWMSHCMVVGYALFIASFSVGLWYAGISMGYLYLMMGVIVSSAVLPVTLTLTWSGQNKWAASLTPVVGLALALVAWLVTAKKQCGVLDVDCTGSNEPMLAGNVVALLSPLVLIPVFTLIFGLDKYDWKSMMAIRQGDDADASNPDVDVDVEESVPAPSVPAVSGPEFEEEQKKLLRAGKISKASTTFLAISFLVLWPMPMYGSGYVFSKPFFTGWVTVGIIWIFLSLCAVGIYPVFEGRRTLVHTFKSIGRDLSGKGPGKRRTTIEAEAVEGAGASGYATPTEKKEPHTGETLVSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI09</accession>
    <name>A0ABR3YI09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Sste5346_009964</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000107">
        <property type="protein sequence ID" value="KAL1887852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831488" description="Beta-lactamase-related domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="101"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="409"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="58527" checksum="8ECBE9BEE367CC02" modified="2025-10-08" version="1">MQHQTSVAALLMGLVAVSSAQDLPYQPCPLIRAYYPVPSINKSSSAIQKATTTFTGLFDNLVKTGCSDSFGCISPNTTSFSLAIYSIADAGDDDDFIFFDYSHTVPSLSNNKTVGLDTIFPTGTLTQVFTVYAWLIQMGDGYWEQPITSFLPELSEANSSSDSILVHWDDVSIGSLAGQMSGIVRDSYACQLGNECNYQDFITKIGASTPYALPDTTPIISNAAFQLLAFAIERSGKAKCNATSFEAILSTSFLQPLNMTNSGLLSPSSESQVFGGDFHSPGIGEPAGLSLVSTTRDLARAGRAMMKSELISASATRRWLQPIADTSNLRNGVGRPWEIYHAGQYANSTVLDVFTKNGYAGAYASYFGLSPDLGAGFAILSHDTSGTAADLNAYADIVSLALLDLEALAAAEAATYYSGNYTSRSGNGDTAVIRSPSDGYGFVVADLVVNGIDLRNQTAFAANIELENLDFRIYPSNVIQGTKHLFVAVFQDKTAPVDADTPTCITWQEVGSLGQNIADQFVFDTENAAGLAQSLSVVGRQSTLVRETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIJ7</accession>
    <name>A0ABR3YIJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000103">
        <property type="protein sequence ID" value="KAL1887969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="57"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="293" mass="32037" checksum="1E4817DB0C797729" modified="2025-10-08" version="1">MSTTMTETAPAKAVQLVAESAPVADVDPLNAMAHQGKGLPGVPSFATHEETRKWQLQHMAAAFRVFGREGYCEGISGHISVRDPEHHDQFWINPLGVHFSMMRASDMICVNLAGETVGGNTVGSINAAGFQIHSAVHRARPDVHAICHTHSIHGRAYSSFGKPLEMLNQDVCYFHNAHTVYDQYGGIANEADEGARIAASLGTNNKAAILLNHGLLTVGQTVDEAAFLFCLMERSCRVQMLADAASVAGKPKRIVSDEEAAYNFCMASTPDCLFVEFQPYYRYEEYVSPDFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ60</accession>
    <name>A0ABR3YJ60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CMW 5346</strain>
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    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="KAL1888194.1"/>
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</entry>
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
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                <person name="Li W."/>
                <person name="Munsamy K."/>
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                <person name="Sonnekus B."/>
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                <person name="Duong T.A."/>
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
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                <person name="Spraker J."/>
                <person name="Barnes I."/>
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                <person name="Li W."/>
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                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
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                <person name="Duong T.A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
    <sequence length="2237" mass="246852" checksum="A401E2B4A1B6E80A" modified="2025-10-08" version="1">MDGTKQHVHASGNGAATATATMTTTTTTTAASTPPAAPAPTGVEDGSGVGAVAGVGIGNGTARTSTAVSTMTLPWNPTNVTDVNMLGNFQLAAGDQNKPVKVHIHLKDNGHGTIFDDNGTVSSSNSTDAALLPLPTECQPKCTLKKAVDLPVYSIRSFEEVERESISLATVAANSSSTSMKEASLTSTPPVSSPPVSVTKTITTPVLVMETVTMTVTDSKGQRETITKMAVRLTDVVKTITTKIPATKTPVTKTTGAVLNTETATSTRAATTTATAKMDSKKAPRKDSKDSKKNSKAEKKPDAKANGAKTTATTTATGTQTTLASTTSLKSTKSAKPKPKTTPKVKEKKYEFTSEDMVDYLNFLVDKHHLNPDMDVQINNIEHVYDKKTYNNPPNFPDAVFPVDQDTPSLTTVDQHLVNEGHFQRIHAPGRKALRDQMAKDSLQDLNDFGEPYAPGEHKNLSKQLAHDLELLRSMETQMKDAHDWGLQAETSRASVARRQALKVARAFRRLKIGPEHHDAELLQNNTIVYLTFDDPTEAYQLVKPGYVEICEPPTLDEMGMCMDENSTSGSKAASATGIFKAPGVNPGVAQPVQLPIQFPDQVPGQIPPQSPPQFPPQLPAQFPPPQFPAEAPGTSPNDGLGGLLAELAKTMNQMQNDQLKIASAVEGLQHEQAHMGDETGDKDKDTHKSKKPQSPQKSKHQRRSMDDLENIEESGEQQQEDEKADDAQTSQEAGEKETSLDEVSTTETTSPTGASPTGVSPSGANSTPFEQTSTTSDSPVDSPVVYHYESDRGPGYVLLVPEEHGQNHTDKQEPVRLSTTADIHLNGTGPVRLHFYENNTGFGVSQKTEKGWTDEERVFEFVQELRVYHGDAFYSIWNLGKNITYHSPPVKKNGTDAVVHDDYKKTGAGYKLKKQLSPPSSPSIKRPPRASPMPKLPKGAVRLPVSGRGVRPNTRDPLGIFNGTYNGTLPGGTVPYGQPLKRYKNLPPDLPTVRPGAFDASGLALAVTTTYVKLHNNDFAGIDDLARIFTDGKGHSNGAFLLMILHRPRWNQMEEISGLLAQHGVFFDIIEDQGHMNEGVGGGPLDVHPLPIVPDADSIRYSNALQWLKIYDFTNFGSDRPYKNQTEPADKKDDKKDGKKDGKKDGKKDDKKDDKKDDKKDDKKDDKKDDEKPPERYPEWHLTTYGLIDDDVFIPDMARMISKLREHGGLVATGDTSHATSSVSSQPQWYNRNMYLGFPSDPWSDWTFHNGSTLYDQYAWEWWTFHRMTSTFGLDDRFINNDTDSLLPSTFGGGAVFMAADLAHRVAGLPCLRSSLGSNTINTVYKANRAAFNRNEHPEASWDEQLFRCVRFQIPDAPLRLVPSFYSPTDVARYGKKWETGADNSKFARSLARMSQYNGGTHPMVMHNQRTWHTFDAGAASQISDLCGADCYLQRFDFGDGWILTNGHSLTHYEGLKIRHLERHDEIDGLGKESDFAGTRLGERYHVHQDQRLYLKTMGIFLEDPARPRDPVAIEWTGHKRTYKMLETTVLQDGNVVQVYARRAATGLRDFNAHGGRESFETNHRRLAAPNSVRGGLDGSFDDEATEEAAPGRDELIVLINKAPGKKGPLLYRHNNTGHSYHYHPGLSLLSVLIVVSVIAGILEVVNYYSLSHEVLAEVLEDHPRMHFLLHRPLSSASTQVVGFLACNGVLNAVRESPLAEKVWEWYGPLQHKYSPIISPAVFKAMCRALLADVAGTTEKFDAQVDTFLDTLVENLAVVRMGYRIKRRCVSGSRVVKHHAMWLGRASFGPIKWFFVGIVRGLVHFDENGVAAFQPRDKGAFGWVRSISRGVRHLLVFVRLRDSVGADWTDEEQARLLGDELPFSSAPLATDSEEYAAASTSPASEEIFHDRLAKYEERQRKKQREEQRNSESRSKVLNHILNVEHVTGRSVHEIADDIVRKFPAMDVHSLLRPPRKDIQEKEEEMGWGTDSESESTNDGKGNKEEKEPESHNDILQSFGDLPAEHSGSNTPRRQRGGKSQQLEDKAAKTCSAIDDMIVDRKVTEKAVEEAVEETPEETPEETPEETPNRTSEETLVVASNKTCEELPEELPGEAKDATESVIEITEITEITEDITKNGDEEAAEEATGEVTEEVTEKTDEETANNELDAAVDVKGVEDAKDVIERPTEDIDKTPETTINDAAEKPASPSTDNAEPSSQAGHSSERERELKKARRKARKHRARMEKKNSHAEKEKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL27</accession>
    <name>A0ABR3YL27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosylphosphatidylinositol anchor biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GPI8_1</name>
        <name evidence="4" type="ORF">Sste5346_009496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000090">
        <property type="protein sequence ID" value="KAL1888540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044230">
        <property type="entry name" value="GTF3C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024761">
        <property type="entry name" value="TFIIIC_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024764">
        <property type="entry name" value="TFIIIC_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12657">
        <property type="entry name" value="TFIIIC_delta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12660">
        <property type="entry name" value="zf-TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor IIIC 90kDa subunit N-terminal" evidence="2">
        <location>
            <begin position="39"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC 90kDa subunit N-terminal" evidence="2">
        <location>
            <begin position="254"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC putative zinc-finger" evidence="3">
        <location>
            <begin position="699"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="792" mass="85397" checksum="BBCEF594025099E9" modified="2025-10-08" version="1">MPDFDMDAAGPSVRHRPRPLDLVPIDMDAAPYVVNALDWSADGGLAAATVDSVHIFTPQFQTASGNTMPIFDGRVTDGGSPPEEEIDGPVDSQFATETGARKQFGASSRRILVGYPRLDHTINMPLFDEWHLDHPTNGGGSSHGQWQADHPNISAGSGSISGSGSSMNSIVSIAWSPSGVGRNERCILGVLTASGMLIIYGEPLDGGESDGTTTNGSRNNVSGSRSSYDTSRWEVLFAVGERLAVPGQKKPGECILSFTWSGECETLEDDRLPPSEGQRRTETKALLVYQNDKKDIVVLDVGHSRHGDGRTTWKVSEAQRIKEATGVHTLPPGFSLMTDPNYVPHLTPFGLRCSPWMVEKVPVGDDRPPETILTCVVGYTASHYVGFRRLSLVLRPSVGSGERTITLDKHDTAGFCTFMSTNAILRFEDGLWSVDDDMHTGVPKKRSKCRAVVATPMEVVSYEFEFAARDPNLPVRVSGVPTDHIFGTEGECAATNPAPTQWHTNPISGLIVHPPDTRNADNGPFYSFVRRDATSIATDWHDAFSVGQDRPEWVNVIERKVTRLDGESAPDQAADAAAQSLETNTLASQDRLHVRTWGLTQAPGGLPGAGGITAVLMNECTIGDRQSGRTQRGCQILFGVQRQQPSDAASDTEPANMFASRYERPAATTEAAVWTYMYGGGPEVVSRTVGSTREGIVASQKCSICTSSIKERDEMMICTDGHSFDKCTGTGLAIQKPNVSRVCGVCGRKTLVPSALDEILTLSGIDDTNKGELYGRLLDKVCGLCGGKFFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL33</accession>
    <name>A0ABR3YL33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Sste5346_009366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000086">
        <property type="protein sequence ID" value="KAL1888740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="2">
        <location>
            <begin position="134"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="868" mass="93582" checksum="2B571991984CD63C" modified="2025-10-08" version="1">MSISGNPLAALGPISWDILDQHDLGHFLADTFTCAQILADSIPATSSSSAIPSTGRPRSQTDGAVSYGLHSAPVSHHGSGTATPSPEDMSAKAEKLRQDLRQSWKEVKTGGSNPRDIVVYKMNGGREGYAGSSWFARRSLHRIEKGKLPTASKTKDKKVLADVPDVEIGFDMFRKALLKEFSLPEQKKEGEASTVRTMITKKRLEHVVVDGQEHDAVDKVEAENVDGNVADAISRQLDVYLLEAEFPGPTATRDFVTMLLTTQSPCQTAGHDHRDHSLRQFMLVSKPCDHPETPQRSGYVRAQYESVEVIREVRVPAKPTMGLAKNIRKTRSSIDLSHGDVDTDASDLDTDGHDIAIEWLMITRNNPGGNVPRFLVDKSTPSSIISDANKFLDWLVAQQVEATMKEEVSKPEVQTVVAGAGPGKPVTATPLAAAIPEEEEEETGEKAVSVDEVSDTGFATEDTPENNNRSGASPSVTILSLESSGGAASSAKLFNMLSGALGGAGTAVASKLPNPFGGAVEALHSSFEDHPLGDEDDGIDTTDDTDNTYSDIDDEDEDGDKSRGRSRRSTQDETSVSTDKSAPDNASVASIPPPPPTTALEMLAHDRALALCKLNDRSSTGLSTGGSSVAASDVDNDTETGSATTSSKQQKKIEQEAAAKAAKAAKAAEAARKKHEKELQKLQDKQKKAEAEILKANKGKKDANPVEVVKEEEVGSSAQSTKSSKSTKSVTDSTTGAAAADHSSTSSLPDDPANTELQKLREKHDRAVARQKAQYQKEMEKLEKKRQQQAEKEAARLRKQQERDEKNDTARQLTHARAERDVARKEVQVLTERVRQLEAQNELLAAEVAQSTGKSKLHAKVEDAEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLS3</accession>
    <name>A0ABR3YLS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000081">
        <property type="protein sequence ID" value="KAL1888995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1243"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1475"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1588"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1492"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1508"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1593"/>
            <end position="1613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1711" mass="186900" checksum="B0515EDFC037BDE4" modified="2025-10-08" version="1">MSQCAGRGPDRGGHNNNAGPGGSNNKHTSSSSPTMKSSYNHNGGHNSNGGTWNVWTNKRNSGGTVTNATNNSNNSHNNLKHGTRVNSAGSPSSVTYQIPNVVSPSTHSPHSSPPRPFLPLPPSVQAPVPTSMPPLPHGPHGPPAMHGPSPPDYRQGSHNMNHGYSHAHIPHGSPPIGADYARGFNGTKYTRRGHLNNNQFYTNGGSNGNNGGPVRGGGSNDGNRIGSNHSSHSNHSGGGSHGRQNSHGSQATSNNNGQSLDIVKIKNDAFKAGRLHGYQDGYREAQRVFYNEGHRDGHREGHGEGHKEGHKEGLREGQKEGHRLGYKEGHRAGHRDGHQEGRQAGHREGHQEGHQAGYHEGYYQGHYTSHQDGYDQGHGDGYEEGFRWASTFWTPAPLKPDAPEFVPGGAGGQYSSPVVVDGSSGRSVDHVKFRKWLNDVEYRKLARPVRADMAKNGVVALSIDSPVDQESTQGTVIHHDEAVDYHHTEHPSDNQVENAVDGHQANESVDNYAVQNVDQAVDQYDGQLVDIEAYEPVAPRVEVSVEHHVGHPTHAGDIQPAQAHVEDHADHISEQLIDLDSPKAVEEKTAVYAVSVGAVDKADEANDSSDDLLVTPHEDQVVVCGSFDTAFYAKIDKQLDDFCQTLGEQMMNDFNCILDQHDQGREERLQQFAELSDKLMARADDMGVEITKELEEAHPEEEAPEDAPELMVDTTSIDSPVRSPIIYPSPASTPSHPQMPFMPRVARPAGPQIVSLSRPVSPQSPKCPKLPESVATVIHDYPTEKENFPKMITFGDVPVIITEKIKCHIVKPAPAPTPTPVAIVEATPPPIVETTPLAVVEASPPAIIEDNPTLINKNVEAEEDCASDTATVDDHSTAAFELLDDDTSEPVEPTEATRDVIYPFPPPAPKAVAPKVTGFVQYKKKKGKGKKKAKKAAQVKAAQAKASSSPVVVEDKAEVVVFTPPVEPRPTMKFEDISIFSSDGPEPILGHYHSKLYQAQPIFEIGPDQAPQITESYPTFRNRPRHSRTSAYSFNAHQLLDPIVEIHDKDGVVFPVGGRTPPRGIVRQVPDHVVYKFGIPPANFVAYNDPSDSSGDEKGNRPPVGTELLARCVQHGLSTCPMCAITPSFRFLGPGESVSRTLEYNGKPAGDSQTSPAIFWRFRPAGFSDFEVHGHQLVESSFAAAQHPDEANPFCHMRMMPQYDAEVLGHHVQGEHAKEKPVPPSDLDTYCCDQCGGLTWLVTRRSRPNGGGPNGGNNSSSTTTGDRTFGKQHPSHHATFNEAWARSRSFCRTMVDGGRGENRFPEQAGTTRSLFVEIASVLAVTKKGTNDSNGGHARFGLAAYFGPNSRHNSRLDLDMATASMETARDAVASDGNNRTRLVDLPFEQFTINAGPIAAVAVALHRLWTDVVPMHRSAIDRVTRYNSDHSRRKAYRFRAIIMTDSQYVVDLFSDNIHKRWKRKFKPYEDTVMTDAIGEGKDEGNTGEAISTKTKTKKKSKPKKRKTKKQKEEVAKKRADEEEAEQALLAATDGGKAIRVTTTVVTDEYTEYEIEPAATNSNNSNNPNKRKASMLDDLIDLDLATRGRHRNRAFSVSTTTPTSSRSNSRSRSHSPPMKRLTPVVQQSDDVTSGGLFAPLLGPPTRDELDFDRPDGRFVYASQRGGPPLSNGILVQLVRRYIELLRWHGVKVAFYEVDSKYVQGARSLAEEVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM64</accession>
    <name>A0ABR3YM64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidyl synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Sste5346_009034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000077">
        <property type="protein sequence ID" value="KAL1889278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF4">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="51482" checksum="76D2F268FC728B7D" modified="2025-10-08" version="1">MSSNRLQRPAGPNRTASASSFAEAFSIARRNLETEISHEEPVFSPTDELSSPDLPPTNAPSLSNSNVITPASLVTPLTEPDTPFNGESDYEDDVADNFAFAFDIDGVLVRGGKPIPEAIEAMKMLNGENEYGIRVPYIFLTNGGGKTEAERCLDLSAQLELEVSPGQFICGHTPMRELADKYRGAVLVVGGEGEKCRSVAEHYGFKDVITPGDIIKANAATAPFRKLTEQEHANSRDLLSRRGIDKMSDIVIEAVFVFADSRDWASDLQIILDIAMSKGGRLETRSETFDEGPPIYFSHSDVVWSAAHEHVRLGMGALRRIVETVFSDVTGGKTLTTHAFGKPQVSTFEFATRLLQQWRATQHGLVGSRPLDTVYFVGDTPESDIRGTNAMDARSKHTSWYSVLVKTGVYQDGTEPAYTPKAVVPTVLDAVRHGIEREMQARKARQSKMDAKNQGAIIEKLATIEIQDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN75</accession>
    <name>A0ABR3YN75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CTK2</name>
        <name evidence="4" type="ORF">Sste5346_008744</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 5346</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000070">
        <property type="protein sequence ID" value="KAL1889756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="3">
        <location>
            <begin position="73"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583186"/>
        </source>
    </evidence>
    <sequence length="531" mass="57398" checksum="EBAB6940001395B0" modified="2025-10-08" version="1">MGRRGPRHGGGGGGGFRQGGGNSNNNQNHGGGGNNSHNAHPPPPPPPSQPQIITKEHPPVNGPNPGYIAVGSQYLLEQQLRQMQRETGCDPAREDSYRLQGVQLIDNVRQALQLPVKTFATACTYYHKFRLNFRDAEYNFQDAALSALFVACKVEDTIKKSKEVLCAAYNLKNPDKPTTPDDKIFERPSTIIVGLDRLILQTVGFDFRVRHPQKLLIKLIRQLIPEEDAREFLSVAYPVSIDLYKTFAPIKQTSFTMALAVIELTARILDDKHLDRVRHLTTMTNHGGNDYHTSRSCVVETLLDLLDLYTQFTKSTKVGTRFDLHRFIDIKIKINQEVDDNPALQRTDGWCDRCAGDGLGVGIQTPGSVTSPATTGSGPNGAGGAGGGGASGVIGASAKPRKHAGSMRFLFEVDKMRQEQTEVAEYFKEEYTEEEVEVDELIPEPTRGGGGGGGGGGGNQQHNGNGNNGNNRNHGPPRRERNNHNNGGGGGGGGGGGGGGGGNGDPNWGPYQRSRNNDHRQNKGRKGGGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNU3</accession>
    <name>A0ABR3YNU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ornithine decarboxylase antizyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Sste5346_008470</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Sporothrix stenoceras</name>
        <dbReference type="NCBI Taxonomy" id="5173"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Ophiostomatales</taxon>
            <taxon>Ophiostomataceae</taxon>
            <taxon>Sporothrix</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 5346</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with ODC and thereby sterically blocks ODC homodimerization.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ODC antizyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWCUI010000066">
        <property type="protein sequence ID" value="KAL1890035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583186">
        <property type="component" value="Unas
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